#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P61964 uniprotkb:Q8NFC6 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-2654318|uniprotkb:Q9NTD6|uniprotkb:Q96AL1|uniprotkb:Q9H6G0|uniprotkb:Q6P0M8|uniprotkb:Q9P2L9|ensembl:ENSP00000040738 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:bd1l1_human(display_long)|uniprotkb:BOD1L1(gene name)|psi-mi:BOD1L1(display_short)|uniprotkb:BOD1L(gene name synonym)|uniprotkb:FAM44A(gene name synonym)|uniprotkb:KIAA1327(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25470797|imex:IM-26985-361 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N refseq:NP_683692.2|ensembl:ENSG00000038219(gene)|ensembl:ENST00000040738(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR043244|mint:Q8NFC6 - - - figure legend:F3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/17 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:/sFfw7CP8rOZG3hZNsT0npwIZIQ9606 rigid:fmdlCkwib0qLzVj7MlfL04L7rGg false tandem tag:n-n - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P61964 uniprotkb:O15550 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-4292203|uniprotkb:Q52LL9|uniprotkb:Q5JVQ7|intact:EBI-28988602|ensembl:ENSP00000367203 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:kdm6a_human(display_long)|uniprotkb:KDM6A(gene name)|psi-mi:KDM6A(display_short)|uniprotkb:UTX(gene name synonym)|uniprotkb:Histone demethylase UTX(gene name synonym)|uniprotkb:Ubiquitously-transcribed TPR protein on the X chromosome(gene name synonym)|uniprotkb:Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(27) demethylase 6A"(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25470803|imex:IM-26985-301 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N refseq:NP_066963.2|ensembl:ENSG00000147050(gene)|ensembl:ENST00000377967(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007507"(heart development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071557"(histone H3-K27 demethylation)|go:"GO:0071558"(histone H3-tri/di-methyl-lysine-27 demethylase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:O15550|rcsb pdb:3AVR|rcsb pdb:3AVS|rcsb pdb:6FUK|rcsb pdb:6FUL|reactome:R-HSA-3214842|reactome:R-HSA-5617472|ensembl:ENSP00000367203|dip:DIP-46192N - - - figure legend:F3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/17 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:sqg+Ikkgvz0uT/gMx1wYs9FaDbI9606 rigid:BC5I7+yqZqnMg7ONBxfeEIQsDpg false tandem tag:n-n - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P61964 uniprotkb:O14686 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-996065|uniprotkb:O14687|intact:EBI-28986759|ensembl:ENSP00000301067 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:kmt2d_human(display_long)|uniprotkb:KMT2D(gene name)|psi-mi:KMT2D(display_short)|uniprotkb:ALL1-related protein(gene name synonym)|uniprotkb:ALR(gene name synonym)|uniprotkb:MLL2(gene name synonym)|uniprotkb:MLL4(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25470809|imex:IM-26985-441 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N refseq:NP_003473.3|refseq:XP_006719677.1|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0043627"(response to estrogen)|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:1904837"(beta-catenin-TCF complex assembly)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR009071(High mobility group box, HMG)|ensembl:ENSG00000167548(gene)|ensembl:ENST00000301067(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001555"(oocyte growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|interpro:IPR036910|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR037890|interpro:IPR041961|interpro:IPR041964|mint:O14686|rcsb pdb:3UVK|rcsb pdb:4ERQ|rcsb pdb:4Z4P|rcsb pdb:6O7G|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR034732|ensembl:ENSP00000301067|refseq:XP_005269219.1|dip:DIP-37875N - - - figure legend:F3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/17 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:eaCGHR6OqxzL66VYfOrzBWJApHY9606 rigid:VRq5hKH+kgo5iJPTSFx9EYj37is false tandem tag:n-n - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P61964 uniprotkb:O00255 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-592789|uniprotkb:O00632|uniprotkb:Q9BUK2|uniprotkb:A5HBC6|uniprotkb:A5HBC7|uniprotkb:A5HBC8|uniprotkb:A5HBC9|uniprotkb:A5HBD0|uniprotkb:A5HBD1|uniprotkb:A5HBD2|uniprotkb:Q9BUF0|ensembl:ENSP00000366530 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:men1_human(display_long)|uniprotkb:MEN1(gene name)|psi-mi:MEN1(display_short)|uniprotkb:SCG2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25470815|imex:IM-26985-521 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N refseq:NP_000235.2|refseq:NP_570711.1|refseq:NP_570712.1|refseq:NP_570713.1|refseq:NP_570714.1|refseq:NP_570715.1|refseq:NP_570716.1|refseq:XP_005274058.1|refseq:XP_016873258.1|refseq:XP_016873259.1|dip:DIP-24236N|ensembl:ENSG00000133895(gene)|ensembl:ENST00000377313(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002076"(osteoblast development)|go:"GO:0003309"(type B pancreatic cell differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009411"(response to UV)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032925"(regulation of activin receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046697"(decidualization)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0061469"(regulation of type B pancreatic cell proliferation)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071559"(response to transforming growth factor beta)|go:"GO:1902807"(negative regulation of cell cycle G1/S phase transition)|interpro:IPR007747(Menin)|mint:O00255|rcsb pdb:3U84|rcsb pdb:3U85|rcsb pdb:3U86|rcsb pdb:3U88|rcsb pdb:4GPQ|rcsb pdb:4GQ3|rcsb pdb:4GQ4|rcsb pdb:4GQ6|rcsb pdb:4I80|rcsb pdb:4OG3|rcsb pdb:4OG4|rcsb pdb:4OG5|rcsb pdb:4OG6|rcsb pdb:4OG7|rcsb pdb:4OG8|rcsb pdb:4X5Y|rcsb pdb:4X5Z|rcsb pdb:5DB0|rcsb pdb:5DB1|rcsb pdb:5DB2|rcsb pdb:5DB3|rcsb pdb:5DD9|rcsb pdb:5DDA|rcsb pdb:5DDB|rcsb pdb:5DDC|rcsb pdb:5DDD|rcsb pdb:5DDF|rcsb pdb:6B41|rcsb pdb:6BXH|rcsb pdb:6BXY|rcsb pdb:6BY8|rcsb pdb:6E1A|rcsb pdb:6O5I|rcsb pdb:6OPJ|rcsb pdb:6PKC|rcsb pdb:6WNH|reactome:R-HSA-201722|reactome:R-HSA-2173796|reactome:R-HSA-3769402|reactome:R-HSA-381426|reactome:R-HSA-5626467|reactome:R-HSA-8957275|rcsb pdb:5DDE - - - figure legend:F3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/17 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:gXAt4cxheS3wgMbFtc8ACfkHRH09606 rigid:qLFEDvdnTb8SrCTZlzuI4WvhLg0 false tandem tag:n-n - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:P61964 uniprotkb:Q8IYH5 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-2795524|uniprotkb:B7WPC6|uniprotkb:Q6N004|uniprotkb:Q6N070|uniprotkb:Q8IYP0|uniprotkb:Q8IYR1|uniprotkb:Q8TEK4|uniprotkb:Q9Y4U0|ensembl:ENSP00000359837 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:zzz3_human(display_long)|uniprotkb:ZZZ3(gene name)|psi-mi:ZZZ3(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25470821|imex:IM-26985-61 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N refseq:NP_001295166.1|refseq:NP_056349.1|refseq:XP_016856459.1|refseq:XP_005270782.1|refseq:XP_005270783.1|refseq:XP_005270784.1|refseq:XP_005270786.1|ensembl:ENSG00000036549(gene)|ensembl:ENST00000370801(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR037830|interpro:IPR041981|interpro:IPR043145|rcsb pdb:2FC7|rcsb pdb:2YUM|rcsb pdb:6E83|rcsb pdb:6E86|reactome:R-HSA-3214847|mint:Q8IYH5|dip:DIP-47289N - - - figure legend:F3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/17 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:F8aEW+XePZMAIrIAIDMEnBXdSBo9606 rigid:BKfl42Ac+9QFP9FKGvSjp8dmm+s false tandem tag:n-n - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8NHM5 uniprotkb:Q13185 intact:EBI-3955564|uniprotkb:Q1RLM7|uniprotkb:Q8NCI2|uniprotkb:Q96HC7|uniprotkb:Q96SL0|uniprotkb:Q96T03|uniprotkb:Q9NS96|uniprotkb:Q9UF75|ensembl:ENSP00000366271|uniprotkb:A8MRS1 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 psi-mi:kdm2b_human(display_long)|uniprotkb:KDM2B(gene name)|psi-mi:KDM2B(display_short)|uniprotkb:CXXC2(gene name synonym)|uniprotkb:FBL10(gene name synonym)|uniprotkb:FBXL10(gene name synonym)|uniprotkb:JHDM1B(gene name synonym)|uniprotkb:PCCX2(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 2(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 10(gene name synonym)|uniprotkb:F-box protein FBL10(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 10(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1B(gene name synonym)|uniprotkb:Jumonji domain-containing EMSY-interactor methyltransferase motif protein(gene name synonym)|uniprotkb:Protein-containing CXXC domain 2(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1B(gene name synonym)|uniprotkb:NDY1(gene name synonym) psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25470829|imex:IM-26985-221 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENST00000377071(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0021555"(midbrain-hindbrain boundary morphogenesis)|go:"GO:0021592"(fourth ventricle development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021678"(third ventricle development)|go:"GO:0021993"(initiation of neural tube closure)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|interpro:IPR041070|interpro:IPR041667|mint:Q8NHM5|rcsb pdb:4O64|rcsb pdb:5JH5|rcsb pdb:6BVA|reactome:R-HSA-3214842|refseq:NP_115979.3|ensembl:ENSG00000089094(gene)|refseq:NP_001005366.1 go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N - - - figure legend:F3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/17 rogid:tnMbfP2oxwaaDyHHAigNt5hx4hM9606 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rigid:b3Qytq2MeDeglx7j1i68+06MGyY false - tandem tag:n-n - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q5VUG0 uniprotkb:O60341 intact:EBI-12025260|ensembl:ENSP00000355109|ensembl:ENSP00000380353|uniprotkb:A7MD09|uniprotkb:Q9HCF5 intact:EBI-710124|uniprotkb:Q5TH94|uniprotkb:Q5TH95|uniprotkb:Q86VT7|uniprotkb:Q8IXK4|uniprotkb:Q8NDP6|uniprotkb:Q8TAZ3|uniprotkb:Q96AW4|ensembl:ENSP00000349049|uniprotkb:A8MWP9 psi-mi:smbt2_human(display_long)|uniprotkb:SFMBT2(gene name)|psi-mi:SFMBT2(display_short)|uniprotkb:KIAA1617(gene name synonym) psi-mi:kdm1a_human(display_long)|uniprotkb:Flavin-containing amine oxidase domain-containing protein 2(gene name synonym)|uniprotkb:BRAF35-HDAC complex protein BHC110(gene name synonym)|uniprotkb:KDM1A(gene name)|psi-mi:KDM1A(display_short)|uniprotkb:KIAA0601(gene name synonym)|uniprotkb:LSD1(gene name synonym)|uniprotkb:AOF2(gene name synonym)|uniprotkb:KDM1(gene name synonym)|uniprotkb:"[histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A"(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25470836|imex:IM-26985-443 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000198879(gene)|ensembl:ENST00000361972(transcript)|ensembl:ENST00000397167(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016235"(aggresome)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0042393"(histone binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR037604|interpro:IPR038348|mint:Q5VUG0|rcsb pdb:1WJR|refseq:NP_001018049.1|refseq:NP_001025051.1|refseq:XP_011517913.1|refseq:XP_016871955.1 go:"GO:0021987"(cerebral cortex development)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032451"(demethylase activity)|refseq:NP_001009999.1|refseq:NP_055828.2|ensembl:ENSG00000004487(gene)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|ensembl:ENST00000356634(transcript)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|dip:DIP-34641N|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0033184"(positive regulation of histone ubiquitination)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042551"(neuron maturation)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043426"(MRF binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046098"(guanine metabolic process)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0060992"(response to fungicide)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061752"(telomeric repeat-containing RNA binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1903827"|go:"GO:1990391"(DNA repair complex)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2000648"(positive regulation of stem cell proliferation)|interpro:IPR002937(Amine oxidase)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017366(Histone lysine-specific demethylase)|interpro:IPR036188|interpro:IPR036388|mint:O60341|rcsb pdb:2COM|rcsb pdb:2DW4|rcsb pdb:2EJR|rcsb pdb:2H94|rcsb pdb:2HKO|rcsb pdb:2IW5|rcsb pdb:2L3D|rcsb pdb:2UXN|rcsb pdb:2UXX|rcsb pdb:2V1D|rcsb pdb:2X0L|rcsb pdb:2XAF|rcsb pdb:2XAG|rcsb pdb:2XAH|rcsb pdb:2XAJ|rcsb pdb:2XAQ|rcsb pdb:2XAS|rcsb pdb:2Y48|rcsb pdb:2Z3Y|rcsb pdb:2Z5U|rcsb pdb:3ABT|rcsb pdb:3ABU|rcsb pdb:3ZMS|rcsb pdb:3ZMT|rcsb pdb:3ZMU|rcsb pdb:3ZMV|rcsb pdb:3ZMZ|rcsb pdb:3ZN0|rcsb pdb:3ZN1|rcsb pdb:4BAY|rcsb pdb:4CZZ|rcsb pdb:4KUM|rcsb pdb:4UV8|rcsb pdb:4UV9|rcsb pdb:4UVA|rcsb pdb:4UVB|rcsb pdb:4UVC|rcsb pdb:4UXN|rcsb pdb:4XBF|rcsb pdb:5AFW|rcsb pdb:5H6Q|rcsb pdb:5H6R|rcsb pdb:5IT3|rcsb pdb:5L3B|rcsb pdb:5L3C|rcsb pdb:5L3D|rcsb pdb:5L3E|rcsb pdb:5L3F|rcsb pdb:5L3G|rcsb pdb:5LBQ|rcsb pdb:5LGN|rcsb pdb:5LGT|rcsb pdb:5LGU|rcsb pdb:5LHG|rcsb pdb:5LHH|rcsb pdb:5LHI|rcsb pdb:5X60|rcsb pdb:5YJB|rcsb pdb:6E1F|rcsb pdb:6K3E|rcsb pdb:6KGK|rcsb pdb:6KGL|rcsb pdb:6KGM|rcsb pdb:6KGN|rcsb pdb:6KGO|rcsb pdb:6KGP|rcsb pdb:6KGQ|rcsb pdb:6KGR|rcsb pdb:6NQM|rcsb pdb:6NQU|rcsb pdb:6NR5|rcsb pdb:6S35|rcsb pdb:6TE1|rcsb pdb:6VYP|rcsb pdb:6W4K|rcsb pdb:6WC6|rcsb pdb:7CDC|rcsb pdb:7CDD|rcsb pdb:7CDE|rcsb pdb:7CDF|rcsb pdb:7CDG|rcsb pdb:7E0G|rcsb pdb:7JJL|rcsb pdb:7JJM|rcsb pdb:7JK7|reactome:R-HSA-3214815|reactome:R-HSA-3214842|reactome:R-HSA-5625886|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9029569|reactome:R-HSA-9679191|reactome:R-HSA-983231 - - - figure legend:F3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/17 rogid:ekByFM3jqM1sgzg6rpUmrMmiBPc9606 rogid:rS9F23Rg1Ha6XOQSisWQfhKVFfs9606 rigid:AhBw6s3/8BwZWpYB0IHX3plPYMU false tandem tag:n-n - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q96EW2 uniprotkb:Q6IQ49 intact:EBI-720457|uniprotkb:Q6P476|uniprotkb:Q8N8J4|uniprotkb:Q8NHH6|uniprotkb:Q8WWF0|ensembl:ENSP00000302562 intact:EBI-2362709|uniprotkb:Q5TD36|uniprotkb:Q6ZS26|uniprotkb:Q8NAG7|uniprotkb:A8K4P3|ensembl:ENSP00000272091 psi-mi:hbap1_human(display_long)|uniprotkb:27 kDa heat shock protein-associated protein 1(gene name synonym)|uniprotkb:Protein associated with small stress protein 1(gene name synonym)|uniprotkb:HSPBAP1(gene name)|psi-mi:HSPBAP1(display_short)|uniprotkb:PASS1(gene name synonym) psi-mi:sde2_human(display_long)|uniprotkb:SDE2(gene name)|psi-mi:SDE2(display_short)|uniprotkb:C1orf55(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25470842|imex:IM-26985-223 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078886.2|ensembl:ENSG00000169087(gene)|ensembl:ENST00000306103(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR013296("Protein Associated with Small Stress protein 1 (PASS1)")|interpro:IPR041667|mint:Q96EW2|refseq:NP_001307657.1|refseq:XP_005247819.1 refseq:NP_689821.3|ensembl:ENSG00000143751(gene)|ensembl:ENST00000272091(transcript)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0016485"(protein processing)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016607"(nuclear speck)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0034644"(cellular response to UV)|go:"GO:0051301"(cell division)|interpro:IPR024974|mint:Q6IQ49|rcsb pdb:6QDV - - - figure legend:F3B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/17 rogid:5KvIFh1GwZSyAKD2EloRz2oweNk9606 rogid:ykYmjWUVmJODk3kwvOO7oYwjdao9606 rigid:qj5vB4CBiWtRXKV7Vc5cd9UbkVc false tandem tag:?-? - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:A6NED2 uniprotkb:Q8N371 intact:EBI-21552314|ensembl:ENSP00000377801|ensembl:ENSP00000451963|uniprotkb:B2RTP9|uniprotkb:Q29RX6 intact:EBI-750326|uniprotkb:B4DLU9|uniprotkb:Q6VAK5|uniprotkb:Q9H8B1|ensembl:ENSP00000286096 psi-mi:rccd1_human(display_long)|uniprotkb:RCCD1(gene name)|psi-mi:RCCD1(display_short) psi-mi:kdm8_human(display_long)|uniprotkb:KDM8(gene name)|psi-mi:KDM8(display_short)|uniprotkb:JMJD5(gene name synonym)|uniprotkb:JmjC domain-containing protein 5(gene name synonym)|uniprotkb:Jumonji C domain-containing protein 5(gene name synonym)|uniprotkb:"L-arginine (3R)-hydroxylase KDM8"(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25470848|imex:IM-26985-141 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166965(gene)|ensembl:ENST00000394258(transcript)|ensembl:ENST00000556618(transcript)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|mint:A6NED2|rcsb pdb:6F4R|rcsb pdb:6F4S|rcsb pdb:6F4T|refseq:NP_001017919.1|refseq:NP_291022.2 refseq:NP_001138820.1|refseq:NP_079049.2|ensembl:ENSG00000155666(gene)|ensembl:ENST00000286096(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003682"(chromatin binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0031648"(protein destabilization)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:0140554"|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR041667|mint:Q8N371|rcsb pdb:3UYJ|rcsb pdb:4AAP|rcsb pdb:6F4T|rcsb pdb:6I9L|rcsb pdb:6I9M|rcsb pdb:6I9N|rcsb pdb:4GAZ|rcsb pdb:4GJY|rcsb pdb:4GJZ|rcsb pdb:4QU1|rcsb pdb:5FBJ|rcsb pdb:6AVS|rcsb pdb:6AX3|rcsb pdb:6F4M|rcsb pdb:6F4N|rcsb pdb:6F4O|rcsb pdb:6F4P|rcsb pdb:6F4Q|rcsb pdb:6F4R|rcsb pdb:6F4S - - - figure legend:F4B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/17 rogid:pJ4TNM7dmfISs5RIVzio/hBYHp09606 rogid:xMY4ykJyXdyFo1lNfe6RekrAAhE9606 rigid:4z3qg6jzsPt6ec6dnIOiwHvEOJE false flag tag:?-?|necessary binding region:1-169 - - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot) uniprotkb:Q8N7H5 uniprotkb:Q8WVC0 intact:EBI-2607770|uniprotkb:O75239|uniprotkb:Q9H166|uniprotkb:Q9NUU9|ensembl:ENSP00000221265|uniprotkb:M0QX35 intact:EBI-932432|uniprotkb:Q96N99|ensembl:ENSP00000299601 psi-mi:paf1_human(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:PD2(gene name synonym)|uniprotkb:Pancreatic differentiation protein 2(gene name synonym) psi-mi:leo1_human(display_long)|uniprotkb:LEO1(gene name)|psi-mi:LEO1(display_short)|uniprotkb:RDL(gene name synonym)|uniprotkb:Replicative senescence down-regulated leo1-like protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25471035|imex:IM-26985-363 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061961.2|ensembl:ENSG00000006712(gene)|ensembl:ENST00000221265(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030054"(cell junction)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|mint:Q8N7H5|rcsb pdb:4M6T|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|refseq:NP_001243755.1|dip:DIP-48673N refseq:NP_001273359.1|refseq:NP_620147.1|dip:DIP-37885N|ensembl:ENSG00000166477(gene)|ensembl:ENST00000299601(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|interpro:IPR007149(Leo1-like protein)|mint:Q8WVC0|rcsb pdb:4M6T|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-201722|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654 - - - figure legend:ST2|comment:"Two-step purifications decrease the number of nonspecific binders while preserving specific ones (Table S2)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/17 rogid:5Bf9gSdxgaufI30DVL8QAyVLqNk9606 rogid:o0aaW4nxzWuPZ8/pMZpa9Qz9oEA9606 rigid:hXXhlT4Lb3VAQl1O/QlawlROfSE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N7H5 uniprotkb:Q9GZS3 intact:EBI-2607770|uniprotkb:O75239|uniprotkb:Q9H166|uniprotkb:Q9NUU9|ensembl:ENSP00000221265|uniprotkb:M0QX35 intact:EBI-358545|uniprotkb:D3DW84|uniprotkb:Q6IA22|uniprotkb:Q7Z4X4|ensembl:ENSP00000267973|ensembl:ENSP00000453801 psi-mi:paf1_human(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:PD2(gene name synonym)|uniprotkb:Pancreatic differentiation protein 2(gene name synonym) psi-mi:wdr61_human(display_long)|uniprotkb:WDR61(gene name)|psi-mi:WDR61(display_short)|uniprotkb:Meiotic recombination REC14 protein homolog(gene name synonym)|uniprotkb:SKI8 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25471035|imex:IM-26985-363 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061961.2|ensembl:ENSG00000006712(gene)|ensembl:ENST00000221265(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030054"(cell junction)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|mint:Q8N7H5|rcsb pdb:4M6T|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|refseq:NP_001243755.1|dip:DIP-48673N refseq:NP_079510.1|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9GZS3|rcsb pdb:3OW8|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-429958|reactome:R-HSA-674695|reactome:R-HSA-75955|ensembl:ENSG00000140395(gene)|ensembl:ENST00000267973(transcript)|ensembl:ENST00000558311(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0055087"(Ski complex)|reactome:R-HSA-8866654|refseq:XP_011520396.1|refseq:NP_001290176.1|refseq:NP_001290177.1|dip:DIP-36672N - - - figure legend:ST2|comment:"Two-step purifications decrease the number of nonspecific binders while preserving specific ones (Table S2)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/17 rogid:5Bf9gSdxgaufI30DVL8QAyVLqNk9606 rogid:yVcjv2BXXr3VFSR7OcJ/1u9L6gw9606 rigid:hXXhlT4Lb3VAQl1O/QlawlROfSE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N7H5 uniprotkb:Q6P1J9 intact:EBI-2607770|uniprotkb:O75239|uniprotkb:Q9H166|uniprotkb:Q9NUU9|ensembl:ENSP00000221265|uniprotkb:M0QX35 intact:EBI-930143|uniprotkb:A6NLZ8|uniprotkb:Q6PK51|uniprotkb:Q96A07|uniprotkb:Q9H245|uniprotkb:Q9H5L7|uniprotkb:B2RBR2|ensembl:ENSP00000356405 psi-mi:paf1_human(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:PD2(gene name synonym)|uniprotkb:Pancreatic differentiation protein 2(gene name synonym) psi-mi:cdc73_human(display_long)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:C1orf28(gene name synonym)|uniprotkb:HRPT2(gene name synonym)|uniprotkb:Cell division cycle protein 73 homolog(gene name synonym)|uniprotkb:Hyperparathyroidism 2 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25471035|imex:IM-26985-363 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061961.2|ensembl:ENSG00000006712(gene)|ensembl:ENST00000221265(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030054"(cell junction)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|mint:Q8N7H5|rcsb pdb:4M6T|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|refseq:NP_001243755.1|dip:DIP-48673N refseq:NP_078805.3|dip:DIP-37884N|ensembl:ENSG00000134371(gene)|ensembl:ENST00000367435(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0031648"(protein destabilization)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR032041|interpro:IPR038103|mint:Q6P1J9|rcsb pdb:5YDE|rcsb pdb:5YDF|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-201722|reactome:R-HSA-5632684|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654 - - - figure legend:ST2|comment:"Two-step purifications decrease the number of nonspecific binders while preserving specific ones (Table S2)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/17 rogid:5Bf9gSdxgaufI30DVL8QAyVLqNk9606 rogid:nuJ2kK0petj8iBr17I2BQzxcVmE9606 rigid:hXXhlT4Lb3VAQl1O/QlawlROfSE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N7H5 uniprotkb:Q6PD62 intact:EBI-2607770|uniprotkb:O75239|uniprotkb:Q9H166|uniprotkb:Q9NUU9|ensembl:ENSP00000221265|uniprotkb:M0QX35 intact:EBI-1019583|uniprotkb:Q15015|uniprotkb:D3DQV8|ensembl:ENSP00000355013 psi-mi:paf1_human(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:PD2(gene name synonym)|uniprotkb:Pancreatic differentiation protein 2(gene name synonym) psi-mi:ctr9_human(display_long)|uniprotkb:CTR9(gene name)|psi-mi:CTR9(display_short)|uniprotkb:KIAA0155(gene name synonym)|uniprotkb:SH2BP1(gene name synonym)|uniprotkb:SH2 domain-binding protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25471035|imex:IM-26985-363 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061961.2|ensembl:ENSG00000006712(gene)|ensembl:ENST00000221265(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030054"(cell junction)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|mint:Q8N7H5|rcsb pdb:4M6T|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|refseq:NP_001243755.1|dip:DIP-48673N refseq:NP_055448.1|ensembl:ENSG00000198730(gene)|ensembl:ENST00000361367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001826"(inner cell mass cell differentiation)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001832"(blastocyst growth)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0035327"|go:"GO:0042169"(SH2 domain binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:2000653"(regulation of genetic imprinting)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031101|mint:Q6PD62|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|dip:DIP-31693N - - - figure legend:ST2|comment:"Two-step purifications decrease the number of nonspecific binders while preserving specific ones (Table S2)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/17 rogid:5Bf9gSdxgaufI30DVL8QAyVLqNk9606 rogid:zEFAxq/VxkK8za6qsK0gcU+EU8o9606 rigid:hXXhlT4Lb3VAQl1O/QlawlROfSE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6PD62 uniprotkb:Q8WVC0 intact:EBI-1019583|uniprotkb:Q15015|uniprotkb:D3DQV8|ensembl:ENSP00000355013 intact:EBI-932432|uniprotkb:Q96N99|ensembl:ENSP00000299601 psi-mi:ctr9_human(display_long)|uniprotkb:CTR9(gene name)|psi-mi:CTR9(display_short)|uniprotkb:KIAA0155(gene name synonym)|uniprotkb:SH2BP1(gene name synonym)|uniprotkb:SH2 domain-binding protein 1(gene name synonym) psi-mi:leo1_human(display_long)|uniprotkb:LEO1(gene name)|psi-mi:LEO1(display_short)|uniprotkb:RDL(gene name synonym)|uniprotkb:Replicative senescence down-regulated leo1-like protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25471055|imex:IM-26985-303 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055448.1|ensembl:ENSG00000198730(gene)|ensembl:ENST00000361367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001826"(inner cell mass cell differentiation)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001832"(blastocyst growth)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0035327"|go:"GO:0042169"(SH2 domain binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:2000653"(regulation of genetic imprinting)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031101|mint:Q6PD62|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|dip:DIP-31693N refseq:NP_001273359.1|refseq:NP_620147.1|dip:DIP-37885N|ensembl:ENSG00000166477(gene)|ensembl:ENST00000299601(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|interpro:IPR007149(Leo1-like protein)|mint:Q8WVC0|rcsb pdb:4M6T|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-201722|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654 - - - figure legend:ST2|comment:"Two-step purifications decrease the number of nonspecific binders while preserving specific ones (Table S2)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/17 rogid:zEFAxq/VxkK8za6qsK0gcU+EU8o9606 rogid:o0aaW4nxzWuPZ8/pMZpa9Qz9oEA9606 rigid:hXXhlT4Lb3VAQl1O/QlawlROfSE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6PD62 uniprotkb:Q9GZS3 intact:EBI-1019583|uniprotkb:Q15015|uniprotkb:D3DQV8|ensembl:ENSP00000355013 intact:EBI-358545|uniprotkb:D3DW84|uniprotkb:Q6IA22|uniprotkb:Q7Z4X4|ensembl:ENSP00000267973|ensembl:ENSP00000453801 psi-mi:ctr9_human(display_long)|uniprotkb:CTR9(gene name)|psi-mi:CTR9(display_short)|uniprotkb:KIAA0155(gene name synonym)|uniprotkb:SH2BP1(gene name synonym)|uniprotkb:SH2 domain-binding protein 1(gene name synonym) psi-mi:wdr61_human(display_long)|uniprotkb:WDR61(gene name)|psi-mi:WDR61(display_short)|uniprotkb:Meiotic recombination REC14 protein homolog(gene name synonym)|uniprotkb:SKI8 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25471055|imex:IM-26985-303 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055448.1|ensembl:ENSG00000198730(gene)|ensembl:ENST00000361367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001826"(inner cell mass cell differentiation)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001832"(blastocyst growth)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0035327"|go:"GO:0042169"(SH2 domain binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:2000653"(regulation of genetic imprinting)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031101|mint:Q6PD62|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|dip:DIP-31693N refseq:NP_079510.1|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9GZS3|rcsb pdb:3OW8|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-429958|reactome:R-HSA-674695|reactome:R-HSA-75955|ensembl:ENSG00000140395(gene)|ensembl:ENST00000267973(transcript)|ensembl:ENST00000558311(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0055087"(Ski complex)|reactome:R-HSA-8866654|refseq:XP_011520396.1|refseq:NP_001290176.1|refseq:NP_001290177.1|dip:DIP-36672N - - - figure legend:ST2|comment:"Two-step purifications decrease the number of nonspecific binders while preserving specific ones (Table S2)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/17 rogid:zEFAxq/VxkK8za6qsK0gcU+EU8o9606 rogid:yVcjv2BXXr3VFSR7OcJ/1u9L6gw9606 rigid:hXXhlT4Lb3VAQl1O/QlawlROfSE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6PD62 uniprotkb:Q6P1J9 intact:EBI-1019583|uniprotkb:Q15015|uniprotkb:D3DQV8|ensembl:ENSP00000355013 intact:EBI-930143|uniprotkb:A6NLZ8|uniprotkb:Q6PK51|uniprotkb:Q96A07|uniprotkb:Q9H245|uniprotkb:Q9H5L7|uniprotkb:B2RBR2|ensembl:ENSP00000356405 psi-mi:ctr9_human(display_long)|uniprotkb:CTR9(gene name)|psi-mi:CTR9(display_short)|uniprotkb:KIAA0155(gene name synonym)|uniprotkb:SH2BP1(gene name synonym)|uniprotkb:SH2 domain-binding protein 1(gene name synonym) psi-mi:cdc73_human(display_long)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:C1orf28(gene name synonym)|uniprotkb:HRPT2(gene name synonym)|uniprotkb:Cell division cycle protein 73 homolog(gene name synonym)|uniprotkb:Hyperparathyroidism 2 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25471055|imex:IM-26985-303 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055448.1|ensembl:ENSG00000198730(gene)|ensembl:ENST00000361367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001826"(inner cell mass cell differentiation)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001832"(blastocyst growth)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0035327"|go:"GO:0042169"(SH2 domain binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:2000653"(regulation of genetic imprinting)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031101|mint:Q6PD62|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|dip:DIP-31693N refseq:NP_078805.3|dip:DIP-37884N|ensembl:ENSG00000134371(gene)|ensembl:ENST00000367435(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0031648"(protein destabilization)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR032041|interpro:IPR038103|mint:Q6P1J9|rcsb pdb:5YDE|rcsb pdb:5YDF|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-201722|reactome:R-HSA-5632684|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654 - - - figure legend:ST2|comment:"Two-step purifications decrease the number of nonspecific binders while preserving specific ones (Table S2)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/17 rogid:zEFAxq/VxkK8za6qsK0gcU+EU8o9606 rogid:nuJ2kK0petj8iBr17I2BQzxcVmE9606 rigid:hXXhlT4Lb3VAQl1O/QlawlROfSE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6PD62 uniprotkb:Q8N7H5 intact:EBI-1019583|uniprotkb:Q15015|uniprotkb:D3DQV8|ensembl:ENSP00000355013 intact:EBI-2607770|uniprotkb:O75239|uniprotkb:Q9H166|uniprotkb:Q9NUU9|ensembl:ENSP00000221265|uniprotkb:M0QX35 psi-mi:ctr9_human(display_long)|uniprotkb:CTR9(gene name)|psi-mi:CTR9(display_short)|uniprotkb:KIAA0155(gene name synonym)|uniprotkb:SH2BP1(gene name synonym)|uniprotkb:SH2 domain-binding protein 1(gene name synonym) psi-mi:paf1_human(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:PD2(gene name synonym)|uniprotkb:Pancreatic differentiation protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25471055|imex:IM-26985-303 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055448.1|ensembl:ENSG00000198730(gene)|ensembl:ENST00000361367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001826"(inner cell mass cell differentiation)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001832"(blastocyst growth)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0035327"|go:"GO:0042169"(SH2 domain binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:2000653"(regulation of genetic imprinting)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031101|mint:Q6PD62|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|dip:DIP-31693N refseq:NP_061961.2|ensembl:ENSG00000006712(gene)|ensembl:ENST00000221265(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030054"(cell junction)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|mint:Q8N7H5|rcsb pdb:4M6T|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|refseq:NP_001243755.1|dip:DIP-48673N - - - figure legend:ST2|comment:"Two-step purifications decrease the number of nonspecific binders while preserving specific ones (Table S2)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/17 rogid:zEFAxq/VxkK8za6qsK0gcU+EU8o9606 rogid:5Bf9gSdxgaufI30DVL8QAyVLqNk9606 rigid:hXXhlT4Lb3VAQl1O/QlawlROfSE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P29375 uniprotkb:Q2LD37 intact:EBI-1560836|uniprotkb:Q86XZ1|uniprotkb:A8MV76|uniprotkb:Q4LE72|ensembl:ENSP00000382688 intact:EBI-2683809|uniprotkb:Q9UPP3|uniprotkb:Q8WVD8|uniprotkb:Q9NTI4|uniprotkb:Q9P2H6|uniprotkb:Q4W598|uniprotkb:Q86XA5|uniprotkb:Q5CZA9|uniprotkb:Q9H742|uniprotkb:Q9NTC3|uniprotkb:Q6ZS70|uniprotkb:Q9NT48|uniprotkb:Q6ZV75|ensembl:ENSP00000264501|ensembl:ENSP00000373390 psi-mi:kdm5a_human(display_long)|uniprotkb:Jumonji/ARID domain-containing protein 1A(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2(gene name synonym)|uniprotkb:KDM5A(gene name)|psi-mi:KDM5A(display_short)|uniprotkb:RBBP2(gene name synonym)|uniprotkb:RBP2(gene name synonym)|uniprotkb:JARID1A(gene name synonym)|uniprotkb:Histone demethylase JARID1A(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5A"(gene name synonym) psi-mi:k1109_human(display_long)|uniprotkb:FSA(gene name synonym)|uniprotkb:KIAA1371(gene name synonym)|uniprotkb:Fragile site-associated protein(gene name synonym)|uniprotkb:KIAA1109(gene name)|psi-mi:KIAA1109(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25471065|imex:IM-26985-581 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036068.1|dip:DIP-472N|ensembl:ENSG00000073614(gene)|ensembl:ENST00000399788(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051213"(dioxygenase activity)|go:"GO:1901726"(negative regulation of histone deacetylase activity)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:P29375|rcsb pdb:2JXJ|rcsb pdb:2KGG|rcsb pdb:2KGI|rcsb pdb:3GL6|rcsb pdb:5C11|rcsb pdb:5CEH|rcsb pdb:5E6H|rcsb pdb:5ISL|rcsb pdb:5IVB|rcsb pdb:5IVC|rcsb pdb:5IVE|rcsb pdb:5IVF|rcsb pdb:5IVJ|rcsb pdb:5IVV|rcsb pdb:5IVY|rcsb pdb:5IW0|rcsb pdb:5IWF|rcsb pdb:5K4L|rcsb pdb:5V9P|rcsb pdb:5V9T|rcsb pdb:6BGU|rcsb pdb:6BGV|rcsb pdb:6BGW|rcsb pdb:6BGX|rcsb pdb:6BGY|rcsb pdb:6BGZ|rcsb pdb:6BH0|rcsb pdb:6BH1|rcsb pdb:6BH2|rcsb pdb:6BH3|rcsb pdb:6BH4|rcsb pdb:6BH5|rcsb pdb:6DQ4|rcsb pdb:6DQ5|rcsb pdb:6DQ6|rcsb pdb:6DQ7|rcsb pdb:6DQ8|rcsb pdb:6DQ9|rcsb pdb:6DQA|rcsb pdb:6DQB|rcsb pdb:6DQC|rcsb pdb:6DQD|rcsb pdb:6DQE|rcsb pdb:6DQF|rcsb pdb:7KLO|rcsb pdb:7KLR|reactome:R-HSA-3214842 refseq:NP_056127.2|refseq:XP_005263344.1|ensembl:ENSG00000138688(gene)|ensembl:ENST00000264501(transcript)|ensembl:ENST00000388738(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0005634"(nucleus)|go:"GO:0006909"(phagocytosis)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030856"(regulation of epithelial cell differentiation)|go:"GO:0032456"(endocytic recycling)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0098793"(presynapse)|interpro:IPR018863|interpro:IPR033616|mint:Q2LD37|refseq:XP_006714407.1 - - - figure legend:ST2|comment:"Two-step purifications decrease the number of nonspecific binders while preserving specific ones (Table S2)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/17 rogid:F6XYSW2/X7BvtDjU/1wBBa8jhTM9606 rogid:JPb6Yq3X0tdaCFapYIt14WacfpI9606 rigid:aw8+TD4mg9SJy7l7Ch9Mb5eZgkI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P29375 uniprotkb:Q9UBU8 intact:EBI-1560836|uniprotkb:Q86XZ1|uniprotkb:A8MV76|uniprotkb:Q4LE72|ensembl:ENSP00000382688 intact:EBI-399246|uniprotkb:O95899|uniprotkb:Q5QTS1|uniprotkb:Q6NVX8|uniprotkb:Q86YT7|uniprotkb:Q9HBP6|uniprotkb:Q9NSW5|uniprotkb:B4DKN6|uniprotkb:D3DW88|ensembl:ENSP00000331310|uniprotkb:B7Z6R1 psi-mi:kdm5a_human(display_long)|uniprotkb:Jumonji/ARID domain-containing protein 1A(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2(gene name synonym)|uniprotkb:KDM5A(gene name)|psi-mi:KDM5A(display_short)|uniprotkb:RBBP2(gene name synonym)|uniprotkb:RBP2(gene name synonym)|uniprotkb:JARID1A(gene name synonym)|uniprotkb:Histone demethylase JARID1A(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5A"(gene name synonym) psi-mi:mo4l1_human(display_long)|uniprotkb:HSPC008(orf name)|uniprotkb:HSPC061(orf name)|uniprotkb:PP368(orf name)|uniprotkb:MORF4L1(gene name)|psi-mi:MORF4L1(display_short)|uniprotkb:MRG15(gene name synonym)|uniprotkb:MORF-related gene 15 protein(gene name synonym)|uniprotkb:Transcription factor-like protein MRG15(gene name synonym)|uniprotkb:Protein MSL3-1(gene name synonym)|uniprotkb:FWP006(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25471065|imex:IM-26985-581 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036068.1|dip:DIP-472N|ensembl:ENSG00000073614(gene)|ensembl:ENST00000399788(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051213"(dioxygenase activity)|go:"GO:1901726"(negative regulation of histone deacetylase activity)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:P29375|rcsb pdb:2JXJ|rcsb pdb:2KGG|rcsb pdb:2KGI|rcsb pdb:3GL6|rcsb pdb:5C11|rcsb pdb:5CEH|rcsb pdb:5E6H|rcsb pdb:5ISL|rcsb pdb:5IVB|rcsb pdb:5IVC|rcsb pdb:5IVE|rcsb pdb:5IVF|rcsb pdb:5IVJ|rcsb pdb:5IVV|rcsb pdb:5IVY|rcsb pdb:5IW0|rcsb pdb:5IWF|rcsb pdb:5K4L|rcsb pdb:5V9P|rcsb pdb:5V9T|rcsb pdb:6BGU|rcsb pdb:6BGV|rcsb pdb:6BGW|rcsb pdb:6BGX|rcsb pdb:6BGY|rcsb pdb:6BGZ|rcsb pdb:6BH0|rcsb pdb:6BH1|rcsb pdb:6BH2|rcsb pdb:6BH3|rcsb pdb:6BH4|rcsb pdb:6BH5|rcsb pdb:6DQ4|rcsb pdb:6DQ5|rcsb pdb:6DQ6|rcsb pdb:6DQ7|rcsb pdb:6DQ8|rcsb pdb:6DQ9|rcsb pdb:6DQA|rcsb pdb:6DQB|rcsb pdb:6DQC|rcsb pdb:6DQD|rcsb pdb:6DQE|rcsb pdb:6DQF|rcsb pdb:7KLO|rcsb pdb:7KLR|reactome:R-HSA-3214842 refseq:NP_006782.1|refseq:NP_996670.1|dip:DIP-29017N|refseq:NP_001252532.1|refseq:NP_001252533.1|refseq:NP_001252534.1|ensembl:ENSG00000185787(gene)|ensembl:ENST00000331268(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0016573"(histone acetylation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR008676(MRG)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR026541|interpro:IPR038011|interpro:IPR038217|mint:Q9UBU8|rcsb pdb:2AQL|rcsb pdb:2EFI|rcsb pdb:2F5J|rcsb pdb:2F5K|rcsb pdb:2LKM|rcsb pdb:2N1D|rcsb pdb:6AGO|rcsb pdb:6INE|reactome:R-HSA-3214847 - - - figure legend:ST2|comment:"Two-step purifications decrease the number of nonspecific binders while preserving specific ones (Table S2)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/17 rogid:F6XYSW2/X7BvtDjU/1wBBa8jhTM9606 rogid:28GQifqUMxwR32cneTXH+lpW4gM9606 rigid:aw8+TD4mg9SJy7l7Ch9Mb5eZgkI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P29375 uniprotkb:Q09028 intact:EBI-1560836|uniprotkb:Q86XZ1|uniprotkb:A8MV76|uniprotkb:Q4LE72|ensembl:ENSP00000382688 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 psi-mi:kdm5a_human(display_long)|uniprotkb:Jumonji/ARID domain-containing protein 1A(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2(gene name synonym)|uniprotkb:KDM5A(gene name)|psi-mi:KDM5A(display_short)|uniprotkb:RBBP2(gene name synonym)|uniprotkb:RBP2(gene name synonym)|uniprotkb:JARID1A(gene name synonym)|uniprotkb:Histone demethylase JARID1A(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5A"(gene name synonym) psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25471065|imex:IM-26985-581 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036068.1|dip:DIP-472N|ensembl:ENSG00000073614(gene)|ensembl:ENST00000399788(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051213"(dioxygenase activity)|go:"GO:1901726"(negative regulation of histone deacetylase activity)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:P29375|rcsb pdb:2JXJ|rcsb pdb:2KGG|rcsb pdb:2KGI|rcsb pdb:3GL6|rcsb pdb:5C11|rcsb pdb:5CEH|rcsb pdb:5E6H|rcsb pdb:5ISL|rcsb pdb:5IVB|rcsb pdb:5IVC|rcsb pdb:5IVE|rcsb pdb:5IVF|rcsb pdb:5IVJ|rcsb pdb:5IVV|rcsb pdb:5IVY|rcsb pdb:5IW0|rcsb pdb:5IWF|rcsb pdb:5K4L|rcsb pdb:5V9P|rcsb pdb:5V9T|rcsb pdb:6BGU|rcsb pdb:6BGV|rcsb pdb:6BGW|rcsb pdb:6BGX|rcsb pdb:6BGY|rcsb pdb:6BGZ|rcsb pdb:6BH0|rcsb pdb:6BH1|rcsb pdb:6BH2|rcsb pdb:6BH3|rcsb pdb:6BH4|rcsb pdb:6BH5|rcsb pdb:6DQ4|rcsb pdb:6DQ5|rcsb pdb:6DQ6|rcsb pdb:6DQ7|rcsb pdb:6DQ8|rcsb pdb:6DQ9|rcsb pdb:6DQA|rcsb pdb:6DQB|rcsb pdb:6DQC|rcsb pdb:6DQD|rcsb pdb:6DQE|rcsb pdb:6DQF|rcsb pdb:7KLO|rcsb pdb:7KLR|reactome:R-HSA-3214842 ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N - - - figure legend:ST2|comment:"Two-step purifications decrease the number of nonspecific binders while preserving specific ones (Table S2)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/17 rogid:F6XYSW2/X7BvtDjU/1wBBa8jhTM9606 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rigid:aw8+TD4mg9SJy7l7Ch9Mb5eZgkI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P29375 uniprotkb:O75182 intact:EBI-1560836|uniprotkb:Q86XZ1|uniprotkb:A8MV76|uniprotkb:Q4LE72|ensembl:ENSP00000382688 intact:EBI-540462|uniprotkb:Q68GC2|uniprotkb:Q6P4B8|uniprotkb:Q8TB34|uniprotkb:Q9BSC8|uniprotkb:Q2NL91|ensembl:ENSP00000369131 psi-mi:kdm5a_human(display_long)|uniprotkb:Jumonji/ARID domain-containing protein 1A(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2(gene name synonym)|uniprotkb:KDM5A(gene name)|psi-mi:KDM5A(display_short)|uniprotkb:RBBP2(gene name synonym)|uniprotkb:RBP2(gene name synonym)|uniprotkb:JARID1A(gene name synonym)|uniprotkb:Histone demethylase JARID1A(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5A"(gene name synonym) psi-mi:sin3b_human(display_long)|uniprotkb:Transcriptional corepressor Sin3b(gene name synonym)|uniprotkb:Histone deacetylase complex subunit Sin3b(gene name synonym)|uniprotkb:SIN3B(gene name)|psi-mi:SIN3B(display_short)|uniprotkb:KIAA0700(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25471065|imex:IM-26985-581 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036068.1|dip:DIP-472N|ensembl:ENSG00000073614(gene)|ensembl:ENST00000399788(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051213"(dioxygenase activity)|go:"GO:1901726"(negative regulation of histone deacetylase activity)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:P29375|rcsb pdb:2JXJ|rcsb pdb:2KGG|rcsb pdb:2KGI|rcsb pdb:3GL6|rcsb pdb:5C11|rcsb pdb:5CEH|rcsb pdb:5E6H|rcsb pdb:5ISL|rcsb pdb:5IVB|rcsb pdb:5IVC|rcsb pdb:5IVE|rcsb pdb:5IVF|rcsb pdb:5IVJ|rcsb pdb:5IVV|rcsb pdb:5IVY|rcsb pdb:5IW0|rcsb pdb:5IWF|rcsb pdb:5K4L|rcsb pdb:5V9P|rcsb pdb:5V9T|rcsb pdb:6BGU|rcsb pdb:6BGV|rcsb pdb:6BGW|rcsb pdb:6BGX|rcsb pdb:6BGY|rcsb pdb:6BGZ|rcsb pdb:6BH0|rcsb pdb:6BH1|rcsb pdb:6BH2|rcsb pdb:6BH3|rcsb pdb:6BH4|rcsb pdb:6BH5|rcsb pdb:6DQ4|rcsb pdb:6DQ5|rcsb pdb:6DQ6|rcsb pdb:6DQ7|rcsb pdb:6DQ8|rcsb pdb:6DQ9|rcsb pdb:6DQA|rcsb pdb:6DQB|rcsb pdb:6DQC|rcsb pdb:6DQD|rcsb pdb:6DQE|rcsb pdb:6DQF|rcsb pdb:7KLO|rcsb pdb:7KLR|reactome:R-HSA-3214842 refseq:NP_056075.1|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0030849"(autosome)|interpro:IPR003822(Paired amphipathic helix)|interpro:IPR013194(Histone deacetylase interacting)|interpro:IPR031693|go:"GO:0003682"(chromatin binding)|interpro:IPR036600|interpro:IPR039774|mint:O75182|reactome:R-HSA-400206|reactome:R-HSA-427413|reactome:R-HSA-8936459|reactome:R-HSA-9707564|ensembl:ENSG00000127511(gene)|ensembl:ENST00000379803(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000805"(X chromosome)|go:"GO:0000806"(Y chromosome)|go:"GO:0001741"(XY body)|refseq:NP_001284524.1|refseq:NP_001284526.1 - - - figure legend:ST2|comment:"Two-step purifications decrease the number of nonspecific binders while preserving specific ones (Table S2)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/17 rogid:F6XYSW2/X7BvtDjU/1wBBa8jhTM9606 rogid:ney2nq8TMh2sFxskgXr+NgNCl349606 rigid:aw8+TD4mg9SJy7l7Ch9Mb5eZgkI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P29375 uniprotkb:Q8WUU5 intact:EBI-1560836|uniprotkb:Q86XZ1|uniprotkb:A8MV76|uniprotkb:Q4LE72|ensembl:ENSP00000382688 intact:EBI-3916882|uniprotkb:D6W5Q5|uniprotkb:Q9H689|uniprotkb:Q8N5Y5|uniprotkb:Q99995|uniprotkb:B2RE37|ensembl:ENSP00000287957 psi-mi:kdm5a_human(display_long)|uniprotkb:Jumonji/ARID domain-containing protein 1A(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2(gene name synonym)|uniprotkb:KDM5A(gene name)|psi-mi:KDM5A(display_short)|uniprotkb:RBBP2(gene name synonym)|uniprotkb:RBP2(gene name synonym)|uniprotkb:JARID1A(gene name synonym)|uniprotkb:Histone demethylase JARID1A(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5A"(gene name synonym) psi-mi:gatd1_human(display_long)|uniprotkb:GATAD1(gene name)|psi-mi:GATAD1(display_short)|uniprotkb:ODAG(gene name synonym)|uniprotkb:Ocular development-associated gene protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25471065|imex:IM-26985-581 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036068.1|dip:DIP-472N|ensembl:ENSG00000073614(gene)|ensembl:ENST00000399788(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051213"(dioxygenase activity)|go:"GO:1901726"(negative regulation of histone deacetylase activity)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:P29375|rcsb pdb:2JXJ|rcsb pdb:2KGG|rcsb pdb:2KGI|rcsb pdb:3GL6|rcsb pdb:5C11|rcsb pdb:5CEH|rcsb pdb:5E6H|rcsb pdb:5ISL|rcsb pdb:5IVB|rcsb pdb:5IVC|rcsb pdb:5IVE|rcsb pdb:5IVF|rcsb pdb:5IVJ|rcsb pdb:5IVV|rcsb pdb:5IVY|rcsb pdb:5IW0|rcsb pdb:5IWF|rcsb pdb:5K4L|rcsb pdb:5V9P|rcsb pdb:5V9T|rcsb pdb:6BGU|rcsb pdb:6BGV|rcsb pdb:6BGW|rcsb pdb:6BGX|rcsb pdb:6BGY|rcsb pdb:6BGZ|rcsb pdb:6BH0|rcsb pdb:6BH1|rcsb pdb:6BH2|rcsb pdb:6BH3|rcsb pdb:6BH4|rcsb pdb:6BH5|rcsb pdb:6DQ4|rcsb pdb:6DQ5|rcsb pdb:6DQ6|rcsb pdb:6DQ7|rcsb pdb:6DQ8|rcsb pdb:6DQ9|rcsb pdb:6DQA|rcsb pdb:6DQB|rcsb pdb:6DQC|rcsb pdb:6DQD|rcsb pdb:6DQE|rcsb pdb:6DQF|rcsb pdb:7KLO|rcsb pdb:7KLR|reactome:R-HSA-3214842 refseq:NP_066990.3|ensembl:ENSG00000157259(gene)|ensembl:ENST00000287957(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR039050|mint:Q8WUU5 - - - figure legend:ST2|comment:"Two-step purifications decrease the number of nonspecific binders while preserving specific ones (Table S2)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/17 rogid:F6XYSW2/X7BvtDjU/1wBBa8jhTM9606 rogid:mwq5yOlZTelKYR0VGr822k9K0Nk9606 rigid:aw8+TD4mg9SJy7l7Ch9Mb5eZgkI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P29375 uniprotkb:Q7Z589 intact:EBI-1560836|uniprotkb:Q86XZ1|uniprotkb:A8MV76|uniprotkb:Q4LE72|ensembl:ENSP00000382688 intact:EBI-6598631|ensembl:ENSP00000334130|ensembl:ENSP00000432327|uniprotkb:Q4G109|uniprotkb:Q8NBU6|uniprotkb:Q8TE50|uniprotkb:Q9H8I9|uniprotkb:Q9NRH0|uniprotkb:B7ZKU0|uniprotkb:B7ZKT8|uniprotkb:B7ZKU2|uniprotkb:Q17RM7 psi-mi:kdm5a_human(display_long)|uniprotkb:Jumonji/ARID domain-containing protein 1A(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2(gene name synonym)|uniprotkb:KDM5A(gene name)|psi-mi:KDM5A(display_short)|uniprotkb:RBBP2(gene name synonym)|uniprotkb:RBP2(gene name synonym)|uniprotkb:JARID1A(gene name synonym)|uniprotkb:Histone demethylase JARID1A(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5A"(gene name synonym) psi-mi:emsy_human(display_long)|uniprotkb:EMSY(gene name)|psi-mi:EMSY(display_short)|uniprotkb:C11orf30(gene name synonym)|uniprotkb:GL002(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25471065|imex:IM-26985-581 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036068.1|dip:DIP-472N|ensembl:ENSG00000073614(gene)|ensembl:ENST00000399788(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051213"(dioxygenase activity)|go:"GO:1901726"(negative regulation of histone deacetylase activity)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:P29375|rcsb pdb:2JXJ|rcsb pdb:2KGG|rcsb pdb:2KGI|rcsb pdb:3GL6|rcsb pdb:5C11|rcsb pdb:5CEH|rcsb pdb:5E6H|rcsb pdb:5ISL|rcsb pdb:5IVB|rcsb pdb:5IVC|rcsb pdb:5IVE|rcsb pdb:5IVF|rcsb pdb:5IVJ|rcsb pdb:5IVV|rcsb pdb:5IVY|rcsb pdb:5IW0|rcsb pdb:5IWF|rcsb pdb:5K4L|rcsb pdb:5V9P|rcsb pdb:5V9T|rcsb pdb:6BGU|rcsb pdb:6BGV|rcsb pdb:6BGW|rcsb pdb:6BGX|rcsb pdb:6BGY|rcsb pdb:6BGZ|rcsb pdb:6BH0|rcsb pdb:6BH1|rcsb pdb:6BH2|rcsb pdb:6BH3|rcsb pdb:6BH4|rcsb pdb:6BH5|rcsb pdb:6DQ4|rcsb pdb:6DQ5|rcsb pdb:6DQ6|rcsb pdb:6DQ7|rcsb pdb:6DQ8|rcsb pdb:6DQ9|rcsb pdb:6DQA|rcsb pdb:6DQB|rcsb pdb:6DQC|rcsb pdb:6DQD|rcsb pdb:6DQE|rcsb pdb:6DQF|rcsb pdb:7KLO|rcsb pdb:7KLR|reactome:R-HSA-3214842 refseq:NP_001287871.1|refseq:NP_001287872.1|refseq:NP_001287873.1|ensembl:ENST00000334736(transcript)|ensembl:ENST00000529032(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0042802"(identical protein binding)|interpro:IPR005491(ENT)|interpro:IPR033482|interpro:IPR036142|mint:Q7Z589|rcsb pdb:1UTU|ensembl:ENSG00000158636(gene)|rcsb pdb:1UZ3|rcsb pdb:2FMM|refseq:NP_064578.2|ensembl:ENSP00000433634|ensembl:ENST00000533988|ensembl:ENSP00000434665|ensembl:ENSP00000334130|ensembl:ENST00000524767|ensembl:ENSP00000433205|ensembl:ENST00000525038|ensembl:ENSP00000436968|ensembl:ENST00000525919|ensembl:ENSP00000432010|ensembl:ENSP00000432327|ensembl:ENST00000533248|dip:DIP-29099N - - - figure legend:ST2|comment:"Two-step purifications decrease the number of nonspecific binders while preserving specific ones (Table S2)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/17 rogid:F6XYSW2/X7BvtDjU/1wBBa8jhTM9606 rogid:AlagiKsle+RG5HUine4x/QddsJc9606 rigid:aw8+TD4mg9SJy7l7Ch9Mb5eZgkI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P29375 uniprotkb:Q96QT6 intact:EBI-1560836|uniprotkb:Q86XZ1|uniprotkb:A8MV76|uniprotkb:Q4LE72|ensembl:ENSP00000382688 intact:EBI-2803760|uniprotkb:Q9BV34|uniprotkb:Q9P205|uniprotkb:Q6ZML2|uniprotkb:Q0VAI5|uniprotkb:Q9H7U9|ensembl:ENSP00000329933|uniprotkb:Q2TAK2 psi-mi:kdm5a_human(display_long)|uniprotkb:Jumonji/ARID domain-containing protein 1A(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2(gene name synonym)|uniprotkb:KDM5A(gene name)|psi-mi:KDM5A(display_short)|uniprotkb:RBBP2(gene name synonym)|uniprotkb:RBP2(gene name synonym)|uniprotkb:JARID1A(gene name synonym)|uniprotkb:Histone demethylase JARID1A(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5A"(gene name synonym) psi-mi:phf12_human(display_long)|uniprotkb:KIAA1523(gene name synonym)|uniprotkb:PHD factor 1(gene name synonym)|uniprotkb:PHF12(gene name)|psi-mi:PHF12(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25471065|imex:IM-26985-581 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036068.1|dip:DIP-472N|ensembl:ENSG00000073614(gene)|ensembl:ENST00000399788(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051213"(dioxygenase activity)|go:"GO:1901726"(negative regulation of histone deacetylase activity)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:P29375|rcsb pdb:2JXJ|rcsb pdb:2KGG|rcsb pdb:2KGI|rcsb pdb:3GL6|rcsb pdb:5C11|rcsb pdb:5CEH|rcsb pdb:5E6H|rcsb pdb:5ISL|rcsb pdb:5IVB|rcsb pdb:5IVC|rcsb pdb:5IVE|rcsb pdb:5IVF|rcsb pdb:5IVJ|rcsb pdb:5IVV|rcsb pdb:5IVY|rcsb pdb:5IW0|rcsb pdb:5IWF|rcsb pdb:5K4L|rcsb pdb:5V9P|rcsb pdb:5V9T|rcsb pdb:6BGU|rcsb pdb:6BGV|rcsb pdb:6BGW|rcsb pdb:6BGX|rcsb pdb:6BGY|rcsb pdb:6BGZ|rcsb pdb:6BH0|rcsb pdb:6BH1|rcsb pdb:6BH2|rcsb pdb:6BH3|rcsb pdb:6BH4|rcsb pdb:6BH5|rcsb pdb:6DQ4|rcsb pdb:6DQ5|rcsb pdb:6DQ6|rcsb pdb:6DQ7|rcsb pdb:6DQ8|rcsb pdb:6DQ9|rcsb pdb:6DQA|rcsb pdb:6DQB|rcsb pdb:6DQC|rcsb pdb:6DQD|rcsb pdb:6DQE|rcsb pdb:6DQF|rcsb pdb:7KLO|rcsb pdb:7KLR|reactome:R-HSA-3214842 refseq:NP_001028733.1|refseq:NP_065940.1|ensembl:ENSG00000109118(gene)|ensembl:ENST00000332830(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016580"(Sin3 complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070822"(Sin3-type complex)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR031966|interpro:IPR038098|interpro:IPR042163|mint:Q96QT6|rcsb pdb:2L9S|rcsb pdb:2LKM|refseq:NP_001277060.1|dip:DIP-59632N - - - figure legend:ST2|comment:"Two-step purifications decrease the number of nonspecific binders while preserving specific ones (Table S2)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/17 rogid:F6XYSW2/X7BvtDjU/1wBBa8jhTM9606 rogid:PSctZ9CGOcztlg6VdcB1jkIOhjo9606 rigid:aw8+TD4mg9SJy7l7Ch9Mb5eZgkI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92667 uniprotkb:P17612 intact:EBI-2119593|uniprotkb:Q13320|uniprotkb:Q9BW14|uniprotkb:A8K8Q1|uniprotkb:D3DTZ0|ensembl:ENSP00000337736|ensembl:ENSP00000443139|ensembl:ENSP00000459895|ensembl:ENSP00000459968|ensembl:ENSP00000478212 intact:EBI-476586|uniprotkb:Q32P54|uniprotkb:Q9H2Y0|uniprotkb:Q9NRB4|uniprotkb:Q9NRH9|ensembl:ENSP00000309591|ensembl:ENSP00000499940 psi-mi:akap1_human(display_long)|uniprotkb:AKAP1(gene name)|psi-mi:AKAP1(display_short)|uniprotkb:AKAP149(gene name synonym)|uniprotkb:PRKA1(gene name synonym)|uniprotkb:Protein kinase A-anchoring protein 1(gene name synonym)|uniprotkb:A-kinase anchor protein 149 kDa(gene name synonym)|uniprotkb:Dual specificity A-kinase-anchoring protein 1(gene name synonym)|uniprotkb:Spermatid A-kinase anchor protein 84(gene name synonym) psi-mi:kapca_human(display_long)|uniprotkb:PRKACA(gene name)|psi-mi:PRKACA(display_short)|uniprotkb:PKACA(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25475929|imex:IM-26985-225 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880678.1|refseq:XP_016880679.1|refseq:XP_016880680.1|refseq:NP_001229831.1|refseq:NP_001229832.1|refseq:NP_003479.1|refseq:XP_005257764.1|refseq:XP_005257766.1|ensembl:ENSG00000121057(gene)|ensembl:ENST00000337714(transcript)|ensembl:ENST00000539273(transcript)|ensembl:ENST00000571629(transcript)|ensembl:ENST00000572557(transcript)|ensembl:ENST00000621116(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR002999(Tudor)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR035437|interpro:IPR036612|mint:Q92667|reactome:R-HSA-8949215|reactome:R-HSA-983231 refseq:NP_002721.1|refseq:NP_997401.1|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016607"(nuclear speck)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|ensembl:ENSG00000072062(gene)|ensembl:ENSG00000288516(gene)|ensembl:ENST00000308677(transcript)|ensembl:ENST00000673550(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001843"(neural tube closure)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003091"(renal water homeostasis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0030145"(manganese ion binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034704"(calcium channel complex)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0036126"(sperm flagellum)|go:"GO:0043197"(dendritic spine)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0048240"(sperm capacitation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055117"(regulation of cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071374"(cellular response to parathyroid hormone stimulus)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097546"(ciliary base)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|go:"GO:0046827"(positive regulation of protein export from nucleus)|rcsb pdb:5IZJ|rcsb pdb:5J5X|rcsb pdb:5N23|rcsb pdb:5UZK|rcsb pdb:6BYR|rcsb pdb:6BYS|rcsb pdb:6C0U|rcsb pdb:6FRX|rcsb pdb:6NO7|rcsb pdb:6QJ7|rcsb pdb:6WJF|rcsb pdb:6WJG|reactome:R-HSA-111931|reactome:R-HSA-163358|reactome:R-HSA-163560|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-2565942|reactome:R-HSA-380259|rcsb pdb:3MVJ|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3NX8|interpro:IPR044109|rcsb pdb:3OOG|rcsb pdb:3OVV|rcsb pdb:3OWP|rcsb pdb:3OXT|rcsb pdb:3P0M|mint:P17612|rcsb pdb:3POO|rcsb pdb:3VQH|rcsb pdb:4AE6|rcsb pdb:2GU8|rcsb pdb:4AE9|rcsb pdb:4UJ1|rcsb pdb:4UJ2|rcsb pdb:3AGL|rcsb pdb:3AGM|rcsb pdb:3AMA|rcsb pdb:3AMB|rcsb pdb:4UJ9|rcsb pdb:4UJA|rcsb pdb:4UJB|rcsb pdb:4WB5|rcsb pdb:4WB6|rcsb pdb:4WB7|rcsb pdb:3L9L|rcsb pdb:3L9M|rcsb pdb:3L9N|rcsb pdb:4WB8|rcsb pdb:5BX6|rcsb pdb:5BX7|rcsb pdb:5IZF|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-381676|reactome:R-HSA-392517|reactome:R-HSA-422356|reactome:R-HSA-432040|reactome:R-HSA-4420097|reactome:R-HSA-442720|reactome:R-HSA-512988|reactome:R-HSA-5578775|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5610787|reactome:R-HSA-5620912|reactome:R-HSA-5621575|reactome:R-HSA-5687128|reactome:R-HSA-8853659|reactome:R-HSA-8854518|reactome:R-HSA-380320|reactome:R-HSA-8963896|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9634600|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|reactome:R-HSA-9010642|refseq:NP_001291278.1|dip:DIP-33878N - - comment:"author score: 43" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8HzwuoBdBWw+LZKg6WpYxMKnfYE9606 rogid:7yhAi67qjSKPIff2dwqjScPXEYM9606 rigid:Djjt3Q24jgkzG4WOluz5tu4rtRs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92667 uniprotkb:P02679 intact:EBI-2119593|uniprotkb:Q13320|uniprotkb:Q9BW14|uniprotkb:A8K8Q1|uniprotkb:D3DTZ0|ensembl:ENSP00000337736|ensembl:ENSP00000443139|ensembl:ENSP00000459895|ensembl:ENSP00000459968|ensembl:ENSP00000478212 intact:EBI-1034422|uniprotkb:P04469|uniprotkb:P04470|uniprotkb:Q96A14|uniprotkb:Q96KJ3|uniprotkb:A8K057|uniprotkb:Q53Y18|uniprotkb:Q9UC62|uniprotkb:Q9UC63|uniprotkb:Q9UCF3|ensembl:ENSP00000336829 psi-mi:akap1_human(display_long)|uniprotkb:AKAP1(gene name)|psi-mi:AKAP1(display_short)|uniprotkb:AKAP149(gene name synonym)|uniprotkb:PRKA1(gene name synonym)|uniprotkb:Protein kinase A-anchoring protein 1(gene name synonym)|uniprotkb:A-kinase anchor protein 149 kDa(gene name synonym)|uniprotkb:Dual specificity A-kinase-anchoring protein 1(gene name synonym)|uniprotkb:Spermatid A-kinase anchor protein 84(gene name synonym) psi-mi:fibg_human(display_long)|uniprotkb:FGG(gene name)|psi-mi:FGG(display_short)|uniprotkb:PRO2061(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25475929|imex:IM-26985-225 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880678.1|refseq:XP_016880679.1|refseq:XP_016880680.1|refseq:NP_001229831.1|refseq:NP_001229832.1|refseq:NP_003479.1|refseq:XP_005257764.1|refseq:XP_005257766.1|ensembl:ENSG00000121057(gene)|ensembl:ENST00000337714(transcript)|ensembl:ENST00000539273(transcript)|ensembl:ENST00000571629(transcript)|ensembl:ENST00000572557(transcript)|ensembl:ENST00000621116(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR002999(Tudor)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR035437|interpro:IPR036612|mint:Q92667|reactome:R-HSA-8949215|reactome:R-HSA-983231 refseq:NP_000500.2|refseq:NP_068656.2|ensembl:ENSG00000171557(gene)|ensembl:ENST00000336098(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0009306"(protein secretion)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031639"(plasminogen activation)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034622"|go:"GO:0036345"(platelet maturation)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051258"(protein polymerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0090277"(positive regulation of peptide hormone secretion)|go:"GO:0090331"(negative regulation of platelet aggregation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR012290(Fibrinogen, alpha/beta/gamma chain, coiled coil)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|interpro:IPR037581|mint:P02679|rcsb pdb:1DUG|rcsb pdb:1FIB|rcsb pdb:1FIC|rcsb pdb:1FID|rcsb pdb:1FZA|go:"GO:0070527"(platelet aggregation)|rcsb pdb:1FZB|rcsb pdb:1FZC|rcsb pdb:1FZE|rcsb pdb:1FZF|rcsb pdb:1FZG|rcsb pdb:1LT9|rcsb pdb:1LTJ|rcsb pdb:1N86|rcsb pdb:1N8E|rcsb pdb:1RE3|rcsb pdb:1RE4|rcsb pdb:1RF0|rcsb pdb:1RF1|rcsb pdb:2A45|rcsb pdb:2FFD|rcsb pdb:2FIB|rcsb pdb:2H43|rcsb pdb:2HLO|rcsb pdb:2HOD|rcsb pdb:2HPC|rcsb pdb:2HWL|rcsb pdb:2OYH|rcsb pdb:2OYI|rcsb pdb:2VDO|rcsb pdb:2VDP|rcsb pdb:2VDQ|rcsb pdb:2VDR|rcsb pdb:2VR3|rcsb pdb:2XNX|rcsb pdb:2XNY|rcsb pdb:2Y7L|rcsb pdb:2Z4E|rcsb pdb:3BVH|rcsb pdb:3E1I|rcsb pdb:2Q9I|rcsb pdb:3FIB|rcsb pdb:3GHG|rcsb pdb:3H32|rcsb pdb:3HUS|rcsb pdb:4B60|reactome:R-HSA-114608|reactome:R-HSA-1236974|reactome:R-HSA-140875|reactome:R-HSA-166058|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5674135|reactome:R-HSA-5686938|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8957275|reactome:R-HSA-9649948|reactome:R-HSA-9656223|dip:DIP-29644N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8HzwuoBdBWw+LZKg6WpYxMKnfYE9606 rogid:QKWesyU4/fduceFtu5zq31oGhYI9606 rigid:Djjt3Q24jgkzG4WOluz5tu4rtRs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92667 uniprotkb:P11940 intact:EBI-2119593|uniprotkb:Q13320|uniprotkb:Q9BW14|uniprotkb:A8K8Q1|uniprotkb:D3DTZ0|ensembl:ENSP00000337736|ensembl:ENSP00000443139|ensembl:ENSP00000459895|ensembl:ENSP00000459968|ensembl:ENSP00000478212 intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004 psi-mi:akap1_human(display_long)|uniprotkb:AKAP1(gene name)|psi-mi:AKAP1(display_short)|uniprotkb:AKAP149(gene name synonym)|uniprotkb:PRKA1(gene name synonym)|uniprotkb:Protein kinase A-anchoring protein 1(gene name synonym)|uniprotkb:A-kinase anchor protein 149 kDa(gene name synonym)|uniprotkb:Dual specificity A-kinase-anchoring protein 1(gene name synonym)|uniprotkb:Spermatid A-kinase anchor protein 84(gene name synonym) psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25475929|imex:IM-26985-225 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880678.1|refseq:XP_016880679.1|refseq:XP_016880680.1|refseq:NP_001229831.1|refseq:NP_001229832.1|refseq:NP_003479.1|refseq:XP_005257764.1|refseq:XP_005257766.1|ensembl:ENSG00000121057(gene)|ensembl:ENST00000337714(transcript)|ensembl:ENST00000539273(transcript)|ensembl:ENST00000571629(transcript)|ensembl:ENST00000572557(transcript)|ensembl:ENST00000621116(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR002999(Tudor)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR035437|interpro:IPR036612|mint:Q92667|reactome:R-HSA-8949215|reactome:R-HSA-983231 interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8HzwuoBdBWw+LZKg6WpYxMKnfYE9606 rogid:XudTSPq2h9ckKAc48X88RVafPRU9606 rigid:Djjt3Q24jgkzG4WOluz5tu4rtRs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92667 uniprotkb:Q9UJ04 intact:EBI-2119593|uniprotkb:Q13320|uniprotkb:Q9BW14|uniprotkb:A8K8Q1|uniprotkb:D3DTZ0|ensembl:ENSP00000337736|ensembl:ENSP00000443139|ensembl:ENSP00000459895|ensembl:ENSP00000459968|ensembl:ENSP00000478212 intact:EBI-308511|ensembl:ENSP00000410943|uniprotkb:O94828|uniprotkb:Q96GW8|uniprotkb:B4DYQ2 psi-mi:akap1_human(display_long)|uniprotkb:AKAP1(gene name)|psi-mi:AKAP1(display_short)|uniprotkb:AKAP149(gene name synonym)|uniprotkb:PRKA1(gene name synonym)|uniprotkb:Protein kinase A-anchoring protein 1(gene name synonym)|uniprotkb:A-kinase anchor protein 149 kDa(gene name synonym)|uniprotkb:Dual specificity A-kinase-anchoring protein 1(gene name synonym)|uniprotkb:Spermatid A-kinase anchor protein 84(gene name synonym) psi-mi:tsyl4_human(display_long)|uniprotkb:TSPYL4(gene name)|psi-mi:TSPYL4(display_short)|uniprotkb:KIAA0721(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25475929|imex:IM-26985-225 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880678.1|refseq:XP_016880679.1|refseq:XP_016880680.1|refseq:NP_001229831.1|refseq:NP_001229832.1|refseq:NP_003479.1|refseq:XP_005257764.1|refseq:XP_005257766.1|ensembl:ENSG00000121057(gene)|ensembl:ENST00000337714(transcript)|ensembl:ENST00000539273(transcript)|ensembl:ENST00000571629(transcript)|ensembl:ENST00000572557(transcript)|ensembl:ENST00000621116(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR002999(Tudor)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR035437|interpro:IPR036612|mint:Q92667|reactome:R-HSA-8949215|reactome:R-HSA-983231 ensembl:ENSG00000187189(gene)|ensembl:ENST00000420283(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0042393"(histone binding)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q9UJ04|refseq:NP_067680.3 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8HzwuoBdBWw+LZKg6WpYxMKnfYE9606 rogid:xcAq3OJVo+H+zV8Tq/wwdwthb3M9606 rigid:Djjt3Q24jgkzG4WOluz5tu4rtRs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92667 uniprotkb:P02787 intact:EBI-2119593|uniprotkb:Q13320|uniprotkb:Q9BW14|uniprotkb:A8K8Q1|uniprotkb:D3DTZ0|ensembl:ENSP00000337736|ensembl:ENSP00000443139|ensembl:ENSP00000459895|ensembl:ENSP00000459968|ensembl:ENSP00000478212 intact:EBI-714319|uniprotkb:O43890|uniprotkb:Q9NQB8|uniprotkb:Q9UHV0|uniprotkb:Q1HBA5|ensembl:ENSP00000385834 psi-mi:akap1_human(display_long)|uniprotkb:AKAP1(gene name)|psi-mi:AKAP1(display_short)|uniprotkb:AKAP149(gene name synonym)|uniprotkb:PRKA1(gene name synonym)|uniprotkb:Protein kinase A-anchoring protein 1(gene name synonym)|uniprotkb:A-kinase anchor protein 149 kDa(gene name synonym)|uniprotkb:Dual specificity A-kinase-anchoring protein 1(gene name synonym)|uniprotkb:Spermatid A-kinase anchor protein 84(gene name synonym) psi-mi:trfe_human(display_long)|uniprotkb:Siderophilin(gene name synonym)|uniprotkb:Beta-1 metal-binding globulin(gene name synonym)|uniprotkb:TF(gene name)|psi-mi:TF(display_short)|uniprotkb:PRO1400(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25475929|imex:IM-26985-225 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880678.1|refseq:XP_016880679.1|refseq:XP_016880680.1|refseq:NP_001229831.1|refseq:NP_001229832.1|refseq:NP_003479.1|refseq:XP_005257764.1|refseq:XP_005257766.1|ensembl:ENSG00000121057(gene)|ensembl:ENST00000337714(transcript)|ensembl:ENST00000539273(transcript)|ensembl:ENST00000571629(transcript)|ensembl:ENST00000572557(transcript)|ensembl:ENST00000621116(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR002999(Tudor)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR035437|interpro:IPR036612|mint:Q92667|reactome:R-HSA-8949215|reactome:R-HSA-983231 refseq:NP_001054.1|rcsb pdb:1JQF|rcsb pdb:1N7W|rcsb pdb:1N7X|rcsb pdb:1N84|rcsb pdb:1OQG|rcsb pdb:1OQH|rcsb pdb:1RYO|rcsb pdb:1SUV|rcsb pdb:2HAU|rcsb pdb:2HAV|rcsb pdb:2O7U|rcsb pdb:2O84|rcsb pdb:3FGS|rcsb pdb:3QYT|rcsb pdb:3S9L|rcsb pdb:3S9M|rcsb pdb:1FQF|rcsb pdb:3S9N|rcsb pdb:3SKP|rcsb pdb:3V83|rcsb pdb:3V89|rcsb pdb:3V8X|rcsb pdb:4H0W|rcsb pdb:4X1B|rcsb pdb:4X1D|rcsb pdb:5DYH|rcsb pdb:5H52|rcsb pdb:5WTD|rcsb pdb:5X5P|rcsb pdb:5Y6K|rcsb pdb:6CTC|rcsb pdb:6D03|rcsb pdb:6D04|rcsb pdb:6D05|rcsb pdb:3VE1|rcsb pdb:6JAS|rcsb pdb:6SOY|rcsb pdb:6SOZ|rcsb pdb:6UJ6|reactome:R-HSA-114608|reactome:R-HSA-381426|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8957275|reactome:R-HSA-917937|reactome:R-HSA-917977|go:"GO:0034986"(iron chaperone activity)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0045178"(basal part of cell)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:0072562"(blood microparticle)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:2000147"(positive regulation of cell motility)|interpro:IPR001156(Peptidase S60, transferrin lactoferrin)|interpro:IPR016357(Transferrin)|interpro:IPR018195|interpro:IPR030685|mint:P02787|rcsb pdb:1A8E|go:"GO:0034774"(secretory granule lumen)|rcsb pdb:1A8F|rcsb pdb:1B3E|rcsb pdb:1BP5|rcsb pdb:1BTJ|rcsb pdb:1D3K|rcsb pdb:1D4N|rcsb pdb:1DTG|rcsb pdb:1FQE|ensembl:ENSG00000091513(gene)|ensembl:ENST00000402696(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007015"(actin filament organization)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008199"(ferric iron binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031982"(vesicle)|go:"GO:0034756"(regulation of iron ion transport)|refseq:XP_016862578.1|refseq:XP_016862579.1|dip:DIP-2738N - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8HzwuoBdBWw+LZKg6WpYxMKnfYE9606 rogid:CN9nME9TVV6/FGrhH6XHtJF9/HI9606 rigid:Djjt3Q24jgkzG4WOluz5tu4rtRs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92667 uniprotkb:P00738 intact:EBI-2119593|uniprotkb:Q13320|uniprotkb:Q9BW14|uniprotkb:A8K8Q1|uniprotkb:D3DTZ0|ensembl:ENSP00000337736|ensembl:ENSP00000443139|ensembl:ENSP00000459895|ensembl:ENSP00000459968|ensembl:ENSP00000478212 intact:EBI-1220767|uniprotkb:P00737|uniprotkb:Q0VAC4|uniprotkb:Q2PP15|uniprotkb:Q3B7J0|uniprotkb:Q6LBY9|uniprotkb:B0AZL5|uniprotkb:Q9UC67|uniprotkb:Q0VAC5|ensembl:ENSP00000348170 psi-mi:akap1_human(display_long)|uniprotkb:AKAP1(gene name)|psi-mi:AKAP1(display_short)|uniprotkb:AKAP149(gene name synonym)|uniprotkb:PRKA1(gene name synonym)|uniprotkb:Protein kinase A-anchoring protein 1(gene name synonym)|uniprotkb:A-kinase anchor protein 149 kDa(gene name synonym)|uniprotkb:Dual specificity A-kinase-anchoring protein 1(gene name synonym)|uniprotkb:Spermatid A-kinase anchor protein 84(gene name synonym) psi-mi:hpt_human(display_long)|uniprotkb:HP(gene name)|psi-mi:HP(display_short)|uniprotkb:Zonulin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25475929|imex:IM-26985-225 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880678.1|refseq:XP_016880679.1|refseq:XP_016880680.1|refseq:NP_001229831.1|refseq:NP_001229832.1|refseq:NP_003479.1|refseq:XP_005257764.1|refseq:XP_005257766.1|ensembl:ENSG00000121057(gene)|ensembl:ENST00000337714(transcript)|ensembl:ENST00000539273(transcript)|ensembl:ENST00000571629(transcript)|ensembl:ENST00000572557(transcript)|ensembl:ENST00000621116(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR002999(Tudor)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR035437|interpro:IPR036612|mint:Q92667|reactome:R-HSA-8949215|reactome:R-HSA-983231 refseq:NP_001119574.1|refseq:NP_005134.1|refseq:NP_001305067.1|ensembl:ENSG00000257017(gene)|ensembl:ENST00000355906(transcript)|go:"GO:0002526"(acute inflammatory response)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006952"(defense response)|go:"GO:0006953"(acute-phase response)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016209"(antioxidant activity)|go:"GO:0030492"(hemoglobin binding)|go:"GO:0031638"(zymogen activation)|go:"GO:0031838"(haptoglobin-hemoglobin complex)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0051354"(negative regulation of oxidoreductase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071682"(endocytic vesicle lumen)|interpro:IPR008292(Haptoglobin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR035976|interpro:IPR043504|mint:P00738|rcsb pdb:4WJG|rcsb pdb:4X0L|rcsb pdb:5HU6|rcsb pdb:6TB2|reactome:R-HSA-2168880|go:"GO:0072562"(blood microparticle)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:2000296"(negative regulation of hydrogen peroxide catabolic process)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|reactome:R-HSA-6798695 - - comment:"author score: 33" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8HzwuoBdBWw+LZKg6WpYxMKnfYE9606 rogid:IsI1hIXfhsW0goXPHsoADxl7V5g9606 rigid:Djjt3Q24jgkzG4WOluz5tu4rtRs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92667 uniprotkb:P16403 intact:EBI-2119593|uniprotkb:Q13320|uniprotkb:Q9BW14|uniprotkb:A8K8Q1|uniprotkb:D3DTZ0|ensembl:ENSP00000337736|ensembl:ENSP00000443139|ensembl:ENSP00000459895|ensembl:ENSP00000459968|ensembl:ENSP00000478212 intact:EBI-358372|ensembl:ENSP00000339566|uniprotkb:A8K4I2 psi-mi:akap1_human(display_long)|uniprotkb:AKAP1(gene name)|psi-mi:AKAP1(display_short)|uniprotkb:AKAP149(gene name synonym)|uniprotkb:PRKA1(gene name synonym)|uniprotkb:Protein kinase A-anchoring protein 1(gene name synonym)|uniprotkb:A-kinase anchor protein 149 kDa(gene name synonym)|uniprotkb:Dual specificity A-kinase-anchoring protein 1(gene name synonym)|uniprotkb:Spermatid A-kinase anchor protein 84(gene name synonym) psi-mi:h12_human(display_long)|uniprotkb:H1-2(gene name)|psi-mi:H1-2(display_short)|uniprotkb:H1F2(gene name synonym)|uniprotkb:HIST1H1C(gene name synonym)|uniprotkb:Histone H1c(gene name synonym)|uniprotkb:Histone H1d(gene name synonym)|uniprotkb:Histone H1s-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25475929|imex:IM-26985-225 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880678.1|refseq:XP_016880679.1|refseq:XP_016880680.1|refseq:NP_001229831.1|refseq:NP_001229832.1|refseq:NP_003479.1|refseq:XP_005257764.1|refseq:XP_005257766.1|ensembl:ENSG00000121057(gene)|ensembl:ENST00000337714(transcript)|ensembl:ENST00000539273(transcript)|ensembl:ENST00000571629(transcript)|ensembl:ENST00000572557(transcript)|ensembl:ENST00000621116(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR002999(Tudor)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR035437|interpro:IPR036612|mint:Q92667|reactome:R-HSA-8949215|reactome:R-HSA-983231 refseq:NP_005310.1|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P16403|reactome:R-HSA-140342|reactome:R-HSA-2559584|ensembl:ENSG00000187837(gene)|ensembl:ENST00000343677(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|dip:DIP-36359N - - comment:"author score: 35" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8HzwuoBdBWw+LZKg6WpYxMKnfYE9606 rogid:eRT5bTyBJUg6nRANMRYZekT4N+g9606 rigid:Djjt3Q24jgkzG4WOluz5tu4rtRs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92667 uniprotkb:P22694 intact:EBI-2119593|uniprotkb:Q13320|uniprotkb:Q9BW14|uniprotkb:A8K8Q1|uniprotkb:D3DTZ0|ensembl:ENSP00000337736|ensembl:ENSP00000443139|ensembl:ENSP00000459895|ensembl:ENSP00000459968|ensembl:ENSP00000478212 intact:EBI-2679622|uniprotkb:Q14VH1|uniprotkb:Q5BNF3|uniprotkb:Q96B09|uniprotkb:Q59GC0|uniprotkb:Q5BNF2|uniprotkb:Q8IYR5|uniprotkb:Q8IZQ0|uniprotkb:Q5BNE9|uniprotkb:B4E2Q1|uniprotkb:Q7Z3M1|uniprotkb:Q5BNF1|uniprotkb:Q5CZ92|uniprotkb:Q5T1K3|uniprotkb:Q5BNF0|uniprotkb:B4DKB0|uniprotkb:B1APG4|ensembl:ENSP00000359723 psi-mi:akap1_human(display_long)|uniprotkb:AKAP1(gene name)|psi-mi:AKAP1(display_short)|uniprotkb:AKAP149(gene name synonym)|uniprotkb:PRKA1(gene name synonym)|uniprotkb:Protein kinase A-anchoring protein 1(gene name synonym)|uniprotkb:A-kinase anchor protein 149 kDa(gene name synonym)|uniprotkb:Dual specificity A-kinase-anchoring protein 1(gene name synonym)|uniprotkb:Spermatid A-kinase anchor protein 84(gene name synonym) psi-mi:kapcb_human(display_long)|uniprotkb:PRKACB(gene name)|psi-mi:PRKACB(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25475929|imex:IM-26985-225 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880678.1|refseq:XP_016880679.1|refseq:XP_016880680.1|refseq:NP_001229831.1|refseq:NP_001229832.1|refseq:NP_003479.1|refseq:XP_005257764.1|refseq:XP_005257766.1|ensembl:ENSG00000121057(gene)|ensembl:ENST00000337714(transcript)|ensembl:ENST00000539273(transcript)|ensembl:ENST00000571629(transcript)|ensembl:ENST00000572557(transcript)|ensembl:ENST00000621116(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR002999(Tudor)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR035437|interpro:IPR036612|mint:Q92667|reactome:R-HSA-8949215|reactome:R-HSA-983231 refseq:NP_001229786.1|refseq:NP_001229787.1|refseq:NP_001229788.1|refseq:NP_001229789.1|refseq:NP_001229790.1|refseq:NP_001229791.1|refseq:NP_002722.1|refseq:NP_891993.1|refseq:NP_997461.1|refseq:XP_005271076.1|refseq:XP_006710821.1|refseq:NP_001287844.1|refseq:NP_001287845.1|refseq:NP_001287846.1|ensembl:ENSG00000142875(gene)|ensembl:ENST00000370689(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0003091"(renal water homeostasis)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051447"(negative regulation of meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070613"(regulation of protein processing)|go:"GO:0097338"(response to clozapine)|go:"GO:0097546"(ciliary base)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901621"(negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P22694|interpro:IPR044109|reactome:R-HSA-111931|reactome:R-HSA-163358|reactome:R-HSA-163560|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-381676|reactome:R-HSA-392517|reactome:R-HSA-422356|reactome:R-HSA-432040|reactome:R-HSA-4420097|reactome:R-HSA-442720|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5610787|reactome:R-HSA-5621575|reactome:R-HSA-5687128|reactome:R-HSA-8853659|reactome:R-HSA-8963896|reactome:R-HSA-9010642|reactome:R-HSA-9634600|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231 - - comment:"author score: 67" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8HzwuoBdBWw+LZKg6WpYxMKnfYE9606 rogid:FEzsjRJZlkFu5+KK4abzu7oAY9E9606 rigid:Djjt3Q24jgkzG4WOluz5tu4rtRs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92667 uniprotkb:P31323 intact:EBI-2119593|uniprotkb:Q13320|uniprotkb:Q9BW14|uniprotkb:A8K8Q1|uniprotkb:D3DTZ0|ensembl:ENSP00000337736|ensembl:ENSP00000443139|ensembl:ENSP00000459895|ensembl:ENSP00000459968|ensembl:ENSP00000478212 intact:EBI-2930670|ensembl:ENSP00000265717|ensembl:ENSP00000491687|uniprotkb:A4D0R9 psi-mi:akap1_human(display_long)|uniprotkb:AKAP1(gene name)|psi-mi:AKAP1(display_short)|uniprotkb:AKAP149(gene name synonym)|uniprotkb:PRKA1(gene name synonym)|uniprotkb:Protein kinase A-anchoring protein 1(gene name synonym)|uniprotkb:A-kinase anchor protein 149 kDa(gene name synonym)|uniprotkb:Dual specificity A-kinase-anchoring protein 1(gene name synonym)|uniprotkb:Spermatid A-kinase anchor protein 84(gene name synonym) psi-mi:kap3_human(display_long)|uniprotkb:PRKAR2B(gene name)|psi-mi:PRKAR2B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25475929|imex:IM-26985-225 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880678.1|refseq:XP_016880679.1|refseq:XP_016880680.1|refseq:NP_001229831.1|refseq:NP_001229832.1|refseq:NP_003479.1|refseq:XP_005257764.1|refseq:XP_005257766.1|ensembl:ENSG00000121057(gene)|ensembl:ENST00000337714(transcript)|ensembl:ENST00000539273(transcript)|ensembl:ENST00000571629(transcript)|ensembl:ENST00000572557(transcript)|ensembl:ENST00000621116(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR002999(Tudor)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR035437|interpro:IPR036612|mint:Q92667|reactome:R-HSA-8949215|reactome:R-HSA-983231 ensembl:ENSG00000005249(gene)|ensembl:ENSG00000284096(gene)|ensembl:ENST00000265717(transcript)|ensembl:ENST00000639737(transcript)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0007612"(learning)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097332"(response to antipsychotic drug)|go:"GO:0097338"(response to clozapine)|go:"GO:0097546"(ciliary base)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|mint:P31323|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-5620912|reactome:R-HSA-8854518|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|refseq:NP_002727.2|dip:DIP-554N - - comment:"author score: 84" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8HzwuoBdBWw+LZKg6WpYxMKnfYE9606 rogid:P643dCCYtpt/EkR7tmZrbo97FLE9606 rigid:Djjt3Q24jgkzG4WOluz5tu4rtRs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92667 uniprotkb:P13861 intact:EBI-2119593|uniprotkb:Q13320|uniprotkb:Q9BW14|uniprotkb:A8K8Q1|uniprotkb:D3DTZ0|ensembl:ENSP00000337736|ensembl:ENSP00000443139|ensembl:ENSP00000459895|ensembl:ENSP00000459968|ensembl:ENSP00000478212 intact:EBI-2556122|intact:EBI-6116682|uniprotkb:Q9BUB1|uniprotkb:Q16823|ensembl:ENSP00000265563|ensembl:ENSP00000394041|intact:EBI-10961724 psi-mi:akap1_human(display_long)|uniprotkb:AKAP1(gene name)|psi-mi:AKAP1(display_short)|uniprotkb:AKAP149(gene name synonym)|uniprotkb:PRKA1(gene name synonym)|uniprotkb:Protein kinase A-anchoring protein 1(gene name synonym)|uniprotkb:A-kinase anchor protein 149 kDa(gene name synonym)|uniprotkb:Dual specificity A-kinase-anchoring protein 1(gene name synonym)|uniprotkb:Spermatid A-kinase anchor protein 84(gene name synonym) psi-mi:kap2_human(display_long)|uniprotkb:PKR2(gene name synonym)|uniprotkb:PRKAR2(gene name synonym)|uniprotkb:PRKAR2A(gene name)|psi-mi:PRKAR2A(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25475929|imex:IM-26985-225 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_016880678.1|refseq:XP_016880679.1|refseq:XP_016880680.1|refseq:NP_001229831.1|refseq:NP_001229832.1|refseq:NP_003479.1|refseq:XP_005257764.1|refseq:XP_005257766.1|ensembl:ENSG00000121057(gene)|ensembl:ENST00000337714(transcript)|ensembl:ENST00000539273(transcript)|ensembl:ENST00000571629(transcript)|ensembl:ENST00000572557(transcript)|ensembl:ENST00000621116(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0140374"(antiviral innate immune response)|interpro:IPR002999(Tudor)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR035437|interpro:IPR036612|mint:Q92667|reactome:R-HSA-8949215|reactome:R-HSA-983231 dip:DIP-552N|refseq:XP_011532244.1|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|mint:P13861|rcsb pdb:2IZX|rcsb pdb:2KYG|rcsb pdb:4ZP3|rcsb pdb:5H78|rcsb pdb:5XBY|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-9010642|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|ensembl:ENSG00000114302(gene)|ensembl:ENST00000265563(transcript)|ensembl:ENST00000454963(transcript)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097546"(ciliary base)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|refseq:NP_001308911.1|refseq:NP_001308912.1|refseq:NP_004148.1|refseq:XP_016862304.1 - - comment:"author score: 205" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8HzwuoBdBWw+LZKg6WpYxMKnfYE9606 rogid:9Jf7EDZ9CZjeRERWwLAR0NyqFGQ9606 rigid:Djjt3Q24jgkzG4WOluz5tu4rtRs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q4VCS5 uniprotkb:Q92665 intact:EBI-2511319|ensembl:ENSP00000361027|uniprotkb:Q504X5|uniprotkb:Q9UPT1|uniprotkb:Q9HD27 intact:EBI-720602|uniprotkb:Q8WTV8|uniprotkb:Q5VYC8|uniprotkb:B2RCS3|ensembl:ENSP00000315397 psi-mi:amot_human(display_long)|uniprotkb:AMOT(gene name)|psi-mi:AMOT(display_short)|uniprotkb:KIAA1071(gene name synonym) psi-mi:rt31_human(display_long)|uniprotkb:Imogen 38(gene name synonym)|uniprotkb:MRPS31(gene name)|psi-mi:MRPS31(display_short)|uniprotkb:IMOGN38(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS31(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25475965|imex:IM-26985-381 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000126016(gene)|ensembl:ENST00000371959(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006935"(chemotaxis)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035329"(hippo signaling)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q4VCS5|rcsb pdb:6JJX|reactome:R-HSA-2028269|refseq:XP_011529177.1|refseq:NP_001106962.1|refseq:NP_573572.1|refseq:XP_005262144.1|refseq:XP_005262147.1|refseq:XP_016884778.1|dip:DIP-53711N refseq:NP_005821.2|ensembl:ENSG00000102738(gene)|ensembl:ENST00000323563(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0019904"(protein domain specific binding)|interpro:IPR026299|mint:Q92665|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5O9K+GgX1s0Hn5optTeKPOs+X1s9606 rogid:Le0Lq+WW56dP5NLuMB2eKFeg6b09606 rigid:OgxuVh1oQ6vzhM6VpmZl4z5gOFk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q4VCS5 uniprotkb:P82664 intact:EBI-2511319|ensembl:ENSP00000361027|uniprotkb:Q504X5|uniprotkb:Q9UPT1|uniprotkb:Q9HD27 intact:EBI-1048271|uniprotkb:Q9H3E5|uniprotkb:Q9NVR3|uniprotkb:B2RE89|ensembl:ENSP00000053468 psi-mi:amot_human(display_long)|uniprotkb:AMOT(gene name)|psi-mi:AMOT(display_short)|uniprotkb:KIAA1071(gene name synonym) psi-mi:rt10_human(display_long)|uniprotkb:MRPS10(gene name)|psi-mi:MRPS10(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein uS10m(gene name synonym)|uniprotkb:MSTP040(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25475965|imex:IM-26985-381 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000126016(gene)|ensembl:ENST00000371959(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006935"(chemotaxis)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035329"(hippo signaling)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q4VCS5|rcsb pdb:6JJX|reactome:R-HSA-2028269|refseq:XP_011529177.1|refseq:NP_001106962.1|refseq:NP_573572.1|refseq:XP_005262144.1|refseq:XP_005262147.1|refseq:XP_016884778.1|dip:DIP-53711N refseq:NP_060611.2|ensembl:ENSG00000048544(gene)|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|ensembl:ENST00000053468(transcript)|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|interpro:IPR027486|interpro:IPR036838|interpro:IPR040055|mint:P82664|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|dip:DIP-50902N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5O9K+GgX1s0Hn5optTeKPOs+X1s9606 rogid:D6kypsC/rbFvPq5Y1YX9/DXtwtk9606 rigid:OgxuVh1oQ6vzhM6VpmZl4z5gOFk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q4VCS5 uniprotkb:P82933 intact:EBI-2511319|ensembl:ENSP00000361027|uniprotkb:Q504X5|uniprotkb:Q9UPT1|uniprotkb:Q9HD27 intact:EBI-721385|intact:EBI-1049991|uniprotkb:Q6PG40|ensembl:ENSP00000258455 psi-mi:amot_human(display_long)|uniprotkb:AMOT(gene name)|psi-mi:AMOT(display_short)|uniprotkb:KIAA1071(gene name synonym) psi-mi:rt09_human(display_long)|uniprotkb:MRPS9(gene name)|psi-mi:MRPS9(display_short)|uniprotkb:RPMS9(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS9m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25475965|imex:IM-26985-381 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000126016(gene)|ensembl:ENST00000371959(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006935"(chemotaxis)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035329"(hippo signaling)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q4VCS5|rcsb pdb:6JJX|reactome:R-HSA-2028269|refseq:XP_011529177.1|refseq:NP_001106962.1|refseq:NP_573572.1|refseq:XP_005262144.1|refseq:XP_005262147.1|refseq:XP_016884778.1|dip:DIP-53711N refseq:NP_872578.1|ensembl:ENSG00000135972(gene)|ensembl:ENST00000258455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|interpro:IPR000754(Ribosomal protein S9)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR020574|mint:P82933|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:6ZSE - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5O9K+GgX1s0Hn5optTeKPOs+X1s9606 rogid:XNB4GL84eYgYFEB3WxOtoD3Ub989606 rigid:OgxuVh1oQ6vzhM6VpmZl4z5gOFk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q4VCS5 uniprotkb:P51398 intact:EBI-2511319|ensembl:ENSP00000361027|uniprotkb:Q504X5|uniprotkb:Q9UPT1|uniprotkb:Q9HD27 intact:EBI-355912|uniprotkb:Q13044|uniprotkb:Q96Q20|uniprotkb:Q68CT7|uniprotkb:B4DP59|uniprotkb:E7EM60|uniprotkb:B4DY62|ensembl:ENSP00000341692|ensembl:ENSP00000357320 psi-mi:amot_human(display_long)|uniprotkb:AMOT(gene name)|psi-mi:AMOT(display_short)|uniprotkb:KIAA1071(gene name synonym) psi-mi:rt29_human(display_long)|uniprotkb:DAP3(gene name)|psi-mi:DAP3(display_short)|uniprotkb:MRPS29(gene name synonym)|uniprotkb:Death-associated protein 3(gene name synonym)|uniprotkb:Ionizing radiation resistance conferring protein(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS29(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25475965|imex:IM-26985-381 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000126016(gene)|ensembl:ENST00000371959(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006935"(chemotaxis)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035329"(hippo signaling)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q4VCS5|rcsb pdb:6JJX|reactome:R-HSA-2028269|refseq:XP_011529177.1|refseq:NP_001106962.1|refseq:NP_573572.1|refseq:XP_005262144.1|refseq:XP_005262147.1|refseq:XP_016884778.1|dip:DIP-53711N refseq:NP_001186778.1|refseq:NP_004623.1|refseq:NP_387506.1|refseq:NP_001186779.1|refseq:NP_001186780.1|refseq:XP_005245537.1|refseq:XP_005245538.1|ensembl:ENSG00000132676(gene)|ensembl:ENST00000343043(transcript)|ensembl:ENST00000368336(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0097190"(apoptotic signaling pathway)|interpro:IPR008092(Death associated protein 3)|interpro:IPR019368|interpro:IPR027417|mint:P51398|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:XP_016857780.1|refseq:XP_016857781.1|refseq:XP_016857782.1 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5O9K+GgX1s0Hn5optTeKPOs+X1s9606 rogid:xSIyqKH4F49Iu+AVuVThJWsi9EA9606 rigid:OgxuVh1oQ6vzhM6VpmZl4z5gOFk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q4VCS5 uniprotkb:Q9Y3D9 intact:EBI-2511319|ensembl:ENSP00000361027|uniprotkb:Q504X5|uniprotkb:Q9UPT1|uniprotkb:Q9HD27 intact:EBI-1054270|uniprotkb:Q96Q24|uniprotkb:Q9BWH8|uniprotkb:Q9P053|uniprotkb:B2R6V3|ensembl:ENSP00000320184 psi-mi:amot_human(display_long)|uniprotkb:AMOT(gene name)|psi-mi:AMOT(display_short)|uniprotkb:KIAA1071(gene name synonym) psi-mi:rt23_human(display_long)|uniprotkb:MRPS23(gene name)|psi-mi:MRPS23(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein mS23(gene name synonym)|uniprotkb:CGI-138(orf name)|uniprotkb:HSPC329(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25475965|imex:IM-26985-381 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000126016(gene)|ensembl:ENST00000371959(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006935"(chemotaxis)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035329"(hippo signaling)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q4VCS5|rcsb pdb:6JJX|reactome:R-HSA-2028269|refseq:XP_011529177.1|refseq:NP_001106962.1|refseq:NP_573572.1|refseq:XP_005262144.1|refseq:XP_005262147.1|refseq:XP_016884778.1|dip:DIP-53711N refseq:NP_057154.2|ensembl:ENSG00000181610(gene)|ensembl:ENST00000313608(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0031965"(nuclear membrane)|interpro:IPR019520|interpro:IPR023611|mint:Q9Y3D9|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5O9K+GgX1s0Hn5optTeKPOs+X1s9606 rogid:6Iyu6KkT1Y0+n0LKWy5Gf0DkhHw9606 rigid:OgxuVh1oQ6vzhM6VpmZl4z5gOFk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q4VCS5 uniprotkb:Q96EL2 intact:EBI-2511319|ensembl:ENSP00000361027|uniprotkb:Q504X5|uniprotkb:Q9UPT1|uniprotkb:Q9HD27 intact:EBI-1055789|uniprotkb:P82668|uniprotkb:Q96Q23|uniprotkb:Q9P047|uniprotkb:A4D1U9|ensembl:ENSP00000318158 psi-mi:amot_human(display_long)|uniprotkb:AMOT(gene name)|psi-mi:AMOT(display_short)|uniprotkb:KIAA1071(gene name synonym) psi-mi:rt24_human(display_long)|uniprotkb:bMRP-47(gene name synonym)|uniprotkb:MRPS24(gene name)|psi-mi:MRPS24(display_short)|uniprotkb:HSPC335(orf name)|uniprotkb:Mitochondrial small ribosomal subunit protein uS3m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25475965|imex:IM-26985-381 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000126016(gene)|ensembl:ENST00000371959(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006935"(chemotaxis)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035329"(hippo signaling)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q4VCS5|rcsb pdb:6JJX|reactome:R-HSA-2028269|refseq:XP_011529177.1|refseq:NP_001106962.1|refseq:NP_573572.1|refseq:XP_005262144.1|refseq:XP_005262147.1|refseq:XP_016884778.1|dip:DIP-53711N refseq:NP_114403.1|ensembl:ENSG00000062582(gene)|ensembl:ENST00000317534(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR026146|mint:Q96EL2|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - comment:"author score: 35" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5O9K+GgX1s0Hn5optTeKPOs+X1s9606 rogid:OEtFmhoLM1Sw9YVrL88HZQ5Ju0g9606 rigid:OgxuVh1oQ6vzhM6VpmZl4z5gOFk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q4VCS5 uniprotkb:Q9Y399 intact:EBI-2511319|ensembl:ENSP00000361027|uniprotkb:Q504X5|uniprotkb:Q9UPT1|uniprotkb:Q9HD27 intact:EBI-2880048|intact:EBI-28977422|ensembl:ENSP00000241600|ensembl:ENSP00000360850|uniprotkb:Q5T899|uniprotkb:Q9BSQ4 psi-mi:amot_human(display_long)|uniprotkb:AMOT(gene name)|psi-mi:AMOT(display_short)|uniprotkb:KIAA1071(gene name synonym) psi-mi:rt02_human(display_long)|uniprotkb:MRPS2(gene name)|psi-mi:MRPS2(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein uS2m(gene name synonym)|uniprotkb:CGI-91(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25475965|imex:IM-26985-381 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000126016(gene)|ensembl:ENST00000371959(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006935"(chemotaxis)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035329"(hippo signaling)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q4VCS5|rcsb pdb:6JJX|reactome:R-HSA-2028269|refseq:XP_011529177.1|refseq:NP_001106962.1|refseq:NP_573572.1|refseq:XP_005262144.1|refseq:XP_005262147.1|refseq:XP_016884778.1|dip:DIP-53711N rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:6RW5|ensembl:ENST00000241600(transcript)|ensembl:ENST00000371785(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0061668"(mitochondrial ribosome assembly)|ensembl:ENSG00000122140(gene)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005706(Ribosomal protein S2, bacterial-type)|interpro:IPR018130|interpro:IPR023591|mint:Q9Y399|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|ensembl:ENSP00000241600|ensembl:ENSP00000360850|refseq:NP_057118.1 - - comment:"author score: 44" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5O9K+GgX1s0Hn5optTeKPOs+X1s9606 rogid:tlWj8Un0CmbnBQtZMYlJpvIpc/09606 rigid:OgxuVh1oQ6vzhM6VpmZl4z5gOFk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q4VCS5 uniprotkb:Q9Y2Q9 intact:EBI-2511319|ensembl:ENSP00000361027|uniprotkb:Q504X5|uniprotkb:Q9UPT1|uniprotkb:Q9HD27 intact:EBI-5325249|ensembl:ENSP00000276585|uniprotkb:B2RDZ7|uniprotkb:Q96Q21 psi-mi:amot_human(display_long)|uniprotkb:AMOT(gene name)|psi-mi:AMOT(display_short)|uniprotkb:KIAA1071(gene name synonym) psi-mi:rt28_human(display_long)|uniprotkb:Mitochondrial small ribosomal subunit protein bS1m(gene name synonym)|uniprotkb:HSPC007(orf name)|uniprotkb:MRPS28(gene name)|psi-mi:MRPS28(display_short)|uniprotkb:MRPS35(gene name synonym)|uniprotkb:28S ribosomal protein S35, mitochondrial(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25475965|imex:IM-26985-381 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000126016(gene)|ensembl:ENST00000371959(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006935"(chemotaxis)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035329"(hippo signaling)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q4VCS5|rcsb pdb:6JJX|reactome:R-HSA-2028269|refseq:XP_011529177.1|refseq:NP_001106962.1|refseq:NP_573572.1|refseq:XP_005262144.1|refseq:XP_005262147.1|refseq:XP_016884778.1|dip:DIP-53711N ensembl:ENST00000276585(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR019375|mint:Q9Y2Q9|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|ensembl:ENSG00000147586(gene)|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:NP_054737.1 - - comment:"author score: 48" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5O9K+GgX1s0Hn5optTeKPOs+X1s9606 rogid:E78l52n5CxYuz9U1JoMSG5jJjMA9606 rigid:OgxuVh1oQ6vzhM6VpmZl4z5gOFk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q4VCS5 uniprotkb:Q8IY63 intact:EBI-2511319|ensembl:ENSP00000361027|uniprotkb:Q504X5|uniprotkb:Q9UPT1|uniprotkb:Q9HD27 intact:EBI-1057112|uniprotkb:Q63HK7|uniprotkb:Q8NDN0|uniprotkb:Q8WXD1|uniprotkb:Q96CM5|intact:EBI-2514012|uniprotkb:Q8TEN8|intact:EBI-28986258|ensembl:ENSP00000387739 psi-mi:amot_human(display_long)|uniprotkb:AMOT(gene name)|psi-mi:AMOT(display_short)|uniprotkb:KIAA1071(gene name synonym) psi-mi:amol1_human(display_long)|uniprotkb:AMOTL1(gene name)|psi-mi:AMOTL1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25475965|imex:IM-26985-381 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000126016(gene)|ensembl:ENST00000371959(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006935"(chemotaxis)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035329"(hippo signaling)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q4VCS5|rcsb pdb:6JJX|reactome:R-HSA-2028269|refseq:XP_011529177.1|refseq:NP_001106962.1|refseq:NP_573572.1|refseq:XP_005262144.1|refseq:XP_005262147.1|refseq:XP_016884778.1|dip:DIP-53711N refseq:NP_001287936.1|refseq:NP_570899.1|ensembl:ENST00000317829|ensembl:ENSP00000320968|ensembl:ENSP00000387739|ensembl:ENSG00000166025(gene)|ensembl:ENST00000433060(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035329"(hippo signaling)|go:"GO:0042802"(identical protein binding)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q8IY63|reactome:R-HSA-2028269|dip:DIP-50682N - - comment:"author score: 49" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5O9K+GgX1s0Hn5optTeKPOs+X1s9606 rogid:yveF+96pkmFC0XntrVNmwhrVzK09606 rigid:OgxuVh1oQ6vzhM6VpmZl4z5gOFk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99856 uniprotkb:P60174 intact:EBI-5458244|uniprotkb:Q5I858|uniprotkb:Q6P9C6|uniprotkb:Q8IZA7|uniprotkb:Q8N4Z3|ensembl:ENSP00000263620 intact:EBI-717475|uniprotkb:D3DUS9|uniprotkb:P00938|uniprotkb:Q6IS07|uniprotkb:Q8WWD0|uniprotkb:Q96AG5|uniprotkb:Q6FHP9|uniprotkb:B7Z5D8|ensembl:ENSP00000379933 psi-mi:ari3a_human(display_long)|uniprotkb:ARID3A(gene name)|psi-mi:ARID3A(display_short)|uniprotkb:DRIL1(gene name synonym)|uniprotkb:DRIL3(gene name synonym)|uniprotkb:DRX(gene name synonym)|uniprotkb:E2FBP1(gene name synonym)|uniprotkb:B-cell regulator of IgH transcription(gene name synonym)|uniprotkb:Dead ringer-like protein 1(gene name synonym)|uniprotkb:E2F-binding protein 1(gene name synonym) psi-mi:tpis_human(display_long)|uniprotkb:Triose-phosphate isomerase(gene name synonym)|uniprotkb:TPI1(gene name)|psi-mi:TPI1(display_short)|uniprotkb:TPI(gene name synonym)|uniprotkb:Methylglyoxal synthase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476013|imex:IM-26985-143 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005215.1|refseq:XP_005259570.1|refseq:XP_005259571.1|refseq:XP_016881934.1|ensembl:ENSG00000116017(gene)|ensembl:ENST00000263620(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR023334|interpro:IPR036431|mint:Q99856|rcsb pdb:2KK0|rcsb pdb:4LJX|reactome:R-HSA-6804116 refseq:NP_000356.1|refseq:NP_001152759.1|refseq:NP_001244955.1|ensembl:ENSG00000111669(gene)|ensembl:ENST00000396705(transcript)|go:"GO:0004807"(triose-phosphate isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0008929"(methylglyoxal synthase activity)|go:"GO:0019242"(methylglyoxal biosynthetic process)|go:"GO:0019563"(glycerol catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046166"(glyceraldehyde-3-phosphate biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000652(Triosephosphate isomerase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR020861|interpro:IPR022896|interpro:IPR035990|mint:P60174|rcsb pdb:1HTI|rcsb pdb:1KLG|rcsb pdb:1KLU|rcsb pdb:1WYI|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2JK2|rcsb pdb:2VOM|rcsb pdb:4BR1|rcsb pdb:4E41|rcsb pdb:4POC|rcsb pdb:4POD|rcsb pdb:4UNK|rcsb pdb:4UNL|rcsb pdb:4ZVJ|rcsb pdb:6C2G|rcsb pdb:6D43|rcsb pdb:6NLH|rcsb pdb:6UP1|rcsb pdb:6UP5|rcsb pdb:6UP8|rcsb pdb:6UPF|reactome:R-HSA-70171|reactome:R-HSA-70263 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:OovnBk28KzvFoKdJICElQQRBKH49606 rogid:FaLt6wGI1Bz2Z81gX35p7sOiMbE9606 rigid:eg1CqwqboKP7Thq4+HPfisxl9tY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99856 uniprotkb:Q07955 intact:EBI-5458244|uniprotkb:Q5I858|uniprotkb:Q6P9C6|uniprotkb:Q8IZA7|uniprotkb:Q8N4Z3|ensembl:ENSP00000263620 intact:EBI-398920|uniprotkb:Q13809|uniprotkb:B2R6Z7|uniprotkb:D3DTZ3|ensembl:ENSP00000258962 psi-mi:ari3a_human(display_long)|uniprotkb:ARID3A(gene name)|psi-mi:ARID3A(display_short)|uniprotkb:DRIL1(gene name synonym)|uniprotkb:DRIL3(gene name synonym)|uniprotkb:DRX(gene name synonym)|uniprotkb:E2FBP1(gene name synonym)|uniprotkb:B-cell regulator of IgH transcription(gene name synonym)|uniprotkb:Dead ringer-like protein 1(gene name synonym)|uniprotkb:E2F-binding protein 1(gene name synonym) psi-mi:srsf1_human(display_long)|uniprotkb:SF2(gene name synonym)|uniprotkb:SF2P33(gene name synonym)|uniprotkb:OK/SW-cl.3(orf name)|uniprotkb:SRSF1(gene name)|psi-mi:SRSF1(display_short)|uniprotkb:ASF(gene name synonym)|uniprotkb:pre-mRNA-splicing factor SF2, P33 subunit(gene name synonym)|uniprotkb:Alternative-splicing factor 1(gene name synonym)|uniprotkb:SFRS1(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476013|imex:IM-26985-143 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005215.1|refseq:XP_005259570.1|refseq:XP_005259571.1|refseq:XP_016881934.1|ensembl:ENSG00000116017(gene)|ensembl:ENST00000263620(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR023334|interpro:IPR036431|mint:Q99856|rcsb pdb:2KK0|rcsb pdb:4LJX|reactome:R-HSA-6804116 refseq:NP_001071634.1|refseq:NP_008855.1|dip:DIP-2155N|ensembl:ENSG00000136450(gene)|ensembl:ENST00000258962(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0051028"(mRNA transport)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097421"(liver regeneration)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034520|interpro:IPR035979|mint:Q07955|rcsb pdb:2M7S|rcsb pdb:2M8D|rcsb pdb:2O3D|rcsb pdb:3BEG|rcsb pdb:4C0O|rcsb pdb:6HPJ|rcsb pdb:7ABG|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:1X4A - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:OovnBk28KzvFoKdJICElQQRBKH49606 rogid:6/IA4a3btkfSBtMH32iCe+rqZ8Y9606 rigid:eg1CqwqboKP7Thq4+HPfisxl9tY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99856 uniprotkb:P12277 intact:EBI-5458244|uniprotkb:Q5I858|uniprotkb:Q6P9C6|uniprotkb:Q8IZA7|uniprotkb:Q8N4Z3|ensembl:ENSP00000263620 intact:EBI-357706|uniprotkb:Q2LE07|uniprotkb:A8K236|uniprotkb:B2R5R4|uniprotkb:Q6FG40|uniprotkb:Q9UC66|ensembl:ENSP00000299198 psi-mi:ari3a_human(display_long)|uniprotkb:ARID3A(gene name)|psi-mi:ARID3A(display_short)|uniprotkb:DRIL1(gene name synonym)|uniprotkb:DRIL3(gene name synonym)|uniprotkb:DRX(gene name synonym)|uniprotkb:E2FBP1(gene name synonym)|uniprotkb:B-cell regulator of IgH transcription(gene name synonym)|uniprotkb:Dead ringer-like protein 1(gene name synonym)|uniprotkb:E2F-binding protein 1(gene name synonym) psi-mi:kcrb_human(display_long)|uniprotkb:CKB(gene name)|psi-mi:CKB(display_short)|uniprotkb:CKBB(gene name synonym)|uniprotkb:Creatine kinase B chain(gene name synonym)|uniprotkb:Brain creatine kinase(gene name synonym)|uniprotkb:Creatine phosphokinase B-type(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476013|imex:IM-26985-143 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005215.1|refseq:XP_005259570.1|refseq:XP_005259571.1|refseq:XP_016881934.1|ensembl:ENSG00000116017(gene)|ensembl:ENST00000263620(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR023334|interpro:IPR036431|mint:Q99856|rcsb pdb:2KK0|rcsb pdb:4LJX|reactome:R-HSA-6804116 refseq:NP_001814.2|go:"GO:0005829"(cytosol)|ensembl:ENSG00000166165(gene)|ensembl:ENST00000348956(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0016301"(kinase activity)|go:"GO:0021549"(cerebellum development)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:P12277|rcsb pdb:3B6R|rcsb pdb:3DRB|rcsb pdb:3DRE|rcsb pdb:6V9H|go:"GO:0021762"(substantia nigra development)|go:"GO:0030425"(dendrite)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046314"(phosphocreatine biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|reactome:R-HSA-71288|reactome:R-HSA-9696264|dip:DIP-52968N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:OovnBk28KzvFoKdJICElQQRBKH49606 rogid:WLRnU8sRUfJQoaPY0edGi9xiR+g9606 rigid:eg1CqwqboKP7Thq4+HPfisxl9tY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99856 uniprotkb:Q9NQ29 intact:EBI-5458244|uniprotkb:Q5I858|uniprotkb:Q6P9C6|uniprotkb:Q8IZA7|uniprotkb:Q8N4Z3|ensembl:ENSP00000263620 intact:EBI-473747|uniprotkb:Q96S32|uniprotkb:Q9NPH4|uniprotkb:B8ZZ13|ensembl:ENSP00000293872 psi-mi:ari3a_human(display_long)|uniprotkb:ARID3A(gene name)|psi-mi:ARID3A(display_short)|uniprotkb:DRIL1(gene name synonym)|uniprotkb:DRIL3(gene name synonym)|uniprotkb:DRX(gene name synonym)|uniprotkb:E2FBP1(gene name synonym)|uniprotkb:B-cell regulator of IgH transcription(gene name synonym)|uniprotkb:Dead ringer-like protein 1(gene name synonym)|uniprotkb:E2F-binding protein 1(gene name synonym) psi-mi:luc7l_human(display_long)|uniprotkb:SR+89(gene name synonym)|uniprotkb:Putative SR protein LUC7B1(gene name synonym)|uniprotkb:LUC7L(gene name)|psi-mi:LUC7L(display_short)|uniprotkb:LUC7L1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476013|imex:IM-26985-143 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005215.1|refseq:XP_005259570.1|refseq:XP_005259571.1|refseq:XP_016881934.1|ensembl:ENSG00000116017(gene)|ensembl:ENST00000263620(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR023334|interpro:IPR036431|mint:Q99856|rcsb pdb:2KK0|rcsb pdb:4LJX|reactome:R-HSA-6804116 refseq:NP_001307155.1|refseq:NP_001317349.1|refseq:NP_060502.1|refseq:NP_958815.1|ensembl:ENSG00000007392(gene)|ensembl:ENST00000293872(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005685"(U1 snRNP)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0042802"(identical protein binding)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR004882(LUC7 related)|mint:Q9NQ29 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:OovnBk28KzvFoKdJICElQQRBKH49606 rogid:Hsl0VZTCTP6UrKlo/FHOVwZqCaw9606 rigid:eg1CqwqboKP7Thq4+HPfisxl9tY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99856 uniprotkb:P06454 intact:EBI-5458244|uniprotkb:Q5I858|uniprotkb:Q6P9C6|uniprotkb:Q8IZA7|uniprotkb:Q8N4Z3|ensembl:ENSP00000263620 intact:EBI-2682091|uniprotkb:Q15249|uniprotkb:Q15592|ensembl:ENSP00000344547 psi-mi:ari3a_human(display_long)|uniprotkb:ARID3A(gene name)|psi-mi:ARID3A(display_short)|uniprotkb:DRIL1(gene name synonym)|uniprotkb:DRIL3(gene name synonym)|uniprotkb:DRX(gene name synonym)|uniprotkb:E2FBP1(gene name synonym)|uniprotkb:B-cell regulator of IgH transcription(gene name synonym)|uniprotkb:Dead ringer-like protein 1(gene name synonym)|uniprotkb:E2F-binding protein 1(gene name synonym) psi-mi:ptma_human(display_long)|uniprotkb:TMSA(gene name synonym)|uniprotkb:PTMA(gene name)|psi-mi:PTMA(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476013|imex:IM-26985-143 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005215.1|refseq:XP_005259570.1|refseq:XP_005259571.1|refseq:XP_016881934.1|ensembl:ENSG00000116017(gene)|ensembl:ENST00000263620(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR023334|interpro:IPR036431|mint:Q99856|rcsb pdb:2KK0|rcsb pdb:4LJX|reactome:R-HSA-6804116 refseq:NP_001092755.1|refseq:NP_002814.3|ensembl:ENSG00000187514(gene)|ensembl:ENST00000341369(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR004931(Prothymosin/parathymosin)|mint:P06454|rcsb pdb:2L9I|rcsb pdb:2MNQ|dip:DIP-40743N - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:OovnBk28KzvFoKdJICElQQRBKH49606 rogid:scRCSTJyl5e12uNhBR+L4CKQ6Ac9606 rigid:eg1CqwqboKP7Thq4+HPfisxl9tY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99856 uniprotkb:Q13126 intact:EBI-5458244|uniprotkb:Q5I858|uniprotkb:Q6P9C6|uniprotkb:Q8IZA7|uniprotkb:Q8N4Z3|ensembl:ENSP00000263620 intact:EBI-2547776|ensembl:ENSP00000494373|uniprotkb:Q5T3P3|uniprotkb:Q9H010|uniprotkb:I2G7M5|uniprotkb:I2G7M6|uniprotkb:I2G7M7|uniprotkb:I2G7M8|uniprotkb:I2G7M9|uniprotkb:I2G7N0 psi-mi:ari3a_human(display_long)|uniprotkb:ARID3A(gene name)|psi-mi:ARID3A(display_short)|uniprotkb:DRIL1(gene name synonym)|uniprotkb:DRIL3(gene name synonym)|uniprotkb:DRX(gene name synonym)|uniprotkb:E2FBP1(gene name synonym)|uniprotkb:B-cell regulator of IgH transcription(gene name synonym)|uniprotkb:Dead ringer-like protein 1(gene name synonym)|uniprotkb:E2F-binding protein 1(gene name synonym) psi-mi:mtap_human(display_long)|uniprotkb:MTAP(gene name)|psi-mi:MTAP(display_short)|uniprotkb:MSAP(gene name synonym)|uniprotkb:5'-methylthioadenosine phosphorylase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476013|imex:IM-26985-143 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005215.1|refseq:XP_005259570.1|refseq:XP_005259571.1|refseq:XP_016881934.1|ensembl:ENSG00000116017(gene)|ensembl:ENST00000263620(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR023334|interpro:IPR036431|mint:Q99856|rcsb pdb:2KK0|rcsb pdb:4LJX|reactome:R-HSA-6804116 ensembl:ENSG00000099810(gene)|ensembl:ENST00000644715(transcript)|go:"GO:0004645"(1,4-alpha-oligoglucan phosphorylase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0019509"(L-methionine salvage from methylthioadenosine)|go:"GO:0032259"(methylation)|go:"GO:0033574"(response to testosterone)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:5EUB|rcsb pdb:5TC5|rcsb pdb:5TC6|rcsb pdb:5TC7|rcsb pdb:5TC8|rcsb pdb:6DYZ|rcsb pdb:6DZ0|rcsb pdb:6DZ2|rcsb pdb:6DZ3|reactome:R-HSA-1237112|reactome:R-HSA-8950505|interpro:IPR000845(Nucleoside phosphorylase)|interpro:IPR010044(Methylthioadenosine phosphorylase)|interpro:IPR018099|interpro:IPR035994|mint:Q13126|rcsb pdb:1CB0|rcsb pdb:1CG6|rcsb pdb:1K27|rcsb pdb:1SD1|rcsb pdb:1SD2|rcsb pdb:3LN5|rcsb pdb:3OZC|rcsb pdb:3OZD|rcsb pdb:3OZE|refseq:NP_002442.2 - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:OovnBk28KzvFoKdJICElQQRBKH49606 rogid:YQYb6o+mNKPtlSdUKveEOo7fpHE9606 rigid:eg1CqwqboKP7Thq4+HPfisxl9tY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99856 uniprotkb:P61604 intact:EBI-5458244|uniprotkb:Q5I858|uniprotkb:Q6P9C6|uniprotkb:Q8IZA7|uniprotkb:Q8N4Z3|ensembl:ENSP00000263620 intact:EBI-711483|uniprotkb:O95421|uniprotkb:Q04984|uniprotkb:Q53X54|ensembl:ENSP00000233893|uniprotkb:Q9UDH0 psi-mi:ari3a_human(display_long)|uniprotkb:ARID3A(gene name)|psi-mi:ARID3A(display_short)|uniprotkb:DRIL1(gene name synonym)|uniprotkb:DRIL3(gene name synonym)|uniprotkb:DRX(gene name synonym)|uniprotkb:E2FBP1(gene name synonym)|uniprotkb:B-cell regulator of IgH transcription(gene name synonym)|uniprotkb:Dead ringer-like protein 1(gene name synonym)|uniprotkb:E2F-binding protein 1(gene name synonym) psi-mi:ch10_human(display_long)|uniprotkb:HSPE1(gene name)|psi-mi:HSPE1(display_short)|uniprotkb:10 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 10(gene name synonym)|uniprotkb:Early-pregnancy factor(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476013|imex:IM-26985-143 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005215.1|refseq:XP_005259570.1|refseq:XP_005259571.1|refseq:XP_016881934.1|ensembl:ENSG00000116017(gene)|ensembl:ENST00000263620(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR023334|interpro:IPR036431|mint:Q99856|rcsb pdb:2KK0|rcsb pdb:4LJX|reactome:R-HSA-6804116 interpro:IPR020818|interpro:IPR037124|mint:P61604|rcsb pdb:4PJ1|rcsb pdb:6HT7|rcsb pdb:6MRC|rcsb pdb:6MRD|reactome:R-HSA-9013408|ensembl:ENSG00000115541(gene)|ensembl:ENST00000233893(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR011032(GroES-like)|interpro:IPR018369|refseq:NP_002148.1 - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:OovnBk28KzvFoKdJICElQQRBKH49606 rogid:BmnGoMnA2QIr3Dr0fElMtTgRztA9606 rigid:eg1CqwqboKP7Thq4+HPfisxl9tY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99856 uniprotkb:P27695 intact:EBI-5458244|uniprotkb:Q5I858|uniprotkb:Q6P9C6|uniprotkb:Q8IZA7|uniprotkb:Q8N4Z3|ensembl:ENSP00000263620 intact:EBI-1048805|uniprotkb:Q969L5|uniprotkb:Q99775|ensembl:ENSP00000216714|ensembl:ENSP00000381111|ensembl:ENSP00000451979 psi-mi:ari3a_human(display_long)|uniprotkb:ARID3A(gene name)|psi-mi:ARID3A(display_short)|uniprotkb:DRIL1(gene name synonym)|uniprotkb:DRIL3(gene name synonym)|uniprotkb:DRX(gene name synonym)|uniprotkb:E2FBP1(gene name synonym)|uniprotkb:B-cell regulator of IgH transcription(gene name synonym)|uniprotkb:Dead ringer-like protein 1(gene name synonym)|uniprotkb:E2F-binding protein 1(gene name synonym) psi-mi:apex1_human(display_long)|uniprotkb:Apurinic-apyrimidinic endonuclease 1(gene name synonym)|uniprotkb:APEX nuclease(gene name synonym)|uniprotkb:APE1(gene name synonym)|uniprotkb:APEX1(gene name)|psi-mi:APEX1(display_short)|uniprotkb:APE(gene name synonym)|uniprotkb:APEX(gene name synonym)|uniprotkb:APX(gene name synonym)|uniprotkb:HAP1(gene name synonym)|uniprotkb:REF1(gene name synonym)|uniprotkb:REF-1(gene name synonym)|uniprotkb:Redox factor-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476013|imex:IM-26985-143 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005215.1|refseq:XP_005259570.1|refseq:XP_005259571.1|refseq:XP_016881934.1|ensembl:ENSG00000116017(gene)|ensembl:ENST00000263620(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR023334|interpro:IPR036431|mint:Q99856|rcsb pdb:2KK0|rcsb pdb:4LJX|reactome:R-HSA-6804116 refseq:NP_001632.2|refseq:NP_542379.1|refseq:NP_542380.1|refseq:NP_001231178.1|ensembl:ENSG00000100823(gene)|ensembl:ENST00000216714(transcript)|ensembl:ENST00000398030(transcript)|ensembl:ENST00000555414(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004519"(endonuclease activity)|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0004528"(phosphodiesterase I activity)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005840"(ribosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006310"(DNA recombination)|go:"GO:0007568"(aging)|go:"GO:0008081"(phosphoric diester hydrolase activity)|go:"GO:0008309"(double-stranded DNA exodeoxyribonuclease activity)|go:"GO:0008311"(double-stranded DNA 3'-5' exodeoxyribonuclease activity)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0016890"(site-specific endodeoxyribonuclease activity, specific for altered base)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042493"|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0080111"(DNA demethylation)|go:"GO:0097698"(telomere maintenance via base-excision repair)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR004808(Exodeoxyribonuclease III xth)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR020847|interpro:IPR020848|interpro:IPR036691|mint:P27695|rcsb pdb:1BIX|rcsb pdb:1CQG|rcsb pdb:1CQH|rcsb pdb:1DE8|rcsb pdb:1DE9|rcsb pdb:1DEW|rcsb pdb:1E9N|rcsb pdb:1HD7|rcsb pdb:2ISI|rcsb pdb:2O3H|rcsb pdb:3U8U|rcsb pdb:4IEM|rcsb pdb:4LND|rcsb pdb:4QH9|rcsb pdb:4QHD|rcsb pdb:4QHE|rcsb pdb:5CFG|rcsb pdb:5DFF|rcsb pdb:5DFH|rcsb pdb:5DFI|rcsb pdb:5DFJ|rcsb pdb:5DG0|rcsb pdb:5WN0|rcsb pdb:5WN1|rcsb pdb:5WN2|rcsb pdb:5WN3|rcsb pdb:5WN4|rcsb pdb:5WN5|rcsb pdb:6BOQ|rcsb pdb:6BOR|rcsb pdb:6BOS|rcsb pdb:6BOT|rcsb pdb:6BOU|rcsb pdb:6BOV|rcsb pdb:6BOW|rcsb pdb:6MK3|rcsb pdb:6MKK|rcsb pdb:6MKM|rcsb pdb:6MKO|rcsb pdb:6P93|rcsb pdb:6P94|rcsb pdb:6W0Q|rcsb pdb:6W2P|rcsb pdb:6W3L|rcsb pdb:6W3N|rcsb pdb:6W3Q|rcsb pdb:6W3U|rcsb pdb:6W43|rcsb pdb:6W4I|rcsb pdb:6W4T|reactome:R-HSA-110357|reactome:R-HSA-110362|reactome:R-HSA-110373|reactome:R-HSA-5651801|reactome:R-HSA-73930|reactome:R-HSA-73933|dip:DIP-6130N - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:OovnBk28KzvFoKdJICElQQRBKH49606 rogid:418z7Qhlcop0UKIfNQse+iyM8gg9606 rigid:eg1CqwqboKP7Thq4+HPfisxl9tY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99856 uniprotkb:Q8IVW6 intact:EBI-5458244|uniprotkb:Q5I858|uniprotkb:Q6P9C6|uniprotkb:Q8IZA7|uniprotkb:Q8N4Z3|ensembl:ENSP00000263620 intact:EBI-5458329|uniprotkb:O95443|uniprotkb:Q59HC9|uniprotkb:Q6P9C9|ensembl:ENSP00000477878 psi-mi:ari3a_human(display_long)|uniprotkb:ARID3A(gene name)|psi-mi:ARID3A(display_short)|uniprotkb:DRIL1(gene name synonym)|uniprotkb:DRIL3(gene name synonym)|uniprotkb:DRX(gene name synonym)|uniprotkb:E2FBP1(gene name synonym)|uniprotkb:B-cell regulator of IgH transcription(gene name synonym)|uniprotkb:Dead ringer-like protein 1(gene name synonym)|uniprotkb:E2F-binding protein 1(gene name synonym) psi-mi:ari3b_human(display_long)|uniprotkb:ARID3B(gene name)|psi-mi:ARID3B(display_short)|uniprotkb:BDP(gene name synonym)|uniprotkb:DRIL2(gene name synonym)|uniprotkb:Bright and dead ringer protein(gene name synonym)|uniprotkb:Bright-like protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476013|imex:IM-26985-143 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005215.1|refseq:XP_005259570.1|refseq:XP_005259571.1|refseq:XP_016881934.1|ensembl:ENSG00000116017(gene)|ensembl:ENST00000263620(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR023334|interpro:IPR036431|mint:Q99856|rcsb pdb:2KK0|rcsb pdb:4LJX|reactome:R-HSA-6804116 refseq:NP_001294868.1|refseq:NP_006456.1|ensembl:ENSG00000179361(gene)|ensembl:ENST00000622429(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR023334|mint:Q8IVW6|interpro:IPR036431 - - comment:"author score: 71" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:OovnBk28KzvFoKdJICElQQRBKH49606 rogid:wlZYnH9qjM7VzFUtrNLlqJhRXx49606 rigid:eg1CqwqboKP7Thq4+HPfisxl9tY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q03989 uniprotkb:P49189 intact:EBI-948603|ensembl:ENSP00000350078|intact:EBI-10176351|intact:EBI-15316505|uniprotkb:C9J1Q0|uniprotkb:Q6NX37 intact:EBI-1055313|uniprotkb:B2R6X1|uniprotkb:Q6LCL1|uniprotkb:Q9NZT7|uniprotkb:Q5VV90|uniprotkb:B4DXY7|uniprotkb:B9EKV4 psi-mi:ari5a_human(display_long)|uniprotkb:Modulator recognition factor 1(gene name synonym)|uniprotkb:ARID5A(gene name)|psi-mi:ARID5A(display_short)|uniprotkb:MRF1(gene name synonym) psi-mi:al9a1_human(display_long)|uniprotkb:Aldehyde dehydrogenase family 9 member A1(gene name synonym)|uniprotkb:Aldehyde dehydrogenase E3 isozyme(gene name synonym)|uniprotkb:Gamma-aminobutyraldehyde dehydrogenase(gene name synonym)|uniprotkb:R-aminobutyraldehyde dehydrogenase(gene name synonym)|uniprotkb:ALDH9A1(gene name)|psi-mi:ALDH9A1(display_short)|uniprotkb:ALDH7(gene name synonym)|uniprotkb:ALDH9(gene name synonym)|uniprotkb:ALDH4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476046|imex:IM-26985-525 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196843(gene)|ensembl:ENST00000357485(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR036431|mint:Q03989|uniprotkb:Q03989-2(uniprot-removed-ac)|refseq:NP_997646.1|refseq:NP_001306021.1 refseq:NP_000687.3|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR015590(Aldehyde dehydrogenase)|refseq:XP_011507596.1|interpro:IPR029510|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006081"(cellular aldehyde metabolic process)|go:"GO:0019145"(aminobutyraldehyde dehydrogenase activity)|go:"GO:0033737"(1-pyrroline dehydrogenase activity)|go:"GO:0042136"(neurotransmitter biosynthetic process)|go:"GO:0042445"(hormone metabolic process)|go:"GO:0043878"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity")|go:"GO:0045329"(carnitine biosynthetic process)|go:"GO:0047105"(4-trimethylammoniobutyraldehyde dehydrogenase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:6QAK|rcsb pdb:6QAO|rcsb pdb:6QAP|rcsb pdb:6VR6|rcsb pdb:6VWF|reactome:R-HSA-71262|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|mint:P49189 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Zi6YxDBLmiIe852L2PlAAdCj7Dg9606 rogid:MYde00UETppWGSEKa35Jsck7Joc9606 rigid:ceW1vrSoxZhUftrK7QgbBmM0h18 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q03989 uniprotkb:P61962 intact:EBI-948603|ensembl:ENSP00000350078|intact:EBI-10176351|intact:EBI-15316505|uniprotkb:C9J1Q0|uniprotkb:Q6NX37 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 psi-mi:ari5a_human(display_long)|uniprotkb:Modulator recognition factor 1(gene name synonym)|uniprotkb:ARID5A(gene name)|psi-mi:ARID5A(display_short)|uniprotkb:MRF1(gene name synonym) psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476046|imex:IM-26985-525 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196843(gene)|ensembl:ENST00000357485(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR036431|mint:Q03989|uniprotkb:Q03989-2(uniprot-removed-ac)|refseq:NP_997646.1|refseq:NP_001306021.1 refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Zi6YxDBLmiIe852L2PlAAdCj7Dg9606 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 rigid:ceW1vrSoxZhUftrK7QgbBmM0h18 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7Z2E3 uniprotkb:Q9HAF1 intact:EBI-847814|uniprotkb:A8MTN4|uniprotkb:Q5T781|uniprotkb:Q7Z2F3|uniprotkb:Q7Z336|uniprotkb:Q7Z5R5|uniprotkb:Q7Z6V7|uniprotkb:Q7Z6V8|uniprotkb:Q9NXM5|uniprotkb:Q0P662|uniprotkb:Q5T784|uniprotkb:D3DRK9|uniprotkb:D3DRL0|uniprotkb:Q5T782|uniprotkb:Q6JV81|uniprotkb:Q6JV82|uniprotkb:Q6JV85 intact:EBI-399266|uniprotkb:B1AK64|uniprotkb:Q4F967|uniprotkb:Q7Z311|uniprotkb:Q86WE3|ensembl:ENSP00000296214 psi-mi:aptx_human(display_long)|uniprotkb:Forkhead-associated domain histidine triad-like protein(gene name synonym)|uniprotkb:APTX(gene name)|psi-mi:APTX(display_short)|uniprotkb:AXA1(gene name synonym) psi-mi:eaf6_human(display_long)|uniprotkb:Sarcoma antigen NY-SAR-91(gene name synonym)|uniprotkb:MEAF6(gene name)|psi-mi:MEAF6(display_short)|uniprotkb:EAF6(gene name synonym)|uniprotkb:Esa1-associated factor 6 homolog(gene name synonym)|uniprotkb:C1orf149(gene name synonym)|uniprotkb:CENP-28(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25475998|imex:IM-26985-523 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006716854.1|refseq:XP_006716855.1|refseq:NP_001182177.1|refseq:NP_001182178.1|refseq:NP_001182179.1|refseq:NP_001182180.1|refseq:NP_001182181.1|refseq:NP_001182183.1|refseq:NP_778239.1|refseq:NP_778243.1|interpro:IPR000253(Forkhead-associated)|interpro:IPR011146(Histidine triad-like motif)|interpro:IPR019808|interpro:IPR008984(SMAD/FHA domain)|refseq:XP_016870326.1|interpro:IPR026963|interpro:IPR032566|interpro:IPR036265|refseq:XP_011516240.1|refseq:XP_011516241.1|mint:Q7Z2E3|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR041388|go:"GO:0000012"(single strand break repair)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006266"(DNA ligation)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008967"(phosphoglycolate phosphatase activity)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033699"(DNA 5'-adenosine monophosphate hydrolase activity)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0046403"(polynucleotide 3'-phosphatase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0120108"(DNA-3'-diphospho-5'-guanosine diphosphatase)|go:"GO:1990165"(single-strand break-containing DNA binding)|rcsb pdb:3KT9|rcsb pdb:4NDF|rcsb pdb:4NDG|rcsb pdb:4NDH|rcsb pdb:4NDI|rcsb pdb:6CVO|rcsb pdb:6CVP|rcsb pdb:6CVQ|rcsb pdb:6CVR|rcsb pdb:6CVS|rcsb pdb:6CVT refseq:NP_001257804.1|refseq:NP_073593.2|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|go:"GO:1990467"(NuA3a histone acetyltransferase complex)|go:"GO:1990468"(NuA3b histone acetyltransferase complex)|interpro:IPR015418(Histone H4 acetyltransferase, NuA4 complex, Eaf6)|mint:Q9HAF1|reactome:R-HSA-3214847|reactome:R-HSA-6804758|ensembl:ENSG00000163875(gene)|ensembl:ENST00000296214(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|refseq:NP_001257805.1 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+F8ouBUeaA4oDe1S6zOGADQfCxQ9606 rogid:v0eU3uwnLihcUQhLKYma3WIhofk9606 rigid:0ay/u7hXY8EQ9QH9wdvaX8Mc4Tw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7Z2E3 uniprotkb:P61604 intact:EBI-847814|uniprotkb:A8MTN4|uniprotkb:Q5T781|uniprotkb:Q7Z2F3|uniprotkb:Q7Z336|uniprotkb:Q7Z5R5|uniprotkb:Q7Z6V7|uniprotkb:Q7Z6V8|uniprotkb:Q9NXM5|uniprotkb:Q0P662|uniprotkb:Q5T784|uniprotkb:D3DRK9|uniprotkb:D3DRL0|uniprotkb:Q5T782|uniprotkb:Q6JV81|uniprotkb:Q6JV82|uniprotkb:Q6JV85 intact:EBI-711483|uniprotkb:O95421|uniprotkb:Q04984|uniprotkb:Q53X54|ensembl:ENSP00000233893|uniprotkb:Q9UDH0 psi-mi:aptx_human(display_long)|uniprotkb:Forkhead-associated domain histidine triad-like protein(gene name synonym)|uniprotkb:APTX(gene name)|psi-mi:APTX(display_short)|uniprotkb:AXA1(gene name synonym) psi-mi:ch10_human(display_long)|uniprotkb:HSPE1(gene name)|psi-mi:HSPE1(display_short)|uniprotkb:10 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 10(gene name synonym)|uniprotkb:Early-pregnancy factor(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25475998|imex:IM-26985-523 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006716854.1|refseq:XP_006716855.1|refseq:NP_001182177.1|refseq:NP_001182178.1|refseq:NP_001182179.1|refseq:NP_001182180.1|refseq:NP_001182181.1|refseq:NP_001182183.1|refseq:NP_778239.1|refseq:NP_778243.1|interpro:IPR000253(Forkhead-associated)|interpro:IPR011146(Histidine triad-like motif)|interpro:IPR019808|interpro:IPR008984(SMAD/FHA domain)|refseq:XP_016870326.1|interpro:IPR026963|interpro:IPR032566|interpro:IPR036265|refseq:XP_011516240.1|refseq:XP_011516241.1|mint:Q7Z2E3|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR041388|go:"GO:0000012"(single strand break repair)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006266"(DNA ligation)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008967"(phosphoglycolate phosphatase activity)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033699"(DNA 5'-adenosine monophosphate hydrolase activity)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0046403"(polynucleotide 3'-phosphatase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0120108"(DNA-3'-diphospho-5'-guanosine diphosphatase)|go:"GO:1990165"(single-strand break-containing DNA binding)|rcsb pdb:3KT9|rcsb pdb:4NDF|rcsb pdb:4NDG|rcsb pdb:4NDH|rcsb pdb:4NDI|rcsb pdb:6CVO|rcsb pdb:6CVP|rcsb pdb:6CVQ|rcsb pdb:6CVR|rcsb pdb:6CVS|rcsb pdb:6CVT interpro:IPR020818|interpro:IPR037124|mint:P61604|rcsb pdb:4PJ1|rcsb pdb:6HT7|rcsb pdb:6MRC|rcsb pdb:6MRD|reactome:R-HSA-9013408|ensembl:ENSG00000115541(gene)|ensembl:ENST00000233893(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR011032(GroES-like)|interpro:IPR018369|refseq:NP_002148.1 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+F8ouBUeaA4oDe1S6zOGADQfCxQ9606 rogid:BmnGoMnA2QIr3Dr0fElMtTgRztA9606 rigid:0ay/u7hXY8EQ9QH9wdvaX8Mc4Tw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7Z2E3 uniprotkb:P06454 intact:EBI-847814|uniprotkb:A8MTN4|uniprotkb:Q5T781|uniprotkb:Q7Z2F3|uniprotkb:Q7Z336|uniprotkb:Q7Z5R5|uniprotkb:Q7Z6V7|uniprotkb:Q7Z6V8|uniprotkb:Q9NXM5|uniprotkb:Q0P662|uniprotkb:Q5T784|uniprotkb:D3DRK9|uniprotkb:D3DRL0|uniprotkb:Q5T782|uniprotkb:Q6JV81|uniprotkb:Q6JV82|uniprotkb:Q6JV85 intact:EBI-2682091|uniprotkb:Q15249|uniprotkb:Q15592|ensembl:ENSP00000344547 psi-mi:aptx_human(display_long)|uniprotkb:Forkhead-associated domain histidine triad-like protein(gene name synonym)|uniprotkb:APTX(gene name)|psi-mi:APTX(display_short)|uniprotkb:AXA1(gene name synonym) psi-mi:ptma_human(display_long)|uniprotkb:TMSA(gene name synonym)|uniprotkb:PTMA(gene name)|psi-mi:PTMA(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25475998|imex:IM-26985-523 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006716854.1|refseq:XP_006716855.1|refseq:NP_001182177.1|refseq:NP_001182178.1|refseq:NP_001182179.1|refseq:NP_001182180.1|refseq:NP_001182181.1|refseq:NP_001182183.1|refseq:NP_778239.1|refseq:NP_778243.1|interpro:IPR000253(Forkhead-associated)|interpro:IPR011146(Histidine triad-like motif)|interpro:IPR019808|interpro:IPR008984(SMAD/FHA domain)|refseq:XP_016870326.1|interpro:IPR026963|interpro:IPR032566|interpro:IPR036265|refseq:XP_011516240.1|refseq:XP_011516241.1|mint:Q7Z2E3|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR041388|go:"GO:0000012"(single strand break repair)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006266"(DNA ligation)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008967"(phosphoglycolate phosphatase activity)|go:"GO:0030983"(mismatched DNA binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033699"(DNA 5'-adenosine monophosphate hydrolase activity)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0046403"(polynucleotide 3'-phosphatase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0120108"(DNA-3'-diphospho-5'-guanosine diphosphatase)|go:"GO:1990165"(single-strand break-containing DNA binding)|rcsb pdb:3KT9|rcsb pdb:4NDF|rcsb pdb:4NDG|rcsb pdb:4NDH|rcsb pdb:4NDI|rcsb pdb:6CVO|rcsb pdb:6CVP|rcsb pdb:6CVQ|rcsb pdb:6CVR|rcsb pdb:6CVS|rcsb pdb:6CVT refseq:NP_001092755.1|refseq:NP_002814.3|ensembl:ENSG00000187514(gene)|ensembl:ENST00000341369(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR004931(Prothymosin/parathymosin)|mint:P06454|rcsb pdb:2L9I|rcsb pdb:2MNQ|dip:DIP-40743N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+F8ouBUeaA4oDe1S6zOGADQfCxQ9606 rogid:scRCSTJyl5e12uNhBR+L4CKQ6Ac9606 rigid:0ay/u7hXY8EQ9QH9wdvaX8Mc4Tw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15511 uniprotkb:Q8N3C0 intact:EBI-352975|uniprotkb:A6NEC4|uniprotkb:Q6PG42|ensembl:ENSP00000352918 intact:EBI-1210710|uniprotkb:Q9NTR0|uniprotkb:O43738|uniprotkb:Q5VTN2|uniprotkb:Q9H1I9|uniprotkb:E7EW23|uniprotkb:Q4G1A0|uniprotkb:Q9H5A2|ensembl:ENSP00000358159 psi-mi:arpc5_human(display_long)|uniprotkb:ARPC5(gene name)|psi-mi:ARPC5(display_short)|uniprotkb:ARC16(gene name synonym)|uniprotkb:Arp2/3 complex 16 kDa subunit(gene name synonym) psi-mi:ascc3_human(display_long)|uniprotkb:ASCC3(gene name)|psi-mi:ASCC3(display_short)|uniprotkb:HELIC1(gene name synonym)|uniprotkb:ASC-1 complex subunit p200(gene name synonym)|uniprotkb:Trip4 complex subunit p200(gene name synonym)|uniprotkb:Helicase, ATP binding 1(gene name synonym)|uniprotkb:RQT2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476124|imex:IM-26985-383 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005708.1|refseq:NP_001257368.1|dip:DIP-33144N|ensembl:ENSG00000162704(gene)|ensembl:ENST00000359856(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0014909"(smooth muscle cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0021769"(orbitofrontal cortex development)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030426"(growth cone)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035861"(site of double-strand break)|go:"GO:0051639"(actin filament network formation)|go:"GO:0061842"(microtubule organizing center localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097581"(lamellipodium organization)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR006789("ARP2/3 complex 16 kDa subunit (p16-Arc)")|interpro:IPR036743|mint:O15511|rcsb pdb:6UHC|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-6798695|reactome:R-HSA-8856828|reactome:R-HSA-9664422 refseq:NP_001271200.1|refseq:NP_006819.2|refseq:NP_071374.1|ensembl:ENSG00000112249(gene)|ensembl:ENST00000369162(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006307"(DNA dealkylation involved in DNA repair)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0099053"(activating signal cointegrator 1 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004179(Sec63)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR027417|interpro:IPR035892|interpro:IPR036388|interpro:IPR036390|mint:Q8N3C0|rcsb pdb:6YXQ|reactome:R-HSA-112126|go:"GO:0005829"(cytosol) - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:kfZQK6CXdREnQNI1h+GlQpB/gPI9606 rogid:HAdhxBtWHxdw7k0GkyqBtloVyPY9606 rigid:RgDUqf8WE4yFHlNXOCnMn9qah4U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15511 uniprotkb:Q9P1U1 intact:EBI-352975|uniprotkb:A6NEC4|uniprotkb:Q6PG42|ensembl:ENSP00000352918 intact:EBI-1047175|uniprotkb:Q7Z526|uniprotkb:Q96BT2|uniprotkb:A8MTG1|uniprotkb:B4DFW4|ensembl:ENSP00000256001 psi-mi:arpc5_human(display_long)|uniprotkb:ARPC5(gene name)|psi-mi:ARPC5(display_short)|uniprotkb:ARC16(gene name synonym)|uniprotkb:Arp2/3 complex 16 kDa subunit(gene name synonym) psi-mi:arp3b_human(display_long)|uniprotkb:ARP4(gene name synonym)|uniprotkb:Actin-like protein 3B(gene name synonym)|uniprotkb:ARP3-beta(gene name synonym)|uniprotkb:Actin-related protein ARP4(gene name synonym)|uniprotkb:ACTR3B(gene name)|psi-mi:ACTR3B(display_short)|uniprotkb:ARP11(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476124|imex:IM-26985-383 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005708.1|refseq:NP_001257368.1|dip:DIP-33144N|ensembl:ENSG00000162704(gene)|ensembl:ENST00000359856(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0014909"(smooth muscle cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0021769"(orbitofrontal cortex development)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030426"(growth cone)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035861"(site of double-strand break)|go:"GO:0051639"(actin filament network formation)|go:"GO:0061842"(microtubule organizing center localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097581"(lamellipodium organization)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR006789("ARP2/3 complex 16 kDa subunit (p16-Arc)")|interpro:IPR036743|mint:O15511|rcsb pdb:6UHC|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-6798695|reactome:R-HSA-8856828|reactome:R-HSA-9664422 refseq:NP_001035225.1|refseq:NP_065178.1|ensembl:ENSG00000133627(gene)|ensembl:ENST00000256001(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0042995"(cell projection)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR043129|mint:Q9P1U1 - - comment:"author score: 33" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:kfZQK6CXdREnQNI1h+GlQpB/gPI9606 rogid:SKF1gLSYzo6jWlBcukVF0DBimA09606 rigid:RgDUqf8WE4yFHlNXOCnMn9qah4U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15511 uniprotkb:O15145 intact:EBI-352975|uniprotkb:A6NEC4|uniprotkb:Q6PG42|ensembl:ENSP00000352918 intact:EBI-351829|uniprotkb:O00554|ensembl:ENSP00000228825 psi-mi:arpc5_human(display_long)|uniprotkb:ARPC5(gene name)|psi-mi:ARPC5(display_short)|uniprotkb:ARC16(gene name synonym)|uniprotkb:Arp2/3 complex 16 kDa subunit(gene name synonym) psi-mi:arpc3_human(display_long)|uniprotkb:ARPC3(gene name)|psi-mi:ARPC3(display_short)|uniprotkb:ARC21(gene name synonym)|uniprotkb:Arp2/3 complex 21 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476124|imex:IM-26985-383 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005708.1|refseq:NP_001257368.1|dip:DIP-33144N|ensembl:ENSG00000162704(gene)|ensembl:ENST00000359856(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0014909"(smooth muscle cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0021769"(orbitofrontal cortex development)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030426"(growth cone)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035861"(site of double-strand break)|go:"GO:0051639"(actin filament network formation)|go:"GO:0061842"(microtubule organizing center localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097581"(lamellipodium organization)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR006789("ARP2/3 complex 16 kDa subunit (p16-Arc)")|interpro:IPR036743|mint:O15511|rcsb pdb:6UHC|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-6798695|reactome:R-HSA-8856828|reactome:R-HSA-9664422 ensembl:ENSG00000111229(gene)|ensembl:ENST00000228825(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0031941"(filamentous actin)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0061850"(growth cone leading edge)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR007204(ARP2/3 complex, 21 kDa p21-Arc subunit)|interpro:IPR036753|mint:O15145|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|refseq:NP_001274151.1|refseq:NP_001265485.1|dip:DIP-33187N - - comment:"author score: 171" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:kfZQK6CXdREnQNI1h+GlQpB/gPI9606 rogid:u4h1270mPo3E3GBrEurYtpUYTQM9606 rigid:RgDUqf8WE4yFHlNXOCnMn9qah4U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15511 uniprotkb:O15143 intact:EBI-352975|uniprotkb:A6NEC4|uniprotkb:Q6PG42|ensembl:ENSP00000352918 intact:EBI-1044647|uniprotkb:Q9BU00|ensembl:ENSP00000388802|ensembl:ENSP00000389631|ensembl:ENSP00000398110|ensembl:ENSP00000403211|ensembl:ENSP00000410238|ensembl:ENSP00000494033|ensembl:ENSP00000496599 psi-mi:arpc5_human(display_long)|uniprotkb:ARPC5(gene name)|psi-mi:ARPC5(display_short)|uniprotkb:ARC16(gene name synonym)|uniprotkb:Arp2/3 complex 16 kDa subunit(gene name synonym) psi-mi:arc1b_human(display_long)|uniprotkb:Arp2/3 complex 41 kDa subunit(gene name synonym)|uniprotkb:p41-ARC(gene name synonym)|uniprotkb:ARPC1B(gene name)|psi-mi:ARPC1B(display_short)|uniprotkb:ARC41(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476124|imex:IM-26985-383 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005708.1|refseq:NP_001257368.1|dip:DIP-33144N|ensembl:ENSG00000162704(gene)|ensembl:ENST00000359856(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0014909"(smooth muscle cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0021769"(orbitofrontal cortex development)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030426"(growth cone)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035861"(site of double-strand break)|go:"GO:0051639"(actin filament network formation)|go:"GO:0061842"(microtubule organizing center localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097581"(lamellipodium organization)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR006789("ARP2/3 complex 16 kDa subunit (p16-Arc)")|interpro:IPR036743|mint:O15511|rcsb pdb:6UHC|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-6798695|reactome:R-HSA-8856828|reactome:R-HSA-9664422 refseq:NP_005711.1|ensembl:ENSG00000130429(gene)|ensembl:ENST00000427217(transcript)|ensembl:ENST00000431816(transcript)|ensembl:ENST00000451682(transcript)|ensembl:ENST00000455009(transcript)|ensembl:ENST00000458033(transcript)|ensembl:ENST00000645391(transcript)|ensembl:ENST00000646101(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032355"(response to estradiol)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0036284"(tubulobulbar complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR030141|interpro:IPR036322|mint:O15143|rcsb pdb:6UHC|rcsb pdb:6YW6|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-9664422|refseq:XP_006715888.1|refseq:XP_006715889.1|dip:DIP-41254N - - comment:"author score: 221" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:kfZQK6CXdREnQNI1h+GlQpB/gPI9606 rogid:sx7R5hirSnqoXyOlW6ltrpNjUIs9606 rigid:RgDUqf8WE4yFHlNXOCnMn9qah4U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15511 uniprotkb:O15144 intact:EBI-352975|uniprotkb:A6NEC4|uniprotkb:Q6PG42|ensembl:ENSP00000352918 intact:EBI-352356|uniprotkb:Q92801|uniprotkb:Q9P1D4|ensembl:ENSP00000295685|ensembl:ENSP00000327137 psi-mi:arpc5_human(display_long)|uniprotkb:ARPC5(gene name)|psi-mi:ARPC5(display_short)|uniprotkb:ARC16(gene name synonym)|uniprotkb:Arp2/3 complex 16 kDa subunit(gene name synonym) psi-mi:arpc2_human(display_long)|uniprotkb:ARPC2(gene name)|psi-mi:ARPC2(display_short)|uniprotkb:ARC34(gene name synonym)|uniprotkb:PRO2446(orf name)|uniprotkb:Arp2/3 complex 34 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476124|imex:IM-26985-383 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005708.1|refseq:NP_001257368.1|dip:DIP-33144N|ensembl:ENSG00000162704(gene)|ensembl:ENST00000359856(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0014909"(smooth muscle cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0021769"(orbitofrontal cortex development)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030426"(growth cone)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035861"(site of double-strand break)|go:"GO:0051639"(actin filament network formation)|go:"GO:0061842"(microtubule organizing center localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097581"(lamellipodium organization)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR006789("ARP2/3 complex 16 kDa subunit (p16-Arc)")|interpro:IPR036743|mint:O15511|rcsb pdb:6UHC|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-6798695|reactome:R-HSA-8856828|reactome:R-HSA-9664422 refseq:NP_005722.1|refseq:NP_690601.1|go:"GO:0005925"(focal adhesion)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036195"(muscle cell projection membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|interpro:IPR007188(Arp2/3 complex, 34kDa subunit p34-Arc)|interpro:IPR034666|mint:O15144|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|go:"GO:0005885"(Arp2/3 protein complex)|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|reactome:R-HSA-3928662|ensembl:ENSG00000163466(gene)|ensembl:ENST00000295685(transcript)|ensembl:ENST00000315717(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|dip:DIP-33197N - - comment:"author score: 316" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:kfZQK6CXdREnQNI1h+GlQpB/gPI9606 rogid:v5OozQTt614rvrBBoUavbAzjgZ49606 rigid:RgDUqf8WE4yFHlNXOCnMn9qah4U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15511 uniprotkb:P61158 intact:EBI-352975|uniprotkb:A6NEC4|uniprotkb:Q6PG42|ensembl:ENSP00000352918 intact:EBI-351428|uniprotkb:P32391|ensembl:ENSP00000263238|uniprotkb:Q53QM2 psi-mi:arpc5_human(display_long)|uniprotkb:ARPC5(gene name)|psi-mi:ARPC5(display_short)|uniprotkb:ARC16(gene name synonym)|uniprotkb:Arp2/3 complex 16 kDa subunit(gene name synonym) psi-mi:arp3_human(display_long)|uniprotkb:ACTR3(gene name)|psi-mi:ACTR3(display_short)|uniprotkb:ARP3(gene name synonym)|uniprotkb:Actin-like protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476124|imex:IM-26985-383 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005708.1|refseq:NP_001257368.1|dip:DIP-33144N|ensembl:ENSG00000162704(gene)|ensembl:ENST00000359856(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0014909"(smooth muscle cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0021769"(orbitofrontal cortex development)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030426"(growth cone)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035861"(site of double-strand break)|go:"GO:0051639"(actin filament network formation)|go:"GO:0061842"(microtubule organizing center localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097581"(lamellipodium organization)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR006789("ARP2/3 complex 16 kDa subunit (p16-Arc)")|interpro:IPR036743|mint:O15511|rcsb pdb:6UHC|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-6798695|reactome:R-HSA-8856828|reactome:R-HSA-9664422 refseq:NP_005712.1|ensembl:ENSG00000115091(gene)|ensembl:ENST00000263238(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016344"(meiotic chromosome movement towards spindle pole)|go:"GO:0030027"(lamellipodium)|go:"GO:0033206"(meiotic cytokinesis)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051653"(spindle localization)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR004000(Actin/actin-like)|interpro:IPR015623(Actin-related protein 3)|interpro:IPR020902|interpro:IPR043129|mint:P61158|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|dip:DIP-33140N - - comment:"author score: 353" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:kfZQK6CXdREnQNI1h+GlQpB/gPI9606 rogid:XbkZeKzG8lGbT8dxYkGqeJT0vEg9606 rigid:RgDUqf8WE4yFHlNXOCnMn9qah4U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15511 uniprotkb:P61160 intact:EBI-352975|uniprotkb:A6NEC4|uniprotkb:Q6PG42|ensembl:ENSP00000352918 intact:EBI-353580|ensembl:ENSP00000260641|uniprotkb:O15142|uniprotkb:Q96C82|uniprotkb:B2RCP5|uniprotkb:D6W5F4|uniprotkb:E9PF41 psi-mi:arpc5_human(display_long)|uniprotkb:ARPC5(gene name)|psi-mi:ARPC5(display_short)|uniprotkb:ARC16(gene name synonym)|uniprotkb:Arp2/3 complex 16 kDa subunit(gene name synonym) psi-mi:arp2_human(display_long)|uniprotkb:ACTR2(gene name)|psi-mi:ACTR2(display_short)|uniprotkb:ARP2(gene name synonym)|uniprotkb:Actin-like protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476124|imex:IM-26985-383 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005708.1|refseq:NP_001257368.1|dip:DIP-33144N|ensembl:ENSG00000162704(gene)|ensembl:ENST00000359856(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0014909"(smooth muscle cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0021769"(orbitofrontal cortex development)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030426"(growth cone)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035861"(site of double-strand break)|go:"GO:0051639"(actin filament network formation)|go:"GO:0061842"(microtubule organizing center localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097581"(lamellipodium organization)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR006789("ARP2/3 complex 16 kDa subunit (p16-Arc)")|interpro:IPR036743|mint:O15511|rcsb pdb:6UHC|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-6798695|reactome:R-HSA-8856828|reactome:R-HSA-9664422 ensembl:ENSG00000138071(gene)|ensembl:ENST00000260641(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008306"(associative learning)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016344"(meiotic chromosome movement towards spindle pole)|go:"GO:0016482"(cytosolic transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0030478"(actin cap)|go:"GO:0033206"(meiotic cytokinesis)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035861"(site of double-strand break)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0045471"(response to ethanol)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051653"(spindle localization)|go:"GO:0060271"(cilium assembly)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061825"(podosome core)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1904813"(ficolin-1-rich granule lumen)|refseq:NP_001005386.1|refseq:NP_005713.1|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR043129|mint:P61160|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-6798695|reactome:R-HSA-8856828|reactome:R-HSA-9664422|dip:DIP-33165N - - comment:"author score: 381" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:kfZQK6CXdREnQNI1h+GlQpB/gPI9606 rogid:URQsZpIsMtsFZAnpLYDDvgKcPqA9606 rigid:RgDUqf8WE4yFHlNXOCnMn9qah4U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92747 uniprotkb:P09455 intact:EBI-1020827|uniprotkb:Q7Z5U8|uniprotkb:Q86WU5|uniprotkb:Q8IXQ0|uniprotkb:A4D276|uniprotkb:D6W5S1|ensembl:ENSP00000262942|uniprotkb:B4DLQ7 intact:EBI-2623483|ensembl:ENSP00000482165|intact:EBI-3933584|uniprotkb:B7Z7A0|uniprotkb:E7EWV0|uniprotkb:F2Z2F2|uniprotkb:Q6FGX8|uniprotkb:A8K2Q0 psi-mi:arc1a_human(display_long)|uniprotkb:ARPC1A(gene name)|psi-mi:ARPC1A(display_short)|uniprotkb:SOP2L(gene name synonym)|uniprotkb:SOP2-like protein(gene name synonym) psi-mi:ret1_human(display_long)|uniprotkb:RBP1(gene name)|psi-mi:RBP1(display_short)|uniprotkb:CRBP1(gene name synonym)|uniprotkb:Cellular retinol-binding protein(gene name synonym)|uniprotkb:Cellular retinol-binding protein I(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476058|imex:IM-26985-227 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006400.2|ensembl:ENSG00000241685(gene)|ensembl:ENST00000262942(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR030140|interpro:IPR036322|mint:Q92747|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|dip:DIP-33142N refseq:NP_001124465.1|ensembl:ENSG00000114115(gene)|ensembl:ENST00000619087(transcript)|go:"GO:0002138"(retinoic acid biosynthetic process)|go:"GO:0005501"(retinoid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006776"(vitamin A metabolic process)|go:"GO:0016918"(retinal binding)|go:"GO:0055088"(lipid homeostasis)|go:"GO:1904768"(all-trans-retinol binding)|interpro:IPR000463(Cytosolic fatty-acid binding)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR012674(Calycin)|interpro:IPR031259|interpro:IPR031264|mint:P09455|rcsb pdb:5H8T|rcsb pdb:5H9A|rcsb pdb:5HA1|rcsb pdb:5HBS|rcsb pdb:5LJB|rcsb pdb:5LJC|rcsb pdb:5LJD|rcsb pdb:5LJE|rcsb pdb:5LJG|rcsb pdb:5LJH|rcsb pdb:5LJK|rcsb pdb:6E5L|rcsb pdb:6E5T|rcsb pdb:6E6M|reactome:R-HSA-2453864|reactome:R-HSA-2453902|reactome:R-HSA-975634|refseq:NP_002890.2|refseq:NP_001124464.1 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ACqXC+XYl9R9Z7mHhpw7vt1SPu49606 rogid:QxKuGge3qk7Q9lmPxlKV112cdBc9606 rigid:LcxBc2JpPOrBxMHaNeiFtiWWa2I false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92747 uniprotkb:Q9BPX5 intact:EBI-1020827|uniprotkb:Q7Z5U8|uniprotkb:Q86WU5|uniprotkb:Q8IXQ0|uniprotkb:A4D276|uniprotkb:D6W5S1|ensembl:ENSP00000262942|uniprotkb:B4DLQ7 intact:EBI-711189|ensembl:ENSP00000259477|ensembl:ENSP00000345361|uniprotkb:Q7Z523 psi-mi:arc1a_human(display_long)|uniprotkb:ARPC1A(gene name)|psi-mi:ARPC1A(display_short)|uniprotkb:SOP2L(gene name synonym)|uniprotkb:SOP2-like protein(gene name synonym) psi-mi:arp5l_human(display_long)|uniprotkb:Arp2/3 complex 16 kDa subunit 2(gene name synonym)|uniprotkb:ARPC5L(gene name)|psi-mi:ARPC5L(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476058|imex:IM-26985-227 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006400.2|ensembl:ENSG00000241685(gene)|ensembl:ENST00000262942(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR030140|interpro:IPR036322|mint:Q92747|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|dip:DIP-33142N refseq:NP_112240.1|ensembl:ENSG00000136950(gene)|ensembl:ENST00000259477(transcript)|ensembl:ENST00000353214(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0016477"(cell migration)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR006789("ARP2/3 complex 16 kDa subunit (p16-Arc)")|interpro:IPR030075|interpro:IPR036743|mint:Q9BPX5|rcsb pdb:6YW6|dip:DIP-50399N - - comment:"author score: 157" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ACqXC+XYl9R9Z7mHhpw7vt1SPu49606 rogid:JVproBu8rIrnlk39yXPC+ZrvoOk9606 rigid:LcxBc2JpPOrBxMHaNeiFtiWWa2I false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92747 uniprotkb:O15145 intact:EBI-1020827|uniprotkb:Q7Z5U8|uniprotkb:Q86WU5|uniprotkb:Q8IXQ0|uniprotkb:A4D276|uniprotkb:D6W5S1|ensembl:ENSP00000262942|uniprotkb:B4DLQ7 intact:EBI-351829|uniprotkb:O00554|ensembl:ENSP00000228825 psi-mi:arc1a_human(display_long)|uniprotkb:ARPC1A(gene name)|psi-mi:ARPC1A(display_short)|uniprotkb:SOP2L(gene name synonym)|uniprotkb:SOP2-like protein(gene name synonym) psi-mi:arpc3_human(display_long)|uniprotkb:ARPC3(gene name)|psi-mi:ARPC3(display_short)|uniprotkb:ARC21(gene name synonym)|uniprotkb:Arp2/3 complex 21 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476058|imex:IM-26985-227 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006400.2|ensembl:ENSG00000241685(gene)|ensembl:ENST00000262942(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR030140|interpro:IPR036322|mint:Q92747|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|dip:DIP-33142N ensembl:ENSG00000111229(gene)|ensembl:ENST00000228825(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0031941"(filamentous actin)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0061850"(growth cone leading edge)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR007204(ARP2/3 complex, 21 kDa p21-Arc subunit)|interpro:IPR036753|mint:O15145|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|refseq:NP_001274151.1|refseq:NP_001265485.1|dip:DIP-33187N - - comment:"author score: 175" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ACqXC+XYl9R9Z7mHhpw7vt1SPu49606 rogid:u4h1270mPo3E3GBrEurYtpUYTQM9606 rigid:LcxBc2JpPOrBxMHaNeiFtiWWa2I false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92747 uniprotkb:P61158 intact:EBI-1020827|uniprotkb:Q7Z5U8|uniprotkb:Q86WU5|uniprotkb:Q8IXQ0|uniprotkb:A4D276|uniprotkb:D6W5S1|ensembl:ENSP00000262942|uniprotkb:B4DLQ7 intact:EBI-351428|uniprotkb:P32391|ensembl:ENSP00000263238|uniprotkb:Q53QM2 psi-mi:arc1a_human(display_long)|uniprotkb:ARPC1A(gene name)|psi-mi:ARPC1A(display_short)|uniprotkb:SOP2L(gene name synonym)|uniprotkb:SOP2-like protein(gene name synonym) psi-mi:arp3_human(display_long)|uniprotkb:ACTR3(gene name)|psi-mi:ACTR3(display_short)|uniprotkb:ARP3(gene name synonym)|uniprotkb:Actin-like protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476058|imex:IM-26985-227 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006400.2|ensembl:ENSG00000241685(gene)|ensembl:ENST00000262942(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR030140|interpro:IPR036322|mint:Q92747|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|dip:DIP-33142N refseq:NP_005712.1|ensembl:ENSG00000115091(gene)|ensembl:ENST00000263238(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016344"(meiotic chromosome movement towards spindle pole)|go:"GO:0030027"(lamellipodium)|go:"GO:0033206"(meiotic cytokinesis)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051653"(spindle localization)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR004000(Actin/actin-like)|interpro:IPR015623(Actin-related protein 3)|interpro:IPR020902|interpro:IPR043129|mint:P61158|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|dip:DIP-33140N - - comment:"author score: 338" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ACqXC+XYl9R9Z7mHhpw7vt1SPu49606 rogid:XbkZeKzG8lGbT8dxYkGqeJT0vEg9606 rigid:LcxBc2JpPOrBxMHaNeiFtiWWa2I false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92747 uniprotkb:O15144 intact:EBI-1020827|uniprotkb:Q7Z5U8|uniprotkb:Q86WU5|uniprotkb:Q8IXQ0|uniprotkb:A4D276|uniprotkb:D6W5S1|ensembl:ENSP00000262942|uniprotkb:B4DLQ7 intact:EBI-352356|uniprotkb:Q92801|uniprotkb:Q9P1D4|ensembl:ENSP00000295685|ensembl:ENSP00000327137 psi-mi:arc1a_human(display_long)|uniprotkb:ARPC1A(gene name)|psi-mi:ARPC1A(display_short)|uniprotkb:SOP2L(gene name synonym)|uniprotkb:SOP2-like protein(gene name synonym) psi-mi:arpc2_human(display_long)|uniprotkb:ARPC2(gene name)|psi-mi:ARPC2(display_short)|uniprotkb:ARC34(gene name synonym)|uniprotkb:PRO2446(orf name)|uniprotkb:Arp2/3 complex 34 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476058|imex:IM-26985-227 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006400.2|ensembl:ENSG00000241685(gene)|ensembl:ENST00000262942(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR030140|interpro:IPR036322|mint:Q92747|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|dip:DIP-33142N refseq:NP_005722.1|refseq:NP_690601.1|go:"GO:0005925"(focal adhesion)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036195"(muscle cell projection membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|interpro:IPR007188(Arp2/3 complex, 34kDa subunit p34-Arc)|interpro:IPR034666|mint:O15144|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|go:"GO:0005885"(Arp2/3 protein complex)|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|reactome:R-HSA-3928662|ensembl:ENSG00000163466(gene)|ensembl:ENST00000295685(transcript)|ensembl:ENST00000315717(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|dip:DIP-33197N - - comment:"author score: 349" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ACqXC+XYl9R9Z7mHhpw7vt1SPu49606 rogid:v5OozQTt614rvrBBoUavbAzjgZ49606 rigid:LcxBc2JpPOrBxMHaNeiFtiWWa2I false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92747 uniprotkb:P61160 intact:EBI-1020827|uniprotkb:Q7Z5U8|uniprotkb:Q86WU5|uniprotkb:Q8IXQ0|uniprotkb:A4D276|uniprotkb:D6W5S1|ensembl:ENSP00000262942|uniprotkb:B4DLQ7 intact:EBI-353580|ensembl:ENSP00000260641|uniprotkb:O15142|uniprotkb:Q96C82|uniprotkb:B2RCP5|uniprotkb:D6W5F4|uniprotkb:E9PF41 psi-mi:arc1a_human(display_long)|uniprotkb:ARPC1A(gene name)|psi-mi:ARPC1A(display_short)|uniprotkb:SOP2L(gene name synonym)|uniprotkb:SOP2-like protein(gene name synonym) psi-mi:arp2_human(display_long)|uniprotkb:ACTR2(gene name)|psi-mi:ACTR2(display_short)|uniprotkb:ARP2(gene name synonym)|uniprotkb:Actin-like protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476058|imex:IM-26985-227 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006400.2|ensembl:ENSG00000241685(gene)|ensembl:ENST00000262942(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR030140|interpro:IPR036322|mint:Q92747|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|dip:DIP-33142N ensembl:ENSG00000138071(gene)|ensembl:ENST00000260641(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008306"(associative learning)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016344"(meiotic chromosome movement towards spindle pole)|go:"GO:0016482"(cytosolic transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0030478"(actin cap)|go:"GO:0033206"(meiotic cytokinesis)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035861"(site of double-strand break)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0045471"(response to ethanol)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051653"(spindle localization)|go:"GO:0060271"(cilium assembly)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061825"(podosome core)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1904813"(ficolin-1-rich granule lumen)|refseq:NP_001005386.1|refseq:NP_005713.1|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR043129|mint:P61160|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-6798695|reactome:R-HSA-8856828|reactome:R-HSA-9664422|dip:DIP-33165N - - comment:"author score: 376" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ACqXC+XYl9R9Z7mHhpw7vt1SPu49606 rogid:URQsZpIsMtsFZAnpLYDDvgKcPqA9606 rigid:LcxBc2JpPOrBxMHaNeiFtiWWa2I false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92747 uniprotkb:O15511 intact:EBI-1020827|uniprotkb:Q7Z5U8|uniprotkb:Q86WU5|uniprotkb:Q8IXQ0|uniprotkb:A4D276|uniprotkb:D6W5S1|ensembl:ENSP00000262942|uniprotkb:B4DLQ7 intact:EBI-352975|uniprotkb:A6NEC4|uniprotkb:Q6PG42|ensembl:ENSP00000352918 psi-mi:arc1a_human(display_long)|uniprotkb:ARPC1A(gene name)|psi-mi:ARPC1A(display_short)|uniprotkb:SOP2L(gene name synonym)|uniprotkb:SOP2-like protein(gene name synonym) psi-mi:arpc5_human(display_long)|uniprotkb:ARPC5(gene name)|psi-mi:ARPC5(display_short)|uniprotkb:ARC16(gene name synonym)|uniprotkb:Arp2/3 complex 16 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476058|imex:IM-26985-227 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006400.2|ensembl:ENSG00000241685(gene)|ensembl:ENST00000262942(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR030140|interpro:IPR036322|mint:Q92747|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|dip:DIP-33142N refseq:NP_005708.1|refseq:NP_001257368.1|dip:DIP-33144N|ensembl:ENSG00000162704(gene)|ensembl:ENST00000359856(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0014909"(smooth muscle cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0021769"(orbitofrontal cortex development)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030426"(growth cone)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035861"(site of double-strand break)|go:"GO:0051639"(actin filament network formation)|go:"GO:0061842"(microtubule organizing center localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097581"(lamellipodium organization)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR006789("ARP2/3 complex 16 kDa subunit (p16-Arc)")|interpro:IPR036743|mint:O15511|rcsb pdb:6UHC|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-6798695|reactome:R-HSA-8856828|reactome:R-HSA-9664422 - - comment:"author score: 400" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ACqXC+XYl9R9Z7mHhpw7vt1SPu49606 rogid:kfZQK6CXdREnQNI1h+GlQpB/gPI9606 rigid:LcxBc2JpPOrBxMHaNeiFtiWWa2I false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59998 uniprotkb:Q13748 intact:EBI-351872|uniprotkb:O15509|uniprotkb:C9JWM7|uniprotkb:E7ETI0|uniprotkb:Q6P0W5|uniprotkb:Q96QJ3|ensembl:ENSP00000380431|uniprotkb:F6TTL5 intact:EBI-355068|uniprotkb:A6NJQ0|uniprotkb:Q5W099|uniprotkb:Q6PEY3|uniprotkb:Q96F18|uniprotkb:P0DPH8|uniprotkb:P0DPH7 psi-mi:arpc4_human(display_long)|uniprotkb:ARPC4(gene name)|psi-mi:ARPC4(display_short)|uniprotkb:ARC20(gene name synonym)|uniprotkb:Arp2/3 complex 20 kDa subunit(gene name synonym) psi-mi:tba3c_human(display_long)|uniprotkb:TUBA3C(gene name)|psi-mi:TUBA3C(display_short)|uniprotkb:TUBA3D(gene name)|psi-mi:TUBA3D(display_short)|uniprotkb:TUBA2(gene name synonym)|uniprotkb:Alpha-tubulin 3C/D(gene name synonym)|uniprotkb:Tubulin alpha-2 chain(gene name synonym)|uniprotkb:Alpha-tubulin 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476085|imex:IM-26985-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001185709.1|refseq:NP_005709.1|ensembl:ENSG00000241553(gene)|ensembl:ENST00000397261(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042995"(cell projection)|go:"GO:0045010"(actin nucleation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008384(ARP23 complex 20 kDa subunit)|interpro:IPR034666|mint:P59998|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|refseq:NP_001020130.1|refseq:NP_001020131.1|dip:DIP-33188N go:"GO:0005200"(structural constituent of cytoskeleton)|ensembl:ENSG00000075886|ensembl:ENSG00000198033|ensembl:ENSP00000326042|ensembl:ENSP00000382982|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005525"(GTP binding)|go:"GO:0003924"(GTPase activity)|refseq:NP_005992.1|refseq:NP_525125.2|interpro:IPR002452(Alpha tubulin)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR000217(Tubulin)|interpro:IPR018316|interpro:IPR017975|interpro:IPR003008(Tubulin/FtsZ, GTPase)|ensembl:ENSP00000482878|ensembl:ENST00000618094|reactome:R-HSA-6807878|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-983189|go:"GO:0007017"(microtubule-based process)|go:"GO:0005634"(nucleus)|ensembl:ENST00000321253|ensembl:ENST00000400113|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-8852276|go:"GO:0015630"(microtubule cytoskeleton)|interpro:IPR023123|mint:Q13748|dip:DIP-34513N|reactome:R-HSA-3371497|reactome:R-HSA-8955332|interpro:IPR036525|interpro:IPR037103|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|go:"GO:0036064"(ciliary basal body) - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Iqe60TWfO3QBVOY+fOqZd9JWfIE9606 rogid:mE1Hcdc9AAMMxfxzKB6TfM6RrHE9606 rigid:A0zziuOH7bJ5Etu4YPD9X4jVTBc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59998 uniprotkb:Q9P1U1 intact:EBI-351872|uniprotkb:O15509|uniprotkb:C9JWM7|uniprotkb:E7ETI0|uniprotkb:Q6P0W5|uniprotkb:Q96QJ3|ensembl:ENSP00000380431|uniprotkb:F6TTL5 intact:EBI-1047175|uniprotkb:Q7Z526|uniprotkb:Q96BT2|uniprotkb:A8MTG1|uniprotkb:B4DFW4|ensembl:ENSP00000256001 psi-mi:arpc4_human(display_long)|uniprotkb:ARPC4(gene name)|psi-mi:ARPC4(display_short)|uniprotkb:ARC20(gene name synonym)|uniprotkb:Arp2/3 complex 20 kDa subunit(gene name synonym) psi-mi:arp3b_human(display_long)|uniprotkb:ARP4(gene name synonym)|uniprotkb:Actin-like protein 3B(gene name synonym)|uniprotkb:ARP3-beta(gene name synonym)|uniprotkb:Actin-related protein ARP4(gene name synonym)|uniprotkb:ACTR3B(gene name)|psi-mi:ACTR3B(display_short)|uniprotkb:ARP11(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476085|imex:IM-26985-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001185709.1|refseq:NP_005709.1|ensembl:ENSG00000241553(gene)|ensembl:ENST00000397261(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042995"(cell projection)|go:"GO:0045010"(actin nucleation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008384(ARP23 complex 20 kDa subunit)|interpro:IPR034666|mint:P59998|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|refseq:NP_001020130.1|refseq:NP_001020131.1|dip:DIP-33188N refseq:NP_001035225.1|refseq:NP_065178.1|ensembl:ENSG00000133627(gene)|ensembl:ENST00000256001(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0042995"(cell projection)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR043129|mint:Q9P1U1 - - comment:"author score: 53" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Iqe60TWfO3QBVOY+fOqZd9JWfIE9606 rogid:SKF1gLSYzo6jWlBcukVF0DBimA09606 rigid:A0zziuOH7bJ5Etu4YPD9X4jVTBc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59998 uniprotkb:Q8WUH1 intact:EBI-351872|uniprotkb:O15509|uniprotkb:C9JWM7|uniprotkb:E7ETI0|uniprotkb:Q6P0W5|uniprotkb:Q96QJ3|ensembl:ENSP00000380431|uniprotkb:F6TTL5 intact:EBI-11156883|ensembl:ENSP00000448050|ensembl:ENSP00000450165|ensembl:ENSP00000475473|uniprotkb:G3V214|uniprotkb:G3V1X3|uniprotkb:Q9H3K7|uniprotkb:B3KQ81 psi-mi:arpc4_human(display_long)|uniprotkb:ARPC4(gene name)|psi-mi:ARPC4(display_short)|uniprotkb:ARC20(gene name synonym)|uniprotkb:Arp2/3 complex 20 kDa subunit(gene name synonym) psi-mi:chur_human(display_long)|uniprotkb:CHURC1(gene name)|psi-mi:CHURC1(display_short)|uniprotkb:C14orf52(gene name synonym)|uniprotkb:CHCH(gene name synonym)|uniprotkb:My015(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476085|imex:IM-26985-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001185709.1|refseq:NP_005709.1|ensembl:ENSG00000241553(gene)|ensembl:ENST00000397261(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042995"(cell projection)|go:"GO:0045010"(actin nucleation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008384(ARP23 complex 20 kDa subunit)|interpro:IPR034666|mint:P59998|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|refseq:NP_001020130.1|refseq:NP_001020131.1|dip:DIP-33188N refseq:NP_001190992.1|refseq:NP_001190993.1|refseq:NP_660148.3|ensembl:ENSG00000258289(gene)|ensembl:ENST00000548752(transcript)|ensembl:ENST00000549115(transcript)|ensembl:ENST00000607599(transcript)|go:"GO:0008270"(zinc ion binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR009508(Churchill)|interpro:IPR038543|mint:Q8WUH1|rcsb pdb:2JOX - - comment:"author score: 65" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Iqe60TWfO3QBVOY+fOqZd9JWfIE9606 rogid:WKqPPbQGe0cMce6ZEUDae229/jU9606 rigid:A0zziuOH7bJ5Etu4YPD9X4jVTBc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59998 uniprotkb:O15145 intact:EBI-351872|uniprotkb:O15509|uniprotkb:C9JWM7|uniprotkb:E7ETI0|uniprotkb:Q6P0W5|uniprotkb:Q96QJ3|ensembl:ENSP00000380431|uniprotkb:F6TTL5 intact:EBI-351829|uniprotkb:O00554|ensembl:ENSP00000228825 psi-mi:arpc4_human(display_long)|uniprotkb:ARPC4(gene name)|psi-mi:ARPC4(display_short)|uniprotkb:ARC20(gene name synonym)|uniprotkb:Arp2/3 complex 20 kDa subunit(gene name synonym) psi-mi:arpc3_human(display_long)|uniprotkb:ARPC3(gene name)|psi-mi:ARPC3(display_short)|uniprotkb:ARC21(gene name synonym)|uniprotkb:Arp2/3 complex 21 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476085|imex:IM-26985-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001185709.1|refseq:NP_005709.1|ensembl:ENSG00000241553(gene)|ensembl:ENST00000397261(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042995"(cell projection)|go:"GO:0045010"(actin nucleation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008384(ARP23 complex 20 kDa subunit)|interpro:IPR034666|mint:P59998|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|refseq:NP_001020130.1|refseq:NP_001020131.1|dip:DIP-33188N ensembl:ENSG00000111229(gene)|ensembl:ENST00000228825(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0031941"(filamentous actin)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0061850"(growth cone leading edge)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR007204(ARP2/3 complex, 21 kDa p21-Arc subunit)|interpro:IPR036753|mint:O15145|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|refseq:NP_001274151.1|refseq:NP_001265485.1|dip:DIP-33187N - - comment:"author score: 205" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Iqe60TWfO3QBVOY+fOqZd9JWfIE9606 rogid:u4h1270mPo3E3GBrEurYtpUYTQM9606 rigid:A0zziuOH7bJ5Etu4YPD9X4jVTBc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59998 uniprotkb:Q9BPX5 intact:EBI-351872|uniprotkb:O15509|uniprotkb:C9JWM7|uniprotkb:E7ETI0|uniprotkb:Q6P0W5|uniprotkb:Q96QJ3|ensembl:ENSP00000380431|uniprotkb:F6TTL5 intact:EBI-711189|ensembl:ENSP00000259477|ensembl:ENSP00000345361|uniprotkb:Q7Z523 psi-mi:arpc4_human(display_long)|uniprotkb:ARPC4(gene name)|psi-mi:ARPC4(display_short)|uniprotkb:ARC20(gene name synonym)|uniprotkb:Arp2/3 complex 20 kDa subunit(gene name synonym) psi-mi:arp5l_human(display_long)|uniprotkb:Arp2/3 complex 16 kDa subunit 2(gene name synonym)|uniprotkb:ARPC5L(gene name)|psi-mi:ARPC5L(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476085|imex:IM-26985-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001185709.1|refseq:NP_005709.1|ensembl:ENSG00000241553(gene)|ensembl:ENST00000397261(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042995"(cell projection)|go:"GO:0045010"(actin nucleation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008384(ARP23 complex 20 kDa subunit)|interpro:IPR034666|mint:P59998|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|refseq:NP_001020130.1|refseq:NP_001020131.1|dip:DIP-33188N refseq:NP_112240.1|ensembl:ENSG00000136950(gene)|ensembl:ENST00000259477(transcript)|ensembl:ENST00000353214(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0016477"(cell migration)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR006789("ARP2/3 complex 16 kDa subunit (p16-Arc)")|interpro:IPR030075|interpro:IPR036743|mint:Q9BPX5|rcsb pdb:6YW6|dip:DIP-50399N - - comment:"author score: 208" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Iqe60TWfO3QBVOY+fOqZd9JWfIE9606 rogid:JVproBu8rIrnlk39yXPC+ZrvoOk9606 rigid:A0zziuOH7bJ5Etu4YPD9X4jVTBc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59998 uniprotkb:O15143 intact:EBI-351872|uniprotkb:O15509|uniprotkb:C9JWM7|uniprotkb:E7ETI0|uniprotkb:Q6P0W5|uniprotkb:Q96QJ3|ensembl:ENSP00000380431|uniprotkb:F6TTL5 intact:EBI-1044647|uniprotkb:Q9BU00|ensembl:ENSP00000388802|ensembl:ENSP00000389631|ensembl:ENSP00000398110|ensembl:ENSP00000403211|ensembl:ENSP00000410238|ensembl:ENSP00000494033|ensembl:ENSP00000496599 psi-mi:arpc4_human(display_long)|uniprotkb:ARPC4(gene name)|psi-mi:ARPC4(display_short)|uniprotkb:ARC20(gene name synonym)|uniprotkb:Arp2/3 complex 20 kDa subunit(gene name synonym) psi-mi:arc1b_human(display_long)|uniprotkb:Arp2/3 complex 41 kDa subunit(gene name synonym)|uniprotkb:p41-ARC(gene name synonym)|uniprotkb:ARPC1B(gene name)|psi-mi:ARPC1B(display_short)|uniprotkb:ARC41(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476085|imex:IM-26985-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001185709.1|refseq:NP_005709.1|ensembl:ENSG00000241553(gene)|ensembl:ENST00000397261(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042995"(cell projection)|go:"GO:0045010"(actin nucleation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008384(ARP23 complex 20 kDa subunit)|interpro:IPR034666|mint:P59998|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|refseq:NP_001020130.1|refseq:NP_001020131.1|dip:DIP-33188N refseq:NP_005711.1|ensembl:ENSG00000130429(gene)|ensembl:ENST00000427217(transcript)|ensembl:ENST00000431816(transcript)|ensembl:ENST00000451682(transcript)|ensembl:ENST00000455009(transcript)|ensembl:ENST00000458033(transcript)|ensembl:ENST00000645391(transcript)|ensembl:ENST00000646101(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032355"(response to estradiol)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0036284"(tubulobulbar complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR030141|interpro:IPR036322|mint:O15143|rcsb pdb:6UHC|rcsb pdb:6YW6|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-9664422|refseq:XP_006715888.1|refseq:XP_006715889.1|dip:DIP-41254N - - comment:"author score: 288" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Iqe60TWfO3QBVOY+fOqZd9JWfIE9606 rogid:sx7R5hirSnqoXyOlW6ltrpNjUIs9606 rigid:A0zziuOH7bJ5Etu4YPD9X4jVTBc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59998 uniprotkb:P61158 intact:EBI-351872|uniprotkb:O15509|uniprotkb:C9JWM7|uniprotkb:E7ETI0|uniprotkb:Q6P0W5|uniprotkb:Q96QJ3|ensembl:ENSP00000380431|uniprotkb:F6TTL5 intact:EBI-351428|uniprotkb:P32391|ensembl:ENSP00000263238|uniprotkb:Q53QM2 psi-mi:arpc4_human(display_long)|uniprotkb:ARPC4(gene name)|psi-mi:ARPC4(display_short)|uniprotkb:ARC20(gene name synonym)|uniprotkb:Arp2/3 complex 20 kDa subunit(gene name synonym) psi-mi:arp3_human(display_long)|uniprotkb:ACTR3(gene name)|psi-mi:ACTR3(display_short)|uniprotkb:ARP3(gene name synonym)|uniprotkb:Actin-like protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476085|imex:IM-26985-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001185709.1|refseq:NP_005709.1|ensembl:ENSG00000241553(gene)|ensembl:ENST00000397261(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042995"(cell projection)|go:"GO:0045010"(actin nucleation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008384(ARP23 complex 20 kDa subunit)|interpro:IPR034666|mint:P59998|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|refseq:NP_001020130.1|refseq:NP_001020131.1|dip:DIP-33188N refseq:NP_005712.1|ensembl:ENSG00000115091(gene)|ensembl:ENST00000263238(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016344"(meiotic chromosome movement towards spindle pole)|go:"GO:0030027"(lamellipodium)|go:"GO:0033206"(meiotic cytokinesis)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051653"(spindle localization)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR004000(Actin/actin-like)|interpro:IPR015623(Actin-related protein 3)|interpro:IPR020902|interpro:IPR043129|mint:P61158|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|dip:DIP-33140N - - comment:"author score: 383" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Iqe60TWfO3QBVOY+fOqZd9JWfIE9606 rogid:XbkZeKzG8lGbT8dxYkGqeJT0vEg9606 rigid:A0zziuOH7bJ5Etu4YPD9X4jVTBc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59998 uniprotkb:O15511 intact:EBI-351872|uniprotkb:O15509|uniprotkb:C9JWM7|uniprotkb:E7ETI0|uniprotkb:Q6P0W5|uniprotkb:Q96QJ3|ensembl:ENSP00000380431|uniprotkb:F6TTL5 intact:EBI-352975|uniprotkb:A6NEC4|uniprotkb:Q6PG42|ensembl:ENSP00000352918 psi-mi:arpc4_human(display_long)|uniprotkb:ARPC4(gene name)|psi-mi:ARPC4(display_short)|uniprotkb:ARC20(gene name synonym)|uniprotkb:Arp2/3 complex 20 kDa subunit(gene name synonym) psi-mi:arpc5_human(display_long)|uniprotkb:ARPC5(gene name)|psi-mi:ARPC5(display_short)|uniprotkb:ARC16(gene name synonym)|uniprotkb:Arp2/3 complex 16 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476085|imex:IM-26985-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001185709.1|refseq:NP_005709.1|ensembl:ENSG00000241553(gene)|ensembl:ENST00000397261(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042995"(cell projection)|go:"GO:0045010"(actin nucleation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008384(ARP23 complex 20 kDa subunit)|interpro:IPR034666|mint:P59998|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|refseq:NP_001020130.1|refseq:NP_001020131.1|dip:DIP-33188N refseq:NP_005708.1|refseq:NP_001257368.1|dip:DIP-33144N|ensembl:ENSG00000162704(gene)|ensembl:ENST00000359856(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0014909"(smooth muscle cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0021769"(orbitofrontal cortex development)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030426"(growth cone)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035861"(site of double-strand break)|go:"GO:0051639"(actin filament network formation)|go:"GO:0061842"(microtubule organizing center localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097581"(lamellipodium organization)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR006789("ARP2/3 complex 16 kDa subunit (p16-Arc)")|interpro:IPR036743|mint:O15511|rcsb pdb:6UHC|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-6798695|reactome:R-HSA-8856828|reactome:R-HSA-9664422 - - comment:"author score: 384" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Iqe60TWfO3QBVOY+fOqZd9JWfIE9606 rogid:kfZQK6CXdREnQNI1h+GlQpB/gPI9606 rigid:A0zziuOH7bJ5Etu4YPD9X4jVTBc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59998 uniprotkb:P61160 intact:EBI-351872|uniprotkb:O15509|uniprotkb:C9JWM7|uniprotkb:E7ETI0|uniprotkb:Q6P0W5|uniprotkb:Q96QJ3|ensembl:ENSP00000380431|uniprotkb:F6TTL5 intact:EBI-353580|ensembl:ENSP00000260641|uniprotkb:O15142|uniprotkb:Q96C82|uniprotkb:B2RCP5|uniprotkb:D6W5F4|uniprotkb:E9PF41 psi-mi:arpc4_human(display_long)|uniprotkb:ARPC4(gene name)|psi-mi:ARPC4(display_short)|uniprotkb:ARC20(gene name synonym)|uniprotkb:Arp2/3 complex 20 kDa subunit(gene name synonym) psi-mi:arp2_human(display_long)|uniprotkb:ACTR2(gene name)|psi-mi:ACTR2(display_short)|uniprotkb:ARP2(gene name synonym)|uniprotkb:Actin-like protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476085|imex:IM-26985-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001185709.1|refseq:NP_005709.1|ensembl:ENSG00000241553(gene)|ensembl:ENST00000397261(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042995"(cell projection)|go:"GO:0045010"(actin nucleation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008384(ARP23 complex 20 kDa subunit)|interpro:IPR034666|mint:P59998|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|refseq:NP_001020130.1|refseq:NP_001020131.1|dip:DIP-33188N ensembl:ENSG00000138071(gene)|ensembl:ENST00000260641(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008306"(associative learning)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016344"(meiotic chromosome movement towards spindle pole)|go:"GO:0016482"(cytosolic transport)|go:"GO:0030027"(lamellipodium)|go:"GO:0030478"(actin cap)|go:"GO:0033206"(meiotic cytokinesis)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035861"(site of double-strand break)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0045471"(response to ethanol)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051653"(spindle localization)|go:"GO:0060271"(cilium assembly)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061825"(podosome core)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:1904813"(ficolin-1-rich granule lumen)|refseq:NP_001005386.1|refseq:NP_005713.1|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR004000(Actin/actin-like)|interpro:IPR020902|interpro:IPR043129|mint:P61160|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-6798695|reactome:R-HSA-8856828|reactome:R-HSA-9664422|dip:DIP-33165N - - comment:"author score: 436" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Iqe60TWfO3QBVOY+fOqZd9JWfIE9606 rogid:URQsZpIsMtsFZAnpLYDDvgKcPqA9606 rigid:A0zziuOH7bJ5Etu4YPD9X4jVTBc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59998 uniprotkb:Q92747 intact:EBI-351872|uniprotkb:O15509|uniprotkb:C9JWM7|uniprotkb:E7ETI0|uniprotkb:Q6P0W5|uniprotkb:Q96QJ3|ensembl:ENSP00000380431|uniprotkb:F6TTL5 intact:EBI-1020827|uniprotkb:Q7Z5U8|uniprotkb:Q86WU5|uniprotkb:Q8IXQ0|uniprotkb:A4D276|uniprotkb:D6W5S1|ensembl:ENSP00000262942|uniprotkb:B4DLQ7 psi-mi:arpc4_human(display_long)|uniprotkb:ARPC4(gene name)|psi-mi:ARPC4(display_short)|uniprotkb:ARC20(gene name synonym)|uniprotkb:Arp2/3 complex 20 kDa subunit(gene name synonym) psi-mi:arc1a_human(display_long)|uniprotkb:ARPC1A(gene name)|psi-mi:ARPC1A(display_short)|uniprotkb:SOP2L(gene name synonym)|uniprotkb:SOP2-like protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476085|imex:IM-26985-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001185709.1|refseq:NP_005709.1|ensembl:ENSG00000241553(gene)|ensembl:ENST00000397261(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042995"(cell projection)|go:"GO:0045010"(actin nucleation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008384(ARP23 complex 20 kDa subunit)|interpro:IPR034666|mint:P59998|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|refseq:NP_001020130.1|refseq:NP_001020131.1|dip:DIP-33188N refseq:NP_006400.2|ensembl:ENSG00000241685(gene)|ensembl:ENST00000262942(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017383(Actin-related protein 2/3 complex, subunit 1)|interpro:IPR030140|interpro:IPR036322|mint:Q92747|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|dip:DIP-33142N - - comment:"author score: 452" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Iqe60TWfO3QBVOY+fOqZd9JWfIE9606 rogid:ACqXC+XYl9R9Z7mHhpw7vt1SPu49606 rigid:A0zziuOH7bJ5Etu4YPD9X4jVTBc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P59998 uniprotkb:O15144 intact:EBI-351872|uniprotkb:O15509|uniprotkb:C9JWM7|uniprotkb:E7ETI0|uniprotkb:Q6P0W5|uniprotkb:Q96QJ3|ensembl:ENSP00000380431|uniprotkb:F6TTL5 intact:EBI-352356|uniprotkb:Q92801|uniprotkb:Q9P1D4|ensembl:ENSP00000295685|ensembl:ENSP00000327137 psi-mi:arpc4_human(display_long)|uniprotkb:ARPC4(gene name)|psi-mi:ARPC4(display_short)|uniprotkb:ARC20(gene name synonym)|uniprotkb:Arp2/3 complex 20 kDa subunit(gene name synonym) psi-mi:arpc2_human(display_long)|uniprotkb:ARPC2(gene name)|psi-mi:ARPC2(display_short)|uniprotkb:ARC34(gene name synonym)|uniprotkb:PRO2446(orf name)|uniprotkb:Arp2/3 complex 34 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476085|imex:IM-26985-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001185709.1|refseq:NP_005709.1|ensembl:ENSG00000241553(gene)|ensembl:ENST00000397261(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042995"(cell projection)|go:"GO:0045010"(actin nucleation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008384(ARP23 complex 20 kDa subunit)|interpro:IPR034666|mint:P59998|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|refseq:NP_001020130.1|refseq:NP_001020131.1|dip:DIP-33188N refseq:NP_005722.1|refseq:NP_690601.1|go:"GO:0005925"(focal adhesion)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036195"(muscle cell projection membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|interpro:IPR007188(Arp2/3 complex, 34kDa subunit p34-Arc)|interpro:IPR034666|mint:O15144|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|go:"GO:0005885"(Arp2/3 protein complex)|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|reactome:R-HSA-3928662|ensembl:ENSG00000163466(gene)|ensembl:ENST00000295685(transcript)|ensembl:ENST00000315717(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|dip:DIP-33197N - - comment:"author score: 478" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Iqe60TWfO3QBVOY+fOqZd9JWfIE9606 rogid:v5OozQTt614rvrBBoUavbAzjgZ49606 rigid:A0zziuOH7bJ5Etu4YPD9X4jVTBc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVP2 uniprotkb:P81605 intact:EBI-1055650|uniprotkb:Q53G51|uniprotkb:Q9NVZ0|ensembl:ENSP00000263382|ensembl:ENSP00000499863 intact:EBI-395625|uniprotkb:P58461|uniprotkb:A5JHP2|uniprotkb:A5JHP3|uniprotkb:Q53YJ2|ensembl:ENSP00000293371 psi-mi:asf1b_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog B(gene name synonym)|uniprotkb:CCG1-interacting factor A-II(gene name synonym)|uniprotkb:ASF1B(gene name)|psi-mi:ASF1B(display_short) psi-mi:dcd_human(display_long)|uniprotkb:AIDD(gene name synonym)|uniprotkb:DSEP(gene name synonym)|uniprotkb:Preproteolysin(gene name synonym)|uniprotkb:DCD(gene name)|psi-mi:DCD(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476220|imex:IM-26985-461 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060624.1|ensembl:ENSG00000105011(gene)|ensembl:ENSG00000288210(gene)|ensembl:ENST00000263382(transcript)|ensembl:ENST00000672225(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9NVP2|rcsb pdb:5BNX|rcsb pdb:5BO0|dip:DIP-29242N refseq:NP_444513.1|refseq:NP_001287783.1|ensembl:ENSG00000161634(gene)|ensembl:ENST00000293371(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008233"(peptidase activity)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR028130|interpro:IPR043557|mint:P81605|rcsb pdb:2KSG|rcsb pdb:2NDK|rcsb pdb:2YMK|rcsb pdb:6SHK|reactome:R-HSA-6803157 - caution:This sequence has been withdrawn from Uniprot. comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:gG2Px6QOw95EohRaaWivH7GrSr09606 rogid:M8PkKVWx98nhtd79ods05mqw8Ls9606 rigid:Ofa+rzrssTN88ZHqVp6vC4Z7u6A false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVP2 uniprotkb:Q01469 intact:EBI-1055650|uniprotkb:Q53G51|uniprotkb:Q9NVZ0|ensembl:ENSP00000263382|ensembl:ENSP00000499863 intact:EBI-1054073|uniprotkb:B2R4K0|ensembl:ENSP00000297258 psi-mi:asf1b_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog B(gene name synonym)|uniprotkb:CCG1-interacting factor A-II(gene name synonym)|uniprotkb:ASF1B(gene name)|psi-mi:ASF1B(display_short) psi-mi:fabp5_human(display_long)|uniprotkb:Epidermal-type fatty acid-binding protein(gene name synonym)|uniprotkb:Psoriasis-associated fatty acid-binding protein homolog(gene name synonym)|uniprotkb:FABP5(gene name)|psi-mi:FABP5(display_short)|uniprotkb:Fatty acid-binding protein, epidermal(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476220|imex:IM-26985-461 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060624.1|ensembl:ENSG00000105011(gene)|ensembl:ENSG00000288210(gene)|ensembl:ENST00000263382(transcript)|ensembl:ENST00000672225(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9NVP2|rcsb pdb:5BNX|rcsb pdb:5BO0|dip:DIP-29242N refseq:NP_001435.1|ensembl:ENSG00000164687(gene)|ensembl:ENST00000297258(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0008289"(lipid binding)|go:"GO:0008544"(epidermis development)|go:"GO:0010829"(negative regulation of glucose transmembrane transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031392"(regulation of prostaglandin biosynthetic process)|go:"GO:0035360"(positive regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099178"(regulation of retrograde trans-synaptic signaling by endocanabinoid)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990379"(lipid transport across blood-brain barrier)|interpro:IPR000463(Cytosolic fatty-acid binding)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR012674(Calycin)|interpro:IPR031259|mint:Q01469|rcsb pdb:1B56|rcsb pdb:1JJJ|rcsb pdb:4AZM|rcsb pdb:4AZR|rcsb pdb:4LKP|rcsb pdb:4LKT|rcsb pdb:5HZ5|rcsb pdb:5UR9|reactome:R-HSA-163560|reactome:R-HSA-5362517|reactome:R-HSA-6798695 - caution:This sequence has been withdrawn from Uniprot. comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:gG2Px6QOw95EohRaaWivH7GrSr09606 rogid:vxp81/mezHcm5oo27QOmAM8Y5dI9606 rigid:Ofa+rzrssTN88ZHqVp6vC4Z7u6A false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVP2 uniprotkb:P01040 intact:EBI-1055650|uniprotkb:Q53G51|uniprotkb:Q9NVZ0|ensembl:ENSP00000263382|ensembl:ENSP00000499863 intact:EBI-724303|ensembl:ENSP00000264474|uniprotkb:Q6IB90 psi-mi:asf1b_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog B(gene name synonym)|uniprotkb:CCG1-interacting factor A-II(gene name synonym)|uniprotkb:ASF1B(gene name)|psi-mi:ASF1B(display_short) psi-mi:cyta_human(display_long)|uniprotkb:Cystatin-AS(gene name synonym)|uniprotkb:Stefin-A(gene name synonym)|uniprotkb:CSTA(gene name)|psi-mi:CSTA(display_short)|uniprotkb:STF1(gene name synonym)|uniprotkb:STFA(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476220|imex:IM-26985-461 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060624.1|ensembl:ENSG00000105011(gene)|ensembl:ENSG00000288210(gene)|ensembl:ENST00000263382(transcript)|ensembl:ENST00000672225(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9NVP2|rcsb pdb:5BNX|rcsb pdb:5BO0|dip:DIP-29242N refseq:NP_005204.1|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR001713(Proteinase inhibitor I25A, stefin A)|mint:P01040|rcsb pdb:1CYU|rcsb pdb:1CYV|rcsb pdb:1DVC|rcsb pdb:1DVD|rcsb pdb:1GD3|rcsb pdb:1GD4|rcsb pdb:1N9J|rcsb pdb:1NB3|rcsb pdb:1NB5|rcsb pdb:3K9M|rcsb pdb:3KFQ|interpro:IPR018073|rcsb pdb:3KSE|reactome:R-HSA-6809371|ensembl:ENSG00000121552(gene)|ensembl:ENST00000264474(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002020"(protease binding)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0045861"(negative regulation of proteolysis) - caution:This sequence has been withdrawn from Uniprot. comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:gG2Px6QOw95EohRaaWivH7GrSr09606 rogid:SzbpyWUHlOtItIvffzuwhcqFsDI9606 rigid:Ofa+rzrssTN88ZHqVp6vC4Z7u6A false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVP2 uniprotkb:P68431 intact:EBI-1055650|uniprotkb:Q53G51|uniprotkb:Q9NVZ0|ensembl:ENSP00000263382|ensembl:ENSP00000499863 intact:EBI-79722|ensembl:ENSP00000352252|ensembl:ENSP00000358160|ensembl:ENSP00000366999|ensembl:ENSP00000480826|ensembl:ENSP00000482271|ensembl:ENSP00000483283|ensembl:ENSP00000484095|ensembl:ENSP00000484638|ensembl:ENSP00000484658|ensembl:ENSP00000484841|ensembl:ENSP00000489282|intact:EBI-1560041|uniprotkb:A0PJT7|uniprotkb:P02295|uniprotkb:P02296|uniprotkb:P16106|uniprotkb:Q6ISV8|uniprotkb:Q6NWP8|uniprotkb:Q6NWP9|uniprotkb:Q6NXU4|uniprotkb:Q71DJ3|uniprotkb:Q93081|uniprotkb:A5PLR1 psi-mi:asf1b_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog B(gene name synonym)|uniprotkb:CCG1-interacting factor A-II(gene name synonym)|uniprotkb:ASF1B(gene name)|psi-mi:ASF1B(display_short) psi-mi:h31_human(display_long)|uniprotkb:H3FA(gene name synonym)|uniprotkb:H3FL(gene name synonym)|uniprotkb:H3FD(gene name synonym)|uniprotkb:H3FI(gene name synonym)|uniprotkb:H3FH(gene name synonym)|uniprotkb:H3FK(gene name synonym)|uniprotkb:H3FF(gene name synonym)|uniprotkb:H3FJ(gene name synonym)|uniprotkb:H3FB(gene name synonym)|uniprotkb:Histone H3/a(gene name synonym)|uniprotkb:Histone H3/b(gene name synonym)|uniprotkb:Histone H3/c(gene name synonym)|uniprotkb:Histone H3/d(gene name synonym)|uniprotkb:Histone H3/f(gene name synonym)|uniprotkb:Histone H3/h(gene name synonym)|uniprotkb:Histone H3/i(gene name synonym)|uniprotkb:Histone H3/j(gene name synonym)|uniprotkb:Histone H3/k(gene name synonym)|uniprotkb:Histone H3/l(gene name synonym)|uniprotkb:H3C1(gene name)|psi-mi:H3C1(display_short)|uniprotkb:HIST1H3A(gene name synonym)|uniprotkb:H3C2(gene name)|psi-mi:H3C2(display_short)|uniprotkb:HIST1H3B(gene name synonym)|uniprotkb:H3C3(gene name)|psi-mi:H3C3(display_short)|uniprotkb:H3FC HIST1H3C(gene name synonym)|uniprotkb:H3C4(gene name)|psi-mi:H3C4(display_short)|uniprotkb:HIST1H3D(gene name synonym)|uniprotkb:H3C6(gene name)|psi-mi:H3C6(display_short)|uniprotkb:HIST1H3E(gene name synonym)|uniprotkb:H3C7(gene name)|psi-mi:H3C7(display_short)|uniprotkb:HIST1H3F(gene name synonym)|uniprotkb:H3C8(gene name)|psi-mi:H3C8(display_short)|uniprotkb:HIST1H3G(gene name synonym)|uniprotkb:H3C10(gene name)|psi-mi:H3C10(display_short)|uniprotkb:HIST1H3H(gene name synonym)|uniprotkb:H3C11(gene name)|psi-mi:H3C11(display_short)|uniprotkb:HIST1H3I(gene name synonym)|uniprotkb:H3C12(gene name)|psi-mi:H3C12(display_short)|uniprotkb:HIST1H3J(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476220|imex:IM-26985-461 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060624.1|ensembl:ENSG00000105011(gene)|ensembl:ENSG00000288210(gene)|ensembl:ENST00000263382(transcript)|ensembl:ENST00000672225(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9NVP2|rcsb pdb:5BNX|rcsb pdb:5BO0|dip:DIP-29242N rcsb pdb:4TN7|rcsb pdb:4U68|rcsb pdb:4UP0|rcsb pdb:4UY4|rcsb pdb:4X3K|rcsb pdb:4Y6L|rcsb pdb:4YHP|rcsb pdb:4YHZ|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z0R|rcsb pdb:4Z2M|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:4QBS|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B31|rcsb pdb:5C11|rcsb pdb:5C13|rcsb pdb:5C3I|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5D6Y|rcsb pdb:5DAH|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5FFV|rcsb pdb:5GH9|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5H6Q|rcsb pdb:5H6R|rcsb pdb:5HJB|rcsb pdb:5HJC|rcsb pdb:5HJD|rcsb pdb:5HYN|rcsb pdb:5IQL|rcsb pdb:5J3V|rcsb pdb:5J9S|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5B2J|rcsb pdb:5JRG|rcsb pdb:5KJH|rcsb pdb:5KJI|rcsb pdb:5KKL|rcsb pdb:5LUG|rcsb pdb:5M5G|rcsb pdb:5MR8|rcsb pdb:5NNC|rcsb pdb:5OY3|rcsb pdb:5SVX|rcsb pdb:5SVY|rcsb pdb:5SZB|rcsb pdb:5SZC|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5T1G|rcsb pdb:5T1I|rcsb pdb:5T8R|rcsb pdb:5TBN|rcsb pdb:5TDR|rcsb pdb:5TDW|rcsb pdb:5U2J|rcsb pdb:5V21|rcsb pdb:5V22|rcsb pdb:5VA6|rcsb pdb:5VAB|rcsb pdb:5VGE|rcsb pdb:5VNB|rcsb pdb:5NND|rcsb pdb:5WLE|rcsb pdb:5WVO|rcsb pdb:5WXG|rcsb pdb:5WXH|rcsb pdb:5WYI|rcsb pdb:5X60|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5XFQ|rcsb pdb:5XFR|rcsb pdb:5XNV|rcsb pdb:5XTZ|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Y20|rcsb pdb:5Y2F|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:6AXJ|rcsb pdb:6AZE|rcsb pdb:6BHD|rcsb pdb:6BHE|rcsb pdb:6BHG|rcsb pdb:6BHH|rcsb pdb:6BHI|rcsb pdb:6D07|rcsb pdb:6D08|rcsb pdb:6E83|rcsb pdb:6E86|rcsb pdb:5WFC|rcsb pdb:6F6D|rcsb pdb:6HTS|rcsb pdb:6IEU|rcsb pdb:6IIS|rcsb pdb:6IIT|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6JXD|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6LS6|rcsb pdb:6LSD|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MIL|rcsb pdb:6MIM|rcsb pdb:6MIN|rcsb pdb:6MIO|rcsb pdb:6MIQ|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6HKT|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2H|rcsb pdb:6V2K|rcsb pdb:6V3N|rcsb pdb:6V41|rcsb pdb:6V92|rcsb pdb:6VIL|rcsb pdb:6WAV|rcsb pdb:6WW4|rcsb pdb:6YIF|rcsb pdb:6YIH|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:6R92|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7KLR|rcsb pdb:7LYC|reactome:R-HSA-1266695|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|ensembl:ENSG00000197153(gene)|ensembl:ENSG00000197409(gene)|ensembl:ENSG00000273983(gene)|ensembl:ENSG00000274750(gene)|ensembl:ENSG00000275379(gene)|ensembl:ENSG00000275714(gene)|ensembl:ENSG00000277775(gene)|ensembl:ENSG00000278828(gene)|ensembl:ENSG00000286522(gene)|ensembl:ENSG00000287080(gene)|ensembl:ENST00000356476(transcript)|ensembl:ENST00000359303(transcript)|ensembl:ENST00000369163(transcript)|ensembl:ENST00000612966(transcript)|ensembl:ENST00000613854(transcript)|ensembl:ENST00000614378(transcript)|ensembl:ENST00000614911(transcript)|ensembl:ENST00000616365(transcript)|ensembl:ENST00000618052(transcript)|ensembl:ENST00000621411(transcript)|ensembl:ENST00000634733(transcript)|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-3247509|reactome:R-HSA-9710421|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060968"(obsolete regulation of gene silencing)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|interpro:IPR009072(Histone-fold)|mint:P68431|rcsb pdb:1CS9|rcsb pdb:1CT6|rcsb pdb:1O9S|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|rcsb pdb:1Q3L|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|rcsb pdb:2B2T|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|rcsb pdb:2B2U|rcsb pdb:2B2V|rcsb pdb:2B2W|rcsb pdb:2C1J|rcsb pdb:2C1N|go:"GO:0016020"(membrane)|rcsb pdb:2CO0|rcsb pdb:2CV5|rcsb pdb:2FSA|rcsb pdb:2KWJ|rcsb pdb:2KWK|rcsb pdb:2L75|rcsb pdb:2LBM|rcsb pdb:2LGG|rcsb pdb:2M0O|reactome:R-HSA-983231|reactome:R-HSA-977225|rcsb pdb:2NDG|rcsb pdb:2OQ6|rcsb pdb:2OT7|rcsb pdb:2OX0|rcsb pdb:2RI7|rcsb pdb:2RR4|rcsb pdb:2UXN|rcsb pdb:2V85|rcsb pdb:2V89|rcsb pdb:2VNF|rcsb pdb:2VPG|rcsb pdb:2X0L|rcsb pdb:3A1B|rcsb pdb:2NDF|rcsb pdb:3AFA|rcsb pdb:3AVR|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3B95|rcsb pdb:3FDT|rcsb pdb:3KMT|rcsb pdb:3KQI|rcsb pdb:3LQI|rcsb pdb:3LQJ|rcsb pdb:3MP1|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O37|rcsb pdb:3QJ6|rcsb pdb:3RIG|rcsb pdb:3RIY|rcsb pdb:3SOU|rcsb pdb:3SOW|rcsb pdb:3U31|rcsb pdb:3U3D|rcsb pdb:3U4S|rcsb pdb:3U5N|rcsb pdb:3U5O|rcsb pdb:3AZK|rcsb pdb:3U5P|rcsb pdb:3UEE|rcsb pdb:3UEF|rcsb pdb:3UII|rcsb pdb:3UIK|rcsb pdb:3V43|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:3ZG6|rcsb pdb:3ZVY|rcsb pdb:4A0J|rcsb pdb:4A0N|rcsb pdb:4A7J|rcsb pdb:3UIG|rcsb pdb:4BD3|rcsb pdb:4C1Q|rcsb pdb:4F4U|rcsb pdb:4F56|rcsb pdb:4FWF|rcsb pdb:4HON|rcsb pdb:4I51|rcsb pdb:4L7X|rcsb pdb:4LK9|rcsb pdb:4LKA|rcsb pdb:4LLB|rcsb pdb:4LXL|rcsb pdb:4N4H|rcsb pdb:4QBQ|rcsb pdb:4QBR|refseq:NP_003520.1|refseq:NP_003521.2|refseq:NP_003522.1|refseq:NP_003523.1|refseq:NP_003524.1|refseq:NP_003525.1|refseq:NP_003526.1|refseq:NP_003527.1|refseq:NP_003528.1|refseq:NP_066298.1|dip:DIP-29371N - caution:This sequence has been withdrawn from Uniprot. comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:gG2Px6QOw95EohRaaWivH7GrSr09606 rogid:ood0OohxZHuhsWZtO7U7GMc+LwM9606 rigid:Ofa+rzrssTN88ZHqVp6vC4Z7u6A false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVP2 uniprotkb:O14929 intact:EBI-1055650|uniprotkb:Q53G51|uniprotkb:Q9NVZ0|ensembl:ENSP00000263382|ensembl:ENSP00000499863 intact:EBI-2339359|uniprotkb:Q53SU4|uniprotkb:Q53QF0|uniprotkb:Q49A44|uniprotkb:Q6P594|uniprotkb:Q8WWB9|ensembl:ENSP00000264108 psi-mi:asf1b_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog B(gene name synonym)|uniprotkb:CCG1-interacting factor A-II(gene name synonym)|uniprotkb:ASF1B(gene name)|psi-mi:ASF1B(display_short) psi-mi:hat1_human(display_long)|uniprotkb:HAT1(gene name)|psi-mi:HAT1(display_short)|uniprotkb:KAT1(gene name synonym)|uniprotkb:Histone acetyltransferase 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476220|imex:IM-26985-461 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060624.1|ensembl:ENSG00000105011(gene)|ensembl:ENSG00000288210(gene)|ensembl:ENST00000263382(transcript)|ensembl:ENST00000672225(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9NVP2|rcsb pdb:5BNX|rcsb pdb:5BO0|dip:DIP-29242N refseq:NP_003633.1|dip:DIP-52811N|ensembl:ENSG00000128708(gene)|ensembl:ENST00000264108(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006323"(DNA packaging)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006348"|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0007584"(response to nutrient)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR013523(Histone acetyltransferase HAT1, C-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017380(Histone acetyltransferase type B, catalytic subunit)|interpro:IPR019467|interpro:IPR037113|mint:O14929|rcsb pdb:2P0W|rcsb pdb:6VO5|reactome:R-HSA-3214847 - caution:This sequence has been withdrawn from Uniprot. comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:gG2Px6QOw95EohRaaWivH7GrSr09606 rogid:80KgRaid3NeRfAUdTHMQ/r0VuGo9606 rigid:Ofa+rzrssTN88ZHqVp6vC4Z7u6A false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVP2 uniprotkb:Q16576 intact:EBI-1055650|uniprotkb:Q53G51|uniprotkb:Q9NVZ0|ensembl:ENSP00000263382|ensembl:ENSP00000499863 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 psi-mi:asf1b_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog B(gene name synonym)|uniprotkb:CCG1-interacting factor A-II(gene name synonym)|uniprotkb:ASF1B(gene name)|psi-mi:ASF1B(display_short) psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476220|imex:IM-26985-461 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060624.1|ensembl:ENSG00000105011(gene)|ensembl:ENSG00000288210(gene)|ensembl:ENST00000263382(transcript)|ensembl:ENST00000672225(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9NVP2|rcsb pdb:5BNX|rcsb pdb:5BO0|dip:DIP-29242N refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N - caution:This sequence has been withdrawn from Uniprot. comment:"author score: 27" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:gG2Px6QOw95EohRaaWivH7GrSr09606 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rigid:Ofa+rzrssTN88ZHqVp6vC4Z7u6A false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVP2 uniprotkb:Q8IWY9 intact:EBI-1055650|uniprotkb:Q53G51|uniprotkb:Q9NVZ0|ensembl:ENSP00000263382|ensembl:ENSP00000499863 intact:EBI-726307|uniprotkb:Q6NYD0|uniprotkb:Q7Z7L5|uniprotkb:Q969N3|ensembl:ENSP00000348564 psi-mi:asf1b_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog B(gene name synonym)|uniprotkb:CCG1-interacting factor A-II(gene name synonym)|uniprotkb:ASF1B(gene name)|psi-mi:ASF1B(display_short) psi-mi:cdan1_human(display_long)|uniprotkb:CDAN1(gene name)|psi-mi:CDAN1(display_short)|uniprotkb:UNQ664/PRO1295(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476220|imex:IM-26985-461 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060624.1|ensembl:ENSG00000105011(gene)|ensembl:ENSG00000288210(gene)|ensembl:ENST00000263382(transcript)|ensembl:ENST00000672225(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9NVP2|rcsb pdb:5BNX|rcsb pdb:5BO0|dip:DIP-29242N refseq:NP_612486.2|dip:DIP-24225N|ensembl:ENSG00000140326(gene)|ensembl:ENST00000356231(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0008104"(protein localization)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031497"(chromatin assembly)|interpro:IPR028171|interpro:IPR040031|mint:Q8IWY9 - caution:This sequence has been withdrawn from Uniprot. comment:"author score: 27" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:gG2Px6QOw95EohRaaWivH7GrSr09606 rogid:Hbm36aMIq0BwSxCOLnxRl3vyYZY9606 rigid:Ofa+rzrssTN88ZHqVp6vC4Z7u6A false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVP2 uniprotkb:P49736 intact:EBI-1055650|uniprotkb:Q53G51|uniprotkb:Q9NVZ0|ensembl:ENSP00000263382|ensembl:ENSP00000499863 intact:EBI-374819|uniprotkb:Q14577|uniprotkb:Q15023|uniprotkb:Q8N2V1|uniprotkb:Q969W7|uniprotkb:Q96AE1|uniprotkb:Q9BRM7|ensembl:ENSP00000265056 psi-mi:asf1b_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog B(gene name synonym)|uniprotkb:CCG1-interacting factor A-II(gene name synonym)|uniprotkb:ASF1B(gene name)|psi-mi:ASF1B(display_short) psi-mi:mcm2_human(display_long)|uniprotkb:MCM2(gene name)|psi-mi:MCM2(display_short)|uniprotkb:BM28(gene name synonym)|uniprotkb:CDCL1(gene name synonym)|uniprotkb:KIAA0030(gene name synonym)|uniprotkb:Minichromosome maintenance protein 2 homolog(gene name synonym)|uniprotkb:Nuclear protein BM28(gene name synonym)|uniprotkb:CCNL1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476220|imex:IM-26985-461 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060624.1|ensembl:ENSG00000105011(gene)|ensembl:ENSG00000288210(gene)|ensembl:ENST00000263382(transcript)|ensembl:ENST00000672225(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9NVP2|rcsb pdb:5BNX|rcsb pdb:5BO0|dip:DIP-29242N ensembl:ENSG00000073111(gene)|ensembl:ENST00000265056(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006915"(apoptotic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0042393"(histone binding)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090102"(cochlea development)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P49736|rcsb pdb:4UUZ|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5JA4|rcsb pdb:6XTX|rcsb pdb:6XTY|rcsb pdb:6YA7|rcsb pdb:7CIZ|rcsb pdb:7CJ0|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|refseq:NP_004517.2|dip:DIP-31732N - caution:This sequence has been withdrawn from Uniprot. comment:"author score: 27" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:gG2Px6QOw95EohRaaWivH7GrSr09606 rogid:Jt9ODNyJBwtwQ0pb/+X46vtHfE09606 rigid:Ofa+rzrssTN88ZHqVp6vC4Z7u6A false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVP2 uniprotkb:Q9BW71 intact:EBI-1055650|uniprotkb:Q53G51|uniprotkb:Q9NVZ0|ensembl:ENSP00000263382|ensembl:ENSP00000499863 intact:EBI-723624|uniprotkb:O75707|uniprotkb:O75708|ensembl:ENSP00000279392|uniprotkb:H3BSR3 psi-mi:asf1b_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog B(gene name synonym)|uniprotkb:CCG1-interacting factor A-II(gene name synonym)|uniprotkb:ASF1B(gene name)|psi-mi:ASF1B(display_short) psi-mi:hirp3_human(display_long)|uniprotkb:HIRIP3(gene name)|psi-mi:HIRIP3(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476220|imex:IM-26985-461 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060624.1|ensembl:ENSG00000105011(gene)|ensembl:ENSG00000288210(gene)|ensembl:ENST00000263382(transcript)|ensembl:ENST00000672225(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9NVP2|rcsb pdb:5BNX|rcsb pdb:5BO0|dip:DIP-29242N refseq:NP_003600.2|ensembl:ENSG00000149929(gene)|ensembl:ENST00000279392(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006333"(chromatin assembly or disassembly)|interpro:IPR019098|interpro:IPR037647|mint:Q9BW71|refseq:NP_001184252.1 - caution:This sequence has been withdrawn from Uniprot. comment:"author score: 30" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:gG2Px6QOw95EohRaaWivH7GrSr09606 rogid:NaB5i2oZ7MCfCvw+Vc0eC6u5B+s9606 rigid:Ofa+rzrssTN88ZHqVp6vC4Z7u6A false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVP2 uniprotkb:Q6ZU65 intact:EBI-1055650|uniprotkb:Q53G51|uniprotkb:Q9NVZ0|ensembl:ENSP00000263382|ensembl:ENSP00000499863 intact:EBI-9661773|uniprotkb:A4D1S2|uniprotkb:Q2YDY4|uniprotkb:Q6P1K0|uniprotkb:Q86XN9|uniprotkb:Q8N7D1|ensembl:ENSP00000418648 psi-mi:asf1b_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog B(gene name synonym)|uniprotkb:CCG1-interacting factor A-II(gene name synonym)|uniprotkb:ASF1B(gene name)|psi-mi:ASF1B(display_short) psi-mi:ubn2_human(display_long)|uniprotkb:UBN2(gene name)|psi-mi:UBN2(display_short)|uniprotkb:KIAA2030(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476220|imex:IM-26985-461 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060624.1|ensembl:ENSG00000105011(gene)|ensembl:ENSG00000288210(gene)|ensembl:ENST00000263382(transcript)|ensembl:ENST00000672225(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9NVP2|rcsb pdb:5BNX|rcsb pdb:5BO0|dip:DIP-29242N ensembl:ENSP00000418648|refseq:NP_775840.3|dip:DIP-47312N|ensembl:ENSG00000157741(gene)|ensembl:ENST00000473989(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|interpro:IPR014840("Histone promoter control 2 (HPC2)")|interpro:IPR026943|interpro:IPR026947|mint:Q6ZU65 - caution:This sequence has been withdrawn from Uniprot. comment:"author score: 32" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:gG2Px6QOw95EohRaaWivH7GrSr09606 rogid:Z45kNtHT1rLdgqkCTrcRGD7L2749606 rigid:Ofa+rzrssTN88ZHqVp6vC4Z7u6A false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVP2 uniprotkb:P62805 intact:EBI-1055650|uniprotkb:Q53G51|uniprotkb:Q9NVZ0|ensembl:ENSP00000263382|ensembl:ENSP00000499863 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:asf1b_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog B(gene name synonym)|uniprotkb:CCG1-interacting factor A-II(gene name synonym)|uniprotkb:ASF1B(gene name)|psi-mi:ASF1B(display_short) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476220|imex:IM-26985-461 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060624.1|ensembl:ENSG00000105011(gene)|ensembl:ENSG00000288210(gene)|ensembl:ENST00000263382(transcript)|ensembl:ENST00000672225(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9NVP2|rcsb pdb:5BNX|rcsb pdb:5BO0|dip:DIP-29242N ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - caution:This sequence has been withdrawn from Uniprot. comment:"author score: 32" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:gG2Px6QOw95EohRaaWivH7GrSr09606 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 rigid:Ofa+rzrssTN88ZHqVp6vC4Z7u6A false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVP2 uniprotkb:Q9Y6J0 intact:EBI-1055650|uniprotkb:Q53G51|uniprotkb:Q9NVZ0|ensembl:ENSP00000263382|ensembl:ENSP00000499863 intact:EBI-2795712|uniprotkb:Q9Y460|uniprotkb:G5E9F3|uniprotkb:Q6PHY0|intact:EBI-28988204|ensembl:ENSP00000263119|ensembl:ENSP00000381364 psi-mi:asf1b_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog B(gene name synonym)|uniprotkb:CCG1-interacting factor A-II(gene name synonym)|uniprotkb:ASF1B(gene name)|psi-mi:ASF1B(display_short) psi-mi:cabin_human(display_long)|uniprotkb:CABIN1(gene name)|psi-mi:CABIN1(display_short)|uniprotkb:KIAA0330(gene name synonym)|uniprotkb:Calcineurin inhibitor(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476220|imex:IM-26985-461 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060624.1|ensembl:ENSG00000105011(gene)|ensembl:ENSG00000288210(gene)|ensembl:ENST00000263382(transcript)|ensembl:ENST00000672225(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9NVP2|rcsb pdb:5BNX|rcsb pdb:5BO0|dip:DIP-29242N refseq:NP_001186210.1|refseq:NP_001188358.1|refseq:NP_036427.1|refseq:XP_016884172.1|ensembl:ENSP00000263119|ensembl:ENSP00000381364|ensembl:ENST00000405822|ensembl:ENSP00000384694|ensembl:ENSG00000099991(gene)|ensembl:ENST00000263119(transcript)|ensembl:ENST00000398319(transcript)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016235"(aggresome)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015134(MEF2 binding)|interpro:IPR019734|interpro:IPR033053|mint:Q9Y6J0|rcsb pdb:1N6J|reactome:R-HSA-2559584 - caution:This sequence has been withdrawn from Uniprot. comment:"author score: 32" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:gG2Px6QOw95EohRaaWivH7GrSr09606 rogid:b4BLYv/aw7zl2SZQXLXAQr+RmY49606 rigid:Ofa+rzrssTN88ZHqVp6vC4Z7u6A false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVP2 uniprotkb:P54198 intact:EBI-1055650|uniprotkb:Q53G51|uniprotkb:Q9NVZ0|ensembl:ENSP00000263382|ensembl:ENSP00000499863 intact:EBI-372342|uniprotkb:Q05BU9|uniprotkb:Q8IXN2|ensembl:ENSP00000263208 psi-mi:asf1b_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog B(gene name synonym)|uniprotkb:CCG1-interacting factor A-II(gene name synonym)|uniprotkb:ASF1B(gene name)|psi-mi:ASF1B(display_short) psi-mi:hira_human(display_long)|uniprotkb:HIRA(gene name)|psi-mi:HIRA(display_short)|uniprotkb:TUP1-like enhancer of split protein 1(gene name synonym)|uniprotkb:DGCR1(gene name synonym)|uniprotkb:HIR(gene name synonym)|uniprotkb:TUPLE1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476220|imex:IM-26985-461 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060624.1|ensembl:ENSG00000105011(gene)|ensembl:ENSG00000288210(gene)|ensembl:ENST00000263382(transcript)|ensembl:ENST00000672225(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9NVP2|rcsb pdb:5BNX|rcsb pdb:5BO0|dip:DIP-29242N refseq:NP_003316.3|dip:DIP-29240N|ensembl:ENSG00000100084(gene)|ensembl:ENST00000263208(transcript)|go:"GO:0000417"(HIR complex)|go:"GO:0000785"(chromatin)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0016605"(PML body)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR011494(TUP1-like enhancer of split)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031120|interpro:IPR036322|mint:P54198|rcsb pdb:2I32|rcsb pdb:5YJE|reactome:R-HSA-2559584 - caution:This sequence has been withdrawn from Uniprot. comment:"author score: 42" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:gG2Px6QOw95EohRaaWivH7GrSr09606 rogid:en6l6z4CNWhF4Wlj5ou4DDTfETg9606 rigid:Ofa+rzrssTN88ZHqVp6vC4Z7u6A false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVP2 uniprotkb:Q86UE8 intact:EBI-1055650|uniprotkb:Q53G51|uniprotkb:Q9NVZ0|ensembl:ENSP00000263382|ensembl:ENSP00000499863 intact:EBI-1047967|uniprotkb:Q9UKI7|uniprotkb:Q9Y4F7|uniprotkb:D3DU07|intact:EBI-28969484|ensembl:ENSP00000316512 psi-mi:asf1b_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog B(gene name synonym)|uniprotkb:CCG1-interacting factor A-II(gene name synonym)|uniprotkb:ASF1B(gene name)|psi-mi:ASF1B(display_short) psi-mi:tlk2_human(display_long)|uniprotkb:Tousled-like kinase 2(gene name synonym)|uniprotkb:PKU-alpha(gene name synonym)|uniprotkb:TLK2(gene name)|psi-mi:TLK2(display_short)|uniprotkb:HsHPK(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476220|imex:IM-26985-461 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060624.1|ensembl:ENSG00000105011(gene)|ensembl:ENSG00000288210(gene)|ensembl:ENST00000263382(transcript)|ensembl:ENST00000672225(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9NVP2|rcsb pdb:5BNX|rcsb pdb:5BO0|dip:DIP-29242N refseq:NP_006843.2|refseq:NP_001271262.1|ensembl:ENSP00000316512|ensembl:ENST00000343388|ensembl:ENSP00000340800|ensembl:ENST00000346027|ensembl:ENSP00000275780|ensembl:ENST00000682085|ensembl:ENSP00000506744|ensembl:ENST00000683104|ensembl:ENSP00000508242|refseq:XP_011522518.1|refseq:XP_011522519.1|refseq:XP_011522524.1|ensembl:ENSG00000146872(gene)|ensembl:ENST00000326270(transcript)|go:"GO:0001672"(regulation of chromatin assembly or disassembly)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005882"(intermediate filament)|go:"GO:0006325"(chromatin organization)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR027086|mint:Q86UE8|rcsb pdb:5O0Y|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|refseq:XP_016879533.1|refseq:XP_016879535.1|refseq:XP_016879536.1|refseq:XP_016879540.1|refseq:XP_016879541.1|refseq:XP_016879542.1|refseq:NP_001271292.1 - caution:This sequence has been withdrawn from Uniprot. comment:"author score: 43" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:gG2Px6QOw95EohRaaWivH7GrSr09606 rogid:K1u8NeS9j5URs6/bUJn47WPk5Ss9606 rigid:Ofa+rzrssTN88ZHqVp6vC4Z7u6A false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVP2 uniprotkb:Q9NPG3 intact:EBI-1055650|uniprotkb:Q53G51|uniprotkb:Q9NVZ0|ensembl:ENSP00000263382|ensembl:ENSP00000499863 intact:EBI-2880187|ensembl:ENSP00000262376|ensembl:ENSP00000379894|uniprotkb:B7Z6D3|uniprotkb:Q13079|uniprotkb:Q9P1P7|uniprotkb:D3DUE8 psi-mi:asf1b_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog B(gene name synonym)|uniprotkb:CCG1-interacting factor A-II(gene name synonym)|uniprotkb:ASF1B(gene name)|psi-mi:ASF1B(display_short) psi-mi:ubn1_human(display_long)|uniprotkb:UBN1(gene name)|psi-mi:UBN1(display_short)|uniprotkb:HIRA-binding protein(gene name synonym)|uniprotkb:Protein VT4(gene name synonym)|uniprotkb:Ubiquitously expressed nuclear protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476220|imex:IM-26985-461 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060624.1|ensembl:ENSG00000105011(gene)|ensembl:ENSG00000288210(gene)|ensembl:ENST00000263382(transcript)|ensembl:ENST00000672225(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9NVP2|rcsb pdb:5BNX|rcsb pdb:5BO0|dip:DIP-29242N ensembl:ENSG00000118900(gene)|ensembl:ENST00000262376(transcript)|ensembl:ENST00000396658(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0034451"(centriolar satellite)|interpro:IPR014840("Histone promoter control 2 (HPC2)")|interpro:IPR026936|interpro:IPR026947|mint:Q9NPG3|rcsb pdb:4ZBJ|reactome:R-HSA-2559584|go:"GO:0005654"(nucleoplasm)|refseq:NP_001072982.1|refseq:XP_016878678.1|refseq:NP_001275585.1|ensembl:ENSP00000262376|ensembl:ENSP00000379894|ensembl:ENST00000590769|ensembl:ENSP00000468740 - caution:This sequence has been withdrawn from Uniprot. comment:"author score: 43" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:gG2Px6QOw95EohRaaWivH7GrSr09606 rogid:IT0lTmzNcbWFQVVD5DfATSqxjwg9606 rigid:Ofa+rzrssTN88ZHqVp6vC4Z7u6A false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVP2 uniprotkb:P49321 intact:EBI-1055650|uniprotkb:Q53G51|uniprotkb:Q9NVZ0|ensembl:ENSP00000263382|ensembl:ENSP00000499863 intact:EBI-716205|uniprotkb:Q53GW5|uniprotkb:Q5T625|uniprotkb:Q5T622|uniprotkb:Q96A69|uniprotkb:Q9BTW2|uniprotkb:A8K6H2|uniprotkb:B4DQP3|uniprotkb:F5H3J2|uniprotkb:D3DQ07|intact:EBI-28989159|ensembl:ENSP00000255120 psi-mi:asf1b_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog B(gene name synonym)|uniprotkb:CCG1-interacting factor A-II(gene name synonym)|uniprotkb:ASF1B(gene name)|psi-mi:ASF1B(display_short) psi-mi:nasp_human(display_long)|uniprotkb:NASP(gene name)|psi-mi:NASP(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476220|imex:IM-26985-461 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060624.1|ensembl:ENSG00000105011(gene)|ensembl:ENSG00000288210(gene)|ensembl:ENST00000263382(transcript)|ensembl:ENST00000672225(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9NVP2|rcsb pdb:5BNX|rcsb pdb:5BO0|dip:DIP-29242N refseq:NP_001182122.1|refseq:NP_002473.2|refseq:NP_689511.2|ensembl:ENSG00000132780(gene)|ensembl:ENST00000350030(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0001824"(blastocyst development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0008584"(male gonad development)|go:"GO:0015031"(protein transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033574"(response to testosterone)|go:"GO:0034080"(CENP-A containing chromatin assembly)|go:"GO:0042393"(histone binding)|go:"GO:0043486"(histone exchange)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019544|interpro:IPR019734|mint:P49321|ensembl:ENSP00000255120|ensembl:ENST00000351223|ensembl:ENSP00000255121|ensembl:ENST00000537798|ensembl:ENSP00000438871|refseq:XP_005270945.1|dip:DIP-47269N - caution:This sequence has been withdrawn from Uniprot. comment:"author score: 56" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:gG2Px6QOw95EohRaaWivH7GrSr09606 rogid:8BOknyp+vOh6NF+fXZPYbbqFbH49606 rigid:Ofa+rzrssTN88ZHqVp6vC4Z7u6A false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y294 uniprotkb:Q13112 intact:EBI-749553|uniprotkb:Q6IA08|uniprotkb:Q9P014|ensembl:ENSP00000229595 intact:EBI-1052944|uniprotkb:Q99548|ensembl:ENSP00000315700 psi-mi:asf1a_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog A(gene name synonym)|uniprotkb:CCG1-interacting factor A(gene name synonym)|uniprotkb:ASF1A(gene name)|psi-mi:ASF1A(display_short)|uniprotkb:CGI-98(orf name)|uniprotkb:HSPC146(orf name) psi-mi:caf1b_human(display_long)|uniprotkb:Chromatin assembly factor I p60 subunit(gene name synonym)|uniprotkb:M-phase phosphoprotein 7(gene name synonym)|uniprotkb:CHAF1B(gene name)|psi-mi:CHAF1B(display_short)|uniprotkb:CAF1A(gene name synonym)|uniprotkb:CAF1P60(gene name synonym)|uniprotkb:MPHOSPH7(gene name synonym)|uniprotkb:MPP7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476151|imex:IM-26985-145 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_054753.1|dip:DIP-29241N|ensembl:ENSG00000111875(gene)|ensembl:ENST00000229595(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0042692"(muscle cell differentiation)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9Y294|rcsb pdb:1TEY|rcsb pdb:2I32|rcsb pdb:2IIJ|rcsb pdb:2IO5|rcsb pdb:3AAD|rcsb pdb:5C3I|rcsb pdb:6F0G|rcsb pdb:6F0H|rcsb pdb:6ZUF|reactome:R-HSA-2559584|rcsb pdb:6F0F refseq:NP_005432.1|dip:DIP-29243N|ensembl:ENSG00000159259(gene)|ensembl:ENST00000314103(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR029129|interpro:IPR036322|mint:Q13112|refseq:XP_016883966.1|refseq:XP_016883967.1 - caution:This sequence has been withdrawn from Uniprot. comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:rIMptRSOYD+wfp0dMEHjhNNsHXQ9606 rogid:VVbW9mpUGYMRPxvlEk9FERHIsJs9606 rigid:QRaYY4EbPeK4i/HGiVrIcubpvQo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y294 uniprotkb:P49736 intact:EBI-749553|uniprotkb:Q6IA08|uniprotkb:Q9P014|ensembl:ENSP00000229595 intact:EBI-374819|uniprotkb:Q14577|uniprotkb:Q15023|uniprotkb:Q8N2V1|uniprotkb:Q969W7|uniprotkb:Q96AE1|uniprotkb:Q9BRM7|ensembl:ENSP00000265056 psi-mi:asf1a_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog A(gene name synonym)|uniprotkb:CCG1-interacting factor A(gene name synonym)|uniprotkb:ASF1A(gene name)|psi-mi:ASF1A(display_short)|uniprotkb:CGI-98(orf name)|uniprotkb:HSPC146(orf name) psi-mi:mcm2_human(display_long)|uniprotkb:MCM2(gene name)|psi-mi:MCM2(display_short)|uniprotkb:BM28(gene name synonym)|uniprotkb:CDCL1(gene name synonym)|uniprotkb:KIAA0030(gene name synonym)|uniprotkb:Minichromosome maintenance protein 2 homolog(gene name synonym)|uniprotkb:Nuclear protein BM28(gene name synonym)|uniprotkb:CCNL1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476151|imex:IM-26985-145 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_054753.1|dip:DIP-29241N|ensembl:ENSG00000111875(gene)|ensembl:ENST00000229595(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0042692"(muscle cell differentiation)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9Y294|rcsb pdb:1TEY|rcsb pdb:2I32|rcsb pdb:2IIJ|rcsb pdb:2IO5|rcsb pdb:3AAD|rcsb pdb:5C3I|rcsb pdb:6F0G|rcsb pdb:6F0H|rcsb pdb:6ZUF|reactome:R-HSA-2559584|rcsb pdb:6F0F ensembl:ENSG00000073111(gene)|ensembl:ENST00000265056(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006915"(apoptotic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0042393"(histone binding)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090102"(cochlea development)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P49736|rcsb pdb:4UUZ|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5JA4|rcsb pdb:6XTX|rcsb pdb:6XTY|rcsb pdb:6YA7|rcsb pdb:7CIZ|rcsb pdb:7CJ0|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|refseq:NP_004517.2|dip:DIP-31732N - caution:This sequence has been withdrawn from Uniprot. comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:rIMptRSOYD+wfp0dMEHjhNNsHXQ9606 rogid:Jt9ODNyJBwtwQ0pb/+X46vtHfE09606 rigid:QRaYY4EbPeK4i/HGiVrIcubpvQo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y294 uniprotkb:Q9HCY8 intact:EBI-749553|uniprotkb:Q6IA08|uniprotkb:Q9P014|ensembl:ENSP00000229595 intact:EBI-751842|uniprotkb:Q5RHT0|ensembl:ENSP00000340463|ensembl:ENSP00000357690|ensembl:ENSP00000357691|ensembl:ENSP00000420296 psi-mi:asf1a_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog A(gene name synonym)|uniprotkb:CCG1-interacting factor A(gene name synonym)|uniprotkb:ASF1A(gene name)|psi-mi:ASF1A(display_short)|uniprotkb:CGI-98(orf name)|uniprotkb:HSPC146(orf name) psi-mi:s10ae_human(display_long)|uniprotkb:S100 calcium-binding protein A14(gene name synonym)|uniprotkb:S100A14(gene name)|psi-mi:S100A14(display_short)|uniprotkb:S100A15(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476151|imex:IM-26985-145 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_054753.1|dip:DIP-29241N|ensembl:ENSG00000111875(gene)|ensembl:ENST00000229595(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0042692"(muscle cell differentiation)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9Y294|rcsb pdb:1TEY|rcsb pdb:2I32|rcsb pdb:2IIJ|rcsb pdb:2IO5|rcsb pdb:3AAD|rcsb pdb:5C3I|rcsb pdb:6F0G|rcsb pdb:6F0H|rcsb pdb:6ZUF|reactome:R-HSA-2559584|rcsb pdb:6F0F refseq:NP_065723.1|refseq:XP_005245419.1|refseq:XP_016857364.1|ensembl:ENSG00000189334(gene)|ensembl:ENST00000344616(transcript)|ensembl:ENST00000368701(transcript)|ensembl:ENST00000368702(transcript)|ensembl:ENST00000476873(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0006915"(apoptotic process)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0042379"(chemokine receptor binding)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071624"(positive regulation of granulocyte chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028493|mint:Q9HCY8|rcsb pdb:2M0R - caution:This sequence has been withdrawn from Uniprot. comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:rIMptRSOYD+wfp0dMEHjhNNsHXQ9606 rogid:8XSIQKZSb+jAmTmawRUTHjcGwb49606 rigid:QRaYY4EbPeK4i/HGiVrIcubpvQo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y294 uniprotkb:P62805 intact:EBI-749553|uniprotkb:Q6IA08|uniprotkb:Q9P014|ensembl:ENSP00000229595 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:asf1a_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog A(gene name synonym)|uniprotkb:CCG1-interacting factor A(gene name synonym)|uniprotkb:ASF1A(gene name)|psi-mi:ASF1A(display_short)|uniprotkb:CGI-98(orf name)|uniprotkb:HSPC146(orf name) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476151|imex:IM-26985-145 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_054753.1|dip:DIP-29241N|ensembl:ENSG00000111875(gene)|ensembl:ENST00000229595(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0042692"(muscle cell differentiation)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9Y294|rcsb pdb:1TEY|rcsb pdb:2I32|rcsb pdb:2IIJ|rcsb pdb:2IO5|rcsb pdb:3AAD|rcsb pdb:5C3I|rcsb pdb:6F0G|rcsb pdb:6F0H|rcsb pdb:6ZUF|reactome:R-HSA-2559584|rcsb pdb:6F0F ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - caution:This sequence has been withdrawn from Uniprot. comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:rIMptRSOYD+wfp0dMEHjhNNsHXQ9606 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 rigid:QRaYY4EbPeK4i/HGiVrIcubpvQo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y294 uniprotkb:Q5UIP0 intact:EBI-749553|uniprotkb:Q6IA08|uniprotkb:Q9P014|ensembl:ENSP00000229595 intact:EBI-711331|uniprotkb:A6NC27|uniprotkb:C9JBR1|uniprotkb:Q5H9R3|uniprotkb:Q5UIP2|uniprotkb:Q66YK6|uniprotkb:Q6PRU2|uniprotkb:Q8TE94|uniprotkb:Q99772|uniprotkb:Q9H830|uniprotkb:Q9H9B9|uniprotkb:Q9NVP5|uniprotkb:Q9Y4R4|ensembl:ENSP00000243326|ensembl:ENSP00000390181 psi-mi:asf1a_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog A(gene name synonym)|uniprotkb:CCG1-interacting factor A(gene name synonym)|uniprotkb:ASF1A(gene name)|psi-mi:ASF1A(display_short)|uniprotkb:CGI-98(orf name)|uniprotkb:HSPC146(orf name) psi-mi:rif1_human(display_long)|uniprotkb:RIF1(gene name)|psi-mi:RIF1(display_short)|uniprotkb:Rap1-interacting factor 1 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476151|imex:IM-26985-145 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_054753.1|dip:DIP-29241N|ensembl:ENSG00000111875(gene)|ensembl:ENST00000229595(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0042692"(muscle cell differentiation)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9Y294|rcsb pdb:1TEY|rcsb pdb:2I32|rcsb pdb:2IIJ|rcsb pdb:2IO5|rcsb pdb:3AAD|rcsb pdb:5C3I|rcsb pdb:6F0G|rcsb pdb:6F0H|rcsb pdb:6ZUF|reactome:R-HSA-2559584|rcsb pdb:6F0F go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043247"(telomere maintenance in response to DNA damage)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0051233"(spindle midzone)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022031|interpro:IPR028566|mint:Q5UIP0|reactome:R-HSA-5693571|ensembl:ENSG00000080345(gene)|ensembl:ENST00000243326(transcript)|ensembl:ENST00000444746(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_001171134.1|refseq:NP_001171135.1|refseq:NP_001171136.1|refseq:NP_060621.3|refseq:XP_005246722.1 - caution:This sequence has been withdrawn from Uniprot. comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:rIMptRSOYD+wfp0dMEHjhNNsHXQ9606 rogid:XM3dyJZ0U4P2OUvgW3LOX2MLRDs9606 rigid:QRaYY4EbPeK4i/HGiVrIcubpvQo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y294 uniprotkb:Q01469 intact:EBI-749553|uniprotkb:Q6IA08|uniprotkb:Q9P014|ensembl:ENSP00000229595 intact:EBI-1054073|uniprotkb:B2R4K0|ensembl:ENSP00000297258 psi-mi:asf1a_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog A(gene name synonym)|uniprotkb:CCG1-interacting factor A(gene name synonym)|uniprotkb:ASF1A(gene name)|psi-mi:ASF1A(display_short)|uniprotkb:CGI-98(orf name)|uniprotkb:HSPC146(orf name) psi-mi:fabp5_human(display_long)|uniprotkb:Epidermal-type fatty acid-binding protein(gene name synonym)|uniprotkb:Psoriasis-associated fatty acid-binding protein homolog(gene name synonym)|uniprotkb:FABP5(gene name)|psi-mi:FABP5(display_short)|uniprotkb:Fatty acid-binding protein, epidermal(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476151|imex:IM-26985-145 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_054753.1|dip:DIP-29241N|ensembl:ENSG00000111875(gene)|ensembl:ENST00000229595(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0042692"(muscle cell differentiation)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9Y294|rcsb pdb:1TEY|rcsb pdb:2I32|rcsb pdb:2IIJ|rcsb pdb:2IO5|rcsb pdb:3AAD|rcsb pdb:5C3I|rcsb pdb:6F0G|rcsb pdb:6F0H|rcsb pdb:6ZUF|reactome:R-HSA-2559584|rcsb pdb:6F0F refseq:NP_001435.1|ensembl:ENSG00000164687(gene)|ensembl:ENST00000297258(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0008289"(lipid binding)|go:"GO:0008544"(epidermis development)|go:"GO:0010829"(negative regulation of glucose transmembrane transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031392"(regulation of prostaglandin biosynthetic process)|go:"GO:0035360"(positive regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099178"(regulation of retrograde trans-synaptic signaling by endocanabinoid)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990379"(lipid transport across blood-brain barrier)|interpro:IPR000463(Cytosolic fatty-acid binding)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR012674(Calycin)|interpro:IPR031259|mint:Q01469|rcsb pdb:1B56|rcsb pdb:1JJJ|rcsb pdb:4AZM|rcsb pdb:4AZR|rcsb pdb:4LKP|rcsb pdb:4LKT|rcsb pdb:5HZ5|rcsb pdb:5UR9|reactome:R-HSA-163560|reactome:R-HSA-5362517|reactome:R-HSA-6798695 - caution:This sequence has been withdrawn from Uniprot. comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:rIMptRSOYD+wfp0dMEHjhNNsHXQ9606 rogid:vxp81/mezHcm5oo27QOmAM8Y5dI9606 rigid:QRaYY4EbPeK4i/HGiVrIcubpvQo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y294 uniprotkb:P68431 intact:EBI-749553|uniprotkb:Q6IA08|uniprotkb:Q9P014|ensembl:ENSP00000229595 intact:EBI-79722|ensembl:ENSP00000352252|ensembl:ENSP00000358160|ensembl:ENSP00000366999|ensembl:ENSP00000480826|ensembl:ENSP00000482271|ensembl:ENSP00000483283|ensembl:ENSP00000484095|ensembl:ENSP00000484638|ensembl:ENSP00000484658|ensembl:ENSP00000484841|ensembl:ENSP00000489282|intact:EBI-1560041|uniprotkb:A0PJT7|uniprotkb:P02295|uniprotkb:P02296|uniprotkb:P16106|uniprotkb:Q6ISV8|uniprotkb:Q6NWP8|uniprotkb:Q6NWP9|uniprotkb:Q6NXU4|uniprotkb:Q71DJ3|uniprotkb:Q93081|uniprotkb:A5PLR1 psi-mi:asf1a_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog A(gene name synonym)|uniprotkb:CCG1-interacting factor A(gene name synonym)|uniprotkb:ASF1A(gene name)|psi-mi:ASF1A(display_short)|uniprotkb:CGI-98(orf name)|uniprotkb:HSPC146(orf name) psi-mi:h31_human(display_long)|uniprotkb:H3FA(gene name synonym)|uniprotkb:H3FL(gene name synonym)|uniprotkb:H3FD(gene name synonym)|uniprotkb:H3FI(gene name synonym)|uniprotkb:H3FH(gene name synonym)|uniprotkb:H3FK(gene name synonym)|uniprotkb:H3FF(gene name synonym)|uniprotkb:H3FJ(gene name synonym)|uniprotkb:H3FB(gene name synonym)|uniprotkb:Histone H3/a(gene name synonym)|uniprotkb:Histone H3/b(gene name synonym)|uniprotkb:Histone H3/c(gene name synonym)|uniprotkb:Histone H3/d(gene name synonym)|uniprotkb:Histone H3/f(gene name synonym)|uniprotkb:Histone H3/h(gene name synonym)|uniprotkb:Histone H3/i(gene name synonym)|uniprotkb:Histone H3/j(gene name synonym)|uniprotkb:Histone H3/k(gene name synonym)|uniprotkb:Histone H3/l(gene name synonym)|uniprotkb:H3C1(gene name)|psi-mi:H3C1(display_short)|uniprotkb:HIST1H3A(gene name synonym)|uniprotkb:H3C2(gene name)|psi-mi:H3C2(display_short)|uniprotkb:HIST1H3B(gene name synonym)|uniprotkb:H3C3(gene name)|psi-mi:H3C3(display_short)|uniprotkb:H3FC HIST1H3C(gene name synonym)|uniprotkb:H3C4(gene name)|psi-mi:H3C4(display_short)|uniprotkb:HIST1H3D(gene name synonym)|uniprotkb:H3C6(gene name)|psi-mi:H3C6(display_short)|uniprotkb:HIST1H3E(gene name synonym)|uniprotkb:H3C7(gene name)|psi-mi:H3C7(display_short)|uniprotkb:HIST1H3F(gene name synonym)|uniprotkb:H3C8(gene name)|psi-mi:H3C8(display_short)|uniprotkb:HIST1H3G(gene name synonym)|uniprotkb:H3C10(gene name)|psi-mi:H3C10(display_short)|uniprotkb:HIST1H3H(gene name synonym)|uniprotkb:H3C11(gene name)|psi-mi:H3C11(display_short)|uniprotkb:HIST1H3I(gene name synonym)|uniprotkb:H3C12(gene name)|psi-mi:H3C12(display_short)|uniprotkb:HIST1H3J(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476151|imex:IM-26985-145 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_054753.1|dip:DIP-29241N|ensembl:ENSG00000111875(gene)|ensembl:ENST00000229595(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0042692"(muscle cell differentiation)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9Y294|rcsb pdb:1TEY|rcsb pdb:2I32|rcsb pdb:2IIJ|rcsb pdb:2IO5|rcsb pdb:3AAD|rcsb pdb:5C3I|rcsb pdb:6F0G|rcsb pdb:6F0H|rcsb pdb:6ZUF|reactome:R-HSA-2559584|rcsb pdb:6F0F rcsb pdb:4TN7|rcsb pdb:4U68|rcsb pdb:4UP0|rcsb pdb:4UY4|rcsb pdb:4X3K|rcsb pdb:4Y6L|rcsb pdb:4YHP|rcsb pdb:4YHZ|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z0R|rcsb pdb:4Z2M|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:4QBS|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B31|rcsb pdb:5C11|rcsb pdb:5C13|rcsb pdb:5C3I|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5D6Y|rcsb pdb:5DAH|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5FFV|rcsb pdb:5GH9|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5H6Q|rcsb pdb:5H6R|rcsb pdb:5HJB|rcsb pdb:5HJC|rcsb pdb:5HJD|rcsb pdb:5HYN|rcsb pdb:5IQL|rcsb pdb:5J3V|rcsb pdb:5J9S|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5B2J|rcsb pdb:5JRG|rcsb pdb:5KJH|rcsb pdb:5KJI|rcsb pdb:5KKL|rcsb pdb:5LUG|rcsb pdb:5M5G|rcsb pdb:5MR8|rcsb pdb:5NNC|rcsb pdb:5OY3|rcsb pdb:5SVX|rcsb pdb:5SVY|rcsb pdb:5SZB|rcsb pdb:5SZC|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5T1G|rcsb pdb:5T1I|rcsb pdb:5T8R|rcsb pdb:5TBN|rcsb pdb:5TDR|rcsb pdb:5TDW|rcsb pdb:5U2J|rcsb pdb:5V21|rcsb pdb:5V22|rcsb pdb:5VA6|rcsb pdb:5VAB|rcsb pdb:5VGE|rcsb pdb:5VNB|rcsb pdb:5NND|rcsb pdb:5WLE|rcsb pdb:5WVO|rcsb pdb:5WXG|rcsb pdb:5WXH|rcsb pdb:5WYI|rcsb pdb:5X60|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5XFQ|rcsb pdb:5XFR|rcsb pdb:5XNV|rcsb pdb:5XTZ|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Y20|rcsb pdb:5Y2F|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:6AXJ|rcsb pdb:6AZE|rcsb pdb:6BHD|rcsb pdb:6BHE|rcsb pdb:6BHG|rcsb pdb:6BHH|rcsb pdb:6BHI|rcsb pdb:6D07|rcsb pdb:6D08|rcsb pdb:6E83|rcsb pdb:6E86|rcsb pdb:5WFC|rcsb pdb:6F6D|rcsb pdb:6HTS|rcsb pdb:6IEU|rcsb pdb:6IIS|rcsb pdb:6IIT|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6JXD|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6LS6|rcsb pdb:6LSD|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MIL|rcsb pdb:6MIM|rcsb pdb:6MIN|rcsb pdb:6MIO|rcsb pdb:6MIQ|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6HKT|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2H|rcsb pdb:6V2K|rcsb pdb:6V3N|rcsb pdb:6V41|rcsb pdb:6V92|rcsb pdb:6VIL|rcsb pdb:6WAV|rcsb pdb:6WW4|rcsb pdb:6YIF|rcsb pdb:6YIH|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:6R92|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7KLR|rcsb pdb:7LYC|reactome:R-HSA-1266695|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|ensembl:ENSG00000197153(gene)|ensembl:ENSG00000197409(gene)|ensembl:ENSG00000273983(gene)|ensembl:ENSG00000274750(gene)|ensembl:ENSG00000275379(gene)|ensembl:ENSG00000275714(gene)|ensembl:ENSG00000277775(gene)|ensembl:ENSG00000278828(gene)|ensembl:ENSG00000286522(gene)|ensembl:ENSG00000287080(gene)|ensembl:ENST00000356476(transcript)|ensembl:ENST00000359303(transcript)|ensembl:ENST00000369163(transcript)|ensembl:ENST00000612966(transcript)|ensembl:ENST00000613854(transcript)|ensembl:ENST00000614378(transcript)|ensembl:ENST00000614911(transcript)|ensembl:ENST00000616365(transcript)|ensembl:ENST00000618052(transcript)|ensembl:ENST00000621411(transcript)|ensembl:ENST00000634733(transcript)|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-3247509|reactome:R-HSA-9710421|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060968"(obsolete regulation of gene silencing)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|interpro:IPR009072(Histone-fold)|mint:P68431|rcsb pdb:1CS9|rcsb pdb:1CT6|rcsb pdb:1O9S|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|rcsb pdb:1Q3L|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|rcsb pdb:2B2T|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|rcsb pdb:2B2U|rcsb pdb:2B2V|rcsb pdb:2B2W|rcsb pdb:2C1J|rcsb pdb:2C1N|go:"GO:0016020"(membrane)|rcsb pdb:2CO0|rcsb pdb:2CV5|rcsb pdb:2FSA|rcsb pdb:2KWJ|rcsb pdb:2KWK|rcsb pdb:2L75|rcsb pdb:2LBM|rcsb pdb:2LGG|rcsb pdb:2M0O|reactome:R-HSA-983231|reactome:R-HSA-977225|rcsb pdb:2NDG|rcsb pdb:2OQ6|rcsb pdb:2OT7|rcsb pdb:2OX0|rcsb pdb:2RI7|rcsb pdb:2RR4|rcsb pdb:2UXN|rcsb pdb:2V85|rcsb pdb:2V89|rcsb pdb:2VNF|rcsb pdb:2VPG|rcsb pdb:2X0L|rcsb pdb:3A1B|rcsb pdb:2NDF|rcsb pdb:3AFA|rcsb pdb:3AVR|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3B95|rcsb pdb:3FDT|rcsb pdb:3KMT|rcsb pdb:3KQI|rcsb pdb:3LQI|rcsb pdb:3LQJ|rcsb pdb:3MP1|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O37|rcsb pdb:3QJ6|rcsb pdb:3RIG|rcsb pdb:3RIY|rcsb pdb:3SOU|rcsb pdb:3SOW|rcsb pdb:3U31|rcsb pdb:3U3D|rcsb pdb:3U4S|rcsb pdb:3U5N|rcsb pdb:3U5O|rcsb pdb:3AZK|rcsb pdb:3U5P|rcsb pdb:3UEE|rcsb pdb:3UEF|rcsb pdb:3UII|rcsb pdb:3UIK|rcsb pdb:3V43|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:3ZG6|rcsb pdb:3ZVY|rcsb pdb:4A0J|rcsb pdb:4A0N|rcsb pdb:4A7J|rcsb pdb:3UIG|rcsb pdb:4BD3|rcsb pdb:4C1Q|rcsb pdb:4F4U|rcsb pdb:4F56|rcsb pdb:4FWF|rcsb pdb:4HON|rcsb pdb:4I51|rcsb pdb:4L7X|rcsb pdb:4LK9|rcsb pdb:4LKA|rcsb pdb:4LLB|rcsb pdb:4LXL|rcsb pdb:4N4H|rcsb pdb:4QBQ|rcsb pdb:4QBR|refseq:NP_003520.1|refseq:NP_003521.2|refseq:NP_003522.1|refseq:NP_003523.1|refseq:NP_003524.1|refseq:NP_003525.1|refseq:NP_003526.1|refseq:NP_003527.1|refseq:NP_003528.1|refseq:NP_066298.1|dip:DIP-29371N - caution:This sequence has been withdrawn from Uniprot. comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:rIMptRSOYD+wfp0dMEHjhNNsHXQ9606 rogid:ood0OohxZHuhsWZtO7U7GMc+LwM9606 rigid:QRaYY4EbPeK4i/HGiVrIcubpvQo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y294 uniprotkb:P22528 intact:EBI-749553|uniprotkb:Q6IA08|uniprotkb:Q9P014|ensembl:ENSP00000229595 intact:EBI-1058892|ensembl:ENSP00000306461|uniprotkb:B2R5H7|uniprotkb:P22529|uniprotkb:P22530|uniprotkb:Q5T524 psi-mi:asf1a_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog A(gene name synonym)|uniprotkb:CCG1-interacting factor A(gene name synonym)|uniprotkb:ASF1A(gene name)|psi-mi:ASF1A(display_short)|uniprotkb:CGI-98(orf name)|uniprotkb:HSPC146(orf name) psi-mi:spr1b_human(display_long)|uniprotkb:SPRR1B(gene name)|psi-mi:SPRR1B(display_short)|uniprotkb:Small proline-rich protein IB(gene name synonym)|uniprotkb:14.9 kDa pancornulin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476151|imex:IM-26985-145 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_054753.1|dip:DIP-29241N|ensembl:ENSG00000111875(gene)|ensembl:ENST00000229595(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0042692"(muscle cell differentiation)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9Y294|rcsb pdb:1TEY|rcsb pdb:2I32|rcsb pdb:2IIJ|rcsb pdb:2IO5|rcsb pdb:3AAD|rcsb pdb:5C3I|rcsb pdb:6F0G|rcsb pdb:6F0H|rcsb pdb:6ZUF|reactome:R-HSA-2559584|rcsb pdb:6F0F ensembl:ENSG00000169469(gene)|ensembl:ENST00000307098(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0031424"(keratinization)|interpro:IPR003302("Cornifin (SPRR)")|mint:P22528|reactome:R-HSA-6809371|refseq:NP_003116.2 - caution:This sequence has been withdrawn from Uniprot. comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:rIMptRSOYD+wfp0dMEHjhNNsHXQ9606 rogid:WU0vu+DHdIJm0x40HdcpAdJgdgo9606 rigid:QRaYY4EbPeK4i/HGiVrIcubpvQo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y294 uniprotkb:Q16576 intact:EBI-749553|uniprotkb:Q6IA08|uniprotkb:Q9P014|ensembl:ENSP00000229595 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 psi-mi:asf1a_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog A(gene name synonym)|uniprotkb:CCG1-interacting factor A(gene name synonym)|uniprotkb:ASF1A(gene name)|psi-mi:ASF1A(display_short)|uniprotkb:CGI-98(orf name)|uniprotkb:HSPC146(orf name) psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476151|imex:IM-26985-145 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_054753.1|dip:DIP-29241N|ensembl:ENSG00000111875(gene)|ensembl:ENST00000229595(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0042692"(muscle cell differentiation)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9Y294|rcsb pdb:1TEY|rcsb pdb:2I32|rcsb pdb:2IIJ|rcsb pdb:2IO5|rcsb pdb:3AAD|rcsb pdb:5C3I|rcsb pdb:6F0G|rcsb pdb:6F0H|rcsb pdb:6ZUF|reactome:R-HSA-2559584|rcsb pdb:6F0F refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N - caution:This sequence has been withdrawn from Uniprot. comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:rIMptRSOYD+wfp0dMEHjhNNsHXQ9606 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rigid:QRaYY4EbPeK4i/HGiVrIcubpvQo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y294 uniprotkb:Q9NZT1 intact:EBI-749553|uniprotkb:Q6IA08|uniprotkb:Q9P014|ensembl:ENSP00000229595 intact:EBI-1051681|uniprotkb:Q8IXU8|uniprotkb:Q5SQI3|ensembl:ENSP00000369689 psi-mi:asf1a_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog A(gene name synonym)|uniprotkb:CCG1-interacting factor A(gene name synonym)|uniprotkb:ASF1A(gene name)|psi-mi:ASF1A(display_short)|uniprotkb:CGI-98(orf name)|uniprotkb:HSPC146(orf name) psi-mi:call5_human(display_long)|uniprotkb:Calmodulin-like skin protein(gene name synonym)|uniprotkb:CALML5(gene name)|psi-mi:CALML5(display_short)|uniprotkb:CLSP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476151|imex:IM-26985-145 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_054753.1|dip:DIP-29241N|ensembl:ENSG00000111875(gene)|ensembl:ENST00000229595(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0042692"(muscle cell differentiation)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9Y294|rcsb pdb:1TEY|rcsb pdb:2I32|rcsb pdb:2IIJ|rcsb pdb:2IO5|rcsb pdb:3AAD|rcsb pdb:5C3I|rcsb pdb:6F0G|rcsb pdb:6F0H|rcsb pdb:6ZUF|reactome:R-HSA-2559584|rcsb pdb:6F0F refseq:NP_059118.2|ensembl:ENST00000380332(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007165"(signal transduction)|go:"GO:0008544"(epidermis development)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q9NZT1|rcsb pdb:2B1U|reactome:R-HSA-6798695|ensembl:ENSG00000178372(gene) - caution:This sequence has been withdrawn from Uniprot. comment:"author score: 31" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:rIMptRSOYD+wfp0dMEHjhNNsHXQ9606 rogid:uPD/avsoqpiogqHCK5TGJQwvCX89606 rigid:QRaYY4EbPeK4i/HGiVrIcubpvQo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y294 uniprotkb:P01040 intact:EBI-749553|uniprotkb:Q6IA08|uniprotkb:Q9P014|ensembl:ENSP00000229595 intact:EBI-724303|ensembl:ENSP00000264474|uniprotkb:Q6IB90 psi-mi:asf1a_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog A(gene name synonym)|uniprotkb:CCG1-interacting factor A(gene name synonym)|uniprotkb:ASF1A(gene name)|psi-mi:ASF1A(display_short)|uniprotkb:CGI-98(orf name)|uniprotkb:HSPC146(orf name) psi-mi:cyta_human(display_long)|uniprotkb:Cystatin-AS(gene name synonym)|uniprotkb:Stefin-A(gene name synonym)|uniprotkb:CSTA(gene name)|psi-mi:CSTA(display_short)|uniprotkb:STF1(gene name synonym)|uniprotkb:STFA(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476151|imex:IM-26985-145 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_054753.1|dip:DIP-29241N|ensembl:ENSG00000111875(gene)|ensembl:ENST00000229595(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0042692"(muscle cell differentiation)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9Y294|rcsb pdb:1TEY|rcsb pdb:2I32|rcsb pdb:2IIJ|rcsb pdb:2IO5|rcsb pdb:3AAD|rcsb pdb:5C3I|rcsb pdb:6F0G|rcsb pdb:6F0H|rcsb pdb:6ZUF|reactome:R-HSA-2559584|rcsb pdb:6F0F refseq:NP_005204.1|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR001713(Proteinase inhibitor I25A, stefin A)|mint:P01040|rcsb pdb:1CYU|rcsb pdb:1CYV|rcsb pdb:1DVC|rcsb pdb:1DVD|rcsb pdb:1GD3|rcsb pdb:1GD4|rcsb pdb:1N9J|rcsb pdb:1NB3|rcsb pdb:1NB5|rcsb pdb:3K9M|rcsb pdb:3KFQ|interpro:IPR018073|rcsb pdb:3KSE|reactome:R-HSA-6809371|ensembl:ENSG00000121552(gene)|ensembl:ENST00000264474(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002020"(protease binding)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0045861"(negative regulation of proteolysis) - caution:This sequence has been withdrawn from Uniprot. comment:"author score: 38" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:rIMptRSOYD+wfp0dMEHjhNNsHXQ9606 rogid:SzbpyWUHlOtItIvffzuwhcqFsDI9606 rigid:QRaYY4EbPeK4i/HGiVrIcubpvQo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y294 uniprotkb:Q9NVP2 intact:EBI-749553|uniprotkb:Q6IA08|uniprotkb:Q9P014|ensembl:ENSP00000229595 intact:EBI-1055650|uniprotkb:Q53G51|uniprotkb:Q9NVZ0|ensembl:ENSP00000263382|ensembl:ENSP00000499863 psi-mi:asf1a_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog A(gene name synonym)|uniprotkb:CCG1-interacting factor A(gene name synonym)|uniprotkb:ASF1A(gene name)|psi-mi:ASF1A(display_short)|uniprotkb:CGI-98(orf name)|uniprotkb:HSPC146(orf name) psi-mi:asf1b_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog B(gene name synonym)|uniprotkb:CCG1-interacting factor A-II(gene name synonym)|uniprotkb:ASF1B(gene name)|psi-mi:ASF1B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476151|imex:IM-26985-145 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_054753.1|dip:DIP-29241N|ensembl:ENSG00000111875(gene)|ensembl:ENST00000229595(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0042692"(muscle cell differentiation)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9Y294|rcsb pdb:1TEY|rcsb pdb:2I32|rcsb pdb:2IIJ|rcsb pdb:2IO5|rcsb pdb:3AAD|rcsb pdb:5C3I|rcsb pdb:6F0G|rcsb pdb:6F0H|rcsb pdb:6ZUF|reactome:R-HSA-2559584|rcsb pdb:6F0F refseq:NP_060624.1|ensembl:ENSG00000105011(gene)|ensembl:ENSG00000288210(gene)|ensembl:ENST00000263382(transcript)|ensembl:ENST00000672225(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9NVP2|rcsb pdb:5BNX|rcsb pdb:5BO0|dip:DIP-29242N - caution:This sequence has been withdrawn from Uniprot. caution:This sequence has been withdrawn from Uniprot.|comment:"author score: 42" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:rIMptRSOYD+wfp0dMEHjhNNsHXQ9606 rogid:gG2Px6QOw95EohRaaWivH7GrSr09606 rigid:QRaYY4EbPeK4i/HGiVrIcubpvQo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y294 uniprotkb:Q9NPG3 intact:EBI-749553|uniprotkb:Q6IA08|uniprotkb:Q9P014|ensembl:ENSP00000229595 intact:EBI-2880187|ensembl:ENSP00000262376|ensembl:ENSP00000379894|uniprotkb:B7Z6D3|uniprotkb:Q13079|uniprotkb:Q9P1P7|uniprotkb:D3DUE8 psi-mi:asf1a_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog A(gene name synonym)|uniprotkb:CCG1-interacting factor A(gene name synonym)|uniprotkb:ASF1A(gene name)|psi-mi:ASF1A(display_short)|uniprotkb:CGI-98(orf name)|uniprotkb:HSPC146(orf name) psi-mi:ubn1_human(display_long)|uniprotkb:UBN1(gene name)|psi-mi:UBN1(display_short)|uniprotkb:HIRA-binding protein(gene name synonym)|uniprotkb:Protein VT4(gene name synonym)|uniprotkb:Ubiquitously expressed nuclear protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476151|imex:IM-26985-145 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_054753.1|dip:DIP-29241N|ensembl:ENSG00000111875(gene)|ensembl:ENST00000229595(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0042692"(muscle cell differentiation)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9Y294|rcsb pdb:1TEY|rcsb pdb:2I32|rcsb pdb:2IIJ|rcsb pdb:2IO5|rcsb pdb:3AAD|rcsb pdb:5C3I|rcsb pdb:6F0G|rcsb pdb:6F0H|rcsb pdb:6ZUF|reactome:R-HSA-2559584|rcsb pdb:6F0F ensembl:ENSG00000118900(gene)|ensembl:ENST00000262376(transcript)|ensembl:ENST00000396658(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0034451"(centriolar satellite)|interpro:IPR014840("Histone promoter control 2 (HPC2)")|interpro:IPR026936|interpro:IPR026947|mint:Q9NPG3|rcsb pdb:4ZBJ|reactome:R-HSA-2559584|go:"GO:0005654"(nucleoplasm)|refseq:NP_001072982.1|refseq:XP_016878678.1|refseq:NP_001275585.1|ensembl:ENSP00000262376|ensembl:ENSP00000379894|ensembl:ENST00000590769|ensembl:ENSP00000468740 - caution:This sequence has been withdrawn from Uniprot. comment:"author score: 44" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:rIMptRSOYD+wfp0dMEHjhNNsHXQ9606 rogid:IT0lTmzNcbWFQVVD5DfATSqxjwg9606 rigid:QRaYY4EbPeK4i/HGiVrIcubpvQo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y294 uniprotkb:Q9Y6J0 intact:EBI-749553|uniprotkb:Q6IA08|uniprotkb:Q9P014|ensembl:ENSP00000229595 intact:EBI-2795712|uniprotkb:Q9Y460|uniprotkb:G5E9F3|uniprotkb:Q6PHY0|intact:EBI-28988204|ensembl:ENSP00000263119|ensembl:ENSP00000381364 psi-mi:asf1a_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog A(gene name synonym)|uniprotkb:CCG1-interacting factor A(gene name synonym)|uniprotkb:ASF1A(gene name)|psi-mi:ASF1A(display_short)|uniprotkb:CGI-98(orf name)|uniprotkb:HSPC146(orf name) psi-mi:cabin_human(display_long)|uniprotkb:CABIN1(gene name)|psi-mi:CABIN1(display_short)|uniprotkb:KIAA0330(gene name synonym)|uniprotkb:Calcineurin inhibitor(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476151|imex:IM-26985-145 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_054753.1|dip:DIP-29241N|ensembl:ENSG00000111875(gene)|ensembl:ENST00000229595(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0042692"(muscle cell differentiation)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9Y294|rcsb pdb:1TEY|rcsb pdb:2I32|rcsb pdb:2IIJ|rcsb pdb:2IO5|rcsb pdb:3AAD|rcsb pdb:5C3I|rcsb pdb:6F0G|rcsb pdb:6F0H|rcsb pdb:6ZUF|reactome:R-HSA-2559584|rcsb pdb:6F0F refseq:NP_001186210.1|refseq:NP_001188358.1|refseq:NP_036427.1|refseq:XP_016884172.1|ensembl:ENSP00000263119|ensembl:ENSP00000381364|ensembl:ENST00000405822|ensembl:ENSP00000384694|ensembl:ENSG00000099991(gene)|ensembl:ENST00000263119(transcript)|ensembl:ENST00000398319(transcript)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016235"(aggresome)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015134(MEF2 binding)|interpro:IPR019734|interpro:IPR033053|mint:Q9Y6J0|rcsb pdb:1N6J|reactome:R-HSA-2559584 - caution:This sequence has been withdrawn from Uniprot. comment:"author score: 44" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:rIMptRSOYD+wfp0dMEHjhNNsHXQ9606 rogid:b4BLYv/aw7zl2SZQXLXAQr+RmY49606 rigid:QRaYY4EbPeK4i/HGiVrIcubpvQo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y294 uniprotkb:Q86UE8 intact:EBI-749553|uniprotkb:Q6IA08|uniprotkb:Q9P014|ensembl:ENSP00000229595 intact:EBI-1047967|uniprotkb:Q9UKI7|uniprotkb:Q9Y4F7|uniprotkb:D3DU07|intact:EBI-28969484|ensembl:ENSP00000316512 psi-mi:asf1a_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog A(gene name synonym)|uniprotkb:CCG1-interacting factor A(gene name synonym)|uniprotkb:ASF1A(gene name)|psi-mi:ASF1A(display_short)|uniprotkb:CGI-98(orf name)|uniprotkb:HSPC146(orf name) psi-mi:tlk2_human(display_long)|uniprotkb:Tousled-like kinase 2(gene name synonym)|uniprotkb:PKU-alpha(gene name synonym)|uniprotkb:TLK2(gene name)|psi-mi:TLK2(display_short)|uniprotkb:HsHPK(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476151|imex:IM-26985-145 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_054753.1|dip:DIP-29241N|ensembl:ENSG00000111875(gene)|ensembl:ENST00000229595(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0042692"(muscle cell differentiation)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9Y294|rcsb pdb:1TEY|rcsb pdb:2I32|rcsb pdb:2IIJ|rcsb pdb:2IO5|rcsb pdb:3AAD|rcsb pdb:5C3I|rcsb pdb:6F0G|rcsb pdb:6F0H|rcsb pdb:6ZUF|reactome:R-HSA-2559584|rcsb pdb:6F0F refseq:NP_006843.2|refseq:NP_001271262.1|ensembl:ENSP00000316512|ensembl:ENST00000343388|ensembl:ENSP00000340800|ensembl:ENST00000346027|ensembl:ENSP00000275780|ensembl:ENST00000682085|ensembl:ENSP00000506744|ensembl:ENST00000683104|ensembl:ENSP00000508242|refseq:XP_011522518.1|refseq:XP_011522519.1|refseq:XP_011522524.1|ensembl:ENSG00000146872(gene)|ensembl:ENST00000326270(transcript)|go:"GO:0001672"(regulation of chromatin assembly or disassembly)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005882"(intermediate filament)|go:"GO:0006325"(chromatin organization)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR027086|mint:Q86UE8|rcsb pdb:5O0Y|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|refseq:XP_016879533.1|refseq:XP_016879535.1|refseq:XP_016879536.1|refseq:XP_016879540.1|refseq:XP_016879541.1|refseq:XP_016879542.1|refseq:NP_001271292.1 - caution:This sequence has been withdrawn from Uniprot. comment:"author score: 49" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:rIMptRSOYD+wfp0dMEHjhNNsHXQ9606 rogid:K1u8NeS9j5URs6/bUJn47WPk5Ss9606 rigid:QRaYY4EbPeK4i/HGiVrIcubpvQo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y294 uniprotkb:Q6ZU65 intact:EBI-749553|uniprotkb:Q6IA08|uniprotkb:Q9P014|ensembl:ENSP00000229595 intact:EBI-9661773|uniprotkb:A4D1S2|uniprotkb:Q2YDY4|uniprotkb:Q6P1K0|uniprotkb:Q86XN9|uniprotkb:Q8N7D1|ensembl:ENSP00000418648 psi-mi:asf1a_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog A(gene name synonym)|uniprotkb:CCG1-interacting factor A(gene name synonym)|uniprotkb:ASF1A(gene name)|psi-mi:ASF1A(display_short)|uniprotkb:CGI-98(orf name)|uniprotkb:HSPC146(orf name) psi-mi:ubn2_human(display_long)|uniprotkb:UBN2(gene name)|psi-mi:UBN2(display_short)|uniprotkb:KIAA2030(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476151|imex:IM-26985-145 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_054753.1|dip:DIP-29241N|ensembl:ENSG00000111875(gene)|ensembl:ENST00000229595(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0042692"(muscle cell differentiation)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9Y294|rcsb pdb:1TEY|rcsb pdb:2I32|rcsb pdb:2IIJ|rcsb pdb:2IO5|rcsb pdb:3AAD|rcsb pdb:5C3I|rcsb pdb:6F0G|rcsb pdb:6F0H|rcsb pdb:6ZUF|reactome:R-HSA-2559584|rcsb pdb:6F0F ensembl:ENSP00000418648|refseq:NP_775840.3|dip:DIP-47312N|ensembl:ENSG00000157741(gene)|ensembl:ENST00000473989(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|interpro:IPR014840("Histone promoter control 2 (HPC2)")|interpro:IPR026943|interpro:IPR026947|mint:Q6ZU65 - caution:This sequence has been withdrawn from Uniprot. comment:"author score: 49" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:rIMptRSOYD+wfp0dMEHjhNNsHXQ9606 rogid:Z45kNtHT1rLdgqkCTrcRGD7L2749606 rigid:QRaYY4EbPeK4i/HGiVrIcubpvQo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y294 uniprotkb:O14929 intact:EBI-749553|uniprotkb:Q6IA08|uniprotkb:Q9P014|ensembl:ENSP00000229595 intact:EBI-2339359|uniprotkb:Q53SU4|uniprotkb:Q53QF0|uniprotkb:Q49A44|uniprotkb:Q6P594|uniprotkb:Q8WWB9|ensembl:ENSP00000264108 psi-mi:asf1a_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog A(gene name synonym)|uniprotkb:CCG1-interacting factor A(gene name synonym)|uniprotkb:ASF1A(gene name)|psi-mi:ASF1A(display_short)|uniprotkb:CGI-98(orf name)|uniprotkb:HSPC146(orf name) psi-mi:hat1_human(display_long)|uniprotkb:HAT1(gene name)|psi-mi:HAT1(display_short)|uniprotkb:KAT1(gene name synonym)|uniprotkb:Histone acetyltransferase 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476151|imex:IM-26985-145 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_054753.1|dip:DIP-29241N|ensembl:ENSG00000111875(gene)|ensembl:ENST00000229595(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0042692"(muscle cell differentiation)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9Y294|rcsb pdb:1TEY|rcsb pdb:2I32|rcsb pdb:2IIJ|rcsb pdb:2IO5|rcsb pdb:3AAD|rcsb pdb:5C3I|rcsb pdb:6F0G|rcsb pdb:6F0H|rcsb pdb:6ZUF|reactome:R-HSA-2559584|rcsb pdb:6F0F refseq:NP_003633.1|dip:DIP-52811N|ensembl:ENSG00000128708(gene)|ensembl:ENST00000264108(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006323"(DNA packaging)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006348"|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0007584"(response to nutrient)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR013523(Histone acetyltransferase HAT1, C-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017380(Histone acetyltransferase type B, catalytic subunit)|interpro:IPR019467|interpro:IPR037113|mint:O14929|rcsb pdb:2P0W|rcsb pdb:6VO5|reactome:R-HSA-3214847 - caution:This sequence has been withdrawn from Uniprot. comment:"author score: 66" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:rIMptRSOYD+wfp0dMEHjhNNsHXQ9606 rogid:80KgRaid3NeRfAUdTHMQ/r0VuGo9606 rigid:QRaYY4EbPeK4i/HGiVrIcubpvQo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y294 uniprotkb:P54198 intact:EBI-749553|uniprotkb:Q6IA08|uniprotkb:Q9P014|ensembl:ENSP00000229595 intact:EBI-372342|uniprotkb:Q05BU9|uniprotkb:Q8IXN2|ensembl:ENSP00000263208 psi-mi:asf1a_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog A(gene name synonym)|uniprotkb:CCG1-interacting factor A(gene name synonym)|uniprotkb:ASF1A(gene name)|psi-mi:ASF1A(display_short)|uniprotkb:CGI-98(orf name)|uniprotkb:HSPC146(orf name) psi-mi:hira_human(display_long)|uniprotkb:HIRA(gene name)|psi-mi:HIRA(display_short)|uniprotkb:TUP1-like enhancer of split protein 1(gene name synonym)|uniprotkb:DGCR1(gene name synonym)|uniprotkb:HIR(gene name synonym)|uniprotkb:TUPLE1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476151|imex:IM-26985-145 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_054753.1|dip:DIP-29241N|ensembl:ENSG00000111875(gene)|ensembl:ENST00000229595(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0042692"(muscle cell differentiation)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9Y294|rcsb pdb:1TEY|rcsb pdb:2I32|rcsb pdb:2IIJ|rcsb pdb:2IO5|rcsb pdb:3AAD|rcsb pdb:5C3I|rcsb pdb:6F0G|rcsb pdb:6F0H|rcsb pdb:6ZUF|reactome:R-HSA-2559584|rcsb pdb:6F0F refseq:NP_003316.3|dip:DIP-29240N|ensembl:ENSG00000100084(gene)|ensembl:ENST00000263208(transcript)|go:"GO:0000417"(HIR complex)|go:"GO:0000785"(chromatin)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0016605"(PML body)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR011494(TUP1-like enhancer of split)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031120|interpro:IPR036322|mint:P54198|rcsb pdb:2I32|rcsb pdb:5YJE|reactome:R-HSA-2559584 - caution:This sequence has been withdrawn from Uniprot. comment:"author score: 70" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:rIMptRSOYD+wfp0dMEHjhNNsHXQ9606 rogid:en6l6z4CNWhF4Wlj5ou4DDTfETg9606 rigid:QRaYY4EbPeK4i/HGiVrIcubpvQo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y294 uniprotkb:P49321 intact:EBI-749553|uniprotkb:Q6IA08|uniprotkb:Q9P014|ensembl:ENSP00000229595 intact:EBI-716205|uniprotkb:Q53GW5|uniprotkb:Q5T625|uniprotkb:Q5T622|uniprotkb:Q96A69|uniprotkb:Q9BTW2|uniprotkb:A8K6H2|uniprotkb:B4DQP3|uniprotkb:F5H3J2|uniprotkb:D3DQ07|intact:EBI-28989159|ensembl:ENSP00000255120 psi-mi:asf1a_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog A(gene name synonym)|uniprotkb:CCG1-interacting factor A(gene name synonym)|uniprotkb:ASF1A(gene name)|psi-mi:ASF1A(display_short)|uniprotkb:CGI-98(orf name)|uniprotkb:HSPC146(orf name) psi-mi:nasp_human(display_long)|uniprotkb:NASP(gene name)|psi-mi:NASP(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476151|imex:IM-26985-145 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_054753.1|dip:DIP-29241N|ensembl:ENSG00000111875(gene)|ensembl:ENST00000229595(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0042692"(muscle cell differentiation)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9Y294|rcsb pdb:1TEY|rcsb pdb:2I32|rcsb pdb:2IIJ|rcsb pdb:2IO5|rcsb pdb:3AAD|rcsb pdb:5C3I|rcsb pdb:6F0G|rcsb pdb:6F0H|rcsb pdb:6ZUF|reactome:R-HSA-2559584|rcsb pdb:6F0F refseq:NP_001182122.1|refseq:NP_002473.2|refseq:NP_689511.2|ensembl:ENSG00000132780(gene)|ensembl:ENST00000350030(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0001824"(blastocyst development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0008584"(male gonad development)|go:"GO:0015031"(protein transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033574"(response to testosterone)|go:"GO:0034080"(CENP-A containing chromatin assembly)|go:"GO:0042393"(histone binding)|go:"GO:0043486"(histone exchange)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019544|interpro:IPR019734|mint:P49321|ensembl:ENSP00000255120|ensembl:ENST00000351223|ensembl:ENSP00000255121|ensembl:ENST00000537798|ensembl:ENSP00000438871|refseq:XP_005270945.1|dip:DIP-47269N - caution:This sequence has been withdrawn from Uniprot. comment:"author score: 71" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:rIMptRSOYD+wfp0dMEHjhNNsHXQ9606 rogid:8BOknyp+vOh6NF+fXZPYbbqFbH49606 rigid:QRaYY4EbPeK4i/HGiVrIcubpvQo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y294 uniprotkb:Q8IWY9 intact:EBI-749553|uniprotkb:Q6IA08|uniprotkb:Q9P014|ensembl:ENSP00000229595 intact:EBI-726307|uniprotkb:Q6NYD0|uniprotkb:Q7Z7L5|uniprotkb:Q969N3|ensembl:ENSP00000348564 psi-mi:asf1a_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog A(gene name synonym)|uniprotkb:CCG1-interacting factor A(gene name synonym)|uniprotkb:ASF1A(gene name)|psi-mi:ASF1A(display_short)|uniprotkb:CGI-98(orf name)|uniprotkb:HSPC146(orf name) psi-mi:cdan1_human(display_long)|uniprotkb:CDAN1(gene name)|psi-mi:CDAN1(display_short)|uniprotkb:UNQ664/PRO1295(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476151|imex:IM-26985-145 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_054753.1|dip:DIP-29241N|ensembl:ENSG00000111875(gene)|ensembl:ENST00000229595(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0042692"(muscle cell differentiation)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9Y294|rcsb pdb:1TEY|rcsb pdb:2I32|rcsb pdb:2IIJ|rcsb pdb:2IO5|rcsb pdb:3AAD|rcsb pdb:5C3I|rcsb pdb:6F0G|rcsb pdb:6F0H|rcsb pdb:6ZUF|reactome:R-HSA-2559584|rcsb pdb:6F0F refseq:NP_612486.2|dip:DIP-24225N|ensembl:ENSG00000140326(gene)|ensembl:ENST00000356231(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0008104"(protein localization)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031497"(chromatin assembly)|interpro:IPR028171|interpro:IPR040031|mint:Q8IWY9 - caution:This sequence has been withdrawn from Uniprot. comment:"author score: 94" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:rIMptRSOYD+wfp0dMEHjhNNsHXQ9606 rogid:Hbm36aMIq0BwSxCOLnxRl3vyYZY9606 rigid:QRaYY4EbPeK4i/HGiVrIcubpvQo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y294 uniprotkb:Q9Y2V0 intact:EBI-749553|uniprotkb:Q6IA08|uniprotkb:Q9P014|ensembl:ENSP00000229595 intact:EBI-1047601|uniprotkb:B2RD87|ensembl:ENSP00000401362|ensembl:ENSP00000455397 psi-mi:asf1a_human(display_long)|uniprotkb:Anti-silencing function protein 1 homolog A(gene name synonym)|uniprotkb:CCG1-interacting factor A(gene name synonym)|uniprotkb:ASF1A(gene name)|psi-mi:ASF1A(display_short)|uniprotkb:CGI-98(orf name)|uniprotkb:HSPC146(orf name) psi-mi:cdin1_human(display_long)|uniprotkb:CDIN1(gene name)|psi-mi:CDIN1(display_short)|uniprotkb:C15orf41(gene name synonym)|uniprotkb:Protein HH114(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476151|imex:IM-26985-145 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_054753.1|dip:DIP-29241N|ensembl:ENSG00000111875(gene)|ensembl:ENST00000229595(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0042692"(muscle cell differentiation)|interpro:IPR006818(Anti-silencing protein, ASF1-like)|interpro:IPR036747|mint:Q9Y294|rcsb pdb:1TEY|rcsb pdb:2I32|rcsb pdb:2IIJ|rcsb pdb:2IO5|rcsb pdb:3AAD|rcsb pdb:5C3I|rcsb pdb:6F0G|rcsb pdb:6F0H|rcsb pdb:6ZUF|reactome:R-HSA-2559584|rcsb pdb:6F0F refseq:NP_001123482.1|refseq:NP_115888.1|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030218"(erythrocyte differentiation)|interpro:IPR029404|mint:Q9Y2V0|ensembl:ENSG00000186073(gene)|ensembl:ENST00000437989(transcript)|ensembl:ENST00000566621(transcript)|refseq:NP_001308685.1|refseq:NP_001308688.1|refseq:NP_001277161.1|refseq:NP_001277162.1 - caution:This sequence has been withdrawn from Uniprot. comment:"author score: 116" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:rIMptRSOYD+wfp0dMEHjhNNsHXQ9606 rogid:trhVL88F7JR6DmfrMmxMgvzsX6c9606 rigid:QRaYY4EbPeK4i/HGiVrIcubpvQo false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UBL3 uniprotkb:Q8NFC6 intact:EBI-540797|uniprotkb:O60659|uniprotkb:O60660|uniprotkb:Q96B62|ensembl:ENSP00000340896|uniprotkb:A8K7C3|uniprotkb:D3DSW9 intact:EBI-2654318|uniprotkb:Q9NTD6|uniprotkb:Q96AL1|uniprotkb:Q9H6G0|uniprotkb:Q6P0M8|uniprotkb:Q9P2L9|ensembl:ENSP00000040738 psi-mi:ash2l_human(display_long)|uniprotkb:ASH2-like protein(gene name synonym)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym) psi-mi:bd1l1_human(display_long)|uniprotkb:BOD1L1(gene name)|psi-mi:BOD1L1(display_short)|uniprotkb:BOD1L(gene name synonym)|uniprotkb:FAM44A(gene name synonym)|uniprotkb:KIAA1327(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476274|imex:IM-26985-527 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001098684.1|refseq:NP_004665.2|ensembl:ENSG00000129691(gene)|ensembl:ENST00000343823(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|mint:Q9UBL3|rcsb pdb:3RSN|rcsb pdb:3S32|rcsb pdb:3TOJ|rcsb pdb:4RIQ|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6E2H|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|rcsb pdb:4X8N|refseq:NP_001248761.1|dip:DIP-29222N refseq:NP_683692.2|ensembl:ENSG00000038219(gene)|ensembl:ENST00000040738(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR043244|mint:Q8NFC6 - - comment:"author score: 27" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZUYI3M78nGeeb8K2eIiDSw1uWeo9606 rogid:/sFfw7CP8rOZG3hZNsT0npwIZIQ9606 rigid:d7MNx4LvTBfadpFsgKxFZJi2uok false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UBL3 uniprotkb:Q9UPS6 intact:EBI-540797|uniprotkb:O60659|uniprotkb:O60660|uniprotkb:Q96B62|ensembl:ENSP00000340896|uniprotkb:A8K7C3|uniprotkb:D3DSW9 intact:EBI-8836493|uniprotkb:F6MFW1|ensembl:ENSP00000474253|ensembl:ENSP00000481531 psi-mi:ash2l_human(display_long)|uniprotkb:ASH2-like protein(gene name synonym)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym) psi-mi:set1b_human(display_long)|uniprotkb:KIAA1076(gene name synonym)|uniprotkb:KMT2G(gene name synonym)|uniprotkb:Lysine N-methyltransferase 2G(gene name synonym)|uniprotkb:SET domain-containing protein 1B(gene name synonym)|uniprotkb:SET1B(gene name synonym)|uniprotkb:SETD1B(gene name)|psi-mi:SETD1B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476274|imex:IM-26985-527 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001098684.1|refseq:NP_004665.2|ensembl:ENSG00000129691(gene)|ensembl:ENST00000343823(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|mint:Q9UBL3|rcsb pdb:3RSN|rcsb pdb:3S32|rcsb pdb:3TOJ|rcsb pdb:4RIQ|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6E2H|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|rcsb pdb:4X8N|refseq:NP_001248761.1|dip:DIP-29222N refseq:NP_055863.1|ensembl:ENST00000542440|ensembl:ENSP00000442924|ensembl:ENSP00000474253|ensembl:ENSP00000481531|refseq:XP_005253915.1|refseq:XP_006719359.1|dip:DIP-61947N|go:"GO:0097692"(histone H3-K4 monomethylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR024657|interpro:IPR034468|interpro:IPR035979|interpro:IPR037842|interpro:IPR044570|ensembl:ENSG00000139718(gene)|ensembl:ENST00000604567(transcript)|ensembl:ENST00000619791(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|mint:Q9UPS6|rcsb pdb:3UVO|rcsb pdb:4ES0|reactome:R-HSA-3214841|reactome:R-HSA-8936459 - - comment:"author score: 29" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZUYI3M78nGeeb8K2eIiDSw1uWeo9606 rogid:ZUY82C1+39tPg4n/f61PDe3DlGo9606 rigid:d7MNx4LvTBfadpFsgKxFZJi2uok false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UBL3 uniprotkb:O43684 intact:EBI-540797|uniprotkb:O60659|uniprotkb:O60660|uniprotkb:Q96B62|ensembl:ENSP00000340896|uniprotkb:A8K7C3|uniprotkb:D3DSW9 intact:EBI-1050987|uniprotkb:O43685|uniprotkb:B2R6E7|uniprotkb:A6NJ42|uniprotkb:D3DRE9|ensembl:ENSP00000357858 psi-mi:ash2l_human(display_long)|uniprotkb:ASH2-like protein(gene name synonym)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym) psi-mi:bub3_human(display_long)|uniprotkb:BUB3(gene name)|psi-mi:BUB3(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476274|imex:IM-26985-527 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001098684.1|refseq:NP_004665.2|ensembl:ENSG00000129691(gene)|ensembl:ENST00000343823(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|mint:Q9UBL3|rcsb pdb:3RSN|rcsb pdb:3S32|rcsb pdb:3TOJ|rcsb pdb:4RIQ|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6E2H|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|rcsb pdb:4X8N|refseq:NP_001248761.1|dip:DIP-29222N refseq:NP_001007794.1|refseq:NP_004716.1|ensembl:ENSG00000154473(gene)|ensembl:ENST00000368865(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR020472|interpro:IPR036322|mint:O43684|reactome:R-HSA-141430|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|reactome:R-HSA-141444|reactome:R-HSA-174184|reactome:R-HSA-176409|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|reactome:R-HSA-68877|reactome:R-HSA-9648025|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:1990298"(bub1-bub3 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|dip:DIP-24205N - - comment:"author score: 29" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZUYI3M78nGeeb8K2eIiDSw1uWeo9606 rogid:nqzARPql2cThSUpxSb6PuTRn51E9606 rigid:d7MNx4LvTBfadpFsgKxFZJi2uok false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UBL3 uniprotkb:Q6UXN9 intact:EBI-540797|uniprotkb:O60659|uniprotkb:O60660|uniprotkb:Q96B62|ensembl:ENSP00000340896|uniprotkb:A8K7C3|uniprotkb:D3DSW9 intact:EBI-1176082|uniprotkb:Q8TEB2|uniprotkb:A8K5R5|intact:EBI-2562464|ensembl:ENSP00000296490 psi-mi:ash2l_human(display_long)|uniprotkb:ASH2-like protein(gene name synonym)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym) psi-mi:wdr82_human(display_long)|uniprotkb:Protein TMEM113(gene name synonym)|uniprotkb:TMEM113(gene name synonym)|uniprotkb:WDR82(gene name)|psi-mi:WDR82(display_short)|uniprotkb:Swd2(gene name synonym)|uniprotkb:WDR82A(gene name synonym)|uniprotkb:UNQ9342/PRO34047(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476274|imex:IM-26985-527 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001098684.1|refseq:NP_004665.2|ensembl:ENSG00000129691(gene)|ensembl:ENST00000343823(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|mint:Q9UBL3|rcsb pdb:3RSN|rcsb pdb:3S32|rcsb pdb:3TOJ|rcsb pdb:4RIQ|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6E2H|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|rcsb pdb:4X8N|refseq:NP_001248761.1|dip:DIP-29222N refseq:NP_079498.2|ensembl:ENSG00000164091(gene)|ensembl:ENST00000296490(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005730"(nucleolus)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|interpro:IPR037867|mint:Q6UXN9 - - comment:"author score: 35" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZUYI3M78nGeeb8K2eIiDSw1uWeo9606 rogid:0TyKYwpTLd22Cm+ihT1+n0oo12c9606 rigid:d7MNx4LvTBfadpFsgKxFZJi2uok false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UBL3 uniprotkb:O00255 intact:EBI-540797|uniprotkb:O60659|uniprotkb:O60660|uniprotkb:Q96B62|ensembl:ENSP00000340896|uniprotkb:A8K7C3|uniprotkb:D3DSW9 intact:EBI-592789|uniprotkb:O00632|uniprotkb:Q9BUK2|uniprotkb:A5HBC6|uniprotkb:A5HBC7|uniprotkb:A5HBC8|uniprotkb:A5HBC9|uniprotkb:A5HBD0|uniprotkb:A5HBD1|uniprotkb:A5HBD2|uniprotkb:Q9BUF0|ensembl:ENSP00000366530 psi-mi:ash2l_human(display_long)|uniprotkb:ASH2-like protein(gene name synonym)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym) psi-mi:men1_human(display_long)|uniprotkb:MEN1(gene name)|psi-mi:MEN1(display_short)|uniprotkb:SCG2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476274|imex:IM-26985-527 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001098684.1|refseq:NP_004665.2|ensembl:ENSG00000129691(gene)|ensembl:ENST00000343823(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|mint:Q9UBL3|rcsb pdb:3RSN|rcsb pdb:3S32|rcsb pdb:3TOJ|rcsb pdb:4RIQ|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6E2H|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|rcsb pdb:4X8N|refseq:NP_001248761.1|dip:DIP-29222N refseq:NP_000235.2|refseq:NP_570711.1|refseq:NP_570712.1|refseq:NP_570713.1|refseq:NP_570714.1|refseq:NP_570715.1|refseq:NP_570716.1|refseq:XP_005274058.1|refseq:XP_016873258.1|refseq:XP_016873259.1|dip:DIP-24236N|ensembl:ENSG00000133895(gene)|ensembl:ENST00000377313(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002076"(osteoblast development)|go:"GO:0003309"(type B pancreatic cell differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009411"(response to UV)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032925"(regulation of activin receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046697"(decidualization)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0061469"(regulation of type B pancreatic cell proliferation)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071559"(response to transforming growth factor beta)|go:"GO:1902807"(negative regulation of cell cycle G1/S phase transition)|interpro:IPR007747(Menin)|mint:O00255|rcsb pdb:3U84|rcsb pdb:3U85|rcsb pdb:3U86|rcsb pdb:3U88|rcsb pdb:4GPQ|rcsb pdb:4GQ3|rcsb pdb:4GQ4|rcsb pdb:4GQ6|rcsb pdb:4I80|rcsb pdb:4OG3|rcsb pdb:4OG4|rcsb pdb:4OG5|rcsb pdb:4OG6|rcsb pdb:4OG7|rcsb pdb:4OG8|rcsb pdb:4X5Y|rcsb pdb:4X5Z|rcsb pdb:5DB0|rcsb pdb:5DB1|rcsb pdb:5DB2|rcsb pdb:5DB3|rcsb pdb:5DD9|rcsb pdb:5DDA|rcsb pdb:5DDB|rcsb pdb:5DDC|rcsb pdb:5DDD|rcsb pdb:5DDF|rcsb pdb:6B41|rcsb pdb:6BXH|rcsb pdb:6BXY|rcsb pdb:6BY8|rcsb pdb:6E1A|rcsb pdb:6O5I|rcsb pdb:6OPJ|rcsb pdb:6PKC|rcsb pdb:6WNH|reactome:R-HSA-201722|reactome:R-HSA-2173796|reactome:R-HSA-3769402|reactome:R-HSA-381426|reactome:R-HSA-5626467|reactome:R-HSA-8957275|rcsb pdb:5DDE - - comment:"author score: 45" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZUYI3M78nGeeb8K2eIiDSw1uWeo9606 rogid:gXAt4cxheS3wgMbFtc8ACfkHRH09606 rigid:d7MNx4LvTBfadpFsgKxFZJi2uok false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UBL3 uniprotkb:P51610 intact:EBI-540797|uniprotkb:O60659|uniprotkb:O60660|uniprotkb:Q96B62|ensembl:ENSP00000340896|uniprotkb:A8K7C3|uniprotkb:D3DSW9 intact:EBI-396176|intact:EBI-2832627|uniprotkb:Q6P4G5|intact:EBI-12037257|intact:EBI-14324845|ensembl:ENSP00000309555|intact:EBI-12980473 psi-mi:ash2l_human(display_long)|uniprotkb:ASH2-like protein(gene name synonym)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym) psi-mi:hcfc1_human(display_long)|uniprotkb:HCFC1(gene name)|psi-mi:HCFC1(display_short)|uniprotkb:HCF1(gene name synonym)|uniprotkb:C1 factor(gene name synonym)|uniprotkb:VP16 accessory protein(gene name synonym)|uniprotkb:VCAF(gene name synonym)|uniprotkb:CFF(gene name synonym)|uniprotkb:HFC1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476274|imex:IM-26985-527 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001098684.1|refseq:NP_004665.2|ensembl:ENSG00000129691(gene)|ensembl:ENST00000343823(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|mint:Q9UBL3|rcsb pdb:3RSN|rcsb pdb:3S32|rcsb pdb:3TOJ|rcsb pdb:4RIQ|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6E2H|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|rcsb pdb:4X8N|refseq:NP_001248761.1|dip:DIP-29222N refseq:NP_005325.2|refseq:XP_006724879.1|rcsb pdb:6MA1|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|reactome:R-HSA-2151201|reactome:R-HSA-3214847|reactome:R-HSA-5689603|ensembl:ENSG00000172534(gene)|ensembl:ENST00000310441(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019046"(release from viral latency)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR036116|interpro:IPR037854|interpro:IPR043536|mint:P51610|rcsb pdb:4GO6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:5LWV|dip:DIP-32955N - - comment:"author score: 49" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZUYI3M78nGeeb8K2eIiDSw1uWeo9606 rogid:RzsCRe9l6md3DI87H4ZgdR9oBMI9606 rigid:d7MNx4LvTBfadpFsgKxFZJi2uok false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UBL3 uniprotkb:Q14686 intact:EBI-540797|uniprotkb:O60659|uniprotkb:O60660|uniprotkb:Q96B62|ensembl:ENSP00000340896|uniprotkb:A8K7C3|uniprotkb:D3DSW9 intact:EBI-78670|uniprotkb:A6NLF1|uniprotkb:Q9NTZ9|uniprotkb:Q9UH74|uniprotkb:Q9UK86|ensembl:ENSP00000351894|ensembl:ENSP00000363929|uniprotkb:B2RMN5|uniprotkb:E1P5P7 psi-mi:ash2l_human(display_long)|uniprotkb:ASH2-like protein(gene name synonym)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym) psi-mi:ncoa6_human(display_long)|uniprotkb:NCOA6(gene name)|psi-mi:NCOA6(display_short)|uniprotkb:KIAA0181(gene name synonym)|uniprotkb:RAP250(gene name synonym)|uniprotkb:Amplified in breast cancer protein 3(gene name synonym)|uniprotkb:Cancer-amplified transcriptional coactivator ASC-2(gene name synonym)|uniprotkb:Activating signal cointegrator 2(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-interacting protein(gene name synonym)|uniprotkb:Nuclear receptor-activating protein, 250 kDa(gene name synonym)|uniprotkb:Nuclear receptor coactivator RAP250(gene name synonym)|uniprotkb:Thyroid hormone receptor-binding protein(gene name synonym)|uniprotkb:AIB3(gene name synonym)|uniprotkb:TRBP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476274|imex:IM-26985-527 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001098684.1|refseq:NP_004665.2|ensembl:ENSG00000129691(gene)|ensembl:ENST00000343823(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|mint:Q9UBL3|rcsb pdb:3RSN|rcsb pdb:3S32|rcsb pdb:3TOJ|rcsb pdb:4RIQ|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6E2H|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|rcsb pdb:4X8N|refseq:NP_001248761.1|dip:DIP-29222N refseq:NP_001229468.1|refseq:NP_054790.2|ensembl:ENSG00000198646(gene)|ensembl:ENST00000359003(transcript)|ensembl:ENST00000374796(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0009725"(response to hormone)|go:"GO:0019899"(enzyme binding)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051427"(hormone receptor binding)|interpro:IPR026638|interpro:IPR032715|mint:Q14686|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-5617472|reactome:R-HSA-9707564|reactome:R-HSA-9707616|ensembl:ENSP00000351894|ensembl:ENSP00000363929|refseq:NP_001305169.1|dip:DIP-30934N - - comment:"author score: 52" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZUYI3M78nGeeb8K2eIiDSw1uWeo9606 rogid:0PZz93t/oHYDVeiX+8NqjSlpNRo9606 rigid:d7MNx4LvTBfadpFsgKxFZJi2uok false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UBL3 uniprotkb:Q6ZW49 intact:EBI-540797|uniprotkb:O60659|uniprotkb:O60660|uniprotkb:Q96B62|ensembl:ENSP00000340896|uniprotkb:A8K7C3|uniprotkb:D3DSW9 intact:EBI-743225|ensembl:ENSP00000380376|ensembl:ENSP00000384048|uniprotkb:O15404|uniprotkb:Q6N099|uniprotkb:Q6ZWH9|uniprotkb:Q7Z315|uniprotkb:Q86UN0|uniprotkb:Q8N4P9|uniprotkb:Q96HP2 psi-mi:ash2l_human(display_long)|uniprotkb:ASH2-like protein(gene name synonym)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym) psi-mi:paxi1_human(display_long)|uniprotkb:PAX transactivation activation domain-interacting protein(gene name synonym)|uniprotkb:PAXIP1(gene name)|psi-mi:PAXIP1(display_short)|uniprotkb:PAXIP1L(gene name synonym)|uniprotkb:PTIP(gene name synonym)|uniprotkb:CAGF28(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476274|imex:IM-26985-527 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001098684.1|refseq:NP_004665.2|ensembl:ENSG00000129691(gene)|ensembl:ENST00000343823(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|mint:Q9UBL3|rcsb pdb:3RSN|rcsb pdb:3S32|rcsb pdb:3TOJ|rcsb pdb:4RIQ|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6E2H|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|rcsb pdb:4X8N|refseq:NP_001248761.1|dip:DIP-29222N go:"GO:0006310"(DNA recombination)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060717"(chorion development)|go:"GO:1902749"(regulation of cell cycle G2/M phase transition)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR001357(BRCT)|interpro:IPR036420|interpro:IPR037886|mint:Q6ZW49|rcsb pdb:3SQD|reactome:R-HSA-5617472|reactome:R-HSA-5693571|refseq:NP_031375.3|ensembl:ENSG00000157212(gene)|ensembl:ENST00000397192(transcript)|ensembl:ENST00000404141(transcript)|go:"GO:0000416"(positive regulation of histone H3-K36 methylation)|go:"GO:0001570"(vasculogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006281"(DNA repair)|refseq:XP_005249596.1|refseq:XP_016867370.1|dip:DIP-41786N - - comment:"author score: 66" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZUYI3M78nGeeb8K2eIiDSw1uWeo9606 rogid:djzoPtMxXMP9LBvpzVNBcq04QEY9606 rigid:d7MNx4LvTBfadpFsgKxFZJi2uok false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UBL3 uniprotkb:Q9Y5Z7 intact:EBI-540797|uniprotkb:O60659|uniprotkb:O60660|uniprotkb:Q96B62|ensembl:ENSP00000340896|uniprotkb:A8K7C3|uniprotkb:D3DSW9 intact:EBI-592728|uniprotkb:B2R8Q5|uniprotkb:C0H5X3|ensembl:ENSP00000229330 psi-mi:ash2l_human(display_long)|uniprotkb:ASH2-like protein(gene name synonym)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym) psi-mi:hcfc2_human(display_long)|uniprotkb:C2 factor(gene name synonym)|uniprotkb:HCFC2(gene name)|psi-mi:HCFC2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476274|imex:IM-26985-527 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001098684.1|refseq:NP_004665.2|ensembl:ENSG00000129691(gene)|ensembl:ENST00000343823(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|mint:Q9UBL3|rcsb pdb:3RSN|rcsb pdb:3S32|rcsb pdb:3TOJ|rcsb pdb:4RIQ|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6E2H|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|rcsb pdb:4X8N|refseq:NP_001248761.1|dip:DIP-29222N refseq:NP_037452.1|ensembl:ENSG00000111727(gene)|ensembl:ENST00000229330(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016032"(viral process)|go:"GO:0016604"(nuclear body)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0071339"(MLL1 complex)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR036116|interpro:IPR037932|interpro:IPR043536|mint:Q9Y5Z7 - - comment:"author score: 75" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZUYI3M78nGeeb8K2eIiDSw1uWeo9606 rogid:ytE7Aid9JO9RWsRpJPpBbylLRXo9606 rigid:d7MNx4LvTBfadpFsgKxFZJi2uok false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UBL3 uniprotkb:Q8NEZ4 intact:EBI-540797|uniprotkb:O60659|uniprotkb:O60660|uniprotkb:Q96B62|ensembl:ENSP00000340896|uniprotkb:A8K7C3|uniprotkb:D3DSW9 intact:EBI-1042997|uniprotkb:Q8NC02|uniprotkb:Q8NDF6|uniprotkb:Q9H9P4|uniprotkb:Q9NR13|uniprotkb:Q9P222|uniprotkb:Q9UDR7|ensembl:ENSP00000262189 psi-mi:ash2l_human(display_long)|uniprotkb:ASH2-like protein(gene name synonym)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym) psi-mi:kmt2c_human(display_long)|uniprotkb:KMT2C(gene name)|psi-mi:KMT2C(display_short)|uniprotkb:HALR(gene name synonym)|uniprotkb:Homologous to ALR protein(gene name synonym)|uniprotkb:KIAA1506(gene name synonym)|uniprotkb:MLL3(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476274|imex:IM-26985-527 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001098684.1|refseq:NP_004665.2|ensembl:ENSG00000129691(gene)|ensembl:ENST00000343823(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|mint:Q9UBL3|rcsb pdb:3RSN|rcsb pdb:3S32|rcsb pdb:3TOJ|rcsb pdb:4RIQ|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6E2H|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|rcsb pdb:4X8N|refseq:NP_001248761.1|dip:DIP-29222N ensembl:ENSG00000055609(gene)|ensembl:ENST00000262189(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042393"(histone binding)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0097692"(histone H3-K4 monomethylation)|interpro:IPR000637(HMG-I and HMG-Y, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|go:"GO:0005634"(nucleus)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036910|interpro:IPR037877|interpro:IPR041967|interpro:IPR041968|mint:Q8NEZ4|rcsb pdb:2YSM|rcsb pdb:2YUK|rcsb pdb:3UVL|rcsb pdb:4ERY|rcsb pdb:5F59|rcsb pdb:5F6K|rcsb pdb:6KIW|rcsb pdb:6MLC|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8936459|refseq:NP_733751.2|ensembl:ENSP00000262189|ensembl:ENST00000682283|ensembl:ENSP00000507485|dip:DIP-48649N - - comment:"author score: 80" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZUYI3M78nGeeb8K2eIiDSw1uWeo9606 rogid:NZg8HgfbohMT8EEgAdAgWR1AjSo9606 rigid:d7MNx4LvTBfadpFsgKxFZJi2uok false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UBL3 uniprotkb:O15047 intact:EBI-540797|uniprotkb:O60659|uniprotkb:O60660|uniprotkb:Q96B62|ensembl:ENSP00000340896|uniprotkb:A8K7C3|uniprotkb:D3DSW9 intact:EBI-540779|uniprotkb:A6NP62|uniprotkb:Q6PIF3|uniprotkb:Q8TAJ6|intact:EBI-28969638|ensembl:ENSP00000262519|ensembl:ENSP00000507683 psi-mi:ash2l_human(display_long)|uniprotkb:ASH2-like protein(gene name synonym)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym) psi-mi:set1a_human(display_long)|uniprotkb:KMT2F(gene name synonym)|uniprotkb:SET domain-containing protein 1A(gene name synonym)|uniprotkb:Set1/Ash2 histone methyltransferase complex subunit SET1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 2F(gene name synonym)|uniprotkb:SETD1A(gene name)|psi-mi:SETD1A(display_short)|uniprotkb:KIAA0339(gene name synonym)|uniprotkb:SET1(gene name synonym)|uniprotkb:SET1A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476274|imex:IM-26985-527 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001098684.1|refseq:NP_004665.2|ensembl:ENSG00000129691(gene)|ensembl:ENST00000343823(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|mint:Q9UBL3|rcsb pdb:3RSN|rcsb pdb:3S32|rcsb pdb:3TOJ|rcsb pdb:4RIQ|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6E2H|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|rcsb pdb:4X8N|refseq:NP_001248761.1|dip:DIP-29222N refseq:NP_055527.1|refseq:XP_006721169.1|ensembl:ENSP00000262519|ensembl:ENSP00000507683|reactome:R-HSA-8936459|reactome:R-HSA-3214841|ensembl:ENSG00000099381(gene)|ensembl:ENST00000262519(transcript)|ensembl:ENST00000684162(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007420"(brain development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR024657|interpro:IPR034467|interpro:IPR035979|interpro:IPR037841|interpro:IPR044570|mint:O15047|go:"GO:0048188"(Set1C/COMPASS complex)|rcsb pdb:3S8S|rcsb pdb:3UVN|rcsb pdb:4EWR|refseq:XP_005255780.1|refseq:XP_016879398.1|dip:DIP-33494N - - comment:"author score: 85" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZUYI3M78nGeeb8K2eIiDSw1uWeo9606 rogid:nx0uWEVFas1w2NmuG73lCObAULE9606 rigid:d7MNx4LvTBfadpFsgKxFZJi2uok false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UBL3 uniprotkb:Q03164 intact:EBI-540797|uniprotkb:O60659|uniprotkb:O60660|uniprotkb:Q96B62|ensembl:ENSP00000340896|uniprotkb:A8K7C3|uniprotkb:D3DSW9 intact:EBI-591370|ensembl:ENSP00000374157|uniprotkb:Q13743|uniprotkb:Q13744|uniprotkb:Q14845|uniprotkb:Q16364|uniprotkb:Q6UBD1|uniprotkb:Q9UMA3|intact:EBI-2614650|uniprotkb:Q59FF2|uniprotkb:Q9UD94|uniprotkb:E9PQG7|uniprotkb:Q9HBJ3 psi-mi:ash2l_human(display_long)|uniprotkb:ASH2-like protein(gene name synonym)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym) psi-mi:kmt2a_human(display_long)|uniprotkb:KMT2A(gene name)|psi-mi:KMT2A(display_short)|uniprotkb:ALL-1(gene name synonym)|uniprotkb:ALL1(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 7(gene name synonym)|uniprotkb:CXXC7(gene name synonym)|uniprotkb:HRX(gene name synonym)|uniprotkb:HTRX(gene name synonym)|uniprotkb:MLL(gene name synonym)|uniprotkb:MLL1(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 1(gene name synonym)|uniprotkb:TRX1(gene name synonym)|uniprotkb:Trithorax-like protein(gene name synonym)|uniprotkb:Zinc finger protein HRX(gene name synonym)|uniprotkb:Cysteine methyltransferase KMT2A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476274|imex:IM-26985-527 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001098684.1|refseq:NP_004665.2|ensembl:ENSG00000129691(gene)|ensembl:ENST00000343823(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|mint:Q9UBL3|rcsb pdb:3RSN|rcsb pdb:3S32|rcsb pdb:3TOJ|rcsb pdb:4RIQ|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6E2H|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|rcsb pdb:4X8N|refseq:NP_001248761.1|dip:DIP-29222N go:"GO:2000615"(regulation of histone H3-K9 acetylation)|interpro:IPR001214(SET)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016569(Methyltransferase, trithorax)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036427|interpro:IPR037927|interpro:IPR041958|interpro:IPR042023|interpro:IPR042025|interpro:IPR044133|mint:Q03164|rcsb pdb:2AGH|rcsb pdb:2J2S|rcsb pdb:2JYI|rcsb pdb:2KKF|rcsb pdb:2KU7|rcsb pdb:2KYU|rcsb pdb:2LXS|rcsb pdb:2LXT|rcsb pdb:2MSR|rcsb pdb:2MTN|rcsb pdb:2W5Y|ensembl:ENSG00000118058(gene)|ensembl:ENST00000389506(transcript)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032411"(positive regulation of transporter activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071440"(regulation of histone H3-K14 acetylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:0106363"(protein-cysteine methyltransferase activity)|go:"GO:1905642"(negative regulation of DNA methylation)|refseq:NP_001184033.1|refseq:NP_005924.2|ensembl:ENSP00000374157|ensembl:ENST00000534358|ensembl:ENSP00000436786|ensembl:ENST00000649699|ensembl:ENSP00000496927|dip:DIP-29221N|rcsb pdb:2W5Z|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3LQH|rcsb pdb:3LQI|rcsb pdb:3LQJ|rcsb pdb:3P4F|rcsb pdb:3U85|rcsb pdb:3U88|rcsb pdb:4ESG|rcsb pdb:4GQ6|rcsb pdb:4NW3|rcsb pdb:5F5E|rcsb pdb:5F6L|rcsb pdb:5SVH|rcsb pdb:6EMQ|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U9K|rcsb pdb:6U9M|rcsb pdb:6U9N|rcsb pdb:6U9R|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|reactome:R-HSA-3214841|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9616222 - - comment:"author score: 86" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZUYI3M78nGeeb8K2eIiDSw1uWeo9606 rogid:r9J9pjnLZI7GCBSHYqnmzjv9WvM9606 rigid:d7MNx4LvTBfadpFsgKxFZJi2uok false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UBL3 uniprotkb:O14686 intact:EBI-540797|uniprotkb:O60659|uniprotkb:O60660|uniprotkb:Q96B62|ensembl:ENSP00000340896|uniprotkb:A8K7C3|uniprotkb:D3DSW9 intact:EBI-996065|uniprotkb:O14687|intact:EBI-28986759|ensembl:ENSP00000301067 psi-mi:ash2l_human(display_long)|uniprotkb:ASH2-like protein(gene name synonym)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym) psi-mi:kmt2d_human(display_long)|uniprotkb:KMT2D(gene name)|psi-mi:KMT2D(display_short)|uniprotkb:ALL1-related protein(gene name synonym)|uniprotkb:ALR(gene name synonym)|uniprotkb:MLL2(gene name synonym)|uniprotkb:MLL4(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476274|imex:IM-26985-527 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001098684.1|refseq:NP_004665.2|ensembl:ENSG00000129691(gene)|ensembl:ENST00000343823(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|mint:Q9UBL3|rcsb pdb:3RSN|rcsb pdb:3S32|rcsb pdb:3TOJ|rcsb pdb:4RIQ|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6E2H|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|rcsb pdb:4X8N|refseq:NP_001248761.1|dip:DIP-29222N refseq:NP_003473.3|refseq:XP_006719677.1|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0043627"(response to estrogen)|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:1904837"(beta-catenin-TCF complex assembly)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR009071(High mobility group box, HMG)|ensembl:ENSG00000167548(gene)|ensembl:ENST00000301067(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001555"(oocyte growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|interpro:IPR036910|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR037890|interpro:IPR041961|interpro:IPR041964|mint:O14686|rcsb pdb:3UVK|rcsb pdb:4ERQ|rcsb pdb:4Z4P|rcsb pdb:6O7G|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR034732|ensembl:ENSP00000301067|refseq:XP_005269219.1|dip:DIP-37875N - - comment:"author score: 88" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZUYI3M78nGeeb8K2eIiDSw1uWeo9606 rogid:eaCGHR6OqxzL66VYfOrzBWJApHY9606 rigid:d7MNx4LvTBfadpFsgKxFZJi2uok false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UBL3 uniprotkb:Q9UMN6 intact:EBI-540797|uniprotkb:O60659|uniprotkb:O60660|uniprotkb:Q96B62|ensembl:ENSP00000340896|uniprotkb:A8K7C3|uniprotkb:D3DSW9 intact:EBI-765774|uniprotkb:O15022|uniprotkb:O95836|uniprotkb:Q96GP2|uniprotkb:Q96IP3|uniprotkb:Q9UK25|uniprotkb:Q9Y668|uniprotkb:Q9Y669|ensembl:ENSP00000398837 psi-mi:ash2l_human(display_long)|uniprotkb:ASH2-like protein(gene name synonym)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym) psi-mi:kmt2b_human(display_long)|uniprotkb:KMT2B(gene name)|psi-mi:KMT2B(display_short)|uniprotkb:HRX2(gene name synonym)|uniprotkb:KIAA0304(gene name synonym)|uniprotkb:MLL2(gene name synonym)|uniprotkb:MLL4(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 4(gene name synonym)|uniprotkb:TRX2(gene name synonym)|uniprotkb:Trithorax homolog 2(gene name synonym)|uniprotkb:WBP7(gene name synonym)|uniprotkb:WW domain-binding protein 7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476274|imex:IM-26985-527 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001098684.1|refseq:NP_004665.2|ensembl:ENSG00000129691(gene)|ensembl:ENST00000343823(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|mint:Q9UBL3|rcsb pdb:3RSN|rcsb pdb:3S32|rcsb pdb:3TOJ|rcsb pdb:4RIQ|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6E2H|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|rcsb pdb:4X8N|refseq:NP_001248761.1|dip:DIP-29222N ensembl:ENSP00000398837|dip:DIP-34598N|ensembl:ENSG00000272333(gene)|ensembl:ENST00000420124(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|interpro:IPR001214(SET)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016569(Methyltransferase, trithorax)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036427|interpro:IPR041959|mint:Q9UMN6|rcsb pdb:3UVM|rcsb pdb:4ERZ|rcsb pdb:4PZI|rcsb pdb:7BRE|reactome:R-HSA-3214841|reactome:R-HSA-8936459 - - comment:"author score: 89" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZUYI3M78nGeeb8K2eIiDSw1uWeo9606 rogid:1Im1Dqkyg85ZGqrxLaK4wyMVGNY9606 rigid:d7MNx4LvTBfadpFsgKxFZJi2uok false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UBL3 uniprotkb:Q9P0U4 intact:EBI-540797|uniprotkb:O60659|uniprotkb:O60660|uniprotkb:Q96B62|ensembl:ENSP00000340896|uniprotkb:A8K7C3|uniprotkb:D3DSW9 intact:EBI-949911|ensembl:ENSP00000285106|uniprotkb:Q8N2W4|uniprotkb:Q96BC8|uniprotkb:Q9P2V7|uniprotkb:B2RC03 psi-mi:ash2l_human(display_long)|uniprotkb:ASH2-like protein(gene name synonym)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym) psi-mi:cxxc1_human(display_long)|uniprotkb:CFP1(gene name synonym)|uniprotkb:PHD finger and CXXC domain-containing protein 1(gene name synonym)|uniprotkb:CXXC1(gene name)|psi-mi:CXXC1(display_short)|uniprotkb:CGBP(gene name synonym)|uniprotkb:PCCX1(gene name synonym)|uniprotkb:PHF18(gene name synonym)|uniprotkb:CpG-binding protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476274|imex:IM-26985-527 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001098684.1|refseq:NP_004665.2|ensembl:ENSG00000129691(gene)|ensembl:ENST00000343823(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|mint:Q9UBL3|rcsb pdb:3RSN|rcsb pdb:3S32|rcsb pdb:3TOJ|rcsb pdb:4RIQ|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6E2H|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|rcsb pdb:4X8N|refseq:NP_001248761.1|dip:DIP-29222N ensembl:ENSG00000154832(gene)|ensembl:ENST00000285106(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|reactome:R-HSA-381038|interpro:IPR022056|interpro:IPR037869|mint:Q9P0U4|rcsb pdb:3QMB|rcsb pdb:3QMC|rcsb pdb:3QMD|rcsb pdb:3QMG|rcsb pdb:3QMH|rcsb pdb:3QMI|refseq:NP_001095124.1|refseq:NP_055408.2|refseq:XP_011524242.1|refseq:XP_016881207.1|dip:DIP-50001N - - comment:"author score: 128" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZUYI3M78nGeeb8K2eIiDSw1uWeo9606 rogid:nWwPX7OlafdCMD8Qg+hETjNkKgY9606 rigid:d7MNx4LvTBfadpFsgKxFZJi2uok false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UBL3 uniprotkb:Q9C005 intact:EBI-540797|uniprotkb:O60659|uniprotkb:O60660|uniprotkb:Q96B62|ensembl:ENSP00000340896|uniprotkb:A8K7C3|uniprotkb:D3DSW9 intact:EBI-744973|uniprotkb:D6W578|ensembl:ENSP00000295066|ensembl:ENSP00000345837 psi-mi:ash2l_human(display_long)|uniprotkb:ASH2-like protein(gene name synonym)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym) psi-mi:dpy30_human(display_long)|uniprotkb:DPY30(gene name)|psi-mi:DPY30(display_short)|uniprotkb:Dpy-30-like protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476274|imex:IM-26985-527 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001098684.1|refseq:NP_004665.2|ensembl:ENSG00000129691(gene)|ensembl:ENST00000343823(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|mint:Q9UBL3|rcsb pdb:3RSN|rcsb pdb:3S32|rcsb pdb:3TOJ|rcsb pdb:4RIQ|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6E2H|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|rcsb pdb:4X8N|refseq:NP_001248761.1|dip:DIP-29222N refseq:NP_115963.1|ensembl:ENSG00000162961(gene)|ensembl:ENST00000295066(transcript)|ensembl:ENST00000342166(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006348"|go:"GO:0016197"(endosomal transport)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|mint:Q9C005|rcsb pdb:3G36|rcsb pdb:4RIQ|rcsb pdb:4RT4|rcsb pdb:4RTA|rcsb pdb:6E2H|rcsb pdb:6PWV|reactome:R-HSA-3214841|reactome:R-HSA-8936459|refseq:NP_001308138.1|dip:DIP-34476N - - comment:"author score: 139" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZUYI3M78nGeeb8K2eIiDSw1uWeo9606 rogid:yC9NJhTfEIT+YyfWRSJLGbRsQkc9606 rigid:d7MNx4LvTBfadpFsgKxFZJi2uok false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UBL3 uniprotkb:O15550 intact:EBI-540797|uniprotkb:O60659|uniprotkb:O60660|uniprotkb:Q96B62|ensembl:ENSP00000340896|uniprotkb:A8K7C3|uniprotkb:D3DSW9 intact:EBI-4292203|uniprotkb:Q52LL9|uniprotkb:Q5JVQ7|intact:EBI-28988602|ensembl:ENSP00000367203 psi-mi:ash2l_human(display_long)|uniprotkb:ASH2-like protein(gene name synonym)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym) psi-mi:kdm6a_human(display_long)|uniprotkb:KDM6A(gene name)|psi-mi:KDM6A(display_short)|uniprotkb:UTX(gene name synonym)|uniprotkb:Histone demethylase UTX(gene name synonym)|uniprotkb:Ubiquitously-transcribed TPR protein on the X chromosome(gene name synonym)|uniprotkb:Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(27) demethylase 6A"(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476274|imex:IM-26985-527 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001098684.1|refseq:NP_004665.2|ensembl:ENSG00000129691(gene)|ensembl:ENST00000343823(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|mint:Q9UBL3|rcsb pdb:3RSN|rcsb pdb:3S32|rcsb pdb:3TOJ|rcsb pdb:4RIQ|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6E2H|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|rcsb pdb:4X8N|refseq:NP_001248761.1|dip:DIP-29222N refseq:NP_066963.2|ensembl:ENSG00000147050(gene)|ensembl:ENST00000377967(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007507"(heart development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071557"(histone H3-K27 demethylation)|go:"GO:0071558"(histone H3-tri/di-methyl-lysine-27 demethylase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:O15550|rcsb pdb:3AVR|rcsb pdb:3AVS|rcsb pdb:6FUK|rcsb pdb:6FUL|reactome:R-HSA-3214842|reactome:R-HSA-5617472|ensembl:ENSP00000367203|dip:DIP-46192N - - comment:"author score: 178" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZUYI3M78nGeeb8K2eIiDSw1uWeo9606 rogid:sqg+Ikkgvz0uT/gMx1wYs9FaDbI9606 rigid:d7MNx4LvTBfadpFsgKxFZJi2uok false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UBL3 uniprotkb:P61964 intact:EBI-540797|uniprotkb:O60659|uniprotkb:O60660|uniprotkb:Q96B62|ensembl:ENSP00000340896|uniprotkb:A8K7C3|uniprotkb:D3DSW9 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 psi-mi:ash2l_human(display_long)|uniprotkb:ASH2-like protein(gene name synonym)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym) psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476274|imex:IM-26985-527 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001098684.1|refseq:NP_004665.2|ensembl:ENSG00000129691(gene)|ensembl:ENST00000343823(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|mint:Q9UBL3|rcsb pdb:3RSN|rcsb pdb:3S32|rcsb pdb:3TOJ|rcsb pdb:4RIQ|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6E2H|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|rcsb pdb:4X8N|refseq:NP_001248761.1|dip:DIP-29222N refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N - - comment:"author score: 208" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZUYI3M78nGeeb8K2eIiDSw1uWeo9606 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rigid:d7MNx4LvTBfadpFsgKxFZJi2uok false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UBL3 uniprotkb:Q15291 intact:EBI-540797|uniprotkb:O60659|uniprotkb:O60660|uniprotkb:Q96B62|ensembl:ENSP00000340896|uniprotkb:A8K7C3|uniprotkb:D3DSW9 intact:EBI-592823|uniprotkb:A8K272|uniprotkb:Q7Z6D8|uniprotkb:Q8NDZ7|ensembl:ENSP00000264515 psi-mi:ash2l_human(display_long)|uniprotkb:ASH2-like protein(gene name synonym)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym) psi-mi:rbbp5_human(display_long)|uniprotkb:Retinoblastoma-binding protein RBQ-3(gene name synonym)|uniprotkb:RBBP5(gene name)|psi-mi:RBBP5(display_short)|uniprotkb:RBQ3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476274|imex:IM-26985-527 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001098684.1|refseq:NP_004665.2|ensembl:ENSG00000129691(gene)|ensembl:ENST00000343823(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|mint:Q9UBL3|rcsb pdb:3RSN|rcsb pdb:3S32|rcsb pdb:3TOJ|rcsb pdb:4RIQ|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6E2H|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|rcsb pdb:4X8N|refseq:NP_001248761.1|dip:DIP-29222N refseq:NP_001180201.1|refseq:NP_001180202.1|refseq:NP_005048.2|dip:DIP-29224N|ensembl:ENSG00000117222(gene)|ensembl:ENST00000264515(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037850|mint:Q15291|rcsb pdb:3P4F|rcsb pdb:4X8N|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6KM7|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6PWX|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664 - - comment:"author score: 209" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZUYI3M78nGeeb8K2eIiDSw1uWeo9606 rogid:Zl8yHcbL1C6StHPyD+875Ccy6gk9606 rigid:d7MNx4LvTBfadpFsgKxFZJi2uok false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WXE1 uniprotkb:P09132 intact:EBI-747353|uniprotkb:Q8NHQ2|uniprotkb:Q8WUG7|uniprotkb:Q96CL3|uniprotkb:Q9HA30|uniprotkb:A8K6A3|uniprotkb:A8K714|uniprotkb:B2RCE7|uniprotkb:Q69YK9|uniprotkb:B4DU92|uniprotkb:B5MEB7|ensembl:ENSP00000323099 intact:EBI-2680090|uniprotkb:B2R4E9|uniprotkb:Q96FG6|uniprotkb:Q05D77|uniprotkb:D6RCQ5|ensembl:ENSP00000424870 psi-mi:atrip_human(display_long)|uniprotkb:ATM and Rad3-related-interacting protein(gene name synonym)|uniprotkb:ATRIP(gene name)|psi-mi:ATRIP(display_short)|uniprotkb:AGS1(gene name synonym) psi-mi:srp19_human(display_long)|uniprotkb:SRP19(gene name)|psi-mi:SRP19(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476337|imex:IM-26985-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115542.2|refseq:NP_569055.1|dip:DIP-46495N|refseq:NP_001257951.1|refseq:NP_001257952.1|ensembl:ENSG00000164053(gene)|ensembl:ENST00000320211(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|interpro:IPR033349|mint:Q8WXE1|rcsb pdb:4IGK|rcsb pdb:4NB3|rcsb pdb:5YZ0|reactome:R-HSA-176187|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-69473 refseq:NP_001191123.1|refseq:NP_003126.1|refseq:NP_001191122.1|refseq:NP_001191125.1|ensembl:ENSG00000153037(gene)|ensembl:ENST00000505459(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006617"(SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition)|go:"GO:0008312"(7S RNA binding)|go:"GO:0048500"(signal recognition particle)|interpro:IPR002778(Signal recognition particle, SRP19 subunit)|interpro:IPR036521|mint:P09132|rcsb pdb:1JID|rcsb pdb:1MFQ|rcsb pdb:1RY1|rcsb pdb:2J37|rcsb pdb:3KTV|rcsb pdb:4P3E|rcsb pdb:5M73|rcsb pdb:7NFX|reactome:R-HSA-1799339|dip:DIP-41412N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:VVllxHySIT6EGlT6SQhPePAXbsI9606 rogid:yIFmf1q6m2wQt3eaiCc1dlIQXn89606 rigid:TRlHPpQaJwxuOATrxcN4GqqHKu0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WXE1 uniprotkb:Q7RTV0 intact:EBI-747353|uniprotkb:Q8NHQ2|uniprotkb:Q8WUG7|uniprotkb:Q96CL3|uniprotkb:Q9HA30|uniprotkb:A8K6A3|uniprotkb:A8K714|uniprotkb:B2RCE7|uniprotkb:Q69YK9|uniprotkb:B4DU92|uniprotkb:B5MEB7|ensembl:ENSP00000323099 intact:EBI-2555365|uniprotkb:Q9UH06|ensembl:ENSP00000216252 psi-mi:atrip_human(display_long)|uniprotkb:ATM and Rad3-related-interacting protein(gene name synonym)|uniprotkb:ATRIP(gene name)|psi-mi:ATRIP(display_short)|uniprotkb:AGS1(gene name synonym) psi-mi:phf5a_human(display_long)|uniprotkb:Splicing factor 3B-associated 14 kDa protein(gene name synonym)|uniprotkb:PHF5A(gene name)|psi-mi:PHF5A(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476337|imex:IM-26985-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115542.2|refseq:NP_569055.1|dip:DIP-46495N|refseq:NP_001257951.1|refseq:NP_001257952.1|ensembl:ENSG00000164053(gene)|ensembl:ENST00000320211(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|interpro:IPR033349|mint:Q8WXE1|rcsb pdb:4IGK|rcsb pdb:4NB3|rcsb pdb:5YZ0|reactome:R-HSA-176187|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-69473 refseq:NP_116147.1|ensembl:ENSG00000100410(gene)|ensembl:ENST00000216252(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR005345(PHF5-like)|mint:Q7RTV0|rcsb pdb:5IFE|rcsb pdb:5O9Z|rcsb pdb:5SYB|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:5ZYA|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|go:"GO:0048863"(stem cell differentiation) - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:VVllxHySIT6EGlT6SQhPePAXbsI9606 rogid:TrngLk+KyJ+qRs8HGvH1LZH2Tsg9606 rigid:TRlHPpQaJwxuOATrxcN4GqqHKu0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WXE1 uniprotkb:P05204 intact:EBI-747353|uniprotkb:Q8NHQ2|uniprotkb:Q8WUG7|uniprotkb:Q96CL3|uniprotkb:Q9HA30|uniprotkb:A8K6A3|uniprotkb:A8K714|uniprotkb:B2RCE7|uniprotkb:Q69YK9|uniprotkb:B4DU92|uniprotkb:B5MEB7|ensembl:ENSP00000323099 intact:EBI-1758689|uniprotkb:Q0VGD5|uniprotkb:Q6FGI5|uniprotkb:Q96C64|ensembl:ENSP00000355228|ensembl:ENSP00000481160 psi-mi:atrip_human(display_long)|uniprotkb:ATM and Rad3-related-interacting protein(gene name synonym)|uniprotkb:ATRIP(gene name)|psi-mi:ATRIP(display_short)|uniprotkb:AGS1(gene name synonym) psi-mi:hmgn2_human(display_long)|uniprotkb:HMGN2(gene name)|psi-mi:HMGN2(display_short)|uniprotkb:HMG17(gene name synonym)|uniprotkb:High mobility group nucleosome-binding domain-containing protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476337|imex:IM-26985-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115542.2|refseq:NP_569055.1|dip:DIP-46495N|refseq:NP_001257951.1|refseq:NP_001257952.1|ensembl:ENSG00000164053(gene)|ensembl:ENST00000320211(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|interpro:IPR033349|mint:Q8WXE1|rcsb pdb:4IGK|rcsb pdb:4NB3|rcsb pdb:5YZ0|reactome:R-HSA-176187|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-69473 refseq:NP_005508.1|ensembl:ENSG00000198830(gene)|ensembl:ENST00000361427(transcript)|ensembl:ENST00000619352(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000079(High mobility group protein HMG14 and HMG17)|mint:P05204 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:VVllxHySIT6EGlT6SQhPePAXbsI9606 rogid:j8Khsp7BUJh0L9SicpVNR8LP6ZU9606 rigid:TRlHPpQaJwxuOATrxcN4GqqHKu0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WXE1 uniprotkb:P05114 intact:EBI-747353|uniprotkb:Q8NHQ2|uniprotkb:Q8WUG7|uniprotkb:Q96CL3|uniprotkb:Q9HA30|uniprotkb:A8K6A3|uniprotkb:A8K714|uniprotkb:B2RCE7|uniprotkb:Q69YK9|uniprotkb:B4DU92|uniprotkb:B5MEB7|ensembl:ENSP00000323099 intact:EBI-3915525|uniprotkb:Q3KQR8|ensembl:ENSP00000370125 psi-mi:atrip_human(display_long)|uniprotkb:ATM and Rad3-related-interacting protein(gene name synonym)|uniprotkb:ATRIP(gene name)|psi-mi:ATRIP(display_short)|uniprotkb:AGS1(gene name synonym) psi-mi:hmgn1_human(display_long)|uniprotkb:HMGN1(gene name)|psi-mi:HMGN1(display_short)|uniprotkb:HMG14(gene name synonym)|uniprotkb:High mobility group nucleosome-binding domain-containing protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476337|imex:IM-26985-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115542.2|refseq:NP_569055.1|dip:DIP-46495N|refseq:NP_001257951.1|refseq:NP_001257952.1|ensembl:ENSG00000164053(gene)|ensembl:ENST00000320211(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|interpro:IPR033349|mint:Q8WXE1|rcsb pdb:4IGK|rcsb pdb:4NB3|rcsb pdb:5YZ0|reactome:R-HSA-176187|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-69473 refseq:NP_004956.5|ensembl:ENSG00000205581(gene)|ensembl:ENST00000380749(transcript)|go:"GO:0000720"(pyrimidine dimer repair by nucleotide-excision repair)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010224"(response to UV-B)|go:"GO:0010225"(response to UV-C)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0048597"(post-embryonic camera-type eye morphogenesis)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:1901666"(positive regulation of NAD+ ADP-ribosyltransferase activity)|interpro:IPR000079(High mobility group protein HMG14 and HMG17)|mint:P05114|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:VVllxHySIT6EGlT6SQhPePAXbsI9606 rogid:2Ns7EUwCgpj8Gj6uTuB1K6UZksc9606 rigid:TRlHPpQaJwxuOATrxcN4GqqHKu0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WXE1 uniprotkb:P58876 intact:EBI-747353|uniprotkb:Q8NHQ2|uniprotkb:Q8WUG7|uniprotkb:Q96CL3|uniprotkb:Q9HA30|uniprotkb:A8K6A3|uniprotkb:A8K714|uniprotkb:B2RCE7|uniprotkb:Q69YK9|uniprotkb:B4DU92|uniprotkb:B5MEB7|ensembl:ENSP00000323099 intact:EBI-4409942|ensembl:ENSP00000289316|ensembl:ENSP00000367008 psi-mi:atrip_human(display_long)|uniprotkb:ATM and Rad3-related-interacting protein(gene name synonym)|uniprotkb:ATRIP(gene name)|psi-mi:ATRIP(display_short)|uniprotkb:AGS1(gene name synonym) psi-mi:h2b1d_human(display_long)|uniprotkb:Histone H2B.b(gene name synonym)|uniprotkb:H2BC5(gene name)|psi-mi:H2BC5(display_short)|uniprotkb:H2B-clustered histone 5(gene name synonym)|uniprotkb:H2BFB(gene name synonym)|uniprotkb:HIRA-interacting protein 2(gene name synonym)|uniprotkb:HIRIP2(gene name synonym)|uniprotkb:HIST1H2BD(gene name synonym)|uniprotkb:Histone H2B.1 B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476337|imex:IM-26985-63 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115542.2|refseq:NP_569055.1|dip:DIP-46495N|refseq:NP_001257951.1|refseq:NP_001257952.1|ensembl:ENSG00000164053(gene)|ensembl:ENST00000320211(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|interpro:IPR033349|mint:Q8WXE1|rcsb pdb:4IGK|rcsb pdb:4NB3|rcsb pdb:5YZ0|reactome:R-HSA-176187|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-69473 refseq:NP_066407.1|refseq:NP_619790.1|ensembl:ENSG00000158373(gene)|ensembl:ENST00000289316(transcript)|ensembl:ENST00000377777(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P58876|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|go:"GO:0005634"(nucleus) - - comment:"author score: 36" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:VVllxHySIT6EGlT6SQhPePAXbsI9606 rogid:07VBw5MCphdkMydMOPSjVqpGriI9606 rigid:TRlHPpQaJwxuOATrxcN4GqqHKu0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14CW9 uniprotkb:Q9BWU0 intact:EBI-949215|ensembl:ENSP00000374035|ensembl:ENSP00000465614|uniprotkb:Q96N40|uniprotkb:Q9NPU5|uniprotkb:Q8IY68 intact:EBI-1999704|uniprotkb:A6NJ39|uniprotkb:Q4KMT1|uniprotkb:Q4KMX0|uniprotkb:Q7Z5Q9|uniprotkb:Q9NVN2|ensembl:ENSP00000323837|ensembl:ENSP00000479964 psi-mi:at7l3_human(display_long)|uniprotkb:ATXN7L3(gene name)|psi-mi:ATXN7L3(display_short)|uniprotkb:SAGA-associated factor 11 homolog(gene name synonym) psi-mi:nadap_human(display_long)|uniprotkb:SLC4A1AP(gene name)|psi-mi:SLC4A1AP(display_short)|uniprotkb:Kidney anion exchanger adapter protein(gene name synonym)|uniprotkb:Solute carrier family 4 anion exchanger member 1 adapter protein(gene name synonym)|uniprotkb:Human lung cancer oncogene 3 protein(gene name synonym)|uniprotkb:HLC3(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476454|imex:IM-26985-229 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000087152(gene)|ensembl:ENST00000389384(transcript)|ensembl:ENST00000587097(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071819"(DUBm complex)|interpro:IPR013243(SCA7)|interpro:IPR013246(Sgf11, transcriptional regulation)|mint:Q14CW9|rcsb pdb:2KKT|reactome:R-HSA-3214847|refseq:NP_001092303.1|refseq:NP_064603.1|refseq:XP_016880374.1|refseq:XP_016880375.1 refseq:NP_060628.2|ensembl:ENSG00000163798(gene)|ensembl:ENST00000326019(transcript)|ensembl:ENST00000613058(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|mint:Q9BWU0|rcsb pdb:4H87 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:r0Yw6RIZ9DbDlu2xE5hOFPlvk849606 rogid:z28F2N7dfIFPIVaNMT0gb05iRNw9606 rigid:LUlPEhefrhE8rHVegUPgDgPA9Vk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14CW9 uniprotkb:P68363 intact:EBI-949215|ensembl:ENSP00000374035|ensembl:ENSP00000465614|uniprotkb:Q96N40|uniprotkb:Q9NPU5|uniprotkb:Q8IY68 intact:EBI-487083|intact:EBI-1384226|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:Q27I68|ensembl:ENSP00000336799|uniprotkb:Q8WU19 psi-mi:at7l3_human(display_long)|uniprotkb:ATXN7L3(gene name)|psi-mi:ATXN7L3(display_short)|uniprotkb:SAGA-associated factor 11 homolog(gene name synonym) psi-mi:tba1b_human(display_long)|uniprotkb:TUBA1B(gene name)|psi-mi:TUBA1B(display_short)|uniprotkb:Tubulin alpha-ubiquitous chain(gene name synonym)|uniprotkb:Alpha-tubulin ubiquitous(gene name synonym)|uniprotkb:Tubulin K-alpha-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476454|imex:IM-26985-229 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000087152(gene)|ensembl:ENST00000389384(transcript)|ensembl:ENST00000587097(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071819"(DUBm complex)|interpro:IPR013243(SCA7)|interpro:IPR013246(Sgf11, transcriptional regulation)|mint:Q14CW9|rcsb pdb:2KKT|reactome:R-HSA-3214847|refseq:NP_001092303.1|refseq:NP_064603.1|refseq:XP_016880374.1|refseq:XP_016880375.1 refseq:NP_006073.2|ensembl:ENSG00000123416(gene)|ensembl:ENST00000336023(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-983189|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|go:"GO:0045121"(membrane raft)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68363|rcsb pdb:2E4H|rcsb pdb:5IJ0|rcsb pdb:5IJ9|rcsb pdb:5N5N|rcsb pdb:6E7B|rcsb pdb:6E7C|rcsb pdb:6I2I|go:"GO:0051301"(cell division)|rcsb pdb:6J4V|rcsb pdb:6J8O|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|rcsb pdb:6S8L|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9013407|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-2132295|reactome:R-HSA-9668328 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:r0Yw6RIZ9DbDlu2xE5hOFPlvk849606 rogid:D4YpuLCXl/S+53qV7P7sF81aARY9606 rigid:LUlPEhefrhE8rHVegUPgDgPA9Vk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14CW9 uniprotkb:P51784 intact:EBI-949215|ensembl:ENSP00000374035|ensembl:ENSP00000465614|uniprotkb:Q96N40|uniprotkb:Q9NPU5|uniprotkb:Q8IY68 intact:EBI-306876|intact:EBI-1058416|uniprotkb:Q8IUG6|uniprotkb:Q9BWE1|uniprotkb:B2RTX1|ensembl:ENSP00000218348 psi-mi:at7l3_human(display_long)|uniprotkb:ATXN7L3(gene name)|psi-mi:ATXN7L3(display_short)|uniprotkb:SAGA-associated factor 11 homolog(gene name synonym) psi-mi:ubp11_human(display_long)|uniprotkb:USP11(gene name)|psi-mi:USP11(display_short)|uniprotkb:UHX1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 11(gene name synonym)|uniprotkb:Deubiquitinating enzyme 11(gene name synonym)|uniprotkb:Ubiquitin thioesterase 11(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476454|imex:IM-26985-229 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000087152(gene)|ensembl:ENST00000389384(transcript)|ensembl:ENST00000587097(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071819"(DUBm complex)|interpro:IPR013243(SCA7)|interpro:IPR013246(Sgf11, transcriptional regulation)|mint:Q14CW9|rcsb pdb:2KKT|reactome:R-HSA-3214847|refseq:NP_001092303.1|refseq:NP_064603.1|refseq:XP_016880374.1|refseq:XP_016880375.1 ensembl:ENSG00000102226(gene)|ensembl:ENST00000218348(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR029346|interpro:IPR035927|interpro:IPR038765|mint:P51784|rcsb pdb:4MEL|rcsb pdb:5OK6|reactome:R-HSA-390471|reactome:R-HSA-5689880|refseq:NP_004642.2|refseq:XP_011542290.1|refseq:XP_005272731.1|dip:DIP-27567N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:r0Yw6RIZ9DbDlu2xE5hOFPlvk849606 rogid:OSJLLFBf1ofw8SC01p2iiIM1oJo9606 rigid:LUlPEhefrhE8rHVegUPgDgPA9Vk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14CW9 uniprotkb:Q71DI3 intact:EBI-949215|ensembl:ENSP00000374035|ensembl:ENSP00000465614|uniprotkb:Q96N40|uniprotkb:Q9NPU5|uniprotkb:Q8IY68 intact:EBI-750650|uniprotkb:A2BDF6|uniprotkb:A6NFS4|uniprotkb:Q6B053|ensembl:ENSP00000333277|ensembl:ENSP00000358154|ensembl:ENSP00000385479 psi-mi:at7l3_human(display_long)|uniprotkb:ATXN7L3(gene name)|psi-mi:ATXN7L3(display_short)|uniprotkb:SAGA-associated factor 11 homolog(gene name synonym) psi-mi:h32_human(display_long)|uniprotkb:H3C13(gene name)|psi-mi:H3C13(display_short)|uniprotkb:H3C14(gene name)|psi-mi:H3C14(display_short)|uniprotkb:H3C15(gene name)|psi-mi:H3C15(display_short)|uniprotkb:H3-clustered histone 13(gene name synonym)|uniprotkb:H3-clustered histone 14(gene name synonym)|uniprotkb:H3-clustered histone 15(gene name synonym)|uniprotkb:H3F2(gene name synonym)|uniprotkb:H3FM(gene name synonym)|uniprotkb:HIST2H3A(gene name synonym)|uniprotkb:HIST2H3C(gene name synonym)|uniprotkb:HIST2H3D(gene name synonym)|uniprotkb:Histone H3/m(gene name synonym)|uniprotkb:Histone H3/o(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476454|imex:IM-26985-229 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000087152(gene)|ensembl:ENST00000389384(transcript)|ensembl:ENST00000587097(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071819"(DUBm complex)|interpro:IPR013243(SCA7)|interpro:IPR013246(Sgf11, transcriptional regulation)|mint:Q14CW9|rcsb pdb:2KKT|reactome:R-HSA-3214847|refseq:NP_001092303.1|refseq:NP_064603.1|refseq:XP_016880374.1|refseq:XP_016880375.1 refseq:NP_001005464.1|refseq:NP_001116847.1|refseq:NP_066403.2|dip:DIP-48606N|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|rcsb pdb:7BU9|rcsb pdb:7JO9|rcsb pdb:7JOA|reactome:R-HSA-3214858|reactome:R-HSA-3247509|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-983231|rcsb pdb:7JZV|reactome:R-HSA-1266695|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|ensembl:ENSG00000183598(gene)|ensembl:ENSG00000203811(gene)|ensembl:ENSG00000203852(gene)|ensembl:ENST00000331491(transcript)|ensembl:ENST00000369158(transcript)|ensembl:ENST00000403683(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:Q71DI3|rcsb pdb:2IIJ|rcsb pdb:2X4W|rcsb pdb:2X4X|rcsb pdb:2X4Y|rcsb pdb:3AV1|rcsb pdb:3DB3|rcsb pdb:3MO8|rcsb pdb:3QO2|rcsb pdb:3R93|rcsb pdb:4MZF|rcsb pdb:4MZG|rcsb pdb:4MZH|rcsb pdb:4OUC|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B40|rcsb pdb:5BO0|rcsb pdb:5CIU|rcsb pdb:5VAC|rcsb pdb:6ACE|rcsb pdb:6FML|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6Y5E|rcsb pdb:7BQZ - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:r0Yw6RIZ9DbDlu2xE5hOFPlvk849606 rogid:2TuVqWkeAnhHR4nrl0GNyUj1N3o9606 rigid:LUlPEhefrhE8rHVegUPgDgPA9Vk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14CW9 uniprotkb:Q9ULK2 intact:EBI-949215|ensembl:ENSP00000374035|ensembl:ENSP00000465614|uniprotkb:Q96N40|uniprotkb:Q9NPU5|uniprotkb:Q8IY68 intact:EBI-310660|ensembl:ENSP00000410759|uniprotkb:Q8N2T0|uniprotkb:A4D0Q2|uniprotkb:B4DTS1 psi-mi:at7l3_human(display_long)|uniprotkb:ATXN7L3(gene name)|psi-mi:ATXN7L3(display_short)|uniprotkb:SAGA-associated factor 11 homolog(gene name synonym) psi-mi:at7l1_human(display_long)|uniprotkb:ATXN7L1(gene name)|psi-mi:ATXN7L1(display_short)|uniprotkb:KIAA1218(gene name synonym)|uniprotkb:ATXN7L4(gene name synonym)|uniprotkb:Ataxin-7-like protein 4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476454|imex:IM-26985-229 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000087152(gene)|ensembl:ENST00000389384(transcript)|ensembl:ENST00000587097(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071819"(DUBm complex)|interpro:IPR013243(SCA7)|interpro:IPR013246(Sgf11, transcriptional regulation)|mint:Q14CW9|rcsb pdb:2KKT|reactome:R-HSA-3214847|refseq:NP_001092303.1|refseq:NP_064603.1|refseq:XP_016880374.1|refseq:XP_016880375.1 ensembl:ENSG00000146776(gene)|ensembl:ENST00000419735(transcript)|interpro:IPR013243(SCA7)|mint:Q9ULK2|refseq:NP_065776.1|refseq:NP_612504.1|refseq:NP_689962.1|ensembl:ENST00000318724|ensembl:ENSP00000326344|ensembl:ENSP00000410759|ensembl:ENST00000477775|ensembl:ENSP00000418476|refseq:XP_011514242.1|refseq:XP_011514256.1 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:r0Yw6RIZ9DbDlu2xE5hOFPlvk849606 rogid:oAY7Q/8MMAwsC4Ro7ocKmrBBIpA9606 rigid:LUlPEhefrhE8rHVegUPgDgPA9Vk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14CW9 uniprotkb:Q14197 intact:EBI-949215|ensembl:ENSP00000374035|ensembl:ENSP00000465614|uniprotkb:Q96N40|uniprotkb:Q9NPU5|uniprotkb:Q8IY68 intact:EBI-1049413|uniprotkb:Q53HM7|uniprotkb:Q53Y11|uniprotkb:B2RAD1|ensembl:ENSP00000301585 psi-mi:at7l3_human(display_long)|uniprotkb:ATXN7L3(gene name)|psi-mi:ATXN7L3(display_short)|uniprotkb:SAGA-associated factor 11 homolog(gene name synonym) psi-mi:ict1_human(display_long)|uniprotkb:Mitochondrial large ribosomal subunit protein mL62(gene name synonym)|uniprotkb:MRPL58(gene name)|psi-mi:MRPL58(display_short)|uniprotkb:39S ribosomal protein L58, mitochondrial(gene name synonym)|uniprotkb:DS1(gene name synonym)|uniprotkb:Digestion substraction 1(gene name synonym)|uniprotkb:ICT1(gene name synonym)|uniprotkb:Immature colon carcinoma transcript 1 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476454|imex:IM-26985-229 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000087152(gene)|ensembl:ENST00000389384(transcript)|ensembl:ENST00000587097(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071819"(DUBm complex)|interpro:IPR013243(SCA7)|interpro:IPR013246(Sgf11, transcriptional regulation)|mint:Q14CW9|rcsb pdb:2KKT|reactome:R-HSA-3214847|refseq:NP_001092303.1|refseq:NP_064603.1|refseq:XP_016880374.1|refseq:XP_016880375.1 refseq:NP_001536.1|refseq:NP_001290194.1|ensembl:ENSG00000167862(gene)|go:"GO:0004045"(aminoacyl-tRNA hydrolase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0016150"(translation release factor activity, codon nonspecific)|go:"GO:0070126"(mitochondrial translational termination)|interpro:IPR000352(Class I peptide chain release factor)|mint:Q14197|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7NQL|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENST00000301585(transcript) - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:r0Yw6RIZ9DbDlu2xE5hOFPlvk849606 rogid:7VHUOV/AvCr5g+TkvFNQqxp2kjM9606 rigid:LUlPEhefrhE8rHVegUPgDgPA9Vk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14CW9 uniprotkb:Q16594 intact:EBI-949215|ensembl:ENSP00000374035|ensembl:ENSP00000465614|uniprotkb:Q96N40|uniprotkb:Q9NPU5|uniprotkb:Q8IY68 intact:EBI-712521|ensembl:ENSP00000370193|ensembl:ENSP00000421873|ensembl:ENSP00000477611|ensembl:ENSP00000477750|ensembl:ENSP00000478935|ensembl:ENSP00000217893|uniprotkb:Q5U0D1|uniprotkb:Q9BTS1|uniprotkb:D3DWA3|intact:EBI-8645823|intact:MINT-8163548 psi-mi:at7l3_human(display_long)|uniprotkb:ATXN7L3(gene name)|psi-mi:ATXN7L3(display_short)|uniprotkb:SAGA-associated factor 11 homolog(gene name synonym) psi-mi:taf9_human(display_long)|uniprotkb:Transcription initiation factor TFIID 31 kDa subunit(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 32 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II TBP-associated factor subunit G(gene name synonym)|uniprotkb:STAF31/32(gene name synonym)|uniprotkb:TAF9(gene name)|psi-mi:TAF9(display_short)|uniprotkb:TAF2G(gene name synonym)|uniprotkb:TAFII31(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476454|imex:IM-26985-229 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000087152(gene)|ensembl:ENST00000389384(transcript)|ensembl:ENST00000587097(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071819"(DUBm complex)|interpro:IPR013243(SCA7)|interpro:IPR013246(Sgf11, transcriptional regulation)|mint:Q14CW9|rcsb pdb:2KKT|reactome:R-HSA-3214847|refseq:NP_001092303.1|refseq:NP_064603.1|refseq:XP_016880374.1|refseq:XP_016880375.1 ensembl:ENST00000217893(transcript)|ensembl:ENST00000328663(transcript)|ensembl:ENST00000506736(transcript)|ensembl:ENST00000615404(transcript)|ensembl:ENST00000616867(transcript)|ensembl:ENST00000617893(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000125"|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0030914"|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0070761"(pre-snoRNP complex)|go:"GO:0071339"(MLL1 complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|interpro:IPR003162(Transcription factor TAFII-31)|interpro:IPR009072(Histone-fold)|mint:Q16594|rcsb pdb:6F3T|rcsb pdb:6MZC|rcsb pdb:6MZD|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGF|rcsb pdb:7EGG|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-3214847|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-6807505|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|ensembl:ENSG00000273841(gene)|ensembl:ENSG00000276463(gene)|refseq:NP_001015892.1|refseq:NP_003178.1|dip:DIP-435N - - comment:"author score: 35" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:r0Yw6RIZ9DbDlu2xE5hOFPlvk849606 rogid:Drikn9IwpWQXbTTXGqwf1hlRNE09606 rigid:LUlPEhefrhE8rHVegUPgDgPA9Vk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14CW9 uniprotkb:Q9Y4A5 intact:EBI-949215|ensembl:ENSP00000374035|ensembl:ENSP00000465614|uniprotkb:Q96N40|uniprotkb:Q9NPU5|uniprotkb:Q8IY68 intact:EBI-399128|uniprotkb:O75218|uniprotkb:Q9Y631|uniprotkb:Q9Y6H4|uniprotkb:A4D265|ensembl:ENSP00000352925 psi-mi:at7l3_human(display_long)|uniprotkb:ATXN7L3(gene name)|psi-mi:ATXN7L3(display_short)|uniprotkb:SAGA-associated factor 11 homolog(gene name synonym) psi-mi:trrap_human(display_long)|uniprotkb:TRRAP(gene name)|psi-mi:TRRAP(display_short)|uniprotkb:PAF400(gene name synonym)|uniprotkb:350/400 kDa PCAF-associated factor(gene name synonym)|uniprotkb:STAF40(gene name synonym)|uniprotkb:Tra1 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476454|imex:IM-26985-229 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000087152(gene)|ensembl:ENST00000389384(transcript)|ensembl:ENST00000587097(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071819"(DUBm complex)|interpro:IPR013243(SCA7)|interpro:IPR013246(Sgf11, transcriptional regulation)|mint:Q14CW9|rcsb pdb:2KKT|reactome:R-HSA-3214847|refseq:NP_001092303.1|refseq:NP_064603.1|refseq:XP_016880374.1|refseq:XP_016880375.1 refseq:NP_003487.1|ensembl:ENSG00000196367(gene)|ensembl:ENST00000359863(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000125"|go:"GO:0000812"(Swr1 complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006281"(DNA repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016310"(phosphorylation)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033317|mint:Q9Y4A5|reactome:R-HSA-201722|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_001231509.1|dip:DIP-28149N - - comment:"author score: 41" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:r0Yw6RIZ9DbDlu2xE5hOFPlvk849606 rogid:bGoQLXxMT0zZ0jVW+2s4hUwnBA49606 rigid:LUlPEhefrhE8rHVegUPgDgPA9Vk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14CW9 uniprotkb:Q5T6C5 intact:EBI-949215|ensembl:ENSP00000374035|ensembl:ENSP00000465614|uniprotkb:Q96N40|uniprotkb:Q9NPU5|uniprotkb:Q8IY68 intact:EBI-949168|ensembl:ENSP00000358886 psi-mi:at7l3_human(display_long)|uniprotkb:ATXN7L3(gene name)|psi-mi:ATXN7L3(display_short)|uniprotkb:SAGA-associated factor 11 homolog(gene name synonym) psi-mi:at7l2_human(display_long)|uniprotkb:ATXN7L2(gene name)|psi-mi:ATXN7L2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476454|imex:IM-26985-229 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000087152(gene)|ensembl:ENST00000389384(transcript)|ensembl:ENST00000587097(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071819"(DUBm complex)|interpro:IPR013243(SCA7)|interpro:IPR013246(Sgf11, transcriptional regulation)|mint:Q14CW9|rcsb pdb:2KKT|reactome:R-HSA-3214847|refseq:NP_001092303.1|refseq:NP_064603.1|refseq:XP_016880374.1|refseq:XP_016880375.1 ensembl:ENSG00000162650(gene)|ensembl:ENST00000369870(transcript)|interpro:IPR013243(SCA7)|mint:Q5T6C5|refseq:NP_699171.3 - - comment:"author score: 41" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:r0Yw6RIZ9DbDlu2xE5hOFPlvk849606 rogid:kPIjJ2NIDAAHLvVnRNzSD61XZD89606 rigid:LUlPEhefrhE8rHVegUPgDgPA9Vk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14CW9 uniprotkb:O75486 intact:EBI-949215|ensembl:ENSP00000374035|ensembl:ENSP00000465614|uniprotkb:Q96N40|uniprotkb:Q9NPU5|uniprotkb:Q8IY68 intact:EBI-896640|uniprotkb:A6NKG9|uniprotkb:O76066|uniprotkb:Q5TAV9|uniprotkb:B2R9Q5|uniprotkb:Q86VN7|intact:EBI-11061133|ensembl:ENSP00000360514|ensembl:ENSP00000436411 psi-mi:at7l3_human(display_long)|uniprotkb:ATXN7L3(gene name)|psi-mi:ATXN7L3(display_short)|uniprotkb:SAGA-associated factor 11 homolog(gene name synonym) psi-mi:supt3_human(display_long)|uniprotkb:SUPT3H(gene name)|psi-mi:SUPT3H(display_short)|uniprotkb:SPT3(gene name synonym)|uniprotkb:SPT3-like protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476454|imex:IM-26985-229 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000087152(gene)|ensembl:ENST00000389384(transcript)|ensembl:ENST00000587097(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071819"(DUBm complex)|interpro:IPR013243(SCA7)|interpro:IPR013246(Sgf11, transcriptional regulation)|mint:Q14CW9|rcsb pdb:2KKT|reactome:R-HSA-3214847|refseq:NP_001092303.1|refseq:NP_064603.1|refseq:XP_016880374.1|refseq:XP_016880375.1 refseq:XP_016866861.1|refseq:NP_003590.1|refseq:NP_852001.1|refseq:XP_016866860.1|dip:DIP-28148N|ensembl:ENSG00000196284(gene)|ensembl:ENST00000371459(transcript)|ensembl:ENST00000475057(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003195(Transcription initiation factor IID, 18 kDa subunit)|interpro:IPR009072(Histone-fold)|mint:O75486|reactome:R-HSA-3214847 - - comment:"author score: 42" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:r0Yw6RIZ9DbDlu2xE5hOFPlvk849606 rogid:P+62Ufs6GyoQYKCpbNaab5KzYOc9606 rigid:LUlPEhefrhE8rHVegUPgDgPA9Vk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14CW9 uniprotkb:O75528 intact:EBI-949215|ensembl:ENSP00000374035|ensembl:ENSP00000465614|uniprotkb:Q96N40|uniprotkb:Q9NPU5|uniprotkb:Q8IY68 intact:EBI-473249|uniprotkb:Q9UFS2|intact:EBI-28973289|ensembl:ENSP00000307684|ensembl:ENSP00000393471|uniprotkb:Q6FI83 psi-mi:at7l3_human(display_long)|uniprotkb:ATXN7L3(gene name)|psi-mi:ATXN7L3(display_short)|uniprotkb:SAGA-associated factor 11 homolog(gene name synonym) psi-mi:tada3_human(display_long)|uniprotkb:ADA3 homolog(gene name synonym)|uniprotkb:STAF54(gene name synonym)|uniprotkb:TADA3(gene name)|psi-mi:TADA3(display_short)|uniprotkb:ADA3(gene name synonym)|uniprotkb:TADA3L(gene name synonym)|uniprotkb:Transcriptional adapter 3-like(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476454|imex:IM-26985-229 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000087152(gene)|ensembl:ENST00000389384(transcript)|ensembl:ENST00000587097(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071819"(DUBm complex)|interpro:IPR013243(SCA7)|interpro:IPR013246(Sgf11, transcriptional regulation)|mint:Q14CW9|rcsb pdb:2KKT|reactome:R-HSA-3214847|refseq:NP_001092303.1|refseq:NP_064603.1|refseq:XP_016880374.1|refseq:XP_016880375.1 ensembl:ENSG00000171148(gene)|ensembl:ENST00000301964(transcript)|ensembl:ENST00000440161(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030914"|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR019340|mint:O75528|reactome:R-HSA-3214847|reactome:R-HSA-5689880|ensembl:ENSP00000307684|ensembl:ENST00000343450|ensembl:ENSP00000343649|ensembl:ENSP00000393471|refseq:NP_006345.1|refseq:NP_597814.1|refseq:NP_001265199.1 - - comment:"author score: 52" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:r0Yw6RIZ9DbDlu2xE5hOFPlvk849606 rogid:5NQkQiw+G/8uL2fjoMgW8+mTB8o9606 rigid:LUlPEhefrhE8rHVegUPgDgPA9Vk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14CW9 uniprotkb:Q92831 intact:EBI-949215|ensembl:ENSP00000374035|ensembl:ENSP00000465614|uniprotkb:Q96N40|uniprotkb:Q9NPU5|uniprotkb:Q8IY68 intact:EBI-477430|uniprotkb:Q6NSK1|ensembl:ENSP00000263754 psi-mi:at7l3_human(display_long)|uniprotkb:ATXN7L3(gene name)|psi-mi:ATXN7L3(display_short)|uniprotkb:SAGA-associated factor 11 homolog(gene name synonym) psi-mi:kat2b_human(display_long)|uniprotkb:P300/CBP-associated factor(gene name synonym)|uniprotkb:PCAF(gene name synonym)|uniprotkb:Lysine acetyltransferase 2B(gene name synonym)|uniprotkb:Histone acetyltransferase PCAF(gene name synonym)|uniprotkb:KAT2B(gene name)|psi-mi:KAT2B(display_short)|uniprotkb:Spermidine acetyltransferase KAT2B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476454|imex:IM-26985-229 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000087152(gene)|ensembl:ENST00000389384(transcript)|ensembl:ENST00000587097(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071819"(DUBm complex)|interpro:IPR013243(SCA7)|interpro:IPR013246(Sgf11, transcriptional regulation)|mint:Q14CW9|rcsb pdb:2KKT|reactome:R-HSA-3214847|refseq:NP_001092303.1|refseq:NP_064603.1|refseq:XP_016880374.1|refseq:XP_016880375.1 ensembl:ENSG00000114166(gene)|ensembl:ENST00000263754(transcript)|go:"GO:0000125"|go:"GO:0000776"(kinetochore)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004145"(diamine N-acetyltransferase activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006473"(protein acetylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031672"(A band)|go:"GO:0031674"(I band)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|refseq:NP_003875.3|go:"GO:0043970"(histone H3-K9 acetylation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060173"(limb development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:2000233"(negative regulation of rRNA processing)|interpro:IPR000182(GCN5-related N-acetyltransferase)|go:"GO:0043966"(histone H3 acetylation)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|go:"GO:0042826"(histone deacetylase binding)|interpro:IPR036427|interpro:IPR037800|mint:Q92831|rcsb pdb:1CM0|rcsb pdb:1JM4|rcsb pdb:1N72|rcsb pdb:1WUG|rcsb pdb:1WUM|rcsb pdb:1ZS5|rcsb pdb:2RNW|rcsb pdb:2RNX|rcsb pdb:3GG3|rcsb pdb:4NSQ|rcsb pdb:5FDZ|rcsb pdb:5FE0|rcsb pdb:5FE1|rcsb pdb:5FE2|rcsb pdb:5FE3|rcsb pdb:5FE4|rcsb pdb:5FE5|rcsb pdb:5FE6|rcsb pdb:5FE7|rcsb pdb:5FE8|rcsb pdb:5FE9|rcsb pdb:5LVQ|rcsb pdb:5LVR|rcsb pdb:5MKX|rcsb pdb:6J3O|reactome:R-HSA-1912408|reactome:R-HSA-2032785|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214847|reactome:R-HSA-350054|reactome:R-HSA-5250924|reactome:R-HSA-5578768|reactome:R-HSA-5689901|reactome:R-HSA-73762|reactome:R-HSA-8936459|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9018519|reactome:R-HSA-9617629|dip:DIP-29778N - - comment:"author score: 54" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:r0Yw6RIZ9DbDlu2xE5hOFPlvk849606 rogid:g0Gzr/F28rlhpv1qBl+kMEuwlZI9606 rigid:LUlPEhefrhE8rHVegUPgDgPA9Vk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14CW9 uniprotkb:Q8NEM7 intact:EBI-949215|ensembl:ENSP00000374035|ensembl:ENSP00000465614|uniprotkb:Q96N40|uniprotkb:Q9NPU5|uniprotkb:Q8IY68 intact:EBI-946984|uniprotkb:Q71RF3|uniprotkb:Q9Y6A6|ensembl:ENSP00000218894|uniprotkb:E7ER46 psi-mi:at7l3_human(display_long)|uniprotkb:ATXN7L3(gene name)|psi-mi:ATXN7L3(display_short)|uniprotkb:SAGA-associated factor 11 homolog(gene name synonym) psi-mi:sp20h_human(display_long)|uniprotkb:SUPT20H(gene name)|psi-mi:SUPT20H(display_short)|uniprotkb:C13orf19(gene name synonym)|uniprotkb:FAM48A(gene name synonym)|uniprotkb:p38-interacting protein(gene name synonym)|uniprotkb:FP757(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476454|imex:IM-26985-229 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000087152(gene)|ensembl:ENST00000389384(transcript)|ensembl:ENST00000587097(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071819"(DUBm complex)|interpro:IPR013243(SCA7)|interpro:IPR013246(Sgf11, transcriptional regulation)|mint:Q14CW9|rcsb pdb:2KKT|reactome:R-HSA-3214847|refseq:NP_001092303.1|refseq:NP_064603.1|refseq:XP_016880374.1|refseq:XP_016880375.1 refseq:NP_001265409.1|refseq:NP_001265410.1|refseq:NP_001265411.1|refseq:NP_001014308.2|refseq:NP_060039.1|ensembl:ENSG00000102710(gene)|ensembl:ENST00000350612(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006914"(autophagy)|go:"GO:0007369"(gastrulation)|go:"GO:0070461"(SAGA-type complex)|interpro:IPR021950|mint:Q8NEM7|reactome:R-HSA-3214847 - - comment:"author score: 55" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:r0Yw6RIZ9DbDlu2xE5hOFPlvk849606 rogid:7s9ChKIewCopRWC7otwhnH6hYEs9606 rigid:LUlPEhefrhE8rHVegUPgDgPA9Vk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14CW9 uniprotkb:Q9HBM6 intact:EBI-949215|ensembl:ENSP00000374035|ensembl:ENSP00000465614|uniprotkb:Q96N40|uniprotkb:Q9NPU5|uniprotkb:Q8IY68 intact:EBI-751601|uniprotkb:Q9Y2S3|uniprotkb:B2RUZ9|ensembl:ENSP00000339917 psi-mi:at7l3_human(display_long)|uniprotkb:ATXN7L3(gene name)|psi-mi:ATXN7L3(display_short)|uniprotkb:SAGA-associated factor 11 homolog(gene name synonym) psi-mi:taf9b_human(display_long)|uniprotkb:Transcription initiation factor TFIID subunit 9-like(gene name synonym)|uniprotkb:Transcription-associated factor TAFII31L(gene name synonym)|uniprotkb:Neuronal cell death-related protein 7(gene name synonym)|uniprotkb:TAF9B(gene name)|psi-mi:TAF9B(display_short)|uniprotkb:TAF9L(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476454|imex:IM-26985-229 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000087152(gene)|ensembl:ENST00000389384(transcript)|ensembl:ENST00000587097(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071819"(DUBm complex)|interpro:IPR013243(SCA7)|interpro:IPR013246(Sgf11, transcriptional regulation)|mint:Q14CW9|rcsb pdb:2KKT|reactome:R-HSA-3214847|refseq:NP_001092303.1|refseq:NP_064603.1|refseq:XP_016880374.1|refseq:XP_016880375.1 refseq:NP_057059.2|ensembl:ENSG00000187325(gene)|ensembl:ENST00000341864(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|interpro:IPR003162(Transcription factor TAFII-31)|interpro:IPR009072(Histone-fold)|mint:Q9HBM6|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-5689880|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042 - - comment:"author score: 55" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:r0Yw6RIZ9DbDlu2xE5hOFPlvk849606 rogid:8+i5lmcx4OcgCEbk2F9MS8bYhos9606 rigid:LUlPEhefrhE8rHVegUPgDgPA9Vk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14CW9 uniprotkb:Q86TJ2 intact:EBI-949215|ensembl:ENSP00000374035|ensembl:ENSP00000465614|uniprotkb:Q96N40|uniprotkb:Q9NPU5|uniprotkb:Q8IY68 intact:EBI-2512219|uniprotkb:Q6MZG9|uniprotkb:B3KSN0|uniprotkb:B3KU86|uniprotkb:A4QMR7|uniprotkb:A0AUJ8|ensembl:ENSP00000308022 psi-mi:at7l3_human(display_long)|uniprotkb:ATXN7L3(gene name)|psi-mi:ATXN7L3(display_short)|uniprotkb:SAGA-associated factor 11 homolog(gene name synonym) psi-mi:tad2b_human(display_long)|uniprotkb:TADA2B(gene name)|psi-mi:TADA2B(display_short)|uniprotkb:ADA2B(gene name synonym)|uniprotkb:ADA2-like protein beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476454|imex:IM-26985-229 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000087152(gene)|ensembl:ENST00000389384(transcript)|ensembl:ENST00000587097(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071819"(DUBm complex)|interpro:IPR013243(SCA7)|interpro:IPR013246(Sgf11, transcriptional regulation)|mint:Q14CW9|rcsb pdb:2KKT|reactome:R-HSA-3214847|refseq:NP_001092303.1|refseq:NP_064603.1|refseq:XP_016880374.1|refseq:XP_016880375.1 refseq:XP_011511897.1|refseq:NP_689506.2|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|mint:Q86TJ2|reactome:R-HSA-3214847|reactome:R-HSA-5689880|interpro:IPR009057(Homeodomain-like)|ensembl:ENSG00000173011(gene)|ensembl:ENST00000310074(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030914"|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0070461"(SAGA-type complex)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding) - - comment:"author score: 67" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:r0Yw6RIZ9DbDlu2xE5hOFPlvk849606 rogid:ShA8/bknqf6XcaEWL3YFWOz9s9c9606 rigid:LUlPEhefrhE8rHVegUPgDgPA9Vk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14CW9 uniprotkb:O94864 intact:EBI-949215|ensembl:ENSP00000374035|ensembl:ENSP00000465614|uniprotkb:Q96N40|uniprotkb:Q9NPU5|uniprotkb:Q8IY68 intact:EBI-722912|uniprotkb:Q6IB21|uniprotkb:Q9H2T6|uniprotkb:B4E3W3|ensembl:ENSP00000336750 psi-mi:at7l3_human(display_long)|uniprotkb:ATXN7L3(gene name)|psi-mi:ATXN7L3(display_short)|uniprotkb:SAGA-associated factor 11 homolog(gene name synonym) psi-mi:st65g_human(display_long)|uniprotkb:SPTF-associated factor 65 gamma(gene name synonym)|uniprotkb:Suppressor of Ty 7-like(gene name synonym)|uniprotkb:Adenocarcinoma antigen ART1(gene name synonym)|uniprotkb:SUPT7L(gene name)|psi-mi:SUPT7L(display_short)|uniprotkb:KIAA0764(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476454|imex:IM-26985-229 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000087152(gene)|ensembl:ENST00000389384(transcript)|ensembl:ENST00000587097(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071819"(DUBm complex)|interpro:IPR013243(SCA7)|interpro:IPR013246(Sgf11, transcriptional regulation)|mint:Q14CW9|rcsb pdb:2KKT|reactome:R-HSA-3214847|refseq:NP_001092303.1|refseq:NP_064603.1|refseq:XP_016880374.1|refseq:XP_016880375.1 refseq:NP_001269658.1|refseq:NP_001269659.1|refseq:NP_001269660.1|refseq:NP_001269661.1|refseq:NP_055675.1|refseq:XP_005264729.1|ensembl:ENSG00000119760(gene)|ensembl:ENST00000337768(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0030914"|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|interpro:IPR006565(Bromodomain transcription factor)|interpro:IPR009072(Histone-fold)|interpro:IPR039460|mint:O94864|reactome:R-HSA-3214847 - - comment:"author score: 68" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:r0Yw6RIZ9DbDlu2xE5hOFPlvk849606 rogid:v26YjDoNB/9ekC4xRZEm77Roruw9606 rigid:LUlPEhefrhE8rHVegUPgDgPA9Vk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14CW9 uniprotkb:Q96BN2 intact:EBI-949215|ensembl:ENSP00000374035|ensembl:ENSP00000465614|uniprotkb:Q96N40|uniprotkb:Q9NPU5|uniprotkb:Q8IY68 intact:EBI-2512236|ensembl:ENSP00000356848|uniprotkb:A8K4J9 psi-mi:at7l3_human(display_long)|uniprotkb:ATXN7L3(gene name)|psi-mi:ATXN7L3(display_short)|uniprotkb:SAGA-associated factor 11 homolog(gene name synonym) psi-mi:tada1_human(display_long)|uniprotkb:TADA1(gene name)|psi-mi:TADA1(display_short)|uniprotkb:TADA1L(gene name synonym)|uniprotkb:Transcriptional adapter 1-like protein(gene name synonym)|uniprotkb:SPT3-associated factor 42(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476454|imex:IM-26985-229 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000087152(gene)|ensembl:ENST00000389384(transcript)|ensembl:ENST00000587097(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071819"(DUBm complex)|interpro:IPR013243(SCA7)|interpro:IPR013246(Sgf11, transcriptional regulation)|mint:Q14CW9|rcsb pdb:2KKT|reactome:R-HSA-3214847|refseq:NP_001092303.1|refseq:NP_064603.1|refseq:XP_016880374.1|refseq:XP_016880375.1 ensembl:ENSG00000152382(gene)|ensembl:ENST00000367874(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030914"|go:"GO:0043966"(histone H3 acetylation)|interpro:IPR024738|mint:Q96BN2|reactome:R-HSA-3214847|refseq:NP_444281.1 - - comment:"author score: 72" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:r0Yw6RIZ9DbDlu2xE5hOFPlvk849606 rogid:07aGEsEjtD884LVJ6Jlj12+TdK49606 rigid:LUlPEhefrhE8rHVegUPgDgPA9Vk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14CW9 uniprotkb:Q70EK9 intact:EBI-949215|ensembl:ENSP00000374035|ensembl:ENSP00000465614|uniprotkb:Q96N40|uniprotkb:Q9NPU5|uniprotkb:Q8IY68 intact:EBI-14405234|ensembl:ENSP00000423333|uniprotkb:Q8IWJ8 psi-mi:at7l3_human(display_long)|uniprotkb:ATXN7L3(gene name)|psi-mi:ATXN7L3(display_short)|uniprotkb:SAGA-associated factor 11 homolog(gene name synonym) psi-mi:ubp51_human(display_long)|uniprotkb:USP51(gene name)|psi-mi:USP51(display_short)|uniprotkb:Deubiquitinating enzyme 51(gene name synonym)|uniprotkb:Ubiquitin thioesterase 51(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 51(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476454|imex:IM-26985-229 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000087152(gene)|ensembl:ENST00000389384(transcript)|ensembl:ENST00000587097(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071819"(DUBm complex)|interpro:IPR013243(SCA7)|interpro:IPR013246(Sgf11, transcriptional regulation)|mint:Q14CW9|rcsb pdb:2KKT|reactome:R-HSA-3214847|refseq:NP_001092303.1|refseq:NP_064603.1|refseq:XP_016880374.1|refseq:XP_016880375.1 interpro:IPR038765|mint:Q70EK9|ensembl:ENSG00000247746(gene)|ensembl:ENST00000500968(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005694"(chromosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0042393"(histone binding)|go:"GO:2001020"(regulation of response to DNA damage stimulus)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001607(Zinc finger, UBP-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018200|interpro:IPR028889|interpro:IPR033383|refseq:NP_958443.1|refseq:XP_016884788.1|refseq:XP_016884789.1|refseq:XP_016884790.1 - - comment:"author score: 74" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:r0Yw6RIZ9DbDlu2xE5hOFPlvk849606 rogid:W9XXkq7CKWSVoSztbvO+0UVSKt89606 rigid:LUlPEhefrhE8rHVegUPgDgPA9Vk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14CW9 uniprotkb:A6NNY8 intact:EBI-949215|ensembl:ENSP00000374035|ensembl:ENSP00000465614|uniprotkb:Q96N40|uniprotkb:Q9NPU5|uniprotkb:Q8IY68 intact:EBI-2512262|intact:EBI-28988282|ensembl:ENSP00000483631 psi-mi:at7l3_human(display_long)|uniprotkb:ATXN7L3(gene name)|psi-mi:ATXN7L3(display_short)|uniprotkb:SAGA-associated factor 11 homolog(gene name synonym) psi-mi:ubp27_human(display_long)|uniprotkb:USP27X(gene name)|psi-mi:USP27X(display_short)|uniprotkb:USP22L(gene name synonym)|uniprotkb:USP27(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 27(gene name synonym)|uniprotkb:Deubiquitinating enzyme 27(gene name synonym)|uniprotkb:X-linked ubiquitin carboxyl-terminal hydrolase 27(gene name synonym)|uniprotkb:Ubiquitin carboxyl-terminal hydrolase 22-like(gene name synonym)|uniprotkb:Ubiquitin thioesterase 27(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476454|imex:IM-26985-229 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000087152(gene)|ensembl:ENST00000389384(transcript)|ensembl:ENST00000587097(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071819"(DUBm complex)|interpro:IPR013243(SCA7)|interpro:IPR013246(Sgf11, transcriptional regulation)|mint:Q14CW9|rcsb pdb:2KKT|reactome:R-HSA-3214847|refseq:NP_001092303.1|refseq:NP_064603.1|refseq:XP_016880374.1|refseq:XP_016880375.1 ensembl:ENSG00000273820(gene)|ensembl:ENST00000621775(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0050821"(protein stabilization)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765|mint:A6NNY8|refseq:NP_001138545.1|ensembl:ENSP00000483631 - - comment:"author score: 75" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:r0Yw6RIZ9DbDlu2xE5hOFPlvk849606 rogid:8a2mLpB/MpBNttLlpgcl9dTQz/M9606 rigid:LUlPEhefrhE8rHVegUPgDgPA9Vk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14CW9 uniprotkb:O75529 intact:EBI-949215|ensembl:ENSP00000374035|ensembl:ENSP00000465614|uniprotkb:Q96N40|uniprotkb:Q9NPU5|uniprotkb:Q8IY68 intact:EBI-1785876|uniprotkb:Q8IW31|uniprotkb:Q5TDI6|uniprotkb:Q5TDI5|ensembl:ENSP00000258281 psi-mi:at7l3_human(display_long)|uniprotkb:ATXN7L3(gene name)|psi-mi:ATXN7L3(display_short)|uniprotkb:SAGA-associated factor 11 homolog(gene name synonym) psi-mi:taf5l_human(display_long)|uniprotkb:TAF5L(gene name)|psi-mi:TAF5L(display_short)|uniprotkb:PAF65B(gene name synonym)|uniprotkb:PCAF-associated factor 65 beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476454|imex:IM-26985-229 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000087152(gene)|ensembl:ENST00000389384(transcript)|ensembl:ENST00000587097(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071819"(DUBm complex)|interpro:IPR013243(SCA7)|interpro:IPR013246(Sgf11, transcriptional regulation)|mint:Q14CW9|rcsb pdb:2KKT|reactome:R-HSA-3214847|refseq:NP_001092303.1|refseq:NP_064603.1|refseq:XP_016880374.1|refseq:XP_016880375.1 refseq:NP_001020418.1|refseq:NP_055224.1|refseq:XP_005273156.1|dip:DIP-28147N|ensembl:ENSG00000135801(gene)|ensembl:ENST00000258281(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016607"(nuclear speck)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:1904672"(regulation of somatic stem cell population maintenance)|interpro:IPR001680(WD40 repeat)|interpro:IPR007582(WD40 associated region in TFIID subunit)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037264|interpro:IPR037783|interpro:IPR037826|mint:O75529|reactome:R-HSA-3214847 - - comment:"author score: 76" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:r0Yw6RIZ9DbDlu2xE5hOFPlvk849606 rogid:3D2y64CWMvwok3BvV2CpH6iX84E9606 rigid:LUlPEhefrhE8rHVegUPgDgPA9Vk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14CW9 uniprotkb:Q9Y6J9 intact:EBI-949215|ensembl:ENSP00000374035|ensembl:ENSP00000465614|uniprotkb:Q96N40|uniprotkb:Q9NPU5|uniprotkb:Q8IY68 intact:EBI-743984|uniprotkb:Q96HA6|uniprotkb:B2RAT0|ensembl:ENSP00000294168 psi-mi:at7l3_human(display_long)|uniprotkb:ATXN7L3(gene name)|psi-mi:ATXN7L3(display_short)|uniprotkb:SAGA-associated factor 11 homolog(gene name synonym) psi-mi:taf6l_human(display_long)|uniprotkb:PCAF-associated factor 65-alpha(gene name synonym)|uniprotkb:TAF6L(gene name)|psi-mi:TAF6L(display_short)|uniprotkb:PAF65A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476454|imex:IM-26985-229 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000087152(gene)|ensembl:ENST00000389384(transcript)|ensembl:ENST00000587097(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071819"(DUBm complex)|interpro:IPR013243(SCA7)|interpro:IPR013246(Sgf11, transcriptional regulation)|mint:Q14CW9|rcsb pdb:2KKT|reactome:R-HSA-3214847|refseq:NP_001092303.1|refseq:NP_064603.1|refseq:XP_016880374.1|refseq:XP_016880375.1 refseq:NP_006464.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0030914"|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904672"(regulation of somatic stem cell population maintenance)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|interpro:IPR009072(Histone-fold)|interpro:IPR011442(Protein of unknown function DUF1546)|interpro:IPR037796|mint:Q9Y6J9|reactome:R-HSA-3214847|ensembl:ENSG00000162227(gene)|ensembl:ENST00000294168(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000124"(SAGA complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated) - - comment:"author score: 86" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:r0Yw6RIZ9DbDlu2xE5hOFPlvk849606 rogid:ZcrK24blWTsAkCgruDbSiUflbtA9606 rigid:LUlPEhefrhE8rHVegUPgDgPA9Vk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14CW9 uniprotkb:Q9UPT9 intact:EBI-949215|ensembl:ENSP00000374035|ensembl:ENSP00000465614|uniprotkb:Q96N40|uniprotkb:Q9NPU5|uniprotkb:Q8IY68 intact:EBI-723510|ensembl:ENSP00000261497|uniprotkb:A0JNS3|uniprotkb:Q2NLE2|uniprotkb:Q6MZY4|uniprotkb:Q8TBS8|uniprotkb:Q96IW5 psi-mi:at7l3_human(display_long)|uniprotkb:ATXN7L3(gene name)|psi-mi:ATXN7L3(display_short)|uniprotkb:SAGA-associated factor 11 homolog(gene name synonym) psi-mi:ubp22_human(display_long)|uniprotkb:Ubiquitin-specific-processing protease 22(gene name synonym)|uniprotkb:Deubiquitinating enzyme 22(gene name synonym)|uniprotkb:USP22(gene name)|psi-mi:USP22(display_short)|uniprotkb:KIAA1063(gene name synonym)|uniprotkb:USP3L(gene name synonym)|uniprotkb:Ubiquitin thioesterase 22(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476454|imex:IM-26985-229 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000087152(gene)|ensembl:ENST00000389384(transcript)|ensembl:ENST00000587097(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071819"(DUBm complex)|interpro:IPR013243(SCA7)|interpro:IPR013246(Sgf11, transcriptional regulation)|mint:Q14CW9|rcsb pdb:2KKT|reactome:R-HSA-3214847|refseq:NP_001092303.1|refseq:NP_064603.1|refseq:XP_016880374.1|refseq:XP_016880375.1 refseq:NP_056091.1|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018200|go:"GO:0007049"(cell cycle)|interpro:IPR028889|interpro:IPR038765|mint:Q9UPT9|go:"GO:0008270"(zinc ion binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|reactome:R-HSA-3214847|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019899"(enzyme binding)|reactome:R-HSA-5689880|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001607(Zinc finger, UBP-type)|ensembl:ENSG00000124422(gene)|ensembl:ENST00000261497(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process) - - comment:"author score: 141" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:r0Yw6RIZ9DbDlu2xE5hOFPlvk849606 rogid:8n1lOTC7I8dP3RY1IEUtIkJiSXc9606 rigid:LUlPEhefrhE8rHVegUPgDgPA9Vk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14CW9 uniprotkb:Q9NPA8 intact:EBI-949215|ensembl:ENSP00000374035|ensembl:ENSP00000465614|uniprotkb:Q96N40|uniprotkb:Q9NPU5|uniprotkb:Q8IY68 intact:EBI-719226|uniprotkb:B2RE52|intact:EBI-10972054|uniprotkb:G3V117|ensembl:ENSP00000429986 psi-mi:at7l3_human(display_long)|uniprotkb:ATXN7L3(gene name)|psi-mi:ATXN7L3(display_short)|uniprotkb:SAGA-associated factor 11 homolog(gene name synonym) psi-mi:eny2_human(display_long)|uniprotkb:Enhancer of yellow 2 transcription factor homolog(gene name synonym)|uniprotkb:DC6(orf name)|uniprotkb:ENY2(gene name)|psi-mi:ENY2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476454|imex:IM-26985-229 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000087152(gene)|ensembl:ENST00000389384(transcript)|ensembl:ENST00000587097(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071819"(DUBm complex)|interpro:IPR013243(SCA7)|interpro:IPR013246(Sgf11, transcriptional regulation)|mint:Q14CW9|rcsb pdb:2KKT|reactome:R-HSA-3214847|refseq:NP_001092303.1|refseq:NP_064603.1|refseq:XP_016880374.1|refseq:XP_016880375.1 refseq:NP_001180486.1|refseq:NP_064574.1|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0061179"(negative regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071819"(DUBm complex)|interpro:IPR018783|interpro:IPR038212|mint:Q9NPA8|rcsb pdb:4DHX|go:"GO:0030374"(nuclear receptor coactivator activity)|reactome:R-HSA-3214847|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0015031"(protein transport)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|ensembl:ENSG00000120533(gene)|ensembl:ENST00000521688(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II) - - comment:"author score: 146" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:r0Yw6RIZ9DbDlu2xE5hOFPlvk849606 rogid:CJmjqxLqgpxrqtvVVFcgxW5nloE9606 rigid:LUlPEhefrhE8rHVegUPgDgPA9Vk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9ULK2 uniprotkb:Q5I0X7 intact:EBI-310660|ensembl:ENSP00000410759|uniprotkb:Q8N2T0|uniprotkb:A4D0Q2|uniprotkb:B4DTS1 intact:EBI-8636434|ensembl:ENSP00000333018|intact:MINT-8162555 psi-mi:at7l1_human(display_long)|uniprotkb:ATXN7L1(gene name)|psi-mi:ATXN7L1(display_short)|uniprotkb:KIAA1218(gene name synonym)|uniprotkb:ATXN7L4(gene name synonym)|uniprotkb:Ataxin-7-like protein 4(gene name synonym) psi-mi:ttc32_human(display_long)|uniprotkb:TTC32(gene name)|psi-mi:TTC32(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476424|imex:IM-26985-385 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000146776(gene)|ensembl:ENST00000419735(transcript)|interpro:IPR013243(SCA7)|mint:Q9ULK2|refseq:NP_065776.1|refseq:NP_612504.1|refseq:NP_689962.1|ensembl:ENST00000318724|ensembl:ENSP00000326344|ensembl:ENSP00000410759|ensembl:ENST00000477775|ensembl:ENSP00000418476|refseq:XP_011514242.1|refseq:XP_011514256.1 ensembl:ENSG00000183891(gene)|ensembl:ENST00000333610(transcript)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q5I0X7|refseq:NP_001008238.1 - - comment:mint|comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:oAY7Q/8MMAwsC4Ro7ocKmrBBIpA9606 rogid:I1iIVeaECGgtkP8/DPYF/SpCt3Q9606 rigid:YvhwMmfVv5EzR+s9je2yAGEhKQ4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9ULK2 uniprotkb:Q9H9T3 intact:EBI-310660|ensembl:ENSP00000410759|uniprotkb:Q8N2T0|uniprotkb:A4D0Q2|uniprotkb:B4DTS1 intact:EBI-355217|uniprotkb:B4DE19|uniprotkb:B4DIG1|uniprotkb:E2QRI5|uniprotkb:Q53G84|uniprotkb:Q6AWB0|uniprotkb:Q9BVF7|uniprotkb:Q9NVZ1|ensembl:ENSP00000256398 psi-mi:at7l1_human(display_long)|uniprotkb:ATXN7L1(gene name)|psi-mi:ATXN7L1(display_short)|uniprotkb:KIAA1218(gene name synonym)|uniprotkb:ATXN7L4(gene name synonym)|uniprotkb:Ataxin-7-like protein 4(gene name synonym) psi-mi:elp3_human(display_long)|uniprotkb:ELP3(gene name)|psi-mi:ELP3(display_short)|uniprotkb:Protein lysine acetyltransferase ELP3(gene name synonym)|uniprotkb:"tRNA uridine(34) acetyltransferase"(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476424|imex:IM-26985-385 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000146776(gene)|ensembl:ENST00000419735(transcript)|interpro:IPR013243(SCA7)|mint:Q9ULK2|refseq:NP_065776.1|refseq:NP_612504.1|refseq:NP_689962.1|ensembl:ENST00000318724|ensembl:ENSP00000326344|ensembl:ENSP00000410759|ensembl:ENST00000477775|ensembl:ENSP00000418476|refseq:XP_011514242.1|refseq:XP_011514256.1 refseq:NP_060561.3|refseq:NP_001271151.1|ensembl:ENSG00000134014(gene)|ensembl:ENST00000256398(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0001764"(neuron migration)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0002926"(tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007417"(central nervous system development)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0106261"("tRNA uridine(34) acetyltransferase activity")|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR006638(Elongator protein 3/MiaB/NifB)|interpro:IPR007197(Radical SAM)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR032432|interpro:IPR034687|interpro:IPR039661|mint:Q9H9T3|reactome:R-HSA-3214847|go:"GO:0008607"(phosphorylase kinase regulator activity)|refseq:NP_001271153.1|refseq:NP_001271154.1|refseq:NP_001271155.1|refseq:XP_006716417.1|dip:DIP-53227N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:oAY7Q/8MMAwsC4Ro7ocKmrBBIpA9606 rogid:KYzyxQWXiCNMIbrJSLUr/mqtCvo9606 rigid:YvhwMmfVv5EzR+s9je2yAGEhKQ4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9ULK2 uniprotkb:Q16540 intact:EBI-310660|ensembl:ENSP00000410759|uniprotkb:Q8N2T0|uniprotkb:A4D0Q2|uniprotkb:B4DTS1 intact:EBI-1046141|uniprotkb:A8MT29|uniprotkb:Q96Q71|ensembl:ENSP00000370930|ensembl:ENSP00000380466|ensembl:ENSP00000500123|ensembl:ENSP00000500896 psi-mi:at7l1_human(display_long)|uniprotkb:ATXN7L1(gene name)|psi-mi:ATXN7L1(display_short)|uniprotkb:KIAA1218(gene name synonym)|uniprotkb:ATXN7L4(gene name synonym)|uniprotkb:Ataxin-7-like protein 4(gene name synonym) psi-mi:rm23_human(display_long)|uniprotkb:L23 mitochondrial-related protein(gene name synonym)|uniprotkb:Ribosomal protein L23-like(gene name synonym)|uniprotkb:L23MRP(gene name synonym)|uniprotkb:RPL23L(gene name synonym)|uniprotkb:MRPL23(gene name)|psi-mi:MRPL23(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein uL23m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476424|imex:IM-26985-385 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000146776(gene)|ensembl:ENST00000419735(transcript)|interpro:IPR013243(SCA7)|mint:Q9ULK2|refseq:NP_065776.1|refseq:NP_612504.1|refseq:NP_689962.1|ensembl:ENST00000318724|ensembl:ENSP00000326344|ensembl:ENSP00000410759|ensembl:ENST00000477775|ensembl:ENSP00000418476|refseq:XP_011514242.1|refseq:XP_011514256.1 refseq:NP_066957.3|ensembl:ENSG00000214026(gene)|ensembl:ENSG00000288141(gene)|ensembl:ENST00000381519(transcript)|ensembl:ENST00000397298(transcript)|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|ensembl:ENST00000672185(transcript)|ensembl:ENST00000672523(transcript)|go:"GO:0001650"(fibrillar center)|rcsb pdb:7ODS|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR013025(Ribosomal protein L25/L23)|mint:Q16540|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:7ODT|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:7OF0 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:oAY7Q/8MMAwsC4Ro7ocKmrBBIpA9606 rogid:1TSlowXDlWVOW2PS1vv8Lu/e1vU9606 rigid:YvhwMmfVv5EzR+s9je2yAGEhKQ4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9ULK2 uniprotkb:Q92624 intact:EBI-310660|ensembl:ENSP00000410759|uniprotkb:Q8N2T0|uniprotkb:A4D0Q2|uniprotkb:B4DTS1 intact:EBI-743771|uniprotkb:O95095|uniprotkb:Q8WVC9|uniprotkb:A8K862|ensembl:ENSP00000083182 psi-mi:at7l1_human(display_long)|uniprotkb:ATXN7L1(gene name)|psi-mi:ATXN7L1(display_short)|uniprotkb:KIAA1218(gene name synonym)|uniprotkb:ATXN7L4(gene name synonym)|uniprotkb:Ataxin-7-like protein 4(gene name synonym) psi-mi:apbp2_human(display_long)|uniprotkb:Amyloid beta precursor protein-binding protein 2(gene name synonym)|uniprotkb:Protein interacting with APP tail 1(gene name synonym)|uniprotkb:APPBP2(gene name)|psi-mi:APPBP2(display_short)|uniprotkb:KIAA0228(gene name synonym)|uniprotkb:PAT1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476424|imex:IM-26985-385 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000146776(gene)|ensembl:ENST00000419735(transcript)|interpro:IPR013243(SCA7)|mint:Q9ULK2|refseq:NP_065776.1|refseq:NP_612504.1|refseq:NP_689962.1|ensembl:ENST00000318724|ensembl:ENSP00000326344|ensembl:ENSP00000410759|ensembl:ENST00000477775|ensembl:ENSP00000418476|refseq:XP_011514242.1|refseq:XP_011514256.1 refseq:NP_001269405.1|refseq:NP_006371.2|ensembl:ENSG00000062725(gene)|ensembl:ENST00000083182(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046907"(intracellular transport)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q92624|interpro:IPR042476 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:oAY7Q/8MMAwsC4Ro7ocKmrBBIpA9606 rogid:v3OsJTC6qSupyl7flB7A/tYhIDU9606 rigid:YvhwMmfVv5EzR+s9je2yAGEhKQ4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9ULK2 uniprotkb:P62820 intact:EBI-310660|ensembl:ENSP00000410759|uniprotkb:Q8N2T0|uniprotkb:A4D0Q2|uniprotkb:B4DTS1 intact:EBI-716845|uniprotkb:Q96N61|uniprotkb:Q9Y3T2|uniprotkb:P11476|uniprotkb:Q6FIE7|ensembl:ENSP00000387286|ensembl:ENSP00000497078 psi-mi:at7l1_human(display_long)|uniprotkb:ATXN7L1(gene name)|psi-mi:ATXN7L1(display_short)|uniprotkb:KIAA1218(gene name synonym)|uniprotkb:ATXN7L4(gene name synonym)|uniprotkb:Ataxin-7-like protein 4(gene name synonym) psi-mi:rab1a_human(display_long)|uniprotkb:YPT1-related protein(gene name synonym)|uniprotkb:RAB1A(gene name)|psi-mi:RAB1A(display_short)|uniprotkb:RAB1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476424|imex:IM-26985-385 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000146776(gene)|ensembl:ENST00000419735(transcript)|interpro:IPR013243(SCA7)|mint:Q9ULK2|refseq:NP_065776.1|refseq:NP_612504.1|refseq:NP_689962.1|ensembl:ENST00000318724|ensembl:ENSP00000326344|ensembl:ENSP00000410759|ensembl:ENST00000477775|ensembl:ENSP00000418476|refseq:XP_011514242.1|refseq:XP_011514256.1 refseq:NP_004152.1|refseq:NP_056358.1|ensembl:ENSG00000138069(gene)|ensembl:ENST00000409784(transcript)|ensembl:ENST00000649427(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007030"(Golgi organization)|go:"GO:0012505"(endomembrane system)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016477"(cell migration)|go:"GO:0019068"(virion assembly)|go:"GO:0030252"(growth hormone secretion)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0032402"(melanosome transport)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042470"(melanosome)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045296"(cadherin binding)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:1903020"(positive regulation of glycoprotein metabolic process)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62820|rcsb pdb:2FOL|rcsb pdb:2WWX|rcsb pdb:3L0I|rcsb pdb:3SFV|rcsb pdb:3TKL|rcsb pdb:4FMB|rcsb pdb:4FMC|rcsb pdb:4FMD|rcsb pdb:4FME|rcsb pdb:4IRU|rcsb pdb:4JVS|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-8873719|reactome:R-HSA-8876198|dip:DIP-1063N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:oAY7Q/8MMAwsC4Ro7ocKmrBBIpA9606 rogid:Pa9NYKiCNXtxRwthh1r/pGbZyf09606 rigid:YvhwMmfVv5EzR+s9je2yAGEhKQ4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9ULK2 uniprotkb:Q5JUX0 intact:EBI-310660|ensembl:ENSP00000410759|uniprotkb:Q8N2T0|uniprotkb:A4D0Q2|uniprotkb:B4DTS1 intact:EBI-1642527|uniprotkb:Q8N5D9|uniprotkb:B7Z8W2|uniprotkb:B2RUW3|ensembl:ENSP00000364054|ensembl:ENSP00000491179|ensembl:ENSP00000491624|ensembl:ENSP00000491751|ensembl:ENSP00000492344|ensembl:ENSP00000492381|ensembl:ENSP00000492795 psi-mi:at7l1_human(display_long)|uniprotkb:ATXN7L1(gene name)|psi-mi:ATXN7L1(display_short)|uniprotkb:KIAA1218(gene name synonym)|uniprotkb:ATXN7L4(gene name synonym)|uniprotkb:Ataxin-7-like protein 4(gene name synonym) psi-mi:spin3_human(display_long)|uniprotkb:SPIN3(gene name)|psi-mi:SPIN3(display_short)|uniprotkb:Spindlin-like protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476424|imex:IM-26985-385 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000146776(gene)|ensembl:ENST00000419735(transcript)|interpro:IPR013243(SCA7)|mint:Q9ULK2|refseq:NP_065776.1|refseq:NP_612504.1|refseq:NP_689962.1|ensembl:ENST00000318724|ensembl:ENSP00000326344|ensembl:ENSP00000410759|ensembl:ENST00000477775|ensembl:ENSP00000418476|refseq:XP_011514242.1|refseq:XP_011514256.1 refseq:NP_001010862.2|refseq:XP_006724640.1|refseq:XP_006724641.1|refseq:XP_016884804.1|ensembl:ENSG00000204271(gene)|ensembl:ENST00000374919(transcript)|ensembl:ENST00000638257(transcript)|ensembl:ENST00000638289(transcript)|ensembl:ENST00000638386(transcript)|ensembl:ENST00000638712(transcript)|ensembl:ENST00000639007(transcript)|ensembl:ENST00000639605(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007276"(gamete generation)|go:"GO:0035064"(methylated histone binding)|interpro:IPR003671(Spindlin/spermiogenesis-specific protein)|interpro:IPR029567|interpro:IPR042567|mint:Q5JUX0|rcsb pdb:5A1H - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:oAY7Q/8MMAwsC4Ro7ocKmrBBIpA9606 rogid:Z4PHGiFUPGeFRxSjg6rzBFnXv7g9606 rigid:YvhwMmfVv5EzR+s9je2yAGEhKQ4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9ULK2 uniprotkb:O95163 intact:EBI-310660|ensembl:ENSP00000410759|uniprotkb:Q8N2T0|uniprotkb:A4D0Q2|uniprotkb:B4DTS1 intact:EBI-347559|uniprotkb:Q9H327|uniprotkb:Q9UG87|uniprotkb:Q5JSV2|ensembl:ENSP00000363779|ensembl:ENSP00000501893 psi-mi:at7l1_human(display_long)|uniprotkb:ATXN7L1(gene name)|psi-mi:ATXN7L1(display_short)|uniprotkb:KIAA1218(gene name synonym)|uniprotkb:ATXN7L4(gene name synonym)|uniprotkb:Ataxin-7-like protein 4(gene name synonym) psi-mi:elp1_human(display_long)|uniprotkb:ELP1(gene name)|psi-mi:ELP1(display_short)|uniprotkb:IKAP(gene name synonym)|uniprotkb:IKBKAP(gene name synonym)|uniprotkb:p150(gene name synonym)|uniprotkb:IkappaB kinase complex-associated protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476424|imex:IM-26985-385 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000146776(gene)|ensembl:ENST00000419735(transcript)|interpro:IPR013243(SCA7)|mint:Q9ULK2|refseq:NP_065776.1|refseq:NP_612504.1|refseq:NP_689962.1|ensembl:ENST00000318724|ensembl:ENSP00000326344|ensembl:ENSP00000410759|ensembl:ENST00000477775|ensembl:ENSP00000418476|refseq:XP_011514242.1|refseq:XP_011514256.1 dip:DIP-27579N|refseq:NP_003631.2|refseq:NP_001305289.1|ensembl:ENSG00000070061(gene)|ensembl:ENST00000374647(transcript)|ensembl:ENST00000675406(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002926"(tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0033588"(elongator holoenzyme complex)|interpro:IPR006849(IKI3)|interpro:IPR015943(WD40/YVTN repeat-like)|mint:O95163|rcsb pdb:5CQR|reactome:R-HSA-3214847|go:"GO:0005829"(cytosol) - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:oAY7Q/8MMAwsC4Ro7ocKmrBBIpA9606 rogid:hl+inV6TcN+DGu9CwE3SitkHiI09606 rigid:YvhwMmfVv5EzR+s9je2yAGEhKQ4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9ULK2 uniprotkb:P08134 intact:EBI-310660|ensembl:ENSP00000410759|uniprotkb:Q8N2T0|uniprotkb:A4D0Q2|uniprotkb:B4DTS1 intact:EBI-747589|uniprotkb:Q6ICN3|uniprotkb:B3KSW1|ensembl:ENSP00000285735|ensembl:ENSP00000345236|ensembl:ENSP00000358646|ensembl:ENSP00000358647|ensembl:ENSP00000358651|ensembl:ENSP00000358652|ensembl:ENSP00000358656 psi-mi:at7l1_human(display_long)|uniprotkb:ATXN7L1(gene name)|psi-mi:ATXN7L1(display_short)|uniprotkb:KIAA1218(gene name synonym)|uniprotkb:ATXN7L4(gene name synonym)|uniprotkb:Ataxin-7-like protein 4(gene name synonym) psi-mi:rhoc_human(display_long)|uniprotkb:Rho cDNA clone 9(gene name synonym)|uniprotkb:RHOC(gene name)|psi-mi:RHOC(display_short)|uniprotkb:ARH9(gene name synonym)|uniprotkb:ARHC(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476424|imex:IM-26985-385 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000146776(gene)|ensembl:ENST00000419735(transcript)|interpro:IPR013243(SCA7)|mint:Q9ULK2|refseq:NP_065776.1|refseq:NP_612504.1|refseq:NP_689962.1|ensembl:ENST00000318724|ensembl:ENSP00000326344|ensembl:ENSP00000410759|ensembl:ENST00000477775|ensembl:ENSP00000418476|refseq:XP_011514242.1|refseq:XP_011514256.1 refseq:NP_001036143.1|refseq:NP_001036144.1|refseq:NP_786886.1|ensembl:ENSG00000155366(gene)|ensembl:ENST00000285735(transcript)|ensembl:ENST00000339083(transcript)|ensembl:ENST00000369632(transcript)|ensembl:ENST00000369633(transcript)|ensembl:ENST00000369637(transcript)|ensembl:ENST00000369638(transcript)|ensembl:ENST00000369642(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032420"(stereocilium)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043297"(apical junction assembly)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0060193"(positive regulation of lipase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902766"(skeletal muscle satellite cell migration)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P08134|rcsb pdb:1Z2C|rcsb pdb:2GCN|rcsb pdb:2GCO|rcsb pdb:2GCP|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5663220|reactome:R-HSA-5666185|reactome:R-HSA-9013106 - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:oAY7Q/8MMAwsC4Ro7ocKmrBBIpA9606 rogid:CPt/q5soDZILGfkngD41Y1U4eys9606 rigid:YvhwMmfVv5EzR+s9je2yAGEhKQ4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15265 uniprotkb:Q8N488 intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym) psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476358|imex:IM-26985-529 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2 refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity) - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rigid:C4zZd4RMQmM5u3F5a6iSlRP0GEo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15265 uniprotkb:Q16514 intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216 intact:EBI-1034238|uniprotkb:Q15775|uniprotkb:Q5T077|uniprotkb:D3DPM5|ensembl:ENSP00000263974|ensembl:ENSP00000362930 psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym) psi-mi:taf12_human(display_long)|uniprotkb:TAF12(gene name)|psi-mi:TAF12(display_short)|uniprotkb:TAF15(gene name synonym)|uniprotkb:TAF2J(gene name synonym)|uniprotkb:TAFII20(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 20/15 kDa subunits(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476358|imex:IM-26985-529 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2 refseq:NP_001128690.1|refseq:NP_005635.1|ensembl:ENSG00000120656(gene)|ensembl:ENST00000263974(transcript)|ensembl:ENST00000373824(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000125"|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR003228(Transcription initiation factor TFIID)|interpro:IPR009072(Histone-fold)|interpro:IPR037794|mint:Q16514|rcsb pdb:1H3O|rcsb pdb:6MZC|rcsb pdb:6MZD|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGF|rcsb pdb:7EGG|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-3214847|dip:DIP-496N - - comment:"author score: 35" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606 rogid:nzWJez/7zwBDPSEGXSPgCO46nng9606 rigid:C4zZd4RMQmM5u3F5a6iSlRP0GEo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15265 uniprotkb:Q9NPA8 intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216 intact:EBI-719226|uniprotkb:B2RE52|intact:EBI-10972054|uniprotkb:G3V117|ensembl:ENSP00000429986 psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym) psi-mi:eny2_human(display_long)|uniprotkb:Enhancer of yellow 2 transcription factor homolog(gene name synonym)|uniprotkb:DC6(orf name)|uniprotkb:ENY2(gene name)|psi-mi:ENY2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476358|imex:IM-26985-529 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2 refseq:NP_001180486.1|refseq:NP_064574.1|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0061179"(negative regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071819"(DUBm complex)|interpro:IPR018783|interpro:IPR038212|mint:Q9NPA8|rcsb pdb:4DHX|go:"GO:0030374"(nuclear receptor coactivator activity)|reactome:R-HSA-3214847|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0015031"(protein transport)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|ensembl:ENSG00000120533(gene)|ensembl:ENST00000521688(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II) - - comment:"author score: 36" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606 rogid:CJmjqxLqgpxrqtvVVFcgxW5nloE9606 rigid:C4zZd4RMQmM5u3F5a6iSlRP0GEo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15265 uniprotkb:Q92830 intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216 intact:EBI-477622|uniprotkb:Q9UCW1|uniprotkb:Q8N1A2|ensembl:ENSP00000225916 psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym) psi-mi:kat2a_human(display_long)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:STAF97(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:GCN5L2(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:KAT2A(gene name)|psi-mi:KAT2A(display_short)|uniprotkb:GCN5(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476358|imex:IM-26985-529 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2 refseq:NP_066564.2|ensembl:ENSG00000108773(gene)|ensembl:ENST00000225916(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q92830|rcsb pdb:1F68|rcsb pdb:1Z4R|rcsb pdb:3D7C|rcsb pdb:5H84|rcsb pdb:5H86|rcsb pdb:5MLJ|rcsb pdb:5TRL|rcsb pdb:5TRM|rcsb pdb:6J3P|reactome:R-HSA-1912408|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214847|reactome:R-HSA-350054|reactome:R-HSA-5250924|reactome:R-HSA-5689880|reactome:R-HSA-73762|reactome:R-HSA-8941856|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|reactome:R-HSA-9013508|reactome:R-HSA-9013695|refseq:XP_016879937.1|dip:DIP-28146N - - comment:"author score: 42" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606 rogid:PwDTlmU+caK91Xbiv7xm4xejZok9606 rigid:C4zZd4RMQmM5u3F5a6iSlRP0GEo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15265 uniprotkb:Q16594 intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216 intact:EBI-712521|ensembl:ENSP00000370193|ensembl:ENSP00000421873|ensembl:ENSP00000477611|ensembl:ENSP00000477750|ensembl:ENSP00000478935|ensembl:ENSP00000217893|uniprotkb:Q5U0D1|uniprotkb:Q9BTS1|uniprotkb:D3DWA3|intact:EBI-8645823|intact:MINT-8163548 psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym) psi-mi:taf9_human(display_long)|uniprotkb:Transcription initiation factor TFIID 31 kDa subunit(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 32 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II TBP-associated factor subunit G(gene name synonym)|uniprotkb:STAF31/32(gene name synonym)|uniprotkb:TAF9(gene name)|psi-mi:TAF9(display_short)|uniprotkb:TAF2G(gene name synonym)|uniprotkb:TAFII31(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476358|imex:IM-26985-529 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2 ensembl:ENST00000217893(transcript)|ensembl:ENST00000328663(transcript)|ensembl:ENST00000506736(transcript)|ensembl:ENST00000615404(transcript)|ensembl:ENST00000616867(transcript)|ensembl:ENST00000617893(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000125"|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0030914"|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0070761"(pre-snoRNP complex)|go:"GO:0071339"(MLL1 complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|interpro:IPR003162(Transcription factor TAFII-31)|interpro:IPR009072(Histone-fold)|mint:Q16594|rcsb pdb:6F3T|rcsb pdb:6MZC|rcsb pdb:6MZD|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGF|rcsb pdb:7EGG|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-3214847|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-6807505|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|ensembl:ENSG00000273841(gene)|ensembl:ENSG00000276463(gene)|refseq:NP_001015892.1|refseq:NP_003178.1|dip:DIP-435N - - comment:"author score: 48" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606 rogid:Drikn9IwpWQXbTTXGqwf1hlRNE09606 rigid:C4zZd4RMQmM5u3F5a6iSlRP0GEo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15265 uniprotkb:Q12962 intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216 intact:EBI-708376|uniprotkb:O00703|uniprotkb:Q13175|uniprotkb:Q6FH13|ensembl:ENSP00000299424 psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym) psi-mi:taf10_human(display_long)|uniprotkb:Transcription initiation factor TFIID 30 kDa subunit(gene name synonym)|uniprotkb:STAF28(gene name synonym)|uniprotkb:TAF10(gene name)|psi-mi:TAF10(display_short)|uniprotkb:TAF2H(gene name synonym)|uniprotkb:TAFII30(gene name synonym)|uniprotkb:TAF2A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476358|imex:IM-26985-529 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2 refseq:NP_006275.1|dip:DIP-297N|ensembl:ENSG00000166337(gene)|ensembl:ENST00000299424(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000125"|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006915"(apoptotic process)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0034622"|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR003923(Transcription initiation factor TFIID, 23-30 kDa subunit)|mint:Q12962|rcsb pdb:2F69|rcsb pdb:3M53|rcsb pdb:3M54|rcsb pdb:3M55|rcsb pdb:3M56|rcsb pdb:3M57|rcsb pdb:3M58|rcsb pdb:3M59|rcsb pdb:3M5A|rcsb pdb:4J7F|rcsb pdb:4J7I|rcsb pdb:4J83|rcsb pdb:4J8O|rcsb pdb:4WV4|rcsb pdb:5EG2|rcsb pdb:6MZC|rcsb pdb:6MZD|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGF|rcsb pdb:7EGG|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-3214847|reactome:R-HSA-5689880|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042 - - comment:"author score: 51" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606 rogid:8HFLtF8faq1WlDk5+r4B/+4Ldeg9606 rigid:C4zZd4RMQmM5u3F5a6iSlRP0GEo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15265 uniprotkb:Q9UPT9 intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216 intact:EBI-723510|ensembl:ENSP00000261497|uniprotkb:A0JNS3|uniprotkb:Q2NLE2|uniprotkb:Q6MZY4|uniprotkb:Q8TBS8|uniprotkb:Q96IW5 psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym) psi-mi:ubp22_human(display_long)|uniprotkb:Ubiquitin-specific-processing protease 22(gene name synonym)|uniprotkb:Deubiquitinating enzyme 22(gene name synonym)|uniprotkb:USP22(gene name)|psi-mi:USP22(display_short)|uniprotkb:KIAA1063(gene name synonym)|uniprotkb:USP3L(gene name synonym)|uniprotkb:Ubiquitin thioesterase 22(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476358|imex:IM-26985-529 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2 refseq:NP_056091.1|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018200|go:"GO:0007049"(cell cycle)|interpro:IPR028889|interpro:IPR038765|mint:Q9UPT9|go:"GO:0008270"(zinc ion binding)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|reactome:R-HSA-3214847|go:"GO:0016574"(histone ubiquitination)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019899"(enzyme binding)|reactome:R-HSA-5689880|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001607(Zinc finger, UBP-type)|ensembl:ENSG00000124422(gene)|ensembl:ENST00000261497(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process) - - comment:"author score: 58" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606 rogid:8n1lOTC7I8dP3RY1IEUtIkJiSXc9606 rigid:C4zZd4RMQmM5u3F5a6iSlRP0GEo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15265 uniprotkb:Q92831 intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216 intact:EBI-477430|uniprotkb:Q6NSK1|ensembl:ENSP00000263754 psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym) psi-mi:kat2b_human(display_long)|uniprotkb:P300/CBP-associated factor(gene name synonym)|uniprotkb:PCAF(gene name synonym)|uniprotkb:Lysine acetyltransferase 2B(gene name synonym)|uniprotkb:Histone acetyltransferase PCAF(gene name synonym)|uniprotkb:KAT2B(gene name)|psi-mi:KAT2B(display_short)|uniprotkb:Spermidine acetyltransferase KAT2B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476358|imex:IM-26985-529 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2 ensembl:ENSG00000114166(gene)|ensembl:ENST00000263754(transcript)|go:"GO:0000125"|go:"GO:0000776"(kinetochore)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004145"(diamine N-acetyltransferase activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006473"(protein acetylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031672"(A band)|go:"GO:0031674"(I band)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|refseq:NP_003875.3|go:"GO:0043970"(histone H3-K9 acetylation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060173"(limb development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:2000233"(negative regulation of rRNA processing)|interpro:IPR000182(GCN5-related N-acetyltransferase)|go:"GO:0043966"(histone H3 acetylation)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|go:"GO:0042826"(histone deacetylase binding)|interpro:IPR036427|interpro:IPR037800|mint:Q92831|rcsb pdb:1CM0|rcsb pdb:1JM4|rcsb pdb:1N72|rcsb pdb:1WUG|rcsb pdb:1WUM|rcsb pdb:1ZS5|rcsb pdb:2RNW|rcsb pdb:2RNX|rcsb pdb:3GG3|rcsb pdb:4NSQ|rcsb pdb:5FDZ|rcsb pdb:5FE0|rcsb pdb:5FE1|rcsb pdb:5FE2|rcsb pdb:5FE3|rcsb pdb:5FE4|rcsb pdb:5FE5|rcsb pdb:5FE6|rcsb pdb:5FE7|rcsb pdb:5FE8|rcsb pdb:5FE9|rcsb pdb:5LVQ|rcsb pdb:5LVR|rcsb pdb:5MKX|rcsb pdb:6J3O|reactome:R-HSA-1912408|reactome:R-HSA-2032785|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214847|reactome:R-HSA-350054|reactome:R-HSA-5250924|reactome:R-HSA-5578768|reactome:R-HSA-5689901|reactome:R-HSA-73762|reactome:R-HSA-8936459|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9018519|reactome:R-HSA-9617629|dip:DIP-29778N - - comment:"author score: 62" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606 rogid:g0Gzr/F28rlhpv1qBl+kMEuwlZI9606 rigid:C4zZd4RMQmM5u3F5a6iSlRP0GEo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15265 uniprotkb:O75486 intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216 intact:EBI-896640|uniprotkb:A6NKG9|uniprotkb:O76066|uniprotkb:Q5TAV9|uniprotkb:B2R9Q5|uniprotkb:Q86VN7|intact:EBI-11061133|ensembl:ENSP00000360514|ensembl:ENSP00000436411 psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym) psi-mi:supt3_human(display_long)|uniprotkb:SUPT3H(gene name)|psi-mi:SUPT3H(display_short)|uniprotkb:SPT3(gene name synonym)|uniprotkb:SPT3-like protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476358|imex:IM-26985-529 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2 refseq:XP_016866861.1|refseq:NP_003590.1|refseq:NP_852001.1|refseq:XP_016866860.1|dip:DIP-28148N|ensembl:ENSG00000196284(gene)|ensembl:ENST00000371459(transcript)|ensembl:ENST00000475057(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003195(Transcription initiation factor IID, 18 kDa subunit)|interpro:IPR009072(Histone-fold)|mint:O75486|reactome:R-HSA-3214847 - - comment:"author score: 65" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606 rogid:P+62Ufs6GyoQYKCpbNaab5KzYOc9606 rigid:C4zZd4RMQmM5u3F5a6iSlRP0GEo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15265 uniprotkb:Q9Y4A5 intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216 intact:EBI-399128|uniprotkb:O75218|uniprotkb:Q9Y631|uniprotkb:Q9Y6H4|uniprotkb:A4D265|ensembl:ENSP00000352925 psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym) psi-mi:trrap_human(display_long)|uniprotkb:TRRAP(gene name)|psi-mi:TRRAP(display_short)|uniprotkb:PAF400(gene name synonym)|uniprotkb:350/400 kDa PCAF-associated factor(gene name synonym)|uniprotkb:STAF40(gene name synonym)|uniprotkb:Tra1 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476358|imex:IM-26985-529 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2 refseq:NP_003487.1|ensembl:ENSG00000196367(gene)|ensembl:ENST00000359863(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000125"|go:"GO:0000812"(Swr1 complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006281"(DNA repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016310"(phosphorylation)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033317|mint:Q9Y4A5|reactome:R-HSA-201722|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_001231509.1|dip:DIP-28149N - - comment:"author score: 73" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606 rogid:bGoQLXxMT0zZ0jVW+2s4hUwnBA49606 rigid:C4zZd4RMQmM5u3F5a6iSlRP0GEo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15265 uniprotkb:Q14CW9 intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216 intact:EBI-949215|ensembl:ENSP00000374035|ensembl:ENSP00000465614|uniprotkb:Q96N40|uniprotkb:Q9NPU5|uniprotkb:Q8IY68 psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym) psi-mi:at7l3_human(display_long)|uniprotkb:ATXN7L3(gene name)|psi-mi:ATXN7L3(display_short)|uniprotkb:SAGA-associated factor 11 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476358|imex:IM-26985-529 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2 ensembl:ENSG00000087152(gene)|ensembl:ENST00000389384(transcript)|ensembl:ENST00000587097(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071819"(DUBm complex)|interpro:IPR013243(SCA7)|interpro:IPR013246(Sgf11, transcriptional regulation)|mint:Q14CW9|rcsb pdb:2KKT|reactome:R-HSA-3214847|refseq:NP_001092303.1|refseq:NP_064603.1|refseq:XP_016880374.1|refseq:XP_016880375.1 - - comment:"author score: 77" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606 rogid:r0Yw6RIZ9DbDlu2xE5hOFPlvk849606 rigid:C4zZd4RMQmM5u3F5a6iSlRP0GEo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15265 uniprotkb:O75528 intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216 intact:EBI-473249|uniprotkb:Q9UFS2|intact:EBI-28973289|ensembl:ENSP00000307684|ensembl:ENSP00000393471|uniprotkb:Q6FI83 psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym) psi-mi:tada3_human(display_long)|uniprotkb:ADA3 homolog(gene name synonym)|uniprotkb:STAF54(gene name synonym)|uniprotkb:TADA3(gene name)|psi-mi:TADA3(display_short)|uniprotkb:ADA3(gene name synonym)|uniprotkb:TADA3L(gene name synonym)|uniprotkb:Transcriptional adapter 3-like(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476358|imex:IM-26985-529 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2 ensembl:ENSG00000171148(gene)|ensembl:ENST00000301964(transcript)|ensembl:ENST00000440161(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030914"|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR019340|mint:O75528|reactome:R-HSA-3214847|reactome:R-HSA-5689880|ensembl:ENSP00000307684|ensembl:ENST00000343450|ensembl:ENSP00000343649|ensembl:ENSP00000393471|refseq:NP_006345.1|refseq:NP_597814.1|refseq:NP_001265199.1 - - comment:"author score: 81" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606 rogid:5NQkQiw+G/8uL2fjoMgW8+mTB8o9606 rigid:C4zZd4RMQmM5u3F5a6iSlRP0GEo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15265 uniprotkb:Q8NEM7 intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216 intact:EBI-946984|uniprotkb:Q71RF3|uniprotkb:Q9Y6A6|ensembl:ENSP00000218894|uniprotkb:E7ER46 psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym) psi-mi:sp20h_human(display_long)|uniprotkb:SUPT20H(gene name)|psi-mi:SUPT20H(display_short)|uniprotkb:C13orf19(gene name synonym)|uniprotkb:FAM48A(gene name synonym)|uniprotkb:p38-interacting protein(gene name synonym)|uniprotkb:FP757(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476358|imex:IM-26985-529 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2 refseq:NP_001265409.1|refseq:NP_001265410.1|refseq:NP_001265411.1|refseq:NP_001014308.2|refseq:NP_060039.1|ensembl:ENSG00000102710(gene)|ensembl:ENST00000350612(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006914"(autophagy)|go:"GO:0007369"(gastrulation)|go:"GO:0070461"(SAGA-type complex)|interpro:IPR021950|mint:Q8NEM7|reactome:R-HSA-3214847 - - comment:"author score: 82" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606 rogid:7s9ChKIewCopRWC7otwhnH6hYEs9606 rigid:C4zZd4RMQmM5u3F5a6iSlRP0GEo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15265 uniprotkb:O94864 intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216 intact:EBI-722912|uniprotkb:Q6IB21|uniprotkb:Q9H2T6|uniprotkb:B4E3W3|ensembl:ENSP00000336750 psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym) psi-mi:st65g_human(display_long)|uniprotkb:SPTF-associated factor 65 gamma(gene name synonym)|uniprotkb:Suppressor of Ty 7-like(gene name synonym)|uniprotkb:Adenocarcinoma antigen ART1(gene name synonym)|uniprotkb:SUPT7L(gene name)|psi-mi:SUPT7L(display_short)|uniprotkb:KIAA0764(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476358|imex:IM-26985-529 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2 refseq:NP_001269658.1|refseq:NP_001269659.1|refseq:NP_001269660.1|refseq:NP_001269661.1|refseq:NP_055675.1|refseq:XP_005264729.1|ensembl:ENSG00000119760(gene)|ensembl:ENST00000337768(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0030914"|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|interpro:IPR006565(Bromodomain transcription factor)|interpro:IPR009072(Histone-fold)|interpro:IPR039460|mint:O94864|reactome:R-HSA-3214847 - - comment:"author score: 85" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606 rogid:v26YjDoNB/9ekC4xRZEm77Roruw9606 rigid:C4zZd4RMQmM5u3F5a6iSlRP0GEo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15265 uniprotkb:Q86TJ2 intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216 intact:EBI-2512219|uniprotkb:Q6MZG9|uniprotkb:B3KSN0|uniprotkb:B3KU86|uniprotkb:A4QMR7|uniprotkb:A0AUJ8|ensembl:ENSP00000308022 psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym) psi-mi:tad2b_human(display_long)|uniprotkb:TADA2B(gene name)|psi-mi:TADA2B(display_short)|uniprotkb:ADA2B(gene name synonym)|uniprotkb:ADA2-like protein beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476358|imex:IM-26985-529 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2 refseq:XP_011511897.1|refseq:NP_689506.2|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|mint:Q86TJ2|reactome:R-HSA-3214847|reactome:R-HSA-5689880|interpro:IPR009057(Homeodomain-like)|ensembl:ENSG00000173011(gene)|ensembl:ENST00000310074(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030914"|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0070461"(SAGA-type complex)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding) - - comment:"author score: 94" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606 rogid:ShA8/bknqf6XcaEWL3YFWOz9s9c9606 rigid:C4zZd4RMQmM5u3F5a6iSlRP0GEo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15265 uniprotkb:Q96BN2 intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216 intact:EBI-2512236|ensembl:ENSP00000356848|uniprotkb:A8K4J9 psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym) psi-mi:tada1_human(display_long)|uniprotkb:TADA1(gene name)|psi-mi:TADA1(display_short)|uniprotkb:TADA1L(gene name synonym)|uniprotkb:Transcriptional adapter 1-like protein(gene name synonym)|uniprotkb:SPT3-associated factor 42(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476358|imex:IM-26985-529 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2 ensembl:ENSG00000152382(gene)|ensembl:ENST00000367874(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030914"|go:"GO:0043966"(histone H3 acetylation)|interpro:IPR024738|mint:Q96BN2|reactome:R-HSA-3214847|refseq:NP_444281.1 - - comment:"author score: 94" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606 rogid:07aGEsEjtD884LVJ6Jlj12+TdK49606 rigid:C4zZd4RMQmM5u3F5a6iSlRP0GEo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15265 uniprotkb:Q9HBM6 intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216 intact:EBI-751601|uniprotkb:Q9Y2S3|uniprotkb:B2RUZ9|ensembl:ENSP00000339917 psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym) psi-mi:taf9b_human(display_long)|uniprotkb:Transcription initiation factor TFIID subunit 9-like(gene name synonym)|uniprotkb:Transcription-associated factor TAFII31L(gene name synonym)|uniprotkb:Neuronal cell death-related protein 7(gene name synonym)|uniprotkb:TAF9B(gene name)|psi-mi:TAF9B(display_short)|uniprotkb:TAF9L(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476358|imex:IM-26985-529 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2 refseq:NP_057059.2|ensembl:ENSG00000187325(gene)|ensembl:ENST00000341864(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|interpro:IPR003162(Transcription factor TAFII-31)|interpro:IPR009072(Histone-fold)|mint:Q9HBM6|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-5689880|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042 - - comment:"author score: 98" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606 rogid:8+i5lmcx4OcgCEbk2F9MS8bYhos9606 rigid:C4zZd4RMQmM5u3F5a6iSlRP0GEo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15265 uniprotkb:O75529 intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216 intact:EBI-1785876|uniprotkb:Q8IW31|uniprotkb:Q5TDI6|uniprotkb:Q5TDI5|ensembl:ENSP00000258281 psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym) psi-mi:taf5l_human(display_long)|uniprotkb:TAF5L(gene name)|psi-mi:TAF5L(display_short)|uniprotkb:PAF65B(gene name synonym)|uniprotkb:PCAF-associated factor 65 beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476358|imex:IM-26985-529 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2 refseq:NP_001020418.1|refseq:NP_055224.1|refseq:XP_005273156.1|dip:DIP-28147N|ensembl:ENSG00000135801(gene)|ensembl:ENST00000258281(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016607"(nuclear speck)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:1904672"(regulation of somatic stem cell population maintenance)|interpro:IPR001680(WD40 repeat)|interpro:IPR007582(WD40 associated region in TFIID subunit)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037264|interpro:IPR037783|interpro:IPR037826|mint:O75529|reactome:R-HSA-3214847 - - comment:"author score: 99" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606 rogid:3D2y64CWMvwok3BvV2CpH6iX84E9606 rigid:C4zZd4RMQmM5u3F5a6iSlRP0GEo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15265 uniprotkb:Q96ES7 intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216 intact:EBI-743117|ensembl:ENSP00000316114|uniprotkb:Q96MF5 psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym) psi-mi:sgf29_human(display_long)|uniprotkb:SGF29(gene name)|psi-mi:SGF29(display_short)|uniprotkb:CCDC101(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 101(gene name synonym)|uniprotkb:SAGA complex-associated factor 29(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476358|imex:IM-26985-529 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2 ensembl:ENSG00000176476(gene)|ensembl:ENST00000317058(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0016573"(histone acetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0071169"(establishment of protein localization to chromatin)|interpro:IPR010750(Protein of unknown function DUF1325)|interpro:IPR037802|mint:Q96ES7|rcsb pdb:3LX7|rcsb pdb:3ME9|refseq:NP_612423.1|rcsb pdb:3MEA|rcsb pdb:3MET|rcsb pdb:3MEU|rcsb pdb:3MEV|rcsb pdb:3MEW|rcsb pdb:5C0M|reactome:R-HSA-3214847 - - comment:"author score: 104" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606 rogid:4uvy31cdeHtlQ4BHWSOLE8Szkq49606 rigid:C4zZd4RMQmM5u3F5a6iSlRP0GEo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15265 uniprotkb:Q9Y6J9 intact:EBI-708350|ensembl:ENSP00000295900|ensembl:ENSP00000420234|ensembl:ENSP00000501377|uniprotkb:O75328|uniprotkb:O75329|uniprotkb:Q9Y6P8|uniprotkb:B4E207|uniprotkb:E9PHP9|intact:EBI-3866216 intact:EBI-743984|uniprotkb:Q96HA6|uniprotkb:B2RAT0|ensembl:ENSP00000294168 psi-mi:atx7_human(display_long)|uniprotkb:Spinocerebellar ataxia type 7 protein(gene name synonym)|uniprotkb:ATXN7(gene name)|psi-mi:ATXN7(display_short)|uniprotkb:SCA7(gene name synonym) psi-mi:taf6l_human(display_long)|uniprotkb:PCAF-associated factor 65-alpha(gene name synonym)|uniprotkb:TAF6L(gene name)|psi-mi:TAF6L(display_short)|uniprotkb:PAF65A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476358|imex:IM-26985-529 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000163635(gene)|ensembl:ENST00000295900(transcript)|ensembl:ENST00000487717(transcript)|ensembl:ENST00000674280(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006997"(nucleus organization)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016578"(histone deubiquitination)|interpro:IPR013243(SCA7)|interpro:IPR030706|mint:O15265|rcsb pdb:2KKR|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_000324.1|refseq:NP_001170858.1|refseq:NP_001121621.2 refseq:NP_006464.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0030914"|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904672"(regulation of somatic stem cell population maintenance)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|interpro:IPR009072(Histone-fold)|interpro:IPR011442(Protein of unknown function DUF1546)|interpro:IPR037796|mint:Q9Y6J9|reactome:R-HSA-3214847|ensembl:ENSG00000162227(gene)|ensembl:ENST00000294168(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000124"(SAGA complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated) - - comment:"author score: 109" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wN6wVOLicbW9WdEVvYmiDrfmevk9606 rogid:ZcrK24blWTsAkCgruDbSiUflbtA9606 rigid:C4zZd4RMQmM5u3F5a6iSlRP0GEo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60238 uniprotkb:Q96H55 intact:EBI-849893|uniprotkb:Q5JW63|uniprotkb:Q8NF87|uniprotkb:B0AZS9|intact:EBI-28977676|ensembl:ENSP00000370003 intact:EBI-10983249|uniprotkb:Q59GS4|uniprotkb:Q9H5X2|ensembl:ENSP00000479518|ensembl:ENSP00000480242 psi-mi:bni3l_human(display_long)|uniprotkb:NIP3-like protein X(gene name synonym)|uniprotkb:BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A(gene name synonym)|uniprotkb:Adenovirus E1B19K-binding protein B5(gene name synonym)|uniprotkb:BNIP3L(gene name)|psi-mi:BNIP3L(display_short)|uniprotkb:BNIP3A(gene name synonym)|uniprotkb:BNIP3H(gene name synonym)|uniprotkb:NIX(gene name synonym) psi-mi:myo19_human(display_long)|uniprotkb:MYO19(gene name)|psi-mi:MYO19(display_short)|uniprotkb:MYOHD1(gene name synonym)|uniprotkb:Myosin head domain-containing protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476634|imex:IM-26985-305 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004322.1|ensembl:ENSP00000370003|ensembl:ENST00000518611|ensembl:ENSP00000429851|ensembl:ENST00000520409|ensembl:ENSP00000428597|ensembl:ENST00000523515|ensembl:ENSP00000429698|dip:DIP-35187N|refseq:NP_001317420.1|ensembl:ENSG00000104765(gene)|ensembl:ENST00000380629(transcript)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016607"(nuclear speck)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0035694"(mitochondrial protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0051607"(defense response to virus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|interpro:IPR010548(BNIP3)|mint:O60238|reactome:R-HSA-6803204 refseq:NP_001028752.1|refseq:NP_001157207.1|refseq:NP_079385.2|ensembl:ENSG00000278259(gene)|ensembl:ENSG00000278372(gene)|ensembl:ENST00000614623(transcript)|ensembl:ENST00000618519(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016459"(myosin complex)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0031982"(vesicle)|go:"GO:0032027"(myosin light chain binding)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034642"(mitochondrion migration along actin filament)|go:"GO:0051015"(actin filament binding)|go:"GO:0060002"(plus-end directed microfilament motor activity)|go:"GO:0090140"(regulation of mitochondrial fission)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR027417|interpro:IPR036035|interpro:IPR036961|mint:Q96H55|reactome:R-HSA-9013419|reactome:R-HSA-9013425 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:GPDlK/z2VOVzJspIhN8XNFPSVMo9606 rogid:coJYx89cip3wKcsCF65cbMPBt7Y9606 rigid:B3QrLGZhSEw2pTkCzm4azljLUxg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60238 uniprotkb:Q9P0W8 intact:EBI-849893|uniprotkb:Q5JW63|uniprotkb:Q8NF87|uniprotkb:B0AZS9|intact:EBI-28977676|ensembl:ENSP00000370003 intact:EBI-6152737|uniprotkb:Q5BKY5|uniprotkb:Q9P0W7|uniprotkb:Q96HF3|uniprotkb:Q8WX30|uniprotkb:Q9H0X0|ensembl:ENSP00000377176 psi-mi:bni3l_human(display_long)|uniprotkb:NIP3-like protein X(gene name synonym)|uniprotkb:BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A(gene name synonym)|uniprotkb:Adenovirus E1B19K-binding protein B5(gene name synonym)|uniprotkb:BNIP3L(gene name)|psi-mi:BNIP3L(display_short)|uniprotkb:BNIP3A(gene name synonym)|uniprotkb:BNIP3H(gene name synonym)|uniprotkb:NIX(gene name synonym) psi-mi:spat7_human(display_long)|uniprotkb:HSD-3.1(gene name synonym)|uniprotkb:HSD3(gene name synonym)|uniprotkb:Spermatogenesis-associated protein HSD3(gene name synonym)|uniprotkb:SPATA7(gene name)|psi-mi:SPATA7(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476634|imex:IM-26985-305 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004322.1|ensembl:ENSP00000370003|ensembl:ENST00000518611|ensembl:ENSP00000429851|ensembl:ENST00000520409|ensembl:ENSP00000428597|ensembl:ENST00000523515|ensembl:ENSP00000429698|dip:DIP-35187N|refseq:NP_001317420.1|ensembl:ENSG00000104765(gene)|ensembl:ENST00000380629(transcript)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016607"(nuclear speck)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0035694"(mitochondrial protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0051607"(defense response to virus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|interpro:IPR010548(BNIP3)|mint:O60238|reactome:R-HSA-6803204 refseq:NP_001035518.1|refseq:NP_060888.2|ensembl:ENSG00000042317(gene)|ensembl:ENST00000393545(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0007601"(visual perception)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0036064"(ciliary basal body)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0050896"(response to stimulus)|go:"GO:0120200"(rod photoreceptor outer segment)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903546"(protein localization to photoreceptor outer segment)|go:"GO:1903621"(protein localization to photoreceptor connecting cilium)|interpro:IPR029357|mint:Q9P0W8 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:GPDlK/z2VOVzJspIhN8XNFPSVMo9606 rogid:g+djqWT3cKjfCPnHVufeoKm9dYM9606 rigid:B3QrLGZhSEw2pTkCzm4azljLUxg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60238 uniprotkb:O43464 intact:EBI-849893|uniprotkb:Q5JW63|uniprotkb:Q8NF87|uniprotkb:B0AZS9|intact:EBI-28977676|ensembl:ENSP00000370003 intact:EBI-517086|uniprotkb:Q9HBZ4|uniprotkb:Q9P0Y3|uniprotkb:Q9P0Y4|ensembl:ENSP00000258080 psi-mi:bni3l_human(display_long)|uniprotkb:NIP3-like protein X(gene name synonym)|uniprotkb:BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A(gene name synonym)|uniprotkb:Adenovirus E1B19K-binding protein B5(gene name synonym)|uniprotkb:BNIP3L(gene name)|psi-mi:BNIP3L(display_short)|uniprotkb:BNIP3A(gene name synonym)|uniprotkb:BNIP3H(gene name synonym)|uniprotkb:NIX(gene name synonym) psi-mi:htra2_human(display_long)|uniprotkb:High temperature requirement protein A2(gene name synonym)|uniprotkb:Omi stress-regulated endoprotease(gene name synonym)|uniprotkb:Serine proteinase OMI(gene name synonym)|uniprotkb:Serine protease 25(gene name synonym)|uniprotkb:HTRA2(gene name)|psi-mi:HTRA2(display_short)|uniprotkb:PRSS25(gene name synonym)|uniprotkb:OMI(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476634|imex:IM-26985-305 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004322.1|ensembl:ENSP00000370003|ensembl:ENST00000518611|ensembl:ENSP00000429851|ensembl:ENST00000520409|ensembl:ENSP00000428597|ensembl:ENST00000523515|ensembl:ENSP00000429698|dip:DIP-35187N|refseq:NP_001317420.1|ensembl:ENSG00000104765(gene)|ensembl:ENST00000380629(transcript)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016607"(nuclear speck)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0035694"(mitochondrial protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0051607"(defense response to virus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|interpro:IPR010548(BNIP3)|mint:O60238|reactome:R-HSA-6803204 refseq:NP_037379.1|refseq:NP_659540.1|refseq:NP_001308656.1|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1904924"(negative regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:1905370"(serine-type endopeptidase complex)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001269"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001940(Peptidase S1C, HrtA/DegP2/Q/S)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR036034|interpro:IPR041489|mint:O43464|rcsb pdb:1LCY|rcsb pdb:2PZD|rcsb pdb:5FHT|rcsb pdb:5M3N|rcsb pdb:5M3O|rcsb pdb:5TNY|ensembl:ENSG00000115317(gene)|ensembl:ENST00000258080(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006508"(proteolysis)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007568"(aging)|go:"GO:0007628"(adult walking behavior)|go:"GO:0008233"(peptidase activity)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009635"(response to herbicide)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010822"(positive regulation of mitochondrion organization)|go:"GO:0012501"(programmed cell death)|go:"GO:0016020"(membrane)|go:"GO:0016540"(protein autoprocessing)|go:"GO:0019742"(pentacyclic triterpenoid metabolic process)|go:"GO:0030900"(forebrain development)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0048666"(neuron development)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0071300"(cellular response to retinoic acid)|rcsb pdb:5TNZ|rcsb pdb:5TO0|rcsb pdb:5TO1|rcsb pdb:5WYN - - comment:"author score: 30" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:GPDlK/z2VOVzJspIhN8XNFPSVMo9606 rogid:IaLYfoH7H9K64U0KrEY7iB1vAfU9606 rigid:B3QrLGZhSEw2pTkCzm4azljLUxg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60238 uniprotkb:Q96IX5 intact:EBI-849893|uniprotkb:Q5JW63|uniprotkb:Q8NF87|uniprotkb:B0AZS9|intact:EBI-28977676|ensembl:ENSP00000370003 intact:EBI-954033|ensembl:ENSP00000311245|ensembl:ENSP00000337705|ensembl:ENSP00000358826|ensembl:ENSP00000358830|ensembl:ENSP00000358840|uniprotkb:B2R4N2|uniprotkb:D3DR92 psi-mi:bni3l_human(display_long)|uniprotkb:NIP3-like protein X(gene name synonym)|uniprotkb:BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A(gene name synonym)|uniprotkb:Adenovirus E1B19K-binding protein B5(gene name synonym)|uniprotkb:BNIP3L(gene name)|psi-mi:BNIP3L(display_short)|uniprotkb:BNIP3A(gene name synonym)|uniprotkb:BNIP3H(gene name synonym)|uniprotkb:NIX(gene name synonym) psi-mi:atpmk_human(display_long)|uniprotkb:ATP5MK(gene name)|psi-mi:ATP5MK(display_short)|uniprotkb:ATP synthase membrane subunit DAPIT, mitochondrial(gene name synonym)|uniprotkb:ATP5MD(gene name synonym)|uniprotkb:DAPIT(gene name synonym)|uniprotkb:Diabetes-associated protein in insulin-sensitive tissues(gene name synonym)|uniprotkb:HCV F-transactivated protein 2(gene name synonym)|uniprotkb:HCVFTP2(gene name synonym)|uniprotkb:USMG5(gene name synonym)|uniprotkb:Up-regulated during skeletal muscle growth protein 5(gene name synonym)|uniprotkb:PD04912(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476634|imex:IM-26985-305 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004322.1|ensembl:ENSP00000370003|ensembl:ENST00000518611|ensembl:ENSP00000429851|ensembl:ENST00000520409|ensembl:ENSP00000428597|ensembl:ENST00000523515|ensembl:ENSP00000429698|dip:DIP-35187N|refseq:NP_001317420.1|ensembl:ENSG00000104765(gene)|ensembl:ENST00000380629(transcript)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016607"(nuclear speck)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0035694"(mitochondrial protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0051607"(defense response to virus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|interpro:IPR010548(BNIP3)|mint:O60238|reactome:R-HSA-6803204 ensembl:ENSG00000173915(gene)|ensembl:ENST00000309579(transcript)|ensembl:ENST00000337003(transcript)|ensembl:ENST00000369811(transcript)|ensembl:ENST00000369815(transcript)|ensembl:ENST00000369825(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0016021"(integral component of membrane)|interpro:IPR009125(DAPIT)|mint:Q96IX5|refseq:NP_001193355.1|refseq:NP_001193356.1|refseq:NP_116136.1 - - comment:"author score: 32" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:GPDlK/z2VOVzJspIhN8XNFPSVMo9606 rogid:7ClNWlgeH39kD7E6oiQdkuj7Hag9606 rigid:B3QrLGZhSEw2pTkCzm4azljLUxg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60238 uniprotkb:Q12983 intact:EBI-849893|uniprotkb:Q5JW63|uniprotkb:Q8NF87|uniprotkb:B0AZS9|intact:EBI-28977676|ensembl:ENSP00000370003 intact:EBI-749464|uniprotkb:O14620|uniprotkb:Q96GP0|intact:EBI-28978130|ensembl:ENSP00000357625 psi-mi:bni3l_human(display_long)|uniprotkb:NIP3-like protein X(gene name synonym)|uniprotkb:BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A(gene name synonym)|uniprotkb:Adenovirus E1B19K-binding protein B5(gene name synonym)|uniprotkb:BNIP3L(gene name)|psi-mi:BNIP3L(display_short)|uniprotkb:BNIP3A(gene name synonym)|uniprotkb:BNIP3H(gene name synonym)|uniprotkb:NIX(gene name synonym) psi-mi:bnip3_human(display_long)|uniprotkb:BNIP3(gene name)|psi-mi:BNIP3(display_short)|uniprotkb:NIP3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476634|imex:IM-26985-305 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004322.1|ensembl:ENSP00000370003|ensembl:ENST00000518611|ensembl:ENSP00000429851|ensembl:ENST00000520409|ensembl:ENSP00000428597|ensembl:ENST00000523515|ensembl:ENSP00000429698|dip:DIP-35187N|refseq:NP_001317420.1|ensembl:ENSG00000104765(gene)|ensembl:ENST00000380629(transcript)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016607"(nuclear speck)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0035694"(mitochondrial protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0051607"(defense response to virus)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|interpro:IPR010548(BNIP3)|mint:O60238|reactome:R-HSA-6803204 ensembl:ENSP00000357625|refseq:NP_004043.3|dip:DIP-34429N|ensembl:ENSG00000176171(gene)|ensembl:ENST00000368636(transcript)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006915"(apoptotic process)|go:"GO:0008219"(cell death)|go:"GO:0009617"(response to bacterium)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010637"(negative regulation of mitochondrial fusion)|go:"GO:0010659"(cardiac muscle cell apoptotic process)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0010917"(negative regulation of mitochondrial membrane potential)|go:"GO:0010940"(positive regulation of necrotic cell death)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030425"(dendrite)|go:"GO:0031307"(integral component of mitochondrial outer membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0035694"(mitochondrial protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043067"(regulation of programmed cell death)|go:"GO:0043068"(positive regulation of programmed cell death)|go:"GO:0043243"(positive regulation of protein-containing complex disassembly)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045837"(negative regulation of membrane potential)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0048102"(autophagic cell death)|go:"GO:0048678"(response to axon injury)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0051020"(GTPase binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051561"(positive regulation of mitochondrial calcium ion concentration)|go:"GO:0051607"(defense response to virus)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071279"(cellular response to cobalt ion)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090649"(response to oxygen-glucose deprivation)|go:"GO:0097345"(mitochondrial outer membrane permeabilization)|go:"GO:0140507"(granzyme-mediated programmed cell death signaling pathway)|go:"GO:1901998"(toxin transport)|go:"GO:1902109"(negative regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1990144"(intrinsic apoptotic signaling pathway in response to hypoxia)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR010548(BNIP3)|mint:Q12983|rcsb pdb:2J5D|rcsb pdb:2KA1|rcsb pdb:2KA2 - - crc64:53967696EDA005E2|comment:"author score: 44" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:GPDlK/z2VOVzJspIhN8XNFPSVMo9606 rogid:f+opYD7xO+AbYqLXXC5wh4ZJqIE9606 rigid:B3QrLGZhSEw2pTkCzm4azljLUxg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UIF9 uniprotkb:P81605 intact:EBI-934890|uniprotkb:O00536|uniprotkb:O15030|uniprotkb:Q96H26|uniprotkb:B3KN66|uniprotkb:Q68DI8|ensembl:ENSP00000446880 intact:EBI-395625|uniprotkb:P58461|uniprotkb:A5JHP2|uniprotkb:A5JHP3|uniprotkb:Q53YJ2|ensembl:ENSP00000293371 psi-mi:baz2a_human(display_long)|uniprotkb:BAZ2A(gene name)|psi-mi:BAZ2A(display_short)|uniprotkb:KIAA0314(gene name synonym)|uniprotkb:TIP5(gene name synonym)|uniprotkb:Transcription termination factor I-interacting protein 5(gene name synonym)|uniprotkb:hWALp3(gene name synonym) psi-mi:dcd_human(display_long)|uniprotkb:AIDD(gene name synonym)|uniprotkb:DSEP(gene name synonym)|uniprotkb:Preproteolysin(gene name synonym)|uniprotkb:DCD(gene name)|psi-mi:DCD(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476529|imex:IM-26985-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_038477.2|ensembl:ENSG00000076108(gene)|ensembl:ENST00000551812(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0042393"(histone binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070577"(lysine-acetylated histone binding)|interpro:IPR001487(Bromodomain)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR017956|interpro:IPR018359|interpro:IPR018501|interpro:IPR019787|interpro:IPR028940|interpro:IPR028941|interpro:IPR028942|interpro:IPR036427|interpro:IPR037374|mint:Q9UIF9|rcsb pdb:4LZ2|rcsb pdb:4Q6F|rcsb pdb:4QBM|rcsb pdb:4QF2|rcsb pdb:5AGQ|rcsb pdb:5MGJ|rcsb pdb:5MGK|rcsb pdb:5MGL|rcsb pdb:5MGM|rcsb pdb:5OR8|rcsb pdb:5T8R|rcsb pdb:6FAP|rcsb pdb:6FG6|rcsb pdb:6FGF|rcsb pdb:6FGG|rcsb pdb:6FGH|rcsb pdb:6FGI|rcsb pdb:6FGL|rcsb pdb:6FGV|rcsb pdb:6FGW|rcsb pdb:6FHU|rcsb pdb:6FI0|rcsb pdb:6FKP|reactome:R-HSA-427413 refseq:NP_444513.1|refseq:NP_001287783.1|ensembl:ENSG00000161634(gene)|ensembl:ENST00000293371(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008233"(peptidase activity)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR028130|interpro:IPR043557|mint:P81605|rcsb pdb:2KSG|rcsb pdb:2NDK|rcsb pdb:2YMK|rcsb pdb:6SHK|reactome:R-HSA-6803157 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:KfCpUyqOdz/VMjAKhvKyV9Ft1vs9606 rogid:M8PkKVWx98nhtd79ods05mqw8Ls9606 rigid:3iWJ2kwY9TwCp61sC6espckGMr8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UIF9 uniprotkb:Q01469 intact:EBI-934890|uniprotkb:O00536|uniprotkb:O15030|uniprotkb:Q96H26|uniprotkb:B3KN66|uniprotkb:Q68DI8|ensembl:ENSP00000446880 intact:EBI-1054073|uniprotkb:B2R4K0|ensembl:ENSP00000297258 psi-mi:baz2a_human(display_long)|uniprotkb:BAZ2A(gene name)|psi-mi:BAZ2A(display_short)|uniprotkb:KIAA0314(gene name synonym)|uniprotkb:TIP5(gene name synonym)|uniprotkb:Transcription termination factor I-interacting protein 5(gene name synonym)|uniprotkb:hWALp3(gene name synonym) psi-mi:fabp5_human(display_long)|uniprotkb:Epidermal-type fatty acid-binding protein(gene name synonym)|uniprotkb:Psoriasis-associated fatty acid-binding protein homolog(gene name synonym)|uniprotkb:FABP5(gene name)|psi-mi:FABP5(display_short)|uniprotkb:Fatty acid-binding protein, epidermal(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476529|imex:IM-26985-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_038477.2|ensembl:ENSG00000076108(gene)|ensembl:ENST00000551812(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0042393"(histone binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070577"(lysine-acetylated histone binding)|interpro:IPR001487(Bromodomain)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR017956|interpro:IPR018359|interpro:IPR018501|interpro:IPR019787|interpro:IPR028940|interpro:IPR028941|interpro:IPR028942|interpro:IPR036427|interpro:IPR037374|mint:Q9UIF9|rcsb pdb:4LZ2|rcsb pdb:4Q6F|rcsb pdb:4QBM|rcsb pdb:4QF2|rcsb pdb:5AGQ|rcsb pdb:5MGJ|rcsb pdb:5MGK|rcsb pdb:5MGL|rcsb pdb:5MGM|rcsb pdb:5OR8|rcsb pdb:5T8R|rcsb pdb:6FAP|rcsb pdb:6FG6|rcsb pdb:6FGF|rcsb pdb:6FGG|rcsb pdb:6FGH|rcsb pdb:6FGI|rcsb pdb:6FGL|rcsb pdb:6FGV|rcsb pdb:6FGW|rcsb pdb:6FHU|rcsb pdb:6FI0|rcsb pdb:6FKP|reactome:R-HSA-427413 refseq:NP_001435.1|ensembl:ENSG00000164687(gene)|ensembl:ENST00000297258(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0008289"(lipid binding)|go:"GO:0008544"(epidermis development)|go:"GO:0010829"(negative regulation of glucose transmembrane transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031392"(regulation of prostaglandin biosynthetic process)|go:"GO:0035360"(positive regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099178"(regulation of retrograde trans-synaptic signaling by endocanabinoid)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990379"(lipid transport across blood-brain barrier)|interpro:IPR000463(Cytosolic fatty-acid binding)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR012674(Calycin)|interpro:IPR031259|mint:Q01469|rcsb pdb:1B56|rcsb pdb:1JJJ|rcsb pdb:4AZM|rcsb pdb:4AZR|rcsb pdb:4LKP|rcsb pdb:4LKT|rcsb pdb:5HZ5|rcsb pdb:5UR9|reactome:R-HSA-163560|reactome:R-HSA-5362517|reactome:R-HSA-6798695 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:KfCpUyqOdz/VMjAKhvKyV9Ft1vs9606 rogid:vxp81/mezHcm5oo27QOmAM8Y5dI9606 rigid:3iWJ2kwY9TwCp61sC6espckGMr8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UIF9 uniprotkb:P24539 intact:EBI-934890|uniprotkb:O00536|uniprotkb:O15030|uniprotkb:Q96H26|uniprotkb:B3KN66|uniprotkb:Q68DI8|ensembl:ENSP00000446880 intact:EBI-1044810|uniprotkb:Q9BQ68|uniprotkb:Q9BRU8|ensembl:ENSP00000358737 psi-mi:baz2a_human(display_long)|uniprotkb:BAZ2A(gene name)|psi-mi:BAZ2A(display_short)|uniprotkb:KIAA0314(gene name synonym)|uniprotkb:TIP5(gene name synonym)|uniprotkb:Transcription termination factor I-interacting protein 5(gene name synonym)|uniprotkb:hWALp3(gene name synonym) psi-mi:at5f1_human(display_long)|uniprotkb:ATP5PB(gene name)|psi-mi:ATP5PB(display_short)|uniprotkb:ATP synthase peripheral stalk-membrane subunit b(gene name synonym)|uniprotkb:"ATP synthase proton-transporting mitochondrial F(0) complex subunit B1"(gene name synonym)|uniprotkb:ATP synthase subunit b(gene name synonym)|uniprotkb:ATP5F1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476529|imex:IM-26985-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_038477.2|ensembl:ENSG00000076108(gene)|ensembl:ENST00000551812(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0042393"(histone binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070577"(lysine-acetylated histone binding)|interpro:IPR001487(Bromodomain)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR017956|interpro:IPR018359|interpro:IPR018501|interpro:IPR019787|interpro:IPR028940|interpro:IPR028941|interpro:IPR028942|interpro:IPR036427|interpro:IPR037374|mint:Q9UIF9|rcsb pdb:4LZ2|rcsb pdb:4Q6F|rcsb pdb:4QBM|rcsb pdb:4QF2|rcsb pdb:5AGQ|rcsb pdb:5MGJ|rcsb pdb:5MGK|rcsb pdb:5MGL|rcsb pdb:5MGM|rcsb pdb:5OR8|rcsb pdb:5T8R|rcsb pdb:6FAP|rcsb pdb:6FG6|rcsb pdb:6FGF|rcsb pdb:6FGG|rcsb pdb:6FGH|rcsb pdb:6FGI|rcsb pdb:6FGL|rcsb pdb:6FGV|rcsb pdb:6FGW|rcsb pdb:6FHU|rcsb pdb:6FI0|rcsb pdb:6FKP|reactome:R-HSA-427413 refseq:NP_001679.2|ensembl:ENSG00000116459(gene)|ensembl:ENST00000369722(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0021762"(substantia nigra development)|interpro:IPR008688(ATPase, F0 complex, subunit B, mitochondrial)|interpro:IPR013837(ATPase, F0 complex subunit B, mitochondrial, metazoa)|mint:P24539|reactome:R-HSA-163210|reactome:R-HSA-8949613|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport) - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:KfCpUyqOdz/VMjAKhvKyV9Ft1vs9606 rogid:n1HuorsLzONcID7ccOL9qEsODLE9606 rigid:3iWJ2kwY9TwCp61sC6espckGMr8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UIF9 uniprotkb:P01040 intact:EBI-934890|uniprotkb:O00536|uniprotkb:O15030|uniprotkb:Q96H26|uniprotkb:B3KN66|uniprotkb:Q68DI8|ensembl:ENSP00000446880 intact:EBI-724303|ensembl:ENSP00000264474|uniprotkb:Q6IB90 psi-mi:baz2a_human(display_long)|uniprotkb:BAZ2A(gene name)|psi-mi:BAZ2A(display_short)|uniprotkb:KIAA0314(gene name synonym)|uniprotkb:TIP5(gene name synonym)|uniprotkb:Transcription termination factor I-interacting protein 5(gene name synonym)|uniprotkb:hWALp3(gene name synonym) psi-mi:cyta_human(display_long)|uniprotkb:Cystatin-AS(gene name synonym)|uniprotkb:Stefin-A(gene name synonym)|uniprotkb:CSTA(gene name)|psi-mi:CSTA(display_short)|uniprotkb:STF1(gene name synonym)|uniprotkb:STFA(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476529|imex:IM-26985-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_038477.2|ensembl:ENSG00000076108(gene)|ensembl:ENST00000551812(transcript)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0042393"(histone binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070577"(lysine-acetylated histone binding)|interpro:IPR001487(Bromodomain)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR017956|interpro:IPR018359|interpro:IPR018501|interpro:IPR019787|interpro:IPR028940|interpro:IPR028941|interpro:IPR028942|interpro:IPR036427|interpro:IPR037374|mint:Q9UIF9|rcsb pdb:4LZ2|rcsb pdb:4Q6F|rcsb pdb:4QBM|rcsb pdb:4QF2|rcsb pdb:5AGQ|rcsb pdb:5MGJ|rcsb pdb:5MGK|rcsb pdb:5MGL|rcsb pdb:5MGM|rcsb pdb:5OR8|rcsb pdb:5T8R|rcsb pdb:6FAP|rcsb pdb:6FG6|rcsb pdb:6FGF|rcsb pdb:6FGG|rcsb pdb:6FGH|rcsb pdb:6FGI|rcsb pdb:6FGL|rcsb pdb:6FGV|rcsb pdb:6FGW|rcsb pdb:6FHU|rcsb pdb:6FI0|rcsb pdb:6FKP|reactome:R-HSA-427413 refseq:NP_005204.1|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR001713(Proteinase inhibitor I25A, stefin A)|mint:P01040|rcsb pdb:1CYU|rcsb pdb:1CYV|rcsb pdb:1DVC|rcsb pdb:1DVD|rcsb pdb:1GD3|rcsb pdb:1GD4|rcsb pdb:1N9J|rcsb pdb:1NB3|rcsb pdb:1NB5|rcsb pdb:3K9M|rcsb pdb:3KFQ|interpro:IPR018073|rcsb pdb:3KSE|reactome:R-HSA-6809371|ensembl:ENSG00000121552(gene)|ensembl:ENST00000264474(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002020"(protease binding)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0045861"(negative regulation of proteolysis) - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:KfCpUyqOdz/VMjAKhvKyV9Ft1vs9606 rogid:SzbpyWUHlOtItIvffzuwhcqFsDI9606 rigid:3iWJ2kwY9TwCp61sC6espckGMr8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P38398 uniprotkb:Q8NEY8 intact:EBI-349905|uniprotkb:Q3LRJ0|uniprotkb:O15129|uniprotkb:Q7KYU9|ensembl:ENSP00000350283|uniprotkb:E9PFZ0|uniprotkb:Q3LRJ6|uniprotkb:Q6IN79|uniprotkb:Q1RMC1 intact:EBI-474076|uniprotkb:Q86YT2|uniprotkb:Q8IXN3|uniprotkb:Q8TB09|uniprotkb:Q96NB9|uniprotkb:Q9NXL4|uniprotkb:Q9P0P6|uniprotkb:Q9P0R9|uniprotkb:E9PAX8|ensembl:ENSP00000378935|ensembl:ENSP00000479913 psi-mi:brca1_human(display_long)|uniprotkb:BRCA1(gene name)|psi-mi:BRCA1(display_short)|uniprotkb:RNF53(gene name synonym)|uniprotkb:RING finger protein 53(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BRCA1(gene name synonym) psi-mi:pphln_human(display_long)|uniprotkb:Gastric cancer antigen Ga50(gene name synonym)|uniprotkb:HSPC206(orf name)|uniprotkb:HSPC232(orf name)|uniprotkb:PPHLN1(gene name)|psi-mi:PPHLN1(display_short)|uniprotkb:CDC7 expression repressor(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476655|imex:IM-26985-147 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009225.1|refseq:NP_009228.2|refseq:NP_009229.2|refseq:NP_009231.2|ensembl:ENSG00000012048(gene)|ensembl:ENST00000357654(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000800"(lateral element)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006301"(postreplication repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015631"(tubulin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031436"(BRCA1-BARD1 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0043627"(response to estrogen)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070512"(positive regulation of histone H4-K20 methylation)|go:"GO:0070531"(BRCA1-A complex)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR001357(BRCT)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011364(BRCA1)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR025994|interpro:IPR031099|interpro:IPR036420|mint:P38398|rcsb pdb:1JM7|rcsb pdb:1JNX|rcsb pdb:1N5O|rcsb pdb:1OQA|rcsb pdb:1T15|rcsb pdb:1T29|rcsb pdb:1T2U|rcsb pdb:1T2V|rcsb pdb:1Y98|rcsb pdb:2ING|rcsb pdb:3COJ|rcsb pdb:3K0H|rcsb pdb:3K0K|rcsb pdb:3K15|rcsb pdb:3K16|rcsb pdb:3PXA|rcsb pdb:3PXB|rcsb pdb:3PXC|rcsb pdb:3PXD|rcsb pdb:3PXE|rcsb pdb:4IFI|rcsb pdb:4IGK|rcsb pdb:4JLU|rcsb pdb:4OFB|rcsb pdb:4U4A|rcsb pdb:4Y18|rcsb pdb:4Y2G|rcsb pdb:6G2I|reactome:R-HSA-1221632|reactome:R-HSA-3108214|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5689901|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6796648|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-8953750|reactome:R-HSA-912446|reactome:R-HSA-9663199|reactome:R-HSA-9699150|refseq:NP_009230.2|dip:DIP-5971N refseq:NP_001137259.1|refseq:NP_001137260.1|refseq:NP_057572.5|refseq:NP_958846.1|refseq:NP_958847.1|refseq:NP_958848.1|refseq:NP_958923.1|dip:DIP-49051N|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0031424"(keratinization)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0097355"(protein localization to heterochromatin)|interpro:IPR028851|mint:Q8NEY8|rcsb pdb:6SWG|ensembl:ENSG00000134283(gene)|ensembl:ENST00000395568(transcript)|ensembl:ENST00000610488(transcript) - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Tx+5uS8dERqc0lhPZ0ZIKQaifXM9606 rogid:+s8KstGQ7d91qe3DDnpKYMJon7o9606 rigid:i46tpLbzvyuqFtpAR6SaME1gpcc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P38398 uniprotkb:Q92734 intact:EBI-349905|uniprotkb:Q3LRJ0|uniprotkb:O15129|uniprotkb:Q7KYU9|ensembl:ENSP00000350283|uniprotkb:E9PFZ0|uniprotkb:Q3LRJ6|uniprotkb:Q6IN79|uniprotkb:Q1RMC1 intact:EBI-357061|uniprotkb:Q15656|intact:EBI-357314|uniprotkb:Q969I2|uniprotkb:D3DN49|uniprotkb:K0J5S8|uniprotkb:K0J6K2|intact:EBI-28969365|ensembl:ENSP00000240851|ensembl:ENSP00000419960|ensembl:ENSP00000420797|ensembl:ENSP00000501815|ensembl:ENSP00000502071|ensembl:ENSP00000502450|ensembl:ENSP00000502592|ensembl:ENSP00000502734|uniprotkb:G5E9V1 psi-mi:brca1_human(display_long)|uniprotkb:BRCA1(gene name)|psi-mi:BRCA1(display_short)|uniprotkb:RNF53(gene name synonym)|uniprotkb:RING finger protein 53(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BRCA1(gene name synonym) psi-mi:tfg_human(display_long)|uniprotkb:TFG(gene name)|psi-mi:TFG(display_short)|uniprotkb:TRK-fused gene protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476655|imex:IM-26985-147 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009225.1|refseq:NP_009228.2|refseq:NP_009229.2|refseq:NP_009231.2|ensembl:ENSG00000012048(gene)|ensembl:ENST00000357654(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000800"(lateral element)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006301"(postreplication repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015631"(tubulin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031436"(BRCA1-BARD1 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0043627"(response to estrogen)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070512"(positive regulation of histone H4-K20 methylation)|go:"GO:0070531"(BRCA1-A complex)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR001357(BRCT)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011364(BRCA1)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR025994|interpro:IPR031099|interpro:IPR036420|mint:P38398|rcsb pdb:1JM7|rcsb pdb:1JNX|rcsb pdb:1N5O|rcsb pdb:1OQA|rcsb pdb:1T15|rcsb pdb:1T29|rcsb pdb:1T2U|rcsb pdb:1T2V|rcsb pdb:1Y98|rcsb pdb:2ING|rcsb pdb:3COJ|rcsb pdb:3K0H|rcsb pdb:3K0K|rcsb pdb:3K15|rcsb pdb:3K16|rcsb pdb:3PXA|rcsb pdb:3PXB|rcsb pdb:3PXC|rcsb pdb:3PXD|rcsb pdb:3PXE|rcsb pdb:4IFI|rcsb pdb:4IGK|rcsb pdb:4JLU|rcsb pdb:4OFB|rcsb pdb:4U4A|rcsb pdb:4Y18|rcsb pdb:4Y2G|rcsb pdb:6G2I|reactome:R-HSA-1221632|reactome:R-HSA-3108214|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5689901|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6796648|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-8953750|reactome:R-HSA-912446|reactome:R-HSA-9663199|reactome:R-HSA-9699150|refseq:NP_009230.2|dip:DIP-5971N refseq:NP_001007566.1|refseq:NP_001182407.1|refseq:NP_001182408.1|refseq:NP_006061.2|ensembl:ENSP00000240851|ensembl:ENST00000463568|ensembl:ENSP00000419504|ensembl:ENST00000476228|ensembl:ENSP00000417952|ensembl:ENSP00000420797|ensembl:ENSP00000419960|ensembl:ENST00000615993|ensembl:ENSP00000479269|ensembl:ENST00000620299|ensembl:ENSP00000479981|ensembl:ENSP00000502734|ensembl:ENST00000674645|ensembl:ENSP00000501892|ensembl:ENST00000674758|ensembl:ENSP00000502502|ensembl:ENST00000675047|ensembl:ENSP00000502497|ensembl:ENSP00000502592|ensembl:ENST00000675420|ensembl:ENSP00000502516|ensembl:ENSP00000502450|ensembl:ENST00000675543|ensembl:ENSP00000501815|ensembl:ENST00000675586|ensembl:ENSP00000502329|ensembl:ENST00000676111|ensembl:ENSP00000502139|ensembl:ENST00000676308|ensembl:ENSP00000502697|ensembl:ENSP00000502071|ensembl:ENST00000676431|ensembl:ENSP00000502698|ensembl:ENSP00000502229|refseq:XP_006713535.1|refseq:XP_006713536.1|ensembl:ENSG00000114354(gene)|ensembl:ENST00000240851(transcript)|ensembl:ENST00000487505(transcript)|ensembl:ENST00000490574(transcript)|ensembl:ENST00000674615(transcript)|ensembl:ENST00000675243(transcript)|ensembl:ENST00000675499(transcript)|ensembl:ENST00000675553(transcript)|ensembl:ENST00000676395(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR033512|interpro:IPR034857|mint:Q92734|reactome:R-HSA-204005|refseq:XP_011510636.1|refseq:XP_005247123.1|refseq:XP_016861016.1|refseq:XP_016861017.1|refseq:XP_016861018.1|refseq:XP_016861019.1 - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Tx+5uS8dERqc0lhPZ0ZIKQaifXM9606 rogid:y7aghh0X3Ewgpzcx5h5nB+X2dII9606 rigid:i46tpLbzvyuqFtpAR6SaME1gpcc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P38398 uniprotkb:Q99728 intact:EBI-349905|uniprotkb:Q3LRJ0|uniprotkb:O15129|uniprotkb:Q7KYU9|ensembl:ENSP00000350283|uniprotkb:E9PFZ0|uniprotkb:Q3LRJ6|uniprotkb:Q6IN79|uniprotkb:Q1RMC1 intact:EBI-473181|ensembl:ENSP00000260947|uniprotkb:O43574|uniprotkb:Q53SS5|uniprotkb:F6MDH7|uniprotkb:F6MDH8|uniprotkb:F6MDH9 psi-mi:brca1_human(display_long)|uniprotkb:BRCA1(gene name)|psi-mi:BRCA1(display_short)|uniprotkb:RNF53(gene name synonym)|uniprotkb:RING finger protein 53(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BRCA1(gene name synonym) psi-mi:bard1_human(display_long)|uniprotkb:BARD1(gene name)|psi-mi:BARD1(display_short)|uniprotkb:RING-type E3 ubiquitin transferase BARD1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476655|imex:IM-26985-147 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009225.1|refseq:NP_009228.2|refseq:NP_009229.2|refseq:NP_009231.2|ensembl:ENSG00000012048(gene)|ensembl:ENST00000357654(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000800"(lateral element)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006301"(postreplication repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015631"(tubulin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031436"(BRCA1-BARD1 complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0043627"(response to estrogen)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070512"(positive regulation of histone H4-K20 methylation)|go:"GO:0070531"(BRCA1-A complex)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0085020"(protein K6-linked ubiquitination)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|go:"GO:2000620"(positive regulation of histone H4-K16 acetylation)|interpro:IPR001357(BRCT)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011364(BRCA1)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018957|interpro:IPR025994|interpro:IPR031099|interpro:IPR036420|mint:P38398|rcsb pdb:1JM7|rcsb pdb:1JNX|rcsb pdb:1N5O|rcsb pdb:1OQA|rcsb pdb:1T15|rcsb pdb:1T29|rcsb pdb:1T2U|rcsb pdb:1T2V|rcsb pdb:1Y98|rcsb pdb:2ING|rcsb pdb:3COJ|rcsb pdb:3K0H|rcsb pdb:3K0K|rcsb pdb:3K15|rcsb pdb:3K16|rcsb pdb:3PXA|rcsb pdb:3PXB|rcsb pdb:3PXC|rcsb pdb:3PXD|rcsb pdb:3PXE|rcsb pdb:4IFI|rcsb pdb:4IGK|rcsb pdb:4JLU|rcsb pdb:4OFB|rcsb pdb:4U4A|rcsb pdb:4Y18|rcsb pdb:4Y2G|rcsb pdb:6G2I|reactome:R-HSA-1221632|reactome:R-HSA-3108214|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5689901|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6796648|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-8953750|reactome:R-HSA-912446|reactome:R-HSA-9663199|reactome:R-HSA-9699150|refseq:NP_009230.2|dip:DIP-5971N ensembl:ENSG00000138376(gene)|ensembl:ENST00000260947(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016607"(nuclear speck)|go:"GO:0019900"(kinase binding)|go:"GO:0031436"(BRCA1-BARD1 complex)|go:"GO:0031441"(negative regulation of mRNA 3'-end processing)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|refseq:NP_001269472.1|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070531"(BRCA1-A complex)|go:"GO:0085020"(protein K6-linked ubiquitination)|interpro:IPR001357(BRCT)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR002110(Ankyrin)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR020683|interpro:IPR036420|interpro:IPR036770|interpro:IPR039503|mint:Q99728|rcsb pdb:1JM7|rcsb pdb:2NTE|rcsb pdb:2R1Z|rcsb pdb:3C5R|rcsb pdb:3FA2|rcsb pdb:6M14|rcsb pdb:7E8I|rcsb pdb:7JZV|rcsb pdb:7LYC|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5689603|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-9663199|reactome:R-HSA-9699150|reactome:R-HSA-5693554|refseq:NP_000456.2|dip:DIP-5972N - - comment:"author score: 28" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Tx+5uS8dERqc0lhPZ0ZIKQaifXM9606 rogid:5dT1T3GUceuvwPpiTv5QW/QEDgE9606 rigid:i46tpLbzvyuqFtpAR6SaME1gpcc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUZ0 uniprotkb:Q68CP9 intact:EBI-7850114|intact:EBI-28969068|ensembl:ENSP00000215115|uniprotkb:Q6PD89|uniprotkb:O43770|intact:MINT-4535839 intact:EBI-637818|uniprotkb:Q15KG9|uniprotkb:Q5EB51|uniprotkb:Q645I3|uniprotkb:Q6ZRY5|uniprotkb:Q7Z3I5|uniprotkb:Q86T28|uniprotkb:Q96SJ6|uniprotkb:Q9HCL5|ensembl:ENSP00000335044 psi-mi:bcl7c_human(display_long)|uniprotkb:BCL7C(gene name)|psi-mi:BCL7C(display_short) psi-mi:arid2_human(display_long)|uniprotkb:BRG1-associated factor 200(gene name synonym)|uniprotkb:Zinc finger protein with activation potential(gene name synonym)|uniprotkb:Zipzap/p200(gene name synonym)|uniprotkb:ARID2(gene name)|psi-mi:ARID2(display_short)|uniprotkb:KIAA1557(gene name synonym)|uniprotkb:BAF200(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476547|imex:IM-26985-531 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001273455.1|ensembl:ENSP00000215115|ensembl:ENST00000380317|ensembl:ENSP00000369674|ensembl:ENSG00000099385(gene)|ensembl:ENST00000215115(transcript)|go:"GO:0006915"(apoptotic process)|interpro:IPR006804(BCL7, N-terminal)|mint:Q8WUZ0|refseq:NP_004756.2 refseq:NP_689854.2|ensembl:ENSG00000189079(gene)|ensembl:ENST00000334344(transcript)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042592"(homeostatic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048568"(embryonic organ development)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003150(DNA-binding RFX)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR036388|interpro:IPR036390|interpro:IPR036431|mint:Q68CP9|reactome:R-HSA-3214858|reactome:R-HSA-8939243|dip:DIP-33391N|refseq:NP_001334768.1|ensembl:ENSP00000335044 - comment:mint|comment:homomint|function:May play an anti-apoptotic role comment:"author score: 70" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:XuyDhxOhWHNVXmgi/WXLmCvKn409606 rogid:7AJ6PqICERVZS+s3sZBIBODzs/I9606 rigid:3fK9ES0QT5FEfdhSyeOzdmQEIDU false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUZ0 uniprotkb:Q86U86 intact:EBI-7850114|intact:EBI-28969068|ensembl:ENSP00000215115|uniprotkb:Q6PD89|uniprotkb:O43770|intact:MINT-4535839 intact:EBI-637807|uniprotkb:Q9H2T3|uniprotkb:Q9H2T4|uniprotkb:Q9H2T5|uniprotkb:Q9H301|uniprotkb:Q9H314|uniprotkb:A1L381|uniprotkb:A1L382|uniprotkb:A4FUJ7|uniprotkb:Q1RMD1|uniprotkb:Q1RMD2|uniprotkb:Q96MS2|ensembl:ENSP00000296302 psi-mi:bcl7c_human(display_long)|uniprotkb:BCL7C(gene name)|psi-mi:BCL7C(display_short) psi-mi:pb1_human(display_long)|uniprotkb:Polybromo-1D(gene name synonym)|uniprotkb:BRG1-associated factor 180(gene name synonym)|uniprotkb:PBRM1(gene name)|psi-mi:PBRM1(display_short)|uniprotkb:PB1(gene name synonym)|uniprotkb:BAF180(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476547|imex:IM-26985-531 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001273455.1|ensembl:ENSP00000215115|ensembl:ENST00000380317|ensembl:ENSP00000369674|ensembl:ENSG00000099385(gene)|ensembl:ENST00000215115(transcript)|go:"GO:0006915"(apoptotic process)|interpro:IPR006804(BCL7, N-terminal)|mint:Q8WUZ0|refseq:NP_004756.2 refseq:NP_060783.3|ensembl:ENSG00000163939(gene)|ensembl:ENST00000296302(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016586"(RSC-type complex)|go:"GO:0043044"|interpro:IPR001025(Bromo adjacent region)|interpro:IPR001487(Bromodomain)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR018359|interpro:IPR036427|interpro:IPR036910|interpro:IPR037382|interpro:IPR037968|interpro:IPR043151|mint:Q86U86|rcsb pdb:2KTB|rcsb pdb:3G0J|rcsb pdb:3HMF|rcsb pdb:3IU5|rcsb pdb:3IU6|rcsb pdb:3K2J|rcsb pdb:3LJW|rcsb pdb:3MB4|rcsb pdb:3TLP|rcsb pdb:4Q0N|rcsb pdb:4Q0O|rcsb pdb:4Y03|rcsb pdb:5E7D|rcsb pdb:5FH6|rcsb pdb:5FH7|rcsb pdb:5FH8|rcsb pdb:5HRV|rcsb pdb:5HRW|rcsb pdb:5HRX|rcsb pdb:5II1|rcsb pdb:5II2|rcsb pdb:5IID|rcsb pdb:6OXB|rcsb pdb:6ZN6|rcsb pdb:6ZNV|rcsb pdb:6ZS3|rcsb pdb:6ZS4|reactome:R-HSA-3214858|reactome:R-HSA-8939243|dip:DIP-33045N|refseq:XP_016862237.1|refseq:XP_016862238.1|refseq:XP_016862239.1|refseq:XP_016862246.1|refseq:XP_016862247.1|refseq:NP_851385.1 - comment:mint|comment:homomint|function:May play an anti-apoptotic role comment:"author score: 72" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:XuyDhxOhWHNVXmgi/WXLmCvKn409606 rogid:nJp9kwLE9qxj6DcyEO8dUok6k/Q9606 rigid:3fK9ES0QT5FEfdhSyeOzdmQEIDU false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUZ0 uniprotkb:Q8NFD5 intact:EBI-7850114|intact:EBI-28969068|ensembl:ENSP00000215115|uniprotkb:Q6PD89|uniprotkb:O43770|intact:MINT-4535839 intact:EBI-679921|uniprotkb:Q5JRD1|uniprotkb:Q5VYC4|uniprotkb:Q8IZY8|uniprotkb:Q8TEV0|uniprotkb:Q8TF02|uniprotkb:Q99491|uniprotkb:Q9ULI5|intact:EBI-2560572|ensembl:ENSP00000055163 psi-mi:bcl7c_human(display_long)|uniprotkb:BCL7C(gene name)|psi-mi:BCL7C(display_short) psi-mi:ari1b_human(display_long)|uniprotkb:BAF250B(gene name synonym)|uniprotkb:Osa homolog 2(gene name synonym)|uniprotkb:p250R(gene name synonym)|uniprotkb:BRG1-binding protein hELD/OSA1(gene name synonym)|uniprotkb:BRG1-associated factor 250b(gene name synonym)|uniprotkb:ARID1B(gene name)|psi-mi:ARID1B(display_short)|uniprotkb:DAN15(gene name synonym)|uniprotkb:KIAA1235(gene name synonym)|uniprotkb:OSA2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476547|imex:IM-26985-531 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001273455.1|ensembl:ENSP00000215115|ensembl:ENST00000380317|ensembl:ENSP00000369674|ensembl:ENSG00000099385(gene)|ensembl:ENST00000215115(transcript)|go:"GO:0006915"(apoptotic process)|interpro:IPR006804(BCL7, N-terminal)|mint:Q8WUZ0|refseq:NP_004756.2 refseq:NP_001333742.1|refseq:NP_059989.2|refseq:NP_065783.3|ensembl:ENSG00000049618(gene)|ensembl:ENST00000350026(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0035060"(brahma complex)|go:"GO:0043044"|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048096"|go:"GO:0071565"(nBAF complex)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR021906|interpro:IPR033388|interpro:IPR036431|interpro:IPR038040|mint:Q8NFD5|rcsb pdb:2CXY|rcsb pdb:2EH9|reactome:R-HSA-3214858|reactome:R-HSA-8939243 - comment:mint|comment:homomint|function:May play an anti-apoptotic role comment:"author score: 121" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:XuyDhxOhWHNVXmgi/WXLmCvKn409606 rogid:BeWhuwPk5f6HN+yasFEJRpkbM6A9606 rigid:3fK9ES0QT5FEfdhSyeOzdmQEIDU false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUZ0 uniprotkb:O14497 intact:EBI-7850114|intact:EBI-28969068|ensembl:ENSP00000215115|uniprotkb:Q6PD89|uniprotkb:O43770|intact:MINT-4535839 intact:EBI-637887|intact:EBI-28988406|ensembl:ENSP00000320485|uniprotkb:D3DPL1|uniprotkb:Q53FK9|uniprotkb:Q5T0W1|uniprotkb:Q5T0W2|uniprotkb:Q5T0W3|uniprotkb:Q8NFD6|uniprotkb:Q96T89|uniprotkb:Q9BY33|uniprotkb:Q9HBJ5|uniprotkb:Q9UPZ1 psi-mi:bcl7c_human(display_long)|uniprotkb:BCL7C(gene name)|psi-mi:BCL7C(display_short) psi-mi:ari1a_human(display_long)|uniprotkb:hELD(gene name synonym)|uniprotkb:SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1(gene name synonym)|uniprotkb:SWI/SNF complex protein p270(gene name synonym)|uniprotkb:B120(gene name synonym)|uniprotkb:SWI-like protein(gene name synonym)|uniprotkb:Osa homolog 1(gene name synonym)|uniprotkb:BRG1-associated factor 250(gene name synonym)|uniprotkb:BRG1-associated factor 250a(gene name synonym)|uniprotkb:ARID1A(gene name)|psi-mi:ARID1A(display_short)|uniprotkb:C1orf4(gene name synonym)|uniprotkb:SMARCF1(gene name synonym)|uniprotkb:OSA1(gene name synonym)|uniprotkb:BAF250(gene name synonym)|uniprotkb:BAF250A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476547|imex:IM-26985-531 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001273455.1|ensembl:ENSP00000215115|ensembl:ENST00000380317|ensembl:ENSP00000369674|ensembl:ENSG00000099385(gene)|ensembl:ENST00000215115(transcript)|go:"GO:0006915"(apoptotic process)|interpro:IPR006804(BCL7, N-terminal)|mint:Q8WUZ0|refseq:NP_004756.2 reactome:R-HSA-3214858|reactome:R-HSA-8939243|go:"GO:0005634"(nucleus)|ensembl:ENSG00000117713(gene)|go:"GO:0005654"(nucleoplasm)|ensembl:ENST00000324856(transcript)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0035060"(brahma complex)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043044"|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048096"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021906|interpro:IPR030094|interpro:IPR033388|interpro:IPR036431|mint:O14497|rcsb pdb:1RYU|rcsb pdb:6LTH|rcsb pdb:6LTJ|refseq:NP_006006.3|refseq:NP_624361.1|dip:DIP-33016N|ensembl:ENSP00000320485|ensembl:ENST00000374152|ensembl:ENSP00000363267|ensembl:ENST00000457599|ensembl:ENSP00000387636 - comment:mint|comment:homomint|function:May play an anti-apoptotic role comment:"author score: 176" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:XuyDhxOhWHNVXmgi/WXLmCvKn409606 rogid:C3ZRlsnBUZV6SBEbISRImamhzoQ9606 rigid:3fK9ES0QT5FEfdhSyeOzdmQEIDU false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUZ0 uniprotkb:P51531 intact:EBI-7850114|intact:EBI-28969068|ensembl:ENSP00000215115|uniprotkb:Q6PD89|uniprotkb:O43770|intact:MINT-4535839 intact:EBI-679562|uniprotkb:B1ALG3|uniprotkb:B1ALG4|uniprotkb:D3DRH4|uniprotkb:D3DRH5|ensembl:ENSP00000265773|ensembl:ENSP00000371638 psi-mi:bcl7c_human(display_long)|uniprotkb:BCL7C(gene name)|psi-mi:BCL7C(display_short) psi-mi:smca2_human(display_long)|uniprotkb:ATP-dependent helicase SMARCA2(gene name synonym)|uniprotkb:SNF2-alpha(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2(gene name synonym)|uniprotkb:SMARCA2(gene name)|psi-mi:SMARCA2(display_short)|uniprotkb:BRM(gene name synonym)|uniprotkb:SNF2A(gene name synonym)|uniprotkb:SNF2L2(gene name synonym)|uniprotkb:BAF190B(gene name synonym)|uniprotkb:Protein brahma homolog(gene name synonym)|uniprotkb:BRG1-associated factor 190B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476547|imex:IM-26985-531 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001273455.1|ensembl:ENSP00000215115|ensembl:ENST00000380317|ensembl:ENSP00000369674|ensembl:ENSG00000099385(gene)|ensembl:ENST00000215115(transcript)|go:"GO:0006915"(apoptotic process)|interpro:IPR006804(BCL7, N-terminal)|mint:Q8WUZ0|refseq:NP_004756.2 refseq:NP_003061.3|refseq:NP_620614.2|refseq:NP_001276325.1|refseq:NP_001276326.1|dip:DIP-29005N|ensembl:ENSG00000080503(gene)|ensembl:ENST00000349721(transcript)|ensembl:ENST00000382203(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007286"(spermatid development)|go:"GO:0007399"(nervous system development)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070615"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030088|interpro:IPR036427|interpro:IPR037259|interpro:IPR038718|mint:P51531|rcsb pdb:2DAT|rcsb pdb:4QY4|rcsb pdb:5DKC|rcsb pdb:5DKH|rcsb pdb:6EG2|rcsb pdb:6EG3|rcsb pdb:6HAX|rcsb pdb:6HAY|rcsb pdb:6HAZ|reactome:R-HSA-3214858|reactome:R-HSA-8939243 - comment:mint|comment:homomint|function:May play an anti-apoptotic role comment:"author score: 181" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:XuyDhxOhWHNVXmgi/WXLmCvKn409606 rogid:DmQot4h4SmtqmUGBgF5ictTah289606 rigid:3fK9ES0QT5FEfdhSyeOzdmQEIDU false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUZ0 uniprotkb:Q9C0A0 intact:EBI-7850114|intact:EBI-28969068|ensembl:ENSP00000215115|uniprotkb:Q6PD89|uniprotkb:O43770|intact:MINT-4535839 intact:EBI-311406|ensembl:ENSP00000479811|uniprotkb:E9PFZ6|uniprotkb:Q86YZ7 psi-mi:bcl7c_human(display_long)|uniprotkb:BCL7C(gene name)|psi-mi:BCL7C(display_short) psi-mi:cntp4_human(display_long)|uniprotkb:CNTNAP4(gene name)|psi-mi:CNTNAP4(display_short)|uniprotkb:CASPR4(gene name synonym)|uniprotkb:KIAA1763(gene name synonym)|uniprotkb:Cell recognition molecule Caspr4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476547|imex:IM-26985-531 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001273455.1|ensembl:ENSP00000215115|ensembl:ENST00000380317|ensembl:ENSP00000369674|ensembl:ENSG00000099385(gene)|ensembl:ENST00000215115(transcript)|go:"GO:0006915"(apoptotic process)|interpro:IPR006804(BCL7, N-terminal)|mint:Q8WUZ0|refseq:NP_004756.2 refseq:NP_207837.2|ensembl:ENSG00000152910(gene)|ensembl:ENST00000611870(transcript)|go:"GO:0007155"(cell adhesion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032225"(regulation of synaptic transmission, dopaminergic)|go:"GO:0032228"(regulation of synaptic transmission, GABAergic)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042995"(cell projection)|go:"GO:2000821"(regulation of grooming behavior)|interpro:IPR000421(Coagulation factor 5/8 type, C-terminal)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001791(Laminin G)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR008979(Galactose-binding like)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR028875|interpro:IPR036056|mint:Q9C0A0|rcsb pdb:4NXQ|refseq:NP_620481.2|dip:DIP-31652N - comment:mint|comment:homomint|function:May play an anti-apoptotic role comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:XuyDhxOhWHNVXmgi/WXLmCvKn409606 rogid:P1oT4UCmiYpfcKPyTC4p4Ao9gbQ9606 rigid:3fK9ES0QT5FEfdhSyeOzdmQEIDU false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUZ0 uniprotkb:P52292 intact:EBI-7850114|intact:EBI-28969068|ensembl:ENSP00000215115|uniprotkb:Q6PD89|uniprotkb:O43770|intact:MINT-4535839 intact:EBI-349938|uniprotkb:Q9BRU5|ensembl:ENSP00000504685|intact:EBI-28977049|ensembl:ENSP00000332455|ensembl:ENSP00000438483|ensembl:ENSP00000462331|ensembl:ENSP00000463602|ensembl:ENSP00000504655|uniprotkb:B9EJD6|uniprotkb:Q53YE3|intact:EBI-9377406|uniprotkb:Q6NVW7 psi-mi:bcl7c_human(display_long)|uniprotkb:BCL7C(gene name)|psi-mi:BCL7C(display_short) psi-mi:ima1_human(display_long)|uniprotkb:KPNA2(gene name)|psi-mi:KPNA2(display_short)|uniprotkb:RCH1(gene name synonym)|uniprotkb:SRP1(gene name synonym)|uniprotkb:Karyopherin subunit alpha-2(gene name synonym)|uniprotkb:SRP1-alpha(gene name synonym)|uniprotkb:RAG cohort protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476547|imex:IM-26985-531 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001273455.1|ensembl:ENSP00000215115|ensembl:ENST00000380317|ensembl:ENSP00000369674|ensembl:ENSG00000099385(gene)|ensembl:ENST00000215115(transcript)|go:"GO:0006915"(apoptotic process)|interpro:IPR006804(BCL7, N-terminal)|mint:Q8WUZ0|refseq:NP_004756.2 refseq:NP_002257.1|refseq:NP_001307540.1|ensembl:ENST00000330459(transcript)|ensembl:ENST00000537025(transcript)|ensembl:ENST00000579754(transcript)|ensembl:ENST00000584026(transcript)|ensembl:ENST00000677086(transcript)|ensembl:ENST00000679078(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043657"(host cell)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0075506"(entry of viral genome into host nucleus through nuclear pore complex via importin)|go:"GO:0098892"(extrinsic component of postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1903902"(positive regulation of viral life cycle)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:P52292|rcsb pdb:1EFX|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:3FEX|ensembl:ENSG00000182481(gene)|rcsb pdb:3FEY|rcsb pdb:3WPT|rcsb pdb:4E4V|rcsb pdb:4WV6|rcsb pdb:5H43|rcsb pdb:7N8J|reactome:R-HSA-111932|reactome:R-HSA-1169408|reactome:R-HSA-168276|reactome:R-HSA-442729|reactome:R-HSA-5693548|reactome:R-HSA-9018519|ensembl:ENSP00000332455|ensembl:ENSP00000438483|ensembl:ENSP00000462331|ensembl:ENSP00000463602|ensembl:ENSP00000504655|ensembl:ENSP00000504685|dip:DIP-6205N - comment:mint|comment:homomint|function:May play an anti-apoptotic role comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:XuyDhxOhWHNVXmgi/WXLmCvKn409606 rogid:DFtAbvPxkzWJO/fRLPGxA6pEEJQ9606 rigid:3fK9ES0QT5FEfdhSyeOzdmQEIDU false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUZ0 uniprotkb:P59998 intact:EBI-7850114|intact:EBI-28969068|ensembl:ENSP00000215115|uniprotkb:Q6PD89|uniprotkb:O43770|intact:MINT-4535839 intact:EBI-351872|uniprotkb:O15509|uniprotkb:C9JWM7|uniprotkb:E7ETI0|uniprotkb:Q6P0W5|uniprotkb:Q96QJ3|ensembl:ENSP00000380431|uniprotkb:F6TTL5 psi-mi:bcl7c_human(display_long)|uniprotkb:BCL7C(gene name)|psi-mi:BCL7C(display_short) psi-mi:arpc4_human(display_long)|uniprotkb:ARPC4(gene name)|psi-mi:ARPC4(display_short)|uniprotkb:ARC20(gene name synonym)|uniprotkb:Arp2/3 complex 20 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476547|imex:IM-26985-531 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001273455.1|ensembl:ENSP00000215115|ensembl:ENST00000380317|ensembl:ENSP00000369674|ensembl:ENSG00000099385(gene)|ensembl:ENST00000215115(transcript)|go:"GO:0006915"(apoptotic process)|interpro:IPR006804(BCL7, N-terminal)|mint:Q8WUZ0|refseq:NP_004756.2 refseq:NP_001185709.1|refseq:NP_005709.1|ensembl:ENSG00000241553(gene)|ensembl:ENST00000397261(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005885"(Arp2/3 protein complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042995"(cell projection)|go:"GO:0045010"(actin nucleation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008384(ARP23 complex 20 kDa subunit)|interpro:IPR034666|mint:P59998|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|reactome:R-HSA-3928662|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|refseq:NP_001020130.1|refseq:NP_001020131.1|dip:DIP-33188N - comment:mint|comment:homomint|function:May play an anti-apoptotic role comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:XuyDhxOhWHNVXmgi/WXLmCvKn409606 rogid:Iqe60TWfO3QBVOY+fOqZd9JWfIE9606 rigid:3fK9ES0QT5FEfdhSyeOzdmQEIDU false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUZ0 uniprotkb:O15144 intact:EBI-7850114|intact:EBI-28969068|ensembl:ENSP00000215115|uniprotkb:Q6PD89|uniprotkb:O43770|intact:MINT-4535839 intact:EBI-352356|uniprotkb:Q92801|uniprotkb:Q9P1D4|ensembl:ENSP00000295685|ensembl:ENSP00000327137 psi-mi:bcl7c_human(display_long)|uniprotkb:BCL7C(gene name)|psi-mi:BCL7C(display_short) psi-mi:arpc2_human(display_long)|uniprotkb:ARPC2(gene name)|psi-mi:ARPC2(display_short)|uniprotkb:ARC34(gene name synonym)|uniprotkb:PRO2446(orf name)|uniprotkb:Arp2/3 complex 34 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476547|imex:IM-26985-531 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001273455.1|ensembl:ENSP00000215115|ensembl:ENST00000380317|ensembl:ENSP00000369674|ensembl:ENSG00000099385(gene)|ensembl:ENST00000215115(transcript)|go:"GO:0006915"(apoptotic process)|interpro:IPR006804(BCL7, N-terminal)|mint:Q8WUZ0|refseq:NP_004756.2 refseq:NP_005722.1|refseq:NP_690601.1|go:"GO:0005925"(focal adhesion)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0034314"(Arp2/3 complex-mediated actin nucleation)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036195"(muscle cell projection membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070358"(actin polymerization-dependent cell motility)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|interpro:IPR007188(Arp2/3 complex, 34kDa subunit p34-Arc)|interpro:IPR034666|mint:O15144|rcsb pdb:6UHC|rcsb pdb:6YW6|rcsb pdb:6YW7|reactome:R-HSA-2029482|go:"GO:0005885"(Arp2/3 protein complex)|reactome:R-HSA-5663213|reactome:R-HSA-8856828|reactome:R-HSA-9664422|reactome:R-HSA-3928662|ensembl:ENSG00000163466(gene)|ensembl:ENST00000295685(transcript)|ensembl:ENST00000315717(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|dip:DIP-33197N - comment:mint|comment:homomint|function:May play an anti-apoptotic role comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:XuyDhxOhWHNVXmgi/WXLmCvKn409606 rogid:v5OozQTt614rvrBBoUavbAzjgZ49606 rigid:3fK9ES0QT5FEfdhSyeOzdmQEIDU false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUZ0 uniprotkb:Q8N1F8 intact:EBI-7850114|intact:EBI-28969068|ensembl:ENSP00000215115|uniprotkb:Q6PD89|uniprotkb:O43770|intact:MINT-4535839 intact:EBI-2340204|uniprotkb:Q8NAW9|uniprotkb:Q96PY9|uniprotkb:Q8WXE4|uniprotkb:Q96CN3|uniprotkb:C9JQV3|ensembl:ENSP00000389383 psi-mi:bcl7c_human(display_long)|uniprotkb:BCL7C(gene name)|psi-mi:BCL7C(display_short) psi-mi:s11ip_human(display_long)|uniprotkb:STK11IP(gene name)|psi-mi:STK11IP(display_short)|uniprotkb:KIAA1898(gene name synonym)|uniprotkb:LIP1(gene name synonym)|uniprotkb:LKB1IP(gene name synonym)|uniprotkb:STK11IP1(gene name synonym)|uniprotkb:LKB1-interacting protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476547|imex:IM-26985-531 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001273455.1|ensembl:ENSP00000215115|ensembl:ENST00000380317|ensembl:ENSP00000369674|ensembl:ENSG00000099385(gene)|ensembl:ENST00000215115(transcript)|go:"GO:0006915"(apoptotic process)|interpro:IPR006804(BCL7, N-terminal)|mint:Q8WUZ0|refseq:NP_004756.2 refseq:NP_443134.3|ensembl:ENSG00000144589(gene)|ensembl:ENST00000456909(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0008104"(protein localization)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035578"(azurophil granule lumen)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR031782|interpro:IPR032675|mint:Q8N1F8|reactome:R-HSA-6798695 - comment:mint|comment:homomint|function:May play an anti-apoptotic role comment:"author score: 34" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:XuyDhxOhWHNVXmgi/WXLmCvKn409606 rogid:bkZvSPFpB2rsgtmUrzt1YPiGrp49606 rigid:3fK9ES0QT5FEfdhSyeOzdmQEIDU false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUZ0 uniprotkb:P68032 intact:EBI-7850114|intact:EBI-28969068|ensembl:ENSP00000215115|uniprotkb:Q6PD89|uniprotkb:O43770|intact:MINT-4535839 intact:EBI-352273|uniprotkb:P04270|ensembl:ENSP00000290378 psi-mi:bcl7c_human(display_long)|uniprotkb:BCL7C(gene name)|psi-mi:BCL7C(display_short) psi-mi:actc_human(display_long)|uniprotkb:ACTC1(gene name)|psi-mi:ACTC1(display_short)|uniprotkb:ACTC(gene name synonym)|uniprotkb:Alpha-cardiac actin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476547|imex:IM-26985-531 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001273455.1|ensembl:ENSP00000215115|ensembl:ENST00000380317|ensembl:ENSP00000369674|ensembl:ENSG00000099385(gene)|ensembl:ENST00000215115(transcript)|go:"GO:0006915"(apoptotic process)|interpro:IPR006804(BCL7, N-terminal)|mint:Q8WUZ0|refseq:NP_004756.2 refseq:NP_005150.1|ensembl:ENSG00000159251(gene)|ensembl:ENST00000290378(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031674"(I band)|go:"GO:0033275"(actin-myosin filament sliding)|go:"GO:0042493"|go:"GO:0044297"(cell body)|go:"GO:0045471"(response to ethanol)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0060047"(heart contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68032|reactome:R-HSA-390522|reactome:R-HSA-8980692|reactome:R-HSA-9013026 - comment:mint|comment:homomint|function:May play an anti-apoptotic role comment:"author score: 35" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:XuyDhxOhWHNVXmgi/WXLmCvKn409606 rogid:U/lKYqWUWMSC3fBHFaAcgzfk+3w9606 rigid:3fK9ES0QT5FEfdhSyeOzdmQEIDU false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUZ0 uniprotkb:Q8WUB8 intact:EBI-7850114|intact:EBI-28969068|ensembl:ENSP00000215115|uniprotkb:Q6PD89|uniprotkb:O43770|intact:MINT-4535839 intact:EBI-716462|uniprotkb:Q2YDA3|uniprotkb:Q9BXD2|uniprotkb:Q53HG8|uniprotkb:Q9NV26|ensembl:ENSP00000341805 psi-mi:bcl7c_human(display_long)|uniprotkb:BCL7C(gene name)|psi-mi:BCL7C(display_short) psi-mi:phf10_human(display_long)|uniprotkb:XAP135(gene name synonym)|uniprotkb:PHF10(gene name)|psi-mi:PHF10(display_short)|uniprotkb:BAF45A(gene name synonym)|uniprotkb:BRG1-associated factor 45a(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476547|imex:IM-26985-531 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001273455.1|ensembl:ENSP00000215115|ensembl:ENST00000380317|ensembl:ENSP00000369674|ensembl:ENSG00000099385(gene)|ensembl:ENST00000215115(transcript)|go:"GO:0006915"(apoptotic process)|interpro:IPR006804(BCL7, N-terminal)|mint:Q8WUZ0|refseq:NP_004756.2 refseq:NP_060758.2|refseq:NP_579866.2|ensembl:ENSG00000130024(gene)|ensembl:ENST00000339209(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071564"(npBAF complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR038045|mint:Q8WUB8 - comment:mint|comment:homomint|function:May play an anti-apoptotic role comment:"author score: 40" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:XuyDhxOhWHNVXmgi/WXLmCvKn409606 rogid:QppOFkomM0Lm/7EjW4Fov8NhB049606 rigid:3fK9ES0QT5FEfdhSyeOzdmQEIDU false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUZ0 uniprotkb:Q9NZM4 intact:EBI-7850114|intact:EBI-28969068|ensembl:ENSP00000215115|uniprotkb:Q6PD89|uniprotkb:O43770|intact:MINT-4535839 intact:EBI-1754943|uniprotkb:A8MW01|intact:EBI-28975771|ensembl:ENSP00000379946 psi-mi:bcl7c_human(display_long)|uniprotkb:BCL7C(gene name)|psi-mi:BCL7C(display_short) psi-mi:bicra_human(display_long)|uniprotkb:BICRA(gene name)|psi-mi:BICRA(display_short)|uniprotkb:GLTSCR1(gene name synonym)|uniprotkb:Glioma tumor suppressor candidate region gene 1 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476547|imex:IM-26985-531 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001273455.1|ensembl:ENSP00000215115|ensembl:ENST00000380317|ensembl:ENSP00000369674|ensembl:ENSG00000099385(gene)|ensembl:ENST00000215115(transcript)|go:"GO:0006915"(apoptotic process)|interpro:IPR006804(BCL7, N-terminal)|mint:Q8WUZ0|refseq:NP_004756.2 ensembl:ENSP00000379946|ensembl:ENST00000614245|ensembl:ENSP00000480219|refseq:NP_056526.3|refseq:XP_005258890.1|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0140537"(transcription regulator activator activity)|interpro:IPR015671(Glioma tumour suppressor candidate region gene 1)|interpro:IPR038842|mint:Q9NZM4|ensembl:ENSG00000063169(gene)|ensembl:ENST00000396720(transcript)|go:"GO:0005634"(nucleus) - comment:mint|comment:homomint|function:May play an anti-apoptotic role comment:"author score: 47" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:XuyDhxOhWHNVXmgi/WXLmCvKn409606 rogid:iJokFxqZtCvuWinjN0DR51nuMQU9606 rigid:3fK9ES0QT5FEfdhSyeOzdmQEIDU false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUZ0 uniprotkb:Q9H8M2 intact:EBI-7850114|intact:EBI-28969068|ensembl:ENSP00000215115|uniprotkb:Q6PD89|uniprotkb:O43770|intact:MINT-4535839 intact:EBI-10258305|uniprotkb:B4DMQ2|uniprotkb:Q9H7R9|uniprotkb:Q6UWU9|uniprotkb:A6NFY8|uniprotkb:B4DR93|uniprotkb:Q2XUS1|uniprotkb:Q8IUS4|uniprotkb:Q9H5Q5|ensembl:ENSP00000419765 psi-mi:bcl7c_human(display_long)|uniprotkb:BCL7C(gene name)|psi-mi:BCL7C(display_short) psi-mi:brd9_human(display_long)|uniprotkb:BRD9(gene name)|psi-mi:BRD9(display_short)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.8(gene name synonym)|uniprotkb:UNQ3040/PRO9856(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476547|imex:IM-26985-531 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001273455.1|ensembl:ENSP00000215115|ensembl:ENST00000380317|ensembl:ENSP00000369674|ensembl:ENSG00000099385(gene)|ensembl:ENST00000215115(transcript)|go:"GO:0006915"(apoptotic process)|interpro:IPR006804(BCL7, N-terminal)|mint:Q8WUZ0|refseq:NP_004756.2 refseq:NP_001304880.1|refseq:NP_001009877.2|refseq:NP_076413.3|ensembl:ENSG00000028310(gene)|ensembl:ENST00000467963(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0070577"(lysine-acetylated histone binding)|interpro:IPR001487(Bromodomain)|interpro:IPR021900|interpro:IPR036427|mint:Q9H8M2|rcsb pdb:3HME|rcsb pdb:4NQN|rcsb pdb:4UIT|rcsb pdb:4UIU|rcsb pdb:4UIV|rcsb pdb:4UIW|rcsb pdb:4XY8|rcsb pdb:4YY4|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4Z6H|rcsb pdb:4Z6I|rcsb pdb:5E9V|rcsb pdb:5EU1|rcsb pdb:5F1H|rcsb pdb:5F1L|rcsb pdb:5F25|rcsb pdb:5F2P|rcsb pdb:5I40|rcsb pdb:5I7X|rcsb pdb:5I7Y|rcsb pdb:5IGM|rcsb pdb:5IGN|rcsb pdb:5JI8|rcsb pdb:5MKY|rcsb pdb:5TWX|rcsb pdb:6BQA|rcsb pdb:6HM0|rcsb pdb:6UZF|rcsb pdb:6V0S|rcsb pdb:6V0X|rcsb pdb:6V14|rcsb pdb:6V1B|rcsb pdb:6Y7H|rcsb pdb:6Y7I|rcsb pdb:6Y7J|rcsb pdb:6Y7K|rcsb pdb:6Y7L|rcsb pdb:6YQR|rcsb pdb:6YQS|rcsb pdb:6YQW - comment:mint|comment:homomint|function:May play an anti-apoptotic role comment:"author score: 57" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:XuyDhxOhWHNVXmgi/WXLmCvKn409606 rogid:5b4IZUgA/WG/HR0Rf9y1nYqs3Ho9606 rigid:3fK9ES0QT5FEfdhSyeOzdmQEIDU false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUZ0 uniprotkb:Q92784 intact:EBI-7850114|intact:EBI-28969068|ensembl:ENSP00000215115|uniprotkb:Q6PD89|uniprotkb:O43770|intact:MINT-4535839 intact:EBI-16355309|ensembl:ENSP00000450518|uniprotkb:A8MSI3|uniprotkb:B7Z276|uniprotkb:F5H575|uniprotkb:Q32UJ0|uniprotkb:Q6P9E6|uniprotkb:Q6ZT41|uniprotkb:Q9H7Y5 psi-mi:bcl7c_human(display_long)|uniprotkb:BCL7C(gene name)|psi-mi:BCL7C(display_short) psi-mi:dpf3_human(display_long)|uniprotkb:DPF3(gene name)|psi-mi:DPF3(display_short)|uniprotkb:BAF45C(gene name synonym)|uniprotkb:BRG1-associated factor 45C(gene name synonym)|uniprotkb:CERD4(gene name synonym)|uniprotkb:Zinc finger protein cer-d4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476547|imex:IM-26985-531 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001273455.1|ensembl:ENSP00000215115|ensembl:ENST00000380317|ensembl:ENSP00000369674|ensembl:ENSG00000099385(gene)|ensembl:ENST00000215115(transcript)|go:"GO:0006915"(apoptotic process)|interpro:IPR006804(BCL7, N-terminal)|mint:Q8WUZ0|refseq:NP_004756.2 ensembl:ENSG00000205683(gene)|ensembl:ENST00000556509(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071565"(nBAF complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR019787|interpro:IPR025750|interpro:IPR036236|interpro:IPR038047|mint:Q92784|rcsb pdb:2KWJ|rcsb pdb:2KWK|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:5I3L|rcsb pdb:5SZB|rcsb pdb:5SZC|go:"GO:0007399"(nervous system development)|dip:DIP-59245N|refseq:NP_001267471.1|refseq:NP_001267472.1|refseq:NP_001267473.1|refseq:NP_036206.3|refseq:XP_016877159.1|refseq:XP_016877160.1 - comment:mint|comment:homomint|function:May play an anti-apoptotic role comment:"author score: 67" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:XuyDhxOhWHNVXmgi/WXLmCvKn409606 rogid:O97+tk0b//PukSNQS/JTPszyqbU9606 rigid:3fK9ES0QT5FEfdhSyeOzdmQEIDU false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUZ0 uniprotkb:Q92782 intact:EBI-7850114|intact:EBI-28969068|ensembl:ENSP00000215115|uniprotkb:Q6PD89|uniprotkb:O43770|intact:MINT-4535839 intact:EBI-726953|uniprotkb:B3KSY8|uniprotkb:Q08AJ0 psi-mi:bcl7c_human(display_long)|uniprotkb:BCL7C(gene name)|psi-mi:BCL7C(display_short) psi-mi:dpf1_human(display_long)|uniprotkb:D4, zinc and double PHD fingers family 1(gene name synonym)|uniprotkb:DPF1(gene name)|psi-mi:DPF1(display_short)|uniprotkb:NEUD4(gene name synonym)|uniprotkb:BAF45B(gene name synonym)|uniprotkb:BRG1-associated factor 45B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476547|imex:IM-26985-531 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001273455.1|ensembl:ENSP00000215115|ensembl:ENST00000380317|ensembl:ENSP00000369674|ensembl:ENSG00000099385(gene)|ensembl:ENST00000215115(transcript)|go:"GO:0006915"(apoptotic process)|interpro:IPR006804(BCL7, N-terminal)|mint:Q8WUZ0|refseq:NP_004756.2 refseq:NP_001128627.1|refseq:NP_001128628.1|refseq:NP_004638.2|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR019787|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071565"(nBAF complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|mint:Q92782|interpro:IPR025750|refseq:NP_001276907.1|interpro:IPR038046 - comment:mint|comment:homomint|function:May play an anti-apoptotic role comment:"author score: 70" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:XuyDhxOhWHNVXmgi/WXLmCvKn409606 rogid:WnpwDXkyVSACQWBHcW9Rcj12O/o9606 rigid:3fK9ES0QT5FEfdhSyeOzdmQEIDU false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUZ0 uniprotkb:Q4VC05 intact:EBI-7850114|intact:EBI-28969068|ensembl:ENSP00000215115|uniprotkb:Q6PD89|uniprotkb:O43770|intact:MINT-4535839 intact:EBI-359917|uniprotkb:Q13843|uniprotkb:B4DJN6|uniprotkb:B7ZB21|uniprotkb:Q14CT7|intact:EBI-2560561|ensembl:ENSP00000261822|ensembl:ENSP00000489305 psi-mi:bcl7c_human(display_long)|uniprotkb:BCL7C(gene name)|psi-mi:BCL7C(display_short) psi-mi:bcl7a_human(display_long)|uniprotkb:BCL7A(gene name)|psi-mi:BCL7A(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476547|imex:IM-26985-531 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001273455.1|ensembl:ENSP00000215115|ensembl:ENST00000380317|ensembl:ENSP00000369674|ensembl:ENSG00000099385(gene)|ensembl:ENST00000215115(transcript)|go:"GO:0006915"(apoptotic process)|interpro:IPR006804(BCL7, N-terminal)|mint:Q8WUZ0|refseq:NP_004756.2 refseq:NP_001019979.1|refseq:NP_066273.1|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR006804(BCL7, N-terminal)|mint:Q4VC05|ensembl:ENSG00000110987(gene)|ensembl:ENSG00000282873(gene)|ensembl:ENST00000261822(transcript)|ensembl:ENST00000635403(transcript)|dip:DIP-27608N - comment:mint|comment:homomint|function:May play an anti-apoptotic role comment:"author score: 82" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:XuyDhxOhWHNVXmgi/WXLmCvKn409606 rogid:ZEtiQWH57T+t+gCMVVPHAJUO10w9606 rigid:3fK9ES0QT5FEfdhSyeOzdmQEIDU false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUZ0 uniprotkb:O75177 intact:EBI-7850114|intact:EBI-28969068|ensembl:ENSP00000215115|uniprotkb:Q6PD89|uniprotkb:O43770|intact:MINT-4535839 intact:EBI-744674|uniprotkb:Q5JXJ3|uniprotkb:Q8NE69|uniprotkb:Q9BR55|uniprotkb:Q9H4K6|uniprotkb:A6NNE3|uniprotkb:A8K620|uniprotkb:B3KWR8|uniprotkb:Q6MZV9|uniprotkb:Q6NTH3|uniprotkb:Q6XYD9|uniprotkb:E1P5H7|ensembl:ENSP00000333012 psi-mi:bcl7c_human(display_long)|uniprotkb:BCL7C(gene name)|psi-mi:BCL7C(display_short) psi-mi:crest_human(display_long)|uniprotkb:SYT homolog 1(gene name synonym)|uniprotkb:KIAA0693(gene name synonym)|uniprotkb:SS18L1(gene name)|psi-mi:SS18L1(display_short)|uniprotkb:CREST(gene name synonym)|uniprotkb:SS18-like protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476547|imex:IM-26985-531 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001273455.1|ensembl:ENSP00000215115|ensembl:ENST00000380317|ensembl:ENSP00000369674|ensembl:ENSG00000099385(gene)|ensembl:ENST00000215115(transcript)|go:"GO:0006915"(apoptotic process)|interpro:IPR006804(BCL7, N-terminal)|mint:Q8WUZ0|refseq:NP_004756.2 refseq:NP_945173.1|refseq:XP_011527066.1|refseq:XP_011527069.1|ensembl:ENSG00000184402(gene)|ensembl:ENST00000331758(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0016358"(dendrite development)|go:"GO:0016604"(nuclear body)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0071565"(nBAF complex)|interpro:IPR007726(SSXT)|interpro:IPR044779|mint:O75177|refseq:NP_001288707.1|refseq:XP_005260448.1 - comment:mint|comment:homomint|function:May play an anti-apoptotic role comment:"author score: 86" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:XuyDhxOhWHNVXmgi/WXLmCvKn409606 rogid:A7XGgvW0Roha0A4GgF5VvOC7dYs9606 rigid:3fK9ES0QT5FEfdhSyeOzdmQEIDU false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUZ0 uniprotkb:Q15532 intact:EBI-7850114|intact:EBI-28969068|ensembl:ENSP00000215115|uniprotkb:Q6PD89|uniprotkb:O43770|intact:MINT-4535839 intact:EBI-2560599|uniprotkb:Q4VAX1|uniprotkb:Q16404|uniprotkb:B0YJ95|uniprotkb:Q9BXC6|ensembl:ENSP00000414516 psi-mi:bcl7c_human(display_long)|uniprotkb:BCL7C(gene name)|psi-mi:BCL7C(display_short) psi-mi:ssxt_human(display_long)|uniprotkb:SS18(gene name)|psi-mi:SS18(display_short)|uniprotkb:SSXT(gene name synonym)|uniprotkb:SYT(gene name synonym)|uniprotkb:Synovial sarcoma translocated to X chromosome protein(gene name synonym)|uniprotkb:Protein SYT(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476547|imex:IM-26985-531 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001273455.1|ensembl:ENSP00000215115|ensembl:ENST00000380317|ensembl:ENSP00000369674|ensembl:ENSG00000099385(gene)|ensembl:ENST00000215115(transcript)|go:"GO:0006915"(apoptotic process)|interpro:IPR006804(BCL7, N-terminal)|mint:Q8WUZ0|refseq:NP_004756.2 refseq:NP_001007560.1|refseq:NP_001295130.1|refseq:NP_005628.2|ensembl:ENSG00000141380(gene)|ensembl:ENST00000415083(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0071564"(npBAF complex)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR007726(SSXT)|interpro:IPR044779|mint:Q15532|ensembl:ENST00000269137|ensembl:ENSP00000269137|ensembl:ENSP00000414516 - comment:mint|comment:homomint|function:May play an anti-apoptotic role comment:"author score: 86" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:XuyDhxOhWHNVXmgi/WXLmCvKn409606 rogid:qECbpt+KgdXXqUWQnrsL7rwxznQ9606 rigid:3fK9ES0QT5FEfdhSyeOzdmQEIDU false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUZ0 uniprotkb:Q9NPI1 intact:EBI-7850114|intact:EBI-28969068|ensembl:ENSP00000215115|uniprotkb:Q6PD89|uniprotkb:O43770|intact:MINT-4535839 intact:EBI-711221|uniprotkb:Q4VC09|uniprotkb:Q8N2L9|uniprotkb:Q96KA4|uniprotkb:Q9BV48|uniprotkb:Q9UH59|intact:EBI-2560548|ensembl:ENSP00000378180 psi-mi:bcl7c_human(display_long)|uniprotkb:BCL7C(gene name)|psi-mi:BCL7C(display_short) psi-mi:brd7_human(display_long)|uniprotkb:75 kDa bromodomain protein(gene name synonym)|uniprotkb:Protein CELTIX-1(gene name synonym)|uniprotkb:BRD7(gene name)|psi-mi:BRD7(display_short)|uniprotkb:BP75(gene name synonym)|uniprotkb:CELTIX1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476547|imex:IM-26985-531 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001273455.1|ensembl:ENSP00000215115|ensembl:ENST00000380317|ensembl:ENSP00000369674|ensembl:ENSG00000099385(gene)|ensembl:ENST00000215115(transcript)|go:"GO:0006915"(apoptotic process)|interpro:IPR006804(BCL7, N-terminal)|mint:Q8WUZ0|refseq:NP_004756.2 refseq:NP_001167455.1|refseq:NP_037395.2|dip:DIP-32509N|ensembl:ENSG00000166164(gene)|ensembl:ENST00000394688(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001487(Bromodomain)|interpro:IPR021900|interpro:IPR036427|mint:Q9NPI1|rcsb pdb:2I7K|rcsb pdb:5MQ1|rcsb pdb:6PPA|rcsb pdb:6V0Q|rcsb pdb:6V16|rcsb pdb:6V17|rcsb pdb:6V1E|rcsb pdb:6V1F|rcsb pdb:6V1H|reactome:R-HSA-6804758 - comment:mint|comment:homomint|function:May play an anti-apoptotic role comment:"author score: 92" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:XuyDhxOhWHNVXmgi/WXLmCvKn409606 rogid:F1N3XsdbpPy8TgHdMLSmnhdKNYs9606 rigid:3fK9ES0QT5FEfdhSyeOzdmQEIDU false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUZ0 uniprotkb:Q8TAQ2 intact:EBI-7850114|intact:EBI-28969068|ensembl:ENSP00000215115|uniprotkb:Q6PD89|uniprotkb:O43770|intact:MINT-4535839 intact:EBI-357418|ensembl:ENSP00000267064|uniprotkb:Q92923|uniprotkb:Q96E12|uniprotkb:Q96GY4|intact:EBI-1759986|intact:EBI-1965079|uniprotkb:F8VTJ5|uniprotkb:Q59GV3 psi-mi:bcl7c_human(display_long)|uniprotkb:BCL7C(gene name)|psi-mi:BCL7C(display_short) psi-mi:smrc2_human(display_long)|uniprotkb:SMARCC2(gene name)|psi-mi:SMARCC2(display_short)|uniprotkb:BAF170(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2(gene name synonym)|uniprotkb:SWI/SNF complex 170 kDa subunit(gene name synonym)|uniprotkb:BRG1-associated factor 170(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476547|imex:IM-26985-531 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001273455.1|ensembl:ENSP00000215115|ensembl:ENST00000380317|ensembl:ENSP00000369674|ensembl:ENSG00000099385(gene)|ensembl:ENST00000215115(transcript)|go:"GO:0006915"(apoptotic process)|interpro:IPR006804(BCL7, N-terminal)|mint:Q8WUZ0|refseq:NP_004756.2 ensembl:ENSG00000139613(gene)|ensembl:ENST00000267064(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR000953(Chromo domain)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR032448|interpro:IPR032450|interpro:IPR032451|interpro:IPR036388|interpro:IPR036420|interpro:IPR038044|mint:Q8TAQ2|rcsb pdb:6KAG|rcsb pdb:6LTH|rcsb pdb:6LTJ|reactome:R-HSA-3214858|reactome:R-HSA-8939243|refseq:NP_003066.2|refseq:NP_001123892.1|refseq:NP_620706.1|refseq:NP_001317217.1|dip:DIP-27611N - comment:mint|comment:homomint|function:May play an anti-apoptotic role comment:"author score: 146" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:XuyDhxOhWHNVXmgi/WXLmCvKn409606 rogid:60gIB3J1YI/FzqVCzdoSg1Oj3ME9606 rigid:3fK9ES0QT5FEfdhSyeOzdmQEIDU false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUZ0 uniprotkb:P51532 intact:EBI-7850114|intact:EBI-28969068|ensembl:ENSP00000215115|uniprotkb:Q6PD89|uniprotkb:O43770|intact:MINT-4535839 intact:EBI-302489|uniprotkb:O95052|uniprotkb:Q9HBD3|uniprotkb:B1A8Z4|uniprotkb:B1A8Z5|uniprotkb:B1A8Z6|uniprotkb:B1A8Z7|uniprotkb:E9PBR8|ensembl:ENSP00000343896|ensembl:ENSP00000395654 psi-mi:bcl7c_human(display_long)|uniprotkb:BCL7C(gene name)|psi-mi:BCL7C(display_short) psi-mi:smca4_human(display_long)|uniprotkb:SMARCA4(gene name)|psi-mi:SMARCA4(display_short)|uniprotkb:BRG1(gene name synonym)|uniprotkb:SNF2B(gene name synonym)|uniprotkb:SNF2L4(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA4(gene name synonym)|uniprotkb:SNF2-beta(gene name synonym)|uniprotkb:BAF190A(gene name synonym)|uniprotkb:Mitotic growth and transcription activator(gene name synonym)|uniprotkb:Protein BRG-1(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4(gene name synonym)|uniprotkb:Protein brahma homolog 1(gene name synonym)|uniprotkb:BRG1-associated factor 190A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476547|imex:IM-26985-531 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001273455.1|ensembl:ENSP00000215115|ensembl:ENST00000380317|ensembl:ENSP00000369674|ensembl:ENSG00000099385(gene)|ensembl:ENST00000215115(transcript)|go:"GO:0006915"(apoptotic process)|interpro:IPR006804(BCL7, N-terminal)|mint:Q8WUZ0|refseq:NP_004756.2 refseq:NP_001122316.1|refseq:NP_003063.2|refseq:NP_001122317.1|refseq:NP_001122318.1|refseq:NP_001122319.1|refseq:NP_001122320.1|dip:DIP-24249N|refseq:XP_016882654.1|refseq:XP_016882655.1|refseq:XP_016882656.1|refseq:XP_016882657.1|ensembl:ENSG00000127616(gene)|ensembl:ENST00000344626(transcript)|ensembl:ENST00000429416(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0002039"(p53 binding)|go:"GO:0003407"(neural retina development)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030100|interpro:IPR036427|interpro:IPR037259|interpro:IPR038718|mint:P51532|rcsb pdb:2GRC|rcsb pdb:2H60|rcsb pdb:3UVD|rcsb pdb:5DKD|rcsb pdb:5EA1|rcsb pdb:6BGH|rcsb pdb:6HR2|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6SY2|rcsb pdb:6ZS2|reactome:R-HSA-1266695|reactome:R-HSA-201722|reactome:R-HSA-3214858|reactome:R-HSA-3247509|reactome:R-HSA-8939243|reactome:R-HSA-9619665 - comment:mint|comment:homomint|function:May play an anti-apoptotic role comment:"author score: 152" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:XuyDhxOhWHNVXmgi/WXLmCvKn409606 rogid:Ztr+2IXfAxueSUaNYG2A47HoMes9606 rigid:3fK9ES0QT5FEfdhSyeOzdmQEIDU false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUZ0 uniprotkb:Q6STE5 intact:EBI-7850114|intact:EBI-28969068|ensembl:ENSP00000215115|uniprotkb:Q6PD89|uniprotkb:O43770|intact:MINT-4535839 intact:EBI-465496|ensembl:ENSP00000262188|uniprotkb:Q75MJ2|uniprotkb:Q75MR8|uniprotkb:Q92926|uniprotkb:Q9BUH1|intact:EBI-488496|intact:EBI-1760029|uniprotkb:Q2YD86|uniprotkb:D3DX10 psi-mi:bcl7c_human(display_long)|uniprotkb:BCL7C(gene name)|psi-mi:BCL7C(display_short) psi-mi:smrd3_human(display_long)|uniprotkb:SMARCD3(gene name)|psi-mi:SMARCD3(display_short)|uniprotkb:BAF60C(gene name synonym)|uniprotkb:60 kDa BRG-1/Brm-associated factor subunit C(gene name synonym)|uniprotkb:BRG1-associated factor 60C(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476547|imex:IM-26985-531 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001273455.1|ensembl:ENSP00000215115|ensembl:ENST00000380317|ensembl:ENSP00000369674|ensembl:ENSG00000099385(gene)|ensembl:ENST00000215115(transcript)|go:"GO:0006915"(apoptotic process)|interpro:IPR006804(BCL7, N-terminal)|mint:Q8WUZ0|refseq:NP_004756.2 ensembl:ENSG00000082014(gene)|ensembl:ENST00000262188(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003219"(cardiac right ventricle formation)|go:"GO:0003407"(neural retina development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR003121(SWIB/MDM2)|interpro:IPR019835|interpro:IPR036885|interpro:IPR038043|mint:Q6STE5|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|go:"GO:0016922"(nuclear receptor binding)|reactome:R-HSA-2426168|reactome:R-HSA-3214858|reactome:R-HSA-381340|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-8939243|reactome:R-HSA-9707564|reactome:R-HSA-9707616|reactome:R-HSA-2151201|refseq:NP_001003801.1|refseq:NP_001003802.1|refseq:NP_003069.2|dip:DIP-33012N - comment:mint|comment:homomint|function:May play an anti-apoptotic role comment:"author score: 156" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:XuyDhxOhWHNVXmgi/WXLmCvKn409606 rogid:fCKGyz4ZneKj5VHia17wdMq6neI9606 rigid:3fK9ES0QT5FEfdhSyeOzdmQEIDU false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUZ0 uniprotkb:O96019 intact:EBI-7850114|intact:EBI-28969068|ensembl:ENSP00000215115|uniprotkb:Q6PD89|uniprotkb:O43770|intact:MINT-4535839 intact:EBI-355018|uniprotkb:Q8TAE5|uniprotkb:Q9BVS8|uniprotkb:Q9H0W6|uniprotkb:B3KMN1|uniprotkb:D3DNR9|ensembl:ENSP00000397552 psi-mi:bcl7c_human(display_long)|uniprotkb:BCL7C(gene name)|psi-mi:BCL7C(display_short) psi-mi:acl6a_human(display_long)|uniprotkb:53 kDa BRG1-associated factor A(gene name synonym)|uniprotkb:Actin-related protein Baf53a(gene name synonym)|uniprotkb:ArpNbeta(gene name synonym)|uniprotkb:BAF53A(gene name synonym)|uniprotkb:ACTL6A(gene name)|psi-mi:ACTL6A(display_short)|uniprotkb:BAF53(gene name synonym)|uniprotkb:INO80K(gene name synonym)|uniprotkb:INO80 complex subunit K(gene name synonym)|uniprotkb:BRG1-associated factor 53A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476547|imex:IM-26985-531 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001273455.1|ensembl:ENSP00000215115|ensembl:ENST00000380317|ensembl:ENSP00000369674|ensembl:ENSG00000099385(gene)|ensembl:ENST00000215115(transcript)|go:"GO:0006915"(apoptotic process)|interpro:IPR006804(BCL7, N-terminal)|mint:Q8WUZ0|refseq:NP_004756.2 refseq:NP_004292.1|refseq:NP_817126.1|refseq:NP_829888.1|ensembl:ENSG00000136518(gene)|ensembl:ENST00000429709(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0003407"(neural retina development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0021510"(spinal cord development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043044"|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0071564"(npBAF complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR043129|mint:O96019|rcsb pdb:6LTJ|reactome:R-HSA-3214847|reactome:R-HSA-3214858|go:"GO:0000785"(chromatin)|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8939243|ensembl:ENST00000392662|ensembl:ENSP00000376430|ensembl:ENSP00000397552|ensembl:ENST00000450518|ensembl:ENSP00000394014|dip:DIP-27565N - comment:mint|comment:homomint|function:May play an anti-apoptotic role comment:"author score: 158" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:XuyDhxOhWHNVXmgi/WXLmCvKn409606 rogid:FV8zvQxf2aeHbwFNUpo9JOpj5U49606 rigid:3fK9ES0QT5FEfdhSyeOzdmQEIDU false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUZ0 uniprotkb:Q92922 intact:EBI-7850114|intact:EBI-28969068|ensembl:ENSP00000215115|uniprotkb:Q6PD89|uniprotkb:O43770|intact:MINT-4535839 intact:EBI-355653|uniprotkb:Q6P172|uniprotkb:Q8IWH2|uniprotkb:Q17RS0|ensembl:ENSP00000254480 psi-mi:bcl7c_human(display_long)|uniprotkb:BCL7C(gene name)|psi-mi:BCL7C(display_short) psi-mi:smrc1_human(display_long)|uniprotkb:SMARCC1(gene name)|psi-mi:SMARCC1(display_short)|uniprotkb:BAF155(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1(gene name synonym)|uniprotkb:SWI/SNF complex 155 kDa subunit(gene name synonym)|uniprotkb:BRG1-associated factor 155(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476547|imex:IM-26985-531 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001273455.1|ensembl:ENSP00000215115|ensembl:ENST00000380317|ensembl:ENSP00000369674|ensembl:ENSG00000099385(gene)|ensembl:ENST00000215115(transcript)|go:"GO:0006915"(apoptotic process)|interpro:IPR006804(BCL7, N-terminal)|mint:Q8WUZ0|refseq:NP_004756.2 refseq:NP_003065.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR000953(Chromo domain)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR030087|interpro:IPR032448|interpro:IPR032450|interpro:IPR032451|interpro:IPR036388|interpro:IPR036420|mint:Q92922|rcsb pdb:2YUS|rcsb pdb:5GJK|rcsb pdb:6KZ7|rcsb pdb:6YXO|rcsb pdb:6YXP|reactome:R-HSA-3214858|reactome:R-HSA-8939243|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|ensembl:ENSG00000173473(gene)|ensembl:ENST00000254480(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001741"(XY body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030850"(prostate gland development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|ensembl:ENSP00000254480|dip:DIP-27545N|dip:DIP-33044N - comment:mint|comment:homomint|function:May play an anti-apoptotic role comment:"author score: 160" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:XuyDhxOhWHNVXmgi/WXLmCvKn409606 rogid:Uv0bjPkUICLtOXJcETUXDTLIQhY9606 rigid:3fK9ES0QT5FEfdhSyeOzdmQEIDU false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUZ0 uniprotkb:Q92925 intact:EBI-7850114|intact:EBI-28969068|ensembl:ENSP00000215115|uniprotkb:Q6PD89|uniprotkb:O43770|intact:MINT-4535839 intact:EBI-358441|uniprotkb:Q7L2I6|uniprotkb:Q9UHZ1|uniprotkb:A5PLL5|uniprotkb:A6NNQ7|uniprotkb:B4DV56|uniprotkb:B4E1R6|ensembl:ENSP00000392617 psi-mi:bcl7c_human(display_long)|uniprotkb:BCL7C(gene name)|psi-mi:BCL7C(display_short) psi-mi:smrd2_human(display_long)|uniprotkb:PRO2451(orf name)|uniprotkb:SMARCD2(gene name)|psi-mi:SMARCD2(display_short)|uniprotkb:BAF60B(gene name synonym)|uniprotkb:60 kDa BRG-1/Brm-associated factor subunit B(gene name synonym)|uniprotkb:BRG1-associated factor 60B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476547|imex:IM-26985-531 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001273455.1|ensembl:ENSP00000215115|ensembl:ENST00000380317|ensembl:ENSP00000369674|ensembl:ENSG00000099385(gene)|ensembl:ENST00000215115(transcript)|go:"GO:0006915"(apoptotic process)|interpro:IPR006804(BCL7, N-terminal)|mint:Q8WUZ0|refseq:NP_004756.2 refseq:NP_001091896.1|dip:DIP-31182N|refseq:NP_001317369.1|ensembl:ENSG00000108604(gene)|ensembl:ENST00000448276(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR003121(SWIB/MDM2)|interpro:IPR019835|interpro:IPR030090|interpro:IPR036885|mint:Q92925|reactome:R-HSA-3214858|reactome:R-HSA-8939243 - comment:mint|comment:homomint|function:May play an anti-apoptotic role comment:"author score: 175" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:XuyDhxOhWHNVXmgi/WXLmCvKn409606 rogid:n6YHBJ+cqEmVcXwMYsTZGOfL86A9606 rigid:3fK9ES0QT5FEfdhSyeOzdmQEIDU false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUZ0 uniprotkb:Q96GM5 intact:EBI-7850114|intact:EBI-28969068|ensembl:ENSP00000215115|uniprotkb:Q6PD89|uniprotkb:O43770|intact:MINT-4535839 intact:EBI-358489|intact:EBI-1760001|ensembl:ENSP00000378414|uniprotkb:Q92924|uniprotkb:Q9Y635|intact:EBI-1965109|uniprotkb:A6NN27|intact:EBI-28976725 psi-mi:bcl7c_human(display_long)|uniprotkb:BCL7C(gene name)|psi-mi:BCL7C(display_short) psi-mi:smrd1_human(display_long)|uniprotkb:SMARCD1(gene name)|psi-mi:SMARCD1(display_short)|uniprotkb:BAF60A(gene name synonym)|uniprotkb:SWI/SNF complex 60 kDa subunit(gene name synonym)|uniprotkb:60 kDa BRG-1/Brm-associated factor subunit A(gene name synonym)|uniprotkb:BRG1-associated factor 60A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476547|imex:IM-26985-531 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001273455.1|ensembl:ENSP00000215115|ensembl:ENST00000380317|ensembl:ENSP00000369674|ensembl:ENSG00000099385(gene)|ensembl:ENST00000215115(transcript)|go:"GO:0006915"(apoptotic process)|interpro:IPR006804(BCL7, N-terminal)|mint:Q8WUZ0|refseq:NP_004756.2 ensembl:ENSG00000066117(gene)|ensembl:ENST00000394963(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048096"|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071564"(npBAF complex)|refseq:NP_003067.3|refseq:NP_620710.2|ensembl:ENST00000381513|ensembl:ENSP00000370924|ensembl:ENSP00000378414|go:"GO:0071565"(nBAF complex)|interpro:IPR003121(SWIB/MDM2)|interpro:IPR019835|interpro:IPR036885|interpro:IPR038041|mint:Q96GM5|rcsb pdb:6LTH|rcsb pdb:6LTJ|reactome:R-HSA-3214858|reactome:R-HSA-8939243|dip:DIP-33390N - comment:mint|comment:homomint|function:May play an anti-apoptotic role comment:"author score: 193" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:XuyDhxOhWHNVXmgi/WXLmCvKn409606 rogid:cwqYnl+J8glG8YjW1ps77Dd105Y9606 rigid:3fK9ES0QT5FEfdhSyeOzdmQEIDU false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H6W3 uniprotkb:Q13084 intact:EBI-2513645|ensembl:ENSP00000477507|uniprotkb:B4DT02 intact:EBI-723426|uniprotkb:Q4TT39|uniprotkb:Q96S26|uniprotkb:Q9BQD8|uniprotkb:Q9BR04|ensembl:ENSP00000199706|ensembl:ENSP00000374326|ensembl:ENSP00000497004|uniprotkb:B2RCM4|uniprotkb:D3DU46 psi-mi:riox1_human(display_long)|uniprotkb:RIOX1(gene name)|psi-mi:RIOX1(display_short)|uniprotkb:60S ribosomal protein L8 histidine hydroxylase(gene name synonym)|uniprotkb:Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66(gene name synonym)|uniprotkb:C14orf169(gene name synonym)|uniprotkb:Histone lysine demethylase NO66(gene name synonym)|uniprotkb:MAPJD(gene name synonym)|uniprotkb:Myc-associated protein with JmjC domain(gene name synonym)|uniprotkb:NO66(gene name synonym)|uniprotkb:Nucleolar protein 66(gene name synonym)|uniprotkb:Ribosomal oxygenase NO66(gene name synonym) psi-mi:rm28_human(display_long)|uniprotkb:Melanoma antigen p15(gene name synonym)|uniprotkb:MRPL28(gene name)|psi-mi:MRPL28(display_short)|uniprotkb:MAAT1(gene name synonym)|uniprotkb:Melanoma-associated antigen recognized by T-lymphocytes(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein bL28m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476748|imex:IM-26985-149 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000304061(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR013109(Cupin 4)|interpro:IPR039994|mint:Q9H6W3|rcsb pdb:4CCJ|rcsb pdb:4CCK|rcsb pdb:4CCM|rcsb pdb:4CCN|ensembl:ENSG00000170468(gene)|rcsb pdb:4CCO|rcsb pdb:4DIQ|rcsb pdb:4E4H|rcsb pdb:4Y33|rcsb pdb:4Y4R|rcsb pdb:4Y3O|refseq:NP_078920.2|dip:DIP-53768N refseq:NP_006419.2|rcsb pdb:3J7Y|ensembl:ENSG00000086504(gene)|ensembl:ENST00000199706(transcript)|ensembl:ENST00000389675(transcript)|ensembl:ENST00000648346(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|interpro:IPR026569|interpro:IPR034704|interpro:IPR037147|mint:Q13084|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:XP_011520653.1|refseq:XP_005255098.1|dip:DIP-61135N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RsTFUH3upRu11eleWymp6N7cEpM9606 rogid:rgjK24sQlABM210ZM7T9mT2wxKs9606 rigid:oYsyFjcRf+R68d/DGJdq4O6fuiE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H6W3 uniprotkb:P35232 intact:EBI-2513645|ensembl:ENSP00000477507|uniprotkb:B4DT02 intact:EBI-354213|uniprotkb:Q4VBQ0|uniprotkb:B4DY47|ensembl:ENSP00000300408|ensembl:ENSP00000393320|ensembl:ENSP00000422182|ensembl:ENSP00000425035|ensembl:ENSP00000426433|ensembl:ENSP00000479488|ensembl:ENSP00000484113 psi-mi:riox1_human(display_long)|uniprotkb:RIOX1(gene name)|psi-mi:RIOX1(display_short)|uniprotkb:60S ribosomal protein L8 histidine hydroxylase(gene name synonym)|uniprotkb:Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66(gene name synonym)|uniprotkb:C14orf169(gene name synonym)|uniprotkb:Histone lysine demethylase NO66(gene name synonym)|uniprotkb:MAPJD(gene name synonym)|uniprotkb:Myc-associated protein with JmjC domain(gene name synonym)|uniprotkb:NO66(gene name synonym)|uniprotkb:Nucleolar protein 66(gene name synonym)|uniprotkb:Ribosomal oxygenase NO66(gene name synonym) psi-mi:phb_human(display_long)|uniprotkb:PHB(gene name)|psi-mi:PHB(display_short)|uniprotkb:PHB1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476748|imex:IM-26985-149 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000304061(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR013109(Cupin 4)|interpro:IPR039994|mint:Q9H6W3|rcsb pdb:4CCJ|rcsb pdb:4CCK|rcsb pdb:4CCM|rcsb pdb:4CCN|ensembl:ENSG00000170468(gene)|rcsb pdb:4CCO|rcsb pdb:4DIQ|rcsb pdb:4E4H|rcsb pdb:4Y33|rcsb pdb:4Y4R|rcsb pdb:4Y3O|refseq:NP_078920.2|dip:DIP-53768N refseq:NP_001268426.1|refseq:NP_002625.1|refseq:NP_001268425.1|refseq:NP_001268644.1|refseq:XP_016880252.1|dip:DIP-24248N|ensembl:ENSG00000167085(gene)|ensembl:ENST00000300408(transcript)|ensembl:ENST00000419140(transcript)|ensembl:ENST00000504124(transcript)|ensembl:ENST00000511832(transcript)|ensembl:ENST00000512041(transcript)|ensembl:ENST00000614445(transcript)|ensembl:ENST00000617874(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001850"(complement component C3a binding)|go:"GO:0001851"(complement component C3b binding)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0016020"(membrane)|go:"GO:0016575"(histone deacetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031871"(proteinase activated receptor binding)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0035632"(mitochondrial prohibitin complex)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0042113"(B cell activation)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045917"(positive regulation of complement activation)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1990051"(activation of protein kinase C activity)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:P35232|rcsb pdb:1LU7|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802955|reactome:R-HSA-8949664|reactome:R-HSA-9649948 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RsTFUH3upRu11eleWymp6N7cEpM9606 rogid:aIJj/q/3JKXuEVRELjKJb2SjCKQ9606 rigid:oYsyFjcRf+R68d/DGJdq4O6fuiE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H6W3 uniprotkb:Q13459 intact:EBI-2513645|ensembl:ENSP00000477507|uniprotkb:B4DT02 intact:EBI-721429|uniprotkb:O75314|uniprotkb:Q9NUJ2|uniprotkb:Q9UHN0|ensembl:ENSP00000507803 psi-mi:riox1_human(display_long)|uniprotkb:RIOX1(gene name)|psi-mi:RIOX1(display_short)|uniprotkb:60S ribosomal protein L8 histidine hydroxylase(gene name synonym)|uniprotkb:Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66(gene name synonym)|uniprotkb:C14orf169(gene name synonym)|uniprotkb:Histone lysine demethylase NO66(gene name synonym)|uniprotkb:MAPJD(gene name synonym)|uniprotkb:Myc-associated protein with JmjC domain(gene name synonym)|uniprotkb:NO66(gene name synonym)|uniprotkb:Nucleolar protein 66(gene name synonym)|uniprotkb:Ribosomal oxygenase NO66(gene name synonym) psi-mi:myo9b_human(display_long)|uniprotkb:Unconventional myosin-9b(gene name synonym)|uniprotkb:MYO9B(gene name)|psi-mi:MYO9B(display_short)|uniprotkb:MYR5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476748|imex:IM-26985-149 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000304061(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR013109(Cupin 4)|interpro:IPR039994|mint:Q9H6W3|rcsb pdb:4CCJ|rcsb pdb:4CCK|rcsb pdb:4CCM|rcsb pdb:4CCN|ensembl:ENSG00000170468(gene)|rcsb pdb:4CCO|rcsb pdb:4DIQ|rcsb pdb:4E4H|rcsb pdb:4Y33|rcsb pdb:4Y4R|rcsb pdb:4Y3O|refseq:NP_078920.2|dip:DIP-53768N refseq:NP_004136.2|ensembl:ENSG00000099331(gene)|ensembl:ENST00000397274|ensembl:ENSP00000380444|ensembl:ENST00000595618|ensembl:ENSP00000471457|ensembl:ENSP00000507803|ensembl:ENST00000682292(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005938"(cell cortex)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0043531"(ADP binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048495"(Roundabout binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000159(Ras-association)|interpro:IPR000198(RhoGAP)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR028557|interpro:IPR029071|interpro:IPR036023|interpro:IPR036961|mint:Q13459|rcsb pdb:5C5S|rcsb pdb:5HPY|reactome:R-HSA-2029482|go:"GO:0007266"(Rho protein signal transduction)|reactome:R-HSA-8980692|reactome:R-HSA-8985586|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9035034|reactome:R-HSA-9664422 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RsTFUH3upRu11eleWymp6N7cEpM9606 rogid:eY7IjP7HSaKQaY4g77HcQYMPmyo9606 rigid:oYsyFjcRf+R68d/DGJdq4O6fuiE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H6W3 uniprotkb:Q8IXM3 intact:EBI-2513645|ensembl:ENSP00000477507|uniprotkb:B4DT02 intact:EBI-912501|uniprotkb:Q96Q49|ensembl:ENSP00000360498 psi-mi:riox1_human(display_long)|uniprotkb:RIOX1(gene name)|psi-mi:RIOX1(display_short)|uniprotkb:60S ribosomal protein L8 histidine hydroxylase(gene name synonym)|uniprotkb:Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66(gene name synonym)|uniprotkb:C14orf169(gene name synonym)|uniprotkb:Histone lysine demethylase NO66(gene name synonym)|uniprotkb:MAPJD(gene name synonym)|uniprotkb:Myc-associated protein with JmjC domain(gene name synonym)|uniprotkb:NO66(gene name synonym)|uniprotkb:Nucleolar protein 66(gene name synonym)|uniprotkb:Ribosomal oxygenase NO66(gene name synonym) psi-mi:rm41_human(display_long)|uniprotkb:MRPL27(gene name synonym)|uniprotkb:39S ribosomal protein L27 homolog(gene name synonym)|uniprotkb:MRP-L27 homolog(gene name synonym)|uniprotkb:Bcl-2-interacting mitochondrial ribosomal protein L41(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 3 protein(gene name synonym)|uniprotkb:MRPL41(gene name)|psi-mi:MRPL41(display_short)|uniprotkb:BMRP(gene name synonym)|uniprotkb:RPML27(gene name synonym)|uniprotkb:PIG3(orf name)|uniprotkb:Mitochondrial large ribosomal subunit protein mL41(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476748|imex:IM-26985-149 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000304061(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR013109(Cupin 4)|interpro:IPR039994|mint:Q9H6W3|rcsb pdb:4CCJ|rcsb pdb:4CCK|rcsb pdb:4CCM|rcsb pdb:4CCN|ensembl:ENSG00000170468(gene)|rcsb pdb:4CCO|rcsb pdb:4DIQ|rcsb pdb:4E4H|rcsb pdb:4Y33|rcsb pdb:4Y4R|rcsb pdb:4Y3O|refseq:NP_078920.2|dip:DIP-53768N refseq:NP_115866.1|ensembl:ENSG00000182154(gene)|ensembl:ENST00000371443(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR019189|mint:Q8IXM3|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RsTFUH3upRu11eleWymp6N7cEpM9606 rogid:1qftd9Vr6Rsymp6hgM29FeOvChA9606 rigid:oYsyFjcRf+R68d/DGJdq4O6fuiE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H6W3 uniprotkb:O75251 intact:EBI-2513645|ensembl:ENSP00000477507|uniprotkb:B4DT02 intact:EBI-719652|uniprotkb:Q2T9H7|uniprotkb:Q9BV17|ensembl:ENSP00000233627|uniprotkb:B3KRI2 psi-mi:riox1_human(display_long)|uniprotkb:RIOX1(gene name)|psi-mi:RIOX1(display_short)|uniprotkb:60S ribosomal protein L8 histidine hydroxylase(gene name synonym)|uniprotkb:Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66(gene name synonym)|uniprotkb:C14orf169(gene name synonym)|uniprotkb:Histone lysine demethylase NO66(gene name synonym)|uniprotkb:MAPJD(gene name synonym)|uniprotkb:Myc-associated protein with JmjC domain(gene name synonym)|uniprotkb:NO66(gene name synonym)|uniprotkb:Nucleolar protein 66(gene name synonym)|uniprotkb:Ribosomal oxygenase NO66(gene name synonym) psi-mi:ndus7_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase 20 kDa subunit(gene name synonym)|uniprotkb:Complex I-20kD(gene name synonym)|uniprotkb:PSST subunit(gene name synonym)|uniprotkb:NDUFS7(gene name)|psi-mi:NDUFS7(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476748|imex:IM-26985-149 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000304061(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR013109(Cupin 4)|interpro:IPR039994|mint:Q9H6W3|rcsb pdb:4CCJ|rcsb pdb:4CCK|rcsb pdb:4CCM|rcsb pdb:4CCN|ensembl:ENSG00000170468(gene)|rcsb pdb:4CCO|rcsb pdb:4DIQ|rcsb pdb:4E4H|rcsb pdb:4Y33|rcsb pdb:4Y4R|rcsb pdb:4Y3O|refseq:NP_078920.2|dip:DIP-53768N refseq:NP_077718.3|ensembl:ENSG00000115286(gene)|ensembl:ENST00000233627(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0009060"(aerobic respiration)|go:"GO:0015990"(electron transport coupled proton transport)|go:"GO:0016655"("oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor")|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046872"(metal ion binding)|go:"GO:0048038"(quinone binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|go:"GO:0097060"(synaptic membrane)|interpro:IPR006137(NADH ubiquinone oxidoreductase, 20 kDa subunit)|interpro:IPR006138("NADH dehydrogenase (ubiquinone), 20 kDa subunit")|mint:O75251|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RsTFUH3upRu11eleWymp6N7cEpM9606 rogid:DtNXT30ApcGKwTJSdNNwHd/q3+09606 rigid:oYsyFjcRf+R68d/DGJdq4O6fuiE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H6W3 uniprotkb:Q13015 intact:EBI-2513645|ensembl:ENSP00000477507|uniprotkb:B4DT02 intact:EBI-6269719|ensembl:ENSP00000357917 psi-mi:riox1_human(display_long)|uniprotkb:RIOX1(gene name)|psi-mi:RIOX1(display_short)|uniprotkb:60S ribosomal protein L8 histidine hydroxylase(gene name synonym)|uniprotkb:Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66(gene name synonym)|uniprotkb:C14orf169(gene name synonym)|uniprotkb:Histone lysine demethylase NO66(gene name synonym)|uniprotkb:MAPJD(gene name synonym)|uniprotkb:Myc-associated protein with JmjC domain(gene name synonym)|uniprotkb:NO66(gene name synonym)|uniprotkb:Nucleolar protein 66(gene name synonym)|uniprotkb:Ribosomal oxygenase NO66(gene name synonym) psi-mi:af1q_human(display_long)|uniprotkb:MLLT11(gene name)|psi-mi:MLLT11(display_short)|uniprotkb:AF1Q(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476748|imex:IM-26985-149 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000304061(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR013109(Cupin 4)|interpro:IPR039994|mint:Q9H6W3|rcsb pdb:4CCJ|rcsb pdb:4CCK|rcsb pdb:4CCM|rcsb pdb:4CCN|ensembl:ENSG00000170468(gene)|rcsb pdb:4CCO|rcsb pdb:4DIQ|rcsb pdb:4E4H|rcsb pdb:4Y33|rcsb pdb:4Y4R|rcsb pdb:4Y3O|refseq:NP_078920.2|dip:DIP-53768N ensembl:ENSG00000213190(gene)|ensembl:ENST00000368921(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR026778|interpro:IPR033461|mint:Q13015|refseq:NP_006809.1 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RsTFUH3upRu11eleWymp6N7cEpM9606 rogid:23mnJAG1OcDgM7eT2rTi1Gv0ZgA9606 rigid:oYsyFjcRf+R68d/DGJdq4O6fuiE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H6W3 uniprotkb:Q9BWF3 intact:EBI-2513645|ensembl:ENSP00000477507|uniprotkb:B4DT02 intact:EBI-2856454|uniprotkb:B3KUN0|uniprotkb:Q8WU85|uniprotkb:Q6P1P2|uniprotkb:O02916|uniprotkb:Q4VC48|uniprotkb:B4E1U0|uniprotkb:E7EQS3|ensembl:ENSP00000309166|ensembl:ENSP00000386561|ensembl:ENSP00000386894 psi-mi:riox1_human(display_long)|uniprotkb:RIOX1(gene name)|psi-mi:RIOX1(display_short)|uniprotkb:60S ribosomal protein L8 histidine hydroxylase(gene name synonym)|uniprotkb:Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66(gene name synonym)|uniprotkb:C14orf169(gene name synonym)|uniprotkb:Histone lysine demethylase NO66(gene name synonym)|uniprotkb:MAPJD(gene name synonym)|uniprotkb:Myc-associated protein with JmjC domain(gene name synonym)|uniprotkb:NO66(gene name synonym)|uniprotkb:Nucleolar protein 66(gene name synonym)|uniprotkb:Ribosomal oxygenase NO66(gene name synonym) psi-mi:rbm4_human(display_long)|uniprotkb:RBM4(gene name)|psi-mi:RBM4(display_short)|uniprotkb:RBM4A(gene name synonym)|uniprotkb:Lark homolog(gene name synonym)|uniprotkb:RNA-binding motif protein 4(gene name synonym)|uniprotkb:RNA-binding motif protein 4a(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476748|imex:IM-26985-149 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000304061(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR013109(Cupin 4)|interpro:IPR039994|mint:Q9H6W3|rcsb pdb:4CCJ|rcsb pdb:4CCK|rcsb pdb:4CCM|rcsb pdb:4CCN|ensembl:ENSG00000170468(gene)|rcsb pdb:4CCO|rcsb pdb:4DIQ|rcsb pdb:4E4H|rcsb pdb:4Y33|rcsb pdb:4Y4R|rcsb pdb:4Y3O|refseq:NP_078920.2|dip:DIP-53768N refseq:NP_001185772.1|refseq:NP_002887.2|refseq:NP_001185773.1|dip:DIP-44199N|ensembl:ENSG00000173933(gene)|ensembl:ENST00000310092(transcript)|ensembl:ENST00000408993(transcript)|ensembl:ENST00000409406(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0002190"(cap-independent translational initiation)|go:"GO:0002192"(IRES-dependent translational initiation of linear mRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030332"(cyclin binding)|go:"GO:0032055"(negative regulation of translation in response to stress)|go:"GO:0035198"(miRNA binding)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051149"(positive regulation of muscle cell differentiation)|go:"GO:0097157"(pre-mRNA intronic binding)|go:"GO:0097158"(pre-mRNA intronic pyrimidine-rich binding)|go:"GO:0097167"(circadian regulation of translation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR034897|interpro:IPR034898|interpro:IPR035979|mint:Q9BWF3|rcsb pdb:2DNQ|reactome:R-HSA-400253|interpro:IPR012677(Nucleotide-binding, alpha-beta plait) - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RsTFUH3upRu11eleWymp6N7cEpM9606 rogid:hbW6dv/AEWQz3mWvA2/9n8h/bbA9606 rigid:oYsyFjcRf+R68d/DGJdq4O6fuiE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H6W3 uniprotkb:Q9HD33 intact:EBI-2513645|ensembl:ENSP00000477507|uniprotkb:B4DT02 intact:EBI-2560181|uniprotkb:Q8N5D1|uniprotkb:Q6XRG1|ensembl:ENSP00000417602 psi-mi:riox1_human(display_long)|uniprotkb:RIOX1(gene name)|psi-mi:RIOX1(display_short)|uniprotkb:60S ribosomal protein L8 histidine hydroxylase(gene name synonym)|uniprotkb:Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66(gene name synonym)|uniprotkb:C14orf169(gene name synonym)|uniprotkb:Histone lysine demethylase NO66(gene name synonym)|uniprotkb:MAPJD(gene name synonym)|uniprotkb:Myc-associated protein with JmjC domain(gene name synonym)|uniprotkb:NO66(gene name synonym)|uniprotkb:Nucleolar protein 66(gene name synonym)|uniprotkb:Ribosomal oxygenase NO66(gene name synonym) psi-mi:rm47_human(display_long)|uniprotkb:MRPL47(gene name)|psi-mi:MRPL47(display_short)|uniprotkb:NCM1(gene name synonym)|uniprotkb:Nasopharyngeal carcinoma metastasis-related protein 1(gene name synonym)|uniprotkb:CGI-204(orf name)|uniprotkb:Mitochondrial large ribosomal subunit protein uL29m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476748|imex:IM-26985-149 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000304061(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR013109(Cupin 4)|interpro:IPR039994|mint:Q9H6W3|rcsb pdb:4CCJ|rcsb pdb:4CCK|rcsb pdb:4CCM|rcsb pdb:4CCN|ensembl:ENSG00000170468(gene)|rcsb pdb:4CCO|rcsb pdb:4DIQ|rcsb pdb:4E4H|rcsb pdb:4Y33|rcsb pdb:4Y4R|rcsb pdb:4Y3O|refseq:NP_078920.2|dip:DIP-53768N refseq:NP_065142.2|refseq:NP_817125.1|ensembl:ENSG00000136522(gene)|ensembl:ENST00000476781(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR010729(Ribosomal protein L47, mitochondrial)|interpro:IPR038340|mint:Q9HD33|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU3|rcsb pdb:6NU2|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RsTFUH3upRu11eleWymp6N7cEpM9606 rogid:Zwk2kFYyc2Efry0CU19e8o7GEW89606 rigid:oYsyFjcRf+R68d/DGJdq4O6fuiE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H6W3 uniprotkb:Q9Y312 intact:EBI-2513645|ensembl:ENSP00000477507|uniprotkb:B4DT02 intact:EBI-748721|uniprotkb:Q9H4F9|uniprotkb:Q9P1P3|uniprotkb:Q9UFK9|uniprotkb:E1P5S7|ensembl:ENSP00000313674|ensembl:ENSP00000363043|ensembl:ENSP00000505061|ensembl:ENSP00000505295|ensembl:ENSP00000505405|ensembl:ENSP00000506185|ensembl:ENSP00000506354 psi-mi:riox1_human(display_long)|uniprotkb:RIOX1(gene name)|psi-mi:RIOX1(display_short)|uniprotkb:60S ribosomal protein L8 histidine hydroxylase(gene name synonym)|uniprotkb:Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66(gene name synonym)|uniprotkb:C14orf169(gene name synonym)|uniprotkb:Histone lysine demethylase NO66(gene name synonym)|uniprotkb:MAPJD(gene name synonym)|uniprotkb:Myc-associated protein with JmjC domain(gene name synonym)|uniprotkb:NO66(gene name synonym)|uniprotkb:Nucleolar protein 66(gene name synonym)|uniprotkb:Ribosomal oxygenase NO66(gene name synonym) psi-mi:aar2_human(display_long)|uniprotkb:AAR2(gene name)|psi-mi:AAR2(display_short)|uniprotkb:AAR2 splicing factor homolog(gene name synonym)|uniprotkb:C20orf4(gene name synonym)|uniprotkb:CGI-23(orf name)|uniprotkb:PRO0225(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476748|imex:IM-26985-149 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000304061(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR013109(Cupin 4)|interpro:IPR039994|mint:Q9H6W3|rcsb pdb:4CCJ|rcsb pdb:4CCK|rcsb pdb:4CCM|rcsb pdb:4CCN|ensembl:ENSG00000170468(gene)|rcsb pdb:4CCO|rcsb pdb:4DIQ|rcsb pdb:4E4H|rcsb pdb:4Y33|rcsb pdb:4Y4R|rcsb pdb:4Y3O|refseq:NP_078920.2|dip:DIP-53768N refseq:NP_056326.2|refseq:NP_001258803.1|refseq:XP_006723833.1|refseq:XP_011527065.1|refseq:XP_011527064.1|ensembl:ENSG00000131043(gene)|ensembl:ENST00000320849(transcript)|ensembl:ENST00000373932(transcript)|ensembl:ENST00000679667(transcript)|ensembl:ENST00000680247(transcript)|ensembl:ENST00000680639(transcript)|ensembl:ENST00000680811(transcript)|ensembl:ENST00000680933(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|interpro:IPR007946(AAR2)|interpro:IPR033647|interpro:IPR033648|interpro:IPR038514|interpro:IPR038516|mint:Q9Y312 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RsTFUH3upRu11eleWymp6N7cEpM9606 rogid:mvbhGa01cuYd3fN8vbbXdzS0mSg9606 rigid:oYsyFjcRf+R68d/DGJdq4O6fuiE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H6W3 uniprotkb:Q96A35 intact:EBI-2513645|ensembl:ENSP00000477507|uniprotkb:B4DT02 intact:EBI-1045743|uniprotkb:Q53G65|uniprotkb:Q53HT0|uniprotkb:Q5SYZ9|uniprotkb:Q5SZ00|uniprotkb:Q5SZ02|uniprotkb:Q96Q70|uniprotkb:Q9H7G3|uniprotkb:D3DVC8|intact:EBI-2560246|ensembl:ENSP00000354525|ensembl:ENSP00000357194 psi-mi:riox1_human(display_long)|uniprotkb:RIOX1(gene name)|psi-mi:RIOX1(display_short)|uniprotkb:60S ribosomal protein L8 histidine hydroxylase(gene name synonym)|uniprotkb:Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66(gene name synonym)|uniprotkb:C14orf169(gene name synonym)|uniprotkb:Histone lysine demethylase NO66(gene name synonym)|uniprotkb:MAPJD(gene name synonym)|uniprotkb:Myc-associated protein with JmjC domain(gene name synonym)|uniprotkb:NO66(gene name synonym)|uniprotkb:Nucleolar protein 66(gene name synonym)|uniprotkb:Ribosomal oxygenase NO66(gene name synonym) psi-mi:rm24_human(display_long)|uniprotkb:MRPL24(gene name)|psi-mi:MRPL24(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein uL24m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476748|imex:IM-26985-149 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000304061(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR013109(Cupin 4)|interpro:IPR039994|mint:Q9H6W3|rcsb pdb:4CCJ|rcsb pdb:4CCK|rcsb pdb:4CCM|rcsb pdb:4CCN|ensembl:ENSG00000170468(gene)|rcsb pdb:4CCO|rcsb pdb:4DIQ|rcsb pdb:4E4H|rcsb pdb:4Y33|rcsb pdb:4Y4R|rcsb pdb:4Y3O|refseq:NP_078920.2|dip:DIP-53768N refseq:NP_078816.2|refseq:NP_663781.1|ensembl:ENSG00000143314(gene)|ensembl:ENST00000361531(transcript)|ensembl:ENST00000368211(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|interpro:IPR003256(Ribosomal protein L24)|interpro:IPR005824(KOW)|interpro:IPR005825(Ribosomal protein L24/L26, conserved site)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041988|mint:Q96A35|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:6ZSE|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:XP_011508283.1|refseq:XP_011508284.1 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RsTFUH3upRu11eleWymp6N7cEpM9606 rogid:TVDcxc2+oUe0eez+iQPW5HWBwdI9606 rigid:oYsyFjcRf+R68d/DGJdq4O6fuiE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H6W3 uniprotkb:P60468 intact:EBI-2513645|ensembl:ENSP00000477507|uniprotkb:B4DT02 intact:EBI-1788819|uniprotkb:P38390|uniprotkb:P38391|uniprotkb:Q6IBC1|ensembl:ENSP00000223641 psi-mi:riox1_human(display_long)|uniprotkb:RIOX1(gene name)|psi-mi:RIOX1(display_short)|uniprotkb:60S ribosomal protein L8 histidine hydroxylase(gene name synonym)|uniprotkb:Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66(gene name synonym)|uniprotkb:C14orf169(gene name synonym)|uniprotkb:Histone lysine demethylase NO66(gene name synonym)|uniprotkb:MAPJD(gene name synonym)|uniprotkb:Myc-associated protein with JmjC domain(gene name synonym)|uniprotkb:NO66(gene name synonym)|uniprotkb:Nucleolar protein 66(gene name synonym)|uniprotkb:Ribosomal oxygenase NO66(gene name synonym) psi-mi:sc61b_human(display_long)|uniprotkb:SEC61B(gene name)|psi-mi:SEC61B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476748|imex:IM-26985-149 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000304061(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR013109(Cupin 4)|interpro:IPR039994|mint:Q9H6W3|rcsb pdb:4CCJ|rcsb pdb:4CCK|rcsb pdb:4CCM|rcsb pdb:4CCN|ensembl:ENSG00000170468(gene)|rcsb pdb:4CCO|rcsb pdb:4DIQ|rcsb pdb:4E4H|rcsb pdb:4Y33|rcsb pdb:4Y4R|rcsb pdb:4Y3O|refseq:NP_078920.2|dip:DIP-53768N refseq:NP_006799.1|dip:DIP-40997N|ensembl:ENSG00000106803(gene)|ensembl:ENST00000223641(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031205"(endoplasmic reticulum Sec complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048408"(epidermal growth factor binding)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR030671|mint:P60468|rcsb pdb:6W6L|reactome:R-HSA-1236974|reactome:R-HSA-1799339|reactome:R-HSA-9609523 - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RsTFUH3upRu11eleWymp6N7cEpM9606 rogid:hmJI1Sb6h53BUHLoKTSJPyTbPF89606 rigid:oYsyFjcRf+R68d/DGJdq4O6fuiE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H6W3 uniprotkb:Q9HCN8 intact:EBI-2513645|ensembl:ENSP00000477507|uniprotkb:B4DT02 intact:EBI-2339921|uniprotkb:Q9BRI5|uniprotkb:A2RUD3|ensembl:ENSP00000248958 psi-mi:riox1_human(display_long)|uniprotkb:RIOX1(gene name)|psi-mi:RIOX1(display_short)|uniprotkb:60S ribosomal protein L8 histidine hydroxylase(gene name synonym)|uniprotkb:Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66(gene name synonym)|uniprotkb:C14orf169(gene name synonym)|uniprotkb:Histone lysine demethylase NO66(gene name synonym)|uniprotkb:MAPJD(gene name synonym)|uniprotkb:Myc-associated protein with JmjC domain(gene name synonym)|uniprotkb:NO66(gene name synonym)|uniprotkb:Nucleolar protein 66(gene name synonym)|uniprotkb:Ribosomal oxygenase NO66(gene name synonym) psi-mi:sdf2l_human(display_long)|uniprotkb:SDF2L1(gene name)|psi-mi:SDF2L1(display_short)|uniprotkb:PWP1-interacting protein 8(gene name synonym)|uniprotkb:UNQ1941/PRO4424(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476748|imex:IM-26985-149 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000304061(transcript)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR013109(Cupin 4)|interpro:IPR039994|mint:Q9H6W3|rcsb pdb:4CCJ|rcsb pdb:4CCK|rcsb pdb:4CCM|rcsb pdb:4CCN|ensembl:ENSG00000170468(gene)|rcsb pdb:4CCO|rcsb pdb:4DIQ|rcsb pdb:4E4H|rcsb pdb:4Y33|rcsb pdb:4Y4R|rcsb pdb:4Y3O|refseq:NP_078920.2|dip:DIP-53768N refseq:NP_071327.2|ensembl:ENSG00000128228(gene)|ensembl:ENST00000248958(transcript)|go:"GO:0004169"(dolichyl-phosphate-mannose-protein mannosyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0035269"(protein O-linked mannosylation)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0071712"(ER-associated misfolded protein catabolic process)|go:"GO:0101031"(chaperone complex)|interpro:IPR016093(MIR motif)|interpro:IPR036300|mint:Q9HCN8 - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RsTFUH3upRu11eleWymp6N7cEpM9606 rogid:0vAPKCqCGpCARkmy7ZsTccxScgk9606 rigid:oYsyFjcRf+R68d/DGJdq4O6fuiE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95696 uniprotkb:Q14011 intact:EBI-714754|uniprotkb:A6ZJA4|ensembl:ENSP00000216267|ensembl:ENSP00000384076 intact:EBI-538850|uniprotkb:B4E2X2|intact:EBI-10980353|uniprotkb:B3KT17|ensembl:ENSP00000322887|ensembl:ENSP00000465779|ensembl:ENSP00000466110|ensembl:ENSP00000466207|ensembl:ENSP00000468788 psi-mi:brd1_human(display_long)|uniprotkb:BR140-like protein(gene name synonym)|uniprotkb:BRD1(gene name)|psi-mi:BRD1(display_short)|uniprotkb:BRL(gene name synonym)|uniprotkb:BRPF2(gene name synonym)|uniprotkb:Bromodomain and PHD finger-containing protein 2(gene name synonym) psi-mi:cirbp_human(display_long)|uniprotkb:Glycine-rich RNA-binding protein CIRP(gene name synonym)|uniprotkb:A18 hnRNP(gene name synonym)|uniprotkb:CIRBP(gene name)|psi-mi:CIRBP(display_short)|uniprotkb:A18HNRNP(gene name synonym)|uniprotkb:CIRP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476670|imex:IM-26985-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0036409"(histone H3-K14 acetyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051602"(response to electrical stimulus)|ensembl:ENSG00000100425(gene)|ensembl:ENST00000216267(transcript)|ensembl:ENST00000404034(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0016607"(nuclear speck)|go:"GO:0030425"(dendrite)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042004|interpro:IPR042009|mint:O95696|rcsb pdb:2KU3|rcsb pdb:2L43|rcsb pdb:2LQ6|rcsb pdb:3LYI|rcsb pdb:3RCW|rcsb pdb:4Z02|rcsb pdb:5AME|rcsb pdb:5AMF|rcsb pdb:5FG6|rcsb pdb:5GK9|rcsb pdb:5N49|rcsb pdb:5PNX|rcsb pdb:5PNY|rcsb pdb:5PNZ|rcsb pdb:5PO0|rcsb pdb:5PO1|rcsb pdb:5PO2|rcsb pdb:5PO3|rcsb pdb:5PO4|rcsb pdb:5PO5|rcsb pdb:5PO6|rcsb pdb:5PO7|rcsb pdb:5PO8|rcsb pdb:5PO9|rcsb pdb:5POA|rcsb pdb:5POB|rcsb pdb:5POC|rcsb pdb:5POD|rcsb pdb:5POE|rcsb pdb:5POF|rcsb pdb:5POG|rcsb pdb:5POH|rcsb pdb:5POI|rcsb pdb:5POJ|rcsb pdb:5POK|rcsb pdb:5POL|rcsb pdb:5POM|rcsb pdb:5PON|rcsb pdb:5POO|rcsb pdb:5POP|rcsb pdb:5POQ|refseq:XP_016884206.1|rcsb pdb:5POR|rcsb pdb:5POS|rcsb pdb:5POT|rcsb pdb:5POU|rcsb pdb:5POV|rcsb pdb:5POW|rcsb pdb:5POX|rcsb pdb:5POY|rcsb pdb:5POZ|rcsb pdb:5PP0|rcsb pdb:5PP1|rcsb pdb:5PP2|rcsb pdb:5PP3|rcsb pdb:5PP4|rcsb pdb:5PP5|rcsb pdb:5PP6|rcsb pdb:5PP7|rcsb pdb:5PP8|rcsb pdb:5PP9|rcsb pdb:5PPA|rcsb pdb:5PPB|rcsb pdb:5PPC|rcsb pdb:5PPD|rcsb pdb:5PPE|rcsb pdb:5PPF|rcsb pdb:5PPG|rcsb pdb:5PPH|rcsb pdb:5PPI|rcsb pdb:5PPJ|rcsb pdb:5PPK|rcsb pdb:5PPL|rcsb pdb:5PPM|rcsb pdb:5PPN|rcsb pdb:5PPO|rcsb pdb:5PPP|rcsb pdb:5PPQ|rcsb pdb:5PPR|rcsb pdb:5PPS|rcsb pdb:5PPT|rcsb pdb:5PPU|rcsb pdb:5PPV|rcsb pdb:5PPW|rcsb pdb:5PPX|rcsb pdb:5PPY|rcsb pdb:5PPZ|rcsb pdb:5PQ0|rcsb pdb:5PQ1|rcsb pdb:5PQ2|rcsb pdb:5PQ3|rcsb pdb:5PQ4|rcsb pdb:5PQ5|rcsb pdb:5PQ6|rcsb pdb:5PQ7|rcsb pdb:5PQ8|rcsb pdb:5PQ9|rcsb pdb:5PQA|rcsb pdb:5PQB|rcsb pdb:5PQC|rcsb pdb:5PQD|rcsb pdb:5PQE|rcsb pdb:5PQF|rcsb pdb:5PQG|rcsb pdb:5PQH|rcsb pdb:5PQI|rcsb pdb:5PQJ|rcsb pdb:5PQK|rcsb pdb:5PQL|rcsb pdb:5PQM|rcsb pdb:5PQN|rcsb pdb:5PQO|rcsb pdb:5PQP|rcsb pdb:5PQQ|rcsb pdb:5PQR|rcsb pdb:5PQS|rcsb pdb:5PQT|rcsb pdb:5PQU|rcsb pdb:5PQV|rcsb pdb:5PQW|rcsb pdb:5PQX|rcsb pdb:5PQY|rcsb pdb:5PQZ|rcsb pdb:5PR0|rcsb pdb:5PR1|rcsb pdb:5PR2|rcsb pdb:5PR4|rcsb pdb:5PR5|rcsb pdb:5PR6|rcsb pdb:5PR7|rcsb pdb:5PR8|rcsb pdb:5PST|rcsb pdb:5PR9|rcsb pdb:5PRA|rcsb pdb:5PRB|rcsb pdb:5PRD|rcsb pdb:5PRE|rcsb pdb:5PRF|rcsb pdb:5PRG|rcsb pdb:5PRH|rcsb pdb:5PRI|rcsb pdb:5PRJ|rcsb pdb:5PRK|rcsb pdb:5PRL|rcsb pdb:5PRM|rcsb pdb:5PRO|rcsb pdb:5PRP|rcsb pdb:5PRQ|rcsb pdb:5PRR|rcsb pdb:5PRS|rcsb pdb:5PRT|rcsb pdb:5PRU|rcsb pdb:5PRV|rcsb pdb:5PRW|rcsb pdb:5PRX|rcsb pdb:5PRY|rcsb pdb:5PRZ|rcsb pdb:5PS0|rcsb pdb:5PS1|rcsb pdb:5PS2|rcsb pdb:5PS3|rcsb pdb:5PS4|rcsb pdb:5PS5|rcsb pdb:5PS6|rcsb pdb:5PS7|rcsb pdb:5PS8|rcsb pdb:5PS9|rcsb pdb:5PSA|rcsb pdb:5PSB|rcsb pdb:5PSC|rcsb pdb:5PSD|rcsb pdb:5PSE|rcsb pdb:5PSF|rcsb pdb:5PSG|rcsb pdb:5PSH|rcsb pdb:5PSI|rcsb pdb:5PSJ|rcsb pdb:5PSK|rcsb pdb:5PSL|rcsb pdb:5PSM|rcsb pdb:5PSN|rcsb pdb:5PSO|rcsb pdb:5PSP|rcsb pdb:5PSQ|rcsb pdb:5PSR|rcsb pdb:5PSS|rcsb pdb:5PSU|rcsb pdb:5PSV|rcsb pdb:5PSW|rcsb pdb:5PSX|rcsb pdb:5PSY|rcsb pdb:5PSZ|rcsb pdb:5PT0|rcsb pdb:5PT1|rcsb pdb:5PT2|rcsb pdb:5PT3|rcsb pdb:5PT4|rcsb pdb:5PT5|rcsb pdb:5PT6|rcsb pdb:5PT7|rcsb pdb:5PT8|rcsb pdb:5PT9|rcsb pdb:5PTA|rcsb pdb:5PTB|rcsb pdb:5PTC|rcsb pdb:5PTE|rcsb pdb:5PTF|rcsb pdb:5PTG|rcsb pdb:5PTH|rcsb pdb:5PTJ|rcsb pdb:5PTK|rcsb pdb:5PTL|rcsb pdb:5PTM|rcsb pdb:5PTN|rcsb pdb:5PTO|rcsb pdb:5PTQ|rcsb pdb:5PTR|rcsb pdb:5PTS|rcsb pdb:5PTT|rcsb pdb:5PTU|rcsb pdb:5PTV|rcsb pdb:5PTW|rcsb pdb:5PTX|rcsb pdb:5PTY|rcsb pdb:5PTZ|rcsb pdb:5PU0|rcsb pdb:5PU1|rcsb pdb:5PU2|rcsb pdb:5PU3|rcsb pdb:5PU4|rcsb pdb:5PU5|rcsb pdb:5PU6|rcsb pdb:5PU7|rcsb pdb:5PU8|rcsb pdb:5PU9|rcsb pdb:5PUA|rcsb pdb:5PUB|rcsb pdb:5PUC|rcsb pdb:5PUD|rcsb pdb:5PUE|rcsb pdb:5PUF|rcsb pdb:5PUG|rcsb pdb:5PUH|rcsb pdb:5PUI|rcsb pdb:5PUJ|rcsb pdb:5PUK|rcsb pdb:5PUL|rcsb pdb:5PUM|rcsb pdb:5PUN|rcsb pdb:5PUO|rcsb pdb:5PUP|rcsb pdb:5PUQ|rcsb pdb:5PUR|rcsb pdb:5PUS|rcsb pdb:5PUT|rcsb pdb:5PUU|rcsb pdb:5PUV|rcsb pdb:5PUW|rcsb pdb:5PUX|rcsb pdb:5PUY|rcsb pdb:5PUZ|rcsb pdb:5PV0|rcsb pdb:5PV1|rcsb pdb:5PV2|rcsb pdb:5PV3|rcsb pdb:5PV4|rcsb pdb:5PV5|rcsb pdb:5PV6|rcsb pdb:5PV7|rcsb pdb:5PV8|rcsb pdb:5PV9|rcsb pdb:5PVA|rcsb pdb:5PVB|rcsb pdb:5PVC|rcsb pdb:5PVD|rcsb pdb:5PVE|rcsb pdb:5PVF|rcsb pdb:5PVG|rcsb pdb:5PVH|rcsb pdb:5PVI|rcsb pdb:5PVJ|rcsb pdb:5PVK|rcsb pdb:5PVL|rcsb pdb:5PVM|rcsb pdb:5PVN|rcsb pdb:5PVO|rcsb pdb:5PVP|rcsb pdb:5PVQ|rcsb pdb:5PVR|rcsb pdb:5PVS|rcsb pdb:5PVT|rcsb pdb:5PVU|rcsb pdb:5PVV|rcsb pdb:5PVW|rcsb pdb:5PVX|rcsb pdb:5PVY|rcsb pdb:5PVZ|rcsb pdb:5PW0|rcsb pdb:5PW1|rcsb pdb:5PW2|rcsb pdb:5PW3|rcsb pdb:5PW4|rcsb pdb:5PW5|rcsb pdb:5PW6|rcsb pdb:5PW7|rcsb pdb:5PW8|rcsb pdb:5PW9|rcsb pdb:5PWA|rcsb pdb:5PWB|rcsb pdb:6IN2|rcsb pdb:6MAJ|rcsb pdb:6MAK|rcsb pdb:7LH9|reactome:R-HSA-3214847|reactome:R-HSA-6804758|refseq:NP_001291737.1|refseq:NP_001291738.1|refseq:XP_016884204.1|refseq:XP_016884205.1 refseq:NP_001271.1|refseq:XP_006722700.1|refseq:NP_001287744.1|refseq:NP_001287758.1|ensembl:ENSG00000099622(gene)|ensembl:ENST00000320936(transcript)|ensembl:ENST00000585630(transcript)|ensembl:ENST00000586472(transcript)|ensembl:ENST00000588030(transcript)|ensembl:ENST00000588090(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0009409"(response to cold)|go:"GO:0009411"(response to UV)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030371"(translation repressor activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034278|interpro:IPR035979|mint:Q14011|rcsb pdb:1X5S|rcsb pdb:5TBX - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:P/L2yjwT2CYr7rO64cYcdahm2z09606 rogid:nm6/8k5Pw1AnoXsSw9cazJkL49U9606 rigid:61ptXJ352/6k7OWcQc+mQW/uIAg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95696 uniprotkb:Q92878 intact:EBI-714754|uniprotkb:A6ZJA4|ensembl:ENSP00000216267|ensembl:ENSP00000384076 intact:EBI-495494|uniprotkb:O43254|uniprotkb:Q6GMT7|uniprotkb:Q6P5X3|uniprotkb:Q9UP86|uniprotkb:B9EGF5|ensembl:ENSP00000368100 psi-mi:brd1_human(display_long)|uniprotkb:BR140-like protein(gene name synonym)|uniprotkb:BRD1(gene name)|psi-mi:BRD1(display_short)|uniprotkb:BRL(gene name synonym)|uniprotkb:BRPF2(gene name synonym)|uniprotkb:Bromodomain and PHD finger-containing protein 2(gene name synonym) psi-mi:rad50_human(display_long)|uniprotkb:RAD50(gene name)|psi-mi:RAD50(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476670|imex:IM-26985-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0036409"(histone H3-K14 acetyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051602"(response to electrical stimulus)|ensembl:ENSG00000100425(gene)|ensembl:ENST00000216267(transcript)|ensembl:ENST00000404034(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0016607"(nuclear speck)|go:"GO:0030425"(dendrite)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042004|interpro:IPR042009|mint:O95696|rcsb pdb:2KU3|rcsb pdb:2L43|rcsb pdb:2LQ6|rcsb pdb:3LYI|rcsb pdb:3RCW|rcsb pdb:4Z02|rcsb pdb:5AME|rcsb pdb:5AMF|rcsb pdb:5FG6|rcsb pdb:5GK9|rcsb pdb:5N49|rcsb pdb:5PNX|rcsb pdb:5PNY|rcsb pdb:5PNZ|rcsb pdb:5PO0|rcsb pdb:5PO1|rcsb pdb:5PO2|rcsb pdb:5PO3|rcsb pdb:5PO4|rcsb pdb:5PO5|rcsb pdb:5PO6|rcsb pdb:5PO7|rcsb pdb:5PO8|rcsb pdb:5PO9|rcsb pdb:5POA|rcsb pdb:5POB|rcsb pdb:5POC|rcsb pdb:5POD|rcsb pdb:5POE|rcsb pdb:5POF|rcsb pdb:5POG|rcsb pdb:5POH|rcsb pdb:5POI|rcsb pdb:5POJ|rcsb pdb:5POK|rcsb pdb:5POL|rcsb pdb:5POM|rcsb pdb:5PON|rcsb pdb:5POO|rcsb pdb:5POP|rcsb pdb:5POQ|refseq:XP_016884206.1|rcsb pdb:5POR|rcsb pdb:5POS|rcsb pdb:5POT|rcsb pdb:5POU|rcsb pdb:5POV|rcsb pdb:5POW|rcsb pdb:5POX|rcsb pdb:5POY|rcsb pdb:5POZ|rcsb pdb:5PP0|rcsb pdb:5PP1|rcsb pdb:5PP2|rcsb pdb:5PP3|rcsb pdb:5PP4|rcsb pdb:5PP5|rcsb pdb:5PP6|rcsb pdb:5PP7|rcsb pdb:5PP8|rcsb pdb:5PP9|rcsb pdb:5PPA|rcsb pdb:5PPB|rcsb pdb:5PPC|rcsb pdb:5PPD|rcsb pdb:5PPE|rcsb pdb:5PPF|rcsb pdb:5PPG|rcsb pdb:5PPH|rcsb pdb:5PPI|rcsb pdb:5PPJ|rcsb pdb:5PPK|rcsb pdb:5PPL|rcsb pdb:5PPM|rcsb pdb:5PPN|rcsb pdb:5PPO|rcsb pdb:5PPP|rcsb pdb:5PPQ|rcsb pdb:5PPR|rcsb pdb:5PPS|rcsb pdb:5PPT|rcsb pdb:5PPU|rcsb pdb:5PPV|rcsb pdb:5PPW|rcsb pdb:5PPX|rcsb pdb:5PPY|rcsb pdb:5PPZ|rcsb pdb:5PQ0|rcsb pdb:5PQ1|rcsb pdb:5PQ2|rcsb pdb:5PQ3|rcsb pdb:5PQ4|rcsb pdb:5PQ5|rcsb pdb:5PQ6|rcsb pdb:5PQ7|rcsb pdb:5PQ8|rcsb pdb:5PQ9|rcsb pdb:5PQA|rcsb pdb:5PQB|rcsb pdb:5PQC|rcsb pdb:5PQD|rcsb pdb:5PQE|rcsb pdb:5PQF|rcsb pdb:5PQG|rcsb pdb:5PQH|rcsb pdb:5PQI|rcsb pdb:5PQJ|rcsb pdb:5PQK|rcsb pdb:5PQL|rcsb pdb:5PQM|rcsb pdb:5PQN|rcsb pdb:5PQO|rcsb pdb:5PQP|rcsb pdb:5PQQ|rcsb pdb:5PQR|rcsb pdb:5PQS|rcsb pdb:5PQT|rcsb pdb:5PQU|rcsb pdb:5PQV|rcsb pdb:5PQW|rcsb pdb:5PQX|rcsb pdb:5PQY|rcsb pdb:5PQZ|rcsb pdb:5PR0|rcsb pdb:5PR1|rcsb pdb:5PR2|rcsb pdb:5PR4|rcsb pdb:5PR5|rcsb pdb:5PR6|rcsb pdb:5PR7|rcsb pdb:5PR8|rcsb pdb:5PST|rcsb pdb:5PR9|rcsb pdb:5PRA|rcsb pdb:5PRB|rcsb pdb:5PRD|rcsb pdb:5PRE|rcsb pdb:5PRF|rcsb pdb:5PRG|rcsb pdb:5PRH|rcsb pdb:5PRI|rcsb pdb:5PRJ|rcsb pdb:5PRK|rcsb pdb:5PRL|rcsb pdb:5PRM|rcsb pdb:5PRO|rcsb pdb:5PRP|rcsb pdb:5PRQ|rcsb pdb:5PRR|rcsb pdb:5PRS|rcsb pdb:5PRT|rcsb pdb:5PRU|rcsb pdb:5PRV|rcsb pdb:5PRW|rcsb pdb:5PRX|rcsb pdb:5PRY|rcsb pdb:5PRZ|rcsb pdb:5PS0|rcsb pdb:5PS1|rcsb pdb:5PS2|rcsb pdb:5PS3|rcsb pdb:5PS4|rcsb pdb:5PS5|rcsb pdb:5PS6|rcsb pdb:5PS7|rcsb pdb:5PS8|rcsb pdb:5PS9|rcsb pdb:5PSA|rcsb pdb:5PSB|rcsb pdb:5PSC|rcsb pdb:5PSD|rcsb pdb:5PSE|rcsb pdb:5PSF|rcsb pdb:5PSG|rcsb pdb:5PSH|rcsb pdb:5PSI|rcsb pdb:5PSJ|rcsb pdb:5PSK|rcsb pdb:5PSL|rcsb pdb:5PSM|rcsb pdb:5PSN|rcsb pdb:5PSO|rcsb pdb:5PSP|rcsb pdb:5PSQ|rcsb pdb:5PSR|rcsb pdb:5PSS|rcsb pdb:5PSU|rcsb pdb:5PSV|rcsb pdb:5PSW|rcsb pdb:5PSX|rcsb pdb:5PSY|rcsb pdb:5PSZ|rcsb pdb:5PT0|rcsb pdb:5PT1|rcsb pdb:5PT2|rcsb pdb:5PT3|rcsb pdb:5PT4|rcsb pdb:5PT5|rcsb pdb:5PT6|rcsb pdb:5PT7|rcsb pdb:5PT8|rcsb pdb:5PT9|rcsb pdb:5PTA|rcsb pdb:5PTB|rcsb pdb:5PTC|rcsb pdb:5PTE|rcsb pdb:5PTF|rcsb pdb:5PTG|rcsb pdb:5PTH|rcsb pdb:5PTJ|rcsb pdb:5PTK|rcsb pdb:5PTL|rcsb pdb:5PTM|rcsb pdb:5PTN|rcsb pdb:5PTO|rcsb pdb:5PTQ|rcsb pdb:5PTR|rcsb pdb:5PTS|rcsb pdb:5PTT|rcsb pdb:5PTU|rcsb pdb:5PTV|rcsb pdb:5PTW|rcsb pdb:5PTX|rcsb pdb:5PTY|rcsb pdb:5PTZ|rcsb pdb:5PU0|rcsb pdb:5PU1|rcsb pdb:5PU2|rcsb pdb:5PU3|rcsb pdb:5PU4|rcsb pdb:5PU5|rcsb pdb:5PU6|rcsb pdb:5PU7|rcsb pdb:5PU8|rcsb pdb:5PU9|rcsb pdb:5PUA|rcsb pdb:5PUB|rcsb pdb:5PUC|rcsb pdb:5PUD|rcsb pdb:5PUE|rcsb pdb:5PUF|rcsb pdb:5PUG|rcsb pdb:5PUH|rcsb pdb:5PUI|rcsb pdb:5PUJ|rcsb pdb:5PUK|rcsb pdb:5PUL|rcsb pdb:5PUM|rcsb pdb:5PUN|rcsb pdb:5PUO|rcsb pdb:5PUP|rcsb pdb:5PUQ|rcsb pdb:5PUR|rcsb pdb:5PUS|rcsb pdb:5PUT|rcsb pdb:5PUU|rcsb pdb:5PUV|rcsb pdb:5PUW|rcsb pdb:5PUX|rcsb pdb:5PUY|rcsb pdb:5PUZ|rcsb pdb:5PV0|rcsb pdb:5PV1|rcsb pdb:5PV2|rcsb pdb:5PV3|rcsb pdb:5PV4|rcsb pdb:5PV5|rcsb pdb:5PV6|rcsb pdb:5PV7|rcsb pdb:5PV8|rcsb pdb:5PV9|rcsb pdb:5PVA|rcsb pdb:5PVB|rcsb pdb:5PVC|rcsb pdb:5PVD|rcsb pdb:5PVE|rcsb pdb:5PVF|rcsb pdb:5PVG|rcsb pdb:5PVH|rcsb pdb:5PVI|rcsb pdb:5PVJ|rcsb pdb:5PVK|rcsb pdb:5PVL|rcsb pdb:5PVM|rcsb pdb:5PVN|rcsb pdb:5PVO|rcsb pdb:5PVP|rcsb pdb:5PVQ|rcsb pdb:5PVR|rcsb pdb:5PVS|rcsb pdb:5PVT|rcsb pdb:5PVU|rcsb pdb:5PVV|rcsb pdb:5PVW|rcsb pdb:5PVX|rcsb pdb:5PVY|rcsb pdb:5PVZ|rcsb pdb:5PW0|rcsb pdb:5PW1|rcsb pdb:5PW2|rcsb pdb:5PW3|rcsb pdb:5PW4|rcsb pdb:5PW5|rcsb pdb:5PW6|rcsb pdb:5PW7|rcsb pdb:5PW8|rcsb pdb:5PW9|rcsb pdb:5PWA|rcsb pdb:5PWB|rcsb pdb:6IN2|rcsb pdb:6MAJ|rcsb pdb:6MAK|rcsb pdb:7LH9|reactome:R-HSA-3214847|reactome:R-HSA-6804758|refseq:NP_001291737.1|refseq:NP_001291738.1|refseq:XP_016884204.1|refseq:XP_016884205.1 refseq:NP_005723.2|dip:DIP-33606N|ensembl:ENSG00000113522(gene)|ensembl:ENST00000378823(transcript)|go:"GO:0000019"(regulation of mitotic recombination)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:1904354"(negative regulation of telomere capping)|interpro:IPR013134(Zinc hook, Rad50)|interpro:IPR027417|interpro:IPR038729|mint:Q92878|rcsb pdb:5GOX|reactome:R-HSA-2559586|reactome:R-HSA-5685938|reactome:R-HSA-5685939|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446|interpro:IPR004584(Recombination/repair protein Rad50) - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:P/L2yjwT2CYr7rO64cYcdahm2z09606 rogid:yZsT5GcpA9HeFMoK4Jb1HYhrdKQ9606 rigid:61ptXJ352/6k7OWcQc+mQW/uIAg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95696 uniprotkb:Q5T2N8 intact:EBI-714754|uniprotkb:A6ZJA4|ensembl:ENSP00000216267|ensembl:ENSP00000384076 intact:EBI-2880061|ensembl:ENSP00000368062|uniprotkb:Q8N1Z5 psi-mi:brd1_human(display_long)|uniprotkb:BR140-like protein(gene name synonym)|uniprotkb:BRD1(gene name)|psi-mi:BRD1(display_short)|uniprotkb:BRL(gene name synonym)|uniprotkb:BRPF2(gene name synonym)|uniprotkb:Bromodomain and PHD finger-containing protein 2(gene name synonym) psi-mi:atd3c_human(display_long)|uniprotkb:ATAD3C(gene name)|psi-mi:ATAD3C(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476670|imex:IM-26985-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0036409"(histone H3-K14 acetyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051602"(response to electrical stimulus)|ensembl:ENSG00000100425(gene)|ensembl:ENST00000216267(transcript)|ensembl:ENST00000404034(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0016607"(nuclear speck)|go:"GO:0030425"(dendrite)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042004|interpro:IPR042009|mint:O95696|rcsb pdb:2KU3|rcsb pdb:2L43|rcsb pdb:2LQ6|rcsb pdb:3LYI|rcsb pdb:3RCW|rcsb pdb:4Z02|rcsb pdb:5AME|rcsb pdb:5AMF|rcsb pdb:5FG6|rcsb pdb:5GK9|rcsb pdb:5N49|rcsb pdb:5PNX|rcsb pdb:5PNY|rcsb pdb:5PNZ|rcsb pdb:5PO0|rcsb pdb:5PO1|rcsb pdb:5PO2|rcsb pdb:5PO3|rcsb pdb:5PO4|rcsb pdb:5PO5|rcsb pdb:5PO6|rcsb pdb:5PO7|rcsb pdb:5PO8|rcsb pdb:5PO9|rcsb pdb:5POA|rcsb pdb:5POB|rcsb pdb:5POC|rcsb pdb:5POD|rcsb pdb:5POE|rcsb pdb:5POF|rcsb pdb:5POG|rcsb pdb:5POH|rcsb pdb:5POI|rcsb pdb:5POJ|rcsb pdb:5POK|rcsb pdb:5POL|rcsb pdb:5POM|rcsb pdb:5PON|rcsb pdb:5POO|rcsb pdb:5POP|rcsb pdb:5POQ|refseq:XP_016884206.1|rcsb pdb:5POR|rcsb pdb:5POS|rcsb pdb:5POT|rcsb pdb:5POU|rcsb pdb:5POV|rcsb pdb:5POW|rcsb pdb:5POX|rcsb pdb:5POY|rcsb pdb:5POZ|rcsb pdb:5PP0|rcsb pdb:5PP1|rcsb pdb:5PP2|rcsb pdb:5PP3|rcsb pdb:5PP4|rcsb pdb:5PP5|rcsb pdb:5PP6|rcsb pdb:5PP7|rcsb pdb:5PP8|rcsb pdb:5PP9|rcsb pdb:5PPA|rcsb pdb:5PPB|rcsb pdb:5PPC|rcsb pdb:5PPD|rcsb pdb:5PPE|rcsb pdb:5PPF|rcsb pdb:5PPG|rcsb pdb:5PPH|rcsb pdb:5PPI|rcsb pdb:5PPJ|rcsb pdb:5PPK|rcsb pdb:5PPL|rcsb pdb:5PPM|rcsb pdb:5PPN|rcsb pdb:5PPO|rcsb pdb:5PPP|rcsb pdb:5PPQ|rcsb pdb:5PPR|rcsb pdb:5PPS|rcsb pdb:5PPT|rcsb pdb:5PPU|rcsb pdb:5PPV|rcsb pdb:5PPW|rcsb pdb:5PPX|rcsb pdb:5PPY|rcsb pdb:5PPZ|rcsb pdb:5PQ0|rcsb pdb:5PQ1|rcsb pdb:5PQ2|rcsb pdb:5PQ3|rcsb pdb:5PQ4|rcsb pdb:5PQ5|rcsb pdb:5PQ6|rcsb pdb:5PQ7|rcsb pdb:5PQ8|rcsb pdb:5PQ9|rcsb pdb:5PQA|rcsb pdb:5PQB|rcsb pdb:5PQC|rcsb pdb:5PQD|rcsb pdb:5PQE|rcsb pdb:5PQF|rcsb pdb:5PQG|rcsb pdb:5PQH|rcsb pdb:5PQI|rcsb pdb:5PQJ|rcsb pdb:5PQK|rcsb pdb:5PQL|rcsb pdb:5PQM|rcsb pdb:5PQN|rcsb pdb:5PQO|rcsb pdb:5PQP|rcsb pdb:5PQQ|rcsb pdb:5PQR|rcsb pdb:5PQS|rcsb pdb:5PQT|rcsb pdb:5PQU|rcsb pdb:5PQV|rcsb pdb:5PQW|rcsb pdb:5PQX|rcsb pdb:5PQY|rcsb pdb:5PQZ|rcsb pdb:5PR0|rcsb pdb:5PR1|rcsb pdb:5PR2|rcsb pdb:5PR4|rcsb pdb:5PR5|rcsb pdb:5PR6|rcsb pdb:5PR7|rcsb pdb:5PR8|rcsb pdb:5PST|rcsb pdb:5PR9|rcsb pdb:5PRA|rcsb pdb:5PRB|rcsb pdb:5PRD|rcsb pdb:5PRE|rcsb pdb:5PRF|rcsb pdb:5PRG|rcsb pdb:5PRH|rcsb pdb:5PRI|rcsb pdb:5PRJ|rcsb pdb:5PRK|rcsb pdb:5PRL|rcsb pdb:5PRM|rcsb pdb:5PRO|rcsb pdb:5PRP|rcsb pdb:5PRQ|rcsb pdb:5PRR|rcsb pdb:5PRS|rcsb pdb:5PRT|rcsb pdb:5PRU|rcsb pdb:5PRV|rcsb pdb:5PRW|rcsb pdb:5PRX|rcsb pdb:5PRY|rcsb pdb:5PRZ|rcsb pdb:5PS0|rcsb pdb:5PS1|rcsb pdb:5PS2|rcsb pdb:5PS3|rcsb pdb:5PS4|rcsb pdb:5PS5|rcsb pdb:5PS6|rcsb pdb:5PS7|rcsb pdb:5PS8|rcsb pdb:5PS9|rcsb pdb:5PSA|rcsb pdb:5PSB|rcsb pdb:5PSC|rcsb pdb:5PSD|rcsb pdb:5PSE|rcsb pdb:5PSF|rcsb pdb:5PSG|rcsb pdb:5PSH|rcsb pdb:5PSI|rcsb pdb:5PSJ|rcsb pdb:5PSK|rcsb pdb:5PSL|rcsb pdb:5PSM|rcsb pdb:5PSN|rcsb pdb:5PSO|rcsb pdb:5PSP|rcsb pdb:5PSQ|rcsb pdb:5PSR|rcsb pdb:5PSS|rcsb pdb:5PSU|rcsb pdb:5PSV|rcsb pdb:5PSW|rcsb pdb:5PSX|rcsb pdb:5PSY|rcsb pdb:5PSZ|rcsb pdb:5PT0|rcsb pdb:5PT1|rcsb pdb:5PT2|rcsb pdb:5PT3|rcsb pdb:5PT4|rcsb pdb:5PT5|rcsb pdb:5PT6|rcsb pdb:5PT7|rcsb pdb:5PT8|rcsb pdb:5PT9|rcsb pdb:5PTA|rcsb pdb:5PTB|rcsb pdb:5PTC|rcsb pdb:5PTE|rcsb pdb:5PTF|rcsb pdb:5PTG|rcsb pdb:5PTH|rcsb pdb:5PTJ|rcsb pdb:5PTK|rcsb pdb:5PTL|rcsb pdb:5PTM|rcsb pdb:5PTN|rcsb pdb:5PTO|rcsb pdb:5PTQ|rcsb pdb:5PTR|rcsb pdb:5PTS|rcsb pdb:5PTT|rcsb pdb:5PTU|rcsb pdb:5PTV|rcsb pdb:5PTW|rcsb pdb:5PTX|rcsb pdb:5PTY|rcsb pdb:5PTZ|rcsb pdb:5PU0|rcsb pdb:5PU1|rcsb pdb:5PU2|rcsb pdb:5PU3|rcsb pdb:5PU4|rcsb pdb:5PU5|rcsb pdb:5PU6|rcsb pdb:5PU7|rcsb pdb:5PU8|rcsb pdb:5PU9|rcsb pdb:5PUA|rcsb pdb:5PUB|rcsb pdb:5PUC|rcsb pdb:5PUD|rcsb pdb:5PUE|rcsb pdb:5PUF|rcsb pdb:5PUG|rcsb pdb:5PUH|rcsb pdb:5PUI|rcsb pdb:5PUJ|rcsb pdb:5PUK|rcsb pdb:5PUL|rcsb pdb:5PUM|rcsb pdb:5PUN|rcsb pdb:5PUO|rcsb pdb:5PUP|rcsb pdb:5PUQ|rcsb pdb:5PUR|rcsb pdb:5PUS|rcsb pdb:5PUT|rcsb pdb:5PUU|rcsb pdb:5PUV|rcsb pdb:5PUW|rcsb pdb:5PUX|rcsb pdb:5PUY|rcsb pdb:5PUZ|rcsb pdb:5PV0|rcsb pdb:5PV1|rcsb pdb:5PV2|rcsb pdb:5PV3|rcsb pdb:5PV4|rcsb pdb:5PV5|rcsb pdb:5PV6|rcsb pdb:5PV7|rcsb pdb:5PV8|rcsb pdb:5PV9|rcsb pdb:5PVA|rcsb pdb:5PVB|rcsb pdb:5PVC|rcsb pdb:5PVD|rcsb pdb:5PVE|rcsb pdb:5PVF|rcsb pdb:5PVG|rcsb pdb:5PVH|rcsb pdb:5PVI|rcsb pdb:5PVJ|rcsb pdb:5PVK|rcsb pdb:5PVL|rcsb pdb:5PVM|rcsb pdb:5PVN|rcsb pdb:5PVO|rcsb pdb:5PVP|rcsb pdb:5PVQ|rcsb pdb:5PVR|rcsb pdb:5PVS|rcsb pdb:5PVT|rcsb pdb:5PVU|rcsb pdb:5PVV|rcsb pdb:5PVW|rcsb pdb:5PVX|rcsb pdb:5PVY|rcsb pdb:5PVZ|rcsb pdb:5PW0|rcsb pdb:5PW1|rcsb pdb:5PW2|rcsb pdb:5PW3|rcsb pdb:5PW4|rcsb pdb:5PW5|rcsb pdb:5PW6|rcsb pdb:5PW7|rcsb pdb:5PW8|rcsb pdb:5PW9|rcsb pdb:5PWA|rcsb pdb:5PWB|rcsb pdb:6IN2|rcsb pdb:6MAJ|rcsb pdb:6MAK|rcsb pdb:7LH9|reactome:R-HSA-3214847|reactome:R-HSA-6804758|refseq:NP_001291737.1|refseq:NP_001291738.1|refseq:XP_016884204.1|refseq:XP_016884205.1 ensembl:ENSG00000215915(gene)|ensembl:ENST00000378785(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008270"(zinc ion binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR021911|interpro:IPR027417|interpro:IPR039188|mint:Q5T2N8|refseq:NP_001034300.2 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:P/L2yjwT2CYr7rO64cYcdahm2z09606 rogid:JP1/f7Mg8jNYnXeYRsoIxhk6t+s9606 rigid:61ptXJ352/6k7OWcQc+mQW/uIAg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95696 uniprotkb:P62258 intact:EBI-714754|uniprotkb:A6ZJA4|ensembl:ENSP00000216267|ensembl:ENSP00000384076 intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335|ensembl:ENSP00000487356 psi-mi:brd1_human(display_long)|uniprotkb:BR140-like protein(gene name synonym)|uniprotkb:BRD1(gene name)|psi-mi:BRD1(display_short)|uniprotkb:BRL(gene name synonym)|uniprotkb:BRPF2(gene name synonym)|uniprotkb:Bromodomain and PHD finger-containing protein 2(gene name synonym) psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476670|imex:IM-26985-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0036409"(histone H3-K14 acetyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051602"(response to electrical stimulus)|ensembl:ENSG00000100425(gene)|ensembl:ENST00000216267(transcript)|ensembl:ENST00000404034(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0016607"(nuclear speck)|go:"GO:0030425"(dendrite)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042004|interpro:IPR042009|mint:O95696|rcsb pdb:2KU3|rcsb pdb:2L43|rcsb pdb:2LQ6|rcsb pdb:3LYI|rcsb pdb:3RCW|rcsb pdb:4Z02|rcsb pdb:5AME|rcsb pdb:5AMF|rcsb pdb:5FG6|rcsb pdb:5GK9|rcsb pdb:5N49|rcsb pdb:5PNX|rcsb pdb:5PNY|rcsb pdb:5PNZ|rcsb pdb:5PO0|rcsb pdb:5PO1|rcsb pdb:5PO2|rcsb pdb:5PO3|rcsb pdb:5PO4|rcsb pdb:5PO5|rcsb pdb:5PO6|rcsb pdb:5PO7|rcsb pdb:5PO8|rcsb pdb:5PO9|rcsb pdb:5POA|rcsb pdb:5POB|rcsb pdb:5POC|rcsb pdb:5POD|rcsb pdb:5POE|rcsb pdb:5POF|rcsb pdb:5POG|rcsb pdb:5POH|rcsb pdb:5POI|rcsb pdb:5POJ|rcsb pdb:5POK|rcsb pdb:5POL|rcsb pdb:5POM|rcsb pdb:5PON|rcsb pdb:5POO|rcsb pdb:5POP|rcsb pdb:5POQ|refseq:XP_016884206.1|rcsb pdb:5POR|rcsb pdb:5POS|rcsb pdb:5POT|rcsb pdb:5POU|rcsb pdb:5POV|rcsb pdb:5POW|rcsb pdb:5POX|rcsb pdb:5POY|rcsb pdb:5POZ|rcsb pdb:5PP0|rcsb pdb:5PP1|rcsb pdb:5PP2|rcsb pdb:5PP3|rcsb pdb:5PP4|rcsb pdb:5PP5|rcsb pdb:5PP6|rcsb pdb:5PP7|rcsb pdb:5PP8|rcsb pdb:5PP9|rcsb pdb:5PPA|rcsb pdb:5PPB|rcsb pdb:5PPC|rcsb pdb:5PPD|rcsb pdb:5PPE|rcsb pdb:5PPF|rcsb pdb:5PPG|rcsb pdb:5PPH|rcsb pdb:5PPI|rcsb pdb:5PPJ|rcsb pdb:5PPK|rcsb pdb:5PPL|rcsb pdb:5PPM|rcsb pdb:5PPN|rcsb pdb:5PPO|rcsb pdb:5PPP|rcsb pdb:5PPQ|rcsb pdb:5PPR|rcsb pdb:5PPS|rcsb pdb:5PPT|rcsb pdb:5PPU|rcsb pdb:5PPV|rcsb pdb:5PPW|rcsb pdb:5PPX|rcsb pdb:5PPY|rcsb pdb:5PPZ|rcsb pdb:5PQ0|rcsb pdb:5PQ1|rcsb pdb:5PQ2|rcsb pdb:5PQ3|rcsb pdb:5PQ4|rcsb pdb:5PQ5|rcsb pdb:5PQ6|rcsb pdb:5PQ7|rcsb pdb:5PQ8|rcsb pdb:5PQ9|rcsb pdb:5PQA|rcsb pdb:5PQB|rcsb pdb:5PQC|rcsb pdb:5PQD|rcsb pdb:5PQE|rcsb pdb:5PQF|rcsb pdb:5PQG|rcsb pdb:5PQH|rcsb pdb:5PQI|rcsb pdb:5PQJ|rcsb pdb:5PQK|rcsb pdb:5PQL|rcsb pdb:5PQM|rcsb pdb:5PQN|rcsb pdb:5PQO|rcsb pdb:5PQP|rcsb pdb:5PQQ|rcsb pdb:5PQR|rcsb pdb:5PQS|rcsb pdb:5PQT|rcsb pdb:5PQU|rcsb pdb:5PQV|rcsb pdb:5PQW|rcsb pdb:5PQX|rcsb pdb:5PQY|rcsb pdb:5PQZ|rcsb pdb:5PR0|rcsb pdb:5PR1|rcsb pdb:5PR2|rcsb pdb:5PR4|rcsb pdb:5PR5|rcsb pdb:5PR6|rcsb pdb:5PR7|rcsb pdb:5PR8|rcsb pdb:5PST|rcsb pdb:5PR9|rcsb pdb:5PRA|rcsb pdb:5PRB|rcsb pdb:5PRD|rcsb pdb:5PRE|rcsb pdb:5PRF|rcsb pdb:5PRG|rcsb pdb:5PRH|rcsb pdb:5PRI|rcsb pdb:5PRJ|rcsb pdb:5PRK|rcsb pdb:5PRL|rcsb pdb:5PRM|rcsb pdb:5PRO|rcsb pdb:5PRP|rcsb pdb:5PRQ|rcsb pdb:5PRR|rcsb pdb:5PRS|rcsb pdb:5PRT|rcsb pdb:5PRU|rcsb pdb:5PRV|rcsb pdb:5PRW|rcsb pdb:5PRX|rcsb pdb:5PRY|rcsb pdb:5PRZ|rcsb pdb:5PS0|rcsb pdb:5PS1|rcsb pdb:5PS2|rcsb pdb:5PS3|rcsb pdb:5PS4|rcsb pdb:5PS5|rcsb pdb:5PS6|rcsb pdb:5PS7|rcsb pdb:5PS8|rcsb pdb:5PS9|rcsb pdb:5PSA|rcsb pdb:5PSB|rcsb pdb:5PSC|rcsb pdb:5PSD|rcsb pdb:5PSE|rcsb pdb:5PSF|rcsb pdb:5PSG|rcsb pdb:5PSH|rcsb pdb:5PSI|rcsb pdb:5PSJ|rcsb pdb:5PSK|rcsb pdb:5PSL|rcsb pdb:5PSM|rcsb pdb:5PSN|rcsb pdb:5PSO|rcsb pdb:5PSP|rcsb pdb:5PSQ|rcsb pdb:5PSR|rcsb pdb:5PSS|rcsb pdb:5PSU|rcsb pdb:5PSV|rcsb pdb:5PSW|rcsb pdb:5PSX|rcsb pdb:5PSY|rcsb pdb:5PSZ|rcsb pdb:5PT0|rcsb pdb:5PT1|rcsb pdb:5PT2|rcsb pdb:5PT3|rcsb pdb:5PT4|rcsb pdb:5PT5|rcsb pdb:5PT6|rcsb pdb:5PT7|rcsb pdb:5PT8|rcsb pdb:5PT9|rcsb pdb:5PTA|rcsb pdb:5PTB|rcsb pdb:5PTC|rcsb pdb:5PTE|rcsb pdb:5PTF|rcsb pdb:5PTG|rcsb pdb:5PTH|rcsb pdb:5PTJ|rcsb pdb:5PTK|rcsb pdb:5PTL|rcsb pdb:5PTM|rcsb pdb:5PTN|rcsb pdb:5PTO|rcsb pdb:5PTQ|rcsb pdb:5PTR|rcsb pdb:5PTS|rcsb pdb:5PTT|rcsb pdb:5PTU|rcsb pdb:5PTV|rcsb pdb:5PTW|rcsb pdb:5PTX|rcsb pdb:5PTY|rcsb pdb:5PTZ|rcsb pdb:5PU0|rcsb pdb:5PU1|rcsb pdb:5PU2|rcsb pdb:5PU3|rcsb pdb:5PU4|rcsb pdb:5PU5|rcsb pdb:5PU6|rcsb pdb:5PU7|rcsb pdb:5PU8|rcsb pdb:5PU9|rcsb pdb:5PUA|rcsb pdb:5PUB|rcsb pdb:5PUC|rcsb pdb:5PUD|rcsb pdb:5PUE|rcsb pdb:5PUF|rcsb pdb:5PUG|rcsb pdb:5PUH|rcsb pdb:5PUI|rcsb pdb:5PUJ|rcsb pdb:5PUK|rcsb pdb:5PUL|rcsb pdb:5PUM|rcsb pdb:5PUN|rcsb pdb:5PUO|rcsb pdb:5PUP|rcsb pdb:5PUQ|rcsb pdb:5PUR|rcsb pdb:5PUS|rcsb pdb:5PUT|rcsb pdb:5PUU|rcsb pdb:5PUV|rcsb pdb:5PUW|rcsb pdb:5PUX|rcsb pdb:5PUY|rcsb pdb:5PUZ|rcsb pdb:5PV0|rcsb pdb:5PV1|rcsb pdb:5PV2|rcsb pdb:5PV3|rcsb pdb:5PV4|rcsb pdb:5PV5|rcsb pdb:5PV6|rcsb pdb:5PV7|rcsb pdb:5PV8|rcsb pdb:5PV9|rcsb pdb:5PVA|rcsb pdb:5PVB|rcsb pdb:5PVC|rcsb pdb:5PVD|rcsb pdb:5PVE|rcsb pdb:5PVF|rcsb pdb:5PVG|rcsb pdb:5PVH|rcsb pdb:5PVI|rcsb pdb:5PVJ|rcsb pdb:5PVK|rcsb pdb:5PVL|rcsb pdb:5PVM|rcsb pdb:5PVN|rcsb pdb:5PVO|rcsb pdb:5PVP|rcsb pdb:5PVQ|rcsb pdb:5PVR|rcsb pdb:5PVS|rcsb pdb:5PVT|rcsb pdb:5PVU|rcsb pdb:5PVV|rcsb pdb:5PVW|rcsb pdb:5PVX|rcsb pdb:5PVY|rcsb pdb:5PVZ|rcsb pdb:5PW0|rcsb pdb:5PW1|rcsb pdb:5PW2|rcsb pdb:5PW3|rcsb pdb:5PW4|rcsb pdb:5PW5|rcsb pdb:5PW6|rcsb pdb:5PW7|rcsb pdb:5PW8|rcsb pdb:5PW9|rcsb pdb:5PWA|rcsb pdb:5PWB|rcsb pdb:6IN2|rcsb pdb:6MAJ|rcsb pdb:6MAK|rcsb pdb:7LH9|reactome:R-HSA-3214847|reactome:R-HSA-6804758|refseq:NP_001291737.1|refseq:NP_001291738.1|refseq:XP_016884204.1|refseq:XP_016884205.1 refseq:NP_006752.1|dip:DIP-36676N|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|ensembl:ENSG00000108953(gene)|ensembl:ENSG00000274474(gene)|ensembl:ENST00000264335(transcript)|ensembl:ENST00000627231(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003064"(regulation of heart rate by hormone)|go:"GO:0003723"(RNA binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|reactome:R-HSA-111447 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:P/L2yjwT2CYr7rO64cYcdahm2z09606 rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606 rigid:61ptXJ352/6k7OWcQc+mQW/uIAg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95696 uniprotkb:P53041 intact:EBI-714754|uniprotkb:A6ZJA4|ensembl:ENSP00000216267|ensembl:ENSP00000384076 intact:EBI-716663|uniprotkb:Q53XV2|uniprotkb:Q16722|ensembl:ENSP00000012443 psi-mi:brd1_human(display_long)|uniprotkb:BR140-like protein(gene name synonym)|uniprotkb:BRD1(gene name)|psi-mi:BRD1(display_short)|uniprotkb:BRL(gene name synonym)|uniprotkb:BRPF2(gene name synonym)|uniprotkb:Bromodomain and PHD finger-containing protein 2(gene name synonym) psi-mi:ppp5_human(display_long)|uniprotkb:Protein phosphatase T(gene name synonym)|uniprotkb:PPP5C(gene name)|psi-mi:PPP5C(display_short)|uniprotkb:PPP5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476670|imex:IM-26985-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0036409"(histone H3-K14 acetyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051602"(response to electrical stimulus)|ensembl:ENSG00000100425(gene)|ensembl:ENST00000216267(transcript)|ensembl:ENST00000404034(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0016607"(nuclear speck)|go:"GO:0030425"(dendrite)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042004|interpro:IPR042009|mint:O95696|rcsb pdb:2KU3|rcsb pdb:2L43|rcsb pdb:2LQ6|rcsb pdb:3LYI|rcsb pdb:3RCW|rcsb pdb:4Z02|rcsb pdb:5AME|rcsb pdb:5AMF|rcsb pdb:5FG6|rcsb pdb:5GK9|rcsb pdb:5N49|rcsb pdb:5PNX|rcsb pdb:5PNY|rcsb pdb:5PNZ|rcsb pdb:5PO0|rcsb pdb:5PO1|rcsb pdb:5PO2|rcsb pdb:5PO3|rcsb pdb:5PO4|rcsb pdb:5PO5|rcsb pdb:5PO6|rcsb pdb:5PO7|rcsb pdb:5PO8|rcsb pdb:5PO9|rcsb pdb:5POA|rcsb pdb:5POB|rcsb pdb:5POC|rcsb pdb:5POD|rcsb pdb:5POE|rcsb pdb:5POF|rcsb pdb:5POG|rcsb pdb:5POH|rcsb pdb:5POI|rcsb pdb:5POJ|rcsb pdb:5POK|rcsb pdb:5POL|rcsb pdb:5POM|rcsb pdb:5PON|rcsb pdb:5POO|rcsb pdb:5POP|rcsb pdb:5POQ|refseq:XP_016884206.1|rcsb pdb:5POR|rcsb pdb:5POS|rcsb pdb:5POT|rcsb pdb:5POU|rcsb pdb:5POV|rcsb pdb:5POW|rcsb pdb:5POX|rcsb pdb:5POY|rcsb pdb:5POZ|rcsb pdb:5PP0|rcsb pdb:5PP1|rcsb pdb:5PP2|rcsb pdb:5PP3|rcsb pdb:5PP4|rcsb pdb:5PP5|rcsb pdb:5PP6|rcsb pdb:5PP7|rcsb pdb:5PP8|rcsb pdb:5PP9|rcsb pdb:5PPA|rcsb pdb:5PPB|rcsb pdb:5PPC|rcsb pdb:5PPD|rcsb pdb:5PPE|rcsb pdb:5PPF|rcsb pdb:5PPG|rcsb pdb:5PPH|rcsb pdb:5PPI|rcsb pdb:5PPJ|rcsb pdb:5PPK|rcsb pdb:5PPL|rcsb pdb:5PPM|rcsb pdb:5PPN|rcsb pdb:5PPO|rcsb pdb:5PPP|rcsb pdb:5PPQ|rcsb pdb:5PPR|rcsb pdb:5PPS|rcsb pdb:5PPT|rcsb pdb:5PPU|rcsb pdb:5PPV|rcsb pdb:5PPW|rcsb pdb:5PPX|rcsb pdb:5PPY|rcsb pdb:5PPZ|rcsb pdb:5PQ0|rcsb pdb:5PQ1|rcsb pdb:5PQ2|rcsb pdb:5PQ3|rcsb pdb:5PQ4|rcsb pdb:5PQ5|rcsb pdb:5PQ6|rcsb pdb:5PQ7|rcsb pdb:5PQ8|rcsb pdb:5PQ9|rcsb pdb:5PQA|rcsb pdb:5PQB|rcsb pdb:5PQC|rcsb pdb:5PQD|rcsb pdb:5PQE|rcsb pdb:5PQF|rcsb pdb:5PQG|rcsb pdb:5PQH|rcsb pdb:5PQI|rcsb pdb:5PQJ|rcsb pdb:5PQK|rcsb pdb:5PQL|rcsb pdb:5PQM|rcsb pdb:5PQN|rcsb pdb:5PQO|rcsb pdb:5PQP|rcsb pdb:5PQQ|rcsb pdb:5PQR|rcsb pdb:5PQS|rcsb pdb:5PQT|rcsb pdb:5PQU|rcsb pdb:5PQV|rcsb pdb:5PQW|rcsb pdb:5PQX|rcsb pdb:5PQY|rcsb pdb:5PQZ|rcsb pdb:5PR0|rcsb pdb:5PR1|rcsb pdb:5PR2|rcsb pdb:5PR4|rcsb pdb:5PR5|rcsb pdb:5PR6|rcsb pdb:5PR7|rcsb pdb:5PR8|rcsb pdb:5PST|rcsb pdb:5PR9|rcsb pdb:5PRA|rcsb pdb:5PRB|rcsb pdb:5PRD|rcsb pdb:5PRE|rcsb pdb:5PRF|rcsb pdb:5PRG|rcsb pdb:5PRH|rcsb pdb:5PRI|rcsb pdb:5PRJ|rcsb pdb:5PRK|rcsb pdb:5PRL|rcsb pdb:5PRM|rcsb pdb:5PRO|rcsb pdb:5PRP|rcsb pdb:5PRQ|rcsb pdb:5PRR|rcsb pdb:5PRS|rcsb pdb:5PRT|rcsb pdb:5PRU|rcsb pdb:5PRV|rcsb pdb:5PRW|rcsb pdb:5PRX|rcsb pdb:5PRY|rcsb pdb:5PRZ|rcsb pdb:5PS0|rcsb pdb:5PS1|rcsb pdb:5PS2|rcsb pdb:5PS3|rcsb pdb:5PS4|rcsb pdb:5PS5|rcsb pdb:5PS6|rcsb pdb:5PS7|rcsb pdb:5PS8|rcsb pdb:5PS9|rcsb pdb:5PSA|rcsb pdb:5PSB|rcsb pdb:5PSC|rcsb pdb:5PSD|rcsb pdb:5PSE|rcsb pdb:5PSF|rcsb pdb:5PSG|rcsb pdb:5PSH|rcsb pdb:5PSI|rcsb pdb:5PSJ|rcsb pdb:5PSK|rcsb pdb:5PSL|rcsb pdb:5PSM|rcsb pdb:5PSN|rcsb pdb:5PSO|rcsb pdb:5PSP|rcsb pdb:5PSQ|rcsb pdb:5PSR|rcsb pdb:5PSS|rcsb pdb:5PSU|rcsb pdb:5PSV|rcsb pdb:5PSW|rcsb pdb:5PSX|rcsb pdb:5PSY|rcsb pdb:5PSZ|rcsb pdb:5PT0|rcsb pdb:5PT1|rcsb pdb:5PT2|rcsb pdb:5PT3|rcsb pdb:5PT4|rcsb pdb:5PT5|rcsb pdb:5PT6|rcsb pdb:5PT7|rcsb pdb:5PT8|rcsb pdb:5PT9|rcsb pdb:5PTA|rcsb pdb:5PTB|rcsb pdb:5PTC|rcsb pdb:5PTE|rcsb pdb:5PTF|rcsb pdb:5PTG|rcsb pdb:5PTH|rcsb pdb:5PTJ|rcsb pdb:5PTK|rcsb pdb:5PTL|rcsb pdb:5PTM|rcsb pdb:5PTN|rcsb pdb:5PTO|rcsb pdb:5PTQ|rcsb pdb:5PTR|rcsb pdb:5PTS|rcsb pdb:5PTT|rcsb pdb:5PTU|rcsb pdb:5PTV|rcsb pdb:5PTW|rcsb pdb:5PTX|rcsb pdb:5PTY|rcsb pdb:5PTZ|rcsb pdb:5PU0|rcsb pdb:5PU1|rcsb pdb:5PU2|rcsb pdb:5PU3|rcsb pdb:5PU4|rcsb pdb:5PU5|rcsb pdb:5PU6|rcsb pdb:5PU7|rcsb pdb:5PU8|rcsb pdb:5PU9|rcsb pdb:5PUA|rcsb pdb:5PUB|rcsb pdb:5PUC|rcsb pdb:5PUD|rcsb pdb:5PUE|rcsb pdb:5PUF|rcsb pdb:5PUG|rcsb pdb:5PUH|rcsb pdb:5PUI|rcsb pdb:5PUJ|rcsb pdb:5PUK|rcsb pdb:5PUL|rcsb pdb:5PUM|rcsb pdb:5PUN|rcsb pdb:5PUO|rcsb pdb:5PUP|rcsb pdb:5PUQ|rcsb pdb:5PUR|rcsb pdb:5PUS|rcsb pdb:5PUT|rcsb pdb:5PUU|rcsb pdb:5PUV|rcsb pdb:5PUW|rcsb pdb:5PUX|rcsb pdb:5PUY|rcsb pdb:5PUZ|rcsb pdb:5PV0|rcsb pdb:5PV1|rcsb pdb:5PV2|rcsb pdb:5PV3|rcsb pdb:5PV4|rcsb pdb:5PV5|rcsb pdb:5PV6|rcsb pdb:5PV7|rcsb pdb:5PV8|rcsb pdb:5PV9|rcsb pdb:5PVA|rcsb pdb:5PVB|rcsb pdb:5PVC|rcsb pdb:5PVD|rcsb pdb:5PVE|rcsb pdb:5PVF|rcsb pdb:5PVG|rcsb pdb:5PVH|rcsb pdb:5PVI|rcsb pdb:5PVJ|rcsb pdb:5PVK|rcsb pdb:5PVL|rcsb pdb:5PVM|rcsb pdb:5PVN|rcsb pdb:5PVO|rcsb pdb:5PVP|rcsb pdb:5PVQ|rcsb pdb:5PVR|rcsb pdb:5PVS|rcsb pdb:5PVT|rcsb pdb:5PVU|rcsb pdb:5PVV|rcsb pdb:5PVW|rcsb pdb:5PVX|rcsb pdb:5PVY|rcsb pdb:5PVZ|rcsb pdb:5PW0|rcsb pdb:5PW1|rcsb pdb:5PW2|rcsb pdb:5PW3|rcsb pdb:5PW4|rcsb pdb:5PW5|rcsb pdb:5PW6|rcsb pdb:5PW7|rcsb pdb:5PW8|rcsb pdb:5PW9|rcsb pdb:5PWA|rcsb pdb:5PWB|rcsb pdb:6IN2|rcsb pdb:6MAJ|rcsb pdb:6MAK|rcsb pdb:7LH9|reactome:R-HSA-3214847|reactome:R-HSA-6804758|refseq:NP_001291737.1|refseq:NP_001291738.1|refseq:XP_016884204.1|refseq:XP_016884205.1 refseq:NP_006238.1|ensembl:ENSG00000011485(gene)|ensembl:ENST00000012443(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008017"(microtubule binding)|go:"GO:0008289"(lipid binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0016576"(histone dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043204"(perikaryon)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043278"(response to morphine)|go:"GO:0043531"(ADP binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0101031"(chaperone complex)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1904550"(response to arachidonic acid)|go:"GO:1990635"(proximal dendrite)|go:"GO:2000324"(positive regulation of glucocorticoid receptor signaling pathway)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR011236(Protein phosphatase 5)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013235(Serine/threonine phosphatase, PPP5)|interpro:IPR019734|interpro:IPR029052|interpro:IPR041753|mint:P53041|rcsb pdb:1A17|rcsb pdb:1S95|rcsb pdb:1WAO|rcsb pdb:2BUG|rcsb pdb:3H60|rcsb pdb:3H61|rcsb pdb:3H62|rcsb pdb:3H63|rcsb pdb:3H64|rcsb pdb:3H66|rcsb pdb:3H67|rcsb pdb:3H68|rcsb pdb:3H69|rcsb pdb:4ZVZ|rcsb pdb:4ZX2|rcsb pdb:5HPE|rcsb pdb:5UI1|rcsb pdb:5WG8|reactome:R-HSA-5675221|reactome:R-HSA-5693565|reactome:R-HSA-8939211|dip:DIP-29043N - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:P/L2yjwT2CYr7rO64cYcdahm2z09606 rogid:5QoNB467ftOvWaUNfSm6RalR8+Y9606 rigid:61ptXJ352/6k7OWcQc+mQW/uIAg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95696 uniprotkb:Q9NWU2 intact:EBI-714754|uniprotkb:A6ZJA4|ensembl:ENSP00000216267|ensembl:ENSP00000384076 intact:EBI-1051077|uniprotkb:Q8N5M5|uniprotkb:E1P5I3|ensembl:ENSP00000266069 psi-mi:brd1_human(display_long)|uniprotkb:BR140-like protein(gene name synonym)|uniprotkb:BRD1(gene name)|psi-mi:BRD1(display_short)|uniprotkb:BRL(gene name synonym)|uniprotkb:BRPF2(gene name synonym)|uniprotkb:Bromodomain and PHD finger-containing protein 2(gene name synonym) psi-mi:gid8_human(display_long)|uniprotkb:GID8(gene name)|psi-mi:GID8(display_short)|uniprotkb:C20orf11(gene name synonym)|uniprotkb:Two hybrid-associated protein 1 with RanBPM(gene name synonym)|uniprotkb:TWA1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476670|imex:IM-26985-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0036409"(histone H3-K14 acetyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051602"(response to electrical stimulus)|ensembl:ENSG00000100425(gene)|ensembl:ENST00000216267(transcript)|ensembl:ENST00000404034(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0016607"(nuclear speck)|go:"GO:0030425"(dendrite)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042004|interpro:IPR042009|mint:O95696|rcsb pdb:2KU3|rcsb pdb:2L43|rcsb pdb:2LQ6|rcsb pdb:3LYI|rcsb pdb:3RCW|rcsb pdb:4Z02|rcsb pdb:5AME|rcsb pdb:5AMF|rcsb pdb:5FG6|rcsb pdb:5GK9|rcsb pdb:5N49|rcsb pdb:5PNX|rcsb pdb:5PNY|rcsb pdb:5PNZ|rcsb pdb:5PO0|rcsb pdb:5PO1|rcsb pdb:5PO2|rcsb pdb:5PO3|rcsb pdb:5PO4|rcsb pdb:5PO5|rcsb pdb:5PO6|rcsb pdb:5PO7|rcsb pdb:5PO8|rcsb pdb:5PO9|rcsb pdb:5POA|rcsb pdb:5POB|rcsb pdb:5POC|rcsb pdb:5POD|rcsb pdb:5POE|rcsb pdb:5POF|rcsb pdb:5POG|rcsb pdb:5POH|rcsb pdb:5POI|rcsb pdb:5POJ|rcsb pdb:5POK|rcsb pdb:5POL|rcsb pdb:5POM|rcsb pdb:5PON|rcsb pdb:5POO|rcsb pdb:5POP|rcsb pdb:5POQ|refseq:XP_016884206.1|rcsb pdb:5POR|rcsb pdb:5POS|rcsb pdb:5POT|rcsb pdb:5POU|rcsb pdb:5POV|rcsb pdb:5POW|rcsb pdb:5POX|rcsb pdb:5POY|rcsb pdb:5POZ|rcsb pdb:5PP0|rcsb pdb:5PP1|rcsb pdb:5PP2|rcsb pdb:5PP3|rcsb pdb:5PP4|rcsb pdb:5PP5|rcsb pdb:5PP6|rcsb pdb:5PP7|rcsb pdb:5PP8|rcsb pdb:5PP9|rcsb pdb:5PPA|rcsb pdb:5PPB|rcsb pdb:5PPC|rcsb pdb:5PPD|rcsb pdb:5PPE|rcsb pdb:5PPF|rcsb pdb:5PPG|rcsb pdb:5PPH|rcsb pdb:5PPI|rcsb pdb:5PPJ|rcsb pdb:5PPK|rcsb pdb:5PPL|rcsb pdb:5PPM|rcsb pdb:5PPN|rcsb pdb:5PPO|rcsb pdb:5PPP|rcsb pdb:5PPQ|rcsb pdb:5PPR|rcsb pdb:5PPS|rcsb pdb:5PPT|rcsb pdb:5PPU|rcsb pdb:5PPV|rcsb pdb:5PPW|rcsb pdb:5PPX|rcsb pdb:5PPY|rcsb pdb:5PPZ|rcsb pdb:5PQ0|rcsb pdb:5PQ1|rcsb pdb:5PQ2|rcsb pdb:5PQ3|rcsb pdb:5PQ4|rcsb pdb:5PQ5|rcsb pdb:5PQ6|rcsb pdb:5PQ7|rcsb pdb:5PQ8|rcsb pdb:5PQ9|rcsb pdb:5PQA|rcsb pdb:5PQB|rcsb pdb:5PQC|rcsb pdb:5PQD|rcsb pdb:5PQE|rcsb pdb:5PQF|rcsb pdb:5PQG|rcsb pdb:5PQH|rcsb pdb:5PQI|rcsb pdb:5PQJ|rcsb pdb:5PQK|rcsb pdb:5PQL|rcsb pdb:5PQM|rcsb pdb:5PQN|rcsb pdb:5PQO|rcsb pdb:5PQP|rcsb pdb:5PQQ|rcsb pdb:5PQR|rcsb pdb:5PQS|rcsb pdb:5PQT|rcsb pdb:5PQU|rcsb pdb:5PQV|rcsb pdb:5PQW|rcsb pdb:5PQX|rcsb pdb:5PQY|rcsb pdb:5PQZ|rcsb pdb:5PR0|rcsb pdb:5PR1|rcsb pdb:5PR2|rcsb pdb:5PR4|rcsb pdb:5PR5|rcsb pdb:5PR6|rcsb pdb:5PR7|rcsb pdb:5PR8|rcsb pdb:5PST|rcsb pdb:5PR9|rcsb pdb:5PRA|rcsb pdb:5PRB|rcsb pdb:5PRD|rcsb pdb:5PRE|rcsb pdb:5PRF|rcsb pdb:5PRG|rcsb pdb:5PRH|rcsb pdb:5PRI|rcsb pdb:5PRJ|rcsb pdb:5PRK|rcsb pdb:5PRL|rcsb pdb:5PRM|rcsb pdb:5PRO|rcsb pdb:5PRP|rcsb pdb:5PRQ|rcsb pdb:5PRR|rcsb pdb:5PRS|rcsb pdb:5PRT|rcsb pdb:5PRU|rcsb pdb:5PRV|rcsb pdb:5PRW|rcsb pdb:5PRX|rcsb pdb:5PRY|rcsb pdb:5PRZ|rcsb pdb:5PS0|rcsb pdb:5PS1|rcsb pdb:5PS2|rcsb pdb:5PS3|rcsb pdb:5PS4|rcsb pdb:5PS5|rcsb pdb:5PS6|rcsb pdb:5PS7|rcsb pdb:5PS8|rcsb pdb:5PS9|rcsb pdb:5PSA|rcsb pdb:5PSB|rcsb pdb:5PSC|rcsb pdb:5PSD|rcsb pdb:5PSE|rcsb pdb:5PSF|rcsb pdb:5PSG|rcsb pdb:5PSH|rcsb pdb:5PSI|rcsb pdb:5PSJ|rcsb pdb:5PSK|rcsb pdb:5PSL|rcsb pdb:5PSM|rcsb pdb:5PSN|rcsb pdb:5PSO|rcsb pdb:5PSP|rcsb pdb:5PSQ|rcsb pdb:5PSR|rcsb pdb:5PSS|rcsb pdb:5PSU|rcsb pdb:5PSV|rcsb pdb:5PSW|rcsb pdb:5PSX|rcsb pdb:5PSY|rcsb pdb:5PSZ|rcsb pdb:5PT0|rcsb pdb:5PT1|rcsb pdb:5PT2|rcsb pdb:5PT3|rcsb pdb:5PT4|rcsb pdb:5PT5|rcsb pdb:5PT6|rcsb pdb:5PT7|rcsb pdb:5PT8|rcsb pdb:5PT9|rcsb pdb:5PTA|rcsb pdb:5PTB|rcsb pdb:5PTC|rcsb pdb:5PTE|rcsb pdb:5PTF|rcsb pdb:5PTG|rcsb pdb:5PTH|rcsb pdb:5PTJ|rcsb pdb:5PTK|rcsb pdb:5PTL|rcsb pdb:5PTM|rcsb pdb:5PTN|rcsb pdb:5PTO|rcsb pdb:5PTQ|rcsb pdb:5PTR|rcsb pdb:5PTS|rcsb pdb:5PTT|rcsb pdb:5PTU|rcsb pdb:5PTV|rcsb pdb:5PTW|rcsb pdb:5PTX|rcsb pdb:5PTY|rcsb pdb:5PTZ|rcsb pdb:5PU0|rcsb pdb:5PU1|rcsb pdb:5PU2|rcsb pdb:5PU3|rcsb pdb:5PU4|rcsb pdb:5PU5|rcsb pdb:5PU6|rcsb pdb:5PU7|rcsb pdb:5PU8|rcsb pdb:5PU9|rcsb pdb:5PUA|rcsb pdb:5PUB|rcsb pdb:5PUC|rcsb pdb:5PUD|rcsb pdb:5PUE|rcsb pdb:5PUF|rcsb pdb:5PUG|rcsb pdb:5PUH|rcsb pdb:5PUI|rcsb pdb:5PUJ|rcsb pdb:5PUK|rcsb pdb:5PUL|rcsb pdb:5PUM|rcsb pdb:5PUN|rcsb pdb:5PUO|rcsb pdb:5PUP|rcsb pdb:5PUQ|rcsb pdb:5PUR|rcsb pdb:5PUS|rcsb pdb:5PUT|rcsb pdb:5PUU|rcsb pdb:5PUV|rcsb pdb:5PUW|rcsb pdb:5PUX|rcsb pdb:5PUY|rcsb pdb:5PUZ|rcsb pdb:5PV0|rcsb pdb:5PV1|rcsb pdb:5PV2|rcsb pdb:5PV3|rcsb pdb:5PV4|rcsb pdb:5PV5|rcsb pdb:5PV6|rcsb pdb:5PV7|rcsb pdb:5PV8|rcsb pdb:5PV9|rcsb pdb:5PVA|rcsb pdb:5PVB|rcsb pdb:5PVC|rcsb pdb:5PVD|rcsb pdb:5PVE|rcsb pdb:5PVF|rcsb pdb:5PVG|rcsb pdb:5PVH|rcsb pdb:5PVI|rcsb pdb:5PVJ|rcsb pdb:5PVK|rcsb pdb:5PVL|rcsb pdb:5PVM|rcsb pdb:5PVN|rcsb pdb:5PVO|rcsb pdb:5PVP|rcsb pdb:5PVQ|rcsb pdb:5PVR|rcsb pdb:5PVS|rcsb pdb:5PVT|rcsb pdb:5PVU|rcsb pdb:5PVV|rcsb pdb:5PVW|rcsb pdb:5PVX|rcsb pdb:5PVY|rcsb pdb:5PVZ|rcsb pdb:5PW0|rcsb pdb:5PW1|rcsb pdb:5PW2|rcsb pdb:5PW3|rcsb pdb:5PW4|rcsb pdb:5PW5|rcsb pdb:5PW6|rcsb pdb:5PW7|rcsb pdb:5PW8|rcsb pdb:5PW9|rcsb pdb:5PWA|rcsb pdb:5PWB|rcsb pdb:6IN2|rcsb pdb:6MAJ|rcsb pdb:6MAK|rcsb pdb:7LH9|reactome:R-HSA-3214847|reactome:R-HSA-6804758|refseq:NP_001291737.1|refseq:NP_001291738.1|refseq:XP_016884204.1|refseq:XP_016884205.1 refseq:NP_060366.1|ensembl:ENSG00000101193(gene)|ensembl:ENST00000266069(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030054"(cell junction)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR013144(CT11-RanBPM)|interpro:IPR024964|mint:Q9NWU2|rcsb pdb:7NSC - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:P/L2yjwT2CYr7rO64cYcdahm2z09606 rogid:P0HsK72KT6OPKKw7lVSJ/FiY4CU9606 rigid:61ptXJ352/6k7OWcQc+mQW/uIAg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95696 uniprotkb:P04637 intact:EBI-714754|uniprotkb:A6ZJA4|ensembl:ENSP00000216267|ensembl:ENSP00000384076 intact:EBI-366083|uniprotkb:Q15086|uniprotkb:Q15087|uniprotkb:Q15088|uniprotkb:Q16535|uniprotkb:Q16807|uniprotkb:Q16808|uniprotkb:Q16809|uniprotkb:Q16810|uniprotkb:Q16811|uniprotkb:Q16848|uniprotkb:Q86UG1|uniprotkb:Q8J016|uniprotkb:Q99659|uniprotkb:Q9BTM4|uniprotkb:Q9HAQ8|uniprotkb:Q9NP68|uniprotkb:Q9NPJ2|uniprotkb:Q9NZD0|uniprotkb:Q9UBI2|uniprotkb:Q9UQ61|ensembl:ENSP00000269305|ensembl:ENSP00000391478|intact:EBI-28980681|uniprotkb:Q2XN98|uniprotkb:Q3LRW1|uniprotkb:Q3LRW2|uniprotkb:Q3LRW3|uniprotkb:Q3LRW4|uniprotkb:Q3LRW5 psi-mi:brd1_human(display_long)|uniprotkb:BR140-like protein(gene name synonym)|uniprotkb:BRD1(gene name)|psi-mi:BRD1(display_short)|uniprotkb:BRL(gene name synonym)|uniprotkb:BRPF2(gene name synonym)|uniprotkb:Bromodomain and PHD finger-containing protein 2(gene name synonym) psi-mi:p53_human(display_long)|uniprotkb:TP53(gene name)|psi-mi:TP53(display_short)|uniprotkb:P53(gene name synonym)|uniprotkb:Tumor suppressor p53(gene name synonym)|uniprotkb:Phosphoprotein p53(gene name synonym)|uniprotkb:Antigen NY-CO-13(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476670|imex:IM-26985-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0036409"(histone H3-K14 acetyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051602"(response to electrical stimulus)|ensembl:ENSG00000100425(gene)|ensembl:ENST00000216267(transcript)|ensembl:ENST00000404034(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0016607"(nuclear speck)|go:"GO:0030425"(dendrite)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042004|interpro:IPR042009|mint:O95696|rcsb pdb:2KU3|rcsb pdb:2L43|rcsb pdb:2LQ6|rcsb pdb:3LYI|rcsb pdb:3RCW|rcsb pdb:4Z02|rcsb pdb:5AME|rcsb pdb:5AMF|rcsb pdb:5FG6|rcsb pdb:5GK9|rcsb pdb:5N49|rcsb pdb:5PNX|rcsb pdb:5PNY|rcsb pdb:5PNZ|rcsb pdb:5PO0|rcsb pdb:5PO1|rcsb pdb:5PO2|rcsb pdb:5PO3|rcsb pdb:5PO4|rcsb pdb:5PO5|rcsb pdb:5PO6|rcsb pdb:5PO7|rcsb pdb:5PO8|rcsb pdb:5PO9|rcsb pdb:5POA|rcsb pdb:5POB|rcsb pdb:5POC|rcsb pdb:5POD|rcsb pdb:5POE|rcsb pdb:5POF|rcsb pdb:5POG|rcsb pdb:5POH|rcsb pdb:5POI|rcsb pdb:5POJ|rcsb pdb:5POK|rcsb pdb:5POL|rcsb pdb:5POM|rcsb pdb:5PON|rcsb pdb:5POO|rcsb pdb:5POP|rcsb pdb:5POQ|refseq:XP_016884206.1|rcsb pdb:5POR|rcsb pdb:5POS|rcsb pdb:5POT|rcsb pdb:5POU|rcsb pdb:5POV|rcsb pdb:5POW|rcsb pdb:5POX|rcsb pdb:5POY|rcsb pdb:5POZ|rcsb pdb:5PP0|rcsb pdb:5PP1|rcsb pdb:5PP2|rcsb pdb:5PP3|rcsb pdb:5PP4|rcsb pdb:5PP5|rcsb pdb:5PP6|rcsb pdb:5PP7|rcsb pdb:5PP8|rcsb pdb:5PP9|rcsb pdb:5PPA|rcsb pdb:5PPB|rcsb pdb:5PPC|rcsb pdb:5PPD|rcsb pdb:5PPE|rcsb pdb:5PPF|rcsb pdb:5PPG|rcsb pdb:5PPH|rcsb pdb:5PPI|rcsb pdb:5PPJ|rcsb pdb:5PPK|rcsb pdb:5PPL|rcsb pdb:5PPM|rcsb pdb:5PPN|rcsb pdb:5PPO|rcsb pdb:5PPP|rcsb pdb:5PPQ|rcsb pdb:5PPR|rcsb pdb:5PPS|rcsb pdb:5PPT|rcsb pdb:5PPU|rcsb pdb:5PPV|rcsb pdb:5PPW|rcsb pdb:5PPX|rcsb pdb:5PPY|rcsb pdb:5PPZ|rcsb pdb:5PQ0|rcsb pdb:5PQ1|rcsb pdb:5PQ2|rcsb pdb:5PQ3|rcsb pdb:5PQ4|rcsb pdb:5PQ5|rcsb pdb:5PQ6|rcsb pdb:5PQ7|rcsb pdb:5PQ8|rcsb pdb:5PQ9|rcsb pdb:5PQA|rcsb pdb:5PQB|rcsb pdb:5PQC|rcsb pdb:5PQD|rcsb pdb:5PQE|rcsb pdb:5PQF|rcsb pdb:5PQG|rcsb pdb:5PQH|rcsb pdb:5PQI|rcsb pdb:5PQJ|rcsb pdb:5PQK|rcsb pdb:5PQL|rcsb pdb:5PQM|rcsb pdb:5PQN|rcsb pdb:5PQO|rcsb pdb:5PQP|rcsb pdb:5PQQ|rcsb pdb:5PQR|rcsb pdb:5PQS|rcsb pdb:5PQT|rcsb pdb:5PQU|rcsb pdb:5PQV|rcsb pdb:5PQW|rcsb pdb:5PQX|rcsb pdb:5PQY|rcsb pdb:5PQZ|rcsb pdb:5PR0|rcsb pdb:5PR1|rcsb pdb:5PR2|rcsb pdb:5PR4|rcsb pdb:5PR5|rcsb pdb:5PR6|rcsb pdb:5PR7|rcsb pdb:5PR8|rcsb pdb:5PST|rcsb pdb:5PR9|rcsb pdb:5PRA|rcsb pdb:5PRB|rcsb pdb:5PRD|rcsb pdb:5PRE|rcsb pdb:5PRF|rcsb pdb:5PRG|rcsb pdb:5PRH|rcsb pdb:5PRI|rcsb pdb:5PRJ|rcsb pdb:5PRK|rcsb pdb:5PRL|rcsb pdb:5PRM|rcsb pdb:5PRO|rcsb pdb:5PRP|rcsb pdb:5PRQ|rcsb pdb:5PRR|rcsb pdb:5PRS|rcsb pdb:5PRT|rcsb pdb:5PRU|rcsb pdb:5PRV|rcsb pdb:5PRW|rcsb pdb:5PRX|rcsb pdb:5PRY|rcsb pdb:5PRZ|rcsb pdb:5PS0|rcsb pdb:5PS1|rcsb pdb:5PS2|rcsb pdb:5PS3|rcsb pdb:5PS4|rcsb pdb:5PS5|rcsb pdb:5PS6|rcsb pdb:5PS7|rcsb pdb:5PS8|rcsb pdb:5PS9|rcsb pdb:5PSA|rcsb pdb:5PSB|rcsb pdb:5PSC|rcsb pdb:5PSD|rcsb pdb:5PSE|rcsb pdb:5PSF|rcsb pdb:5PSG|rcsb pdb:5PSH|rcsb pdb:5PSI|rcsb pdb:5PSJ|rcsb pdb:5PSK|rcsb pdb:5PSL|rcsb pdb:5PSM|rcsb pdb:5PSN|rcsb pdb:5PSO|rcsb pdb:5PSP|rcsb pdb:5PSQ|rcsb pdb:5PSR|rcsb pdb:5PSS|rcsb pdb:5PSU|rcsb pdb:5PSV|rcsb pdb:5PSW|rcsb pdb:5PSX|rcsb pdb:5PSY|rcsb pdb:5PSZ|rcsb pdb:5PT0|rcsb pdb:5PT1|rcsb pdb:5PT2|rcsb pdb:5PT3|rcsb pdb:5PT4|rcsb pdb:5PT5|rcsb pdb:5PT6|rcsb pdb:5PT7|rcsb pdb:5PT8|rcsb pdb:5PT9|rcsb pdb:5PTA|rcsb pdb:5PTB|rcsb pdb:5PTC|rcsb pdb:5PTE|rcsb pdb:5PTF|rcsb pdb:5PTG|rcsb pdb:5PTH|rcsb pdb:5PTJ|rcsb pdb:5PTK|rcsb pdb:5PTL|rcsb pdb:5PTM|rcsb pdb:5PTN|rcsb pdb:5PTO|rcsb pdb:5PTQ|rcsb pdb:5PTR|rcsb pdb:5PTS|rcsb pdb:5PTT|rcsb pdb:5PTU|rcsb pdb:5PTV|rcsb pdb:5PTW|rcsb pdb:5PTX|rcsb pdb:5PTY|rcsb pdb:5PTZ|rcsb pdb:5PU0|rcsb pdb:5PU1|rcsb pdb:5PU2|rcsb pdb:5PU3|rcsb pdb:5PU4|rcsb pdb:5PU5|rcsb pdb:5PU6|rcsb pdb:5PU7|rcsb pdb:5PU8|rcsb pdb:5PU9|rcsb pdb:5PUA|rcsb pdb:5PUB|rcsb pdb:5PUC|rcsb pdb:5PUD|rcsb pdb:5PUE|rcsb pdb:5PUF|rcsb pdb:5PUG|rcsb pdb:5PUH|rcsb pdb:5PUI|rcsb pdb:5PUJ|rcsb pdb:5PUK|rcsb pdb:5PUL|rcsb pdb:5PUM|rcsb pdb:5PUN|rcsb pdb:5PUO|rcsb pdb:5PUP|rcsb pdb:5PUQ|rcsb pdb:5PUR|rcsb pdb:5PUS|rcsb pdb:5PUT|rcsb pdb:5PUU|rcsb pdb:5PUV|rcsb pdb:5PUW|rcsb pdb:5PUX|rcsb pdb:5PUY|rcsb pdb:5PUZ|rcsb pdb:5PV0|rcsb pdb:5PV1|rcsb pdb:5PV2|rcsb pdb:5PV3|rcsb pdb:5PV4|rcsb pdb:5PV5|rcsb pdb:5PV6|rcsb pdb:5PV7|rcsb pdb:5PV8|rcsb pdb:5PV9|rcsb pdb:5PVA|rcsb pdb:5PVB|rcsb pdb:5PVC|rcsb pdb:5PVD|rcsb pdb:5PVE|rcsb pdb:5PVF|rcsb pdb:5PVG|rcsb pdb:5PVH|rcsb pdb:5PVI|rcsb pdb:5PVJ|rcsb pdb:5PVK|rcsb pdb:5PVL|rcsb pdb:5PVM|rcsb pdb:5PVN|rcsb pdb:5PVO|rcsb pdb:5PVP|rcsb pdb:5PVQ|rcsb pdb:5PVR|rcsb pdb:5PVS|rcsb pdb:5PVT|rcsb pdb:5PVU|rcsb pdb:5PVV|rcsb pdb:5PVW|rcsb pdb:5PVX|rcsb pdb:5PVY|rcsb pdb:5PVZ|rcsb pdb:5PW0|rcsb pdb:5PW1|rcsb pdb:5PW2|rcsb pdb:5PW3|rcsb pdb:5PW4|rcsb pdb:5PW5|rcsb pdb:5PW6|rcsb pdb:5PW7|rcsb pdb:5PW8|rcsb pdb:5PW9|rcsb pdb:5PWA|rcsb pdb:5PWB|rcsb pdb:6IN2|rcsb pdb:6MAJ|rcsb pdb:6MAK|rcsb pdb:7LH9|reactome:R-HSA-3214847|reactome:R-HSA-6804758|refseq:NP_001291737.1|refseq:NP_001291738.1|refseq:XP_016884204.1|refseq:XP_016884205.1 refseq:NP_001263624.1|refseq:NP_001263625.1|ensembl:ENSG00000141510(gene)|ensembl:ENST00000269305(transcript)|ensembl:ENST00000445888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0002020"(protease binding)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0031497"(chromatin assembly)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034103"(regulation of tissue remodeling)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035033"(histone deacetylase regulator activity)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035690"|go:"GO:0035794"(positive regulation of mitochondrial membrane permeability)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0006983"(ER overload response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007369"(gastrulation)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0043621"(protein self-association)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048512"(circadian behavior)|go:"GO:0048539"(bone marrow development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0062100"(positive regulation of programmed necrotic cell death)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070245"(positive regulation of thymocyte apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071494"(cellular response to UV-C)|go:"GO:0072331"(signal transduction by p53 class mediator)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:0090399"(replicative senescence)|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097252"(oligodendrocyte apoptotic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1902253"(regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904024"(negative regulation of glucose catabolic process to lactate via pyruvate)|go:"GO:1905856"(negative regulation of pentose-phosphate shunt)|go:"GO:1990144"(intrinsic apoptotic signaling pathway in response to hypoxia)|go:"GO:1990248"(regulation of transcription from RNA polymerase II promoter in response to DNA damage)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000269"(regulation of fibroblast apoptotic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009299"(mRNA transcription)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009651"(response to salt stress)|go:"GO:0010165"(response to X-ray)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016032"(viral process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013872("p53 transactivation domain (TAD)")|interpro:IPR036674|interpro:IPR040926|rcsb pdb:2ATA|rcsb pdb:2B3G|rcsb pdb:2BIM|rcsb pdb:2BIN|rcsb pdb:2BIO|rcsb pdb:2BIP|rcsb pdb:2AHI|rcsb pdb:2BIQ|rcsb pdb:2F1X|rcsb pdb:2FEJ|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2GS0|rcsb pdb:2H1L|rcsb pdb:2H2D|rcsb pdb:2H2F|rcsb pdb:2H4F|rcsb pdb:2H4H|rcsb pdb:2H4J|rcsb pdb:2H59|rcsb pdb:2J0Z|rcsb pdb:2J10|rcsb pdb:2J11|rcsb pdb:2J1W|rcsb pdb:2J1X|rcsb pdb:2J1Y|rcsb pdb:2J1Z|rcsb pdb:2J20|rcsb pdb:2J21|rcsb pdb:2K8F|rcsb pdb:2L14|rcsb pdb:2LY4|rcsb pdb:2MEJ|rcsb pdb:2MWO|rcsb pdb:2MWP|rcsb pdb:2MWY|rcsb pdb:2MZD|rcsb pdb:2OCJ|rcsb pdb:2PCX|rcsb pdb:1A1U|rcsb pdb:1AIE|rcsb pdb:1C26|rcsb pdb:1DT7|rcsb pdb:1GZH|rcsb pdb:1H26|rcsb pdb:1HS5|rcsb pdb:1JSP|rcsb pdb:1KZY|rcsb pdb:1MA3|rcsb pdb:1OLG|rcsb pdb:1OLH|rcsb pdb:1PES|rcsb pdb:1PET|mint:P04637|rcsb pdb:1SAE|rcsb pdb:1SAF|rcsb pdb:1SAK|rcsb pdb:1SAL|rcsb pdb:1TSR|rcsb pdb:1TUP|rcsb pdb:1UOL|rcsb pdb:1XQH|rcsb pdb:1YC5|rcsb pdb:1YCQ|rcsb pdb:1YCR|rcsb pdb:1YCS|rcsb pdb:2AC0|rcsb pdb:2ADY|refseq:NP_000537.3|refseq:NP_001119584.1|refseq:NP_001119585.1|refseq:NP_001119586.1|refseq:NP_001119587.1|refseq:NP_001119588.1|refseq:NP_001119589.1|rcsb pdb:2RUK|rcsb pdb:2VUK|rcsb pdb:3Q06|rcsb pdb:2WGX|rcsb pdb:2X0U|rcsb pdb:2X0V|rcsb pdb:2X0W|rcsb pdb:2XWR|rcsb pdb:2YBG|rcsb pdb:2YDR|rcsb pdb:2Z5S|rcsb pdb:2Z5T|rcsb pdb:3SAK|rcsb pdb:3D05|rcsb pdb:3D06|rcsb pdb:3D07|rcsb pdb:3D08|rcsb pdb:3D09|rcsb pdb:3D0A|rcsb pdb:3DAB|rcsb pdb:3DAC|rcsb pdb:3IGK|rcsb pdb:3IGL|rcsb pdb:3KMD|rcsb pdb:3TG5|rcsb pdb:3KZ8|rcsb pdb:3LW1|rcsb pdb:3OQ5|rcsb pdb:3PDH|rcsb pdb:3Q01|rcsb pdb:3Q05|rcsb pdb:3TS8|rcsb pdb:3ZME|rcsb pdb:4AGM|rcsb pdb:4AGN|rcsb pdb:4AGO|rcsb pdb:4AGP|rcsb pdb:4AGQ|rcsb pdb:4BUZ|rcsb pdb:4BV2|rcsb pdb:4HFZ|rcsb pdb:4HJE|rcsb pdb:4IBQ|rcsb pdb:4IBS|rcsb pdb:4IBT|rcsb pdb:4IBU|rcsb pdb:4IBV|rcsb pdb:4IBW|rcsb pdb:4IBY|rcsb pdb:4IBZ|rcsb pdb:4IJT|rcsb pdb:4KVP|rcsb pdb:4LO9|rcsb pdb:4LOE|rcsb pdb:4LOF|rcsb pdb:4MZI|rcsb pdb:4MZR|rcsb pdb:4QO1|rcsb pdb:4RP6|rcsb pdb:4RP7|rcsb pdb:4X34|rcsb pdb:4XR8|rcsb pdb:4ZZJ|rcsb pdb:5A7B|rcsb pdb:5AB9|rcsb pdb:5ABA|rcsb pdb:4AGL|rcsb pdb:5AOI|rcsb pdb:5AOJ|rcsb pdb:5AOK|rcsb pdb:5AOL|rcsb pdb:5AOM|rcsb pdb:6XRE|rcsb pdb:7BWN|rcsb pdb:7DHY|rcsb pdb:7DHZ|rcsb pdb:7EL4|reactome:R-HSA-111448|reactome:R-HSA-139915|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-2559586|reactome:R-HSA-3232118|reactome:R-HSA-349425|reactome:R-HSA-390471|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5693565|reactome:R-HSA-6785807|reactome:R-HSA-6796648|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804114|reactome:R-HSA-6804115|reactome:R-HSA-6804116|reactome:R-HSA-6804754|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-69473|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8853884|reactome:R-HSA-8941855|reactome:R-HSA-8943724|reactome:R-HSA-983231|rcsb pdb:5ECG|rcsb pdb:5G4M|rcsb pdb:5G4N|rcsb pdb:5BUA|rcsb pdb:5G4O|rcsb pdb:5HOU|rcsb pdb:5HP0|rcsb pdb:5HPD|rcsb pdb:5LAP|rcsb pdb:5LGY|rcsb pdb:5MCT|rcsb pdb:5MCU|rcsb pdb:5MCV|rcsb pdb:5MCW|rcsb pdb:5MF7|rcsb pdb:5MG7|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5O1A|rcsb pdb:5O1B|rcsb pdb:5O1C|rcsb pdb:5O1D|rcsb pdb:5O1E|rcsb pdb:5O1F|rcsb pdb:5O1G|rcsb pdb:5O1H|rcsb pdb:5O1I|rcsb pdb:5OL0|rcsb pdb:5UN8|rcsb pdb:5XZC|rcsb pdb:6FF9|rcsb pdb:6FJ5|rcsb pdb:6GGA|rcsb pdb:6GGB|rcsb pdb:6GGC|rcsb pdb:6GGD|rcsb pdb:6GGE|rcsb pdb:6GGF|rcsb pdb:6LHD|rcsb pdb:6R5L|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:6RWS|rcsb pdb:6RWU|rcsb pdb:6RX2|rcsb pdb:6RZ3|rcsb pdb:6S39|rcsb pdb:6S40|rcsb pdb:6S9Q|rcsb pdb:6SHZ|rcsb pdb:6SI0|rcsb pdb:6SI1|rcsb pdb:6SI2|rcsb pdb:6SI3|rcsb pdb:6SI4|rcsb pdb:6SIN|rcsb pdb:6SIO|rcsb pdb:6SIP|rcsb pdb:6SIQ|rcsb pdb:6SL6|rcsb pdb:6SLV|rcsb pdb:6T58|rcsb pdb:6V4F|rcsb pdb:6V4H|rcsb pdb:6VQO|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6S3C|ensembl:ENSP00000269305|ensembl:ENST00000420246|ensembl:ENSP00000391127|ensembl:ENSP00000391478|ensembl:ENST00000455263|ensembl:ENSP00000398846|ensembl:ENST00000504290|ensembl:ENSP00000484409|ensembl:ENST00000504937|ensembl:ENSP00000481179|ensembl:ENST00000510385|ensembl:ENSP00000478499|ensembl:ENST00000610292|ensembl:ENSP00000478219|ensembl:ENST00000610538|ensembl:ENSP00000480868|ensembl:ENST00000619485|ensembl:ENSP00000482537|ensembl:ENST00000620739|ensembl:ENSP00000481638|ensembl:ENST00000622645|ensembl:ENSP00000482222|refseq:NP_001119590.1|refseq:NP_001263626.1|refseq:NP_001263627.1|refseq:NP_001263628.1|refseq:NP_001263689.1|refseq:NP_001263690.1|dip:DIP-368N - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:P/L2yjwT2CYr7rO64cYcdahm2z09606 rogid:fGN3kSCGIpi/D6d/X5kaB0Xu8/k9606 rigid:61ptXJ352/6k7OWcQc+mQW/uIAg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95696 uniprotkb:P49959 intact:EBI-714754|uniprotkb:A6ZJA4|ensembl:ENSP00000216267|ensembl:ENSP00000384076 intact:EBI-396513|uniprotkb:O43475|uniprotkb:B3KTC7|ensembl:ENSP00000325863 psi-mi:brd1_human(display_long)|uniprotkb:BR140-like protein(gene name synonym)|uniprotkb:BRD1(gene name)|psi-mi:BRD1(display_short)|uniprotkb:BRL(gene name synonym)|uniprotkb:BRPF2(gene name synonym)|uniprotkb:Bromodomain and PHD finger-containing protein 2(gene name synonym) psi-mi:mre11_human(display_long)|uniprotkb:MRE11(gene name)|psi-mi:MRE11(display_short)|uniprotkb:Double-strand break repair protein MRE11A(gene name synonym)|uniprotkb:HNGS1(gene name synonym)|uniprotkb:MRE11A(gene name synonym)|uniprotkb:Meiotic recombination 11 homolog 1(gene name synonym)|uniprotkb:Meiotic recombination 11 homolog A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476670|imex:IM-26985-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0036409"(histone H3-K14 acetyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051602"(response to electrical stimulus)|ensembl:ENSG00000100425(gene)|ensembl:ENST00000216267(transcript)|ensembl:ENST00000404034(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0016607"(nuclear speck)|go:"GO:0030425"(dendrite)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042004|interpro:IPR042009|mint:O95696|rcsb pdb:2KU3|rcsb pdb:2L43|rcsb pdb:2LQ6|rcsb pdb:3LYI|rcsb pdb:3RCW|rcsb pdb:4Z02|rcsb pdb:5AME|rcsb pdb:5AMF|rcsb pdb:5FG6|rcsb pdb:5GK9|rcsb pdb:5N49|rcsb pdb:5PNX|rcsb pdb:5PNY|rcsb pdb:5PNZ|rcsb pdb:5PO0|rcsb pdb:5PO1|rcsb pdb:5PO2|rcsb pdb:5PO3|rcsb pdb:5PO4|rcsb pdb:5PO5|rcsb pdb:5PO6|rcsb pdb:5PO7|rcsb pdb:5PO8|rcsb pdb:5PO9|rcsb pdb:5POA|rcsb pdb:5POB|rcsb pdb:5POC|rcsb pdb:5POD|rcsb pdb:5POE|rcsb pdb:5POF|rcsb pdb:5POG|rcsb pdb:5POH|rcsb pdb:5POI|rcsb pdb:5POJ|rcsb pdb:5POK|rcsb pdb:5POL|rcsb pdb:5POM|rcsb pdb:5PON|rcsb pdb:5POO|rcsb pdb:5POP|rcsb pdb:5POQ|refseq:XP_016884206.1|rcsb pdb:5POR|rcsb pdb:5POS|rcsb pdb:5POT|rcsb pdb:5POU|rcsb pdb:5POV|rcsb pdb:5POW|rcsb pdb:5POX|rcsb pdb:5POY|rcsb pdb:5POZ|rcsb pdb:5PP0|rcsb pdb:5PP1|rcsb pdb:5PP2|rcsb pdb:5PP3|rcsb pdb:5PP4|rcsb pdb:5PP5|rcsb pdb:5PP6|rcsb pdb:5PP7|rcsb pdb:5PP8|rcsb pdb:5PP9|rcsb pdb:5PPA|rcsb pdb:5PPB|rcsb pdb:5PPC|rcsb pdb:5PPD|rcsb pdb:5PPE|rcsb pdb:5PPF|rcsb pdb:5PPG|rcsb pdb:5PPH|rcsb pdb:5PPI|rcsb pdb:5PPJ|rcsb pdb:5PPK|rcsb pdb:5PPL|rcsb pdb:5PPM|rcsb pdb:5PPN|rcsb pdb:5PPO|rcsb pdb:5PPP|rcsb pdb:5PPQ|rcsb pdb:5PPR|rcsb pdb:5PPS|rcsb pdb:5PPT|rcsb pdb:5PPU|rcsb pdb:5PPV|rcsb pdb:5PPW|rcsb pdb:5PPX|rcsb pdb:5PPY|rcsb pdb:5PPZ|rcsb pdb:5PQ0|rcsb pdb:5PQ1|rcsb pdb:5PQ2|rcsb pdb:5PQ3|rcsb pdb:5PQ4|rcsb pdb:5PQ5|rcsb pdb:5PQ6|rcsb pdb:5PQ7|rcsb pdb:5PQ8|rcsb pdb:5PQ9|rcsb pdb:5PQA|rcsb pdb:5PQB|rcsb pdb:5PQC|rcsb pdb:5PQD|rcsb pdb:5PQE|rcsb pdb:5PQF|rcsb pdb:5PQG|rcsb pdb:5PQH|rcsb pdb:5PQI|rcsb pdb:5PQJ|rcsb pdb:5PQK|rcsb pdb:5PQL|rcsb pdb:5PQM|rcsb pdb:5PQN|rcsb pdb:5PQO|rcsb pdb:5PQP|rcsb pdb:5PQQ|rcsb pdb:5PQR|rcsb pdb:5PQS|rcsb pdb:5PQT|rcsb pdb:5PQU|rcsb pdb:5PQV|rcsb pdb:5PQW|rcsb pdb:5PQX|rcsb pdb:5PQY|rcsb pdb:5PQZ|rcsb pdb:5PR0|rcsb pdb:5PR1|rcsb pdb:5PR2|rcsb pdb:5PR4|rcsb pdb:5PR5|rcsb pdb:5PR6|rcsb pdb:5PR7|rcsb pdb:5PR8|rcsb pdb:5PST|rcsb pdb:5PR9|rcsb pdb:5PRA|rcsb pdb:5PRB|rcsb pdb:5PRD|rcsb pdb:5PRE|rcsb pdb:5PRF|rcsb pdb:5PRG|rcsb pdb:5PRH|rcsb pdb:5PRI|rcsb pdb:5PRJ|rcsb pdb:5PRK|rcsb pdb:5PRL|rcsb pdb:5PRM|rcsb pdb:5PRO|rcsb pdb:5PRP|rcsb pdb:5PRQ|rcsb pdb:5PRR|rcsb pdb:5PRS|rcsb pdb:5PRT|rcsb pdb:5PRU|rcsb pdb:5PRV|rcsb pdb:5PRW|rcsb pdb:5PRX|rcsb pdb:5PRY|rcsb pdb:5PRZ|rcsb pdb:5PS0|rcsb pdb:5PS1|rcsb pdb:5PS2|rcsb pdb:5PS3|rcsb pdb:5PS4|rcsb pdb:5PS5|rcsb pdb:5PS6|rcsb pdb:5PS7|rcsb pdb:5PS8|rcsb pdb:5PS9|rcsb pdb:5PSA|rcsb pdb:5PSB|rcsb pdb:5PSC|rcsb pdb:5PSD|rcsb pdb:5PSE|rcsb pdb:5PSF|rcsb pdb:5PSG|rcsb pdb:5PSH|rcsb pdb:5PSI|rcsb pdb:5PSJ|rcsb pdb:5PSK|rcsb pdb:5PSL|rcsb pdb:5PSM|rcsb pdb:5PSN|rcsb pdb:5PSO|rcsb pdb:5PSP|rcsb pdb:5PSQ|rcsb pdb:5PSR|rcsb pdb:5PSS|rcsb pdb:5PSU|rcsb pdb:5PSV|rcsb pdb:5PSW|rcsb pdb:5PSX|rcsb pdb:5PSY|rcsb pdb:5PSZ|rcsb pdb:5PT0|rcsb pdb:5PT1|rcsb pdb:5PT2|rcsb pdb:5PT3|rcsb pdb:5PT4|rcsb pdb:5PT5|rcsb pdb:5PT6|rcsb pdb:5PT7|rcsb pdb:5PT8|rcsb pdb:5PT9|rcsb pdb:5PTA|rcsb pdb:5PTB|rcsb pdb:5PTC|rcsb pdb:5PTE|rcsb pdb:5PTF|rcsb pdb:5PTG|rcsb pdb:5PTH|rcsb pdb:5PTJ|rcsb pdb:5PTK|rcsb pdb:5PTL|rcsb pdb:5PTM|rcsb pdb:5PTN|rcsb pdb:5PTO|rcsb pdb:5PTQ|rcsb pdb:5PTR|rcsb pdb:5PTS|rcsb pdb:5PTT|rcsb pdb:5PTU|rcsb pdb:5PTV|rcsb pdb:5PTW|rcsb pdb:5PTX|rcsb pdb:5PTY|rcsb pdb:5PTZ|rcsb pdb:5PU0|rcsb pdb:5PU1|rcsb pdb:5PU2|rcsb pdb:5PU3|rcsb pdb:5PU4|rcsb pdb:5PU5|rcsb pdb:5PU6|rcsb pdb:5PU7|rcsb pdb:5PU8|rcsb pdb:5PU9|rcsb pdb:5PUA|rcsb pdb:5PUB|rcsb pdb:5PUC|rcsb pdb:5PUD|rcsb pdb:5PUE|rcsb pdb:5PUF|rcsb pdb:5PUG|rcsb pdb:5PUH|rcsb pdb:5PUI|rcsb pdb:5PUJ|rcsb pdb:5PUK|rcsb pdb:5PUL|rcsb pdb:5PUM|rcsb pdb:5PUN|rcsb pdb:5PUO|rcsb pdb:5PUP|rcsb pdb:5PUQ|rcsb pdb:5PUR|rcsb pdb:5PUS|rcsb pdb:5PUT|rcsb pdb:5PUU|rcsb pdb:5PUV|rcsb pdb:5PUW|rcsb pdb:5PUX|rcsb pdb:5PUY|rcsb pdb:5PUZ|rcsb pdb:5PV0|rcsb pdb:5PV1|rcsb pdb:5PV2|rcsb pdb:5PV3|rcsb pdb:5PV4|rcsb pdb:5PV5|rcsb pdb:5PV6|rcsb pdb:5PV7|rcsb pdb:5PV8|rcsb pdb:5PV9|rcsb pdb:5PVA|rcsb pdb:5PVB|rcsb pdb:5PVC|rcsb pdb:5PVD|rcsb pdb:5PVE|rcsb pdb:5PVF|rcsb pdb:5PVG|rcsb pdb:5PVH|rcsb pdb:5PVI|rcsb pdb:5PVJ|rcsb pdb:5PVK|rcsb pdb:5PVL|rcsb pdb:5PVM|rcsb pdb:5PVN|rcsb pdb:5PVO|rcsb pdb:5PVP|rcsb pdb:5PVQ|rcsb pdb:5PVR|rcsb pdb:5PVS|rcsb pdb:5PVT|rcsb pdb:5PVU|rcsb pdb:5PVV|rcsb pdb:5PVW|rcsb pdb:5PVX|rcsb pdb:5PVY|rcsb pdb:5PVZ|rcsb pdb:5PW0|rcsb pdb:5PW1|rcsb pdb:5PW2|rcsb pdb:5PW3|rcsb pdb:5PW4|rcsb pdb:5PW5|rcsb pdb:5PW6|rcsb pdb:5PW7|rcsb pdb:5PW8|rcsb pdb:5PW9|rcsb pdb:5PWA|rcsb pdb:5PWB|rcsb pdb:6IN2|rcsb pdb:6MAJ|rcsb pdb:6MAK|rcsb pdb:7LH9|reactome:R-HSA-3214847|reactome:R-HSA-6804758|refseq:NP_001291737.1|refseq:NP_001291738.1|refseq:XP_016884204.1|refseq:XP_016884205.1 refseq:NP_005581.2|refseq:NP_005582.1|refseq:XP_011541139.1|refseq:XP_016873261.1|dip:DIP-33238N|ensembl:ENSG00000020922(gene)|ensembl:ENST00000323929(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000019"(regulation of mitotic recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0016605"(PML body)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0097552"(mitochondrial double-strand break repair via homologous recombination)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|interpro:IPR003701(DNA repair exonuclease)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR007281(Mre11, DNA-binding)|interpro:IPR029052|interpro:IPR038487|interpro:IPR041796|mint:P49959|rcsb pdb:3T1I|reactome:R-HSA-1834949|reactome:R-HSA-2559586|reactome:R-HSA-3270619|reactome:R-HSA-5685938|reactome:R-HSA-5685939|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446 - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:P/L2yjwT2CYr7rO64cYcdahm2z09606 rogid:fgwgA0BcNZ9phGBaOSYjkldDgeI9606 rigid:61ptXJ352/6k7OWcQc+mQW/uIAg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95696 uniprotkb:P61981 intact:EBI-714754|uniprotkb:A6ZJA4|ensembl:ENSP00000216267|ensembl:ENSP00000384076 intact:EBI-359832|uniprotkb:O70457|uniprotkb:P35214|uniprotkb:Q6FH52|uniprotkb:Q9UDP2|uniprotkb:Q9UN99|ensembl:ENSP00000306330 psi-mi:brd1_human(display_long)|uniprotkb:BR140-like protein(gene name synonym)|uniprotkb:BRD1(gene name)|psi-mi:BRD1(display_short)|uniprotkb:BRL(gene name synonym)|uniprotkb:BRPF2(gene name synonym)|uniprotkb:Bromodomain and PHD finger-containing protein 2(gene name synonym) psi-mi:1433g_human(display_long)|uniprotkb:YWHAG(gene name)|psi-mi:YWHAG(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476670|imex:IM-26985-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0036409"(histone H3-K14 acetyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051602"(response to electrical stimulus)|ensembl:ENSG00000100425(gene)|ensembl:ENST00000216267(transcript)|ensembl:ENST00000404034(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0016607"(nuclear speck)|go:"GO:0030425"(dendrite)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042004|interpro:IPR042009|mint:O95696|rcsb pdb:2KU3|rcsb pdb:2L43|rcsb pdb:2LQ6|rcsb pdb:3LYI|rcsb pdb:3RCW|rcsb pdb:4Z02|rcsb pdb:5AME|rcsb pdb:5AMF|rcsb pdb:5FG6|rcsb pdb:5GK9|rcsb pdb:5N49|rcsb pdb:5PNX|rcsb pdb:5PNY|rcsb pdb:5PNZ|rcsb pdb:5PO0|rcsb pdb:5PO1|rcsb pdb:5PO2|rcsb pdb:5PO3|rcsb pdb:5PO4|rcsb pdb:5PO5|rcsb pdb:5PO6|rcsb pdb:5PO7|rcsb pdb:5PO8|rcsb pdb:5PO9|rcsb pdb:5POA|rcsb pdb:5POB|rcsb pdb:5POC|rcsb pdb:5POD|rcsb pdb:5POE|rcsb pdb:5POF|rcsb pdb:5POG|rcsb pdb:5POH|rcsb pdb:5POI|rcsb pdb:5POJ|rcsb pdb:5POK|rcsb pdb:5POL|rcsb pdb:5POM|rcsb pdb:5PON|rcsb pdb:5POO|rcsb pdb:5POP|rcsb pdb:5POQ|refseq:XP_016884206.1|rcsb pdb:5POR|rcsb pdb:5POS|rcsb pdb:5POT|rcsb pdb:5POU|rcsb pdb:5POV|rcsb pdb:5POW|rcsb pdb:5POX|rcsb pdb:5POY|rcsb pdb:5POZ|rcsb pdb:5PP0|rcsb pdb:5PP1|rcsb pdb:5PP2|rcsb pdb:5PP3|rcsb pdb:5PP4|rcsb pdb:5PP5|rcsb pdb:5PP6|rcsb pdb:5PP7|rcsb pdb:5PP8|rcsb pdb:5PP9|rcsb pdb:5PPA|rcsb pdb:5PPB|rcsb pdb:5PPC|rcsb pdb:5PPD|rcsb pdb:5PPE|rcsb pdb:5PPF|rcsb pdb:5PPG|rcsb pdb:5PPH|rcsb pdb:5PPI|rcsb pdb:5PPJ|rcsb pdb:5PPK|rcsb pdb:5PPL|rcsb pdb:5PPM|rcsb pdb:5PPN|rcsb pdb:5PPO|rcsb pdb:5PPP|rcsb pdb:5PPQ|rcsb pdb:5PPR|rcsb pdb:5PPS|rcsb pdb:5PPT|rcsb pdb:5PPU|rcsb pdb:5PPV|rcsb pdb:5PPW|rcsb pdb:5PPX|rcsb pdb:5PPY|rcsb pdb:5PPZ|rcsb pdb:5PQ0|rcsb pdb:5PQ1|rcsb pdb:5PQ2|rcsb pdb:5PQ3|rcsb pdb:5PQ4|rcsb pdb:5PQ5|rcsb pdb:5PQ6|rcsb pdb:5PQ7|rcsb pdb:5PQ8|rcsb pdb:5PQ9|rcsb pdb:5PQA|rcsb pdb:5PQB|rcsb pdb:5PQC|rcsb pdb:5PQD|rcsb pdb:5PQE|rcsb pdb:5PQF|rcsb pdb:5PQG|rcsb pdb:5PQH|rcsb pdb:5PQI|rcsb pdb:5PQJ|rcsb pdb:5PQK|rcsb pdb:5PQL|rcsb pdb:5PQM|rcsb pdb:5PQN|rcsb pdb:5PQO|rcsb pdb:5PQP|rcsb pdb:5PQQ|rcsb pdb:5PQR|rcsb pdb:5PQS|rcsb pdb:5PQT|rcsb pdb:5PQU|rcsb pdb:5PQV|rcsb pdb:5PQW|rcsb pdb:5PQX|rcsb pdb:5PQY|rcsb pdb:5PQZ|rcsb pdb:5PR0|rcsb pdb:5PR1|rcsb pdb:5PR2|rcsb pdb:5PR4|rcsb pdb:5PR5|rcsb pdb:5PR6|rcsb pdb:5PR7|rcsb pdb:5PR8|rcsb pdb:5PST|rcsb pdb:5PR9|rcsb pdb:5PRA|rcsb pdb:5PRB|rcsb pdb:5PRD|rcsb pdb:5PRE|rcsb pdb:5PRF|rcsb pdb:5PRG|rcsb pdb:5PRH|rcsb pdb:5PRI|rcsb pdb:5PRJ|rcsb pdb:5PRK|rcsb pdb:5PRL|rcsb pdb:5PRM|rcsb pdb:5PRO|rcsb pdb:5PRP|rcsb pdb:5PRQ|rcsb pdb:5PRR|rcsb pdb:5PRS|rcsb pdb:5PRT|rcsb pdb:5PRU|rcsb pdb:5PRV|rcsb pdb:5PRW|rcsb pdb:5PRX|rcsb pdb:5PRY|rcsb pdb:5PRZ|rcsb pdb:5PS0|rcsb pdb:5PS1|rcsb pdb:5PS2|rcsb pdb:5PS3|rcsb pdb:5PS4|rcsb pdb:5PS5|rcsb pdb:5PS6|rcsb pdb:5PS7|rcsb pdb:5PS8|rcsb pdb:5PS9|rcsb pdb:5PSA|rcsb pdb:5PSB|rcsb pdb:5PSC|rcsb pdb:5PSD|rcsb pdb:5PSE|rcsb pdb:5PSF|rcsb pdb:5PSG|rcsb pdb:5PSH|rcsb pdb:5PSI|rcsb pdb:5PSJ|rcsb pdb:5PSK|rcsb pdb:5PSL|rcsb pdb:5PSM|rcsb pdb:5PSN|rcsb pdb:5PSO|rcsb pdb:5PSP|rcsb pdb:5PSQ|rcsb pdb:5PSR|rcsb pdb:5PSS|rcsb pdb:5PSU|rcsb pdb:5PSV|rcsb pdb:5PSW|rcsb pdb:5PSX|rcsb pdb:5PSY|rcsb pdb:5PSZ|rcsb pdb:5PT0|rcsb pdb:5PT1|rcsb pdb:5PT2|rcsb pdb:5PT3|rcsb pdb:5PT4|rcsb pdb:5PT5|rcsb pdb:5PT6|rcsb pdb:5PT7|rcsb pdb:5PT8|rcsb pdb:5PT9|rcsb pdb:5PTA|rcsb pdb:5PTB|rcsb pdb:5PTC|rcsb pdb:5PTE|rcsb pdb:5PTF|rcsb pdb:5PTG|rcsb pdb:5PTH|rcsb pdb:5PTJ|rcsb pdb:5PTK|rcsb pdb:5PTL|rcsb pdb:5PTM|rcsb pdb:5PTN|rcsb pdb:5PTO|rcsb pdb:5PTQ|rcsb pdb:5PTR|rcsb pdb:5PTS|rcsb pdb:5PTT|rcsb pdb:5PTU|rcsb pdb:5PTV|rcsb pdb:5PTW|rcsb pdb:5PTX|rcsb pdb:5PTY|rcsb pdb:5PTZ|rcsb pdb:5PU0|rcsb pdb:5PU1|rcsb pdb:5PU2|rcsb pdb:5PU3|rcsb pdb:5PU4|rcsb pdb:5PU5|rcsb pdb:5PU6|rcsb pdb:5PU7|rcsb pdb:5PU8|rcsb pdb:5PU9|rcsb pdb:5PUA|rcsb pdb:5PUB|rcsb pdb:5PUC|rcsb pdb:5PUD|rcsb pdb:5PUE|rcsb pdb:5PUF|rcsb pdb:5PUG|rcsb pdb:5PUH|rcsb pdb:5PUI|rcsb pdb:5PUJ|rcsb pdb:5PUK|rcsb pdb:5PUL|rcsb pdb:5PUM|rcsb pdb:5PUN|rcsb pdb:5PUO|rcsb pdb:5PUP|rcsb pdb:5PUQ|rcsb pdb:5PUR|rcsb pdb:5PUS|rcsb pdb:5PUT|rcsb pdb:5PUU|rcsb pdb:5PUV|rcsb pdb:5PUW|rcsb pdb:5PUX|rcsb pdb:5PUY|rcsb pdb:5PUZ|rcsb pdb:5PV0|rcsb pdb:5PV1|rcsb pdb:5PV2|rcsb pdb:5PV3|rcsb pdb:5PV4|rcsb pdb:5PV5|rcsb pdb:5PV6|rcsb pdb:5PV7|rcsb pdb:5PV8|rcsb pdb:5PV9|rcsb pdb:5PVA|rcsb pdb:5PVB|rcsb pdb:5PVC|rcsb pdb:5PVD|rcsb pdb:5PVE|rcsb pdb:5PVF|rcsb pdb:5PVG|rcsb pdb:5PVH|rcsb pdb:5PVI|rcsb pdb:5PVJ|rcsb pdb:5PVK|rcsb pdb:5PVL|rcsb pdb:5PVM|rcsb pdb:5PVN|rcsb pdb:5PVO|rcsb pdb:5PVP|rcsb pdb:5PVQ|rcsb pdb:5PVR|rcsb pdb:5PVS|rcsb pdb:5PVT|rcsb pdb:5PVU|rcsb pdb:5PVV|rcsb pdb:5PVW|rcsb pdb:5PVX|rcsb pdb:5PVY|rcsb pdb:5PVZ|rcsb pdb:5PW0|rcsb pdb:5PW1|rcsb pdb:5PW2|rcsb pdb:5PW3|rcsb pdb:5PW4|rcsb pdb:5PW5|rcsb pdb:5PW6|rcsb pdb:5PW7|rcsb pdb:5PW8|rcsb pdb:5PW9|rcsb pdb:5PWA|rcsb pdb:5PWB|rcsb pdb:6IN2|rcsb pdb:6MAJ|rcsb pdb:6MAK|rcsb pdb:7LH9|reactome:R-HSA-3214847|reactome:R-HSA-6804758|refseq:NP_001291737.1|refseq:NP_001291738.1|refseq:XP_016884204.1|refseq:XP_016884205.1 refseq:NP_036611.2|ensembl:ENSG00000170027(gene)|ensembl:ENST00000307630(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006605"(protein targeting)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P61981|rcsb pdb:2B05|rcsb pdb:3UZD|rcsb pdb:4E2E|rcsb pdb:4J6S|rcsb pdb:4O46|rcsb pdb:5D3E|rcsb pdb:6A5S|rcsb pdb:6BYJ|rcsb pdb:6BYL|rcsb pdb:6BZD|rcsb pdb:6FEL|rcsb pdb:6GKF|rcsb pdb:6GKG|rcsb pdb:6S9K|rcsb pdb:6SAD|rcsb pdb:6Y4K|rcsb pdb:6Y6B|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-9614399|dip:DIP-33406N - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:P/L2yjwT2CYr7rO64cYcdahm2z09606 rogid:u1cd71h0RPgTOEMrQVhOelsxWnM9606 rigid:61ptXJ352/6k7OWcQc+mQW/uIAg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95696 uniprotkb:Q99417 intact:EBI-714754|uniprotkb:A6ZJA4|ensembl:ENSP00000216267|ensembl:ENSP00000384076 intact:EBI-716185|intact:EBI-2559925|uniprotkb:Q5TA64|uniprotkb:Q96HE2|uniprotkb:B2R4N0|ensembl:ENSP00000380702 psi-mi:brd1_human(display_long)|uniprotkb:BR140-like protein(gene name synonym)|uniprotkb:BRD1(gene name)|psi-mi:BRD1(display_short)|uniprotkb:BRL(gene name synonym)|uniprotkb:BRPF2(gene name synonym)|uniprotkb:Bromodomain and PHD finger-containing protein 2(gene name synonym) psi-mi:mycbp_human(display_long)|uniprotkb:Associate of Myc 1(gene name synonym)|uniprotkb:MYCBP(gene name)|psi-mi:MYCBP(display_short)|uniprotkb:AMY1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476670|imex:IM-26985-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0036409"(histone H3-K14 acetyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051602"(response to electrical stimulus)|ensembl:ENSG00000100425(gene)|ensembl:ENST00000216267(transcript)|ensembl:ENST00000404034(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0016607"(nuclear speck)|go:"GO:0030425"(dendrite)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042004|interpro:IPR042009|mint:O95696|rcsb pdb:2KU3|rcsb pdb:2L43|rcsb pdb:2LQ6|rcsb pdb:3LYI|rcsb pdb:3RCW|rcsb pdb:4Z02|rcsb pdb:5AME|rcsb pdb:5AMF|rcsb pdb:5FG6|rcsb pdb:5GK9|rcsb pdb:5N49|rcsb pdb:5PNX|rcsb pdb:5PNY|rcsb pdb:5PNZ|rcsb pdb:5PO0|rcsb pdb:5PO1|rcsb pdb:5PO2|rcsb pdb:5PO3|rcsb pdb:5PO4|rcsb pdb:5PO5|rcsb pdb:5PO6|rcsb pdb:5PO7|rcsb pdb:5PO8|rcsb pdb:5PO9|rcsb pdb:5POA|rcsb pdb:5POB|rcsb pdb:5POC|rcsb pdb:5POD|rcsb pdb:5POE|rcsb pdb:5POF|rcsb pdb:5POG|rcsb pdb:5POH|rcsb pdb:5POI|rcsb pdb:5POJ|rcsb pdb:5POK|rcsb pdb:5POL|rcsb pdb:5POM|rcsb pdb:5PON|rcsb pdb:5POO|rcsb pdb:5POP|rcsb pdb:5POQ|refseq:XP_016884206.1|rcsb pdb:5POR|rcsb pdb:5POS|rcsb pdb:5POT|rcsb pdb:5POU|rcsb pdb:5POV|rcsb pdb:5POW|rcsb pdb:5POX|rcsb pdb:5POY|rcsb pdb:5POZ|rcsb pdb:5PP0|rcsb pdb:5PP1|rcsb pdb:5PP2|rcsb pdb:5PP3|rcsb pdb:5PP4|rcsb pdb:5PP5|rcsb pdb:5PP6|rcsb pdb:5PP7|rcsb pdb:5PP8|rcsb pdb:5PP9|rcsb pdb:5PPA|rcsb pdb:5PPB|rcsb pdb:5PPC|rcsb pdb:5PPD|rcsb pdb:5PPE|rcsb pdb:5PPF|rcsb pdb:5PPG|rcsb pdb:5PPH|rcsb pdb:5PPI|rcsb pdb:5PPJ|rcsb pdb:5PPK|rcsb pdb:5PPL|rcsb pdb:5PPM|rcsb pdb:5PPN|rcsb pdb:5PPO|rcsb pdb:5PPP|rcsb pdb:5PPQ|rcsb pdb:5PPR|rcsb pdb:5PPS|rcsb pdb:5PPT|rcsb pdb:5PPU|rcsb pdb:5PPV|rcsb pdb:5PPW|rcsb pdb:5PPX|rcsb pdb:5PPY|rcsb pdb:5PPZ|rcsb pdb:5PQ0|rcsb pdb:5PQ1|rcsb pdb:5PQ2|rcsb pdb:5PQ3|rcsb pdb:5PQ4|rcsb pdb:5PQ5|rcsb pdb:5PQ6|rcsb pdb:5PQ7|rcsb pdb:5PQ8|rcsb pdb:5PQ9|rcsb pdb:5PQA|rcsb pdb:5PQB|rcsb pdb:5PQC|rcsb pdb:5PQD|rcsb pdb:5PQE|rcsb pdb:5PQF|rcsb pdb:5PQG|rcsb pdb:5PQH|rcsb pdb:5PQI|rcsb pdb:5PQJ|rcsb pdb:5PQK|rcsb pdb:5PQL|rcsb pdb:5PQM|rcsb pdb:5PQN|rcsb pdb:5PQO|rcsb pdb:5PQP|rcsb pdb:5PQQ|rcsb pdb:5PQR|rcsb pdb:5PQS|rcsb pdb:5PQT|rcsb pdb:5PQU|rcsb pdb:5PQV|rcsb pdb:5PQW|rcsb pdb:5PQX|rcsb pdb:5PQY|rcsb pdb:5PQZ|rcsb pdb:5PR0|rcsb pdb:5PR1|rcsb pdb:5PR2|rcsb pdb:5PR4|rcsb pdb:5PR5|rcsb pdb:5PR6|rcsb pdb:5PR7|rcsb pdb:5PR8|rcsb pdb:5PST|rcsb pdb:5PR9|rcsb pdb:5PRA|rcsb pdb:5PRB|rcsb pdb:5PRD|rcsb pdb:5PRE|rcsb pdb:5PRF|rcsb pdb:5PRG|rcsb pdb:5PRH|rcsb pdb:5PRI|rcsb pdb:5PRJ|rcsb pdb:5PRK|rcsb pdb:5PRL|rcsb pdb:5PRM|rcsb pdb:5PRO|rcsb pdb:5PRP|rcsb pdb:5PRQ|rcsb pdb:5PRR|rcsb pdb:5PRS|rcsb pdb:5PRT|rcsb pdb:5PRU|rcsb pdb:5PRV|rcsb pdb:5PRW|rcsb pdb:5PRX|rcsb pdb:5PRY|rcsb pdb:5PRZ|rcsb pdb:5PS0|rcsb pdb:5PS1|rcsb pdb:5PS2|rcsb pdb:5PS3|rcsb pdb:5PS4|rcsb pdb:5PS5|rcsb pdb:5PS6|rcsb pdb:5PS7|rcsb pdb:5PS8|rcsb pdb:5PS9|rcsb pdb:5PSA|rcsb pdb:5PSB|rcsb pdb:5PSC|rcsb pdb:5PSD|rcsb pdb:5PSE|rcsb pdb:5PSF|rcsb pdb:5PSG|rcsb pdb:5PSH|rcsb pdb:5PSI|rcsb pdb:5PSJ|rcsb pdb:5PSK|rcsb pdb:5PSL|rcsb pdb:5PSM|rcsb pdb:5PSN|rcsb pdb:5PSO|rcsb pdb:5PSP|rcsb pdb:5PSQ|rcsb pdb:5PSR|rcsb pdb:5PSS|rcsb pdb:5PSU|rcsb pdb:5PSV|rcsb pdb:5PSW|rcsb pdb:5PSX|rcsb pdb:5PSY|rcsb pdb:5PSZ|rcsb pdb:5PT0|rcsb pdb:5PT1|rcsb pdb:5PT2|rcsb pdb:5PT3|rcsb pdb:5PT4|rcsb pdb:5PT5|rcsb pdb:5PT6|rcsb pdb:5PT7|rcsb pdb:5PT8|rcsb pdb:5PT9|rcsb pdb:5PTA|rcsb pdb:5PTB|rcsb pdb:5PTC|rcsb pdb:5PTE|rcsb pdb:5PTF|rcsb pdb:5PTG|rcsb pdb:5PTH|rcsb pdb:5PTJ|rcsb pdb:5PTK|rcsb pdb:5PTL|rcsb pdb:5PTM|rcsb pdb:5PTN|rcsb pdb:5PTO|rcsb pdb:5PTQ|rcsb pdb:5PTR|rcsb pdb:5PTS|rcsb pdb:5PTT|rcsb pdb:5PTU|rcsb pdb:5PTV|rcsb pdb:5PTW|rcsb pdb:5PTX|rcsb pdb:5PTY|rcsb pdb:5PTZ|rcsb pdb:5PU0|rcsb pdb:5PU1|rcsb pdb:5PU2|rcsb pdb:5PU3|rcsb pdb:5PU4|rcsb pdb:5PU5|rcsb pdb:5PU6|rcsb pdb:5PU7|rcsb pdb:5PU8|rcsb pdb:5PU9|rcsb pdb:5PUA|rcsb pdb:5PUB|rcsb pdb:5PUC|rcsb pdb:5PUD|rcsb pdb:5PUE|rcsb pdb:5PUF|rcsb pdb:5PUG|rcsb pdb:5PUH|rcsb pdb:5PUI|rcsb pdb:5PUJ|rcsb pdb:5PUK|rcsb pdb:5PUL|rcsb pdb:5PUM|rcsb pdb:5PUN|rcsb pdb:5PUO|rcsb pdb:5PUP|rcsb pdb:5PUQ|rcsb pdb:5PUR|rcsb pdb:5PUS|rcsb pdb:5PUT|rcsb pdb:5PUU|rcsb pdb:5PUV|rcsb pdb:5PUW|rcsb pdb:5PUX|rcsb pdb:5PUY|rcsb pdb:5PUZ|rcsb pdb:5PV0|rcsb pdb:5PV1|rcsb pdb:5PV2|rcsb pdb:5PV3|rcsb pdb:5PV4|rcsb pdb:5PV5|rcsb pdb:5PV6|rcsb pdb:5PV7|rcsb pdb:5PV8|rcsb pdb:5PV9|rcsb pdb:5PVA|rcsb pdb:5PVB|rcsb pdb:5PVC|rcsb pdb:5PVD|rcsb pdb:5PVE|rcsb pdb:5PVF|rcsb pdb:5PVG|rcsb pdb:5PVH|rcsb pdb:5PVI|rcsb pdb:5PVJ|rcsb pdb:5PVK|rcsb pdb:5PVL|rcsb pdb:5PVM|rcsb pdb:5PVN|rcsb pdb:5PVO|rcsb pdb:5PVP|rcsb pdb:5PVQ|rcsb pdb:5PVR|rcsb pdb:5PVS|rcsb pdb:5PVT|rcsb pdb:5PVU|rcsb pdb:5PVV|rcsb pdb:5PVW|rcsb pdb:5PVX|rcsb pdb:5PVY|rcsb pdb:5PVZ|rcsb pdb:5PW0|rcsb pdb:5PW1|rcsb pdb:5PW2|rcsb pdb:5PW3|rcsb pdb:5PW4|rcsb pdb:5PW5|rcsb pdb:5PW6|rcsb pdb:5PW7|rcsb pdb:5PW8|rcsb pdb:5PW9|rcsb pdb:5PWA|rcsb pdb:5PWB|rcsb pdb:6IN2|rcsb pdb:6MAJ|rcsb pdb:6MAK|rcsb pdb:7LH9|reactome:R-HSA-3214847|reactome:R-HSA-6804758|refseq:NP_001291737.1|refseq:NP_001291738.1|refseq:XP_016884204.1|refseq:XP_016884205.1 refseq:NP_036465.2|ensembl:ENSG00000214114(gene)|ensembl:ENST00000397572(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007283"(spermatogenesis)|interpro:IPR026060|mint:Q99417|rcsb pdb:2YY0 - - comment:"author score: 33" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:P/L2yjwT2CYr7rO64cYcdahm2z09606 rogid:jIStn1A10DDkgTuwVeKpDPJ6tIs9606 rigid:61ptXJ352/6k7OWcQc+mQW/uIAg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95696 uniprotkb:P62633 intact:EBI-714754|uniprotkb:A6ZJA4|ensembl:ENSP00000216267|ensembl:ENSP00000384076 intact:EBI-1047529|uniprotkb:D3DNB9|uniprotkb:D3DNC0|uniprotkb:D3DNC1|uniprotkb:P20694|uniprotkb:Q5QJR0|uniprotkb:Q6PJI7|uniprotkb:Q96NV3|uniprotkb:B4DP17|uniprotkb:Q4JGY1|uniprotkb:B2RAV9|uniprotkb:Q4JGY0|uniprotkb:Q5U0E9|ensembl:ENSP00000410619|uniprotkb:A8K7V4|uniprotkb:E9PDR7 psi-mi:brd1_human(display_long)|uniprotkb:BR140-like protein(gene name synonym)|uniprotkb:BRD1(gene name)|psi-mi:BRD1(display_short)|uniprotkb:BRL(gene name synonym)|uniprotkb:BRPF2(gene name synonym)|uniprotkb:Bromodomain and PHD finger-containing protein 2(gene name synonym) psi-mi:cnbp_human(display_long)|uniprotkb:Zinc finger protein 9(gene name synonym)|uniprotkb:CNBP(gene name)|psi-mi:CNBP(display_short)|uniprotkb:ZNF9(gene name synonym)|uniprotkb:RNF163(gene name synonym)|uniprotkb:Cellular nucleic acid-binding protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476670|imex:IM-26985-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0036409"(histone H3-K14 acetyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051602"(response to electrical stimulus)|ensembl:ENSG00000100425(gene)|ensembl:ENST00000216267(transcript)|ensembl:ENST00000404034(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0016607"(nuclear speck)|go:"GO:0030425"(dendrite)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042004|interpro:IPR042009|mint:O95696|rcsb pdb:2KU3|rcsb pdb:2L43|rcsb pdb:2LQ6|rcsb pdb:3LYI|rcsb pdb:3RCW|rcsb pdb:4Z02|rcsb pdb:5AME|rcsb pdb:5AMF|rcsb pdb:5FG6|rcsb pdb:5GK9|rcsb pdb:5N49|rcsb pdb:5PNX|rcsb pdb:5PNY|rcsb pdb:5PNZ|rcsb pdb:5PO0|rcsb pdb:5PO1|rcsb pdb:5PO2|rcsb pdb:5PO3|rcsb pdb:5PO4|rcsb pdb:5PO5|rcsb pdb:5PO6|rcsb pdb:5PO7|rcsb pdb:5PO8|rcsb pdb:5PO9|rcsb pdb:5POA|rcsb pdb:5POB|rcsb pdb:5POC|rcsb pdb:5POD|rcsb pdb:5POE|rcsb pdb:5POF|rcsb pdb:5POG|rcsb pdb:5POH|rcsb pdb:5POI|rcsb pdb:5POJ|rcsb pdb:5POK|rcsb pdb:5POL|rcsb pdb:5POM|rcsb pdb:5PON|rcsb pdb:5POO|rcsb pdb:5POP|rcsb pdb:5POQ|refseq:XP_016884206.1|rcsb pdb:5POR|rcsb pdb:5POS|rcsb pdb:5POT|rcsb pdb:5POU|rcsb pdb:5POV|rcsb pdb:5POW|rcsb pdb:5POX|rcsb pdb:5POY|rcsb pdb:5POZ|rcsb pdb:5PP0|rcsb pdb:5PP1|rcsb pdb:5PP2|rcsb pdb:5PP3|rcsb pdb:5PP4|rcsb pdb:5PP5|rcsb pdb:5PP6|rcsb pdb:5PP7|rcsb pdb:5PP8|rcsb pdb:5PP9|rcsb pdb:5PPA|rcsb pdb:5PPB|rcsb pdb:5PPC|rcsb pdb:5PPD|rcsb pdb:5PPE|rcsb pdb:5PPF|rcsb pdb:5PPG|rcsb pdb:5PPH|rcsb pdb:5PPI|rcsb pdb:5PPJ|rcsb pdb:5PPK|rcsb pdb:5PPL|rcsb pdb:5PPM|rcsb pdb:5PPN|rcsb pdb:5PPO|rcsb pdb:5PPP|rcsb pdb:5PPQ|rcsb pdb:5PPR|rcsb pdb:5PPS|rcsb pdb:5PPT|rcsb pdb:5PPU|rcsb pdb:5PPV|rcsb pdb:5PPW|rcsb pdb:5PPX|rcsb pdb:5PPY|rcsb pdb:5PPZ|rcsb pdb:5PQ0|rcsb pdb:5PQ1|rcsb pdb:5PQ2|rcsb pdb:5PQ3|rcsb pdb:5PQ4|rcsb pdb:5PQ5|rcsb pdb:5PQ6|rcsb pdb:5PQ7|rcsb pdb:5PQ8|rcsb pdb:5PQ9|rcsb pdb:5PQA|rcsb pdb:5PQB|rcsb pdb:5PQC|rcsb pdb:5PQD|rcsb pdb:5PQE|rcsb pdb:5PQF|rcsb pdb:5PQG|rcsb pdb:5PQH|rcsb pdb:5PQI|rcsb pdb:5PQJ|rcsb pdb:5PQK|rcsb pdb:5PQL|rcsb pdb:5PQM|rcsb pdb:5PQN|rcsb pdb:5PQO|rcsb pdb:5PQP|rcsb pdb:5PQQ|rcsb pdb:5PQR|rcsb pdb:5PQS|rcsb pdb:5PQT|rcsb pdb:5PQU|rcsb pdb:5PQV|rcsb pdb:5PQW|rcsb pdb:5PQX|rcsb pdb:5PQY|rcsb pdb:5PQZ|rcsb pdb:5PR0|rcsb pdb:5PR1|rcsb pdb:5PR2|rcsb pdb:5PR4|rcsb pdb:5PR5|rcsb pdb:5PR6|rcsb pdb:5PR7|rcsb pdb:5PR8|rcsb pdb:5PST|rcsb pdb:5PR9|rcsb pdb:5PRA|rcsb pdb:5PRB|rcsb pdb:5PRD|rcsb pdb:5PRE|rcsb pdb:5PRF|rcsb pdb:5PRG|rcsb pdb:5PRH|rcsb pdb:5PRI|rcsb pdb:5PRJ|rcsb pdb:5PRK|rcsb pdb:5PRL|rcsb pdb:5PRM|rcsb pdb:5PRO|rcsb pdb:5PRP|rcsb pdb:5PRQ|rcsb pdb:5PRR|rcsb pdb:5PRS|rcsb pdb:5PRT|rcsb pdb:5PRU|rcsb pdb:5PRV|rcsb pdb:5PRW|rcsb pdb:5PRX|rcsb pdb:5PRY|rcsb pdb:5PRZ|rcsb pdb:5PS0|rcsb pdb:5PS1|rcsb pdb:5PS2|rcsb pdb:5PS3|rcsb pdb:5PS4|rcsb pdb:5PS5|rcsb pdb:5PS6|rcsb pdb:5PS7|rcsb pdb:5PS8|rcsb pdb:5PS9|rcsb pdb:5PSA|rcsb pdb:5PSB|rcsb pdb:5PSC|rcsb pdb:5PSD|rcsb pdb:5PSE|rcsb pdb:5PSF|rcsb pdb:5PSG|rcsb pdb:5PSH|rcsb pdb:5PSI|rcsb pdb:5PSJ|rcsb pdb:5PSK|rcsb pdb:5PSL|rcsb pdb:5PSM|rcsb pdb:5PSN|rcsb pdb:5PSO|rcsb pdb:5PSP|rcsb pdb:5PSQ|rcsb pdb:5PSR|rcsb pdb:5PSS|rcsb pdb:5PSU|rcsb pdb:5PSV|rcsb pdb:5PSW|rcsb pdb:5PSX|rcsb pdb:5PSY|rcsb pdb:5PSZ|rcsb pdb:5PT0|rcsb pdb:5PT1|rcsb pdb:5PT2|rcsb pdb:5PT3|rcsb pdb:5PT4|rcsb pdb:5PT5|rcsb pdb:5PT6|rcsb pdb:5PT7|rcsb pdb:5PT8|rcsb pdb:5PT9|rcsb pdb:5PTA|rcsb pdb:5PTB|rcsb pdb:5PTC|rcsb pdb:5PTE|rcsb pdb:5PTF|rcsb pdb:5PTG|rcsb pdb:5PTH|rcsb pdb:5PTJ|rcsb pdb:5PTK|rcsb pdb:5PTL|rcsb pdb:5PTM|rcsb pdb:5PTN|rcsb pdb:5PTO|rcsb pdb:5PTQ|rcsb pdb:5PTR|rcsb pdb:5PTS|rcsb pdb:5PTT|rcsb pdb:5PTU|rcsb pdb:5PTV|rcsb pdb:5PTW|rcsb pdb:5PTX|rcsb pdb:5PTY|rcsb pdb:5PTZ|rcsb pdb:5PU0|rcsb pdb:5PU1|rcsb pdb:5PU2|rcsb pdb:5PU3|rcsb pdb:5PU4|rcsb pdb:5PU5|rcsb pdb:5PU6|rcsb pdb:5PU7|rcsb pdb:5PU8|rcsb pdb:5PU9|rcsb pdb:5PUA|rcsb pdb:5PUB|rcsb pdb:5PUC|rcsb pdb:5PUD|rcsb pdb:5PUE|rcsb pdb:5PUF|rcsb pdb:5PUG|rcsb pdb:5PUH|rcsb pdb:5PUI|rcsb pdb:5PUJ|rcsb pdb:5PUK|rcsb pdb:5PUL|rcsb pdb:5PUM|rcsb pdb:5PUN|rcsb pdb:5PUO|rcsb pdb:5PUP|rcsb pdb:5PUQ|rcsb pdb:5PUR|rcsb pdb:5PUS|rcsb pdb:5PUT|rcsb pdb:5PUU|rcsb pdb:5PUV|rcsb pdb:5PUW|rcsb pdb:5PUX|rcsb pdb:5PUY|rcsb pdb:5PUZ|rcsb pdb:5PV0|rcsb pdb:5PV1|rcsb pdb:5PV2|rcsb pdb:5PV3|rcsb pdb:5PV4|rcsb pdb:5PV5|rcsb pdb:5PV6|rcsb pdb:5PV7|rcsb pdb:5PV8|rcsb pdb:5PV9|rcsb pdb:5PVA|rcsb pdb:5PVB|rcsb pdb:5PVC|rcsb pdb:5PVD|rcsb pdb:5PVE|rcsb pdb:5PVF|rcsb pdb:5PVG|rcsb pdb:5PVH|rcsb pdb:5PVI|rcsb pdb:5PVJ|rcsb pdb:5PVK|rcsb pdb:5PVL|rcsb pdb:5PVM|rcsb pdb:5PVN|rcsb pdb:5PVO|rcsb pdb:5PVP|rcsb pdb:5PVQ|rcsb pdb:5PVR|rcsb pdb:5PVS|rcsb pdb:5PVT|rcsb pdb:5PVU|rcsb pdb:5PVV|rcsb pdb:5PVW|rcsb pdb:5PVX|rcsb pdb:5PVY|rcsb pdb:5PVZ|rcsb pdb:5PW0|rcsb pdb:5PW1|rcsb pdb:5PW2|rcsb pdb:5PW3|rcsb pdb:5PW4|rcsb pdb:5PW5|rcsb pdb:5PW6|rcsb pdb:5PW7|rcsb pdb:5PW8|rcsb pdb:5PW9|rcsb pdb:5PWA|rcsb pdb:5PWB|rcsb pdb:6IN2|rcsb pdb:6MAJ|rcsb pdb:6MAK|rcsb pdb:7LH9|reactome:R-HSA-3214847|reactome:R-HSA-6804758|refseq:NP_001291737.1|refseq:NP_001291738.1|refseq:XP_016884204.1|refseq:XP_016884205.1 refseq:NP_001120664.1|refseq:NP_001120668.1|refseq:NP_003409.1|refseq:NP_001120665.1|refseq:NP_001120666.1|ensembl:ENSG00000169714(gene)|ensembl:ENST00000422453(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0071919"(G-quadruplex DNA formation)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875|mint:P62633|refseq:NP_001120667.1 - - comment:"author score: 38" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:P/L2yjwT2CYr7rO64cYcdahm2z09606 rogid:x5yqfxy/s3fE/6EmvjrEe7PmanQ9606 rigid:61ptXJ352/6k7OWcQc+mQW/uIAg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95696 uniprotkb:Q9C005 intact:EBI-714754|uniprotkb:A6ZJA4|ensembl:ENSP00000216267|ensembl:ENSP00000384076 intact:EBI-744973|uniprotkb:D6W578|ensembl:ENSP00000295066|ensembl:ENSP00000345837 psi-mi:brd1_human(display_long)|uniprotkb:BR140-like protein(gene name synonym)|uniprotkb:BRD1(gene name)|psi-mi:BRD1(display_short)|uniprotkb:BRL(gene name synonym)|uniprotkb:BRPF2(gene name synonym)|uniprotkb:Bromodomain and PHD finger-containing protein 2(gene name synonym) psi-mi:dpy30_human(display_long)|uniprotkb:DPY30(gene name)|psi-mi:DPY30(display_short)|uniprotkb:Dpy-30-like protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476670|imex:IM-26985-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0036409"(histone H3-K14 acetyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051602"(response to electrical stimulus)|ensembl:ENSG00000100425(gene)|ensembl:ENST00000216267(transcript)|ensembl:ENST00000404034(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0016607"(nuclear speck)|go:"GO:0030425"(dendrite)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042004|interpro:IPR042009|mint:O95696|rcsb pdb:2KU3|rcsb pdb:2L43|rcsb pdb:2LQ6|rcsb pdb:3LYI|rcsb pdb:3RCW|rcsb pdb:4Z02|rcsb pdb:5AME|rcsb pdb:5AMF|rcsb pdb:5FG6|rcsb pdb:5GK9|rcsb pdb:5N49|rcsb pdb:5PNX|rcsb pdb:5PNY|rcsb pdb:5PNZ|rcsb pdb:5PO0|rcsb pdb:5PO1|rcsb pdb:5PO2|rcsb pdb:5PO3|rcsb pdb:5PO4|rcsb pdb:5PO5|rcsb pdb:5PO6|rcsb pdb:5PO7|rcsb pdb:5PO8|rcsb pdb:5PO9|rcsb pdb:5POA|rcsb pdb:5POB|rcsb pdb:5POC|rcsb pdb:5POD|rcsb pdb:5POE|rcsb pdb:5POF|rcsb pdb:5POG|rcsb pdb:5POH|rcsb pdb:5POI|rcsb pdb:5POJ|rcsb pdb:5POK|rcsb pdb:5POL|rcsb pdb:5POM|rcsb pdb:5PON|rcsb pdb:5POO|rcsb pdb:5POP|rcsb pdb:5POQ|refseq:XP_016884206.1|rcsb pdb:5POR|rcsb pdb:5POS|rcsb pdb:5POT|rcsb pdb:5POU|rcsb pdb:5POV|rcsb pdb:5POW|rcsb pdb:5POX|rcsb pdb:5POY|rcsb pdb:5POZ|rcsb pdb:5PP0|rcsb pdb:5PP1|rcsb pdb:5PP2|rcsb pdb:5PP3|rcsb pdb:5PP4|rcsb pdb:5PP5|rcsb pdb:5PP6|rcsb pdb:5PP7|rcsb pdb:5PP8|rcsb pdb:5PP9|rcsb pdb:5PPA|rcsb pdb:5PPB|rcsb pdb:5PPC|rcsb pdb:5PPD|rcsb pdb:5PPE|rcsb pdb:5PPF|rcsb pdb:5PPG|rcsb pdb:5PPH|rcsb pdb:5PPI|rcsb pdb:5PPJ|rcsb pdb:5PPK|rcsb pdb:5PPL|rcsb pdb:5PPM|rcsb pdb:5PPN|rcsb pdb:5PPO|rcsb pdb:5PPP|rcsb pdb:5PPQ|rcsb pdb:5PPR|rcsb pdb:5PPS|rcsb pdb:5PPT|rcsb pdb:5PPU|rcsb pdb:5PPV|rcsb pdb:5PPW|rcsb pdb:5PPX|rcsb pdb:5PPY|rcsb pdb:5PPZ|rcsb pdb:5PQ0|rcsb pdb:5PQ1|rcsb pdb:5PQ2|rcsb pdb:5PQ3|rcsb pdb:5PQ4|rcsb pdb:5PQ5|rcsb pdb:5PQ6|rcsb pdb:5PQ7|rcsb pdb:5PQ8|rcsb pdb:5PQ9|rcsb pdb:5PQA|rcsb pdb:5PQB|rcsb pdb:5PQC|rcsb pdb:5PQD|rcsb pdb:5PQE|rcsb pdb:5PQF|rcsb pdb:5PQG|rcsb pdb:5PQH|rcsb pdb:5PQI|rcsb pdb:5PQJ|rcsb pdb:5PQK|rcsb pdb:5PQL|rcsb pdb:5PQM|rcsb pdb:5PQN|rcsb pdb:5PQO|rcsb pdb:5PQP|rcsb pdb:5PQQ|rcsb pdb:5PQR|rcsb pdb:5PQS|rcsb pdb:5PQT|rcsb pdb:5PQU|rcsb pdb:5PQV|rcsb pdb:5PQW|rcsb pdb:5PQX|rcsb pdb:5PQY|rcsb pdb:5PQZ|rcsb pdb:5PR0|rcsb pdb:5PR1|rcsb pdb:5PR2|rcsb pdb:5PR4|rcsb pdb:5PR5|rcsb pdb:5PR6|rcsb pdb:5PR7|rcsb pdb:5PR8|rcsb pdb:5PST|rcsb pdb:5PR9|rcsb pdb:5PRA|rcsb pdb:5PRB|rcsb pdb:5PRD|rcsb pdb:5PRE|rcsb pdb:5PRF|rcsb pdb:5PRG|rcsb pdb:5PRH|rcsb pdb:5PRI|rcsb pdb:5PRJ|rcsb pdb:5PRK|rcsb pdb:5PRL|rcsb pdb:5PRM|rcsb pdb:5PRO|rcsb pdb:5PRP|rcsb pdb:5PRQ|rcsb pdb:5PRR|rcsb pdb:5PRS|rcsb pdb:5PRT|rcsb pdb:5PRU|rcsb pdb:5PRV|rcsb pdb:5PRW|rcsb pdb:5PRX|rcsb pdb:5PRY|rcsb pdb:5PRZ|rcsb pdb:5PS0|rcsb pdb:5PS1|rcsb pdb:5PS2|rcsb pdb:5PS3|rcsb pdb:5PS4|rcsb pdb:5PS5|rcsb pdb:5PS6|rcsb pdb:5PS7|rcsb pdb:5PS8|rcsb pdb:5PS9|rcsb pdb:5PSA|rcsb pdb:5PSB|rcsb pdb:5PSC|rcsb pdb:5PSD|rcsb pdb:5PSE|rcsb pdb:5PSF|rcsb pdb:5PSG|rcsb pdb:5PSH|rcsb pdb:5PSI|rcsb pdb:5PSJ|rcsb pdb:5PSK|rcsb pdb:5PSL|rcsb pdb:5PSM|rcsb pdb:5PSN|rcsb pdb:5PSO|rcsb pdb:5PSP|rcsb pdb:5PSQ|rcsb pdb:5PSR|rcsb pdb:5PSS|rcsb pdb:5PSU|rcsb pdb:5PSV|rcsb pdb:5PSW|rcsb pdb:5PSX|rcsb pdb:5PSY|rcsb pdb:5PSZ|rcsb pdb:5PT0|rcsb pdb:5PT1|rcsb pdb:5PT2|rcsb pdb:5PT3|rcsb pdb:5PT4|rcsb pdb:5PT5|rcsb pdb:5PT6|rcsb pdb:5PT7|rcsb pdb:5PT8|rcsb pdb:5PT9|rcsb pdb:5PTA|rcsb pdb:5PTB|rcsb pdb:5PTC|rcsb pdb:5PTE|rcsb pdb:5PTF|rcsb pdb:5PTG|rcsb pdb:5PTH|rcsb pdb:5PTJ|rcsb pdb:5PTK|rcsb pdb:5PTL|rcsb pdb:5PTM|rcsb pdb:5PTN|rcsb pdb:5PTO|rcsb pdb:5PTQ|rcsb pdb:5PTR|rcsb pdb:5PTS|rcsb pdb:5PTT|rcsb pdb:5PTU|rcsb pdb:5PTV|rcsb pdb:5PTW|rcsb pdb:5PTX|rcsb pdb:5PTY|rcsb pdb:5PTZ|rcsb pdb:5PU0|rcsb pdb:5PU1|rcsb pdb:5PU2|rcsb pdb:5PU3|rcsb pdb:5PU4|rcsb pdb:5PU5|rcsb pdb:5PU6|rcsb pdb:5PU7|rcsb pdb:5PU8|rcsb pdb:5PU9|rcsb pdb:5PUA|rcsb pdb:5PUB|rcsb pdb:5PUC|rcsb pdb:5PUD|rcsb pdb:5PUE|rcsb pdb:5PUF|rcsb pdb:5PUG|rcsb pdb:5PUH|rcsb pdb:5PUI|rcsb pdb:5PUJ|rcsb pdb:5PUK|rcsb pdb:5PUL|rcsb pdb:5PUM|rcsb pdb:5PUN|rcsb pdb:5PUO|rcsb pdb:5PUP|rcsb pdb:5PUQ|rcsb pdb:5PUR|rcsb pdb:5PUS|rcsb pdb:5PUT|rcsb pdb:5PUU|rcsb pdb:5PUV|rcsb pdb:5PUW|rcsb pdb:5PUX|rcsb pdb:5PUY|rcsb pdb:5PUZ|rcsb pdb:5PV0|rcsb pdb:5PV1|rcsb pdb:5PV2|rcsb pdb:5PV3|rcsb pdb:5PV4|rcsb pdb:5PV5|rcsb pdb:5PV6|rcsb pdb:5PV7|rcsb pdb:5PV8|rcsb pdb:5PV9|rcsb pdb:5PVA|rcsb pdb:5PVB|rcsb pdb:5PVC|rcsb pdb:5PVD|rcsb pdb:5PVE|rcsb pdb:5PVF|rcsb pdb:5PVG|rcsb pdb:5PVH|rcsb pdb:5PVI|rcsb pdb:5PVJ|rcsb pdb:5PVK|rcsb pdb:5PVL|rcsb pdb:5PVM|rcsb pdb:5PVN|rcsb pdb:5PVO|rcsb pdb:5PVP|rcsb pdb:5PVQ|rcsb pdb:5PVR|rcsb pdb:5PVS|rcsb pdb:5PVT|rcsb pdb:5PVU|rcsb pdb:5PVV|rcsb pdb:5PVW|rcsb pdb:5PVX|rcsb pdb:5PVY|rcsb pdb:5PVZ|rcsb pdb:5PW0|rcsb pdb:5PW1|rcsb pdb:5PW2|rcsb pdb:5PW3|rcsb pdb:5PW4|rcsb pdb:5PW5|rcsb pdb:5PW6|rcsb pdb:5PW7|rcsb pdb:5PW8|rcsb pdb:5PW9|rcsb pdb:5PWA|rcsb pdb:5PWB|rcsb pdb:6IN2|rcsb pdb:6MAJ|rcsb pdb:6MAK|rcsb pdb:7LH9|reactome:R-HSA-3214847|reactome:R-HSA-6804758|refseq:NP_001291737.1|refseq:NP_001291738.1|refseq:XP_016884204.1|refseq:XP_016884205.1 refseq:NP_115963.1|ensembl:ENSG00000162961(gene)|ensembl:ENST00000295066(transcript)|ensembl:ENST00000342166(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006348"|go:"GO:0016197"(endosomal transport)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|mint:Q9C005|rcsb pdb:3G36|rcsb pdb:4RIQ|rcsb pdb:4RT4|rcsb pdb:4RTA|rcsb pdb:6E2H|rcsb pdb:6PWV|reactome:R-HSA-3214841|reactome:R-HSA-8936459|refseq:NP_001308138.1|dip:DIP-34476N - - comment:"author score: 43" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:P/L2yjwT2CYr7rO64cYcdahm2z09606 rogid:yC9NJhTfEIT+YyfWRSJLGbRsQkc9606 rigid:61ptXJ352/6k7OWcQc+mQW/uIAg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95696 uniprotkb:Q8WYB5 intact:EBI-714754|uniprotkb:A6ZJA4|ensembl:ENSP00000216267|ensembl:ENSP00000384076 intact:EBI-948029|uniprotkb:O15087|uniprotkb:Q86Y05|uniprotkb:Q8WU81|uniprotkb:Q9UKW2|uniprotkb:Q9UKW3|uniprotkb:Q9UKX0|ensembl:ENSP00000287239|ensembl:ENSP00000486595|ensembl:ENSP00000497166|ensembl:ENSP00000497352|ensembl:ENSP00000497718|ensembl:ENSP00000497841 psi-mi:brd1_human(display_long)|uniprotkb:BR140-like protein(gene name synonym)|uniprotkb:BRD1(gene name)|psi-mi:BRD1(display_short)|uniprotkb:BRL(gene name synonym)|uniprotkb:BRPF2(gene name synonym)|uniprotkb:Bromodomain and PHD finger-containing protein 2(gene name synonym) psi-mi:kat6b_human(display_long)|uniprotkb:MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4(gene name synonym)|uniprotkb:Histone acetyltransferase MOZ2(gene name synonym)|uniprotkb:Monocytic leukemia zinc finger protein-related factor(gene name synonym)|uniprotkb:KAT6B(gene name)|psi-mi:KAT6B(display_short)|uniprotkb:MYST4(gene name synonym)|uniprotkb:KIAA0383(gene name synonym)|uniprotkb:MORF(gene name synonym)|uniprotkb:MOZ2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476670|imex:IM-26985-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0036409"(histone H3-K14 acetyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051602"(response to electrical stimulus)|ensembl:ENSG00000100425(gene)|ensembl:ENST00000216267(transcript)|ensembl:ENST00000404034(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0016607"(nuclear speck)|go:"GO:0030425"(dendrite)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042004|interpro:IPR042009|mint:O95696|rcsb pdb:2KU3|rcsb pdb:2L43|rcsb pdb:2LQ6|rcsb pdb:3LYI|rcsb pdb:3RCW|rcsb pdb:4Z02|rcsb pdb:5AME|rcsb pdb:5AMF|rcsb pdb:5FG6|rcsb pdb:5GK9|rcsb pdb:5N49|rcsb pdb:5PNX|rcsb pdb:5PNY|rcsb pdb:5PNZ|rcsb pdb:5PO0|rcsb pdb:5PO1|rcsb pdb:5PO2|rcsb pdb:5PO3|rcsb pdb:5PO4|rcsb pdb:5PO5|rcsb pdb:5PO6|rcsb pdb:5PO7|rcsb pdb:5PO8|rcsb pdb:5PO9|rcsb pdb:5POA|rcsb pdb:5POB|rcsb pdb:5POC|rcsb pdb:5POD|rcsb pdb:5POE|rcsb pdb:5POF|rcsb pdb:5POG|rcsb pdb:5POH|rcsb pdb:5POI|rcsb pdb:5POJ|rcsb pdb:5POK|rcsb pdb:5POL|rcsb pdb:5POM|rcsb pdb:5PON|rcsb pdb:5POO|rcsb pdb:5POP|rcsb pdb:5POQ|refseq:XP_016884206.1|rcsb pdb:5POR|rcsb pdb:5POS|rcsb pdb:5POT|rcsb pdb:5POU|rcsb pdb:5POV|rcsb pdb:5POW|rcsb pdb:5POX|rcsb pdb:5POY|rcsb pdb:5POZ|rcsb pdb:5PP0|rcsb pdb:5PP1|rcsb pdb:5PP2|rcsb pdb:5PP3|rcsb pdb:5PP4|rcsb pdb:5PP5|rcsb pdb:5PP6|rcsb pdb:5PP7|rcsb pdb:5PP8|rcsb pdb:5PP9|rcsb pdb:5PPA|rcsb pdb:5PPB|rcsb pdb:5PPC|rcsb pdb:5PPD|rcsb pdb:5PPE|rcsb pdb:5PPF|rcsb pdb:5PPG|rcsb pdb:5PPH|rcsb pdb:5PPI|rcsb pdb:5PPJ|rcsb pdb:5PPK|rcsb pdb:5PPL|rcsb pdb:5PPM|rcsb pdb:5PPN|rcsb pdb:5PPO|rcsb pdb:5PPP|rcsb pdb:5PPQ|rcsb pdb:5PPR|rcsb pdb:5PPS|rcsb pdb:5PPT|rcsb pdb:5PPU|rcsb pdb:5PPV|rcsb pdb:5PPW|rcsb pdb:5PPX|rcsb pdb:5PPY|rcsb pdb:5PPZ|rcsb pdb:5PQ0|rcsb pdb:5PQ1|rcsb pdb:5PQ2|rcsb pdb:5PQ3|rcsb pdb:5PQ4|rcsb pdb:5PQ5|rcsb pdb:5PQ6|rcsb pdb:5PQ7|rcsb pdb:5PQ8|rcsb pdb:5PQ9|rcsb pdb:5PQA|rcsb pdb:5PQB|rcsb pdb:5PQC|rcsb pdb:5PQD|rcsb pdb:5PQE|rcsb pdb:5PQF|rcsb pdb:5PQG|rcsb pdb:5PQH|rcsb pdb:5PQI|rcsb pdb:5PQJ|rcsb pdb:5PQK|rcsb pdb:5PQL|rcsb pdb:5PQM|rcsb pdb:5PQN|rcsb pdb:5PQO|rcsb pdb:5PQP|rcsb pdb:5PQQ|rcsb pdb:5PQR|rcsb pdb:5PQS|rcsb pdb:5PQT|rcsb pdb:5PQU|rcsb pdb:5PQV|rcsb pdb:5PQW|rcsb pdb:5PQX|rcsb pdb:5PQY|rcsb pdb:5PQZ|rcsb pdb:5PR0|rcsb pdb:5PR1|rcsb pdb:5PR2|rcsb pdb:5PR4|rcsb pdb:5PR5|rcsb pdb:5PR6|rcsb pdb:5PR7|rcsb pdb:5PR8|rcsb pdb:5PST|rcsb pdb:5PR9|rcsb pdb:5PRA|rcsb pdb:5PRB|rcsb pdb:5PRD|rcsb pdb:5PRE|rcsb pdb:5PRF|rcsb pdb:5PRG|rcsb pdb:5PRH|rcsb pdb:5PRI|rcsb pdb:5PRJ|rcsb pdb:5PRK|rcsb pdb:5PRL|rcsb pdb:5PRM|rcsb pdb:5PRO|rcsb pdb:5PRP|rcsb pdb:5PRQ|rcsb pdb:5PRR|rcsb pdb:5PRS|rcsb pdb:5PRT|rcsb pdb:5PRU|rcsb pdb:5PRV|rcsb pdb:5PRW|rcsb pdb:5PRX|rcsb pdb:5PRY|rcsb pdb:5PRZ|rcsb pdb:5PS0|rcsb pdb:5PS1|rcsb pdb:5PS2|rcsb pdb:5PS3|rcsb pdb:5PS4|rcsb pdb:5PS5|rcsb pdb:5PS6|rcsb pdb:5PS7|rcsb pdb:5PS8|rcsb pdb:5PS9|rcsb pdb:5PSA|rcsb pdb:5PSB|rcsb pdb:5PSC|rcsb pdb:5PSD|rcsb pdb:5PSE|rcsb pdb:5PSF|rcsb pdb:5PSG|rcsb pdb:5PSH|rcsb pdb:5PSI|rcsb pdb:5PSJ|rcsb pdb:5PSK|rcsb pdb:5PSL|rcsb pdb:5PSM|rcsb pdb:5PSN|rcsb pdb:5PSO|rcsb pdb:5PSP|rcsb pdb:5PSQ|rcsb pdb:5PSR|rcsb pdb:5PSS|rcsb pdb:5PSU|rcsb pdb:5PSV|rcsb pdb:5PSW|rcsb pdb:5PSX|rcsb pdb:5PSY|rcsb pdb:5PSZ|rcsb pdb:5PT0|rcsb pdb:5PT1|rcsb pdb:5PT2|rcsb pdb:5PT3|rcsb pdb:5PT4|rcsb pdb:5PT5|rcsb pdb:5PT6|rcsb pdb:5PT7|rcsb pdb:5PT8|rcsb pdb:5PT9|rcsb pdb:5PTA|rcsb pdb:5PTB|rcsb pdb:5PTC|rcsb pdb:5PTE|rcsb pdb:5PTF|rcsb pdb:5PTG|rcsb pdb:5PTH|rcsb pdb:5PTJ|rcsb pdb:5PTK|rcsb pdb:5PTL|rcsb pdb:5PTM|rcsb pdb:5PTN|rcsb pdb:5PTO|rcsb pdb:5PTQ|rcsb pdb:5PTR|rcsb pdb:5PTS|rcsb pdb:5PTT|rcsb pdb:5PTU|rcsb pdb:5PTV|rcsb pdb:5PTW|rcsb pdb:5PTX|rcsb pdb:5PTY|rcsb pdb:5PTZ|rcsb pdb:5PU0|rcsb pdb:5PU1|rcsb pdb:5PU2|rcsb pdb:5PU3|rcsb pdb:5PU4|rcsb pdb:5PU5|rcsb pdb:5PU6|rcsb pdb:5PU7|rcsb pdb:5PU8|rcsb pdb:5PU9|rcsb pdb:5PUA|rcsb pdb:5PUB|rcsb pdb:5PUC|rcsb pdb:5PUD|rcsb pdb:5PUE|rcsb pdb:5PUF|rcsb pdb:5PUG|rcsb pdb:5PUH|rcsb pdb:5PUI|rcsb pdb:5PUJ|rcsb pdb:5PUK|rcsb pdb:5PUL|rcsb pdb:5PUM|rcsb pdb:5PUN|rcsb pdb:5PUO|rcsb pdb:5PUP|rcsb pdb:5PUQ|rcsb pdb:5PUR|rcsb pdb:5PUS|rcsb pdb:5PUT|rcsb pdb:5PUU|rcsb pdb:5PUV|rcsb pdb:5PUW|rcsb pdb:5PUX|rcsb pdb:5PUY|rcsb pdb:5PUZ|rcsb pdb:5PV0|rcsb pdb:5PV1|rcsb pdb:5PV2|rcsb pdb:5PV3|rcsb pdb:5PV4|rcsb pdb:5PV5|rcsb pdb:5PV6|rcsb pdb:5PV7|rcsb pdb:5PV8|rcsb pdb:5PV9|rcsb pdb:5PVA|rcsb pdb:5PVB|rcsb pdb:5PVC|rcsb pdb:5PVD|rcsb pdb:5PVE|rcsb pdb:5PVF|rcsb pdb:5PVG|rcsb pdb:5PVH|rcsb pdb:5PVI|rcsb pdb:5PVJ|rcsb pdb:5PVK|rcsb pdb:5PVL|rcsb pdb:5PVM|rcsb pdb:5PVN|rcsb pdb:5PVO|rcsb pdb:5PVP|rcsb pdb:5PVQ|rcsb pdb:5PVR|rcsb pdb:5PVS|rcsb pdb:5PVT|rcsb pdb:5PVU|rcsb pdb:5PVV|rcsb pdb:5PVW|rcsb pdb:5PVX|rcsb pdb:5PVY|rcsb pdb:5PVZ|rcsb pdb:5PW0|rcsb pdb:5PW1|rcsb pdb:5PW2|rcsb pdb:5PW3|rcsb pdb:5PW4|rcsb pdb:5PW5|rcsb pdb:5PW6|rcsb pdb:5PW7|rcsb pdb:5PW8|rcsb pdb:5PW9|rcsb pdb:5PWA|rcsb pdb:5PWB|rcsb pdb:6IN2|rcsb pdb:6MAJ|rcsb pdb:6MAK|rcsb pdb:7LH9|reactome:R-HSA-3214847|reactome:R-HSA-6804758|refseq:NP_001291737.1|refseq:NP_001291738.1|refseq:XP_016884204.1|refseq:XP_016884205.1 refseq:NP_036462.2|refseq:NP_001243397.1|refseq:NP_001243398.1|refseq:XP_005269721.1|ensembl:ENSP00000287239|ensembl:ENST00000372711|ensembl:ENSP00000361796|ensembl:ENST00000372714|ensembl:ENSP00000361799|ensembl:ENST00000372724|ensembl:ENSP00000361809|ensembl:ENST00000372725|ensembl:ENSP00000361810|ensembl:ENST00000628038|ensembl:ENSP00000485896|ensembl:ENST00000628523|ensembl:ENSP00000487238|ensembl:ENST00000629233|ensembl:ENSP00000487219|ensembl:ENST00000629879|ensembl:ENSP00000486731|ensembl:ENSP00000486595|ensembl:ENSP00000497352|ensembl:ENSP00000497718|ensembl:ENSP00000497841|ensembl:ENST00000648892|ensembl:ENSP00000497048|ensembl:ENST00000649006|ensembl:ENSP00000498139|ensembl:ENSP00000497166|ensembl:ENST00000649574|ensembl:ENSP00000497416|ensembl:ENST00000650575|ensembl:ENSP00000497453|refseq:XP_016871489.1|refseq:XP_016871490.1|refseq:XP_016871491.1|refseq:XP_016871492.1|refseq:XP_016871494.1|refseq:XP_016871495.1|refseq:XP_016871496.1|refseq:XP_016871497.1|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR005818(Histone H1/H5)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR019787|interpro:IPR036388|interpro:IPR036390|interpro:IPR040706|mint:Q8WYB5|interpro:IPR001965(Zinc finger, PHD-type)|rcsb pdb:5U2J|rcsb pdb:6OIE|reactome:R-HSA-3214847|ensembl:ENSG00000281813(gene)|ensembl:ENST00000287239(transcript)|ensembl:ENST00000630001(transcript)|ensembl:ENST00000647630(transcript)|ensembl:ENST00000648605(transcript)|ensembl:ENST00000648725(transcript)|ensembl:ENST00000649463(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|ensembl:ENSG00000156650(gene)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex) - - comment:"author score: 81" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:P/L2yjwT2CYr7rO64cYcdahm2z09606 rogid:SQZ29f1Wqak9s8f4A1mrKmfToU09606 rigid:61ptXJ352/6k7OWcQc+mQW/uIAg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95696 uniprotkb:Q9HAF1 intact:EBI-714754|uniprotkb:A6ZJA4|ensembl:ENSP00000216267|ensembl:ENSP00000384076 intact:EBI-399266|uniprotkb:B1AK64|uniprotkb:Q4F967|uniprotkb:Q7Z311|uniprotkb:Q86WE3|ensembl:ENSP00000296214 psi-mi:brd1_human(display_long)|uniprotkb:BR140-like protein(gene name synonym)|uniprotkb:BRD1(gene name)|psi-mi:BRD1(display_short)|uniprotkb:BRL(gene name synonym)|uniprotkb:BRPF2(gene name synonym)|uniprotkb:Bromodomain and PHD finger-containing protein 2(gene name synonym) psi-mi:eaf6_human(display_long)|uniprotkb:Sarcoma antigen NY-SAR-91(gene name synonym)|uniprotkb:MEAF6(gene name)|psi-mi:MEAF6(display_short)|uniprotkb:EAF6(gene name synonym)|uniprotkb:Esa1-associated factor 6 homolog(gene name synonym)|uniprotkb:C1orf149(gene name synonym)|uniprotkb:CENP-28(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476670|imex:IM-26985-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0036409"(histone H3-K14 acetyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051602"(response to electrical stimulus)|ensembl:ENSG00000100425(gene)|ensembl:ENST00000216267(transcript)|ensembl:ENST00000404034(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0016607"(nuclear speck)|go:"GO:0030425"(dendrite)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042004|interpro:IPR042009|mint:O95696|rcsb pdb:2KU3|rcsb pdb:2L43|rcsb pdb:2LQ6|rcsb pdb:3LYI|rcsb pdb:3RCW|rcsb pdb:4Z02|rcsb pdb:5AME|rcsb pdb:5AMF|rcsb pdb:5FG6|rcsb pdb:5GK9|rcsb pdb:5N49|rcsb pdb:5PNX|rcsb pdb:5PNY|rcsb pdb:5PNZ|rcsb pdb:5PO0|rcsb pdb:5PO1|rcsb pdb:5PO2|rcsb pdb:5PO3|rcsb pdb:5PO4|rcsb pdb:5PO5|rcsb pdb:5PO6|rcsb pdb:5PO7|rcsb pdb:5PO8|rcsb pdb:5PO9|rcsb pdb:5POA|rcsb pdb:5POB|rcsb pdb:5POC|rcsb pdb:5POD|rcsb pdb:5POE|rcsb pdb:5POF|rcsb pdb:5POG|rcsb pdb:5POH|rcsb pdb:5POI|rcsb pdb:5POJ|rcsb pdb:5POK|rcsb pdb:5POL|rcsb pdb:5POM|rcsb pdb:5PON|rcsb pdb:5POO|rcsb pdb:5POP|rcsb pdb:5POQ|refseq:XP_016884206.1|rcsb pdb:5POR|rcsb pdb:5POS|rcsb pdb:5POT|rcsb pdb:5POU|rcsb pdb:5POV|rcsb pdb:5POW|rcsb pdb:5POX|rcsb pdb:5POY|rcsb pdb:5POZ|rcsb pdb:5PP0|rcsb pdb:5PP1|rcsb pdb:5PP2|rcsb pdb:5PP3|rcsb pdb:5PP4|rcsb pdb:5PP5|rcsb pdb:5PP6|rcsb pdb:5PP7|rcsb pdb:5PP8|rcsb pdb:5PP9|rcsb pdb:5PPA|rcsb pdb:5PPB|rcsb pdb:5PPC|rcsb pdb:5PPD|rcsb pdb:5PPE|rcsb pdb:5PPF|rcsb pdb:5PPG|rcsb pdb:5PPH|rcsb pdb:5PPI|rcsb pdb:5PPJ|rcsb pdb:5PPK|rcsb pdb:5PPL|rcsb pdb:5PPM|rcsb pdb:5PPN|rcsb pdb:5PPO|rcsb pdb:5PPP|rcsb pdb:5PPQ|rcsb pdb:5PPR|rcsb pdb:5PPS|rcsb pdb:5PPT|rcsb pdb:5PPU|rcsb pdb:5PPV|rcsb pdb:5PPW|rcsb pdb:5PPX|rcsb pdb:5PPY|rcsb pdb:5PPZ|rcsb pdb:5PQ0|rcsb pdb:5PQ1|rcsb pdb:5PQ2|rcsb pdb:5PQ3|rcsb pdb:5PQ4|rcsb pdb:5PQ5|rcsb pdb:5PQ6|rcsb pdb:5PQ7|rcsb pdb:5PQ8|rcsb pdb:5PQ9|rcsb pdb:5PQA|rcsb pdb:5PQB|rcsb pdb:5PQC|rcsb pdb:5PQD|rcsb pdb:5PQE|rcsb pdb:5PQF|rcsb pdb:5PQG|rcsb pdb:5PQH|rcsb pdb:5PQI|rcsb pdb:5PQJ|rcsb pdb:5PQK|rcsb pdb:5PQL|rcsb pdb:5PQM|rcsb pdb:5PQN|rcsb pdb:5PQO|rcsb pdb:5PQP|rcsb pdb:5PQQ|rcsb pdb:5PQR|rcsb pdb:5PQS|rcsb pdb:5PQT|rcsb pdb:5PQU|rcsb pdb:5PQV|rcsb pdb:5PQW|rcsb pdb:5PQX|rcsb pdb:5PQY|rcsb pdb:5PQZ|rcsb pdb:5PR0|rcsb pdb:5PR1|rcsb pdb:5PR2|rcsb pdb:5PR4|rcsb pdb:5PR5|rcsb pdb:5PR6|rcsb pdb:5PR7|rcsb pdb:5PR8|rcsb pdb:5PST|rcsb pdb:5PR9|rcsb pdb:5PRA|rcsb pdb:5PRB|rcsb pdb:5PRD|rcsb pdb:5PRE|rcsb pdb:5PRF|rcsb pdb:5PRG|rcsb pdb:5PRH|rcsb pdb:5PRI|rcsb pdb:5PRJ|rcsb pdb:5PRK|rcsb pdb:5PRL|rcsb pdb:5PRM|rcsb pdb:5PRO|rcsb pdb:5PRP|rcsb pdb:5PRQ|rcsb pdb:5PRR|rcsb pdb:5PRS|rcsb pdb:5PRT|rcsb pdb:5PRU|rcsb pdb:5PRV|rcsb pdb:5PRW|rcsb pdb:5PRX|rcsb pdb:5PRY|rcsb pdb:5PRZ|rcsb pdb:5PS0|rcsb pdb:5PS1|rcsb pdb:5PS2|rcsb pdb:5PS3|rcsb pdb:5PS4|rcsb pdb:5PS5|rcsb pdb:5PS6|rcsb pdb:5PS7|rcsb pdb:5PS8|rcsb pdb:5PS9|rcsb pdb:5PSA|rcsb pdb:5PSB|rcsb pdb:5PSC|rcsb pdb:5PSD|rcsb pdb:5PSE|rcsb pdb:5PSF|rcsb pdb:5PSG|rcsb pdb:5PSH|rcsb pdb:5PSI|rcsb pdb:5PSJ|rcsb pdb:5PSK|rcsb pdb:5PSL|rcsb pdb:5PSM|rcsb pdb:5PSN|rcsb pdb:5PSO|rcsb pdb:5PSP|rcsb pdb:5PSQ|rcsb pdb:5PSR|rcsb pdb:5PSS|rcsb pdb:5PSU|rcsb pdb:5PSV|rcsb pdb:5PSW|rcsb pdb:5PSX|rcsb pdb:5PSY|rcsb pdb:5PSZ|rcsb pdb:5PT0|rcsb pdb:5PT1|rcsb pdb:5PT2|rcsb pdb:5PT3|rcsb pdb:5PT4|rcsb pdb:5PT5|rcsb pdb:5PT6|rcsb pdb:5PT7|rcsb pdb:5PT8|rcsb pdb:5PT9|rcsb pdb:5PTA|rcsb pdb:5PTB|rcsb pdb:5PTC|rcsb pdb:5PTE|rcsb pdb:5PTF|rcsb pdb:5PTG|rcsb pdb:5PTH|rcsb pdb:5PTJ|rcsb pdb:5PTK|rcsb pdb:5PTL|rcsb pdb:5PTM|rcsb pdb:5PTN|rcsb pdb:5PTO|rcsb pdb:5PTQ|rcsb pdb:5PTR|rcsb pdb:5PTS|rcsb pdb:5PTT|rcsb pdb:5PTU|rcsb pdb:5PTV|rcsb pdb:5PTW|rcsb pdb:5PTX|rcsb pdb:5PTY|rcsb pdb:5PTZ|rcsb pdb:5PU0|rcsb pdb:5PU1|rcsb pdb:5PU2|rcsb pdb:5PU3|rcsb pdb:5PU4|rcsb pdb:5PU5|rcsb pdb:5PU6|rcsb pdb:5PU7|rcsb pdb:5PU8|rcsb pdb:5PU9|rcsb pdb:5PUA|rcsb pdb:5PUB|rcsb pdb:5PUC|rcsb pdb:5PUD|rcsb pdb:5PUE|rcsb pdb:5PUF|rcsb pdb:5PUG|rcsb pdb:5PUH|rcsb pdb:5PUI|rcsb pdb:5PUJ|rcsb pdb:5PUK|rcsb pdb:5PUL|rcsb pdb:5PUM|rcsb pdb:5PUN|rcsb pdb:5PUO|rcsb pdb:5PUP|rcsb pdb:5PUQ|rcsb pdb:5PUR|rcsb pdb:5PUS|rcsb pdb:5PUT|rcsb pdb:5PUU|rcsb pdb:5PUV|rcsb pdb:5PUW|rcsb pdb:5PUX|rcsb pdb:5PUY|rcsb pdb:5PUZ|rcsb pdb:5PV0|rcsb pdb:5PV1|rcsb pdb:5PV2|rcsb pdb:5PV3|rcsb pdb:5PV4|rcsb pdb:5PV5|rcsb pdb:5PV6|rcsb pdb:5PV7|rcsb pdb:5PV8|rcsb pdb:5PV9|rcsb pdb:5PVA|rcsb pdb:5PVB|rcsb pdb:5PVC|rcsb pdb:5PVD|rcsb pdb:5PVE|rcsb pdb:5PVF|rcsb pdb:5PVG|rcsb pdb:5PVH|rcsb pdb:5PVI|rcsb pdb:5PVJ|rcsb pdb:5PVK|rcsb pdb:5PVL|rcsb pdb:5PVM|rcsb pdb:5PVN|rcsb pdb:5PVO|rcsb pdb:5PVP|rcsb pdb:5PVQ|rcsb pdb:5PVR|rcsb pdb:5PVS|rcsb pdb:5PVT|rcsb pdb:5PVU|rcsb pdb:5PVV|rcsb pdb:5PVW|rcsb pdb:5PVX|rcsb pdb:5PVY|rcsb pdb:5PVZ|rcsb pdb:5PW0|rcsb pdb:5PW1|rcsb pdb:5PW2|rcsb pdb:5PW3|rcsb pdb:5PW4|rcsb pdb:5PW5|rcsb pdb:5PW6|rcsb pdb:5PW7|rcsb pdb:5PW8|rcsb pdb:5PW9|rcsb pdb:5PWA|rcsb pdb:5PWB|rcsb pdb:6IN2|rcsb pdb:6MAJ|rcsb pdb:6MAK|rcsb pdb:7LH9|reactome:R-HSA-3214847|reactome:R-HSA-6804758|refseq:NP_001291737.1|refseq:NP_001291738.1|refseq:XP_016884204.1|refseq:XP_016884205.1 refseq:NP_001257804.1|refseq:NP_073593.2|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|go:"GO:1990467"(NuA3a histone acetyltransferase complex)|go:"GO:1990468"(NuA3b histone acetyltransferase complex)|interpro:IPR015418(Histone H4 acetyltransferase, NuA4 complex, Eaf6)|mint:Q9HAF1|reactome:R-HSA-3214847|reactome:R-HSA-6804758|ensembl:ENSG00000163875(gene)|ensembl:ENST00000296214(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|refseq:NP_001257805.1 - - comment:"author score: 194" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:P/L2yjwT2CYr7rO64cYcdahm2z09606 rogid:v0eU3uwnLihcUQhLKYma3WIhofk9606 rigid:61ptXJ352/6k7OWcQc+mQW/uIAg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95696 uniprotkb:O95251 intact:EBI-714754|uniprotkb:A6ZJA4|ensembl:ENSP00000216267|ensembl:ENSP00000384076 intact:EBI-473199|uniprotkb:B3KN74|uniprotkb:B4DFB4|uniprotkb:B4DFE0|uniprotkb:B4DF85|uniprotkb:B4DGY4|uniprotkb:E7ER15|uniprotkb:G5E9K7|intact:EBI-10986821|ensembl:ENSP00000259021 psi-mi:brd1_human(display_long)|uniprotkb:BR140-like protein(gene name synonym)|uniprotkb:BRD1(gene name)|psi-mi:BRD1(display_short)|uniprotkb:BRL(gene name synonym)|uniprotkb:BRPF2(gene name synonym)|uniprotkb:Bromodomain and PHD finger-containing protein 2(gene name synonym) psi-mi:kat7_human(display_long)|uniprotkb:KAT7(gene name)|psi-mi:KAT7(display_short)|uniprotkb:HBO1(gene name synonym)|uniprotkb:HBOa(gene name synonym)|uniprotkb:MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2(gene name synonym)|uniprotkb:Histone acetyltransferase binding to ORC1(gene name synonym)|uniprotkb:MYST2(gene name synonym)|uniprotkb:Lysine acetyltransferase 7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476670|imex:IM-26985-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0036409"(histone H3-K14 acetyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051602"(response to electrical stimulus)|ensembl:ENSG00000100425(gene)|ensembl:ENST00000216267(transcript)|ensembl:ENST00000404034(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0016607"(nuclear speck)|go:"GO:0030425"(dendrite)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042004|interpro:IPR042009|mint:O95696|rcsb pdb:2KU3|rcsb pdb:2L43|rcsb pdb:2LQ6|rcsb pdb:3LYI|rcsb pdb:3RCW|rcsb pdb:4Z02|rcsb pdb:5AME|rcsb pdb:5AMF|rcsb pdb:5FG6|rcsb pdb:5GK9|rcsb pdb:5N49|rcsb pdb:5PNX|rcsb pdb:5PNY|rcsb pdb:5PNZ|rcsb pdb:5PO0|rcsb pdb:5PO1|rcsb pdb:5PO2|rcsb pdb:5PO3|rcsb pdb:5PO4|rcsb pdb:5PO5|rcsb pdb:5PO6|rcsb pdb:5PO7|rcsb pdb:5PO8|rcsb pdb:5PO9|rcsb pdb:5POA|rcsb pdb:5POB|rcsb pdb:5POC|rcsb pdb:5POD|rcsb pdb:5POE|rcsb pdb:5POF|rcsb pdb:5POG|rcsb pdb:5POH|rcsb pdb:5POI|rcsb pdb:5POJ|rcsb pdb:5POK|rcsb pdb:5POL|rcsb pdb:5POM|rcsb pdb:5PON|rcsb pdb:5POO|rcsb pdb:5POP|rcsb pdb:5POQ|refseq:XP_016884206.1|rcsb pdb:5POR|rcsb pdb:5POS|rcsb pdb:5POT|rcsb pdb:5POU|rcsb pdb:5POV|rcsb pdb:5POW|rcsb pdb:5POX|rcsb pdb:5POY|rcsb pdb:5POZ|rcsb pdb:5PP0|rcsb pdb:5PP1|rcsb pdb:5PP2|rcsb pdb:5PP3|rcsb pdb:5PP4|rcsb pdb:5PP5|rcsb pdb:5PP6|rcsb pdb:5PP7|rcsb pdb:5PP8|rcsb pdb:5PP9|rcsb pdb:5PPA|rcsb pdb:5PPB|rcsb pdb:5PPC|rcsb pdb:5PPD|rcsb pdb:5PPE|rcsb pdb:5PPF|rcsb pdb:5PPG|rcsb pdb:5PPH|rcsb pdb:5PPI|rcsb pdb:5PPJ|rcsb pdb:5PPK|rcsb pdb:5PPL|rcsb pdb:5PPM|rcsb pdb:5PPN|rcsb pdb:5PPO|rcsb pdb:5PPP|rcsb pdb:5PPQ|rcsb pdb:5PPR|rcsb pdb:5PPS|rcsb pdb:5PPT|rcsb pdb:5PPU|rcsb pdb:5PPV|rcsb pdb:5PPW|rcsb pdb:5PPX|rcsb pdb:5PPY|rcsb pdb:5PPZ|rcsb pdb:5PQ0|rcsb pdb:5PQ1|rcsb pdb:5PQ2|rcsb pdb:5PQ3|rcsb pdb:5PQ4|rcsb pdb:5PQ5|rcsb pdb:5PQ6|rcsb pdb:5PQ7|rcsb pdb:5PQ8|rcsb pdb:5PQ9|rcsb pdb:5PQA|rcsb pdb:5PQB|rcsb pdb:5PQC|rcsb pdb:5PQD|rcsb pdb:5PQE|rcsb pdb:5PQF|rcsb pdb:5PQG|rcsb pdb:5PQH|rcsb pdb:5PQI|rcsb pdb:5PQJ|rcsb pdb:5PQK|rcsb pdb:5PQL|rcsb pdb:5PQM|rcsb pdb:5PQN|rcsb pdb:5PQO|rcsb pdb:5PQP|rcsb pdb:5PQQ|rcsb pdb:5PQR|rcsb pdb:5PQS|rcsb pdb:5PQT|rcsb pdb:5PQU|rcsb pdb:5PQV|rcsb pdb:5PQW|rcsb pdb:5PQX|rcsb pdb:5PQY|rcsb pdb:5PQZ|rcsb pdb:5PR0|rcsb pdb:5PR1|rcsb pdb:5PR2|rcsb pdb:5PR4|rcsb pdb:5PR5|rcsb pdb:5PR6|rcsb pdb:5PR7|rcsb pdb:5PR8|rcsb pdb:5PST|rcsb pdb:5PR9|rcsb pdb:5PRA|rcsb pdb:5PRB|rcsb pdb:5PRD|rcsb pdb:5PRE|rcsb pdb:5PRF|rcsb pdb:5PRG|rcsb pdb:5PRH|rcsb pdb:5PRI|rcsb pdb:5PRJ|rcsb pdb:5PRK|rcsb pdb:5PRL|rcsb pdb:5PRM|rcsb pdb:5PRO|rcsb pdb:5PRP|rcsb pdb:5PRQ|rcsb pdb:5PRR|rcsb pdb:5PRS|rcsb pdb:5PRT|rcsb pdb:5PRU|rcsb pdb:5PRV|rcsb pdb:5PRW|rcsb pdb:5PRX|rcsb pdb:5PRY|rcsb pdb:5PRZ|rcsb pdb:5PS0|rcsb pdb:5PS1|rcsb pdb:5PS2|rcsb pdb:5PS3|rcsb pdb:5PS4|rcsb pdb:5PS5|rcsb pdb:5PS6|rcsb pdb:5PS7|rcsb pdb:5PS8|rcsb pdb:5PS9|rcsb pdb:5PSA|rcsb pdb:5PSB|rcsb pdb:5PSC|rcsb pdb:5PSD|rcsb pdb:5PSE|rcsb pdb:5PSF|rcsb pdb:5PSG|rcsb pdb:5PSH|rcsb pdb:5PSI|rcsb pdb:5PSJ|rcsb pdb:5PSK|rcsb pdb:5PSL|rcsb pdb:5PSM|rcsb pdb:5PSN|rcsb pdb:5PSO|rcsb pdb:5PSP|rcsb pdb:5PSQ|rcsb pdb:5PSR|rcsb pdb:5PSS|rcsb pdb:5PSU|rcsb pdb:5PSV|rcsb pdb:5PSW|rcsb pdb:5PSX|rcsb pdb:5PSY|rcsb pdb:5PSZ|rcsb pdb:5PT0|rcsb pdb:5PT1|rcsb pdb:5PT2|rcsb pdb:5PT3|rcsb pdb:5PT4|rcsb pdb:5PT5|rcsb pdb:5PT6|rcsb pdb:5PT7|rcsb pdb:5PT8|rcsb pdb:5PT9|rcsb pdb:5PTA|rcsb pdb:5PTB|rcsb pdb:5PTC|rcsb pdb:5PTE|rcsb pdb:5PTF|rcsb pdb:5PTG|rcsb pdb:5PTH|rcsb pdb:5PTJ|rcsb pdb:5PTK|rcsb pdb:5PTL|rcsb pdb:5PTM|rcsb pdb:5PTN|rcsb pdb:5PTO|rcsb pdb:5PTQ|rcsb pdb:5PTR|rcsb pdb:5PTS|rcsb pdb:5PTT|rcsb pdb:5PTU|rcsb pdb:5PTV|rcsb pdb:5PTW|rcsb pdb:5PTX|rcsb pdb:5PTY|rcsb pdb:5PTZ|rcsb pdb:5PU0|rcsb pdb:5PU1|rcsb pdb:5PU2|rcsb pdb:5PU3|rcsb pdb:5PU4|rcsb pdb:5PU5|rcsb pdb:5PU6|rcsb pdb:5PU7|rcsb pdb:5PU8|rcsb pdb:5PU9|rcsb pdb:5PUA|rcsb pdb:5PUB|rcsb pdb:5PUC|rcsb pdb:5PUD|rcsb pdb:5PUE|rcsb pdb:5PUF|rcsb pdb:5PUG|rcsb pdb:5PUH|rcsb pdb:5PUI|rcsb pdb:5PUJ|rcsb pdb:5PUK|rcsb pdb:5PUL|rcsb pdb:5PUM|rcsb pdb:5PUN|rcsb pdb:5PUO|rcsb pdb:5PUP|rcsb pdb:5PUQ|rcsb pdb:5PUR|rcsb pdb:5PUS|rcsb pdb:5PUT|rcsb pdb:5PUU|rcsb pdb:5PUV|rcsb pdb:5PUW|rcsb pdb:5PUX|rcsb pdb:5PUY|rcsb pdb:5PUZ|rcsb pdb:5PV0|rcsb pdb:5PV1|rcsb pdb:5PV2|rcsb pdb:5PV3|rcsb pdb:5PV4|rcsb pdb:5PV5|rcsb pdb:5PV6|rcsb pdb:5PV7|rcsb pdb:5PV8|rcsb pdb:5PV9|rcsb pdb:5PVA|rcsb pdb:5PVB|rcsb pdb:5PVC|rcsb pdb:5PVD|rcsb pdb:5PVE|rcsb pdb:5PVF|rcsb pdb:5PVG|rcsb pdb:5PVH|rcsb pdb:5PVI|rcsb pdb:5PVJ|rcsb pdb:5PVK|rcsb pdb:5PVL|rcsb pdb:5PVM|rcsb pdb:5PVN|rcsb pdb:5PVO|rcsb pdb:5PVP|rcsb pdb:5PVQ|rcsb pdb:5PVR|rcsb pdb:5PVS|rcsb pdb:5PVT|rcsb pdb:5PVU|rcsb pdb:5PVV|rcsb pdb:5PVW|rcsb pdb:5PVX|rcsb pdb:5PVY|rcsb pdb:5PVZ|rcsb pdb:5PW0|rcsb pdb:5PW1|rcsb pdb:5PW2|rcsb pdb:5PW3|rcsb pdb:5PW4|rcsb pdb:5PW5|rcsb pdb:5PW6|rcsb pdb:5PW7|rcsb pdb:5PW8|rcsb pdb:5PW9|rcsb pdb:5PWA|rcsb pdb:5PWB|rcsb pdb:6IN2|rcsb pdb:6MAJ|rcsb pdb:6MAK|rcsb pdb:7LH9|reactome:R-HSA-3214847|reactome:R-HSA-6804758|refseq:NP_001291737.1|refseq:NP_001291738.1|refseq:XP_016884204.1|refseq:XP_016884205.1 refseq:NP_001186084.1|refseq:NP_001186085.1|refseq:NP_001186086.1|refseq:NP_001186087.1|refseq:NP_008998.1|dip:DIP-29697N|ensembl:ENSG00000136504(gene)|ensembl:ENST00000259021(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031098"(stress-activated protein kinase signaling cascade)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0036409"(histone H3-K14 acetyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0072708"(response to sorbitol)|go:"GO:0072710"(response to hydroxyurea)|go:"GO:0072716"(response to actinomycin D)|go:"GO:0072720"(response to dithiothreitol)|go:"GO:0072739"(response to anisomycin)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:0090734"(site of DNA damage)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902035"(positive regulation of hematopoietic stem cell proliferation)|go:"GO:2000819"(regulation of nucleotide-excision repair)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR036060|interpro:IPR036388|interpro:IPR040706|mint:O95251|rcsb pdb:5GK9|rcsb pdb:6MAJ|rcsb pdb:6MAK|reactome:R-HSA-3214847 - - comment:"author score: 197" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:P/L2yjwT2CYr7rO64cYcdahm2z09606 rogid:K27pgvPEe1/+rZXYUkPfMY7PZMs9606 rigid:61ptXJ352/6k7OWcQc+mQW/uIAg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95696 uniprotkb:Q9UNL4 intact:EBI-714754|uniprotkb:A6ZJA4|ensembl:ENSP00000216267|ensembl:ENSP00000384076 intact:EBI-2866661|uniprotkb:Q9H3J0|uniprotkb:Q96E15|uniprotkb:Q4VBQ6|uniprotkb:D3DUR8|uniprotkb:A4KYM4|uniprotkb:Q0EF62|uniprotkb:Q0EF63|uniprotkb:A4KYM6|ensembl:ENSP00000380024 psi-mi:brd1_human(display_long)|uniprotkb:BR140-like protein(gene name synonym)|uniprotkb:BRD1(gene name)|psi-mi:BRD1(display_short)|uniprotkb:BRL(gene name synonym)|uniprotkb:BRPF2(gene name synonym)|uniprotkb:Bromodomain and PHD finger-containing protein 2(gene name synonym) psi-mi:ing4_human(display_long)|uniprotkb:ING4(gene name)|psi-mi:ING4(display_short)|uniprotkb:p29ING4(gene name synonym)|uniprotkb:My036(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476670|imex:IM-26985-65 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0036409"(histone H3-K14 acetyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051602"(response to electrical stimulus)|ensembl:ENSG00000100425(gene)|ensembl:ENST00000216267(transcript)|ensembl:ENST00000404034(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0016607"(nuclear speck)|go:"GO:0030425"(dendrite)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042004|interpro:IPR042009|mint:O95696|rcsb pdb:2KU3|rcsb pdb:2L43|rcsb pdb:2LQ6|rcsb pdb:3LYI|rcsb pdb:3RCW|rcsb pdb:4Z02|rcsb pdb:5AME|rcsb pdb:5AMF|rcsb pdb:5FG6|rcsb pdb:5GK9|rcsb pdb:5N49|rcsb pdb:5PNX|rcsb pdb:5PNY|rcsb pdb:5PNZ|rcsb pdb:5PO0|rcsb pdb:5PO1|rcsb pdb:5PO2|rcsb pdb:5PO3|rcsb pdb:5PO4|rcsb pdb:5PO5|rcsb pdb:5PO6|rcsb pdb:5PO7|rcsb pdb:5PO8|rcsb pdb:5PO9|rcsb pdb:5POA|rcsb pdb:5POB|rcsb pdb:5POC|rcsb pdb:5POD|rcsb pdb:5POE|rcsb pdb:5POF|rcsb pdb:5POG|rcsb pdb:5POH|rcsb pdb:5POI|rcsb pdb:5POJ|rcsb pdb:5POK|rcsb pdb:5POL|rcsb pdb:5POM|rcsb pdb:5PON|rcsb pdb:5POO|rcsb pdb:5POP|rcsb pdb:5POQ|refseq:XP_016884206.1|rcsb pdb:5POR|rcsb pdb:5POS|rcsb pdb:5POT|rcsb pdb:5POU|rcsb pdb:5POV|rcsb pdb:5POW|rcsb pdb:5POX|rcsb pdb:5POY|rcsb pdb:5POZ|rcsb pdb:5PP0|rcsb pdb:5PP1|rcsb pdb:5PP2|rcsb pdb:5PP3|rcsb pdb:5PP4|rcsb pdb:5PP5|rcsb pdb:5PP6|rcsb pdb:5PP7|rcsb pdb:5PP8|rcsb pdb:5PP9|rcsb pdb:5PPA|rcsb pdb:5PPB|rcsb pdb:5PPC|rcsb pdb:5PPD|rcsb pdb:5PPE|rcsb pdb:5PPF|rcsb pdb:5PPG|rcsb pdb:5PPH|rcsb pdb:5PPI|rcsb pdb:5PPJ|rcsb pdb:5PPK|rcsb pdb:5PPL|rcsb pdb:5PPM|rcsb pdb:5PPN|rcsb pdb:5PPO|rcsb pdb:5PPP|rcsb pdb:5PPQ|rcsb pdb:5PPR|rcsb pdb:5PPS|rcsb pdb:5PPT|rcsb pdb:5PPU|rcsb pdb:5PPV|rcsb pdb:5PPW|rcsb pdb:5PPX|rcsb pdb:5PPY|rcsb pdb:5PPZ|rcsb pdb:5PQ0|rcsb pdb:5PQ1|rcsb pdb:5PQ2|rcsb pdb:5PQ3|rcsb pdb:5PQ4|rcsb pdb:5PQ5|rcsb pdb:5PQ6|rcsb pdb:5PQ7|rcsb pdb:5PQ8|rcsb pdb:5PQ9|rcsb pdb:5PQA|rcsb pdb:5PQB|rcsb pdb:5PQC|rcsb pdb:5PQD|rcsb pdb:5PQE|rcsb pdb:5PQF|rcsb pdb:5PQG|rcsb pdb:5PQH|rcsb pdb:5PQI|rcsb pdb:5PQJ|rcsb pdb:5PQK|rcsb pdb:5PQL|rcsb pdb:5PQM|rcsb pdb:5PQN|rcsb pdb:5PQO|rcsb pdb:5PQP|rcsb pdb:5PQQ|rcsb pdb:5PQR|rcsb pdb:5PQS|rcsb pdb:5PQT|rcsb pdb:5PQU|rcsb pdb:5PQV|rcsb pdb:5PQW|rcsb pdb:5PQX|rcsb pdb:5PQY|rcsb pdb:5PQZ|rcsb pdb:5PR0|rcsb pdb:5PR1|rcsb pdb:5PR2|rcsb pdb:5PR4|rcsb pdb:5PR5|rcsb pdb:5PR6|rcsb pdb:5PR7|rcsb pdb:5PR8|rcsb pdb:5PST|rcsb pdb:5PR9|rcsb pdb:5PRA|rcsb pdb:5PRB|rcsb pdb:5PRD|rcsb pdb:5PRE|rcsb pdb:5PRF|rcsb pdb:5PRG|rcsb pdb:5PRH|rcsb pdb:5PRI|rcsb pdb:5PRJ|rcsb pdb:5PRK|rcsb pdb:5PRL|rcsb pdb:5PRM|rcsb pdb:5PRO|rcsb pdb:5PRP|rcsb pdb:5PRQ|rcsb pdb:5PRR|rcsb pdb:5PRS|rcsb pdb:5PRT|rcsb pdb:5PRU|rcsb pdb:5PRV|rcsb pdb:5PRW|rcsb pdb:5PRX|rcsb pdb:5PRY|rcsb pdb:5PRZ|rcsb pdb:5PS0|rcsb pdb:5PS1|rcsb pdb:5PS2|rcsb pdb:5PS3|rcsb pdb:5PS4|rcsb pdb:5PS5|rcsb pdb:5PS6|rcsb pdb:5PS7|rcsb pdb:5PS8|rcsb pdb:5PS9|rcsb pdb:5PSA|rcsb pdb:5PSB|rcsb pdb:5PSC|rcsb pdb:5PSD|rcsb pdb:5PSE|rcsb pdb:5PSF|rcsb pdb:5PSG|rcsb pdb:5PSH|rcsb pdb:5PSI|rcsb pdb:5PSJ|rcsb pdb:5PSK|rcsb pdb:5PSL|rcsb pdb:5PSM|rcsb pdb:5PSN|rcsb pdb:5PSO|rcsb pdb:5PSP|rcsb pdb:5PSQ|rcsb pdb:5PSR|rcsb pdb:5PSS|rcsb pdb:5PSU|rcsb pdb:5PSV|rcsb pdb:5PSW|rcsb pdb:5PSX|rcsb pdb:5PSY|rcsb pdb:5PSZ|rcsb pdb:5PT0|rcsb pdb:5PT1|rcsb pdb:5PT2|rcsb pdb:5PT3|rcsb pdb:5PT4|rcsb pdb:5PT5|rcsb pdb:5PT6|rcsb pdb:5PT7|rcsb pdb:5PT8|rcsb pdb:5PT9|rcsb pdb:5PTA|rcsb pdb:5PTB|rcsb pdb:5PTC|rcsb pdb:5PTE|rcsb pdb:5PTF|rcsb pdb:5PTG|rcsb pdb:5PTH|rcsb pdb:5PTJ|rcsb pdb:5PTK|rcsb pdb:5PTL|rcsb pdb:5PTM|rcsb pdb:5PTN|rcsb pdb:5PTO|rcsb pdb:5PTQ|rcsb pdb:5PTR|rcsb pdb:5PTS|rcsb pdb:5PTT|rcsb pdb:5PTU|rcsb pdb:5PTV|rcsb pdb:5PTW|rcsb pdb:5PTX|rcsb pdb:5PTY|rcsb pdb:5PTZ|rcsb pdb:5PU0|rcsb pdb:5PU1|rcsb pdb:5PU2|rcsb pdb:5PU3|rcsb pdb:5PU4|rcsb pdb:5PU5|rcsb pdb:5PU6|rcsb pdb:5PU7|rcsb pdb:5PU8|rcsb pdb:5PU9|rcsb pdb:5PUA|rcsb pdb:5PUB|rcsb pdb:5PUC|rcsb pdb:5PUD|rcsb pdb:5PUE|rcsb pdb:5PUF|rcsb pdb:5PUG|rcsb pdb:5PUH|rcsb pdb:5PUI|rcsb pdb:5PUJ|rcsb pdb:5PUK|rcsb pdb:5PUL|rcsb pdb:5PUM|rcsb pdb:5PUN|rcsb pdb:5PUO|rcsb pdb:5PUP|rcsb pdb:5PUQ|rcsb pdb:5PUR|rcsb pdb:5PUS|rcsb pdb:5PUT|rcsb pdb:5PUU|rcsb pdb:5PUV|rcsb pdb:5PUW|rcsb pdb:5PUX|rcsb pdb:5PUY|rcsb pdb:5PUZ|rcsb pdb:5PV0|rcsb pdb:5PV1|rcsb pdb:5PV2|rcsb pdb:5PV3|rcsb pdb:5PV4|rcsb pdb:5PV5|rcsb pdb:5PV6|rcsb pdb:5PV7|rcsb pdb:5PV8|rcsb pdb:5PV9|rcsb pdb:5PVA|rcsb pdb:5PVB|rcsb pdb:5PVC|rcsb pdb:5PVD|rcsb pdb:5PVE|rcsb pdb:5PVF|rcsb pdb:5PVG|rcsb pdb:5PVH|rcsb pdb:5PVI|rcsb pdb:5PVJ|rcsb pdb:5PVK|rcsb pdb:5PVL|rcsb pdb:5PVM|rcsb pdb:5PVN|rcsb pdb:5PVO|rcsb pdb:5PVP|rcsb pdb:5PVQ|rcsb pdb:5PVR|rcsb pdb:5PVS|rcsb pdb:5PVT|rcsb pdb:5PVU|rcsb pdb:5PVV|rcsb pdb:5PVW|rcsb pdb:5PVX|rcsb pdb:5PVY|rcsb pdb:5PVZ|rcsb pdb:5PW0|rcsb pdb:5PW1|rcsb pdb:5PW2|rcsb pdb:5PW3|rcsb pdb:5PW4|rcsb pdb:5PW5|rcsb pdb:5PW6|rcsb pdb:5PW7|rcsb pdb:5PW8|rcsb pdb:5PW9|rcsb pdb:5PWA|rcsb pdb:5PWB|rcsb pdb:6IN2|rcsb pdb:6MAJ|rcsb pdb:6MAK|rcsb pdb:7LH9|reactome:R-HSA-3214847|reactome:R-HSA-6804758|refseq:NP_001291737.1|refseq:NP_001291738.1|refseq:XP_016884204.1|refseq:XP_016884205.1 refseq:NP_001121054.1|refseq:NP_001121055.1|refseq:NP_001121056.1|refseq:NP_001121057.1|refseq:NP_001121058.1|refseq:NP_057246.2|dip:DIP-42222N|ensembl:ENSG00000111653(gene)|ensembl:ENST00000396807(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006473"(protein acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|interpro:IPR028651|mint:Q9UNL4|rcsb pdb:2K1J|rcsb pdb:2M1R|rcsb pdb:2PNX|rcsb pdb:2VNF|rcsb pdb:4AFL|reactome:R-HSA-3214847|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028638 - - comment:"author score: 205" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:P/L2yjwT2CYr7rO64cYcdahm2z09606 rogid:71DYqPEISrr06/kbSTCdA3J23NU9606 rigid:61ptXJ352/6k7OWcQc+mQW/uIAg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60885 uniprotkb:P35250 intact:EBI-723869|uniprotkb:O60433|uniprotkb:Q86YS8|uniprotkb:Q96PD3|intact:EBI-28968271|ensembl:ENSP00000263377|ensembl:ENSP00000506350|uniprotkb:Q4G0X8 intact:EBI-476409|uniprotkb:P32846|uniprotkb:Q9BU93|uniprotkb:D3DXG3|ensembl:ENSP00000055077|uniprotkb:B5BU07 psi-mi:brd4_human(display_long)|uniprotkb:Protein HUNK1(gene name synonym)|uniprotkb:BRD4(gene name)|psi-mi:BRD4(display_short)|uniprotkb:HUNK1(gene name synonym) psi-mi:rfc2_human(display_long)|uniprotkb:Activator 1 subunit 2(gene name synonym)|uniprotkb:Replication factor C 40 kDa subunit(gene name synonym)|uniprotkb:Activator 1 40 kDa subunit(gene name synonym)|uniprotkb:RFC2(gene name)|psi-mi:RFC2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476724|imex:IM-26985-307 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055114.1|refseq:NP_490597.1|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|ensembl:ENSG00000141867(gene)|ensembl:ENST00000263377(transcript)|ensembl:ENST00000679869(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0019899"(enzyme binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:1901407"(regulation of phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:2000002"(negative regulation of DNA damage checkpoint)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR001487(Bromodomain)|interpro:IPR018359|interpro:IPR027353|interpro:IPR031354|interpro:IPR036427|interpro:IPR038336|interpro:IPR043508|interpro:IPR043509|mint:O60885|rcsb pdb:2I8N|rcsb pdb:2LSP|rcsb pdb:2MJV|rcsb pdb:2N3K|rcsb pdb:2NCZ|rcsb pdb:2ND0|rcsb pdb:2ND1|rcsb pdb:2NNU|rcsb pdb:2OSS|rcsb pdb:2OUO|rcsb pdb:2YEL|rcsb pdb:2YEM|rcsb pdb:3MXF|rcsb pdb:5Y93|rcsb pdb:5Y94|rcsb pdb:5YOU|rcsb pdb:5YOV|rcsb pdb:5YQX|rcsb pdb:5Z1R|rcsb pdb:5Z1S|rcsb pdb:5Z1T|rcsb pdb:5Z5T|rcsb pdb:5Z5U|rcsb pdb:5Z5V|rcsb pdb:5Z8G|rcsb pdb:5Z8R|rcsb pdb:5Z8Z|rcsb pdb:5Z90|rcsb pdb:5Z9C|rcsb pdb:5Z9K|rcsb pdb:6AFR|rcsb pdb:6AJV|rcsb pdb:6AJW|rcsb pdb:6AJX|rcsb pdb:6AJY|rcsb pdb:6AJZ|rcsb pdb:6BN7|rcsb pdb:6BN8|rcsb pdb:6BN9|rcsb pdb:6BNB|rcsb pdb:6BNH|rcsb pdb:6BOY|rcsb pdb:6C7Q|rcsb pdb:6C7R|rcsb pdb:6CD4|rcsb pdb:6CD5|rcsb pdb:6CIS|rcsb pdb:6CIY|rcsb pdb:6CJ1|rcsb pdb:6CJ2|rcsb pdb:6CKR|rcsb pdb:6CKS|rcsb pdb:6CZU|rcsb pdb:6CZV|rcsb pdb:6DJC|rcsb pdb:6DL2|rcsb pdb:6DMJ|rcsb pdb:6DML|rcsb pdb:6DNE|rcsb pdb:6DUV|rcsb pdb:6FFD|rcsb pdb:6FNX|rcsb pdb:6FO5|rcsb pdb:6E4A|rcsb pdb:6FSY|rcsb pdb:6FT3|rcsb pdb:6FT4|rcsb pdb:6G0D|rcsb pdb:6G0E|rcsb pdb:6G0F|rcsb pdb:6G0G|rcsb pdb:6G0H|rcsb pdb:6G0O|rcsb pdb:6G0P|rcsb pdb:6G0Q|rcsb pdb:6G0R|rcsb pdb:6G0S|rcsb pdb:6HDQ|rcsb pdb:6HOV|rcsb pdb:6I7X|rcsb pdb:6I7Y|rcsb pdb:6IN1|rcsb pdb:6JI3|rcsb pdb:6JI4|rcsb pdb:6JI5|rcsb pdb:6JJ3|rcsb pdb:6JJ5|rcsb pdb:6JJ6|rcsb pdb:6JJB|rcsb pdb:6KEC|rcsb pdb:6KED|rcsb pdb:6KEE|rcsb pdb:6KEF|rcsb pdb:6KEG|rcsb pdb:6KEH|rcsb pdb:6KEI|rcsb pdb:6KEJ|rcsb pdb:6KEK|rcsb pdb:6KO2|rcsb pdb:6SB8|rcsb pdb:6SE4|rcsb pdb:6SIS|rcsb pdb:6LG4|rcsb pdb:6SWN|rcsb pdb:6SWQ|rcsb pdb:6TPX|rcsb pdb:6TPY|rcsb pdb:6TPZ|rcsb pdb:6U0D|rcsb pdb:6U6K|rcsb pdb:6U6L|rcsb pdb:6U72|rcsb pdb:6U74|rcsb pdb:6U8G|rcsb pdb:6U8I|rcsb pdb:6U8M|rcsb pdb:6ULS|rcsb pdb:6ULV|rcsb pdb:6UVJ|rcsb pdb:6UVM|rcsb pdb:6UWU|rcsb pdb:6UWX|rcsb pdb:6V0U|rcsb pdb:6V1K|rcsb pdb:6V1L|rcsb pdb:6V1U|rcsb pdb:3SVF|rcsb pdb:3SVG|rcsb pdb:3U5J|rcsb pdb:3U5K|rcsb pdb:3U5L|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3ZYU|rcsb pdb:4A9L|rcsb pdb:4BJX|rcsb pdb:4BW1|rcsb pdb:4BW2|rcsb pdb:4BW3|rcsb pdb:4BW4|rcsb pdb:4C66|rcsb pdb:4C67|rcsb pdb:3P5O|rcsb pdb:4CFK|rcsb pdb:4CFL|rcsb pdb:4CL9|rcsb pdb:6LG6|rcsb pdb:6LG7|rcsb pdb:6LG8|rcsb pdb:6LG9|rcsb pdb:6LIH|rcsb pdb:6LIM|rcsb pdb:6MAU|rcsb pdb:6MH1|rcsb pdb:6MH7|rcsb pdb:6MNL|rcsb pdb:6P05|rcsb pdb:6PRT|rcsb pdb:6PS9|rcsb pdb:6PSB|rcsb pdb:6Q3Y|rcsb pdb:6LG5|rcsb pdb:6Q3Z|rcsb pdb:6RWJ|rcsb pdb:6S25|rcsb pdb:6S4B|rcsb pdb:6S6K|rcsb pdb:6SA2|rcsb pdb:6SA3|rcsb pdb:6SAH|rcsb pdb:6SAJ|rcsb pdb:4DON|rcsb pdb:4E96|rcsb pdb:4F3I|rcsb pdb:4GPJ|rcsb pdb:4HBV|rcsb pdb:4HBW|rcsb pdb:4HBX|rcsb pdb:4HBY|rcsb pdb:4HXK|rcsb pdb:4HXL|rcsb pdb:4HXM|rcsb pdb:4HXN|rcsb pdb:4HXO|rcsb pdb:4HXP|rcsb pdb:4HXR|rcsb pdb:4HXS|rcsb pdb:4IOO|rcsb pdb:4IOQ|rcsb pdb:4IOR|rcsb pdb:4J0R|rcsb pdb:4J0S|rcsb pdb:4J3I|rcsb pdb:4CLB|rcsb pdb:4KV1|rcsb pdb:4KV4|rcsb pdb:4LR6|rcsb pdb:4LRG|rcsb pdb:4LYI|rcsb pdb:4LYS|rcsb pdb:4LYW|rcsb pdb:4LZR|rcsb pdb:4LZS|rcsb pdb:4MEN|rcsb pdb:4MEO|rcsb pdb:4MEP|rcsb pdb:4MEQ|rcsb pdb:4MR3|rcsb pdb:4MR4|rcsb pdb:4NQM|rcsb pdb:4NR8|rcsb pdb:4NUC|rcsb pdb:4NUD|rcsb pdb:4NUE|rcsb pdb:4O70|rcsb pdb:4O71|rcsb pdb:4O72|rcsb pdb:4O74|rcsb pdb:4O75|rcsb pdb:4O76|rcsb pdb:4O77|rcsb pdb:4O78|rcsb pdb:4O7A|rcsb pdb:4O7B|rcsb pdb:4O7C|rcsb pdb:4O7E|rcsb pdb:4O7F|rcsb pdb:4OGI|rcsb pdb:4OGJ|rcsb pdb:4PCE|rcsb pdb:4PCI|rcsb pdb:4PS5|rcsb pdb:4QR3|rcsb pdb:4QR4|rcsb pdb:4QR5|rcsb pdb:4QZS|rcsb pdb:4UIX|rcsb pdb:4UIY|rcsb pdb:4UIZ|rcsb pdb:4UYD|rcsb pdb:4WHW|rcsb pdb:4WIV|rcsb pdb:4X2I|rcsb pdb:4XY9|rcsb pdb:4XYA|rcsb pdb:4YH3|rcsb pdb:4YH4|rcsb pdb:4Z1Q|rcsb pdb:4QB3|rcsb pdb:4Z1S|rcsb pdb:4Z93|rcsb pdb:4ZC9|rcsb pdb:4ZW1|rcsb pdb:5ACY|rcsb pdb:5AD2|rcsb pdb:5AD3|rcsb pdb:5BT4|rcsb pdb:5CFW|rcsb pdb:5COI|rcsb pdb:5CP5|rcsb pdb:5CPE|rcsb pdb:5CQT|rcsb pdb:5A5S|rcsb pdb:5CRM|rcsb pdb:5CRZ|rcsb pdb:5CS8|rcsb pdb:5CTL|rcsb pdb:5CY9|rcsb pdb:5D0C|rcsb pdb:5D24|rcsb pdb:5D25|rcsb pdb:5D26|rcsb pdb:5D3H|rcsb pdb:5D3J|rcsb pdb:5D3L|rcsb pdb:5D3N|rcsb pdb:5D3P|rcsb pdb:5A85|rcsb pdb:5D3R|rcsb pdb:5D3S|rcsb pdb:5D3T|rcsb pdb:5DLX|rcsb pdb:5DLZ|rcsb pdb:5DX4|rcsb pdb:5E0R|rcsb pdb:5EGU|rcsb pdb:5EI4|rcsb pdb:5EIS|rcsb pdb:5F5Z|rcsb pdb:5F60|rcsb pdb:5F61|rcsb pdb:5F62|rcsb pdb:5F63|rcsb pdb:5FBX|rcsb pdb:5H21|rcsb pdb:5HCL|rcsb pdb:5HLS|rcsb pdb:5HM0|rcsb pdb:5HQ5|rcsb pdb:5HQ6|rcsb pdb:5HQ7|rcsb pdb:5I80|rcsb pdb:5I88|rcsb pdb:5IGK|rcsb pdb:5JWM|rcsb pdb:5KDH|rcsb pdb:5KHM|rcsb pdb:5KJ0|rcsb pdb:5KU3|rcsb pdb:5LJ1|rcsb pdb:5LJ2|rcsb pdb:5LRQ|rcsb pdb:5LUU|rcsb pdb:5M39|rcsb pdb:5M3A|rcsb pdb:5MKZ|rcsb pdb:5DW2|rcsb pdb:5MLI|rcsb pdb:5N2M|rcsb pdb:5NNC|rcsb pdb:5NND|rcsb pdb:5NNE|rcsb pdb:5NNF|rcsb pdb:5NNG|rcsb pdb:5O97|rcsb pdb:5UES|rcsb pdb:5UET|rcsb pdb:5OVB|rcsb pdb:5OWM|rcsb pdb:5UEU|rcsb pdb:5UEV|rcsb pdb:5UEX|rcsb pdb:5UEY|rcsb pdb:5UEZ|rcsb pdb:5OWW|rcsb pdb:5UF0|rcsb pdb:5ULA|rcsb pdb:5UOO|rcsb pdb:5UVS|rcsb pdb:5UVT|rcsb pdb:5UVU|rcsb pdb:5UVV|rcsb pdb:5UVW|rcsb pdb:5T35|rcsb pdb:5TI2|rcsb pdb:5TI3|rcsb pdb:5TI4|rcsb pdb:5TI5|rcsb pdb:5TI6|rcsb pdb:5TI7|rcsb pdb:5U28|rcsb pdb:5U2C|rcsb pdb:5U2E|rcsb pdb:5U2F|rcsb pdb:5UVX|rcsb pdb:5UVY|rcsb pdb:5UVZ|rcsb pdb:5V67|rcsb pdb:5VBO|rcsb pdb:5VBP|rcsb pdb:5UEO|rcsb pdb:5VOM|rcsb pdb:5VZS|rcsb pdb:5W55|rcsb pdb:5WA5|rcsb pdb:5WMA|rcsb pdb:5WMD|rcsb pdb:5WMG|rcsb pdb:5WUU|rcsb pdb:5UEP|rcsb pdb:5XHY|rcsb pdb:5UEQ|rcsb pdb:5XI2|rcsb pdb:5XI3|rcsb pdb:5UER|rcsb pdb:5XI4|rcsb pdb:5Y1Y|rcsb pdb:5Y8C|rcsb pdb:5Y8W|rcsb pdb:5Y8Y|rcsb pdb:5Y8Z|rcsb pdb:6VIW|rcsb pdb:6VIX|rcsb pdb:6VIZ|ensembl:ENSP00000263377|ensembl:ENST00000360016|ensembl:ENSP00000353112|ensembl:ENST00000371835|ensembl:ENSP00000360901|ensembl:ENSP00000506350|rcsb pdb:7A9U|rcsb pdb:7AJN|rcsb pdb:7C2Z|rcsb pdb:7C6P|rcsb pdb:7JKX|rcsb pdb:7KHH|rcsb pdb:7KHL|rcsb pdb:7MCF|reactome:R-HSA-9679191|rcsb pdb:6ZF9|rcsb pdb:6VUC|rcsb pdb:6VUF|rcsb pdb:6VUJ|rcsb pdb:6WGX|rcsb pdb:6WW8|rcsb pdb:6X7B|rcsb pdb:6X7C|rcsb pdb:6X7D|rcsb pdb:6XUZ|rcsb pdb:6XV3|rcsb pdb:6XV7|rcsb pdb:6XVC|rcsb pdb:6YIN|rcsb pdb:6YQN|rcsb pdb:6YQO|rcsb pdb:6YQP|rcsb pdb:6YQZ|rcsb pdb:6Z7G|rcsb pdb:6Z7L|rcsb pdb:6Z7M|rcsb pdb:6ZB3|rcsb pdb:6ZCI|rcsb pdb:6ZED|rcsb pdb:6ZEL|rcsb pdb:6VUB|refseq:NP_001317313.1|refseq:XP_011526156.1|refseq:XP_011526158.1|dip:DIP-39776N ensembl:ENSG00000049541(gene)|ensembl:ENST00000055077(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0019899"(enzyme binding)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|mint:P35250|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-176187|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804756|reactome:R-HSA-69091|reactome:R-HSA-69473|refseq:NP_002905.2|refseq:NP_852136.1|refseq:NP_001265720.1|refseq:NP_001265721.1|refseq:NP_001265722.1|dip:DIP-34367N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:tzQWCG/IwJWaOJ7XO+pXHkPVg+w9606 rogid:36ppRbKXusdkqhmmoOTQ04BWv6I9606 rigid:K2edVBg9TqAqUXEY6y1Hf+1vwIs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60885 uniprotkb:P35249 intact:EBI-723869|uniprotkb:O60433|uniprotkb:Q86YS8|uniprotkb:Q96PD3|intact:EBI-28968271|ensembl:ENSP00000263377|ensembl:ENSP00000506350|uniprotkb:Q4G0X8 intact:EBI-476655|uniprotkb:Q6FHX7|ensembl:ENSP00000296273|ensembl:ENSP00000376272|uniprotkb:D3DNV2|uniprotkb:B4DM41 psi-mi:brd4_human(display_long)|uniprotkb:Protein HUNK1(gene name synonym)|uniprotkb:BRD4(gene name)|psi-mi:BRD4(display_short)|uniprotkb:HUNK1(gene name synonym) psi-mi:rfc4_human(display_long)|uniprotkb:Activator 1 subunit 4(gene name synonym)|uniprotkb:Replication factor C 37 kDa subunit(gene name synonym)|uniprotkb:Activator 1 37 kDa subunit(gene name synonym)|uniprotkb:RFC4(gene name)|psi-mi:RFC4(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476724|imex:IM-26985-307 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055114.1|refseq:NP_490597.1|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|ensembl:ENSG00000141867(gene)|ensembl:ENST00000263377(transcript)|ensembl:ENST00000679869(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0019899"(enzyme binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:1901407"(regulation of phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:2000002"(negative regulation of DNA damage checkpoint)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR001487(Bromodomain)|interpro:IPR018359|interpro:IPR027353|interpro:IPR031354|interpro:IPR036427|interpro:IPR038336|interpro:IPR043508|interpro:IPR043509|mint:O60885|rcsb pdb:2I8N|rcsb pdb:2LSP|rcsb pdb:2MJV|rcsb pdb:2N3K|rcsb pdb:2NCZ|rcsb pdb:2ND0|rcsb pdb:2ND1|rcsb pdb:2NNU|rcsb pdb:2OSS|rcsb pdb:2OUO|rcsb pdb:2YEL|rcsb pdb:2YEM|rcsb pdb:3MXF|rcsb pdb:5Y93|rcsb pdb:5Y94|rcsb pdb:5YOU|rcsb pdb:5YOV|rcsb pdb:5YQX|rcsb pdb:5Z1R|rcsb pdb:5Z1S|rcsb pdb:5Z1T|rcsb pdb:5Z5T|rcsb pdb:5Z5U|rcsb pdb:5Z5V|rcsb pdb:5Z8G|rcsb pdb:5Z8R|rcsb pdb:5Z8Z|rcsb pdb:5Z90|rcsb pdb:5Z9C|rcsb pdb:5Z9K|rcsb pdb:6AFR|rcsb pdb:6AJV|rcsb pdb:6AJW|rcsb pdb:6AJX|rcsb pdb:6AJY|rcsb pdb:6AJZ|rcsb pdb:6BN7|rcsb pdb:6BN8|rcsb pdb:6BN9|rcsb pdb:6BNB|rcsb pdb:6BNH|rcsb pdb:6BOY|rcsb pdb:6C7Q|rcsb pdb:6C7R|rcsb pdb:6CD4|rcsb pdb:6CD5|rcsb pdb:6CIS|rcsb pdb:6CIY|rcsb pdb:6CJ1|rcsb pdb:6CJ2|rcsb pdb:6CKR|rcsb pdb:6CKS|rcsb pdb:6CZU|rcsb pdb:6CZV|rcsb pdb:6DJC|rcsb pdb:6DL2|rcsb pdb:6DMJ|rcsb pdb:6DML|rcsb pdb:6DNE|rcsb pdb:6DUV|rcsb pdb:6FFD|rcsb pdb:6FNX|rcsb pdb:6FO5|rcsb pdb:6E4A|rcsb pdb:6FSY|rcsb pdb:6FT3|rcsb pdb:6FT4|rcsb pdb:6G0D|rcsb pdb:6G0E|rcsb pdb:6G0F|rcsb pdb:6G0G|rcsb pdb:6G0H|rcsb pdb:6G0O|rcsb pdb:6G0P|rcsb pdb:6G0Q|rcsb pdb:6G0R|rcsb pdb:6G0S|rcsb pdb:6HDQ|rcsb pdb:6HOV|rcsb pdb:6I7X|rcsb pdb:6I7Y|rcsb pdb:6IN1|rcsb pdb:6JI3|rcsb pdb:6JI4|rcsb pdb:6JI5|rcsb pdb:6JJ3|rcsb pdb:6JJ5|rcsb pdb:6JJ6|rcsb pdb:6JJB|rcsb pdb:6KEC|rcsb pdb:6KED|rcsb pdb:6KEE|rcsb pdb:6KEF|rcsb pdb:6KEG|rcsb pdb:6KEH|rcsb pdb:6KEI|rcsb pdb:6KEJ|rcsb pdb:6KEK|rcsb pdb:6KO2|rcsb pdb:6SB8|rcsb pdb:6SE4|rcsb pdb:6SIS|rcsb pdb:6LG4|rcsb pdb:6SWN|rcsb pdb:6SWQ|rcsb pdb:6TPX|rcsb pdb:6TPY|rcsb pdb:6TPZ|rcsb pdb:6U0D|rcsb pdb:6U6K|rcsb pdb:6U6L|rcsb pdb:6U72|rcsb pdb:6U74|rcsb pdb:6U8G|rcsb pdb:6U8I|rcsb pdb:6U8M|rcsb pdb:6ULS|rcsb pdb:6ULV|rcsb pdb:6UVJ|rcsb pdb:6UVM|rcsb pdb:6UWU|rcsb pdb:6UWX|rcsb pdb:6V0U|rcsb pdb:6V1K|rcsb pdb:6V1L|rcsb pdb:6V1U|rcsb pdb:3SVF|rcsb pdb:3SVG|rcsb pdb:3U5J|rcsb pdb:3U5K|rcsb pdb:3U5L|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3ZYU|rcsb pdb:4A9L|rcsb pdb:4BJX|rcsb pdb:4BW1|rcsb pdb:4BW2|rcsb pdb:4BW3|rcsb pdb:4BW4|rcsb pdb:4C66|rcsb pdb:4C67|rcsb pdb:3P5O|rcsb pdb:4CFK|rcsb pdb:4CFL|rcsb pdb:4CL9|rcsb pdb:6LG6|rcsb pdb:6LG7|rcsb pdb:6LG8|rcsb pdb:6LG9|rcsb pdb:6LIH|rcsb pdb:6LIM|rcsb pdb:6MAU|rcsb pdb:6MH1|rcsb pdb:6MH7|rcsb pdb:6MNL|rcsb pdb:6P05|rcsb pdb:6PRT|rcsb pdb:6PS9|rcsb pdb:6PSB|rcsb pdb:6Q3Y|rcsb pdb:6LG5|rcsb pdb:6Q3Z|rcsb pdb:6RWJ|rcsb pdb:6S25|rcsb pdb:6S4B|rcsb pdb:6S6K|rcsb pdb:6SA2|rcsb pdb:6SA3|rcsb pdb:6SAH|rcsb pdb:6SAJ|rcsb pdb:4DON|rcsb pdb:4E96|rcsb pdb:4F3I|rcsb pdb:4GPJ|rcsb pdb:4HBV|rcsb pdb:4HBW|rcsb pdb:4HBX|rcsb pdb:4HBY|rcsb pdb:4HXK|rcsb pdb:4HXL|rcsb pdb:4HXM|rcsb pdb:4HXN|rcsb pdb:4HXO|rcsb pdb:4HXP|rcsb pdb:4HXR|rcsb pdb:4HXS|rcsb pdb:4IOO|rcsb pdb:4IOQ|rcsb pdb:4IOR|rcsb pdb:4J0R|rcsb pdb:4J0S|rcsb pdb:4J3I|rcsb pdb:4CLB|rcsb pdb:4KV1|rcsb pdb:4KV4|rcsb pdb:4LR6|rcsb pdb:4LRG|rcsb pdb:4LYI|rcsb pdb:4LYS|rcsb pdb:4LYW|rcsb pdb:4LZR|rcsb pdb:4LZS|rcsb pdb:4MEN|rcsb pdb:4MEO|rcsb pdb:4MEP|rcsb pdb:4MEQ|rcsb pdb:4MR3|rcsb pdb:4MR4|rcsb pdb:4NQM|rcsb pdb:4NR8|rcsb pdb:4NUC|rcsb pdb:4NUD|rcsb pdb:4NUE|rcsb pdb:4O70|rcsb pdb:4O71|rcsb pdb:4O72|rcsb pdb:4O74|rcsb pdb:4O75|rcsb pdb:4O76|rcsb pdb:4O77|rcsb pdb:4O78|rcsb pdb:4O7A|rcsb pdb:4O7B|rcsb pdb:4O7C|rcsb pdb:4O7E|rcsb pdb:4O7F|rcsb pdb:4OGI|rcsb pdb:4OGJ|rcsb pdb:4PCE|rcsb pdb:4PCI|rcsb pdb:4PS5|rcsb pdb:4QR3|rcsb pdb:4QR4|rcsb pdb:4QR5|rcsb pdb:4QZS|rcsb pdb:4UIX|rcsb pdb:4UIY|rcsb pdb:4UIZ|rcsb pdb:4UYD|rcsb pdb:4WHW|rcsb pdb:4WIV|rcsb pdb:4X2I|rcsb pdb:4XY9|rcsb pdb:4XYA|rcsb pdb:4YH3|rcsb pdb:4YH4|rcsb pdb:4Z1Q|rcsb pdb:4QB3|rcsb pdb:4Z1S|rcsb pdb:4Z93|rcsb pdb:4ZC9|rcsb pdb:4ZW1|rcsb pdb:5ACY|rcsb pdb:5AD2|rcsb pdb:5AD3|rcsb pdb:5BT4|rcsb pdb:5CFW|rcsb pdb:5COI|rcsb pdb:5CP5|rcsb pdb:5CPE|rcsb pdb:5CQT|rcsb pdb:5A5S|rcsb pdb:5CRM|rcsb pdb:5CRZ|rcsb pdb:5CS8|rcsb pdb:5CTL|rcsb pdb:5CY9|rcsb pdb:5D0C|rcsb pdb:5D24|rcsb pdb:5D25|rcsb pdb:5D26|rcsb pdb:5D3H|rcsb pdb:5D3J|rcsb pdb:5D3L|rcsb pdb:5D3N|rcsb pdb:5D3P|rcsb pdb:5A85|rcsb pdb:5D3R|rcsb pdb:5D3S|rcsb pdb:5D3T|rcsb pdb:5DLX|rcsb pdb:5DLZ|rcsb pdb:5DX4|rcsb pdb:5E0R|rcsb pdb:5EGU|rcsb pdb:5EI4|rcsb pdb:5EIS|rcsb pdb:5F5Z|rcsb pdb:5F60|rcsb pdb:5F61|rcsb pdb:5F62|rcsb pdb:5F63|rcsb pdb:5FBX|rcsb pdb:5H21|rcsb pdb:5HCL|rcsb pdb:5HLS|rcsb pdb:5HM0|rcsb pdb:5HQ5|rcsb pdb:5HQ6|rcsb pdb:5HQ7|rcsb pdb:5I80|rcsb pdb:5I88|rcsb pdb:5IGK|rcsb pdb:5JWM|rcsb pdb:5KDH|rcsb pdb:5KHM|rcsb pdb:5KJ0|rcsb pdb:5KU3|rcsb pdb:5LJ1|rcsb pdb:5LJ2|rcsb pdb:5LRQ|rcsb pdb:5LUU|rcsb pdb:5M39|rcsb pdb:5M3A|rcsb pdb:5MKZ|rcsb pdb:5DW2|rcsb pdb:5MLI|rcsb pdb:5N2M|rcsb pdb:5NNC|rcsb pdb:5NND|rcsb pdb:5NNE|rcsb pdb:5NNF|rcsb pdb:5NNG|rcsb pdb:5O97|rcsb pdb:5UES|rcsb pdb:5UET|rcsb pdb:5OVB|rcsb pdb:5OWM|rcsb pdb:5UEU|rcsb pdb:5UEV|rcsb pdb:5UEX|rcsb pdb:5UEY|rcsb pdb:5UEZ|rcsb pdb:5OWW|rcsb pdb:5UF0|rcsb pdb:5ULA|rcsb pdb:5UOO|rcsb pdb:5UVS|rcsb pdb:5UVT|rcsb pdb:5UVU|rcsb pdb:5UVV|rcsb pdb:5UVW|rcsb pdb:5T35|rcsb pdb:5TI2|rcsb pdb:5TI3|rcsb pdb:5TI4|rcsb pdb:5TI5|rcsb pdb:5TI6|rcsb pdb:5TI7|rcsb pdb:5U28|rcsb pdb:5U2C|rcsb pdb:5U2E|rcsb pdb:5U2F|rcsb pdb:5UVX|rcsb pdb:5UVY|rcsb pdb:5UVZ|rcsb pdb:5V67|rcsb pdb:5VBO|rcsb pdb:5VBP|rcsb pdb:5UEO|rcsb pdb:5VOM|rcsb pdb:5VZS|rcsb pdb:5W55|rcsb pdb:5WA5|rcsb pdb:5WMA|rcsb pdb:5WMD|rcsb pdb:5WMG|rcsb pdb:5WUU|rcsb pdb:5UEP|rcsb pdb:5XHY|rcsb pdb:5UEQ|rcsb pdb:5XI2|rcsb pdb:5XI3|rcsb pdb:5UER|rcsb pdb:5XI4|rcsb pdb:5Y1Y|rcsb pdb:5Y8C|rcsb pdb:5Y8W|rcsb pdb:5Y8Y|rcsb pdb:5Y8Z|rcsb pdb:6VIW|rcsb pdb:6VIX|rcsb pdb:6VIZ|ensembl:ENSP00000263377|ensembl:ENST00000360016|ensembl:ENSP00000353112|ensembl:ENST00000371835|ensembl:ENSP00000360901|ensembl:ENSP00000506350|rcsb pdb:7A9U|rcsb pdb:7AJN|rcsb pdb:7C2Z|rcsb pdb:7C6P|rcsb pdb:7JKX|rcsb pdb:7KHH|rcsb pdb:7KHL|rcsb pdb:7MCF|reactome:R-HSA-9679191|rcsb pdb:6ZF9|rcsb pdb:6VUC|rcsb pdb:6VUF|rcsb pdb:6VUJ|rcsb pdb:6WGX|rcsb pdb:6WW8|rcsb pdb:6X7B|rcsb pdb:6X7C|rcsb pdb:6X7D|rcsb pdb:6XUZ|rcsb pdb:6XV3|rcsb pdb:6XV7|rcsb pdb:6XVC|rcsb pdb:6YIN|rcsb pdb:6YQN|rcsb pdb:6YQO|rcsb pdb:6YQP|rcsb pdb:6YQZ|rcsb pdb:6Z7G|rcsb pdb:6Z7L|rcsb pdb:6Z7M|rcsb pdb:6ZB3|rcsb pdb:6ZCI|rcsb pdb:6ZED|rcsb pdb:6ZEL|rcsb pdb:6VUB|refseq:NP_001317313.1|refseq:XP_011526156.1|refseq:XP_011526158.1|dip:DIP-39776N refseq:NP_002907.1|refseq:NP_853551.1|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|ensembl:ENSG00000163918(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0031391"(Elg1 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|ensembl:ENST00000296273(transcript)|ensembl:ENST00000392481(transcript)|mint:P35249|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804756|reactome:R-HSA-69091|reactome:R-HSA-69473|reactome:R-HSA-176187|dip:DIP-24267N - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:tzQWCG/IwJWaOJ7XO+pXHkPVg+w9606 rogid:zn+V998ZRpYIdHmG87ExC6LFc0w9606 rigid:K2edVBg9TqAqUXEY6y1Hf+1vwIs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60885 uniprotkb:P40937 intact:EBI-723869|uniprotkb:O60433|uniprotkb:Q86YS8|uniprotkb:Q96PD3|intact:EBI-28968271|ensembl:ENSP00000263377|ensembl:ENSP00000506350|uniprotkb:Q4G0X8 intact:EBI-712376|ensembl:ENSP00000408295|uniprotkb:A8MZ62|uniprotkb:B3KSX8 psi-mi:brd4_human(display_long)|uniprotkb:Protein HUNK1(gene name synonym)|uniprotkb:BRD4(gene name)|psi-mi:BRD4(display_short)|uniprotkb:HUNK1(gene name synonym) psi-mi:rfc5_human(display_long)|uniprotkb:Activator 1 subunit 5(gene name synonym)|uniprotkb:Replication factor C 36 kDa subunit(gene name synonym)|uniprotkb:Activator 1 36 kDa subunit(gene name synonym)|uniprotkb:RFC5(gene name)|psi-mi:RFC5(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476724|imex:IM-26985-307 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055114.1|refseq:NP_490597.1|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|ensembl:ENSG00000141867(gene)|ensembl:ENST00000263377(transcript)|ensembl:ENST00000679869(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0019899"(enzyme binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:1901407"(regulation of phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:2000002"(negative regulation of DNA damage checkpoint)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR001487(Bromodomain)|interpro:IPR018359|interpro:IPR027353|interpro:IPR031354|interpro:IPR036427|interpro:IPR038336|interpro:IPR043508|interpro:IPR043509|mint:O60885|rcsb pdb:2I8N|rcsb pdb:2LSP|rcsb pdb:2MJV|rcsb pdb:2N3K|rcsb pdb:2NCZ|rcsb pdb:2ND0|rcsb pdb:2ND1|rcsb pdb:2NNU|rcsb pdb:2OSS|rcsb pdb:2OUO|rcsb pdb:2YEL|rcsb pdb:2YEM|rcsb pdb:3MXF|rcsb pdb:5Y93|rcsb pdb:5Y94|rcsb pdb:5YOU|rcsb pdb:5YOV|rcsb pdb:5YQX|rcsb pdb:5Z1R|rcsb pdb:5Z1S|rcsb pdb:5Z1T|rcsb pdb:5Z5T|rcsb pdb:5Z5U|rcsb pdb:5Z5V|rcsb pdb:5Z8G|rcsb pdb:5Z8R|rcsb pdb:5Z8Z|rcsb pdb:5Z90|rcsb pdb:5Z9C|rcsb pdb:5Z9K|rcsb pdb:6AFR|rcsb pdb:6AJV|rcsb pdb:6AJW|rcsb pdb:6AJX|rcsb pdb:6AJY|rcsb pdb:6AJZ|rcsb pdb:6BN7|rcsb pdb:6BN8|rcsb pdb:6BN9|rcsb pdb:6BNB|rcsb pdb:6BNH|rcsb pdb:6BOY|rcsb pdb:6C7Q|rcsb pdb:6C7R|rcsb pdb:6CD4|rcsb pdb:6CD5|rcsb pdb:6CIS|rcsb pdb:6CIY|rcsb pdb:6CJ1|rcsb pdb:6CJ2|rcsb pdb:6CKR|rcsb pdb:6CKS|rcsb pdb:6CZU|rcsb pdb:6CZV|rcsb pdb:6DJC|rcsb pdb:6DL2|rcsb pdb:6DMJ|rcsb pdb:6DML|rcsb pdb:6DNE|rcsb pdb:6DUV|rcsb pdb:6FFD|rcsb pdb:6FNX|rcsb pdb:6FO5|rcsb pdb:6E4A|rcsb pdb:6FSY|rcsb pdb:6FT3|rcsb pdb:6FT4|rcsb pdb:6G0D|rcsb pdb:6G0E|rcsb pdb:6G0F|rcsb pdb:6G0G|rcsb pdb:6G0H|rcsb pdb:6G0O|rcsb pdb:6G0P|rcsb pdb:6G0Q|rcsb pdb:6G0R|rcsb pdb:6G0S|rcsb pdb:6HDQ|rcsb pdb:6HOV|rcsb pdb:6I7X|rcsb pdb:6I7Y|rcsb pdb:6IN1|rcsb pdb:6JI3|rcsb pdb:6JI4|rcsb pdb:6JI5|rcsb pdb:6JJ3|rcsb pdb:6JJ5|rcsb pdb:6JJ6|rcsb pdb:6JJB|rcsb pdb:6KEC|rcsb pdb:6KED|rcsb pdb:6KEE|rcsb pdb:6KEF|rcsb pdb:6KEG|rcsb pdb:6KEH|rcsb pdb:6KEI|rcsb pdb:6KEJ|rcsb pdb:6KEK|rcsb pdb:6KO2|rcsb pdb:6SB8|rcsb pdb:6SE4|rcsb pdb:6SIS|rcsb pdb:6LG4|rcsb pdb:6SWN|rcsb pdb:6SWQ|rcsb pdb:6TPX|rcsb pdb:6TPY|rcsb pdb:6TPZ|rcsb pdb:6U0D|rcsb pdb:6U6K|rcsb pdb:6U6L|rcsb pdb:6U72|rcsb pdb:6U74|rcsb pdb:6U8G|rcsb pdb:6U8I|rcsb pdb:6U8M|rcsb pdb:6ULS|rcsb pdb:6ULV|rcsb pdb:6UVJ|rcsb pdb:6UVM|rcsb pdb:6UWU|rcsb pdb:6UWX|rcsb pdb:6V0U|rcsb pdb:6V1K|rcsb pdb:6V1L|rcsb pdb:6V1U|rcsb pdb:3SVF|rcsb pdb:3SVG|rcsb pdb:3U5J|rcsb pdb:3U5K|rcsb pdb:3U5L|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3ZYU|rcsb pdb:4A9L|rcsb pdb:4BJX|rcsb pdb:4BW1|rcsb pdb:4BW2|rcsb pdb:4BW3|rcsb pdb:4BW4|rcsb pdb:4C66|rcsb pdb:4C67|rcsb pdb:3P5O|rcsb pdb:4CFK|rcsb pdb:4CFL|rcsb pdb:4CL9|rcsb pdb:6LG6|rcsb pdb:6LG7|rcsb pdb:6LG8|rcsb pdb:6LG9|rcsb pdb:6LIH|rcsb pdb:6LIM|rcsb pdb:6MAU|rcsb pdb:6MH1|rcsb pdb:6MH7|rcsb pdb:6MNL|rcsb pdb:6P05|rcsb pdb:6PRT|rcsb pdb:6PS9|rcsb pdb:6PSB|rcsb pdb:6Q3Y|rcsb pdb:6LG5|rcsb pdb:6Q3Z|rcsb pdb:6RWJ|rcsb pdb:6S25|rcsb pdb:6S4B|rcsb pdb:6S6K|rcsb pdb:6SA2|rcsb pdb:6SA3|rcsb pdb:6SAH|rcsb pdb:6SAJ|rcsb pdb:4DON|rcsb pdb:4E96|rcsb pdb:4F3I|rcsb pdb:4GPJ|rcsb pdb:4HBV|rcsb pdb:4HBW|rcsb pdb:4HBX|rcsb pdb:4HBY|rcsb pdb:4HXK|rcsb pdb:4HXL|rcsb pdb:4HXM|rcsb pdb:4HXN|rcsb pdb:4HXO|rcsb pdb:4HXP|rcsb pdb:4HXR|rcsb pdb:4HXS|rcsb pdb:4IOO|rcsb pdb:4IOQ|rcsb pdb:4IOR|rcsb pdb:4J0R|rcsb pdb:4J0S|rcsb pdb:4J3I|rcsb pdb:4CLB|rcsb pdb:4KV1|rcsb pdb:4KV4|rcsb pdb:4LR6|rcsb pdb:4LRG|rcsb pdb:4LYI|rcsb pdb:4LYS|rcsb pdb:4LYW|rcsb pdb:4LZR|rcsb pdb:4LZS|rcsb pdb:4MEN|rcsb pdb:4MEO|rcsb pdb:4MEP|rcsb pdb:4MEQ|rcsb pdb:4MR3|rcsb pdb:4MR4|rcsb pdb:4NQM|rcsb pdb:4NR8|rcsb pdb:4NUC|rcsb pdb:4NUD|rcsb pdb:4NUE|rcsb pdb:4O70|rcsb pdb:4O71|rcsb pdb:4O72|rcsb pdb:4O74|rcsb pdb:4O75|rcsb pdb:4O76|rcsb pdb:4O77|rcsb pdb:4O78|rcsb pdb:4O7A|rcsb pdb:4O7B|rcsb pdb:4O7C|rcsb pdb:4O7E|rcsb pdb:4O7F|rcsb pdb:4OGI|rcsb pdb:4OGJ|rcsb pdb:4PCE|rcsb pdb:4PCI|rcsb pdb:4PS5|rcsb pdb:4QR3|rcsb pdb:4QR4|rcsb pdb:4QR5|rcsb pdb:4QZS|rcsb pdb:4UIX|rcsb pdb:4UIY|rcsb pdb:4UIZ|rcsb pdb:4UYD|rcsb pdb:4WHW|rcsb pdb:4WIV|rcsb pdb:4X2I|rcsb pdb:4XY9|rcsb pdb:4XYA|rcsb pdb:4YH3|rcsb pdb:4YH4|rcsb pdb:4Z1Q|rcsb pdb:4QB3|rcsb pdb:4Z1S|rcsb pdb:4Z93|rcsb pdb:4ZC9|rcsb pdb:4ZW1|rcsb pdb:5ACY|rcsb pdb:5AD2|rcsb pdb:5AD3|rcsb pdb:5BT4|rcsb pdb:5CFW|rcsb pdb:5COI|rcsb pdb:5CP5|rcsb pdb:5CPE|rcsb pdb:5CQT|rcsb pdb:5A5S|rcsb pdb:5CRM|rcsb pdb:5CRZ|rcsb pdb:5CS8|rcsb pdb:5CTL|rcsb pdb:5CY9|rcsb pdb:5D0C|rcsb pdb:5D24|rcsb pdb:5D25|rcsb pdb:5D26|rcsb pdb:5D3H|rcsb pdb:5D3J|rcsb pdb:5D3L|rcsb pdb:5D3N|rcsb pdb:5D3P|rcsb pdb:5A85|rcsb pdb:5D3R|rcsb pdb:5D3S|rcsb pdb:5D3T|rcsb pdb:5DLX|rcsb pdb:5DLZ|rcsb pdb:5DX4|rcsb pdb:5E0R|rcsb pdb:5EGU|rcsb pdb:5EI4|rcsb pdb:5EIS|rcsb pdb:5F5Z|rcsb pdb:5F60|rcsb pdb:5F61|rcsb pdb:5F62|rcsb pdb:5F63|rcsb pdb:5FBX|rcsb pdb:5H21|rcsb pdb:5HCL|rcsb pdb:5HLS|rcsb pdb:5HM0|rcsb pdb:5HQ5|rcsb pdb:5HQ6|rcsb pdb:5HQ7|rcsb pdb:5I80|rcsb pdb:5I88|rcsb pdb:5IGK|rcsb pdb:5JWM|rcsb pdb:5KDH|rcsb pdb:5KHM|rcsb pdb:5KJ0|rcsb pdb:5KU3|rcsb pdb:5LJ1|rcsb pdb:5LJ2|rcsb pdb:5LRQ|rcsb pdb:5LUU|rcsb pdb:5M39|rcsb pdb:5M3A|rcsb pdb:5MKZ|rcsb pdb:5DW2|rcsb pdb:5MLI|rcsb pdb:5N2M|rcsb pdb:5NNC|rcsb pdb:5NND|rcsb pdb:5NNE|rcsb pdb:5NNF|rcsb pdb:5NNG|rcsb pdb:5O97|rcsb pdb:5UES|rcsb pdb:5UET|rcsb pdb:5OVB|rcsb pdb:5OWM|rcsb pdb:5UEU|rcsb pdb:5UEV|rcsb pdb:5UEX|rcsb pdb:5UEY|rcsb pdb:5UEZ|rcsb pdb:5OWW|rcsb pdb:5UF0|rcsb pdb:5ULA|rcsb pdb:5UOO|rcsb pdb:5UVS|rcsb pdb:5UVT|rcsb pdb:5UVU|rcsb pdb:5UVV|rcsb pdb:5UVW|rcsb pdb:5T35|rcsb pdb:5TI2|rcsb pdb:5TI3|rcsb pdb:5TI4|rcsb pdb:5TI5|rcsb pdb:5TI6|rcsb pdb:5TI7|rcsb pdb:5U28|rcsb pdb:5U2C|rcsb pdb:5U2E|rcsb pdb:5U2F|rcsb pdb:5UVX|rcsb pdb:5UVY|rcsb pdb:5UVZ|rcsb pdb:5V67|rcsb pdb:5VBO|rcsb pdb:5VBP|rcsb pdb:5UEO|rcsb pdb:5VOM|rcsb pdb:5VZS|rcsb pdb:5W55|rcsb pdb:5WA5|rcsb pdb:5WMA|rcsb pdb:5WMD|rcsb pdb:5WMG|rcsb pdb:5WUU|rcsb pdb:5UEP|rcsb pdb:5XHY|rcsb pdb:5UEQ|rcsb pdb:5XI2|rcsb pdb:5XI3|rcsb pdb:5UER|rcsb pdb:5XI4|rcsb pdb:5Y1Y|rcsb pdb:5Y8C|rcsb pdb:5Y8W|rcsb pdb:5Y8Y|rcsb pdb:5Y8Z|rcsb pdb:6VIW|rcsb pdb:6VIX|rcsb pdb:6VIZ|ensembl:ENSP00000263377|ensembl:ENST00000360016|ensembl:ENSP00000353112|ensembl:ENST00000371835|ensembl:ENSP00000360901|ensembl:ENSP00000506350|rcsb pdb:7A9U|rcsb pdb:7AJN|rcsb pdb:7C2Z|rcsb pdb:7C6P|rcsb pdb:7JKX|rcsb pdb:7KHH|rcsb pdb:7KHL|rcsb pdb:7MCF|reactome:R-HSA-9679191|rcsb pdb:6ZF9|rcsb pdb:6VUC|rcsb pdb:6VUF|rcsb pdb:6VUJ|rcsb pdb:6WGX|rcsb pdb:6WW8|rcsb pdb:6X7B|rcsb pdb:6X7C|rcsb pdb:6X7D|rcsb pdb:6XUZ|rcsb pdb:6XV3|rcsb pdb:6XV7|rcsb pdb:6XVC|rcsb pdb:6YIN|rcsb pdb:6YQN|rcsb pdb:6YQO|rcsb pdb:6YQP|rcsb pdb:6YQZ|rcsb pdb:6Z7G|rcsb pdb:6Z7L|rcsb pdb:6Z7M|rcsb pdb:6ZB3|rcsb pdb:6ZCI|rcsb pdb:6ZED|rcsb pdb:6ZEL|rcsb pdb:6VUB|refseq:NP_001317313.1|refseq:XP_011526156.1|refseq:XP_011526158.1|dip:DIP-39776N refseq:NP_031396.1|refseq:NP_853556.2|ensembl:ENSG00000111445(gene)|ensembl:ENST00000454402(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0019899"(enzyme binding)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|mint:P40937|rcsb pdb:1LFS|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-176187|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804756|reactome:R-HSA-69091|reactome:R-HSA-69473|refseq:XP_011536945.1|refseq:XP_011536947.1|refseq:NP_001123584.1|refseq:NP_001123585.1|dip:DIP-36433N - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:tzQWCG/IwJWaOJ7XO+pXHkPVg+w9606 rogid:F7oadHDk6fkhHn+3rDF9K2JHSl49606 rigid:K2edVBg9TqAqUXEY6y1Hf+1vwIs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60885 uniprotkb:P01037 intact:EBI-723869|uniprotkb:O60433|uniprotkb:Q86YS8|uniprotkb:Q96PD3|intact:EBI-28968271|ensembl:ENSP00000263377|ensembl:ENSP00000506350|uniprotkb:Q4G0X8 intact:EBI-1056240|uniprotkb:Q96LE6|uniprotkb:Q9UCQ6|ensembl:ENSP00000305731|ensembl:ENSP00000381439 psi-mi:brd4_human(display_long)|uniprotkb:Protein HUNK1(gene name synonym)|uniprotkb:BRD4(gene name)|psi-mi:BRD4(display_short)|uniprotkb:HUNK1(gene name synonym) psi-mi:cytn_human(display_long)|uniprotkb:CST1(gene name)|psi-mi:CST1(display_short)|uniprotkb:Cystatin-1(gene name synonym)|uniprotkb:Salivary cystatin-SA-1(gene name synonym)|uniprotkb:Cystain-SA-I(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476724|imex:IM-26985-307 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055114.1|refseq:NP_490597.1|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|ensembl:ENSG00000141867(gene)|ensembl:ENST00000263377(transcript)|ensembl:ENST00000679869(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0019899"(enzyme binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:1901407"(regulation of phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:2000002"(negative regulation of DNA damage checkpoint)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR001487(Bromodomain)|interpro:IPR018359|interpro:IPR027353|interpro:IPR031354|interpro:IPR036427|interpro:IPR038336|interpro:IPR043508|interpro:IPR043509|mint:O60885|rcsb pdb:2I8N|rcsb pdb:2LSP|rcsb pdb:2MJV|rcsb pdb:2N3K|rcsb pdb:2NCZ|rcsb pdb:2ND0|rcsb pdb:2ND1|rcsb pdb:2NNU|rcsb pdb:2OSS|rcsb pdb:2OUO|rcsb pdb:2YEL|rcsb pdb:2YEM|rcsb pdb:3MXF|rcsb pdb:5Y93|rcsb pdb:5Y94|rcsb pdb:5YOU|rcsb pdb:5YOV|rcsb pdb:5YQX|rcsb pdb:5Z1R|rcsb pdb:5Z1S|rcsb pdb:5Z1T|rcsb pdb:5Z5T|rcsb pdb:5Z5U|rcsb pdb:5Z5V|rcsb pdb:5Z8G|rcsb pdb:5Z8R|rcsb pdb:5Z8Z|rcsb pdb:5Z90|rcsb pdb:5Z9C|rcsb pdb:5Z9K|rcsb pdb:6AFR|rcsb pdb:6AJV|rcsb pdb:6AJW|rcsb pdb:6AJX|rcsb pdb:6AJY|rcsb pdb:6AJZ|rcsb pdb:6BN7|rcsb pdb:6BN8|rcsb pdb:6BN9|rcsb pdb:6BNB|rcsb pdb:6BNH|rcsb pdb:6BOY|rcsb pdb:6C7Q|rcsb pdb:6C7R|rcsb pdb:6CD4|rcsb pdb:6CD5|rcsb pdb:6CIS|rcsb pdb:6CIY|rcsb pdb:6CJ1|rcsb pdb:6CJ2|rcsb pdb:6CKR|rcsb pdb:6CKS|rcsb pdb:6CZU|rcsb pdb:6CZV|rcsb pdb:6DJC|rcsb pdb:6DL2|rcsb pdb:6DMJ|rcsb pdb:6DML|rcsb pdb:6DNE|rcsb pdb:6DUV|rcsb pdb:6FFD|rcsb pdb:6FNX|rcsb pdb:6FO5|rcsb pdb:6E4A|rcsb pdb:6FSY|rcsb pdb:6FT3|rcsb pdb:6FT4|rcsb pdb:6G0D|rcsb pdb:6G0E|rcsb pdb:6G0F|rcsb pdb:6G0G|rcsb pdb:6G0H|rcsb pdb:6G0O|rcsb pdb:6G0P|rcsb pdb:6G0Q|rcsb pdb:6G0R|rcsb pdb:6G0S|rcsb pdb:6HDQ|rcsb pdb:6HOV|rcsb pdb:6I7X|rcsb pdb:6I7Y|rcsb pdb:6IN1|rcsb pdb:6JI3|rcsb pdb:6JI4|rcsb pdb:6JI5|rcsb pdb:6JJ3|rcsb pdb:6JJ5|rcsb pdb:6JJ6|rcsb pdb:6JJB|rcsb pdb:6KEC|rcsb pdb:6KED|rcsb pdb:6KEE|rcsb pdb:6KEF|rcsb pdb:6KEG|rcsb pdb:6KEH|rcsb pdb:6KEI|rcsb pdb:6KEJ|rcsb pdb:6KEK|rcsb pdb:6KO2|rcsb pdb:6SB8|rcsb pdb:6SE4|rcsb pdb:6SIS|rcsb pdb:6LG4|rcsb pdb:6SWN|rcsb pdb:6SWQ|rcsb pdb:6TPX|rcsb pdb:6TPY|rcsb pdb:6TPZ|rcsb pdb:6U0D|rcsb pdb:6U6K|rcsb pdb:6U6L|rcsb pdb:6U72|rcsb pdb:6U74|rcsb pdb:6U8G|rcsb pdb:6U8I|rcsb pdb:6U8M|rcsb pdb:6ULS|rcsb pdb:6ULV|rcsb pdb:6UVJ|rcsb pdb:6UVM|rcsb pdb:6UWU|rcsb pdb:6UWX|rcsb pdb:6V0U|rcsb pdb:6V1K|rcsb pdb:6V1L|rcsb pdb:6V1U|rcsb pdb:3SVF|rcsb pdb:3SVG|rcsb pdb:3U5J|rcsb pdb:3U5K|rcsb pdb:3U5L|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3ZYU|rcsb pdb:4A9L|rcsb pdb:4BJX|rcsb pdb:4BW1|rcsb pdb:4BW2|rcsb pdb:4BW3|rcsb pdb:4BW4|rcsb pdb:4C66|rcsb pdb:4C67|rcsb pdb:3P5O|rcsb pdb:4CFK|rcsb pdb:4CFL|rcsb pdb:4CL9|rcsb pdb:6LG6|rcsb pdb:6LG7|rcsb pdb:6LG8|rcsb pdb:6LG9|rcsb pdb:6LIH|rcsb pdb:6LIM|rcsb pdb:6MAU|rcsb pdb:6MH1|rcsb pdb:6MH7|rcsb pdb:6MNL|rcsb pdb:6P05|rcsb pdb:6PRT|rcsb pdb:6PS9|rcsb pdb:6PSB|rcsb pdb:6Q3Y|rcsb pdb:6LG5|rcsb pdb:6Q3Z|rcsb pdb:6RWJ|rcsb pdb:6S25|rcsb pdb:6S4B|rcsb pdb:6S6K|rcsb pdb:6SA2|rcsb pdb:6SA3|rcsb pdb:6SAH|rcsb pdb:6SAJ|rcsb pdb:4DON|rcsb pdb:4E96|rcsb pdb:4F3I|rcsb pdb:4GPJ|rcsb pdb:4HBV|rcsb pdb:4HBW|rcsb pdb:4HBX|rcsb pdb:4HBY|rcsb pdb:4HXK|rcsb pdb:4HXL|rcsb pdb:4HXM|rcsb pdb:4HXN|rcsb pdb:4HXO|rcsb pdb:4HXP|rcsb pdb:4HXR|rcsb pdb:4HXS|rcsb pdb:4IOO|rcsb pdb:4IOQ|rcsb pdb:4IOR|rcsb pdb:4J0R|rcsb pdb:4J0S|rcsb pdb:4J3I|rcsb pdb:4CLB|rcsb pdb:4KV1|rcsb pdb:4KV4|rcsb pdb:4LR6|rcsb pdb:4LRG|rcsb pdb:4LYI|rcsb pdb:4LYS|rcsb pdb:4LYW|rcsb pdb:4LZR|rcsb pdb:4LZS|rcsb pdb:4MEN|rcsb pdb:4MEO|rcsb pdb:4MEP|rcsb pdb:4MEQ|rcsb pdb:4MR3|rcsb pdb:4MR4|rcsb pdb:4NQM|rcsb pdb:4NR8|rcsb pdb:4NUC|rcsb pdb:4NUD|rcsb pdb:4NUE|rcsb pdb:4O70|rcsb pdb:4O71|rcsb pdb:4O72|rcsb pdb:4O74|rcsb pdb:4O75|rcsb pdb:4O76|rcsb pdb:4O77|rcsb pdb:4O78|rcsb pdb:4O7A|rcsb pdb:4O7B|rcsb pdb:4O7C|rcsb pdb:4O7E|rcsb pdb:4O7F|rcsb pdb:4OGI|rcsb pdb:4OGJ|rcsb pdb:4PCE|rcsb pdb:4PCI|rcsb pdb:4PS5|rcsb pdb:4QR3|rcsb pdb:4QR4|rcsb pdb:4QR5|rcsb pdb:4QZS|rcsb pdb:4UIX|rcsb pdb:4UIY|rcsb pdb:4UIZ|rcsb pdb:4UYD|rcsb pdb:4WHW|rcsb pdb:4WIV|rcsb pdb:4X2I|rcsb pdb:4XY9|rcsb pdb:4XYA|rcsb pdb:4YH3|rcsb pdb:4YH4|rcsb pdb:4Z1Q|rcsb pdb:4QB3|rcsb pdb:4Z1S|rcsb pdb:4Z93|rcsb pdb:4ZC9|rcsb pdb:4ZW1|rcsb pdb:5ACY|rcsb pdb:5AD2|rcsb pdb:5AD3|rcsb pdb:5BT4|rcsb pdb:5CFW|rcsb pdb:5COI|rcsb pdb:5CP5|rcsb pdb:5CPE|rcsb pdb:5CQT|rcsb pdb:5A5S|rcsb pdb:5CRM|rcsb pdb:5CRZ|rcsb pdb:5CS8|rcsb pdb:5CTL|rcsb pdb:5CY9|rcsb pdb:5D0C|rcsb pdb:5D24|rcsb pdb:5D25|rcsb pdb:5D26|rcsb pdb:5D3H|rcsb pdb:5D3J|rcsb pdb:5D3L|rcsb pdb:5D3N|rcsb pdb:5D3P|rcsb pdb:5A85|rcsb pdb:5D3R|rcsb pdb:5D3S|rcsb pdb:5D3T|rcsb pdb:5DLX|rcsb pdb:5DLZ|rcsb pdb:5DX4|rcsb pdb:5E0R|rcsb pdb:5EGU|rcsb pdb:5EI4|rcsb pdb:5EIS|rcsb pdb:5F5Z|rcsb pdb:5F60|rcsb pdb:5F61|rcsb pdb:5F62|rcsb pdb:5F63|rcsb pdb:5FBX|rcsb pdb:5H21|rcsb pdb:5HCL|rcsb pdb:5HLS|rcsb pdb:5HM0|rcsb pdb:5HQ5|rcsb pdb:5HQ6|rcsb pdb:5HQ7|rcsb pdb:5I80|rcsb pdb:5I88|rcsb pdb:5IGK|rcsb pdb:5JWM|rcsb pdb:5KDH|rcsb pdb:5KHM|rcsb pdb:5KJ0|rcsb pdb:5KU3|rcsb pdb:5LJ1|rcsb pdb:5LJ2|rcsb pdb:5LRQ|rcsb pdb:5LUU|rcsb pdb:5M39|rcsb pdb:5M3A|rcsb pdb:5MKZ|rcsb pdb:5DW2|rcsb pdb:5MLI|rcsb pdb:5N2M|rcsb pdb:5NNC|rcsb pdb:5NND|rcsb pdb:5NNE|rcsb pdb:5NNF|rcsb pdb:5NNG|rcsb pdb:5O97|rcsb pdb:5UES|rcsb pdb:5UET|rcsb pdb:5OVB|rcsb pdb:5OWM|rcsb pdb:5UEU|rcsb pdb:5UEV|rcsb pdb:5UEX|rcsb pdb:5UEY|rcsb pdb:5UEZ|rcsb pdb:5OWW|rcsb pdb:5UF0|rcsb pdb:5ULA|rcsb pdb:5UOO|rcsb pdb:5UVS|rcsb pdb:5UVT|rcsb pdb:5UVU|rcsb pdb:5UVV|rcsb pdb:5UVW|rcsb pdb:5T35|rcsb pdb:5TI2|rcsb pdb:5TI3|rcsb pdb:5TI4|rcsb pdb:5TI5|rcsb pdb:5TI6|rcsb pdb:5TI7|rcsb pdb:5U28|rcsb pdb:5U2C|rcsb pdb:5U2E|rcsb pdb:5U2F|rcsb pdb:5UVX|rcsb pdb:5UVY|rcsb pdb:5UVZ|rcsb pdb:5V67|rcsb pdb:5VBO|rcsb pdb:5VBP|rcsb pdb:5UEO|rcsb pdb:5VOM|rcsb pdb:5VZS|rcsb pdb:5W55|rcsb pdb:5WA5|rcsb pdb:5WMA|rcsb pdb:5WMD|rcsb pdb:5WMG|rcsb pdb:5WUU|rcsb pdb:5UEP|rcsb pdb:5XHY|rcsb pdb:5UEQ|rcsb pdb:5XI2|rcsb pdb:5XI3|rcsb pdb:5UER|rcsb pdb:5XI4|rcsb pdb:5Y1Y|rcsb pdb:5Y8C|rcsb pdb:5Y8W|rcsb pdb:5Y8Y|rcsb pdb:5Y8Z|rcsb pdb:6VIW|rcsb pdb:6VIX|rcsb pdb:6VIZ|ensembl:ENSP00000263377|ensembl:ENST00000360016|ensembl:ENSP00000353112|ensembl:ENST00000371835|ensembl:ENSP00000360901|ensembl:ENSP00000506350|rcsb pdb:7A9U|rcsb pdb:7AJN|rcsb pdb:7C2Z|rcsb pdb:7C6P|rcsb pdb:7JKX|rcsb pdb:7KHH|rcsb pdb:7KHL|rcsb pdb:7MCF|reactome:R-HSA-9679191|rcsb pdb:6ZF9|rcsb pdb:6VUC|rcsb pdb:6VUF|rcsb pdb:6VUJ|rcsb pdb:6WGX|rcsb pdb:6WW8|rcsb pdb:6X7B|rcsb pdb:6X7C|rcsb pdb:6X7D|rcsb pdb:6XUZ|rcsb pdb:6XV3|rcsb pdb:6XV7|rcsb pdb:6XVC|rcsb pdb:6YIN|rcsb pdb:6YQN|rcsb pdb:6YQO|rcsb pdb:6YQP|rcsb pdb:6YQZ|rcsb pdb:6Z7G|rcsb pdb:6Z7L|rcsb pdb:6Z7M|rcsb pdb:6ZB3|rcsb pdb:6ZCI|rcsb pdb:6ZED|rcsb pdb:6ZEL|rcsb pdb:6VUB|refseq:NP_001317313.1|refseq:XP_011526156.1|refseq:XP_011526158.1|dip:DIP-39776N refseq:NP_001889.2|ensembl:ENSG00000170373(gene)|ensembl:ENST00000304749(transcript)|ensembl:ENST00000398402(transcript)|go:"GO:0001580"(detection of chemical stimulus involved in sensory perception of bitter taste)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR018073|mint:P01037 - - comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:tzQWCG/IwJWaOJ7XO+pXHkPVg+w9606 rogid:Ex6G/NAuwbF8h/4r104dm89B36M9606 rigid:K2edVBg9TqAqUXEY6y1Hf+1vwIs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60885 uniprotkb:P02814 intact:EBI-723869|uniprotkb:O60433|uniprotkb:Q86YS8|uniprotkb:Q96PD3|intact:EBI-28968271|ensembl:ENSP00000263377|ensembl:ENSP00000506350|uniprotkb:Q4G0X8 intact:EBI-738612|uniprotkb:Q9UBN0|uniprotkb:Q9UCT0|uniprotkb:B7ZMG7|ensembl:ENSP00000302400|ensembl:ENSP00000423138 psi-mi:brd4_human(display_long)|uniprotkb:Protein HUNK1(gene name synonym)|uniprotkb:BRD4(gene name)|psi-mi:BRD4(display_short)|uniprotkb:HUNK1(gene name synonym) psi-mi:smr3b_human(display_long)|uniprotkb:SMR3B(gene name)|psi-mi:SMR3B(display_short)|uniprotkb:PBII(gene name synonym)|uniprotkb:PRL3(gene name synonym)|uniprotkb:Proline-rich protein 3(gene name synonym)|uniprotkb:Proline-rich peptide P-B(gene name synonym)|uniprotkb:PROL3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476724|imex:IM-26985-307 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055114.1|refseq:NP_490597.1|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|ensembl:ENSG00000141867(gene)|ensembl:ENST00000263377(transcript)|ensembl:ENST00000679869(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0019899"(enzyme binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:1901407"(regulation of phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:2000002"(negative regulation of DNA damage checkpoint)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR001487(Bromodomain)|interpro:IPR018359|interpro:IPR027353|interpro:IPR031354|interpro:IPR036427|interpro:IPR038336|interpro:IPR043508|interpro:IPR043509|mint:O60885|rcsb pdb:2I8N|rcsb pdb:2LSP|rcsb pdb:2MJV|rcsb pdb:2N3K|rcsb pdb:2NCZ|rcsb pdb:2ND0|rcsb pdb:2ND1|rcsb pdb:2NNU|rcsb pdb:2OSS|rcsb pdb:2OUO|rcsb pdb:2YEL|rcsb pdb:2YEM|rcsb pdb:3MXF|rcsb pdb:5Y93|rcsb pdb:5Y94|rcsb pdb:5YOU|rcsb pdb:5YOV|rcsb pdb:5YQX|rcsb pdb:5Z1R|rcsb pdb:5Z1S|rcsb pdb:5Z1T|rcsb pdb:5Z5T|rcsb pdb:5Z5U|rcsb pdb:5Z5V|rcsb pdb:5Z8G|rcsb pdb:5Z8R|rcsb pdb:5Z8Z|rcsb pdb:5Z90|rcsb pdb:5Z9C|rcsb pdb:5Z9K|rcsb pdb:6AFR|rcsb pdb:6AJV|rcsb pdb:6AJW|rcsb pdb:6AJX|rcsb pdb:6AJY|rcsb pdb:6AJZ|rcsb pdb:6BN7|rcsb pdb:6BN8|rcsb pdb:6BN9|rcsb pdb:6BNB|rcsb pdb:6BNH|rcsb pdb:6BOY|rcsb pdb:6C7Q|rcsb pdb:6C7R|rcsb pdb:6CD4|rcsb pdb:6CD5|rcsb pdb:6CIS|rcsb pdb:6CIY|rcsb pdb:6CJ1|rcsb pdb:6CJ2|rcsb pdb:6CKR|rcsb pdb:6CKS|rcsb pdb:6CZU|rcsb pdb:6CZV|rcsb pdb:6DJC|rcsb pdb:6DL2|rcsb pdb:6DMJ|rcsb pdb:6DML|rcsb pdb:6DNE|rcsb pdb:6DUV|rcsb pdb:6FFD|rcsb pdb:6FNX|rcsb pdb:6FO5|rcsb pdb:6E4A|rcsb pdb:6FSY|rcsb pdb:6FT3|rcsb pdb:6FT4|rcsb pdb:6G0D|rcsb pdb:6G0E|rcsb pdb:6G0F|rcsb pdb:6G0G|rcsb pdb:6G0H|rcsb pdb:6G0O|rcsb pdb:6G0P|rcsb pdb:6G0Q|rcsb pdb:6G0R|rcsb pdb:6G0S|rcsb pdb:6HDQ|rcsb pdb:6HOV|rcsb pdb:6I7X|rcsb pdb:6I7Y|rcsb pdb:6IN1|rcsb pdb:6JI3|rcsb pdb:6JI4|rcsb pdb:6JI5|rcsb pdb:6JJ3|rcsb pdb:6JJ5|rcsb pdb:6JJ6|rcsb pdb:6JJB|rcsb pdb:6KEC|rcsb pdb:6KED|rcsb pdb:6KEE|rcsb pdb:6KEF|rcsb pdb:6KEG|rcsb pdb:6KEH|rcsb pdb:6KEI|rcsb pdb:6KEJ|rcsb pdb:6KEK|rcsb pdb:6KO2|rcsb pdb:6SB8|rcsb pdb:6SE4|rcsb pdb:6SIS|rcsb pdb:6LG4|rcsb pdb:6SWN|rcsb pdb:6SWQ|rcsb pdb:6TPX|rcsb pdb:6TPY|rcsb pdb:6TPZ|rcsb pdb:6U0D|rcsb pdb:6U6K|rcsb pdb:6U6L|rcsb pdb:6U72|rcsb pdb:6U74|rcsb pdb:6U8G|rcsb pdb:6U8I|rcsb pdb:6U8M|rcsb pdb:6ULS|rcsb pdb:6ULV|rcsb pdb:6UVJ|rcsb pdb:6UVM|rcsb pdb:6UWU|rcsb pdb:6UWX|rcsb pdb:6V0U|rcsb pdb:6V1K|rcsb pdb:6V1L|rcsb pdb:6V1U|rcsb pdb:3SVF|rcsb pdb:3SVG|rcsb pdb:3U5J|rcsb pdb:3U5K|rcsb pdb:3U5L|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3ZYU|rcsb pdb:4A9L|rcsb pdb:4BJX|rcsb pdb:4BW1|rcsb pdb:4BW2|rcsb pdb:4BW3|rcsb pdb:4BW4|rcsb pdb:4C66|rcsb pdb:4C67|rcsb pdb:3P5O|rcsb pdb:4CFK|rcsb pdb:4CFL|rcsb pdb:4CL9|rcsb pdb:6LG6|rcsb pdb:6LG7|rcsb pdb:6LG8|rcsb pdb:6LG9|rcsb pdb:6LIH|rcsb pdb:6LIM|rcsb pdb:6MAU|rcsb pdb:6MH1|rcsb pdb:6MH7|rcsb pdb:6MNL|rcsb pdb:6P05|rcsb pdb:6PRT|rcsb pdb:6PS9|rcsb pdb:6PSB|rcsb pdb:6Q3Y|rcsb pdb:6LG5|rcsb pdb:6Q3Z|rcsb pdb:6RWJ|rcsb pdb:6S25|rcsb pdb:6S4B|rcsb pdb:6S6K|rcsb pdb:6SA2|rcsb pdb:6SA3|rcsb pdb:6SAH|rcsb pdb:6SAJ|rcsb pdb:4DON|rcsb pdb:4E96|rcsb pdb:4F3I|rcsb pdb:4GPJ|rcsb pdb:4HBV|rcsb pdb:4HBW|rcsb pdb:4HBX|rcsb pdb:4HBY|rcsb pdb:4HXK|rcsb pdb:4HXL|rcsb pdb:4HXM|rcsb pdb:4HXN|rcsb pdb:4HXO|rcsb pdb:4HXP|rcsb pdb:4HXR|rcsb pdb:4HXS|rcsb pdb:4IOO|rcsb pdb:4IOQ|rcsb pdb:4IOR|rcsb pdb:4J0R|rcsb pdb:4J0S|rcsb pdb:4J3I|rcsb pdb:4CLB|rcsb pdb:4KV1|rcsb pdb:4KV4|rcsb pdb:4LR6|rcsb pdb:4LRG|rcsb pdb:4LYI|rcsb pdb:4LYS|rcsb pdb:4LYW|rcsb pdb:4LZR|rcsb pdb:4LZS|rcsb pdb:4MEN|rcsb pdb:4MEO|rcsb pdb:4MEP|rcsb pdb:4MEQ|rcsb pdb:4MR3|rcsb pdb:4MR4|rcsb pdb:4NQM|rcsb pdb:4NR8|rcsb pdb:4NUC|rcsb pdb:4NUD|rcsb pdb:4NUE|rcsb pdb:4O70|rcsb pdb:4O71|rcsb pdb:4O72|rcsb pdb:4O74|rcsb pdb:4O75|rcsb pdb:4O76|rcsb pdb:4O77|rcsb pdb:4O78|rcsb pdb:4O7A|rcsb pdb:4O7B|rcsb pdb:4O7C|rcsb pdb:4O7E|rcsb pdb:4O7F|rcsb pdb:4OGI|rcsb pdb:4OGJ|rcsb pdb:4PCE|rcsb pdb:4PCI|rcsb pdb:4PS5|rcsb pdb:4QR3|rcsb pdb:4QR4|rcsb pdb:4QR5|rcsb pdb:4QZS|rcsb pdb:4UIX|rcsb pdb:4UIY|rcsb pdb:4UIZ|rcsb pdb:4UYD|rcsb pdb:4WHW|rcsb pdb:4WIV|rcsb pdb:4X2I|rcsb pdb:4XY9|rcsb pdb:4XYA|rcsb pdb:4YH3|rcsb pdb:4YH4|rcsb pdb:4Z1Q|rcsb pdb:4QB3|rcsb pdb:4Z1S|rcsb pdb:4Z93|rcsb pdb:4ZC9|rcsb pdb:4ZW1|rcsb pdb:5ACY|rcsb pdb:5AD2|rcsb pdb:5AD3|rcsb pdb:5BT4|rcsb pdb:5CFW|rcsb pdb:5COI|rcsb pdb:5CP5|rcsb pdb:5CPE|rcsb pdb:5CQT|rcsb pdb:5A5S|rcsb pdb:5CRM|rcsb pdb:5CRZ|rcsb pdb:5CS8|rcsb pdb:5CTL|rcsb pdb:5CY9|rcsb pdb:5D0C|rcsb pdb:5D24|rcsb pdb:5D25|rcsb pdb:5D26|rcsb pdb:5D3H|rcsb pdb:5D3J|rcsb pdb:5D3L|rcsb pdb:5D3N|rcsb pdb:5D3P|rcsb pdb:5A85|rcsb pdb:5D3R|rcsb pdb:5D3S|rcsb pdb:5D3T|rcsb pdb:5DLX|rcsb pdb:5DLZ|rcsb pdb:5DX4|rcsb pdb:5E0R|rcsb pdb:5EGU|rcsb pdb:5EI4|rcsb pdb:5EIS|rcsb pdb:5F5Z|rcsb pdb:5F60|rcsb pdb:5F61|rcsb pdb:5F62|rcsb pdb:5F63|rcsb pdb:5FBX|rcsb pdb:5H21|rcsb pdb:5HCL|rcsb pdb:5HLS|rcsb pdb:5HM0|rcsb pdb:5HQ5|rcsb pdb:5HQ6|rcsb pdb:5HQ7|rcsb pdb:5I80|rcsb pdb:5I88|rcsb pdb:5IGK|rcsb pdb:5JWM|rcsb pdb:5KDH|rcsb pdb:5KHM|rcsb pdb:5KJ0|rcsb pdb:5KU3|rcsb pdb:5LJ1|rcsb pdb:5LJ2|rcsb pdb:5LRQ|rcsb pdb:5LUU|rcsb pdb:5M39|rcsb pdb:5M3A|rcsb pdb:5MKZ|rcsb pdb:5DW2|rcsb pdb:5MLI|rcsb pdb:5N2M|rcsb pdb:5NNC|rcsb pdb:5NND|rcsb pdb:5NNE|rcsb pdb:5NNF|rcsb pdb:5NNG|rcsb pdb:5O97|rcsb pdb:5UES|rcsb pdb:5UET|rcsb pdb:5OVB|rcsb pdb:5OWM|rcsb pdb:5UEU|rcsb pdb:5UEV|rcsb pdb:5UEX|rcsb pdb:5UEY|rcsb pdb:5UEZ|rcsb pdb:5OWW|rcsb pdb:5UF0|rcsb pdb:5ULA|rcsb pdb:5UOO|rcsb pdb:5UVS|rcsb pdb:5UVT|rcsb pdb:5UVU|rcsb pdb:5UVV|rcsb pdb:5UVW|rcsb pdb:5T35|rcsb pdb:5TI2|rcsb pdb:5TI3|rcsb pdb:5TI4|rcsb pdb:5TI5|rcsb pdb:5TI6|rcsb pdb:5TI7|rcsb pdb:5U28|rcsb pdb:5U2C|rcsb pdb:5U2E|rcsb pdb:5U2F|rcsb pdb:5UVX|rcsb pdb:5UVY|rcsb pdb:5UVZ|rcsb pdb:5V67|rcsb pdb:5VBO|rcsb pdb:5VBP|rcsb pdb:5UEO|rcsb pdb:5VOM|rcsb pdb:5VZS|rcsb pdb:5W55|rcsb pdb:5WA5|rcsb pdb:5WMA|rcsb pdb:5WMD|rcsb pdb:5WMG|rcsb pdb:5WUU|rcsb pdb:5UEP|rcsb pdb:5XHY|rcsb pdb:5UEQ|rcsb pdb:5XI2|rcsb pdb:5XI3|rcsb pdb:5UER|rcsb pdb:5XI4|rcsb pdb:5Y1Y|rcsb pdb:5Y8C|rcsb pdb:5Y8W|rcsb pdb:5Y8Y|rcsb pdb:5Y8Z|rcsb pdb:6VIW|rcsb pdb:6VIX|rcsb pdb:6VIZ|ensembl:ENSP00000263377|ensembl:ENST00000360016|ensembl:ENSP00000353112|ensembl:ENST00000371835|ensembl:ENSP00000360901|ensembl:ENSP00000506350|rcsb pdb:7A9U|rcsb pdb:7AJN|rcsb pdb:7C2Z|rcsb pdb:7C6P|rcsb pdb:7JKX|rcsb pdb:7KHH|rcsb pdb:7KHL|rcsb pdb:7MCF|reactome:R-HSA-9679191|rcsb pdb:6ZF9|rcsb pdb:6VUC|rcsb pdb:6VUF|rcsb pdb:6VUJ|rcsb pdb:6WGX|rcsb pdb:6WW8|rcsb pdb:6X7B|rcsb pdb:6X7C|rcsb pdb:6X7D|rcsb pdb:6XUZ|rcsb pdb:6XV3|rcsb pdb:6XV7|rcsb pdb:6XVC|rcsb pdb:6YIN|rcsb pdb:6YQN|rcsb pdb:6YQO|rcsb pdb:6YQP|rcsb pdb:6YQZ|rcsb pdb:6Z7G|rcsb pdb:6Z7L|rcsb pdb:6Z7M|rcsb pdb:6ZB3|rcsb pdb:6ZCI|rcsb pdb:6ZED|rcsb pdb:6ZEL|rcsb pdb:6VUB|refseq:NP_001317313.1|refseq:XP_011526156.1|refseq:XP_011526158.1|dip:DIP-39776N refseq:NP_006676.1|ensembl:ENSG00000171201(gene)|ensembl:ENST00000304915(transcript)|ensembl:ENST00000504825(transcript)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0070062"(extracellular exosome)|interpro:IPR026288|mint:P02814 - - comment:"author score: 34" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:tzQWCG/IwJWaOJ7XO+pXHkPVg+w9606 rogid:WJ7Ag6lcBGK16pBo7LaEWJ1hydg9606 rigid:K2edVBg9TqAqUXEY6y1Hf+1vwIs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60885 uniprotkb:Q96QE3 intact:EBI-723869|uniprotkb:O60433|uniprotkb:Q86YS8|uniprotkb:Q96PD3|intact:EBI-28968271|ensembl:ENSP00000263377|ensembl:ENSP00000506350|uniprotkb:Q4G0X8 intact:EBI-10980241|ensembl:ENSP00000313171|uniprotkb:Q05DH0|uniprotkb:Q9H9I1|uniprotkb:Q69YR6 psi-mi:brd4_human(display_long)|uniprotkb:Protein HUNK1(gene name synonym)|uniprotkb:BRD4(gene name)|psi-mi:BRD4(display_short)|uniprotkb:HUNK1(gene name synonym) psi-mi:atad5_human(display_long)|uniprotkb:ATAD5(gene name)|psi-mi:ATAD5(display_short)|uniprotkb:C17orf41(gene name synonym)|uniprotkb:Chromosome fragility-associated gene 1 protein(gene name synonym)|uniprotkb:FRAG1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476724|imex:IM-26985-307 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055114.1|refseq:NP_490597.1|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|ensembl:ENSG00000141867(gene)|ensembl:ENST00000263377(transcript)|ensembl:ENST00000679869(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0019899"(enzyme binding)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:1901407"(regulation of phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:2000002"(negative regulation of DNA damage checkpoint)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR001487(Bromodomain)|interpro:IPR018359|interpro:IPR027353|interpro:IPR031354|interpro:IPR036427|interpro:IPR038336|interpro:IPR043508|interpro:IPR043509|mint:O60885|rcsb pdb:2I8N|rcsb pdb:2LSP|rcsb pdb:2MJV|rcsb pdb:2N3K|rcsb pdb:2NCZ|rcsb pdb:2ND0|rcsb pdb:2ND1|rcsb pdb:2NNU|rcsb pdb:2OSS|rcsb pdb:2OUO|rcsb pdb:2YEL|rcsb pdb:2YEM|rcsb pdb:3MXF|rcsb pdb:5Y93|rcsb pdb:5Y94|rcsb pdb:5YOU|rcsb pdb:5YOV|rcsb pdb:5YQX|rcsb pdb:5Z1R|rcsb pdb:5Z1S|rcsb pdb:5Z1T|rcsb pdb:5Z5T|rcsb pdb:5Z5U|rcsb pdb:5Z5V|rcsb pdb:5Z8G|rcsb pdb:5Z8R|rcsb pdb:5Z8Z|rcsb pdb:5Z90|rcsb pdb:5Z9C|rcsb pdb:5Z9K|rcsb pdb:6AFR|rcsb pdb:6AJV|rcsb pdb:6AJW|rcsb pdb:6AJX|rcsb pdb:6AJY|rcsb pdb:6AJZ|rcsb pdb:6BN7|rcsb pdb:6BN8|rcsb pdb:6BN9|rcsb pdb:6BNB|rcsb pdb:6BNH|rcsb pdb:6BOY|rcsb pdb:6C7Q|rcsb pdb:6C7R|rcsb pdb:6CD4|rcsb pdb:6CD5|rcsb pdb:6CIS|rcsb pdb:6CIY|rcsb pdb:6CJ1|rcsb pdb:6CJ2|rcsb pdb:6CKR|rcsb pdb:6CKS|rcsb pdb:6CZU|rcsb pdb:6CZV|rcsb pdb:6DJC|rcsb pdb:6DL2|rcsb pdb:6DMJ|rcsb pdb:6DML|rcsb pdb:6DNE|rcsb pdb:6DUV|rcsb pdb:6FFD|rcsb pdb:6FNX|rcsb pdb:6FO5|rcsb pdb:6E4A|rcsb pdb:6FSY|rcsb pdb:6FT3|rcsb pdb:6FT4|rcsb pdb:6G0D|rcsb pdb:6G0E|rcsb pdb:6G0F|rcsb pdb:6G0G|rcsb pdb:6G0H|rcsb pdb:6G0O|rcsb pdb:6G0P|rcsb pdb:6G0Q|rcsb pdb:6G0R|rcsb pdb:6G0S|rcsb pdb:6HDQ|rcsb pdb:6HOV|rcsb pdb:6I7X|rcsb pdb:6I7Y|rcsb pdb:6IN1|rcsb pdb:6JI3|rcsb pdb:6JI4|rcsb pdb:6JI5|rcsb pdb:6JJ3|rcsb pdb:6JJ5|rcsb pdb:6JJ6|rcsb pdb:6JJB|rcsb pdb:6KEC|rcsb pdb:6KED|rcsb pdb:6KEE|rcsb pdb:6KEF|rcsb pdb:6KEG|rcsb pdb:6KEH|rcsb pdb:6KEI|rcsb pdb:6KEJ|rcsb pdb:6KEK|rcsb pdb:6KO2|rcsb pdb:6SB8|rcsb pdb:6SE4|rcsb pdb:6SIS|rcsb pdb:6LG4|rcsb pdb:6SWN|rcsb pdb:6SWQ|rcsb pdb:6TPX|rcsb pdb:6TPY|rcsb pdb:6TPZ|rcsb pdb:6U0D|rcsb pdb:6U6K|rcsb pdb:6U6L|rcsb pdb:6U72|rcsb pdb:6U74|rcsb pdb:6U8G|rcsb pdb:6U8I|rcsb pdb:6U8M|rcsb pdb:6ULS|rcsb pdb:6ULV|rcsb pdb:6UVJ|rcsb pdb:6UVM|rcsb pdb:6UWU|rcsb pdb:6UWX|rcsb pdb:6V0U|rcsb pdb:6V1K|rcsb pdb:6V1L|rcsb pdb:6V1U|rcsb pdb:3SVF|rcsb pdb:3SVG|rcsb pdb:3U5J|rcsb pdb:3U5K|rcsb pdb:3U5L|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3ZYU|rcsb pdb:4A9L|rcsb pdb:4BJX|rcsb pdb:4BW1|rcsb pdb:4BW2|rcsb pdb:4BW3|rcsb pdb:4BW4|rcsb pdb:4C66|rcsb pdb:4C67|rcsb pdb:3P5O|rcsb pdb:4CFK|rcsb pdb:4CFL|rcsb pdb:4CL9|rcsb pdb:6LG6|rcsb pdb:6LG7|rcsb pdb:6LG8|rcsb pdb:6LG9|rcsb pdb:6LIH|rcsb pdb:6LIM|rcsb pdb:6MAU|rcsb pdb:6MH1|rcsb pdb:6MH7|rcsb pdb:6MNL|rcsb pdb:6P05|rcsb pdb:6PRT|rcsb pdb:6PS9|rcsb pdb:6PSB|rcsb pdb:6Q3Y|rcsb pdb:6LG5|rcsb pdb:6Q3Z|rcsb pdb:6RWJ|rcsb pdb:6S25|rcsb pdb:6S4B|rcsb pdb:6S6K|rcsb pdb:6SA2|rcsb pdb:6SA3|rcsb pdb:6SAH|rcsb pdb:6SAJ|rcsb pdb:4DON|rcsb pdb:4E96|rcsb pdb:4F3I|rcsb pdb:4GPJ|rcsb pdb:4HBV|rcsb pdb:4HBW|rcsb pdb:4HBX|rcsb pdb:4HBY|rcsb pdb:4HXK|rcsb pdb:4HXL|rcsb pdb:4HXM|rcsb pdb:4HXN|rcsb pdb:4HXO|rcsb pdb:4HXP|rcsb pdb:4HXR|rcsb pdb:4HXS|rcsb pdb:4IOO|rcsb pdb:4IOQ|rcsb pdb:4IOR|rcsb pdb:4J0R|rcsb pdb:4J0S|rcsb pdb:4J3I|rcsb pdb:4CLB|rcsb pdb:4KV1|rcsb pdb:4KV4|rcsb pdb:4LR6|rcsb pdb:4LRG|rcsb pdb:4LYI|rcsb pdb:4LYS|rcsb pdb:4LYW|rcsb pdb:4LZR|rcsb pdb:4LZS|rcsb pdb:4MEN|rcsb pdb:4MEO|rcsb pdb:4MEP|rcsb pdb:4MEQ|rcsb pdb:4MR3|rcsb pdb:4MR4|rcsb pdb:4NQM|rcsb pdb:4NR8|rcsb pdb:4NUC|rcsb pdb:4NUD|rcsb pdb:4NUE|rcsb pdb:4O70|rcsb pdb:4O71|rcsb pdb:4O72|rcsb pdb:4O74|rcsb pdb:4O75|rcsb pdb:4O76|rcsb pdb:4O77|rcsb pdb:4O78|rcsb pdb:4O7A|rcsb pdb:4O7B|rcsb pdb:4O7C|rcsb pdb:4O7E|rcsb pdb:4O7F|rcsb pdb:4OGI|rcsb pdb:4OGJ|rcsb pdb:4PCE|rcsb pdb:4PCI|rcsb pdb:4PS5|rcsb pdb:4QR3|rcsb pdb:4QR4|rcsb pdb:4QR5|rcsb pdb:4QZS|rcsb pdb:4UIX|rcsb pdb:4UIY|rcsb pdb:4UIZ|rcsb pdb:4UYD|rcsb pdb:4WHW|rcsb pdb:4WIV|rcsb pdb:4X2I|rcsb pdb:4XY9|rcsb pdb:4XYA|rcsb pdb:4YH3|rcsb pdb:4YH4|rcsb pdb:4Z1Q|rcsb pdb:4QB3|rcsb pdb:4Z1S|rcsb pdb:4Z93|rcsb pdb:4ZC9|rcsb pdb:4ZW1|rcsb pdb:5ACY|rcsb pdb:5AD2|rcsb pdb:5AD3|rcsb pdb:5BT4|rcsb pdb:5CFW|rcsb pdb:5COI|rcsb pdb:5CP5|rcsb pdb:5CPE|rcsb pdb:5CQT|rcsb pdb:5A5S|rcsb pdb:5CRM|rcsb pdb:5CRZ|rcsb pdb:5CS8|rcsb pdb:5CTL|rcsb pdb:5CY9|rcsb pdb:5D0C|rcsb pdb:5D24|rcsb pdb:5D25|rcsb pdb:5D26|rcsb pdb:5D3H|rcsb pdb:5D3J|rcsb pdb:5D3L|rcsb pdb:5D3N|rcsb pdb:5D3P|rcsb pdb:5A85|rcsb pdb:5D3R|rcsb pdb:5D3S|rcsb pdb:5D3T|rcsb pdb:5DLX|rcsb pdb:5DLZ|rcsb pdb:5DX4|rcsb pdb:5E0R|rcsb pdb:5EGU|rcsb pdb:5EI4|rcsb pdb:5EIS|rcsb pdb:5F5Z|rcsb pdb:5F60|rcsb pdb:5F61|rcsb pdb:5F62|rcsb pdb:5F63|rcsb pdb:5FBX|rcsb pdb:5H21|rcsb pdb:5HCL|rcsb pdb:5HLS|rcsb pdb:5HM0|rcsb pdb:5HQ5|rcsb pdb:5HQ6|rcsb pdb:5HQ7|rcsb pdb:5I80|rcsb pdb:5I88|rcsb pdb:5IGK|rcsb pdb:5JWM|rcsb pdb:5KDH|rcsb pdb:5KHM|rcsb pdb:5KJ0|rcsb pdb:5KU3|rcsb pdb:5LJ1|rcsb pdb:5LJ2|rcsb pdb:5LRQ|rcsb pdb:5LUU|rcsb pdb:5M39|rcsb pdb:5M3A|rcsb pdb:5MKZ|rcsb pdb:5DW2|rcsb pdb:5MLI|rcsb pdb:5N2M|rcsb pdb:5NNC|rcsb pdb:5NND|rcsb pdb:5NNE|rcsb pdb:5NNF|rcsb pdb:5NNG|rcsb pdb:5O97|rcsb pdb:5UES|rcsb pdb:5UET|rcsb pdb:5OVB|rcsb pdb:5OWM|rcsb pdb:5UEU|rcsb pdb:5UEV|rcsb pdb:5UEX|rcsb pdb:5UEY|rcsb pdb:5UEZ|rcsb pdb:5OWW|rcsb pdb:5UF0|rcsb pdb:5ULA|rcsb pdb:5UOO|rcsb pdb:5UVS|rcsb pdb:5UVT|rcsb pdb:5UVU|rcsb pdb:5UVV|rcsb pdb:5UVW|rcsb pdb:5T35|rcsb pdb:5TI2|rcsb pdb:5TI3|rcsb pdb:5TI4|rcsb pdb:5TI5|rcsb pdb:5TI6|rcsb pdb:5TI7|rcsb pdb:5U28|rcsb pdb:5U2C|rcsb pdb:5U2E|rcsb pdb:5U2F|rcsb pdb:5UVX|rcsb pdb:5UVY|rcsb pdb:5UVZ|rcsb pdb:5V67|rcsb pdb:5VBO|rcsb pdb:5VBP|rcsb pdb:5UEO|rcsb pdb:5VOM|rcsb pdb:5VZS|rcsb pdb:5W55|rcsb pdb:5WA5|rcsb pdb:5WMA|rcsb pdb:5WMD|rcsb pdb:5WMG|rcsb pdb:5WUU|rcsb pdb:5UEP|rcsb pdb:5XHY|rcsb pdb:5UEQ|rcsb pdb:5XI2|rcsb pdb:5XI3|rcsb pdb:5UER|rcsb pdb:5XI4|rcsb pdb:5Y1Y|rcsb pdb:5Y8C|rcsb pdb:5Y8W|rcsb pdb:5Y8Y|rcsb pdb:5Y8Z|rcsb pdb:6VIW|rcsb pdb:6VIX|rcsb pdb:6VIZ|ensembl:ENSP00000263377|ensembl:ENST00000360016|ensembl:ENSP00000353112|ensembl:ENST00000371835|ensembl:ENSP00000360901|ensembl:ENSP00000506350|rcsb pdb:7A9U|rcsb pdb:7AJN|rcsb pdb:7C2Z|rcsb pdb:7C6P|rcsb pdb:7JKX|rcsb pdb:7KHH|rcsb pdb:7KHL|rcsb pdb:7MCF|reactome:R-HSA-9679191|rcsb pdb:6ZF9|rcsb pdb:6VUC|rcsb pdb:6VUF|rcsb pdb:6VUJ|rcsb pdb:6WGX|rcsb pdb:6WW8|rcsb pdb:6X7B|rcsb pdb:6X7C|rcsb pdb:6X7D|rcsb pdb:6XUZ|rcsb pdb:6XV3|rcsb pdb:6XV7|rcsb pdb:6XVC|rcsb pdb:6YIN|rcsb pdb:6YQN|rcsb pdb:6YQO|rcsb pdb:6YQP|rcsb pdb:6YQZ|rcsb pdb:6Z7G|rcsb pdb:6Z7L|rcsb pdb:6Z7M|rcsb pdb:6ZB3|rcsb pdb:6ZCI|rcsb pdb:6ZED|rcsb pdb:6ZEL|rcsb pdb:6VUB|refseq:NP_001317313.1|refseq:XP_011526156.1|refseq:XP_011526158.1|dip:DIP-39776N refseq:NP_079133.3|ensembl:ENSG00000176208(gene)|ensembl:ENST00000321990(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031391"(Elg1 RFC-like complex)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0061860"(DNA clamp unloader activity)|go:"GO:0090618"(DNA clamp unloading)|go:"GO:1902751"(positive regulation of cell cycle G2/M phase transition)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR027417|mint:Q96QE3|dip:DIP-62118N - - comment:"author score: 44" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:tzQWCG/IwJWaOJ7XO+pXHkPVg+w9606 rogid:RykTLq8koh3X5KGZI8THhWttHcE9606 rigid:K2edVBg9TqAqUXEY6y1Hf+1vwIs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q7Z3K3 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-1389308|uniprotkb:O75049|uniprotkb:Q5SZS2|uniprotkb:Q5SZS3|uniprotkb:Q5SZS4|uniprotkb:Q8TDZ7|uniprotkb:Q9Y4X7|uniprotkb:Q3LIC4|uniprotkb:Q5SZS1|intact:EBI-2560449|intact:EBI-11742841|uniprotkb:B4DTP8|uniprotkb:B4DYL9|uniprotkb:B7ZBY5|uniprotkb:E9PM80|intact:EBI-14072025|intact:EBI-17205119|intact:EBI-22321456|intact:EBI-12748249|intact:EBI-16429759|ensembl:ENSP00000271715 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:pogz_human(display_long)|uniprotkb:POGZ(gene name)|psi-mi:POGZ(display_short)|uniprotkb:KIAA0461(gene name synonym)|uniprotkb:Nbla00003(orf name)|uniprotkb:SUHW5(gene name synonym)|uniprotkb:ZNF280E(gene name synonym)|uniprotkb:ZNF635(gene name synonym)|uniprotkb:Suppressor of hairy wing homolog 5(gene name synonym)|uniprotkb:Zinc finger protein 280E(gene name synonym)|uniprotkb:Zinc finger protein 635(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476790|imex:IM-26985-151 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N refseq:NP_001181866.1|refseq:NP_001181867.1|refseq:NP_055915.2|refseq:NP_665739.3|refseq:NP_997054.1|refseq:XP_016856234.1|refseq:XP_016856235.1|refseq:XP_016856237.1|refseq:XP_016856238.1|refseq:XP_005245056.1|refseq:XP_005245057.1|refseq:XP_005245058.1|refseq:XP_005245062.1|refseq:XP_005245063.1|dip:DIP-38044N|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSG00000143442(gene)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|ensembl:ENST00000271715(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR004875(CENP-B protein)|interpro:IPR006600(Centromere protein B, helix-turn-helix)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q7Z3K3|rcsb pdb:2E72|rcsb pdb:2N3A|rcsb pdb:6EMP - - comment:"author score: 64" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:sCOIY8KsHRQtfcoSA9Tixl9yIsc9606 rigid:urcB5q17tmLzlq6I1n6/60T8rEI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q9H410 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-1001144|uniprotkb:E1P5U9|uniprotkb:Q5JW56|uniprotkb:Q9H8P4|ensembl:ENSP00000362855|ensembl:ENSP00000389810|uniprotkb:Q5JW55|uniprotkb:B4DWT2 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:dsn1_human(display_long)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)|uniprotkb:C20orf172(gene name synonym)|uniprotkb:MIS13(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476790|imex:IM-26985-151 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N refseq:NP_001138789.1|refseq:NP_001138787.1|refseq:NP_001138788.1|refseq:NP_079194.3|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-68877|reactome:R-HSA-9648025|rcsb pdb:5LSK|ensembl:ENSG00000149636(gene)|ensembl:ENST00000373750(transcript)|ensembl:ENST00000426836(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000939"(inner kinetochore)|go:"GO:0001650"(fibrillar center)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0051301"(cell division)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|mint:Q9H410|rcsb pdb:5LSI|rcsb pdb:5LSJ|refseq:NP_001138790.1|refseq:XP_006723939.1 - - comment:"author score: 66" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:cJ0wCtpLS+YkMj83k/SubkpHwuE9606 rigid:urcB5q17tmLzlq6I1n6/60T8rEI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q9H081 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-1001205|uniprotkb:Q96N24|ensembl:ENSP00000370557|ensembl:ENSP00000461252|ensembl:ENSP00000484532 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:mis12_human(display_long)|uniprotkb:MIS12(gene name)|psi-mi:MIS12(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476790|imex:IM-26985-151 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N refseq:NP_001245146.1|refseq:NP_001245147.1|refseq:NP_001245148.1|refseq:NP_001245149.1|refseq:XP_016880522.1|refseq:XP_016880523.1|refseq:XP_016880524.1|refseq:NP_076944.1|ensembl:ENSG00000167842(gene)|ensembl:ENST00000381165(transcript)|ensembl:ENST00000573759(transcript)|ensembl:ENST00000611091(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR008685(Mis12)|mint:Q9H081|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-5663220|refseq:XP_005256854.1 - - comment:"author score: 73" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:1qNMwDq3AYOWnRnPa2u3yt7O4109606 rigid:urcB5q17tmLzlq6I1n6/60T8rEI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:P22531 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-2556846|uniprotkb:Q5T9T4|uniprotkb:Q96RM2|ensembl:ENSP00000357739|ensembl:ENSP00000357740 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:spr2e_human(display_long)|uniprotkb:Small proline-rich protein II(gene name synonym)|uniprotkb:SPRR2E(gene name)|psi-mi:SPRR2E(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476790|imex:IM-26985-151 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N refseq:NP_001019380.2|ensembl:ENSG00000203785(gene)|ensembl:ENST00000368750(transcript)|ensembl:ENST00000368751(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030280"(structural constituent of skin epidermis)|go:"GO:0031424"(keratinization)|interpro:IPR029142|mint:P22531|reactome:R-HSA-6809371 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:Pwemojva9RHkLb7mVmctpxenpf49606 rigid:urcB5q17tmLzlq6I1n6/60T8rEI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q86XI8 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-2682158|ensembl:ENSP00000331363|uniprotkb:A0A087WWL5 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:zswm9_human(display_long)|uniprotkb:ZSWIM9(gene name)|psi-mi:ZSWIM9(display_short)|uniprotkb:C19orf68(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476790|imex:IM-26985-151 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N refseq:NP_955373.3|ensembl:ENSG00000185453(gene)|ensembl:ENST00000328759(transcript)|interpro:IPR040854|mint:Q86XI8|refseq:XP_006723268.1 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:4wOy3iLGFg7lgvbA8nWPUgIgS0w9606 rigid:urcB5q17tmLzlq6I1n6/60T8rEI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q9P0T4 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-745520|uniprotkb:B2RDM6|ensembl:ENSP00000270451|ensembl:ENSP00000466047|ensembl:ENSP00000466564 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:zn581_human(display_long)|uniprotkb:ZNF581(gene name)|psi-mi:ZNF581(display_short)|uniprotkb:HSPC189(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476790|imex:IM-26985-151 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N refseq:NP_057619.1|ensembl:ENSG00000171425(gene)|ensembl:ENST00000270451(transcript)|ensembl:ENST00000587252(transcript)|ensembl:ENST00000588537(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9P0T4|go:"GO:0005634"(nucleus)|refseq:XP_006723303.1|refseq:XP_016882356.1 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:SpE0ZPhcfXB4PnyufoyWq4iNAs89606 rigid:urcB5q17tmLzlq6I1n6/60T8rEI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q13263 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-78139|uniprotkb:O00677|ensembl:ENSP00000253024|uniprotkb:Q7Z632|uniprotkb:Q93040|uniprotkb:Q96IM1 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:tif1b_human(display_long)|uniprotkb:TRIM28(gene name)|psi-mi:TRIM28(display_short)|uniprotkb:KAP1(gene name synonym)|uniprotkb:RNF96(gene name synonym)|uniprotkb:TIF1B(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:Nuclear corepressor KAP-1(gene name synonym)|uniprotkb:KRAB-associated protein 1(gene name synonym)|uniprotkb:KRAB-interacting protein 1(gene name synonym)|uniprotkb:RING finger protein 96(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476790|imex:IM-26985-151 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N ensembl:ENSG00000130726(gene)|ensembl:ENST00000253024(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6QAJ|rcsb pdb:6QU1|reactome:R-HSA-212436|reactome:R-HSA-3899300|reactome:R-HSA-9609690|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q13263|rcsb pdb:1FP0|rcsb pdb:2RO1|rcsb pdb:2YVR|rcsb pdb:6H3A|rcsb pdb:6I9H|refseq:NP_005753.1|dip:DIP-30891N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:/yXCDGKUyyYnArOLyfzx6uPR9QY9606 rigid:urcB5q17tmLzlq6I1n6/60T8rEI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q14202 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-2556139|uniprotkb:O15089|ensembl:ENSP00000322845|uniprotkb:D3DVV3|uniprotkb:Q96E26 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:zmym3_human(display_long)|uniprotkb:DXS6673E(gene name synonym)|uniprotkb:KIAA0385(gene name synonym)|uniprotkb:ZNF261(gene name synonym)|uniprotkb:Zinc finger protein 261(gene name synonym)|uniprotkb:ZMYM3(gene name)|psi-mi:ZMYM3(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476790|imex:IM-26985-151 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N refseq:NP_001164633.1|refseq:NP_005087.1|refseq:NP_963893.1|refseq:XP_011529364.1|ensembl:ENSG00000147130(gene)|ensembl:ENST00000314425(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022604"(regulation of cell morphogenesis)|interpro:IPR010507(Zinc finger, MYM-type)|interpro:IPR011017(TRASH)|interpro:IPR021893|mint:Q14202|refseq:NP_001164634.1|refseq:XP_005262366.1|refseq:XP_005262367.1 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:pNPpauiC3Qk1EB3mevtM9L/+g0A9606 rigid:urcB5q17tmLzlq6I1n6/60T8rEI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:O60281 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-1224010|uniprotkb:Q9H8G3|uniprotkb:Q9H8J4|uniprotkb:Q5W0B2|uniprotkb:Q7Z3L7|intact:EBI-28971048|ensembl:ENSP00000358590 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:zn292_human(display_long)|uniprotkb:ZNF292(gene name)|psi-mi:ZNF292(display_short)|uniprotkb:KIAA0530(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476790|imex:IM-26985-151 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N ensembl:ENSP00000358590|refseq:NP_055836.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|ensembl:ENSG00000188994(gene)|interpro:IPR036236|mint:O60281|rcsb pdb:1X3C|ensembl:ENST00000369577(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus) - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:4Ss6SyxGv1bSjSBhSjquUKutB349606 rigid:urcB5q17tmLzlq6I1n6/60T8rEI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q06587 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476790|imex:IM-26985-151 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rigid:urcB5q17tmLzlq6I1n6/60T8rEI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q09028 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476790|imex:IM-26985-151 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rigid:urcB5q17tmLzlq6I1n6/60T8rEI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q6N043 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-4395404|uniprotkb:A1L495|uniprotkb:B2RMT6|uniprotkb:Q6MZM6|uniprotkb:Q6N085|uniprotkb:Q9H0U5|uniprotkb:Q9HCI8|uniprotkb:Q9NXS0|uniprotkb:Q6P2R6|uniprotkb:Q7Z6J5|intact:EBI-28970145|ensembl:ENSP00000267807 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:z280d_human(display_long)|uniprotkb:ZNF280D(gene name)|psi-mi:ZNF280D(display_short)|uniprotkb:KIAA1584(gene name synonym)|uniprotkb:SUHW4(gene name synonym)|uniprotkb:ZNF634(gene name synonym)|uniprotkb:Suppressor of hairy wing homolog 4(gene name synonym)|uniprotkb:Zinc finger protein 634(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476790|imex:IM-26985-151 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N ensembl:ENSP00000267807|ensembl:ENST00000558067|ensembl:ENSP00000454173|ensembl:ENST00000558320|ensembl:ENSP00000453706|ensembl:ENST00000559237|ensembl:ENSP00000454111|ensembl:ENST00000560002|ensembl:ENSP00000453636|refseq:XP_011520004.1|refseq:NP_001002843.1|refseq:NP_060131.2|refseq:NP_001275517.1|refseq:NP_001002844.1|refseq:NP_001275518.1|refseq:XP_016877833.1|refseq:XP_016877834.1|ensembl:ENSG00000137871(gene)|ensembl:ENST00000267807(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR025243|interpro:IPR036236|mint:Q6N043 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:BYkVW7yPK+LxorbA2quTgne0Txs9606 rigid:urcB5q17tmLzlq6I1n6/60T8rEI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:P06702 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-1055001|uniprotkb:Q6FGA1|uniprotkb:Q9NYM0|uniprotkb:Q9UCJ1|uniprotkb:D3DV36|ensembl:ENSP00000357727 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:s10a9_human(display_long)|uniprotkb:S100 calcium-binding protein A9(gene name synonym)|uniprotkb:Calgranulin-B(gene name synonym)|uniprotkb:Migration inhibitory factor-related protein 14(gene name synonym)|uniprotkb:Leukocyte L1 complex heavy chain(gene name synonym)|uniprotkb:Calprotectin L1H subunit(gene name synonym)|uniprotkb:S100A9(gene name)|psi-mi:S100A9(display_short)|uniprotkb:CAGB(gene name synonym)|uniprotkb:CFAG(gene name synonym)|uniprotkb:MRP14(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476790|imex:IM-26985-151 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N refseq:NP_002956.1|rcsb pdb:1XK4|rcsb pdb:4GGF|rcsb pdb:4XJK|rcsb pdb:5I8N|rcsb pdb:5W1F|rcsb pdb:6DS2|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5668599|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-6799990|ensembl:ENSG00000163220(gene)|ensembl:ENST00000368738(transcript)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035662"(Toll-like receptor 4 binding)|go:"GO:0035821"(modulation of process of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0045113"(regulation of integrin biosynthetic process)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070488"(neutrophil aggregation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|mint:P06702|rcsb pdb:1IRJ|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016209"(antioxidant activity)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0030054"(cell junction)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032119"(sequestering of zinc ion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035425"(autocrine signaling)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|dip:DIP-1166N - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:IGnX4DSnv8xMr5pY4T7X7vYos5A9606 rigid:urcB5q17tmLzlq6I1n6/60T8rEI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:P61964 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476790|imex:IM-26985-151 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rigid:urcB5q17tmLzlq6I1n6/60T8rEI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:P06899 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-6150252|uniprotkb:B2R4J4|uniprotkb:O60816|ensembl:ENSP00000342886|ensembl:ENSP00000476136 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:h2b1j_human(display_long)|uniprotkb:H2BC11(gene name)|psi-mi:H2BC11(display_short)|uniprotkb:H2BFR(gene name synonym)|uniprotkb:HIST1H2BJ(gene name synonym)|uniprotkb:Histone H2B.1(gene name synonym)|uniprotkb:Histone H2B.r(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476790|imex:IM-26985-151 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N refseq:NP_066402.2|dip:DIP-421N|ensembl:ENSG00000124635(gene)|ensembl:ENST00000339812(transcript)|ensembl:ENST00000607124(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P06899|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WAA|rcsb pdb:3WTP|rcsb pdb:4CAY|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5FUG|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5VEY|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6JXD|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6YOV|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7K5X|rcsb pdb:3WA9|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:74GQlSjGG1Ez6Uog74VXPLryKBc9606 rigid:urcB5q17tmLzlq6I1n6/60T8rEI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:O95785 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-1387294|uniprotkb:B7ZM82|uniprotkb:Q4G0E0|uniprotkb:Q6P6B0|uniprotkb:Q6ZN24|uniprotkb:Q7LDY6|uniprotkb:Q7LDZ1|uniprotkb:Q96IG5|uniprotkb:Q96SQ6|uniprotkb:Q9BUR8|uniprotkb:Q9NPT1|intact:EBI-10967552|uniprotkb:B3KVH1|uniprotkb:M0QY21 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:wiz_human(display_long)|uniprotkb:WIZ(gene name)|psi-mi:WIZ(display_short)|uniprotkb:ZNF803(gene name synonym)|uniprotkb:Widely-interspaced zinc finger-containing protein(gene name synonym)|uniprotkb:Zinc finger protein 803(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476790|imex:IM-26985-151 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N refseq:NP_067064.2|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001317324.1|interpro:IPR036236|mint:O95785|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010571"(positive regulation of nuclear cell cycle DNA replication)|go:"GO:0030496"(midbody)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990226"(histone methyltransferase binding) - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:FMQwuMDlEC/Zdsnayyl7kpQSmyg9606 rigid:urcB5q17tmLzlq6I1n6/60T8rEI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q9H9B1 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-766087|uniprotkb:Q8TCN7|uniprotkb:Q96F53|uniprotkb:Q96JF1|uniprotkb:Q96KH4|uniprotkb:B1AQ58|uniprotkb:B1AQ59|uniprotkb:Q86X08|ensembl:ENSP00000417980 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:ehmt1_human(display_long)|uniprotkb:KMT1D(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 5(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 1(gene name synonym)|uniprotkb:G9a-like protein 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1D(gene name synonym)|uniprotkb:EHMT1(gene name)|psi-mi:EHMT1(display_short)|uniprotkb:EUHMTASE1(gene name synonym)|uniprotkb:KIAA1876(gene name synonym)|uniprotkb:GLP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476790|imex:IM-26985-151 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N refseq:NP_001138999.1|refseq:NP_079033.4|ensembl:ENST00000371394|ensembl:ENSP00000485945|ensembl:ENSP00000417980|ensembl:ENST00000462484|ensembl:ENSP00000417328|dip:DIP-34585N|ensembl:ENSG00000181090(gene)|ensembl:ENST00000460843(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016604"(nuclear body)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038035|interpro:IPR043550|mint:Q9H9B1|rcsb pdb:2IGQ|rcsb pdb:2RFI|rcsb pdb:3B7B|rcsb pdb:3B95|rcsb pdb:3FPD|rcsb pdb:3HNA|rcsb pdb:3MO0|rcsb pdb:3MO2|rcsb pdb:3MO5|rcsb pdb:3SW9|rcsb pdb:3SWC|rcsb pdb:4I51|rcsb pdb:5TTG|rcsb pdb:5TUZ|rcsb pdb:5V9J|rcsb pdb:5VSD|rcsb pdb:5VSF|rcsb pdb:6BY9|rcsb pdb:6MBO|rcsb pdb:6MBP|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-6804760|reactome:R-HSA-8853884|reactome:R-HSA-8953750 - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:4L6QOGSsRPi8hDjS2/BYShjpnf89606 rigid:urcB5q17tmLzlq6I1n6/60T8rEI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q5TGY3 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-948813|ensembl:ENSP00000247087|ensembl:ENSP00000363123|ensembl:ENSP00000494394|ensembl:ENSP00000495072|ensembl:ENSP00000495665|ensembl:ENSP00000501218|uniprotkb:Q5TGY4|uniprotkb:Q6PJK1|uniprotkb:Q6ZUQ6|uniprotkb:Q99769|uniprotkb:Q9NUF5 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:ahdc1_human(display_long)|uniprotkb:AHDC1(gene name)|psi-mi:AHDC1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476790|imex:IM-26985-151 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N ensembl:ENSG00000126705(gene)|ensembl:ENST00000247087(transcript)|ensembl:ENST00000374011(transcript)|ensembl:ENST00000642245(transcript)|ensembl:ENST00000642416(transcript)|ensembl:ENST00000644989(transcript)|ensembl:ENST00000673934(transcript)|go:"GO:0003677"(DNA binding)|interpro:IPR032757|interpro:IPR039225|mint:Q5TGY3|refseq:NP_001025053.1|refseq:XP_011539557.1|refseq:XP_011539558.1|refseq:XP_011539559.1|refseq:XP_005245905.1|refseq:XP_005245906.1|refseq:XP_005245907.1|refseq:XP_005245908.1|refseq:XP_005245909.1 - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:lYUJEAEhxO204mZnqOd4Vf6K/g89606 rigid:urcB5q17tmLzlq6I1n6/60T8rEI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:O75461 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476790|imex:IM-26985-151 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198 - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rigid:urcB5q17tmLzlq6I1n6/60T8rEI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:P61244 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476790|imex:IM-26985-151 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750 - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:I5d1d/zT353OsLios95yEITNoWU9606 rigid:urcB5q17tmLzlq6I1n6/60T8rEI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q6IQ32 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-2838654|uniprotkb:A8K951|uniprotkb:Q9H9P3|uniprotkb:O94943|ensembl:ENSP00000262198 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:adnp2_human(display_long)|uniprotkb:ADNP2(gene name)|psi-mi:ADNP2(display_short)|uniprotkb:KIAA0863(gene name synonym)|uniprotkb:ZNF508(gene name synonym)|uniprotkb:Zinc finger protein 508(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476790|imex:IM-26985-151 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N refseq:NP_055728.1|refseq:XP_005266713.1|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0046872"(metal ion binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0071300"(cellular response to retinoic acid)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR038861|mint:Q6IQ32|ensembl:ENSG00000101544(gene)|ensembl:ENST00000262198(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus) - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:yzYCNBnFFszXO4X7vp01+DcaGvs9606 rigid:urcB5q17tmLzlq6I1n6/60T8rEI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q96KQ7 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-744366|uniprotkb:B0UZY2|uniprotkb:Q14349|uniprotkb:Q6PK06|uniprotkb:Q96MH5|uniprotkb:Q96QD0|uniprotkb:Q9UQL8|uniprotkb:Q9Y331|uniprotkb:Q5JQ92|uniprotkb:Q5JP83|uniprotkb:Q5JQA1|uniprotkb:Q5JQG3|ensembl:ENSP00000364687|ensembl:ENSP00000372864|ensembl:ENSP00000392305|ensembl:ENSP00000396119|ensembl:ENSP00000406110|ensembl:ENSP00000416957 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:ehmt2_human(display_long)|uniprotkb:KMT1C(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 3(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 8(gene name synonym)|uniprotkb:Protein G9a(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1C(gene name synonym)|uniprotkb:EHMT2(gene name)|psi-mi:EHMT2(display_short)|uniprotkb:BAT8(gene name synonym)|uniprotkb:G9A(gene name synonym)|uniprotkb:NG36(gene name synonym)|uniprotkb:C6orf30(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476790|imex:IM-26985-151 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N refseq:NP_006700.3|refseq:NP_079532.5|interpro:IPR043550|mint:Q96KQ7|rcsb pdb:2O8J|rcsb pdb:3DM1|rcsb pdb:3K5K|rcsb pdb:3RJW|rcsb pdb:4NVQ|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5TTF|rcsb pdb:5TUY|rcsb pdb:5V9I|rcsb pdb:5VSC|rcsb pdb:5VSE|rcsb pdb:6MM1|rcsb pdb:7BTV|rcsb pdb:7BUC|rcsb pdb:7DCF|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-6804760|reactome:R-HSA-73762|reactome:R-HSA-8853884|reactome:R-HSA-8953750|ensembl:ENSG00000204371(gene)|ensembl:ENSG00000206376(gene)|ensembl:ENSG00000227333(gene)|ensembl:ENSG00000232045(gene)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035265"(organ growth)|go:"GO:0035690"|go:"GO:0036166"(phenotypic switching)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045471"(response to ethanol)|ensembl:ENSG00000236759(gene)|ensembl:ENSG00000238134(gene)|ensembl:ENST00000375537(transcript)|ensembl:ENST00000383373(transcript)|ensembl:ENST00000420336(transcript)|ensembl:ENST00000421926(transcript)|ensembl:ENST00000429506(transcript)|ensembl:ENST00000450075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006306"(DNA methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007286"(spermatid development)|go:"GO:0007616"(long-term memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009566"(fertilization)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038034|refseq:NP_001305762.1|refseq:NP_001276342.1|dip:DIP-34461N - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:dblr0h0KBVa6kvaDHhnynRuHE6E9606 rigid:urcB5q17tmLzlq6I1n6/60T8rEI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q8N9R8 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-4395514|uniprotkb:Q3SXZ1|uniprotkb:Q3SXZ2|uniprotkb:Q5T163|uniprotkb:Q8N1I4|ensembl:ENSP00000336756 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:scai_human(display_long)|uniprotkb:SCAI(gene name)|psi-mi:SCAI(display_short)|uniprotkb:C9orf126(gene name synonym)|uniprotkb:Suppressor of cancer cell invasion protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476790|imex:IM-26985-151 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N refseq:NP_001138349.1|refseq:NP_775961.2|ensembl:ENSG00000173611(gene)|ensembl:ENST00000336505(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|interpro:IPR016607(Uncharacterised conserved protein UCP013022)|interpro:IPR022709|mint:Q8N9R8|reactome:R-HSA-5663220 - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:7rGLwUVUMTIQHugyN2BTnQwluiY9606 rigid:urcB5q17tmLzlq6I1n6/60T8rEI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q8IWI9 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-2815196|uniprotkb:E7ENI0|uniprotkb:F5H7K2|uniprotkb:Q9H9N7|uniprotkb:Q9H8R3|uniprotkb:Q9Y4E9|uniprotkb:Q9UG69|intact:EBI-11143500|intact:EBI-10969960|ensembl:ENSP00000219905|uniprotkb:B9EGR5 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:mgap_human(display_long)|uniprotkb:MGA(gene name)|psi-mi:MGA(display_short)|uniprotkb:KIAA0518(gene name synonym)|uniprotkb:MAD5(gene name synonym)|uniprotkb:MAX dimerization protein 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476790|imex:IM-26985-151 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N refseq:NP_001074010.2|ensembl:ENSP00000219905|ensembl:ENST00000566586|ensembl:ENSP00000456141|ensembl:ENSG00000174197(gene)|ensembl:ENST00000219905(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR018186|interpro:IPR032060|interpro:IPR036638|interpro:IPR036960|interpro:IPR037935|mint:Q8IWI9|reactome:R-HSA-8953750|refseq:NP_001157745.1|dip:DIP-57615N - - comment:"author score: 28" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:P4lo9EteCvikQQk5kyVkcobitLU9606 rigid:urcB5q17tmLzlq6I1n6/60T8rEI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:P62805 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476790|imex:IM-26985-151 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - comment:"author score: 31" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 rigid:urcB5q17tmLzlq6I1n6/60T8rEI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q9H582 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-2560435|uniprotkb:Q7LG67|uniprotkb:Q5TCC0|uniprotkb:Q6PI06|uniprotkb:Q9ULJ9|uniprotkb:A2RU71|uniprotkb:Q2TAM0|uniprotkb:Q6P446|uniprotkb:Q6BEP7|ensembl:ENSP00000337008|ensembl:ENSP00000359469 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:zn644_human(display_long)|uniprotkb:ZNF644(gene name)|psi-mi:ZNF644(display_short)|uniprotkb:KIAA1221(gene name synonym)|uniprotkb:ZEP2(gene name synonym)|uniprotkb:Zinc finger motif enhancer-binding protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476790|imex:IM-26985-151 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N refseq:NP_057704.2|refseq:NP_115562.3|refseq:NP_958357.1|refseq:XP_016857977.1|refseq:XP_016857978.1|refseq:XP_016857979.1|refseq:XP_016857980.1|refseq:XP_016857981.1|refseq:XP_016857982.1|refseq:XP_016857983.1|ensembl:ENSG00000122482(gene)|ensembl:ENST00000337393(transcript)|ensembl:ENST00000370440(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9H582 - - comment:"author score: 39" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:16MjfkV6aoDArzVV5Qi0K2HI2lg9606 rigid:urcB5q17tmLzlq6I1n6/60T8rEI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q5T3J3 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-473196|ensembl:ENSP00000358778|uniprotkb:Q86XS4|uniprotkb:Q8N3B6|uniprotkb:Q96HT4|uniprotkb:Q9NUM5|uniprotkb:Q9NV32 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:lrif1_human(display_long)|uniprotkb:Receptor-interacting factor 1(gene name synonym)|uniprotkb:LRIF1(gene name)|psi-mi:LRIF1(display_short)|uniprotkb:C1orf103(gene name synonym)|uniprotkb:RIF1(gene name synonym)|uniprotkb:HP1-binding protein enriched in inactive X chromosome protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476790|imex:IM-26985-151 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N ensembl:ENSG00000121931(gene)|ensembl:ENST00000369763(transcript)|go:"GO:0001740"(Barr body)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042974"(retinoic acid receptor binding)|interpro:IPR026191|mint:Q5T3J3|refseq:NP_001006946.1|refseq:NP_060842.3 - - comment:"author score: 40" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:0TZ2ePF1WLfBY9TO/jYZR4GiOKw9606 rigid:urcB5q17tmLzlq6I1n6/60T8rEI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q13112 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-1052944|uniprotkb:Q99548|ensembl:ENSP00000315700 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:caf1b_human(display_long)|uniprotkb:Chromatin assembly factor I p60 subunit(gene name synonym)|uniprotkb:M-phase phosphoprotein 7(gene name synonym)|uniprotkb:CHAF1B(gene name)|psi-mi:CHAF1B(display_short)|uniprotkb:CAF1A(gene name synonym)|uniprotkb:CAF1P60(gene name synonym)|uniprotkb:MPHOSPH7(gene name synonym)|uniprotkb:MPP7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476790|imex:IM-26985-151 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N refseq:NP_005432.1|dip:DIP-29243N|ensembl:ENSG00000159259(gene)|ensembl:ENST00000314103(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR029129|interpro:IPR036322|mint:Q13112|refseq:XP_016883966.1|refseq:XP_016883967.1 - - comment:"author score: 43" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:VVbW9mpUGYMRPxvlEk9FERHIsJs9606 rigid:urcB5q17tmLzlq6I1n6/60T8rEI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q9BYE7 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476790|imex:IM-26985-151 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N - - comment:"author score: 45" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 rigid:urcB5q17tmLzlq6I1n6/60T8rEI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q13111 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-1020839|uniprotkb:Q7Z7K3|uniprotkb:Q9UJY8|uniprotkb:Q6NXG5|intact:EBI-28985893|ensembl:ENSP00000301280 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:caf1a_human(display_long)|uniprotkb:CHAF1A(gene name)|psi-mi:CHAF1A(display_short)|uniprotkb:CAF(gene name synonym)|uniprotkb:CAF1P150(gene name synonym)|uniprotkb:Chromatin assembly factor I p150 subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476790|imex:IM-26985-151 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N refseq:NP_005474.2|ensembl:ENSG00000167670(gene)|ensembl:ENST00000301280(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070087"(chromo shadow domain binding)|interpro:IPR022043|interpro:IPR029091|interpro:IPR029105|mint:Q13111|ensembl:ENSP00000301280|dip:DIP-31135N - - comment:"author score: 46" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:8ZlQPVvmtN638aK8ZblErN5Bhjo9606 rigid:urcB5q17tmLzlq6I1n6/60T8rEI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q6P1K2 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-713832|uniprotkb:Q5TCJ8|uniprotkb:Q5TCJ9|uniprotkb:Q5TCK3|uniprotkb:Q69YZ9|uniprotkb:Q6PHR4|uniprotkb:Q86VJ6|uniprotkb:Q8N4T6|uniprotkb:Q9UBQ3|uniprotkb:A8K0C5|intact:EBI-2554676|uniprotkb:Q5TCK0|ensembl:ENSP00000357260|uniprotkb:Q5TCK1|uniprotkb:Q6ZVE6 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:pmf1_human(display_long)|uniprotkb:PMF1(gene name)|psi-mi:PMF1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476790|imex:IM-26985-151 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N ensembl:ENSG00000160783(gene)|ensembl:ENST00000368277(transcript)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0051301"(cell division)|interpro:IPR007128(Nnf1)|mint:Q6P1K2|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001186582.1|refseq:NP_001186583.1|refseq:NP_001186590.1|refseq:NP_001186592.1|refseq:NP_009152.2 - - comment:"author score: 61" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:76xPGmFgI3Pt1gsZMb3aD4hpPWM9606 rigid:urcB5q17tmLzlq6I1n6/60T8rEI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q14839 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-372916|uniprotkb:Q8IXZ5|intact:EBI-28978241|ensembl:ENSP00000440542 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:chd4_human(display_long)|uniprotkb:CHD4(gene name)|psi-mi:CHD4(display_short)|uniprotkb:ATP-dependent helicase CHD4(gene name synonym)|uniprotkb:Mi-2 autoantigen 218 kDa protein(gene name synonym)|uniprotkb:Mi2-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476790|imex:IM-26985-151 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N ensembl:ENSP00000440542|ensembl:ENST00000645095|ensembl:ENSP00000496634|refseq:NP_001264.2|refseq:XP_006719021.1|refseq:NP_001284482.1|ensembl:ENSG00000111642(gene)|ensembl:ENST00000544040(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070615"|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:Q14839|rcsb pdb:1MM2|rcsb pdb:1MM3|rcsb pdb:2EE1|rcsb pdb:2L5U|rcsb pdb:2L75|rcsb pdb:2N5N|rcsb pdb:4O9I|rcsb pdb:6BGG|rcsb pdb:6Q3M|rcsb pdb:6RYR|rcsb pdb:6RYU|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9031628|reactome:R-HSA-9679191|dip:DIP-31183N - - comment:"author score: 61" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:E9eHT/41SIFRiz54J81hvPQeHIE9606 rigid:urcB5q17tmLzlq6I1n6/60T8rEI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q96JM3 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-2560420|uniprotkb:Q8NC88|uniprotkb:B3KU06|uniprotkb:Q6P181|uniprotkb:Q9BST0|ensembl:ENSP00000354730|ensembl:ENSP00000496699 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:chap1_human(display_long)|uniprotkb:CHAMP(gene name synonym)|uniprotkb:CHAMP1(gene name)|psi-mi:CHAMP1(display_short)|uniprotkb:C13orf8(gene name synonym)|uniprotkb:CAMP(gene name synonym)|uniprotkb:KIAA1802(gene name synonym)|uniprotkb:ZNF828(gene name synonym)|uniprotkb:Zinc finger protein 828(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476790|imex:IM-26985-151 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N refseq:NP_001157616.1|refseq:NP_001157617.1|refseq:NP_115812.1|ensembl:ENSG00000198824(gene)|ensembl:ENST00000361283(transcript)|ensembl:ENST00000643483(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0016604"(nuclear body)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0046872"(metal ion binding)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0090543"(Flemming body)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR039330|mint:Q96JM3|rcsb pdb:6EKJ|rcsb pdb:6EKL|rcsb pdb:5XPT|rcsb pdb:5XPU - - comment:"author score: 64" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:Di1yMiufHKsy384vPjOgdncmQXw9606 rigid:urcB5q17tmLzlq6I1n6/60T8rEI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q96IY1 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-2554690|uniprotkb:Q9H2M5|uniprotkb:Q5SY75|uniprotkb:Q9Y415|uniprotkb:Q9NRN8|ensembl:ENSP00000355944|uniprotkb:E7ETD5 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:nsl1_human(display_long)|uniprotkb:C1orf48(gene name synonym)|uniprotkb:DC8(orf name)|uniprotkb:DC31(orf name)|uniprotkb:MIS14(orf name)|uniprotkb:NSL1(gene name)|psi-mi:NSL1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476790|imex:IM-26985-151 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N refseq:NP_056286.3|ensembl:ENSG00000117697(gene)|ensembl:ENST00000366977(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0005829"(cytosol)|go:"GO:0016607"(nuclear speck)|go:"GO:0051301"(cell division)|interpro:IPR013950(Kinetochore Mis14)|mint:Q96IY1|rcsb pdb:4NF9|rcsb pdb:5LSI|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-2500257|reactome:R-HSA-9648025|refseq:NP_001036014.1 - - comment:"author score: 65" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:w4K2MEHLfZvFECNhtDanXWF0LQk9606 rigid:urcB5q17tmLzlq6I1n6/60T8rEI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P83916 uniprotkb:Q9H2P0 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 intact:EBI-1764854|uniprotkb:E1P5Y2|uniprotkb:O94881|uniprotkb:Q5BKU2|uniprotkb:Q9UG34|intact:EBI-28975656|ensembl:ENSP00000342905|ensembl:ENSP00000360662|ensembl:ENSP00000379346|ensembl:ENSP00000379349|ensembl:ENSP00000483881 psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:adnp_human(display_long)|uniprotkb:ADNP(gene name)|psi-mi:ADNP(display_short)|uniprotkb:ADNP1(gene name synonym)|uniprotkb:KIAA0784(gene name synonym)|uniprotkb:Activity-dependent neuroprotective protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476790|imex:IM-26985-151 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N refseq:NP_001269460.1|refseq:NP_001269461.1|refseq:XP_011527049.1|refseq:NP_056154.1|refseq:NP_852107.1|ensembl:ENSP00000342905|ensembl:ENSP00000360662|ensembl:ENSP00000379346|ensembl:ENSP00000379349|ensembl:ENSP00000483881|ensembl:ENSG00000101126(gene)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0033484"(nitric oxide homeostasis)|ensembl:ENST00000349014(transcript)|ensembl:ENST00000371602(transcript)|ensembl:ENST00000396029(transcript)|ensembl:ENST00000396032(transcript)|ensembl:ENST00000621696(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007614"(short-term memory)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019934"(cGMP-mediated signaling)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042277"(peptide binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044849"(estrous cycle)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR038861|mint:Q9H2P0|refseq:XP_016883247.1|refseq:XP_016883248.1|refseq:NP_001334440.1|dip:DIP-47288N - - comment:"author score: 98" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rogid:QJTl6p2b0Lp7HnHP8sFd5Hv+WGk9606 rigid:urcB5q17tmLzlq6I1n6/60T8rEI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q5FBB7 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-989069|ensembl:ENSP00000263753|ensembl:ENSP00000414129|uniprotkb:Q5FBB4|uniprotkb:Q5FBB5|uniprotkb:Q5FBB6|uniprotkb:Q5FBB8|uniprotkb:Q8N579|uniprotkb:Q8WVL0|uniprotkb:Q9BVA8|uniprotkb:Q9H275|uniprotkb:Q588H5|intact:EBI-2555999 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:sgo1_human(display_long)|uniprotkb:SGO1(gene name)|psi-mi:SGO1(display_short)|uniprotkb:SGOL1(gene name synonym)|uniprotkb:Serologically defined breast cancer antigen NY-BR-85(gene name synonym)|uniprotkb:Shugoshin-like 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476901|imex:IM-26985-533 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N ensembl:ENSG00000129810(gene)|ensembl:ENST00000263753(transcript)|ensembl:ENST00000421451(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0019900"(kinase binding)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0071962"(mitotic sister chromatid cohesion, centromeric)|interpro:IPR011515(Shugoshin, C-terminal)|interpro:IPR011516(Shugoshin, N-terminal)|interpro:IPR028321|interpro:IPR038889|mint:Q5FBB7|rcsb pdb:3FGA|rcsb pdb:3Q6S|rcsb pdb:4A0I|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001012409.1|refseq:NP_001012410.1|refseq:NP_001012411.1|refseq:NP_001012412.1|refseq:NP_001012413.1|refseq:NP_001186180.1|refseq:NP_001186181.1|refseq:NP_001186182.1|refseq:NP_001186183.1|refseq:NP_001186184.1|refseq:NP_001186185.1|refseq:NP_001186186.1|refseq:NP_612493.1|refseq:XP_011531675.1|refseq:XP_011531677.1|refseq:XP_011531678.1|refseq:XP_011531679.1|dip:DIP-36614N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:rTa6IoM9PWfd6qOccSMZy1o0bBU9606 rigid:MyslTc0E+d49NlAsEFzzEATj1OE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q7Z3K3 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-1389308|uniprotkb:O75049|uniprotkb:Q5SZS2|uniprotkb:Q5SZS3|uniprotkb:Q5SZS4|uniprotkb:Q8TDZ7|uniprotkb:Q9Y4X7|uniprotkb:Q3LIC4|uniprotkb:Q5SZS1|intact:EBI-2560449|intact:EBI-11742841|uniprotkb:B4DTP8|uniprotkb:B4DYL9|uniprotkb:B7ZBY5|uniprotkb:E9PM80|intact:EBI-14072025|intact:EBI-17205119|intact:EBI-22321456|intact:EBI-12748249|intact:EBI-16429759|ensembl:ENSP00000271715 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:pogz_human(display_long)|uniprotkb:POGZ(gene name)|psi-mi:POGZ(display_short)|uniprotkb:KIAA0461(gene name synonym)|uniprotkb:Nbla00003(orf name)|uniprotkb:SUHW5(gene name synonym)|uniprotkb:ZNF280E(gene name synonym)|uniprotkb:ZNF635(gene name synonym)|uniprotkb:Suppressor of hairy wing homolog 5(gene name synonym)|uniprotkb:Zinc finger protein 280E(gene name synonym)|uniprotkb:Zinc finger protein 635(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476901|imex:IM-26985-533 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N refseq:NP_001181866.1|refseq:NP_001181867.1|refseq:NP_055915.2|refseq:NP_665739.3|refseq:NP_997054.1|refseq:XP_016856234.1|refseq:XP_016856235.1|refseq:XP_016856237.1|refseq:XP_016856238.1|refseq:XP_005245056.1|refseq:XP_005245057.1|refseq:XP_005245058.1|refseq:XP_005245062.1|refseq:XP_005245063.1|dip:DIP-38044N|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSG00000143442(gene)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|ensembl:ENST00000271715(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR004875(CENP-B protein)|interpro:IPR006600(Centromere protein B, helix-turn-helix)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q7Z3K3|rcsb pdb:2E72|rcsb pdb:2N3A|rcsb pdb:6EMP - - comment:"author score: 58" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:sCOIY8KsHRQtfcoSA9Tixl9yIsc9606 rigid:MyslTc0E+d49NlAsEFzzEATj1OE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q9H081 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-1001205|uniprotkb:Q96N24|ensembl:ENSP00000370557|ensembl:ENSP00000461252|ensembl:ENSP00000484532 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:mis12_human(display_long)|uniprotkb:MIS12(gene name)|psi-mi:MIS12(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476901|imex:IM-26985-533 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N refseq:NP_001245146.1|refseq:NP_001245147.1|refseq:NP_001245148.1|refseq:NP_001245149.1|refseq:XP_016880522.1|refseq:XP_016880523.1|refseq:XP_016880524.1|refseq:NP_076944.1|ensembl:ENSG00000167842(gene)|ensembl:ENST00000381165(transcript)|ensembl:ENST00000573759(transcript)|ensembl:ENST00000611091(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR008685(Mis12)|mint:Q9H081|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-5663220|refseq:XP_005256854.1 - - comment:"author score: 71" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:1qNMwDq3AYOWnRnPa2u3yt7O4109606 rigid:MyslTc0E+d49NlAsEFzzEATj1OE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q8N9Z2 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-8831284|uniprotkb:Q7Z756|ensembl:ENSP00000430897 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:cc71l_human(display_long)|uniprotkb:C7orf74(gene name synonym)|uniprotkb:CCDC71L(gene name)|psi-mi:CCDC71L(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476901|imex:IM-26985-533 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N refseq:NP_787080.2|ensembl:ENSG00000253276(gene)|ensembl:ENST00000523505(transcript)|go:"GO:0044255"(cellular lipid metabolic process)|go:"GO:0045600"(positive regulation of fat cell differentiation)|interpro:IPR026695|mint:Q8N9Z2 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:EZIjQPXDrGzdu/SyF9CrQGxgPuY9606 rigid:MyslTc0E+d49NlAsEFzzEATj1OE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:P62805 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476901|imex:IM-26985-533 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 rigid:MyslTc0E+d49NlAsEFzzEATj1OE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:P68431 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-79722|ensembl:ENSP00000352252|ensembl:ENSP00000358160|ensembl:ENSP00000366999|ensembl:ENSP00000480826|ensembl:ENSP00000482271|ensembl:ENSP00000483283|ensembl:ENSP00000484095|ensembl:ENSP00000484638|ensembl:ENSP00000484658|ensembl:ENSP00000484841|ensembl:ENSP00000489282|intact:EBI-1560041|uniprotkb:A0PJT7|uniprotkb:P02295|uniprotkb:P02296|uniprotkb:P16106|uniprotkb:Q6ISV8|uniprotkb:Q6NWP8|uniprotkb:Q6NWP9|uniprotkb:Q6NXU4|uniprotkb:Q71DJ3|uniprotkb:Q93081|uniprotkb:A5PLR1 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:h31_human(display_long)|uniprotkb:H3FA(gene name synonym)|uniprotkb:H3FL(gene name synonym)|uniprotkb:H3FD(gene name synonym)|uniprotkb:H3FI(gene name synonym)|uniprotkb:H3FH(gene name synonym)|uniprotkb:H3FK(gene name synonym)|uniprotkb:H3FF(gene name synonym)|uniprotkb:H3FJ(gene name synonym)|uniprotkb:H3FB(gene name synonym)|uniprotkb:Histone H3/a(gene name synonym)|uniprotkb:Histone H3/b(gene name synonym)|uniprotkb:Histone H3/c(gene name synonym)|uniprotkb:Histone H3/d(gene name synonym)|uniprotkb:Histone H3/f(gene name synonym)|uniprotkb:Histone H3/h(gene name synonym)|uniprotkb:Histone H3/i(gene name synonym)|uniprotkb:Histone H3/j(gene name synonym)|uniprotkb:Histone H3/k(gene name synonym)|uniprotkb:Histone H3/l(gene name synonym)|uniprotkb:H3C1(gene name)|psi-mi:H3C1(display_short)|uniprotkb:HIST1H3A(gene name synonym)|uniprotkb:H3C2(gene name)|psi-mi:H3C2(display_short)|uniprotkb:HIST1H3B(gene name synonym)|uniprotkb:H3C3(gene name)|psi-mi:H3C3(display_short)|uniprotkb:H3FC HIST1H3C(gene name synonym)|uniprotkb:H3C4(gene name)|psi-mi:H3C4(display_short)|uniprotkb:HIST1H3D(gene name synonym)|uniprotkb:H3C6(gene name)|psi-mi:H3C6(display_short)|uniprotkb:HIST1H3E(gene name synonym)|uniprotkb:H3C7(gene name)|psi-mi:H3C7(display_short)|uniprotkb:HIST1H3F(gene name synonym)|uniprotkb:H3C8(gene name)|psi-mi:H3C8(display_short)|uniprotkb:HIST1H3G(gene name synonym)|uniprotkb:H3C10(gene name)|psi-mi:H3C10(display_short)|uniprotkb:HIST1H3H(gene name synonym)|uniprotkb:H3C11(gene name)|psi-mi:H3C11(display_short)|uniprotkb:HIST1H3I(gene name synonym)|uniprotkb:H3C12(gene name)|psi-mi:H3C12(display_short)|uniprotkb:HIST1H3J(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476901|imex:IM-26985-533 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N rcsb pdb:4TN7|rcsb pdb:4U68|rcsb pdb:4UP0|rcsb pdb:4UY4|rcsb pdb:4X3K|rcsb pdb:4Y6L|rcsb pdb:4YHP|rcsb pdb:4YHZ|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z0R|rcsb pdb:4Z2M|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:4QBS|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B31|rcsb pdb:5C11|rcsb pdb:5C13|rcsb pdb:5C3I|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5D6Y|rcsb pdb:5DAH|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5FFV|rcsb pdb:5GH9|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5H6Q|rcsb pdb:5H6R|rcsb pdb:5HJB|rcsb pdb:5HJC|rcsb pdb:5HJD|rcsb pdb:5HYN|rcsb pdb:5IQL|rcsb pdb:5J3V|rcsb pdb:5J9S|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5B2J|rcsb pdb:5JRG|rcsb pdb:5KJH|rcsb pdb:5KJI|rcsb pdb:5KKL|rcsb pdb:5LUG|rcsb pdb:5M5G|rcsb pdb:5MR8|rcsb pdb:5NNC|rcsb pdb:5OY3|rcsb pdb:5SVX|rcsb pdb:5SVY|rcsb pdb:5SZB|rcsb pdb:5SZC|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5T1G|rcsb pdb:5T1I|rcsb pdb:5T8R|rcsb pdb:5TBN|rcsb pdb:5TDR|rcsb pdb:5TDW|rcsb pdb:5U2J|rcsb pdb:5V21|rcsb pdb:5V22|rcsb pdb:5VA6|rcsb pdb:5VAB|rcsb pdb:5VGE|rcsb pdb:5VNB|rcsb pdb:5NND|rcsb pdb:5WLE|rcsb pdb:5WVO|rcsb pdb:5WXG|rcsb pdb:5WXH|rcsb pdb:5WYI|rcsb pdb:5X60|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5XFQ|rcsb pdb:5XFR|rcsb pdb:5XNV|rcsb pdb:5XTZ|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Y20|rcsb pdb:5Y2F|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:6AXJ|rcsb pdb:6AZE|rcsb pdb:6BHD|rcsb pdb:6BHE|rcsb pdb:6BHG|rcsb pdb:6BHH|rcsb pdb:6BHI|rcsb pdb:6D07|rcsb pdb:6D08|rcsb pdb:6E83|rcsb pdb:6E86|rcsb pdb:5WFC|rcsb pdb:6F6D|rcsb pdb:6HTS|rcsb pdb:6IEU|rcsb pdb:6IIS|rcsb pdb:6IIT|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6JXD|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6LS6|rcsb pdb:6LSD|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MIL|rcsb pdb:6MIM|rcsb pdb:6MIN|rcsb pdb:6MIO|rcsb pdb:6MIQ|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6HKT|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2H|rcsb pdb:6V2K|rcsb pdb:6V3N|rcsb pdb:6V41|rcsb pdb:6V92|rcsb pdb:6VIL|rcsb pdb:6WAV|rcsb pdb:6WW4|rcsb pdb:6YIF|rcsb pdb:6YIH|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:6R92|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7KLR|rcsb pdb:7LYC|reactome:R-HSA-1266695|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|ensembl:ENSG00000197153(gene)|ensembl:ENSG00000197409(gene)|ensembl:ENSG00000273983(gene)|ensembl:ENSG00000274750(gene)|ensembl:ENSG00000275379(gene)|ensembl:ENSG00000275714(gene)|ensembl:ENSG00000277775(gene)|ensembl:ENSG00000278828(gene)|ensembl:ENSG00000286522(gene)|ensembl:ENSG00000287080(gene)|ensembl:ENST00000356476(transcript)|ensembl:ENST00000359303(transcript)|ensembl:ENST00000369163(transcript)|ensembl:ENST00000612966(transcript)|ensembl:ENST00000613854(transcript)|ensembl:ENST00000614378(transcript)|ensembl:ENST00000614911(transcript)|ensembl:ENST00000616365(transcript)|ensembl:ENST00000618052(transcript)|ensembl:ENST00000621411(transcript)|ensembl:ENST00000634733(transcript)|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-3247509|reactome:R-HSA-9710421|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060968"(obsolete regulation of gene silencing)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|interpro:IPR009072(Histone-fold)|mint:P68431|rcsb pdb:1CS9|rcsb pdb:1CT6|rcsb pdb:1O9S|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|rcsb pdb:1Q3L|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|rcsb pdb:2B2T|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|rcsb pdb:2B2U|rcsb pdb:2B2V|rcsb pdb:2B2W|rcsb pdb:2C1J|rcsb pdb:2C1N|go:"GO:0016020"(membrane)|rcsb pdb:2CO0|rcsb pdb:2CV5|rcsb pdb:2FSA|rcsb pdb:2KWJ|rcsb pdb:2KWK|rcsb pdb:2L75|rcsb pdb:2LBM|rcsb pdb:2LGG|rcsb pdb:2M0O|reactome:R-HSA-983231|reactome:R-HSA-977225|rcsb pdb:2NDG|rcsb pdb:2OQ6|rcsb pdb:2OT7|rcsb pdb:2OX0|rcsb pdb:2RI7|rcsb pdb:2RR4|rcsb pdb:2UXN|rcsb pdb:2V85|rcsb pdb:2V89|rcsb pdb:2VNF|rcsb pdb:2VPG|rcsb pdb:2X0L|rcsb pdb:3A1B|rcsb pdb:2NDF|rcsb pdb:3AFA|rcsb pdb:3AVR|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3B95|rcsb pdb:3FDT|rcsb pdb:3KMT|rcsb pdb:3KQI|rcsb pdb:3LQI|rcsb pdb:3LQJ|rcsb pdb:3MP1|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O37|rcsb pdb:3QJ6|rcsb pdb:3RIG|rcsb pdb:3RIY|rcsb pdb:3SOU|rcsb pdb:3SOW|rcsb pdb:3U31|rcsb pdb:3U3D|rcsb pdb:3U4S|rcsb pdb:3U5N|rcsb pdb:3U5O|rcsb pdb:3AZK|rcsb pdb:3U5P|rcsb pdb:3UEE|rcsb pdb:3UEF|rcsb pdb:3UII|rcsb pdb:3UIK|rcsb pdb:3V43|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:3ZG6|rcsb pdb:3ZVY|rcsb pdb:4A0J|rcsb pdb:4A0N|rcsb pdb:4A7J|rcsb pdb:3UIG|rcsb pdb:4BD3|rcsb pdb:4C1Q|rcsb pdb:4F4U|rcsb pdb:4F56|rcsb pdb:4FWF|rcsb pdb:4HON|rcsb pdb:4I51|rcsb pdb:4L7X|rcsb pdb:4LK9|rcsb pdb:4LKA|rcsb pdb:4LLB|rcsb pdb:4LXL|rcsb pdb:4N4H|rcsb pdb:4QBQ|rcsb pdb:4QBR|refseq:NP_003520.1|refseq:NP_003521.2|refseq:NP_003522.1|refseq:NP_003523.1|refseq:NP_003524.1|refseq:NP_003525.1|refseq:NP_003526.1|refseq:NP_003527.1|refseq:NP_003528.1|refseq:NP_066298.1|dip:DIP-29371N - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:ood0OohxZHuhsWZtO7U7GMc+LwM9606 rigid:MyslTc0E+d49NlAsEFzzEATj1OE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q9H582 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-2560435|uniprotkb:Q7LG67|uniprotkb:Q5TCC0|uniprotkb:Q6PI06|uniprotkb:Q9ULJ9|uniprotkb:A2RU71|uniprotkb:Q2TAM0|uniprotkb:Q6P446|uniprotkb:Q6BEP7|ensembl:ENSP00000337008|ensembl:ENSP00000359469 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:zn644_human(display_long)|uniprotkb:ZNF644(gene name)|psi-mi:ZNF644(display_short)|uniprotkb:KIAA1221(gene name synonym)|uniprotkb:ZEP2(gene name synonym)|uniprotkb:Zinc finger motif enhancer-binding protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476901|imex:IM-26985-533 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N refseq:NP_057704.2|refseq:NP_115562.3|refseq:NP_958357.1|refseq:XP_016857977.1|refseq:XP_016857978.1|refseq:XP_016857979.1|refseq:XP_016857980.1|refseq:XP_016857981.1|refseq:XP_016857982.1|refseq:XP_016857983.1|ensembl:ENSG00000122482(gene)|ensembl:ENST00000337393(transcript)|ensembl:ENST00000370440(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9H582 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:16MjfkV6aoDArzVV5Qi0K2HI2lg9606 rigid:MyslTc0E+d49NlAsEFzzEATj1OE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q86WX3 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-4479407|uniprotkb:B0QY96|uniprotkb:Q5JZA1|ensembl:ENSP00000333948 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:aros_human(display_long)|uniprotkb:RPS19BP1(gene name)|psi-mi:RPS19BP1(display_short)|uniprotkb:AROS(gene name synonym)|uniprotkb:40S ribosomal protein S19-binding protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476901|imex:IM-26985-533 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N refseq:NP_919307.1|ensembl:ENSG00000187051(gene)|ensembl:ENST00000334678(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0019899"(enzyme binding)|interpro:IPR023262|mint:Q86WX3|reactome:R-HSA-3371453 - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:A2pEtlH5IGyyVVhqX9EvlHE8XTM9606 rigid:MyslTc0E+d49NlAsEFzzEATj1OE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q5T3J3 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-473196|ensembl:ENSP00000358778|uniprotkb:Q86XS4|uniprotkb:Q8N3B6|uniprotkb:Q96HT4|uniprotkb:Q9NUM5|uniprotkb:Q9NV32 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:lrif1_human(display_long)|uniprotkb:Receptor-interacting factor 1(gene name synonym)|uniprotkb:LRIF1(gene name)|psi-mi:LRIF1(display_short)|uniprotkb:C1orf103(gene name synonym)|uniprotkb:RIF1(gene name synonym)|uniprotkb:HP1-binding protein enriched in inactive X chromosome protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476901|imex:IM-26985-533 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N ensembl:ENSG00000121931(gene)|ensembl:ENST00000369763(transcript)|go:"GO:0001740"(Barr body)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042974"(retinoic acid receptor binding)|interpro:IPR026191|mint:Q5T3J3|refseq:NP_001006946.1|refseq:NP_060842.3 - - comment:"author score: 31" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:0TZ2ePF1WLfBY9TO/jYZR4GiOKw9606 rigid:MyslTc0E+d49NlAsEFzzEATj1OE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:O75461 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476901|imex:IM-26985-533 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198 - - comment:"author score: 38" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rigid:MyslTc0E+d49NlAsEFzzEATj1OE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q13111 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-1020839|uniprotkb:Q7Z7K3|uniprotkb:Q9UJY8|uniprotkb:Q6NXG5|intact:EBI-28985893|ensembl:ENSP00000301280 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:caf1a_human(display_long)|uniprotkb:CHAF1A(gene name)|psi-mi:CHAF1A(display_short)|uniprotkb:CAF(gene name synonym)|uniprotkb:CAF1P150(gene name synonym)|uniprotkb:Chromatin assembly factor I p150 subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476901|imex:IM-26985-533 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N refseq:NP_005474.2|ensembl:ENSG00000167670(gene)|ensembl:ENST00000301280(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070087"(chromo shadow domain binding)|interpro:IPR022043|interpro:IPR029091|interpro:IPR029105|mint:Q13111|ensembl:ENSP00000301280|dip:DIP-31135N - - comment:"author score: 39" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:8ZlQPVvmtN638aK8ZblErN5Bhjo9606 rigid:MyslTc0E+d49NlAsEFzzEATj1OE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q14839 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-372916|uniprotkb:Q8IXZ5|intact:EBI-28978241|ensembl:ENSP00000440542 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:chd4_human(display_long)|uniprotkb:CHD4(gene name)|psi-mi:CHD4(display_short)|uniprotkb:ATP-dependent helicase CHD4(gene name synonym)|uniprotkb:Mi-2 autoantigen 218 kDa protein(gene name synonym)|uniprotkb:Mi2-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476901|imex:IM-26985-533 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N ensembl:ENSP00000440542|ensembl:ENST00000645095|ensembl:ENSP00000496634|refseq:NP_001264.2|refseq:XP_006719021.1|refseq:NP_001284482.1|ensembl:ENSG00000111642(gene)|ensembl:ENST00000544040(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070615"|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:Q14839|rcsb pdb:1MM2|rcsb pdb:1MM3|rcsb pdb:2EE1|rcsb pdb:2L5U|rcsb pdb:2L75|rcsb pdb:2N5N|rcsb pdb:4O9I|rcsb pdb:6BGG|rcsb pdb:6Q3M|rcsb pdb:6RYR|rcsb pdb:6RYU|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9031628|reactome:R-HSA-9679191|dip:DIP-31183N - - comment:"author score: 39" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:E9eHT/41SIFRiz54J81hvPQeHIE9606 rigid:MyslTc0E+d49NlAsEFzzEATj1OE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q13112 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-1052944|uniprotkb:Q99548|ensembl:ENSP00000315700 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:caf1b_human(display_long)|uniprotkb:Chromatin assembly factor I p60 subunit(gene name synonym)|uniprotkb:M-phase phosphoprotein 7(gene name synonym)|uniprotkb:CHAF1B(gene name)|psi-mi:CHAF1B(display_short)|uniprotkb:CAF1A(gene name synonym)|uniprotkb:CAF1P60(gene name synonym)|uniprotkb:MPHOSPH7(gene name synonym)|uniprotkb:MPP7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476901|imex:IM-26985-533 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N refseq:NP_005432.1|dip:DIP-29243N|ensembl:ENSG00000159259(gene)|ensembl:ENST00000314103(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR029129|interpro:IPR036322|mint:Q13112|refseq:XP_016883966.1|refseq:XP_016883967.1 - - comment:"author score: 42" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:VVbW9mpUGYMRPxvlEk9FERHIsJs9606 rigid:MyslTc0E+d49NlAsEFzzEATj1OE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:P61964 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476901|imex:IM-26985-533 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N - - comment:"author score: 43" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rigid:MyslTc0E+d49NlAsEFzzEATj1OE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q8IWI9 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-2815196|uniprotkb:E7ENI0|uniprotkb:F5H7K2|uniprotkb:Q9H9N7|uniprotkb:Q9H8R3|uniprotkb:Q9Y4E9|uniprotkb:Q9UG69|intact:EBI-11143500|intact:EBI-10969960|ensembl:ENSP00000219905|uniprotkb:B9EGR5 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:mgap_human(display_long)|uniprotkb:MGA(gene name)|psi-mi:MGA(display_short)|uniprotkb:KIAA0518(gene name synonym)|uniprotkb:MAD5(gene name synonym)|uniprotkb:MAX dimerization protein 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476901|imex:IM-26985-533 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N refseq:NP_001074010.2|ensembl:ENSP00000219905|ensembl:ENST00000566586|ensembl:ENSP00000456141|ensembl:ENSG00000174197(gene)|ensembl:ENST00000219905(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR018186|interpro:IPR032060|interpro:IPR036638|interpro:IPR036960|interpro:IPR037935|mint:Q8IWI9|reactome:R-HSA-8953750|refseq:NP_001157745.1|dip:DIP-57615N - - comment:"author score: 46" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:P4lo9EteCvikQQk5kyVkcobitLU9606 rigid:MyslTc0E+d49NlAsEFzzEATj1OE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q6P1K2 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-713832|uniprotkb:Q5TCJ8|uniprotkb:Q5TCJ9|uniprotkb:Q5TCK3|uniprotkb:Q69YZ9|uniprotkb:Q6PHR4|uniprotkb:Q86VJ6|uniprotkb:Q8N4T6|uniprotkb:Q9UBQ3|uniprotkb:A8K0C5|intact:EBI-2554676|uniprotkb:Q5TCK0|ensembl:ENSP00000357260|uniprotkb:Q5TCK1|uniprotkb:Q6ZVE6 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:pmf1_human(display_long)|uniprotkb:PMF1(gene name)|psi-mi:PMF1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476901|imex:IM-26985-533 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N ensembl:ENSG00000160783(gene)|ensembl:ENST00000368277(transcript)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0051301"(cell division)|interpro:IPR007128(Nnf1)|mint:Q6P1K2|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001186582.1|refseq:NP_001186583.1|refseq:NP_001186590.1|refseq:NP_001186592.1|refseq:NP_009152.2 - - comment:"author score: 54" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:76xPGmFgI3Pt1gsZMb3aD4hpPWM9606 rigid:MyslTc0E+d49NlAsEFzzEATj1OE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q96IY1 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-2554690|uniprotkb:Q9H2M5|uniprotkb:Q5SY75|uniprotkb:Q9Y415|uniprotkb:Q9NRN8|ensembl:ENSP00000355944|uniprotkb:E7ETD5 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:nsl1_human(display_long)|uniprotkb:C1orf48(gene name synonym)|uniprotkb:DC8(orf name)|uniprotkb:DC31(orf name)|uniprotkb:MIS14(orf name)|uniprotkb:NSL1(gene name)|psi-mi:NSL1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476901|imex:IM-26985-533 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N refseq:NP_056286.3|ensembl:ENSG00000117697(gene)|ensembl:ENST00000366977(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0005829"(cytosol)|go:"GO:0016607"(nuclear speck)|go:"GO:0051301"(cell division)|interpro:IPR013950(Kinetochore Mis14)|mint:Q96IY1|rcsb pdb:4NF9|rcsb pdb:5LSI|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-2500257|reactome:R-HSA-9648025|refseq:NP_001036014.1 - - comment:"author score: 64" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:w4K2MEHLfZvFECNhtDanXWF0LQk9606 rigid:MyslTc0E+d49NlAsEFzzEATj1OE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q9H2P0 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-1764854|uniprotkb:E1P5Y2|uniprotkb:O94881|uniprotkb:Q5BKU2|uniprotkb:Q9UG34|intact:EBI-28975656|ensembl:ENSP00000342905|ensembl:ENSP00000360662|ensembl:ENSP00000379346|ensembl:ENSP00000379349|ensembl:ENSP00000483881 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:adnp_human(display_long)|uniprotkb:ADNP(gene name)|psi-mi:ADNP(display_short)|uniprotkb:ADNP1(gene name synonym)|uniprotkb:KIAA0784(gene name synonym)|uniprotkb:Activity-dependent neuroprotective protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476901|imex:IM-26985-533 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N refseq:NP_001269460.1|refseq:NP_001269461.1|refseq:XP_011527049.1|refseq:NP_056154.1|refseq:NP_852107.1|ensembl:ENSP00000342905|ensembl:ENSP00000360662|ensembl:ENSP00000379346|ensembl:ENSP00000379349|ensembl:ENSP00000483881|ensembl:ENSG00000101126(gene)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0033484"(nitric oxide homeostasis)|ensembl:ENST00000349014(transcript)|ensembl:ENST00000371602(transcript)|ensembl:ENST00000396029(transcript)|ensembl:ENST00000396032(transcript)|ensembl:ENST00000621696(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007614"(short-term memory)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019934"(cGMP-mediated signaling)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042277"(peptide binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044849"(estrous cycle)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR038861|mint:Q9H2P0|refseq:XP_016883247.1|refseq:XP_016883248.1|refseq:NP_001334440.1|dip:DIP-47288N - - comment:"author score: 73" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:QJTl6p2b0Lp7HnHP8sFd5Hv+WGk9606 rigid:MyslTc0E+d49NlAsEFzzEATj1OE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q9BYE7 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476901|imex:IM-26985-533 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N - - comment:"author score: 73" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 rigid:MyslTc0E+d49NlAsEFzzEATj1OE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:Q969R5 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476901|imex:IM-26985-533 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750 - - comment:"author score: 80" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rigid:MyslTc0E+d49NlAsEFzzEATj1OE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13185 uniprotkb:P83916 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476901|imex:IM-26985-533 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N - - comment:"author score: 429" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rigid:MyslTc0E+d49NlAsEFzzEATj1OE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q5FBB7 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-989069|ensembl:ENSP00000263753|ensembl:ENSP00000414129|uniprotkb:Q5FBB4|uniprotkb:Q5FBB5|uniprotkb:Q5FBB6|uniprotkb:Q5FBB8|uniprotkb:Q8N579|uniprotkb:Q8WVL0|uniprotkb:Q9BVA8|uniprotkb:Q9H275|uniprotkb:Q588H5|intact:EBI-2555999 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:sgo1_human(display_long)|uniprotkb:SGO1(gene name)|psi-mi:SGO1(display_short)|uniprotkb:SGOL1(gene name synonym)|uniprotkb:Serologically defined breast cancer antigen NY-BR-85(gene name synonym)|uniprotkb:Shugoshin-like 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476970|imex:IM-26985-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N ensembl:ENSG00000129810(gene)|ensembl:ENST00000263753(transcript)|ensembl:ENST00000421451(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0010457"(centriole-centriole cohesion)|go:"GO:0019900"(kinase binding)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0071962"(mitotic sister chromatid cohesion, centromeric)|interpro:IPR011515(Shugoshin, C-terminal)|interpro:IPR011516(Shugoshin, N-terminal)|interpro:IPR028321|interpro:IPR038889|mint:Q5FBB7|rcsb pdb:3FGA|rcsb pdb:3Q6S|rcsb pdb:4A0I|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001012409.1|refseq:NP_001012410.1|refseq:NP_001012411.1|refseq:NP_001012412.1|refseq:NP_001012413.1|refseq:NP_001186180.1|refseq:NP_001186181.1|refseq:NP_001186182.1|refseq:NP_001186183.1|refseq:NP_001186184.1|refseq:NP_001186185.1|refseq:NP_001186186.1|refseq:NP_612493.1|refseq:XP_011531675.1|refseq:XP_011531677.1|refseq:XP_011531678.1|refseq:XP_011531679.1|dip:DIP-36614N - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:rTa6IoM9PWfd6qOccSMZy1o0bBU9606 rigid:a++5tZVO6PMeGkppF07qZCWtVv8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q7Z3K3 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-1389308|uniprotkb:O75049|uniprotkb:Q5SZS2|uniprotkb:Q5SZS3|uniprotkb:Q5SZS4|uniprotkb:Q8TDZ7|uniprotkb:Q9Y4X7|uniprotkb:Q3LIC4|uniprotkb:Q5SZS1|intact:EBI-2560449|intact:EBI-11742841|uniprotkb:B4DTP8|uniprotkb:B4DYL9|uniprotkb:B7ZBY5|uniprotkb:E9PM80|intact:EBI-14072025|intact:EBI-17205119|intact:EBI-22321456|intact:EBI-12748249|intact:EBI-16429759|ensembl:ENSP00000271715 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:pogz_human(display_long)|uniprotkb:POGZ(gene name)|psi-mi:POGZ(display_short)|uniprotkb:KIAA0461(gene name synonym)|uniprotkb:Nbla00003(orf name)|uniprotkb:SUHW5(gene name synonym)|uniprotkb:ZNF280E(gene name synonym)|uniprotkb:ZNF635(gene name synonym)|uniprotkb:Suppressor of hairy wing homolog 5(gene name synonym)|uniprotkb:Zinc finger protein 280E(gene name synonym)|uniprotkb:Zinc finger protein 635(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476970|imex:IM-26985-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N refseq:NP_001181866.1|refseq:NP_001181867.1|refseq:NP_055915.2|refseq:NP_665739.3|refseq:NP_997054.1|refseq:XP_016856234.1|refseq:XP_016856235.1|refseq:XP_016856237.1|refseq:XP_016856238.1|refseq:XP_005245056.1|refseq:XP_005245057.1|refseq:XP_005245058.1|refseq:XP_005245062.1|refseq:XP_005245063.1|dip:DIP-38044N|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSG00000143442(gene)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|ensembl:ENST00000271715(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR004875(CENP-B protein)|interpro:IPR006600(Centromere protein B, helix-turn-helix)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q7Z3K3|rcsb pdb:2E72|rcsb pdb:2N3A|rcsb pdb:6EMP - - comment:"author score: 47" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:sCOIY8KsHRQtfcoSA9Tixl9yIsc9606 rigid:a++5tZVO6PMeGkppF07qZCWtVv8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q9H081 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-1001205|uniprotkb:Q96N24|ensembl:ENSP00000370557|ensembl:ENSP00000461252|ensembl:ENSP00000484532 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:mis12_human(display_long)|uniprotkb:MIS12(gene name)|psi-mi:MIS12(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476970|imex:IM-26985-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N refseq:NP_001245146.1|refseq:NP_001245147.1|refseq:NP_001245148.1|refseq:NP_001245149.1|refseq:XP_016880522.1|refseq:XP_016880523.1|refseq:XP_016880524.1|refseq:NP_076944.1|ensembl:ENSG00000167842(gene)|ensembl:ENST00000381165(transcript)|ensembl:ENST00000573759(transcript)|ensembl:ENST00000611091(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR008685(Mis12)|mint:Q9H081|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-5663220|refseq:XP_005256854.1 - - comment:"author score: 96" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:1qNMwDq3AYOWnRnPa2u3yt7O4109606 rigid:a++5tZVO6PMeGkppF07qZCWtVv8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q09028 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476970|imex:IM-26985-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rigid:a++5tZVO6PMeGkppF07qZCWtVv8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q13263 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-78139|uniprotkb:O00677|ensembl:ENSP00000253024|uniprotkb:Q7Z632|uniprotkb:Q93040|uniprotkb:Q96IM1 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:tif1b_human(display_long)|uniprotkb:TRIM28(gene name)|psi-mi:TRIM28(display_short)|uniprotkb:KAP1(gene name synonym)|uniprotkb:RNF96(gene name synonym)|uniprotkb:TIF1B(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:Nuclear corepressor KAP-1(gene name synonym)|uniprotkb:KRAB-associated protein 1(gene name synonym)|uniprotkb:KRAB-interacting protein 1(gene name synonym)|uniprotkb:RING finger protein 96(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476970|imex:IM-26985-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N ensembl:ENSG00000130726(gene)|ensembl:ENST00000253024(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6QAJ|rcsb pdb:6QU1|reactome:R-HSA-212436|reactome:R-HSA-3899300|reactome:R-HSA-9609690|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q13263|rcsb pdb:1FP0|rcsb pdb:2RO1|rcsb pdb:2YVR|rcsb pdb:6H3A|rcsb pdb:6I9H|refseq:NP_005753.1|dip:DIP-30891N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:/yXCDGKUyyYnArOLyfzx6uPR9QY9606 rigid:a++5tZVO6PMeGkppF07qZCWtVv8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q71DI3 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-750650|uniprotkb:A2BDF6|uniprotkb:A6NFS4|uniprotkb:Q6B053|ensembl:ENSP00000333277|ensembl:ENSP00000358154|ensembl:ENSP00000385479 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:h32_human(display_long)|uniprotkb:H3C13(gene name)|psi-mi:H3C13(display_short)|uniprotkb:H3C14(gene name)|psi-mi:H3C14(display_short)|uniprotkb:H3C15(gene name)|psi-mi:H3C15(display_short)|uniprotkb:H3-clustered histone 13(gene name synonym)|uniprotkb:H3-clustered histone 14(gene name synonym)|uniprotkb:H3-clustered histone 15(gene name synonym)|uniprotkb:H3F2(gene name synonym)|uniprotkb:H3FM(gene name synonym)|uniprotkb:HIST2H3A(gene name synonym)|uniprotkb:HIST2H3C(gene name synonym)|uniprotkb:HIST2H3D(gene name synonym)|uniprotkb:Histone H3/m(gene name synonym)|uniprotkb:Histone H3/o(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476970|imex:IM-26985-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N refseq:NP_001005464.1|refseq:NP_001116847.1|refseq:NP_066403.2|dip:DIP-48606N|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|rcsb pdb:7BU9|rcsb pdb:7JO9|rcsb pdb:7JOA|reactome:R-HSA-3214858|reactome:R-HSA-3247509|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-983231|rcsb pdb:7JZV|reactome:R-HSA-1266695|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|ensembl:ENSG00000183598(gene)|ensembl:ENSG00000203811(gene)|ensembl:ENSG00000203852(gene)|ensembl:ENST00000331491(transcript)|ensembl:ENST00000369158(transcript)|ensembl:ENST00000403683(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:Q71DI3|rcsb pdb:2IIJ|rcsb pdb:2X4W|rcsb pdb:2X4X|rcsb pdb:2X4Y|rcsb pdb:3AV1|rcsb pdb:3DB3|rcsb pdb:3MO8|rcsb pdb:3QO2|rcsb pdb:3R93|rcsb pdb:4MZF|rcsb pdb:4MZG|rcsb pdb:4MZH|rcsb pdb:4OUC|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B40|rcsb pdb:5BO0|rcsb pdb:5CIU|rcsb pdb:5VAC|rcsb pdb:6ACE|rcsb pdb:6FML|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6Y5E|rcsb pdb:7BQZ - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:2TuVqWkeAnhHR4nrl0GNyUj1N3o9606 rigid:a++5tZVO6PMeGkppF07qZCWtVv8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:P59923 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-2849229|uniprotkb:Q3MJD1|ensembl:ENSP00000379387|ensembl:ENSP00000413073|ensembl:ENSP00000489139|ensembl:ENSP00000489368 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:zn445_human(display_long)|uniprotkb:ZNF445(gene name)|psi-mi:ZNF445(display_short)|uniprotkb:ZKSCAN15(gene name synonym)|uniprotkb:ZNF168(gene name synonym)|uniprotkb:Zinc finger protein 168(gene name synonym)|uniprotkb:Zinc finger protein with KRAB and SCAN domains 15(gene name synonym)|uniprotkb:ZFP445(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476970|imex:IM-26985-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N refseq:XP_011531976.1|refseq:NP_852466.1|refseq:XP_005265159.1|ensembl:ENSG00000185219(gene)|ensembl:ENSG00000283034(gene)|ensembl:ENST00000396077(transcript)|ensembl:ENST00000425708(transcript)|ensembl:ENST00000634579(transcript)|ensembl:ENST00000635479(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0071517"(maintenance of imprinting at mating-type locus)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|mint:P59923|reactome:R-HSA-212436 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:yTfAKMo3tO7walE9ol17nTIeuw89606 rigid:a++5tZVO6PMeGkppF07qZCWtVv8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:O95785 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-1387294|uniprotkb:B7ZM82|uniprotkb:Q4G0E0|uniprotkb:Q6P6B0|uniprotkb:Q6ZN24|uniprotkb:Q7LDY6|uniprotkb:Q7LDZ1|uniprotkb:Q96IG5|uniprotkb:Q96SQ6|uniprotkb:Q9BUR8|uniprotkb:Q9NPT1|intact:EBI-10967552|uniprotkb:B3KVH1|uniprotkb:M0QY21 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:wiz_human(display_long)|uniprotkb:WIZ(gene name)|psi-mi:WIZ(display_short)|uniprotkb:ZNF803(gene name synonym)|uniprotkb:Widely-interspaced zinc finger-containing protein(gene name synonym)|uniprotkb:Zinc finger protein 803(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476970|imex:IM-26985-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N refseq:NP_067064.2|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001317324.1|interpro:IPR036236|mint:O95785|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010571"(positive regulation of nuclear cell cycle DNA replication)|go:"GO:0030496"(midbody)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990226"(histone methyltransferase binding) - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:FMQwuMDlEC/Zdsnayyl7kpQSmyg9606 rigid:a++5tZVO6PMeGkppF07qZCWtVv8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:P62805 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476970|imex:IM-26985-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 rigid:a++5tZVO6PMeGkppF07qZCWtVv8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:P58557 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-2114647|uniprotkb:D3DSN2|uniprotkb:B7WPA9|uniprotkb:B7WPF7|ensembl:ENSP00000329614|ensembl:ENSP00000380805|ensembl:ENSP00000380813 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:ybey_human(display_long)|uniprotkb:YBEY(gene name)|psi-mi:YBEY(display_short)|uniprotkb:C21orf57(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476970|imex:IM-26985-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N refseq:NP_478061.1|refseq:NP_001300951.1|refseq:NP_001300952.1|refseq:NP_001300953.1|refseq:NP_001300954.1|refseq:NP_001300955.1|ensembl:ENSG00000182362(gene)|ensembl:ENST00000329319(transcript)|ensembl:ENST00000397691(transcript)|ensembl:ENST00000397701(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0006364"(rRNA processing)|go:"GO:0046872"(metal ion binding)|interpro:IPR002036(Protein of unknown function UPF0054)|interpro:IPR020549|interpro:IPR023091|mint:P58557 - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:VOjeUF0iThxy1T2ywZGHB8ILorc9606 rigid:a++5tZVO6PMeGkppF07qZCWtVv8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q9H9B1 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-766087|uniprotkb:Q8TCN7|uniprotkb:Q96F53|uniprotkb:Q96JF1|uniprotkb:Q96KH4|uniprotkb:B1AQ58|uniprotkb:B1AQ59|uniprotkb:Q86X08|ensembl:ENSP00000417980 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:ehmt1_human(display_long)|uniprotkb:KMT1D(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 5(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 1(gene name synonym)|uniprotkb:G9a-like protein 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1D(gene name synonym)|uniprotkb:EHMT1(gene name)|psi-mi:EHMT1(display_short)|uniprotkb:EUHMTASE1(gene name synonym)|uniprotkb:KIAA1876(gene name synonym)|uniprotkb:GLP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476970|imex:IM-26985-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N refseq:NP_001138999.1|refseq:NP_079033.4|ensembl:ENST00000371394|ensembl:ENSP00000485945|ensembl:ENSP00000417980|ensembl:ENST00000462484|ensembl:ENSP00000417328|dip:DIP-34585N|ensembl:ENSG00000181090(gene)|ensembl:ENST00000460843(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016604"(nuclear body)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038035|interpro:IPR043550|mint:Q9H9B1|rcsb pdb:2IGQ|rcsb pdb:2RFI|rcsb pdb:3B7B|rcsb pdb:3B95|rcsb pdb:3FPD|rcsb pdb:3HNA|rcsb pdb:3MO0|rcsb pdb:3MO2|rcsb pdb:3MO5|rcsb pdb:3SW9|rcsb pdb:3SWC|rcsb pdb:4I51|rcsb pdb:5TTG|rcsb pdb:5TUZ|rcsb pdb:5V9J|rcsb pdb:5VSD|rcsb pdb:5VSF|rcsb pdb:6BY9|rcsb pdb:6MBO|rcsb pdb:6MBP|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-6804760|reactome:R-HSA-8853884|reactome:R-HSA-8953750 - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:4L6QOGSsRPi8hDjS2/BYShjpnf89606 rigid:a++5tZVO6PMeGkppF07qZCWtVv8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q96KQ7 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-744366|uniprotkb:B0UZY2|uniprotkb:Q14349|uniprotkb:Q6PK06|uniprotkb:Q96MH5|uniprotkb:Q96QD0|uniprotkb:Q9UQL8|uniprotkb:Q9Y331|uniprotkb:Q5JQ92|uniprotkb:Q5JP83|uniprotkb:Q5JQA1|uniprotkb:Q5JQG3|ensembl:ENSP00000364687|ensembl:ENSP00000372864|ensembl:ENSP00000392305|ensembl:ENSP00000396119|ensembl:ENSP00000406110|ensembl:ENSP00000416957 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:ehmt2_human(display_long)|uniprotkb:KMT1C(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 3(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 8(gene name synonym)|uniprotkb:Protein G9a(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1C(gene name synonym)|uniprotkb:EHMT2(gene name)|psi-mi:EHMT2(display_short)|uniprotkb:BAT8(gene name synonym)|uniprotkb:G9A(gene name synonym)|uniprotkb:NG36(gene name synonym)|uniprotkb:C6orf30(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476970|imex:IM-26985-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N refseq:NP_006700.3|refseq:NP_079532.5|interpro:IPR043550|mint:Q96KQ7|rcsb pdb:2O8J|rcsb pdb:3DM1|rcsb pdb:3K5K|rcsb pdb:3RJW|rcsb pdb:4NVQ|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5TTF|rcsb pdb:5TUY|rcsb pdb:5V9I|rcsb pdb:5VSC|rcsb pdb:5VSE|rcsb pdb:6MM1|rcsb pdb:7BTV|rcsb pdb:7BUC|rcsb pdb:7DCF|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-6804760|reactome:R-HSA-73762|reactome:R-HSA-8853884|reactome:R-HSA-8953750|ensembl:ENSG00000204371(gene)|ensembl:ENSG00000206376(gene)|ensembl:ENSG00000227333(gene)|ensembl:ENSG00000232045(gene)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035265"(organ growth)|go:"GO:0035690"|go:"GO:0036166"(phenotypic switching)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045471"(response to ethanol)|ensembl:ENSG00000236759(gene)|ensembl:ENSG00000238134(gene)|ensembl:ENST00000375537(transcript)|ensembl:ENST00000383373(transcript)|ensembl:ENST00000420336(transcript)|ensembl:ENST00000421926(transcript)|ensembl:ENST00000429506(transcript)|ensembl:ENST00000450075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006306"(DNA methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007286"(spermatid development)|go:"GO:0007616"(long-term memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009566"(fertilization)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038034|refseq:NP_001305762.1|refseq:NP_001276342.1|dip:DIP-34461N - - comment:"author score: 28" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:dblr0h0KBVa6kvaDHhnynRuHE6E9606 rigid:a++5tZVO6PMeGkppF07qZCWtVv8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q9H582 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-2560435|uniprotkb:Q7LG67|uniprotkb:Q5TCC0|uniprotkb:Q6PI06|uniprotkb:Q9ULJ9|uniprotkb:A2RU71|uniprotkb:Q2TAM0|uniprotkb:Q6P446|uniprotkb:Q6BEP7|ensembl:ENSP00000337008|ensembl:ENSP00000359469 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:zn644_human(display_long)|uniprotkb:ZNF644(gene name)|psi-mi:ZNF644(display_short)|uniprotkb:KIAA1221(gene name synonym)|uniprotkb:ZEP2(gene name synonym)|uniprotkb:Zinc finger motif enhancer-binding protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476970|imex:IM-26985-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N refseq:NP_057704.2|refseq:NP_115562.3|refseq:NP_958357.1|refseq:XP_016857977.1|refseq:XP_016857978.1|refseq:XP_016857979.1|refseq:XP_016857980.1|refseq:XP_016857981.1|refseq:XP_016857982.1|refseq:XP_016857983.1|ensembl:ENSG00000122482(gene)|ensembl:ENST00000337393(transcript)|ensembl:ENST00000370440(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9H582 - - comment:"author score: 31" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:16MjfkV6aoDArzVV5Qi0K2HI2lg9606 rigid:a++5tZVO6PMeGkppF07qZCWtVv8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q96JM3 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-2560420|uniprotkb:Q8NC88|uniprotkb:B3KU06|uniprotkb:Q6P181|uniprotkb:Q9BST0|ensembl:ENSP00000354730|ensembl:ENSP00000496699 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:chap1_human(display_long)|uniprotkb:CHAMP(gene name synonym)|uniprotkb:CHAMP1(gene name)|psi-mi:CHAMP1(display_short)|uniprotkb:C13orf8(gene name synonym)|uniprotkb:CAMP(gene name synonym)|uniprotkb:KIAA1802(gene name synonym)|uniprotkb:ZNF828(gene name synonym)|uniprotkb:Zinc finger protein 828(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476970|imex:IM-26985-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N refseq:NP_001157616.1|refseq:NP_001157617.1|refseq:NP_115812.1|ensembl:ENSG00000198824(gene)|ensembl:ENST00000361283(transcript)|ensembl:ENST00000643483(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0016604"(nuclear body)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0046872"(metal ion binding)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0090543"(Flemming body)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR039330|mint:Q96JM3|rcsb pdb:6EKJ|rcsb pdb:6EKL|rcsb pdb:5XPT|rcsb pdb:5XPU - - comment:"author score: 45" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:Di1yMiufHKsy384vPjOgdncmQXw9606 rigid:a++5tZVO6PMeGkppF07qZCWtVv8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q13111 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-1020839|uniprotkb:Q7Z7K3|uniprotkb:Q9UJY8|uniprotkb:Q6NXG5|intact:EBI-28985893|ensembl:ENSP00000301280 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:caf1a_human(display_long)|uniprotkb:CHAF1A(gene name)|psi-mi:CHAF1A(display_short)|uniprotkb:CAF(gene name synonym)|uniprotkb:CAF1P150(gene name synonym)|uniprotkb:Chromatin assembly factor I p150 subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476970|imex:IM-26985-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N refseq:NP_005474.2|ensembl:ENSG00000167670(gene)|ensembl:ENST00000301280(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070087"(chromo shadow domain binding)|interpro:IPR022043|interpro:IPR029091|interpro:IPR029105|mint:Q13111|ensembl:ENSP00000301280|dip:DIP-31135N - - comment:"author score: 61" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:8ZlQPVvmtN638aK8ZblErN5Bhjo9606 rigid:a++5tZVO6PMeGkppF07qZCWtVv8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q6P1K2 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-713832|uniprotkb:Q5TCJ8|uniprotkb:Q5TCJ9|uniprotkb:Q5TCK3|uniprotkb:Q69YZ9|uniprotkb:Q6PHR4|uniprotkb:Q86VJ6|uniprotkb:Q8N4T6|uniprotkb:Q9UBQ3|uniprotkb:A8K0C5|intact:EBI-2554676|uniprotkb:Q5TCK0|ensembl:ENSP00000357260|uniprotkb:Q5TCK1|uniprotkb:Q6ZVE6 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:pmf1_human(display_long)|uniprotkb:PMF1(gene name)|psi-mi:PMF1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476970|imex:IM-26985-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N ensembl:ENSG00000160783(gene)|ensembl:ENST00000368277(transcript)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0051301"(cell division)|interpro:IPR007128(Nnf1)|mint:Q6P1K2|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001186582.1|refseq:NP_001186583.1|refseq:NP_001186590.1|refseq:NP_001186592.1|refseq:NP_009152.2 - - comment:"author score: 67" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:76xPGmFgI3Pt1gsZMb3aD4hpPWM9606 rigid:a++5tZVO6PMeGkppF07qZCWtVv8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q13112 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-1052944|uniprotkb:Q99548|ensembl:ENSP00000315700 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:caf1b_human(display_long)|uniprotkb:Chromatin assembly factor I p60 subunit(gene name synonym)|uniprotkb:M-phase phosphoprotein 7(gene name synonym)|uniprotkb:CHAF1B(gene name)|psi-mi:CHAF1B(display_short)|uniprotkb:CAF1A(gene name synonym)|uniprotkb:CAF1P60(gene name synonym)|uniprotkb:MPHOSPH7(gene name synonym)|uniprotkb:MPP7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476970|imex:IM-26985-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N refseq:NP_005432.1|dip:DIP-29243N|ensembl:ENSG00000159259(gene)|ensembl:ENST00000314103(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR029129|interpro:IPR036322|mint:Q13112|refseq:XP_016883966.1|refseq:XP_016883967.1 - - comment:"author score: 67" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:VVbW9mpUGYMRPxvlEk9FERHIsJs9606 rigid:a++5tZVO6PMeGkppF07qZCWtVv8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q96IY1 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-2554690|uniprotkb:Q9H2M5|uniprotkb:Q5SY75|uniprotkb:Q9Y415|uniprotkb:Q9NRN8|ensembl:ENSP00000355944|uniprotkb:E7ETD5 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:nsl1_human(display_long)|uniprotkb:C1orf48(gene name synonym)|uniprotkb:DC8(orf name)|uniprotkb:DC31(orf name)|uniprotkb:MIS14(orf name)|uniprotkb:NSL1(gene name)|psi-mi:NSL1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476970|imex:IM-26985-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N refseq:NP_056286.3|ensembl:ENSG00000117697(gene)|ensembl:ENST00000366977(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0005829"(cytosol)|go:"GO:0016607"(nuclear speck)|go:"GO:0051301"(cell division)|interpro:IPR013950(Kinetochore Mis14)|mint:Q96IY1|rcsb pdb:4NF9|rcsb pdb:5LSI|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-2500257|reactome:R-HSA-9648025|refseq:NP_001036014.1 - - comment:"author score: 85" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:w4K2MEHLfZvFECNhtDanXWF0LQk9606 rigid:a++5tZVO6PMeGkppF07qZCWtVv8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:P83916 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476970|imex:IM-26985-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N - - comment:"author score: 115" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rigid:a++5tZVO6PMeGkppF07qZCWtVv8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P45973 uniprotkb:Q13185 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25476970|imex:IM-26985-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N - - comment:"author score: 223" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rigid:a++5tZVO6PMeGkppF07qZCWtVv8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95931 uniprotkb:P81605 intact:EBI-3923843|uniprotkb:Q86T17|ensembl:ENSP00000216133 intact:EBI-395625|uniprotkb:P58461|uniprotkb:A5JHP2|uniprotkb:A5JHP3|uniprotkb:Q53YJ2|ensembl:ENSP00000293371 psi-mi:cbx7_human(display_long)|uniprotkb:CBX7(gene name)|psi-mi:CBX7(display_short) psi-mi:dcd_human(display_long)|uniprotkb:AIDD(gene name synonym)|uniprotkb:DSEP(gene name synonym)|uniprotkb:Preproteolysin(gene name synonym)|uniprotkb:DCD(gene name)|psi-mi:DCD(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477072|imex:IM-26985-387 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783640.1|ensembl:ENSG00000100307(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|mint:O95931|rcsb pdb:2K1B|rcsb pdb:2L12|rcsb pdb:2L1B|rcsb pdb:3GS2|rcsb pdb:4MN3|rcsb pdb:5EPJ|rcsb pdb:6V2R|ensembl:ENST00000216133(transcript)|dip:DIP-44565N refseq:NP_444513.1|refseq:NP_001287783.1|ensembl:ENSG00000161634(gene)|ensembl:ENST00000293371(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008233"(peptidase activity)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR028130|interpro:IPR043557|mint:P81605|rcsb pdb:2KSG|rcsb pdb:2NDK|rcsb pdb:2YMK|rcsb pdb:6SHK|reactome:R-HSA-6803157 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:LDXV9srMj1BL2CaSSot1Bn0/EW49606 rogid:M8PkKVWx98nhtd79ods05mqw8Ls9606 rigid:PeLDjUQttTVEtpJCTmgCrrC39VQ false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95931 uniprotkb:Q8NDX5 intact:EBI-3923843|uniprotkb:Q86T17|ensembl:ENSP00000216133 intact:EBI-1223801|uniprotkb:Q5HYF0|uniprotkb:Q6NSG2|uniprotkb:Q8NFT7|uniprotkb:Q8NFZ1|uniprotkb:Q8TBM2|uniprotkb:Q9H971|uniprotkb:Q9H9I4|uniprotkb:A2RRP9|ensembl:ENSP00000420271 psi-mi:cbx7_human(display_long)|uniprotkb:CBX7(gene name)|psi-mi:CBX7(display_short) psi-mi:phc3_human(display_long)|uniprotkb:PHC3(gene name)|psi-mi:PHC3(display_short)|uniprotkb:EDR3(gene name synonym)|uniprotkb:PH3(gene name synonym)|uniprotkb:Homolog of polyhomeotic 3(gene name synonym)|uniprotkb:Early development regulatory protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477072|imex:IM-26985-387 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783640.1|ensembl:ENSG00000100307(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|mint:O95931|rcsb pdb:2K1B|rcsb pdb:2L12|rcsb pdb:2L1B|rcsb pdb:3GS2|rcsb pdb:4MN3|rcsb pdb:5EPJ|rcsb pdb:6V2R|ensembl:ENST00000216133(transcript)|dip:DIP-44565N refseq:NP_079223.3|refseq:NP_001295045.1|ensembl:ENSP00000420271|ensembl:ENST00000495893|ensembl:ENSP00000420294|ensembl:ENST00000497658|ensembl:ENSP00000420454|ensembl:ENSG00000173889(gene)|ensembl:ENST00000494943(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:Q8NDX5|rcsb pdb:4PZN|rcsb pdb:4PZO|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:LDXV9srMj1BL2CaSSot1Bn0/EW49606 rogid:hB1EMs+lCv19uuJ1O7+QiVCUoo89606 rigid:PeLDjUQttTVEtpJCTmgCrrC39VQ false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95931 uniprotkb:P78364 intact:EBI-3923843|uniprotkb:Q86T17|ensembl:ENSP00000216133 intact:EBI-725403|uniprotkb:Q8WVM3|uniprotkb:Q9BU63|uniprotkb:D3DUV4|ensembl:ENSP00000437659|ensembl:ENSP00000440674 psi-mi:cbx7_human(display_long)|uniprotkb:CBX7(gene name)|psi-mi:CBX7(display_short) psi-mi:phc1_human(display_long)|uniprotkb:Early development regulatory protein 1(gene name synonym)|uniprotkb:PHC1(gene name)|psi-mi:PHC1(display_short)|uniprotkb:EDR1(gene name synonym)|uniprotkb:PH1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477072|imex:IM-26985-387 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783640.1|ensembl:ENSG00000100307(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|mint:O95931|rcsb pdb:2K1B|rcsb pdb:2L12|rcsb pdb:2L1B|rcsb pdb:3GS2|rcsb pdb:4MN3|rcsb pdb:5EPJ|rcsb pdb:6V2R|ensembl:ENST00000216133(transcript)|dip:DIP-44565N refseq:NP_004417.2|ensembl:ENSG00000111752(gene)|ensembl:ENST00000543824(transcript)|ensembl:ENST00000544916(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:P78364|rcsb pdb:2L8E|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|dip:DIP-44567N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:LDXV9srMj1BL2CaSSot1Bn0/EW49606 rogid:0dDjrgvWcP5Sx8h+qUj7awuM3ko9606 rigid:PeLDjUQttTVEtpJCTmgCrrC39VQ false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95931 uniprotkb:Q8IXK0 intact:EBI-3923843|uniprotkb:Q86T17|ensembl:ENSP00000216133 intact:EBI-713786|uniprotkb:Q8N306|uniprotkb:Q8TAG8|uniprotkb:A1L4Q1|uniprotkb:Q2TAL3|uniprotkb:Q5T0C1|uniprotkb:Q6NUJ6|uniprotkb:Q6ZQR1|uniprotkb:Q96BL4|uniprotkb:Q9Y4Y7|ensembl:ENSP00000257118|uniprotkb:D3DPR2|uniprotkb:A8KA40 psi-mi:cbx7_human(display_long)|uniprotkb:CBX7(gene name)|psi-mi:CBX7(display_short) psi-mi:phc2_human(display_long)|uniprotkb:Early development regulatory protein 2(gene name synonym)|uniprotkb:PHC2(gene name)|psi-mi:PHC2(display_short)|uniprotkb:EDR2(gene name synonym)|uniprotkb:PH2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477072|imex:IM-26985-387 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783640.1|ensembl:ENSG00000100307(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|mint:O95931|rcsb pdb:2K1B|rcsb pdb:2L12|rcsb pdb:2L1B|rcsb pdb:3GS2|rcsb pdb:4MN3|rcsb pdb:5EPJ|rcsb pdb:6V2R|ensembl:ENST00000216133(transcript)|dip:DIP-44565N interpro:IPR038603|mint:Q8IXK0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR013761(Sterile alpha motif-type)|ensembl:ENSG00000134686(gene)|ensembl:ENST00000257118(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|refseq:NP_004418.2|refseq:NP_932157.1|refseq:XP_016856005.1|refseq:XP_016856006.1|refseq:XP_016856007.1|refseq:XP_005270627.1|dip:DIP-34464N - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:LDXV9srMj1BL2CaSSot1Bn0/EW49606 rogid:7si/KU2tHoxviuCr70ncQERDWmY9606 rigid:PeLDjUQttTVEtpJCTmgCrrC39VQ false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95931 uniprotkb:P35226 intact:EBI-3923843|uniprotkb:Q86T17|ensembl:ENSP00000216133 intact:EBI-2341576|uniprotkb:Q5T8Z3|uniprotkb:Q96F37|uniprotkb:Q16030|intact:EBI-28989037|ensembl:ENSP00000365851 psi-mi:cbx7_human(display_long)|uniprotkb:CBX7(gene name)|psi-mi:CBX7(display_short) psi-mi:bmi1_human(display_long)|uniprotkb:BMI1(gene name)|psi-mi:BMI1(display_short)|uniprotkb:PCGF4(gene name synonym)|uniprotkb:RNF51(gene name synonym)|uniprotkb:Polycomb group RING finger protein 4(gene name synonym)|uniprotkb:RING finger protein 51(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477072|imex:IM-26985-387 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783640.1|ensembl:ENSG00000100307(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|mint:O95931|rcsb pdb:2K1B|rcsb pdb:2L12|rcsb pdb:2L1B|rcsb pdb:3GS2|rcsb pdb:4MN3|rcsb pdb:5EPJ|rcsb pdb:6V2R|ensembl:ENST00000216133(transcript)|dip:DIP-44565N refseq:NP_001190991.1|refseq:NP_005171.4|ensembl:ENSP00000365851|dip:DIP-41879N|ensembl:ENSG00000168283(gene)|ensembl:ENST00000376663(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006959"(humoral immune response)|go:"GO:0007379"(segment specification)|go:"GO:0007420"(brain development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35226|rcsb pdb:2H0D|rcsb pdb:2NA1|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:5FR6|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:LDXV9srMj1BL2CaSSot1Bn0/EW49606 rogid:ruyez2gHfd/si8gxYUDZzZ1L4689606 rigid:PeLDjUQttTVEtpJCTmgCrrC39VQ false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95931 uniprotkb:P84085 intact:EBI-3923843|uniprotkb:Q86T17|ensembl:ENSP00000216133 intact:EBI-4289908|uniprotkb:P26437|ensembl:ENSP00000000233 psi-mi:cbx7_human(display_long)|uniprotkb:CBX7(gene name)|psi-mi:CBX7(display_short) psi-mi:arf5_human(display_long)|uniprotkb:ARF5(gene name)|psi-mi:ARF5(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477072|imex:IM-26985-387 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783640.1|ensembl:ENSG00000100307(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|mint:O95931|rcsb pdb:2K1B|rcsb pdb:2L12|rcsb pdb:2L1B|rcsb pdb:3GS2|rcsb pdb:4MN3|rcsb pdb:5EPJ|rcsb pdb:6V2R|ensembl:ENST00000216133(transcript)|dip:DIP-44565N ensembl:ENSG00000004059(gene)|ensembl:ENST00000000233(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P84085|rcsb pdb:2B6H|reactome:R-HSA-6807878|reactome:R-HSA-6811434|refseq:NP_001653.1|dip:DIP-61289N - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:LDXV9srMj1BL2CaSSot1Bn0/EW49606 rogid:da8exbGR3MGxZ6CPZqLvqJbyUYI9606 rigid:PeLDjUQttTVEtpJCTmgCrrC39VQ false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95931 uniprotkb:Q99496 intact:EBI-3923843|uniprotkb:Q86T17|ensembl:ENSP00000216133 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:cbx7_human(display_long)|uniprotkb:CBX7(gene name)|psi-mi:CBX7(display_short) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477072|imex:IM-26985-387 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783640.1|ensembl:ENSG00000100307(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|mint:O95931|rcsb pdb:2K1B|rcsb pdb:2L12|rcsb pdb:2L1B|rcsb pdb:3GS2|rcsb pdb:4MN3|rcsb pdb:5EPJ|rcsb pdb:6V2R|ensembl:ENST00000216133(transcript)|dip:DIP-44565N refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 - - comment:"author score: 29" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:LDXV9srMj1BL2CaSSot1Bn0/EW49606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rigid:PeLDjUQttTVEtpJCTmgCrrC39VQ false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95931 uniprotkb:Q9Y2K6 intact:EBI-3923843|uniprotkb:Q86T17|ensembl:ENSP00000216133 intact:EBI-2511991|ensembl:ENSP00000313811|ensembl:ENSP00000351122|ensembl:ENSP00000361506|intact:EBI-28979612|uniprotkb:Q9UQN8|uniprotkb:Q8IXQ1|uniprotkb:Q9UQP0|uniprotkb:Q96LG5|uniprotkb:Q541F1 psi-mi:cbx7_human(display_long)|uniprotkb:CBX7(gene name)|psi-mi:CBX7(display_short) psi-mi:ubp20_human(display_long)|uniprotkb:USP20(gene name)|psi-mi:USP20(display_short)|uniprotkb:KIAA1003(gene name synonym)|uniprotkb:LSFR3A(gene name synonym)|uniprotkb:VDU2(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 20(gene name synonym)|uniprotkb:Deubiquitinating enzyme 20(gene name synonym)|uniprotkb:VHL-interacting deubiquitinating enzyme 2(gene name synonym)|uniprotkb:Ubiquitin thioesterase 20(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477072|imex:IM-26985-387 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_783640.1|ensembl:ENSG00000100307(gene)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043000|mint:O95931|rcsb pdb:2K1B|rcsb pdb:2L12|rcsb pdb:2L1B|rcsb pdb:3GS2|rcsb pdb:4MN3|rcsb pdb:5EPJ|rcsb pdb:6V2R|ensembl:ENST00000216133(transcript)|dip:DIP-44565N ensembl:ENST00000315480(transcript)|ensembl:ENST00000358355(transcript)|ensembl:ENST00000372429(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006897"(endocytosis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008277"(regulation of G protein-coupled receptor signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0071108"(protein K48-linked deubiquitination)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001607(Zinc finger, UBP-type)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018200|ensembl:ENSG00000136878(gene)|interpro:IPR028889|interpro:IPR035927|interpro:IPR038765|mint:Q9Y2K6|rcsb pdb:6KCZ|reactome:R-HSA-5689880|refseq:XP_011516463.1|refseq:XP_011516464.1|ensembl:ENSP00000313811|ensembl:ENSP00000351122|ensembl:ENSP00000361506|refseq:NP_001008563.2|refseq:NP_001103773.2|refseq:NP_006667.3|refseq:XP_005251722.1 - - comment:"author score: 29" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:LDXV9srMj1BL2CaSSot1Bn0/EW49606 rogid:5uvsgAipzkqnIHoUbjFfGR9vHS09606 rigid:PeLDjUQttTVEtpJCTmgCrrC39VQ false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HC52 intact:EBI-25401924 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 - psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:rs4x_rs4y1_rs4y2_human(display_short)|psi-mi:EBI-25401924(display_long) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477102|imex:IM-26985-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:1304"(molecule set) ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N - - - comment:P22090,P62701,Q8TD47|comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2021/09/28 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 - - false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HC52 uniprotkb:O00257 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397 psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477102|imex:IM-26985-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724 - - comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2021/09/28 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606 - false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HC52 uniprotkb:P78364 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 intact:EBI-725403|uniprotkb:Q8WVM3|uniprotkb:Q9BU63|uniprotkb:D3DUV4|ensembl:ENSP00000437659|ensembl:ENSP00000440674 psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:phc1_human(display_long)|uniprotkb:Early development regulatory protein 1(gene name synonym)|uniprotkb:PHC1(gene name)|psi-mi:PHC1(display_short)|uniprotkb:EDR1(gene name synonym)|uniprotkb:PH1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477102|imex:IM-26985-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N refseq:NP_004417.2|ensembl:ENSG00000111752(gene)|ensembl:ENST00000543824(transcript)|ensembl:ENST00000544916(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:P78364|rcsb pdb:2L8E|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|dip:DIP-44567N - - comment:"author score: 49" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2021/09/28 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 rogid:0dDjrgvWcP5Sx8h+qUj7awuM3ko9606 - false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HC52 uniprotkb:Q8NDX5 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 intact:EBI-1223801|uniprotkb:Q5HYF0|uniprotkb:Q6NSG2|uniprotkb:Q8NFT7|uniprotkb:Q8NFZ1|uniprotkb:Q8TBM2|uniprotkb:Q9H971|uniprotkb:Q9H9I4|uniprotkb:A2RRP9|ensembl:ENSP00000420271 psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:phc3_human(display_long)|uniprotkb:PHC3(gene name)|psi-mi:PHC3(display_short)|uniprotkb:EDR3(gene name synonym)|uniprotkb:PH3(gene name synonym)|uniprotkb:Homolog of polyhomeotic 3(gene name synonym)|uniprotkb:Early development regulatory protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477102|imex:IM-26985-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N refseq:NP_079223.3|refseq:NP_001295045.1|ensembl:ENSP00000420271|ensembl:ENST00000495893|ensembl:ENSP00000420294|ensembl:ENST00000497658|ensembl:ENSP00000420454|ensembl:ENSG00000173889(gene)|ensembl:ENST00000494943(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:Q8NDX5|rcsb pdb:4PZN|rcsb pdb:4PZO|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 - - comment:"author score: 51" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2021/09/28 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 rogid:hB1EMs+lCv19uuJ1O7+QiVCUoo89606 - false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HC52 uniprotkb:Q8IXK0 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 intact:EBI-713786|uniprotkb:Q8N306|uniprotkb:Q8TAG8|uniprotkb:A1L4Q1|uniprotkb:Q2TAL3|uniprotkb:Q5T0C1|uniprotkb:Q6NUJ6|uniprotkb:Q6ZQR1|uniprotkb:Q96BL4|uniprotkb:Q9Y4Y7|ensembl:ENSP00000257118|uniprotkb:D3DPR2|uniprotkb:A8KA40 psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:phc2_human(display_long)|uniprotkb:Early development regulatory protein 2(gene name synonym)|uniprotkb:PHC2(gene name)|psi-mi:PHC2(display_short)|uniprotkb:EDR2(gene name synonym)|uniprotkb:PH2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477102|imex:IM-26985-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N interpro:IPR038603|mint:Q8IXK0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR013761(Sterile alpha motif-type)|ensembl:ENSG00000134686(gene)|ensembl:ENST00000257118(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|refseq:NP_004418.2|refseq:NP_932157.1|refseq:XP_016856005.1|refseq:XP_016856006.1|refseq:XP_016856007.1|refseq:XP_005270627.1|dip:DIP-34464N - - comment:"author score: 56" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2021/09/28 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 rogid:7si/KU2tHoxviuCr70ncQERDWmY9606 - false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HC52 uniprotkb:P35227 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 intact:EBI-2129767|uniprotkb:A6NGD8|ensembl:ENSP00000478517|ensembl:ENSP00000478970|ensembl:ENSP00000482063|ensembl:ENSP00000482815|ensembl:ENSP00000488868|ensembl:ENSP00000488872 psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:pcgf2_human(display_long)|uniprotkb:PCGF2(gene name)|psi-mi:PCGF2(display_short)|uniprotkb:MEL18(gene name synonym)|uniprotkb:RNF110(gene name synonym)|uniprotkb:ZNF144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477102|imex:IM-26985-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N refseq:NP_009075.1|refseq:XP_016880505.1|refseq:XP_005257697.1|refseq:XP_005257698.1|refseq:XP_005257699.1|dip:DIP-41880N|ensembl:ENSG00000277258(gene)|ensembl:ENSG00000278644(gene)|ensembl:ENST00000610440(transcript)|ensembl:ENST00000611883(transcript)|ensembl:ENST00000616199(transcript)|ensembl:ENST00000620225(transcript)|ensembl:ENST00000631566(transcript)|ensembl:ENST00000631610(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35227|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-5617472|reactome:R-HSA-8953750 - - comment:"author score: 62" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2021/09/28 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 rogid:zppw56VrEl6gEFwtJMCN5cQkPxI9606 - false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HC52 uniprotkb:Q99496 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477102|imex:IM-26985-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 - - comment:"author score: 67" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2021/09/28 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 - false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HC52 uniprotkb:Q96GD3 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 intact:EBI-713793|uniprotkb:Q5VT76|uniprotkb:Q6IAJ4|uniprotkb:Q8WU48|uniprotkb:Q9UKM5|uniprotkb:Q9UKM6|ensembl:ENSP00000318094|ensembl:ENSP00000380359|uniprotkb:B4DRQ8 psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:scmh1_human(display_long)|uniprotkb:Sex comb on midleg homolog 1(gene name synonym)|uniprotkb:SCMH1(gene name)|psi-mi:SCMH1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477102|imex:IM-26985-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N refseq:XP_006710527.1|ensembl:ENSG00000010803(gene)|ensembl:ENST00000326197(transcript)|ensembl:ENST00000397174(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010369"(chromocenter)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|go:"GO:0005634"(nucleus)|interpro:IPR021987|interpro:IPR033763|interpro:IPR038348|mint:Q96GD3|rcsb pdb:2P0K|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|refseq:NP_001026864.1|refseq:NP_001165689.1|refseq:NP_001165690.1|refseq:NP_001165691.1|refseq:NP_001165692.1|refseq:NP_001165693.1|refseq:NP_036368.1|refseq:XP_016856188.1|refseq:XP_016856196.1|refseq:XP_011539335.1|refseq:XP_011539338.1 - - comment:"author score: 67" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2021/09/28 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 rogid:e39O++wYwPAUlKUeNfRurqnXbz09606 - false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HC52 uniprotkb:P35226 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 intact:EBI-2341576|uniprotkb:Q5T8Z3|uniprotkb:Q96F37|uniprotkb:Q16030|intact:EBI-28989037|ensembl:ENSP00000365851 psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:bmi1_human(display_long)|uniprotkb:BMI1(gene name)|psi-mi:BMI1(display_short)|uniprotkb:PCGF4(gene name synonym)|uniprotkb:RNF51(gene name synonym)|uniprotkb:Polycomb group RING finger protein 4(gene name synonym)|uniprotkb:RING finger protein 51(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477102|imex:IM-26985-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N refseq:NP_001190991.1|refseq:NP_005171.4|ensembl:ENSP00000365851|dip:DIP-41879N|ensembl:ENSG00000168283(gene)|ensembl:ENST00000376663(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006959"(humoral immune response)|go:"GO:0007379"(segment specification)|go:"GO:0007420"(brain development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35226|rcsb pdb:2H0D|rcsb pdb:2NA1|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:5FR6|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 - - comment:"author score: 87" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2021/09/28 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 rogid:ruyez2gHfd/si8gxYUDZzZ1L4689606 - false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96ES7 uniprotkb:Q5T6C5 intact:EBI-743117|ensembl:ENSP00000316114|uniprotkb:Q96MF5 intact:EBI-949168|ensembl:ENSP00000358886 psi-mi:sgf29_human(display_long)|uniprotkb:SGF29(gene name)|psi-mi:SGF29(display_short)|uniprotkb:CCDC101(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 101(gene name synonym)|uniprotkb:SAGA complex-associated factor 29(gene name synonym) psi-mi:at7l2_human(display_long)|uniprotkb:ATXN7L2(gene name)|psi-mi:ATXN7L2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477135|imex:IM-26985-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000176476(gene)|ensembl:ENST00000317058(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0016573"(histone acetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0071169"(establishment of protein localization to chromatin)|interpro:IPR010750(Protein of unknown function DUF1325)|interpro:IPR037802|mint:Q96ES7|rcsb pdb:3LX7|rcsb pdb:3ME9|refseq:NP_612423.1|rcsb pdb:3MEA|rcsb pdb:3MET|rcsb pdb:3MEU|rcsb pdb:3MEV|rcsb pdb:3MEW|rcsb pdb:5C0M|reactome:R-HSA-3214847 ensembl:ENSG00000162650(gene)|ensembl:ENST00000369870(transcript)|interpro:IPR013243(SCA7)|mint:Q5T6C5|refseq:NP_699171.3 - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:4uvy31cdeHtlQ4BHWSOLE8Szkq49606 rogid:kPIjJ2NIDAAHLvVnRNzSD61XZD89606 rigid:T+c0oKMaoCV2LP3oubnKMWmtD4s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96ES7 uniprotkb:Q01658 intact:EBI-743117|ensembl:ENSP00000316114|uniprotkb:Q96MF5 intact:EBI-750300|ensembl:ENSP00000359290|ensembl:ENSP00000359295 psi-mi:sgf29_human(display_long)|uniprotkb:SGF29(gene name)|psi-mi:SGF29(display_short)|uniprotkb:CCDC101(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 101(gene name synonym)|uniprotkb:SAGA complex-associated factor 29(gene name synonym) psi-mi:nc2b_human(display_long)|uniprotkb:Down-regulator of transcription 1(gene name synonym)|uniprotkb:TATA-binding protein-associated phosphoprotein(gene name synonym)|uniprotkb:Negative cofactor 2-beta(gene name synonym)|uniprotkb:DR1(gene name)|psi-mi:DR1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477135|imex:IM-26985-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000176476(gene)|ensembl:ENST00000317058(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0016573"(histone acetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0071169"(establishment of protein localization to chromatin)|interpro:IPR010750(Protein of unknown function DUF1325)|interpro:IPR037802|mint:Q96ES7|rcsb pdb:3LX7|rcsb pdb:3ME9|refseq:NP_612423.1|rcsb pdb:3MEA|rcsb pdb:3MET|rcsb pdb:3MEU|rcsb pdb:3MEV|rcsb pdb:3MEW|rcsb pdb:5C0M|reactome:R-HSA-3214847 refseq:NP_001929.1|ensembl:ENSG00000117505(gene)|ensembl:ENST00000370267(transcript)|ensembl:ENST00000370272(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0017054"(negative cofactor 2 complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051123"(RNA polymerase II preinitiation complex assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003958(Transcription factor CBF/NF-Y/archaeal histone)|interpro:IPR009072(Histone-fold)|interpro:IPR042225|mint:Q01658|rcsb pdb:1JFI|reactome:R-HSA-3214847 - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:4uvy31cdeHtlQ4BHWSOLE8Szkq49606 rogid:lrcYCVWbIkFU01ETSmd3cX++jLw9606 rigid:T+c0oKMaoCV2LP3oubnKMWmtD4s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96ES7 uniprotkb:P61964 intact:EBI-743117|ensembl:ENSP00000316114|uniprotkb:Q96MF5 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 psi-mi:sgf29_human(display_long)|uniprotkb:SGF29(gene name)|psi-mi:SGF29(display_short)|uniprotkb:CCDC101(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 101(gene name synonym)|uniprotkb:SAGA complex-associated factor 29(gene name synonym) psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477135|imex:IM-26985-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000176476(gene)|ensembl:ENST00000317058(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0016573"(histone acetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0071169"(establishment of protein localization to chromatin)|interpro:IPR010750(Protein of unknown function DUF1325)|interpro:IPR037802|mint:Q96ES7|rcsb pdb:3LX7|rcsb pdb:3ME9|refseq:NP_612423.1|rcsb pdb:3MEA|rcsb pdb:3MET|rcsb pdb:3MEU|rcsb pdb:3MEV|rcsb pdb:3MEW|rcsb pdb:5C0M|reactome:R-HSA-3214847 refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N - - comment:"author score: 29" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:4uvy31cdeHtlQ4BHWSOLE8Szkq49606 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rigid:T+c0oKMaoCV2LP3oubnKMWmtD4s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96ES7 uniprotkb:A6NNY8 intact:EBI-743117|ensembl:ENSP00000316114|uniprotkb:Q96MF5 intact:EBI-2512262|intact:EBI-28988282|ensembl:ENSP00000483631 psi-mi:sgf29_human(display_long)|uniprotkb:SGF29(gene name)|psi-mi:SGF29(display_short)|uniprotkb:CCDC101(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 101(gene name synonym)|uniprotkb:SAGA complex-associated factor 29(gene name synonym) psi-mi:ubp27_human(display_long)|uniprotkb:USP27X(gene name)|psi-mi:USP27X(display_short)|uniprotkb:USP22L(gene name synonym)|uniprotkb:USP27(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 27(gene name synonym)|uniprotkb:Deubiquitinating enzyme 27(gene name synonym)|uniprotkb:X-linked ubiquitin carboxyl-terminal hydrolase 27(gene name synonym)|uniprotkb:Ubiquitin carboxyl-terminal hydrolase 22-like(gene name synonym)|uniprotkb:Ubiquitin thioesterase 27(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477135|imex:IM-26985-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000176476(gene)|ensembl:ENST00000317058(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0016573"(histone acetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0071169"(establishment of protein localization to chromatin)|interpro:IPR010750(Protein of unknown function DUF1325)|interpro:IPR037802|mint:Q96ES7|rcsb pdb:3LX7|rcsb pdb:3ME9|refseq:NP_612423.1|rcsb pdb:3MEA|rcsb pdb:3MET|rcsb pdb:3MEU|rcsb pdb:3MEV|rcsb pdb:3MEW|rcsb pdb:5C0M|reactome:R-HSA-3214847 ensembl:ENSG00000273820(gene)|ensembl:ENST00000621775(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0050821"(protein stabilization)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765|mint:A6NNY8|refseq:NP_001138545.1|ensembl:ENSP00000483631 - - comment:"author score: 30" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:4uvy31cdeHtlQ4BHWSOLE8Szkq49606 rogid:8a2mLpB/MpBNttLlpgcl9dTQz/M9606 rigid:T+c0oKMaoCV2LP3oubnKMWmtD4s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96ES7 uniprotkb:Q9Y2I8 intact:EBI-743117|ensembl:ENSP00000316114|uniprotkb:Q96MF5 intact:EBI-355115|uniprotkb:Q5SW03|uniprotkb:Q9NTJ6|uniprotkb:D3DRQ7|intact:EBI-28986644|ensembl:ENSP00000263150|ensembl:ENSP00000350954|intact:EBI-745697|uniprotkb:A8K976|uniprotkb:Q8WVG2 psi-mi:sgf29_human(display_long)|uniprotkb:SGF29(gene name)|psi-mi:SGF29(display_short)|uniprotkb:CCDC101(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 101(gene name synonym)|uniprotkb:SAGA complex-associated factor 29(gene name synonym) psi-mi:wdr37_human(display_long)|uniprotkb:WDR37(gene name)|psi-mi:WDR37(display_short)|uniprotkb:KIAA0982(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477135|imex:IM-26985-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000176476(gene)|ensembl:ENST00000317058(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0016573"(histone acetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0071169"(establishment of protein localization to chromatin)|interpro:IPR010750(Protein of unknown function DUF1325)|interpro:IPR037802|mint:Q96ES7|rcsb pdb:3LX7|rcsb pdb:3ME9|refseq:NP_612423.1|rcsb pdb:3MEA|rcsb pdb:3MET|rcsb pdb:3MEU|rcsb pdb:3MEV|rcsb pdb:3MEW|rcsb pdb:5C0M|reactome:R-HSA-3214847 refseq:NP_054742.2|ensembl:ENSP00000263150|ensembl:ENSP00000350954|ensembl:ENSG00000047056(gene)|ensembl:ENST00000263150(transcript)|ensembl:ENST00000358220(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0030687"(preribosome, large subunit precursor)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9Y2I8 - - comment:"author score: 35" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:4uvy31cdeHtlQ4BHWSOLE8Szkq49606 rogid:GdQ5EnVwnp9rhvc3coyNbwhpO+c9606 rigid:T+c0oKMaoCV2LP3oubnKMWmtD4s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96ES7 uniprotkb:Q12962 intact:EBI-743117|ensembl:ENSP00000316114|uniprotkb:Q96MF5 intact:EBI-708376|uniprotkb:O00703|uniprotkb:Q13175|uniprotkb:Q6FH13|ensembl:ENSP00000299424 psi-mi:sgf29_human(display_long)|uniprotkb:SGF29(gene name)|psi-mi:SGF29(display_short)|uniprotkb:CCDC101(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 101(gene name synonym)|uniprotkb:SAGA complex-associated factor 29(gene name synonym) psi-mi:taf10_human(display_long)|uniprotkb:Transcription initiation factor TFIID 30 kDa subunit(gene name synonym)|uniprotkb:STAF28(gene name synonym)|uniprotkb:TAF10(gene name)|psi-mi:TAF10(display_short)|uniprotkb:TAF2H(gene name synonym)|uniprotkb:TAFII30(gene name synonym)|uniprotkb:TAF2A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477135|imex:IM-26985-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000176476(gene)|ensembl:ENST00000317058(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0016573"(histone acetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0071169"(establishment of protein localization to chromatin)|interpro:IPR010750(Protein of unknown function DUF1325)|interpro:IPR037802|mint:Q96ES7|rcsb pdb:3LX7|rcsb pdb:3ME9|refseq:NP_612423.1|rcsb pdb:3MEA|rcsb pdb:3MET|rcsb pdb:3MEU|rcsb pdb:3MEV|rcsb pdb:3MEW|rcsb pdb:5C0M|reactome:R-HSA-3214847 refseq:NP_006275.1|dip:DIP-297N|ensembl:ENSG00000166337(gene)|ensembl:ENST00000299424(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000125"|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006915"(apoptotic process)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0034622"|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR003923(Transcription initiation factor TFIID, 23-30 kDa subunit)|mint:Q12962|rcsb pdb:2F69|rcsb pdb:3M53|rcsb pdb:3M54|rcsb pdb:3M55|rcsb pdb:3M56|rcsb pdb:3M57|rcsb pdb:3M58|rcsb pdb:3M59|rcsb pdb:3M5A|rcsb pdb:4J7F|rcsb pdb:4J7I|rcsb pdb:4J83|rcsb pdb:4J8O|rcsb pdb:4WV4|rcsb pdb:5EG2|rcsb pdb:6MZC|rcsb pdb:6MZD|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGF|rcsb pdb:7EGG|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-3214847|reactome:R-HSA-5689880|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042 - - comment:"author score: 38" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:4uvy31cdeHtlQ4BHWSOLE8Szkq49606 rogid:8HFLtF8faq1WlDk5+r4B/+4Ldeg9606 rigid:T+c0oKMaoCV2LP3oubnKMWmtD4s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96ES7 uniprotkb:Q9H8E8 intact:EBI-743117|ensembl:ENSP00000316114|uniprotkb:Q96MF5 intact:EBI-750907|uniprotkb:Q96GW6|uniprotkb:Q96IH3|uniprotkb:Q9HBF0|uniprotkb:Q9UIY5|uniprotkb:A2A2I5|ensembl:ENSP00000366909|ensembl:ENSP00000392318|ensembl:ENSP00000424752|ensembl:ENSP00000503109|ensembl:ENSP00000503493|ensembl:ENSP00000504050|ensembl:ENSP00000504276 psi-mi:sgf29_human(display_long)|uniprotkb:SGF29(gene name)|psi-mi:SGF29(display_short)|uniprotkb:CCDC101(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 101(gene name synonym)|uniprotkb:SAGA complex-associated factor 29(gene name synonym) psi-mi:csr2b_human(display_long)|uniprotkb:KAT14(gene name)|psi-mi:KAT14(display_short)|uniprotkb:ADA2A-containing complex subunit 2(gene name synonym)|uniprotkb:CRP2-binding partner(gene name synonym)|uniprotkb:CSRP2BP(gene name synonym)|uniprotkb:Lysine acetyltransferase 14(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477135|imex:IM-26985-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000176476(gene)|ensembl:ENST00000317058(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0016573"(histone acetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0071169"(establishment of protein localization to chromatin)|interpro:IPR010750(Protein of unknown function DUF1325)|interpro:IPR037802|mint:Q96ES7|rcsb pdb:3LX7|rcsb pdb:3ME9|refseq:NP_612423.1|rcsb pdb:3MEA|rcsb pdb:3MET|rcsb pdb:3MEU|rcsb pdb:3MEV|rcsb pdb:3MEW|rcsb pdb:5C0M|reactome:R-HSA-3214847 refseq:NP_065397.3|ensembl:ENSG00000149474(gene)|ensembl:ENST00000377681(transcript)|ensembl:ENST00000435364(transcript)|ensembl:ENST00000464792(transcript)|ensembl:ENST00000676935(transcript)|ensembl:ENST00000677174(transcript)|ensembl:ENST00000677266(transcript)|ensembl:ENST00000678772(transcript)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0030274"(LIM domain binding)|go:"GO:0043966"(histone H3 acetylation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR037829|mint:Q9H8E8|reactome:R-HSA-3214847 - - comment:"author score: 48" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:4uvy31cdeHtlQ4BHWSOLE8Szkq49606 rogid:/Udl5yqzzDQ9jsscSVJlzcGd/VI9606 rigid:T+c0oKMaoCV2LP3oubnKMWmtD4s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96ES7 uniprotkb:Q92830 intact:EBI-743117|ensembl:ENSP00000316114|uniprotkb:Q96MF5 intact:EBI-477622|uniprotkb:Q9UCW1|uniprotkb:Q8N1A2|ensembl:ENSP00000225916 psi-mi:sgf29_human(display_long)|uniprotkb:SGF29(gene name)|psi-mi:SGF29(display_short)|uniprotkb:CCDC101(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 101(gene name synonym)|uniprotkb:SAGA complex-associated factor 29(gene name synonym) psi-mi:kat2a_human(display_long)|uniprotkb:Histone acetyltransferase GCN5(gene name synonym)|uniprotkb:STAF97(gene name synonym)|uniprotkb:General control of amino acid synthesis protein 5-like 2(gene name synonym)|uniprotkb:GCN5L2(gene name synonym)|uniprotkb:Lysine acetyltransferase 2A(gene name synonym)|uniprotkb:KAT2A(gene name)|psi-mi:KAT2A(display_short)|uniprotkb:GCN5(gene name synonym)|uniprotkb:Histone succinyltransferase KAT2A(gene name synonym)|uniprotkb:Histone glutaryltransferase KAT2A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477135|imex:IM-26985-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000176476(gene)|ensembl:ENST00000317058(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0016573"(histone acetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0071169"(establishment of protein localization to chromatin)|interpro:IPR010750(Protein of unknown function DUF1325)|interpro:IPR037802|mint:Q96ES7|rcsb pdb:3LX7|rcsb pdb:3ME9|refseq:NP_612423.1|rcsb pdb:3MEA|rcsb pdb:3MET|rcsb pdb:3MEU|rcsb pdb:3MEV|rcsb pdb:3MEW|rcsb pdb:5C0M|reactome:R-HSA-3214847 refseq:NP_066564.2|ensembl:ENSG00000108773(gene)|ensembl:ENST00000225916(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048312"(intracellular distribution of mitochondria)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0060173"(limb development)|go:"GO:0061035"(regulation of cartilage development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071929"(alpha-tubulin acetylation)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106077"(histone succinylation)|go:"GO:0106078"(histone succinyltransferase activity)|go:"GO:0106227"(peptidyl-lysine glutarylation)|go:"GO:0106229"(histone glutaryltransferase activity)|go:"GO:1903010"(regulation of bone development)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000727"(positive regulation of cardiac muscle cell differentiation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|interpro:IPR036427|interpro:IPR037800|mint:Q92830|rcsb pdb:1F68|rcsb pdb:1Z4R|rcsb pdb:3D7C|rcsb pdb:5H84|rcsb pdb:5H86|rcsb pdb:5MLJ|rcsb pdb:5TRL|rcsb pdb:5TRM|rcsb pdb:6J3P|reactome:R-HSA-1912408|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214847|reactome:R-HSA-350054|reactome:R-HSA-5250924|reactome:R-HSA-5689880|reactome:R-HSA-73762|reactome:R-HSA-8941856|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007507"(heart development)|go:"GO:0007616"(long-term memory)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021537"(telencephalon development)|go:"GO:0022037"(metencephalon development)|go:"GO:0030901"(midbrain development)|go:"GO:0030914"|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043997"("histone acetyltransferase activity (H4-K12 specific)")|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045589"(regulation of regulatory T cell differentiation)|reactome:R-HSA-9013508|reactome:R-HSA-9013695|refseq:XP_016879937.1|dip:DIP-28146N - - comment:"author score: 51" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:4uvy31cdeHtlQ4BHWSOLE8Szkq49606 rogid:PwDTlmU+caK91Xbiv7xm4xejZok9606 rigid:T+c0oKMaoCV2LP3oubnKMWmtD4s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96ES7 uniprotkb:O75486 intact:EBI-743117|ensembl:ENSP00000316114|uniprotkb:Q96MF5 intact:EBI-896640|uniprotkb:A6NKG9|uniprotkb:O76066|uniprotkb:Q5TAV9|uniprotkb:B2R9Q5|uniprotkb:Q86VN7|intact:EBI-11061133|ensembl:ENSP00000360514|ensembl:ENSP00000436411 psi-mi:sgf29_human(display_long)|uniprotkb:SGF29(gene name)|psi-mi:SGF29(display_short)|uniprotkb:CCDC101(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 101(gene name synonym)|uniprotkb:SAGA complex-associated factor 29(gene name synonym) psi-mi:supt3_human(display_long)|uniprotkb:SUPT3H(gene name)|psi-mi:SUPT3H(display_short)|uniprotkb:SPT3(gene name synonym)|uniprotkb:SPT3-like protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477135|imex:IM-26985-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000176476(gene)|ensembl:ENST00000317058(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0016573"(histone acetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0071169"(establishment of protein localization to chromatin)|interpro:IPR010750(Protein of unknown function DUF1325)|interpro:IPR037802|mint:Q96ES7|rcsb pdb:3LX7|rcsb pdb:3ME9|refseq:NP_612423.1|rcsb pdb:3MEA|rcsb pdb:3MET|rcsb pdb:3MEU|rcsb pdb:3MEV|rcsb pdb:3MEW|rcsb pdb:5C0M|reactome:R-HSA-3214847 refseq:XP_016866861.1|refseq:NP_003590.1|refseq:NP_852001.1|refseq:XP_016866860.1|dip:DIP-28148N|ensembl:ENSG00000196284(gene)|ensembl:ENST00000371459(transcript)|ensembl:ENST00000475057(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR003195(Transcription initiation factor IID, 18 kDa subunit)|interpro:IPR009072(Histone-fold)|mint:O75486|reactome:R-HSA-3214847 - - comment:"author score: 58" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:4uvy31cdeHtlQ4BHWSOLE8Szkq49606 rogid:P+62Ufs6GyoQYKCpbNaab5KzYOc9606 rigid:T+c0oKMaoCV2LP3oubnKMWmtD4s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96ES7 uniprotkb:Q16594 intact:EBI-743117|ensembl:ENSP00000316114|uniprotkb:Q96MF5 intact:EBI-712521|ensembl:ENSP00000370193|ensembl:ENSP00000421873|ensembl:ENSP00000477611|ensembl:ENSP00000477750|ensembl:ENSP00000478935|ensembl:ENSP00000217893|uniprotkb:Q5U0D1|uniprotkb:Q9BTS1|uniprotkb:D3DWA3|intact:EBI-8645823|intact:MINT-8163548 psi-mi:sgf29_human(display_long)|uniprotkb:SGF29(gene name)|psi-mi:SGF29(display_short)|uniprotkb:CCDC101(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 101(gene name synonym)|uniprotkb:SAGA complex-associated factor 29(gene name synonym) psi-mi:taf9_human(display_long)|uniprotkb:Transcription initiation factor TFIID 31 kDa subunit(gene name synonym)|uniprotkb:Transcription initiation factor TFIID 32 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II TBP-associated factor subunit G(gene name synonym)|uniprotkb:STAF31/32(gene name synonym)|uniprotkb:TAF9(gene name)|psi-mi:TAF9(display_short)|uniprotkb:TAF2G(gene name synonym)|uniprotkb:TAFII31(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477135|imex:IM-26985-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000176476(gene)|ensembl:ENST00000317058(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0016573"(histone acetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0071169"(establishment of protein localization to chromatin)|interpro:IPR010750(Protein of unknown function DUF1325)|interpro:IPR037802|mint:Q96ES7|rcsb pdb:3LX7|rcsb pdb:3ME9|refseq:NP_612423.1|rcsb pdb:3MEA|rcsb pdb:3MET|rcsb pdb:3MEU|rcsb pdb:3MEV|rcsb pdb:3MEW|rcsb pdb:5C0M|reactome:R-HSA-3214847 ensembl:ENST00000217893(transcript)|ensembl:ENST00000328663(transcript)|ensembl:ENST00000506736(transcript)|ensembl:ENST00000615404(transcript)|ensembl:ENST00000616867(transcript)|ensembl:ENST00000617893(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000125"|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0030914"|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0070761"(pre-snoRNP complex)|go:"GO:0071339"(MLL1 complex)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|interpro:IPR003162(Transcription factor TAFII-31)|interpro:IPR009072(Histone-fold)|mint:Q16594|rcsb pdb:6F3T|rcsb pdb:6MZC|rcsb pdb:6MZD|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGF|rcsb pdb:7EGG|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-3214847|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-6807505|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042|ensembl:ENSG00000273841(gene)|ensembl:ENSG00000276463(gene)|refseq:NP_001015892.1|refseq:NP_003178.1|dip:DIP-435N - - comment:"author score: 61" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:4uvy31cdeHtlQ4BHWSOLE8Szkq49606 rogid:Drikn9IwpWQXbTTXGqwf1hlRNE09606 rigid:T+c0oKMaoCV2LP3oubnKMWmtD4s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96ES7 uniprotkb:Q6P2E9 intact:EBI-743117|ensembl:ENSP00000316114|uniprotkb:Q96MF5 intact:EBI-1006038|uniprotkb:Q13025|uniprotkb:Q13826|uniprotkb:Q6ZR12|uniprotkb:Q7Z6H7|uniprotkb:A6NGM1|uniprotkb:A8K4T4|ensembl:ENSP00000351811 psi-mi:sgf29_human(display_long)|uniprotkb:SGF29(gene name)|psi-mi:SGF29(display_short)|uniprotkb:CCDC101(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 101(gene name synonym)|uniprotkb:SAGA complex-associated factor 29(gene name synonym) psi-mi:edc4_human(display_long)|uniprotkb:Human enhancer of decapping large subunit(gene name synonym)|uniprotkb:Autoantigen Ge-1(gene name synonym)|uniprotkb:Autoantigen RCD-8(gene name synonym)|uniprotkb:EDC4(gene name)|psi-mi:EDC4(display_short)|uniprotkb:HEDLS(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477135|imex:IM-26985-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000176476(gene)|ensembl:ENST00000317058(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0016573"(histone acetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0071169"(establishment of protein localization to chromatin)|interpro:IPR010750(Protein of unknown function DUF1325)|interpro:IPR037802|mint:Q96ES7|rcsb pdb:3LX7|rcsb pdb:3ME9|refseq:NP_612423.1|rcsb pdb:3MEA|rcsb pdb:3MET|rcsb pdb:3MEU|rcsb pdb:3MEV|rcsb pdb:3MEW|rcsb pdb:5C0M|reactome:R-HSA-3214847 ensembl:ENSG00000038358(gene)|interpro:IPR036322|mint:Q6P2E9|reactome:R-HSA-430039|ensembl:ENST00000358933(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR032401|refseq:NP_055144.3|dip:DIP-31192N - - comment:"author score: 62" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:4uvy31cdeHtlQ4BHWSOLE8Szkq49606 rogid:V5obZo71xmJbNRv5fc+o7wNdb+Y9606 rigid:T+c0oKMaoCV2LP3oubnKMWmtD4s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96ES7 uniprotkb:O75478 intact:EBI-743117|ensembl:ENSP00000316114|uniprotkb:Q96MF5 intact:EBI-742268|uniprotkb:A8MVD0|uniprotkb:B3KMU9|uniprotkb:Q9UCW2|uniprotkb:Q9UP49|intact:EBI-1204772|uniprotkb:Q9BVJ0|ensembl:ENSP00000481283|ensembl:ENSP00000482484|ensembl:ENSP00000488016 psi-mi:sgf29_human(display_long)|uniprotkb:SGF29(gene name)|psi-mi:SGF29(display_short)|uniprotkb:CCDC101(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 101(gene name synonym)|uniprotkb:SAGA complex-associated factor 29(gene name synonym) psi-mi:tad2a_human(display_long)|uniprotkb:TADA2A(gene name)|psi-mi:TADA2A(display_short)|uniprotkb:TADA2L(gene name synonym)|uniprotkb:Transcriptional adapter 2-like(gene name synonym)|uniprotkb:KL04P(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477135|imex:IM-26985-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000176476(gene)|ensembl:ENST00000317058(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0016573"(histone acetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0071169"(establishment of protein localization to chromatin)|interpro:IPR010750(Protein of unknown function DUF1325)|interpro:IPR037802|mint:Q96ES7|rcsb pdb:3LX7|rcsb pdb:3ME9|refseq:NP_612423.1|rcsb pdb:3MEA|rcsb pdb:3MET|rcsb pdb:3MEU|rcsb pdb:3MEV|rcsb pdb:3MEW|rcsb pdb:5C0M|reactome:R-HSA-3214847 refseq:NP_001159577.2|refseq:NP_001278847.1|refseq:NP_001479.4|refseq:NP_597683.3|go:"GO:0000125"|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0070461"(SAGA-type complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|mint:O75478|rcsb pdb:1X41|reactome:R-HSA-3214847|ensembl:ENST00000633468(transcript)|ensembl:ENSG00000277104(gene)|ensembl:ENST00000617828(transcript)|ensembl:ENST00000622522(transcript)|dip:DIP-28151N - - comment:"author score: 67" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:4uvy31cdeHtlQ4BHWSOLE8Szkq49606 rogid:GoQFsH/fQmhFkH04dCJrMWwZH589606 rigid:T+c0oKMaoCV2LP3oubnKMWmtD4s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96ES7 uniprotkb:Q14CW9 intact:EBI-743117|ensembl:ENSP00000316114|uniprotkb:Q96MF5 intact:EBI-949215|ensembl:ENSP00000374035|ensembl:ENSP00000465614|uniprotkb:Q96N40|uniprotkb:Q9NPU5|uniprotkb:Q8IY68 psi-mi:sgf29_human(display_long)|uniprotkb:SGF29(gene name)|psi-mi:SGF29(display_short)|uniprotkb:CCDC101(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 101(gene name synonym)|uniprotkb:SAGA complex-associated factor 29(gene name synonym) psi-mi:at7l3_human(display_long)|uniprotkb:ATXN7L3(gene name)|psi-mi:ATXN7L3(display_short)|uniprotkb:SAGA-associated factor 11 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477135|imex:IM-26985-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000176476(gene)|ensembl:ENST00000317058(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0016573"(histone acetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0071169"(establishment of protein localization to chromatin)|interpro:IPR010750(Protein of unknown function DUF1325)|interpro:IPR037802|mint:Q96ES7|rcsb pdb:3LX7|rcsb pdb:3ME9|refseq:NP_612423.1|rcsb pdb:3MEA|rcsb pdb:3MET|rcsb pdb:3MEU|rcsb pdb:3MEV|rcsb pdb:3MEW|rcsb pdb:5C0M|reactome:R-HSA-3214847 ensembl:ENSG00000087152(gene)|ensembl:ENST00000389384(transcript)|ensembl:ENST00000587097(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071819"(DUBm complex)|interpro:IPR013243(SCA7)|interpro:IPR013246(Sgf11, transcriptional regulation)|mint:Q14CW9|rcsb pdb:2KKT|reactome:R-HSA-3214847|refseq:NP_001092303.1|refseq:NP_064603.1|refseq:XP_016880374.1|refseq:XP_016880375.1 - - comment:"author score: 67" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:4uvy31cdeHtlQ4BHWSOLE8Szkq49606 rogid:r0Yw6RIZ9DbDlu2xE5hOFPlvk849606 rigid:T+c0oKMaoCV2LP3oubnKMWmtD4s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96ES7 uniprotkb:Q9Y4A5 intact:EBI-743117|ensembl:ENSP00000316114|uniprotkb:Q96MF5 intact:EBI-399128|uniprotkb:O75218|uniprotkb:Q9Y631|uniprotkb:Q9Y6H4|uniprotkb:A4D265|ensembl:ENSP00000352925 psi-mi:sgf29_human(display_long)|uniprotkb:SGF29(gene name)|psi-mi:SGF29(display_short)|uniprotkb:CCDC101(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 101(gene name synonym)|uniprotkb:SAGA complex-associated factor 29(gene name synonym) psi-mi:trrap_human(display_long)|uniprotkb:TRRAP(gene name)|psi-mi:TRRAP(display_short)|uniprotkb:PAF400(gene name synonym)|uniprotkb:350/400 kDa PCAF-associated factor(gene name synonym)|uniprotkb:STAF40(gene name synonym)|uniprotkb:Tra1 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477135|imex:IM-26985-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000176476(gene)|ensembl:ENST00000317058(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0016573"(histone acetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0071169"(establishment of protein localization to chromatin)|interpro:IPR010750(Protein of unknown function DUF1325)|interpro:IPR037802|mint:Q96ES7|rcsb pdb:3LX7|rcsb pdb:3ME9|refseq:NP_612423.1|rcsb pdb:3MEA|rcsb pdb:3MET|rcsb pdb:3MEU|rcsb pdb:3MEV|rcsb pdb:3MEW|rcsb pdb:5C0M|reactome:R-HSA-3214847 refseq:NP_003487.1|ensembl:ENSG00000196367(gene)|ensembl:ENST00000359863(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000125"|go:"GO:0000812"(Swr1 complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006281"(DNA repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016310"(phosphorylation)|go:"GO:0016573"(histone acetylation)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR003151(PIK-related kinase, FAT)|interpro:IPR003152(PIK-related kinase, FATC)|interpro:IPR011009(Protein kinase-like)|interpro:IPR014009(PIK-related kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033317|mint:Q9Y4A5|reactome:R-HSA-201722|reactome:R-HSA-3214847|reactome:R-HSA-5689880|refseq:NP_001231509.1|dip:DIP-28149N - - comment:"author score: 69" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:4uvy31cdeHtlQ4BHWSOLE8Szkq49606 rogid:bGoQLXxMT0zZ0jVW+2s4hUwnBA49606 rigid:T+c0oKMaoCV2LP3oubnKMWmtD4s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96ES7 uniprotkb:Q8NEM7 intact:EBI-743117|ensembl:ENSP00000316114|uniprotkb:Q96MF5 intact:EBI-946984|uniprotkb:Q71RF3|uniprotkb:Q9Y6A6|ensembl:ENSP00000218894|uniprotkb:E7ER46 psi-mi:sgf29_human(display_long)|uniprotkb:SGF29(gene name)|psi-mi:SGF29(display_short)|uniprotkb:CCDC101(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 101(gene name synonym)|uniprotkb:SAGA complex-associated factor 29(gene name synonym) psi-mi:sp20h_human(display_long)|uniprotkb:SUPT20H(gene name)|psi-mi:SUPT20H(display_short)|uniprotkb:C13orf19(gene name synonym)|uniprotkb:FAM48A(gene name synonym)|uniprotkb:p38-interacting protein(gene name synonym)|uniprotkb:FP757(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477135|imex:IM-26985-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000176476(gene)|ensembl:ENST00000317058(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0016573"(histone acetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0071169"(establishment of protein localization to chromatin)|interpro:IPR010750(Protein of unknown function DUF1325)|interpro:IPR037802|mint:Q96ES7|rcsb pdb:3LX7|rcsb pdb:3ME9|refseq:NP_612423.1|rcsb pdb:3MEA|rcsb pdb:3MET|rcsb pdb:3MEU|rcsb pdb:3MEV|rcsb pdb:3MEW|rcsb pdb:5C0M|reactome:R-HSA-3214847 refseq:NP_001265409.1|refseq:NP_001265410.1|refseq:NP_001265411.1|refseq:NP_001014308.2|refseq:NP_060039.1|ensembl:ENSG00000102710(gene)|ensembl:ENST00000350612(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006914"(autophagy)|go:"GO:0007369"(gastrulation)|go:"GO:0070461"(SAGA-type complex)|interpro:IPR021950|mint:Q8NEM7|reactome:R-HSA-3214847 - - comment:"author score: 77" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:4uvy31cdeHtlQ4BHWSOLE8Szkq49606 rogid:7s9ChKIewCopRWC7otwhnH6hYEs9606 rigid:T+c0oKMaoCV2LP3oubnKMWmtD4s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96ES7 uniprotkb:Q8IYH5 intact:EBI-743117|ensembl:ENSP00000316114|uniprotkb:Q96MF5 intact:EBI-2795524|uniprotkb:B7WPC6|uniprotkb:Q6N004|uniprotkb:Q6N070|uniprotkb:Q8IYP0|uniprotkb:Q8IYR1|uniprotkb:Q8TEK4|uniprotkb:Q9Y4U0|ensembl:ENSP00000359837 psi-mi:sgf29_human(display_long)|uniprotkb:SGF29(gene name)|psi-mi:SGF29(display_short)|uniprotkb:CCDC101(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 101(gene name synonym)|uniprotkb:SAGA complex-associated factor 29(gene name synonym) psi-mi:zzz3_human(display_long)|uniprotkb:ZZZ3(gene name)|psi-mi:ZZZ3(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477135|imex:IM-26985-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000176476(gene)|ensembl:ENST00000317058(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0016573"(histone acetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0071169"(establishment of protein localization to chromatin)|interpro:IPR010750(Protein of unknown function DUF1325)|interpro:IPR037802|mint:Q96ES7|rcsb pdb:3LX7|rcsb pdb:3ME9|refseq:NP_612423.1|rcsb pdb:3MEA|rcsb pdb:3MET|rcsb pdb:3MEU|rcsb pdb:3MEV|rcsb pdb:3MEW|rcsb pdb:5C0M|reactome:R-HSA-3214847 refseq:NP_001295166.1|refseq:NP_056349.1|refseq:XP_016856459.1|refseq:XP_005270782.1|refseq:XP_005270783.1|refseq:XP_005270784.1|refseq:XP_005270786.1|ensembl:ENSG00000036549(gene)|ensembl:ENST00000370801(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR037830|interpro:IPR041981|interpro:IPR043145|rcsb pdb:2FC7|rcsb pdb:2YUM|rcsb pdb:6E83|rcsb pdb:6E86|reactome:R-HSA-3214847|mint:Q8IYH5|dip:DIP-47289N - - comment:"author score: 78" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:4uvy31cdeHtlQ4BHWSOLE8Szkq49606 rogid:F8aEW+XePZMAIrIAIDMEnBXdSBo9606 rigid:T+c0oKMaoCV2LP3oubnKMWmtD4s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96ES7 uniprotkb:Q9HBM6 intact:EBI-743117|ensembl:ENSP00000316114|uniprotkb:Q96MF5 intact:EBI-751601|uniprotkb:Q9Y2S3|uniprotkb:B2RUZ9|ensembl:ENSP00000339917 psi-mi:sgf29_human(display_long)|uniprotkb:SGF29(gene name)|psi-mi:SGF29(display_short)|uniprotkb:CCDC101(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 101(gene name synonym)|uniprotkb:SAGA complex-associated factor 29(gene name synonym) psi-mi:taf9b_human(display_long)|uniprotkb:Transcription initiation factor TFIID subunit 9-like(gene name synonym)|uniprotkb:Transcription-associated factor TAFII31L(gene name synonym)|uniprotkb:Neuronal cell death-related protein 7(gene name synonym)|uniprotkb:TAF9B(gene name)|psi-mi:TAF9B(display_short)|uniprotkb:TAF9L(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477135|imex:IM-26985-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000176476(gene)|ensembl:ENST00000317058(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0016573"(histone acetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0071169"(establishment of protein localization to chromatin)|interpro:IPR010750(Protein of unknown function DUF1325)|interpro:IPR037802|mint:Q96ES7|rcsb pdb:3LX7|rcsb pdb:3ME9|refseq:NP_612423.1|rcsb pdb:3MEA|rcsb pdb:3MET|rcsb pdb:3MEU|rcsb pdb:3MEV|rcsb pdb:3MEW|rcsb pdb:5C0M|reactome:R-HSA-3214847 refseq:NP_057059.2|ensembl:ENSG00000187325(gene)|ensembl:ENST00000341864(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050821"(protein stabilization)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|interpro:IPR003162(Transcription factor TAFII-31)|interpro:IPR009072(Histone-fold)|mint:Q9HBM6|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-5689880|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042 - - comment:"author score: 82" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:4uvy31cdeHtlQ4BHWSOLE8Szkq49606 rogid:8+i5lmcx4OcgCEbk2F9MS8bYhos9606 rigid:T+c0oKMaoCV2LP3oubnKMWmtD4s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96ES7 uniprotkb:Q92831 intact:EBI-743117|ensembl:ENSP00000316114|uniprotkb:Q96MF5 intact:EBI-477430|uniprotkb:Q6NSK1|ensembl:ENSP00000263754 psi-mi:sgf29_human(display_long)|uniprotkb:SGF29(gene name)|psi-mi:SGF29(display_short)|uniprotkb:CCDC101(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 101(gene name synonym)|uniprotkb:SAGA complex-associated factor 29(gene name synonym) psi-mi:kat2b_human(display_long)|uniprotkb:P300/CBP-associated factor(gene name synonym)|uniprotkb:PCAF(gene name synonym)|uniprotkb:Lysine acetyltransferase 2B(gene name synonym)|uniprotkb:Histone acetyltransferase PCAF(gene name synonym)|uniprotkb:KAT2B(gene name)|psi-mi:KAT2B(display_short)|uniprotkb:Spermidine acetyltransferase KAT2B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477135|imex:IM-26985-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000176476(gene)|ensembl:ENST00000317058(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0016573"(histone acetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0071169"(establishment of protein localization to chromatin)|interpro:IPR010750(Protein of unknown function DUF1325)|interpro:IPR037802|mint:Q96ES7|rcsb pdb:3LX7|rcsb pdb:3ME9|refseq:NP_612423.1|rcsb pdb:3MEA|rcsb pdb:3MET|rcsb pdb:3MEU|rcsb pdb:3MEV|rcsb pdb:3MEW|rcsb pdb:5C0M|reactome:R-HSA-3214847 ensembl:ENSG00000114166(gene)|ensembl:ENST00000263754(transcript)|go:"GO:0000125"|go:"GO:0000776"(kinetochore)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004145"(diamine N-acetyltransferase activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0004468"(lysine N-acetyltransferase activity, acting on acetyl phosphate as donor)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006473"(protein acetylation)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0018076"(N-terminal peptidyl-lysine acetylation)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031672"(A band)|go:"GO:0031674"(I band)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|refseq:NP_003875.3|go:"GO:0043970"(histone H3-K9 acetylation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046600"(negative regulation of centriole replication)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060173"(limb development)|go:"GO:0061733"(peptide-lysine-N-acetyltransferase activity)|go:"GO:2000233"(negative regulation of rRNA processing)|interpro:IPR000182(GCN5-related N-acetyltransferase)|go:"GO:0043966"(histone H3 acetylation)|interpro:IPR001487(Bromodomain)|interpro:IPR009464(PCAF, N-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016376(Histone acetylase PCAF)|interpro:IPR018359|go:"GO:0042826"(histone deacetylase binding)|interpro:IPR036427|interpro:IPR037800|mint:Q92831|rcsb pdb:1CM0|rcsb pdb:1JM4|rcsb pdb:1N72|rcsb pdb:1WUG|rcsb pdb:1WUM|rcsb pdb:1ZS5|rcsb pdb:2RNW|rcsb pdb:2RNX|rcsb pdb:3GG3|rcsb pdb:4NSQ|rcsb pdb:5FDZ|rcsb pdb:5FE0|rcsb pdb:5FE1|rcsb pdb:5FE2|rcsb pdb:5FE3|rcsb pdb:5FE4|rcsb pdb:5FE5|rcsb pdb:5FE6|rcsb pdb:5FE7|rcsb pdb:5FE8|rcsb pdb:5FE9|rcsb pdb:5LVQ|rcsb pdb:5LVR|rcsb pdb:5MKX|rcsb pdb:6J3O|reactome:R-HSA-1912408|reactome:R-HSA-2032785|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214847|reactome:R-HSA-350054|reactome:R-HSA-5250924|reactome:R-HSA-5578768|reactome:R-HSA-5689901|reactome:R-HSA-73762|reactome:R-HSA-8936459|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|reactome:R-HSA-9018519|reactome:R-HSA-9617629|dip:DIP-29778N - - comment:"author score: 84" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:4uvy31cdeHtlQ4BHWSOLE8Szkq49606 rogid:g0Gzr/F28rlhpv1qBl+kMEuwlZI9606 rigid:T+c0oKMaoCV2LP3oubnKMWmtD4s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96ES7 uniprotkb:Q9NS73 intact:EBI-743117|ensembl:ENSP00000316114|uniprotkb:Q96MF5 intact:EBI-741953|uniprotkb:Q86TZ2|uniprotkb:Q96AS5|uniprotkb:Q9BS93|uniprotkb:Q9NZE1|ensembl:ENSP00000399718 psi-mi:sgf29_human(display_long)|uniprotkb:SGF29(gene name)|psi-mi:SGF29(display_short)|uniprotkb:CCDC101(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 101(gene name synonym)|uniprotkb:SAGA complex-associated factor 29(gene name synonym) psi-mi:mbip1_human(display_long)|uniprotkb:MAPK upstream kinase-binding inhibitory protein(gene name synonym)|uniprotkb:MBIP(gene name)|psi-mi:MBIP(display_short)|uniprotkb:BM-015(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477135|imex:IM-26985-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000176476(gene)|ensembl:ENST00000317058(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0016573"(histone acetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0071169"(establishment of protein localization to chromatin)|interpro:IPR010750(Protein of unknown function DUF1325)|interpro:IPR037802|mint:Q96ES7|rcsb pdb:3LX7|rcsb pdb:3ME9|refseq:NP_612423.1|rcsb pdb:3MEA|rcsb pdb:3MET|rcsb pdb:3MEU|rcsb pdb:3MEV|rcsb pdb:3MEW|rcsb pdb:5C0M|reactome:R-HSA-3214847 refseq:NP_001138363.1|refseq:NP_057670.2|ensembl:ENSG00000151332(gene)|ensembl:ENST00000416007(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR026062|mint:Q9NS73|reactome:R-HSA-3214847|go:"GO:0005654"(nucleoplasm)|refseq:NP_001295039.1 - - comment:"author score: 87" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:4uvy31cdeHtlQ4BHWSOLE8Szkq49606 rogid:PjaEuab6wwOyGImpNYFZfQ+TUvU9606 rigid:T+c0oKMaoCV2LP3oubnKMWmtD4s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96ES7 uniprotkb:Q9ULM3 intact:EBI-743117|ensembl:ENSP00000316114|uniprotkb:Q96MF5 intact:EBI-2795509|uniprotkb:A7E2B9|uniprotkb:Q641P6|uniprotkb:Q9NW96|uniprotkb:D3DNS9|ensembl:ENSP00000306983 psi-mi:sgf29_human(display_long)|uniprotkb:SGF29(gene name)|psi-mi:SGF29(display_short)|uniprotkb:CCDC101(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 101(gene name synonym)|uniprotkb:SAGA complex-associated factor 29(gene name synonym) psi-mi:yets2_human(display_long)|uniprotkb:YEATS2(gene name)|psi-mi:YEATS2(display_short)|uniprotkb:KIAA1197(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477135|imex:IM-26985-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000176476(gene)|ensembl:ENST00000317058(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0016573"(histone acetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0071169"(establishment of protein localization to chromatin)|interpro:IPR010750(Protein of unknown function DUF1325)|interpro:IPR037802|mint:Q96ES7|rcsb pdb:3LX7|rcsb pdb:3ME9|refseq:NP_612423.1|rcsb pdb:3MEA|rcsb pdb:3MET|rcsb pdb:3MEU|rcsb pdb:3MEV|rcsb pdb:3MEW|rcsb pdb:5C0M|reactome:R-HSA-3214847 refseq:NP_060493.3|refseq:XP_016862298.1|refseq:XP_016862299.1|reactome:R-HSA-3214847|rcsb pdb:6LSD|ensembl:ENST00000305135(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0072686"(mitotic spindle)|go:"GO:0140030"(modification-dependent protein binding)|interpro:IPR005033(YEATS)|interpro:IPR038704|mint:Q9ULM3|rcsb pdb:5IQL|ensembl:ENSG00000163872(gene)|rcsb pdb:5XNV - - comment:"author score: 90" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:4uvy31cdeHtlQ4BHWSOLE8Szkq49606 rogid:dbdCDssB6o5aHKaRdnvITi8b/v09606 rigid:T+c0oKMaoCV2LP3oubnKMWmtD4s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96ES7 uniprotkb:O94864 intact:EBI-743117|ensembl:ENSP00000316114|uniprotkb:Q96MF5 intact:EBI-722912|uniprotkb:Q6IB21|uniprotkb:Q9H2T6|uniprotkb:B4E3W3|ensembl:ENSP00000336750 psi-mi:sgf29_human(display_long)|uniprotkb:SGF29(gene name)|psi-mi:SGF29(display_short)|uniprotkb:CCDC101(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 101(gene name synonym)|uniprotkb:SAGA complex-associated factor 29(gene name synonym) psi-mi:st65g_human(display_long)|uniprotkb:SPTF-associated factor 65 gamma(gene name synonym)|uniprotkb:Suppressor of Ty 7-like(gene name synonym)|uniprotkb:Adenocarcinoma antigen ART1(gene name synonym)|uniprotkb:SUPT7L(gene name)|psi-mi:SUPT7L(display_short)|uniprotkb:KIAA0764(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477135|imex:IM-26985-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000176476(gene)|ensembl:ENST00000317058(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0016573"(histone acetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0071169"(establishment of protein localization to chromatin)|interpro:IPR010750(Protein of unknown function DUF1325)|interpro:IPR037802|mint:Q96ES7|rcsb pdb:3LX7|rcsb pdb:3ME9|refseq:NP_612423.1|rcsb pdb:3MEA|rcsb pdb:3MET|rcsb pdb:3MEU|rcsb pdb:3MEV|rcsb pdb:3MEW|rcsb pdb:5C0M|reactome:R-HSA-3214847 refseq:NP_001269658.1|refseq:NP_001269659.1|refseq:NP_001269660.1|refseq:NP_001269661.1|refseq:NP_055675.1|refseq:XP_005264729.1|ensembl:ENSG00000119760(gene)|ensembl:ENST00000337768(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0030914"|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|interpro:IPR006565(Bromodomain transcription factor)|interpro:IPR009072(Histone-fold)|interpro:IPR039460|mint:O94864|reactome:R-HSA-3214847 - - comment:"author score: 92" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:4uvy31cdeHtlQ4BHWSOLE8Szkq49606 rogid:v26YjDoNB/9ekC4xRZEm77Roruw9606 rigid:T+c0oKMaoCV2LP3oubnKMWmtD4s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96ES7 uniprotkb:Q96BN2 intact:EBI-743117|ensembl:ENSP00000316114|uniprotkb:Q96MF5 intact:EBI-2512236|ensembl:ENSP00000356848|uniprotkb:A8K4J9 psi-mi:sgf29_human(display_long)|uniprotkb:SGF29(gene name)|psi-mi:SGF29(display_short)|uniprotkb:CCDC101(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 101(gene name synonym)|uniprotkb:SAGA complex-associated factor 29(gene name synonym) psi-mi:tada1_human(display_long)|uniprotkb:TADA1(gene name)|psi-mi:TADA1(display_short)|uniprotkb:TADA1L(gene name synonym)|uniprotkb:Transcriptional adapter 1-like protein(gene name synonym)|uniprotkb:SPT3-associated factor 42(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477135|imex:IM-26985-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000176476(gene)|ensembl:ENST00000317058(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0016573"(histone acetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0071169"(establishment of protein localization to chromatin)|interpro:IPR010750(Protein of unknown function DUF1325)|interpro:IPR037802|mint:Q96ES7|rcsb pdb:3LX7|rcsb pdb:3ME9|refseq:NP_612423.1|rcsb pdb:3MEA|rcsb pdb:3MET|rcsb pdb:3MEU|rcsb pdb:3MEV|rcsb pdb:3MEW|rcsb pdb:5C0M|reactome:R-HSA-3214847 ensembl:ENSG00000152382(gene)|ensembl:ENST00000367874(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030914"|go:"GO:0043966"(histone H3 acetylation)|interpro:IPR024738|mint:Q96BN2|reactome:R-HSA-3214847|refseq:NP_444281.1 - - comment:"author score: 105" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:4uvy31cdeHtlQ4BHWSOLE8Szkq49606 rogid:07aGEsEjtD884LVJ6Jlj12+TdK49606 rigid:T+c0oKMaoCV2LP3oubnKMWmtD4s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96ES7 uniprotkb:Q86TJ2 intact:EBI-743117|ensembl:ENSP00000316114|uniprotkb:Q96MF5 intact:EBI-2512219|uniprotkb:Q6MZG9|uniprotkb:B3KSN0|uniprotkb:B3KU86|uniprotkb:A4QMR7|uniprotkb:A0AUJ8|ensembl:ENSP00000308022 psi-mi:sgf29_human(display_long)|uniprotkb:SGF29(gene name)|psi-mi:SGF29(display_short)|uniprotkb:CCDC101(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 101(gene name synonym)|uniprotkb:SAGA complex-associated factor 29(gene name synonym) psi-mi:tad2b_human(display_long)|uniprotkb:TADA2B(gene name)|psi-mi:TADA2B(display_short)|uniprotkb:ADA2B(gene name synonym)|uniprotkb:ADA2-like protein beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477135|imex:IM-26985-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000176476(gene)|ensembl:ENST00000317058(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0016573"(histone acetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0071169"(establishment of protein localization to chromatin)|interpro:IPR010750(Protein of unknown function DUF1325)|interpro:IPR037802|mint:Q96ES7|rcsb pdb:3LX7|rcsb pdb:3ME9|refseq:NP_612423.1|rcsb pdb:3MEA|rcsb pdb:3MET|rcsb pdb:3MEU|rcsb pdb:3MEV|rcsb pdb:3MEW|rcsb pdb:5C0M|reactome:R-HSA-3214847 refseq:XP_011511897.1|refseq:NP_689506.2|interpro:IPR016827(Transcriptional adaptor 2)|interpro:IPR017884|interpro:IPR017930|interpro:IPR036388|interpro:IPR041983|interpro:IPR043145|mint:Q86TJ2|reactome:R-HSA-3214847|reactome:R-HSA-5689880|interpro:IPR009057(Homeodomain-like)|ensembl:ENSG00000173011(gene)|ensembl:ENST00000310074(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030914"|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0070461"(SAGA-type complex)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding) - - comment:"author score: 114" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:4uvy31cdeHtlQ4BHWSOLE8Szkq49606 rogid:ShA8/bknqf6XcaEWL3YFWOz9s9c9606 rigid:T+c0oKMaoCV2LP3oubnKMWmtD4s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96ES7 uniprotkb:Q9Y6J9 intact:EBI-743117|ensembl:ENSP00000316114|uniprotkb:Q96MF5 intact:EBI-743984|uniprotkb:Q96HA6|uniprotkb:B2RAT0|ensembl:ENSP00000294168 psi-mi:sgf29_human(display_long)|uniprotkb:SGF29(gene name)|psi-mi:SGF29(display_short)|uniprotkb:CCDC101(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 101(gene name synonym)|uniprotkb:SAGA complex-associated factor 29(gene name synonym) psi-mi:taf6l_human(display_long)|uniprotkb:PCAF-associated factor 65-alpha(gene name synonym)|uniprotkb:TAF6L(gene name)|psi-mi:TAF6L(display_short)|uniprotkb:PAF65A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477135|imex:IM-26985-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000176476(gene)|ensembl:ENST00000317058(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0016573"(histone acetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0071169"(establishment of protein localization to chromatin)|interpro:IPR010750(Protein of unknown function DUF1325)|interpro:IPR037802|mint:Q96ES7|rcsb pdb:3LX7|rcsb pdb:3ME9|refseq:NP_612423.1|rcsb pdb:3MEA|rcsb pdb:3MET|rcsb pdb:3MEU|rcsb pdb:3MEV|rcsb pdb:3MEW|rcsb pdb:5C0M|reactome:R-HSA-3214847 refseq:NP_006464.1|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0030914"|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046695"("SLIK (SAGA-like) complex")|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904672"(regulation of somatic stem cell population maintenance)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|interpro:IPR009072(Histone-fold)|interpro:IPR011442(Protein of unknown function DUF1546)|interpro:IPR037796|mint:Q9Y6J9|reactome:R-HSA-3214847|ensembl:ENSG00000162227(gene)|ensembl:ENST00000294168(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000124"(SAGA complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated) - - comment:"author score: 117" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:4uvy31cdeHtlQ4BHWSOLE8Szkq49606 rogid:ZcrK24blWTsAkCgruDbSiUflbtA9606 rigid:T+c0oKMaoCV2LP3oubnKMWmtD4s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96ES7 uniprotkb:O75529 intact:EBI-743117|ensembl:ENSP00000316114|uniprotkb:Q96MF5 intact:EBI-1785876|uniprotkb:Q8IW31|uniprotkb:Q5TDI6|uniprotkb:Q5TDI5|ensembl:ENSP00000258281 psi-mi:sgf29_human(display_long)|uniprotkb:SGF29(gene name)|psi-mi:SGF29(display_short)|uniprotkb:CCDC101(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 101(gene name synonym)|uniprotkb:SAGA complex-associated factor 29(gene name synonym) psi-mi:taf5l_human(display_long)|uniprotkb:TAF5L(gene name)|psi-mi:TAF5L(display_short)|uniprotkb:PAF65B(gene name synonym)|uniprotkb:PCAF-associated factor 65 beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477135|imex:IM-26985-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000176476(gene)|ensembl:ENST00000317058(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0016573"(histone acetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0071169"(establishment of protein localization to chromatin)|interpro:IPR010750(Protein of unknown function DUF1325)|interpro:IPR037802|mint:Q96ES7|rcsb pdb:3LX7|rcsb pdb:3ME9|refseq:NP_612423.1|rcsb pdb:3MEA|rcsb pdb:3MET|rcsb pdb:3MEU|rcsb pdb:3MEV|rcsb pdb:3MEW|rcsb pdb:5C0M|reactome:R-HSA-3214847 refseq:NP_001020418.1|refseq:NP_055224.1|refseq:XP_005273156.1|dip:DIP-28147N|ensembl:ENSG00000135801(gene)|ensembl:ENST00000258281(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016607"(nuclear speck)|go:"GO:0030914"|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:1904672"(regulation of somatic stem cell population maintenance)|interpro:IPR001680(WD40 repeat)|interpro:IPR007582(WD40 associated region in TFIID subunit)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037264|interpro:IPR037783|interpro:IPR037826|mint:O75529|reactome:R-HSA-3214847 - - comment:"author score: 117" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:4uvy31cdeHtlQ4BHWSOLE8Szkq49606 rogid:3D2y64CWMvwok3BvV2CpH6iX84E9606 rigid:T+c0oKMaoCV2LP3oubnKMWmtD4s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96ES7 uniprotkb:O75528 intact:EBI-743117|ensembl:ENSP00000316114|uniprotkb:Q96MF5 intact:EBI-473249|uniprotkb:Q9UFS2|intact:EBI-28973289|ensembl:ENSP00000307684|ensembl:ENSP00000393471|uniprotkb:Q6FI83 psi-mi:sgf29_human(display_long)|uniprotkb:SGF29(gene name)|psi-mi:SGF29(display_short)|uniprotkb:CCDC101(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 101(gene name synonym)|uniprotkb:SAGA complex-associated factor 29(gene name synonym) psi-mi:tada3_human(display_long)|uniprotkb:ADA3 homolog(gene name synonym)|uniprotkb:STAF54(gene name synonym)|uniprotkb:TADA3(gene name)|psi-mi:TADA3(display_short)|uniprotkb:ADA3(gene name synonym)|uniprotkb:TADA3L(gene name synonym)|uniprotkb:Transcriptional adapter 3-like(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477135|imex:IM-26985-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000176476(gene)|ensembl:ENST00000317058(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0016573"(histone acetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070461"(SAGA-type complex)|go:"GO:0071169"(establishment of protein localization to chromatin)|interpro:IPR010750(Protein of unknown function DUF1325)|interpro:IPR037802|mint:Q96ES7|rcsb pdb:3LX7|rcsb pdb:3ME9|refseq:NP_612423.1|rcsb pdb:3MEA|rcsb pdb:3MET|rcsb pdb:3MEU|rcsb pdb:3MEV|rcsb pdb:3MEW|rcsb pdb:5C0M|reactome:R-HSA-3214847 ensembl:ENSG00000171148(gene)|ensembl:ENST00000301964(transcript)|ensembl:ENST00000440161(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030914"|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR019340|mint:O75528|reactome:R-HSA-3214847|reactome:R-HSA-5689880|ensembl:ENSP00000307684|ensembl:ENST00000343450|ensembl:ENSP00000343649|ensembl:ENSP00000393471|refseq:NP_006345.1|refseq:NP_597814.1|refseq:NP_001265199.1 - - comment:"author score: 146" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:4uvy31cdeHtlQ4BHWSOLE8Szkq49606 rogid:5NQkQiw+G/8uL2fjoMgW8+mTB8o9606 rigid:T+c0oKMaoCV2LP3oubnKMWmtD4s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95503 uniprotkb:P11940 intact:EBI-3951758|uniprotkb:A8KAH0|uniprotkb:Q96EM5|intact:EBI-28986885|ensembl:ENSP00000384490 intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004 psi-mi:cbx6_human(display_long)|uniprotkb:CBX6(gene name)|psi-mi:CBX6(display_short) psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477036|imex:IM-26985-231 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001290423.1|ensembl:ENSG00000183741(gene)|refseq:NP_055107.3|ensembl:ENST00000407418(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:O95503|rcsb pdb:3GV6|rcsb pdb:3I90|reactome:R-HSA-2559580|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSP00000384490|dip:DIP-48605N interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:4iNHCYe1bjb/JcurXP1iGoO/2uA9606 rogid:XudTSPq2h9ckKAc48X88RVafPRU9606 rigid:ORdisuIW0fMvOgIl4YuEtqEV8L4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95503 uniprotkb:P16403 intact:EBI-3951758|uniprotkb:A8KAH0|uniprotkb:Q96EM5|intact:EBI-28986885|ensembl:ENSP00000384490 intact:EBI-358372|ensembl:ENSP00000339566|uniprotkb:A8K4I2 psi-mi:cbx6_human(display_long)|uniprotkb:CBX6(gene name)|psi-mi:CBX6(display_short) psi-mi:h12_human(display_long)|uniprotkb:H1-2(gene name)|psi-mi:H1-2(display_short)|uniprotkb:H1F2(gene name synonym)|uniprotkb:HIST1H1C(gene name synonym)|uniprotkb:Histone H1c(gene name synonym)|uniprotkb:Histone H1d(gene name synonym)|uniprotkb:Histone H1s-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477036|imex:IM-26985-231 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001290423.1|ensembl:ENSG00000183741(gene)|refseq:NP_055107.3|ensembl:ENST00000407418(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:O95503|rcsb pdb:3GV6|rcsb pdb:3I90|reactome:R-HSA-2559580|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSP00000384490|dip:DIP-48605N refseq:NP_005310.1|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P16403|reactome:R-HSA-140342|reactome:R-HSA-2559584|ensembl:ENSG00000187837(gene)|ensembl:ENST00000343677(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|dip:DIP-36359N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:4iNHCYe1bjb/JcurXP1iGoO/2uA9606 rogid:eRT5bTyBJUg6nRANMRYZekT4N+g9606 rigid:ORdisuIW0fMvOgIl4YuEtqEV8L4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95503 uniprotkb:P62424 intact:EBI-3951758|uniprotkb:A8KAH0|uniprotkb:Q96EM5|intact:EBI-28986885|ensembl:ENSP00000384490 intact:EBI-354172|uniprotkb:P11518|uniprotkb:Q5T8U4|ensembl:ENSP00000361076|ensembl:ENSP00000487443 psi-mi:cbx6_human(display_long)|uniprotkb:CBX6(gene name)|psi-mi:CBX6(display_short) psi-mi:rl7a_human(display_long)|uniprotkb:RPL7A(gene name)|psi-mi:RPL7A(display_short)|uniprotkb:SURF-3(gene name synonym)|uniprotkb:SURF3(gene name synonym)|uniprotkb:Surfeit locus protein 3(gene name synonym)|uniprotkb:PLA-X polypeptide(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477036|imex:IM-26985-231 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001290423.1|ensembl:ENSG00000183741(gene)|refseq:NP_055107.3|ensembl:ENST00000407418(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:O95503|rcsb pdb:3GV6|rcsb pdb:3I90|reactome:R-HSA-2559580|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSP00000384490|dip:DIP-48605N refseq:NP_000963.1|dip:DIP-31502N|ensembl:ENSG00000148303(gene)|ensembl:ENSG00000280858(gene)|ensembl:ENST00000323345(transcript)|ensembl:ENST00000630979(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR001921(Ribosomal protein L7A)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|mint:P62424|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|go:"GO:0005634"(nucleus)|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:4iNHCYe1bjb/JcurXP1iGoO/2uA9606 rogid:shPtLmc+oabT/rSwho+tP1iJy4k9606 rigid:ORdisuIW0fMvOgIl4YuEtqEV8L4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95503 uniprotkb:Q8IXK0 intact:EBI-3951758|uniprotkb:A8KAH0|uniprotkb:Q96EM5|intact:EBI-28986885|ensembl:ENSP00000384490 intact:EBI-713786|uniprotkb:Q8N306|uniprotkb:Q8TAG8|uniprotkb:A1L4Q1|uniprotkb:Q2TAL3|uniprotkb:Q5T0C1|uniprotkb:Q6NUJ6|uniprotkb:Q6ZQR1|uniprotkb:Q96BL4|uniprotkb:Q9Y4Y7|ensembl:ENSP00000257118|uniprotkb:D3DPR2|uniprotkb:A8KA40 psi-mi:cbx6_human(display_long)|uniprotkb:CBX6(gene name)|psi-mi:CBX6(display_short) psi-mi:phc2_human(display_long)|uniprotkb:Early development regulatory protein 2(gene name synonym)|uniprotkb:PHC2(gene name)|psi-mi:PHC2(display_short)|uniprotkb:EDR2(gene name synonym)|uniprotkb:PH2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477036|imex:IM-26985-231 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001290423.1|ensembl:ENSG00000183741(gene)|refseq:NP_055107.3|ensembl:ENST00000407418(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:O95503|rcsb pdb:3GV6|rcsb pdb:3I90|reactome:R-HSA-2559580|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSP00000384490|dip:DIP-48605N interpro:IPR038603|mint:Q8IXK0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR013761(Sterile alpha motif-type)|ensembl:ENSG00000134686(gene)|ensembl:ENST00000257118(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|refseq:NP_004418.2|refseq:NP_932157.1|refseq:XP_016856005.1|refseq:XP_016856006.1|refseq:XP_016856007.1|refseq:XP_005270627.1|dip:DIP-34464N - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:4iNHCYe1bjb/JcurXP1iGoO/2uA9606 rogid:7si/KU2tHoxviuCr70ncQERDWmY9606 rigid:ORdisuIW0fMvOgIl4YuEtqEV8L4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95503 uniprotkb:Q13185 intact:EBI-3951758|uniprotkb:A8KAH0|uniprotkb:Q96EM5|intact:EBI-28986885|ensembl:ENSP00000384490 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 psi-mi:cbx6_human(display_long)|uniprotkb:CBX6(gene name)|psi-mi:CBX6(display_short) psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477036|imex:IM-26985-231 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001290423.1|ensembl:ENSG00000183741(gene)|refseq:NP_055107.3|ensembl:ENST00000407418(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:O95503|rcsb pdb:3GV6|rcsb pdb:3I90|reactome:R-HSA-2559580|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSP00000384490|dip:DIP-48605N go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:4iNHCYe1bjb/JcurXP1iGoO/2uA9606 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rigid:ORdisuIW0fMvOgIl4YuEtqEV8L4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95503 uniprotkb:Q99496 intact:EBI-3951758|uniprotkb:A8KAH0|uniprotkb:Q96EM5|intact:EBI-28986885|ensembl:ENSP00000384490 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:cbx6_human(display_long)|uniprotkb:CBX6(gene name)|psi-mi:CBX6(display_short) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477036|imex:IM-26985-231 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001290423.1|ensembl:ENSG00000183741(gene)|refseq:NP_055107.3|ensembl:ENST00000407418(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:O95503|rcsb pdb:3GV6|rcsb pdb:3I90|reactome:R-HSA-2559580|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSP00000384490|dip:DIP-48605N refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:4iNHCYe1bjb/JcurXP1iGoO/2uA9606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rigid:ORdisuIW0fMvOgIl4YuEtqEV8L4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95503 uniprotkb:Q8NDX5 intact:EBI-3951758|uniprotkb:A8KAH0|uniprotkb:Q96EM5|intact:EBI-28986885|ensembl:ENSP00000384490 intact:EBI-1223801|uniprotkb:Q5HYF0|uniprotkb:Q6NSG2|uniprotkb:Q8NFT7|uniprotkb:Q8NFZ1|uniprotkb:Q8TBM2|uniprotkb:Q9H971|uniprotkb:Q9H9I4|uniprotkb:A2RRP9|ensembl:ENSP00000420271 psi-mi:cbx6_human(display_long)|uniprotkb:CBX6(gene name)|psi-mi:CBX6(display_short) psi-mi:phc3_human(display_long)|uniprotkb:PHC3(gene name)|psi-mi:PHC3(display_short)|uniprotkb:EDR3(gene name synonym)|uniprotkb:PH3(gene name synonym)|uniprotkb:Homolog of polyhomeotic 3(gene name synonym)|uniprotkb:Early development regulatory protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477036|imex:IM-26985-231 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001290423.1|ensembl:ENSG00000183741(gene)|refseq:NP_055107.3|ensembl:ENST00000407418(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:O95503|rcsb pdb:3GV6|rcsb pdb:3I90|reactome:R-HSA-2559580|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSP00000384490|dip:DIP-48605N refseq:NP_079223.3|refseq:NP_001295045.1|ensembl:ENSP00000420271|ensembl:ENST00000495893|ensembl:ENSP00000420294|ensembl:ENST00000497658|ensembl:ENSP00000420454|ensembl:ENSG00000173889(gene)|ensembl:ENST00000494943(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:Q8NDX5|rcsb pdb:4PZN|rcsb pdb:4PZO|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:4iNHCYe1bjb/JcurXP1iGoO/2uA9606 rogid:hB1EMs+lCv19uuJ1O7+QiVCUoo89606 rigid:ORdisuIW0fMvOgIl4YuEtqEV8L4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95503 uniprotkb:Q9Y3U8 intact:EBI-3951758|uniprotkb:A8KAH0|uniprotkb:Q96EM5|intact:EBI-28986885|ensembl:ENSP00000384490 intact:EBI-1057689|uniprotkb:Q6FIG1|uniprotkb:Q9UQF6|uniprotkb:B2R4Y1|uniprotkb:D6W634|ensembl:ENSP00000252543|ensembl:ENSP00000378081|ensembl:ENSP00000462609|ensembl:ENSP00000464342 psi-mi:cbx6_human(display_long)|uniprotkb:CBX6(gene name)|psi-mi:CBX6(display_short) psi-mi:rl36_human(display_long)|uniprotkb:RPL36(gene name)|psi-mi:RPL36(display_short)|uniprotkb:Large ribosomal subunit protein eL36(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477036|imex:IM-26985-231 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001290423.1|ensembl:ENSG00000183741(gene)|refseq:NP_055107.3|ensembl:ENST00000407418(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:O95503|rcsb pdb:3GV6|rcsb pdb:3I90|reactome:R-HSA-2559580|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSP00000384490|dip:DIP-48605N refseq:NP_056229.2|refseq:NP_378669.1|reactome:R-HSA-975957|mint:Q9Y3U8|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|interpro:IPR038097|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|rcsb pdb:6Y6X|ensembl:ENSG00000130255(gene)|ensembl:ENST00000347512(transcript)|ensembl:ENST00000394580(transcript)|ensembl:ENST00000577222(transcript)|ensembl:ENST00000579649(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR000509(Ribosomal protein L36e) - - comment:"author score: 29" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:4iNHCYe1bjb/JcurXP1iGoO/2uA9606 rogid:lRlRMF2jV/UHr4SX95SSCFIEV+s9606 rigid:ORdisuIW0fMvOgIl4YuEtqEV8L4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95503 uniprotkb:P35226 intact:EBI-3951758|uniprotkb:A8KAH0|uniprotkb:Q96EM5|intact:EBI-28986885|ensembl:ENSP00000384490 intact:EBI-2341576|uniprotkb:Q5T8Z3|uniprotkb:Q96F37|uniprotkb:Q16030|intact:EBI-28989037|ensembl:ENSP00000365851 psi-mi:cbx6_human(display_long)|uniprotkb:CBX6(gene name)|psi-mi:CBX6(display_short) psi-mi:bmi1_human(display_long)|uniprotkb:BMI1(gene name)|psi-mi:BMI1(display_short)|uniprotkb:PCGF4(gene name synonym)|uniprotkb:RNF51(gene name synonym)|uniprotkb:Polycomb group RING finger protein 4(gene name synonym)|uniprotkb:RING finger protein 51(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477036|imex:IM-26985-231 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001290423.1|ensembl:ENSG00000183741(gene)|refseq:NP_055107.3|ensembl:ENST00000407418(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:O95503|rcsb pdb:3GV6|rcsb pdb:3I90|reactome:R-HSA-2559580|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSP00000384490|dip:DIP-48605N refseq:NP_001190991.1|refseq:NP_005171.4|ensembl:ENSP00000365851|dip:DIP-41879N|ensembl:ENSG00000168283(gene)|ensembl:ENST00000376663(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006959"(humoral immune response)|go:"GO:0007379"(segment specification)|go:"GO:0007420"(brain development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35226|rcsb pdb:2H0D|rcsb pdb:2NA1|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:5FR6|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 - - comment:"author score: 30" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:4iNHCYe1bjb/JcurXP1iGoO/2uA9606 rogid:ruyez2gHfd/si8gxYUDZzZ1L4689606 rigid:ORdisuIW0fMvOgIl4YuEtqEV8L4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95503 uniprotkb:Q9HC52 intact:EBI-3951758|uniprotkb:A8KAH0|uniprotkb:Q96EM5|intact:EBI-28986885|ensembl:ENSP00000384490 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 psi-mi:cbx6_human(display_long)|uniprotkb:CBX6(gene name)|psi-mi:CBX6(display_short) psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477036|imex:IM-26985-231 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001290423.1|ensembl:ENSG00000183741(gene)|refseq:NP_055107.3|ensembl:ENST00000407418(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:O95503|rcsb pdb:3GV6|rcsb pdb:3I90|reactome:R-HSA-2559580|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSP00000384490|dip:DIP-48605N ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N - - comment:"author score: 53" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:4iNHCYe1bjb/JcurXP1iGoO/2uA9606 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 rigid:ORdisuIW0fMvOgIl4YuEtqEV8L4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:Q8WXF1 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-1392258|uniprotkb:Q5JTQ3|uniprotkb:Q8NCZ9|uniprotkb:Q8WXE8|uniprotkb:Q9NV36|ensembl:ENSP00000343966|ensembl:ENSP00000481916 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:pspc1_human(display_long)|uniprotkb:PSPC1(gene name)|psi-mi:PSPC1(display_short)|uniprotkb:PSP1(gene name synonym)|uniprotkb:Paraspeckle protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N refseq:XP_006719907.1|refseq:NP_001035879.1|dip:DIP-39028N|refseq:XP_016876139.1|ensembl:ENSG00000121390(gene)|ensembl:ENST00000338910(transcript)|ensembl:ENST00000619300(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034522|interpro:IPR034523|interpro:IPR035979|mint:Q8WXF1|rcsb pdb:3SDE|rcsb pdb:5IFN|rcsb pdb:5WPA - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:voQ5zJMl7FYato9iDkUYfzZ3q/k9606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:Q9NV06 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-7402939|uniprotkb:Q3MII9|uniprotkb:Q96JY7|uniprotkb:Q9NZX3|intact:MINT-4994304|uniprotkb:Q8NCH8|uniprotkb:Q8TC51|ensembl:ENSP00000484962 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:dca13_human(display_long)|uniprotkb:HSPC064(orf name)|uniprotkb:DCAF13(gene name)|psi-mi:DCAF13(display_short)|uniprotkb:WDSOF1(gene name synonym)|uniprotkb:WD repeat and SOF domain-containing protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N refseq:NP_056235.4|ensembl:ENSG00000164934(gene)|ensembl:ENST00000612750(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030054"(cell junction)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR007287(Sof1-like protein)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:Q9NV06|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-8951664 - - comment:mint|comment:homomint|function:Possible role in ribosomal RNA processing|comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:Ep2z6/V6/US0sXDqjqjpVqmf/zM9606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:Q9HC62 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-714881|uniprotkb:Q8IW97|uniprotkb:Q96SR2|uniprotkb:Q9P2L5|uniprotkb:B4DQ42|intact:EBI-10966410|ensembl:ENSP00000296257 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:senp2_human(display_long)|uniprotkb:Sentrin/SUMO-specific protease SENP2(gene name synonym)|uniprotkb:SMT3-specific isopeptidase 2(gene name synonym)|uniprotkb:Axam2(gene name synonym)|uniprotkb:SENP2(gene name)|psi-mi:SENP2(display_short)|uniprotkb:KIAA1331(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N refseq:NP_067640.2|ensembl:ENSG00000163904(gene)|ensembl:ENST00000296257(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016926"(protein desumoylation)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031648"(protein destabilization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0051028"(mRNA transport)|go:"GO:0070139"(SUMO-specific endopeptidase activity)|interpro:IPR003653(Peptidase C48, SUMO/Sentrin/Ubl1)|interpro:IPR038765|mint:Q9HC62|rcsb pdb:1TGZ|rcsb pdb:1TH0|rcsb pdb:2IO0|rcsb pdb:2IO2|rcsb pdb:2IO3|rcsb pdb:3ZO5|rcsb pdb:5AEK|reactome:R-HSA-3065679|rcsb pdb:2IO1|dip:DIP-29254N - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:zYThN+7SovDIV6Ly58vwds2CRZ49606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:P49674 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-749343|ensembl:ENSP00000352929|ensembl:ENSP00000380044|ensembl:ENSP00000384074 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:kc1e_human(display_long)|uniprotkb:CSNK1E(gene name)|psi-mi:CSNK1E(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N refseq:NP_001885.1|refseq:NP_689407.1|refseq:NP_001276841.1|dip:DIP-38050N|ensembl:ENSG00000213923(gene)|ensembl:ENST00000359867(transcript)|ensembl:ENST00000396832(transcript)|ensembl:ENST00000403904(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903827"|go:"GO:0005829"(cytosol)|go:"GO:1905426"(positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation)|go:"GO:2000052"(positive regulation of non-canonical Wnt signaling pathway)|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-400253|interpro:IPR008271(Serine/threonine protein kinase, active site)|reactome:R-HSA-5620912|reactome:R-HSA-6791226|reactome:R-HSA-8854518|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P49674|rcsb pdb:4HNI|rcsb pdb:4HOK|reactome:R-HSA-201688|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:evdzz03ba4MFWavN9xRae/Wxwio9606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:Q9P2I0 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-1043224|uniprotkb:Q6NSJ1|uniprotkb:Q9H3W7|ensembl:ENSP00000298875|uniprotkb:B3KME1 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:cpsf2_human(display_long)|uniprotkb:Cleavage and polyadenylation specificity factor 100 kDa subunit(gene name synonym)|uniprotkb:CPSF2(gene name)|psi-mi:CPSF2(display_short)|uniprotkb:CPSF100(gene name synonym)|uniprotkb:KIAA1367(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|interpro:IPR022712|interpro:IPR025069|interpro:IPR027075|interpro:IPR035639|interpro:IPR036866|mint:Q9P2I0|rcsb pdb:6URG|rcsb pdb:6V4X|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|ensembl:ENSG00000165934(gene)|ensembl:ENST00000298875(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|go:"GO:0016020"(membrane)|refseq:NP_059133.1|refseq:NP_001309201.1|dip:DIP-42500N - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:RYiaQ8q9VM7htGre4S8PkSQaCz89606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:Q9NWH9 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-2814558|uniprotkb:A8K5V8|uniprotkb:Q6ZNF2|uniprotkb:B2RTX3|uniprotkb:Q9H7C3|uniprotkb:Q658J7|uniprotkb:Q52MB3|uniprotkb:Q9H8U9|uniprotkb:Q86TK6|uniprotkb:Q2VPK7|ensembl:ENSP00000369887 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:sltm_human(display_long)|uniprotkb:SLTM(gene name)|psi-mi:SLTM(display_short)|uniprotkb:MET(gene name synonym)|uniprotkb:Modulator of estrogen-induced transcription(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N refseq:XP_006720753.1|refseq:NP_079031.2|refseq:NP_001013865.1|refseq:XP_016878069.1|ensembl:ENSG00000137776(gene)|ensembl:ENST00000380516(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0016604"(nuclear body)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0050684"(regulation of mRNA processing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034780|interpro:IPR035979|interpro:IPR036361|mint:Q9NWH9 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:/B0FdPpFi/TvMq9aGjuLOQ3zIuo9606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:Q99575 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-366741|uniprotkb:Q15037|uniprotkb:A8K5W9|intact:EBI-2560204|ensembl:ENSP00000339529|ensembl:ENSP00000385787 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:pop1_human(display_long)|uniprotkb:POP1(gene name)|psi-mi:POP1(display_short)|uniprotkb:KIAA0061(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N refseq:NP_001139332.1|refseq:NP_001139333.1|refseq:NP_055844.2|ensembl:ENSG00000104356(gene)|ensembl:ENST00000349693(transcript)|ensembl:ENST00000401707(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008033"(tRNA processing)|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR009723(Ribonuclease P/MRP, POP1)|interpro:IPR012590(POPLD)|interpro:IPR039182|mint:Q99575|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:XJxSr17TfVuetXKgpQPjs2QKMV49606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:Q8TAD8 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-749336|uniprotkb:Q96SP9|uniprotkb:Q9H9T7|intact:EBI-1046254|ensembl:ENSP00000296215 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:snip1_human(display_long)|uniprotkb:SNIP1(gene name)|psi-mi:SNIP1(display_short)|uniprotkb:FHA domain-containing protein SNIP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N refseq:NP_078976.2|ensembl:ENSG00000163877(gene)|ensembl:ENST00000296215(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-38956N|mint:Q8TAD8|rcsb pdb:5Z56|rcsb pdb:5Z57|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|rcsb pdb:5Z58|rcsb pdb:6FF7|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0071005"(U2-type precatalytic spliceosome)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain) - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:2UWnTY01RhPuUx3PepGug23l11U9606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:Q8NCA5 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-1210765|uniprotkb:B2RNA2|uniprotkb:Q9Y3Y6|intact:EBI-10970131|ensembl:ENSP00000238823 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:fa98a_human(display_long)|uniprotkb:FAM98A(gene name)|psi-mi:FAM98A(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N refseq:NP_056290.3|go:"GO:0032418"(lysosome localization)|go:"GO:0072669"(tRNA-splicing ligase complex)|go:"GO:1900029"(positive regulation of ruffle assembly)|interpro:IPR018797|mint:Q8NCA5|ensembl:ENSG00000119812(gene)|ensembl:ENST00000238823(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0006479"(protein methylation)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression) - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:MEsSX6iNk+0s/sLuUawu0GR9bW89606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:P55081 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-1048159|uniprotkb:Q86TG6|ensembl:ENSP00000267812 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:mfap1_human(display_long)|uniprotkb:Spliceosome B complex protein MFAP1(gene name synonym)|uniprotkb:MFAP1(gene name)|psi-mi:MFAP1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N refseq:NP_005917.2|ensembl:ENSG00000140259(gene)|ensembl:ENST00000267812(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001527"(microfibril)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0005813"(centrosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|interpro:IPR009730(Micro-fibrillar-associated 1, C-terminal)|interpro:IPR033194|mint:P55081|rcsb pdb:5F5S|rcsb pdb:5O9Z|rcsb pdb:6AHD|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|reactome:R-HSA-2129379 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:38SGUW2hc2ZwbmyTO52uGQRw79U9606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:Q16630 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-358410|uniprotkb:Q53ES1|uniprotkb:Q9BSJ7|uniprotkb:Q9BW18|intact:EBI-740029|uniprotkb:A8K7K9|ensembl:ENSP00000391774 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:cpsf6_human(display_long)|uniprotkb:CPSF6(gene name)|psi-mi:CPSF6(display_short)|uniprotkb:CFIM68(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 68 kDa subunit(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 68 kDa subunit(gene name synonym)|uniprotkb:Protein HPBRII-4/7(gene name synonym)|uniprotkb:Cleavage factor Im complex 68 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N refseq:NP_008938.2|refseq:NP_001287876.1|ensembl:ENSG00000111605(gene)|ensembl:ENST00000435070(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005737"(cytoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0035061"(interchromatin granule)|go:"GO:0042382"(paraspeckles)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:1990448"(exon-exon junction complex binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034769|interpro:IPR034772|interpro:IPR035979|mint:Q16630|rcsb pdb:3P5T|rcsb pdb:3P6Y|rcsb pdb:3Q2S|rcsb pdb:3Q2T|rcsb pdb:4B4N|rcsb pdb:4U0A|rcsb pdb:4U0B|rcsb pdb:4WYM|rcsb pdb:6AY9|rcsb pdb:6GX9|reactome:R-HSA-1839117|reactome:R-HSA-5655302|dip:DIP-34501N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:nvZBuI+X/m+5MGIsfh2ToVe5nFs9606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:O43172 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-718395|uniprotkb:O43445|uniprotkb:O43864|uniprotkb:Q96DG2|uniprotkb:Q96IK4|uniprotkb:Q5T1M8|ensembl:ENSP00000363315 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:prp4_human(display_long)|uniprotkb:U4/U6 snRNP 60 kDa protein(gene name synonym)|uniprotkb:WD splicing factor Prp4(gene name synonym)|uniprotkb:PRP4 homolog(gene name synonym)|uniprotkb:PRPF4(gene name)|psi-mi:PRPF4(display_short)|uniprotkb:PRP4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N refseq:NP_004688.2|refseq:NP_001231855.1|ensembl:ENSG00000136875(gene)|ensembl:ENST00000374199(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071001"(U4/U6 snRNP)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0097525"(spliceosomal snRNP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR014906("Pre-mRNA processing factor 4 (PRP4) like")|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|interpro:IPR015943(WD40/YVTN repeat-like)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017070"(U6 snRNA binding)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036285|interpro:IPR036322|mint:O43172|rcsb pdb:1MZW|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|reactome:R-HSA-72163|go:"GO:0030621"(U4 snRNA binding) - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:PPTNuhEFj4D+gTv/ctTTMzGmFA09606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:P82912 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-2371859|uniprotkb:Q969D7|uniprotkb:Q96GI3|uniprotkb:Q9BYC3|uniprotkb:B2RD52|ensembl:ENSP00000317376 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:rt11_human(display_long)|uniprotkb:MRPS11(gene name)|psi-mi:MRPS11(display_short)|uniprotkb:RPMS11(gene name synonym)|uniprotkb:Cervical cancer proto-oncogene 2 protein(gene name synonym)|uniprotkb:HCC2(orf name)|uniprotkb:Mitochondrial small ribosomal subunit protein uS11m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N refseq:NP_001308899.1|refseq:NP_001308901.1|refseq:NP_001308902.1|refseq:NP_001308903.1|refseq:NP_001308905.1|refseq:NP_073750.2|refseq:NP_789775.1|ensembl:ENSG00000181991(gene)|ensembl:ENST00000325844(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR001971(Ribosomal protein S11)|interpro:IPR018102|interpro:IPR036967|mint:P82912|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:aw3XzNBYY0igd4AUE1OQyfFn8pk9606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:Q15427 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-348469|ensembl:ENSP00000271628|intact:EBI-1047735|uniprotkb:Q5SZ63 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:sf3b4_human(display_long)|uniprotkb:SF3B4(gene name)|psi-mi:SF3B4(display_short)|uniprotkb:SAP49(gene name synonym)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 49 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N refseq:NP_005841.1|ensembl:ENSG00000143368(gene)|ensembl:ENST00000271628(transcript)|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|rcsb pdb:6AHD|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034158|go:"GO:0000375"(RNA splicing, via transesterification reactions)|interpro:IPR034159|interpro:IPR035979|mint:Q15427|rcsb pdb:1X5T|rcsb pdb:5GVQ|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:Jgy6WmBFKkphpZLLte2GgsagUVI9606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:Q9BSH4 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-747797|uniprotkb:Q8N3N6|uniprotkb:Q9UI60|uniprotkb:B2RD21|ensembl:ENSP00000258975 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:taco1_human(display_long)|uniprotkb:PRO0477(orf name)|uniprotkb:TACO1(gene name)|psi-mi:TACO1(display_short)|uniprotkb:CCDC44(gene name synonym)|uniprotkb:Translational activator of mitochondrially-encoded cytochrome c oxidase I(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 44(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N refseq:NP_057444.2|ensembl:ENSG00000136463(gene)|ensembl:ENST00000258975(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0019843"(rRNA binding)|go:"GO:0033617"(mitochondrial cytochrome c oxidase assembly)|go:"GO:0061743"(motor learning)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:0097177"(mitochondrial ribosome binding)|go:"GO:1904959"(regulation of cytochrome-c oxidase activity)|interpro:IPR002876(Protein of unknown function DUF28)|interpro:IPR017856(Integrase, N-terminal zinc-binding domain-like)|interpro:IPR026564|interpro:IPR029072|mint:Q9BSH4|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:c/tu89NvCs3Kt8qO8e5F6hrywBo9606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:O43809 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-355720|uniprotkb:Q6IB85|uniprotkb:Q6NE84|ensembl:ENSP00000300291 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:cpsf5_human(display_long)|uniprotkb:NUDT21(gene name)|psi-mi:NUDT21(display_short)|uniprotkb:CFIM25(gene name synonym)|uniprotkb:CPSF25(gene name synonym)|uniprotkb:CPSF5(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 25 kDa subunit(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 21(gene name synonym)|uniprotkb:Cleavage factor Im complex 25 kDa subunit(gene name synonym)|uniprotkb:Nudix hydrolase 21(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 68 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N refseq:NP_008937.1|ensembl:ENSG00000167005(gene)|ensembl:ENST00000300291(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006397"(mRNA processing)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0031439"(positive regulation of mRNA cleavage)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042382"(paraspeckles)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|go:"GO:1900365"(positive regulation of mRNA polyadenylation)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:2000738"(positive regulation of stem cell differentiation)|go:"GO:2000975"(positive regulation of pro-B cell differentiation)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR016706(Cleavage and polyadenylation specificity factor, 25 kDa subunit)|mint:O43809|rcsb pdb:2CL3|rcsb pdb:2J8Q|rcsb pdb:3BAP|rcsb pdb:3BHO|rcsb pdb:3MDG|rcsb pdb:3MDI|rcsb pdb:3N9U|rcsb pdb:3P5T|rcsb pdb:3P6Y|rcsb pdb:3Q2S|rcsb pdb:3Q2T|rcsb pdb:5R4P|rcsb pdb:5R4Q|rcsb pdb:5R4R|rcsb pdb:5R4S|rcsb pdb:5R4T|rcsb pdb:5R4U|rcsb pdb:5R64|rcsb pdb:5R65|rcsb pdb:5R66|rcsb pdb:5R67|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|dip:DIP-42502N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:Acad4mYVuS+Eox+X2CH8PYUkGAA9606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:P51608 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-1189067|uniprotkb:O15233|uniprotkb:Q6QHH9|uniprotkb:Q7Z384|ensembl:ENSP00000301948 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:mecp2_human(display_long)|uniprotkb:MECP2(gene name)|psi-mi:MECP2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N refseq:NP_001104262.1|refseq:NP_004983.1|refseq:NP_001303266.1|ensembl:ENSG00000169057(gene)|ensembl:ENST00000303391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0001662"(behavioral fear response)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001964"(startle response)|go:"GO:0001976"(nervous system process involved in regulation of systemic arterial blood pressure)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006020"(inositol metabolic process)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006576"(cellular biogenic amine metabolic process)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007416"(synapse assembly)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0007616"(long-term memory)|go:"GO:0008104"(protein localization)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016358"(dendrite development)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016571"(histone methylation)|go:"GO:0016573"(histone acetylation)|go:"GO:0019230"(proprioception)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021591"(ventricular system development)|go:"GO:0032048"(cardiolipin metabolic process)|go:"GO:0035176"(social behavior)|go:"GO:0035197"(siRNA binding)|go:"GO:0042551"(neuron maturation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051151"(negative regulation of smooth muscle cell differentiation)|go:"GO:0051707"(response to other organism)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0098794"(postsynapse)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|go:"GO:1905643"(positive regulation of DNA methylation)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000820"(negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR017353(Methyl-CpG binding protein MeCP2)|mint:P51608|rcsb pdb:1QK9|rcsb pdb:3C2I|rcsb pdb:5BT2|rcsb pdb:6C1Y|rcsb pdb:6OGJ|rcsb pdb:6OGK|reactome:R-HSA-8986944|reactome:R-HSA-9022534|reactome:R-HSA-9022535|reactome:R-HSA-9022537|reactome:R-HSA-9022538|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9022702|reactome:R-HSA-9022707|reactome:R-HSA-9022927|dip:DIP-39983N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:7c5ZZAZsqV7AciGN4hzFNWJLeUk9606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:O43491 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-1052044|uniprotkb:Q5T4F0|uniprotkb:B4DHI8|uniprotkb:Q68DV2|uniprotkb:E9PPD9|ensembl:ENSP00000338481|ensembl:ENSP00000357110 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:e41l2_human(display_long)|uniprotkb:Generally expressed protein 4.1(gene name synonym)|uniprotkb:EPB41L2(gene name)|psi-mi:EPB41L2(display_short)|uniprotkb:Erythrocyte membrane protein band 4.1-like 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N refseq:NP_001422.1|refseq:NP_001129026.1|refseq:NP_001129027.1|refseq:NP_001239589.1|refseq:XP_011533832.1|refseq:XP_011533836.1|ensembl:ENSG00000079819(gene)|ensembl:ENST00000337057(transcript)|ensembl:ENST00000368128(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007049"(cell cycle)|go:"GO:0008091"(spectrin)|go:"GO:0030054"(cell junction)|go:"GO:0030507"(spectrin binding)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0042731"(PH domain binding)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR007477(SAB)|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR030546|interpro:IPR035963|mint:O43491|reactome:R-HSA-6794361|refseq:XP_016865844.1|refseq:XP_016865848.1|refseq:XP_016865849.1|refseq:XP_016865850.1|refseq:XP_016865851.1|dip:DIP-17034N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:QvhY6g+bBqTBR8oHl/php27Wb7Y9606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:Q10570 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-347859|ensembl:ENSP00000478145|ensembl:ENSP00000484669|ensembl:ENSP00000495020|ensembl:ENSP00000495102|uniprotkb:Q96AF0 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:cpsf1_human(display_long)|uniprotkb:CPSF1(gene name)|psi-mi:CPSF1(display_short)|uniprotkb:CPSF160(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 160 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N rcsb pdb:6F9N|rcsb pdb:6FBS|rcsb pdb:6FUW|rcsb pdb:6URG|rcsb pdb:6URO|reactome:R-HSA-159231|reactome:R-HSA-6784531|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:6DNH|reactome:R-HSA-77595|ensembl:ENSG00000071894(gene)|ensembl:ENSG00000285049(gene)|ensembl:ENST00000616140(transcript)|ensembl:ENST00000620219(transcript)|ensembl:ENST00000643746(transcript)|ensembl:ENST00000644539(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|mint:Q10570|rcsb pdb:6BLY|rcsb pdb:6BM0|refseq:NP_037423.2|dip:DIP-32694N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:YZdY/qkUWUDbe+Dw3g9bY9DFbig9606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:P63241 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-373150|uniprotkb:P10159|uniprotkb:Q16182|uniprotkb:Q7L7L3|uniprotkb:Q7Z4L1|uniprotkb:Q9D0G2|uniprotkb:A8K9A0|uniprotkb:D3DTP2|ensembl:ENSP00000336776|ensembl:ENSP00000390677|ensembl:ENSP00000396073|ensembl:ENSP00000458269|ensembl:ENSP00000459196|ensembl:ENSP00000459611|ensembl:ENSP00000499855|ensembl:ENSP00000499995|ensembl:ENSP00000500414|ensembl:ENSP00000500624|ensembl:ENSP00000500717|ensembl:ENSP00000500847 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:if5a1_human(display_long)|uniprotkb:EIF5A(gene name)|psi-mi:EIF5A(display_short)|uniprotkb:Eukaryotic initiation factor 5A isoform 1(gene name synonym)|uniprotkb:eIF-4D(gene name synonym)|uniprotkb:Rev-binding factor(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N refseq:NP_001137232.1|refseq:NP_001137233.1|refseq:NP_001137234.1|refseq:NP_001961.1|refseq:XP_005256566.1|ensembl:ENSG00000132507(gene)|ensembl:ENSG00000288145(gene)|ensembl:ENST00000336458(transcript)|ensembl:ENST00000416016(transcript)|ensembl:ENST00000419711(transcript)|ensembl:ENST00000571955(transcript)|ensembl:ENST00000573542(transcript)|ensembl:ENST00000576930(transcript)|ensembl:ENST00000672250(transcript)|ensembl:ENST00000672755(transcript)|ensembl:ENST00000673099(transcript)|ensembl:ENST00000673210(transcript)|ensembl:ENST00000673259(transcript)|ensembl:ENST00000673304(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043022"(ribosome binding)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0045905"(positive regulation of translational termination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0098586"(cellular response to virus)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|interpro:IPR001884("Eukaryotic initiation factor 5A hypusine (eIF-5A)")|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR019769|interpro:IPR020189|mint:P63241|rcsb pdb:1FH4|rcsb pdb:3CPF|rcsb pdb:5DLQ|reactome:R-HSA-204626 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:/smk81DLs+XvrqXmIZpfvdHHauk9606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:Q9NY93 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-372376|uniprotkb:Q9H9I8|intact:EBI-1051948|uniprotkb:Q6IAE2|uniprotkb:A4D2K9|ensembl:ENSP00000258772|uniprotkb:C9JV95 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:ddx56_human(display_long)|uniprotkb:DDX56(gene name)|psi-mi:DDX56(display_short)|uniprotkb:DDX21(gene name synonym)|uniprotkb:DEAD box protein 56(gene name synonym)|uniprotkb:ATP-dependent 61 kDa nucleolar RNA helicase(gene name synonym)|uniprotkb:DEAD box protein 21(gene name synonym)|uniprotkb:NOH61(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N refseq:NP_061955.1|ensembl:ENSG00000136271(gene)|ensembl:ENST00000258772(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q9NY93|refseq:NP_001244118.1 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:Pfa1hEJ7HnBZtSO4aZ2xRixpldc9606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:P30533 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-715927|uniprotkb:Q2M310|uniprotkb:Q53HQ3|uniprotkb:Q53HS6|uniprotkb:D3DVR9|ensembl:ENSP00000497444 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:amrp_human(display_long)|uniprotkb:Low density lipoprotein receptor-related protein-associated protein 1(gene name synonym)|uniprotkb:LRPAP1(gene name)|psi-mi:LRPAP1(display_short)|uniprotkb:A2MRAP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N refseq:NP_002328.1|ensembl:ENSG00000163956(gene)|ensembl:ENST00000650182(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008201"(heparin binding)|go:"GO:0009986"(cell surface)|go:"GO:0010916"(negative regulation of very-low-density lipoprotein particle clearance)|go:"GO:0012505"(endomembrane system)|go:"GO:0031904"(endosome lumen)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0035473"(lipase binding)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0048237"(rough endoplasmic reticulum lumen)|go:"GO:0048259"(regulation of receptor-mediated endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070326"(very-low-density lipoprotein particle receptor binding)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1900116"(extracellular negative regulation of signal transduction)|go:"GO:1900222"(negative regulation of amyloid-beta clearance)|go:"GO:1900223"(positive regulation of amyloid-beta clearance)|interpro:IPR009066(Alpha-2-macroglobulin receptor-associated protein, domain 1)|interpro:IPR010483(Alpha-2-macroglobulin RAP, C-terminal)|interpro:IPR036744|interpro:IPR037999|interpro:IPR038001|interpro:IPR038003|mint:P30533|rcsb pdb:1LRE|rcsb pdb:1NRE|rcsb pdb:1OP1|rcsb pdb:1OV2|rcsb pdb:2FCW|rcsb pdb:2FTU|rcsb pdb:2FYL|rcsb pdb:2P01|rcsb pdb:2P03|dip:DIP-39355N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:TIbL+P1GW4op4Qawa4lpg8iXUaQ9606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:P39019 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-354451|ensembl:ENSP00000469228|ensembl:ENSP00000470004|ensembl:ENSP00000470972 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:rs19_human(display_long)|uniprotkb:RPS19(gene name)|psi-mi:RPS19(display_short)|uniprotkb:Small ribosomal subunit protein eS19(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N refseq:NP_001013.1|ensembl:ENSG00000105372(gene)|ensembl:ENST00000593863(transcript)|ensembl:ENST00000598742(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003723"(RNA binding)|ensembl:ENST00000600467(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0007000"(nucleolus organization)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0060265"(positive regulation of respiratory burst involved in inflammatory response)|go:"GO:0060266"(negative regulation of respiratory burst involved in inflammatory response)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001266(Ribosomal protein S19e)|interpro:IPR018277|interpro:IPR036388|interpro:IPR036390|mint:P39019|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001308412.1|refseq:NP_001308413.1 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:3YqdJJJG+2nqoBf3PLu1fs7pVkY9606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:O43290 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-607761|ensembl:ENSP00000310448|uniprotkb:A6NDN1|uniprotkb:Q53GB5 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:snut1_human(display_long)|uniprotkb:U4/U6.U5 tri-snRNP-associated 110 kDa protein(gene name synonym)|uniprotkb:SART1(gene name)|psi-mi:SART1(display_short)|uniprotkb:SNU66 homolog(gene name synonym)|uniprotkb:Squamous cell carcinoma antigen recognized by T-cells 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N ensembl:ENSG00000175467(gene)|ensembl:ENST00000312397(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000481"(maturation of 5S rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0045585"(positive regulation of cytotoxic T cell differentiation)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR005011(SART-1 protein)|mint:O43290|rcsb pdb:4PYU|rcsb pdb:5O9Z|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|reactome:R-HSA-72163|refseq:NP_005137.1|dip:DIP-33360N - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:egvWHy7UXW+MkGtGEW984yvRU9k9606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:P48426 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-3924422|uniprotkb:Q5VUX3|uniprotkb:D3DRV1|uniprotkb:B0YJ66|uniprotkb:P53807|ensembl:ENSP00000365757|uniprotkb:B4DGX2 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:pi42a_human(display_long)|uniprotkb:PIP4K2A(gene name)|psi-mi:PIP4K2A(display_short)|uniprotkb:PIP5K2(gene name synonym)|uniprotkb:PIP5K2A(gene name synonym)|uniprotkb:Diphosphoinositide kinase 2-alpha(gene name synonym)|uniprotkb:PIP5KIII(gene name synonym)|uniprotkb:"PtdIns(4)P-5-kinase B isoform"(gene name synonym)|uniprotkb:"PtdIns(4)P-5-kinase C isoform"(gene name synonym)|uniprotkb:"PtdIns(5)P-4-kinase isoform 2-alpha"(gene name synonym)|uniprotkb:1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha(gene name synonym)|uniprotkb:Phosphatidylinositol 5-phosphate 4-kinase type II alpha(gene name synonym)|uniprotkb:PI5P4KA(gene name synonym)|uniprotkb:Phosphatidylinositol 5-Phosphate 4-Kinase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N refseq:NP_005019.2|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016308"(1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:0016309"(1-phosphatidylinositol-5-phosphate 4-kinase activity)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0061909"(autophagosome-lysosome fusion)|go:"GO:0090119"(vesicle-mediated cholesterol transport)|go:"GO:0090217"(negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity)|ensembl:ENST00000376573(transcript)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR002498(Phosphatidylinositol-4-phosphate 5-kinase, core)|interpro:IPR023610|interpro:IPR027484|mint:P48426|rcsb pdb:2YBX|rcsb pdb:6OSP|rcsb pdb:6UX9|rcsb pdb:6YM3|rcsb pdb:6YM4|rcsb pdb:6YM5|rcsb pdb:7N6Z|rcsb pdb:7N7J|rcsb pdb:7N7K|rcsb pdb:7N7L|rcsb pdb:7N7M|rcsb pdb:7N7N|rcsb pdb:7N7O|reactome:R-HSA-1660499|reactome:R-HSA-6811555|reactome:R-HSA-6811558|reactome:R-HSA-8847453|go:"GO:1902635"(1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process)|ensembl:ENSG00000150867(gene)|refseq:NP_001316991.1|refseq:XP_016871819.1|refseq:XP_016871820.1 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:Fmsp/H2ucCjs7wyiCgEqe9Y5UT49606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:P08865 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-354112|uniprotkb:Q6NSD1|uniprotkb:Q6NXQ8|uniprotkb:Q86VC0|uniprotkb:P11085|uniprotkb:P12030|uniprotkb:Q16471|uniprotkb:Q6IPD1|uniprotkb:Q6IPD2|ensembl:ENSP00000346067 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:rssa_human(display_long)|uniprotkb:RPSA(gene name)|psi-mi:RPSA(display_short)|uniprotkb:LAMBR(gene name synonym)|uniprotkb:LAMR1(gene name synonym)|uniprotkb:Laminin receptor 1(gene name synonym)|uniprotkb:37/67 kDa laminin receptor(gene name synonym)|uniprotkb:Laminin-binding protein precursor p40(gene name synonym)|uniprotkb:Colon carcinoma laminin-binding protein(gene name synonym)|uniprotkb:NEM/1CHD4(gene name synonym)|uniprotkb:Multidrug resistance-associated protein MGr1-Ag(gene name synonym)|uniprotkb:37 kDa laminin receptor precursor(gene name synonym)|uniprotkb:67 kDa laminin receptor(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N refseq:NP_002286.2|refseq:NP_001291217.1|dip:DIP-32878N|ensembl:ENSG00000168028(gene)|ensembl:ENST00000301821(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005055"(laminin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0007155"(cell adhesion)|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6ZOJ|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043022"(ribosome binding)|go:"GO:0043236"(laminin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005707(Ribosomal protein S2, eukaryotic/archaeal)|interpro:IPR018130|interpro:IPR023591|interpro:IPR027498|interpro:IPR027504|interpro:IPR032281|mint:P08865|rcsb pdb:3BCH|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:Jpv3I3G5C297fHfNwIqyB9Pf8/A9606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:Q8WWM7 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-948363|ensembl:ENSP00000338718|uniprotkb:O95135|uniprotkb:Q6NVJ8|uniprotkb:Q6PJW6|uniprotkb:Q8IU61|uniprotkb:Q8IU95|uniprotkb:Q8WWM3|uniprotkb:Q8WWM4|uniprotkb:Q8WWM5|uniprotkb:Q8WWM6|uniprotkb:Q99703|uniprotkb:B9EGM2|uniprotkb:E9PAR9|uniprotkb:A8K1R6|uniprotkb:Q63ZY4 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:atx2l_human(display_long)|uniprotkb:Ataxin-2 domain protein(gene name synonym)|uniprotkb:Ataxin-2-related protein(gene name synonym)|uniprotkb:ATXN2L(gene name)|psi-mi:ATXN2L(display_short)|uniprotkb:A2D(gene name synonym)|uniprotkb:A2LG(gene name synonym)|uniprotkb:A2LP(gene name synonym)|uniprotkb:A2RP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N ensembl:ENSG00000168488(gene)|ensembl:ENST00000336783(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045296"(cadherin binding)|interpro:IPR009604(Ataxin-2, N-terminal)|interpro:IPR009818(Ataxin-2, C-terminal)|interpro:IPR025852|mint:Q8WWM7|refseq:NP_009176.2|refseq:NP_663760.1|refseq:NP_680780.1|refseq:NP_680781.1|refseq:XP_005255123.1|refseq:NP_059867.3|refseq:NP_680782.1 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:t7lrS10IM/5pt+rrbqBRowZ6b+09606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:P49756 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-2211856|uniprotkb:Q9UEQ5|uniprotkb:Q9UIE9|uniprotkb:A0PJL9|uniprotkb:B2RNA8|uniprotkb:B3KT03|uniprotkb:Q2TA72|uniprotkb:Q5XJ17|uniprotkb:Q6P665|uniprotkb:Q9H6A1|intact:EBI-2839256|intact:EBI-2859423|ensembl:ENSP00000261973|ensembl:ENSP00000431150 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:rbm25_human(display_long)|uniprotkb:RBM25(gene name)|psi-mi:RBM25(display_short)|uniprotkb:RNPC7(gene name synonym)|uniprotkb:RNA-binding motif protein 25(gene name synonym)|uniprotkb:RNA-binding region-containing protein 7(gene name synonym)|uniprotkb:Protein S164(gene name synonym)|uniprotkb:Arg/Glu/Asp-rich protein of 120 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N refseq:XP_011535346.1|refseq:NP_067062.1|refseq:XP_011535347.1|ensembl:ENSG00000119707(gene)|ensembl:ENST00000261973(transcript)|ensembl:ENST00000527432(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002483(Splicing factor PWI)|interpro:IPR034268|interpro:IPR035979|interpro:IPR036483|mint:P49756|rcsb pdb:3V53|interpro:IPR012677(Nucleotide-binding, alpha-beta plait) - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:VRZ6bJro7qw+BXS0rpYZoiD8iAM9606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:O75400 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-473291|uniprotkb:O43856|uniprotkb:O75404|uniprotkb:Q8TBQ1|uniprotkb:Q9H782|uniprotkb:Q9NWU9|uniprotkb:Q9P0Q2|uniprotkb:Q9Y5A8 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:pr40a_human(display_long)|uniprotkb:Formin-binding protein 3(gene name synonym)|uniprotkb:Formin-binding protein 11(gene name synonym)|uniprotkb:Huntingtin-interacting protein A(gene name synonym)|uniprotkb:Huntingtin yeast partner A(gene name synonym)|uniprotkb:Fas ligand-associated factor 1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-6(gene name synonym)|uniprotkb:HSPC225(orf name)|uniprotkb:PRPF40A(gene name)|psi-mi:PRPF40A(display_short)|uniprotkb:FLAF1(gene name synonym)|uniprotkb:HYPA(gene name synonym)|uniprotkb:FBP11(gene name synonym)|uniprotkb:FNBP3(gene name synonym)|uniprotkb:HIP10(gene name synonym)|uniprotkb:Huntingtin-interacting protein 10(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005685"(U1 snRNP)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016477"(cell migration)|go:"GO:0016607"(nuclear speck)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0051301"(cell division)|go:"GO:0071004"(U2-type prespliceosome)|rcsb pdb:1UZC|rcsb pdb:1YWI|rcsb pdb:1YWJ|rcsb pdb:1ZR7|rcsb pdb:2CQN|rcsb pdb:2DYF|rcsb pdb:2KZG|rcsb pdb:2L5F|rcsb pdb:2L9V|rcsb pdb:2LKS|reactome:R-HSA-72163|refseq:NP_060362.3|interpro:IPR002713(FF)|interpro:IPR001202(WW/Rsp5/WWP)|mint:O75400|interpro:IPR036020|interpro:IPR036517|interpro:IPR039726 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:XgnBshjHK5u08HROtUS9Zr2Ot809606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:Q9Y2P8 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-11026509|uniprotkb:Q9NY00|uniprotkb:Q5VYW9|uniprotkb:Q9P044|uniprotkb:Q9H9D0|uniprotkb:D3DRI2|uniprotkb:Q5VZU1|ensembl:ENSP00000371169 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:rcl1_human(display_long)|uniprotkb:RCL1(gene name)|psi-mi:RCL1(display_short)|uniprotkb:RNAC(gene name synonym)|uniprotkb:RPC2(gene name synonym)|uniprotkb:RPCL1(gene name synonym)|uniprotkb:RTC2(gene name synonym)|uniprotkb:HSPC338(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N refseq:NP_001273628.1|refseq:NP_001273629.1|refseq:NP_001273630.1|refseq:NP_005763.3|refseq:XP_011515975.1|ensembl:ENSG00000120158(gene)|ensembl:ENST00000381750(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000479"("endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000480"("endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|interpro:IPR000228(RNA 3'-terminal phosphate cyclase)|interpro:IPR013791(RNA 3'-terminal phosphate cyclase, subset, insert region)|interpro:IPR013792(RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)|interpro:IPR016443(RNA 3'-terminal phosphate cyclase-like, eukaryotic)|interpro:IPR020719|interpro:IPR023797|interpro:IPR036553|interpro:IPR037136|mint:Q9Y2P8|reactome:R-HSA-6790901|reactome:R-HSA-6791226|refseq:XP_016869665.1 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:8WnLDVPrx4t1eD6h+emL5waEyDY9606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:Q5HYJ3 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-751192|uniprotkb:Q6PIU3|uniprotkb:Q8TC53|uniprotkb:B2R9C2|ensembl:ENSP00000351631 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:fa76b_human(display_long)|uniprotkb:FAM76B(gene name)|psi-mi:FAM76B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N refseq:NP_653265.3|ensembl:ENSG00000077458(gene)|ensembl:ENST00000358780(transcript)|go:"GO:0016607"(nuclear speck)|interpro:IPR029661|interpro:IPR032017|mint:Q5HYJ3 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:FWmHMXjKuPdNvpa793hQ1F+Tb909606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:Q9BU76 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-742459|uniprotkb:Q6P5Y0|uniprotkb:Q6ZTZ6|uniprotkb:Q6ZWA6|uniprotkb:Q8IZH3|ensembl:ENSP00000272139 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:mmta2_human(display_long)|uniprotkb:MMTAG2(gene name)|psi-mi:MMTAG2(display_short)|uniprotkb:C1orf35(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N refseq:NP_077295.1|mint:Q9BU76|reactome:R-HSA-6798695|ensembl:ENSG00000143793(gene)|ensembl:ENST00000272139(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0034774"(secretory granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR019315|interpro:IPR039207 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:TwnLhBYwwR6yPCw3sd7g/sPHJd09606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:P48730 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-751621|uniprotkb:Q96KZ6|uniprotkb:Q9BTN5|uniprotkb:A2I2P2|ensembl:ENSP00000324464 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:kc1d_human(display_long)|uniprotkb:CSNK1D(gene name)|psi-mi:CSNK1D(display_short)|uniprotkb:HCKID(gene name synonym)|uniprotkb:Tau-protein kinase CSNK1D(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N refseq:NP_001884.2|refseq:NP_620693.1|dip:DIP-39735N|ensembl:ENSG00000141551(gene)|ensembl:ENST00000314028(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043005"(neuron projection)|go:"GO:0045296"(cadherin binding)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905426"(positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000052"(positive regulation of non-canonical Wnt signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P48730|rcsb pdb:3UYS|rcsb pdb:3UYT|rcsb pdb:3UZP|rcsb pdb:4HGT|rcsb pdb:4HNF|rcsb pdb:4KB8|rcsb pdb:4KBA|rcsb pdb:4KBC|rcsb pdb:4KBK|rcsb pdb:4TN6|rcsb pdb:4TW9|rcsb pdb:4TWC|rcsb pdb:5IH4|rcsb pdb:5IH5|rcsb pdb:5IH6|rcsb pdb:5MQV|rcsb pdb:5OKT|rcsb pdb:5W4W|rcsb pdb:6F1W|rcsb pdb:6F26|rcsb pdb:6GZM|rcsb pdb:6HMP|rcsb pdb:6HMR|rcsb pdb:6PXN|rcsb pdb:6PXO|rcsb pdb:6PXP|rcsb pdb:6RCG|rcsb pdb:6RCH|rcsb pdb:6RU6|rcsb pdb:6RU7|rcsb pdb:6RU8|reactome:R-HSA-204005|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-400253|reactome:R-HSA-5620912|reactome:R-HSA-6791226|reactome:R-HSA-8854518 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:Rz5aON17Bfduv29izmgHa/FR1/49606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:Q8NDT2 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-726721|uniprotkb:Q6QE19|uniprotkb:Q9BV96|uniprotkb:A4QPG7|ensembl:ENSP00000454545 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:rb15b_human(display_long)|uniprotkb:RNA-binding motif protein 15B(gene name synonym)|uniprotkb:RBM15B(gene name)|psi-mi:RBM15B(display_short)|uniprotkb:OTT3(gene name synonym)|uniprotkb:One-twenty two protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N refseq:NP_037418.3|ensembl:ENSG00000259956(gene)|ensembl:ENST00000563281(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016607"(nuclear speck)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR010912(Spen paralogue and orthologue C-terminal, metazoa)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012921(Spen paralogue and orthologue C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR034475|interpro:IPR034535|interpro:IPR034536|interpro:IPR035979|mint:Q8NDT2 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:uezua9bpM+Ru5qBYgb2VvhwpOo89606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:P11387 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-876302|ensembl:ENSP00000354522|uniprotkb:Q15610|uniprotkb:Q5TFY3|uniprotkb:Q9UJN0|uniprotkb:O43256|uniprotkb:Q12855|uniprotkb:Q12856|uniprotkb:A8KA78|uniprotkb:E1P5W3 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:top1_human(display_long)|uniprotkb:DNA topoisomerase I(gene name synonym)|uniprotkb:TOP1(gene name)|psi-mi:TOP1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N ensembl:ENSG00000198900(gene)|ensembl:ENST00000361337(transcript)|go:"GO:0000932"(P-body)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006265"(DNA topological change)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007623"(circadian rhythm)|go:"GO:0012501"(programmed cell death)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032922"(circadian regulation of gene expression)|refseq:NP_003277.1|dip:DIP-36356N|go:"GO:0032993"(protein-DNA complex)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042493"|go:"GO:0043204"(perikaryon)|go:"GO:0097100"(supercoiled DNA binding)|interpro:IPR001631(DNA topoisomerase I, C-terminal)|interpro:IPR008336(DNA topoisomerase I, DNA binding, eukaryotic-type)|interpro:IPR011010(DNA breaking-rejoining enzyme, catalytic core)|interpro:IPR013030(DNA topoisomerase I, DNA binding, mixed alpha/beta motif, eukaryotic-type)|interpro:IPR013034(DNA topoisomerase I, DNA binding, alpha helical motif, eukaryotic-type)|interpro:IPR013499(DNA topoisomerase I, C-terminal, eukaryotic-type)|interpro:IPR013500(DNA topoisomerase I, catalytic core, eukaryotic-type)|interpro:IPR014711(DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type)|interpro:IPR014727(DNA topoisomerase I, catalytic core, alpha/beta subdomain, eukaryotic-type)|interpro:IPR018521|interpro:IPR025834|interpro:IPR036202|mint:P11387|rcsb pdb:1A31|rcsb pdb:1A35|rcsb pdb:1A36|rcsb pdb:1EJ9|rcsb pdb:1K4S|rcsb pdb:1K4T|rcsb pdb:1LPQ|rcsb pdb:1NH3|rcsb pdb:1R49|rcsb pdb:1RR8|rcsb pdb:1RRJ|rcsb pdb:1SC7|rcsb pdb:1SEU|rcsb pdb:1T8I|rcsb pdb:1TL8|reactome:R-HSA-4615885 - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:kB+3PVybgNp2mtOmDa7x8sygFuU9606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:Q8N684 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-746909|uniprotkb:C9K0Q4|uniprotkb:Q7Z3H9|uniprotkb:Q9H025|uniprotkb:Q9H9V1|uniprotkb:B3KU04|ensembl:ENSP00000378352 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:cpsf7_human(display_long)|uniprotkb:Cleavage and polyadenylation specificity factor 59 kDa subunit(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 59 kDa subunit(gene name synonym)|uniprotkb:CPSF7(gene name)|psi-mi:CPSF7(display_short)|uniprotkb:Cleavage factor Im complex 59 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N refseq:NP_001129512.1|refseq:NP_001136037.1|refseq:NP_079087.3|refseq:XP_011543560.1|refseq:XP_011543561.1|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0016020"(membrane)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034770|interpro:IPR034772|interpro:IPR034773|interpro:IPR035979|mint:Q8N684|rcsb pdb:3N9U|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|ensembl:ENSG00000149532(gene)|ensembl:ENST00000394888(transcript)|refseq:XP_005274356.1|reactome:R-HSA-9013422 - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:bfliZhw27GRZMSQpYRZ/x/tWGh49606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:O00257 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724 - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:Q6P1X5 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-1560063|uniprotkb:O43487|uniprotkb:O43604|uniprotkb:O60668|uniprotkb:Q86WW7|uniprotkb:Q8IWK4|uniprotkb:B2RE82|ensembl:ENSP00000367406 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:taf2_human(display_long)|uniprotkb:Transcription initiation factor TFIID 150 kDa subunit(gene name synonym)|uniprotkb:TBP-associated factor 150 kDa(gene name synonym)|uniprotkb:150 kDa cofactor of initiator function(gene name synonym)|uniprotkb:RNA polymerase II TBP-associated factor subunit B(gene name synonym)|uniprotkb:TAF2(gene name)|psi-mi:TAF2(display_short)|uniprotkb:CIF150(gene name synonym)|uniprotkb:TAF2B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N refseq:NP_003175.1|dip:DIP-38921N|ensembl:ENSG00000064313(gene)|ensembl:ENST00000378164(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0033276"(transcription factor TFTC complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027268|interpro:IPR037813|interpro:IPR042097|mint:Q6P1X5|rcsb pdb:5FUR|rcsb pdb:6MZC|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042 - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:3MPkpqVRwuY2SiUxjQkcRFlq1RM9606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:Q6UN15 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-1021914|uniprotkb:Q0VGE0|uniprotkb:Q499Y4|uniprotkb:Q49AU3|uniprotkb:Q7Z608|uniprotkb:Q8WVN3|uniprotkb:Q96F80|uniprotkb:Q9H077|intact:EBI-11535474|ensembl:ENSP00000336752|uniprotkb:B4DIR3|uniprotkb:G3XAD6 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:fip1_human(display_long)|uniprotkb:Factor interacting with PAP(gene name synonym)|uniprotkb:FIP1-like 1 protein(gene name synonym)|uniprotkb:Rearranged in hypereosinophilia(gene name synonym)|uniprotkb:FIP1L1(gene name)|psi-mi:FIP1L1(display_short)|uniprotkb:FIP1(gene name synonym)|uniprotkb:RHE(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N ensembl:ENST00000306932|ensembl:ENSP00000302993|ensembl:ENSP00000336752|ensembl:ENST00000358575|ensembl:ENSP00000351383|ensembl:ENST00000507922|ensembl:ENSP00000425456|refseq:NP_001128409.1|refseq:NP_001128410.1|refseq:NP_112179.2|ensembl:ENSG00000145216(gene)|ensembl:ENST00000337488(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR007854(Fip1)|mint:Q6UN15|rcsb pdb:7K95|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|reactome:R-HSA-9673766|dip:DIP-42503N - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:41uK1l8RV99q4k4Z7K9zeG3TJHA9606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:O94842 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-948613|ensembl:ENSP00000393080|ensembl:ENSP00000477868|intact:EBI-10965337|uniprotkb:B4DPY8|uniprotkb:E7EV69|uniprotkb:B4DSM0 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:tox4_human(display_long)|uniprotkb:Epidermal Langerhans cell protein LCP1(gene name synonym)|uniprotkb:TOX4(gene name)|psi-mi:TOX4(display_short)|uniprotkb:KIAA0737(gene name synonym)|uniprotkb:C14orf92(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N ensembl:ENSG00000092203(gene)|ensembl:ENST00000448790(transcript)|ensembl:ENST00000613569(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|interpro:IPR037985|mint:O94842|refseq:NP_055643.1|refseq:NP_001290452.1 - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:tiW0mcDNOr9TsvNLVZ+f36eiNpY9606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:Q13523 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-395940|uniprotkb:Q8TDP2|uniprotkb:Q96QT7|uniprotkb:Q9UEE6|uniprotkb:Q5TAY8|uniprotkb:A8K5C9|uniprotkb:Q5D0F6|uniprotkb:Q8IVC3|intact:EBI-1058380|ensembl:ENSP00000337194|ensembl:ENSP00000433547 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:prp4b_human(display_long)|uniprotkb:PRPF4B(gene name)|psi-mi:PRPF4B(display_short)|uniprotkb:KIAA0536(gene name synonym)|uniprotkb:PRP4(gene name synonym)|uniprotkb:PRP4H(gene name synonym)|uniprotkb:PRP4K(gene name synonym)|uniprotkb:PRP4 pre-mRNA-processing factor 4 homolog(gene name synonym)|uniprotkb:PRP4 kinase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N refseq:NP_003904.3|ensembl:ENSG00000112739(gene)|ensembl:ENST00000337659(transcript)|ensembl:ENST00000480058(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR044092|mint:Q13523|rcsb pdb:4IAN|rcsb pdb:4IFC|rcsb pdb:4IIR|rcsb pdb:4IJP|rcsb pdb:6CNH|rcsb pdb:6PJJ|rcsb pdb:6PK6|rcsb pdb:6QX9|refseq:XP_016866899.1|refseq:XP_016866900.1|refseq:XP_016866901.1|refseq:XP_016866902.1|refseq:XP_016866903.1|refseq:XP_016866904.1|refseq:XP_016866905.1|refseq:XP_016866906.1|refseq:XP_016866907.1|refseq:XP_016866908.1|refseq:XP_016866909.1|refseq:XP_016866910.1|refseq:XP_016866911.1|refseq:XP_016866912.1|refseq:XP_016866913.1|refseq:XP_016866914.1|refseq:XP_016866915.1|refseq:XP_016866916.1|refseq:XP_016866917.1|refseq:XP_016866918.1|refseq:XP_016866919.1|refseq:XP_016866920.1 - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:ZklPbRvRbbVRJYqV3JkS2jG3EIc9606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:Q7L2J0 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-2371983|uniprotkb:Q9NPD4|uniprotkb:B3KP86|uniprotkb:D6W5V7|ensembl:ENSP00000308546 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:mepce_human(display_long)|uniprotkb:MEPCE(gene name)|psi-mi:MEPCE(display_short)|uniprotkb:BCDIN3(gene name synonym)|uniprotkb:Bicoid-interacting protein 3 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N refseq:XP_011514712.1|refseq:NP_001181919.1|refseq:NP_001181920.1|refseq:NP_001181921.1|refseq:NP_062552.2|ensembl:ENSG00000146834(gene)|ensembl:ENST00000310512(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001510"(RNA methylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0008171"(O-methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0016073"(snRNA metabolic process)|go:"GO:0017069"(snRNA binding)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0040031"(snRNA modification)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1905382"(positive regulation of snRNA transcription by RNA polymerase II)|go:"GO:1990276"(RNA 5'-methyltransferase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR010675(Bicoid-interacting 3)|interpro:IPR024160|interpro:IPR025714|interpro:IPR029063|interpro:IPR039772|mint:Q7L2J0|rcsb pdb:5UNA|rcsb pdb:6DCB|rcsb pdb:6DCC - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:VGhJoO3FD7nsJPVSBsKuKsPJzEM9606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:Q8WUA2 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-2513119|ensembl:ENSP00000253329|uniprotkb:B2RD34|uniprotkb:Q7Z3Q5 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:ppil4_human(display_long)|uniprotkb:PPIL4(gene name)|psi-mi:PPIL4(display_short)|uniprotkb:Cyclophilin-like protein PPIL4(gene name synonym)|uniprotkb:Rotamase PPIL4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N go:"GO:1901407"(regulation of phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029000|interpro:IPR035538|interpro:IPR035542|interpro:IPR035979|mint:Q8WUA2|reactome:R-HSA-72163|go:"GO:0005829"(cytosol)|ensembl:ENSG00000131013(gene)|ensembl:ENST00000253329(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|refseq:NP_624311.1 - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:kxM/VRcLUG5M5FAlHuuAKRBKrd89606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:Q7Z417 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-1210753|intact:EBI-10172018|uniprotkb:A1L3A7|uniprotkb:Q9P2M5|uniprotkb:A1L3A6|ensembl:ENSP00000225388 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:nufp2_human(display_long)|uniprotkb:NUFIP2(gene name)|psi-mi:NUFIP2(display_short)|uniprotkb:KIAA1321(gene name synonym)|uniprotkb:PIG1(orf name)|uniprotkb:FMRP-interacting protein 2(gene name synonym)|uniprotkb:82 kDa FMRP-interacting protein(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 1 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N refseq:NP_065823.1|dip:DIP-29023N|ensembl:ENSG00000108256(gene)|ensembl:ENST00000225388(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR032747|mint:Q7Z417 - - comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:zdbkRisveP+8g70umfbEPHTnAgk9606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:P25490 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-765538|uniprotkb:Q14935|ensembl:ENSP00000262238 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:tyy1_human(display_long)|uniprotkb:Yin and yang 1(gene name synonym)|uniprotkb:Delta transcription factor(gene name synonym)|uniprotkb:NF-E1(gene name synonym)|uniprotkb:YY1(gene name)|psi-mi:YY1(display_short)|uniprotkb:INO80S(gene name synonym)|uniprotkb:INO80 complex subunit S(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N refseq:NP_003394.1|dip:DIP-150N|ensembl:ENSG00000100811(gene)|rcsb pdb:1UBD|rcsb pdb:1ZNM|rcsb pdb:4C5I|reactome:R-HSA-5617472|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8866910|reactome:R-HSA-9018519|ensembl:ENST00000262238(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006403"(RNA localization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010225"(response to UV-C)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034696"(response to prostaglandin F)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048468"(cell development)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0051276"(chromosome organization)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017114(Transcription factor yin and yang)|interpro:IPR036236|mint:P25490 - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:OncFlxfcbNZGN68Sk39CRh9oQHc9606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:Q14247 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-351886|intact:EBI-3959948|ensembl:ENSP00000301843|ensembl:ENSP00000500756|uniprotkb:Q8N707|uniprotkb:Q96H99 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:src8_human(display_long)|uniprotkb:CTTN(gene name)|psi-mi:CTTN(display_short)|uniprotkb:EMS1(gene name synonym)|uniprotkb:Amplaxin(gene name synonym)|uniprotkb:Oncogene EMS1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N refseq:NP_005222.2|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097581"(lamellipodium organization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR015503(Cortactin)|interpro:IPR035716|interpro:IPR036028|mint:Q14247|rcsb pdb:1X69|rcsb pdb:2D1X|reactome:R-HSA-5627123|reactome:R-HSA-8856828|ensembl:ENSG00000085733(gene)|ensembl:ENSG00000288401(gene)|ensembl:ENST00000301843(transcript)|ensembl:ENST00000671805(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|refseq:NP_001171669.1|refseq:NP_612632.1|dip:DIP-33190N - - comment:"author score: 27" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:uzhAnL5Fu9Mgg9/LWeNiaYIwNVU9606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:Q86XP3 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-722353|uniprotkb:A6NML1|uniprotkb:O75619|uniprotkb:Q68G51|uniprotkb:Q96BK1|uniprotkb:Q96HR7|uniprotkb:Q9Y3V8|uniprotkb:A8KA43|intact:EBI-2555393|ensembl:ENSP00000374574|ensembl:ENSP00000463561|ensembl:ENSP00000464050 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:ddx42_human(display_long)|uniprotkb:DEAD box protein 42(gene name synonym)|uniprotkb:Splicing factor 3B-associated 125 kDa protein(gene name synonym)|uniprotkb:RNA helicase-related protein(gene name synonym)|uniprotkb:RNA helicase-like protein(gene name synonym)|uniprotkb:SF3b DEAD box protein(gene name synonym)|uniprotkb:DDX42(gene name)|psi-mi:DDX42(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N refseq:NP_031398.2|refseq:NP_987095.1|refseq:XP_006721720.1|refseq:XP_016879600.1|ensembl:ENSG00000198231(gene)|ensembl:ENST00000389924(transcript)|ensembl:ENST00000578681(transcript)|ensembl:ENST00000583590(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008104"(protein localization)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q86XP3|reactome:R-HSA-72163|reactome:R-HSA-72165 - - comment:"author score: 28" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:3vZn92rr6cO8qSZJdyq1fguSc489606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:Q6UXN9 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-1176082|uniprotkb:Q8TEB2|uniprotkb:A8K5R5|intact:EBI-2562464|ensembl:ENSP00000296490 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:wdr82_human(display_long)|uniprotkb:Protein TMEM113(gene name synonym)|uniprotkb:TMEM113(gene name synonym)|uniprotkb:WDR82(gene name)|psi-mi:WDR82(display_short)|uniprotkb:Swd2(gene name synonym)|uniprotkb:WDR82A(gene name synonym)|uniprotkb:UNQ9342/PRO34047(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N refseq:NP_079498.2|ensembl:ENSG00000164091(gene)|ensembl:ENST00000296490(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005730"(nucleolus)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|interpro:IPR037867|mint:Q6UXN9 - - comment:"author score: 30" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:0TyKYwpTLd22Cm+ihT1+n0oo12c9606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:Q9H0G5 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-5464397|uniprotkb:Q6FI71|ensembl:ENSP00000247026 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:nsrp1_human(display_long)|uniprotkb:NSRP1(gene name)|psi-mi:NSRP1(display_short)|uniprotkb:CCDC55(gene name synonym)|uniprotkb:NSRP70(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 55(gene name synonym)|uniprotkb:Nuclear speckle-related protein 70(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N refseq:NP_115517.1|refseq:NP_001248396.1|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0032502"(developmental process)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR018612|interpro:IPR042816|mint:Q9H0G5|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000126653(gene)|ensembl:ENST00000247026(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus) - - comment:"author score: 32" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:Hp8MjUsGzGZWl+Y/zyzkOxjnLc49606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60563 uniprotkb:Q96QC0 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 intact:EBI-1210346|uniprotkb:O00405|ensembl:ENSP00000365694|ensembl:ENSP00000373080|ensembl:ENSP00000389299|ensembl:ENSP00000407181|ensembl:ENSP00000407310|ensembl:ENSP00000413554|ensembl:ENSP00000416060 psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:pp1ra_human(display_long)|uniprotkb:PPP1R10(gene name)|psi-mi:PPP1R10(display_short)|uniprotkb:CAT53(gene name synonym)|uniprotkb:FB19(gene name synonym)|uniprotkb:PNUTS(gene name synonym)|uniprotkb:Phosphatase 1 nuclear targeting subunit(gene name synonym)|uniprotkb:MHC class I region proline-rich protein CAT53(gene name synonym)|uniprotkb:Protein FB19(gene name synonym)|uniprotkb:PP1-binding protein of 114 kDa(gene name synonym)|uniprotkb:p99(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477219|imex:IM-26985-463 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N refseq:XP_011513024.1|refseq:NP_002705.2|refseq:XP_006715193.1|refseq:XP_016866484.1|dip:DIP-39343N|ensembl:ENSG00000204569(gene)|ensembl:ENSG00000206489(gene)|ensembl:ENSG00000227804(gene)|ensembl:ENSG00000230995(gene)|ensembl:ENSG00000231737(gene)|ensembl:ENSG00000235291(gene)|ensembl:ENSG00000238104(gene)|ensembl:ENST00000376511(transcript)|ensembl:ENST00000383586(transcript)|ensembl:ENST00000420949(transcript)|ensembl:ENST00000424446(transcript)|ensembl:ENST00000426299(transcript)|ensembl:ENST00000429597(transcript)|ensembl:ENST00000449113(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0016604"(nuclear body)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0046872"(metal ion binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:1904290"(negative regulation of mitotic DNA damage checkpoint)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR017923|interpro:IPR035441|interpro:IPR036855|mint:Q96QC0|go:"GO:0000785"(chromatin) - - comment:"author score: 34" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rogid:ZWueXxqNFYPT0WhbfYdR3d2H2G89606 rigid:LO4f2MdSmLW8iqHdUlPqSh/DbwU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P1J9 uniprotkb:P12273 intact:EBI-930143|uniprotkb:A6NLZ8|uniprotkb:Q6PK51|uniprotkb:Q96A07|uniprotkb:Q9H245|uniprotkb:Q9H5L7|uniprotkb:B2RBR2|ensembl:ENSP00000356405 intact:EBI-1049746|uniprotkb:A0A963|uniprotkb:A0A9C3|uniprotkb:A0A9F3|uniprotkb:A4D2I1|ensembl:ENSP00000291009 psi-mi:cdc73_human(display_long)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:C1orf28(gene name synonym)|uniprotkb:HRPT2(gene name synonym)|uniprotkb:Cell division cycle protein 73 homolog(gene name synonym)|uniprotkb:Hyperparathyroidism 2 protein(gene name synonym) psi-mi:pip_human(display_long)|uniprotkb:Prolactin-induced protein(gene name synonym)|uniprotkb:Secretory actin-binding protein(gene name synonym)|uniprotkb:Gross cystic disease fluid protein 15(gene name synonym)|uniprotkb:gp17(gene name synonym)|uniprotkb:PIP(gene name)|psi-mi:PIP(display_short)|uniprotkb:GCDFP15(gene name synonym)|uniprotkb:GPIP4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477384|imex:IM-26985-233 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078805.3|dip:DIP-37884N|ensembl:ENSG00000134371(gene)|ensembl:ENST00000367435(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0031648"(protein destabilization)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR032041|interpro:IPR038103|mint:Q6P1J9|rcsb pdb:5YDE|rcsb pdb:5YDF|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-201722|reactome:R-HSA-5632684|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654 refseq:NP_002643.1|ensembl:ENSG00000159763(gene)|ensembl:ENST00000291009(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0002682"(regulation of immune system process)|go:"GO:0003779"(actin binding)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0006508"(proteolysis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019864"(IgG binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070233"(negative regulation of T cell apoptotic process)|interpro:IPR007990(Seminal vesicle autoantigen)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|mint:P12273|rcsb pdb:3ES6|reactome:R-HSA-5223345|go:"GO:0001580"(detection of chemical stimulus involved in sensory perception of bitter taste) - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nuJ2kK0petj8iBr17I2BQzxcVmE9606 rogid:/OC16zeRzFp520uPPLHh+WekPPc9606 rigid:0iBB1doabUS6/yEER16KvQuuZpY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P1J9 uniprotkb:A6NED2 intact:EBI-930143|uniprotkb:A6NLZ8|uniprotkb:Q6PK51|uniprotkb:Q96A07|uniprotkb:Q9H245|uniprotkb:Q9H5L7|uniprotkb:B2RBR2|ensembl:ENSP00000356405 intact:EBI-21552314|ensembl:ENSP00000377801|ensembl:ENSP00000451963|uniprotkb:B2RTP9|uniprotkb:Q29RX6 psi-mi:cdc73_human(display_long)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:C1orf28(gene name synonym)|uniprotkb:HRPT2(gene name synonym)|uniprotkb:Cell division cycle protein 73 homolog(gene name synonym)|uniprotkb:Hyperparathyroidism 2 protein(gene name synonym) psi-mi:rccd1_human(display_long)|uniprotkb:RCCD1(gene name)|psi-mi:RCCD1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477384|imex:IM-26985-233 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078805.3|dip:DIP-37884N|ensembl:ENSG00000134371(gene)|ensembl:ENST00000367435(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0031648"(protein destabilization)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR032041|interpro:IPR038103|mint:Q6P1J9|rcsb pdb:5YDE|rcsb pdb:5YDF|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-201722|reactome:R-HSA-5632684|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654 ensembl:ENSG00000166965(gene)|ensembl:ENST00000394258(transcript)|ensembl:ENST00000556618(transcript)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|mint:A6NED2|rcsb pdb:6F4R|rcsb pdb:6F4S|rcsb pdb:6F4T|refseq:NP_001017919.1|refseq:NP_291022.2 - - comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nuJ2kK0petj8iBr17I2BQzxcVmE9606 rogid:pJ4TNM7dmfISs5RIVzio/hBYHp09606 rigid:0iBB1doabUS6/yEER16KvQuuZpY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P1J9 uniprotkb:Q8WVC0 intact:EBI-930143|uniprotkb:A6NLZ8|uniprotkb:Q6PK51|uniprotkb:Q96A07|uniprotkb:Q9H245|uniprotkb:Q9H5L7|uniprotkb:B2RBR2|ensembl:ENSP00000356405 intact:EBI-932432|uniprotkb:Q96N99|ensembl:ENSP00000299601 psi-mi:cdc73_human(display_long)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:C1orf28(gene name synonym)|uniprotkb:HRPT2(gene name synonym)|uniprotkb:Cell division cycle protein 73 homolog(gene name synonym)|uniprotkb:Hyperparathyroidism 2 protein(gene name synonym) psi-mi:leo1_human(display_long)|uniprotkb:LEO1(gene name)|psi-mi:LEO1(display_short)|uniprotkb:RDL(gene name synonym)|uniprotkb:Replicative senescence down-regulated leo1-like protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477384|imex:IM-26985-233 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078805.3|dip:DIP-37884N|ensembl:ENSG00000134371(gene)|ensembl:ENST00000367435(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0031648"(protein destabilization)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR032041|interpro:IPR038103|mint:Q6P1J9|rcsb pdb:5YDE|rcsb pdb:5YDF|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-201722|reactome:R-HSA-5632684|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654 refseq:NP_001273359.1|refseq:NP_620147.1|dip:DIP-37885N|ensembl:ENSG00000166477(gene)|ensembl:ENST00000299601(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|interpro:IPR007149(Leo1-like protein)|mint:Q8WVC0|rcsb pdb:4M6T|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-201722|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654 - - comment:"author score: 64" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nuJ2kK0petj8iBr17I2BQzxcVmE9606 rogid:o0aaW4nxzWuPZ8/pMZpa9Qz9oEA9606 rigid:0iBB1doabUS6/yEER16KvQuuZpY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P1J9 uniprotkb:Q9GZS3 intact:EBI-930143|uniprotkb:A6NLZ8|uniprotkb:Q6PK51|uniprotkb:Q96A07|uniprotkb:Q9H245|uniprotkb:Q9H5L7|uniprotkb:B2RBR2|ensembl:ENSP00000356405 intact:EBI-358545|uniprotkb:D3DW84|uniprotkb:Q6IA22|uniprotkb:Q7Z4X4|ensembl:ENSP00000267973|ensembl:ENSP00000453801 psi-mi:cdc73_human(display_long)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:C1orf28(gene name synonym)|uniprotkb:HRPT2(gene name synonym)|uniprotkb:Cell division cycle protein 73 homolog(gene name synonym)|uniprotkb:Hyperparathyroidism 2 protein(gene name synonym) psi-mi:wdr61_human(display_long)|uniprotkb:WDR61(gene name)|psi-mi:WDR61(display_short)|uniprotkb:Meiotic recombination REC14 protein homolog(gene name synonym)|uniprotkb:SKI8 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477384|imex:IM-26985-233 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078805.3|dip:DIP-37884N|ensembl:ENSG00000134371(gene)|ensembl:ENST00000367435(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0031648"(protein destabilization)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR032041|interpro:IPR038103|mint:Q6P1J9|rcsb pdb:5YDE|rcsb pdb:5YDF|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-201722|reactome:R-HSA-5632684|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654 refseq:NP_079510.1|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9GZS3|rcsb pdb:3OW8|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-429958|reactome:R-HSA-674695|reactome:R-HSA-75955|ensembl:ENSG00000140395(gene)|ensembl:ENST00000267973(transcript)|ensembl:ENST00000558311(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0055087"(Ski complex)|reactome:R-HSA-8866654|refseq:XP_011520396.1|refseq:NP_001290176.1|refseq:NP_001290177.1|dip:DIP-36672N - - comment:"author score: 83" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nuJ2kK0petj8iBr17I2BQzxcVmE9606 rogid:yVcjv2BXXr3VFSR7OcJ/1u9L6gw9606 rigid:0iBB1doabUS6/yEER16KvQuuZpY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6P1J9 uniprotkb:Q8N7H5 intact:EBI-930143|uniprotkb:A6NLZ8|uniprotkb:Q6PK51|uniprotkb:Q96A07|uniprotkb:Q9H245|uniprotkb:Q9H5L7|uniprotkb:B2RBR2|ensembl:ENSP00000356405 intact:EBI-2607770|uniprotkb:O75239|uniprotkb:Q9H166|uniprotkb:Q9NUU9|ensembl:ENSP00000221265|uniprotkb:M0QX35 psi-mi:cdc73_human(display_long)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:C1orf28(gene name synonym)|uniprotkb:HRPT2(gene name synonym)|uniprotkb:Cell division cycle protein 73 homolog(gene name synonym)|uniprotkb:Hyperparathyroidism 2 protein(gene name synonym) psi-mi:paf1_human(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:PD2(gene name synonym)|uniprotkb:Pancreatic differentiation protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477384|imex:IM-26985-233 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078805.3|dip:DIP-37884N|ensembl:ENSG00000134371(gene)|ensembl:ENST00000367435(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0031648"(protein destabilization)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR032041|interpro:IPR038103|mint:Q6P1J9|rcsb pdb:5YDE|rcsb pdb:5YDF|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-201722|reactome:R-HSA-5632684|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654 refseq:NP_061961.2|ensembl:ENSG00000006712(gene)|ensembl:ENST00000221265(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030054"(cell junction)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|mint:Q8N7H5|rcsb pdb:4M6T|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|refseq:NP_001243755.1|dip:DIP-48673N - - comment:"author score: 157" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nuJ2kK0petj8iBr17I2BQzxcVmE9606 rogid:5Bf9gSdxgaufI30DVL8QAyVLqNk9606 rigid:0iBB1doabUS6/yEER16KvQuuZpY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UBQ7 uniprotkb:O60729 intact:EBI-372445|uniprotkb:Q9H3E9|uniprotkb:Q9UKX1|ensembl:ENSP00000313432|uniprotkb:Q5T945|uniprotkb:Q9H636 intact:EBI-970231|ensembl:ENSP00000364389|uniprotkb:A6N5X8|uniprotkb:O43183|uniprotkb:O60730|uniprotkb:Q5JU08|uniprotkb:B1AL31|uniprotkb:B1AL32|uniprotkb:A8MQ20 psi-mi:grhpr_human(display_long)|uniprotkb:MSTP035(orf name)|uniprotkb:GRHPR(gene name)|psi-mi:GRHPR(display_short)|uniprotkb:GLXR(gene name synonym) psi-mi:cc14b_human(display_long)|uniprotkb:CDC14B(gene name)|psi-mi:CDC14B(display_short)|uniprotkb:CDC14 cell division cycle 14 homolog B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25477375|imex:IM-26985-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036335.1|go:"GO:0043648"(dicarboxylic acid metabolic process)|go:"GO:0046487"(glyoxylate metabolic process)|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070402"(NADPH binding)|go:"GO:1902494"(catalytic complex)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029753|interpro:IPR036291|mint:Q9UBQ7|rcsb pdb:2GCG|rcsb pdb:2H1S|rcsb pdb:2Q50|rcsb pdb:2WWR|reactome:R-HSA-389661|ensembl:ENSG00000137106(gene)|ensembl:ENST00000318158(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0007588"(excretion)|go:"GO:0008465"(glycerate dehydrogenase activity)|go:"GO:0016618"(hydroxypyruvate reductase activity)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0030267"("glyoxylate reductase (NADP+) activity")|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0042803"(protein homodimerization activity) ensembl:ENSG00000081377(gene)|ensembl:ENST00000375241(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR029021|interpro:IPR029260|interpro:IPR044506|mint:O60729|rcsb pdb:1OHC|rcsb pdb:1OHD|rcsb pdb:1OHE|reactome:R-HSA-5687128|refseq:NP_003662.1|refseq:NP_201588.1|refseq:XP_011517460.1|refseq:NP_001070649.1|refseq:XP_016870732.1 - comment:"author score: 15" - figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qPHrh5I5wHI5MWba4zncz26cUnQ9606 rogid:b0+v+nN2fk9Eo6xMg0SlaXHWQAA9606 rigid:nWMpGOUPDXzPor0TmVdnigjDkPE false - tandem tag:n-n - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P50750 uniprotkb:O60583 intact:EBI-1383449|uniprotkb:Q5JU24|uniprotkb:Q5JU25|uniprotkb:Q5U006|uniprotkb:Q96TF1|ensembl:ENSP00000362361 intact:EBI-2836757|uniprotkb:Q5I1Y0|uniprotkb:A8KA48|uniprotkb:Q29R66|uniprotkb:Q53SR4|uniprotkb:O60582|uniprotkb:D3DP73|uniprotkb:D3DP74|ensembl:ENSP00000264157 psi-mi:cdk9_human(display_long)|uniprotkb:CDK9(gene name)|psi-mi:CDK9(display_short)|uniprotkb:CDC2L4(gene name synonym)|uniprotkb:Cell division protein kinase 9(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PITALRE(gene name synonym)|uniprotkb:Cell division cycle 2-like protein kinase 4(gene name synonym)|uniprotkb:C-2K(gene name synonym)|uniprotkb:TAK(gene name synonym)|uniprotkb:Tat-associated kinase complex catalytic subunit(gene name synonym) psi-mi:ccnt2_human(display_long)|uniprotkb:CCNT2(gene name)|psi-mi:CCNT2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477441|imex:IM-26985-153 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001252.1|dip:DIP-29016N|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000136807(gene)|ensembl:ENST00000373264(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P50750|rcsb pdb:1PF6|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA refseq:NP_001232.1|refseq:NP_490595.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019085"(early viral transcription)|go:"GO:0019086"(late viral transcription)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0097322"(7SK snRNA binding)|ensembl:ENSG00000082258(gene)|ensembl:ENST00000264157(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR028862|interpro:IPR036915|interpro:IPR043198|mint:O60583|rcsb pdb:2IVX|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|interpro:IPR013763(Cyclin-related) - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:XSEmM4b5tp/WCJCJxnQYyP0stvM9606 rogid:v1mUPCNA+Plg8UioUhIj1LL52fI9606 rigid:GpEZrIhyVznffpa+N6MQ+3YUm48 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P50750 uniprotkb:Q7L2J0 intact:EBI-1383449|uniprotkb:Q5JU24|uniprotkb:Q5JU25|uniprotkb:Q5U006|uniprotkb:Q96TF1|ensembl:ENSP00000362361 intact:EBI-2371983|uniprotkb:Q9NPD4|uniprotkb:B3KP86|uniprotkb:D6W5V7|ensembl:ENSP00000308546 psi-mi:cdk9_human(display_long)|uniprotkb:CDK9(gene name)|psi-mi:CDK9(display_short)|uniprotkb:CDC2L4(gene name synonym)|uniprotkb:Cell division protein kinase 9(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PITALRE(gene name synonym)|uniprotkb:Cell division cycle 2-like protein kinase 4(gene name synonym)|uniprotkb:C-2K(gene name synonym)|uniprotkb:TAK(gene name synonym)|uniprotkb:Tat-associated kinase complex catalytic subunit(gene name synonym) psi-mi:mepce_human(display_long)|uniprotkb:MEPCE(gene name)|psi-mi:MEPCE(display_short)|uniprotkb:BCDIN3(gene name synonym)|uniprotkb:Bicoid-interacting protein 3 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477441|imex:IM-26985-153 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001252.1|dip:DIP-29016N|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000136807(gene)|ensembl:ENST00000373264(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P50750|rcsb pdb:1PF6|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA refseq:XP_011514712.1|refseq:NP_001181919.1|refseq:NP_001181920.1|refseq:NP_001181921.1|refseq:NP_062552.2|ensembl:ENSG00000146834(gene)|ensembl:ENST00000310512(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001510"(RNA methylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0008171"(O-methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0016073"(snRNA metabolic process)|go:"GO:0017069"(snRNA binding)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0040031"(snRNA modification)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1905382"(positive regulation of snRNA transcription by RNA polymerase II)|go:"GO:1990276"(RNA 5'-methyltransferase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR010675(Bicoid-interacting 3)|interpro:IPR024160|interpro:IPR025714|interpro:IPR029063|interpro:IPR039772|mint:Q7L2J0|rcsb pdb:5UNA|rcsb pdb:6DCB|rcsb pdb:6DCC - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:XSEmM4b5tp/WCJCJxnQYyP0stvM9606 rogid:VGhJoO3FD7nsJPVSBsKuKsPJzEM9606 rigid:GpEZrIhyVznffpa+N6MQ+3YUm48 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P50750 uniprotkb:Q16543 intact:EBI-1383449|uniprotkb:Q5JU24|uniprotkb:Q5JU25|uniprotkb:Q5U006|uniprotkb:Q96TF1|ensembl:ENSP00000362361 intact:EBI-295634|uniprotkb:Q53YA2|ensembl:ENSP00000222005 psi-mi:cdk9_human(display_long)|uniprotkb:CDK9(gene name)|psi-mi:CDK9(display_short)|uniprotkb:CDC2L4(gene name synonym)|uniprotkb:Cell division protein kinase 9(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PITALRE(gene name synonym)|uniprotkb:Cell division cycle 2-like protein kinase 4(gene name synonym)|uniprotkb:C-2K(gene name synonym)|uniprotkb:TAK(gene name synonym)|uniprotkb:Tat-associated kinase complex catalytic subunit(gene name synonym) psi-mi:cdc37_human(display_long)|uniprotkb:CDC37(gene name)|psi-mi:CDC37(display_short)|uniprotkb:Hsp90 chaperone protein kinase-targeting subunit(gene name synonym)|uniprotkb:p50Cdc37(gene name synonym)|uniprotkb:CDC37A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477441|imex:IM-26985-153 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001252.1|dip:DIP-29016N|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000136807(gene)|ensembl:ENST00000373264(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P50750|rcsb pdb:1PF6|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA refseq:NP_008996.1|dip:DIP-27560N|ensembl:ENSG00000105401(gene)|ensembl:ENST00000222005(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006605"(protein targeting)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0101031"(chaperone complex)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|interpro:IPR004918(Cdc37)|interpro:IPR013855(Cdc37, N-terminal)|interpro:IPR013873(Cdc37, C-terminal)|interpro:IPR013874(Cdc37, Hsp90 binding)|interpro:IPR038189|mint:Q16543|rcsb pdb:1US7|rcsb pdb:2K5B|rcsb pdb:2N5X|rcsb pdb:2NCA|rcsb pdb:2W0G|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5HPE|reactome:R-HSA-1227986|reactome:R-HSA-1236382|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-8863795|reactome:R-HSA-9013418|reactome:R-HSA-9634285|reactome:R-HSA-9652282|reactome:R-HSA-9664565|reactome:R-HSA-9665233|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737 - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:XSEmM4b5tp/WCJCJxnQYyP0stvM9606 rogid:iajhitd2iEmd17KfpU/nMaKc4049606 rigid:GpEZrIhyVznffpa+N6MQ+3YUm48 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P50750 uniprotkb:Q13451 intact:EBI-1383449|uniprotkb:Q5JU24|uniprotkb:Q5JU25|uniprotkb:Q5U006|uniprotkb:Q96TF1|ensembl:ENSP00000362361 intact:EBI-306914|ensembl:ENSP00000349811|ensembl:ENSP00000441205|ensembl:ENSP00000444810|uniprotkb:Q5TGM6|uniprotkb:F5H7R1|uniprotkb:Q59EB8 psi-mi:cdk9_human(display_long)|uniprotkb:CDK9(gene name)|psi-mi:CDK9(display_short)|uniprotkb:CDC2L4(gene name synonym)|uniprotkb:Cell division protein kinase 9(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PITALRE(gene name synonym)|uniprotkb:Cell division cycle 2-like protein kinase 4(gene name synonym)|uniprotkb:C-2K(gene name synonym)|uniprotkb:TAK(gene name synonym)|uniprotkb:Tat-associated kinase complex catalytic subunit(gene name synonym) psi-mi:fkbp5_human(display_long)|uniprotkb:FKBP5(gene name)|psi-mi:FKBP5(display_short)|uniprotkb:AIG6(gene name synonym)|uniprotkb:FKBP51(gene name synonym)|uniprotkb:FK506-binding protein 5(gene name synonym)|uniprotkb:51 kDa FK506-binding protein(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:54 kDa progesterone receptor-associated immunophilin(gene name synonym)|uniprotkb:FKBP54(gene name synonym)|uniprotkb:FF1 antigen(gene name synonym)|uniprotkb:HSP90-binding immunophilin(gene name synonym)|uniprotkb:Androgen-regulated protein 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477441|imex:IM-26985-153 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001252.1|dip:DIP-29016N|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000136807(gene)|ensembl:ENST00000373264(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P50750|rcsb pdb:1PF6|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA ensembl:ENSG00000096060(gene)|ensembl:ENST00000357266(transcript)|ensembl:ENST00000536438(transcript)|ensembl:ENST00000539068(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005528"(FK506 binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0009617"(response to bacterium)|go:"GO:0016020"(membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type)|refseq:NP_001139247.1|refseq:NP_001139248.1|refseq:NP_004108.1|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031210|mint:Q13451|rcsb pdb:1KT0|rcsb pdb:3O5D|rcsb pdb:3O5E|rcsb pdb:3O5F|rcsb pdb:3O5G|rcsb pdb:3O5I|rcsb pdb:3O5J|rcsb pdb:3O5K|rcsb pdb:3O5L|rcsb pdb:3O5M|rcsb pdb:3O5O|rcsb pdb:3O5P|rcsb pdb:3O5Q|rcsb pdb:3O5R|rcsb pdb:4DRH|rcsb pdb:4DRI|rcsb pdb:4DRK|rcsb pdb:4DRM|rcsb pdb:4DRN|rcsb pdb:4DRO|rcsb pdb:4DRP|rcsb pdb:4DRQ|rcsb pdb:4JFI|rcsb pdb:4JFJ|rcsb pdb:4JFK|rcsb pdb:4JFL|rcsb pdb:4JFM|rcsb pdb:4R0X|rcsb pdb:4TW6|rcsb pdb:4TW7|rcsb pdb:4TX0|rcsb pdb:4W9O|rcsb pdb:4W9P|rcsb pdb:4W9Q|rcsb pdb:5BXJ|rcsb pdb:5DIT|rcsb pdb:5DIU|rcsb pdb:5DIV|rcsb pdb:5NJX|rcsb pdb:5OBK|rcsb pdb:5OMP|rcsb pdb:6SAF|rcsb pdb:6TX4|rcsb pdb:6TX5|rcsb pdb:6TX6|rcsb pdb:6TX7|rcsb pdb:6TX8|rcsb pdb:6TX9|rcsb pdb:6TXX|rcsb pdb:7A6W|rcsb pdb:7A6X|rcsb pdb:7AOT|rcsb pdb:7AOU|rcsb pdb:7AWF|rcsb pdb:7AWX|rcsb pdb:7B9Y|rcsb pdb:7B9Z|rcsb pdb:7BA0|reactome:R-HSA-3371497|reactome:R-HSA-8939211|reactome:R-HSA-9022699|refseq:NP_001139249.1|dip:DIP-27597N - - comment:"author score: 35" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:XSEmM4b5tp/WCJCJxnQYyP0stvM9606 rogid:m2Bnn01E13sovh3BwG71Pgqjdx89606 rigid:GpEZrIhyVznffpa+N6MQ+3YUm48 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P50750 uniprotkb:O60563 intact:EBI-1383449|uniprotkb:Q5JU24|uniprotkb:Q5JU25|uniprotkb:Q5U006|uniprotkb:Q96TF1|ensembl:ENSP00000362361 intact:EBI-2479671|ensembl:ENSP00000261900|uniprotkb:O60581|uniprotkb:A9XU13|uniprotkb:E7EX76 psi-mi:cdk9_human(display_long)|uniprotkb:CDK9(gene name)|psi-mi:CDK9(display_short)|uniprotkb:CDC2L4(gene name synonym)|uniprotkb:Cell division protein kinase 9(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PITALRE(gene name synonym)|uniprotkb:Cell division cycle 2-like protein kinase 4(gene name synonym)|uniprotkb:C-2K(gene name synonym)|uniprotkb:TAK(gene name synonym)|uniprotkb:Tat-associated kinase complex catalytic subunit(gene name synonym) psi-mi:ccnt1_human(display_long)|uniprotkb:CCNT1(gene name)|psi-mi:CCNT1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477441|imex:IM-26985-153 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001252.1|dip:DIP-29016N|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000136807(gene)|ensembl:ENST00000373264(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P50750|rcsb pdb:1PF6|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA go:"GO:0097322"(7SK snRNA binding)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR006671(Cyclin, N-terminal)|go:"GO:0070691"(P-TEFb complex)|interpro:IPR013763(Cyclin-related)|interpro:IPR028863|interpro:IPR036915|interpro:IPR043198|mint:O60563|rcsb pdb:2PK2|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000129315(gene)|ensembl:ENST00000261900(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051301"(cell division)|go:"GO:0061575"(cyclin-dependent protein serine/threonine kinase activator activity)|go:"GO:0070063"(RNA polymerase binding)|refseq:NP_001231.2|refseq:NP_001264771.1|dip:DIP-29891N - - comment:"author score: 49" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:XSEmM4b5tp/WCJCJxnQYyP0stvM9606 rogid:y80GILqwBbb5hMtl/4U1Y/vNx909606 rigid:GpEZrIhyVznffpa+N6MQ+3YUm48 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P11802 uniprotkb:P82930 intact:EBI-295644|uniprotkb:O00576|uniprotkb:Q6FG61|uniprotkb:B4DNF9|uniprotkb:B2R9A0|ensembl:ENSP00000257904 intact:EBI-1048516|uniprotkb:Q9BVI7|ensembl:ENSP00000380531 psi-mi:cdk4_human(display_long)|uniprotkb:CDK4(gene name)|psi-mi:CDK4(display_short)|uniprotkb:Cell division protein kinase 4(gene name synonym)|uniprotkb:PSK-J3(gene name synonym) psi-mi:rt34_human(display_long)|uniprotkb:MRPS34(gene name)|psi-mi:MRPS34(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein mS34(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477405|imex:IM-26985-309 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000066.1|dip:DIP-875N|ensembl:ENSG00000135446(gene)|ensembl:ENST00000257904(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000785"(chromatin)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0030332"(cyclin binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033574"(response to testosterone)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042493"|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046890"(regulation of lipid biosynthetic process)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050994"(regulation of lipid catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060260"(regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060612"(adipose tissue development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0097129"(cyclin D2-CDK4 complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904628"(cellular response to phorbol 13-acetate 12-myristate)|go:"GO:1904637"(cellular response to ionomycin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P11802|rcsb pdb:1LD2|rcsb pdb:2W96|rcsb pdb:2W99|rcsb pdb:2W9F|rcsb pdb:2W9Z|rcsb pdb:3G33|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:6P8G|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-2559580|rcsb pdb:6P8E|rcsb pdb:6P8F|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-3214858|reactome:R-HSA-381340|reactome:R-HSA-69231|reactome:R-HSA-75815|reactome:R-HSA-8849470|reactome:R-HSA-8878166|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9630791|reactome:R-HSA-9630794|reactome:R-HSA-9632697|reactome:R-HSA-9632700|reactome:R-HSA-9661069 refseq:NP_001287829.1|refseq:NP_076425.1|ensembl:ENSG00000074071(gene)|ensembl:ENST00000397375(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR032053|mint:P82930|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pxIzF9EkX+gMz7zj/TDiytYtsOc9606 rogid:UTZkYPSJqThFKwoB7D5sH6g0zuc9606 rigid:IUSOYtSF6ODC9NJy2UixFM8FmqQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P11802 uniprotkb:P53007 intact:EBI-295644|uniprotkb:O00576|uniprotkb:Q6FG61|uniprotkb:B4DNF9|uniprotkb:B2R9A0|ensembl:ENSP00000257904 intact:EBI-359163|uniprotkb:Q9BSK6|uniprotkb:A8K8E8|ensembl:ENSP00000215882 psi-mi:cdk4_human(display_long)|uniprotkb:CDK4(gene name)|psi-mi:CDK4(display_short)|uniprotkb:Cell division protein kinase 4(gene name synonym)|uniprotkb:PSK-J3(gene name synonym) psi-mi:txtp_human(display_long)|uniprotkb:SLC25A1(gene name)|psi-mi:SLC25A1(display_short)|uniprotkb:SLC20A3(gene name synonym)|uniprotkb:Citrate transport protein(gene name synonym)|uniprotkb:Tricarboxylate carrier protein(gene name synonym)|uniprotkb:Solute carrier family 25 member 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477405|imex:IM-26985-309 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000066.1|dip:DIP-875N|ensembl:ENSG00000135446(gene)|ensembl:ENST00000257904(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000785"(chromatin)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0030332"(cyclin binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033574"(response to testosterone)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042493"|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046890"(regulation of lipid biosynthetic process)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050994"(regulation of lipid catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060260"(regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060612"(adipose tissue development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0097129"(cyclin D2-CDK4 complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904628"(cellular response to phorbol 13-acetate 12-myristate)|go:"GO:1904637"(cellular response to ionomycin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P11802|rcsb pdb:1LD2|rcsb pdb:2W96|rcsb pdb:2W99|rcsb pdb:2W9F|rcsb pdb:2W9Z|rcsb pdb:3G33|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:6P8G|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-2559580|rcsb pdb:6P8E|rcsb pdb:6P8F|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-3214858|reactome:R-HSA-381340|reactome:R-HSA-69231|reactome:R-HSA-75815|reactome:R-HSA-8849470|reactome:R-HSA-8878166|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9630791|reactome:R-HSA-9630794|reactome:R-HSA-9632697|reactome:R-HSA-9632700|reactome:R-HSA-9661069 refseq:NP_005975.1|ensembl:ENSG00000100075(gene)|ensembl:ENST00000215882(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006843"(mitochondrial citrate transmembrane transport)|go:"GO:0015137"(citrate transmembrane transporter activity)|go:"GO:0015142"(tricarboxylic acid transmembrane transporter activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0046949"(fatty-acyl-CoA biosynthetic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071913"(citrate secondary active transmembrane transporter activity)|interpro:IPR002067(Mitochondrial carrier protein)|interpro:IPR018108|interpro:IPR023395|mint:P53007|reactome:R-HSA-70263|reactome:R-HSA-75105 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pxIzF9EkX+gMz7zj/TDiytYtsOc9606 rogid:MB0RrMAQme4F8M4IivU1AqUxlgA9606 rigid:IUSOYtSF6ODC9NJy2UixFM8FmqQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P11802 uniprotkb:P43307 intact:EBI-295644|uniprotkb:O00576|uniprotkb:Q6FG61|uniprotkb:B4DNF9|uniprotkb:B2R9A0|ensembl:ENSP00000257904 intact:EBI-714168|uniprotkb:A8K685|uniprotkb:Q9TNQ8|uniprotkb:Q53GX2|uniprotkb:Q53H19|uniprotkb:Q5TAM3|uniprotkb:Q6IB43|uniprotkb:Q8NBH9|uniprotkb:Q96IA2|uniprotkb:Q9UN49|ensembl:ENSP00000244763 psi-mi:cdk4_human(display_long)|uniprotkb:CDK4(gene name)|psi-mi:CDK4(display_short)|uniprotkb:Cell division protein kinase 4(gene name synonym)|uniprotkb:PSK-J3(gene name synonym) psi-mi:ssra_human(display_long)|uniprotkb:Signal sequence receptor subunit alpha(gene name synonym)|uniprotkb:SSR1(gene name)|psi-mi:SSR1(display_short)|uniprotkb:TRAPA(gene name synonym)|uniprotkb:PSEC0262(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477405|imex:IM-26985-309 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000066.1|dip:DIP-875N|ensembl:ENSG00000135446(gene)|ensembl:ENST00000257904(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000785"(chromatin)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0030332"(cyclin binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033574"(response to testosterone)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042493"|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046890"(regulation of lipid biosynthetic process)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050994"(regulation of lipid catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060260"(regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060612"(adipose tissue development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0097129"(cyclin D2-CDK4 complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904628"(cellular response to phorbol 13-acetate 12-myristate)|go:"GO:1904637"(cellular response to ionomycin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P11802|rcsb pdb:1LD2|rcsb pdb:2W96|rcsb pdb:2W99|rcsb pdb:2W9F|rcsb pdb:2W9Z|rcsb pdb:3G33|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:6P8G|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-2559580|rcsb pdb:6P8E|rcsb pdb:6P8F|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-3214858|reactome:R-HSA-381340|reactome:R-HSA-69231|reactome:R-HSA-75815|reactome:R-HSA-8849470|reactome:R-HSA-8878166|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9630791|reactome:R-HSA-9630794|reactome:R-HSA-9632697|reactome:R-HSA-9632700|reactome:R-HSA-9661069 refseq:NP_003135.2|ensembl:ENSG00000124783(gene)|ensembl:ENST00000244763(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016021"(integral component of membrane)|interpro:IPR005595("Translocon-associated protein (TRAP), alpha subunit")|mint:P43307|reactome:R-HSA-1799339|reactome:R-HSA-381038|refseq:NP_001278937.1 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pxIzF9EkX+gMz7zj/TDiytYtsOc9606 rogid:OhI1z1wbH8LEZaiv+OLChzMvT+A9606 rigid:IUSOYtSF6ODC9NJy2UixFM8FmqQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P11802 uniprotkb:P28482 intact:EBI-295644|uniprotkb:O00576|uniprotkb:Q6FG61|uniprotkb:B4DNF9|uniprotkb:B2R9A0|ensembl:ENSP00000257904 intact:EBI-959949|ensembl:ENSP00000215832|ensembl:ENSP00000381803|uniprotkb:A8CZ64 psi-mi:cdk4_human(display_long)|uniprotkb:CDK4(gene name)|psi-mi:CDK4(display_short)|uniprotkb:Cell division protein kinase 4(gene name synonym)|uniprotkb:PSK-J3(gene name synonym) psi-mi:mk01_human(display_long)|uniprotkb:MAPK1(gene name)|psi-mi:MAPK1(display_short)|uniprotkb:ERK2(gene name synonym)|uniprotkb:PRKM1(gene name synonym)|uniprotkb:Extracellular signal-regulated kinase 2(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 2(gene name synonym)|uniprotkb:MAP kinase isoform p42(gene name synonym)|uniprotkb:ERT1(gene name synonym)|uniprotkb:PRKM2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477405|imex:IM-26985-309 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000066.1|dip:DIP-875N|ensembl:ENSG00000135446(gene)|ensembl:ENST00000257904(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000785"(chromatin)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0030332"(cyclin binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033574"(response to testosterone)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042493"|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046890"(regulation of lipid biosynthetic process)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050994"(regulation of lipid catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060260"(regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060612"(adipose tissue development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0097129"(cyclin D2-CDK4 complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904628"(cellular response to phorbol 13-acetate 12-myristate)|go:"GO:1904637"(cellular response to ionomycin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P11802|rcsb pdb:1LD2|rcsb pdb:2W96|rcsb pdb:2W99|rcsb pdb:2W9F|rcsb pdb:2W9Z|rcsb pdb:3G33|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:6P8G|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-2559580|rcsb pdb:6P8E|rcsb pdb:6P8F|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-3214858|reactome:R-HSA-381340|reactome:R-HSA-69231|reactome:R-HSA-75815|reactome:R-HSA-8849470|reactome:R-HSA-8878166|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9630791|reactome:R-HSA-9630794|reactome:R-HSA-9632697|reactome:R-HSA-9632700|reactome:R-HSA-9661069 reactome:R-HSA-112411|reactome:R-HSA-1295596|reactome:R-HSA-162658|reactome:R-HSA-170968|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2029482|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2871796|reactome:R-HSA-3371453|reactome:R-HSA-375165|reactome:R-HSA-437239|reactome:R-HSA-444257|reactome:R-HSA-445144|reactome:R-HSA-450341|reactome:R-HSA-456926|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5663213|refseq:NP_002736.3|refseq:NP_620407.1|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019858"(cytosine metabolic process)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030278"(regulation of ossification)|go:"GO:0030424"(axon)|go:"GO:0030641"(regulation of cellular pH)|go:"GO:0030878"(thyroid gland development)|go:"GO:0031143"(pseudopodium)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035094"(response to nicotine)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0038127"(ERBB signaling pathway)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042473"(outer ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0043627"(response to estrogen)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046697"(decidualization)|go:"GO:0048538"(thymus development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051403"(stress-activated MAPK cascade)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060020"(Bergmann glial cell differentiation)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060324"(face development)|go:"GO:0060425"(lung morphogenesis)|go:"GO:0060440"(trachea formation)|go:"GO:0060716"(labyrinthine layer blood vessel development)|go:"GO:0061308"(cardiac neural crest cell development involved in heart development)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070849"(response to epidermal growth factor)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0090170"(regulation of Golgi inheritance)|go:"GO:0097011"(cellular response to granulocyte macrophage colony-stimulating factor stimulus)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0120041"(positive regulation of macrophage proliferation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1904355"(positive regulation of telomere capping)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR003527(MAP kinase, conserved site)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR008349(ERK1/2 MAP kinase)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P28482|rcsb pdb:1PME|go:"GO:0072686"(mitotic spindle)|rcsb pdb:1TVO|rcsb pdb:1WZY|rcsb pdb:2OJG|rcsb pdb:2OJI|rcsb pdb:2OJJ|rcsb pdb:2Y9Q|rcsb pdb:3D42|rcsb pdb:3D44|rcsb pdb:3I5Z|rcsb pdb:3I60|rcsb pdb:3SA0|rcsb pdb:3TEI|rcsb pdb:3W55|rcsb pdb:4FMQ|rcsb pdb:4FUX|rcsb pdb:4FUY|rcsb pdb:4FV0|rcsb pdb:4FV1|rcsb pdb:4FV2|rcsb pdb:4FV3|rcsb pdb:4FV4|rcsb pdb:4FV5|rcsb pdb:4FV6|rcsb pdb:4FV7|rcsb pdb:4FV8|rcsb pdb:4FV9|rcsb pdb:4G6N|rcsb pdb:4G6O|rcsb pdb:4H3P|rcsb pdb:4H3Q|rcsb pdb:4IZ5|rcsb pdb:4IZ7|rcsb pdb:4IZA|rcsb pdb:4N0S|rcsb pdb:4NIF|rcsb pdb:4O6E|rcsb pdb:4QP1|rcsb pdb:4QP2|rcsb pdb:4QP3|rcsb pdb:4QP4|rcsb pdb:4QP6|rcsb pdb:4QP7|rcsb pdb:4QP8|rcsb pdb:4QP9|rcsb pdb:4QPA|rcsb pdb:4QTA|rcsb pdb:4QTE|rcsb pdb:4XJ0|rcsb pdb:4ZXT|rcsb pdb:4ZZM|rcsb pdb:4ZZN|rcsb pdb:4ZZO|rcsb pdb:5AX3|rcsb pdb:5BUE|rcsb pdb:5BUI|rcsb pdb:5BUJ|rcsb pdb:5BVD|rcsb pdb:5BVE|rcsb pdb:5BVF|rcsb pdb:5K4I|rcsb pdb:5LCJ|rcsb pdb:5LCK|rcsb pdb:5NGU|rcsb pdb:5NHF|rcsb pdb:5NHH|rcsb pdb:5NHJ|rcsb pdb:5NHL|rcsb pdb:5NHO|rcsb pdb:5NHP|rcsb pdb:5NHV|rcsb pdb:5V60|rcsb pdb:5V61|rcsb pdb:5V62|rcsb pdb:5WP1|rcsb pdb:6D5Y|rcsb pdb:6DMG|rcsb pdb:6G54|rcsb pdb:6G8X|rcsb pdb:6G91|rcsb pdb:6G92|rcsb pdb:6G93|rcsb pdb:6G97|rcsb pdb:6G9A|rcsb pdb:6G9D|rcsb pdb:6G9H|rcsb pdb:6G9J|rcsb pdb:6G9K|rcsb pdb:6G9M|rcsb pdb:6G9N|rcsb pdb:6GDM|rcsb pdb:6GDQ|rcsb pdb:6GE0|rcsb pdb:6GJB|rcsb pdb:6GJD|rcsb pdb:6NBS|rcsb pdb:6OPG|rcsb pdb:6OPH|rcsb pdb:6OPI|rcsb pdb:6Q7K|rcsb pdb:6Q7S|rcsb pdb:6Q7T|rcsb pdb:6QA1|rcsb pdb:6QA3|rcsb pdb:6QA4|rcsb pdb:6QAG|rcsb pdb:6QAH|rcsb pdb:6QAL|rcsb pdb:6QAQ|rcsb pdb:6QAW|rcsb pdb:6RQ4|rcsb pdb:6SLG|reactome:R-HSA-111995|reactome:R-HSA-112409|ensembl:ENSG00000100030(gene)|ensembl:ENST00000215832(transcript)|ensembl:ENST00000398822(transcript)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004707"(MAP kinase activity)|go:"GO:0004708"(MAP kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007568"(aging)|go:"GO:0007611"(learning or memory)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010759"(positive regulation of macrophage chemotaxis)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015966"(diadenosine tetraphosphate biosynthetic process)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006935"(chemotaxis)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|reactome:R-HSA-5668599|reactome:R-HSA-5673001|reactome:R-HSA-5674135|reactome:R-HSA-5674499|reactome:R-HSA-5675221|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-74749|reactome:R-HSA-879415|reactome:R-HSA-881907|reactome:R-HSA-8939211|reactome:R-HSA-8940973|reactome:R-HSA-8943724|reactome:R-HSA-9627069|reactome:R-HSA-9634635|reactome:R-HSA-9634638|reactome:R-HSA-9635465|reactome:R-HSA-9649948|reactome:R-HSA-9652169|reactome:R-HSA-9652817|reactome:R-HSA-9656223|reactome:R-HSA-9664422|reactome:R-HSA-982772|dip:DIP-519N|ensembl:ENSP00000215832|ensembl:ENSP00000381803|ensembl:ENST00000544786|ensembl:ENSP00000440842 - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pxIzF9EkX+gMz7zj/TDiytYtsOc9606 rogid:odzhd70I/8uWedx0+gF38lhe60I9606 rigid:IUSOYtSF6ODC9NJy2UixFM8FmqQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P11802 uniprotkb:Q16543 intact:EBI-295644|uniprotkb:O00576|uniprotkb:Q6FG61|uniprotkb:B4DNF9|uniprotkb:B2R9A0|ensembl:ENSP00000257904 intact:EBI-295634|uniprotkb:Q53YA2|ensembl:ENSP00000222005 psi-mi:cdk4_human(display_long)|uniprotkb:CDK4(gene name)|psi-mi:CDK4(display_short)|uniprotkb:Cell division protein kinase 4(gene name synonym)|uniprotkb:PSK-J3(gene name synonym) psi-mi:cdc37_human(display_long)|uniprotkb:CDC37(gene name)|psi-mi:CDC37(display_short)|uniprotkb:Hsp90 chaperone protein kinase-targeting subunit(gene name synonym)|uniprotkb:p50Cdc37(gene name synonym)|uniprotkb:CDC37A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477405|imex:IM-26985-309 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000066.1|dip:DIP-875N|ensembl:ENSG00000135446(gene)|ensembl:ENST00000257904(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000785"(chromatin)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0030332"(cyclin binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033574"(response to testosterone)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042493"|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046890"(regulation of lipid biosynthetic process)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050994"(regulation of lipid catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060260"(regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060612"(adipose tissue development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0097129"(cyclin D2-CDK4 complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904628"(cellular response to phorbol 13-acetate 12-myristate)|go:"GO:1904637"(cellular response to ionomycin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P11802|rcsb pdb:1LD2|rcsb pdb:2W96|rcsb pdb:2W99|rcsb pdb:2W9F|rcsb pdb:2W9Z|rcsb pdb:3G33|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:6P8G|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-2559580|rcsb pdb:6P8E|rcsb pdb:6P8F|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-3214858|reactome:R-HSA-381340|reactome:R-HSA-69231|reactome:R-HSA-75815|reactome:R-HSA-8849470|reactome:R-HSA-8878166|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9630791|reactome:R-HSA-9630794|reactome:R-HSA-9632697|reactome:R-HSA-9632700|reactome:R-HSA-9661069 refseq:NP_008996.1|dip:DIP-27560N|ensembl:ENSG00000105401(gene)|ensembl:ENST00000222005(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006605"(protein targeting)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0101031"(chaperone complex)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|interpro:IPR004918(Cdc37)|interpro:IPR013855(Cdc37, N-terminal)|interpro:IPR013873(Cdc37, C-terminal)|interpro:IPR013874(Cdc37, Hsp90 binding)|interpro:IPR038189|mint:Q16543|rcsb pdb:1US7|rcsb pdb:2K5B|rcsb pdb:2N5X|rcsb pdb:2NCA|rcsb pdb:2W0G|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5HPE|reactome:R-HSA-1227986|reactome:R-HSA-1236382|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-8863795|reactome:R-HSA-9013418|reactome:R-HSA-9634285|reactome:R-HSA-9652282|reactome:R-HSA-9664565|reactome:R-HSA-9665233|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737 - - comment:"author score: 38" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pxIzF9EkX+gMz7zj/TDiytYtsOc9606 rogid:iajhitd2iEmd17KfpU/nMaKc4049606 rigid:IUSOYtSF6ODC9NJy2UixFM8FmqQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P11802 uniprotkb:P42772 intact:EBI-295644|uniprotkb:O00576|uniprotkb:Q6FG61|uniprotkb:B4DNF9|uniprotkb:B2R9A0|ensembl:ENSP00000257904 intact:EBI-711280|ensembl:ENSP00000276925|uniprotkb:Q6FI09|uniprotkb:O15125 psi-mi:cdk4_human(display_long)|uniprotkb:CDK4(gene name)|psi-mi:CDK4(display_short)|uniprotkb:Cell division protein kinase 4(gene name synonym)|uniprotkb:PSK-J3(gene name synonym) psi-mi:cdn2b_human(display_long)|uniprotkb:CDKN2B(gene name)|psi-mi:CDKN2B(display_short)|uniprotkb:MTS2(gene name synonym)|uniprotkb:p14-INK4b(gene name synonym)|uniprotkb:p15-INK4b(gene name synonym)|uniprotkb:Multiple tumor suppressor 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477405|imex:IM-26985-309 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000066.1|dip:DIP-875N|ensembl:ENSG00000135446(gene)|ensembl:ENST00000257904(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000785"(chromatin)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0030332"(cyclin binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033574"(response to testosterone)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042493"|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046890"(regulation of lipid biosynthetic process)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050994"(regulation of lipid catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060260"(regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060612"(adipose tissue development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0097129"(cyclin D2-CDK4 complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904628"(cellular response to phorbol 13-acetate 12-myristate)|go:"GO:1904637"(cellular response to ionomycin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P11802|rcsb pdb:1LD2|rcsb pdb:2W96|rcsb pdb:2W99|rcsb pdb:2W9F|rcsb pdb:2W9Z|rcsb pdb:3G33|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:6P8G|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-2559580|rcsb pdb:6P8E|rcsb pdb:6P8F|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-3214858|reactome:R-HSA-381340|reactome:R-HSA-69231|reactome:R-HSA-75815|reactome:R-HSA-8849470|reactome:R-HSA-8878166|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9630791|reactome:R-HSA-9630794|reactome:R-HSA-9632697|reactome:R-HSA-9632700|reactome:R-HSA-9661069 refseq:NP_004927.2|refseq:NP_511042.1|ensembl:ENSG00000147883(gene)|ensembl:ENST00000276925(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030219"(megakaryocyte differentiation)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0031670"(cellular response to nutrient)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0048536"(spleen development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070316"(regulation of G0 to G1 transition)|go:"GO:0090398"(cellular senescence)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR036770|mint:P42772|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-69231 - - comment:"author score: 48" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pxIzF9EkX+gMz7zj/TDiytYtsOc9606 rogid:LPYMnoSMJDDOXTJ4BrDYyv9gXm09606 rigid:IUSOYtSF6ODC9NJy2UixFM8FmqQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P11802 uniprotkb:P55273 intact:EBI-295644|uniprotkb:O00576|uniprotkb:Q6FG61|uniprotkb:B4DNF9|uniprotkb:B2R9A0|ensembl:ENSP00000257904 intact:EBI-745859|uniprotkb:Q13102|uniprotkb:Q6FGE9|ensembl:ENSP00000337056|ensembl:ENSP00000377224 psi-mi:cdk4_human(display_long)|uniprotkb:CDK4(gene name)|psi-mi:CDK4(display_short)|uniprotkb:Cell division protein kinase 4(gene name synonym)|uniprotkb:PSK-J3(gene name synonym) psi-mi:cdn2d_human(display_long)|uniprotkb:p19-INK4d(gene name synonym)|uniprotkb:CDKN2D(gene name)|psi-mi:CDKN2D(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477405|imex:IM-26985-309 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000066.1|dip:DIP-875N|ensembl:ENSG00000135446(gene)|ensembl:ENST00000257904(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000785"(chromatin)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0030332"(cyclin binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033574"(response to testosterone)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042493"|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046890"(regulation of lipid biosynthetic process)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050994"(regulation of lipid catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060260"(regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060612"(adipose tissue development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0097129"(cyclin D2-CDK4 complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904628"(cellular response to phorbol 13-acetate 12-myristate)|go:"GO:1904637"(cellular response to ionomycin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P11802|rcsb pdb:1LD2|rcsb pdb:2W96|rcsb pdb:2W99|rcsb pdb:2W9F|rcsb pdb:2W9Z|rcsb pdb:3G33|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:6P8G|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-2559580|rcsb pdb:6P8E|rcsb pdb:6P8F|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-3214858|reactome:R-HSA-381340|reactome:R-HSA-69231|reactome:R-HSA-75815|reactome:R-HSA-8849470|reactome:R-HSA-8878166|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9630791|reactome:R-HSA-9630794|reactome:R-HSA-9632697|reactome:R-HSA-9632700|reactome:R-HSA-9661069 refseq:NP_001791.1|refseq:NP_524145.1|ensembl:ENSG00000129355(gene)|ensembl:ENST00000335766(transcript)|ensembl:ENST00000393599(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009411"(response to UV)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0033280"(response to vitamin D)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0048102"(autophagic cell death)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902807"(negative regulation of cell cycle G1/S phase transition)|go:"GO:0097129"(cyclin D2-CDK4 complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:P55273|rcsb pdb:1BD8|rcsb pdb:1BI8|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-69231|dip:DIP-6109N - - comment:"author score: 64" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pxIzF9EkX+gMz7zj/TDiytYtsOc9606 rogid:NAUbd6nKPP8MZGU1B0zlo+Du3Zs9606 rigid:IUSOYtSF6ODC9NJy2UixFM8FmqQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P11802 uniprotkb:P54819 intact:EBI-295644|uniprotkb:O00576|uniprotkb:Q6FG61|uniprotkb:B4DNF9|uniprotkb:B2R9A0|ensembl:ENSP00000257904 intact:EBI-1056291|uniprotkb:Q16856|uniprotkb:Q5TIF7|uniprotkb:Q8TCY2|uniprotkb:Q8TCY3|uniprotkb:A8K6L1|uniprotkb:B4DHH7|uniprotkb:B4DL64|uniprotkb:Q5EB54|ensembl:ENSP00000499935 psi-mi:cdk4_human(display_long)|uniprotkb:CDK4(gene name)|psi-mi:CDK4(display_short)|uniprotkb:Cell division protein kinase 4(gene name synonym)|uniprotkb:PSK-J3(gene name synonym) psi-mi:kad2_human(display_long)|uniprotkb:AK2(gene name)|psi-mi:AK2(display_short)|uniprotkb:ADK2(gene name synonym)|uniprotkb:ATP-AMP transphosphorylase 2(gene name synonym)|uniprotkb:"ATP:AMP phosphotransferase"(gene name synonym)|uniprotkb:Adenylate monophosphate kinase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477405|imex:IM-26985-309 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000066.1|dip:DIP-875N|ensembl:ENSG00000135446(gene)|ensembl:ENST00000257904(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000785"(chromatin)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0030332"(cyclin binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033574"(response to testosterone)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042493"|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046890"(regulation of lipid biosynthetic process)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050994"(regulation of lipid catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060260"(regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060612"(adipose tissue development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0097129"(cyclin D2-CDK4 complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904628"(cellular response to phorbol 13-acetate 12-myristate)|go:"GO:1904637"(cellular response to ionomycin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P11802|rcsb pdb:1LD2|rcsb pdb:2W96|rcsb pdb:2W99|rcsb pdb:2W9F|rcsb pdb:2W9Z|rcsb pdb:3G33|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:6P8G|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-2559580|rcsb pdb:6P8E|rcsb pdb:6P8F|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-3214858|reactome:R-HSA-381340|reactome:R-HSA-69231|reactome:R-HSA-75815|reactome:R-HSA-8849470|reactome:R-HSA-8878166|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9630791|reactome:R-HSA-9630794|reactome:R-HSA-9632697|reactome:R-HSA-9632700|reactome:R-HSA-9661069 refseq:NP_001186128.1|refseq:NP_001616.1|refseq:NP_037543.1|refseq:NP_001306068.1|refseq:NP_001306069.1|ensembl:ENSG00000004455(gene)|ensembl:ENST00000672715(transcript)|go:"GO:0004017"(adenylate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0006172"(ADP biosynthetic process)|go:"GO:0015949"(nucleobase-containing small molecule interconversion)|go:"GO:0046033"(AMP metabolic process)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097226"(sperm mitochondrial sheath)|interpro:IPR000850(Adenylate kinase)|interpro:IPR006259(Adenylate kinase, subfamily)|interpro:IPR007862(Adenylate kinase, zinc-finger lid region)|interpro:IPR027417|interpro:IPR028587|interpro:IPR033690|mint:P54819|rcsb pdb:2C9Y|reactome:R-HSA-499943 - - comment:"author score: 71" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pxIzF9EkX+gMz7zj/TDiytYtsOc9606 rogid:pzIKBBzoytYPw3r87WMBueRNpWw9606 rigid:IUSOYtSF6ODC9NJy2UixFM8FmqQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P11802 uniprotkb:P42773 intact:EBI-295644|uniprotkb:O00576|uniprotkb:Q6FG61|uniprotkb:B4DNF9|uniprotkb:B2R9A0|ensembl:ENSP00000257904 intact:EBI-711290|uniprotkb:Q8TB83|ensembl:ENSP00000262662|ensembl:ENSP00000360826|ensembl:ENSP00000379452 psi-mi:cdk4_human(display_long)|uniprotkb:CDK4(gene name)|psi-mi:CDK4(display_short)|uniprotkb:Cell division protein kinase 4(gene name synonym)|uniprotkb:PSK-J3(gene name synonym) psi-mi:cdn2c_human(display_long)|uniprotkb:CDKN2C(gene name)|psi-mi:CDKN2C(display_short)|uniprotkb:CDKN6(gene name synonym)|uniprotkb:p18-INK4c(gene name synonym)|uniprotkb:Cyclin-dependent kinase 6 inhibitor(gene name synonym)|uniprotkb:p18-INK6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477405|imex:IM-26985-309 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000066.1|dip:DIP-875N|ensembl:ENSG00000135446(gene)|ensembl:ENST00000257904(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000785"(chromatin)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0030332"(cyclin binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033574"(response to testosterone)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042493"|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046890"(regulation of lipid biosynthetic process)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050994"(regulation of lipid catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060260"(regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060612"(adipose tissue development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0097129"(cyclin D2-CDK4 complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904628"(cellular response to phorbol 13-acetate 12-myristate)|go:"GO:1904637"(cellular response to ionomycin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P11802|rcsb pdb:1LD2|rcsb pdb:2W96|rcsb pdb:2W99|rcsb pdb:2W9F|rcsb pdb:2W9Z|rcsb pdb:3G33|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:6P8G|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-2559580|rcsb pdb:6P8E|rcsb pdb:6P8F|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-3214858|reactome:R-HSA-381340|reactome:R-HSA-69231|reactome:R-HSA-75815|reactome:R-HSA-8849470|reactome:R-HSA-8878166|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9630791|reactome:R-HSA-9630794|reactome:R-HSA-9632697|reactome:R-HSA-9632700|reactome:R-HSA-9661069 refseq:NP_001253.1|refseq:NP_523240.1|ensembl:ENSG00000123080(gene)|ensembl:ENST00000262662(transcript)|ensembl:ENST00000371761(transcript)|ensembl:ENST00000396148(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002110(Ankyrin)|interpro:IPR036770|mint:P42773|rcsb pdb:1BU9|rcsb pdb:1G3N|rcsb pdb:1IHB|rcsb pdb:1MX2|rcsb pdb:1MX4|rcsb pdb:1MX6|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-69231 - - comment:"author score: 188" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pxIzF9EkX+gMz7zj/TDiytYtsOc9606 rogid:Of2GgenNQNEF+WySg8SoGFBfYkE9606 rigid:IUSOYtSF6ODC9NJy2UixFM8FmqQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P11802 uniprotkb:P42771 intact:EBI-295644|uniprotkb:O00576|uniprotkb:Q6FG61|uniprotkb:B4DNF9|uniprotkb:B2R9A0|ensembl:ENSP00000257904 intact:EBI-375053|uniprotkb:O95440|uniprotkb:Q15191|uniprotkb:Q5VVJ5|uniprotkb:Q96B52|uniprotkb:Q9NP05|uniprotkb:A5X2G7|ensembl:ENSP00000307101|uniprotkb:D3DRK1|intact:EBI-7576126|intact:MINT-1344330|uniprotkb:G3XAG3 psi-mi:cdk4_human(display_long)|uniprotkb:CDK4(gene name)|psi-mi:CDK4(display_short)|uniprotkb:Cell division protein kinase 4(gene name synonym)|uniprotkb:PSK-J3(gene name synonym) psi-mi:cdn2a_human(display_long)|uniprotkb:CDKN2A(gene name)|psi-mi:CDKN2A(display_short)|uniprotkb:CDKN2(gene name synonym)|uniprotkb:Cyclin-dependent kinase 4 inhibitor A(gene name synonym)|uniprotkb:p16-INK4a(gene name synonym)|uniprotkb:Multiple tumor suppressor 1(gene name synonym)|uniprotkb:MTS1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477405|imex:IM-26985-309 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000066.1|dip:DIP-875N|ensembl:ENSG00000135446(gene)|ensembl:ENST00000257904(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000785"(chromatin)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0030332"(cyclin binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033574"(response to testosterone)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042493"|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046890"(regulation of lipid biosynthetic process)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050994"(regulation of lipid catabolic process)|go:"GO:0051301"(cell division)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060260"(regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060612"(adipose tissue development)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0097129"(cyclin D2-CDK4 complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904628"(cellular response to phorbol 13-acetate 12-myristate)|go:"GO:1904637"(cellular response to ionomycin)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P11802|rcsb pdb:1LD2|rcsb pdb:2W96|rcsb pdb:2W99|rcsb pdb:2W9F|rcsb pdb:2W9Z|rcsb pdb:3G33|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:6P8G|rcsb pdb:6P8H|reactome:R-HSA-187577|reactome:R-HSA-2559580|rcsb pdb:6P8E|rcsb pdb:6P8F|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-3214858|reactome:R-HSA-381340|reactome:R-HSA-69231|reactome:R-HSA-75815|reactome:R-HSA-8849470|reactome:R-HSA-8878166|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9630791|reactome:R-HSA-9630794|reactome:R-HSA-9632697|reactome:R-HSA-9632700|reactome:R-HSA-9661069 refseq:NP_000068.1|refseq:NP_478104.2|refseq:XP_011515981.1|ensembl:ENSG00000147889(gene)|ensembl:ENST00000304494(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0003723"(RNA binding)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090398"(cellular senescence)|go:"GO:0090399"(replicative senescence)|go:"GO:2000111"(positive regulation of macrophage apoptotic process)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR036770|mint:P42771|rcsb pdb:1A5E|rcsb pdb:1BI7|rcsb pdb:1DC2|rcsb pdb:2A5E|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-69231|reactome:R-HSA-8853884|reactome:R-HSA-9630791|reactome:R-HSA-9630794|reactome:R-HSA-9632697|reactome:R-HSA-9632700|refseq:NP_001182061.1|refseq:XP_005251400.1|dip:DIP-6108N - - comment:"author score: 253" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pxIzF9EkX+gMz7zj/TDiytYtsOc9606 rogid:9qd+YTVorW7jBQB23jJuOuMUKCk9606 rigid:IUSOYtSF6ODC9NJy2UixFM8FmqQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13112 uniprotkb:Q8TDI0 intact:EBI-1052944|uniprotkb:Q99548|ensembl:ENSP00000315700 intact:EBI-1042816|uniprotkb:O75032|uniprotkb:Q5TG89|uniprotkb:Q9UFR9|uniprotkb:Q7LGH2|intact:EBI-28978813|ensembl:ENSP00000262450 psi-mi:caf1b_human(display_long)|uniprotkb:Chromatin assembly factor I p60 subunit(gene name synonym)|uniprotkb:M-phase phosphoprotein 7(gene name synonym)|uniprotkb:CHAF1B(gene name)|psi-mi:CHAF1B(display_short)|uniprotkb:CAF1A(gene name synonym)|uniprotkb:CAF1P60(gene name synonym)|uniprotkb:MPHOSPH7(gene name synonym)|uniprotkb:MPP7(gene name synonym) psi-mi:chd5_human(display_long)|uniprotkb:CHD5(gene name)|psi-mi:CHD5(display_short)|uniprotkb:KIAA0444(gene name synonym)|uniprotkb:ATP-dependent helicase CHD5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477607|imex:IM-26985-155 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005432.1|dip:DIP-29243N|ensembl:ENSG00000159259(gene)|ensembl:ENST00000314103(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR029129|interpro:IPR036322|mint:Q13112|refseq:XP_016883966.1|refseq:XP_016883967.1 ensembl:ENSP00000262450|refseq:NP_056372.1|ensembl:ENSG00000116254(gene)|ensembl:ENST00000262450(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016581"(NuRD complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0035093"(spermatogenesis, exchange of chromosomal proteins)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0061628"(H3K27me3 modified histone binding)|go:"GO:0070615"|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|interpro:IPR000330(SNF2-related)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR028727|interpro:IPR038718|mint:Q8TDI0|rcsb pdb:6GUU - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:VVbW9mpUGYMRPxvlEk9FERHIsJs9606 rogid:LHBjWFoo0asvv1GpRsGBz1gN9gM9606 rigid:ScrplbJwVfC3kTV9NOarJKjgHqk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13112 uniprotkb:P68431 intact:EBI-1052944|uniprotkb:Q99548|ensembl:ENSP00000315700 intact:EBI-79722|ensembl:ENSP00000352252|ensembl:ENSP00000358160|ensembl:ENSP00000366999|ensembl:ENSP00000480826|ensembl:ENSP00000482271|ensembl:ENSP00000483283|ensembl:ENSP00000484095|ensembl:ENSP00000484638|ensembl:ENSP00000484658|ensembl:ENSP00000484841|ensembl:ENSP00000489282|intact:EBI-1560041|uniprotkb:A0PJT7|uniprotkb:P02295|uniprotkb:P02296|uniprotkb:P16106|uniprotkb:Q6ISV8|uniprotkb:Q6NWP8|uniprotkb:Q6NWP9|uniprotkb:Q6NXU4|uniprotkb:Q71DJ3|uniprotkb:Q93081|uniprotkb:A5PLR1 psi-mi:caf1b_human(display_long)|uniprotkb:Chromatin assembly factor I p60 subunit(gene name synonym)|uniprotkb:M-phase phosphoprotein 7(gene name synonym)|uniprotkb:CHAF1B(gene name)|psi-mi:CHAF1B(display_short)|uniprotkb:CAF1A(gene name synonym)|uniprotkb:CAF1P60(gene name synonym)|uniprotkb:MPHOSPH7(gene name synonym)|uniprotkb:MPP7(gene name synonym) psi-mi:h31_human(display_long)|uniprotkb:H3FA(gene name synonym)|uniprotkb:H3FL(gene name synonym)|uniprotkb:H3FD(gene name synonym)|uniprotkb:H3FI(gene name synonym)|uniprotkb:H3FH(gene name synonym)|uniprotkb:H3FK(gene name synonym)|uniprotkb:H3FF(gene name synonym)|uniprotkb:H3FJ(gene name synonym)|uniprotkb:H3FB(gene name synonym)|uniprotkb:Histone H3/a(gene name synonym)|uniprotkb:Histone H3/b(gene name synonym)|uniprotkb:Histone H3/c(gene name synonym)|uniprotkb:Histone H3/d(gene name synonym)|uniprotkb:Histone H3/f(gene name synonym)|uniprotkb:Histone H3/h(gene name synonym)|uniprotkb:Histone H3/i(gene name synonym)|uniprotkb:Histone H3/j(gene name synonym)|uniprotkb:Histone H3/k(gene name synonym)|uniprotkb:Histone H3/l(gene name synonym)|uniprotkb:H3C1(gene name)|psi-mi:H3C1(display_short)|uniprotkb:HIST1H3A(gene name synonym)|uniprotkb:H3C2(gene name)|psi-mi:H3C2(display_short)|uniprotkb:HIST1H3B(gene name synonym)|uniprotkb:H3C3(gene name)|psi-mi:H3C3(display_short)|uniprotkb:H3FC HIST1H3C(gene name synonym)|uniprotkb:H3C4(gene name)|psi-mi:H3C4(display_short)|uniprotkb:HIST1H3D(gene name synonym)|uniprotkb:H3C6(gene name)|psi-mi:H3C6(display_short)|uniprotkb:HIST1H3E(gene name synonym)|uniprotkb:H3C7(gene name)|psi-mi:H3C7(display_short)|uniprotkb:HIST1H3F(gene name synonym)|uniprotkb:H3C8(gene name)|psi-mi:H3C8(display_short)|uniprotkb:HIST1H3G(gene name synonym)|uniprotkb:H3C10(gene name)|psi-mi:H3C10(display_short)|uniprotkb:HIST1H3H(gene name synonym)|uniprotkb:H3C11(gene name)|psi-mi:H3C11(display_short)|uniprotkb:HIST1H3I(gene name synonym)|uniprotkb:H3C12(gene name)|psi-mi:H3C12(display_short)|uniprotkb:HIST1H3J(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477607|imex:IM-26985-155 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005432.1|dip:DIP-29243N|ensembl:ENSG00000159259(gene)|ensembl:ENST00000314103(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR029129|interpro:IPR036322|mint:Q13112|refseq:XP_016883966.1|refseq:XP_016883967.1 rcsb pdb:4TN7|rcsb pdb:4U68|rcsb pdb:4UP0|rcsb pdb:4UY4|rcsb pdb:4X3K|rcsb pdb:4Y6L|rcsb pdb:4YHP|rcsb pdb:4YHZ|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z0R|rcsb pdb:4Z2M|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:4QBS|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B31|rcsb pdb:5C11|rcsb pdb:5C13|rcsb pdb:5C3I|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5D6Y|rcsb pdb:5DAH|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5FFV|rcsb pdb:5GH9|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5H6Q|rcsb pdb:5H6R|rcsb pdb:5HJB|rcsb pdb:5HJC|rcsb pdb:5HJD|rcsb pdb:5HYN|rcsb pdb:5IQL|rcsb pdb:5J3V|rcsb pdb:5J9S|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5B2J|rcsb pdb:5JRG|rcsb pdb:5KJH|rcsb pdb:5KJI|rcsb pdb:5KKL|rcsb pdb:5LUG|rcsb pdb:5M5G|rcsb pdb:5MR8|rcsb pdb:5NNC|rcsb pdb:5OY3|rcsb pdb:5SVX|rcsb pdb:5SVY|rcsb pdb:5SZB|rcsb pdb:5SZC|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5T1G|rcsb pdb:5T1I|rcsb pdb:5T8R|rcsb pdb:5TBN|rcsb pdb:5TDR|rcsb pdb:5TDW|rcsb pdb:5U2J|rcsb pdb:5V21|rcsb pdb:5V22|rcsb pdb:5VA6|rcsb pdb:5VAB|rcsb pdb:5VGE|rcsb pdb:5VNB|rcsb pdb:5NND|rcsb pdb:5WLE|rcsb pdb:5WVO|rcsb pdb:5WXG|rcsb pdb:5WXH|rcsb pdb:5WYI|rcsb pdb:5X60|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5XFQ|rcsb pdb:5XFR|rcsb pdb:5XNV|rcsb pdb:5XTZ|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Y20|rcsb pdb:5Y2F|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:6AXJ|rcsb pdb:6AZE|rcsb pdb:6BHD|rcsb pdb:6BHE|rcsb pdb:6BHG|rcsb pdb:6BHH|rcsb pdb:6BHI|rcsb pdb:6D07|rcsb pdb:6D08|rcsb pdb:6E83|rcsb pdb:6E86|rcsb pdb:5WFC|rcsb pdb:6F6D|rcsb pdb:6HTS|rcsb pdb:6IEU|rcsb pdb:6IIS|rcsb pdb:6IIT|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6JXD|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6LS6|rcsb pdb:6LSD|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MIL|rcsb pdb:6MIM|rcsb pdb:6MIN|rcsb pdb:6MIO|rcsb pdb:6MIQ|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6HKT|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2H|rcsb pdb:6V2K|rcsb pdb:6V3N|rcsb pdb:6V41|rcsb pdb:6V92|rcsb pdb:6VIL|rcsb pdb:6WAV|rcsb pdb:6WW4|rcsb pdb:6YIF|rcsb pdb:6YIH|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:6R92|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7KLR|rcsb pdb:7LYC|reactome:R-HSA-1266695|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|ensembl:ENSG00000197153(gene)|ensembl:ENSG00000197409(gene)|ensembl:ENSG00000273983(gene)|ensembl:ENSG00000274750(gene)|ensembl:ENSG00000275379(gene)|ensembl:ENSG00000275714(gene)|ensembl:ENSG00000277775(gene)|ensembl:ENSG00000278828(gene)|ensembl:ENSG00000286522(gene)|ensembl:ENSG00000287080(gene)|ensembl:ENST00000356476(transcript)|ensembl:ENST00000359303(transcript)|ensembl:ENST00000369163(transcript)|ensembl:ENST00000612966(transcript)|ensembl:ENST00000613854(transcript)|ensembl:ENST00000614378(transcript)|ensembl:ENST00000614911(transcript)|ensembl:ENST00000616365(transcript)|ensembl:ENST00000618052(transcript)|ensembl:ENST00000621411(transcript)|ensembl:ENST00000634733(transcript)|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-3247509|reactome:R-HSA-9710421|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060968"(obsolete regulation of gene silencing)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|interpro:IPR009072(Histone-fold)|mint:P68431|rcsb pdb:1CS9|rcsb pdb:1CT6|rcsb pdb:1O9S|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|rcsb pdb:1Q3L|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|rcsb pdb:2B2T|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|rcsb pdb:2B2U|rcsb pdb:2B2V|rcsb pdb:2B2W|rcsb pdb:2C1J|rcsb pdb:2C1N|go:"GO:0016020"(membrane)|rcsb pdb:2CO0|rcsb pdb:2CV5|rcsb pdb:2FSA|rcsb pdb:2KWJ|rcsb pdb:2KWK|rcsb pdb:2L75|rcsb pdb:2LBM|rcsb pdb:2LGG|rcsb pdb:2M0O|reactome:R-HSA-983231|reactome:R-HSA-977225|rcsb pdb:2NDG|rcsb pdb:2OQ6|rcsb pdb:2OT7|rcsb pdb:2OX0|rcsb pdb:2RI7|rcsb pdb:2RR4|rcsb pdb:2UXN|rcsb pdb:2V85|rcsb pdb:2V89|rcsb pdb:2VNF|rcsb pdb:2VPG|rcsb pdb:2X0L|rcsb pdb:3A1B|rcsb pdb:2NDF|rcsb pdb:3AFA|rcsb pdb:3AVR|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3B95|rcsb pdb:3FDT|rcsb pdb:3KMT|rcsb pdb:3KQI|rcsb pdb:3LQI|rcsb pdb:3LQJ|rcsb pdb:3MP1|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O37|rcsb pdb:3QJ6|rcsb pdb:3RIG|rcsb pdb:3RIY|rcsb pdb:3SOU|rcsb pdb:3SOW|rcsb pdb:3U31|rcsb pdb:3U3D|rcsb pdb:3U4S|rcsb pdb:3U5N|rcsb pdb:3U5O|rcsb pdb:3AZK|rcsb pdb:3U5P|rcsb pdb:3UEE|rcsb pdb:3UEF|rcsb pdb:3UII|rcsb pdb:3UIK|rcsb pdb:3V43|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:3ZG6|rcsb pdb:3ZVY|rcsb pdb:4A0J|rcsb pdb:4A0N|rcsb pdb:4A7J|rcsb pdb:3UIG|rcsb pdb:4BD3|rcsb pdb:4C1Q|rcsb pdb:4F4U|rcsb pdb:4F56|rcsb pdb:4FWF|rcsb pdb:4HON|rcsb pdb:4I51|rcsb pdb:4L7X|rcsb pdb:4LK9|rcsb pdb:4LKA|rcsb pdb:4LLB|rcsb pdb:4LXL|rcsb pdb:4N4H|rcsb pdb:4QBQ|rcsb pdb:4QBR|refseq:NP_003520.1|refseq:NP_003521.2|refseq:NP_003522.1|refseq:NP_003523.1|refseq:NP_003524.1|refseq:NP_003525.1|refseq:NP_003526.1|refseq:NP_003527.1|refseq:NP_003528.1|refseq:NP_066298.1|dip:DIP-29371N - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:VVbW9mpUGYMRPxvlEk9FERHIsJs9606 rogid:ood0OohxZHuhsWZtO7U7GMc+LwM9606 rigid:ScrplbJwVfC3kTV9NOarJKjgHqk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13112 uniprotkb:P62805 intact:EBI-1052944|uniprotkb:Q99548|ensembl:ENSP00000315700 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:caf1b_human(display_long)|uniprotkb:Chromatin assembly factor I p60 subunit(gene name synonym)|uniprotkb:M-phase phosphoprotein 7(gene name synonym)|uniprotkb:CHAF1B(gene name)|psi-mi:CHAF1B(display_short)|uniprotkb:CAF1A(gene name synonym)|uniprotkb:CAF1P60(gene name synonym)|uniprotkb:MPHOSPH7(gene name synonym)|uniprotkb:MPP7(gene name synonym) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477607|imex:IM-26985-155 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005432.1|dip:DIP-29243N|ensembl:ENSG00000159259(gene)|ensembl:ENST00000314103(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR029129|interpro:IPR036322|mint:Q13112|refseq:XP_016883966.1|refseq:XP_016883967.1 ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:VVbW9mpUGYMRPxvlEk9FERHIsJs9606 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 rigid:ScrplbJwVfC3kTV9NOarJKjgHqk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13112 uniprotkb:Q8WXX5 intact:EBI-1052944|uniprotkb:Q99548|ensembl:ENSP00000315700 intact:EBI-2349100|uniprotkb:B2RMW6|ensembl:ENSP00000362041 psi-mi:caf1b_human(display_long)|uniprotkb:Chromatin assembly factor I p60 subunit(gene name synonym)|uniprotkb:M-phase phosphoprotein 7(gene name synonym)|uniprotkb:CHAF1B(gene name)|psi-mi:CHAF1B(display_short)|uniprotkb:CAF1A(gene name synonym)|uniprotkb:CAF1P60(gene name synonym)|uniprotkb:MPHOSPH7(gene name synonym)|uniprotkb:MPP7(gene name synonym) psi-mi:dnjc9_human(display_long)|uniprotkb:DNAJC9(gene name)|psi-mi:DNAJC9(display_short)|uniprotkb:DnaJ protein SB73(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477607|imex:IM-26985-155 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005432.1|dip:DIP-29243N|ensembl:ENSG00000159259(gene)|ensembl:ENST00000314103(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR029129|interpro:IPR036322|mint:Q13112|refseq:XP_016883966.1|refseq:XP_016883967.1 refseq:NP_056005.1|ensembl:ENSG00000213551(gene)|ensembl:ENST00000372950(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:Q8WXX5|rcsb pdb:7CIZ|rcsb pdb:7CJ0|go:"GO:0005829"(cytosol) - - comment:"author score: 33" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:VVbW9mpUGYMRPxvlEk9FERHIsJs9606 rogid:K1fhi/D2XXu0PXipEvxGKWyDMMI9606 rigid:ScrplbJwVfC3kTV9NOarJKjgHqk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13112 uniprotkb:Q09028 intact:EBI-1052944|uniprotkb:Q99548|ensembl:ENSP00000315700 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 psi-mi:caf1b_human(display_long)|uniprotkb:Chromatin assembly factor I p60 subunit(gene name synonym)|uniprotkb:M-phase phosphoprotein 7(gene name synonym)|uniprotkb:CHAF1B(gene name)|psi-mi:CHAF1B(display_short)|uniprotkb:CAF1A(gene name synonym)|uniprotkb:CAF1P60(gene name synonym)|uniprotkb:MPHOSPH7(gene name synonym)|uniprotkb:MPP7(gene name synonym) psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477607|imex:IM-26985-155 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005432.1|dip:DIP-29243N|ensembl:ENSG00000159259(gene)|ensembl:ENST00000314103(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR029129|interpro:IPR036322|mint:Q13112|refseq:XP_016883966.1|refseq:XP_016883967.1 ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N - - comment:"author score: 51" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:VVbW9mpUGYMRPxvlEk9FERHIsJs9606 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rigid:ScrplbJwVfC3kTV9NOarJKjgHqk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13112 uniprotkb:Q13111 intact:EBI-1052944|uniprotkb:Q99548|ensembl:ENSP00000315700 intact:EBI-1020839|uniprotkb:Q7Z7K3|uniprotkb:Q9UJY8|uniprotkb:Q6NXG5|intact:EBI-28985893|ensembl:ENSP00000301280 psi-mi:caf1b_human(display_long)|uniprotkb:Chromatin assembly factor I p60 subunit(gene name synonym)|uniprotkb:M-phase phosphoprotein 7(gene name synonym)|uniprotkb:CHAF1B(gene name)|psi-mi:CHAF1B(display_short)|uniprotkb:CAF1A(gene name synonym)|uniprotkb:CAF1P60(gene name synonym)|uniprotkb:MPHOSPH7(gene name synonym)|uniprotkb:MPP7(gene name synonym) psi-mi:caf1a_human(display_long)|uniprotkb:CHAF1A(gene name)|psi-mi:CHAF1A(display_short)|uniprotkb:CAF(gene name synonym)|uniprotkb:CAF1P150(gene name synonym)|uniprotkb:Chromatin assembly factor I p150 subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477607|imex:IM-26985-155 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005432.1|dip:DIP-29243N|ensembl:ENSG00000159259(gene)|ensembl:ENST00000314103(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR029129|interpro:IPR036322|mint:Q13112|refseq:XP_016883966.1|refseq:XP_016883967.1 refseq:NP_005474.2|ensembl:ENSG00000167670(gene)|ensembl:ENST00000301280(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070087"(chromo shadow domain binding)|interpro:IPR022043|interpro:IPR029091|interpro:IPR029105|mint:Q13111|ensembl:ENSP00000301280|dip:DIP-31135N - - comment:"author score: 117" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:VVbW9mpUGYMRPxvlEk9FERHIsJs9606 rogid:8ZlQPVvmtN638aK8ZblErN5Bhjo9606 rigid:ScrplbJwVfC3kTV9NOarJKjgHqk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UEE9 uniprotkb:P04908 intact:EBI-747834|uniprotkb:O00393|uniprotkb:O00404|uniprotkb:Q9UEF0|uniprotkb:Q9UEF1|uniprotkb:Q9UEF8|ensembl:ENSP00000283882 intact:EBI-358971|uniprotkb:Q76P63|uniprotkb:P28001|ensembl:ENSP00000303373|ensembl:ENSP00000483842 psi-mi:cfdp1_human(display_long)|uniprotkb:Bucentaur(gene name synonym)|uniprotkb:CFDP1(gene name)|psi-mi:CFDP1(display_short)|uniprotkb:BCNT(gene name synonym)|uniprotkb:CENP-29(gene name synonym) psi-mi:h2a1b_human(display_long)|uniprotkb:H2AC4(gene name)|psi-mi:H2AC4(display_short)|uniprotkb:H2AC8(gene name)|psi-mi:H2AC8(display_short)|uniprotkb:H2AFA(gene name synonym)|uniprotkb:H2AFM(gene name synonym)|uniprotkb:HIST1H2AB(gene name synonym)|uniprotkb:HIST1H2AE(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/a(gene name synonym)|uniprotkb:Histone H2A/m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477571|imex:IM-26985-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006315.1|ensembl:ENSG00000153774(gene)|ensembl:ENST00000283882(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0007155"(cell adhesion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:2000270"(negative regulation of fibroblast apoptotic process)|interpro:IPR011421(Bucentaur or craniofacial development)|interpro:IPR027124|mint:Q9UEE9 refseq:NP_003504.2|refseq:NP_066390.1|ensembl:ENSG00000277075(gene)|ensembl:ENSG00000278463(gene)|ensembl:ENST00000303910(transcript)|ensembl:ENST00000615868(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P04908|rcsb pdb:2CV5|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1V|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACL|rcsb pdb:6AEE|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6KE9|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V92|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|rcsb pdb:6JXD|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|dip:DIP-44197N - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RlxghkvgEkMZXgoX9ZXzSAnrrZE9606 rogid:4Qno1mMYZB6FdNoojrzulWLVq849606 rigid:sSuIrBvjHJPamC9TdK/5fPfSH0E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UEE9 uniprotkb:Q9NZT1 intact:EBI-747834|uniprotkb:O00393|uniprotkb:O00404|uniprotkb:Q9UEF0|uniprotkb:Q9UEF1|uniprotkb:Q9UEF8|ensembl:ENSP00000283882 intact:EBI-1051681|uniprotkb:Q8IXU8|uniprotkb:Q5SQI3|ensembl:ENSP00000369689 psi-mi:cfdp1_human(display_long)|uniprotkb:Bucentaur(gene name synonym)|uniprotkb:CFDP1(gene name)|psi-mi:CFDP1(display_short)|uniprotkb:BCNT(gene name synonym)|uniprotkb:CENP-29(gene name synonym) psi-mi:call5_human(display_long)|uniprotkb:Calmodulin-like skin protein(gene name synonym)|uniprotkb:CALML5(gene name)|psi-mi:CALML5(display_short)|uniprotkb:CLSP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477571|imex:IM-26985-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006315.1|ensembl:ENSG00000153774(gene)|ensembl:ENST00000283882(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0007155"(cell adhesion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:2000270"(negative regulation of fibroblast apoptotic process)|interpro:IPR011421(Bucentaur or craniofacial development)|interpro:IPR027124|mint:Q9UEE9 refseq:NP_059118.2|ensembl:ENST00000380332(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007165"(signal transduction)|go:"GO:0008544"(epidermis development)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q9NZT1|rcsb pdb:2B1U|reactome:R-HSA-6798695|ensembl:ENSG00000178372(gene) - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RlxghkvgEkMZXgoX9ZXzSAnrrZE9606 rogid:uPD/avsoqpiogqHCK5TGJQwvCX89606 rigid:sSuIrBvjHJPamC9TdK/5fPfSH0E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UEE9 uniprotkb:P40939 intact:EBI-747834|uniprotkb:O00393|uniprotkb:O00404|uniprotkb:Q9UEF0|uniprotkb:Q9UEF1|uniprotkb:Q9UEF8|ensembl:ENSP00000283882 intact:EBI-356720|uniprotkb:Q16679|uniprotkb:Q96GT7|uniprotkb:B2R7L4|uniprotkb:B4DYP2|uniprotkb:Q9UQC5|ensembl:ENSP00000370023|uniprotkb:Q53T69|uniprotkb:Q53TA2 psi-mi:cfdp1_human(display_long)|uniprotkb:Bucentaur(gene name synonym)|uniprotkb:CFDP1(gene name)|psi-mi:CFDP1(display_short)|uniprotkb:BCNT(gene name synonym)|uniprotkb:CENP-29(gene name synonym) psi-mi:echa_human(display_long)|uniprotkb:HADHA(gene name)|psi-mi:HADHA(display_short)|uniprotkb:HADH(gene name synonym)|uniprotkb:TP-alpha(gene name synonym)|uniprotkb:78 kDa gastrin-binding protein(gene name synonym)|uniprotkb:Monolysocardiolipin acyltransferase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477571|imex:IM-26985-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006315.1|ensembl:ENSG00000153774(gene)|ensembl:ENST00000283882(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0007155"(cell adhesion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:2000270"(negative regulation of fibroblast apoptotic process)|interpro:IPR011421(Bucentaur or craniofacial development)|interpro:IPR027124|mint:Q9UEE9 refseq:NP_000173.2|ensembl:ENSG00000084754(gene)|ensembl:ENST00000380649(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0003985"(acetyl-CoA C-acetyltransferase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016507"(mitochondrial fatty acid beta-oxidation multienzyme complex)|go:"GO:0016508"(long-chain-enoyl-CoA hydratase activity)|go:"GO:0016509"(long-chain-3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0035965"(cardiolipin acyl-chain remodeling)|go:"GO:0042493"|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0070403"(NAD+ binding)|interpro:IPR001753(Crotonase, core)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR012803(Fatty acid oxidation complex, alpha subunit, mitochondrial)|interpro:IPR018376|interpro:IPR029045|interpro:IPR036291|mint:P40939|rcsb pdb:5ZQZ|rcsb pdb:5ZRV|rcsb pdb:6DV2|reactome:R-HSA-1482798|reactome:R-HSA-77285|reactome:R-HSA-77288|reactome:R-HSA-77305|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|reactome:R-HSA-77350 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RlxghkvgEkMZXgoX9ZXzSAnrrZE9606 rogid:Dr5HQoO5+a+6Q9OtvDIhM4yw4Cg9606 rigid:sSuIrBvjHJPamC9TdK/5fPfSH0E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UEE9 uniprotkb:P55084 intact:EBI-747834|uniprotkb:O00393|uniprotkb:O00404|uniprotkb:Q9UEF0|uniprotkb:Q9UEF1|uniprotkb:Q9UEF8|ensembl:ENSP00000283882 intact:EBI-356635|uniprotkb:Q9T2V8|uniprotkb:O14969|uniprotkb:Q53TA6|uniprotkb:Q96C77|uniprotkb:Q9H3F5|uniprotkb:B2RB16|intact:EBI-2948478|ensembl:ENSP00000325136|intact:EBI-8012123|intact:MINT-8395035|uniprotkb:B4E2W0 psi-mi:cfdp1_human(display_long)|uniprotkb:Bucentaur(gene name synonym)|uniprotkb:CFDP1(gene name)|psi-mi:CFDP1(display_short)|uniprotkb:BCNT(gene name synonym)|uniprotkb:CENP-29(gene name synonym) psi-mi:echb_human(display_long)|uniprotkb:HADHB(gene name)|psi-mi:HADHB(display_short)|uniprotkb:MSTP029(orf name)|uniprotkb:TP-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477571|imex:IM-26985-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006315.1|ensembl:ENSG00000153774(gene)|ensembl:ENST00000283882(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0007155"(cell adhesion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:2000270"(negative regulation of fibroblast apoptotic process)|interpro:IPR011421(Bucentaur or craniofacial development)|interpro:IPR027124|mint:Q9UEE9 refseq:NP_000174.1|ensembl:ENSG00000138029(gene)|ensembl:ENST00000317799(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005740"(mitochondrial envelope)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0050633"(acetyl-CoA C-myristoyltransferase activity)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|mint:P55084|rcsb pdb:5ZQZ|rcsb pdb:5ZRV|rcsb pdb:6DV2|reactome:R-HSA-1482798|reactome:R-HSA-77285|reactome:R-HSA-77288|reactome:R-HSA-77305|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|reactome:R-HSA-77350|refseq:XP_011531105.1|refseq:NP_001268441.1|refseq:NP_001268442.1 - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RlxghkvgEkMZXgoX9ZXzSAnrrZE9606 rogid:4w0QYaw1wLyr5NJOKZ9naymK8kg9606 rigid:sSuIrBvjHJPamC9TdK/5fPfSH0E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UEE9 uniprotkb:Q8IUE6 intact:EBI-747834|uniprotkb:O00393|uniprotkb:O00404|uniprotkb:Q9UEF0|uniprotkb:Q9UEF1|uniprotkb:Q9UEF8|ensembl:ENSP00000283882 intact:EBI-1642157|ensembl:ENSP00000332790 psi-mi:cfdp1_human(display_long)|uniprotkb:Bucentaur(gene name synonym)|uniprotkb:CFDP1(gene name)|psi-mi:CFDP1(display_short)|uniprotkb:BCNT(gene name synonym)|uniprotkb:CENP-29(gene name synonym) psi-mi:h2a2b_human(display_long)|uniprotkb:H2AC21(gene name)|psi-mi:H2AC21(display_short)|uniprotkb:H2A-clustered histone 21(gene name synonym)|uniprotkb:HIST2H2AB(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477571|imex:IM-26985-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006315.1|ensembl:ENSG00000153774(gene)|ensembl:ENST00000283882(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0007155"(cell adhesion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:2000270"(negative regulation of fibroblast apoptotic process)|interpro:IPR011421(Bucentaur or craniofacial development)|interpro:IPR027124|mint:Q9UEE9 refseq:NP_778235.1|ensembl:ENSG00000184270(gene)|ensembl:ENST00000331128(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:Q8IUE6|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - comment:"author score: 37" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RlxghkvgEkMZXgoX9ZXzSAnrrZE9606 rogid:1F8W3E3hVpwLzJsW/37w8XshfOE9606 rigid:sSuIrBvjHJPamC9TdK/5fPfSH0E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UEE9 uniprotkb:Q9UQE7 intact:EBI-747834|uniprotkb:O00393|uniprotkb:O00404|uniprotkb:Q9UEF0|uniprotkb:Q9UEF1|uniprotkb:Q9UEF8|ensembl:ENSP00000283882 intact:EBI-80718|ensembl:ENSP00000354720|uniprotkb:O60464|uniprotkb:Q5T482|uniprotkb:A8K156 psi-mi:cfdp1_human(display_long)|uniprotkb:Bucentaur(gene name synonym)|uniprotkb:CFDP1(gene name)|psi-mi:CFDP1(display_short)|uniprotkb:BCNT(gene name synonym)|uniprotkb:CENP-29(gene name synonym) psi-mi:smc3_human(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:BAM(gene name synonym)|uniprotkb:SMC3L1(gene name synonym)|uniprotkb:Chondroitin sulfate proteoglycan 6(gene name synonym)|uniprotkb:Chromosome-associated polypeptide(gene name synonym)|uniprotkb:Basement membrane-associated chondroitin proteoglycan(gene name synonym)|uniprotkb:BMH(gene name synonym)|uniprotkb:CSPG6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477571|imex:IM-26985-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006315.1|ensembl:ENSG00000153774(gene)|ensembl:ENST00000283882(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0007155"(cell adhesion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:2000270"(negative regulation of fibroblast apoptotic process)|interpro:IPR011421(Bucentaur or craniofacial development)|interpro:IPR027124|mint:Q9UEE9 go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|mint:Q9UQE7|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0070840"(dynein complex binding)|ensembl:ENSG00000108055(gene)|ensembl:ENST00000361804(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|refseq:NP_005436.1|dip:DIP-29200N - - comment:"author score: 38" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RlxghkvgEkMZXgoX9ZXzSAnrrZE9606 rogid:pUxr+sTtttRzGlqCRz/25woNtrg9606 rigid:sSuIrBvjHJPamC9TdK/5fPfSH0E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UEE9 uniprotkb:Q14683 intact:EBI-747834|uniprotkb:O00393|uniprotkb:O00404|uniprotkb:Q9UEF0|uniprotkb:Q9UEF1|uniprotkb:Q9UEF8|ensembl:ENSP00000283882 intact:EBI-80690|ensembl:ENSP00000323421|uniprotkb:O14995|uniprotkb:Q16351|uniprotkb:Q2M228 psi-mi:cfdp1_human(display_long)|uniprotkb:Bucentaur(gene name synonym)|uniprotkb:CFDP1(gene name)|psi-mi:CFDP1(display_short)|uniprotkb:BCNT(gene name synonym)|uniprotkb:CENP-29(gene name synonym) psi-mi:smc1a_human(display_long)|uniprotkb:SMC1A(gene name)|psi-mi:SMC1A(display_short)|uniprotkb:DXS423E(gene name synonym)|uniprotkb:KIAA0178(gene name synonym)|uniprotkb:SB1.8(gene name synonym)|uniprotkb:SMC1(gene name synonym)|uniprotkb:SMC1L1(gene name synonym)|uniprotkb:Sb1.8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477571|imex:IM-26985-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006315.1|ensembl:ENSG00000153774(gene)|ensembl:ENST00000283882(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0007155"(cell adhesion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:2000270"(negative regulation of fibroblast apoptotic process)|interpro:IPR011421(Bucentaur or craniofacial development)|interpro:IPR027124|mint:Q9UEE9 ensembl:ENSG00000072501(gene)|ensembl:ENST00000322213(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0009314"(response to radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR029683|interpro:IPR036277|mint:Q14683|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|reactome:R-HSA-2468052|refseq:NP_006297.2|dip:DIP-30911N - - comment:"author score: 45" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RlxghkvgEkMZXgoX9ZXzSAnrrZE9606 rogid:0UhfA7txIetlcGvSes6d+Bv1ZdY9606 rigid:sSuIrBvjHJPamC9TdK/5fPfSH0E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UEE9 uniprotkb:P06899 intact:EBI-747834|uniprotkb:O00393|uniprotkb:O00404|uniprotkb:Q9UEF0|uniprotkb:Q9UEF1|uniprotkb:Q9UEF8|ensembl:ENSP00000283882 intact:EBI-6150252|uniprotkb:B2R4J4|uniprotkb:O60816|ensembl:ENSP00000342886|ensembl:ENSP00000476136 psi-mi:cfdp1_human(display_long)|uniprotkb:Bucentaur(gene name synonym)|uniprotkb:CFDP1(gene name)|psi-mi:CFDP1(display_short)|uniprotkb:BCNT(gene name synonym)|uniprotkb:CENP-29(gene name synonym) psi-mi:h2b1j_human(display_long)|uniprotkb:H2BC11(gene name)|psi-mi:H2BC11(display_short)|uniprotkb:H2BFR(gene name synonym)|uniprotkb:HIST1H2BJ(gene name synonym)|uniprotkb:Histone H2B.1(gene name synonym)|uniprotkb:Histone H2B.r(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477571|imex:IM-26985-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006315.1|ensembl:ENSG00000153774(gene)|ensembl:ENST00000283882(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0007155"(cell adhesion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:2000270"(negative regulation of fibroblast apoptotic process)|interpro:IPR011421(Bucentaur or craniofacial development)|interpro:IPR027124|mint:Q9UEE9 refseq:NP_066402.2|dip:DIP-421N|ensembl:ENSG00000124635(gene)|ensembl:ENST00000339812(transcript)|ensembl:ENST00000607124(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P06899|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WAA|rcsb pdb:3WTP|rcsb pdb:4CAY|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5FUG|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5VEY|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6JXD|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6YOV|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7K5X|rcsb pdb:3WA9|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - comment:"author score: 66" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RlxghkvgEkMZXgoX9ZXzSAnrrZE9606 rogid:74GQlSjGG1Ez6Uog74VXPLryKBc9606 rigid:sSuIrBvjHJPamC9TdK/5fPfSH0E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UEE9 uniprotkb:Q9UNP9 intact:EBI-747834|uniprotkb:O00393|uniprotkb:O00404|uniprotkb:Q9UEF0|uniprotkb:Q9UEF1|uniprotkb:Q9UEF8|ensembl:ENSP00000283882 intact:EBI-591818|uniprotkb:Q3S611|uniprotkb:Q5TGA3|uniprotkb:O43634|uniprotkb:O43635|uniprotkb:Q32Q72|uniprotkb:Q5TGA0|uniprotkb:Q5TGA2|uniprotkb:Q9UIZ5|uniprotkb:B2R971|ensembl:ENSP00000312769 psi-mi:cfdp1_human(display_long)|uniprotkb:Bucentaur(gene name synonym)|uniprotkb:CFDP1(gene name)|psi-mi:CFDP1(display_short)|uniprotkb:BCNT(gene name synonym)|uniprotkb:CENP-29(gene name synonym) psi-mi:ppie_human(display_long)|uniprotkb:Cyclophilin E(gene name synonym)|uniprotkb:Cyclophilin-33(gene name synonym)|uniprotkb:PPIE(gene name)|psi-mi:PPIE(display_short)|uniprotkb:CYP33(gene name synonym)|uniprotkb:Rotamase E(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477571|imex:IM-26985-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006315.1|ensembl:ENSG00000153774(gene)|ensembl:ENST00000283882(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0007155"(cell adhesion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:2000270"(negative regulation of fibroblast apoptotic process)|interpro:IPR011421(Bucentaur or craniofacial development)|interpro:IPR027124|mint:Q9UEE9 refseq:NP_006103.1|refseq:NP_982281.1|refseq:NP_001181936.1|refseq:XP_016855540.1|dip:DIP-34757N|ensembl:ENSG00000084072(gene)|ensembl:ENST00000324379(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR016304(Peptidyl-prolyl cis-trans isomerase E)|interpro:IPR020892|interpro:IPR029000|interpro:IPR034168|interpro:IPR035979|mint:Q9UNP9|rcsb pdb:1ZMF|rcsb pdb:2CQB|rcsb pdb:2KU7|rcsb pdb:2KYX|rcsb pdb:2R99|rcsb pdb:3LPY|rcsb pdb:3MDF|rcsb pdb:3UCH|rcsb pdb:5MQF|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6798695|reactome:R-HSA-72163 - - comment:"author score: 70" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RlxghkvgEkMZXgoX9ZXzSAnrrZE9606 rogid:zMkadgyIl5RwvoD3h3vetTqLjg49606 rigid:sSuIrBvjHJPamC9TdK/5fPfSH0E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UEE9 uniprotkb:O95072 intact:EBI-747834|uniprotkb:O00393|uniprotkb:O00404|uniprotkb:Q9UEF0|uniprotkb:Q9UEF1|uniprotkb:Q9UEF8|ensembl:ENSP00000283882 intact:EBI-9361206|uniprotkb:Q658V5|uniprotkb:Q6IA92|uniprotkb:D3DS62|uniprotkb:Q8WUV8|uniprotkb:A8K576|uniprotkb:Q9NVQ9|uniprotkb:Q9BTF2|ensembl:ENSP00000482439|ensembl:ENSP00000482546|ensembl:ENSP00000493523|ensembl:ENSP00000495458 psi-mi:cfdp1_human(display_long)|uniprotkb:Bucentaur(gene name synonym)|uniprotkb:CFDP1(gene name)|psi-mi:CFDP1(display_short)|uniprotkb:BCNT(gene name synonym)|uniprotkb:CENP-29(gene name synonym) psi-mi:rec8_human(display_long)|uniprotkb:REC8(gene name)|psi-mi:REC8(display_short)|uniprotkb:Cohesin Rec8p(gene name synonym)|uniprotkb:REC8L1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477571|imex:IM-26985-13 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006315.1|ensembl:ENSG00000153774(gene)|ensembl:ENST00000283882(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0007155"(cell adhesion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:2000270"(negative regulation of fibroblast apoptotic process)|interpro:IPR011421(Bucentaur or craniofacial development)|interpro:IPR027124|mint:Q9UEE9 refseq:NP_001041670.1|refseq:NP_005123.2|ensembl:ENSG00000100918(gene)|ensembl:ENSG00000285007(gene)|ensembl:ENST00000611366(transcript)|ensembl:ENST00000620473(transcript)|ensembl:ENST00000642486(transcript)|ensembl:ENST00000646765(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0009566"(fertilization)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|mint:O95072|reactome:R-HSA-1221632 - - comment:"author score: 71" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RlxghkvgEkMZXgoX9ZXzSAnrrZE9606 rogid:DQKOCe+CcQ6mDGL+8bpeW0PGbe49606 rigid:sSuIrBvjHJPamC9TdK/5fPfSH0E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43303 uniprotkb:Q8IW35 intact:EBI-1566217|uniprotkb:O43335|uniprotkb:Q68DV9|uniprotkb:Q8NE13|uniprotkb:B7WP23|ensembl:ENSP00000370803 intact:EBI-1566210|uniprotkb:Q8NA71|uniprotkb:Q9H5T9|uniprotkb:B5MDY8|intact:EBI-2560935|ensembl:ENSP00000342510 psi-mi:cp110_human(display_long)|uniprotkb:CP110(gene name synonym)|uniprotkb:CCP110(gene name)|psi-mi:CCP110(display_short)|uniprotkb:CEP110(gene name synonym)|uniprotkb:KIAA0419(gene name synonym)|uniprotkb:Centrosomal protein of 110 kDa(gene name synonym) psi-mi:cep97_human(display_long)|uniprotkb:LRRIQ2(gene name synonym)|uniprotkb:Leucine-rich repeat and IQ domain-containing protein 2(gene name synonym)|uniprotkb:CEP97(gene name)|psi-mi:CEP97(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25477562|imex:IM-26985-237 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001310498.1|refseq:NP_001185951.2|refseq:NP_001310499.1|refseq:NP_001310500.1|refseq:NP_001310501.1|refseq:NP_055526.4|refseq:XP_011544293.1|refseq:XP_011544294.1|refseq:XP_016879397.1|dip:DIP-39892N|ensembl:ENSG00000103540(gene)|ensembl:ENST00000381396(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0007099"(centriole replication)|go:"GO:0032053"(ciliary basal body organization)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045724"(positive regulation of cilium assembly)|go:"GO:0051298"(centrosome duplication)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1903723"(negative regulation of centriole elongation)|interpro:IPR033207|mint:O43303|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5689880|reactome:R-HSA-8854518|reactome:R-HSA-9013424 refseq:NP_078824.2|refseq:NP_001290330.1|ensembl:ENSG00000182504(gene)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0030030"(cell projection organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902018"(negative regulation of cilium assembly)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|mint:Q8IW35|reactome:R-HSA-5620912|reactome:R-HSA-9013424|ensembl:ENST00000341893(transcript) - comment:"author score: 13" - figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Gvda4RoDRcY+G50iRW5T+haubps9606 rogid:Gz4rQbzgNiEg1X01O7YWz4TmfQA9606 rigid:iBSQzb5qI4ocwXEdY/h+C5UgvZw false - tandem tag:n-n - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92674 uniprotkb:Q9BS16 intact:EBI-11085153|uniprotkb:Q96ED0|uniprotkb:Q5JWZ9|ensembl:ENSP00000362018|ensembl:ENSP00000507595|ensembl:ENSP00000507927 intact:EBI-6871750|ensembl:ENSP00000242872|ensembl:ENSP00000379911|ensembl:ENSP00000422421|uniprotkb:Q9H4L0 psi-mi:cenpi_human(display_long)|uniprotkb:CENPI(gene name)|psi-mi:CENPI(display_short)|uniprotkb:FSH primary response protein 1(gene name synonym)|uniprotkb:FSHPRH1(gene name synonym)|uniprotkb:Follicle-stimulating hormone primary response protein(gene name synonym)|uniprotkb:ICEN19(gene name synonym)|uniprotkb:Interphase centromere complex protein 19(gene name synonym)|uniprotkb:LRPR1(gene name synonym)|uniprotkb:Leucine-rich primary response protein 1(gene name synonym) psi-mi:cenpk_human(display_long)|uniprotkb:Protein AF-5alpha(gene name synonym)|uniprotkb:p33(gene name synonym)|uniprotkb:FKSG14(orf name)|uniprotkb:ICEN37(gene name synonym)|uniprotkb:Interphase centromere complex protein 37(gene name synonym)|uniprotkb:CENPK(gene name)|psi-mi:CENPK(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25477553|imex:IM-26985-535 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006724.2|refseq:XP_005262168.1|refseq:XP_011529196.1|refseq:XP_011529197.1|refseq:XP_011529199.1|refseq:XP_011529201.1|refseq:NP_001305452.1|ensembl:ENSG00000102384(gene)|ensembl:ENST00000372927(transcript)|ensembl:ENST00000682095(transcript)|ensembl:ENST00000684367(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007548"(sex differentiation)|go:"GO:0016604"(nuclear body)|go:"GO:0034508"(centromere complex assembly)|interpro:IPR012485(Mis6)|mint:Q92674|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-2500257 refseq:XP_011541838.1|refseq:XP_016865179.1|refseq:XP_016865180.1|refseq:XP_016865181.1|ensembl:ENSG00000123219(gene)|ensembl:ENST00000242872(transcript)|ensembl:ENST00000396679(transcript)|ensembl:ENST00000514814(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000939"(inner kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR020993|mint:Q9BS16|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001253967.1|refseq:NP_071428.2 - comment:"author score: 53" - figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:LQS7ERffOiJEX+FEMvhaHhak/qw9606 rogid:853vdRxBjPdA2x4j4UKmZjBYhVY9606 rigid:SIawNke4YpTuE+IbfzOpmngcITI false - tandem tag:n-n - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R5 uniprotkb:Q8N0S6 intact:EBI-1003700|uniprotkb:A8K3Y1|ensembl:ENSP00000283006 intact:EBI-8467109|uniprotkb:Q5TEL5|uniprotkb:Q96ND4|intact:MINT-8417655|ensembl:ENSP00000323543|ensembl:ENSP00000356683|ensembl:ENSP00000507473 psi-mi:cenph_human(display_long)|uniprotkb:Interphase centromere complex protein 35(gene name synonym)|uniprotkb:ICEN35(gene name synonym)|uniprotkb:CENPH(gene name)|psi-mi:CENPH(display_short) psi-mi:cenpl_human(display_long)|uniprotkb:CENPL(gene name)|psi-mi:CENPL(display_short)|uniprotkb:C1orf155(gene name synonym)|uniprotkb:ICEN33(gene name synonym)|uniprotkb:Interphase centromere complex protein 33(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477520|imex:IM-26985-389 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_075060.1|ensembl:ENSG00000153044(gene)|ensembl:ENST00000283006(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0043515"(kinetochore binding)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051383"(kinetochore organization)|interpro:IPR040034|mint:Q9H3R5|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|interpro:IPR008426(Centromere H) refseq:NP_001164653.1|refseq:NP_001120653.1|refseq:NP_201576.1|ensembl:ENSG00000120334(gene)|ensembl:ENST00000345664(transcript)|ensembl:ENST00000367710(transcript)|ensembl:ENST00000682279(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR025204|mint:Q8N0S6|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025 - - comment:mint|comment:homomint|comment:"author score: 67" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:NcnQtHH8NhQ2AUePTPR3TRrpqaI9606 rogid:wzpFb9Z60Lx5LLjYbY3oU7OL0OI9606 rigid:jpKtxSTAL9aQH4buDxBNOTXEqPM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R5 uniprotkb:Q13352 intact:EBI-1003700|uniprotkb:A8K3Y1|ensembl:ENSP00000283006 intact:EBI-712105|ensembl:ENSP00000271002|uniprotkb:Q13353|uniprotkb:Q5RJ42|uniprotkb:Q5RJ44|uniprotkb:Q5RJ45|uniprotkb:Q7KYX2|uniprotkb:Q96CD5|uniprotkb:Q9UKB6|uniprotkb:B2R7D8 psi-mi:cenph_human(display_long)|uniprotkb:Interphase centromere complex protein 35(gene name synonym)|uniprotkb:ICEN35(gene name synonym)|uniprotkb:CENPH(gene name)|psi-mi:CENPH(display_short) psi-mi:cenpr_human(display_long)|uniprotkb:Nuclear receptor-interacting factor 3(gene name synonym)|uniprotkb:Integrin beta-3-binding protein(gene name synonym)|uniprotkb:Beta-3-endonexin(gene name synonym)|uniprotkb:ITGB3BP(gene name)|psi-mi:ITGB3BP(display_short)|uniprotkb:NRIF3(gene name synonym)|uniprotkb:CENPR(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477520|imex:IM-26985-389 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_075060.1|ensembl:ENSG00000153044(gene)|ensembl:ENST00000283006(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0043515"(kinetochore binding)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051383"(kinetochore organization)|interpro:IPR040034|mint:Q9H3R5|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|interpro:IPR008426(Centromere H) ensembl:ENSG00000142856(gene)|ensembl:ENST00000271002(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0034080"(CENP-A containing chromatin assembly)|go:"GO:0051301"(cell division)|interpro:IPR009601(Nuclear receptor co-activator NRIF3)|mint:Q13352|reactome:R-HSA-141444|reactome:R-HSA-205043|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-5663220|refseq:NP_001334077.1|refseq:NP_001193668.1|refseq:NP_055103.3 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:NcnQtHH8NhQ2AUePTPR3TRrpqaI9606 rogid:7GYfMmMv0+wKjQkvxDDcTn8Qx2Y9606 rigid:jpKtxSTAL9aQH4buDxBNOTXEqPM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R5 uniprotkb:Q6IPU0 intact:EBI-1003700|uniprotkb:A8K3Y1|ensembl:ENSP00000283006 intact:EBI-10250303|uniprotkb:B3KS17|uniprotkb:Q5T9F9|uniprotkb:Q5T9F8|uniprotkb:B3KRA5|ensembl:ENSP00000364737 psi-mi:cenph_human(display_long)|uniprotkb:Interphase centromere complex protein 35(gene name synonym)|uniprotkb:ICEN35(gene name synonym)|uniprotkb:CENPH(gene name)|psi-mi:CENPH(display_short) psi-mi:cenpp_human(display_long)|uniprotkb:CENPP(gene name)|psi-mi:CENPP(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477520|imex:IM-26985-389 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_075060.1|ensembl:ENSG00000153044(gene)|ensembl:ENST00000283006(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0043515"(kinetochore binding)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051383"(kinetochore organization)|interpro:IPR040034|mint:Q9H3R5|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|interpro:IPR008426(Centromere H) refseq:NP_001012267.1|refseq:NP_001273900.1|ensembl:ENSG00000188312(gene)|ensembl:ENST00000375587(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0034080"(CENP-A containing chromatin assembly)|interpro:IPR027801|mint:Q6IPU0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:NcnQtHH8NhQ2AUePTPR3TRrpqaI9606 rogid:X3bwDGWImA8oSEMMqbvulp3SliA9606 rigid:jpKtxSTAL9aQH4buDxBNOTXEqPM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R5 uniprotkb:Q71F23 intact:EBI-1003700|uniprotkb:A8K3Y1|ensembl:ENSP00000283006 intact:EBI-2515234|uniprotkb:Q09GN2|ensembl:ENSP00000281453|uniprotkb:Q32Q71|uniprotkb:A2RRD9|uniprotkb:Q9H5G1 psi-mi:cenph_human(display_long)|uniprotkb:Interphase centromere complex protein 35(gene name synonym)|uniprotkb:ICEN35(gene name synonym)|uniprotkb:CENPH(gene name)|psi-mi:CENPH(display_short) psi-mi:cenpu_human(display_long)|uniprotkb:CENPU(gene name)|psi-mi:CENPU(display_short)|uniprotkb:Centromere protein of 50 kDa(gene name synonym)|uniprotkb:ICEN24(gene name synonym)|uniprotkb:Interphase centromere complex protein 24(gene name synonym)|uniprotkb:KLIP1(gene name synonym)|uniprotkb:KSHV latent nuclear antigen-interacting protein 1(gene name synonym)|uniprotkb:MLF1-interacting protein(gene name synonym)|uniprotkb:MLF1IP(gene name synonym)|uniprotkb:PBIP1(gene name synonym)|uniprotkb:Polo-box-interacting protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477520|imex:IM-26985-389 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_075060.1|ensembl:ENSG00000153044(gene)|ensembl:ENST00000283006(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0043515"(kinetochore binding)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051383"(kinetochore organization)|interpro:IPR040034|mint:Q9H3R5|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|interpro:IPR008426(Centromere H) ensembl:ENSG00000151725(gene)|ensembl:ENST00000281453(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0034451"(centriolar satellite)|go:"GO:0043009"(chordate embryonic development)|interpro:IPR025214|mint:Q71F23|reactome:R-HSA-141444|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-2467813|refseq:NP_078905.2|dip:DIP-48539N - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:NcnQtHH8NhQ2AUePTPR3TRrpqaI9606 rogid:9FtaN8LMgqRrTXtmbt5NDbKCyus9606 rigid:jpKtxSTAL9aQH4buDxBNOTXEqPM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R5 uniprotkb:Q7L2Z9 intact:EBI-1003700|uniprotkb:A8K3Y1|ensembl:ENSP00000283006 intact:EBI-2350265|uniprotkb:Q6IN61|uniprotkb:Q9NVS5|uniprotkb:A8KAF1|ensembl:ENSP00000337289 psi-mi:cenph_human(display_long)|uniprotkb:Interphase centromere complex protein 35(gene name synonym)|uniprotkb:ICEN35(gene name synonym)|uniprotkb:CENPH(gene name)|psi-mi:CENPH(display_short) psi-mi:cenpq_human(display_long)|uniprotkb:CENPQ(gene name)|psi-mi:CENPQ(display_short)|uniprotkb:C6orf139(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477520|imex:IM-26985-389 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_075060.1|ensembl:ENSG00000153044(gene)|ensembl:ENST00000283006(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0043515"(kinetochore binding)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051383"(kinetochore organization)|interpro:IPR040034|mint:Q9H3R5|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|interpro:IPR008426(Centromere H) refseq:NP_060602.2|refseq:XP_005249262.1|ensembl:ENSG00000031691(gene)|ensembl:ENST00000335783(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0051310"(metaphase plate congression)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR025212|mint:Q7L2Z9|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025 - - comment:"author score: 27" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:NcnQtHH8NhQ2AUePTPR3TRrpqaI9606 rogid:qSVZT9uWH/55f1YtdJrC7U90clk9606 rigid:jpKtxSTAL9aQH4buDxBNOTXEqPM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R5 uniprotkb:Q9NSP4 intact:EBI-1003700|uniprotkb:A8K3Y1|ensembl:ENSP00000283006 intact:EBI-11051095|uniprotkb:B1AHQ9|uniprotkb:Q6I9W3|uniprotkb:A7LM22|ensembl:ENSP00000215980 psi-mi:cenph_human(display_long)|uniprotkb:Interphase centromere complex protein 35(gene name synonym)|uniprotkb:ICEN35(gene name synonym)|uniprotkb:CENPH(gene name)|psi-mi:CENPH(display_short) psi-mi:cenpm_human(display_long)|uniprotkb:CENPM(gene name)|psi-mi:CENPM(display_short)|uniprotkb:C22orf18(gene name synonym)|uniprotkb:ICEN39(gene name synonym)|uniprotkb:Interphase centromere complex protein 39(gene name synonym)|uniprotkb:PANE1(gene name synonym)|uniprotkb:Proliferation-associated nuclear element protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477520|imex:IM-26985-389 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_075060.1|ensembl:ENSG00000153044(gene)|ensembl:ENST00000283006(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0043515"(kinetochore binding)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051383"(kinetochore organization)|interpro:IPR040034|mint:Q9H3R5|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|interpro:IPR008426(Centromere H) refseq:NP_001002876.1|refseq:NP_001103685.1|refseq:NP_001291299.1|refseq:NP_001291300.1|refseq:NP_001291301.1|refseq:NP_001291302.1|refseq:NP_076958.1|ensembl:ENSG00000100162(gene)|ensembl:ENST00000215980(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR020987|interpro:IPR027417|mint:Q9NSP4|rcsb pdb:4P0T|rcsb pdb:4WAU|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025 - - comment:"author score: 83" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:NcnQtHH8NhQ2AUePTPR3TRrpqaI9606 rogid:Ei3FrYFSQRwyweYc/yqcenf5aXg9606 rigid:jpKtxSTAL9aQH4buDxBNOTXEqPM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R5 uniprotkb:Q92674 intact:EBI-1003700|uniprotkb:A8K3Y1|ensembl:ENSP00000283006 intact:EBI-11085153|uniprotkb:Q96ED0|uniprotkb:Q5JWZ9|ensembl:ENSP00000362018|ensembl:ENSP00000507595|ensembl:ENSP00000507927 psi-mi:cenph_human(display_long)|uniprotkb:Interphase centromere complex protein 35(gene name synonym)|uniprotkb:ICEN35(gene name synonym)|uniprotkb:CENPH(gene name)|psi-mi:CENPH(display_short) psi-mi:cenpi_human(display_long)|uniprotkb:CENPI(gene name)|psi-mi:CENPI(display_short)|uniprotkb:FSH primary response protein 1(gene name synonym)|uniprotkb:FSHPRH1(gene name synonym)|uniprotkb:Follicle-stimulating hormone primary response protein(gene name synonym)|uniprotkb:ICEN19(gene name synonym)|uniprotkb:Interphase centromere complex protein 19(gene name synonym)|uniprotkb:LRPR1(gene name synonym)|uniprotkb:Leucine-rich primary response protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477520|imex:IM-26985-389 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_075060.1|ensembl:ENSG00000153044(gene)|ensembl:ENST00000283006(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0043515"(kinetochore binding)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051383"(kinetochore organization)|interpro:IPR040034|mint:Q9H3R5|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|interpro:IPR008426(Centromere H) refseq:NP_006724.2|refseq:XP_005262168.1|refseq:XP_011529196.1|refseq:XP_011529197.1|refseq:XP_011529199.1|refseq:XP_011529201.1|refseq:NP_001305452.1|ensembl:ENSG00000102384(gene)|ensembl:ENST00000372927(transcript)|ensembl:ENST00000682095(transcript)|ensembl:ENST00000684367(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007548"(sex differentiation)|go:"GO:0016604"(nuclear body)|go:"GO:0034508"(centromere complex assembly)|interpro:IPR012485(Mis6)|mint:Q92674|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-2500257 - - comment:"author score: 86" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:NcnQtHH8NhQ2AUePTPR3TRrpqaI9606 rogid:LQS7ERffOiJEX+FEMvhaHhak/qw9606 rigid:jpKtxSTAL9aQH4buDxBNOTXEqPM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R5 uniprotkb:Q96H22 intact:EBI-1003700|uniprotkb:A8K3Y1|ensembl:ENSP00000283006 intact:EBI-2340053|uniprotkb:Q9NZ83|uniprotkb:B3KN53|uniprotkb:C9JJM5|uniprotkb:D3DUK8|uniprotkb:A8MZE6|uniprotkb:B4DJD1|uniprotkb:B4DPY7|uniprotkb:E7ES30|uniprotkb:E7ETS3|ensembl:ENSP00000305608 psi-mi:cenph_human(display_long)|uniprotkb:Interphase centromere complex protein 35(gene name synonym)|uniprotkb:ICEN35(gene name synonym)|uniprotkb:CENPH(gene name)|psi-mi:CENPH(display_short) psi-mi:cenpn_human(display_long)|uniprotkb:CENPN(gene name)|psi-mi:CENPN(display_short)|uniprotkb:C16orf60(gene name synonym)|uniprotkb:ICEN32(gene name synonym)|uniprotkb:Interphase centromere complex protein 32(gene name synonym)|uniprotkb:BM-309(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477520|imex:IM-26985-389 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_075060.1|ensembl:ENSG00000153044(gene)|ensembl:ENST00000283006(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0043515"(kinetochore binding)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051383"(kinetochore organization)|interpro:IPR040034|mint:Q9H3R5|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|interpro:IPR008426(Centromere H) refseq:XP_006721299.1|refseq:NP_001094094.2|refseq:NP_060925.2|refseq:NP_001094095.2|refseq:NP_001257402.1|refseq:NP_001257403.1|refseq:XP_016878945.1|ensembl:ENSG00000166451(gene)|ensembl:ENST00000305850(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR007902(CHL4)|mint:Q96H22|rcsb pdb:6C0W|rcsb pdb:6EQT|rcsb pdb:6MUO|rcsb pdb:6MUP|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|rcsb pdb:6BUZ - - comment:"author score: 104" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:NcnQtHH8NhQ2AUePTPR3TRrpqaI9606 rogid:mZN9Zgmz2AYSbhAFGobCUH++bnY9606 rigid:jpKtxSTAL9aQH4buDxBNOTXEqPM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R5 uniprotkb:Q9BS16 intact:EBI-1003700|uniprotkb:A8K3Y1|ensembl:ENSP00000283006 intact:EBI-6871750|ensembl:ENSP00000242872|ensembl:ENSP00000379911|ensembl:ENSP00000422421|uniprotkb:Q9H4L0 psi-mi:cenph_human(display_long)|uniprotkb:Interphase centromere complex protein 35(gene name synonym)|uniprotkb:ICEN35(gene name synonym)|uniprotkb:CENPH(gene name)|psi-mi:CENPH(display_short) psi-mi:cenpk_human(display_long)|uniprotkb:Protein AF-5alpha(gene name synonym)|uniprotkb:p33(gene name synonym)|uniprotkb:FKSG14(orf name)|uniprotkb:ICEN37(gene name synonym)|uniprotkb:Interphase centromere complex protein 37(gene name synonym)|uniprotkb:CENPK(gene name)|psi-mi:CENPK(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477520|imex:IM-26985-389 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_075060.1|ensembl:ENSG00000153044(gene)|ensembl:ENST00000283006(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0043515"(kinetochore binding)|go:"GO:0051382"(kinetochore assembly)|go:"GO:0051383"(kinetochore organization)|interpro:IPR040034|mint:Q9H3R5|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|interpro:IPR008426(Centromere H) refseq:XP_011541838.1|refseq:XP_016865179.1|refseq:XP_016865180.1|refseq:XP_016865181.1|ensembl:ENSG00000123219(gene)|ensembl:ENST00000242872(transcript)|ensembl:ENST00000396679(transcript)|ensembl:ENST00000514814(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000939"(inner kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR020993|mint:Q9BS16|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001253967.1|refseq:NP_071428.2 - - comment:"author score: 184" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:NcnQtHH8NhQ2AUePTPR3TRrpqaI9606 rogid:853vdRxBjPdA2x4j4UKmZjBYhVY9606 rigid:jpKtxSTAL9aQH4buDxBNOTXEqPM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y6F7 uniprotkb:P04908 intact:EBI-25477462|ensembl:ENSP00000250838|ensembl:ENSP00000372319|uniprotkb:A8K868 intact:EBI-358971|uniprotkb:Q76P63|uniprotkb:P28001|ensembl:ENSP00000303373|ensembl:ENSP00000483842 psi-mi:cdy2_human(display_long)|uniprotkb:CDY2A(gene name)|psi-mi:CDY2A(display_short)|uniprotkb:CDY2(gene name synonym)|uniprotkb:CDY2B(gene name)|psi-mi:CDY2B(display_short) psi-mi:h2a1b_human(display_long)|uniprotkb:H2AC4(gene name)|psi-mi:H2AC4(display_short)|uniprotkb:H2AC8(gene name)|psi-mi:H2AC8(display_short)|uniprotkb:H2AFA(gene name synonym)|uniprotkb:H2AFM(gene name synonym)|uniprotkb:HIST1H2AB(gene name synonym)|uniprotkb:HIST1H2AE(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/a(gene name synonym)|uniprotkb:Histone H2A/m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477490|imex:IM-26985-235 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000250838(transcript)|ensembl:ENST00000382867(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0007283"(spermatogenesis)|interpro:IPR000953(Chromo domain)|interpro:IPR001753(Crotonase, core)|interpro:IPR014748(Crontonase, C-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR029045|mint:Q9Y6F7|rcsb pdb:2FW2|ensembl:ENSG00000129873(gene)|ensembl:ENSG00000182415(gene)|refseq:NP_001001722.1|refseq:NP_004816.1 refseq:NP_003504.2|refseq:NP_066390.1|ensembl:ENSG00000277075(gene)|ensembl:ENSG00000278463(gene)|ensembl:ENST00000303910(transcript)|ensembl:ENST00000615868(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P04908|rcsb pdb:2CV5|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1V|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACL|rcsb pdb:6AEE|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6KE9|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V92|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|rcsb pdb:6JXD|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|dip:DIP-44197N - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:NY9VG4UUTZM4/TmSJooOBun6yP89606 rogid:4Qno1mMYZB6FdNoojrzulWLVq849606 rigid:6T5WTYJIXvnzI5ein4ynumXvMqA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y6F7 uniprotkb:P62805 intact:EBI-25477462|ensembl:ENSP00000250838|ensembl:ENSP00000372319|uniprotkb:A8K868 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:cdy2_human(display_long)|uniprotkb:CDY2A(gene name)|psi-mi:CDY2A(display_short)|uniprotkb:CDY2(gene name synonym)|uniprotkb:CDY2B(gene name)|psi-mi:CDY2B(display_short) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477490|imex:IM-26985-235 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000250838(transcript)|ensembl:ENST00000382867(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0007283"(spermatogenesis)|interpro:IPR000953(Chromo domain)|interpro:IPR001753(Crotonase, core)|interpro:IPR014748(Crontonase, C-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR029045|mint:Q9Y6F7|rcsb pdb:2FW2|ensembl:ENSG00000129873(gene)|ensembl:ENSG00000182415(gene)|refseq:NP_001001722.1|refseq:NP_004816.1 ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:NY9VG4UUTZM4/TmSJooOBun6yP89606 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 rigid:6T5WTYJIXvnzI5ein4ynumXvMqA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y6F7 uniprotkb:Q9Y6H1 intact:EBI-25477462|ensembl:ENSP00000250838|ensembl:ENSP00000372319|uniprotkb:A8K868 intact:EBI-2321769|uniprotkb:Q498C3|uniprotkb:Q6NZ50|ensembl:ENSP00000378812 psi-mi:cdy2_human(display_long)|uniprotkb:CDY2A(gene name)|psi-mi:CDY2A(display_short)|uniprotkb:CDY2(gene name synonym)|uniprotkb:CDY2B(gene name)|psi-mi:CDY2B(display_short) psi-mi:chch2_human(display_long)|uniprotkb:CHCHD2(gene name)|psi-mi:CHCHD2(display_short)|uniprotkb:C7orf17(gene name synonym)|uniprotkb:HCV NS2 trans-regulated protein(gene name synonym)|uniprotkb:Aging-associated gene 10 protein(gene name synonym)|uniprotkb:AAG10(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477490|imex:IM-26985-235 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000250838(transcript)|ensembl:ENST00000382867(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0007283"(spermatogenesis)|interpro:IPR000953(Chromo domain)|interpro:IPR001753(Crotonase, core)|interpro:IPR014748(Crontonase, C-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR029045|mint:Q9Y6F7|rcsb pdb:2FW2|ensembl:ENSG00000129873(gene)|ensembl:ENSG00000182415(gene)|refseq:NP_001001722.1|refseq:NP_004816.1 refseq:NP_057223.1|ensembl:ENSG00000106153(gene)|ensembl:ENST00000395422(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900037"(regulation of cellular response to hypoxia)|go:"GO:1905448"(positive regulation of mitochondrial ATP synthesis coupled electron transport)|interpro:IPR010625(CHCH)|mint:Q9Y6H1|reactome:R-HSA-1268020 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:NY9VG4UUTZM4/TmSJooOBun6yP89606 rogid:fdx3lE51+yZ1k3uwh8/LDKJC+CQ9606 rigid:6T5WTYJIXvnzI5ein4ynumXvMqA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y6F7 uniprotkb:Q9Y657 intact:EBI-25477462|ensembl:ENSP00000250838|ensembl:ENSP00000372319|uniprotkb:A8K868 intact:EBI-727129|uniprotkb:Q7KZJ8|uniprotkb:Q9GZT2|uniprotkb:Q9H0N7|uniprotkb:A8K0X6|uniprotkb:B3KRQ4|ensembl:ENSP00000365019 psi-mi:cdy2_human(display_long)|uniprotkb:CDY2A(gene name)|psi-mi:CDY2A(display_short)|uniprotkb:CDY2(gene name synonym)|uniprotkb:CDY2B(gene name)|psi-mi:CDY2B(display_short) psi-mi:spin1_human(display_long)|uniprotkb:Ovarian cancer-related protein(gene name synonym)|uniprotkb:SPIN1(gene name)|psi-mi:SPIN1(display_short)|uniprotkb:OCR(gene name synonym)|uniprotkb:SPIN(gene name synonym)|uniprotkb:Spindlin1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477490|imex:IM-26985-235 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000250838(transcript)|ensembl:ENST00000382867(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0007283"(spermatogenesis)|interpro:IPR000953(Chromo domain)|interpro:IPR001753(Crotonase, core)|interpro:IPR014748(Crontonase, C-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR029045|mint:Q9Y6F7|rcsb pdb:2FW2|ensembl:ENSG00000129873(gene)|ensembl:ENSG00000182415(gene)|refseq:NP_001001722.1|refseq:NP_004816.1 refseq:NP_006708.2|ensembl:ENSG00000106723(gene)|ensembl:ENST00000375859(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007276"(gamete generation)|go:"GO:0009303"(rRNA transcription)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR003671(Spindlin/spermiogenesis-specific protein)|interpro:IPR029565|interpro:IPR042567|mint:Q9Y657|rcsb pdb:2NS2|rcsb pdb:4H75|rcsb pdb:4MZF|rcsb pdb:4MZG|rcsb pdb:4MZH|rcsb pdb:5JSG|rcsb pdb:5JSJ|rcsb pdb:5Y5W|rcsb pdb:6I8B|rcsb pdb:6I8L|rcsb pdb:6I8Y|rcsb pdb:6QPL|rcsb pdb:7BQZ|rcsb pdb:7BU9|rcsb pdb:7CNA|dip:DIP-40062N - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:NY9VG4UUTZM4/TmSJooOBun6yP89606 rogid:OY/wCdms/yjDXj5aY2QffHXXXUY9606 rigid:6T5WTYJIXvnzI5ein4ynumXvMqA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y6F7 uniprotkb:Q13015 intact:EBI-25477462|ensembl:ENSP00000250838|ensembl:ENSP00000372319|uniprotkb:A8K868 intact:EBI-6269719|ensembl:ENSP00000357917 psi-mi:cdy2_human(display_long)|uniprotkb:CDY2A(gene name)|psi-mi:CDY2A(display_short)|uniprotkb:CDY2(gene name synonym)|uniprotkb:CDY2B(gene name)|psi-mi:CDY2B(display_short) psi-mi:af1q_human(display_long)|uniprotkb:MLLT11(gene name)|psi-mi:MLLT11(display_short)|uniprotkb:AF1Q(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477490|imex:IM-26985-235 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000250838(transcript)|ensembl:ENST00000382867(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0007283"(spermatogenesis)|interpro:IPR000953(Chromo domain)|interpro:IPR001753(Crotonase, core)|interpro:IPR014748(Crontonase, C-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR029045|mint:Q9Y6F7|rcsb pdb:2FW2|ensembl:ENSG00000129873(gene)|ensembl:ENSG00000182415(gene)|refseq:NP_001001722.1|refseq:NP_004816.1 ensembl:ENSG00000213190(gene)|ensembl:ENST00000368921(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR026778|interpro:IPR033461|mint:Q13015|refseq:NP_006809.1 - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:NY9VG4UUTZM4/TmSJooOBun6yP89606 rogid:23mnJAG1OcDgM7eT2rTi1Gv0ZgA9606 rigid:6T5WTYJIXvnzI5ein4ynumXvMqA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y6F7 uniprotkb:P07477 intact:EBI-25477462|ensembl:ENSP00000250838|ensembl:ENSP00000372319|uniprotkb:A8K868 intact:EBI-1222902|uniprotkb:A6NJ71|uniprotkb:Q92955|uniprotkb:Q9HAN4|uniprotkb:Q9HAN5|uniprotkb:Q9HAN6|uniprotkb:Q9HAN7|intact:EBI-1760472|intact:EBI-1965533|uniprotkb:A1A509|uniprotkb:Q5NV57|uniprotkb:Q7M4N3|uniprotkb:Q7M4N4|uniprotkb:B2R5I5|ensembl:ENSP00000308720|ensembl:ENSP00000479217 psi-mi:cdy2_human(display_long)|uniprotkb:CDY2A(gene name)|psi-mi:CDY2A(display_short)|uniprotkb:CDY2(gene name synonym)|uniprotkb:CDY2B(gene name)|psi-mi:CDY2B(display_short) psi-mi:try1_human(display_long)|uniprotkb:PRSS1(gene name)|psi-mi:PRSS1(display_short)|uniprotkb:TRP1(gene name synonym)|uniprotkb:TRY1(gene name synonym)|uniprotkb:TRYP1(gene name synonym)|uniprotkb:Trypsin I(gene name synonym)|uniprotkb:Cationic trypsinogen(gene name synonym)|uniprotkb:Serine protease 1(gene name synonym)|uniprotkb:Beta-trypsin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477490|imex:IM-26985-235 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000250838(transcript)|ensembl:ENST00000382867(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0007283"(spermatogenesis)|interpro:IPR000953(Chromo domain)|interpro:IPR001753(Crotonase, core)|interpro:IPR014748(Crontonase, C-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR029045|mint:Q9Y6F7|rcsb pdb:2FW2|ensembl:ENSG00000129873(gene)|ensembl:ENSG00000182415(gene)|refseq:NP_001001722.1|refseq:NP_004816.1 refseq:NP_002760.1|ensembl:ENSG00000204983(gene)|ensembl:ENSG00000274247(gene)|ensembl:ENST00000311737(transcript)|ensembl:ENST00000616256(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0007586"(digestion)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0072562"(blood microparticle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|mint:P07477|rcsb pdb:1FXY|rcsb pdb:1TRN|rcsb pdb:2RA3|rcsb pdb:4WWY|rcsb pdb:4WXV|reactome:R-HSA-1592389|reactome:R-HSA-196741 - - comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:NY9VG4UUTZM4/TmSJooOBun6yP89606 rogid:2elS/qMYj0sflxilyWfk3KPtGmo9606 rigid:6T5WTYJIXvnzI5ein4ynumXvMqA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y6F7 uniprotkb:O60906 intact:EBI-25477462|ensembl:ENSP00000250838|ensembl:ENSP00000372319|uniprotkb:A8K868 intact:EBI-12828299|ensembl:ENSP00000258052|uniprotkb:Q5TED1|uniprotkb:Q9BWR3 psi-mi:cdy2_human(display_long)|uniprotkb:CDY2A(gene name)|psi-mi:CDY2A(display_short)|uniprotkb:CDY2(gene name synonym)|uniprotkb:CDY2B(gene name)|psi-mi:CDY2B(display_short) psi-mi:nsma_human(display_long)|uniprotkb:SMPD2(gene name)|psi-mi:SMPD2(display_short)|uniprotkb:Lyso-platelet-activating factor-phospholipase C(gene name synonym)|uniprotkb:Neutral sphingomyelinase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477490|imex:IM-26985-235 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000250838(transcript)|ensembl:ENST00000382867(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0007283"(spermatogenesis)|interpro:IPR000953(Chromo domain)|interpro:IPR001753(Crotonase, core)|interpro:IPR014748(Crontonase, C-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR029045|mint:Q9Y6F7|rcsb pdb:2FW2|ensembl:ENSG00000129873(gene)|ensembl:ENSG00000182415(gene)|refseq:NP_001001722.1|refseq:NP_004816.1 ensembl:ENSG00000135587(gene)|ensembl:ENST00000258052(transcript)|go:"GO:0004620"(phospholipase activity)|go:"GO:0004767"(sphingomyelin phosphodiesterase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006684"(sphingomyelin metabolic process)|go:"GO:0006685"(sphingomyelin catabolic process)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0016020"(membrane)|go:"GO:0030149"(sphingolipid catabolic process)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0071944"(cell periphery)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR036691|interpro:IPR038772|mint:O60906|reactome:R-HSA-1660662|reactome:R-HSA-193681|reactome:R-HSA-5626978|refseq:NP_003071.2 - - comment:"author score: 32" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:NY9VG4UUTZM4/TmSJooOBun6yP89606 rogid:nEPi6zl3CV6lfUGjVvJHeECbllY9606 rigid:6T5WTYJIXvnzI5ein4ynumXvMqA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y6F7 uniprotkb:Q99417 intact:EBI-25477462|ensembl:ENSP00000250838|ensembl:ENSP00000372319|uniprotkb:A8K868 intact:EBI-716185|intact:EBI-2559925|uniprotkb:Q5TA64|uniprotkb:Q96HE2|uniprotkb:B2R4N0|ensembl:ENSP00000380702 psi-mi:cdy2_human(display_long)|uniprotkb:CDY2A(gene name)|psi-mi:CDY2A(display_short)|uniprotkb:CDY2(gene name synonym)|uniprotkb:CDY2B(gene name)|psi-mi:CDY2B(display_short) psi-mi:mycbp_human(display_long)|uniprotkb:Associate of Myc 1(gene name synonym)|uniprotkb:MYCBP(gene name)|psi-mi:MYCBP(display_short)|uniprotkb:AMY1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477490|imex:IM-26985-235 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENST00000250838(transcript)|ensembl:ENST00000382867(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0007283"(spermatogenesis)|interpro:IPR000953(Chromo domain)|interpro:IPR001753(Crotonase, core)|interpro:IPR014748(Crontonase, C-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR029045|mint:Q9Y6F7|rcsb pdb:2FW2|ensembl:ENSG00000129873(gene)|ensembl:ENSG00000182415(gene)|refseq:NP_001001722.1|refseq:NP_004816.1 refseq:NP_036465.2|ensembl:ENSG00000214114(gene)|ensembl:ENST00000397572(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007283"(spermatogenesis)|interpro:IPR026060|mint:Q99417|rcsb pdb:2YY0 - - comment:"author score: 41" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:NY9VG4UUTZM4/TmSJooOBun6yP89606 rogid:jIStn1A10DDkgTuwVeKpDPJ6tIs9606 rigid:6T5WTYJIXvnzI5ein4ynumXvMqA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JM3 uniprotkb:Q7Z3K3 intact:EBI-2560420|uniprotkb:Q8NC88|uniprotkb:B3KU06|uniprotkb:Q6P181|uniprotkb:Q9BST0|ensembl:ENSP00000354730|ensembl:ENSP00000496699 intact:EBI-1389308|uniprotkb:O75049|uniprotkb:Q5SZS2|uniprotkb:Q5SZS3|uniprotkb:Q5SZS4|uniprotkb:Q8TDZ7|uniprotkb:Q9Y4X7|uniprotkb:Q3LIC4|uniprotkb:Q5SZS1|intact:EBI-2560449|intact:EBI-11742841|uniprotkb:B4DTP8|uniprotkb:B4DYL9|uniprotkb:B7ZBY5|uniprotkb:E9PM80|intact:EBI-14072025|intact:EBI-17205119|intact:EBI-22321456|intact:EBI-12748249|intact:EBI-16429759|ensembl:ENSP00000271715 psi-mi:chap1_human(display_long)|uniprotkb:CHAMP(gene name synonym)|uniprotkb:CHAMP1(gene name)|psi-mi:CHAMP1(display_short)|uniprotkb:C13orf8(gene name synonym)|uniprotkb:CAMP(gene name synonym)|uniprotkb:KIAA1802(gene name synonym)|uniprotkb:ZNF828(gene name synonym)|uniprotkb:Zinc finger protein 828(gene name synonym) psi-mi:pogz_human(display_long)|uniprotkb:POGZ(gene name)|psi-mi:POGZ(display_short)|uniprotkb:KIAA0461(gene name synonym)|uniprotkb:Nbla00003(orf name)|uniprotkb:SUHW5(gene name synonym)|uniprotkb:ZNF280E(gene name synonym)|uniprotkb:ZNF635(gene name synonym)|uniprotkb:Suppressor of hairy wing homolog 5(gene name synonym)|uniprotkb:Zinc finger protein 280E(gene name synonym)|uniprotkb:Zinc finger protein 635(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477631|imex:IM-26985-537 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001157616.1|refseq:NP_001157617.1|refseq:NP_115812.1|ensembl:ENSG00000198824(gene)|ensembl:ENST00000361283(transcript)|ensembl:ENST00000643483(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0016604"(nuclear body)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0046872"(metal ion binding)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0090543"(Flemming body)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR039330|mint:Q96JM3|rcsb pdb:6EKJ|rcsb pdb:6EKL|rcsb pdb:5XPT|rcsb pdb:5XPU refseq:NP_001181866.1|refseq:NP_001181867.1|refseq:NP_055915.2|refseq:NP_665739.3|refseq:NP_997054.1|refseq:XP_016856234.1|refseq:XP_016856235.1|refseq:XP_016856237.1|refseq:XP_016856238.1|refseq:XP_005245056.1|refseq:XP_005245057.1|refseq:XP_005245058.1|refseq:XP_005245062.1|refseq:XP_005245063.1|dip:DIP-38044N|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSG00000143442(gene)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|ensembl:ENST00000271715(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR004875(CENP-B protein)|interpro:IPR006600(Centromere protein B, helix-turn-helix)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q7Z3K3|rcsb pdb:2E72|rcsb pdb:2N3A|rcsb pdb:6EMP - - comment:"author score: 80" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Di1yMiufHKsy384vPjOgdncmQXw9606 rogid:sCOIY8KsHRQtfcoSA9Tixl9yIsc9606 rigid:g9KCi7X1BZXvWv9Ma/6KabXrqU0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JM3 uniprotkb:P62805 intact:EBI-2560420|uniprotkb:Q8NC88|uniprotkb:B3KU06|uniprotkb:Q6P181|uniprotkb:Q9BST0|ensembl:ENSP00000354730|ensembl:ENSP00000496699 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:chap1_human(display_long)|uniprotkb:CHAMP(gene name synonym)|uniprotkb:CHAMP1(gene name)|psi-mi:CHAMP1(display_short)|uniprotkb:C13orf8(gene name synonym)|uniprotkb:CAMP(gene name synonym)|uniprotkb:KIAA1802(gene name synonym)|uniprotkb:ZNF828(gene name synonym)|uniprotkb:Zinc finger protein 828(gene name synonym) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477631|imex:IM-26985-537 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001157616.1|refseq:NP_001157617.1|refseq:NP_115812.1|ensembl:ENSG00000198824(gene)|ensembl:ENST00000361283(transcript)|ensembl:ENST00000643483(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0016604"(nuclear body)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0046872"(metal ion binding)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0090543"(Flemming body)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR039330|mint:Q96JM3|rcsb pdb:6EKJ|rcsb pdb:6EKL|rcsb pdb:5XPT|rcsb pdb:5XPU ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Di1yMiufHKsy384vPjOgdncmQXw9606 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 rigid:g9KCi7X1BZXvWv9Ma/6KabXrqU0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JM3 uniprotkb:P00734 intact:EBI-2560420|uniprotkb:Q8NC88|uniprotkb:B3KU06|uniprotkb:Q6P181|uniprotkb:Q9BST0|ensembl:ENSP00000354730|ensembl:ENSP00000496699 intact:EBI-297094|ensembl:ENSP00000308541|uniprotkb:B2R7F7|uniprotkb:B4E1A7|uniprotkb:Q4QZ40|uniprotkb:Q53H04|uniprotkb:Q53H06|uniprotkb:Q7Z7P3|uniprotkb:Q9UCA1|uniprotkb:Q69EZ7 psi-mi:chap1_human(display_long)|uniprotkb:CHAMP(gene name synonym)|uniprotkb:CHAMP1(gene name)|psi-mi:CHAMP1(display_short)|uniprotkb:C13orf8(gene name synonym)|uniprotkb:CAMP(gene name synonym)|uniprotkb:KIAA1802(gene name synonym)|uniprotkb:ZNF828(gene name synonym)|uniprotkb:Zinc finger protein 828(gene name synonym) psi-mi:thrb_human(display_long)|uniprotkb:F2(gene name)|psi-mi:F2(display_short)|uniprotkb:Coagulation factor II(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477631|imex:IM-26985-537 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001157616.1|refseq:NP_001157617.1|refseq:NP_115812.1|ensembl:ENSG00000198824(gene)|ensembl:ENST00000361283(transcript)|ensembl:ENST00000643483(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0016604"(nuclear body)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0046872"(metal ion binding)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0090543"(Flemming body)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR039330|mint:Q96JM3|rcsb pdb:6EKJ|rcsb pdb:6EKL|rcsb pdb:5XPT|rcsb pdb:5XPU rcsb pdb:1BTH|rcsb pdb:1C1U|rcsb pdb:1C1V|rcsb pdb:1C1W|rcsb pdb:1C4U|rcsb pdb:1C4V|rcsb pdb:1C4Y|rcsb pdb:1C5L|rcsb pdb:1C5N|rcsb pdb:1C5O|rcsb pdb:1CA8|rcsb pdb:1D3D|rcsb pdb:1D3P|rcsb pdb:1D3Q|rcsb pdb:1D3T|rcsb pdb:1D4P|rcsb pdb:1D6W|rcsb pdb:1BMN|rcsb pdb:1D9I|rcsb pdb:1DE7|rcsb pdb:1DIT|rcsb pdb:1DM4|rcsb pdb:1DOJ|rcsb pdb:1DWB|rcsb pdb:1DWC|rcsb pdb:1DWD|rcsb pdb:1LHF|rcsb pdb:1LHG|rcsb pdb:1MH0|rcsb pdb:1MU6|rcsb pdb:1MU8|rcsb pdb:1MUE|rcsb pdb:1NM6|rcsb pdb:1NO9|rcsb pdb:1NRN|rcsb pdb:1NRO|rcsb pdb:1NRP|rcsb pdb:1NRQ|rcsb pdb:1NRR|rcsb pdb:1NRS|rcsb pdb:1DWE|rcsb pdb:1NT1|rcsb pdb:1NU7|rcsb pdb:1NU9|rcsb pdb:1KTT|rcsb pdb:1LHC|rcsb pdb:1NY2|rcsb pdb:1NZQ|rcsb pdb:1LHD|rcsb pdb:1O0D|rcsb pdb:1O2G|rcsb pdb:1LHE|rcsb pdb:1O5G|rcsb pdb:1OOK|rcsb pdb:1OYT|rcsb pdb:1P8V|rcsb pdb:1PPB|rcsb pdb:1HAG|rcsb pdb:1HAH|rcsb pdb:1DX5|rcsb pdb:1E0F|rcsb pdb:1EB1|rcsb pdb:1HAI|rcsb pdb:1HAO|rcsb pdb:1EOJ|rcsb pdb:1EOL|rcsb pdb:1FPC|rcsb pdb:1FPH|rcsb pdb:1HAP|rcsb pdb:1HBT|rcsb pdb:1G30|rcsb pdb:1G32|rcsb pdb:1G37|rcsb pdb:1GHV|rcsb pdb:1HDT|rcsb pdb:1HGT|rcsb pdb:1GHW|rcsb pdb:1GHX|rcsb pdb:1GHY|rcsb pdb:1GJ4|rcsb pdb:1GJ5|rcsb pdb:1HLT|rcsb pdb:1HUT|rcsb pdb:1HXE|rcsb pdb:1HXF|rcsb pdb:1IHS|rcsb pdb:1IHT|rcsb pdb:1H8D|rcsb pdb:1H8I|rcsb pdb:1JMO|rcsb pdb:1JOU|rcsb pdb:1JWT|rcsb pdb:1K21|rcsb pdb:1K22|rcsb pdb:1KTS|ensembl:ENST00000311907(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006953"(acute-phase response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007596"(blood coagulation)|go:"GO:0008083"(growth factor activity)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010544"(negative regulation of platelet activation)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030168"(platelet activation)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|ensembl:ENSG00000180210(gene)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0051281"(positive regulation of release of sequestered calcium ion into cytosol)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051838"(cytolysis by host of symbiont cells)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070053"(thrombospondin receptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070945"(neutrophil-mediated killing of gram-negative bacterium)|go:"GO:0072562"(blood microparticle)|go:"GO:0042730"(fibrinolysis)|go:"GO:0090218"(positive regulation of lipid kinase activity)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1900738"(positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|interpro:IPR000001(Kringle)|rcsb pdb:1A3B|rcsb pdb:1A3E|interpro:IPR000294(Vitamin K-dependent carboxylation/gamma-carboxyglutamic region)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR003966(Peptidase S1A, prothrombin/thrombin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR013806(Kringle-like fold)|rcsb pdb:1A46|rcsb pdb:1A4W|interpro:IPR018056|rcsb pdb:1A5G|rcsb pdb:1A61|rcsb pdb:1ABI|interpro:IPR018114|interpro:IPR018992|interpro:IPR033116|rcsb pdb:1ABJ|rcsb pdb:1AD8|interpro:IPR035972|rcsb pdb:1AE8|rcsb pdb:1AFE|rcsb pdb:1AHT|rcsb pdb:1AI8|rcsb pdb:1AIX|rcsb pdb:1AWF|rcsb pdb:1AWH|rcsb pdb:1AY6|interpro:IPR037111|rcsb pdb:1B5G|rcsb pdb:1B7X|rcsb pdb:1BA8|rcsb pdb:1BB0|rcsb pdb:1BCU|interpro:IPR038178|rcsb pdb:1BHX|interpro:IPR043504|mint:P00734|rcsb pdb:1BMM|rcsb pdb:1A2C|rcsb pdb:2ZI2|rcsb pdb:2ZIQ|rcsb pdb:2ZNK|rcsb pdb:2ZO3|rcsb pdb:3B23|rcsb pdb:2ZHW|rcsb pdb:3B9F|rcsb pdb:3BEF|rcsb pdb:3BEI|rcsb pdb:3BF6|rcsb pdb:3BIU|rcsb pdb:3BIV|rcsb pdb:3BV9|rcsb pdb:3C1K|rcsb pdb:3C27|rcsb pdb:3D49|rcsb pdb:3DA9|rcsb pdb:3DD2|rcsb pdb:3DHK|rcsb pdb:3DT0|rcsb pdb:3DUX|rcsb pdb:3E6P|rcsb pdb:3EE0|rcsb pdb:3EGK|rcsb pdb:3EQ0|rcsb pdb:3F68|rcsb pdb:3GIC|rcsb pdb:3GIS|rcsb pdb:3HAT|rcsb pdb:3HKJ|rcsb pdb:3HTC|rcsb pdb:3JZ1|rcsb pdb:3JZ2|rcsb pdb:3K65|rcsb pdb:3LDX|rcsb pdb:3LU9|rcsb pdb:3NXP|rcsb pdb:3P17|rcsb pdb:3P6Z|rcsb pdb:3P70|rcsb pdb:3PMH|rcsb pdb:3PO1|rcsb pdb:3QDZ|rcsb pdb:3QGN|rcsb pdb:3QLP|rcsb pdb:3QTO|rcsb pdb:3QTV|rcsb pdb:3QWC|rcsb pdb:3QX5|rcsb pdb:1QBV|rcsb pdb:1QHR|rcsb pdb:1QJ1|rcsb pdb:1QJ6|rcsb pdb:1TB6|rcsb pdb:1QJ7|rcsb pdb:1QUR|rcsb pdb:1RD3|rcsb pdb:1TBZ|rcsb pdb:1RIW|rcsb pdb:1THP|rcsb pdb:1THR|rcsb pdb:1THS|rcsb pdb:1SB1|rcsb pdb:1SFQ|rcsb pdb:1SG8|rcsb pdb:1SGI|rcsb pdb:1SHH|rcsb pdb:1TMB|rcsb pdb:1SL3|rcsb pdb:1SR5|rcsb pdb:1T4U|rcsb pdb:1T4V|rcsb pdb:1TA2|rcsb pdb:1TMT|rcsb pdb:1TMU|rcsb pdb:1TOM|rcsb pdb:1TQ0|rcsb pdb:1TQ7|rcsb pdb:1TWX|rcsb pdb:1UMA|rcsb pdb:1UVS|rcsb pdb:1VR1|rcsb pdb:1VZQ|rcsb pdb:1W7G|rcsb pdb:1WAY|rcsb pdb:1WBG|rcsb pdb:1XM1|rcsb pdb:1XMN|rcsb pdb:1YPE|rcsb pdb:1YPG|rcsb pdb:1YPJ|rcsb pdb:1YPK|rcsb pdb:1YPL|rcsb pdb:1TA6|rcsb pdb:1YPM|rcsb pdb:1Z71|rcsb pdb:2AFQ|rcsb pdb:2ANK|rcsb pdb:2ANM|rcsb pdb:2B5T|rcsb pdb:2BDY|rcsb pdb:2BVR|rcsb pdb:2BVS|rcsb pdb:2BVX|rcsb pdb:2BXT|rcsb pdb:2BXU|rcsb pdb:2C8W|rcsb pdb:2C8X|rcsb pdb:2C8Y|rcsb pdb:2C8Z|rcsb pdb:2C90|rcsb pdb:2C93|rcsb pdb:2CF8|rcsb pdb:2CF9|rcsb pdb:1Z8I|rcsb pdb:2CN0|rcsb pdb:2FEQ|rcsb pdb:1Z8J|rcsb pdb:1ZGI|rcsb pdb:1ZGV|rcsb pdb:1ZRB|rcsb pdb:2A0Q|rcsb pdb:2A2X|rcsb pdb:2FES|rcsb pdb:2GDE|rcsb pdb:2GP9|rcsb pdb:2A45|rcsb pdb:2H9T|rcsb pdb:2HGT|rcsb pdb:2HNT|rcsb pdb:2HPP|rcsb pdb:2HPQ|rcsb pdb:2HWL|rcsb pdb:3RLW|rcsb pdb:3RLY|rcsb pdb:3RM0|rcsb pdb:3R3G|rcsb pdb:3RM2|rcsb pdb:3RML|rcsb pdb:3RMM|rcsb pdb:3RMN|rcsb pdb:3RMO|rcsb pdb:3S7H|rcsb pdb:3S7K|rcsb pdb:3SHA|rcsb pdb:3SHC|rcsb pdb:3SI3|rcsb pdb:3SI4|rcsb pdb:3SQE|rcsb pdb:3SQH|rcsb pdb:3SV2|rcsb pdb:3T5F|rcsb pdb:3TU7|rcsb pdb:3U69|rcsb pdb:3U8O|rcsb pdb:3U8R|rcsb pdb:3U8T|rcsb pdb:3U98|rcsb pdb:3U9A|rcsb pdb:3UTU|rcsb pdb:3UWJ|rcsb pdb:3VXE|rcsb pdb:3VXF|rcsb pdb:4AX9|rcsb pdb:4AYV|rcsb pdb:4AYY|rcsb pdb:4AZ2|rcsb pdb:4BAH|rcsb pdb:4BAK|rcsb pdb:4BAM|rcsb pdb:4BAN|rcsb pdb:4BAO|rcsb pdb:4BAQ|rcsb pdb:4BOH|rcsb pdb:4CH2|rcsb pdb:4CH8|rcsb pdb:4DIH|rcsb pdb:4DII|rcsb pdb:4DT7|rcsb pdb:4DY7|rcsb pdb:4E05|rcsb pdb:4E7R|rcsb pdb:4H6S|rcsb pdb:4H6T|rcsb pdb:4HFP|rcsb pdb:4HTC|rcsb pdb:4HZH|rcsb pdb:4I7Y|rcsb pdb:4LOY|rcsb pdb:4LXB|rcsb pdb:4LZ1|rcsb pdb:4LZ4|rcsb pdb:4MLF|rcsb pdb:4NZQ|rcsb pdb:4O03|rcsb pdb:4RKJ|rcsb pdb:4RKO|rcsb pdb:4RN6|rcsb pdb:4THN|rcsb pdb:4UD9|rcsb pdb:4UDW|rcsb pdb:4UE7|rcsb pdb:4UEH|rcsb pdb:4UFD|rcsb pdb:4UFE|rcsb pdb:4UFF|rcsb pdb:4UFG|rcsb pdb:4YES|rcsb pdb:5A2M|rcsb pdb:5AF9|rcsb pdb:4E06|rcsb pdb:5AFY|rcsb pdb:5AHG|rcsb pdb:5CMX|rcsb pdb:5DO4|rcsb pdb:5E8E|rcsb pdb:5EDK|rcsb pdb:5EDM|rcsb pdb:5EW1|rcsb pdb:5EW2|rcsb pdb:5GDS|rcsb pdb:5GIM|rcsb pdb:5JDU|rcsb pdb:5JFD|rcsb pdb:5JZY|rcsb pdb:5L6N|rcsb pdb:5MJT|rcsb pdb:5MLS|rcsb pdb:5MM6|rcsb pdb:5NHU|rcsb pdb:5TO3|rcsb pdb:5Z5W|rcsb pdb:5Z5X|rcsb pdb:6BJR|rcsb pdb:6C2W|rcsb pdb:6EO6|rcsb pdb:6EO7|rcsb pdb:6EO8|rcsb pdb:6EO9|rcsb pdb:6V5T|rcsb pdb:7KME|rcsb pdb:8KME|reactome:R-HSA-140837|reactome:R-HSA-140875|reactome:R-HSA-159740|reactome:R-HSA-159763|reactome:R-HSA-159782|reactome:R-HSA-202733|reactome:R-HSA-375276|reactome:R-HSA-381426|reactome:R-HSA-416476|rcsb pdb:5AFZ|rcsb pdb:2JH5|rcsb pdb:2JH6|rcsb pdb:2OD3|rcsb pdb:2PGB|rcsb pdb:2PGQ|rcsb pdb:2PKS|rcsb pdb:2PW8|rcsb pdb:2R2M|rcsb pdb:2THF|rcsb pdb:2UUF|rcsb pdb:2UUJ|rcsb pdb:2UUK|rcsb pdb:2V3H|rcsb pdb:2V3O|rcsb pdb:2ZC9|rcsb pdb:2ZDA|rcsb pdb:2ZDV|rcsb pdb:2ZF0|rcsb pdb:2ZFF|rcsb pdb:2ZFP|rcsb pdb:2ZFQ|rcsb pdb:2ZFR|rcsb pdb:2ZG0|rcsb pdb:2JH0|rcsb pdb:2ZGB|rcsb pdb:2ZGX|rcsb pdb:2ZHE|rcsb pdb:2ZHF|rcsb pdb:2ZHQ|reactome:R-HSA-76009|reactome:R-HSA-9657688|reactome:R-HSA-9672391|reactome:R-HSA-977606|reactome:R-HSA-456926|refseq:NP_000497.1|refseq:NP_001298186.1|dip:DIP-6115N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Di1yMiufHKsy384vPjOgdncmQXw9606 rogid:f6OQ6v3WbFpxr7N6GhfZOHjSsTQ9606 rigid:g9KCi7X1BZXvWv9Ma/6KabXrqU0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JM3 uniprotkb:P00742 intact:EBI-2560420|uniprotkb:Q8NC88|uniprotkb:B3KU06|uniprotkb:Q6P181|uniprotkb:Q9BST0|ensembl:ENSP00000354730|ensembl:ENSP00000496699 intact:EBI-719750|uniprotkb:Q14340|ensembl:ENSP00000364709 psi-mi:chap1_human(display_long)|uniprotkb:CHAMP(gene name synonym)|uniprotkb:CHAMP1(gene name)|psi-mi:CHAMP1(display_short)|uniprotkb:C13orf8(gene name synonym)|uniprotkb:CAMP(gene name synonym)|uniprotkb:KIAA1802(gene name synonym)|uniprotkb:ZNF828(gene name synonym)|uniprotkb:Zinc finger protein 828(gene name synonym) psi-mi:fa10_human(display_long)|uniprotkb:Stuart factor(gene name synonym)|uniprotkb:Stuart-Prower factor(gene name synonym)|uniprotkb:F10(gene name)|psi-mi:F10(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477631|imex:IM-26985-537 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001157616.1|refseq:NP_001157617.1|refseq:NP_115812.1|ensembl:ENSG00000198824(gene)|ensembl:ENST00000361283(transcript)|ensembl:ENST00000643483(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0016604"(nuclear body)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0046872"(metal ion binding)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0090543"(Flemming body)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR039330|mint:Q96JM3|rcsb pdb:6EKJ|rcsb pdb:6EKL|rcsb pdb:5XPT|rcsb pdb:5XPU refseq:NP_000495.1|ensembl:ENSG00000126218(gene)|ensembl:ENST00000375559(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0007596"(blood coagulation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031233"(intrinsic component of external side of plasma membrane)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000294(Vitamin K-dependent carboxylation/gamma-carboxyglutamic region)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR012224(Peptidase S1A, coagulation factor VII/IX/X/C/Z)|interpro:IPR017857(Coagulation factor, subset, Gla region)|interpro:IPR018097|interpro:IPR018114|interpro:IPR033116|interpro:IPR035972|interpro:IPR043504|mint:P00742|rcsb pdb:1C5M|rcsb pdb:1EZQ|rcsb pdb:1F0R|rcsb pdb:1F0S|rcsb pdb:1FAX|rcsb pdb:1FJS|rcsb pdb:1FXY|rcsb pdb:1G2L|rcsb pdb:1G2M|rcsb pdb:1HCG|rcsb pdb:1IOE|rcsb pdb:1IQE|rcsb pdb:1IQF|rcsb pdb:1IQG|rcsb pdb:1IQH|rcsb pdb:1IQI|rcsb pdb:1IQJ|rcsb pdb:1IQK|rcsb pdb:1IQL|rcsb pdb:1IQM|rcsb pdb:1IQN|rcsb pdb:1KSN|rcsb pdb:1LPG|rcsb pdb:1LPK|rcsb pdb:1LPZ|rcsb pdb:1LQD|rcsb pdb:1MQ5|rcsb pdb:1MQ6|rcsb pdb:1MSX|rcsb pdb:1NFU|rcsb pdb:1NFW|rcsb pdb:1NFX|rcsb pdb:1NFY|rcsb pdb:1NL8|rcsb pdb:1P0S|rcsb pdb:1V3X|rcsb pdb:1WU1|rcsb pdb:1XKA|rcsb pdb:1XKB|rcsb pdb:1Z6E|rcsb pdb:2BMG|rcsb pdb:2BOH|rcsb pdb:2BOK|rcsb pdb:2BQ6|rcsb pdb:2BQ7|rcsb pdb:2BQW|rcsb pdb:2CJI|rcsb pdb:2D1J|rcsb pdb:2EI6|rcsb pdb:2EI7|rcsb pdb:2EI8|rcsb pdb:2FZZ|rcsb pdb:2G00|rcsb pdb:2GD4|rcsb pdb:2H9E|rcsb pdb:2J2U|rcsb pdb:2J34|rcsb pdb:2J38|rcsb pdb:2J4I|rcsb pdb:2J94|rcsb pdb:2J95|rcsb pdb:2P16|rcsb pdb:2P3F|rcsb pdb:2P3T|rcsb pdb:2P3U|rcsb pdb:2P93|rcsb pdb:2P94|rcsb pdb:2P95|rcsb pdb:2PHB|rcsb pdb:2PR3|rcsb pdb:2Q1J|rcsb pdb:2RA0|rcsb pdb:2UWL|rcsb pdb:2UWO|rcsb pdb:2UWP|rcsb pdb:2VH0|rcsb pdb:2VH6|rcsb pdb:2VVC|rcsb pdb:2VVU|rcsb pdb:2VVV|rcsb pdb:2VWL|rcsb pdb:2VWM|rcsb pdb:2VWN|rcsb pdb:2VWO|rcsb pdb:2W26|rcsb pdb:2W3I|rcsb pdb:2W3K|rcsb pdb:2WYG|rcsb pdb:2WYJ|rcsb pdb:2XBV|rcsb pdb:2XBW|rcsb pdb:2XBX|rcsb pdb:2XBY|rcsb pdb:2XC0|rcsb pdb:2JKH|rcsb pdb:2XC4|rcsb pdb:2XC5|rcsb pdb:2Y5F|rcsb pdb:2Y5G|rcsb pdb:2Y5H|rcsb pdb:2Y7X|rcsb pdb:2Y7Z|rcsb pdb:2Y80|rcsb pdb:2Y81|rcsb pdb:2Y82|rcsb pdb:3CEN|rcsb pdb:3CS7|rcsb pdb:3ENS|rcsb pdb:3FFG|rcsb pdb:3HPT|rcsb pdb:3IIT|rcsb pdb:3K9X|rcsb pdb:3KL6|rcsb pdb:3KQB|rcsb pdb:3KQC|rcsb pdb:3KQD|rcsb pdb:3KQE|rcsb pdb:3LIW|rcsb pdb:3M36|rcsb pdb:3M37|rcsb pdb:3Q3K|rcsb pdb:3SW2|rcsb pdb:3TK6|rcsb pdb:4A7I|rcsb pdb:4BTI|rcsb pdb:4BTT|rcsb pdb:4BTU|rcsb pdb:4Y6D|rcsb pdb:4Y71|rcsb pdb:4Y76|rcsb pdb:4Y79|rcsb pdb:4Y7A|rcsb pdb:4Y7B|rcsb pdb:4ZH8|rcsb pdb:4ZHA|rcsb pdb:5JQY|rcsb pdb:5JTC|rcsb pdb:5JZ8|rcsb pdb:5JZU|rcsb pdb:5K0H|rcsb pdb:5VOE|rcsb pdb:5VOF|rcsb pdb:6Q9F|rcsb pdb:6Q9I|rcsb pdb:6RK9|rcsb pdb:6YYW|rcsb pdb:6YYX|rcsb pdb:6YYY|rcsb pdb:6Z6Q|rcsb pdb:6Z6R|rcsb pdb:7BMI|rcsb pdb:7BMJ|rcsb pdb:7E6J|rcsb pdb:3TK5|reactome:R-HSA-140834|reactome:R-HSA-140837|reactome:R-HSA-140875|reactome:R-HSA-159740|reactome:R-HSA-159763|reactome:R-HSA-159782|reactome:R-HSA-9672383|reactome:R-HSA-9672396|reactome:R-HSA-9673202|refseq:NP_001299603.1|refseq:NP_001299604.1|dip:DIP-29896N - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Di1yMiufHKsy384vPjOgdncmQXw9606 rogid:EiG38fLKwrbGJftF5k4xjLvlYhA9606 rigid:g9KCi7X1BZXvWv9Ma/6KabXrqU0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JM3 uniprotkb:Q969R5 intact:EBI-2560420|uniprotkb:Q8NC88|uniprotkb:B3KU06|uniprotkb:Q6P181|uniprotkb:Q9BST0|ensembl:ENSP00000354730|ensembl:ENSP00000496699 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 psi-mi:chap1_human(display_long)|uniprotkb:CHAMP(gene name synonym)|uniprotkb:CHAMP1(gene name)|psi-mi:CHAMP1(display_short)|uniprotkb:C13orf8(gene name synonym)|uniprotkb:CAMP(gene name synonym)|uniprotkb:KIAA1802(gene name synonym)|uniprotkb:ZNF828(gene name synonym)|uniprotkb:Zinc finger protein 828(gene name synonym) psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477631|imex:IM-26985-537 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001157616.1|refseq:NP_001157617.1|refseq:NP_115812.1|ensembl:ENSG00000198824(gene)|ensembl:ENST00000361283(transcript)|ensembl:ENST00000643483(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0016604"(nuclear body)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0046872"(metal ion binding)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0090543"(Flemming body)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR039330|mint:Q96JM3|rcsb pdb:6EKJ|rcsb pdb:6EKL|rcsb pdb:5XPT|rcsb pdb:5XPU refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750 - - comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Di1yMiufHKsy384vPjOgdncmQXw9606 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rigid:g9KCi7X1BZXvWv9Ma/6KabXrqU0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JM3 uniprotkb:P02656 intact:EBI-2560420|uniprotkb:Q8NC88|uniprotkb:B3KU06|uniprotkb:Q6P181|uniprotkb:Q9BST0|ensembl:ENSP00000354730|ensembl:ENSP00000496699 intact:EBI-1220113|uniprotkb:Q08E83|uniprotkb:Q6Q786|ensembl:ENSP00000227667 psi-mi:chap1_human(display_long)|uniprotkb:CHAMP(gene name synonym)|uniprotkb:CHAMP1(gene name)|psi-mi:CHAMP1(display_short)|uniprotkb:C13orf8(gene name synonym)|uniprotkb:CAMP(gene name synonym)|uniprotkb:KIAA1802(gene name synonym)|uniprotkb:ZNF828(gene name synonym)|uniprotkb:Zinc finger protein 828(gene name synonym) psi-mi:apoc3_human(display_long)|uniprotkb:APOC3(gene name)|psi-mi:APOC3(display_short)|uniprotkb:Apolipoprotein C3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477631|imex:IM-26985-537 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001157616.1|refseq:NP_001157617.1|refseq:NP_115812.1|ensembl:ENSG00000198824(gene)|ensembl:ENST00000361283(transcript)|ensembl:ENST00000643483(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0016604"(nuclear body)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0046872"(metal ion binding)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0090543"(Flemming body)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR039330|mint:Q96JM3|rcsb pdb:6EKJ|rcsb pdb:6EKL|rcsb pdb:5XPT|rcsb pdb:5XPU refseq:NP_000031.1|ensembl:ENSG00000110245(gene)|ensembl:ENST00000227667(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005769"(early endosome)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010897"(negative regulation of triglyceride catabolic process)|go:"GO:0010903"(negative regulation of very-low-density lipoprotein particle remodeling)|go:"GO:0010916"(negative regulation of very-low-density lipoprotein particle clearance)|go:"GO:0010987"(negative regulation of high-density lipoprotein particle clearance)|go:"GO:0010989"(negative regulation of low-density lipoprotein particle clearance)|go:"GO:0015485"(cholesterol binding)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034363"(intermediate-density lipoprotein particle)|go:"GO:0034366"(spherical high-density lipoprotein particle)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:0034382"(chylomicron remnant clearance)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0045833"(negative regulation of lipid metabolic process)|go:"GO:0048261"(negative regulation of receptor-mediated endocytosis)|go:"GO:0050995"(negative regulation of lipid catabolic process)|go:"GO:0051005"(negative regulation of lipoprotein lipase activity)|go:"GO:0055102"(lipase inhibitor activity)|go:"GO:0060621"(negative regulation of cholesterol import)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070653"(high-density lipoprotein particle receptor binding)|interpro:IPR008403(Apolipoprotein CIII)|interpro:IPR038195|mint:P02656|rcsb pdb:2JQ3|reactome:R-HSA-8963888|reactome:R-HSA-8963901|reactome:R-HSA-8964058|reactome:R-HSA-975634 - - comment:"author score: 28" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Di1yMiufHKsy384vPjOgdncmQXw9606 rogid:DDj33pQWDh0i5+mwMy16Dmg6JPg9606 rigid:g9KCi7X1BZXvWv9Ma/6KabXrqU0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JM3 uniprotkb:Q13185 intact:EBI-2560420|uniprotkb:Q8NC88|uniprotkb:B3KU06|uniprotkb:Q6P181|uniprotkb:Q9BST0|ensembl:ENSP00000354730|ensembl:ENSP00000496699 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 psi-mi:chap1_human(display_long)|uniprotkb:CHAMP(gene name synonym)|uniprotkb:CHAMP1(gene name)|psi-mi:CHAMP1(display_short)|uniprotkb:C13orf8(gene name synonym)|uniprotkb:CAMP(gene name synonym)|uniprotkb:KIAA1802(gene name synonym)|uniprotkb:ZNF828(gene name synonym)|uniprotkb:Zinc finger protein 828(gene name synonym) psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477631|imex:IM-26985-537 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001157616.1|refseq:NP_001157617.1|refseq:NP_115812.1|ensembl:ENSG00000198824(gene)|ensembl:ENST00000361283(transcript)|ensembl:ENST00000643483(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0016604"(nuclear body)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0046872"(metal ion binding)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0090543"(Flemming body)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR039330|mint:Q96JM3|rcsb pdb:6EKJ|rcsb pdb:6EKL|rcsb pdb:5XPT|rcsb pdb:5XPU go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N - - comment:"author score: 75" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Di1yMiufHKsy384vPjOgdncmQXw9606 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rigid:g9KCi7X1BZXvWv9Ma/6KabXrqU0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UKF6 uniprotkb:O95816 intact:EBI-1044699|uniprotkb:O14769|uniprotkb:Q96F36|uniprotkb:Q53RS2|ensembl:ENSP00000238112 intact:EBI-355275|uniprotkb:Q08AS9|uniprotkb:Q6FID0|uniprotkb:B4DXE2|ensembl:ENSP00000359727|intact:EBI-11068407 psi-mi:cpsf3_human(display_long)|uniprotkb:Cleavage and polyadenylation specificity factor 73 kDa subunit(gene name synonym)|uniprotkb:mRNA 3'-end-processing endonuclease CPSF-73(gene name synonym)|uniprotkb:CPSF3(gene name)|psi-mi:CPSF3(display_short)|uniprotkb:CPSF73(gene name synonym) psi-mi:bag2_human(display_long)|uniprotkb:BAG2(gene name)|psi-mi:BAG2(display_short)|uniprotkb:Bcl-2-associated athanogene 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477793|imex:IM-26985-161 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057291.1|ensembl:ENSG00000119203(gene)|ensembl:ENST00000238112(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|interpro:IPR021718|interpro:IPR022712|interpro:IPR036866|mint:Q9UKF6|rcsb pdb:2I7T|rcsb pdb:2I7V|rcsb pdb:6M8Q|rcsb pdb:6V4X|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|dip:DIP-42501N refseq:NP_004273.1|refseq:XP_011513301.1|refseq:XP_005249547.1|ensembl:ENSG00000112208(gene)|ensembl:ENST00000370693(transcript)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0019538"(protein metabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1901588"(dendritic microtubule)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|mint:O95816|reactome:R-HSA-3371453|refseq:XP_011513300.1 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lpTAUhlcFjFt2tHErN9igCjWTzs9606 rogid:nBGGBIQc/3P0mwp7N/XuTGLOrg89606 rigid:VZPU70LsUhjBhoWkTaNOHQ6VHYs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UKF6 uniprotkb:Q9UNE7 intact:EBI-1044699|uniprotkb:O14769|uniprotkb:Q96F36|uniprotkb:Q53RS2|ensembl:ENSP00000238112 intact:EBI-357085|uniprotkb:O60526|uniprotkb:Q969U2|uniprotkb:Q9HBT1|uniprotkb:A2IDB9|ensembl:ENSP00000219548 psi-mi:cpsf3_human(display_long)|uniprotkb:Cleavage and polyadenylation specificity factor 73 kDa subunit(gene name synonym)|uniprotkb:mRNA 3'-end-processing endonuclease CPSF-73(gene name synonym)|uniprotkb:CPSF3(gene name)|psi-mi:CPSF3(display_short)|uniprotkb:CPSF73(gene name synonym) psi-mi:chip_human(display_long)|uniprotkb:CHIP(gene name synonym)|uniprotkb:STUB1(gene name)|psi-mi:STUB1(display_short)|uniprotkb:PP1131(orf name)|uniprotkb:Carboxy terminus of Hsp70-interacting protein(gene name synonym)|uniprotkb:STIP1 homology and U box-containing protein 1(gene name synonym)|uniprotkb:CLL-associated antigen KW-8(gene name synonym)|uniprotkb:Antigen NY-CO-7(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CHIP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477793|imex:IM-26985-161 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057291.1|ensembl:ENSG00000119203(gene)|ensembl:ENST00000238112(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|interpro:IPR021718|interpro:IPR022712|interpro:IPR036866|mint:Q9UKF6|rcsb pdb:2I7T|rcsb pdb:2I7V|rcsb pdb:6M8Q|rcsb pdb:6V4X|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|dip:DIP-42501N dip:DIP-29752N|refseq:NP_005852.2|refseq:NP_001280126.1|ensembl:ENSG00000103266(gene)|ensembl:ENST00000219548(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031943"(regulation of glucocorticoid metabolic process)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046332"(SMAD binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0030579"(ubiquitin-dependent SMAD protein catabolic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090035"(positive regulation of chaperone-mediated protein complex assembly)|go:"GO:0101031"(chaperone complex)|interpro:IPR003613(U box)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019734|interpro:IPR041312|mint:Q9UNE7|rcsb pdb:4KBQ|rcsb pdb:6EFK|rcsb pdb:6NSV|reactome:R-HSA-2173788|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-8863795|reactome:R-HSA-8939902|reactome:R-HSA-8948751|reactome:R-HSA-983168 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lpTAUhlcFjFt2tHErN9igCjWTzs9606 rogid:h4QyIM0TptgkQppPUgiKn68XjP49606 rigid:VZPU70LsUhjBhoWkTaNOHQ6VHYs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UKF6 uniprotkb:Q9NVR5 intact:EBI-1044699|uniprotkb:O14769|uniprotkb:Q96F36|uniprotkb:Q53RS2|ensembl:ENSP00000238112 intact:EBI-9392930|uniprotkb:Q86TR1|uniprotkb:Q969Z5|uniprotkb:Q86TY8|uniprotkb:C0JAP7|uniprotkb:B9WS54|ensembl:ENSP00000298292 psi-mi:cpsf3_human(display_long)|uniprotkb:Cleavage and polyadenylation specificity factor 73 kDa subunit(gene name synonym)|uniprotkb:mRNA 3'-end-processing endonuclease CPSF-73(gene name synonym)|uniprotkb:CPSF3(gene name)|psi-mi:CPSF3(display_short)|uniprotkb:CPSF73(gene name synonym) psi-mi:ktu_human(display_long)|uniprotkb:DNAAF2(gene name)|psi-mi:DNAAF2(display_short)|uniprotkb:C14orf104(gene name synonym)|uniprotkb:Dynein assembly factor 2, axonemal(gene name synonym)|uniprotkb:KTU(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477793|imex:IM-26985-161 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057291.1|ensembl:ENSG00000119203(gene)|ensembl:ENST00000238112(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|interpro:IPR021718|interpro:IPR022712|interpro:IPR036866|mint:Q9UKF6|rcsb pdb:2I7T|rcsb pdb:2I7V|rcsb pdb:6M8Q|rcsb pdb:6V4X|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|dip:DIP-42501N refseq:NP_001077377.1|refseq:NP_060609.2|dip:DIP-59041N|ensembl:ENSG00000165506(gene)|ensembl:ENST00000298292(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003351"(epithelial cilium movement involved in extracellular fluid movement)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0036158"(outer dynein arm assembly)|go:"GO:0036159"(inner dynein arm assembly)|go:"GO:0060285"(cilium-dependent cell motility)|go:"GO:0061966"(establishment of left/right asymmetry)|go:"GO:0070286"(axonemal dynein complex assembly)|go:"GO:0120293"(dynein axonemal particle)|interpro:IPR012981(Nop17p)|interpro:IPR034727|interpro:IPR041442|mint:Q9NVR5 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lpTAUhlcFjFt2tHErN9igCjWTzs9606 rogid:0ILCb1hggxCP1t8PFo2dClvPsRM9606 rigid:VZPU70LsUhjBhoWkTaNOHQ6VHYs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UKF6 uniprotkb:Q7Z6J8 intact:EBI-1044699|uniprotkb:O14769|uniprotkb:Q96F36|uniprotkb:Q53RS2|ensembl:ENSP00000238112 intact:EBI-9379147|uniprotkb:B4DP63|uniprotkb:Q75UG0|uniprotkb:Q5T4W2|uniprotkb:Q9NT42|uniprotkb:Q6IPR4|ensembl:ENSP00000358762 psi-mi:cpsf3_human(display_long)|uniprotkb:Cleavage and polyadenylation specificity factor 73 kDa subunit(gene name synonym)|uniprotkb:mRNA 3'-end-processing endonuclease CPSF-73(gene name synonym)|uniprotkb:CPSF3(gene name)|psi-mi:CPSF3(display_short)|uniprotkb:CPSF73(gene name synonym) psi-mi:ube3d_human(display_long)|uniprotkb:UBE3D(gene name)|psi-mi:UBE3D(display_short)|uniprotkb:C6orf157(gene name synonym)|uniprotkb:H10BH(gene name synonym)|uniprotkb:UBE2CBP(gene name synonym)|uniprotkb:UbcH10-binding protein with a HECT-like domain(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2C-binding protein(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase E3D(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477793|imex:IM-26985-161 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057291.1|ensembl:ENSG00000119203(gene)|ensembl:ENST00000238112(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|interpro:IPR021718|interpro:IPR022712|interpro:IPR036866|mint:Q9UKF6|rcsb pdb:2I7T|rcsb pdb:2I7V|rcsb pdb:6M8Q|rcsb pdb:6V4X|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|dip:DIP-42501N refseq:NP_001291366.1|refseq:NP_944602.1|ensembl:ENSG00000118420(gene)|ensembl:ENST00000369747(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0030332"(cyclin binding)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019193|mint:Q7Z6J8|reactome:R-HSA-983168 - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lpTAUhlcFjFt2tHErN9igCjWTzs9606 rogid:F4Rnc9zJhfNndZpYOJ5e5wrqyNY9606 rigid:VZPU70LsUhjBhoWkTaNOHQ6VHYs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UKF6 uniprotkb:Q9NZM5 intact:EBI-1044699|uniprotkb:O14769|uniprotkb:Q96F36|uniprotkb:Q53RS2|ensembl:ENSP00000238112 intact:EBI-720156|uniprotkb:Q9BTC6|uniprotkb:Q9HAX6|uniprotkb:Q9NPP1|uniprotkb:Q9NPR4|uniprotkb:Q9UFI2|ensembl:ENSP00000246802 psi-mi:cpsf3_human(display_long)|uniprotkb:Cleavage and polyadenylation specificity factor 73 kDa subunit(gene name synonym)|uniprotkb:mRNA 3'-end-processing endonuclease CPSF-73(gene name synonym)|uniprotkb:CPSF3(gene name)|psi-mi:CPSF3(display_short)|uniprotkb:CPSF73(gene name synonym) psi-mi:nop53_human(display_long)|uniprotkb:NOP53(gene name)|psi-mi:NOP53(display_short)|uniprotkb:GLT(gene name synonym)|uniprotkb:GLTSCR2(gene name synonym)|uniprotkb:Glioma tumor suppressor candidate region gene 2 protein(gene name synonym)|uniprotkb:PICT1(gene name synonym)|uniprotkb:Protein interacting with carboxyl terminus 1(gene name synonym)|uniprotkb:p60(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477793|imex:IM-26985-161 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057291.1|ensembl:ENSG00000119203(gene)|ensembl:ENST00000238112(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|interpro:IPR021718|interpro:IPR022712|interpro:IPR036866|mint:Q9UKF6|rcsb pdb:2I7T|rcsb pdb:2I7V|rcsb pdb:6M8Q|rcsb pdb:6V4X|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|dip:DIP-42501N refseq:NP_056525.2|ensembl:ENSG00000105373(gene)|ensembl:ENST00000246802(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006364"(rRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0039535"(regulation of RIG-I signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0003723"(RNA binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1901797"(negative regulation of signal transduction by p53 class mediator)|go:"GO:1901837"(negative regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902570"(protein localization to nucleolus)|go:"GO:1903006"(positive regulation of protein K63-linked deubiquitination)|go:"GO:1903715"(regulation of aerobic respiration)|go:"GO:1990173"(protein localization to nucleoplasm)|interpro:IPR011687(P60-like)|mint:Q9NZM5|go:"GO:0050821"(protein stabilization) - - comment:"author score: 27" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lpTAUhlcFjFt2tHErN9igCjWTzs9606 rogid:64EYf68f9eP9SfPBJhjbxuJcn2g9606 rigid:VZPU70LsUhjBhoWkTaNOHQ6VHYs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UKF6 uniprotkb:P33240 intact:EBI-1044699|uniprotkb:O14769|uniprotkb:Q96F36|uniprotkb:Q53RS2|ensembl:ENSP00000238112 intact:EBI-711360|uniprotkb:Q5H951|uniprotkb:Q6LA74|uniprotkb:Q8N502|ensembl:ENSP00000362063 psi-mi:cpsf3_human(display_long)|uniprotkb:Cleavage and polyadenylation specificity factor 73 kDa subunit(gene name synonym)|uniprotkb:mRNA 3'-end-processing endonuclease CPSF-73(gene name synonym)|uniprotkb:CPSF3(gene name)|psi-mi:CPSF3(display_short)|uniprotkb:CPSF73(gene name synonym) psi-mi:cstf2_human(display_long)|uniprotkb:CSTF2(gene name)|psi-mi:CSTF2(display_short)|uniprotkb:CF-1 64 kDa subunit(gene name synonym)|uniprotkb:Cleavage stimulation factor 64 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477793|imex:IM-26985-161 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057291.1|ensembl:ENSG00000119203(gene)|ensembl:ENST00000238112(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|interpro:IPR021718|interpro:IPR022712|interpro:IPR036866|mint:Q9UKF6|rcsb pdb:2I7T|rcsb pdb:2I7V|rcsb pdb:6M8Q|rcsb pdb:6V4X|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|dip:DIP-42501N refseq:NP_001293138.1|ensembl:ENSG00000101811(gene)|ensembl:ENST00000372972(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0016604"(nuclear body)|go:"GO:0071920"(cleavage body)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR025742|interpro:IPR026896|interpro:IPR033105|interpro:IPR035979|interpro:IPR038192|mint:P33240|rcsb pdb:1P1T|rcsb pdb:2J8P|rcsb pdb:6Q2I|rcsb pdb:6TZE|reactome:R-HSA-6784531|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|refseq:NP_001316.1|dip:DIP-36129N - - comment:"author score: 27" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lpTAUhlcFjFt2tHErN9igCjWTzs9606 rogid:oZ/4DPJOEWflU05127TEp+ezQi89606 rigid:VZPU70LsUhjBhoWkTaNOHQ6VHYs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UKF6 uniprotkb:Q6UN15 intact:EBI-1044699|uniprotkb:O14769|uniprotkb:Q96F36|uniprotkb:Q53RS2|ensembl:ENSP00000238112 intact:EBI-1021914|uniprotkb:Q0VGE0|uniprotkb:Q499Y4|uniprotkb:Q49AU3|uniprotkb:Q7Z608|uniprotkb:Q8WVN3|uniprotkb:Q96F80|uniprotkb:Q9H077|intact:EBI-11535474|ensembl:ENSP00000336752|uniprotkb:B4DIR3|uniprotkb:G3XAD6 psi-mi:cpsf3_human(display_long)|uniprotkb:Cleavage and polyadenylation specificity factor 73 kDa subunit(gene name synonym)|uniprotkb:mRNA 3'-end-processing endonuclease CPSF-73(gene name synonym)|uniprotkb:CPSF3(gene name)|psi-mi:CPSF3(display_short)|uniprotkb:CPSF73(gene name synonym) psi-mi:fip1_human(display_long)|uniprotkb:Factor interacting with PAP(gene name synonym)|uniprotkb:FIP1-like 1 protein(gene name synonym)|uniprotkb:Rearranged in hypereosinophilia(gene name synonym)|uniprotkb:FIP1L1(gene name)|psi-mi:FIP1L1(display_short)|uniprotkb:FIP1(gene name synonym)|uniprotkb:RHE(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477793|imex:IM-26985-161 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057291.1|ensembl:ENSG00000119203(gene)|ensembl:ENST00000238112(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|interpro:IPR021718|interpro:IPR022712|interpro:IPR036866|mint:Q9UKF6|rcsb pdb:2I7T|rcsb pdb:2I7V|rcsb pdb:6M8Q|rcsb pdb:6V4X|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|dip:DIP-42501N ensembl:ENST00000306932|ensembl:ENSP00000302993|ensembl:ENSP00000336752|ensembl:ENST00000358575|ensembl:ENSP00000351383|ensembl:ENST00000507922|ensembl:ENSP00000425456|refseq:NP_001128409.1|refseq:NP_001128410.1|refseq:NP_112179.2|ensembl:ENSG00000145216(gene)|ensembl:ENST00000337488(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR007854(Fip1)|mint:Q6UN15|rcsb pdb:7K95|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|reactome:R-HSA-9673766|dip:DIP-42503N - - comment:"author score: 32" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lpTAUhlcFjFt2tHErN9igCjWTzs9606 rogid:41uK1l8RV99q4k4Z7K9zeG3TJHA9606 rigid:VZPU70LsUhjBhoWkTaNOHQ6VHYs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UKF6 uniprotkb:Q10570 intact:EBI-1044699|uniprotkb:O14769|uniprotkb:Q96F36|uniprotkb:Q53RS2|ensembl:ENSP00000238112 intact:EBI-347859|ensembl:ENSP00000478145|ensembl:ENSP00000484669|ensembl:ENSP00000495020|ensembl:ENSP00000495102|uniprotkb:Q96AF0 psi-mi:cpsf3_human(display_long)|uniprotkb:Cleavage and polyadenylation specificity factor 73 kDa subunit(gene name synonym)|uniprotkb:mRNA 3'-end-processing endonuclease CPSF-73(gene name synonym)|uniprotkb:CPSF3(gene name)|psi-mi:CPSF3(display_short)|uniprotkb:CPSF73(gene name synonym) psi-mi:cpsf1_human(display_long)|uniprotkb:CPSF1(gene name)|psi-mi:CPSF1(display_short)|uniprotkb:CPSF160(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 160 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477793|imex:IM-26985-161 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057291.1|ensembl:ENSG00000119203(gene)|ensembl:ENST00000238112(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|interpro:IPR021718|interpro:IPR022712|interpro:IPR036866|mint:Q9UKF6|rcsb pdb:2I7T|rcsb pdb:2I7V|rcsb pdb:6M8Q|rcsb pdb:6V4X|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|dip:DIP-42501N rcsb pdb:6F9N|rcsb pdb:6FBS|rcsb pdb:6FUW|rcsb pdb:6URG|rcsb pdb:6URO|reactome:R-HSA-159231|reactome:R-HSA-6784531|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:6DNH|reactome:R-HSA-77595|ensembl:ENSG00000071894(gene)|ensembl:ENSG00000285049(gene)|ensembl:ENST00000616140(transcript)|ensembl:ENST00000620219(transcript)|ensembl:ENST00000643746(transcript)|ensembl:ENST00000644539(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|mint:Q10570|rcsb pdb:6BLY|rcsb pdb:6BM0|refseq:NP_037423.2|dip:DIP-32694N - - comment:"author score: 41" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lpTAUhlcFjFt2tHErN9igCjWTzs9606 rogid:YZdY/qkUWUDbe+Dw3g9bY9DFbig9606 rigid:VZPU70LsUhjBhoWkTaNOHQ6VHYs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UKF6 uniprotkb:Q9C0J8 intact:EBI-1044699|uniprotkb:O14769|uniprotkb:Q96F36|uniprotkb:Q53RS2|ensembl:ENSP00000238112 intact:EBI-712637|uniprotkb:Q6NUQ0|uniprotkb:Q587J1|uniprotkb:Q05DP8|uniprotkb:Q53FG9|uniprotkb:Q9NUL1|uniprotkb:Q69YF7|ensembl:ENSP00000325377 psi-mi:cpsf3_human(display_long)|uniprotkb:Cleavage and polyadenylation specificity factor 73 kDa subunit(gene name synonym)|uniprotkb:mRNA 3'-end-processing endonuclease CPSF-73(gene name synonym)|uniprotkb:CPSF3(gene name)|psi-mi:CPSF3(display_short)|uniprotkb:CPSF73(gene name synonym) psi-mi:wdr33_human(display_long)|uniprotkb:WDR33(gene name)|psi-mi:WDR33(display_short)|uniprotkb:WDC146(gene name synonym)|uniprotkb:WD repeat-containing protein 33(gene name synonym)|uniprotkb:WD repeat-containing protein of 146 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477793|imex:IM-26985-161 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057291.1|ensembl:ENSG00000119203(gene)|ensembl:ENST00000238112(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|interpro:IPR021718|interpro:IPR022712|interpro:IPR036866|mint:Q9UKF6|rcsb pdb:2I7T|rcsb pdb:2I7V|rcsb pdb:6M8Q|rcsb pdb:6V4X|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|dip:DIP-42501N refseq:XP_011509738.1|refseq:NP_001006623.1|refseq:NP_060853.3|refseq:NP_001006624.1|ensembl:ENSG00000136709(gene)|ensembl:ENST00000322313(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005581"(collagen trimer)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006301"(postreplication repair)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0007283"(spermatogenesis)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q9C0J8|rcsb pdb:6BLY|rcsb pdb:6BM0|rcsb pdb:6DNH|rcsb pdb:6F9N|rcsb pdb:6FBS|rcsb pdb:6FUW|rcsb pdb:6URG|rcsb pdb:6URO|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595 - - comment:"author score: 47" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lpTAUhlcFjFt2tHErN9igCjWTzs9606 rogid:FzGeASJyKaYaqFQfFBYby692REg9606 rigid:VZPU70LsUhjBhoWkTaNOHQ6VHYs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UKF6 uniprotkb:Q92797 intact:EBI-1044699|uniprotkb:O14769|uniprotkb:Q96F36|uniprotkb:Q53RS2|ensembl:ENSP00000238112 intact:EBI-1051992|uniprotkb:O00521|uniprotkb:O00689|uniprotkb:O00733|uniprotkb:Q59GT5|uniprotkb:Q8N2U5|ensembl:ENSP00000245934 psi-mi:cpsf3_human(display_long)|uniprotkb:Cleavage and polyadenylation specificity factor 73 kDa subunit(gene name synonym)|uniprotkb:mRNA 3'-end-processing endonuclease CPSF-73(gene name synonym)|uniprotkb:CPSF3(gene name)|psi-mi:CPSF3(display_short)|uniprotkb:CPSF73(gene name synonym) psi-mi:sympk_human(display_long)|uniprotkb:SYMPK(gene name)|psi-mi:SYMPK(display_short)|uniprotkb:SPK(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477793|imex:IM-26985-161 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057291.1|ensembl:ENSG00000119203(gene)|ensembl:ENST00000238112(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|interpro:IPR021718|interpro:IPR022712|interpro:IPR036866|mint:Q9UKF6|rcsb pdb:2I7T|rcsb pdb:2I7V|rcsb pdb:6M8Q|rcsb pdb:6V4X|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|dip:DIP-42501N go:"GO:0016604"(nuclear body)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0097165"(nuclear stress granule)|ensembl:ENSG00000125755(gene)|ensembl:ENST00000245934(transcript)|interpro:IPR011989(Armadillo-like helical)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021850|interpro:IPR022075|interpro:IPR032460|mint:Q92797|rcsb pdb:3O2Q|rcsb pdb:3O2S|rcsb pdb:3O2T|rcsb pdb:3ODR|go:"GO:0005829"(cytosol)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0007155"(cell adhesion)|refseq:NP_004810.2|refseq:XP_011525656.1|refseq:XP_005259343.1|dip:DIP-42506N|rcsb pdb:3ODS|rcsb pdb:4H3H|rcsb pdb:4H3K|rcsb pdb:6V4X|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595 - - comment:"author score: 52" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lpTAUhlcFjFt2tHErN9igCjWTzs9606 rogid:+svYKfmD5gCiOxf9FxGUZKCNhtQ9606 rigid:VZPU70LsUhjBhoWkTaNOHQ6VHYs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UKF6 uniprotkb:Q9P2I0 intact:EBI-1044699|uniprotkb:O14769|uniprotkb:Q96F36|uniprotkb:Q53RS2|ensembl:ENSP00000238112 intact:EBI-1043224|uniprotkb:Q6NSJ1|uniprotkb:Q9H3W7|ensembl:ENSP00000298875|uniprotkb:B3KME1 psi-mi:cpsf3_human(display_long)|uniprotkb:Cleavage and polyadenylation specificity factor 73 kDa subunit(gene name synonym)|uniprotkb:mRNA 3'-end-processing endonuclease CPSF-73(gene name synonym)|uniprotkb:CPSF3(gene name)|psi-mi:CPSF3(display_short)|uniprotkb:CPSF73(gene name synonym) psi-mi:cpsf2_human(display_long)|uniprotkb:Cleavage and polyadenylation specificity factor 100 kDa subunit(gene name synonym)|uniprotkb:CPSF2(gene name)|psi-mi:CPSF2(display_short)|uniprotkb:CPSF100(gene name synonym)|uniprotkb:KIAA1367(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477793|imex:IM-26985-161 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057291.1|ensembl:ENSG00000119203(gene)|ensembl:ENST00000238112(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|interpro:IPR021718|interpro:IPR022712|interpro:IPR036866|mint:Q9UKF6|rcsb pdb:2I7T|rcsb pdb:2I7V|rcsb pdb:6M8Q|rcsb pdb:6V4X|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|dip:DIP-42501N interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|interpro:IPR022712|interpro:IPR025069|interpro:IPR027075|interpro:IPR035639|interpro:IPR036866|mint:Q9P2I0|rcsb pdb:6URG|rcsb pdb:6V4X|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|ensembl:ENSG00000165934(gene)|ensembl:ENST00000298875(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|go:"GO:0016020"(membrane)|refseq:NP_059133.1|refseq:NP_001309201.1|dip:DIP-42500N - - comment:"author score: 58" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lpTAUhlcFjFt2tHErN9igCjWTzs9606 rogid:RYiaQ8q9VM7htGre4S8PkSQaCz89606 rigid:VZPU70LsUhjBhoWkTaNOHQ6VHYs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UKF6 uniprotkb:O95639 intact:EBI-1044699|uniprotkb:O14769|uniprotkb:Q96F36|uniprotkb:Q53RS2|ensembl:ENSP00000238112 intact:EBI-725860|uniprotkb:Q86TF8|uniprotkb:Q9BTW6|uniprotkb:Q6FGE6|uniprotkb:D6W5S8|ensembl:ENSP00000292476 psi-mi:cpsf3_human(display_long)|uniprotkb:Cleavage and polyadenylation specificity factor 73 kDa subunit(gene name synonym)|uniprotkb:mRNA 3'-end-processing endonuclease CPSF-73(gene name synonym)|uniprotkb:CPSF3(gene name)|psi-mi:CPSF3(display_short)|uniprotkb:CPSF73(gene name synonym) psi-mi:cpsf4_human(display_long)|uniprotkb:Cleavage and polyadenylation specificity factor 30 kDa subunit(gene name synonym)|uniprotkb:NS1 effector domain-binding protein 1(gene name synonym)|uniprotkb:No arches homolog(gene name synonym)|uniprotkb:CPSF4(gene name)|psi-mi:CPSF4(display_short)|uniprotkb:CPSF30(gene name synonym)|uniprotkb:NAR(gene name synonym)|uniprotkb:NEB1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477793|imex:IM-26985-161 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057291.1|ensembl:ENSG00000119203(gene)|ensembl:ENST00000238112(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|interpro:IPR021718|interpro:IPR022712|interpro:IPR036866|mint:Q9UKF6|rcsb pdb:2I7T|rcsb pdb:2I7V|rcsb pdb:6M8Q|rcsb pdb:6V4X|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0046872"(metal ion binding)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|dip:DIP-42501N refseq:NP_001075028.1|refseq:NP_006684.1|refseq:NP_001305089.1|refseq:NP_001305090.1|refseq:NP_001305091.1|ensembl:ENSG00000160917(gene)|ensembl:ENST00000292476(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036855|interpro:IPR036875|interpro:IPR041686|mint:O95639|rcsb pdb:2D9N|rcsb pdb:2RHK|rcsb pdb:6DNH|rcsb pdb:6FBS|rcsb pdb:6FUW|rcsb pdb:6URG|rcsb pdb:6URO|rcsb pdb:7K95|reactome:R-HSA-159231|reactome:R-HSA-168315|reactome:R-HSA-6784531|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|dip:DIP-48675N - - comment:"author score: 60" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lpTAUhlcFjFt2tHErN9igCjWTzs9606 rogid:CTNuFmbdKiPNvBJPEHoLi7WvoYM9606 rigid:VZPU70LsUhjBhoWkTaNOHQ6VHYs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P49711 uniprotkb:Q9UPW6 intact:EBI-932887|uniprotkb:Q53XI7|uniprotkb:B5MC38|uniprotkb:Q59EL8|ensembl:ENSP00000264010|ensembl:ENSP00000493495|ensembl:ENSP00000494408|ensembl:ENSP00000494538|ensembl:ENSP00000495348 intact:EBI-8298169|ensembl:ENSP00000260926|ensembl:ENSP00000401112|ensembl:ENSP00000405420|uniprotkb:Q3ZB87|uniprotkb:Q4V763|intact:MINT-2822679|uniprotkb:A8K5Z8 psi-mi:ctcf_human(display_long)|uniprotkb:CCCTC-binding factor(gene name synonym)|uniprotkb:CTCFL paralog(gene name synonym)|uniprotkb:11-zinc finger protein(gene name synonym)|uniprotkb:CTCF(gene name)|psi-mi:CTCF(display_short) psi-mi:satb2_human(display_long)|uniprotkb:SATB2(gene name)|psi-mi:SATB2(display_short)|uniprotkb:KIAA1034(gene name synonym)|uniprotkb:Special AT-rich sequence-binding protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477859|imex:IM-26985-311 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006556.1|refseq:NP_001177951.1|refseq:XP_016878357.1|dip:DIP-35252N|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006306"(DNA methylation)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0040030"(obsolete regulation of molecular function, epigenetic)|go:"GO:0043035"(chromatin insulator sequence binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071514"(genomic imprinting)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P49711|rcsb pdb:1X6H|rcsb pdb:2CT1|rcsb pdb:5K5H|rcsb pdb:5K5I|rcsb pdb:5K5J|rcsb pdb:5K5L|rcsb pdb:5KKQ|rcsb pdb:5T00|rcsb pdb:5T0U|rcsb pdb:5UND|rcsb pdb:5YEF|rcsb pdb:5YEG|rcsb pdb:5YEH|rcsb pdb:5YEL|rcsb pdb:6QNX|reactome:R-HSA-5617472|ensembl:ENSG00000102974(gene)|ensembl:ENST00000264010(transcript)|ensembl:ENST00000642819(transcript)|ensembl:ENST00000644753(transcript)|ensembl:ENST00000645699(transcript)|ensembl:ENST00000646076(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding) ensembl:ENSG00000119042(gene)|ensembl:ENST00000260926(transcript)|ensembl:ENST00000417098(transcript)|ensembl:ENST00000457245(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002076"(osteoblast development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021902"(commitment of neuronal cell to specific neuron type in forebrain)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071310"(cellular response to organic substance)|interpro:IPR001356(Homeobox)|interpro:IPR003350(Homeodomain protein CUT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR032355|interpro:IPR032392|interpro:IPR038216|interpro:IPR038224|interpro:IPR039673|mint:Q9UPW6|rcsb pdb:1WI3|rcsb pdb:1WIZ|rcsb pdb:2CSF|reactome:R-HSA-4551638|reactome:R-HSA-8940973|refseq:XP_011509142.1|refseq:XP_006712435.1|refseq:NP_001165988.1|refseq:NP_001165980.1|refseq:NP_056080.1|dip:DIP-60551N - - comment:mint|function:May play an important role in palate formation|function:"Chromosomal aberrations involving SATB2 are found in isolated cleft palate. Translocation t(2;7); translocation t(2;11)"|function:"Defects in SATB2 are the cause of isolated cleft palate with mental retardation [MIM:119540]. Patients manifest cleft palate, craniofacial dysmorphism and profound mental retardation"|comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:hy9n/DVCzpfSi0EGigAjOZUvnIU9606 rogid:/dQFGKi08prg2Xjhsj4sqW77Cl09606 rigid:7P7Suf5ATQcl33HLwShLm7v71aU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P49711 uniprotkb:Q96DG6 intact:EBI-932887|uniprotkb:Q53XI7|uniprotkb:B5MC38|uniprotkb:Q59EL8|ensembl:ENSP00000264010|ensembl:ENSP00000493495|ensembl:ENSP00000494408|ensembl:ENSP00000494538|ensembl:ENSP00000495348 intact:EBI-1044268|uniprotkb:Q8TED6|uniprotkb:D3DTC7|ensembl:ENSP00000296658 psi-mi:ctcf_human(display_long)|uniprotkb:CCCTC-binding factor(gene name synonym)|uniprotkb:CTCFL paralog(gene name synonym)|uniprotkb:11-zinc finger protein(gene name synonym)|uniprotkb:CTCF(gene name)|psi-mi:CTCF(display_short) psi-mi:cmbl_human(display_long)|uniprotkb:CMBL(gene name)|psi-mi:CMBL(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477859|imex:IM-26985-311 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006556.1|refseq:NP_001177951.1|refseq:XP_016878357.1|dip:DIP-35252N|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006306"(DNA methylation)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0040030"(obsolete regulation of molecular function, epigenetic)|go:"GO:0043035"(chromatin insulator sequence binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071514"(genomic imprinting)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P49711|rcsb pdb:1X6H|rcsb pdb:2CT1|rcsb pdb:5K5H|rcsb pdb:5K5I|rcsb pdb:5K5J|rcsb pdb:5K5L|rcsb pdb:5KKQ|rcsb pdb:5T00|rcsb pdb:5T0U|rcsb pdb:5UND|rcsb pdb:5YEF|rcsb pdb:5YEG|rcsb pdb:5YEH|rcsb pdb:5YEL|rcsb pdb:6QNX|reactome:R-HSA-5617472|ensembl:ENSG00000102974(gene)|ensembl:ENST00000264010(transcript)|ensembl:ENST00000642819(transcript)|ensembl:ENST00000644753(transcript)|ensembl:ENST00000645699(transcript)|ensembl:ENST00000646076(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding) refseq:NP_620164.1|ensembl:ENSG00000164237(gene)|ensembl:ENST00000296658(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002925(Dienelactone hydrolase)|interpro:IPR029058|interpro:IPR042946|mint:Q96DG6|reactome:R-HSA-211945|refseq:XP_016864523.1|refseq:XP_016864524.1 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:hy9n/DVCzpfSi0EGigAjOZUvnIU9606 rogid:nIOgS/jTgYbRXndPjCCMtqb0cHU9606 rigid:7P7Suf5ATQcl33HLwShLm7v71aU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P49711 uniprotkb:P67870 intact:EBI-932887|uniprotkb:Q53XI7|uniprotkb:B5MC38|uniprotkb:Q59EL8|ensembl:ENSP00000264010|ensembl:ENSP00000493495|ensembl:ENSP00000494408|ensembl:ENSP00000494538|ensembl:ENSP00000495348 intact:EBI-348169|ensembl:ENSP00000365025|ensembl:ENSP00000365026|ensembl:ENSP00000365042|ensembl:ENSP00000372919|ensembl:ENSP00000372925|ensembl:ENSP00000382980|ensembl:ENSP00000390900|ensembl:ENSP00000391038|ensembl:ENSP00000393756|ensembl:ENSP00000394855|ensembl:ENSP00000395275|ensembl:ENSP00000400188|ensembl:ENSP00000407018|ensembl:ENSP00000407379|ensembl:ENSP00000409510|ensembl:ENSP00000410802|ensembl:ENSP00000411322|ensembl:ENSP00000412520|ensembl:ENSP00000413469|ensembl:ENSP00000415237|ensembl:ENSP00000415303|uniprotkb:P07312|uniprotkb:P13862|uniprotkb:Q4VX47|intact:EBI-3866975|uniprotkb:B0UXA9 psi-mi:ctcf_human(display_long)|uniprotkb:CCCTC-binding factor(gene name synonym)|uniprotkb:CTCFL paralog(gene name synonym)|uniprotkb:11-zinc finger protein(gene name synonym)|uniprotkb:CTCF(gene name)|psi-mi:CTCF(display_short) psi-mi:csk2b_human(display_long)|uniprotkb:Phosvitin(gene name synonym)|uniprotkb:Protein G5a(gene name synonym)|uniprotkb:CSNK2B(gene name)|psi-mi:CSNK2B(display_short)|uniprotkb:CK2N(gene name synonym)|uniprotkb:G5A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477859|imex:IM-26985-311 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006556.1|refseq:NP_001177951.1|refseq:XP_016878357.1|dip:DIP-35252N|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006306"(DNA methylation)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0040030"(obsolete regulation of molecular function, epigenetic)|go:"GO:0043035"(chromatin insulator sequence binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071514"(genomic imprinting)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P49711|rcsb pdb:1X6H|rcsb pdb:2CT1|rcsb pdb:5K5H|rcsb pdb:5K5I|rcsb pdb:5K5J|rcsb pdb:5K5L|rcsb pdb:5KKQ|rcsb pdb:5T00|rcsb pdb:5T0U|rcsb pdb:5UND|rcsb pdb:5YEF|rcsb pdb:5YEG|rcsb pdb:5YEH|rcsb pdb:5YEL|rcsb pdb:6QNX|reactome:R-HSA-5617472|ensembl:ENSG00000102974(gene)|ensembl:ENST00000264010(transcript)|ensembl:ENST00000642819(transcript)|ensembl:ENST00000644753(transcript)|ensembl:ENST00000645699(transcript)|ensembl:ENST00000646076(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding) ensembl:ENSG00000204435(gene)|ensembl:ENSG00000230700(gene)|ensembl:ENSG00000206406(gene)|ensembl:ENSG00000232960(gene)|ensembl:ENSG00000224398(gene)|ensembl:ENSG00000224774(gene)|ensembl:ENSG00000228875(gene)|ensembl:ENST00000375882(transcript)|ensembl:ENST00000383427(transcript)|ensembl:ENST00000383433(transcript)|ensembl:ENST00000400110(transcript)|ensembl:ENST00000412802(transcript)|ensembl:ENST00000418230(transcript)|ensembl:ENST00000422567(transcript)|ensembl:ENST00000429633(transcript)|ensembl:ENST00000431476(transcript)|ensembl:ENST00000436169(transcript)|ensembl:ENST00000443673(transcript)|ensembl:ENST00000448596(transcript)|ensembl:ENST00000451917(transcript)|ensembl:ENST00000452985(transcript)|ensembl:ENST00000453234(transcript)|ensembl:ENST00000454382(transcript)|ensembl:ENST00000454511(transcript)|ensembl:ENST00000455161(transcript)|ensembl:ENST00000458330(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0007165"(signal transduction)|ensembl:ENST00000375865(transcript)|ensembl:ENST00000375866(transcript)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016363"(nuclear matrix)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032927"(positive regulation of activin receptor signaling pathway)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0033574"(response to testosterone)|go:"GO:0034622"|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR035991|mint:P67870|rcsb pdb:1DS5|rcsb pdb:1JWH|go:"GO:0008134"(transcription factor binding)|rcsb pdb:1QF8|rcsb pdb:3EED|rcsb pdb:4DGL|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6798695|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:6Q38|refseq:NP_001311.3|refseq:NP_001269314.1|dip:DIP-131N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:hy9n/DVCzpfSi0EGigAjOZUvnIU9606 rogid:ZTHJjCqHg2dE7B+WoSU28VSMuPg9606 rigid:7P7Suf5ATQcl33HLwShLm7v71aU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P49711 uniprotkb:P35030 intact:EBI-932887|uniprotkb:Q53XI7|uniprotkb:B5MC38|uniprotkb:Q59EL8|ensembl:ENSP00000264010|ensembl:ENSP00000493495|ensembl:ENSP00000494408|ensembl:ENSP00000494538|ensembl:ENSP00000495348 intact:EBI-1221209|uniprotkb:Q5VXV0|intact:EBI-2825937|uniprotkb:A8CED3|uniprotkb:F8W7P3|uniprotkb:Q6ISJ4|uniprotkb:P15951|uniprotkb:Q15665|uniprotkb:Q9UQV3|uniprotkb:A9Z1Y4|uniprotkb:E7ES07|uniprotkb:A8CED1 psi-mi:ctcf_human(display_long)|uniprotkb:CCCTC-binding factor(gene name synonym)|uniprotkb:CTCFL paralog(gene name synonym)|uniprotkb:11-zinc finger protein(gene name synonym)|uniprotkb:CTCF(gene name)|psi-mi:CTCF(display_short) psi-mi:try3_human(display_long)|uniprotkb:PRSS3(gene name)|psi-mi:PRSS3(display_short)|uniprotkb:PRSS4(gene name synonym)|uniprotkb:TRY3(gene name synonym)|uniprotkb:TRY4(gene name synonym)|uniprotkb:Trypsin III(gene name synonym)|uniprotkb:Brain trypsinogen(gene name synonym)|uniprotkb:Mesotrypsinogen(gene name synonym)|uniprotkb:Trypsin IV(gene name synonym)|uniprotkb:Serine protease 3(gene name synonym)|uniprotkb:Serine protease 4(gene name synonym)|uniprotkb:Mesotrypsin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477859|imex:IM-26985-311 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006556.1|refseq:NP_001177951.1|refseq:XP_016878357.1|dip:DIP-35252N|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006306"(DNA methylation)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0040030"(obsolete regulation of molecular function, epigenetic)|go:"GO:0043035"(chromatin insulator sequence binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071514"(genomic imprinting)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P49711|rcsb pdb:1X6H|rcsb pdb:2CT1|rcsb pdb:5K5H|rcsb pdb:5K5I|rcsb pdb:5K5J|rcsb pdb:5K5L|rcsb pdb:5KKQ|rcsb pdb:5T00|rcsb pdb:5T0U|rcsb pdb:5UND|rcsb pdb:5YEF|rcsb pdb:5YEG|rcsb pdb:5YEH|rcsb pdb:5YEL|rcsb pdb:6QNX|reactome:R-HSA-5617472|ensembl:ENSG00000102974(gene)|ensembl:ENST00000264010(transcript)|ensembl:ENST00000642819(transcript)|ensembl:ENST00000644753(transcript)|ensembl:ENST00000645699(transcript)|ensembl:ENST00000646076(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding) refseq:NP_002762.2|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|refseq:NP_001184026.2|refseq:NP_031369.2|refseq:NP_001184027.1|mint:P35030|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0007586"(digestion)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0031638"(zymogen activation)|go:"GO:0043542"(endothelial cell migration)|go:"GO:1904724"(tertiary granule lumen)|rcsb pdb:1H4W|rcsb pdb:2R9P|rcsb pdb:3L33|rcsb pdb:3L3T|rcsb pdb:3P92|rcsb pdb:3P95|rcsb pdb:4DG4|rcsb pdb:4U30|rcsb pdb:4U32|rcsb pdb:5C67|rcsb pdb:5JBT|rcsb pdb:5TP0|rcsb pdb:6BX8|rcsb pdb:6GFI|reactome:R-HSA-1462054|reactome:R-HSA-196741|reactome:R-HSA-6798695|reactome:R-HSA-6803157|interpro:IPR043504 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:hy9n/DVCzpfSi0EGigAjOZUvnIU9606 rogid:AEfz7orXeNoasizB5N76AkF4WMk9606 rigid:7P7Suf5ATQcl33HLwShLm7v71aU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P49711 uniprotkb:P84090 intact:EBI-932887|uniprotkb:Q53XI7|uniprotkb:B5MC38|uniprotkb:Q59EL8|ensembl:ENSP00000264010|ensembl:ENSP00000493495|ensembl:ENSP00000494408|ensembl:ENSP00000494538|ensembl:ENSP00000495348 intact:EBI-711389|uniprotkb:P70659|uniprotkb:Q14259|ensembl:ENSP00000451080|uniprotkb:B2R5H2 psi-mi:ctcf_human(display_long)|uniprotkb:CCCTC-binding factor(gene name synonym)|uniprotkb:CTCFL paralog(gene name synonym)|uniprotkb:11-zinc finger protein(gene name synonym)|uniprotkb:CTCF(gene name)|psi-mi:CTCF(display_short) psi-mi:erh_human(display_long)|uniprotkb:ERH(gene name)|psi-mi:ERH(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477859|imex:IM-26985-311 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006556.1|refseq:NP_001177951.1|refseq:XP_016878357.1|dip:DIP-35252N|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006306"(DNA methylation)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0040030"(obsolete regulation of molecular function, epigenetic)|go:"GO:0043035"(chromatin insulator sequence binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071514"(genomic imprinting)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P49711|rcsb pdb:1X6H|rcsb pdb:2CT1|rcsb pdb:5K5H|rcsb pdb:5K5I|rcsb pdb:5K5J|rcsb pdb:5K5L|rcsb pdb:5KKQ|rcsb pdb:5T00|rcsb pdb:5T0U|rcsb pdb:5UND|rcsb pdb:5YEF|rcsb pdb:5YEG|rcsb pdb:5YEH|rcsb pdb:5YEL|rcsb pdb:6QNX|reactome:R-HSA-5617472|ensembl:ENSG00000102974(gene)|ensembl:ENST00000264010(transcript)|ensembl:ENST00000642819(transcript)|ensembl:ENST00000644753(transcript)|ensembl:ENST00000645699(transcript)|ensembl:ENST00000646076(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding) ensembl:ENSG00000100632(gene)|ensembl:ENST00000557016(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006213"(pyrimidine nucleoside metabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0030496"(midbody)|go:"GO:0034709"(methylosome)|interpro:IPR000781(Enhancer of rudimentary)|interpro:IPR035912|mint:P84090|rcsb pdb:1W9G|rcsb pdb:2NML|rcsb pdb:7CNC|refseq:NP_004441.1|dip:DIP-42473N - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:hy9n/DVCzpfSi0EGigAjOZUvnIU9606 rogid:foMOmvZ9wQyH0rrzBB2YlQhrT0g9606 rigid:7P7Suf5ATQcl33HLwShLm7v71aU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P49711 uniprotkb:O95218 intact:EBI-932887|uniprotkb:Q53XI7|uniprotkb:B5MC38|uniprotkb:Q59EL8|ensembl:ENSP00000264010|ensembl:ENSP00000493495|ensembl:ENSP00000494408|ensembl:ENSP00000494538|ensembl:ENSP00000495348 intact:EBI-1051583|intact:EBI-1642120|intact:EBI-1163882|intact:EBI-1166395|uniprotkb:Q53GS3|uniprotkb:Q59F92|uniprotkb:Q5VV33|uniprotkb:Q8IXN6|uniprotkb:Q9UP63|uniprotkb:Q5VV34|uniprotkb:D3DQ75|ensembl:ENSP00000359958 psi-mi:ctcf_human(display_long)|uniprotkb:CCCTC-binding factor(gene name synonym)|uniprotkb:CTCFL paralog(gene name synonym)|uniprotkb:11-zinc finger protein(gene name synonym)|uniprotkb:CTCF(gene name)|psi-mi:CTCF(display_short) psi-mi:zrab2_human(display_long)|uniprotkb:ZRANB2(gene name)|psi-mi:ZRANB2(display_short)|uniprotkb:ZIS(gene name synonym)|uniprotkb:ZNF265(gene name synonym)|uniprotkb:Zinc finger protein 265(gene name synonym)|uniprotkb:Zinc finger, splicing(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477859|imex:IM-26985-311 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006556.1|refseq:NP_001177951.1|refseq:XP_016878357.1|dip:DIP-35252N|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006306"(DNA methylation)|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0040030"(obsolete regulation of molecular function, epigenetic)|go:"GO:0043035"(chromatin insulator sequence binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071514"(genomic imprinting)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P49711|rcsb pdb:1X6H|rcsb pdb:2CT1|rcsb pdb:5K5H|rcsb pdb:5K5I|rcsb pdb:5K5J|rcsb pdb:5K5L|rcsb pdb:5KKQ|rcsb pdb:5T00|rcsb pdb:5T0U|rcsb pdb:5UND|rcsb pdb:5YEF|rcsb pdb:5YEG|rcsb pdb:5YEH|rcsb pdb:5YEL|rcsb pdb:6QNX|reactome:R-HSA-5617472|ensembl:ENSG00000102974(gene)|ensembl:ENST00000264010(transcript)|ensembl:ENST00000642819(transcript)|ensembl:ENST00000644753(transcript)|ensembl:ENST00000645699(transcript)|ensembl:ENST00000646076(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding) refseq:NP_005446.2|refseq:NP_976225.1|ensembl:ENSG00000132485(gene)|ensembl:ENST00000370920(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR017337(Uncharacterised conserved protein UCP037956, zinc finger Ran-binding)|interpro:IPR036443|mint:O95218|rcsb pdb:1N0Z|rcsb pdb:2K1P|rcsb pdb:3G9Y - - comment:"author score: 34" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:hy9n/DVCzpfSi0EGigAjOZUvnIU9606 rogid:NSsZyRDwY5bF3I5OGvd1jGYTijY9606 rigid:7P7Suf5ATQcl33HLwShLm7v71aU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5TA45 uniprotkb:P18077 intact:EBI-748258|uniprotkb:Q5TA46|uniprotkb:Q5TA48|uniprotkb:Q5TA52|uniprotkb:Q5TA53|uniprotkb:Q5TA54|uniprotkb:Q7L3D7|uniprotkb:Q96HY1|uniprotkb:Q9BW36|uniprotkb:Q9H0F9|uniprotkb:Q9H8R5|uniprotkb:Q9HAA6|uniprotkb:Q9NWX9|uniprotkb:B4DM87|uniprotkb:A8K5S2|uniprotkb:B3KPR3|uniprotkb:G3V1S5|ensembl:ENSP00000413493 intact:EBI-353383|uniprotkb:Q08ES9|uniprotkb:Q9BVN7|ensembl:ENSP00000393393|ensembl:ENSP00000495672 psi-mi:int11_human(display_long)|uniprotkb:INTS11(gene name)|psi-mi:INTS11(display_short)|uniprotkb:CPSF3L(gene name synonym)|uniprotkb:Cleavage and polyadenylation-specific factor 3-like protein(gene name synonym)|uniprotkb:Protein related to CPSF subunits of 68 kDa(gene name synonym)|uniprotkb:RC68(gene name synonym) psi-mi:rl35a_human(display_long)|uniprotkb:RPL35A(gene name)|psi-mi:RPL35A(display_short)|uniprotkb:Cell growth-inhibiting gene 33 protein(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL33(gene name synonym)|uniprotkb:GIG33(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477835|imex:IM-26985-391 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060341.2|refseq:NP_001243392.1|refseq:NP_001243385.1|refseq:NP_001243389.1|refseq:NP_001243391.1|ensembl:ENSG00000127054(gene)|ensembl:ENST00000435064(transcript)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|go:"GO:0072562"(blood microparticle)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|interpro:IPR022712|interpro:IPR036866|interpro:IPR041897|mint:Q5TA45|rcsb pdb:5V8W|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 refseq:NP_000987.2|refseq:NP_001303240.1|ensembl:ENST00000647248(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001780(Ribosomal protein L35Ae)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR018266|interpro:IPR038661|mint:P18077|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|ensembl:ENSG00000182899(gene)|ensembl:ENST00000448864(transcript)|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:fKmUHJl/uR84eTlB28zhADznkXQ9606 rogid:fnUlL17LsiOp3lSkKNsoYO74IQQ9606 rigid:nCC+B/68QX8VEChV+MCOpNPDTXU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5TA45 uniprotkb:O95816 intact:EBI-748258|uniprotkb:Q5TA46|uniprotkb:Q5TA48|uniprotkb:Q5TA52|uniprotkb:Q5TA53|uniprotkb:Q5TA54|uniprotkb:Q7L3D7|uniprotkb:Q96HY1|uniprotkb:Q9BW36|uniprotkb:Q9H0F9|uniprotkb:Q9H8R5|uniprotkb:Q9HAA6|uniprotkb:Q9NWX9|uniprotkb:B4DM87|uniprotkb:A8K5S2|uniprotkb:B3KPR3|uniprotkb:G3V1S5|ensembl:ENSP00000413493 intact:EBI-355275|uniprotkb:Q08AS9|uniprotkb:Q6FID0|uniprotkb:B4DXE2|ensembl:ENSP00000359727|intact:EBI-11068407 psi-mi:int11_human(display_long)|uniprotkb:INTS11(gene name)|psi-mi:INTS11(display_short)|uniprotkb:CPSF3L(gene name synonym)|uniprotkb:Cleavage and polyadenylation-specific factor 3-like protein(gene name synonym)|uniprotkb:Protein related to CPSF subunits of 68 kDa(gene name synonym)|uniprotkb:RC68(gene name synonym) psi-mi:bag2_human(display_long)|uniprotkb:BAG2(gene name)|psi-mi:BAG2(display_short)|uniprotkb:Bcl-2-associated athanogene 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477835|imex:IM-26985-391 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060341.2|refseq:NP_001243392.1|refseq:NP_001243385.1|refseq:NP_001243389.1|refseq:NP_001243391.1|ensembl:ENSG00000127054(gene)|ensembl:ENST00000435064(transcript)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|go:"GO:0072562"(blood microparticle)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|interpro:IPR022712|interpro:IPR036866|interpro:IPR041897|mint:Q5TA45|rcsb pdb:5V8W|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 refseq:NP_004273.1|refseq:XP_011513301.1|refseq:XP_005249547.1|ensembl:ENSG00000112208(gene)|ensembl:ENST00000370693(transcript)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0019538"(protein metabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1901588"(dendritic microtubule)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|mint:O95816|reactome:R-HSA-3371453|refseq:XP_011513300.1 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:fKmUHJl/uR84eTlB28zhADznkXQ9606 rogid:nBGGBIQc/3P0mwp7N/XuTGLOrg89606 rigid:nCC+B/68QX8VEChV+MCOpNPDTXU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5TA45 uniprotkb:P05386 intact:EBI-748258|uniprotkb:Q5TA46|uniprotkb:Q5TA48|uniprotkb:Q5TA52|uniprotkb:Q5TA53|uniprotkb:Q5TA54|uniprotkb:Q7L3D7|uniprotkb:Q96HY1|uniprotkb:Q9BW36|uniprotkb:Q9H0F9|uniprotkb:Q9H8R5|uniprotkb:Q9HAA6|uniprotkb:Q9NWX9|uniprotkb:B4DM87|uniprotkb:A8K5S2|uniprotkb:B3KPR3|uniprotkb:G3V1S5|ensembl:ENSP00000413493 intact:EBI-354582|uniprotkb:A6NIB2|ensembl:ENSP00000346037 psi-mi:int11_human(display_long)|uniprotkb:INTS11(gene name)|psi-mi:INTS11(display_short)|uniprotkb:CPSF3L(gene name synonym)|uniprotkb:Cleavage and polyadenylation-specific factor 3-like protein(gene name synonym)|uniprotkb:Protein related to CPSF subunits of 68 kDa(gene name synonym)|uniprotkb:RC68(gene name synonym) psi-mi:rla1_human(display_long)|uniprotkb:RPLP1(gene name)|psi-mi:RPLP1(display_short)|uniprotkb:RRP1(gene name synonym)|uniprotkb:Large ribosomal subunit protein P1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477835|imex:IM-26985-391 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060341.2|refseq:NP_001243392.1|refseq:NP_001243385.1|refseq:NP_001243389.1|refseq:NP_001243391.1|ensembl:ENSG00000127054(gene)|ensembl:ENST00000435064(transcript)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|go:"GO:0072562"(blood microparticle)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|interpro:IPR022712|interpro:IPR036866|interpro:IPR041897|mint:Q5TA45|rcsb pdb:5V8W|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 refseq:NP_000994.1|refseq:NP_998890.1|ensembl:ENSG00000137818(gene)|ensembl:ENST00000260379(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0043021"(ribonucleoprotein complex binding)|interpro:IPR027534|interpro:IPR038716|mint:P05386|rcsb pdb:2LBF|rcsb pdb:4BEH|rcsb pdb:4V6X|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:fKmUHJl/uR84eTlB28zhADznkXQ9606 rogid:rHSXz4ZCJy+JH6OrjUgHiTK85mo9606 rigid:nCC+B/68QX8VEChV+MCOpNPDTXU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5TA45 uniprotkb:Q9NPA8 intact:EBI-748258|uniprotkb:Q5TA46|uniprotkb:Q5TA48|uniprotkb:Q5TA52|uniprotkb:Q5TA53|uniprotkb:Q5TA54|uniprotkb:Q7L3D7|uniprotkb:Q96HY1|uniprotkb:Q9BW36|uniprotkb:Q9H0F9|uniprotkb:Q9H8R5|uniprotkb:Q9HAA6|uniprotkb:Q9NWX9|uniprotkb:B4DM87|uniprotkb:A8K5S2|uniprotkb:B3KPR3|uniprotkb:G3V1S5|ensembl:ENSP00000413493 intact:EBI-719226|uniprotkb:B2RE52|intact:EBI-10972054|uniprotkb:G3V117|ensembl:ENSP00000429986 psi-mi:int11_human(display_long)|uniprotkb:INTS11(gene name)|psi-mi:INTS11(display_short)|uniprotkb:CPSF3L(gene name synonym)|uniprotkb:Cleavage and polyadenylation-specific factor 3-like protein(gene name synonym)|uniprotkb:Protein related to CPSF subunits of 68 kDa(gene name synonym)|uniprotkb:RC68(gene name synonym) psi-mi:eny2_human(display_long)|uniprotkb:Enhancer of yellow 2 transcription factor homolog(gene name synonym)|uniprotkb:DC6(orf name)|uniprotkb:ENY2(gene name)|psi-mi:ENY2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477835|imex:IM-26985-391 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060341.2|refseq:NP_001243392.1|refseq:NP_001243385.1|refseq:NP_001243389.1|refseq:NP_001243391.1|ensembl:ENSG00000127054(gene)|ensembl:ENST00000435064(transcript)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|go:"GO:0072562"(blood microparticle)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|interpro:IPR022712|interpro:IPR036866|interpro:IPR041897|mint:Q5TA45|rcsb pdb:5V8W|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 refseq:NP_001180486.1|refseq:NP_064574.1|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0061179"(negative regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0070390"(transcription export complex 2)|go:"GO:0071819"(DUBm complex)|interpro:IPR018783|interpro:IPR038212|mint:Q9NPA8|rcsb pdb:4DHX|go:"GO:0030374"(nuclear receptor coactivator activity)|reactome:R-HSA-3214847|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0015031"(protein transport)|go:"GO:0016578"(histone deubiquitination)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|ensembl:ENSG00000120533(gene)|ensembl:ENST00000521688(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II) - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:fKmUHJl/uR84eTlB28zhADznkXQ9606 rogid:CJmjqxLqgpxrqtvVVFcgxW5nloE9606 rigid:nCC+B/68QX8VEChV+MCOpNPDTXU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5TA45 uniprotkb:Q9NV88 intact:EBI-748258|uniprotkb:Q5TA46|uniprotkb:Q5TA48|uniprotkb:Q5TA52|uniprotkb:Q5TA53|uniprotkb:Q5TA54|uniprotkb:Q7L3D7|uniprotkb:Q96HY1|uniprotkb:Q9BW36|uniprotkb:Q9H0F9|uniprotkb:Q9H8R5|uniprotkb:Q9HAA6|uniprotkb:Q9NWX9|uniprotkb:B4DM87|uniprotkb:A8K5S2|uniprotkb:B3KPR3|uniprotkb:G3V1S5|ensembl:ENSP00000413493 intact:EBI-2866634|uniprotkb:O00224|uniprotkb:Q8TB16|uniprotkb:B7Z6M5|uniprotkb:B7Z560|ensembl:ENSP00000429065 psi-mi:int11_human(display_long)|uniprotkb:INTS11(gene name)|psi-mi:INTS11(display_short)|uniprotkb:CPSF3L(gene name synonym)|uniprotkb:Cleavage and polyadenylation-specific factor 3-like protein(gene name synonym)|uniprotkb:Protein related to CPSF subunits of 68 kDa(gene name synonym)|uniprotkb:RC68(gene name synonym) psi-mi:int9_human(display_long)|uniprotkb:INTS9(gene name)|psi-mi:INTS9(display_short)|uniprotkb:RC74(gene name synonym)|uniprotkb:Protein related to CPSF subunits of 74 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477835|imex:IM-26985-391 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060341.2|refseq:NP_001243392.1|refseq:NP_001243385.1|refseq:NP_001243389.1|refseq:NP_001243391.1|ensembl:ENSG00000127054(gene)|ensembl:ENST00000435064(transcript)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|go:"GO:0072562"(blood microparticle)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|interpro:IPR022712|interpro:IPR036866|interpro:IPR041897|mint:Q5TA45|rcsb pdb:5V8W|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 refseq:NP_001138631.1|refseq:NP_060720.2|refseq:NP_001166033.1|ensembl:ENSG00000104299(gene)|ensembl:ENST00000521022(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR022712|interpro:IPR027074|interpro:IPR036866|mint:Q9NV88|rcsb pdb:5V8W|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:fKmUHJl/uR84eTlB28zhADznkXQ9606 rogid:ShAqPc3dCrs+ixK2yO7PqGVSI/U9606 rigid:nCC+B/68QX8VEChV+MCOpNPDTXU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5TA45 uniprotkb:Q13232 intact:EBI-748258|uniprotkb:Q5TA46|uniprotkb:Q5TA48|uniprotkb:Q5TA52|uniprotkb:Q5TA53|uniprotkb:Q5TA54|uniprotkb:Q7L3D7|uniprotkb:Q96HY1|uniprotkb:Q9BW36|uniprotkb:Q9H0F9|uniprotkb:Q9H8R5|uniprotkb:Q9HAA6|uniprotkb:Q9NWX9|uniprotkb:B4DM87|uniprotkb:A8K5S2|uniprotkb:B3KPR3|uniprotkb:G3V1S5|ensembl:ENSP00000413493 intact:EBI-713684|uniprotkb:Q9BWH4|ensembl:ENSP00000219302 psi-mi:int11_human(display_long)|uniprotkb:INTS11(gene name)|psi-mi:INTS11(display_short)|uniprotkb:CPSF3L(gene name synonym)|uniprotkb:Cleavage and polyadenylation-specific factor 3-like protein(gene name synonym)|uniprotkb:Protein related to CPSF subunits of 68 kDa(gene name synonym)|uniprotkb:RC68(gene name synonym) psi-mi:ndk3_human(display_long)|uniprotkb:Nucleoside diphosphate kinase C(gene name synonym)|uniprotkb:nm23-H3(gene name synonym)|uniprotkb:DR-nm23(gene name synonym)|uniprotkb:NME3(gene name)|psi-mi:NME3(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477835|imex:IM-26985-391 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060341.2|refseq:NP_001243392.1|refseq:NP_001243385.1|refseq:NP_001243389.1|refseq:NP_001243391.1|ensembl:ENSG00000127054(gene)|ensembl:ENST00000435064(transcript)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|go:"GO:0072562"(blood microparticle)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR011108(RNA-metabolising metallo-beta-lactamase)|interpro:IPR022712|interpro:IPR036866|interpro:IPR041897|mint:Q5TA45|rcsb pdb:5V8W|rcsb pdb:7BFP|rcsb pdb:7BFQ|rcsb pdb:7CUN|reactome:R-HSA-6807505 ensembl:ENSG00000103024(gene)|ensembl:ENST00000219302(transcript)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|interpro:IPR023005|interpro:IPR034907|interpro:IPR036850|mint:Q13232|rcsb pdb:1ZS6|reactome:R-HSA-499943|refseq:NP_002504.2|dip:DIP-49960N - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:fKmUHJl/uR84eTlB28zhADznkXQ9606 rogid:/egrHNJSuCILf6NdwwchG9rUGqI9606 rigid:nCC+B/68QX8VEChV+MCOpNPDTXU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:P20719 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-8470697|uniprotkb:Q96CY6|intact:MINT-2801671|uniprotkb:O43367|uniprotkb:A4D179|ensembl:ENSP00000222726 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:hxa5_human(display_long)|uniprotkb:HOXA5(gene name)|psi-mi:HOXA5(display_short)|uniprotkb:HOX1C(gene name synonym)|uniprotkb:Homeobox protein Hox-1C(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) refseq:NP_061975.2|ensembl:ENSG00000106004(gene)|ensembl:ENST00000222726(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003016"(respiratory system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016477"(cell migration)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030878"(thyroid gland development)|go:"GO:0033599"(regulation of mammary gland epithelial cell proliferation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045639"(positive regulation of myeloid cell differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060435"(bronchiole development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060480"(lung goblet cell differentiation)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060535"(trachea cartilage morphogenesis)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0060638"(mesenchymal-epithelial cell signaling)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060764"(cell-cell signaling involved in mammary gland development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|mint:P20719 - - comment:mint|comment:homomint|function:Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Also binds to its own promoter. Binds specifically to the motif 5'-CYYNATTA[TG]Y-3'|comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:1W+oOoovKja439tdjkg3QjmSB9Q9606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:Q9NV06 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-7402939|uniprotkb:Q3MII9|uniprotkb:Q96JY7|uniprotkb:Q9NZX3|intact:MINT-4994304|uniprotkb:Q8NCH8|uniprotkb:Q8TC51|ensembl:ENSP00000484962 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:dca13_human(display_long)|uniprotkb:HSPC064(orf name)|uniprotkb:DCAF13(gene name)|psi-mi:DCAF13(display_short)|uniprotkb:WDSOF1(gene name synonym)|uniprotkb:WD repeat and SOF domain-containing protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) refseq:NP_056235.4|ensembl:ENSG00000164934(gene)|ensembl:ENST00000612750(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030054"(cell junction)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR007287(Sof1-like protein)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:Q9NV06|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-8951664 - - comment:mint|comment:homomint|function:Possible role in ribosomal RNA processing|comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:Ep2z6/V6/US0sXDqjqjpVqmf/zM9606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:O00570 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-2935583|ensembl:ENSP00000330218|uniprotkb:Q5W0Q1 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:sox1_human(display_long)|uniprotkb:SOX1(gene name)|psi-mi:SOX1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) ensembl:ENSG00000182968(gene)|ensembl:ENST00000330949(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0021521"(ventral spinal cord interneuron specification)|go:"GO:0021884"(forebrain neuron development)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1904936"(interneuron migration)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR031268|interpro:IPR036910|mint:O00570|go:"GO:0048713"(regulation of oligodendrocyte differentiation)|refseq:NP_005977.2 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:SICOjAD/I9cpyMAjYTlAd4Pf1yQ9606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:P09001 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-5325418|ensembl:ENSP00000264995|uniprotkb:Q6IBT2 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:rm03_human(display_long)|uniprotkb:Mitochondrial large ribosomal subunit protein uL3m(gene name synonym)|uniprotkb:MRPL3(gene name)|psi-mi:MRPL3(display_short)|uniprotkb:MRL3(gene name synonym)|uniprotkb:RPML3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) ensembl:ENSG00000114686(gene)|ensembl:ENST00000264995(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|interpro:IPR000597(Ribosomal protein L3)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR019926|mint:P09001|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|interpro:IPR019927|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:7OF7|refseq:NP_009139.1 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:JsDyyXQz9ZMCkRtp5TuL0PGYCjw9606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:P22695 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-1051424|uniprotkb:Q9BQ05|uniprotkb:B3KSN4|ensembl:ENSP00000268379 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:qcr2_human(display_long)|uniprotkb:Ubiquinol-cytochrome-c reductase complex core protein 2(gene name synonym)|uniprotkb:Core protein II(gene name synonym)|uniprotkb:Complex III subunit 2(gene name synonym)|uniprotkb:UQCRC2(gene name)|psi-mi:UQCRC2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) refseq:NP_003357.2|ensembl:ENSG00000140740(gene)|ensembl:ENST00000268379(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006508"(proteolysis)|go:"GO:0009060"(aerobic respiration)|go:"GO:0042493"|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001431(Peptidase M16, zinc-binding site)|interpro:IPR007863(Peptidase M16, C-terminal)|interpro:IPR011249(Metalloenzyme, LuxS/M16 peptidase-like, metal-binding)|interpro:IPR011765(Peptidase M16, N-terminal)|mint:P22695|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:++DmwaVpqzRyxFl7mh62L4ku4P09606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:Q8WUA2 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-2513119|ensembl:ENSP00000253329|uniprotkb:B2RD34|uniprotkb:Q7Z3Q5 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:ppil4_human(display_long)|uniprotkb:PPIL4(gene name)|psi-mi:PPIL4(display_short)|uniprotkb:Cyclophilin-like protein PPIL4(gene name synonym)|uniprotkb:Rotamase PPIL4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) go:"GO:1901407"(regulation of phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029000|interpro:IPR035538|interpro:IPR035542|interpro:IPR035979|mint:Q8WUA2|reactome:R-HSA-72163|go:"GO:0005829"(cytosol)|ensembl:ENSG00000131013(gene)|ensembl:ENST00000253329(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|refseq:NP_624311.1 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:kxM/VRcLUG5M5FAlHuuAKRBKrd89606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:Q8NDT2 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-726721|uniprotkb:Q6QE19|uniprotkb:Q9BV96|uniprotkb:A4QPG7|ensembl:ENSP00000454545 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:rb15b_human(display_long)|uniprotkb:RNA-binding motif protein 15B(gene name synonym)|uniprotkb:RBM15B(gene name)|psi-mi:RBM15B(display_short)|uniprotkb:OTT3(gene name synonym)|uniprotkb:One-twenty two protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) refseq:NP_037418.3|ensembl:ENSG00000259956(gene)|ensembl:ENST00000563281(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001510"(RNA methylation)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016607"(nuclear speck)|go:"GO:0036396"(RNA N6-methyladenosine methyltransferase complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR010912(Spen paralogue and orthologue C-terminal, metazoa)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012921(Spen paralogue and orthologue C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR034475|interpro:IPR034535|interpro:IPR034536|interpro:IPR035979|mint:Q8NDT2 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:uezua9bpM+Ru5qBYgb2VvhwpOo89606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:P40227 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:P48730 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-751621|uniprotkb:Q96KZ6|uniprotkb:Q9BTN5|uniprotkb:A2I2P2|ensembl:ENSP00000324464 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:kc1d_human(display_long)|uniprotkb:CSNK1D(gene name)|psi-mi:CSNK1D(display_short)|uniprotkb:HCKID(gene name synonym)|uniprotkb:Tau-protein kinase CSNK1D(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) refseq:NP_001884.2|refseq:NP_620693.1|dip:DIP-39735N|ensembl:ENSG00000141551(gene)|ensembl:ENST00000314028(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043005"(neuron projection)|go:"GO:0045296"(cadherin binding)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905426"(positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000052"(positive regulation of non-canonical Wnt signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P48730|rcsb pdb:3UYS|rcsb pdb:3UYT|rcsb pdb:3UZP|rcsb pdb:4HGT|rcsb pdb:4HNF|rcsb pdb:4KB8|rcsb pdb:4KBA|rcsb pdb:4KBC|rcsb pdb:4KBK|rcsb pdb:4TN6|rcsb pdb:4TW9|rcsb pdb:4TWC|rcsb pdb:5IH4|rcsb pdb:5IH5|rcsb pdb:5IH6|rcsb pdb:5MQV|rcsb pdb:5OKT|rcsb pdb:5W4W|rcsb pdb:6F1W|rcsb pdb:6F26|rcsb pdb:6GZM|rcsb pdb:6HMP|rcsb pdb:6HMR|rcsb pdb:6PXN|rcsb pdb:6PXO|rcsb pdb:6PXP|rcsb pdb:6RCG|rcsb pdb:6RCH|rcsb pdb:6RU6|rcsb pdb:6RU7|rcsb pdb:6RU8|reactome:R-HSA-204005|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-400253|reactome:R-HSA-5620912|reactome:R-HSA-6791226|reactome:R-HSA-8854518 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:Rz5aON17Bfduv29izmgHa/FR1/49606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:P82912 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-2371859|uniprotkb:Q969D7|uniprotkb:Q96GI3|uniprotkb:Q9BYC3|uniprotkb:B2RD52|ensembl:ENSP00000317376 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:rt11_human(display_long)|uniprotkb:MRPS11(gene name)|psi-mi:MRPS11(display_short)|uniprotkb:RPMS11(gene name synonym)|uniprotkb:Cervical cancer proto-oncogene 2 protein(gene name synonym)|uniprotkb:HCC2(orf name)|uniprotkb:Mitochondrial small ribosomal subunit protein uS11m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) refseq:NP_001308899.1|refseq:NP_001308901.1|refseq:NP_001308902.1|refseq:NP_001308903.1|refseq:NP_001308905.1|refseq:NP_073750.2|refseq:NP_789775.1|ensembl:ENSG00000181991(gene)|ensembl:ENST00000325844(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR001971(Ribosomal protein S11)|interpro:IPR018102|interpro:IPR036967|mint:P82912|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:aw3XzNBYY0igd4AUE1OQyfFn8pk9606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:O75319 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-719569|uniprotkb:Q6AI47|uniprotkb:Q9BWE3|uniprotkb:B2RCT8|ensembl:ENSP00000272444|uniprotkb:C9JYA6 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:dus11_human(display_long)|uniprotkb:Phosphatase that interacts with RNA/RNP complex 1(gene name synonym)|uniprotkb:Dual specificity protein phosphatase 11(gene name synonym)|uniprotkb:DUSP11(gene name)|psi-mi:DUSP11(display_short)|uniprotkb:PIR1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) refseq:NP_003575.2|ensembl:ENSG00000144048(gene)|ensembl:ENST00000272444(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0004651"(polynucleotide 5'-phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0016791"(phosphatase activity)|go:"GO:0045171"(intercellular bridge)|go:"GO:0098507"(polynucleotide 5' dephosphorylation)|go:"GO:0098519"(nucleotide phosphatase activity, acting on free nucleotides)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR029021|mint:O75319|rcsb pdb:4JMJ|rcsb pdb:4MBB|rcsb pdb:4NYH - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:6JgkXF0kxfddkDl+sU/A4v/4ObQ9606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:Q9P2J5 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-356077|uniprotkb:Q9NSE1|uniprotkb:A2RRR4|uniprotkb:B4DJ10|uniprotkb:Q2TU79|uniprotkb:A7E266|ensembl:ENSP00000377954 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:sylc_human(display_long)|uniprotkb:LARS1(gene name)|psi-mi:LARS1(display_short)|uniprotkb:KIAA1352(gene name synonym)|uniprotkb:LARS(gene name synonym)|uniprotkb:Leucyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) refseq:NP_064502.9|refseq:NP_001304893.1|refseq:NP_001304894.1|refseq:NP_057544.2|refseq:XP_011535958.1|ensembl:ENSG00000133706(gene)|ensembl:ENST00000394434(transcript)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004819"(glutamine-tRNA ligase activity)|go:"GO:0004823"(leucine-tRNA ligase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006425"(glutaminyl-tRNA aminoacylation)|go:"GO:0006429"(leucyl-tRNA aminoacylation)|go:"GO:0008361"(regulation of cell size)|go:"GO:0012505"(endomembrane system)|go:"GO:0016604"(nuclear body)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071233"(cellular response to leucine)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1990253"(cellular response to leucine starvation)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR004493(Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|mint:Q9P2J5|rcsb pdb:2WFD|rcsb pdb:6KID|rcsb pdb:6KIE|rcsb pdb:6KQY|rcsb pdb:6KR7|rcsb pdb:6LPF|rcsb pdb:6LR6|reactome:R-HSA-2408522|reactome:R-HSA-379716 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:nlK4kRCik2LLC3VNl0sryrLLnqA9606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:Q04726 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-1052057|uniprotkb:Q8IVV6|uniprotkb:Q8WVR2|uniprotkb:Q9HCM5|uniprotkb:B4DPT0|uniprotkb:F8W964|uniprotkb:E9PD64|ensembl:ENSP00000452871|uniprotkb:Q6PI57 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:tle3_human(display_long)|uniprotkb:Enhancer of split groucho-like protein 3(gene name synonym)|uniprotkb:TLE3(gene name)|psi-mi:TLE3(display_short)|uniprotkb:KIAA1547(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) refseq:NP_001098662.1|refseq:NP_005069.2|refseq:NP_065959.1|refseq:NP_001269908.1|refseq:NP_001269909.1|refseq:NP_001269910.1|refseq:NP_001269911.1|ensembl:ENSG00000140332(gene)|ensembl:ENST00000558939(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007165"(signal transduction)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:Q04726|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-3769402|reactome:R-HSA-4641265|reactome:R-HSA-9018519|dip:DIP-36666N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:lbsBYgdnyUWioqJ5euhotXA84Xg9606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:Q9NS86 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-2510837|ensembl:ENSP00000254770|uniprotkb:Q8TCQ3|uniprotkb:Q9BSR1|uniprotkb:B2R8D4|uniprotkb:Q6NSL4 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:lanc2_human(display_long)|uniprotkb:LANCL2(gene name)|psi-mi:LANCL2(display_short)|uniprotkb:GPR69B(gene name synonym)|uniprotkb:TASP(gene name synonym)|uniprotkb:Testis-specific adriamycin sensitivity protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) ensembl:ENSG00000132434(gene)|ensembl:ENST00000254770(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0009789"(positive regulation of abscisic acid-activated signaling pathway)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|interpro:IPR007822(Lanthionine synthetase C-like)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR020464|mint:Q9NS86|rcsb pdb:6WQ1|refseq:NP_061167.1 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:PkzdkGLvNrypmS0AERzZANWFPZ09606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:Q9HC62 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-714881|uniprotkb:Q8IW97|uniprotkb:Q96SR2|uniprotkb:Q9P2L5|uniprotkb:B4DQ42|intact:EBI-10966410|ensembl:ENSP00000296257 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:senp2_human(display_long)|uniprotkb:Sentrin/SUMO-specific protease SENP2(gene name synonym)|uniprotkb:SMT3-specific isopeptidase 2(gene name synonym)|uniprotkb:Axam2(gene name synonym)|uniprotkb:SENP2(gene name)|psi-mi:SENP2(display_short)|uniprotkb:KIAA1331(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) refseq:NP_067640.2|ensembl:ENSG00000163904(gene)|ensembl:ENST00000296257(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016926"(protein desumoylation)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031648"(protein destabilization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0051028"(mRNA transport)|go:"GO:0070139"(SUMO-specific endopeptidase activity)|interpro:IPR003653(Peptidase C48, SUMO/Sentrin/Ubl1)|interpro:IPR038765|mint:Q9HC62|rcsb pdb:1TGZ|rcsb pdb:1TH0|rcsb pdb:2IO0|rcsb pdb:2IO2|rcsb pdb:2IO3|rcsb pdb:3ZO5|rcsb pdb:5AEK|reactome:R-HSA-3065679|rcsb pdb:2IO1|dip:DIP-29254N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:zYThN+7SovDIV6Ly58vwds2CRZ49606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:P62987 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-357304|ensembl:ENSP00000388107|ensembl:ENSP00000396910|ensembl:ENSP00000470419|ensembl:ENSP00000470507|ensembl:ENSP00000471062|ensembl:ENSP00000471464|ensembl:ENSP00000471622|ensembl:ENSP00000472264|ensembl:ENSP00000472545|ensembl:ENSP00000473048|uniprotkb:P14793|uniprotkb:Q9BX98|uniprotkb:Q9UPK7|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62988|uniprotkb:Q29120|uniprotkb:Q6LBL4|uniprotkb:Q6LDU5|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9BWD6|uniprotkb:Q9UEF2|uniprotkb:Q9UEG1|uniprotkb:Q9UEK8 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:rl40_human(display_long)|uniprotkb:UBA52(gene name)|psi-mi:UBA52(display_short)|uniprotkb:UBCEP2(gene name synonym)|uniprotkb:CEP52(gene name synonym)|uniprotkb:Ubiquitin A-52 residue ribosomal protein fusion product 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) ensembl:ENSG00000221983(gene)|ensembl:ENST00000430157(transcript)|ensembl:ENST00000442744(transcript)|ensembl:ENST00000595158(transcript)|rcsb pdb:2MBH|rcsb pdb:2MJB|rcsb pdb:2MUR|ensembl:ENST00000595683(transcript)|ensembl:ENST00000596273(transcript)|rcsb pdb:2N3U|rcsb pdb:2N3V|rcsb pdb:2N3W|rcsb pdb:2NBD|ensembl:ENST00000596304(transcript)|rcsb pdb:2NBE|rcsb pdb:2RSU|rcsb pdb:4HJK|ensembl:ENST00000597451(transcript)|ensembl:ENST00000598780(transcript)|rcsb pdb:4JIO|rcsb pdb:4P4H|rcsb pdb:4PIG|ensembl:ENST00000599551(transcript)|ensembl:ENST00000599595(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|rcsb pdb:4PIH|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017085"(response to insecticide)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000626(Ubiquitin)|interpro:IPR001975(Ribosomal protein L40e)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038587|mint:P62987|rcsb pdb:2LJ5|rcsb pdb:4PIJ|rcsb pdb:4RF0|rcsb pdb:4S1Z|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:4XKL|rcsb pdb:5AJ0|rcsb pdb:5GO7|rcsb pdb:5GO8|rcsb pdb:5GOB|rcsb pdb:5GOC|rcsb pdb:5GOD|rcsb pdb:5GOG|rcsb pdb:5GOH|rcsb pdb:5GOI|rcsb pdb:5GOJ|rcsb pdb:5GOK|rcsb pdb:5HPK|rcsb pdb:5HPL|rcsb pdb:5HPS|rcsb pdb:5HPT|rcsb pdb:5J26|rcsb pdb:5J8P|rcsb pdb:5JBV|rcsb pdb:5JBY|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:4RF1|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7AY1|rcsb pdb:7BHP|rcsb pdb:7M3Q|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|rcsb pdb:6Z6N|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|reactome:R-HSA-1253288|reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-162588|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-1799339|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|reactome:R-HSA-192823|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-211733|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2173788|reactome:R-HSA-2173791|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2408557|reactome:R-HSA-2467813|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-168928|reactome:R-HSA-174048|reactome:R-HSA-349425|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6791226|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8863795|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-69231|reactome:R-HSA-8951664|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9633012|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9683683|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-975163|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-977225|reactome:R-HSA-983168|refseq:NP_001029102.1|refseq:NP_003324.1|refseq:NP_001307947.1|refseq:NP_001307948.1|refseq:NP_001307949.1|refseq:NP_001307946.1 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:x9O/Pbww4D28M1+hIj+p0xrUXgU9606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:Q9BYD2 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-726059|uniprotkb:Q9BSW8|uniprotkb:Q5SZR2|uniprotkb:B2RD99|ensembl:ENSP00000357823 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:rm09_human(display_long)|uniprotkb:MRPL9(gene name)|psi-mi:MRPL9(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein bL9m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) refseq:NP_113608.1|refseq:NP_001287662.1|ensembl:ENSG00000143436(gene)|ensembl:ENST00000368830(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020070|interpro:IPR036935|mint:Q9BYD2|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:JeHxoAdUc13d+0EnTCGBAa9rlVc9606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:P50990 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:P50750 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-1383449|uniprotkb:Q5JU24|uniprotkb:Q5JU25|uniprotkb:Q5U006|uniprotkb:Q96TF1|ensembl:ENSP00000362361 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:cdk9_human(display_long)|uniprotkb:CDK9(gene name)|psi-mi:CDK9(display_short)|uniprotkb:CDC2L4(gene name synonym)|uniprotkb:Cell division protein kinase 9(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PITALRE(gene name synonym)|uniprotkb:Cell division cycle 2-like protein kinase 4(gene name synonym)|uniprotkb:C-2K(gene name synonym)|uniprotkb:TAK(gene name synonym)|uniprotkb:Tat-associated kinase complex catalytic subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) refseq:NP_001252.1|dip:DIP-29016N|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000136807(gene)|ensembl:ENST00000373264(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P50750|rcsb pdb:1PF6|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:XSEmM4b5tp/WCJCJxnQYyP0stvM9606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:Q96SL8 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-2869737|uniprotkb:Q6ZMJ7|uniprotkb:A2RU72|ensembl:ENSP00000221665 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:fiz1_human(display_long)|uniprotkb:FIZ1(gene name)|psi-mi:FIZ1(display_short)|uniprotkb:ZNF798(gene name synonym)|uniprotkb:Zinc finger protein 798(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) refseq:NP_116225.2|refseq:XP_005259409.1|ensembl:ENSG00000179943(gene)|ensembl:ENST00000221665(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005634"(nucleus)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q96SL8 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:t8VQRjTuC7hYthJIEkWwUpf0U9M9606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:Q9C086 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-715611|ensembl:ENSP00000233331 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:in80b_human(display_long)|uniprotkb:PAP-1-associated protein 1(gene name synonym)|uniprotkb:High mobility group AT-hook 1-like 4(gene name synonym)|uniprotkb:INO80B(gene name)|psi-mi:INO80B(display_short)|uniprotkb:HMGA1L4(gene name synonym)|uniprotkb:PAPA1(gene name synonym)|uniprotkb:ZNHIT4(gene name synonym)|uniprotkb:Zinc finger HIT domain-containing protein 4(gene name synonym)|uniprotkb:IES2 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) refseq:NP_112578.2|interpro:IPR029523|mint:Q9C086|rcsb pdb:6HTS|reactome:R-HSA-5689603|reactome:R-HSA-5696394|interpro:IPR007529(Zinc finger, HIT-type)|ensembl:ENSG00000115274(gene)|ensembl:ENST00000233331(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0031011"(Ino80 complex)|go:"GO:0043044"|go:"GO:0046872"(metal ion binding)|interpro:IPR006880(PAPA-1-like conserved region) - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:4nwc9Jv4wjrMHJTe7kMJt1Z0nks9606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:Q15233 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-350527|ensembl:ENSP00000503233|uniprotkb:O00201|uniprotkb:P30807|uniprotkb:Q12786|uniprotkb:Q9BQC5|ensembl:ENSP00000276079|ensembl:ENSP00000362947|ensembl:ENSP00000406673|ensembl:ENSP00000410299|ensembl:ENSP00000415777|ensembl:ENSP00000503031|ensembl:ENSP00000504314|ensembl:ENSP00000504351|uniprotkb:D3DVV4|uniprotkb:B7Z4C2|uniprotkb:F5GYZ3 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:nono_human(display_long)|uniprotkb:NONO(gene name)|psi-mi:NONO(display_short)|uniprotkb:NRB54(gene name synonym)|uniprotkb:54 kDa nuclear RNA- and DNA-binding protein(gene name synonym)|uniprotkb:"p54(nrb)"(gene name synonym)|uniprotkb:55 kDa nuclear protein(gene name synonym)|uniprotkb:NMT55(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 52 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) refseq:NP_001138880.1|refseq:NP_001138881.1|refseq:NP_001138882.1|refseq:NP_031389.3|ensembl:ENSG00000147140(gene)|ensembl:ENST00000276079(transcript)|ensembl:ENST00000373841(transcript)|ensembl:ENST00000420903(transcript)|ensembl:ENST00000450092(transcript)|ensembl:ENST00000454976(transcript)|ensembl:ENST00000677274(transcript)|ensembl:ENST00000677446(transcript)|ensembl:ENST00000677612(transcript)|ensembl:ENST00000678231(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0042382"(paraspeckles)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034552|interpro:IPR035979|mint:Q15233|rcsb pdb:3SDE|rcsb pdb:5IFM|rcsb pdb:6WMZ|rcsb pdb:7LRQ|dip:DIP-29951N - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:5W3ooO4h0qh3GKO+WjDrLBhihHA9606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:Q7L2J0 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-2371983|uniprotkb:Q9NPD4|uniprotkb:B3KP86|uniprotkb:D6W5V7|ensembl:ENSP00000308546 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:mepce_human(display_long)|uniprotkb:MEPCE(gene name)|psi-mi:MEPCE(display_short)|uniprotkb:BCDIN3(gene name synonym)|uniprotkb:Bicoid-interacting protein 3 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) refseq:XP_011514712.1|refseq:NP_001181919.1|refseq:NP_001181920.1|refseq:NP_001181921.1|refseq:NP_062552.2|ensembl:ENSG00000146834(gene)|ensembl:ENST00000310512(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001510"(RNA methylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0008171"(O-methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0016073"(snRNA metabolic process)|go:"GO:0017069"(snRNA binding)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0040031"(snRNA modification)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1905382"(positive regulation of snRNA transcription by RNA polymerase II)|go:"GO:1990276"(RNA 5'-methyltransferase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR010675(Bicoid-interacting 3)|interpro:IPR024160|interpro:IPR025714|interpro:IPR029063|interpro:IPR039772|mint:Q7L2J0|rcsb pdb:5UNA|rcsb pdb:6DCB|rcsb pdb:6DCC - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:VGhJoO3FD7nsJPVSBsKuKsPJzEM9606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:Q9BZE4 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-1056249|uniprotkb:O95446|uniprotkb:Q9NVJ8|uniprotkb:B3KMC5|uniprotkb:B4DY13|uniprotkb:B7Z7A3|uniprotkb:Q5T3R8|ensembl:ENSP00000354040 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:gtpb4_human(display_long)|uniprotkb:GTPBP4(gene name)|psi-mi:GTPBP4(display_short)|uniprotkb:CRFG(gene name synonym)|uniprotkb:NOG1(gene name synonym)|uniprotkb:Chronic renal failure gene protein(gene name synonym)|uniprotkb:GTP-binding protein NGB(gene name synonym)|uniprotkb:Nucleolar GTP-binding protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) refseq:NP_036473.2|ensembl:ENSG00000107937(gene)|ensembl:ENST00000360803(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033342"(negative regulation of collagen binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006073(GTP1/OBG)|interpro:IPR010674(Nucleolar GTP-binding 1)|interpro:IPR012973(NOG, C-terminal)|interpro:IPR024926|interpro:IPR027417|interpro:IPR031167|interpro:IPR041623|mint:Q9BZE4|rcsb pdb:6LSS|rcsb pdb:6LU8 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:wTcBrIj6c27um4RnJH81grRgutc9606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:Q9H8H2 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-395655|uniprotkb:Q5K6N2|uniprotkb:Q5K6N3|uniprotkb:Q5K6N4|uniprotkb:Q5VZJ4|uniprotkb:Q5VZJ9|uniprotkb:Q96E91|uniprotkb:Q96NY2|uniprotkb:Q96SX5|uniprotkb:Q9H5K6|ensembl:ENSP00000361226|ensembl:ENSP00000361232 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:ddx31_human(display_long)|uniprotkb:DEAD box protein 31(gene name synonym)|uniprotkb:Helicain(gene name synonym)|uniprotkb:DDX31(gene name)|psi-mi:DDX31(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) refseq:NP_073616.6|refseq:NP_619526.1|ensembl:ENSG00000125485(gene)|ensembl:ENST00000372153(transcript)|ensembl:ENST00000372159(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|refseq:NP_001309269.1|refseq:NP_001309273.1|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR027417|mint:Q9H8H2|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR025313 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:HaC4SAnIvujAJVEcn/88Wij/zTM9606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:Q9Y6M1 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-1024419|intact:EBI-1059063|intact:EBI-1237206|uniprotkb:A0A4Z0|uniprotkb:B3FTN2|uniprotkb:B3FTN3|uniprotkb:B3FTN4|ensembl:ENSP00000371634 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:if2b2_human(display_long)|uniprotkb:IGF-II mRNA-binding protein 2(gene name synonym)|uniprotkb:Hepatocellular carcinoma autoantigen p62(gene name synonym)|uniprotkb:VICKZ family member 2(gene name synonym)|uniprotkb:IGF2BP2(gene name)|psi-mi:IGF2BP2(display_short)|uniprotkb:IMP2(gene name synonym)|uniprotkb:VICKZ2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) refseq:NP_001278801.1|refseq:NP_001278802.1|refseq:NP_001278803.1|refseq:NP_001278804.1|refseq:NP_001007226.1|refseq:NP_006539.3|ensembl:ENSG00000073792(gene)|ensembl:ENST00000382199(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007399"(nervous system development)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0045182"(translation regulator activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR028743|interpro:IPR034843|interpro:IPR035979|interpro:IPR036612|mint:Q9Y6M1|rcsb pdb:2CQH|rcsb pdb:6ROL|reactome:R-HSA-428359|dip:DIP-35539N - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:k45UViReMAxCv2cu7+tx+auevQc9606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:P62879 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-356942|uniprotkb:P54312|uniprotkb:P11016|uniprotkb:B3KPU1|ensembl:ENSP00000305260|ensembl:ENSP00000377501|ensembl:ENSP00000377503 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:gbb2_human(display_long)|uniprotkb:GNB2(gene name)|psi-mi:GNB2(display_short)|uniprotkb:Transducin beta chain 2(gene name synonym)|uniprotkb:G protein subunit beta-2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) refseq:NP_005264.2|go:"GO:0031682"(G-protein gamma-subunit binding)|go:"GO:0031982"(vesicle)|go:"GO:0044297"(cell body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051020"(GTPase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016346(Guanine nucleotide-binding protein, beta subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P62879|reactome:R-HSA-1296041|reactome:R-HSA-163359|reactome:R-HSA-202040|reactome:R-HSA-381676|reactome:R-HSA-392170|reactome:R-HSA-392451|reactome:R-HSA-392851|reactome:R-HSA-400042|reactome:R-HSA-4086398|reactome:R-HSA-416476|reactome:R-HSA-416482|reactome:R-HSA-418217|reactome:R-HSA-418555|reactome:R-HSA-418592|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-420092|reactome:R-HSA-428930|reactome:R-HSA-432040|reactome:R-HSA-456926|reactome:R-HSA-500657|reactome:R-HSA-6814122|reactome:R-HSA-8964315|reactome:R-HSA-8964616|reactome:R-HSA-9009391|reactome:R-HSA-9660821|reactome:R-HSA-997272|go:"GO:0016020"(membrane)|ensembl:ENSG00000172354(gene)|ensembl:ENST00000303210(transcript)|ensembl:ENST00000393924(transcript)|ensembl:ENST00000393926(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0007186"(G protein-coupled receptor signaling pathway) - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:dingPUxdpAhe7UMLquv0eqXNtUM9606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:P78371 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:Q9BXS5 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-541426|ensembl:ENSP00000291439|uniprotkb:Q4TTY5 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:ap1m1_human(display_long)|uniprotkb:Golgi adaptor HA1/AP1 adaptin mu-1 subunit(gene name synonym)|uniprotkb:Mu-adaptin 1(gene name synonym)|uniprotkb:AP-mu chain family member mu1A(gene name synonym)|uniprotkb:Mu1A-adaptin(gene name synonym)|uniprotkb:Clathrin coat assembly protein AP47(gene name synonym)|uniprotkb:Clathrin coat-associated protein AP47(gene name synonym)|uniprotkb:Adaptor protein complex AP-1 subunit mu-1(gene name synonym)|uniprotkb:Clathrin assembly protein complex 1 mu-1 medium chain 1(gene name synonym)|uniprotkb:AP1M1(gene name)|psi-mi:AP1M1(display_short)|uniprotkb:CLTNM(gene name synonym)|uniprotkb:Adaptor-related protein complex 1 subunit mu-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) refseq:NP_115882.1|ensembl:ENSG00000072958(gene)|ensembl:ENST00000291439(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030131"(clathrin adaptor complex)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032438"(melanosome organization)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0035615"(clathrin adaptor activity)|go:"GO:0035646"(endosome to melanosome transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001392(Clathrin adaptor, mu subunit)|interpro:IPR011012(Longin-like)|interpro:IPR018240|interpro:IPR028565|interpro:IPR036168|mint:Q9BXS5|reactome:R-HSA-164940|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-6798695|refseq:NP_001123996.1 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:B6OVovdusOdmvB0D+RIyhRRga2Q9606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:P51553 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-1210876|uniprotkb:Q9BUU5|uniprotkb:E9PDD5|ensembl:ENSP00000217901 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:idh3g_human(display_long)|uniprotkb:IDH3G(gene name)|psi-mi:IDH3G(display_short)|uniprotkb:Isocitric dehydrogenase subunit gamma(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit gamma"(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) refseq:NP_004126.1|refseq:NP_777358.1|ensembl:ENSG00000067829(gene)|ensembl:ENST00000217901(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|interpro:IPR024084|mint:P51553|rcsb pdb:5GRE|rcsb pdb:5GRF|rcsb pdb:5GRH|rcsb pdb:5GRI|rcsb pdb:5GRL|rcsb pdb:5YVT|rcsb pdb:6L57|rcsb pdb:6L59|rcsb pdb:7CE3|reactome:R-HSA-1268020|reactome:R-HSA-71403 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:CQ3xfzDzQreBvU2mRPSg5xUfjKY9606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:Q9Y4P3 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-2513719|ensembl:ENSP00000307260|uniprotkb:Q9UQE2 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:tbl2_human(display_long)|uniprotkb:TBL2(gene name)|psi-mi:TBL2(display_short)|uniprotkb:WBSCR13(gene name synonym)|uniprotkb:WS beta-transducin repeats protein(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 13 protein(gene name synonym)|uniprotkb:UNQ563/PRO1125(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) ensembl:ENSG00000106638(gene)|ensembl:ENST00000305632(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|interpro:IPR042410|mint:Q9Y4P3|refseq:NP_036585.1 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:K0mFwM08LEIAWO/zg4Irplaq9oM9606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:P62273 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-1054121|uniprotkb:P30054|uniprotkb:A8MZ73|ensembl:ENSP00000245458|ensembl:ENSP00000495033 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:rs29_human(display_long)|uniprotkb:RPS29(gene name)|psi-mi:RPS29(display_short)|uniprotkb:Small ribosomal subunit protein uS14(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) refseq:NP_001023.1|refseq:NP_001025172.1|ensembl:ENSG00000213741(gene)|ensembl:ENST00000245458(transcript)|ensembl:ENST00000556230(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|interpro:IPR001209(Ribosomal protein S14)|interpro:IPR018271|interpro:IPR039744|interpro:IPR043140|mint:P62273|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:vMgvFs6gwidbpv837yH2u0sSIAU9606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:Q969Q0 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-2877705|ensembl:ENSP00000346012|uniprotkb:Q3B7A5 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:rl36l_human(display_long)|uniprotkb:RPL36AL(gene name)|psi-mi:RPL36AL(display_short)|uniprotkb:Large ribosomal subunit protein eL42-like(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) ensembl:ENSG00000165502(gene)|ensembl:ENST00000298289(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR000552(Ribosomal protein L44e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|mint:Q969Q0|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-9633012|refseq:NP_000992.1 - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:+jT5oFy79StEavkvHz6j/36g/qg9606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:Q99832 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422 - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:P09960 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-721089|uniprotkb:Q6IAT6|uniprotkb:Q9UCT7|uniprotkb:B4DNQ9|uniprotkb:F8VV40|ensembl:ENSP00000228740 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:lkha4_human(display_long)|uniprotkb:"Leukotriene A(4) hydrolase"(gene name synonym)|uniprotkb:LTA4H(gene name)|psi-mi:LTA4H(display_short)|uniprotkb:LTA4(gene name synonym)|uniprotkb:Tripeptide aminopeptidase LTA4H(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) refseq:NP_001243573.1|refseq:NP_000886.1|refseq:NP_001243572.1|refseq:XP_005268928.1|ensembl:ENSG00000111144(gene)|ensembl:ENST00000228740(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0004301"(epoxide hydrolase activity)|go:"GO:0004463"(leukotriene-A4 hydrolase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019370"(leukotriene biosynthetic process)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0044267"(cellular protein metabolic process)|go:"GO:0070006"(metalloaminopeptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001930(Peptidase M1, membrane alanine aminopeptidase)|interpro:IPR012777(Leukotriene A-4 hydrolase/aminopeptidase)|interpro:IPR014782(Peptidase M1, membrane alanine aminopeptidase, N-terminal)|interpro:IPR015211(Peptidase M1, leukotriene A4 hydrolase, aminopeptidase C-terminal)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027268|interpro:IPR034015|interpro:IPR038502|interpro:IPR042097|mint:P09960|rcsb pdb:1GW6|rcsb pdb:1H19|rcsb pdb:1HS6|rcsb pdb:1SQM|rcsb pdb:2R59|rcsb pdb:2VJ8|rcsb pdb:3B7R|rcsb pdb:3B7S|rcsb pdb:3B7T|rcsb pdb:3B7U|rcsb pdb:3CHO|rcsb pdb:3CHP|rcsb pdb:3CHQ|rcsb pdb:3CHR|rcsb pdb:3CHS|rcsb pdb:3FH5|rcsb pdb:3FH7|rcsb pdb:3FH8|rcsb pdb:3FHE|rcsb pdb:3FTS|rcsb pdb:3FTU|rcsb pdb:3FTV|rcsb pdb:3FTW|go:"GO:0045148"(tripeptide aminopeptidase activity)|rcsb pdb:3FTX|rcsb pdb:3FTY|rcsb pdb:3FTZ|rcsb pdb:3FU0|rcsb pdb:3FU3|rcsb pdb:3FU5|rcsb pdb:3FU6|rcsb pdb:3FUD|rcsb pdb:3FUE|rcsb pdb:3FUF|rcsb pdb:3FUH|rcsb pdb:3FUI|rcsb pdb:3FUJ|rcsb pdb:3FUK|rcsb pdb:3FUL|rcsb pdb:3FUM|rcsb pdb:3FUN|rcsb pdb:3U9W|rcsb pdb:4DPR|rcsb pdb:4L2L|rcsb pdb:4MKT|rcsb pdb:4MS6|rcsb pdb:4R7L|rcsb pdb:4RSY|rcsb pdb:4RVB|rcsb pdb:5AEN|rcsb pdb:5BPP|rcsb pdb:5FWQ|rcsb pdb:5N3W|rcsb pdb:5NI2|rcsb pdb:5NI4|rcsb pdb:5NI6|rcsb pdb:5NIA|rcsb pdb:5NID|rcsb pdb:5NIE|rcsb pdb:6ENB|rcsb pdb:6ENC|rcsb pdb:6END|rcsb pdb:6O5H|rcsb pdb:7AUZ|rcsb pdb:7AV0|rcsb pdb:7AV1|rcsb pdb:7AV2|reactome:R-HSA-2142691|reactome:R-HSA-6798695|reactome:R-HSA-9018676|reactome:R-HSA-9018681|reactome:R-HSA-9018896|reactome:R-HSA-9020265|reactome:R-HSA-9023661 - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:Qu84Rla6vl6zFvgcVCzHOa8mUbA9606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:P06493 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-444308|ensembl:ENSP00000378699|uniprotkb:O60764|uniprotkb:C9J497|uniprotkb:A8K7C4 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:cdk1_human(display_long)|uniprotkb:p34 protein kinase(gene name synonym)|uniprotkb:Cell division protein kinase 1(gene name synonym)|uniprotkb:CDK1(gene name)|psi-mi:CDK1(display_short)|uniprotkb:CDC2(gene name synonym)|uniprotkb:Cell division control protein 2 homolog(gene name synonym)|uniprotkb:CDC28A(gene name synonym)|uniprotkb:CDKN1(gene name synonym)|uniprotkb:P34CDC2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007344"(pronuclear fusion)|go:"GO:0007569"(cell aging)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0014038"(regulation of Schwann cell differentiation)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0014075"(response to amine)|go:"GO:0014823"(response to activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0030332"(cyclin binding)|go:"GO:0030496"(midbody)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0035173"(histone kinase activity)|go:"GO:0006260"(DNA replication)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046688"(response to copper ion)|go:"GO:0048511"(rhythmic process)|go:"GO:0048678"(response to axon injury)|go:"GO:0051301"(cell division)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0042493"|go:"GO:0072686"(mitotic spindle)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0097125"(cyclin B1-CDK1 complex)|go:"GO:0097472"(cyclin-dependent protein kinase activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1905448"(positive regulation of mitochondrial ATP synthesis coupled electron transport)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P06493|rcsb pdb:1LC9|rcsb pdb:4Y72|rcsb pdb:4YC3|rcsb pdb:4YC6|rcsb pdb:5HQ0|rcsb pdb:5LQF|rcsb pdb:6GU2|rcsb pdb:6GU3|rcsb pdb:6GU4|rcsb pdb:6GU6|go:"GO:0042752"(regulation of circadian rhythm)|rcsb pdb:6GU7|rcsb pdb:6TWN|reactome:R-HSA-110056|reactome:R-HSA-113507|reactome:R-HSA-1362300|reactome:R-HSA-162658|reactome:R-HSA-170145|reactome:R-HSA-174048|reactome:R-HSA-174184|reactome:R-HSA-176408|reactome:R-HSA-176412|reactome:R-HSA-176417|reactome:R-HSA-2299718|reactome:R-HSA-2465910|reactome:R-HSA-2500257|reactome:R-HSA-2514853|reactome:R-HSA-2565942|reactome:R-HSA-2980767|reactome:R-HSA-2995383|reactome:R-HSA-3301854|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-4419969|reactome:R-HSA-5620912|reactome:R-HSA-5687128|reactome:R-HSA-5689896|reactome:R-HSA-6804114|reactome:R-HSA-6804757|reactome:R-HSA-68875|reactome:R-HSA-69205|reactome:R-HSA-69273|reactome:R-HSA-69478|reactome:R-HSA-75035|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8878166|ensembl:ENSG00000170312(gene)|ensembl:ENST00000395284(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001618"(virus receptor activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|refseq:NP_001777.1|refseq:NP_203698.1|refseq:XP_005270360.1|refseq:NP_001307847.1|dip:DIP-35N - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:8geyXVp0Rpm8sG8I76/XgWsZ4JA9606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:P47985 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-1045520|uniprotkb:Q6NVX5|uniprotkb:Q9UPH2|uniprotkb:A8K519|ensembl:ENSP00000306397 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:ucri_human(display_long)|uniprotkb:Ubiquinol-cytochrome c reductase iron-sulfur subunit(gene name synonym)|uniprotkb:Rieske iron-sulfur protein(gene name synonym)|uniprotkb:Complex III subunit 5(gene name synonym)|uniprotkb:Rieske protein UQCRFS1(gene name synonym)|uniprotkb:UQCRFS1(gene name)|psi-mi:UQCRFS1(display_short)|uniprotkb:Cytochrome b-c1 complex subunit 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) refseq:NP_005994.2|ensembl:ENSG00000169021(gene)|ensembl:ENST00000304863(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005750"(mitochondrial respiratory chain complex III)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0008121"(ubiquinol-cytochrome-c reductase activity)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0034551"(mitochondrial respiratory chain complex III assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|interpro:IPR004192(Ubiquinol cytochrome reductase transmembrane region)|interpro:IPR005805(Rieske iron-sulphur protein, C-terminal)|interpro:IPR006317(Ubiquinol-cytochrome c reductase, iron-sulphur subunit)|interpro:IPR011070(Globular protein, non-globular alpha/beta subunit)|interpro:IPR014349(Rieske iron-sulphur protein)|interpro:IPR015248(Ubiquinol-cytochrome c reductase 8 kDa, N-terminal)|interpro:IPR017941|interpro:IPR036922|interpro:IPR037008|mint:P47985|rcsb pdb:5XTE|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105 - - comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:uBXz1yLEfiKg0/8rti+BnA5G9Nk9606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:Q9NY93 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-372376|uniprotkb:Q9H9I8|intact:EBI-1051948|uniprotkb:Q6IAE2|uniprotkb:A4D2K9|ensembl:ENSP00000258772|uniprotkb:C9JV95 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:ddx56_human(display_long)|uniprotkb:DDX56(gene name)|psi-mi:DDX56(display_short)|uniprotkb:DDX21(gene name synonym)|uniprotkb:DEAD box protein 56(gene name synonym)|uniprotkb:ATP-dependent 61 kDa nucleolar RNA helicase(gene name synonym)|uniprotkb:DEAD box protein 21(gene name synonym)|uniprotkb:NOH61(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) refseq:NP_061955.1|ensembl:ENSG00000136271(gene)|ensembl:ENST00000258772(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q9NY93|refseq:NP_001244118.1 - - comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:Pfa1hEJ7HnBZtSO4aZ2xRixpldc9606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:P43034 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-720620|uniprotkb:Q8WZ88|uniprotkb:Q8WZ89|uniprotkb:B2R7Q7|ensembl:ENSP00000380378|ensembl:ENSP00000501969|ensembl:ENSP00000502031|ensembl:ENSP00000502577|ensembl:ENSP00000502735|ensembl:ENSP00000502843 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:lis1_human(display_long)|uniprotkb:PAF acetylhydrolase 45 kDa subunit(gene name synonym)|uniprotkb:PAF-AH alpha(gene name synonym)|uniprotkb:Lissencephaly-1 protein(gene name synonym)|uniprotkb:PAFAH1B1(gene name)|psi-mi:PAFAH1B1(display_short)|uniprotkb:LIS1(gene name synonym)|uniprotkb:MDCR(gene name synonym)|uniprotkb:PAFAHA(gene name synonym)|uniprotkb:MDS(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) refseq:NP_000421.1|ensembl:ENSG00000007168(gene)|ensembl:ENST00000397195(transcript)|ensembl:ENST00000675202(transcript)|ensembl:ENST00000675331(transcript)|ensembl:ENST00000675390(transcript)|ensembl:ENST00000676098(transcript)|ensembl:ENST00000676188(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000235"(astral microtubule)|go:"GO:0000776"(kinetochore)|refseq:XP_016880188.1|refseq:XP_016880189.1|refseq:XP_016880190.1|dip:DIP-35691N|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0001675"(acrosome assembly)|go:"GO:0001764"(neuron migration)|go:"GO:0001961"(positive regulation of cytokine-mediated signaling pathway)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007097"(nuclear migration)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007281"(germ cell development)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007611"(learning or memory)|go:"GO:0008017"(microtubule binding)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0008201"(heparin binding)|go:"GO:0008247"(1-alkyl-2-acetylglycerophosphocholine esterase complex)|go:"GO:0009306"(protein secretion)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0017145"(stem cell division)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0021540"(corpus callosum morphogenesis)|go:"GO:0021766"(hippocampus development)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031514"(motile cilium)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032420"(stereocilium)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0036035"(osteoclast development)|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042249"(establishment of planar polarity of embryonic epithelium)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0045202"(synapse)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046469"(platelet activating factor metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051661"(maintenance of centrosome location)|go:"GO:0060117"(auditory receptor cell development)|go:"GO:0034452"(dynactin binding)|interpro:IPR017252(Dynein regulator)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR037190|mint:P43034|rcsb pdb:7MT1|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9648025|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070840"(dynein complex binding)|go:"GO:0090102"(cochlea development)|go:"GO:0090176"(microtubule cytoskeleton organization involved in establishment of planar polarity)|go:"GO:0090724"(central region of growth cone)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000574"(obsolete regulation of microtubule motor activity)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR015943(WD40/YVTN repeat-like) - - comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:CgijDhrO703mGYXvJ44BgQJfVgM9606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:P42765 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-2852639|uniprotkb:Q9BUT6|ensembl:ENSP00000285093 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:thim_human(display_long)|uniprotkb:Acetyl-CoA acetyltransferase(gene name synonym)|uniprotkb:Acyl-CoA hydrolase, mitochondrial(gene name synonym)|uniprotkb:ACAA2(gene name)|psi-mi:ACAA2(display_short)|uniprotkb:Acetyl-CoA acyltransferase(gene name synonym)|uniprotkb:Beta-ketothiolase(gene name synonym)|uniprotkb:Mitochondrial 3-oxoacyl-CoA thiolase(gene name synonym)|uniprotkb:T1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) refseq:NP_006102.2|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|mint:P42765|rcsb pdb:4C2J|rcsb pdb:4C2K|reactome:R-HSA-77289|interpro:IPR020613|ensembl:ENSG00000167315(gene)|ensembl:ENST00000285093(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003985"(acetyl-CoA C-acetyltransferase activity)|go:"GO:0003986"(acetyl-CoA hydrolase activity)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0016290"(palmitoyl-CoA hydrolase activity)|go:"GO:0047617"(acyl-CoA hydrolase activity)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0102991"(myristoyl-CoA hydrolase activity)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1902109"(negative regulation of mitochondrial membrane permeability involved in apoptotic process)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610 - - comment:"author score: 27" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:TJMFLcEB5eKz36plSuUiteAJN9g9606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:Q96T76 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-1044169|uniprotkb:Q9BYS9|uniprotkb:Q17RZ8|uniprotkb:Q5T455|uniprotkb:Q66K82|uniprotkb:Q7L4W8|uniprotkb:Q969Z1|uniprotkb:Q96DF1|uniprotkb:Q96MR1|uniprotkb:Q96RK5|uniprotkb:Q96SK1|uniprotkb:Q9BUE2|ensembl:ENSP00000359818|ensembl:ENSP00000412698|uniprotkb:D3DR55|uniprotkb:B0QZ75|uniprotkb:B3KPE5|uniprotkb:B4DQX2|uniprotkb:B4E2I3|uniprotkb:F8W9Y2 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:mms19_human(display_long)|uniprotkb:MMS19(gene name)|psi-mi:MMS19(display_short)|uniprotkb:MMS19L(gene name synonym)|uniprotkb:MMS19-like protein(gene name synonym)|uniprotkb:MET18 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) ensembl:ENSG00000155229(gene)|ensembl:ENST00000370782(transcript)|ensembl:ENST00000438925(transcript)|go:"GO:0000160"(phosphorelay signal transduction system)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024687|interpro:IPR029240|interpro:IPR039920|mint:Q96T76|reactome:R-HSA-2564830|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0009725"(response to hormone)|go:"GO:0016020"(membrane)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0019899"(enzyme binding)|refseq:NP_071757.4|refseq:NP_001276332.1|refseq:NP_001276333.1|refseq:NP_001276334.1|refseq:NP_001317057.1|refseq:XP_016872013.1 - - comment:"author score: 50" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:sujw9MQiwau6A0dumVM7gXVMGjE9606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:Q9Y3D0 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-744045|ensembl:ENSP00000387471 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:cia2b_human(display_long)|uniprotkb:CIAO2B(gene name)|psi-mi:CIAO2B(display_short)|uniprotkb:CIAB(gene name synonym)|uniprotkb:FAM96B(gene name synonym)|uniprotkb:MIP18(gene name synonym)|uniprotkb:MSS19-interacting protein of 18 kDa(gene name synonym)|uniprotkb:Mitotic spindle-associated MMXD complex subunit MIP18(gene name synonym)|uniprotkb:Protein FAM96B(gene name synonym)|uniprotkb:CGI-128(orf name)|uniprotkb:HSPC118(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) refseq:NP_057146.1|ensembl:ENSG00000166595(gene)|ensembl:ENST00000422424(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030496"(midbody)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|interpro:IPR002744(Protein of unknown function DUF59)|interpro:IPR034904|interpro:IPR039796|mint:Q9Y3D0|reactome:R-HSA-2564830 - - comment:"author score: 56" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:6LfOUjTAKuEjop3XVyyxx6c4Wl09606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O76071 uniprotkb:Q9H5X1 intact:EBI-725145|uniprotkb:A0MNN9|uniprotkb:Q53FM5|ensembl:ENSP00000418287 intact:EBI-752069|uniprotkb:B2R5F8|uniprotkb:A6NKS1|uniprotkb:B7Z8Z5|ensembl:ENSP00000300030 psi-mi:ciao1_human(display_long)|uniprotkb:WD repeat-containing protein 39(gene name synonym)|uniprotkb:CIAO1(gene name)|psi-mi:CIAO1(display_short)|uniprotkb:WDR39(gene name synonym)|uniprotkb:CIA1(gene name synonym) psi-mi:cia2a_human(display_long)|uniprotkb:CIAO2A(gene name)|psi-mi:CIAO2A(display_short)|uniprotkb:CIA2A(gene name synonym)|uniprotkb:FAM96A(gene name synonym)|uniprotkb:MIP18 family protein FAM96A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477658|imex:IM-26985-81 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004795.1|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR028608|interpro:IPR036322|mint:O76071|rcsb pdb:3FM0|reactome:R-HSA-2564830|ensembl:ENSG00000144021(gene)|ensembl:ENST00000488633(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0071817"(MMXD complex)|go:"GO:0097361"(CIA complex)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer) refseq:NP_001014812.1|refseq:NP_115607.1|refseq:NP_001276037.1|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|go:"GO:0106035"(protein maturation by [4Fe-4S] cluster transfer)|interpro:IPR002744(Protein of unknown function DUF59)|interpro:IPR034904|interpro:IPR039796|mint:Q9H5X1|rcsb pdb:2M5H|ensembl:ENSG00000166797(gene)|ensembl:ENST00000300030(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0097361"(CIA complex)|rcsb pdb:3UX2|rcsb pdb:3UX3 - - comment:"author score: 65" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Lm4qlRM/4M+yz9miSayiAnBh5Dk9606 rogid:ENTDOcazbYwVYob25el/jMB5ah09606 rigid:3BslJqGW3jd1X6tmIUKIiglxK04 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H816 uniprotkb:Q6PEV8 intact:EBI-3508943|uniprotkb:Q9H9E5|ensembl:ENSP00000498042 intact:EBI-4280426|uniprotkb:Q8WVP6|uniprotkb:Q96AV3|ensembl:ENSP00000417581 psi-mi:dcr1b_human(display_long)|uniprotkb:DCLRE1B(gene name)|psi-mi:DCLRE1B(display_short)|uniprotkb:SNM1B(gene name synonym)|uniprotkb:DNA cross-link repair 1B protein(gene name synonym)|uniprotkb:SNM1 homolog B(gene name synonym)|uniprotkb:Beta-lactamase DCLRE1B(gene name synonym) psi-mi:f199x_human(display_long)|uniprotkb:FAM199X(gene name)|psi-mi:FAM199X(display_short)|uniprotkb:CXorf39(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478024|imex:IM-26985-315 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0010833"(telomere maintenance via telomere lengthening)|refseq:NP_073747.1|refseq:NP_001306876.1|ensembl:ENSG00000118655(gene)|ensembl:ENST00000650450(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0016604"(nuclear body)|go:"GO:0031627"(telomeric loop formation)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0035312"(5'-3' exodeoxyribonuclease activity)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR011084(DNA repair metallo-beta-lactamase)|interpro:IPR036866|mint:Q9H816|rcsb pdb:3BUA|rcsb pdb:5AHO|rcsb pdb:7A1F|go:"GO:0016233"(telomere capping)|rcsb pdb:7B2X|rcsb pdb:7B9B|reactome:R-HSA-6783310|dip:DIP-42669N refseq:NP_997201.1|refseq:XP_005262136.1|ensembl:ENSG00000123575(gene)|ensembl:ENST00000493442(transcript)|interpro:IPR029672|mint:Q6PEV8 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:bl5L/CwIn5xCj46ElzYxmctQgjU9606 rogid:yy2plvcV+J7AM2flWIBz8+uEzZ09606 rigid:zMIYFynrQzebPAr9EISacmVOXWQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H816 uniprotkb:Q71UM5 intact:EBI-3508943|uniprotkb:Q9H9E5|ensembl:ENSP00000498042 intact:EBI-355126|uniprotkb:Q9BTJ1|ensembl:ENSP00000331019 psi-mi:dcr1b_human(display_long)|uniprotkb:DCLRE1B(gene name)|psi-mi:DCLRE1B(display_short)|uniprotkb:SNM1B(gene name synonym)|uniprotkb:DNA cross-link repair 1B protein(gene name synonym)|uniprotkb:SNM1 homolog B(gene name synonym)|uniprotkb:Beta-lactamase DCLRE1B(gene name synonym) psi-mi:rs27l_human(display_long)|uniprotkb:RPS27L(gene name)|psi-mi:RPS27L(display_short)|uniprotkb:Small ribosomal subunit protein eS27-like(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478024|imex:IM-26985-315 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0010833"(telomere maintenance via telomere lengthening)|refseq:NP_073747.1|refseq:NP_001306876.1|ensembl:ENSG00000118655(gene)|ensembl:ENST00000650450(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0016604"(nuclear body)|go:"GO:0031627"(telomeric loop formation)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0035312"(5'-3' exodeoxyribonuclease activity)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR011084(DNA repair metallo-beta-lactamase)|interpro:IPR036866|mint:Q9H816|rcsb pdb:3BUA|rcsb pdb:5AHO|rcsb pdb:7A1F|go:"GO:0016233"(telomere capping)|rcsb pdb:7B2X|rcsb pdb:7B9B|reactome:R-HSA-6783310|dip:DIP-42669N refseq:NP_057004.1|ensembl:ENSG00000185088(gene)|ensembl:ENST00000330964(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0006412"(translation)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008494"(translation activator activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046872"(metal ion binding)|interpro:IPR000592(Ribosomal protein S27e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR023407|mint:Q71UM5|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:bl5L/CwIn5xCj46ElzYxmctQgjU9606 rogid:OVIAlDF6dN3DxLZgQFrFl8r0Z0I9606 rigid:zMIYFynrQzebPAr9EISacmVOXWQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H816 uniprotkb:O95073 intact:EBI-3508943|uniprotkb:Q9H9E5|ensembl:ENSP00000498042 intact:EBI-1059030|intact:EBI-2350009|uniprotkb:Q8N4S5|ensembl:ENSP00000420405 psi-mi:dcr1b_human(display_long)|uniprotkb:DCLRE1B(gene name)|psi-mi:DCLRE1B(display_short)|uniprotkb:SNM1B(gene name synonym)|uniprotkb:DNA cross-link repair 1B protein(gene name synonym)|uniprotkb:SNM1 homolog B(gene name synonym)|uniprotkb:Beta-lactamase DCLRE1B(gene name synonym) psi-mi:fsbp_human(display_long)|uniprotkb:FSBP(gene name)|psi-mi:FSBP(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478024|imex:IM-26985-315 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0010833"(telomere maintenance via telomere lengthening)|refseq:NP_073747.1|refseq:NP_001306876.1|ensembl:ENSG00000118655(gene)|ensembl:ENST00000650450(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0016604"(nuclear body)|go:"GO:0031627"(telomeric loop formation)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0035312"(5'-3' exodeoxyribonuclease activity)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR011084(DNA repair metallo-beta-lactamase)|interpro:IPR036866|mint:Q9H816|rcsb pdb:3BUA|rcsb pdb:5AHO|rcsb pdb:7A1F|go:"GO:0016233"(telomere capping)|rcsb pdb:7B2X|rcsb pdb:7B9B|reactome:R-HSA-6783310|dip:DIP-42669N refseq:NP_001243070.1|refseq:NP_001192191.1|interpro:IPR042383|mint:O95073|ensembl:ENSG00000265817(gene)|ensembl:ENST00000481490(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0042802"(identical protein binding)|interpro:IPR028002 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:bl5L/CwIn5xCj46ElzYxmctQgjU9606 rogid:+oyi0NX4VFriXU9f1xpS7UMTPcU9606 rigid:zMIYFynrQzebPAr9EISacmVOXWQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H816 uniprotkb:Q96EB6 intact:EBI-3508943|uniprotkb:Q9H9E5|ensembl:ENSP00000498042 intact:EBI-1802965|uniprotkb:Q2XNF6|uniprotkb:Q5JVQ0|uniprotkb:Q9GZR9|uniprotkb:Q9Y6F0|ensembl:ENSP00000212015 psi-mi:dcr1b_human(display_long)|uniprotkb:DCLRE1B(gene name)|psi-mi:DCLRE1B(display_short)|uniprotkb:SNM1B(gene name synonym)|uniprotkb:DNA cross-link repair 1B protein(gene name synonym)|uniprotkb:SNM1 homolog B(gene name synonym)|uniprotkb:Beta-lactamase DCLRE1B(gene name synonym) psi-mi:sir1_human(display_long)|uniprotkb:NAD-dependent protein deacylase sirtuin-1(gene name synonym)|uniprotkb:SIRT1(gene name)|psi-mi:SIRT1(display_short)|uniprotkb:SIR2L1(gene name synonym)|uniprotkb:SIR2-like protein 1(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478024|imex:IM-26985-315 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0010833"(telomere maintenance via telomere lengthening)|refseq:NP_073747.1|refseq:NP_001306876.1|ensembl:ENSG00000118655(gene)|ensembl:ENST00000650450(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0016604"(nuclear body)|go:"GO:0031627"(telomeric loop formation)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0035312"(5'-3' exodeoxyribonuclease activity)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR011084(DNA repair metallo-beta-lactamase)|interpro:IPR036866|mint:Q9H816|rcsb pdb:3BUA|rcsb pdb:5AHO|rcsb pdb:7A1F|go:"GO:0016233"(telomere capping)|rcsb pdb:7B2X|rcsb pdb:7B9B|reactome:R-HSA-6783310|dip:DIP-42669N refseq:NP_001135970.1|refseq:NP_036370.2|refseq:NP_001300978.1|dip:DIP-29757N|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR026590|interpro:IPR026591|interpro:IPR029035|mint:Q96EB6|rcsb pdb:4I5I|rcsb pdb:4IF6|rcsb pdb:4IG9|rcsb pdb:4KXQ|rcsb pdb:4ZZH|rcsb pdb:4ZZI|rcsb pdb:4ZZJ|rcsb pdb:5BTR|reactome:R-HSA-3371453|reactome:R-HSA-400253|reactome:R-HSA-427359|reactome:R-HSA-9617629|reactome:R-HSA-9707616|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007517"(muscle organ development)|go:"GO:0007569"(cell aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010883"(regulation of lipid storage)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0005739"(mitochondrion)|ensembl:ENSG00000096717(gene)|ensembl:ENST00000212015(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001542"(ovulation from ovarian follicle)|go:"GO:0001650"(fibrillar center)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002039"(p53 binding)|go:"GO:0002821"(positive regulation of adaptive immune response)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0000720"(pyrimidine dimer repair by nucleotide-excision repair)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031393"(negative regulation of prostaglandin biosynthetic process)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031648"(protein destabilization)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032071"(regulation of endodeoxyribonuclease activity)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034391"(regulation of smooth muscle cell apoptotic process)|go:"GO:0034979"(NAD-dependent protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035356"(cellular triglyceride homeostasis)|go:"GO:0035358"(regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042393"(histone binding)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042595"(behavioral response to starvation)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043398"(HLH domain binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0046969"("NAD-dependent histone deacetylase activity (H3-K9 specific)")|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070857"(regulation of bile acid biosynthetic process)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0044321"(response to leptin)|go:"GO:0071441"(negative regulation of histone H3-K14 acetylation)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071900"(regulation of protein serine/threonine kinase activity)|go:"GO:0090335"(regulation of brown fat cell differentiation)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0106230"(protein depropionylation)|go:"GO:0106231"(protein-propionyllysine depropionylase activity)|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901984"(negative regulation of protein acetylation)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904179"(positive regulation of adipose tissue development)|go:"GO:1990254"(keratin filament binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000111"(positive regulation of macrophage apoptotic process)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|go:"GO:2000481"(positive regulation of cAMP-dependent protein kinase activity)|go:"GO:2000619"(negative regulation of histone H4-K16 acetylation)|go:"GO:2000655"(negative regulation of cellular response to testosterone stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor) - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:bl5L/CwIn5xCj46ElzYxmctQgjU9606 rogid:h3zVepuhRhzlINCluVuAn71Btjc9606 rigid:zMIYFynrQzebPAr9EISacmVOXWQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H816 uniprotkb:Q8N5A5 intact:EBI-3508943|uniprotkb:Q9H9E5|ensembl:ENSP00000498042 intact:EBI-3439227|uniprotkb:Q5JWI9|uniprotkb:Q8WUV4|uniprotkb:Q9H401|uniprotkb:Q96JU4|uniprotkb:Q96JI0|uniprotkb:Q8NC55|uniprotkb:Q5JWJ0|uniprotkb:Q4VXN9|uniprotkb:E1P5K1|ensembl:ENSP00000332013 psi-mi:dcr1b_human(display_long)|uniprotkb:DCLRE1B(gene name)|psi-mi:DCLRE1B(display_short)|uniprotkb:SNM1B(gene name synonym)|uniprotkb:DNA cross-link repair 1B protein(gene name synonym)|uniprotkb:SNM1 homolog B(gene name synonym)|uniprotkb:Beta-lactamase DCLRE1B(gene name synonym) psi-mi:zgpat_human(display_long)|uniprotkb:ZGPAT(gene name)|psi-mi:ZGPAT(display_short)|uniprotkb:GPATC6(gene name synonym)|uniprotkb:GPATCH6(gene name synonym)|uniprotkb:KIAA1847(gene name synonym)|uniprotkb:ZC3H9(gene name synonym)|uniprotkb:ZC3HDC9(gene name synonym)|uniprotkb:ZIP(gene name synonym)|uniprotkb:G patch domain-containing protein 6(gene name synonym)|uniprotkb:Zinc finger CCCH domain-containing protein 9(gene name synonym)|uniprotkb:Zinc finger and G patch domain-containing protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478024|imex:IM-26985-315 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0010833"(telomere maintenance via telomere lengthening)|refseq:NP_073747.1|refseq:NP_001306876.1|ensembl:ENSG00000118655(gene)|ensembl:ENST00000650450(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0016604"(nuclear body)|go:"GO:0031627"(telomeric loop formation)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0035312"(5'-3' exodeoxyribonuclease activity)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR011084(DNA repair metallo-beta-lactamase)|interpro:IPR036866|mint:Q9H816|rcsb pdb:3BUA|rcsb pdb:5AHO|rcsb pdb:7A1F|go:"GO:0016233"(telomere capping)|rcsb pdb:7B2X|rcsb pdb:7B9B|reactome:R-HSA-6783310|dip:DIP-42669N refseq:NP_001076582.1|refseq:NP_001182582.1|refseq:NP_001182583.1|refseq:NP_115916.3|refseq:NP_852150.2|ensembl:ENSG00000197114(gene)|ensembl:ENST00000328969(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR000467(D111/G-patch)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR002999(Tudor)|interpro:IPR036855|interpro:IPR041367|interpro:IPR043560|mint:Q8N5A5|rcsb pdb:4II1 - - comment:"author score: 67" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:bl5L/CwIn5xCj46ElzYxmctQgjU9606 rogid:y65Y35/UuhP6dcxRmNZDjEHE4MI9606 rigid:zMIYFynrQzebPAr9EISacmVOXWQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H816 uniprotkb:Q9NYB0 intact:EBI-3508943|uniprotkb:Q9H9E5|ensembl:ENSP00000498042 intact:EBI-750109|uniprotkb:B4DQN4|uniprotkb:Q4W4Y2|uniprotkb:Q8WYZ3|uniprotkb:Q9NWR2|ensembl:ENSP00000300086 psi-mi:dcr1b_human(display_long)|uniprotkb:DCLRE1B(gene name)|psi-mi:DCLRE1B(display_short)|uniprotkb:SNM1B(gene name synonym)|uniprotkb:DNA cross-link repair 1B protein(gene name synonym)|uniprotkb:SNM1 homolog B(gene name synonym)|uniprotkb:Beta-lactamase DCLRE1B(gene name synonym) psi-mi:te2ip_human(display_long)|uniprotkb:DRIP5(gene name synonym)|uniprotkb:TERF2IP(gene name)|psi-mi:TERF2IP(display_short)|uniprotkb:RAP1(gene name synonym)|uniprotkb:PP8000(orf name)|uniprotkb:Dopamine receptor-interacting protein 5(gene name synonym)|uniprotkb:Repressor/activator protein 1 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478024|imex:IM-26985-315 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0010833"(telomere maintenance via telomere lengthening)|refseq:NP_073747.1|refseq:NP_001306876.1|ensembl:ENSG00000118655(gene)|ensembl:ENST00000650450(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0016604"(nuclear body)|go:"GO:0031627"(telomeric loop formation)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0035312"(5'-3' exodeoxyribonuclease activity)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR011084(DNA repair metallo-beta-lactamase)|interpro:IPR036866|mint:Q9H816|rcsb pdb:3BUA|rcsb pdb:5AHO|rcsb pdb:7A1F|go:"GO:0016233"(telomere capping)|rcsb pdb:7B2X|rcsb pdb:7B9B|reactome:R-HSA-6783310|dip:DIP-42669N ensembl:ENST00000300086(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|ensembl:ENSG00000166848(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016604"(nuclear body)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|refseq:NP_061848.2|dip:DIP-34868N|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032205"(negative regulation of telomere maintenance)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0048239"(negative regulation of DNA recombination at telomere)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|interpro:IPR001357(BRCT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015010(Rap1 Myb)|interpro:IPR021661|interpro:IPR036420|interpro:IPR038104|interpro:IPR039595|mint:Q9NYB0|rcsb pdb:1FEX|rcsb pdb:3K6G|rcsb pdb:4RQI|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095 - - comment:"author score: 118" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:bl5L/CwIn5xCj46ElzYxmctQgjU9606 rogid:rH6GKcTfjxpXw0MAcOHQk29nz+09606 rigid:zMIYFynrQzebPAr9EISacmVOXWQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H816 uniprotkb:Q15554 intact:EBI-3508943|uniprotkb:Q9H9E5|ensembl:ENSP00000498042 intact:EBI-706637|ensembl:ENSP00000254942|intact:EBI-706651 psi-mi:dcr1b_human(display_long)|uniprotkb:DCLRE1B(gene name)|psi-mi:DCLRE1B(display_short)|uniprotkb:SNM1B(gene name synonym)|uniprotkb:DNA cross-link repair 1B protein(gene name synonym)|uniprotkb:SNM1 homolog B(gene name synonym)|uniprotkb:Beta-lactamase DCLRE1B(gene name synonym) psi-mi:terf2_human(display_long)|uniprotkb:TTAGGG repeat-binding factor 2(gene name synonym)|uniprotkb:Telomeric DNA-binding protein(gene name synonym)|uniprotkb:TERF2(gene name)|psi-mi:TERF2(display_short)|uniprotkb:TRF2(gene name synonym)|uniprotkb:TRBF2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478024|imex:IM-26985-315 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0010833"(telomere maintenance via telomere lengthening)|refseq:NP_073747.1|refseq:NP_001306876.1|ensembl:ENSG00000118655(gene)|ensembl:ENST00000650450(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0016604"(nuclear body)|go:"GO:0031627"(telomeric loop formation)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0035312"(5'-3' exodeoxyribonuclease activity)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR011084(DNA repair metallo-beta-lactamase)|interpro:IPR036866|mint:Q9H816|rcsb pdb:3BUA|rcsb pdb:5AHO|rcsb pdb:7A1F|go:"GO:0016233"(telomere capping)|rcsb pdb:7B2X|rcsb pdb:7B9B|reactome:R-HSA-6783310|dip:DIP-42669N go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032208"(negative regulation of telomere maintenance via recombination)|go:"GO:0032210"(regulation of telomere maintenance via telomerase)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032214"(negative regulation of telomere maintenance via semi-conservative replication)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0061820"(telomeric D-loop disassembly)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0090398"(cellular senescence)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:0099087"(anterograde axonal transport of messenger ribonucleoprotein complex)|go:"GO:1903770"(negative regulation of beta-galactosidase activity)|go:"GO:1903824"(negative regulation of telomere single strand break repair)|go:"GO:1904115"(axon cytoplasm)|go:"GO:0032205"(negative regulation of telomere maintenance)|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095|ensembl:ENSG00000132604(gene)|ensembl:ENST00000254942(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006278"(RNA-dependent DNA biosynthetic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016233"(telomere capping)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0031627"(telomeric loop formation)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904430"(negative regulation of t-circle formation)|go:"GO:1905778"(negative regulation of exonuclease activity)|go:"GO:1905839"(negative regulation of telomeric D-loop disassembly)|go:"GO:2000773"(negative regulation of cellular senescence)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013867(Telomere repeat binding factor, dimerisation)|interpro:IPR017357(Telomeric repeat-binding factor 1, Pin2)|interpro:IPR017930|interpro:IPR030657|interpro:IPR031902|interpro:IPR036507|mint:Q15554|rcsb pdb:1H6P|rcsb pdb:1VF9|rcsb pdb:1VFC|rcsb pdb:1W0U|rcsb pdb:1XG1|rcsb pdb:3BU8|rcsb pdb:3BUA|rcsb pdb:3K6G|rcsb pdb:3SJM|rcsb pdb:4M7C|rcsb pdb:4RQI|rcsb pdb:5WQD|rcsb pdb:5XYF|rcsb pdb:6J67|rcsb pdb:7C5D|reactome:R-HSA-110328|reactome:R-HSA-110329|go:"GO:1904354"(negative regulation of telomere capping)|refseq:NP_005643.2|dip:DIP-34052N - - comment:"author score: 126" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:bl5L/CwIn5xCj46ElzYxmctQgjU9606 rogid:MzPf3uCpzJzkIKvgaP0Xro7xnHo9606 rigid:zMIYFynrQzebPAr9EISacmVOXWQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UER7 uniprotkb:Q13367 intact:EBI-77321|ensembl:ENSP00000266000|ensembl:ENSP00000363668|ensembl:ENSP00000372539|ensembl:ENSP00000372681|ensembl:ENSP00000382014|ensembl:ENSP00000382281|ensembl:ENSP00000394108|ensembl:ENSP00000404376|ensembl:ENSP00000404623|ensembl:ENSP00000410772|uniprotkb:O14747|uniprotkb:O15141|uniprotkb:O15208|uniprotkb:Q9BWI3|uniprotkb:B4E1I3|uniprotkb:F5H082|uniprotkb:Q5STK9|uniprotkb:F5ANJ6|uniprotkb:F5ANJ7 intact:EBI-1642811|uniprotkb:O14808|uniprotkb:Q52LY8|uniprotkb:A4Z4T7|uniprotkb:B7ZKR7|uniprotkb:B7ZKS0|intact:EBI-28985906|ensembl:ENSP00000499235 psi-mi:daxx_human(display_long)|uniprotkb:DAXX(gene name)|psi-mi:DAXX(display_short)|uniprotkb:BING2(gene name synonym)|uniprotkb:DAP6(gene name synonym)|uniprotkb:Daxx(gene name synonym)|uniprotkb:Fas death domain-associated protein(gene name synonym)|uniprotkb:ETS1-associated protein 1(gene name synonym) psi-mi:ap3b2_human(display_long)|uniprotkb:AP3B2(gene name)|psi-mi:AP3B2(display_short)|uniprotkb:Adaptor protein complex AP-3 subunit beta-2(gene name synonym)|uniprotkb:Beta-3B-adaptin(gene name synonym)|uniprotkb:Clathrin assembly protein complex 3 beta-2 large chain(gene name synonym)|uniprotkb:Neuron-specific vesicle coat protein beta-NAP(gene name synonym)|uniprotkb:Adaptor-related protein complex 3 subunit beta-2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477958|imex:IM-26985-313 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000206206(gene)|ensembl:ENSG00000206279(gene)|ensembl:ENSG00000227046(gene)|ensembl:ENSG00000231617(gene)|ensembl:ENSG00000204209(gene)|ensembl:ENST00000266000(transcript)|ensembl:ENST00000374542(transcript)|ensembl:ENST00000383062(transcript)|ensembl:ENST00000383194(transcript)|ensembl:ENST00000399060(transcript)|ensembl:ENST00000399344(transcript)|ensembl:ENST00000433482(transcript)|ensembl:ENST00000436311(transcript)|ensembl:ENST00000445009(transcript)|ensembl:ENST00000455860(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0072738"(cellular response to diamide)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903936"(cellular response to sodium arsenite)|interpro:IPR005012(Daxx protein)|interpro:IPR031333|interpro:IPR038298|mint:Q9UER7|rcsb pdb:2KQS|rcsb pdb:2KZS|rcsb pdb:2KZU|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:5GRQ|rcsb pdb:5KDM|rcsb pdb:5Y18|rcsb pdb:5Y6O|reactome:R-HSA-3899300|reactome:R-HSA-6804757|reactome:R-HSA-9609690|reactome:R-HSA-9670095|reactome:R-HSA-9670613|reactome:R-HSA-9670615|refseq:NP_001135441.1|refseq:NP_001341.1|refseq:NP_001241646.1|dip:DIP-27628N refseq:NP_001265440.1|refseq:NP_001265441.1|refseq:NP_004635.2|refseq:NP_001335370.1|ensembl:ENST00000535348|ensembl:ENSP00000438721|ensembl:ENST00000535359|ensembl:ENSP00000440984|ensembl:ENSP00000499235|ensembl:ENSG00000103723(gene)|ensembl:ENST00000668990(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0030123"(AP-3 adaptor complex)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0048490"(anterograde synaptic vesicle transport)|go:"GO:0097708"(intracellular vesicle)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR026739|interpro:IPR026740|interpro:IPR029390|mint:Q13367 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lM3F/1ay7qvt8NkGWvgfSvBX1qQ9606 rogid:UpuB/FVFDHPUjAf40y3SxOL9xzA9606 rigid:VSxBgtiJWZil2fZ4Nb8xWrheH7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UER7 uniprotkb:Q93009 intact:EBI-77321|ensembl:ENSP00000266000|ensembl:ENSP00000363668|ensembl:ENSP00000372539|ensembl:ENSP00000372681|ensembl:ENSP00000382014|ensembl:ENSP00000382281|ensembl:ENSP00000394108|ensembl:ENSP00000404376|ensembl:ENSP00000404623|ensembl:ENSP00000410772|uniprotkb:O14747|uniprotkb:O15141|uniprotkb:O15208|uniprotkb:Q9BWI3|uniprotkb:B4E1I3|uniprotkb:F5H082|uniprotkb:Q5STK9|uniprotkb:F5ANJ6|uniprotkb:F5ANJ7 intact:EBI-302474|uniprotkb:A6NMY8|intact:EBI-28988230|ensembl:ENSP00000343535|uniprotkb:B7Z815|uniprotkb:H0Y3G8 psi-mi:daxx_human(display_long)|uniprotkb:DAXX(gene name)|psi-mi:DAXX(display_short)|uniprotkb:BING2(gene name synonym)|uniprotkb:DAP6(gene name synonym)|uniprotkb:Daxx(gene name synonym)|uniprotkb:Fas death domain-associated protein(gene name synonym)|uniprotkb:ETS1-associated protein 1(gene name synonym) psi-mi:ubp7_human(display_long)|uniprotkb:USP7(gene name)|psi-mi:USP7(display_short)|uniprotkb:HAUSP(gene name synonym)|uniprotkb:Ubiquitin thioesterase 7(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 7(gene name synonym)|uniprotkb:Deubiquitinating enzyme 7(gene name synonym)|uniprotkb:Herpesvirus-associated ubiquitin-specific protease(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477958|imex:IM-26985-313 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000206206(gene)|ensembl:ENSG00000206279(gene)|ensembl:ENSG00000227046(gene)|ensembl:ENSG00000231617(gene)|ensembl:ENSG00000204209(gene)|ensembl:ENST00000266000(transcript)|ensembl:ENST00000374542(transcript)|ensembl:ENST00000383062(transcript)|ensembl:ENST00000383194(transcript)|ensembl:ENST00000399060(transcript)|ensembl:ENST00000399344(transcript)|ensembl:ENST00000433482(transcript)|ensembl:ENST00000436311(transcript)|ensembl:ENST00000445009(transcript)|ensembl:ENST00000455860(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0072738"(cellular response to diamide)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903936"(cellular response to sodium arsenite)|interpro:IPR005012(Daxx protein)|interpro:IPR031333|interpro:IPR038298|mint:Q9UER7|rcsb pdb:2KQS|rcsb pdb:2KZS|rcsb pdb:2KZU|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:5GRQ|rcsb pdb:5KDM|rcsb pdb:5Y18|rcsb pdb:5Y6O|reactome:R-HSA-3899300|reactome:R-HSA-6804757|reactome:R-HSA-9609690|reactome:R-HSA-9670095|reactome:R-HSA-9670613|reactome:R-HSA-9670615|refseq:NP_001135441.1|refseq:NP_001341.1|refseq:NP_001241646.1|dip:DIP-27628N rcsb pdb:4PYZ|rcsb pdb:4WPH|rcsb pdb:4WPI|rcsb pdb:4YOC|rcsb pdb:4YSI|rcsb pdb:4Z96|rcsb pdb:4Z97|rcsb pdb:5C56|rcsb pdb:5C6D|rcsb pdb:5FWI|rcsb pdb:5GG4|rcsb pdb:5J7T|rcsb pdb:5JTJ|rcsb pdb:5JTV|rcsb pdb:5KYB|rcsb pdb:4M5X|rcsb pdb:5KYC|rcsb pdb:5KYD|rcsb pdb:5KYE|rcsb pdb:5KYF|interpro:IPR029346|interpro:IPR038765|mint:Q93009|rcsb pdb:1NB8|rcsb pdb:1NBF|rcsb pdb:1YY6|rcsb pdb:1YZE|rcsb pdb:2F1W|rcsb pdb:2F1X|rcsb pdb:2F1Y|rcsb pdb:2F1Z|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2FOP|rcsb pdb:2KVR|rcsb pdb:2XXN|rcsb pdb:2YLM|rcsb pdb:3MQR|rcsb pdb:3MQS|rcsb pdb:4JJQ|rcsb pdb:4KG9|rcsb pdb:4M5W|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010216"(maintenance of DNA methylation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050821"(protein stabilization)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0101005"(deubiquitinase activity)|go:"GO:1901537"(positive regulation of DNA demethylation)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1904353"(regulation of telomere capping)|go:"GO:1905279"(regulation of retrograde transport, endosome to Golgi)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR002083(MATH)|interpro:IPR008974(TRAF-like)|interpro:IPR018200|interpro:IPR024729|interpro:IPR028889|ensembl:ENSG00000187555(gene)|ensembl:ENST00000344836(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006111"(regulation of gluconeogenesis)|rcsb pdb:5N9R|rcsb pdb:5N9T|rcsb pdb:5NGE|rcsb pdb:5NGF|rcsb pdb:5UQV|rcsb pdb:5UQX|rcsb pdb:5VS6|rcsb pdb:5VSB|rcsb pdb:5VSK|rcsb pdb:5WHC|rcsb pdb:6F5H|rcsb pdb:6M1K|rcsb pdb:6P5L|rcsb pdb:6VN2|rcsb pdb:6VN3|rcsb pdb:6VN4|rcsb pdb:6VN5|rcsb pdb:6VN6|rcsb pdb:7CM2|reactome:R-HSA-5689880|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804757|reactome:R-HSA-8866652|reactome:R-HSA-8948747|refseq:NP_001273386.1|refseq:NP_003461.2|refseq:NP_001308787.1|ensembl:ENSP00000343535|ensembl:ENST00000381886|ensembl:ENSP00000371310|dip:DIP-29053N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lM3F/1ay7qvt8NkGWvgfSvBX1qQ9606 rogid:V+PXXBRM2zwlGQaeFiyjaQ9yf+A9606 rigid:VSxBgtiJWZil2fZ4Nb8xWrheH7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UER7 uniprotkb:Q16576 intact:EBI-77321|ensembl:ENSP00000266000|ensembl:ENSP00000363668|ensembl:ENSP00000372539|ensembl:ENSP00000372681|ensembl:ENSP00000382014|ensembl:ENSP00000382281|ensembl:ENSP00000394108|ensembl:ENSP00000404376|ensembl:ENSP00000404623|ensembl:ENSP00000410772|uniprotkb:O14747|uniprotkb:O15141|uniprotkb:O15208|uniprotkb:Q9BWI3|uniprotkb:B4E1I3|uniprotkb:F5H082|uniprotkb:Q5STK9|uniprotkb:F5ANJ6|uniprotkb:F5ANJ7 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 psi-mi:daxx_human(display_long)|uniprotkb:DAXX(gene name)|psi-mi:DAXX(display_short)|uniprotkb:BING2(gene name synonym)|uniprotkb:DAP6(gene name synonym)|uniprotkb:Daxx(gene name synonym)|uniprotkb:Fas death domain-associated protein(gene name synonym)|uniprotkb:ETS1-associated protein 1(gene name synonym) psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477958|imex:IM-26985-313 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000206206(gene)|ensembl:ENSG00000206279(gene)|ensembl:ENSG00000227046(gene)|ensembl:ENSG00000231617(gene)|ensembl:ENSG00000204209(gene)|ensembl:ENST00000266000(transcript)|ensembl:ENST00000374542(transcript)|ensembl:ENST00000383062(transcript)|ensembl:ENST00000383194(transcript)|ensembl:ENST00000399060(transcript)|ensembl:ENST00000399344(transcript)|ensembl:ENST00000433482(transcript)|ensembl:ENST00000436311(transcript)|ensembl:ENST00000445009(transcript)|ensembl:ENST00000455860(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0072738"(cellular response to diamide)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903936"(cellular response to sodium arsenite)|interpro:IPR005012(Daxx protein)|interpro:IPR031333|interpro:IPR038298|mint:Q9UER7|rcsb pdb:2KQS|rcsb pdb:2KZS|rcsb pdb:2KZU|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:5GRQ|rcsb pdb:5KDM|rcsb pdb:5Y18|rcsb pdb:5Y6O|reactome:R-HSA-3899300|reactome:R-HSA-6804757|reactome:R-HSA-9609690|reactome:R-HSA-9670095|reactome:R-HSA-9670613|reactome:R-HSA-9670615|refseq:NP_001135441.1|refseq:NP_001341.1|refseq:NP_001241646.1|dip:DIP-27628N refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lM3F/1ay7qvt8NkGWvgfSvBX1qQ9606 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rigid:VSxBgtiJWZil2fZ4Nb8xWrheH7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UER7 uniprotkb:Q8NE71 intact:EBI-77321|ensembl:ENSP00000266000|ensembl:ENSP00000363668|ensembl:ENSP00000372539|ensembl:ENSP00000372681|ensembl:ENSP00000382014|ensembl:ENSP00000382281|ensembl:ENSP00000394108|ensembl:ENSP00000404376|ensembl:ENSP00000404623|ensembl:ENSP00000410772|uniprotkb:O14747|uniprotkb:O15141|uniprotkb:O15208|uniprotkb:Q9BWI3|uniprotkb:B4E1I3|uniprotkb:F5H082|uniprotkb:Q5STK9|uniprotkb:F5ANJ6|uniprotkb:F5ANJ7 intact:EBI-720571|uniprotkb:A2BF75|uniprotkb:O14897|uniprotkb:Q69YP6|ensembl:ENSP00000313603|ensembl:ENSP00000373082|ensembl:ENSP00000389065|ensembl:ENSP00000411327|ensembl:ENSP00000412553|ensembl:ENSP00000413319|ensembl:ENSP00000414373 psi-mi:daxx_human(display_long)|uniprotkb:DAXX(gene name)|psi-mi:DAXX(display_short)|uniprotkb:BING2(gene name synonym)|uniprotkb:DAP6(gene name synonym)|uniprotkb:Daxx(gene name synonym)|uniprotkb:Fas death domain-associated protein(gene name synonym)|uniprotkb:ETS1-associated protein 1(gene name synonym) psi-mi:abcf1_human(display_long)|uniprotkb:ATP-binding cassette 50(gene name synonym)|uniprotkb:TNF-alpha-stimulated ABC protein(gene name synonym)|uniprotkb:ABCF1(gene name)|psi-mi:ABCF1(display_short)|uniprotkb:ABC50(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477958|imex:IM-26985-313 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000206206(gene)|ensembl:ENSG00000206279(gene)|ensembl:ENSG00000227046(gene)|ensembl:ENSG00000231617(gene)|ensembl:ENSG00000204209(gene)|ensembl:ENST00000266000(transcript)|ensembl:ENST00000374542(transcript)|ensembl:ENST00000383062(transcript)|ensembl:ENST00000383194(transcript)|ensembl:ENST00000399060(transcript)|ensembl:ENST00000399344(transcript)|ensembl:ENST00000433482(transcript)|ensembl:ENST00000436311(transcript)|ensembl:ENST00000445009(transcript)|ensembl:ENST00000455860(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0072738"(cellular response to diamide)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903936"(cellular response to sodium arsenite)|interpro:IPR005012(Daxx protein)|interpro:IPR031333|interpro:IPR038298|mint:Q9UER7|rcsb pdb:2KQS|rcsb pdb:2KZS|rcsb pdb:2KZU|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:5GRQ|rcsb pdb:5KDM|rcsb pdb:5Y18|rcsb pdb:5Y6O|reactome:R-HSA-3899300|reactome:R-HSA-6804757|reactome:R-HSA-9609690|reactome:R-HSA-9670095|reactome:R-HSA-9670613|reactome:R-HSA-9670615|refseq:NP_001135441.1|refseq:NP_001341.1|refseq:NP_001241646.1|dip:DIP-27628N refseq:NP_001020262.1|refseq:NP_001081.1|dip:DIP-50666N|ensembl:ENSG00000204574(gene)|ensembl:ENSG00000206490(gene)|ensembl:ENSG00000225989(gene)|ensembl:ENSG00000231129(gene)|ensembl:ENSG00000232169(gene)|ensembl:ENSG00000236149(gene)|ensembl:ENSG00000236342(gene)|ensembl:ENST00000326195(transcript)|ensembl:ENST00000383588(transcript)|ensembl:ENST00000419893(transcript)|ensembl:ENST00000423247(transcript)|ensembl:ENST00000426219(transcript)|ensembl:ENST00000457078(transcript)|ensembl:ENST00000457111(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006954"(inflammatory response)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0008494"(translation activator activity)|go:"GO:0016020"(membrane)|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR003439(ABC transporter-like)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR017871|interpro:IPR027417|mint:Q8NE71|rcsb pdb:5ZXD|reactome:R-HSA-382556 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lM3F/1ay7qvt8NkGWvgfSvBX1qQ9606 rogid:DdEbnAZo4bv75DRSzSmcdNo6QsM9606 rigid:VSxBgtiJWZil2fZ4Nb8xWrheH7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UER7 uniprotkb:Q96T58 intact:EBI-77321|ensembl:ENSP00000266000|ensembl:ENSP00000363668|ensembl:ENSP00000372539|ensembl:ENSP00000372681|ensembl:ENSP00000382014|ensembl:ENSP00000382281|ensembl:ENSP00000394108|ensembl:ENSP00000404376|ensembl:ENSP00000404623|ensembl:ENSP00000410772|uniprotkb:O14747|uniprotkb:O15141|uniprotkb:O15208|uniprotkb:Q9BWI3|uniprotkb:B4E1I3|uniprotkb:F5H082|uniprotkb:Q5STK9|uniprotkb:F5ANJ6|uniprotkb:F5ANJ7 intact:EBI-765739|uniprotkb:Q9UQ01|uniprotkb:Q9Y556|uniprotkb:Q9H9A8|uniprotkb:Q9NWH5|intact:EBI-28975565|ensembl:ENSP00000364912 psi-mi:daxx_human(display_long)|uniprotkb:DAXX(gene name)|psi-mi:DAXX(display_short)|uniprotkb:BING2(gene name synonym)|uniprotkb:DAP6(gene name synonym)|uniprotkb:Daxx(gene name synonym)|uniprotkb:Fas death domain-associated protein(gene name synonym)|uniprotkb:ETS1-associated protein 1(gene name synonym) psi-mi:mint_human(display_long)|uniprotkb:SPEN homolog(gene name synonym)|uniprotkb:SMART/HDAC1-associated repressor protein(gene name synonym)|uniprotkb:KIAA0929(gene name synonym)|uniprotkb:MINT(gene name synonym)|uniprotkb:SHARP(gene name synonym)|uniprotkb:SPEN(gene name)|psi-mi:SPEN(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477958|imex:IM-26985-313 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000206206(gene)|ensembl:ENSG00000206279(gene)|ensembl:ENSG00000227046(gene)|ensembl:ENSG00000231617(gene)|ensembl:ENSG00000204209(gene)|ensembl:ENST00000266000(transcript)|ensembl:ENST00000374542(transcript)|ensembl:ENST00000383062(transcript)|ensembl:ENST00000383194(transcript)|ensembl:ENST00000399060(transcript)|ensembl:ENST00000399344(transcript)|ensembl:ENST00000433482(transcript)|ensembl:ENST00000436311(transcript)|ensembl:ENST00000445009(transcript)|ensembl:ENST00000455860(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0072738"(cellular response to diamide)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903936"(cellular response to sodium arsenite)|interpro:IPR005012(Daxx protein)|interpro:IPR031333|interpro:IPR038298|mint:Q9UER7|rcsb pdb:2KQS|rcsb pdb:2KZS|rcsb pdb:2KZU|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:5GRQ|rcsb pdb:5KDM|rcsb pdb:5Y18|rcsb pdb:5Y6O|reactome:R-HSA-3899300|reactome:R-HSA-6804757|reactome:R-HSA-9609690|reactome:R-HSA-9670095|reactome:R-HSA-9670613|reactome:R-HSA-9670615|refseq:NP_001135441.1|refseq:NP_001341.1|refseq:NP_001241646.1|dip:DIP-27628N refseq:NP_055816.2|ensembl:ENSP00000364912|dip:DIP-34569N|ensembl:ENSG00000065526(gene)|ensembl:ENST00000375759(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR010912(Spen paralogue and orthologue C-terminal, metazoa)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012921(Spen paralogue and orthologue C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR034172|interpro:IPR034173|interpro:IPR034174|interpro:IPR034175|interpro:IPR035979|mint:Q96T58|rcsb pdb:1OW1|rcsb pdb:2RT5|rcsb pdb:4P6Q|reactome:R-HSA-9013422|go:"GO:0005654"(nucleoplasm)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0045892"(negative regulation of transcription, DNA-templated) - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lM3F/1ay7qvt8NkGWvgfSvBX1qQ9606 rogid:m7bdkKVATaG4dkFG/BYXRn4jOIk9606 rigid:VSxBgtiJWZil2fZ4Nb8xWrheH7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UER7 uniprotkb:P25440 intact:EBI-77321|ensembl:ENSP00000266000|ensembl:ENSP00000363668|ensembl:ENSP00000372539|ensembl:ENSP00000372681|ensembl:ENSP00000382014|ensembl:ENSP00000382281|ensembl:ENSP00000394108|ensembl:ENSP00000404376|ensembl:ENSP00000404623|ensembl:ENSP00000410772|uniprotkb:O14747|uniprotkb:O15141|uniprotkb:O15208|uniprotkb:Q9BWI3|uniprotkb:B4E1I3|uniprotkb:F5H082|uniprotkb:Q5STK9|uniprotkb:F5ANJ6|uniprotkb:F5ANJ7 intact:EBI-2874802|uniprotkb:Q5STC9|uniprotkb:Q6P3U2|uniprotkb:O00699|uniprotkb:B1AZT1|uniprotkb:B0S7P0|uniprotkb:Q969U4|uniprotkb:Q15310|uniprotkb:O00700|uniprotkb:A2AAU0|uniprotkb:Q63HQ9|uniprotkb:Q658Y7|ensembl:ENSP00000363958|ensembl:ENSP00000363964|ensembl:ENSP00000372588|ensembl:ENSP00000382444|ensembl:ENSP00000382445|ensembl:ENSP00000391246|ensembl:ENSP00000399009|ensembl:ENSP00000401791|ensembl:ENSP00000409145|ensembl:ENSP00000449380|ensembl:ENSP00000449609|ensembl:ENSP00000502900 psi-mi:daxx_human(display_long)|uniprotkb:DAXX(gene name)|psi-mi:DAXX(display_short)|uniprotkb:BING2(gene name synonym)|uniprotkb:DAP6(gene name synonym)|uniprotkb:Daxx(gene name synonym)|uniprotkb:Fas death domain-associated protein(gene name synonym)|uniprotkb:ETS1-associated protein 1(gene name synonym) psi-mi:brd2_human(display_long)|uniprotkb:BRD2(gene name)|psi-mi:BRD2(display_short)|uniprotkb:KIAA9001(gene name synonym)|uniprotkb:RING3(gene name synonym)|uniprotkb:O27.1.1(gene name synonym)|uniprotkb:Really interesting new gene 3 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477958|imex:IM-26985-313 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000206206(gene)|ensembl:ENSG00000206279(gene)|ensembl:ENSG00000227046(gene)|ensembl:ENSG00000231617(gene)|ensembl:ENSG00000204209(gene)|ensembl:ENST00000266000(transcript)|ensembl:ENST00000374542(transcript)|ensembl:ENST00000383062(transcript)|ensembl:ENST00000383194(transcript)|ensembl:ENST00000399060(transcript)|ensembl:ENST00000399344(transcript)|ensembl:ENST00000433482(transcript)|ensembl:ENST00000436311(transcript)|ensembl:ENST00000445009(transcript)|ensembl:ENST00000455860(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0072738"(cellular response to diamide)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903936"(cellular response to sodium arsenite)|interpro:IPR005012(Daxx protein)|interpro:IPR031333|interpro:IPR038298|mint:Q9UER7|rcsb pdb:2KQS|rcsb pdb:2KZS|rcsb pdb:2KZU|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:5GRQ|rcsb pdb:5KDM|rcsb pdb:5Y18|rcsb pdb:5Y6O|reactome:R-HSA-3899300|reactome:R-HSA-6804757|reactome:R-HSA-9609690|reactome:R-HSA-9670095|reactome:R-HSA-9670613|reactome:R-HSA-9670615|refseq:NP_001135441.1|refseq:NP_001341.1|refseq:NP_001241646.1|dip:DIP-27628N refseq:NP_001278915.1|refseq:NP_001106653.1|refseq:NP_001186384.1|refseq:NP_001186385.1|refseq:NP_005095.1|dip:DIP-60835N|ensembl:ENSG00000204256(gene)|ensembl:ENSG00000215077(gene)|ensembl:ENSG00000234507(gene)|ensembl:ENSG00000234704(gene)|ensembl:ENSG00000235307(gene)|ensembl:ENST00000374825(transcript)|ensembl:ENST00000374831(transcript)|ensembl:ENST00000383108(transcript)|ensembl:ENST00000399528(transcript)|ensembl:ENST00000399529(transcript)|ensembl:ENST00000414731(transcript)|ensembl:ENST00000438194(transcript)|ensembl:ENST00000449085(transcript)|ensembl:ENST00000449118(transcript)|ensembl:ENST00000549126(transcript)|ensembl:ENST00000552587(transcript)|ensembl:ENST00000678250(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016607"(nuclear speck)|go:"GO:0070577"(lysine-acetylated histone binding)|interpro:IPR001487(Bromodomain)|interpro:IPR018359|interpro:IPR027353|interpro:IPR036427|interpro:IPR038336|interpro:IPR043508|interpro:IPR043509|mint:P25440|rcsb pdb:1X0J|rcsb pdb:2DVQ|rcsb pdb:2DVR|rcsb pdb:2DVS|rcsb pdb:2DVV|rcsb pdb:2E3K|rcsb pdb:2G4A|rcsb pdb:2YDW|rcsb pdb:2YEK|rcsb pdb:3AQA|rcsb pdb:3ONI|rcsb pdb:4A9E|rcsb pdb:4A9F|rcsb pdb:4A9H|rcsb pdb:4A9I|rcsb pdb:4A9J|rcsb pdb:4A9M|rcsb pdb:4A9N|rcsb pdb:4A9O|rcsb pdb:4AKN|rcsb pdb:4ALG|rcsb pdb:4ALH|rcsb pdb:4J1P|rcsb pdb:4MR5|rcsb pdb:4QEU|rcsb pdb:4QEV|rcsb pdb:4QEW|rcsb pdb:4UYF|rcsb pdb:4UYG|rcsb pdb:4UYH|rcsb pdb:5BT5|rcsb pdb:5DFB|rcsb pdb:5DFC|rcsb pdb:5DFD|rcsb pdb:5DW1|rcsb pdb:5EK9|rcsb pdb:5HEL|rcsb pdb:5HEM|rcsb pdb:5HEN|rcsb pdb:5HFQ|rcsb pdb:5IBN|rcsb pdb:5IG6|rcsb pdb:5N2L|rcsb pdb:5O38|rcsb pdb:5O39|rcsb pdb:5O3A|rcsb pdb:5O3B|rcsb pdb:5O3C|rcsb pdb:5O3D|rcsb pdb:5O3E|rcsb pdb:5O3F|rcsb pdb:5O3G|rcsb pdb:5O3H|rcsb pdb:5O3I|rcsb pdb:5U5S|rcsb pdb:5U6V|rcsb pdb:5UEW|rcsb pdb:5XHE|rcsb pdb:5XHK|rcsb pdb:6CUI|rcsb pdb:6DB0|rcsb pdb:6DBC|rcsb pdb:6DDI|rcsb pdb:6DDJ|rcsb pdb:4MR6|rcsb pdb:6E6J|rcsb pdb:6FFE|rcsb pdb:6FFF|rcsb pdb:6FFG|rcsb pdb:6I80|rcsb pdb:6I81|rcsb pdb:6JKE|rcsb pdb:6K05|rcsb pdb:6MO7|rcsb pdb:6MO8|rcsb pdb:6MO9|rcsb pdb:6MOA|rcsb pdb:6ONY|rcsb pdb:6SWO|rcsb pdb:6SWP|rcsb pdb:6TQ1|rcsb pdb:6TQ2|rcsb pdb:6U61|rcsb pdb:6U71|rcsb pdb:6U8H|rcsb pdb:6ULQ|rcsb pdb:6ULT|rcsb pdb:6VIY|rcsb pdb:6YTM|rcsb pdb:6Z7F|rcsb pdb:6Z8P|rcsb pdb:6ZB0|rcsb pdb:6ZB1|rcsb pdb:6ZB2|rcsb pdb:7JX7|rcsb pdb:7L6D|rcsb pdb:7NQ5|rcsb pdb:7NQ7|rcsb pdb:7NQ8|rcsb pdb:7NQ9|rcsb pdb:7NQI|rcsb pdb:7NQJ|reactome:R-HSA-8951936|rcsb pdb:6K04 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lM3F/1ay7qvt8NkGWvgfSvBX1qQ9606 rogid:Q3ELpiTZgboufxPDV/bypJZC2oY9606 rigid:VSxBgtiJWZil2fZ4Nb8xWrheH7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UER7 uniprotkb:Q7Z4V5 intact:EBI-77321|ensembl:ENSP00000266000|ensembl:ENSP00000363668|ensembl:ENSP00000372539|ensembl:ENSP00000372681|ensembl:ENSP00000382014|ensembl:ENSP00000382281|ensembl:ENSP00000394108|ensembl:ENSP00000404376|ensembl:ENSP00000404623|ensembl:ENSP00000410772|uniprotkb:O14747|uniprotkb:O15141|uniprotkb:O15208|uniprotkb:Q9BWI3|uniprotkb:B4E1I3|uniprotkb:F5H082|uniprotkb:Q5STK9|uniprotkb:F5ANJ6|uniprotkb:F5ANJ7 intact:EBI-1049136|uniprotkb:Q96GI5|uniprotkb:Q9BW08|uniprotkb:K7EQZ6|uniprotkb:I3L080|ensembl:ENSP00000483345 psi-mi:daxx_human(display_long)|uniprotkb:DAXX(gene name)|psi-mi:DAXX(display_short)|uniprotkb:BING2(gene name synonym)|uniprotkb:DAP6(gene name synonym)|uniprotkb:Daxx(gene name synonym)|uniprotkb:Fas death domain-associated protein(gene name synonym)|uniprotkb:ETS1-associated protein 1(gene name synonym) psi-mi:hdgr2_human(display_long)|uniprotkb:HRP2(gene name synonym)|uniprotkb:HDGFL2(gene name)|psi-mi:HDGFL2(display_short)|uniprotkb:HDGF2(gene name synonym)|uniprotkb:HDGFRP2(gene name synonym)|uniprotkb:Hepatoma-derived growth factor 2(gene name synonym)|uniprotkb:UNQ785/PRO1604(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477958|imex:IM-26985-313 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000206206(gene)|ensembl:ENSG00000206279(gene)|ensembl:ENSG00000227046(gene)|ensembl:ENSG00000231617(gene)|ensembl:ENSG00000204209(gene)|ensembl:ENST00000266000(transcript)|ensembl:ENST00000374542(transcript)|ensembl:ENST00000383062(transcript)|ensembl:ENST00000383194(transcript)|ensembl:ENST00000399060(transcript)|ensembl:ENST00000399344(transcript)|ensembl:ENST00000433482(transcript)|ensembl:ENST00000436311(transcript)|ensembl:ENST00000445009(transcript)|ensembl:ENST00000455860(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0072738"(cellular response to diamide)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903936"(cellular response to sodium arsenite)|interpro:IPR005012(Daxx protein)|interpro:IPR031333|interpro:IPR038298|mint:Q9UER7|rcsb pdb:2KQS|rcsb pdb:2KZS|rcsb pdb:2KZU|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:5GRQ|rcsb pdb:5KDM|rcsb pdb:5Y18|rcsb pdb:5Y6O|reactome:R-HSA-3899300|reactome:R-HSA-6804757|reactome:R-HSA-9609690|reactome:R-HSA-9670095|reactome:R-HSA-9670613|reactome:R-HSA-9670615|refseq:NP_001135441.1|refseq:NP_001341.1|refseq:NP_001241646.1|dip:DIP-27628N refseq:NP_001001520.1|refseq:NP_116020.1|ensembl:ENSP00000483345|ensembl:ENST00000621835|ensembl:ENSP00000483702|ensembl:ENSG00000167674(gene)|ensembl:ENST00000616600(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030307"(positive regulation of cell growth)|interpro:IPR000313(PWWP)|interpro:IPR021567|interpro:IPR035441|interpro:IPR035496|interpro:IPR036218|mint:Q7Z4V5|rcsb pdb:3EAE|rcsb pdb:3QBY|rcsb pdb:3QJ6|rcsb pdb:6T3I - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lM3F/1ay7qvt8NkGWvgfSvBX1qQ9606 rogid:QUqOYvAwtXP0mk1KyQ++4y88lfI9606 rigid:VSxBgtiJWZil2fZ4Nb8xWrheH7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UER7 uniprotkb:Q9C005 intact:EBI-77321|ensembl:ENSP00000266000|ensembl:ENSP00000363668|ensembl:ENSP00000372539|ensembl:ENSP00000372681|ensembl:ENSP00000382014|ensembl:ENSP00000382281|ensembl:ENSP00000394108|ensembl:ENSP00000404376|ensembl:ENSP00000404623|ensembl:ENSP00000410772|uniprotkb:O14747|uniprotkb:O15141|uniprotkb:O15208|uniprotkb:Q9BWI3|uniprotkb:B4E1I3|uniprotkb:F5H082|uniprotkb:Q5STK9|uniprotkb:F5ANJ6|uniprotkb:F5ANJ7 intact:EBI-744973|uniprotkb:D6W578|ensembl:ENSP00000295066|ensembl:ENSP00000345837 psi-mi:daxx_human(display_long)|uniprotkb:DAXX(gene name)|psi-mi:DAXX(display_short)|uniprotkb:BING2(gene name synonym)|uniprotkb:DAP6(gene name synonym)|uniprotkb:Daxx(gene name synonym)|uniprotkb:Fas death domain-associated protein(gene name synonym)|uniprotkb:ETS1-associated protein 1(gene name synonym) psi-mi:dpy30_human(display_long)|uniprotkb:DPY30(gene name)|psi-mi:DPY30(display_short)|uniprotkb:Dpy-30-like protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477958|imex:IM-26985-313 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000206206(gene)|ensembl:ENSG00000206279(gene)|ensembl:ENSG00000227046(gene)|ensembl:ENSG00000231617(gene)|ensembl:ENSG00000204209(gene)|ensembl:ENST00000266000(transcript)|ensembl:ENST00000374542(transcript)|ensembl:ENST00000383062(transcript)|ensembl:ENST00000383194(transcript)|ensembl:ENST00000399060(transcript)|ensembl:ENST00000399344(transcript)|ensembl:ENST00000433482(transcript)|ensembl:ENST00000436311(transcript)|ensembl:ENST00000445009(transcript)|ensembl:ENST00000455860(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0072738"(cellular response to diamide)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903936"(cellular response to sodium arsenite)|interpro:IPR005012(Daxx protein)|interpro:IPR031333|interpro:IPR038298|mint:Q9UER7|rcsb pdb:2KQS|rcsb pdb:2KZS|rcsb pdb:2KZU|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:5GRQ|rcsb pdb:5KDM|rcsb pdb:5Y18|rcsb pdb:5Y6O|reactome:R-HSA-3899300|reactome:R-HSA-6804757|reactome:R-HSA-9609690|reactome:R-HSA-9670095|reactome:R-HSA-9670613|reactome:R-HSA-9670615|refseq:NP_001135441.1|refseq:NP_001341.1|refseq:NP_001241646.1|dip:DIP-27628N refseq:NP_115963.1|ensembl:ENSG00000162961(gene)|ensembl:ENST00000295066(transcript)|ensembl:ENST00000342166(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006348"|go:"GO:0016197"(endosomal transport)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|mint:Q9C005|rcsb pdb:3G36|rcsb pdb:4RIQ|rcsb pdb:4RT4|rcsb pdb:4RTA|rcsb pdb:6E2H|rcsb pdb:6PWV|reactome:R-HSA-3214841|reactome:R-HSA-8936459|refseq:NP_001308138.1|dip:DIP-34476N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lM3F/1ay7qvt8NkGWvgfSvBX1qQ9606 rogid:yC9NJhTfEIT+YyfWRSJLGbRsQkc9606 rigid:VSxBgtiJWZil2fZ4Nb8xWrheH7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UER7 uniprotkb:Q5JUX0 intact:EBI-77321|ensembl:ENSP00000266000|ensembl:ENSP00000363668|ensembl:ENSP00000372539|ensembl:ENSP00000372681|ensembl:ENSP00000382014|ensembl:ENSP00000382281|ensembl:ENSP00000394108|ensembl:ENSP00000404376|ensembl:ENSP00000404623|ensembl:ENSP00000410772|uniprotkb:O14747|uniprotkb:O15141|uniprotkb:O15208|uniprotkb:Q9BWI3|uniprotkb:B4E1I3|uniprotkb:F5H082|uniprotkb:Q5STK9|uniprotkb:F5ANJ6|uniprotkb:F5ANJ7 intact:EBI-1642527|uniprotkb:Q8N5D9|uniprotkb:B7Z8W2|uniprotkb:B2RUW3|ensembl:ENSP00000364054|ensembl:ENSP00000491179|ensembl:ENSP00000491624|ensembl:ENSP00000491751|ensembl:ENSP00000492344|ensembl:ENSP00000492381|ensembl:ENSP00000492795 psi-mi:daxx_human(display_long)|uniprotkb:DAXX(gene name)|psi-mi:DAXX(display_short)|uniprotkb:BING2(gene name synonym)|uniprotkb:DAP6(gene name synonym)|uniprotkb:Daxx(gene name synonym)|uniprotkb:Fas death domain-associated protein(gene name synonym)|uniprotkb:ETS1-associated protein 1(gene name synonym) psi-mi:spin3_human(display_long)|uniprotkb:SPIN3(gene name)|psi-mi:SPIN3(display_short)|uniprotkb:Spindlin-like protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477958|imex:IM-26985-313 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000206206(gene)|ensembl:ENSG00000206279(gene)|ensembl:ENSG00000227046(gene)|ensembl:ENSG00000231617(gene)|ensembl:ENSG00000204209(gene)|ensembl:ENST00000266000(transcript)|ensembl:ENST00000374542(transcript)|ensembl:ENST00000383062(transcript)|ensembl:ENST00000383194(transcript)|ensembl:ENST00000399060(transcript)|ensembl:ENST00000399344(transcript)|ensembl:ENST00000433482(transcript)|ensembl:ENST00000436311(transcript)|ensembl:ENST00000445009(transcript)|ensembl:ENST00000455860(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0072738"(cellular response to diamide)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903936"(cellular response to sodium arsenite)|interpro:IPR005012(Daxx protein)|interpro:IPR031333|interpro:IPR038298|mint:Q9UER7|rcsb pdb:2KQS|rcsb pdb:2KZS|rcsb pdb:2KZU|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:5GRQ|rcsb pdb:5KDM|rcsb pdb:5Y18|rcsb pdb:5Y6O|reactome:R-HSA-3899300|reactome:R-HSA-6804757|reactome:R-HSA-9609690|reactome:R-HSA-9670095|reactome:R-HSA-9670613|reactome:R-HSA-9670615|refseq:NP_001135441.1|refseq:NP_001341.1|refseq:NP_001241646.1|dip:DIP-27628N refseq:NP_001010862.2|refseq:XP_006724640.1|refseq:XP_006724641.1|refseq:XP_016884804.1|ensembl:ENSG00000204271(gene)|ensembl:ENST00000374919(transcript)|ensembl:ENST00000638257(transcript)|ensembl:ENST00000638289(transcript)|ensembl:ENST00000638386(transcript)|ensembl:ENST00000638712(transcript)|ensembl:ENST00000639007(transcript)|ensembl:ENST00000639605(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007276"(gamete generation)|go:"GO:0035064"(methylated histone binding)|interpro:IPR003671(Spindlin/spermiogenesis-specific protein)|interpro:IPR029567|interpro:IPR042567|mint:Q5JUX0|rcsb pdb:5A1H - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lM3F/1ay7qvt8NkGWvgfSvBX1qQ9606 rogid:Z4PHGiFUPGeFRxSjg6rzBFnXv7g9606 rigid:VSxBgtiJWZil2fZ4Nb8xWrheH7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UER7 uniprotkb:Q99417 intact:EBI-77321|ensembl:ENSP00000266000|ensembl:ENSP00000363668|ensembl:ENSP00000372539|ensembl:ENSP00000372681|ensembl:ENSP00000382014|ensembl:ENSP00000382281|ensembl:ENSP00000394108|ensembl:ENSP00000404376|ensembl:ENSP00000404623|ensembl:ENSP00000410772|uniprotkb:O14747|uniprotkb:O15141|uniprotkb:O15208|uniprotkb:Q9BWI3|uniprotkb:B4E1I3|uniprotkb:F5H082|uniprotkb:Q5STK9|uniprotkb:F5ANJ6|uniprotkb:F5ANJ7 intact:EBI-716185|intact:EBI-2559925|uniprotkb:Q5TA64|uniprotkb:Q96HE2|uniprotkb:B2R4N0|ensembl:ENSP00000380702 psi-mi:daxx_human(display_long)|uniprotkb:DAXX(gene name)|psi-mi:DAXX(display_short)|uniprotkb:BING2(gene name synonym)|uniprotkb:DAP6(gene name synonym)|uniprotkb:Daxx(gene name synonym)|uniprotkb:Fas death domain-associated protein(gene name synonym)|uniprotkb:ETS1-associated protein 1(gene name synonym) psi-mi:mycbp_human(display_long)|uniprotkb:Associate of Myc 1(gene name synonym)|uniprotkb:MYCBP(gene name)|psi-mi:MYCBP(display_short)|uniprotkb:AMY1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477958|imex:IM-26985-313 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000206206(gene)|ensembl:ENSG00000206279(gene)|ensembl:ENSG00000227046(gene)|ensembl:ENSG00000231617(gene)|ensembl:ENSG00000204209(gene)|ensembl:ENST00000266000(transcript)|ensembl:ENST00000374542(transcript)|ensembl:ENST00000383062(transcript)|ensembl:ENST00000383194(transcript)|ensembl:ENST00000399060(transcript)|ensembl:ENST00000399344(transcript)|ensembl:ENST00000433482(transcript)|ensembl:ENST00000436311(transcript)|ensembl:ENST00000445009(transcript)|ensembl:ENST00000455860(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0072738"(cellular response to diamide)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903936"(cellular response to sodium arsenite)|interpro:IPR005012(Daxx protein)|interpro:IPR031333|interpro:IPR038298|mint:Q9UER7|rcsb pdb:2KQS|rcsb pdb:2KZS|rcsb pdb:2KZU|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:5GRQ|rcsb pdb:5KDM|rcsb pdb:5Y18|rcsb pdb:5Y6O|reactome:R-HSA-3899300|reactome:R-HSA-6804757|reactome:R-HSA-9609690|reactome:R-HSA-9670095|reactome:R-HSA-9670613|reactome:R-HSA-9670615|refseq:NP_001135441.1|refseq:NP_001341.1|refseq:NP_001241646.1|dip:DIP-27628N refseq:NP_036465.2|ensembl:ENSG00000214114(gene)|ensembl:ENST00000397572(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007283"(spermatogenesis)|interpro:IPR026060|mint:Q99417|rcsb pdb:2YY0 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lM3F/1ay7qvt8NkGWvgfSvBX1qQ9606 rogid:jIStn1A10DDkgTuwVeKpDPJ6tIs9606 rigid:VSxBgtiJWZil2fZ4Nb8xWrheH7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UER7 uniprotkb:Q96HA7 intact:EBI-77321|ensembl:ENSP00000266000|ensembl:ENSP00000363668|ensembl:ENSP00000372539|ensembl:ENSP00000372681|ensembl:ENSP00000382014|ensembl:ENSP00000382281|ensembl:ENSP00000394108|ensembl:ENSP00000404376|ensembl:ENSP00000404623|ensembl:ENSP00000410772|uniprotkb:O14747|uniprotkb:O15141|uniprotkb:O15208|uniprotkb:Q9BWI3|uniprotkb:B4E1I3|uniprotkb:F5H082|uniprotkb:Q5STK9|uniprotkb:F5ANJ6|uniprotkb:F5ANJ7 intact:EBI-1052467|uniprotkb:Q13006|uniprotkb:Q9UGJ2|uniprotkb:B5MDP0|uniprotkb:C9JKB1|uniprotkb:C9JNV8|intact:EBI-28979102|ensembl:ENSP00000386239 psi-mi:daxx_human(display_long)|uniprotkb:DAXX(gene name)|psi-mi:DAXX(display_short)|uniprotkb:BING2(gene name synonym)|uniprotkb:DAP6(gene name synonym)|uniprotkb:Daxx(gene name synonym)|uniprotkb:Fas death domain-associated protein(gene name synonym)|uniprotkb:ETS1-associated protein 1(gene name synonym) psi-mi:tonsl_human(display_long)|uniprotkb:IKBR(gene name synonym)|uniprotkb:Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2(gene name synonym)|uniprotkb:Inhibitor of kappa B-related protein(gene name synonym)|uniprotkb:TONSL(gene name)|psi-mi:TONSL(display_short)|uniprotkb:NFKBIL2(gene name synonym)|uniprotkb:NF-kappa-B inhibitor-like protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477958|imex:IM-26985-313 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000206206(gene)|ensembl:ENSG00000206279(gene)|ensembl:ENSG00000227046(gene)|ensembl:ENSG00000231617(gene)|ensembl:ENSG00000204209(gene)|ensembl:ENST00000266000(transcript)|ensembl:ENST00000374542(transcript)|ensembl:ENST00000383062(transcript)|ensembl:ENST00000383194(transcript)|ensembl:ENST00000399060(transcript)|ensembl:ENST00000399344(transcript)|ensembl:ENST00000433482(transcript)|ensembl:ENST00000436311(transcript)|ensembl:ENST00000445009(transcript)|ensembl:ENST00000455860(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0072738"(cellular response to diamide)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903936"(cellular response to sodium arsenite)|interpro:IPR005012(Daxx protein)|interpro:IPR031333|interpro:IPR038298|mint:Q9UER7|rcsb pdb:2KQS|rcsb pdb:2KZS|rcsb pdb:2KZU|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:5GRQ|rcsb pdb:5KDM|rcsb pdb:5Y18|rcsb pdb:5Y6O|reactome:R-HSA-3899300|reactome:R-HSA-6804757|reactome:R-HSA-9609690|reactome:R-HSA-9670095|reactome:R-HSA-9670613|reactome:R-HSA-9670615|refseq:NP_001135441.1|refseq:NP_001341.1|refseq:NP_001241646.1|dip:DIP-27628N refseq:NP_038460.4|ensembl:ENSP00000386239|ensembl:ENSG00000160949(gene)|ensembl:ENST00000409379(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016604"(nuclear body)|go:"GO:0031297"(replication fork processing)|go:"GO:0042393"(histone binding)|go:"GO:0043596"(nuclear replication fork)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR002110(Ankyrin)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR020683|interpro:IPR032675|interpro:IPR036770|mint:Q96HA7|rcsb pdb:5JA4 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lM3F/1ay7qvt8NkGWvgfSvBX1qQ9606 rogid:Y06T7HJriv692FDbQzKyimJb6z09606 rigid:VSxBgtiJWZil2fZ4Nb8xWrheH7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UER7 uniprotkb:P06899 intact:EBI-77321|ensembl:ENSP00000266000|ensembl:ENSP00000363668|ensembl:ENSP00000372539|ensembl:ENSP00000372681|ensembl:ENSP00000382014|ensembl:ENSP00000382281|ensembl:ENSP00000394108|ensembl:ENSP00000404376|ensembl:ENSP00000404623|ensembl:ENSP00000410772|uniprotkb:O14747|uniprotkb:O15141|uniprotkb:O15208|uniprotkb:Q9BWI3|uniprotkb:B4E1I3|uniprotkb:F5H082|uniprotkb:Q5STK9|uniprotkb:F5ANJ6|uniprotkb:F5ANJ7 intact:EBI-6150252|uniprotkb:B2R4J4|uniprotkb:O60816|ensembl:ENSP00000342886|ensembl:ENSP00000476136 psi-mi:daxx_human(display_long)|uniprotkb:DAXX(gene name)|psi-mi:DAXX(display_short)|uniprotkb:BING2(gene name synonym)|uniprotkb:DAP6(gene name synonym)|uniprotkb:Daxx(gene name synonym)|uniprotkb:Fas death domain-associated protein(gene name synonym)|uniprotkb:ETS1-associated protein 1(gene name synonym) psi-mi:h2b1j_human(display_long)|uniprotkb:H2BC11(gene name)|psi-mi:H2BC11(display_short)|uniprotkb:H2BFR(gene name synonym)|uniprotkb:HIST1H2BJ(gene name synonym)|uniprotkb:Histone H2B.1(gene name synonym)|uniprotkb:Histone H2B.r(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477958|imex:IM-26985-313 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000206206(gene)|ensembl:ENSG00000206279(gene)|ensembl:ENSG00000227046(gene)|ensembl:ENSG00000231617(gene)|ensembl:ENSG00000204209(gene)|ensembl:ENST00000266000(transcript)|ensembl:ENST00000374542(transcript)|ensembl:ENST00000383062(transcript)|ensembl:ENST00000383194(transcript)|ensembl:ENST00000399060(transcript)|ensembl:ENST00000399344(transcript)|ensembl:ENST00000433482(transcript)|ensembl:ENST00000436311(transcript)|ensembl:ENST00000445009(transcript)|ensembl:ENST00000455860(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0072738"(cellular response to diamide)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903936"(cellular response to sodium arsenite)|interpro:IPR005012(Daxx protein)|interpro:IPR031333|interpro:IPR038298|mint:Q9UER7|rcsb pdb:2KQS|rcsb pdb:2KZS|rcsb pdb:2KZU|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:5GRQ|rcsb pdb:5KDM|rcsb pdb:5Y18|rcsb pdb:5Y6O|reactome:R-HSA-3899300|reactome:R-HSA-6804757|reactome:R-HSA-9609690|reactome:R-HSA-9670095|reactome:R-HSA-9670613|reactome:R-HSA-9670615|refseq:NP_001135441.1|refseq:NP_001341.1|refseq:NP_001241646.1|dip:DIP-27628N refseq:NP_066402.2|dip:DIP-421N|ensembl:ENSG00000124635(gene)|ensembl:ENST00000339812(transcript)|ensembl:ENST00000607124(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P06899|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WAA|rcsb pdb:3WTP|rcsb pdb:4CAY|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5FUG|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5VEY|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6JXD|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6YOV|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7K5X|rcsb pdb:3WA9|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lM3F/1ay7qvt8NkGWvgfSvBX1qQ9606 rogid:74GQlSjGG1Ez6Uog74VXPLryKBc9606 rigid:VSxBgtiJWZil2fZ4Nb8xWrheH7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UER7 uniprotkb:Q9H2P0 intact:EBI-77321|ensembl:ENSP00000266000|ensembl:ENSP00000363668|ensembl:ENSP00000372539|ensembl:ENSP00000372681|ensembl:ENSP00000382014|ensembl:ENSP00000382281|ensembl:ENSP00000394108|ensembl:ENSP00000404376|ensembl:ENSP00000404623|ensembl:ENSP00000410772|uniprotkb:O14747|uniprotkb:O15141|uniprotkb:O15208|uniprotkb:Q9BWI3|uniprotkb:B4E1I3|uniprotkb:F5H082|uniprotkb:Q5STK9|uniprotkb:F5ANJ6|uniprotkb:F5ANJ7 intact:EBI-1764854|uniprotkb:E1P5Y2|uniprotkb:O94881|uniprotkb:Q5BKU2|uniprotkb:Q9UG34|intact:EBI-28975656|ensembl:ENSP00000342905|ensembl:ENSP00000360662|ensembl:ENSP00000379346|ensembl:ENSP00000379349|ensembl:ENSP00000483881 psi-mi:daxx_human(display_long)|uniprotkb:DAXX(gene name)|psi-mi:DAXX(display_short)|uniprotkb:BING2(gene name synonym)|uniprotkb:DAP6(gene name synonym)|uniprotkb:Daxx(gene name synonym)|uniprotkb:Fas death domain-associated protein(gene name synonym)|uniprotkb:ETS1-associated protein 1(gene name synonym) psi-mi:adnp_human(display_long)|uniprotkb:ADNP(gene name)|psi-mi:ADNP(display_short)|uniprotkb:ADNP1(gene name synonym)|uniprotkb:KIAA0784(gene name synonym)|uniprotkb:Activity-dependent neuroprotective protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477958|imex:IM-26985-313 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000206206(gene)|ensembl:ENSG00000206279(gene)|ensembl:ENSG00000227046(gene)|ensembl:ENSG00000231617(gene)|ensembl:ENSG00000204209(gene)|ensembl:ENST00000266000(transcript)|ensembl:ENST00000374542(transcript)|ensembl:ENST00000383062(transcript)|ensembl:ENST00000383194(transcript)|ensembl:ENST00000399060(transcript)|ensembl:ENST00000399344(transcript)|ensembl:ENST00000433482(transcript)|ensembl:ENST00000436311(transcript)|ensembl:ENST00000445009(transcript)|ensembl:ENST00000455860(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0072738"(cellular response to diamide)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903936"(cellular response to sodium arsenite)|interpro:IPR005012(Daxx protein)|interpro:IPR031333|interpro:IPR038298|mint:Q9UER7|rcsb pdb:2KQS|rcsb pdb:2KZS|rcsb pdb:2KZU|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:5GRQ|rcsb pdb:5KDM|rcsb pdb:5Y18|rcsb pdb:5Y6O|reactome:R-HSA-3899300|reactome:R-HSA-6804757|reactome:R-HSA-9609690|reactome:R-HSA-9670095|reactome:R-HSA-9670613|reactome:R-HSA-9670615|refseq:NP_001135441.1|refseq:NP_001341.1|refseq:NP_001241646.1|dip:DIP-27628N refseq:NP_001269460.1|refseq:NP_001269461.1|refseq:XP_011527049.1|refseq:NP_056154.1|refseq:NP_852107.1|ensembl:ENSP00000342905|ensembl:ENSP00000360662|ensembl:ENSP00000379346|ensembl:ENSP00000379349|ensembl:ENSP00000483881|ensembl:ENSG00000101126(gene)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0033484"(nitric oxide homeostasis)|ensembl:ENST00000349014(transcript)|ensembl:ENST00000371602(transcript)|ensembl:ENST00000396029(transcript)|ensembl:ENST00000396032(transcript)|ensembl:ENST00000621696(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007614"(short-term memory)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010835"(regulation of protein ADP-ribosylation)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019934"(cGMP-mediated signaling)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042277"(peptide binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044849"(estrous cycle)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050805"(negative regulation of synaptic transmission)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR001356(Homeobox)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR038861|mint:Q9H2P0|refseq:XP_016883247.1|refseq:XP_016883248.1|refseq:NP_001334440.1|dip:DIP-47288N - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lM3F/1ay7qvt8NkGWvgfSvBX1qQ9606 rogid:QJTl6p2b0Lp7HnHP8sFd5Hv+WGk9606 rigid:VSxBgtiJWZil2fZ4Nb8xWrheH7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UER7 uniprotkb:Q9NWU2 intact:EBI-77321|ensembl:ENSP00000266000|ensembl:ENSP00000363668|ensembl:ENSP00000372539|ensembl:ENSP00000372681|ensembl:ENSP00000382014|ensembl:ENSP00000382281|ensembl:ENSP00000394108|ensembl:ENSP00000404376|ensembl:ENSP00000404623|ensembl:ENSP00000410772|uniprotkb:O14747|uniprotkb:O15141|uniprotkb:O15208|uniprotkb:Q9BWI3|uniprotkb:B4E1I3|uniprotkb:F5H082|uniprotkb:Q5STK9|uniprotkb:F5ANJ6|uniprotkb:F5ANJ7 intact:EBI-1051077|uniprotkb:Q8N5M5|uniprotkb:E1P5I3|ensembl:ENSP00000266069 psi-mi:daxx_human(display_long)|uniprotkb:DAXX(gene name)|psi-mi:DAXX(display_short)|uniprotkb:BING2(gene name synonym)|uniprotkb:DAP6(gene name synonym)|uniprotkb:Daxx(gene name synonym)|uniprotkb:Fas death domain-associated protein(gene name synonym)|uniprotkb:ETS1-associated protein 1(gene name synonym) psi-mi:gid8_human(display_long)|uniprotkb:GID8(gene name)|psi-mi:GID8(display_short)|uniprotkb:C20orf11(gene name synonym)|uniprotkb:Two hybrid-associated protein 1 with RanBPM(gene name synonym)|uniprotkb:TWA1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477958|imex:IM-26985-313 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000206206(gene)|ensembl:ENSG00000206279(gene)|ensembl:ENSG00000227046(gene)|ensembl:ENSG00000231617(gene)|ensembl:ENSG00000204209(gene)|ensembl:ENST00000266000(transcript)|ensembl:ENST00000374542(transcript)|ensembl:ENST00000383062(transcript)|ensembl:ENST00000383194(transcript)|ensembl:ENST00000399060(transcript)|ensembl:ENST00000399344(transcript)|ensembl:ENST00000433482(transcript)|ensembl:ENST00000436311(transcript)|ensembl:ENST00000445009(transcript)|ensembl:ENST00000455860(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0072738"(cellular response to diamide)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903936"(cellular response to sodium arsenite)|interpro:IPR005012(Daxx protein)|interpro:IPR031333|interpro:IPR038298|mint:Q9UER7|rcsb pdb:2KQS|rcsb pdb:2KZS|rcsb pdb:2KZU|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:5GRQ|rcsb pdb:5KDM|rcsb pdb:5Y18|rcsb pdb:5Y6O|reactome:R-HSA-3899300|reactome:R-HSA-6804757|reactome:R-HSA-9609690|reactome:R-HSA-9670095|reactome:R-HSA-9670613|reactome:R-HSA-9670615|refseq:NP_001135441.1|refseq:NP_001341.1|refseq:NP_001241646.1|dip:DIP-27628N refseq:NP_060366.1|ensembl:ENSG00000101193(gene)|ensembl:ENST00000266069(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030054"(cell junction)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR006595(CTLH, C-terminal to LisH motif)|interpro:IPR013144(CT11-RanBPM)|interpro:IPR024964|mint:Q9NWU2|rcsb pdb:7NSC - - comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lM3F/1ay7qvt8NkGWvgfSvBX1qQ9606 rogid:P0HsK72KT6OPKKw7lVSJ/FiY4CU9606 rigid:VSxBgtiJWZil2fZ4Nb8xWrheH7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UER7 uniprotkb:Q13185 intact:EBI-77321|ensembl:ENSP00000266000|ensembl:ENSP00000363668|ensembl:ENSP00000372539|ensembl:ENSP00000372681|ensembl:ENSP00000382014|ensembl:ENSP00000382281|ensembl:ENSP00000394108|ensembl:ENSP00000404376|ensembl:ENSP00000404623|ensembl:ENSP00000410772|uniprotkb:O14747|uniprotkb:O15141|uniprotkb:O15208|uniprotkb:Q9BWI3|uniprotkb:B4E1I3|uniprotkb:F5H082|uniprotkb:Q5STK9|uniprotkb:F5ANJ6|uniprotkb:F5ANJ7 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 psi-mi:daxx_human(display_long)|uniprotkb:DAXX(gene name)|psi-mi:DAXX(display_short)|uniprotkb:BING2(gene name synonym)|uniprotkb:DAP6(gene name synonym)|uniprotkb:Daxx(gene name synonym)|uniprotkb:Fas death domain-associated protein(gene name synonym)|uniprotkb:ETS1-associated protein 1(gene name synonym) psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477958|imex:IM-26985-313 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000206206(gene)|ensembl:ENSG00000206279(gene)|ensembl:ENSG00000227046(gene)|ensembl:ENSG00000231617(gene)|ensembl:ENSG00000204209(gene)|ensembl:ENST00000266000(transcript)|ensembl:ENST00000374542(transcript)|ensembl:ENST00000383062(transcript)|ensembl:ENST00000383194(transcript)|ensembl:ENST00000399060(transcript)|ensembl:ENST00000399344(transcript)|ensembl:ENST00000433482(transcript)|ensembl:ENST00000436311(transcript)|ensembl:ENST00000445009(transcript)|ensembl:ENST00000455860(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0072738"(cellular response to diamide)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903936"(cellular response to sodium arsenite)|interpro:IPR005012(Daxx protein)|interpro:IPR031333|interpro:IPR038298|mint:Q9UER7|rcsb pdb:2KQS|rcsb pdb:2KZS|rcsb pdb:2KZU|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:5GRQ|rcsb pdb:5KDM|rcsb pdb:5Y18|rcsb pdb:5Y6O|reactome:R-HSA-3899300|reactome:R-HSA-6804757|reactome:R-HSA-9609690|reactome:R-HSA-9670095|reactome:R-HSA-9670613|reactome:R-HSA-9670615|refseq:NP_001135441.1|refseq:NP_001341.1|refseq:NP_001241646.1|dip:DIP-27628N go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N - - comment:"author score: 27" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lM3F/1ay7qvt8NkGWvgfSvBX1qQ9606 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rigid:VSxBgtiJWZil2fZ4Nb8xWrheH7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UER7 uniprotkb:P45973 intact:EBI-77321|ensembl:ENSP00000266000|ensembl:ENSP00000363668|ensembl:ENSP00000372539|ensembl:ENSP00000372681|ensembl:ENSP00000382014|ensembl:ENSP00000382281|ensembl:ENSP00000394108|ensembl:ENSP00000404376|ensembl:ENSP00000404623|ensembl:ENSP00000410772|uniprotkb:O14747|uniprotkb:O15141|uniprotkb:O15208|uniprotkb:Q9BWI3|uniprotkb:B4E1I3|uniprotkb:F5H082|uniprotkb:Q5STK9|uniprotkb:F5ANJ6|uniprotkb:F5ANJ7 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 psi-mi:daxx_human(display_long)|uniprotkb:DAXX(gene name)|psi-mi:DAXX(display_short)|uniprotkb:BING2(gene name synonym)|uniprotkb:DAP6(gene name synonym)|uniprotkb:Daxx(gene name synonym)|uniprotkb:Fas death domain-associated protein(gene name synonym)|uniprotkb:ETS1-associated protein 1(gene name synonym) psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477958|imex:IM-26985-313 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000206206(gene)|ensembl:ENSG00000206279(gene)|ensembl:ENSG00000227046(gene)|ensembl:ENSG00000231617(gene)|ensembl:ENSG00000204209(gene)|ensembl:ENST00000266000(transcript)|ensembl:ENST00000374542(transcript)|ensembl:ENST00000383062(transcript)|ensembl:ENST00000383194(transcript)|ensembl:ENST00000399060(transcript)|ensembl:ENST00000399344(transcript)|ensembl:ENST00000433482(transcript)|ensembl:ENST00000436311(transcript)|ensembl:ENST00000445009(transcript)|ensembl:ENST00000455860(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0072738"(cellular response to diamide)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903936"(cellular response to sodium arsenite)|interpro:IPR005012(Daxx protein)|interpro:IPR031333|interpro:IPR038298|mint:Q9UER7|rcsb pdb:2KQS|rcsb pdb:2KZS|rcsb pdb:2KZU|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:5GRQ|rcsb pdb:5KDM|rcsb pdb:5Y18|rcsb pdb:5Y6O|reactome:R-HSA-3899300|reactome:R-HSA-6804757|reactome:R-HSA-9609690|reactome:R-HSA-9670095|reactome:R-HSA-9670613|reactome:R-HSA-9670615|refseq:NP_001135441.1|refseq:NP_001341.1|refseq:NP_001241646.1|dip:DIP-27628N go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N - - comment:"author score: 32" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lM3F/1ay7qvt8NkGWvgfSvBX1qQ9606 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rigid:VSxBgtiJWZil2fZ4Nb8xWrheH7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UER7 uniprotkb:P46100 intact:EBI-77321|ensembl:ENSP00000266000|ensembl:ENSP00000363668|ensembl:ENSP00000372539|ensembl:ENSP00000372681|ensembl:ENSP00000382014|ensembl:ENSP00000382281|ensembl:ENSP00000394108|ensembl:ENSP00000404376|ensembl:ENSP00000404623|ensembl:ENSP00000410772|uniprotkb:O14747|uniprotkb:O15141|uniprotkb:O15208|uniprotkb:Q9BWI3|uniprotkb:B4E1I3|uniprotkb:F5H082|uniprotkb:Q5STK9|uniprotkb:F5ANJ6|uniprotkb:F5ANJ7 intact:EBI-396461|ensembl:ENSP00000362441|ensembl:ENSP00000378967|uniprotkb:P51068|uniprotkb:Q15886|uniprotkb:Q59FB5|uniprotkb:Q59H31|uniprotkb:Q5H9A2|uniprotkb:Q5JWI4|uniprotkb:Q7Z2J1|uniprotkb:Q9H0Z1|uniprotkb:Q9NTS3|uniprotkb:D3DTE2 psi-mi:daxx_human(display_long)|uniprotkb:DAXX(gene name)|psi-mi:DAXX(display_short)|uniprotkb:BING2(gene name synonym)|uniprotkb:DAP6(gene name synonym)|uniprotkb:Daxx(gene name synonym)|uniprotkb:Fas death domain-associated protein(gene name synonym)|uniprotkb:ETS1-associated protein 1(gene name synonym) psi-mi:atrx_human(display_long)|uniprotkb:ATRX(gene name)|psi-mi:ATRX(display_short)|uniprotkb:RAD54L(gene name synonym)|uniprotkb:XH2(gene name synonym)|uniprotkb:ATP-dependent helicase ATRX(gene name synonym)|uniprotkb:X-linked helicase II(gene name synonym)|uniprotkb:X-linked nuclear protein(gene name synonym)|uniprotkb:Znf-HX(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477958|imex:IM-26985-313 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000206206(gene)|ensembl:ENSG00000206279(gene)|ensembl:ENSG00000227046(gene)|ensembl:ENSG00000231617(gene)|ensembl:ENSG00000204209(gene)|ensembl:ENST00000266000(transcript)|ensembl:ENST00000374542(transcript)|ensembl:ENST00000383062(transcript)|ensembl:ENST00000383194(transcript)|ensembl:ENST00000399060(transcript)|ensembl:ENST00000399344(transcript)|ensembl:ENST00000433482(transcript)|ensembl:ENST00000436311(transcript)|ensembl:ENST00000445009(transcript)|ensembl:ENST00000455860(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0072738"(cellular response to diamide)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903936"(cellular response to sodium arsenite)|interpro:IPR005012(Daxx protein)|interpro:IPR031333|interpro:IPR038298|mint:Q9UER7|rcsb pdb:2KQS|rcsb pdb:2KZS|rcsb pdb:2KZU|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:5GRQ|rcsb pdb:5KDM|rcsb pdb:5Y18|rcsb pdb:5Y6O|reactome:R-HSA-3899300|reactome:R-HSA-6804757|reactome:R-HSA-9609690|reactome:R-HSA-9670095|reactome:R-HSA-9670613|reactome:R-HSA-9670615|refseq:NP_001135441.1|refseq:NP_001341.1|refseq:NP_001241646.1|dip:DIP-27628N ensembl:ENSG00000085224(gene)|go:"GO:0015616"(DNA translocase activity)|ensembl:ENST00000373344(transcript)|ensembl:ENST00000395603(transcript)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006281"(DNA repair)|go:"GO:0006306"(DNA methylation)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0016604"(nuclear body)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010571"(positive regulation of nuclear cell cycle DNA replication)|go:"GO:0016605"(PML body)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030900"(forebrain development)|go:"GO:0031297"(replication fork processing)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035128"(post-embryonic forelimb morphogenesis)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042393"(histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060009"(Sertoli cell development)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070615"|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0099115"(chromosome, subtelomeric region)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900112"(regulation of histone H3-K9 trimethylation)|go:"GO:1901581"(negative regulation of telomeric RNA transcription from RNA pol II promoter)|go:"GO:1901582"(positive regulation of telomeric RNA transcription from RNA pol II promoter)|go:"GO:1904908"(negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR025766|interpro:IPR027417|interpro:IPR038718|interpro:IPR041430|mint:P46100|rcsb pdb:2JM1|rcsb pdb:2LBM|rcsb pdb:2LD1|rcsb pdb:3QL9|rcsb pdb:3QLA|rcsb pdb:3QLC|rcsb pdb:3QLN|rcsb pdb:4W5A|rcsb pdb:5GRQ|rcsb pdb:5Y18|rcsb pdb:5Y6O|rcsb pdb:6G0O|reactome:R-HSA-9670095|reactome:R-HSA-9670613|reactome:R-HSA-9670615|refseq:NP_000480.3|refseq:NP_612114.2|dip:DIP-31532N - - comment:"author score: 42" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lM3F/1ay7qvt8NkGWvgfSvBX1qQ9606 rogid:3t+VQYWuUjQQSuDSQ0Urst2hha09606 rigid:VSxBgtiJWZil2fZ4Nb8xWrheH7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UER7 uniprotkb:O14929 intact:EBI-77321|ensembl:ENSP00000266000|ensembl:ENSP00000363668|ensembl:ENSP00000372539|ensembl:ENSP00000372681|ensembl:ENSP00000382014|ensembl:ENSP00000382281|ensembl:ENSP00000394108|ensembl:ENSP00000404376|ensembl:ENSP00000404623|ensembl:ENSP00000410772|uniprotkb:O14747|uniprotkb:O15141|uniprotkb:O15208|uniprotkb:Q9BWI3|uniprotkb:B4E1I3|uniprotkb:F5H082|uniprotkb:Q5STK9|uniprotkb:F5ANJ6|uniprotkb:F5ANJ7 intact:EBI-2339359|uniprotkb:Q53SU4|uniprotkb:Q53QF0|uniprotkb:Q49A44|uniprotkb:Q6P594|uniprotkb:Q8WWB9|ensembl:ENSP00000264108 psi-mi:daxx_human(display_long)|uniprotkb:DAXX(gene name)|psi-mi:DAXX(display_short)|uniprotkb:BING2(gene name synonym)|uniprotkb:DAP6(gene name synonym)|uniprotkb:Daxx(gene name synonym)|uniprotkb:Fas death domain-associated protein(gene name synonym)|uniprotkb:ETS1-associated protein 1(gene name synonym) psi-mi:hat1_human(display_long)|uniprotkb:HAT1(gene name)|psi-mi:HAT1(display_short)|uniprotkb:KAT1(gene name synonym)|uniprotkb:Histone acetyltransferase 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477958|imex:IM-26985-313 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000206206(gene)|ensembl:ENSG00000206279(gene)|ensembl:ENSG00000227046(gene)|ensembl:ENSG00000231617(gene)|ensembl:ENSG00000204209(gene)|ensembl:ENST00000266000(transcript)|ensembl:ENST00000374542(transcript)|ensembl:ENST00000383062(transcript)|ensembl:ENST00000383194(transcript)|ensembl:ENST00000399060(transcript)|ensembl:ENST00000399344(transcript)|ensembl:ENST00000433482(transcript)|ensembl:ENST00000436311(transcript)|ensembl:ENST00000445009(transcript)|ensembl:ENST00000455860(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0072738"(cellular response to diamide)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903936"(cellular response to sodium arsenite)|interpro:IPR005012(Daxx protein)|interpro:IPR031333|interpro:IPR038298|mint:Q9UER7|rcsb pdb:2KQS|rcsb pdb:2KZS|rcsb pdb:2KZU|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:5GRQ|rcsb pdb:5KDM|rcsb pdb:5Y18|rcsb pdb:5Y6O|reactome:R-HSA-3899300|reactome:R-HSA-6804757|reactome:R-HSA-9609690|reactome:R-HSA-9670095|reactome:R-HSA-9670613|reactome:R-HSA-9670615|refseq:NP_001135441.1|refseq:NP_001341.1|refseq:NP_001241646.1|dip:DIP-27628N refseq:NP_003633.1|dip:DIP-52811N|ensembl:ENSG00000128708(gene)|ensembl:ENST00000264108(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006323"(DNA packaging)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006348"|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0007584"(response to nutrient)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR013523(Histone acetyltransferase HAT1, C-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017380(Histone acetyltransferase type B, catalytic subunit)|interpro:IPR019467|interpro:IPR037113|mint:O14929|rcsb pdb:2P0W|rcsb pdb:6VO5|reactome:R-HSA-3214847 - - comment:"author score: 57" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lM3F/1ay7qvt8NkGWvgfSvBX1qQ9606 rogid:80KgRaid3NeRfAUdTHMQ/r0VuGo9606 rigid:VSxBgtiJWZil2fZ4Nb8xWrheH7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UER7 uniprotkb:P62805 intact:EBI-77321|ensembl:ENSP00000266000|ensembl:ENSP00000363668|ensembl:ENSP00000372539|ensembl:ENSP00000372681|ensembl:ENSP00000382014|ensembl:ENSP00000382281|ensembl:ENSP00000394108|ensembl:ENSP00000404376|ensembl:ENSP00000404623|ensembl:ENSP00000410772|uniprotkb:O14747|uniprotkb:O15141|uniprotkb:O15208|uniprotkb:Q9BWI3|uniprotkb:B4E1I3|uniprotkb:F5H082|uniprotkb:Q5STK9|uniprotkb:F5ANJ6|uniprotkb:F5ANJ7 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:daxx_human(display_long)|uniprotkb:DAXX(gene name)|psi-mi:DAXX(display_short)|uniprotkb:BING2(gene name synonym)|uniprotkb:DAP6(gene name synonym)|uniprotkb:Daxx(gene name synonym)|uniprotkb:Fas death domain-associated protein(gene name synonym)|uniprotkb:ETS1-associated protein 1(gene name synonym) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477958|imex:IM-26985-313 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000206206(gene)|ensembl:ENSG00000206279(gene)|ensembl:ENSG00000227046(gene)|ensembl:ENSG00000231617(gene)|ensembl:ENSG00000204209(gene)|ensembl:ENST00000266000(transcript)|ensembl:ENST00000374542(transcript)|ensembl:ENST00000383062(transcript)|ensembl:ENST00000383194(transcript)|ensembl:ENST00000399060(transcript)|ensembl:ENST00000399344(transcript)|ensembl:ENST00000433482(transcript)|ensembl:ENST00000436311(transcript)|ensembl:ENST00000445009(transcript)|ensembl:ENST00000455860(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0072738"(cellular response to diamide)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903936"(cellular response to sodium arsenite)|interpro:IPR005012(Daxx protein)|interpro:IPR031333|interpro:IPR038298|mint:Q9UER7|rcsb pdb:2KQS|rcsb pdb:2KZS|rcsb pdb:2KZU|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:5GRQ|rcsb pdb:5KDM|rcsb pdb:5Y18|rcsb pdb:5Y6O|reactome:R-HSA-3899300|reactome:R-HSA-6804757|reactome:R-HSA-9609690|reactome:R-HSA-9670095|reactome:R-HSA-9670613|reactome:R-HSA-9670615|refseq:NP_001135441.1|refseq:NP_001341.1|refseq:NP_001241646.1|dip:DIP-27628N ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - comment:"author score: 82" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lM3F/1ay7qvt8NkGWvgfSvBX1qQ9606 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 rigid:VSxBgtiJWZil2fZ4Nb8xWrheH7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UER7 uniprotkb:P84243 intact:EBI-77321|ensembl:ENSP00000266000|ensembl:ENSP00000363668|ensembl:ENSP00000372539|ensembl:ENSP00000372681|ensembl:ENSP00000382014|ensembl:ENSP00000382281|ensembl:ENSP00000394108|ensembl:ENSP00000404376|ensembl:ENSP00000404623|ensembl:ENSP00000410772|uniprotkb:O14747|uniprotkb:O15141|uniprotkb:O15208|uniprotkb:Q9BWI3|uniprotkb:B4E1I3|uniprotkb:F5H082|uniprotkb:Q5STK9|uniprotkb:F5ANJ6|uniprotkb:F5ANJ7 intact:EBI-120658|uniprotkb:P06351|uniprotkb:P33155|uniprotkb:Q5VV55|uniprotkb:Q5VV56|uniprotkb:Q66I33|uniprotkb:Q9V3W4|ensembl:ENSP00000254810|ensembl:ENSP00000355778|ensembl:ENSP00000355780|ensembl:ENSP00000355781|ensembl:ENSP00000465813|ensembl:ENSP00000466020|ensembl:ENSP00000468714|ensembl:ENSP00000499275|ensembl:ENSP00000499385|ensembl:ENSP00000499800 psi-mi:daxx_human(display_long)|uniprotkb:DAXX(gene name)|psi-mi:DAXX(display_short)|uniprotkb:BING2(gene name synonym)|uniprotkb:DAP6(gene name synonym)|uniprotkb:Daxx(gene name synonym)|uniprotkb:Fas death domain-associated protein(gene name synonym)|uniprotkb:ETS1-associated protein 1(gene name synonym) psi-mi:h33_human(display_long)|uniprotkb:H3-3A(gene name)|psi-mi:H3-3A(display_short)|uniprotkb:H3-3B(gene name)|psi-mi:H3-3B(display_short)|uniprotkb:H3.3A(gene name synonym)|uniprotkb:H3.3B(gene name synonym)|uniprotkb:H3F3(gene name synonym)|uniprotkb:H3F3A(gene name synonym)|uniprotkb:H3F3B(gene name synonym)|uniprotkb:PP781(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477958|imex:IM-26985-313 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000206206(gene)|ensembl:ENSG00000206279(gene)|ensembl:ENSG00000227046(gene)|ensembl:ENSG00000231617(gene)|ensembl:ENSG00000204209(gene)|ensembl:ENST00000266000(transcript)|ensembl:ENST00000374542(transcript)|ensembl:ENST00000383062(transcript)|ensembl:ENST00000383194(transcript)|ensembl:ENST00000399060(transcript)|ensembl:ENST00000399344(transcript)|ensembl:ENST00000433482(transcript)|ensembl:ENST00000436311(transcript)|ensembl:ENST00000445009(transcript)|ensembl:ENST00000455860(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0072738"(cellular response to diamide)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903936"(cellular response to sodium arsenite)|interpro:IPR005012(Daxx protein)|interpro:IPR031333|interpro:IPR038298|mint:Q9UER7|rcsb pdb:2KQS|rcsb pdb:2KZS|rcsb pdb:2KZU|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:5GRQ|rcsb pdb:5KDM|rcsb pdb:5Y18|rcsb pdb:5Y6O|reactome:R-HSA-3899300|reactome:R-HSA-6804757|reactome:R-HSA-9609690|reactome:R-HSA-9670095|reactome:R-HSA-9670613|reactome:R-HSA-9670615|refseq:NP_001135441.1|refseq:NP_001341.1|refseq:NP_001241646.1|dip:DIP-27628N refseq:NP_002098.1|refseq:NP_005315.1|rcsb pdb:4H9N|rcsb pdb:3QL9|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:3QLA|rcsb pdb:3QLC|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4L58|rcsb pdb:4N4I|rcsb pdb:3WTP|rcsb pdb:4O62|rcsb pdb:4QQ4|rcsb pdb:4TMP|rcsb pdb:4GNE|rcsb pdb:4GNF|rcsb pdb:4U7T|rcsb pdb:4GNG|rcsb pdb:4W5A|rcsb pdb:4GU0|rcsb pdb:4GUR|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:4GUS|rcsb pdb:4GY5|rcsb pdb:5DWQ|rcsb pdb:5DX0|rcsb pdb:5JA4|rcsb pdb:5JJY|ensembl:ENSG00000132475(gene)|ensembl:ENSG00000163041(gene)|rcsb pdb:5JLB|rcsb pdb:5KDM|rcsb pdb:5X7X|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6HGT|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6J9J|rcsb pdb:6PZV|rcsb pdb:6QXZ|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6U04|rcsb pdb:7A08|reactome:R-HSA-427413|rcsb pdb:7CIZ|reactome:R-HSA-5250924|reactome:R-HSA-5334118|rcsb pdb:7CJ0|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-983231|rcsb pdb:7CWH|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-427359|reactome:R-HSA-427389|ensembl:ENST00000254810(transcript)|ensembl:ENST00000366813(transcript)|ensembl:ENST00000366815(transcript)|ensembl:ENST00000366816(transcript)|ensembl:ENST00000586607(transcript)|ensembl:ENST00000587560(transcript)|ensembl:ENST00000589599(transcript)|ensembl:ENST00000655399(transcript)|ensembl:ENST00000661429(transcript)|ensembl:ENST00000666609(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P84243|rcsb pdb:2L43|rcsb pdb:3ASK|rcsb pdb:3ASL|rcsb pdb:3AV2|rcsb pdb:3JVK|rcsb pdb:3MUK|rcsb pdb:3MUL|dip:DIP-40046N - - comment:"author score: 87" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lM3F/1ay7qvt8NkGWvgfSvBX1qQ9606 rogid:cRqA5/IBNfIbbxAnbwLqzXip20I9606 rigid:VSxBgtiJWZil2fZ4Nb8xWrheH7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UM82 uniprotkb:Q9NQC7 intact:EBI-744066|uniprotkb:O94857|uniprotkb:E1P626|ensembl:ENSP00000289431|ensembl:ENSP00000416799 intact:EBI-2117940|uniprotkb:O94934|uniprotkb:Q7L3N6|uniprotkb:Q96EH0|uniprotkb:Q9NZX9|ensembl:ENSP00000308928|ensembl:ENSP00000392025 psi-mi:spat2_human(display_long)|uniprotkb:SPATA2(gene name)|psi-mi:SPATA2(display_short)|uniprotkb:KIAA0757(gene name synonym)|uniprotkb:PD1(gene name synonym) psi-mi:cyld_human(display_long)|uniprotkb:Ubiquitin thioesterase CYLD(gene name synonym)|uniprotkb:CYLD(gene name)|psi-mi:CYLD(display_short)|uniprotkb:CYLD1(gene name synonym)|uniprotkb:KIAA0849(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease CYLD(gene name synonym)|uniprotkb:Deubiquitinating enzyme CYLD(gene name synonym)|uniprotkb:HSPC057(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25477949|imex:IM-26985-241 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001129245.1|refseq:NP_006029.1|refseq:XP_011527418.1|ensembl:ENSG00000158480(gene)|ensembl:ENST00000289431(transcript)|ensembl:ENST00000422556(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|refseq:XP_006723957.1|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1990108"(protein linear deubiquitination)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR029744|mint:Q9UM82|rcsb pdb:5LJM|rcsb pdb:5LJN refseq:NP_001035814.1|refseq:NP_001035877.1|refseq:NP_056062.1|refseq:XP_016878467.1|refseq:XP_016878469.1|go:"GO:0007049"(cell cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010803"(regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0005874"(microtubule)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032480"(negative regulation of type I interferon production)|go:"GO:0036064"(ciliary basal body)|go:"GO:0045087"(innate immune response)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0060544"(regulation of necroptotic process)|go:"GO:0061578"(Lys63-specific deubiquitinase activity)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070266"(necroptotic process)|go:"GO:0070423"(nucleotide-binding oligomerization domain containing signaling pathway)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097542"(ciliary tip)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|go:"GO:1902017"(regulation of cilium assembly)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1990108"(protein linear deubiquitination)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001242"(regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000938(Cytoskeleton-associated protein, CAP-Gly)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036859|interpro:IPR038765|mint:Q9NQC7|rcsb pdb:1IXD|rcsb pdb:1WHL|rcsb pdb:1WHM|rcsb pdb:2VHF|reactome:R-HSA-168638|reactome:R-HSA-5357786|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5689880|reactome:R-HSA-936440|ensembl:ENSG00000083799(gene)|ensembl:ENST00000311559(transcript)|ensembl:ENST00000427738(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|refseq:XP_005255869.1|refseq:XP_006721212.1|refseq:XP_011521209.1|refseq:XP_016878466.1|refseq:XP_016878468.1 - comment:"author score: 29" - figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:VwbVhr/GuqylbroxXXcpBpWAXvM9606 rogid:Z01woAwtDVaoNnAthw9tTrBqRao9606 rigid:aOkLBGg5B3k0CK8DgStG0dJWP1o false - tandem tag:n-n - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6PD62 uniprotkb:P50750 intact:EBI-1019583|uniprotkb:Q15015|uniprotkb:D3DQV8|ensembl:ENSP00000355013 intact:EBI-1383449|uniprotkb:Q5JU24|uniprotkb:Q5JU25|uniprotkb:Q5U006|uniprotkb:Q96TF1|ensembl:ENSP00000362361 psi-mi:ctr9_human(display_long)|uniprotkb:CTR9(gene name)|psi-mi:CTR9(display_short)|uniprotkb:KIAA0155(gene name synonym)|uniprotkb:SH2BP1(gene name synonym)|uniprotkb:SH2 domain-binding protein 1(gene name synonym) psi-mi:cdk9_human(display_long)|uniprotkb:CDK9(gene name)|psi-mi:CDK9(display_short)|uniprotkb:CDC2L4(gene name synonym)|uniprotkb:Cell division protein kinase 9(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PITALRE(gene name synonym)|uniprotkb:Cell division cycle 2-like protein kinase 4(gene name synonym)|uniprotkb:C-2K(gene name synonym)|uniprotkb:TAK(gene name synonym)|uniprotkb:Tat-associated kinase complex catalytic subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477883|imex:IM-26985-83 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055448.1|ensembl:ENSG00000198730(gene)|ensembl:ENST00000361367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001826"(inner cell mass cell differentiation)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001832"(blastocyst growth)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0035327"|go:"GO:0042169"(SH2 domain binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:2000653"(regulation of genetic imprinting)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031101|mint:Q6PD62|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|dip:DIP-31693N refseq:NP_001252.1|dip:DIP-29016N|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000136807(gene)|ensembl:ENST00000373264(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P50750|rcsb pdb:1PF6|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:zEFAxq/VxkK8za6qsK0gcU+EU8o9606 rogid:XSEmM4b5tp/WCJCJxnQYyP0stvM9606 rigid:3UGjbryuJ66BdhJGYY34O7yvcNk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6PD62 uniprotkb:Q14241 intact:EBI-1019583|uniprotkb:Q15015|uniprotkb:D3DQV8|ensembl:ENSP00000355013 intact:EBI-742350|uniprotkb:Q8IXH1|uniprotkb:B2R7Q8|ensembl:ENSP00000395574|ensembl:ENSP00000484196 psi-mi:ctr9_human(display_long)|uniprotkb:CTR9(gene name)|psi-mi:CTR9(display_short)|uniprotkb:KIAA0155(gene name synonym)|uniprotkb:SH2BP1(gene name synonym)|uniprotkb:SH2 domain-binding protein 1(gene name synonym) psi-mi:eloa1_human(display_long)|uniprotkb:ELOA(gene name)|psi-mi:ELOA(display_short)|uniprotkb:Elongin 110 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit A1(gene name synonym)|uniprotkb:SIII p110(gene name synonym)|uniprotkb:TCEB3(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 3(gene name synonym)|uniprotkb:MSTP059(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477883|imex:IM-26985-83 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055448.1|ensembl:ENSG00000198730(gene)|ensembl:ENST00000361367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001826"(inner cell mass cell differentiation)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001832"(blastocyst growth)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0035327"|go:"GO:0042169"(SH2 domain binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:2000653"(regulation of genetic imprinting)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031101|mint:Q6PD62|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|dip:DIP-31693N refseq:NP_003189.2|ensembl:ENSG00000011007(gene)|ensembl:ENST00000418390(transcript)|ensembl:ENST00000613537(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0070449"(elongin complex)|go:"GO:0090734"(site of DNA damage)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR010684(RNA polymerase II transcription factor SIII, subunit A)|interpro:IPR017923|interpro:IPR035441|mint:Q14241|rcsb pdb:4HFX|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:zEFAxq/VxkK8za6qsK0gcU+EU8o9606 rogid:5gE87SPNXNcx+LQDo1Jwt/t9yfI9606 rigid:3UGjbryuJ66BdhJGYY34O7yvcNk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6PD62 uniprotkb:Q15370 intact:EBI-1019583|uniprotkb:Q15015|uniprotkb:D3DQV8|ensembl:ENSP00000355013 intact:EBI-301238|ensembl:ENSP00000386652|uniprotkb:B7WPD3 psi-mi:ctr9_human(display_long)|uniprotkb:CTR9(gene name)|psi-mi:CTR9(display_short)|uniprotkb:KIAA0155(gene name synonym)|uniprotkb:SH2BP1(gene name synonym)|uniprotkb:SH2 domain-binding protein 1(gene name synonym) psi-mi:elob_human(display_long)|uniprotkb:ELOB(gene name)|psi-mi:ELOB(display_short)|uniprotkb:Elongin 18 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit B(gene name synonym)|uniprotkb:SIII p18(gene name synonym)|uniprotkb:TCEB2(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477883|imex:IM-26985-83 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055448.1|ensembl:ENSG00000198730(gene)|ensembl:ENST00000361367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001826"(inner cell mass cell differentiation)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001832"(blastocyst growth)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0035327"|go:"GO:0042169"(SH2 domain binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:2000653"(regulation of genetic imprinting)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031101|mint:Q6PD62|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|dip:DIP-31693N ensembl:ENSG00000103363(gene)|ensembl:ENST00000409906(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030891"(VCB complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070449"(elongin complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR039049|mint:Q15370|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2JZ3|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFY|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:4WQO|rcsb pdb:6HAX|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:6SIS|refseq:NP_009039.1|refseq:NP_996896.1|dip:DIP-29570N - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:zEFAxq/VxkK8za6qsK0gcU+EU8o9606 rogid:apX4QFpDC4Dz3MAs7tQ8+XFHx6I9606 rigid:3UGjbryuJ66BdhJGYY34O7yvcNk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6PD62 uniprotkb:A6NED2 intact:EBI-1019583|uniprotkb:Q15015|uniprotkb:D3DQV8|ensembl:ENSP00000355013 intact:EBI-21552314|ensembl:ENSP00000377801|ensembl:ENSP00000451963|uniprotkb:B2RTP9|uniprotkb:Q29RX6 psi-mi:ctr9_human(display_long)|uniprotkb:CTR9(gene name)|psi-mi:CTR9(display_short)|uniprotkb:KIAA0155(gene name synonym)|uniprotkb:SH2BP1(gene name synonym)|uniprotkb:SH2 domain-binding protein 1(gene name synonym) psi-mi:rccd1_human(display_long)|uniprotkb:RCCD1(gene name)|psi-mi:RCCD1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477883|imex:IM-26985-83 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055448.1|ensembl:ENSG00000198730(gene)|ensembl:ENST00000361367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001826"(inner cell mass cell differentiation)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001832"(blastocyst growth)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0035327"|go:"GO:0042169"(SH2 domain binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:2000653"(regulation of genetic imprinting)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031101|mint:Q6PD62|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|dip:DIP-31693N ensembl:ENSG00000166965(gene)|ensembl:ENST00000394258(transcript)|ensembl:ENST00000556618(transcript)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|mint:A6NED2|rcsb pdb:6F4R|rcsb pdb:6F4S|rcsb pdb:6F4T|refseq:NP_001017919.1|refseq:NP_291022.2 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:zEFAxq/VxkK8za6qsK0gcU+EU8o9606 rogid:pJ4TNM7dmfISs5RIVzio/hBYHp09606 rigid:3UGjbryuJ66BdhJGYY34O7yvcNk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6PD62 uniprotkb:Q15369 intact:EBI-1019583|uniprotkb:Q15015|uniprotkb:D3DQV8|ensembl:ENSP00000355013 intact:EBI-301231|uniprotkb:Q567Q6|ensembl:ENSP00000284811|ensembl:ENSP00000428074|ensembl:ENSP00000428171|ensembl:ENSP00000428334|ensembl:ENSP00000429596|ensembl:ENSP00000429906|ensembl:ENSP00000478121|uniprotkb:E5RGD9 psi-mi:ctr9_human(display_long)|uniprotkb:CTR9(gene name)|psi-mi:CTR9(display_short)|uniprotkb:KIAA0155(gene name synonym)|uniprotkb:SH2BP1(gene name synonym)|uniprotkb:SH2 domain-binding protein 1(gene name synonym) psi-mi:eloc_human(display_long)|uniprotkb:ELOC(gene name)|psi-mi:ELOC(display_short)|uniprotkb:Elongin 15 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit C(gene name synonym)|uniprotkb:SIII p15(gene name synonym)|uniprotkb:TCEB1(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477883|imex:IM-26985-83 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055448.1|ensembl:ENSG00000198730(gene)|ensembl:ENST00000361367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001826"(inner cell mass cell differentiation)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001832"(blastocyst growth)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0035327"|go:"GO:0042169"(SH2 domain binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:2000653"(regulation of genetic imprinting)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031101|mint:Q6PD62|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|dip:DIP-31693N refseq:NP_005639.1|refseq:NP_001191786.1|refseq:NP_001191787.1|refseq:NP_001191788.1|refseq:NP_001191789.1|refseq:NP_001191790.1|refseq:NP_001191791.1|refseq:NP_001191792.1|refseq:NP_001191793.1|ensembl:ENSG00000154582(gene)|ensembl:ENST00000284811(transcript)|ensembl:ENST00000518127(transcript)|ensembl:ENST00000519487(transcript)|ensembl:ENST00000520242(transcript)|ensembl:ENST00000522337(transcript)|ensembl:ENST00000523815(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0070449"(elongin complex)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|mint:Q15369|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|ensembl:ENST00000622804(transcript)|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:4WQO|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:6HAX|rcsb pdb:6GFY|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7N|rcsb pdb:6SIS|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-167200|refseq:XP_011515882.1|refseq:XP_011515883.1|dip:DIP-29571N - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:zEFAxq/VxkK8za6qsK0gcU+EU8o9606 rogid:Ngvkh3YoddZoutF3Vgwdi2b6xz49606 rigid:3UGjbryuJ66BdhJGYY34O7yvcNk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6PD62 uniprotkb:Q8WVC0 intact:EBI-1019583|uniprotkb:Q15015|uniprotkb:D3DQV8|ensembl:ENSP00000355013 intact:EBI-932432|uniprotkb:Q96N99|ensembl:ENSP00000299601 psi-mi:ctr9_human(display_long)|uniprotkb:CTR9(gene name)|psi-mi:CTR9(display_short)|uniprotkb:KIAA0155(gene name synonym)|uniprotkb:SH2BP1(gene name synonym)|uniprotkb:SH2 domain-binding protein 1(gene name synonym) psi-mi:leo1_human(display_long)|uniprotkb:LEO1(gene name)|psi-mi:LEO1(display_short)|uniprotkb:RDL(gene name synonym)|uniprotkb:Replicative senescence down-regulated leo1-like protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477883|imex:IM-26985-83 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055448.1|ensembl:ENSG00000198730(gene)|ensembl:ENST00000361367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001826"(inner cell mass cell differentiation)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001832"(blastocyst growth)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0035327"|go:"GO:0042169"(SH2 domain binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:2000653"(regulation of genetic imprinting)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031101|mint:Q6PD62|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|dip:DIP-31693N refseq:NP_001273359.1|refseq:NP_620147.1|dip:DIP-37885N|ensembl:ENSG00000166477(gene)|ensembl:ENST00000299601(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|interpro:IPR007149(Leo1-like protein)|mint:Q8WVC0|rcsb pdb:4M6T|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-201722|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654 - - comment:"author score: 79" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:zEFAxq/VxkK8za6qsK0gcU+EU8o9606 rogid:o0aaW4nxzWuPZ8/pMZpa9Qz9oEA9606 rigid:3UGjbryuJ66BdhJGYY34O7yvcNk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6PD62 uniprotkb:Q9GZS3 intact:EBI-1019583|uniprotkb:Q15015|uniprotkb:D3DQV8|ensembl:ENSP00000355013 intact:EBI-358545|uniprotkb:D3DW84|uniprotkb:Q6IA22|uniprotkb:Q7Z4X4|ensembl:ENSP00000267973|ensembl:ENSP00000453801 psi-mi:ctr9_human(display_long)|uniprotkb:CTR9(gene name)|psi-mi:CTR9(display_short)|uniprotkb:KIAA0155(gene name synonym)|uniprotkb:SH2BP1(gene name synonym)|uniprotkb:SH2 domain-binding protein 1(gene name synonym) psi-mi:wdr61_human(display_long)|uniprotkb:WDR61(gene name)|psi-mi:WDR61(display_short)|uniprotkb:Meiotic recombination REC14 protein homolog(gene name synonym)|uniprotkb:SKI8 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477883|imex:IM-26985-83 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055448.1|ensembl:ENSG00000198730(gene)|ensembl:ENST00000361367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001826"(inner cell mass cell differentiation)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001832"(blastocyst growth)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0035327"|go:"GO:0042169"(SH2 domain binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:2000653"(regulation of genetic imprinting)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031101|mint:Q6PD62|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|dip:DIP-31693N refseq:NP_079510.1|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9GZS3|rcsb pdb:3OW8|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-429958|reactome:R-HSA-674695|reactome:R-HSA-75955|ensembl:ENSG00000140395(gene)|ensembl:ENST00000267973(transcript)|ensembl:ENST00000558311(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0055087"(Ski complex)|reactome:R-HSA-8866654|refseq:XP_011520396.1|refseq:NP_001290176.1|refseq:NP_001290177.1|dip:DIP-36672N - - comment:"author score: 81" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:zEFAxq/VxkK8za6qsK0gcU+EU8o9606 rogid:yVcjv2BXXr3VFSR7OcJ/1u9L6gw9606 rigid:3UGjbryuJ66BdhJGYY34O7yvcNk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6PD62 uniprotkb:Q6P1J9 intact:EBI-1019583|uniprotkb:Q15015|uniprotkb:D3DQV8|ensembl:ENSP00000355013 intact:EBI-930143|uniprotkb:A6NLZ8|uniprotkb:Q6PK51|uniprotkb:Q96A07|uniprotkb:Q9H245|uniprotkb:Q9H5L7|uniprotkb:B2RBR2|ensembl:ENSP00000356405 psi-mi:ctr9_human(display_long)|uniprotkb:CTR9(gene name)|psi-mi:CTR9(display_short)|uniprotkb:KIAA0155(gene name synonym)|uniprotkb:SH2BP1(gene name synonym)|uniprotkb:SH2 domain-binding protein 1(gene name synonym) psi-mi:cdc73_human(display_long)|uniprotkb:CDC73(gene name)|psi-mi:CDC73(display_short)|uniprotkb:C1orf28(gene name synonym)|uniprotkb:HRPT2(gene name synonym)|uniprotkb:Cell division cycle protein 73 homolog(gene name synonym)|uniprotkb:Hyperparathyroidism 2 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477883|imex:IM-26985-83 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055448.1|ensembl:ENSG00000198730(gene)|ensembl:ENST00000361367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001826"(inner cell mass cell differentiation)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001832"(blastocyst growth)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0035327"|go:"GO:0042169"(SH2 domain binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:2000653"(regulation of genetic imprinting)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031101|mint:Q6PD62|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|dip:DIP-31693N refseq:NP_078805.3|dip:DIP-37884N|ensembl:ENSG00000134371(gene)|ensembl:ENST00000367435(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0031648"(protein destabilization)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR007852(RNA polymerase II accessory factor, Cdc73)|interpro:IPR031336|interpro:IPR032041|interpro:IPR038103|mint:Q6P1J9|rcsb pdb:5YDE|rcsb pdb:5YDF|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-201722|reactome:R-HSA-5632684|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654 - - comment:"author score: 112" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:zEFAxq/VxkK8za6qsK0gcU+EU8o9606 rogid:nuJ2kK0petj8iBr17I2BQzxcVmE9606 rigid:3UGjbryuJ66BdhJGYY34O7yvcNk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6PD62 uniprotkb:Q8N7H5 intact:EBI-1019583|uniprotkb:Q15015|uniprotkb:D3DQV8|ensembl:ENSP00000355013 intact:EBI-2607770|uniprotkb:O75239|uniprotkb:Q9H166|uniprotkb:Q9NUU9|ensembl:ENSP00000221265|uniprotkb:M0QX35 psi-mi:ctr9_human(display_long)|uniprotkb:CTR9(gene name)|psi-mi:CTR9(display_short)|uniprotkb:KIAA0155(gene name synonym)|uniprotkb:SH2BP1(gene name synonym)|uniprotkb:SH2 domain-binding protein 1(gene name synonym) psi-mi:paf1_human(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:PD2(gene name synonym)|uniprotkb:Pancreatic differentiation protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477883|imex:IM-26985-83 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055448.1|ensembl:ENSG00000198730(gene)|ensembl:ENST00000361367(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001826"(inner cell mass cell differentiation)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001832"(blastocyst growth)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0035327"|go:"GO:0042169"(SH2 domain binding)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:2000653"(regulation of genetic imprinting)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR031101|mint:Q6PD62|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|dip:DIP-31693N refseq:NP_061961.2|ensembl:ENSG00000006712(gene)|ensembl:ENST00000221265(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030054"(cell junction)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|mint:Q8N7H5|rcsb pdb:4M6T|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|refseq:NP_001243755.1|dip:DIP-48673N - - comment:"author score: 169" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:zEFAxq/VxkK8za6qsK0gcU+EU8o9606 rogid:5Bf9gSdxgaufI30DVL8QAyVLqNk9606 rigid:3UGjbryuJ66BdhJGYY34O7yvcNk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13620 uniprotkb:P84090 intact:EBI-456067|uniprotkb:Q6PIE4|uniprotkb:Q6UP07|uniprotkb:B3KVX4|uniprotkb:B7Z5K8|uniprotkb:Q7Z673|uniprotkb:Q9BY37|uniprotkb:Q9UEB7|uniprotkb:Q9UED7|uniprotkb:B1APK5|ensembl:ENSP00000505084|ensembl:ENSP00000505176|ensembl:ENSP00000506259 intact:EBI-711389|uniprotkb:P70659|uniprotkb:Q14259|ensembl:ENSP00000451080|uniprotkb:B2R5H2 psi-mi:cul4b_human(display_long)|uniprotkb:CUL4B(gene name)|psi-mi:CUL4B(display_short)|uniprotkb:KIAA0695(gene name synonym) psi-mi:erh_human(display_long)|uniprotkb:ERH(gene name)|psi-mi:ERH(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477916|imex:IM-26985-465 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073341.1|refseq:NP_003579.3|ensembl:ENST00000371322|ensembl:ENSP00000360373|ensembl:ENST00000371323|ensembl:ENSP00000360374|ensembl:ENSP00000505084|ensembl:ENSP00000506259|ensembl:ENSP00000505176|refseq:XP_011529702.1|dip:DIP-31609N|ensembl:ENSG00000158290(gene)|ensembl:ENST00000680673(transcript)|ensembl:ENST00000681253(transcript)|ensembl:ENST00000681652(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031175"(neuron projection development)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR033044|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13620|rcsb pdb:2DO7|rcsb pdb:4A0C|rcsb pdb:4A0L|rcsb pdb:4A64|reactome:R-HSA-110314 ensembl:ENSG00000100632(gene)|ensembl:ENST00000557016(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006213"(pyrimidine nucleoside metabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0030496"(midbody)|go:"GO:0034709"(methylosome)|interpro:IPR000781(Enhancer of rudimentary)|interpro:IPR035912|mint:P84090|rcsb pdb:1W9G|rcsb pdb:2NML|rcsb pdb:7CNC|refseq:NP_004441.1|dip:DIP-42473N - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:D75aMBt3GaBdpBt5Mxsxk7yiRVg9606 rogid:foMOmvZ9wQyH0rrzBB2YlQhrT0g9606 rigid:itTwcSvSx4esh8+uatIGfQJ5/60 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13620 uniprotkb:Q16777 intact:EBI-456067|uniprotkb:Q6PIE4|uniprotkb:Q6UP07|uniprotkb:B3KVX4|uniprotkb:B7Z5K8|uniprotkb:Q7Z673|uniprotkb:Q9BY37|uniprotkb:Q9UEB7|uniprotkb:Q9UED7|uniprotkb:B1APK5|ensembl:ENSP00000505084|ensembl:ENSP00000505176|ensembl:ENSP00000506259 intact:EBI-5325566|ensembl:ENSP00000332194|uniprotkb:Q6DRA7|uniprotkb:Q8IUE5 psi-mi:cul4b_human(display_long)|uniprotkb:CUL4B(gene name)|psi-mi:CUL4B(display_short)|uniprotkb:KIAA0695(gene name synonym) psi-mi:h2a2c_human(display_long)|uniprotkb:H2AC20(gene name)|psi-mi:H2AC20(display_short)|uniprotkb:H2A-clustered histone 20(gene name synonym)|uniprotkb:H2AFQ(gene name synonym)|uniprotkb:HIST2H2AC(gene name synonym)|uniprotkb:Histone H2A-GL101(gene name synonym)|uniprotkb:Histone H2A/q(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477916|imex:IM-26985-465 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073341.1|refseq:NP_003579.3|ensembl:ENST00000371322|ensembl:ENSP00000360373|ensembl:ENST00000371323|ensembl:ENSP00000360374|ensembl:ENSP00000505084|ensembl:ENSP00000506259|ensembl:ENSP00000505176|refseq:XP_011529702.1|dip:DIP-31609N|ensembl:ENSG00000158290(gene)|ensembl:ENST00000680673(transcript)|ensembl:ENST00000681253(transcript)|ensembl:ENST00000681652(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031175"(neuron projection development)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR033044|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13620|rcsb pdb:2DO7|rcsb pdb:4A0C|rcsb pdb:4A0L|rcsb pdb:4A64|reactome:R-HSA-110314 reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-5689603|ensembl:ENSG00000184260(gene)|ensembl:ENST00000331380(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:Q16777|rcsb pdb:6Y5E|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|refseq:NP_003508.1 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:D75aMBt3GaBdpBt5Mxsxk7yiRVg9606 rogid:Wejrpp9wK3GvA4ahJDVyEH+cwlQ9606 rigid:itTwcSvSx4esh8+uatIGfQJ5/60 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13620 uniprotkb:P61201 intact:EBI-456067|uniprotkb:Q6PIE4|uniprotkb:Q6UP07|uniprotkb:B3KVX4|uniprotkb:B7Z5K8|uniprotkb:Q7Z673|uniprotkb:Q9BY37|uniprotkb:Q9UEB7|uniprotkb:Q9UED7|uniprotkb:B1APK5|ensembl:ENSP00000505084|ensembl:ENSP00000505176|ensembl:ENSP00000506259 intact:EBI-1050386|uniprotkb:O88950|uniprotkb:Q15647|uniprotkb:Q6FGP4|uniprotkb:Q9BY54|uniprotkb:Q9R249|uniprotkb:Q9UNI2|uniprotkb:Q9UNQ5|ensembl:ENSP00000373553 psi-mi:cul4b_human(display_long)|uniprotkb:CUL4B(gene name)|psi-mi:CUL4B(display_short)|uniprotkb:KIAA0695(gene name synonym) psi-mi:csn2_human(display_long)|uniprotkb:JAB1-containing signalosome subunit 2(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 15(gene name synonym)|uniprotkb:Alien homolog(gene name synonym)|uniprotkb:COPS2(gene name)|psi-mi:COPS2(display_short)|uniprotkb:CSN2(gene name synonym)|uniprotkb:TRIP15(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477916|imex:IM-26985-465 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073341.1|refseq:NP_003579.3|ensembl:ENST00000371322|ensembl:ENSP00000360373|ensembl:ENST00000371323|ensembl:ENSP00000360374|ensembl:ENSP00000505084|ensembl:ENSP00000506259|ensembl:ENSP00000505176|refseq:XP_011529702.1|dip:DIP-31609N|ensembl:ENSG00000158290(gene)|ensembl:ENST00000680673(transcript)|ensembl:ENST00000681253(transcript)|ensembl:ENST00000681652(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031175"(neuron projection development)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR033044|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13620|rcsb pdb:2DO7|rcsb pdb:4A0C|rcsb pdb:4A0L|rcsb pdb:4A64|reactome:R-HSA-110314 refseq:NP_001137359.1|refseq:NP_004227.1|ensembl:ENSG00000166200(gene)|ensembl:ENST00000388901(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000338"(protein deneddylation)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0030182"(neuron differentiation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:1903507"(negative regulation of nucleic acid-templated transcription)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR036390|interpro:IPR037750|mint:P61201|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4WSN|rcsb pdb:6A73|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664|reactome:R-HSA-9013422|dip:DIP-42076N - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:D75aMBt3GaBdpBt5Mxsxk7yiRVg9606 rogid:MrlEHktIBvvcQux7Z7kqYJYgbbs9606 rigid:itTwcSvSx4esh8+uatIGfQJ5/60 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13620 uniprotkb:O43318 intact:EBI-456067|uniprotkb:Q6PIE4|uniprotkb:Q6UP07|uniprotkb:B3KVX4|uniprotkb:B7Z5K8|uniprotkb:Q7Z673|uniprotkb:Q9BY37|uniprotkb:Q9UEB7|uniprotkb:Q9UED7|uniprotkb:B1APK5|ensembl:ENSP00000505084|ensembl:ENSP00000505176|ensembl:ENSP00000506259 intact:EBI-358684|uniprotkb:O43317|uniprotkb:O43319|uniprotkb:Q9NZ70|uniprotkb:Q9NTR3|uniprotkb:E1P523|uniprotkb:Q5TDN2|uniprotkb:Q5TDN3|uniprotkb:B2RE27|uniprotkb:Q5TDT7|ensembl:ENSP00000358335 psi-mi:cul4b_human(display_long)|uniprotkb:CUL4B(gene name)|psi-mi:CUL4B(display_short)|uniprotkb:KIAA0695(gene name synonym) psi-mi:m3k7_human(display_long)|uniprotkb:MAP3K7(gene name)|psi-mi:MAP3K7(display_short)|uniprotkb:TAK1(gene name synonym)|uniprotkb:Transforming growth factor-beta-activated kinase 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477916|imex:IM-26985-465 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073341.1|refseq:NP_003579.3|ensembl:ENST00000371322|ensembl:ENSP00000360373|ensembl:ENST00000371323|ensembl:ENSP00000360374|ensembl:ENSP00000505084|ensembl:ENSP00000506259|ensembl:ENSP00000505176|refseq:XP_011529702.1|dip:DIP-31609N|ensembl:ENSG00000158290(gene)|ensembl:ENST00000680673(transcript)|ensembl:ENST00000681253(transcript)|ensembl:ENST00000681652(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031175"(neuron projection development)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR033044|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13620|rcsb pdb:2DO7|rcsb pdb:4A0C|rcsb pdb:4A0L|rcsb pdb:4A64|reactome:R-HSA-110314 refseq:NP_003179.1|refseq:NP_663304.1|refseq:NP_663305.1|refseq:NP_663306.1|go:"GO:0007252"(I-kappaB phosphorylation)|go:"GO:0007254"(JNK cascade)|go:"GO:0008349"(MAP kinase kinase kinase kinase activity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051403"(stress-activated MAPK cascade)|ensembl:ENSG00000135341(gene)|go:"GO:0070423"(nucleotide-binding oligomerization domain containing signaling pathway)|ensembl:ENST00000369329(transcript)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002726"(positive regulation of T cell cytokine production)|go:"GO:0002753"(cytoplasmic pattern recognition receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017421(Mitogen-activated protein kinase kinase kinase 7)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:O43318|rcsb pdb:2EVA|rcsb pdb:2YIY|rcsb pdb:4GS6|rcsb pdb:4L3P|rcsb pdb:4L52|rcsb pdb:4L53|rcsb pdb:4O91|rcsb pdb:5E7R|rcsb pdb:5GJD|rcsb pdb:5GJF|rcsb pdb:5GJG|rcsb pdb:5J7S|rcsb pdb:5J8I|rcsb pdb:5J9L|rcsb pdb:5JGA|rcsb pdb:5JGB|rcsb pdb:5JGD|rcsb pdb:5JH6|rcsb pdb:5JK3|rcsb pdb:5V5N|rcsb pdb:7NTH|rcsb pdb:7NTI|reactome:R-HSA-1169091|reactome:R-HSA-168638|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-4086398|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5357956|reactome:R-HSA-5607764|reactome:R-HSA-5689880|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9645460|reactome:R-HSA-975163|dip:DIP-27523N - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:D75aMBt3GaBdpBt5Mxsxk7yiRVg9606 rogid:U/W3xH9XPl6BIdCcfrw1gG/+n7Y9606 rigid:itTwcSvSx4esh8+uatIGfQJ5/60 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13620 uniprotkb:P16403 intact:EBI-456067|uniprotkb:Q6PIE4|uniprotkb:Q6UP07|uniprotkb:B3KVX4|uniprotkb:B7Z5K8|uniprotkb:Q7Z673|uniprotkb:Q9BY37|uniprotkb:Q9UEB7|uniprotkb:Q9UED7|uniprotkb:B1APK5|ensembl:ENSP00000505084|ensembl:ENSP00000505176|ensembl:ENSP00000506259 intact:EBI-358372|ensembl:ENSP00000339566|uniprotkb:A8K4I2 psi-mi:cul4b_human(display_long)|uniprotkb:CUL4B(gene name)|psi-mi:CUL4B(display_short)|uniprotkb:KIAA0695(gene name synonym) psi-mi:h12_human(display_long)|uniprotkb:H1-2(gene name)|psi-mi:H1-2(display_short)|uniprotkb:H1F2(gene name synonym)|uniprotkb:HIST1H1C(gene name synonym)|uniprotkb:Histone H1c(gene name synonym)|uniprotkb:Histone H1d(gene name synonym)|uniprotkb:Histone H1s-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477916|imex:IM-26985-465 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073341.1|refseq:NP_003579.3|ensembl:ENST00000371322|ensembl:ENSP00000360373|ensembl:ENST00000371323|ensembl:ENSP00000360374|ensembl:ENSP00000505084|ensembl:ENSP00000506259|ensembl:ENSP00000505176|refseq:XP_011529702.1|dip:DIP-31609N|ensembl:ENSG00000158290(gene)|ensembl:ENST00000680673(transcript)|ensembl:ENST00000681253(transcript)|ensembl:ENST00000681652(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031175"(neuron projection development)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR033044|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13620|rcsb pdb:2DO7|rcsb pdb:4A0C|rcsb pdb:4A0L|rcsb pdb:4A64|reactome:R-HSA-110314 refseq:NP_005310.1|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P16403|reactome:R-HSA-140342|reactome:R-HSA-2559584|ensembl:ENSG00000187837(gene)|ensembl:ENST00000343677(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|dip:DIP-36359N - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:D75aMBt3GaBdpBt5Mxsxk7yiRVg9606 rogid:eRT5bTyBJUg6nRANMRYZekT4N+g9606 rigid:itTwcSvSx4esh8+uatIGfQJ5/60 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13620 uniprotkb:Q99627 intact:EBI-456067|uniprotkb:Q6PIE4|uniprotkb:Q6UP07|uniprotkb:B3KVX4|uniprotkb:B7Z5K8|uniprotkb:Q7Z673|uniprotkb:Q9BY37|uniprotkb:Q9UEB7|uniprotkb:Q9UED7|uniprotkb:B1APK5|ensembl:ENSP00000505084|ensembl:ENSP00000505176|ensembl:ENSP00000506259 intact:EBI-2510102|ensembl:ENSP00000346340|uniprotkb:A8K1H6|uniprotkb:Q53QS9 psi-mi:cul4b_human(display_long)|uniprotkb:CUL4B(gene name)|psi-mi:CUL4B(display_short)|uniprotkb:KIAA0695(gene name synonym) psi-mi:csn8_human(display_long)|uniprotkb:COPS8(gene name)|psi-mi:COPS8(display_short)|uniprotkb:CSN8(gene name synonym)|uniprotkb:JAB1-containing signalosome subunit 8(gene name synonym)|uniprotkb:COP9 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477916|imex:IM-26985-465 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073341.1|refseq:NP_003579.3|ensembl:ENST00000371322|ensembl:ENSP00000360373|ensembl:ENST00000371323|ensembl:ENSP00000360374|ensembl:ENSP00000505084|ensembl:ENSP00000506259|ensembl:ENSP00000505176|refseq:XP_011529702.1|dip:DIP-31609N|ensembl:ENSG00000158290(gene)|ensembl:ENST00000680673(transcript)|ensembl:ENST00000681253(transcript)|ensembl:ENST00000681652(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031175"(neuron projection development)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR033044|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13620|rcsb pdb:2DO7|rcsb pdb:4A0C|rcsb pdb:4A0L|rcsb pdb:4A64|reactome:R-HSA-110314 ensembl:ENSG00000198612(gene)|ensembl:ENST00000354371(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010387"(COP9 signalosome assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR033205|interpro:IPR033464|mint:Q99627|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4WSN|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664|go:"GO:0006468"(protein phosphorylation)|refseq:NP_006701.1|refseq:NP_937832.1|dip:DIP-42075N - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:D75aMBt3GaBdpBt5Mxsxk7yiRVg9606 rogid:3L+8IdjEw+ZC5MERztdPAY2ww389606 rigid:itTwcSvSx4esh8+uatIGfQJ5/60 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13620 uniprotkb:Q9H9Q2 intact:EBI-456067|uniprotkb:Q6PIE4|uniprotkb:Q6UP07|uniprotkb:B3KVX4|uniprotkb:B7Z5K8|uniprotkb:Q7Z673|uniprotkb:Q9BY37|uniprotkb:Q9UEB7|uniprotkb:Q9UED7|uniprotkb:B1APK5|ensembl:ENSP00000505084|ensembl:ENSP00000505176|ensembl:ENSP00000506259 intact:EBI-2510162|ensembl:ENSP00000272995|ensembl:ENSP00000386567|uniprotkb:Q53S22|uniprotkb:Q5BJG3|uniprotkb:Q9H7V6 psi-mi:cul4b_human(display_long)|uniprotkb:CUL4B(gene name)|psi-mi:CUL4B(display_short)|uniprotkb:KIAA0695(gene name synonym) psi-mi:csn7b_human(display_long)|uniprotkb:COPS7B(gene name)|psi-mi:COPS7B(display_short)|uniprotkb:CSN7B(gene name synonym)|uniprotkb:JAB1-containing signalosome subunit 7b(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477916|imex:IM-26985-465 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073341.1|refseq:NP_003579.3|ensembl:ENST00000371322|ensembl:ENSP00000360373|ensembl:ENST00000371323|ensembl:ENSP00000360374|ensembl:ENSP00000505084|ensembl:ENSP00000506259|ensembl:ENSP00000505176|refseq:XP_011529702.1|dip:DIP-31609N|ensembl:ENSG00000158290(gene)|ensembl:ENST00000680673(transcript)|ensembl:ENST00000681253(transcript)|ensembl:ENST00000681652(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031175"(neuron projection development)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR033044|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13620|rcsb pdb:2DO7|rcsb pdb:4A0C|rcsb pdb:4A0L|rcsb pdb:4A64|reactome:R-HSA-110314 refseq:NP_001269879.1|refseq:NP_001269881.1|ensembl:ENSG00000144524(gene)|ensembl:ENST00000350033(transcript)|ensembl:ENST00000410024(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0010387"(COP9 signalosome assembly)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR041481|mint:Q9H9Q2|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|interpro:IPR027530|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664|refseq:NP_073567.1|refseq:XP_016860205.1|refseq:XP_016860206.1|dip:DIP-53525N - - comment:"author score: 33" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:D75aMBt3GaBdpBt5Mxsxk7yiRVg9606 rogid:Q4rrTMRm/aOT/uIBaELCKNCZd9c9606 rigid:itTwcSvSx4esh8+uatIGfQJ5/60 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13620 uniprotkb:Q9BT78 intact:EBI-456067|uniprotkb:Q6PIE4|uniprotkb:Q6UP07|uniprotkb:B3KVX4|uniprotkb:B7Z5K8|uniprotkb:Q7Z673|uniprotkb:Q9BY37|uniprotkb:Q9UEB7|uniprotkb:Q9UED7|uniprotkb:B1APK5|ensembl:ENSP00000505084|ensembl:ENSP00000505176|ensembl:ENSP00000506259 intact:EBI-742413|uniprotkb:Q561W7|uniprotkb:Q9NW31|uniprotkb:Q9Y677|uniprotkb:B3KN88|ensembl:ENSP00000264389|uniprotkb:B3KST5 psi-mi:cul4b_human(display_long)|uniprotkb:CUL4B(gene name)|psi-mi:CUL4B(display_short)|uniprotkb:KIAA0695(gene name synonym) psi-mi:csn4_human(display_long)|uniprotkb:COPS4(gene name)|psi-mi:COPS4(display_short)|uniprotkb:CSN4(gene name synonym)|uniprotkb:JAB1-containing signalosome subunit 4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477916|imex:IM-26985-465 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073341.1|refseq:NP_003579.3|ensembl:ENST00000371322|ensembl:ENSP00000360373|ensembl:ENST00000371323|ensembl:ENSP00000360374|ensembl:ENSP00000505084|ensembl:ENSP00000506259|ensembl:ENSP00000505176|refseq:XP_011529702.1|dip:DIP-31609N|ensembl:ENSG00000158290(gene)|ensembl:ENST00000680673(transcript)|ensembl:ENST00000681253(transcript)|ensembl:ENST00000681652(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031175"(neuron projection development)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR033044|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13620|rcsb pdb:2DO7|rcsb pdb:4A0C|rcsb pdb:4A0L|rcsb pdb:4A64|reactome:R-HSA-110314 ensembl:ENSG00000138663(gene)|refseq:NP_057213.2|refseq:NP_001244935.1|go:"GO:0016607"(nuclear speck)|go:"GO:0019784"(NEDD8-specific protease activity)|go:"GO:0030054"(cell junction)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037754|interpro:IPR040134|interpro:IPR041406|mint:Q9BT78|rcsb pdb:4D0P|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4WSN|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664|reactome:R-HSA-9013422|ensembl:ENST00000264389(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008180"(COP9 signalosome)|refseq:NP_001317656.1|dip:DIP-34516N - - comment:"author score: 35" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:D75aMBt3GaBdpBt5Mxsxk7yiRVg9606 rogid:onrZiPzG+bZvycmpDTZMtkPzCfQ9606 rigid:itTwcSvSx4esh8+uatIGfQJ5/60 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13620 uniprotkb:Q9UNS2 intact:EBI-456067|uniprotkb:Q6PIE4|uniprotkb:Q6UP07|uniprotkb:B3KVX4|uniprotkb:B7Z5K8|uniprotkb:Q7Z673|uniprotkb:Q9BY37|uniprotkb:Q9UEB7|uniprotkb:Q9UED7|uniprotkb:B1APK5|ensembl:ENSP00000505084|ensembl:ENSP00000505176|ensembl:ENSP00000506259 intact:EBI-350590|uniprotkb:O43191|uniprotkb:Q7LDR6|uniprotkb:B2R683|ensembl:ENSP00000268717|uniprotkb:B4DY81 psi-mi:cul4b_human(display_long)|uniprotkb:CUL4B(gene name)|psi-mi:CUL4B(display_short)|uniprotkb:KIAA0695(gene name synonym) psi-mi:csn3_human(display_long)|uniprotkb:COPS3(gene name)|psi-mi:COPS3(display_short)|uniprotkb:CSN3(gene name synonym)|uniprotkb:JAB1-containing signalosome subunit 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25477916|imex:IM-26985-465 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073341.1|refseq:NP_003579.3|ensembl:ENST00000371322|ensembl:ENSP00000360373|ensembl:ENST00000371323|ensembl:ENSP00000360374|ensembl:ENSP00000505084|ensembl:ENSP00000506259|ensembl:ENSP00000505176|refseq:XP_011529702.1|dip:DIP-31609N|ensembl:ENSG00000158290(gene)|ensembl:ENST00000680673(transcript)|ensembl:ENST00000681253(transcript)|ensembl:ENST00000681652(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010498"(proteasomal protein catabolic process)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031175"(neuron projection development)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031465"(Cul4B-RING E3 ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070914"(UV-damage excision repair)|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-8951664|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR033044|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13620|rcsb pdb:2DO7|rcsb pdb:4A0C|rcsb pdb:4A0L|rcsb pdb:4A64|reactome:R-HSA-110314 refseq:NP_001186054.1|refseq:NP_003644.2|ensembl:ENSG00000141030(gene)|ensembl:ENST00000268717(transcript)|go:"GO:0000338"(protein deneddylation)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008180"(COP9 signalosome)|go:"GO:0009416"(response to light stimulus)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR036390|interpro:IPR037753|mint:Q9UNS2|rcsb pdb:4D10|rcsb pdb:4D18|rcsb pdb:4WSN|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-5696394|reactome:R-HSA-6781823|reactome:R-HSA-8856825|reactome:R-HSA-8951664|rcsb pdb:6R6H|refseq:NP_001303283.1|refseq:NP_001303284.1|refseq:NP_001303285.1|refseq:NP_001303286.1|refseq:NP_001303287.1|refseq:XP_005256894.1|dip:DIP-32478N - - comment:"author score: 45" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:D75aMBt3GaBdpBt5Mxsxk7yiRVg9606 rogid:z6E/tPEo/ksVxD5Yyfo89t+ww989606 rigid:itTwcSvSx4esh8+uatIGfQJ5/60 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H2G4 uniprotkb:Q9GZR7 intact:EBI-947459|uniprotkb:O94799|uniprotkb:Q96DG7|uniprotkb:Q9BZW6|ensembl:ENSP00000364591 intact:EBI-713081|ensembl:ENSP00000481495|ensembl:ENSP00000482106|uniprotkb:E7EMJ4|uniprotkb:Q4V9L5 psi-mi:tsyl2_human(display_long)|uniprotkb:TSPYL2(gene name)|psi-mi:TSPYL2(display_short)|uniprotkb:Differentially-expressed nucleolar TGF-beta1 target protein(gene name synonym)|uniprotkb:Cell division autoantigen 1(gene name synonym)|uniprotkb:Cutaneous T-cell lymphoma-associated antigen se20-4(gene name synonym)|uniprotkb:Nuclear protein of 79 kDa(gene name synonym)|uniprotkb:CDA1(gene name synonym)|uniprotkb:DENTT(gene name synonym)|uniprotkb:TSPX(gene name synonym)|uniprotkb:HRIHFB2216(orf name) psi-mi:ddx24_human(display_long)|uniprotkb:DEAD box protein 24(gene name synonym)|uniprotkb:DDX24(gene name)|psi-mi:DDX24(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25478057|imex:IM-26985-317 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_071400.1|ensembl:ENSP00000364591|ensembl:ENSG00000184205(gene)|ensembl:ENST00000375442(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042393"(histone binding)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045859"(regulation of protein kinase activity)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q9H2G4|reactome:R-HSA-381038 ensembl:ENSG00000089737(gene)|ensembl:ENSG00000273761(gene)|ensembl:ENST00000613280(transcript)|ensembl:ENST00000621632(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR027417|mint:Q9GZR7|refseq:NP_065147.1|dip:DIP-47301N - comment:"author score: 45" - figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wVPRgfWOwBORcPzBZeyn9S9cqq09606 rogid:n9gQabTC50Y/LtGMAMFNVgj12as9606 rigid:kJNjbAEffzhhOBE33G3BVwT5DEc false - tandem tag:n-n - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P51610 uniprotkb:Q9BTC0 intact:EBI-396176|intact:EBI-2832627|uniprotkb:Q6P4G5|intact:EBI-12037257|intact:EBI-14324845|ensembl:ENSP00000309555|intact:EBI-12980473 intact:EBI-739985|uniprotkb:O15043|uniprotkb:A8MY65|uniprotkb:Q3ZTL7|uniprotkb:Q3ZTL8|uniprotkb:Q4VXS1|uniprotkb:Q4VXS2|uniprotkb:Q4VXV8|uniprotkb:Q96D72|uniprotkb:Q9BQW0|uniprotkb:Q9BW03|uniprotkb:Q9H4G6|uniprotkb:Q9H4G7|uniprotkb:Q9NTU8|uniprotkb:Q9NUM8|uniprotkb:Q9UFB6|uniprotkb:B9EH82|uniprotkb:Q4VXV9|uniprotkb:E1P5I1|intact:EBI-28975591|ensembl:ENSP00000266070|ensembl:ENSP00000378752 psi-mi:hcfc1_human(display_long)|uniprotkb:HCFC1(gene name)|psi-mi:HCFC1(display_short)|uniprotkb:HCF1(gene name synonym)|uniprotkb:C1 factor(gene name synonym)|uniprotkb:VP16 accessory protein(gene name synonym)|uniprotkb:VCAF(gene name synonym)|uniprotkb:CFF(gene name synonym)|uniprotkb:HFC1(gene name synonym) psi-mi:dido1_human(display_long)|uniprotkb:DIDO1(gene name)|psi-mi:DIDO1(display_short)|uniprotkb:Death-associated transcription factor 1(gene name synonym)|uniprotkb:C20orf158(gene name synonym)|uniprotkb:DATF1(gene name synonym)|uniprotkb:KIAA0333(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25478108|imex:IM-26985-393 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005325.2|refseq:XP_006724879.1|rcsb pdb:6MA1|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|reactome:R-HSA-2151201|reactome:R-HSA-3214847|reactome:R-HSA-5689603|ensembl:ENSG00000172534(gene)|ensembl:ENST00000310441(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019046"(release from viral latency)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR036116|interpro:IPR037854|interpro:IPR043536|mint:P51610|rcsb pdb:4GO6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:5LWV|dip:DIP-32955N ensembl:ENSP00000266070|ensembl:ENST00000354665|ensembl:ENSP00000346692|ensembl:ENST00000370366|ensembl:ENSP00000359391|ensembl:ENST00000370368|ensembl:ENSP00000359394|ensembl:ENST00000370371|ensembl:ENSP00000359397|ensembl:ENST00000395340|ensembl:ENSP00000378749|ensembl:ENSP00000378752|refseq:NP_001180298.1|refseq:NP_001180299.1|refseq:NP_071388.2|refseq:NP_149072.2|refseq:NP_542986.1|refseq:NP_542987.2|ensembl:ENSG00000101191(gene)|ensembl:ENST00000266070(transcript)|ensembl:ENST00000395343(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0097190"(apoptotic signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003618(Transcription elongation factor S-II, central region)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012921(Spen paralogue and orthologue C-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR033082|interpro:IPR036575|mint:Q9BTC0|rcsb pdb:2M3H|rcsb pdb:4L7X|reactome:R-HSA-1221632|refseq:XP_011526811.1 - comment:"author score: 27" - figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RzsCRe9l6md3DI87H4ZgdR9oBMI9606 rogid:xtp4cq/633PxqppXYlVvameuI7M9606 rigid:DUhgTz/WeUhtTQbVaHaU1i7/uIk false - tandem tag:n-n - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92785 uniprotkb:Q8NFD5 intact:EBI-359932|intact:EBI-1640314|uniprotkb:A8K7C9|ensembl:ENSP00000436901|uniprotkb:B4DT58 intact:EBI-679921|uniprotkb:Q5JRD1|uniprotkb:Q5VYC4|uniprotkb:Q8IZY8|uniprotkb:Q8TEV0|uniprotkb:Q8TF02|uniprotkb:Q99491|uniprotkb:Q9ULI5|intact:EBI-2560572|ensembl:ENSP00000055163 psi-mi:requ_human(display_long)|uniprotkb:DPF2(gene name)|psi-mi:DPF2(display_short)|uniprotkb:REQ(gene name synonym)|uniprotkb:UBID4(gene name synonym)|uniprotkb:Protein requiem(gene name synonym)|uniprotkb:Apoptosis response zinc finger protein(gene name synonym)|uniprotkb:D4, zinc and double PHD fingers family 2(gene name synonym)|uniprotkb:BAF45D(gene name synonym)|uniprotkb:BRG1-associated factor 45D(gene name synonym) psi-mi:ari1b_human(display_long)|uniprotkb:BAF250B(gene name synonym)|uniprotkb:Osa homolog 2(gene name synonym)|uniprotkb:p250R(gene name synonym)|uniprotkb:BRG1-binding protein hELD/OSA1(gene name synonym)|uniprotkb:BRG1-associated factor 250b(gene name synonym)|uniprotkb:ARID1B(gene name)|psi-mi:ARID1B(display_short)|uniprotkb:DAN15(gene name synonym)|uniprotkb:KIAA1235(gene name synonym)|uniprotkb:OSA2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478117|imex:IM-26985-319 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006259.1|ensembl:ENSG00000133884(gene)|ensembl:ENST00000528416(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0042393"(histone binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0062072"(H3K9me3 modified histone binding)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071565"(nBAF complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1905454"(negative regulation of myeloid progenitor cell differentiation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR019787|interpro:IPR025750|interpro:IPR036236|mint:Q92785|rcsb pdb:3IUF|rcsb pdb:5B79|rcsb pdb:5VDC|rcsb pdb:6LTH|rcsb pdb:6LTJ|dip:DIP-27575N refseq:NP_001333742.1|refseq:NP_059989.2|refseq:NP_065783.3|ensembl:ENSG00000049618(gene)|ensembl:ENST00000350026(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0035060"(brahma complex)|go:"GO:0043044"|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048096"|go:"GO:0071565"(nBAF complex)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR021906|interpro:IPR033388|interpro:IPR036431|interpro:IPR038040|mint:Q8NFD5|rcsb pdb:2CXY|rcsb pdb:2EH9|reactome:R-HSA-3214858|reactome:R-HSA-8939243 - - comment:"author score: 137" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Qe2VEvS8nCp6H3FSwm5dZCBibdU9606 rogid:BeWhuwPk5f6HN+yasFEJRpkbM6A9606 rigid:yesc4IjURR31+BvOQZdacDk+jro false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92785 uniprotkb:P51531 intact:EBI-359932|intact:EBI-1640314|uniprotkb:A8K7C9|ensembl:ENSP00000436901|uniprotkb:B4DT58 intact:EBI-679562|uniprotkb:B1ALG3|uniprotkb:B1ALG4|uniprotkb:D3DRH4|uniprotkb:D3DRH5|ensembl:ENSP00000265773|ensembl:ENSP00000371638 psi-mi:requ_human(display_long)|uniprotkb:DPF2(gene name)|psi-mi:DPF2(display_short)|uniprotkb:REQ(gene name synonym)|uniprotkb:UBID4(gene name synonym)|uniprotkb:Protein requiem(gene name synonym)|uniprotkb:Apoptosis response zinc finger protein(gene name synonym)|uniprotkb:D4, zinc and double PHD fingers family 2(gene name synonym)|uniprotkb:BAF45D(gene name synonym)|uniprotkb:BRG1-associated factor 45D(gene name synonym) psi-mi:smca2_human(display_long)|uniprotkb:ATP-dependent helicase SMARCA2(gene name synonym)|uniprotkb:SNF2-alpha(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2(gene name synonym)|uniprotkb:SMARCA2(gene name)|psi-mi:SMARCA2(display_short)|uniprotkb:BRM(gene name synonym)|uniprotkb:SNF2A(gene name synonym)|uniprotkb:SNF2L2(gene name synonym)|uniprotkb:BAF190B(gene name synonym)|uniprotkb:Protein brahma homolog(gene name synonym)|uniprotkb:BRG1-associated factor 190B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478117|imex:IM-26985-319 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006259.1|ensembl:ENSG00000133884(gene)|ensembl:ENST00000528416(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0042393"(histone binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0062072"(H3K9me3 modified histone binding)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071565"(nBAF complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1905454"(negative regulation of myeloid progenitor cell differentiation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR019787|interpro:IPR025750|interpro:IPR036236|mint:Q92785|rcsb pdb:3IUF|rcsb pdb:5B79|rcsb pdb:5VDC|rcsb pdb:6LTH|rcsb pdb:6LTJ|dip:DIP-27575N refseq:NP_003061.3|refseq:NP_620614.2|refseq:NP_001276325.1|refseq:NP_001276326.1|dip:DIP-29005N|ensembl:ENSG00000080503(gene)|ensembl:ENST00000349721(transcript)|ensembl:ENST00000382203(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007286"(spermatid development)|go:"GO:0007399"(nervous system development)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070615"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030088|interpro:IPR036427|interpro:IPR037259|interpro:IPR038718|mint:P51531|rcsb pdb:2DAT|rcsb pdb:4QY4|rcsb pdb:5DKC|rcsb pdb:5DKH|rcsb pdb:6EG2|rcsb pdb:6EG3|rcsb pdb:6HAX|rcsb pdb:6HAY|rcsb pdb:6HAZ|reactome:R-HSA-3214858|reactome:R-HSA-8939243 - - comment:"author score: 200" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Qe2VEvS8nCp6H3FSwm5dZCBibdU9606 rogid:DmQot4h4SmtqmUGBgF5ictTah289606 rigid:yesc4IjURR31+BvOQZdacDk+jro false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92785 uniprotkb:O14497 intact:EBI-359932|intact:EBI-1640314|uniprotkb:A8K7C9|ensembl:ENSP00000436901|uniprotkb:B4DT58 intact:EBI-637887|intact:EBI-28988406|ensembl:ENSP00000320485|uniprotkb:D3DPL1|uniprotkb:Q53FK9|uniprotkb:Q5T0W1|uniprotkb:Q5T0W2|uniprotkb:Q5T0W3|uniprotkb:Q8NFD6|uniprotkb:Q96T89|uniprotkb:Q9BY33|uniprotkb:Q9HBJ5|uniprotkb:Q9UPZ1 psi-mi:requ_human(display_long)|uniprotkb:DPF2(gene name)|psi-mi:DPF2(display_short)|uniprotkb:REQ(gene name synonym)|uniprotkb:UBID4(gene name synonym)|uniprotkb:Protein requiem(gene name synonym)|uniprotkb:Apoptosis response zinc finger protein(gene name synonym)|uniprotkb:D4, zinc and double PHD fingers family 2(gene name synonym)|uniprotkb:BAF45D(gene name synonym)|uniprotkb:BRG1-associated factor 45D(gene name synonym) psi-mi:ari1a_human(display_long)|uniprotkb:hELD(gene name synonym)|uniprotkb:SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1(gene name synonym)|uniprotkb:SWI/SNF complex protein p270(gene name synonym)|uniprotkb:B120(gene name synonym)|uniprotkb:SWI-like protein(gene name synonym)|uniprotkb:Osa homolog 1(gene name synonym)|uniprotkb:BRG1-associated factor 250(gene name synonym)|uniprotkb:BRG1-associated factor 250a(gene name synonym)|uniprotkb:ARID1A(gene name)|psi-mi:ARID1A(display_short)|uniprotkb:C1orf4(gene name synonym)|uniprotkb:SMARCF1(gene name synonym)|uniprotkb:OSA1(gene name synonym)|uniprotkb:BAF250(gene name synonym)|uniprotkb:BAF250A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478117|imex:IM-26985-319 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006259.1|ensembl:ENSG00000133884(gene)|ensembl:ENST00000528416(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0042393"(histone binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0062072"(H3K9me3 modified histone binding)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071565"(nBAF complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1905454"(negative regulation of myeloid progenitor cell differentiation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR019787|interpro:IPR025750|interpro:IPR036236|mint:Q92785|rcsb pdb:3IUF|rcsb pdb:5B79|rcsb pdb:5VDC|rcsb pdb:6LTH|rcsb pdb:6LTJ|dip:DIP-27575N reactome:R-HSA-3214858|reactome:R-HSA-8939243|go:"GO:0005634"(nucleus)|ensembl:ENSG00000117713(gene)|go:"GO:0005654"(nucleoplasm)|ensembl:ENST00000324856(transcript)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0035060"(brahma complex)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043044"|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048096"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021906|interpro:IPR030094|interpro:IPR033388|interpro:IPR036431|mint:O14497|rcsb pdb:1RYU|rcsb pdb:6LTH|rcsb pdb:6LTJ|refseq:NP_006006.3|refseq:NP_624361.1|dip:DIP-33016N|ensembl:ENSP00000320485|ensembl:ENST00000374152|ensembl:ENSP00000363267|ensembl:ENST00000457599|ensembl:ENSP00000387636 - - comment:"author score: 207" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Qe2VEvS8nCp6H3FSwm5dZCBibdU9606 rogid:C3ZRlsnBUZV6SBEbISRImamhzoQ9606 rigid:yesc4IjURR31+BvOQZdacDk+jro false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92785 uniprotkb:Q8WUZ0 intact:EBI-359932|intact:EBI-1640314|uniprotkb:A8K7C9|ensembl:ENSP00000436901|uniprotkb:B4DT58 intact:EBI-7850114|intact:EBI-28969068|ensembl:ENSP00000215115|uniprotkb:Q6PD89|uniprotkb:O43770|intact:MINT-4535839 psi-mi:requ_human(display_long)|uniprotkb:DPF2(gene name)|psi-mi:DPF2(display_short)|uniprotkb:REQ(gene name synonym)|uniprotkb:UBID4(gene name synonym)|uniprotkb:Protein requiem(gene name synonym)|uniprotkb:Apoptosis response zinc finger protein(gene name synonym)|uniprotkb:D4, zinc and double PHD fingers family 2(gene name synonym)|uniprotkb:BAF45D(gene name synonym)|uniprotkb:BRG1-associated factor 45D(gene name synonym) psi-mi:bcl7c_human(display_long)|uniprotkb:BCL7C(gene name)|psi-mi:BCL7C(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478117|imex:IM-26985-319 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006259.1|ensembl:ENSG00000133884(gene)|ensembl:ENST00000528416(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0042393"(histone binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0062072"(H3K9me3 modified histone binding)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071565"(nBAF complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1905454"(negative regulation of myeloid progenitor cell differentiation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR019787|interpro:IPR025750|interpro:IPR036236|mint:Q92785|rcsb pdb:3IUF|rcsb pdb:5B79|rcsb pdb:5VDC|rcsb pdb:6LTH|rcsb pdb:6LTJ|dip:DIP-27575N refseq:NP_001273455.1|ensembl:ENSP00000215115|ensembl:ENST00000380317|ensembl:ENSP00000369674|ensembl:ENSG00000099385(gene)|ensembl:ENST00000215115(transcript)|go:"GO:0006915"(apoptotic process)|interpro:IPR006804(BCL7, N-terminal)|mint:Q8WUZ0|refseq:NP_004756.2 - - comment:mint|comment:homomint|function:May play an anti-apoptotic role|comment:"author score: 269" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Qe2VEvS8nCp6H3FSwm5dZCBibdU9606 rogid:XuyDhxOhWHNVXmgi/WXLmCvKn409606 rigid:yesc4IjURR31+BvOQZdacDk+jro false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92785 uniprotkb:O94763 intact:EBI-359932|intact:EBI-1640314|uniprotkb:A8K7C9|ensembl:ENSP00000436901|uniprotkb:B4DT58 intact:EBI-357067|uniprotkb:A8K805|uniprotkb:Q9UNU3|intact:EBI-2683009|uniprotkb:H7BY42|uniprotkb:Q8TC23|ensembl:ENSP00000376097 psi-mi:requ_human(display_long)|uniprotkb:DPF2(gene name)|psi-mi:DPF2(display_short)|uniprotkb:REQ(gene name synonym)|uniprotkb:UBID4(gene name synonym)|uniprotkb:Protein requiem(gene name synonym)|uniprotkb:Apoptosis response zinc finger protein(gene name synonym)|uniprotkb:D4, zinc and double PHD fingers family 2(gene name synonym)|uniprotkb:BAF45D(gene name synonym)|uniprotkb:BRG1-associated factor 45D(gene name synonym) psi-mi:rmp_human(display_long)|uniprotkb:URI1(gene name)|psi-mi:URI1(display_short)|uniprotkb:C19orf2(gene name synonym)|uniprotkb:NNX3(gene name synonym)|uniprotkb:PPP1R19(gene name synonym)|uniprotkb:Protein NNX3(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 19(gene name synonym)|uniprotkb:RMP(gene name synonym)|uniprotkb:RNA polymerase II subunit 5-mediating protein(gene name synonym)|uniprotkb:URI(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478117|imex:IM-26985-319 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006259.1|ensembl:ENSG00000133884(gene)|ensembl:ENST00000528416(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0042393"(histone binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0062072"(H3K9me3 modified histone binding)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071565"(nBAF complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1905454"(negative regulation of myeloid progenitor cell differentiation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR019787|interpro:IPR025750|interpro:IPR036236|mint:Q92785|rcsb pdb:3IUF|rcsb pdb:5B79|rcsb pdb:5VDC|rcsb pdb:6LTH|rcsb pdb:6LTJ|dip:DIP-27575N refseq:NP_003787.2|ensembl:ENSG00000105176(gene)|refseq:NP_001239570.1|ensembl:ENST00000392271(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009615"(response to virus)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0019212"(phosphatase inhibitor activity)|go:"GO:0030425"(dendrite)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|mint:O94763 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Qe2VEvS8nCp6H3FSwm5dZCBibdU9606 rogid:izqLgjD5/WAkdmUp7K8hIQ+cGxE9606 rigid:yesc4IjURR31+BvOQZdacDk+jro false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92785 uniprotkb:P68032 intact:EBI-359932|intact:EBI-1640314|uniprotkb:A8K7C9|ensembl:ENSP00000436901|uniprotkb:B4DT58 intact:EBI-352273|uniprotkb:P04270|ensembl:ENSP00000290378 psi-mi:requ_human(display_long)|uniprotkb:DPF2(gene name)|psi-mi:DPF2(display_short)|uniprotkb:REQ(gene name synonym)|uniprotkb:UBID4(gene name synonym)|uniprotkb:Protein requiem(gene name synonym)|uniprotkb:Apoptosis response zinc finger protein(gene name synonym)|uniprotkb:D4, zinc and double PHD fingers family 2(gene name synonym)|uniprotkb:BAF45D(gene name synonym)|uniprotkb:BRG1-associated factor 45D(gene name synonym) psi-mi:actc_human(display_long)|uniprotkb:ACTC1(gene name)|psi-mi:ACTC1(display_short)|uniprotkb:ACTC(gene name synonym)|uniprotkb:Alpha-cardiac actin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478117|imex:IM-26985-319 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006259.1|ensembl:ENSG00000133884(gene)|ensembl:ENST00000528416(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0042393"(histone binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0062072"(H3K9me3 modified histone binding)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071565"(nBAF complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1905454"(negative regulation of myeloid progenitor cell differentiation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR019787|interpro:IPR025750|interpro:IPR036236|mint:Q92785|rcsb pdb:3IUF|rcsb pdb:5B79|rcsb pdb:5VDC|rcsb pdb:6LTH|rcsb pdb:6LTJ|dip:DIP-27575N refseq:NP_005150.1|ensembl:ENSG00000159251(gene)|ensembl:ENST00000290378(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031674"(I band)|go:"GO:0033275"(actin-myosin filament sliding)|go:"GO:0042493"|go:"GO:0044297"(cell body)|go:"GO:0045471"(response to ethanol)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0060047"(heart contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68032|reactome:R-HSA-390522|reactome:R-HSA-8980692|reactome:R-HSA-9013026 - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Qe2VEvS8nCp6H3FSwm5dZCBibdU9606 rogid:U/lKYqWUWMSC3fBHFaAcgzfk+3w9606 rigid:yesc4IjURR31+BvOQZdacDk+jro false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92785 uniprotkb:Q9NQG5 intact:EBI-359932|intact:EBI-1640314|uniprotkb:A8K7C9|ensembl:ENSP00000436901|uniprotkb:B4DT58 intact:EBI-747925|uniprotkb:Q1WDE7|uniprotkb:Q6PKF4|ensembl:ENSP00000362532 psi-mi:requ_human(display_long)|uniprotkb:DPF2(gene name)|psi-mi:DPF2(display_short)|uniprotkb:REQ(gene name synonym)|uniprotkb:UBID4(gene name synonym)|uniprotkb:Protein requiem(gene name synonym)|uniprotkb:Apoptosis response zinc finger protein(gene name synonym)|uniprotkb:D4, zinc and double PHD fingers family 2(gene name synonym)|uniprotkb:BAF45D(gene name synonym)|uniprotkb:BRG1-associated factor 45D(gene name synonym) psi-mi:rpr1b_human(display_long)|uniprotkb:RPRD1B(gene name)|psi-mi:RPRD1B(display_short)|uniprotkb:C20orf77(gene name synonym)|uniprotkb:CREPT(gene name synonym)|uniprotkb:Cell cycle-related and expression-elevated protein in tumor(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478117|imex:IM-26985-319 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006259.1|ensembl:ENSG00000133884(gene)|ensembl:ENST00000528416(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0042393"(histone binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0062072"(H3K9me3 modified histone binding)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071565"(nBAF complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1905454"(negative regulation of myeloid progenitor cell differentiation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR019787|interpro:IPR025750|interpro:IPR036236|mint:Q92785|rcsb pdb:3IUF|rcsb pdb:5B79|rcsb pdb:5VDC|rcsb pdb:6LTH|rcsb pdb:6LTJ|dip:DIP-27575N refseq:NP_067038.1|ensembl:ENSG00000101413(gene)|ensembl:ENST00000373433(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q9NQG5|rcsb pdb:4FLA|rcsb pdb:4FU3|rcsb pdb:4HFG|rcsb pdb:4NAD|rcsb pdb:4Q94|rcsb pdb:4Q96|reactome:R-HSA-6807505|dip:DIP-61537N - - comment:"author score: 29" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Qe2VEvS8nCp6H3FSwm5dZCBibdU9606 rogid:1P0sOiLV5eQXrRj+vENpc6L/z/Q9606 rigid:yesc4IjURR31+BvOQZdacDk+jro false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92785 uniprotkb:Q9BQE9 intact:EBI-359932|intact:EBI-1640314|uniprotkb:A8K7C9|ensembl:ENSP00000436901|uniprotkb:B4DT58 intact:EBI-2560588|uniprotkb:O43769|uniprotkb:Q6ZW75|uniprotkb:A8K226|uniprotkb:Q13845|uniprotkb:D3DXF0|ensembl:ENSP00000223368|uniprotkb:C9JWD3 psi-mi:requ_human(display_long)|uniprotkb:DPF2(gene name)|psi-mi:DPF2(display_short)|uniprotkb:REQ(gene name synonym)|uniprotkb:UBID4(gene name synonym)|uniprotkb:Protein requiem(gene name synonym)|uniprotkb:Apoptosis response zinc finger protein(gene name synonym)|uniprotkb:D4, zinc and double PHD fingers family 2(gene name synonym)|uniprotkb:BAF45D(gene name synonym)|uniprotkb:BRG1-associated factor 45D(gene name synonym) psi-mi:bcl7b_human(display_long)|uniprotkb:BCL7B(gene name)|psi-mi:BCL7B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478117|imex:IM-26985-319 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006259.1|ensembl:ENSG00000133884(gene)|ensembl:ENST00000528416(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0042393"(histone binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0062072"(H3K9me3 modified histone binding)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071565"(nBAF complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1905454"(negative regulation of myeloid progenitor cell differentiation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR019787|interpro:IPR025750|interpro:IPR036236|mint:Q92785|rcsb pdb:3IUF|rcsb pdb:5B79|rcsb pdb:5VDC|rcsb pdb:6LTH|rcsb pdb:6LTJ|dip:DIP-27575N refseq:NP_001184173.1|refseq:NP_001698.2|refseq:NP_001287990.1|ensembl:ENSG00000106635(gene)|ensembl:ENST00000223368(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0006915"(apoptotic process)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030154"(cell differentiation)|interpro:IPR006804(BCL7, N-terminal)|mint:Q9BQE9 - - comment:"author score: 43" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Qe2VEvS8nCp6H3FSwm5dZCBibdU9606 rogid:ZQ2u/rUGLSovFl0Kbvk7+w7/gCc9606 rigid:yesc4IjURR31+BvOQZdacDk+jro false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92785 uniprotkb:O75177 intact:EBI-359932|intact:EBI-1640314|uniprotkb:A8K7C9|ensembl:ENSP00000436901|uniprotkb:B4DT58 intact:EBI-744674|uniprotkb:Q5JXJ3|uniprotkb:Q8NE69|uniprotkb:Q9BR55|uniprotkb:Q9H4K6|uniprotkb:A6NNE3|uniprotkb:A8K620|uniprotkb:B3KWR8|uniprotkb:Q6MZV9|uniprotkb:Q6NTH3|uniprotkb:Q6XYD9|uniprotkb:E1P5H7|ensembl:ENSP00000333012 psi-mi:requ_human(display_long)|uniprotkb:DPF2(gene name)|psi-mi:DPF2(display_short)|uniprotkb:REQ(gene name synonym)|uniprotkb:UBID4(gene name synonym)|uniprotkb:Protein requiem(gene name synonym)|uniprotkb:Apoptosis response zinc finger protein(gene name synonym)|uniprotkb:D4, zinc and double PHD fingers family 2(gene name synonym)|uniprotkb:BAF45D(gene name synonym)|uniprotkb:BRG1-associated factor 45D(gene name synonym) psi-mi:crest_human(display_long)|uniprotkb:SYT homolog 1(gene name synonym)|uniprotkb:KIAA0693(gene name synonym)|uniprotkb:SS18L1(gene name)|psi-mi:SS18L1(display_short)|uniprotkb:CREST(gene name synonym)|uniprotkb:SS18-like protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478117|imex:IM-26985-319 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006259.1|ensembl:ENSG00000133884(gene)|ensembl:ENST00000528416(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0042393"(histone binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0062072"(H3K9me3 modified histone binding)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071565"(nBAF complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1905454"(negative regulation of myeloid progenitor cell differentiation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR019787|interpro:IPR025750|interpro:IPR036236|mint:Q92785|rcsb pdb:3IUF|rcsb pdb:5B79|rcsb pdb:5VDC|rcsb pdb:6LTH|rcsb pdb:6LTJ|dip:DIP-27575N refseq:NP_945173.1|refseq:XP_011527066.1|refseq:XP_011527069.1|ensembl:ENSG00000184402(gene)|ensembl:ENST00000331758(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0016358"(dendrite development)|go:"GO:0016604"(nuclear body)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0071565"(nBAF complex)|interpro:IPR007726(SSXT)|interpro:IPR044779|mint:O75177|refseq:NP_001288707.1|refseq:XP_005260448.1 - - comment:"author score: 85" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Qe2VEvS8nCp6H3FSwm5dZCBibdU9606 rogid:A7XGgvW0Roha0A4GgF5VvOC7dYs9606 rigid:yesc4IjURR31+BvOQZdacDk+jro false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92785 uniprotkb:Q15532 intact:EBI-359932|intact:EBI-1640314|uniprotkb:A8K7C9|ensembl:ENSP00000436901|uniprotkb:B4DT58 intact:EBI-2560599|uniprotkb:Q4VAX1|uniprotkb:Q16404|uniprotkb:B0YJ95|uniprotkb:Q9BXC6|ensembl:ENSP00000414516 psi-mi:requ_human(display_long)|uniprotkb:DPF2(gene name)|psi-mi:DPF2(display_short)|uniprotkb:REQ(gene name synonym)|uniprotkb:UBID4(gene name synonym)|uniprotkb:Protein requiem(gene name synonym)|uniprotkb:Apoptosis response zinc finger protein(gene name synonym)|uniprotkb:D4, zinc and double PHD fingers family 2(gene name synonym)|uniprotkb:BAF45D(gene name synonym)|uniprotkb:BRG1-associated factor 45D(gene name synonym) psi-mi:ssxt_human(display_long)|uniprotkb:SS18(gene name)|psi-mi:SS18(display_short)|uniprotkb:SSXT(gene name synonym)|uniprotkb:SYT(gene name synonym)|uniprotkb:Synovial sarcoma translocated to X chromosome protein(gene name synonym)|uniprotkb:Protein SYT(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478117|imex:IM-26985-319 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006259.1|ensembl:ENSG00000133884(gene)|ensembl:ENST00000528416(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0042393"(histone binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0062072"(H3K9me3 modified histone binding)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071565"(nBAF complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1905454"(negative regulation of myeloid progenitor cell differentiation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR019787|interpro:IPR025750|interpro:IPR036236|mint:Q92785|rcsb pdb:3IUF|rcsb pdb:5B79|rcsb pdb:5VDC|rcsb pdb:6LTH|rcsb pdb:6LTJ|dip:DIP-27575N refseq:NP_001007560.1|refseq:NP_001295130.1|refseq:NP_005628.2|ensembl:ENSG00000141380(gene)|ensembl:ENST00000415083(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0071564"(npBAF complex)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR007726(SSXT)|interpro:IPR044779|mint:Q15532|ensembl:ENST00000269137|ensembl:ENSP00000269137|ensembl:ENSP00000414516 - - comment:"author score: 85" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Qe2VEvS8nCp6H3FSwm5dZCBibdU9606 rogid:qECbpt+KgdXXqUWQnrsL7rwxznQ9606 rigid:yesc4IjURR31+BvOQZdacDk+jro false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92785 uniprotkb:Q4VC05 intact:EBI-359932|intact:EBI-1640314|uniprotkb:A8K7C9|ensembl:ENSP00000436901|uniprotkb:B4DT58 intact:EBI-359917|uniprotkb:Q13843|uniprotkb:B4DJN6|uniprotkb:B7ZB21|uniprotkb:Q14CT7|intact:EBI-2560561|ensembl:ENSP00000261822|ensembl:ENSP00000489305 psi-mi:requ_human(display_long)|uniprotkb:DPF2(gene name)|psi-mi:DPF2(display_short)|uniprotkb:REQ(gene name synonym)|uniprotkb:UBID4(gene name synonym)|uniprotkb:Protein requiem(gene name synonym)|uniprotkb:Apoptosis response zinc finger protein(gene name synonym)|uniprotkb:D4, zinc and double PHD fingers family 2(gene name synonym)|uniprotkb:BAF45D(gene name synonym)|uniprotkb:BRG1-associated factor 45D(gene name synonym) psi-mi:bcl7a_human(display_long)|uniprotkb:BCL7A(gene name)|psi-mi:BCL7A(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478117|imex:IM-26985-319 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006259.1|ensembl:ENSG00000133884(gene)|ensembl:ENST00000528416(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0042393"(histone binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0062072"(H3K9me3 modified histone binding)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071565"(nBAF complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1905454"(negative regulation of myeloid progenitor cell differentiation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR019787|interpro:IPR025750|interpro:IPR036236|mint:Q92785|rcsb pdb:3IUF|rcsb pdb:5B79|rcsb pdb:5VDC|rcsb pdb:6LTH|rcsb pdb:6LTJ|dip:DIP-27575N refseq:NP_001019979.1|refseq:NP_066273.1|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR006804(BCL7, N-terminal)|mint:Q4VC05|ensembl:ENSG00000110987(gene)|ensembl:ENSG00000282873(gene)|ensembl:ENST00000261822(transcript)|ensembl:ENST00000635403(transcript)|dip:DIP-27608N - - comment:"author score: 127" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Qe2VEvS8nCp6H3FSwm5dZCBibdU9606 rogid:ZEtiQWH57T+t+gCMVVPHAJUO10w9606 rigid:yesc4IjURR31+BvOQZdacDk+jro false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92785 uniprotkb:P51532 intact:EBI-359932|intact:EBI-1640314|uniprotkb:A8K7C9|ensembl:ENSP00000436901|uniprotkb:B4DT58 intact:EBI-302489|uniprotkb:O95052|uniprotkb:Q9HBD3|uniprotkb:B1A8Z4|uniprotkb:B1A8Z5|uniprotkb:B1A8Z6|uniprotkb:B1A8Z7|uniprotkb:E9PBR8|ensembl:ENSP00000343896|ensembl:ENSP00000395654 psi-mi:requ_human(display_long)|uniprotkb:DPF2(gene name)|psi-mi:DPF2(display_short)|uniprotkb:REQ(gene name synonym)|uniprotkb:UBID4(gene name synonym)|uniprotkb:Protein requiem(gene name synonym)|uniprotkb:Apoptosis response zinc finger protein(gene name synonym)|uniprotkb:D4, zinc and double PHD fingers family 2(gene name synonym)|uniprotkb:BAF45D(gene name synonym)|uniprotkb:BRG1-associated factor 45D(gene name synonym) psi-mi:smca4_human(display_long)|uniprotkb:SMARCA4(gene name)|psi-mi:SMARCA4(display_short)|uniprotkb:BRG1(gene name synonym)|uniprotkb:SNF2B(gene name synonym)|uniprotkb:SNF2L4(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA4(gene name synonym)|uniprotkb:SNF2-beta(gene name synonym)|uniprotkb:BAF190A(gene name synonym)|uniprotkb:Mitotic growth and transcription activator(gene name synonym)|uniprotkb:Protein BRG-1(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4(gene name synonym)|uniprotkb:Protein brahma homolog 1(gene name synonym)|uniprotkb:BRG1-associated factor 190A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478117|imex:IM-26985-319 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006259.1|ensembl:ENSG00000133884(gene)|ensembl:ENST00000528416(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0042393"(histone binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0062072"(H3K9me3 modified histone binding)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071565"(nBAF complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1905454"(negative regulation of myeloid progenitor cell differentiation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR019787|interpro:IPR025750|interpro:IPR036236|mint:Q92785|rcsb pdb:3IUF|rcsb pdb:5B79|rcsb pdb:5VDC|rcsb pdb:6LTH|rcsb pdb:6LTJ|dip:DIP-27575N refseq:NP_001122316.1|refseq:NP_003063.2|refseq:NP_001122317.1|refseq:NP_001122318.1|refseq:NP_001122319.1|refseq:NP_001122320.1|dip:DIP-24249N|refseq:XP_016882654.1|refseq:XP_016882655.1|refseq:XP_016882656.1|refseq:XP_016882657.1|ensembl:ENSG00000127616(gene)|ensembl:ENST00000344626(transcript)|ensembl:ENST00000429416(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0002039"(p53 binding)|go:"GO:0003407"(neural retina development)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030100|interpro:IPR036427|interpro:IPR037259|interpro:IPR038718|mint:P51532|rcsb pdb:2GRC|rcsb pdb:2H60|rcsb pdb:3UVD|rcsb pdb:5DKD|rcsb pdb:5EA1|rcsb pdb:6BGH|rcsb pdb:6HR2|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6SY2|rcsb pdb:6ZS2|reactome:R-HSA-1266695|reactome:R-HSA-201722|reactome:R-HSA-3214858|reactome:R-HSA-3247509|reactome:R-HSA-8939243|reactome:R-HSA-9619665 - - comment:"author score: 172" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Qe2VEvS8nCp6H3FSwm5dZCBibdU9606 rogid:Ztr+2IXfAxueSUaNYG2A47HoMes9606 rigid:yesc4IjURR31+BvOQZdacDk+jro false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92785 uniprotkb:Q6STE5 intact:EBI-359932|intact:EBI-1640314|uniprotkb:A8K7C9|ensembl:ENSP00000436901|uniprotkb:B4DT58 intact:EBI-465496|ensembl:ENSP00000262188|uniprotkb:Q75MJ2|uniprotkb:Q75MR8|uniprotkb:Q92926|uniprotkb:Q9BUH1|intact:EBI-488496|intact:EBI-1760029|uniprotkb:Q2YD86|uniprotkb:D3DX10 psi-mi:requ_human(display_long)|uniprotkb:DPF2(gene name)|psi-mi:DPF2(display_short)|uniprotkb:REQ(gene name synonym)|uniprotkb:UBID4(gene name synonym)|uniprotkb:Protein requiem(gene name synonym)|uniprotkb:Apoptosis response zinc finger protein(gene name synonym)|uniprotkb:D4, zinc and double PHD fingers family 2(gene name synonym)|uniprotkb:BAF45D(gene name synonym)|uniprotkb:BRG1-associated factor 45D(gene name synonym) psi-mi:smrd3_human(display_long)|uniprotkb:SMARCD3(gene name)|psi-mi:SMARCD3(display_short)|uniprotkb:BAF60C(gene name synonym)|uniprotkb:60 kDa BRG-1/Brm-associated factor subunit C(gene name synonym)|uniprotkb:BRG1-associated factor 60C(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478117|imex:IM-26985-319 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006259.1|ensembl:ENSG00000133884(gene)|ensembl:ENST00000528416(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0042393"(histone binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0062072"(H3K9me3 modified histone binding)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071565"(nBAF complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1905454"(negative regulation of myeloid progenitor cell differentiation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR019787|interpro:IPR025750|interpro:IPR036236|mint:Q92785|rcsb pdb:3IUF|rcsb pdb:5B79|rcsb pdb:5VDC|rcsb pdb:6LTH|rcsb pdb:6LTJ|dip:DIP-27575N ensembl:ENSG00000082014(gene)|ensembl:ENST00000262188(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003219"(cardiac right ventricle formation)|go:"GO:0003407"(neural retina development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR003121(SWIB/MDM2)|interpro:IPR019835|interpro:IPR036885|interpro:IPR038043|mint:Q6STE5|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|go:"GO:0016922"(nuclear receptor binding)|reactome:R-HSA-2426168|reactome:R-HSA-3214858|reactome:R-HSA-381340|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-8939243|reactome:R-HSA-9707564|reactome:R-HSA-9707616|reactome:R-HSA-2151201|refseq:NP_001003801.1|refseq:NP_001003802.1|refseq:NP_003069.2|dip:DIP-33012N - - comment:"author score: 174" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Qe2VEvS8nCp6H3FSwm5dZCBibdU9606 rogid:fCKGyz4ZneKj5VHia17wdMq6neI9606 rigid:yesc4IjURR31+BvOQZdacDk+jro false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92785 uniprotkb:O96019 intact:EBI-359932|intact:EBI-1640314|uniprotkb:A8K7C9|ensembl:ENSP00000436901|uniprotkb:B4DT58 intact:EBI-355018|uniprotkb:Q8TAE5|uniprotkb:Q9BVS8|uniprotkb:Q9H0W6|uniprotkb:B3KMN1|uniprotkb:D3DNR9|ensembl:ENSP00000397552 psi-mi:requ_human(display_long)|uniprotkb:DPF2(gene name)|psi-mi:DPF2(display_short)|uniprotkb:REQ(gene name synonym)|uniprotkb:UBID4(gene name synonym)|uniprotkb:Protein requiem(gene name synonym)|uniprotkb:Apoptosis response zinc finger protein(gene name synonym)|uniprotkb:D4, zinc and double PHD fingers family 2(gene name synonym)|uniprotkb:BAF45D(gene name synonym)|uniprotkb:BRG1-associated factor 45D(gene name synonym) psi-mi:acl6a_human(display_long)|uniprotkb:53 kDa BRG1-associated factor A(gene name synonym)|uniprotkb:Actin-related protein Baf53a(gene name synonym)|uniprotkb:ArpNbeta(gene name synonym)|uniprotkb:BAF53A(gene name synonym)|uniprotkb:ACTL6A(gene name)|psi-mi:ACTL6A(display_short)|uniprotkb:BAF53(gene name synonym)|uniprotkb:INO80K(gene name synonym)|uniprotkb:INO80 complex subunit K(gene name synonym)|uniprotkb:BRG1-associated factor 53A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478117|imex:IM-26985-319 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006259.1|ensembl:ENSG00000133884(gene)|ensembl:ENST00000528416(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0042393"(histone binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0062072"(H3K9me3 modified histone binding)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071565"(nBAF complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1905454"(negative regulation of myeloid progenitor cell differentiation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR019787|interpro:IPR025750|interpro:IPR036236|mint:Q92785|rcsb pdb:3IUF|rcsb pdb:5B79|rcsb pdb:5VDC|rcsb pdb:6LTH|rcsb pdb:6LTJ|dip:DIP-27575N refseq:NP_004292.1|refseq:NP_817126.1|refseq:NP_829888.1|ensembl:ENSG00000136518(gene)|ensembl:ENST00000429709(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0003407"(neural retina development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0021510"(spinal cord development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043044"|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0071564"(npBAF complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR043129|mint:O96019|rcsb pdb:6LTJ|reactome:R-HSA-3214847|reactome:R-HSA-3214858|go:"GO:0000785"(chromatin)|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8939243|ensembl:ENST00000392662|ensembl:ENSP00000376430|ensembl:ENSP00000397552|ensembl:ENST00000450518|ensembl:ENSP00000394014|dip:DIP-27565N - - comment:"author score: 175" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Qe2VEvS8nCp6H3FSwm5dZCBibdU9606 rogid:FV8zvQxf2aeHbwFNUpo9JOpj5U49606 rigid:yesc4IjURR31+BvOQZdacDk+jro false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92785 uniprotkb:Q8TAQ2 intact:EBI-359932|intact:EBI-1640314|uniprotkb:A8K7C9|ensembl:ENSP00000436901|uniprotkb:B4DT58 intact:EBI-357418|ensembl:ENSP00000267064|uniprotkb:Q92923|uniprotkb:Q96E12|uniprotkb:Q96GY4|intact:EBI-1759986|intact:EBI-1965079|uniprotkb:F8VTJ5|uniprotkb:Q59GV3 psi-mi:requ_human(display_long)|uniprotkb:DPF2(gene name)|psi-mi:DPF2(display_short)|uniprotkb:REQ(gene name synonym)|uniprotkb:UBID4(gene name synonym)|uniprotkb:Protein requiem(gene name synonym)|uniprotkb:Apoptosis response zinc finger protein(gene name synonym)|uniprotkb:D4, zinc and double PHD fingers family 2(gene name synonym)|uniprotkb:BAF45D(gene name synonym)|uniprotkb:BRG1-associated factor 45D(gene name synonym) psi-mi:smrc2_human(display_long)|uniprotkb:SMARCC2(gene name)|psi-mi:SMARCC2(display_short)|uniprotkb:BAF170(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2(gene name synonym)|uniprotkb:SWI/SNF complex 170 kDa subunit(gene name synonym)|uniprotkb:BRG1-associated factor 170(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478117|imex:IM-26985-319 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006259.1|ensembl:ENSG00000133884(gene)|ensembl:ENST00000528416(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0042393"(histone binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0062072"(H3K9me3 modified histone binding)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071565"(nBAF complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1905454"(negative regulation of myeloid progenitor cell differentiation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR019787|interpro:IPR025750|interpro:IPR036236|mint:Q92785|rcsb pdb:3IUF|rcsb pdb:5B79|rcsb pdb:5VDC|rcsb pdb:6LTH|rcsb pdb:6LTJ|dip:DIP-27575N ensembl:ENSG00000139613(gene)|ensembl:ENST00000267064(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR000953(Chromo domain)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR032448|interpro:IPR032450|interpro:IPR032451|interpro:IPR036388|interpro:IPR036420|interpro:IPR038044|mint:Q8TAQ2|rcsb pdb:6KAG|rcsb pdb:6LTH|rcsb pdb:6LTJ|reactome:R-HSA-3214858|reactome:R-HSA-8939243|refseq:NP_003066.2|refseq:NP_001123892.1|refseq:NP_620706.1|refseq:NP_001317217.1|dip:DIP-27611N - - comment:"author score: 195" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Qe2VEvS8nCp6H3FSwm5dZCBibdU9606 rogid:60gIB3J1YI/FzqVCzdoSg1Oj3ME9606 rigid:yesc4IjURR31+BvOQZdacDk+jro false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92785 uniprotkb:Q92925 intact:EBI-359932|intact:EBI-1640314|uniprotkb:A8K7C9|ensembl:ENSP00000436901|uniprotkb:B4DT58 intact:EBI-358441|uniprotkb:Q7L2I6|uniprotkb:Q9UHZ1|uniprotkb:A5PLL5|uniprotkb:A6NNQ7|uniprotkb:B4DV56|uniprotkb:B4E1R6|ensembl:ENSP00000392617 psi-mi:requ_human(display_long)|uniprotkb:DPF2(gene name)|psi-mi:DPF2(display_short)|uniprotkb:REQ(gene name synonym)|uniprotkb:UBID4(gene name synonym)|uniprotkb:Protein requiem(gene name synonym)|uniprotkb:Apoptosis response zinc finger protein(gene name synonym)|uniprotkb:D4, zinc and double PHD fingers family 2(gene name synonym)|uniprotkb:BAF45D(gene name synonym)|uniprotkb:BRG1-associated factor 45D(gene name synonym) psi-mi:smrd2_human(display_long)|uniprotkb:PRO2451(orf name)|uniprotkb:SMARCD2(gene name)|psi-mi:SMARCD2(display_short)|uniprotkb:BAF60B(gene name synonym)|uniprotkb:60 kDa BRG-1/Brm-associated factor subunit B(gene name synonym)|uniprotkb:BRG1-associated factor 60B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478117|imex:IM-26985-319 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006259.1|ensembl:ENSG00000133884(gene)|ensembl:ENST00000528416(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0042393"(histone binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0062072"(H3K9me3 modified histone binding)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071565"(nBAF complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1905454"(negative regulation of myeloid progenitor cell differentiation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR019787|interpro:IPR025750|interpro:IPR036236|mint:Q92785|rcsb pdb:3IUF|rcsb pdb:5B79|rcsb pdb:5VDC|rcsb pdb:6LTH|rcsb pdb:6LTJ|dip:DIP-27575N refseq:NP_001091896.1|dip:DIP-31182N|refseq:NP_001317369.1|ensembl:ENSG00000108604(gene)|ensembl:ENST00000448276(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR003121(SWIB/MDM2)|interpro:IPR019835|interpro:IPR030090|interpro:IPR036885|mint:Q92925|reactome:R-HSA-3214858|reactome:R-HSA-8939243 - - comment:"author score: 221" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Qe2VEvS8nCp6H3FSwm5dZCBibdU9606 rogid:n6YHBJ+cqEmVcXwMYsTZGOfL86A9606 rigid:yesc4IjURR31+BvOQZdacDk+jro false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92785 uniprotkb:Q96GM5 intact:EBI-359932|intact:EBI-1640314|uniprotkb:A8K7C9|ensembl:ENSP00000436901|uniprotkb:B4DT58 intact:EBI-358489|intact:EBI-1760001|ensembl:ENSP00000378414|uniprotkb:Q92924|uniprotkb:Q9Y635|intact:EBI-1965109|uniprotkb:A6NN27|intact:EBI-28976725 psi-mi:requ_human(display_long)|uniprotkb:DPF2(gene name)|psi-mi:DPF2(display_short)|uniprotkb:REQ(gene name synonym)|uniprotkb:UBID4(gene name synonym)|uniprotkb:Protein requiem(gene name synonym)|uniprotkb:Apoptosis response zinc finger protein(gene name synonym)|uniprotkb:D4, zinc and double PHD fingers family 2(gene name synonym)|uniprotkb:BAF45D(gene name synonym)|uniprotkb:BRG1-associated factor 45D(gene name synonym) psi-mi:smrd1_human(display_long)|uniprotkb:SMARCD1(gene name)|psi-mi:SMARCD1(display_short)|uniprotkb:BAF60A(gene name synonym)|uniprotkb:SWI/SNF complex 60 kDa subunit(gene name synonym)|uniprotkb:60 kDa BRG-1/Brm-associated factor subunit A(gene name synonym)|uniprotkb:BRG1-associated factor 60A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478117|imex:IM-26985-319 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006259.1|ensembl:ENSG00000133884(gene)|ensembl:ENST00000528416(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0042393"(histone binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0062072"(H3K9me3 modified histone binding)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071565"(nBAF complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1905454"(negative regulation of myeloid progenitor cell differentiation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR019787|interpro:IPR025750|interpro:IPR036236|mint:Q92785|rcsb pdb:3IUF|rcsb pdb:5B79|rcsb pdb:5VDC|rcsb pdb:6LTH|rcsb pdb:6LTJ|dip:DIP-27575N ensembl:ENSG00000066117(gene)|ensembl:ENST00000394963(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048096"|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071564"(npBAF complex)|refseq:NP_003067.3|refseq:NP_620710.2|ensembl:ENST00000381513|ensembl:ENSP00000370924|ensembl:ENSP00000378414|go:"GO:0071565"(nBAF complex)|interpro:IPR003121(SWIB/MDM2)|interpro:IPR019835|interpro:IPR036885|interpro:IPR038041|mint:Q96GM5|rcsb pdb:6LTH|rcsb pdb:6LTJ|reactome:R-HSA-3214858|reactome:R-HSA-8939243|dip:DIP-33390N - - comment:"author score: 225" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Qe2VEvS8nCp6H3FSwm5dZCBibdU9606 rogid:cwqYnl+J8glG8YjW1ps77Dd105Y9606 rigid:yesc4IjURR31+BvOQZdacDk+jro false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92785 uniprotkb:Q92922 intact:EBI-359932|intact:EBI-1640314|uniprotkb:A8K7C9|ensembl:ENSP00000436901|uniprotkb:B4DT58 intact:EBI-355653|uniprotkb:Q6P172|uniprotkb:Q8IWH2|uniprotkb:Q17RS0|ensembl:ENSP00000254480 psi-mi:requ_human(display_long)|uniprotkb:DPF2(gene name)|psi-mi:DPF2(display_short)|uniprotkb:REQ(gene name synonym)|uniprotkb:UBID4(gene name synonym)|uniprotkb:Protein requiem(gene name synonym)|uniprotkb:Apoptosis response zinc finger protein(gene name synonym)|uniprotkb:D4, zinc and double PHD fingers family 2(gene name synonym)|uniprotkb:BAF45D(gene name synonym)|uniprotkb:BRG1-associated factor 45D(gene name synonym) psi-mi:smrc1_human(display_long)|uniprotkb:SMARCC1(gene name)|psi-mi:SMARCC1(display_short)|uniprotkb:BAF155(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1(gene name synonym)|uniprotkb:SWI/SNF complex 155 kDa subunit(gene name synonym)|uniprotkb:BRG1-associated factor 155(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478117|imex:IM-26985-319 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006259.1|ensembl:ENSG00000133884(gene)|ensembl:ENST00000528416(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0042393"(histone binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0062072"(H3K9me3 modified histone binding)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071565"(nBAF complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1905454"(negative regulation of myeloid progenitor cell differentiation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR019787|interpro:IPR025750|interpro:IPR036236|mint:Q92785|rcsb pdb:3IUF|rcsb pdb:5B79|rcsb pdb:5VDC|rcsb pdb:6LTH|rcsb pdb:6LTJ|dip:DIP-27575N refseq:NP_003065.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR000953(Chromo domain)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR030087|interpro:IPR032448|interpro:IPR032450|interpro:IPR032451|interpro:IPR036388|interpro:IPR036420|mint:Q92922|rcsb pdb:2YUS|rcsb pdb:5GJK|rcsb pdb:6KZ7|rcsb pdb:6YXO|rcsb pdb:6YXP|reactome:R-HSA-3214858|reactome:R-HSA-8939243|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|ensembl:ENSG00000173473(gene)|ensembl:ENST00000254480(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001741"(XY body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030850"(prostate gland development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|ensembl:ENSP00000254480|dip:DIP-27545N|dip:DIP-33044N - - comment:"author score: 240" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Qe2VEvS8nCp6H3FSwm5dZCBibdU9606 rogid:Uv0bjPkUICLtOXJcETUXDTLIQhY9606 rigid:yesc4IjURR31+BvOQZdacDk+jro false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92785 uniprotkb:Q12824 intact:EBI-359932|intact:EBI-1640314|uniprotkb:A8K7C9|ensembl:ENSP00000436901|uniprotkb:B4DT58 intact:EBI-358419|uniprotkb:O75784|uniprotkb:O95474|uniprotkb:Q38GA1|uniprotkb:Q76N08|uniprotkb:Q9UBH2|ensembl:ENSP00000479330|ensembl:ENSP00000494049|uniprotkb:Q17S11 psi-mi:requ_human(display_long)|uniprotkb:DPF2(gene name)|psi-mi:DPF2(display_short)|uniprotkb:REQ(gene name synonym)|uniprotkb:UBID4(gene name synonym)|uniprotkb:Protein requiem(gene name synonym)|uniprotkb:Apoptosis response zinc finger protein(gene name synonym)|uniprotkb:D4, zinc and double PHD fingers family 2(gene name synonym)|uniprotkb:BAF45D(gene name synonym)|uniprotkb:BRG1-associated factor 45D(gene name synonym) psi-mi:snf5_human(display_long)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:INI1(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:BAF47(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478117|imex:IM-26985-319 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006259.1|ensembl:ENSG00000133884(gene)|ensembl:ENST00000528416(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0042393"(histone binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0062072"(H3K9me3 modified histone binding)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071565"(nBAF complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1905454"(negative regulation of myeloid progenitor cell differentiation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR019787|interpro:IPR025750|interpro:IPR036236|mint:Q92785|rcsb pdb:3IUF|rcsb pdb:5B79|rcsb pdb:5VDC|rcsb pdb:6LTH|rcsb pdb:6LTJ|dip:DIP-27575N mint:Q12824|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|rcsb pdb:5AJ1|rcsb pdb:5GJK|rcsb pdb:5L7A|rcsb pdb:5L7B|go:"GO:0007049"(cell cycle)|rcsb pdb:6AX5|go:"GO:0007399"(nervous system development)|rcsb pdb:6KAG|rcsb pdb:6KZ7|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6UCH|reactome:R-HSA-3214858|go:"GO:0008285"(negative regulation of cell population proliferation)|reactome:R-HSA-8939243|go:"GO:0015074"(DNA integration)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035060"(brahma complex)|go:"GO:0039692"(single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1900110"(negative regulation of histone H3-K9 dimethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR006939(SNF5/SMARCB1/INI1)|interpro:IPR017393(SWI/SNF chromatin-remodeling complex, component hSNF5/Ini1)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|refseq:NP_001007469.1|refseq:NP_003064.2|ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|ensembl:ENST00000618915(transcript)|ensembl:ENST00000644036(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0001741"(XY body)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-27550N - - comment:"author score: 259" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Qe2VEvS8nCp6H3FSwm5dZCBibdU9606 rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I9606 rigid:yesc4IjURR31+BvOQZdacDk+jro false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H410 uniprotkb:Q8NG31 intact:EBI-1001144|uniprotkb:E1P5U9|uniprotkb:Q5JW56|uniprotkb:Q9H8P4|ensembl:ENSP00000362855|ensembl:ENSP00000389810|uniprotkb:Q5JW55|uniprotkb:B4DWT2 intact:EBI-1001161|intact:EBI-2555927|uniprotkb:Q8NHE1|uniprotkb:Q8WXA6|uniprotkb:Q9HCK2|uniprotkb:Q9NR92|ensembl:ENSP00000335463 psi-mi:dsn1_human(display_long)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)|uniprotkb:C20orf172(gene name synonym)|uniprotkb:MIS13(gene name synonym) psi-mi:knl1_human(display_long)|uniprotkb:KNL1(gene name)|psi-mi:KNL1(display_short)|uniprotkb:ALL1-fused gene from chromosome 15q14 protein(gene name synonym)|uniprotkb:Bub-linking kinetochore protein(gene name synonym)|uniprotkb:CASC5(gene name synonym)|uniprotkb:Cancer susceptibility candidate gene 5 protein(gene name synonym)|uniprotkb:Cancer/testis antigen 29(gene name synonym)|uniprotkb:KIAA1570(gene name synonym)|uniprotkb:Kinetochore-null protein 1(gene name synonym)|uniprotkb:Protein CASC5(gene name synonym)|uniprotkb:Protein D40/AF15q14(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478203|imex:IM-26985-163 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138789.1|refseq:NP_001138787.1|refseq:NP_001138788.1|refseq:NP_079194.3|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-68877|reactome:R-HSA-9648025|rcsb pdb:5LSK|ensembl:ENSG00000149636(gene)|ensembl:ENST00000373750(transcript)|ensembl:ENST00000426836(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000939"(inner kinetochore)|go:"GO:0001650"(fibrillar center)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0051301"(cell division)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|mint:Q9H410|rcsb pdb:5LSI|rcsb pdb:5LSJ|refseq:NP_001138790.1|refseq:XP_006723939.1 ensembl:ENSG00000137812(gene)|ensembl:ENST00000346991(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001675"(acrosome assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016604"(nuclear body)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|interpro:IPR037388|interpro:IPR040850|interpro:IPR043651|mint:Q8NG31|rcsb pdb:3SI5|rcsb pdb:4A1G|rcsb pdb:4NF9|rcsb pdb:4NFA|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_653091.3|refseq:NP_733468.3|ensembl:ENSP00000335463|ensembl:ENST00000399668|ensembl:ENSP00000382576|dip:DIP-36474N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:cJ0wCtpLS+YkMj83k/SubkpHwuE9606 rogid:VrKgxXm7DGkpFhJjZ98oQhkr5Eo9606 rigid:j5NH0tZdQDFYETz4NkWgpW3+fgo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H410 uniprotkb:Q8NBT2 intact:EBI-1001144|uniprotkb:E1P5U9|uniprotkb:Q5JW56|uniprotkb:Q9H8P4|ensembl:ENSP00000362855|ensembl:ENSP00000389810|uniprotkb:Q5JW55|uniprotkb:B4DWT2 intact:EBI-999900|uniprotkb:C9JGC4|ensembl:ENSP00000465075|uniprotkb:B4DZZ7 psi-mi:dsn1_human(display_long)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)|uniprotkb:C20orf172(gene name synonym)|uniprotkb:MIS13(gene name synonym) psi-mi:spc24_human(display_long)|uniprotkb:SPBC24(gene name synonym)|uniprotkb:SPC24(gene name)|psi-mi:SPC24(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478203|imex:IM-26985-163 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138789.1|refseq:NP_001138787.1|refseq:NP_001138788.1|refseq:NP_079194.3|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-68877|reactome:R-HSA-9648025|rcsb pdb:5LSK|ensembl:ENSG00000149636(gene)|ensembl:ENST00000373750(transcript)|ensembl:ENST00000426836(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000939"(inner kinetochore)|go:"GO:0001650"(fibrillar center)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0051301"(cell division)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|mint:Q9H410|rcsb pdb:5LSI|rcsb pdb:5LSJ|refseq:NP_001138790.1|refseq:XP_006723939.1 refseq:NP_872319.1|ensembl:ENSG00000161888(gene)|ensembl:ENST00000592540(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|mint:Q8NBT2|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001303960.1|refseq:NP_001303962.1|refseq:XP_005259810.1|dip:DIP-35754N - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:cJ0wCtpLS+YkMj83k/SubkpHwuE9606 rogid:ANMEuzMkpwcbiSjx6OaHAK8vVcA9606 rigid:j5NH0tZdQDFYETz4NkWgpW3+fgo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H410 uniprotkb:O95229 intact:EBI-1001144|uniprotkb:E1P5U9|uniprotkb:Q5JW56|uniprotkb:Q9H8P4|ensembl:ENSP00000362855|ensembl:ENSP00000389810|uniprotkb:Q5JW55|uniprotkb:B4DWT2 intact:EBI-1001132|uniprotkb:Q9BWD0|ensembl:ENSP00000363055|ensembl:ENSP00000378801|uniprotkb:Q0D2I3|uniprotkb:A6NNV6 psi-mi:dsn1_human(display_long)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)|uniprotkb:C20orf172(gene name synonym)|uniprotkb:MIS13(gene name synonym) psi-mi:zwint_human(display_long)|uniprotkb:ZW10-interacting protein 1(gene name synonym)|uniprotkb:ZWINT(gene name)|psi-mi:ZWINT(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478203|imex:IM-26985-163 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138789.1|refseq:NP_001138787.1|refseq:NP_001138788.1|refseq:NP_079194.3|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-68877|reactome:R-HSA-9648025|rcsb pdb:5LSK|ensembl:ENSG00000149636(gene)|ensembl:ENST00000373750(transcript)|ensembl:ENST00000426836(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000939"(inner kinetochore)|go:"GO:0001650"(fibrillar center)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0051301"(cell division)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|mint:Q9H410|rcsb pdb:5LSI|rcsb pdb:5LSJ|refseq:NP_001138790.1|refseq:XP_006723939.1 refseq:NP_001005413.1|refseq:NP_008988.2|refseq:NP_127490.1|go:"GO:0030425"(dendrite)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051301"(cell division)|ensembl:ENSG00000122952(gene)|go:"GO:0051649"(establishment of localization in cell)|interpro:IPR029092|ensembl:ENST00000373944(transcript)|ensembl:ENST00000395405(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|mint:O95229|go:"GO:0005737"(cytoplasm)|reactome:R-HSA-141444|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|reactome:R-HSA-2467813|go:"GO:0016604"(nuclear body)|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025 - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:cJ0wCtpLS+YkMj83k/SubkpHwuE9606 rogid:iQ5h+pikwo8Yu1MnEjxLtkGg1NE9606 rigid:j5NH0tZdQDFYETz4NkWgpW3+fgo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H410 uniprotkb:Q9H081 intact:EBI-1001144|uniprotkb:E1P5U9|uniprotkb:Q5JW56|uniprotkb:Q9H8P4|ensembl:ENSP00000362855|ensembl:ENSP00000389810|uniprotkb:Q5JW55|uniprotkb:B4DWT2 intact:EBI-1001205|uniprotkb:Q96N24|ensembl:ENSP00000370557|ensembl:ENSP00000461252|ensembl:ENSP00000484532 psi-mi:dsn1_human(display_long)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)|uniprotkb:C20orf172(gene name synonym)|uniprotkb:MIS13(gene name synonym) psi-mi:mis12_human(display_long)|uniprotkb:MIS12(gene name)|psi-mi:MIS12(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478203|imex:IM-26985-163 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138789.1|refseq:NP_001138787.1|refseq:NP_001138788.1|refseq:NP_079194.3|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-68877|reactome:R-HSA-9648025|rcsb pdb:5LSK|ensembl:ENSG00000149636(gene)|ensembl:ENST00000373750(transcript)|ensembl:ENST00000426836(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000939"(inner kinetochore)|go:"GO:0001650"(fibrillar center)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0051301"(cell division)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|mint:Q9H410|rcsb pdb:5LSI|rcsb pdb:5LSJ|refseq:NP_001138790.1|refseq:XP_006723939.1 refseq:NP_001245146.1|refseq:NP_001245147.1|refseq:NP_001245148.1|refseq:NP_001245149.1|refseq:XP_016880522.1|refseq:XP_016880523.1|refseq:XP_016880524.1|refseq:NP_076944.1|ensembl:ENSG00000167842(gene)|ensembl:ENST00000381165(transcript)|ensembl:ENST00000573759(transcript)|ensembl:ENST00000611091(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR008685(Mis12)|mint:Q9H081|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-5663220|refseq:XP_005256854.1 - - comment:"author score: 180" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:cJ0wCtpLS+YkMj83k/SubkpHwuE9606 rogid:1qNMwDq3AYOWnRnPa2u3yt7O4109606 rigid:j5NH0tZdQDFYETz4NkWgpW3+fgo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H410 uniprotkb:Q9UJV8 intact:EBI-1001144|uniprotkb:E1P5U9|uniprotkb:Q5JW56|uniprotkb:Q9H8P4|ensembl:ENSP00000362855|ensembl:ENSP00000389810|uniprotkb:Q5JW55|uniprotkb:B4DWT2 intact:EBI-25478180|ensembl:ENSP00000418721|ensembl:ENSP00000466881|uniprotkb:Q8TE64 psi-mi:dsn1_human(display_long)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)|uniprotkb:C20orf172(gene name synonym)|uniprotkb:MIS13(gene name synonym) psi-mi:purg_human(display_long)|uniprotkb:PURG(gene name)|psi-mi:PURG(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478203|imex:IM-26985-163 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138789.1|refseq:NP_001138787.1|refseq:NP_001138788.1|refseq:NP_079194.3|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-68877|reactome:R-HSA-9648025|rcsb pdb:5LSK|ensembl:ENSG00000149636(gene)|ensembl:ENST00000373750(transcript)|ensembl:ENST00000426836(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000939"(inner kinetochore)|go:"GO:0001650"(fibrillar center)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0051301"(cell division)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|mint:Q9H410|rcsb pdb:5LSI|rcsb pdb:5LSJ|refseq:NP_001138790.1|refseq:XP_006723939.1 ensembl:ENSG00000172733(gene)|ensembl:ENST00000475541(transcript)|ensembl:ENST00000523392(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032422"(purine-rich negative regulatory element binding)|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|interpro:IPR030501|mint:Q9UJV8|refseq:NP_001015508.1|refseq:NP_001310240.1|refseq:NP_001310241.1|refseq:NP_037489.1 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:cJ0wCtpLS+YkMj83k/SubkpHwuE9606 rogid:L4p5p28XV86riOUCM/xZYzXXtlA9606 rigid:j5NH0tZdQDFYETz4NkWgpW3+fgo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H410 uniprotkb:Q09028 intact:EBI-1001144|uniprotkb:E1P5U9|uniprotkb:Q5JW56|uniprotkb:Q9H8P4|ensembl:ENSP00000362855|ensembl:ENSP00000389810|uniprotkb:Q5JW55|uniprotkb:B4DWT2 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 psi-mi:dsn1_human(display_long)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)|uniprotkb:C20orf172(gene name synonym)|uniprotkb:MIS13(gene name synonym) psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478203|imex:IM-26985-163 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138789.1|refseq:NP_001138787.1|refseq:NP_001138788.1|refseq:NP_079194.3|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-68877|reactome:R-HSA-9648025|rcsb pdb:5LSK|ensembl:ENSG00000149636(gene)|ensembl:ENST00000373750(transcript)|ensembl:ENST00000426836(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000939"(inner kinetochore)|go:"GO:0001650"(fibrillar center)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0051301"(cell division)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|mint:Q9H410|rcsb pdb:5LSI|rcsb pdb:5LSJ|refseq:NP_001138790.1|refseq:XP_006723939.1 ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:cJ0wCtpLS+YkMj83k/SubkpHwuE9606 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rigid:j5NH0tZdQDFYETz4NkWgpW3+fgo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H410 uniprotkb:P58557 intact:EBI-1001144|uniprotkb:E1P5U9|uniprotkb:Q5JW56|uniprotkb:Q9H8P4|ensembl:ENSP00000362855|ensembl:ENSP00000389810|uniprotkb:Q5JW55|uniprotkb:B4DWT2 intact:EBI-2114647|uniprotkb:D3DSN2|uniprotkb:B7WPA9|uniprotkb:B7WPF7|ensembl:ENSP00000329614|ensembl:ENSP00000380805|ensembl:ENSP00000380813 psi-mi:dsn1_human(display_long)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)|uniprotkb:C20orf172(gene name synonym)|uniprotkb:MIS13(gene name synonym) psi-mi:ybey_human(display_long)|uniprotkb:YBEY(gene name)|psi-mi:YBEY(display_short)|uniprotkb:C21orf57(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478203|imex:IM-26985-163 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138789.1|refseq:NP_001138787.1|refseq:NP_001138788.1|refseq:NP_079194.3|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-68877|reactome:R-HSA-9648025|rcsb pdb:5LSK|ensembl:ENSG00000149636(gene)|ensembl:ENST00000373750(transcript)|ensembl:ENST00000426836(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000939"(inner kinetochore)|go:"GO:0001650"(fibrillar center)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0051301"(cell division)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|mint:Q9H410|rcsb pdb:5LSI|rcsb pdb:5LSJ|refseq:NP_001138790.1|refseq:XP_006723939.1 refseq:NP_478061.1|refseq:NP_001300951.1|refseq:NP_001300952.1|refseq:NP_001300953.1|refseq:NP_001300954.1|refseq:NP_001300955.1|ensembl:ENSG00000182362(gene)|ensembl:ENST00000329319(transcript)|ensembl:ENST00000397691(transcript)|ensembl:ENST00000397701(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0006364"(rRNA processing)|go:"GO:0046872"(metal ion binding)|interpro:IPR002036(Protein of unknown function UPF0054)|interpro:IPR020549|interpro:IPR023091|mint:P58557 - - comment:"author score: 33" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:cJ0wCtpLS+YkMj83k/SubkpHwuE9606 rogid:VOjeUF0iThxy1T2ywZGHB8ILorc9606 rigid:j5NH0tZdQDFYETz4NkWgpW3+fgo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H410 uniprotkb:Q13185 intact:EBI-1001144|uniprotkb:E1P5U9|uniprotkb:Q5JW56|uniprotkb:Q9H8P4|ensembl:ENSP00000362855|ensembl:ENSP00000389810|uniprotkb:Q5JW55|uniprotkb:B4DWT2 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 psi-mi:dsn1_human(display_long)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)|uniprotkb:C20orf172(gene name synonym)|uniprotkb:MIS13(gene name synonym) psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478203|imex:IM-26985-163 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138789.1|refseq:NP_001138787.1|refseq:NP_001138788.1|refseq:NP_079194.3|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-68877|reactome:R-HSA-9648025|rcsb pdb:5LSK|ensembl:ENSG00000149636(gene)|ensembl:ENST00000373750(transcript)|ensembl:ENST00000426836(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000939"(inner kinetochore)|go:"GO:0001650"(fibrillar center)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0051301"(cell division)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|mint:Q9H410|rcsb pdb:5LSI|rcsb pdb:5LSJ|refseq:NP_001138790.1|refseq:XP_006723939.1 go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N - - comment:"author score: 73" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:cJ0wCtpLS+YkMj83k/SubkpHwuE9606 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rigid:j5NH0tZdQDFYETz4NkWgpW3+fgo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H410 uniprotkb:P45973 intact:EBI-1001144|uniprotkb:E1P5U9|uniprotkb:Q5JW56|uniprotkb:Q9H8P4|ensembl:ENSP00000362855|ensembl:ENSP00000389810|uniprotkb:Q5JW55|uniprotkb:B4DWT2 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 psi-mi:dsn1_human(display_long)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)|uniprotkb:C20orf172(gene name synonym)|uniprotkb:MIS13(gene name synonym) psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478203|imex:IM-26985-163 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138789.1|refseq:NP_001138787.1|refseq:NP_001138788.1|refseq:NP_079194.3|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-68877|reactome:R-HSA-9648025|rcsb pdb:5LSK|ensembl:ENSG00000149636(gene)|ensembl:ENST00000373750(transcript)|ensembl:ENST00000426836(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000939"(inner kinetochore)|go:"GO:0001650"(fibrillar center)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0051301"(cell division)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|mint:Q9H410|rcsb pdb:5LSI|rcsb pdb:5LSJ|refseq:NP_001138790.1|refseq:XP_006723939.1 go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N - - comment:"author score: 90" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:cJ0wCtpLS+YkMj83k/SubkpHwuE9606 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rigid:j5NH0tZdQDFYETz4NkWgpW3+fgo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H410 uniprotkb:Q96IY1 intact:EBI-1001144|uniprotkb:E1P5U9|uniprotkb:Q5JW56|uniprotkb:Q9H8P4|ensembl:ENSP00000362855|ensembl:ENSP00000389810|uniprotkb:Q5JW55|uniprotkb:B4DWT2 intact:EBI-2554690|uniprotkb:Q9H2M5|uniprotkb:Q5SY75|uniprotkb:Q9Y415|uniprotkb:Q9NRN8|ensembl:ENSP00000355944|uniprotkb:E7ETD5 psi-mi:dsn1_human(display_long)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)|uniprotkb:C20orf172(gene name synonym)|uniprotkb:MIS13(gene name synonym) psi-mi:nsl1_human(display_long)|uniprotkb:C1orf48(gene name synonym)|uniprotkb:DC8(orf name)|uniprotkb:DC31(orf name)|uniprotkb:MIS14(orf name)|uniprotkb:NSL1(gene name)|psi-mi:NSL1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478203|imex:IM-26985-163 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138789.1|refseq:NP_001138787.1|refseq:NP_001138788.1|refseq:NP_079194.3|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-68877|reactome:R-HSA-9648025|rcsb pdb:5LSK|ensembl:ENSG00000149636(gene)|ensembl:ENST00000373750(transcript)|ensembl:ENST00000426836(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000939"(inner kinetochore)|go:"GO:0001650"(fibrillar center)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0051301"(cell division)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|mint:Q9H410|rcsb pdb:5LSI|rcsb pdb:5LSJ|refseq:NP_001138790.1|refseq:XP_006723939.1 refseq:NP_056286.3|ensembl:ENSG00000117697(gene)|ensembl:ENST00000366977(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0005829"(cytosol)|go:"GO:0016607"(nuclear speck)|go:"GO:0051301"(cell division)|interpro:IPR013950(Kinetochore Mis14)|mint:Q96IY1|rcsb pdb:4NF9|rcsb pdb:5LSI|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-2500257|reactome:R-HSA-9648025|refseq:NP_001036014.1 - - comment:"author score: 132" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:cJ0wCtpLS+YkMj83k/SubkpHwuE9606 rogid:w4K2MEHLfZvFECNhtDanXWF0LQk9606 rigid:j5NH0tZdQDFYETz4NkWgpW3+fgo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H410 uniprotkb:Q6P1K2 intact:EBI-1001144|uniprotkb:E1P5U9|uniprotkb:Q5JW56|uniprotkb:Q9H8P4|ensembl:ENSP00000362855|ensembl:ENSP00000389810|uniprotkb:Q5JW55|uniprotkb:B4DWT2 intact:EBI-713832|uniprotkb:Q5TCJ8|uniprotkb:Q5TCJ9|uniprotkb:Q5TCK3|uniprotkb:Q69YZ9|uniprotkb:Q6PHR4|uniprotkb:Q86VJ6|uniprotkb:Q8N4T6|uniprotkb:Q9UBQ3|uniprotkb:A8K0C5|intact:EBI-2554676|uniprotkb:Q5TCK0|ensembl:ENSP00000357260|uniprotkb:Q5TCK1|uniprotkb:Q6ZVE6 psi-mi:dsn1_human(display_long)|uniprotkb:DSN1(gene name)|psi-mi:DSN1(display_short)|uniprotkb:C20orf172(gene name synonym)|uniprotkb:MIS13(gene name synonym) psi-mi:pmf1_human(display_long)|uniprotkb:PMF1(gene name)|psi-mi:PMF1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478203|imex:IM-26985-163 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138789.1|refseq:NP_001138787.1|refseq:NP_001138788.1|refseq:NP_079194.3|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-68877|reactome:R-HSA-9648025|rcsb pdb:5LSK|ensembl:ENSG00000149636(gene)|ensembl:ENST00000373750(transcript)|ensembl:ENST00000426836(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0000939"(inner kinetochore)|go:"GO:0001650"(fibrillar center)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0051301"(cell division)|interpro:IPR013218(Mtw1 kinetochore complex, DSN1)|mint:Q9H410|rcsb pdb:5LSI|rcsb pdb:5LSJ|refseq:NP_001138790.1|refseq:XP_006723939.1 ensembl:ENSG00000160783(gene)|ensembl:ENST00000368277(transcript)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0051301"(cell division)|interpro:IPR007128(Nnf1)|mint:Q6P1K2|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001186582.1|refseq:NP_001186583.1|refseq:NP_001186590.1|refseq:NP_001186592.1|refseq:NP_009152.2 - - comment:"author score: 137" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:cJ0wCtpLS+YkMj83k/SubkpHwuE9606 rogid:76xPGmFgI3Pt1gsZMb3aD4hpPWM9606 rigid:j5NH0tZdQDFYETz4NkWgpW3+fgo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P26196 uniprotkb:P11940 intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754 intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004 psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym) psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478066|imex:IM-26985-243 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606 rogid:XudTSPq2h9ckKAc48X88RVafPRU9606 rigid:GRtMglaronJmM1bwehvsw/eJqvA false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P26196 uniprotkb:Q13310 intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754 intact:EBI-372844|uniprotkb:Q6P0N3|uniprotkb:B1ANQ8|ensembl:ENSP00000361948|intact:EBI-877641|uniprotkb:Q4VC03 psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym) psi-mi:pabp4_human(display_long)|uniprotkb:PABPC4(gene name)|psi-mi:PABPC4(display_short)|uniprotkb:APP1(gene name synonym)|uniprotkb:PABP4(gene name synonym)|uniprotkb:"Inducible poly(A)-binding protein"(gene name synonym)|uniprotkb:Activated-platelet protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478066|imex:IM-26985-243 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N refseq:NP_001129126.1|refseq:NP_003810.1|ensembl:ENSG00000090621(gene)|ensembl:ENST00000372857(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006412"(translation)|go:"GO:0007596"(blood coagulation)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0061515"(myeloid cell development)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:Q13310|refseq:NP_001129125.1 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606 rogid:u1qCM3o5X7jLIa1vyqFCIH7v01w9606 rigid:GRtMglaronJmM1bwehvsw/eJqvA false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P26196 uniprotkb:Q6P2E9 intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754 intact:EBI-1006038|uniprotkb:Q13025|uniprotkb:Q13826|uniprotkb:Q6ZR12|uniprotkb:Q7Z6H7|uniprotkb:A6NGM1|uniprotkb:A8K4T4|ensembl:ENSP00000351811 psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym) psi-mi:edc4_human(display_long)|uniprotkb:Human enhancer of decapping large subunit(gene name synonym)|uniprotkb:Autoantigen Ge-1(gene name synonym)|uniprotkb:Autoantigen RCD-8(gene name synonym)|uniprotkb:EDC4(gene name)|psi-mi:EDC4(display_short)|uniprotkb:HEDLS(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478066|imex:IM-26985-243 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N ensembl:ENSG00000038358(gene)|interpro:IPR036322|mint:Q6P2E9|reactome:R-HSA-430039|ensembl:ENST00000358933(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR032401|refseq:NP_055144.3|dip:DIP-31192N - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606 rogid:V5obZo71xmJbNRv5fc+o7wNdb+Y9606 rigid:GRtMglaronJmM1bwehvsw/eJqvA false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P26196 uniprotkb:Q8ND56 intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754 intact:EBI-1384320|uniprotkb:Q76LX7|uniprotkb:Q96AR3|uniprotkb:Q96K73|uniprotkb:Q96SN5|uniprotkb:Q9UFR3|intact:EBI-2563702|uniprotkb:B4DTG6|ensembl:ENSP00000413964|ensembl:ENSP00000459843 psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym) psi-mi:ls14a_human(display_long)|uniprotkb:C19orf13(gene name synonym)|uniprotkb:FAM61A(gene name synonym)|uniprotkb:Protein SCD6 homolog(gene name synonym)|uniprotkb:Protein FAM61A(gene name synonym)|uniprotkb:Putative alpha-synuclein-binding protein(gene name synonym)|uniprotkb:LSM14A(gene name)|psi-mi:LSM14A(display_short)|uniprotkb:RAP55(gene name synonym)|uniprotkb:RAP55A(gene name synonym)|uniprotkb:RNA-associated protein 55A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478066|imex:IM-26985-243 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N refseq:NP_001107565.1|refseq:NP_056393.2|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR019050|interpro:IPR025609|interpro:IPR025761|interpro:IPR025762|interpro:IPR025768|mint:Q8ND56|rcsb pdb:6F9W|ensembl:ENSG00000257103(gene)|ensembl:ENSG00000262860(gene)|ensembl:ENST00000433627(transcript)|ensembl:ENST00000570462(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway) - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606 rogid:YW/zx4XyhcZZr3WCZIr1OVpyakA9606 rigid:GRtMglaronJmM1bwehvsw/eJqvA false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P26196 uniprotkb:A6NED2 intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754 intact:EBI-21552314|ensembl:ENSP00000377801|ensembl:ENSP00000451963|uniprotkb:B2RTP9|uniprotkb:Q29RX6 psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym) psi-mi:rccd1_human(display_long)|uniprotkb:RCCD1(gene name)|psi-mi:RCCD1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478066|imex:IM-26985-243 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N ensembl:ENSG00000166965(gene)|ensembl:ENST00000394258(transcript)|ensembl:ENST00000556618(transcript)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|mint:A6NED2|rcsb pdb:6F4R|rcsb pdb:6F4S|rcsb pdb:6F4T|refseq:NP_001017919.1|refseq:NP_291022.2 - - comment:"author score: 30" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606 rogid:pJ4TNM7dmfISs5RIVzio/hBYHp09606 rigid:GRtMglaronJmM1bwehvsw/eJqvA false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P26196 uniprotkb:Q99700 intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754 intact:EBI-697691|uniprotkb:Q6ZQZ7|uniprotkb:Q99493|uniprotkb:A6NLD4|uniprotkb:Q24JQ7|ensembl:ENSP00000446576 psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym) psi-mi:atx2_human(display_long)|uniprotkb:Spinocerebellar ataxia type 2 protein(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 13 protein(gene name synonym)|uniprotkb:SCA2(gene name synonym)|uniprotkb:TNRC13(gene name synonym)|uniprotkb:ATXN2(gene name)|psi-mi:ATXN2(display_short)|uniprotkb:ATX2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478066|imex:IM-26985-243 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N refseq:NP_002964.3|refseq:NP_001297052.1|ensembl:ENSG00000204842(gene)|ensembl:ENST00000550104(transcript)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0003723"(RNA binding)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006417"(regulation of translation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050658"(RNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR009604(Ataxin-2, N-terminal)|interpro:IPR009818(Ataxin-2, C-terminal)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR025852|interpro:IPR033093|mint:Q99700|rcsb pdb:3KTR|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000535949|ensembl:ENSP00000439338|ensembl:ENSP00000446576|ensembl:ENST00000616825|ensembl:ENSP00000481448|dip:DIP-33372N - - comment:"author score: 41" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606 rogid:HGRv/9J/X3JIj2KmcHviwd2ygPw9606 rigid:GRtMglaronJmM1bwehvsw/eJqvA false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P26196 uniprotkb:Q7Z417 intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754 intact:EBI-1210753|intact:EBI-10172018|uniprotkb:A1L3A7|uniprotkb:Q9P2M5|uniprotkb:A1L3A6|ensembl:ENSP00000225388 psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym) psi-mi:nufp2_human(display_long)|uniprotkb:NUFIP2(gene name)|psi-mi:NUFIP2(display_short)|uniprotkb:KIAA1321(gene name synonym)|uniprotkb:PIG1(orf name)|uniprotkb:FMRP-interacting protein 2(gene name synonym)|uniprotkb:82 kDa FMRP-interacting protein(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 1 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478066|imex:IM-26985-243 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N refseq:NP_065823.1|dip:DIP-29023N|ensembl:ENSG00000108256(gene)|ensembl:ENST00000225388(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR032747|mint:Q7Z417 - - comment:"author score: 41" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606 rogid:zdbkRisveP+8g70umfbEPHTnAgk9606 rigid:GRtMglaronJmM1bwehvsw/eJqvA false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P26196 uniprotkb:Q8WWM7 intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754 intact:EBI-948363|ensembl:ENSP00000338718|uniprotkb:O95135|uniprotkb:Q6NVJ8|uniprotkb:Q6PJW6|uniprotkb:Q8IU61|uniprotkb:Q8IU95|uniprotkb:Q8WWM3|uniprotkb:Q8WWM4|uniprotkb:Q8WWM5|uniprotkb:Q8WWM6|uniprotkb:Q99703|uniprotkb:B9EGM2|uniprotkb:E9PAR9|uniprotkb:A8K1R6|uniprotkb:Q63ZY4 psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym) psi-mi:atx2l_human(display_long)|uniprotkb:Ataxin-2 domain protein(gene name synonym)|uniprotkb:Ataxin-2-related protein(gene name synonym)|uniprotkb:ATXN2L(gene name)|psi-mi:ATXN2L(display_short)|uniprotkb:A2D(gene name synonym)|uniprotkb:A2LG(gene name synonym)|uniprotkb:A2LP(gene name synonym)|uniprotkb:A2RP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478066|imex:IM-26985-243 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N ensembl:ENSG00000168488(gene)|ensembl:ENST00000336783(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045296"(cadherin binding)|interpro:IPR009604(Ataxin-2, N-terminal)|interpro:IPR009818(Ataxin-2, C-terminal)|interpro:IPR025852|mint:Q8WWM7|refseq:NP_009176.2|refseq:NP_663760.1|refseq:NP_680780.1|refseq:NP_680781.1|refseq:XP_005255123.1|refseq:NP_059867.3|refseq:NP_680782.1 - - comment:"author score: 58" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606 rogid:t7lrS10IM/5pt+rrbqBRowZ6b+09606 rigid:GRtMglaronJmM1bwehvsw/eJqvA false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P26196 uniprotkb:Q3MHD2 intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754 intact:EBI-725133|uniprotkb:Q86YB1|uniprotkb:Q96NL5|ensembl:ENSP00000293406|ensembl:ENSP00000466718 psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym) psi-mi:lsm12_human(display_long)|uniprotkb:LSM12(gene name)|psi-mi:LSM12(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478066|imex:IM-26985-243 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N refseq:NP_689557.1|ensembl:ENSG00000161654(gene)|ensembl:ENST00000293406(transcript)|ensembl:ENST00000591247(transcript)|interpro:IPR019181|interpro:IPR039683|mint:Q3MHD2 - - comment:"author score: 67" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606 rogid:SY9HUXXLZyXhttFb+AXkMh0QOek9606 rigid:GRtMglaronJmM1bwehvsw/eJqvA false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P26196 uniprotkb:Q8IZD4 intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754 intact:EBI-521595|ensembl:ENSP00000280665|ensembl:ENSP00000494635|uniprotkb:Q86XH9|uniprotkb:Q96BP8|uniprotkb:Q96MZ8|uniprotkb:B4DRD1 psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym) psi-mi:dcp1b_human(display_long)|uniprotkb:DCP1B(gene name)|psi-mi:DCP1B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478066|imex:IM-26985-243 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N ensembl:ENSG00000151065(gene)|ensembl:ENSG00000284850(gene)|ensembl:ENST00000280665(transcript)|ensembl:ENST00000647122(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q8IZD4|reactome:R-HSA-430039|refseq:NP_689853.3|dip:DIP-31289N|refseq:XP_011519229.1 - - comment:"author score: 78" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606 rogid:fb+/Ls2ohlQHbAa9FZWzpIAH3sU9606 rigid:GRtMglaronJmM1bwehvsw/eJqvA false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P26196 uniprotkb:Q9NPI6 intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754 intact:EBI-374238|ensembl:ENSP00000476386|uniprotkb:B4DHN9|uniprotkb:U3KQM8 psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym) psi-mi:dcp1a_human(display_long)|uniprotkb:DCP1A(gene name)|psi-mi:DCP1A(display_short)|uniprotkb:Transcription factor SMIF(gene name synonym)|uniprotkb:Smad4-interacting transcriptional co-activator(gene name synonym)|uniprotkb:SMIF(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478066|imex:IM-26985-243 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N ensembl:ENSG00000272886(gene)|ensembl:ENST00000610213(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000290"(deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019894"(kinesin binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|interpro:IPR010334(Dcp1-like decapping)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR031953|mint:Q9NPI6|rcsb pdb:2WX3|rcsb pdb:4B6H|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-975957|refseq:NP_060873.4|refseq:NP_001277133.1|refseq:NP_001277136.1|refseq:NP_001277134.1|refseq:NP_001277135.1|dip:DIP-31292N - - comment:"author score: 152" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606 rogid:KIg2pPmAEIiig2SXAJNziN91oCY9606 rigid:GRtMglaronJmM1bwehvsw/eJqvA false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P26196 uniprotkb:Q96F86 intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754 intact:EBI-997311|uniprotkb:Q9H797|uniprotkb:B3KPH0|uniprotkb:D3DW61|ensembl:ENSP00000497737|ensembl:ENSP00000320503|ensembl:ENSP00000401343|ensembl:ENSP00000455580 psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym) psi-mi:edc3_human(display_long)|uniprotkb:YjeF domain-containing protein 1(gene name synonym)|uniprotkb:LSM16 homolog(gene name synonym)|uniprotkb:EDC3(gene name)|psi-mi:EDC3(display_short)|uniprotkb:PP844(orf name)|uniprotkb:LSM16(gene name synonym)|uniprotkb:YJDC(gene name synonym)|uniprotkb:YJEFN2(gene name synonym)|uniprotkb:YjeF N-terminal domain-containing protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478066|imex:IM-26985-243 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N refseq:NP_001135915.1|refseq:NP_001135916.1|refseq:NP_079359.2|ensembl:ENST00000315127(transcript)|ensembl:ENST00000426797(transcript)|ensembl:ENST00000568176(transcript)|ensembl:ENST00000647659(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003729"(mRNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0031087"(deadenylation-independent decapping of nuclear-transcribed mRNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:1990174"(phosphodiesterase decapping endonuclease activity)|interpro:IPR004443(YjeF-related protein, N-terminal)|interpro:IPR019050|interpro:IPR025609|interpro:IPR025762|interpro:IPR034107|interpro:IPR036652|mint:Q96F86|rcsb pdb:2VC8|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:3D3J|rcsb pdb:3D3K|rcsb pdb:6S8S|reactome:R-HSA-430039|ensembl:ENSG00000179151(gene)|dip:DIP-35516N - - comment:"author score: 165" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606 rogid:AFS114ghTqHNid3eOFB7iQsfwAg9606 rigid:GRtMglaronJmM1bwehvsw/eJqvA false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96KQ7 uniprotkb:Q7Z3K3 intact:EBI-744366|uniprotkb:B0UZY2|uniprotkb:Q14349|uniprotkb:Q6PK06|uniprotkb:Q96MH5|uniprotkb:Q96QD0|uniprotkb:Q9UQL8|uniprotkb:Q9Y331|uniprotkb:Q5JQ92|uniprotkb:Q5JP83|uniprotkb:Q5JQA1|uniprotkb:Q5JQG3|ensembl:ENSP00000364687|ensembl:ENSP00000372864|ensembl:ENSP00000392305|ensembl:ENSP00000396119|ensembl:ENSP00000406110|ensembl:ENSP00000416957 intact:EBI-1389308|uniprotkb:O75049|uniprotkb:Q5SZS2|uniprotkb:Q5SZS3|uniprotkb:Q5SZS4|uniprotkb:Q8TDZ7|uniprotkb:Q9Y4X7|uniprotkb:Q3LIC4|uniprotkb:Q5SZS1|intact:EBI-2560449|intact:EBI-11742841|uniprotkb:B4DTP8|uniprotkb:B4DYL9|uniprotkb:B7ZBY5|uniprotkb:E9PM80|intact:EBI-14072025|intact:EBI-17205119|intact:EBI-22321456|intact:EBI-12748249|intact:EBI-16429759|ensembl:ENSP00000271715 psi-mi:ehmt2_human(display_long)|uniprotkb:KMT1C(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 3(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 8(gene name synonym)|uniprotkb:Protein G9a(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1C(gene name synonym)|uniprotkb:EHMT2(gene name)|psi-mi:EHMT2(display_short)|uniprotkb:BAT8(gene name synonym)|uniprotkb:G9A(gene name synonym)|uniprotkb:NG36(gene name synonym)|uniprotkb:C6orf30(gene name synonym) psi-mi:pogz_human(display_long)|uniprotkb:POGZ(gene name)|psi-mi:POGZ(display_short)|uniprotkb:KIAA0461(gene name synonym)|uniprotkb:Nbla00003(orf name)|uniprotkb:SUHW5(gene name synonym)|uniprotkb:ZNF280E(gene name synonym)|uniprotkb:ZNF635(gene name synonym)|uniprotkb:Suppressor of hairy wing homolog 5(gene name synonym)|uniprotkb:Zinc finger protein 280E(gene name synonym)|uniprotkb:Zinc finger protein 635(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478242|imex:IM-26985-85 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006700.3|refseq:NP_079532.5|interpro:IPR043550|mint:Q96KQ7|rcsb pdb:2O8J|rcsb pdb:3DM1|rcsb pdb:3K5K|rcsb pdb:3RJW|rcsb pdb:4NVQ|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5TTF|rcsb pdb:5TUY|rcsb pdb:5V9I|rcsb pdb:5VSC|rcsb pdb:5VSE|rcsb pdb:6MM1|rcsb pdb:7BTV|rcsb pdb:7BUC|rcsb pdb:7DCF|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-6804760|reactome:R-HSA-73762|reactome:R-HSA-8853884|reactome:R-HSA-8953750|ensembl:ENSG00000204371(gene)|ensembl:ENSG00000206376(gene)|ensembl:ENSG00000227333(gene)|ensembl:ENSG00000232045(gene)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035265"(organ growth)|go:"GO:0035690"|go:"GO:0036166"(phenotypic switching)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045471"(response to ethanol)|ensembl:ENSG00000236759(gene)|ensembl:ENSG00000238134(gene)|ensembl:ENST00000375537(transcript)|ensembl:ENST00000383373(transcript)|ensembl:ENST00000420336(transcript)|ensembl:ENST00000421926(transcript)|ensembl:ENST00000429506(transcript)|ensembl:ENST00000450075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006306"(DNA methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007286"(spermatid development)|go:"GO:0007616"(long-term memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009566"(fertilization)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038034|refseq:NP_001305762.1|refseq:NP_001276342.1|dip:DIP-34461N refseq:NP_001181866.1|refseq:NP_001181867.1|refseq:NP_055915.2|refseq:NP_665739.3|refseq:NP_997054.1|refseq:XP_016856234.1|refseq:XP_016856235.1|refseq:XP_016856237.1|refseq:XP_016856238.1|refseq:XP_005245056.1|refseq:XP_005245057.1|refseq:XP_005245058.1|refseq:XP_005245062.1|refseq:XP_005245063.1|dip:DIP-38044N|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|ensembl:ENSG00000143442(gene)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|ensembl:ENST00000271715(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR004875(CENP-B protein)|interpro:IPR006600(Centromere protein B, helix-turn-helix)|interpro:IPR009057(Homeodomain-like)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q7Z3K3|rcsb pdb:2E72|rcsb pdb:2N3A|rcsb pdb:6EMP - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dblr0h0KBVa6kvaDHhnynRuHE6E9606 rogid:sCOIY8KsHRQtfcoSA9Tixl9yIsc9606 rigid:N2K6bjx/ymg9ftd6qkp/M7Qo5ZM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96KQ7 uniprotkb:P68363 intact:EBI-744366|uniprotkb:B0UZY2|uniprotkb:Q14349|uniprotkb:Q6PK06|uniprotkb:Q96MH5|uniprotkb:Q96QD0|uniprotkb:Q9UQL8|uniprotkb:Q9Y331|uniprotkb:Q5JQ92|uniprotkb:Q5JP83|uniprotkb:Q5JQA1|uniprotkb:Q5JQG3|ensembl:ENSP00000364687|ensembl:ENSP00000372864|ensembl:ENSP00000392305|ensembl:ENSP00000396119|ensembl:ENSP00000406110|ensembl:ENSP00000416957 intact:EBI-487083|intact:EBI-1384226|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:Q27I68|ensembl:ENSP00000336799|uniprotkb:Q8WU19 psi-mi:ehmt2_human(display_long)|uniprotkb:KMT1C(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 3(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 8(gene name synonym)|uniprotkb:Protein G9a(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1C(gene name synonym)|uniprotkb:EHMT2(gene name)|psi-mi:EHMT2(display_short)|uniprotkb:BAT8(gene name synonym)|uniprotkb:G9A(gene name synonym)|uniprotkb:NG36(gene name synonym)|uniprotkb:C6orf30(gene name synonym) psi-mi:tba1b_human(display_long)|uniprotkb:TUBA1B(gene name)|psi-mi:TUBA1B(display_short)|uniprotkb:Tubulin alpha-ubiquitous chain(gene name synonym)|uniprotkb:Alpha-tubulin ubiquitous(gene name synonym)|uniprotkb:Tubulin K-alpha-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478242|imex:IM-26985-85 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006700.3|refseq:NP_079532.5|interpro:IPR043550|mint:Q96KQ7|rcsb pdb:2O8J|rcsb pdb:3DM1|rcsb pdb:3K5K|rcsb pdb:3RJW|rcsb pdb:4NVQ|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5TTF|rcsb pdb:5TUY|rcsb pdb:5V9I|rcsb pdb:5VSC|rcsb pdb:5VSE|rcsb pdb:6MM1|rcsb pdb:7BTV|rcsb pdb:7BUC|rcsb pdb:7DCF|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-6804760|reactome:R-HSA-73762|reactome:R-HSA-8853884|reactome:R-HSA-8953750|ensembl:ENSG00000204371(gene)|ensembl:ENSG00000206376(gene)|ensembl:ENSG00000227333(gene)|ensembl:ENSG00000232045(gene)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035265"(organ growth)|go:"GO:0035690"|go:"GO:0036166"(phenotypic switching)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045471"(response to ethanol)|ensembl:ENSG00000236759(gene)|ensembl:ENSG00000238134(gene)|ensembl:ENST00000375537(transcript)|ensembl:ENST00000383373(transcript)|ensembl:ENST00000420336(transcript)|ensembl:ENST00000421926(transcript)|ensembl:ENST00000429506(transcript)|ensembl:ENST00000450075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006306"(DNA methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007286"(spermatid development)|go:"GO:0007616"(long-term memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009566"(fertilization)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038034|refseq:NP_001305762.1|refseq:NP_001276342.1|dip:DIP-34461N refseq:NP_006073.2|ensembl:ENSG00000123416(gene)|ensembl:ENST00000336023(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-983189|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|go:"GO:0045121"(membrane raft)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68363|rcsb pdb:2E4H|rcsb pdb:5IJ0|rcsb pdb:5IJ9|rcsb pdb:5N5N|rcsb pdb:6E7B|rcsb pdb:6E7C|rcsb pdb:6I2I|go:"GO:0051301"(cell division)|rcsb pdb:6J4V|rcsb pdb:6J8O|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|rcsb pdb:6S8L|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9013407|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-2132295|reactome:R-HSA-9668328 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dblr0h0KBVa6kvaDHhnynRuHE6E9606 rogid:D4YpuLCXl/S+53qV7P7sF81aARY9606 rigid:N2K6bjx/ymg9ftd6qkp/M7Qo5ZM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96KQ7 uniprotkb:Q13185 intact:EBI-744366|uniprotkb:B0UZY2|uniprotkb:Q14349|uniprotkb:Q6PK06|uniprotkb:Q96MH5|uniprotkb:Q96QD0|uniprotkb:Q9UQL8|uniprotkb:Q9Y331|uniprotkb:Q5JQ92|uniprotkb:Q5JP83|uniprotkb:Q5JQA1|uniprotkb:Q5JQG3|ensembl:ENSP00000364687|ensembl:ENSP00000372864|ensembl:ENSP00000392305|ensembl:ENSP00000396119|ensembl:ENSP00000406110|ensembl:ENSP00000416957 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 psi-mi:ehmt2_human(display_long)|uniprotkb:KMT1C(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 3(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 8(gene name synonym)|uniprotkb:Protein G9a(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1C(gene name synonym)|uniprotkb:EHMT2(gene name)|psi-mi:EHMT2(display_short)|uniprotkb:BAT8(gene name synonym)|uniprotkb:G9A(gene name synonym)|uniprotkb:NG36(gene name synonym)|uniprotkb:C6orf30(gene name synonym) psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478242|imex:IM-26985-85 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006700.3|refseq:NP_079532.5|interpro:IPR043550|mint:Q96KQ7|rcsb pdb:2O8J|rcsb pdb:3DM1|rcsb pdb:3K5K|rcsb pdb:3RJW|rcsb pdb:4NVQ|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5TTF|rcsb pdb:5TUY|rcsb pdb:5V9I|rcsb pdb:5VSC|rcsb pdb:5VSE|rcsb pdb:6MM1|rcsb pdb:7BTV|rcsb pdb:7BUC|rcsb pdb:7DCF|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-6804760|reactome:R-HSA-73762|reactome:R-HSA-8853884|reactome:R-HSA-8953750|ensembl:ENSG00000204371(gene)|ensembl:ENSG00000206376(gene)|ensembl:ENSG00000227333(gene)|ensembl:ENSG00000232045(gene)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035265"(organ growth)|go:"GO:0035690"|go:"GO:0036166"(phenotypic switching)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045471"(response to ethanol)|ensembl:ENSG00000236759(gene)|ensembl:ENSG00000238134(gene)|ensembl:ENST00000375537(transcript)|ensembl:ENST00000383373(transcript)|ensembl:ENST00000420336(transcript)|ensembl:ENST00000421926(transcript)|ensembl:ENST00000429506(transcript)|ensembl:ENST00000450075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006306"(DNA methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007286"(spermatid development)|go:"GO:0007616"(long-term memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009566"(fertilization)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038034|refseq:NP_001305762.1|refseq:NP_001276342.1|dip:DIP-34461N go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dblr0h0KBVa6kvaDHhnynRuHE6E9606 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rigid:N2K6bjx/ymg9ftd6qkp/M7Qo5ZM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96KQ7 uniprotkb:P02810 intact:EBI-744366|uniprotkb:B0UZY2|uniprotkb:Q14349|uniprotkb:Q6PK06|uniprotkb:Q96MH5|uniprotkb:Q96QD0|uniprotkb:Q9UQL8|uniprotkb:Q9Y331|uniprotkb:Q5JQ92|uniprotkb:Q5JP83|uniprotkb:Q5JQA1|uniprotkb:Q5JQG3|ensembl:ENSP00000364687|ensembl:ENSP00000372864|ensembl:ENSP00000392305|ensembl:ENSP00000396119|ensembl:ENSP00000406110|ensembl:ENSP00000416957 intact:EBI-738601|uniprotkb:Q4VBP2|uniprotkb:Q53XA2|uniprotkb:Q6P2F6|uniprotkb:A2VCM0|uniprotkb:A3KN66|uniprotkb:A5D902|uniprotkb:B2RMW2|ensembl:ENSP00000371271|ensembl:ENSP00000379682|ensembl:ENSP00000458690|ensembl:ENSP00000461041|ensembl:ENSP00000481810|ensembl:ENSP00000483458 psi-mi:ehmt2_human(display_long)|uniprotkb:KMT1C(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 3(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 8(gene name synonym)|uniprotkb:Protein G9a(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1C(gene name synonym)|uniprotkb:EHMT2(gene name)|psi-mi:EHMT2(display_short)|uniprotkb:BAT8(gene name synonym)|uniprotkb:G9A(gene name synonym)|uniprotkb:NG36(gene name synonym)|uniprotkb:C6orf30(gene name synonym) psi-mi:prpc_human(display_long)|uniprotkb:PRH1(gene name)|psi-mi:PRH1(display_short)|uniprotkb:PRH2(gene name)|psi-mi:PRH2(display_short)|uniprotkb:PRP-1/PRP-2(gene name synonym)|uniprotkb:Parotid proline-rich protein 1/2(gene name synonym)|uniprotkb:Pr1/Pr2(gene name synonym)|uniprotkb:Protein C(gene name synonym)|uniprotkb:Parotid acidic protein(gene name synonym)|uniprotkb:Parotid isoelectric focusing variant protein(gene name synonym)|uniprotkb:Parotid double-band protein(gene name synonym)|uniprotkb:Db-s(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478242|imex:IM-26985-85 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006700.3|refseq:NP_079532.5|interpro:IPR043550|mint:Q96KQ7|rcsb pdb:2O8J|rcsb pdb:3DM1|rcsb pdb:3K5K|rcsb pdb:3RJW|rcsb pdb:4NVQ|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5TTF|rcsb pdb:5TUY|rcsb pdb:5V9I|rcsb pdb:5VSC|rcsb pdb:5VSE|rcsb pdb:6MM1|rcsb pdb:7BTV|rcsb pdb:7BUC|rcsb pdb:7DCF|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-6804760|reactome:R-HSA-73762|reactome:R-HSA-8853884|reactome:R-HSA-8953750|ensembl:ENSG00000204371(gene)|ensembl:ENSG00000206376(gene)|ensembl:ENSG00000227333(gene)|ensembl:ENSG00000232045(gene)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035265"(organ growth)|go:"GO:0035690"|go:"GO:0036166"(phenotypic switching)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045471"(response to ethanol)|ensembl:ENSG00000236759(gene)|ensembl:ENSG00000238134(gene)|ensembl:ENST00000375537(transcript)|ensembl:ENST00000383373(transcript)|ensembl:ENST00000420336(transcript)|ensembl:ENST00000421926(transcript)|ensembl:ENST00000429506(transcript)|ensembl:ENST00000450075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006306"(DNA methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007286"(spermatid development)|go:"GO:0007616"(long-term memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009566"(fertilization)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038034|refseq:NP_001305762.1|refseq:NP_001276342.1|dip:DIP-34461N refseq:NP_001278243.1|refseq:NP_001278244.1|refseq:NP_001103683.1|ensembl:ENSG00000134551(gene)|ensembl:ENSG00000272803(gene)|ensembl:ENSG00000275679(gene)|ensembl:ENST00000381847(transcript)|ensembl:ENST00000396400(transcript)|ensembl:ENST00000572141(transcript)|ensembl:ENST00000575657(transcript)|ensembl:ENST00000622570(transcript)|ensembl:ENST00000622848(transcript)|go:"GO:0005615"(extracellular space)|interpro:IPR026086|mint:P02810 - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dblr0h0KBVa6kvaDHhnynRuHE6E9606 rogid:u2v00Il3agr2ZJIHSmrqcRa31DI9606 rigid:N2K6bjx/ymg9ftd6qkp/M7Qo5ZM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96KQ7 uniprotkb:P54296 intact:EBI-744366|uniprotkb:B0UZY2|uniprotkb:Q14349|uniprotkb:Q6PK06|uniprotkb:Q96MH5|uniprotkb:Q96QD0|uniprotkb:Q9UQL8|uniprotkb:Q9Y331|uniprotkb:Q5JQ92|uniprotkb:Q5JP83|uniprotkb:Q5JQA1|uniprotkb:Q5JQG3|ensembl:ENSP00000364687|ensembl:ENSP00000372864|ensembl:ENSP00000392305|ensembl:ENSP00000396119|ensembl:ENSP00000406110|ensembl:ENSP00000416957 intact:EBI-5357134|uniprotkb:Q7Z3Y2|ensembl:ENSP00000262113|ensembl:ENSP00000478322 psi-mi:ehmt2_human(display_long)|uniprotkb:KMT1C(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 3(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 8(gene name synonym)|uniprotkb:Protein G9a(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1C(gene name synonym)|uniprotkb:EHMT2(gene name)|psi-mi:EHMT2(display_short)|uniprotkb:BAT8(gene name synonym)|uniprotkb:G9A(gene name synonym)|uniprotkb:NG36(gene name synonym)|uniprotkb:C6orf30(gene name synonym) psi-mi:myom2_human(display_long)|uniprotkb:MYOM2(gene name)|psi-mi:MYOM2(display_short)|uniprotkb:165 kDa connectin-associated protein(gene name synonym)|uniprotkb:165 kDa titin-associated protein(gene name synonym)|uniprotkb:M-protein(gene name synonym)|uniprotkb:Myomesin family member 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478242|imex:IM-26985-85 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006700.3|refseq:NP_079532.5|interpro:IPR043550|mint:Q96KQ7|rcsb pdb:2O8J|rcsb pdb:3DM1|rcsb pdb:3K5K|rcsb pdb:3RJW|rcsb pdb:4NVQ|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5TTF|rcsb pdb:5TUY|rcsb pdb:5V9I|rcsb pdb:5VSC|rcsb pdb:5VSE|rcsb pdb:6MM1|rcsb pdb:7BTV|rcsb pdb:7BUC|rcsb pdb:7DCF|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-6804760|reactome:R-HSA-73762|reactome:R-HSA-8853884|reactome:R-HSA-8953750|ensembl:ENSG00000204371(gene)|ensembl:ENSG00000206376(gene)|ensembl:ENSG00000227333(gene)|ensembl:ENSG00000232045(gene)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035265"(organ growth)|go:"GO:0035690"|go:"GO:0036166"(phenotypic switching)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045471"(response to ethanol)|ensembl:ENSG00000236759(gene)|ensembl:ENSG00000238134(gene)|ensembl:ENST00000375537(transcript)|ensembl:ENST00000383373(transcript)|ensembl:ENST00000420336(transcript)|ensembl:ENST00000421926(transcript)|ensembl:ENST00000429506(transcript)|ensembl:ENST00000450075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006306"(DNA methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007286"(spermatid development)|go:"GO:0007616"(long-term memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009566"(fertilization)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038034|refseq:NP_001305762.1|refseq:NP_001276342.1|dip:DIP-34461N refseq:NP_003961.3|ensembl:ENSG00000036448(gene)|ensembl:ENSG00000274137(gene)|ensembl:ENST00000262113(transcript)|ensembl:ENST00000616680(transcript)|go:"GO:0002074"(extraocular skeletal muscle development)|go:"GO:0005739"(mitochondrion)|go:"GO:0006936"(muscle contraction)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0019900"(kinase binding)|go:"GO:0031430"(M band)|go:"GO:0032982"(myosin filament)|go:"GO:0045214"(sarcomere organization)|go:"GO:0051015"(actin filament binding)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036116|interpro:IPR036179|mint:P54296 - - comment:"author score: 27" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dblr0h0KBVa6kvaDHhnynRuHE6E9606 rogid:gSesKAbSCyJPbR2ryXwCMI0Y4vE9606 rigid:N2K6bjx/ymg9ftd6qkp/M7Qo5ZM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96KQ7 uniprotkb:Q9H582 intact:EBI-744366|uniprotkb:B0UZY2|uniprotkb:Q14349|uniprotkb:Q6PK06|uniprotkb:Q96MH5|uniprotkb:Q96QD0|uniprotkb:Q9UQL8|uniprotkb:Q9Y331|uniprotkb:Q5JQ92|uniprotkb:Q5JP83|uniprotkb:Q5JQA1|uniprotkb:Q5JQG3|ensembl:ENSP00000364687|ensembl:ENSP00000372864|ensembl:ENSP00000392305|ensembl:ENSP00000396119|ensembl:ENSP00000406110|ensembl:ENSP00000416957 intact:EBI-2560435|uniprotkb:Q7LG67|uniprotkb:Q5TCC0|uniprotkb:Q6PI06|uniprotkb:Q9ULJ9|uniprotkb:A2RU71|uniprotkb:Q2TAM0|uniprotkb:Q6P446|uniprotkb:Q6BEP7|ensembl:ENSP00000337008|ensembl:ENSP00000359469 psi-mi:ehmt2_human(display_long)|uniprotkb:KMT1C(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 3(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 8(gene name synonym)|uniprotkb:Protein G9a(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1C(gene name synonym)|uniprotkb:EHMT2(gene name)|psi-mi:EHMT2(display_short)|uniprotkb:BAT8(gene name synonym)|uniprotkb:G9A(gene name synonym)|uniprotkb:NG36(gene name synonym)|uniprotkb:C6orf30(gene name synonym) psi-mi:zn644_human(display_long)|uniprotkb:ZNF644(gene name)|psi-mi:ZNF644(display_short)|uniprotkb:KIAA1221(gene name synonym)|uniprotkb:ZEP2(gene name synonym)|uniprotkb:Zinc finger motif enhancer-binding protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478242|imex:IM-26985-85 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006700.3|refseq:NP_079532.5|interpro:IPR043550|mint:Q96KQ7|rcsb pdb:2O8J|rcsb pdb:3DM1|rcsb pdb:3K5K|rcsb pdb:3RJW|rcsb pdb:4NVQ|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5TTF|rcsb pdb:5TUY|rcsb pdb:5V9I|rcsb pdb:5VSC|rcsb pdb:5VSE|rcsb pdb:6MM1|rcsb pdb:7BTV|rcsb pdb:7BUC|rcsb pdb:7DCF|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-6804760|reactome:R-HSA-73762|reactome:R-HSA-8853884|reactome:R-HSA-8953750|ensembl:ENSG00000204371(gene)|ensembl:ENSG00000206376(gene)|ensembl:ENSG00000227333(gene)|ensembl:ENSG00000232045(gene)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035265"(organ growth)|go:"GO:0035690"|go:"GO:0036166"(phenotypic switching)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045471"(response to ethanol)|ensembl:ENSG00000236759(gene)|ensembl:ENSG00000238134(gene)|ensembl:ENST00000375537(transcript)|ensembl:ENST00000383373(transcript)|ensembl:ENST00000420336(transcript)|ensembl:ENST00000421926(transcript)|ensembl:ENST00000429506(transcript)|ensembl:ENST00000450075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006306"(DNA methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007286"(spermatid development)|go:"GO:0007616"(long-term memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009566"(fertilization)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038034|refseq:NP_001305762.1|refseq:NP_001276342.1|dip:DIP-34461N refseq:NP_057704.2|refseq:NP_115562.3|refseq:NP_958357.1|refseq:XP_016857977.1|refseq:XP_016857978.1|refseq:XP_016857979.1|refseq:XP_016857980.1|refseq:XP_016857981.1|refseq:XP_016857982.1|refseq:XP_016857983.1|ensembl:ENSG00000122482(gene)|ensembl:ENST00000337393(transcript)|ensembl:ENST00000370440(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9H582 - - comment:"author score: 44" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dblr0h0KBVa6kvaDHhnynRuHE6E9606 rogid:16MjfkV6aoDArzVV5Qi0K2HI2lg9606 rigid:N2K6bjx/ymg9ftd6qkp/M7Qo5ZM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96KQ7 uniprotkb:O95785 intact:EBI-744366|uniprotkb:B0UZY2|uniprotkb:Q14349|uniprotkb:Q6PK06|uniprotkb:Q96MH5|uniprotkb:Q96QD0|uniprotkb:Q9UQL8|uniprotkb:Q9Y331|uniprotkb:Q5JQ92|uniprotkb:Q5JP83|uniprotkb:Q5JQA1|uniprotkb:Q5JQG3|ensembl:ENSP00000364687|ensembl:ENSP00000372864|ensembl:ENSP00000392305|ensembl:ENSP00000396119|ensembl:ENSP00000406110|ensembl:ENSP00000416957 intact:EBI-1387294|uniprotkb:B7ZM82|uniprotkb:Q4G0E0|uniprotkb:Q6P6B0|uniprotkb:Q6ZN24|uniprotkb:Q7LDY6|uniprotkb:Q7LDZ1|uniprotkb:Q96IG5|uniprotkb:Q96SQ6|uniprotkb:Q9BUR8|uniprotkb:Q9NPT1|intact:EBI-10967552|uniprotkb:B3KVH1|uniprotkb:M0QY21 psi-mi:ehmt2_human(display_long)|uniprotkb:KMT1C(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 3(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 8(gene name synonym)|uniprotkb:Protein G9a(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1C(gene name synonym)|uniprotkb:EHMT2(gene name)|psi-mi:EHMT2(display_short)|uniprotkb:BAT8(gene name synonym)|uniprotkb:G9A(gene name synonym)|uniprotkb:NG36(gene name synonym)|uniprotkb:C6orf30(gene name synonym) psi-mi:wiz_human(display_long)|uniprotkb:WIZ(gene name)|psi-mi:WIZ(display_short)|uniprotkb:ZNF803(gene name synonym)|uniprotkb:Widely-interspaced zinc finger-containing protein(gene name synonym)|uniprotkb:Zinc finger protein 803(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478242|imex:IM-26985-85 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006700.3|refseq:NP_079532.5|interpro:IPR043550|mint:Q96KQ7|rcsb pdb:2O8J|rcsb pdb:3DM1|rcsb pdb:3K5K|rcsb pdb:3RJW|rcsb pdb:4NVQ|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5TTF|rcsb pdb:5TUY|rcsb pdb:5V9I|rcsb pdb:5VSC|rcsb pdb:5VSE|rcsb pdb:6MM1|rcsb pdb:7BTV|rcsb pdb:7BUC|rcsb pdb:7DCF|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-6804760|reactome:R-HSA-73762|reactome:R-HSA-8853884|reactome:R-HSA-8953750|ensembl:ENSG00000204371(gene)|ensembl:ENSG00000206376(gene)|ensembl:ENSG00000227333(gene)|ensembl:ENSG00000232045(gene)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035265"(organ growth)|go:"GO:0035690"|go:"GO:0036166"(phenotypic switching)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045471"(response to ethanol)|ensembl:ENSG00000236759(gene)|ensembl:ENSG00000238134(gene)|ensembl:ENST00000375537(transcript)|ensembl:ENST00000383373(transcript)|ensembl:ENST00000420336(transcript)|ensembl:ENST00000421926(transcript)|ensembl:ENST00000429506(transcript)|ensembl:ENST00000450075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006306"(DNA methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007286"(spermatid development)|go:"GO:0007616"(long-term memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009566"(fertilization)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038034|refseq:NP_001305762.1|refseq:NP_001276342.1|dip:DIP-34461N refseq:NP_067064.2|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001317324.1|interpro:IPR036236|mint:O95785|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010571"(positive regulation of nuclear cell cycle DNA replication)|go:"GO:0030496"(midbody)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990226"(histone methyltransferase binding) - - comment:"author score: 60" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dblr0h0KBVa6kvaDHhnynRuHE6E9606 rogid:FMQwuMDlEC/Zdsnayyl7kpQSmyg9606 rigid:N2K6bjx/ymg9ftd6qkp/M7Qo5ZM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96KQ7 uniprotkb:Q9H9B1 intact:EBI-744366|uniprotkb:B0UZY2|uniprotkb:Q14349|uniprotkb:Q6PK06|uniprotkb:Q96MH5|uniprotkb:Q96QD0|uniprotkb:Q9UQL8|uniprotkb:Q9Y331|uniprotkb:Q5JQ92|uniprotkb:Q5JP83|uniprotkb:Q5JQA1|uniprotkb:Q5JQG3|ensembl:ENSP00000364687|ensembl:ENSP00000372864|ensembl:ENSP00000392305|ensembl:ENSP00000396119|ensembl:ENSP00000406110|ensembl:ENSP00000416957 intact:EBI-766087|uniprotkb:Q8TCN7|uniprotkb:Q96F53|uniprotkb:Q96JF1|uniprotkb:Q96KH4|uniprotkb:B1AQ58|uniprotkb:B1AQ59|uniprotkb:Q86X08|ensembl:ENSP00000417980 psi-mi:ehmt2_human(display_long)|uniprotkb:KMT1C(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 3(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 2(gene name synonym)|uniprotkb:HLA-B-associated transcript 8(gene name synonym)|uniprotkb:Protein G9a(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1C(gene name synonym)|uniprotkb:EHMT2(gene name)|psi-mi:EHMT2(display_short)|uniprotkb:BAT8(gene name synonym)|uniprotkb:G9A(gene name synonym)|uniprotkb:NG36(gene name synonym)|uniprotkb:C6orf30(gene name synonym) psi-mi:ehmt1_human(display_long)|uniprotkb:KMT1D(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 5(gene name synonym)|uniprotkb:Euchromatic histone-lysine N-methyltransferase 1(gene name synonym)|uniprotkb:G9a-like protein 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1D(gene name synonym)|uniprotkb:EHMT1(gene name)|psi-mi:EHMT1(display_short)|uniprotkb:EUHMTASE1(gene name synonym)|uniprotkb:KIAA1876(gene name synonym)|uniprotkb:GLP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478242|imex:IM-26985-85 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006700.3|refseq:NP_079532.5|interpro:IPR043550|mint:Q96KQ7|rcsb pdb:2O8J|rcsb pdb:3DM1|rcsb pdb:3K5K|rcsb pdb:3RJW|rcsb pdb:4NVQ|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5TTF|rcsb pdb:5TUY|rcsb pdb:5V9I|rcsb pdb:5VSC|rcsb pdb:5VSE|rcsb pdb:6MM1|rcsb pdb:7BTV|rcsb pdb:7BUC|rcsb pdb:7DCF|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-6804760|reactome:R-HSA-73762|reactome:R-HSA-8853884|reactome:R-HSA-8953750|ensembl:ENSG00000204371(gene)|ensembl:ENSG00000206376(gene)|ensembl:ENSG00000227333(gene)|ensembl:ENSG00000232045(gene)|go:"GO:0010424"(DNA methylation on cytosine within a CG sequence)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035265"(organ growth)|go:"GO:0035690"|go:"GO:0036166"(phenotypic switching)|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045471"(response to ethanol)|ensembl:ENSG00000236759(gene)|ensembl:ENSG00000238134(gene)|ensembl:ENST00000375537(transcript)|ensembl:ENST00000383373(transcript)|ensembl:ENST00000420336(transcript)|ensembl:ENST00000421926(transcript)|ensembl:ENST00000429506(transcript)|ensembl:ENST00000450075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006306"(DNA methylation)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007286"(spermatid development)|go:"GO:0007616"(long-term memory)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009566"(fertilization)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048665"(neuron fate specification)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071314"(cellular response to cocaine)|go:"GO:1902902"(negative regulation of autophagosome assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038034|refseq:NP_001305762.1|refseq:NP_001276342.1|dip:DIP-34461N refseq:NP_001138999.1|refseq:NP_079033.4|ensembl:ENST00000371394|ensembl:ENSP00000485945|ensembl:ENSP00000417980|ensembl:ENST00000462484|ensembl:ENSP00000417328|dip:DIP-34585N|ensembl:ENSG00000181090(gene)|ensembl:ENST00000460843(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0016604"(nuclear body)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045995"(regulation of embryonic development)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0060992"(response to fungicide)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR001214(SET)|interpro:IPR002110(Ankyrin)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038035|interpro:IPR043550|mint:Q9H9B1|rcsb pdb:2IGQ|rcsb pdb:2RFI|rcsb pdb:3B7B|rcsb pdb:3B95|rcsb pdb:3FPD|rcsb pdb:3HNA|rcsb pdb:3MO0|rcsb pdb:3MO2|rcsb pdb:3MO5|rcsb pdb:3SW9|rcsb pdb:3SWC|rcsb pdb:4I51|rcsb pdb:5TTG|rcsb pdb:5TUZ|rcsb pdb:5V9J|rcsb pdb:5VSD|rcsb pdb:5VSF|rcsb pdb:6BY9|rcsb pdb:6MBO|rcsb pdb:6MBP|reactome:R-HSA-2559582|reactome:R-HSA-3214841|reactome:R-HSA-6804760|reactome:R-HSA-8853884|reactome:R-HSA-8953750 - - comment:"author score: 66" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dblr0h0KBVa6kvaDHhnynRuHE6E9606 rogid:4L6QOGSsRPi8hDjS2/BYShjpnf89606 rigid:N2K6bjx/ymg9ftd6qkp/M7Qo5ZM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UM07 uniprotkb:Q6IA86 intact:EBI-1042511|uniprotkb:Q5VTZ8|uniprotkb:Q70SX4|uniprotkb:A8K392|uniprotkb:B2RBW0|ensembl:ENSP00000364597|ensembl:ENSP00000487021 intact:EBI-2680411|uniprotkb:Q53GZ0|uniprotkb:Q8N5C2|uniprotkb:Q9H9N0|uniprotkb:Q96GV4|uniprotkb:Q687Y8|uniprotkb:Q9NV81|uniprotkb:Q96PI7|uniprotkb:B4DTG0|uniprotkb:A8KAI6|uniprotkb:B4DXP0|uniprotkb:E7EP23|uniprotkb:E9PCX0|intact:EBI-28972003|ensembl:ENSP00000350967 psi-mi:padi4_human(display_long)|uniprotkb:PADI4(gene name)|psi-mi:PADI4(display_short)|uniprotkb:PADI5(gene name synonym)|uniprotkb:PDI5(gene name synonym)|uniprotkb:Protein-arginine deiminase type IV(gene name synonym)|uniprotkb:Peptidylarginine deiminase IV(gene name synonym)|uniprotkb:HL-60 PAD(gene name synonym)|uniprotkb:PAD4(gene name synonym) psi-mi:elp2_human(display_long)|uniprotkb:STATIP1(gene name synonym)|uniprotkb:SHINC-2(gene name synonym)|uniprotkb:STAT3-interacting protein 1(gene name synonym)|uniprotkb:ELP2(gene name)|psi-mi:ELP2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25478341|imex:IM-26985-87 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036519.2|ensembl:ENSG00000159339(gene)|ensembl:ENSG00000280908(gene)|ensembl:ENST00000375448(transcript)|ensembl:ENST00000628229(transcript)|go:"GO:0004668"(protein-arginine deiminase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0018101"(protein citrullination)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034618"(arginine binding)|go:"GO:0036413"(histone H3-R26 citrullination)|go:"GO:0036414"(histone citrullination)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR004303(Protein-arginine deiminase)|interpro:IPR008972(Cupredoxin)|interpro:IPR013530(Protein-arginine deiminase, C-terminal)|interpro:IPR013732("Protein-arginine deiminase (PAD) N-terminal")|interpro:IPR013733("Protein-arginine deiminase (PAD) central region")|interpro:IPR036556|interpro:IPR038685|mint:Q9UM07|rcsb pdb:1WD8|rcsb pdb:1WD9|rcsb pdb:1WDA|rcsb pdb:2DEW|rcsb pdb:2DEX|rcsb pdb:2DEY|rcsb pdb:2DW5|rcsb pdb:3APM|rcsb pdb:3APN|rcsb pdb:3B1T|rcsb pdb:3B1U|rcsb pdb:4DKT|rcsb pdb:4X8C|rcsb pdb:4X8G|rcsb pdb:5N0M|rcsb pdb:5N0Y|rcsb pdb:5N0Z|rcsb pdb:5N1B|reactome:R-HSA-3247509|dip:DIP-50397N ensembl:ENST00000350494|ensembl:ENSP00000316051|ensembl:ENST00000351393|ensembl:ENSP00000257191|ensembl:ENSP00000350967|ensembl:ENST00000423854|ensembl:ENSP00000391202|ensembl:ENST00000442325|ensembl:ENSP00000414851|ensembl:ENST00000539560|ensembl:ENSP00000443555|ensembl:ENST00000542824|ensembl:ENSP00000443800|refseq:NP_001229804.1|refseq:NP_001229805.1|refseq:NP_001229806.1|refseq:NP_001229807.1|refseq:NP_001229808.1|refseq:NP_060725.1|dip:DIP-56235N|ensembl:ENSG00000134759(gene)|ensembl:ENST00000358232(transcript)|go:"GO:0002098"(tRNA wobble uridine modification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0033588"(elongator holoenzyme complex)|go:"GO:0046425"(regulation of receptor signaling pathway via JAK-STAT)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037289|mint:Q6IA86|reactome:R-HSA-3214847 - comment:"author score: 23" - figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wr0T9z51tfvyT0h062Juwgnn3jM9606 rogid:CkQQYyJ00MHOYXKhvVnwgAhdP2M9606 rigid:hKOy94RM1cnqLkYfRq5yYTYuDlE false - tandem tag:n-n - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99814 uniprotkb:P24928 intact:EBI-447470|uniprotkb:Q86VA2|uniprotkb:Q99630|ensembl:ENSP00000263734 intact:EBI-295301|uniprotkb:A6NN93|uniprotkb:B9EH88|uniprotkb:Q6NX41|intact:EBI-17957133|intact:EBI-14758660|intact:EBI-13324911|intact:EBI-23311874 psi-mi:epas1_human(display_long)|uniprotkb:EPAS1(gene name)|psi-mi:EPAS1(display_short)|uniprotkb:HIF2A(gene name synonym)|uniprotkb:MOP2(gene name synonym)|uniprotkb:Member of PAS protein 2(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP2(gene name synonym)|uniprotkb:BHLHE73(gene name synonym)|uniprotkb:PASD2(gene name synonym)|uniprotkb:Hypoxia-inducible factor 2-alpha(gene name synonym)|uniprotkb:HIF-1-alpha-like factor(gene name synonym)|uniprotkb:PAS domain-containing protein 2(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 73(gene name synonym) psi-mi:rpb1_human(display_long)|uniprotkb:POLR2A(gene name)|psi-mi:POLR2A(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit A(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:POLR2(gene name synonym)|uniprotkb:RNA-directed RNA polymerase II subunit RPB1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478370|imex:IM-26985-323 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001421.2|dip:DIP-32857N|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2000434"(regulation of protein neddylation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR014887(HIF-1 alpha C terminal transactivation domain)|interpro:IPR021537|interpro:IPR035965|interpro:IPR036638|mint:Q99814|rcsb pdb:1P97|rcsb pdb:2A24|rcsb pdb:3F1N|rcsb pdb:3F1O|rcsb pdb:3F1P|rcsb pdb:3H7W|rcsb pdb:3H82|rcsb pdb:4GHI|rcsb pdb:4GS9|rcsb pdb:4PKY|rcsb pdb:4XT2|rcsb pdb:5KIZ|rcsb pdb:5TBM|rcsb pdb:5UFP|rcsb pdb:6BVB|rcsb pdb:6CZW|rcsb pdb:6D09|rcsb pdb:6D0B|rcsb pdb:6D0C|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6X21|rcsb pdb:6X28|rcsb pdb:6X2H|rcsb pdb:6X37|rcsb pdb:6X3D|reactome:R-HSA-1234158|reactome:R-HSA-1234174|go:"GO:0048469"(cell maturation)|reactome:R-HSA-1234176|reactome:R-HSA-452723|reactome:R-HSA-8849473|reactome:R-HSA-8951664|reactome:R-HSA-9664873|ensembl:ENSG00000116016(gene)|ensembl:ENST00000263734(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007601"(visual perception)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030324"(lung development)|go:"GO:0042415"(norepinephrine metabolic process)|go:"GO:0043129"(surfactant homeostasis)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity) refseq:NP_000928.1|mint:P24928|dip:DIP-29011N|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0019900"(kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:2GHQ|rcsb pdb:2GHT|rcsb pdb:2LTO|rcsb pdb:3D9K|rcsb pdb:3D9L|rcsb pdb:3D9M|rcsb pdb:3D9N|rcsb pdb:3D9O|rcsb pdb:3D9P|rcsb pdb:4JXT|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:5M3H|rcsb pdb:5M3J|rcsb pdb:6DRD|rcsb pdb:6F5P|rcsb pdb:6G0R|rcsb pdb:6IC8|rcsb pdb:6IC9|rcsb pdb:6O9L|rcsb pdb:6Q5Y|rcsb pdb:6XKB|rcsb pdb:6XRE|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:rBmVytqL/OrXjDJxbgvsa8r98DI9606 rogid:Si2fgh4AMaNtlzvSQhvsuPusX7s9606 rigid:HFW/khVT4eDCeUpYxgAl2WbvwXY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99814 uniprotkb:P04908 intact:EBI-447470|uniprotkb:Q86VA2|uniprotkb:Q99630|ensembl:ENSP00000263734 intact:EBI-358971|uniprotkb:Q76P63|uniprotkb:P28001|ensembl:ENSP00000303373|ensembl:ENSP00000483842 psi-mi:epas1_human(display_long)|uniprotkb:EPAS1(gene name)|psi-mi:EPAS1(display_short)|uniprotkb:HIF2A(gene name synonym)|uniprotkb:MOP2(gene name synonym)|uniprotkb:Member of PAS protein 2(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP2(gene name synonym)|uniprotkb:BHLHE73(gene name synonym)|uniprotkb:PASD2(gene name synonym)|uniprotkb:Hypoxia-inducible factor 2-alpha(gene name synonym)|uniprotkb:HIF-1-alpha-like factor(gene name synonym)|uniprotkb:PAS domain-containing protein 2(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 73(gene name synonym) psi-mi:h2a1b_human(display_long)|uniprotkb:H2AC4(gene name)|psi-mi:H2AC4(display_short)|uniprotkb:H2AC8(gene name)|psi-mi:H2AC8(display_short)|uniprotkb:H2AFA(gene name synonym)|uniprotkb:H2AFM(gene name synonym)|uniprotkb:HIST1H2AB(gene name synonym)|uniprotkb:HIST1H2AE(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/a(gene name synonym)|uniprotkb:Histone H2A/m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478370|imex:IM-26985-323 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001421.2|dip:DIP-32857N|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2000434"(regulation of protein neddylation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR014887(HIF-1 alpha C terminal transactivation domain)|interpro:IPR021537|interpro:IPR035965|interpro:IPR036638|mint:Q99814|rcsb pdb:1P97|rcsb pdb:2A24|rcsb pdb:3F1N|rcsb pdb:3F1O|rcsb pdb:3F1P|rcsb pdb:3H7W|rcsb pdb:3H82|rcsb pdb:4GHI|rcsb pdb:4GS9|rcsb pdb:4PKY|rcsb pdb:4XT2|rcsb pdb:5KIZ|rcsb pdb:5TBM|rcsb pdb:5UFP|rcsb pdb:6BVB|rcsb pdb:6CZW|rcsb pdb:6D09|rcsb pdb:6D0B|rcsb pdb:6D0C|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6X21|rcsb pdb:6X28|rcsb pdb:6X2H|rcsb pdb:6X37|rcsb pdb:6X3D|reactome:R-HSA-1234158|reactome:R-HSA-1234174|go:"GO:0048469"(cell maturation)|reactome:R-HSA-1234176|reactome:R-HSA-452723|reactome:R-HSA-8849473|reactome:R-HSA-8951664|reactome:R-HSA-9664873|ensembl:ENSG00000116016(gene)|ensembl:ENST00000263734(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007601"(visual perception)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030324"(lung development)|go:"GO:0042415"(norepinephrine metabolic process)|go:"GO:0043129"(surfactant homeostasis)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity) refseq:NP_003504.2|refseq:NP_066390.1|ensembl:ENSG00000277075(gene)|ensembl:ENSG00000278463(gene)|ensembl:ENST00000303910(transcript)|ensembl:ENST00000615868(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P04908|rcsb pdb:2CV5|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1V|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACL|rcsb pdb:6AEE|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6KE9|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V92|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|rcsb pdb:6JXD|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|dip:DIP-44197N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:rBmVytqL/OrXjDJxbgvsa8r98DI9606 rogid:4Qno1mMYZB6FdNoojrzulWLVq849606 rigid:HFW/khVT4eDCeUpYxgAl2WbvwXY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99814 uniprotkb:P07477 intact:EBI-447470|uniprotkb:Q86VA2|uniprotkb:Q99630|ensembl:ENSP00000263734 intact:EBI-1222902|uniprotkb:A6NJ71|uniprotkb:Q92955|uniprotkb:Q9HAN4|uniprotkb:Q9HAN5|uniprotkb:Q9HAN6|uniprotkb:Q9HAN7|intact:EBI-1760472|intact:EBI-1965533|uniprotkb:A1A509|uniprotkb:Q5NV57|uniprotkb:Q7M4N3|uniprotkb:Q7M4N4|uniprotkb:B2R5I5|ensembl:ENSP00000308720|ensembl:ENSP00000479217 psi-mi:epas1_human(display_long)|uniprotkb:EPAS1(gene name)|psi-mi:EPAS1(display_short)|uniprotkb:HIF2A(gene name synonym)|uniprotkb:MOP2(gene name synonym)|uniprotkb:Member of PAS protein 2(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP2(gene name synonym)|uniprotkb:BHLHE73(gene name synonym)|uniprotkb:PASD2(gene name synonym)|uniprotkb:Hypoxia-inducible factor 2-alpha(gene name synonym)|uniprotkb:HIF-1-alpha-like factor(gene name synonym)|uniprotkb:PAS domain-containing protein 2(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 73(gene name synonym) psi-mi:try1_human(display_long)|uniprotkb:PRSS1(gene name)|psi-mi:PRSS1(display_short)|uniprotkb:TRP1(gene name synonym)|uniprotkb:TRY1(gene name synonym)|uniprotkb:TRYP1(gene name synonym)|uniprotkb:Trypsin I(gene name synonym)|uniprotkb:Cationic trypsinogen(gene name synonym)|uniprotkb:Serine protease 1(gene name synonym)|uniprotkb:Beta-trypsin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478370|imex:IM-26985-323 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001421.2|dip:DIP-32857N|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2000434"(regulation of protein neddylation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR014887(HIF-1 alpha C terminal transactivation domain)|interpro:IPR021537|interpro:IPR035965|interpro:IPR036638|mint:Q99814|rcsb pdb:1P97|rcsb pdb:2A24|rcsb pdb:3F1N|rcsb pdb:3F1O|rcsb pdb:3F1P|rcsb pdb:3H7W|rcsb pdb:3H82|rcsb pdb:4GHI|rcsb pdb:4GS9|rcsb pdb:4PKY|rcsb pdb:4XT2|rcsb pdb:5KIZ|rcsb pdb:5TBM|rcsb pdb:5UFP|rcsb pdb:6BVB|rcsb pdb:6CZW|rcsb pdb:6D09|rcsb pdb:6D0B|rcsb pdb:6D0C|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6X21|rcsb pdb:6X28|rcsb pdb:6X2H|rcsb pdb:6X37|rcsb pdb:6X3D|reactome:R-HSA-1234158|reactome:R-HSA-1234174|go:"GO:0048469"(cell maturation)|reactome:R-HSA-1234176|reactome:R-HSA-452723|reactome:R-HSA-8849473|reactome:R-HSA-8951664|reactome:R-HSA-9664873|ensembl:ENSG00000116016(gene)|ensembl:ENST00000263734(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007601"(visual perception)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030324"(lung development)|go:"GO:0042415"(norepinephrine metabolic process)|go:"GO:0043129"(surfactant homeostasis)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity) refseq:NP_002760.1|ensembl:ENSG00000204983(gene)|ensembl:ENSG00000274247(gene)|ensembl:ENST00000311737(transcript)|ensembl:ENST00000616256(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0007586"(digestion)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0072562"(blood microparticle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|mint:P07477|rcsb pdb:1FXY|rcsb pdb:1TRN|rcsb pdb:2RA3|rcsb pdb:4WWY|rcsb pdb:4WXV|reactome:R-HSA-1592389|reactome:R-HSA-196741 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:rBmVytqL/OrXjDJxbgvsa8r98DI9606 rogid:2elS/qMYj0sflxilyWfk3KPtGmo9606 rigid:HFW/khVT4eDCeUpYxgAl2WbvwXY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99814 uniprotkb:Q9NQG5 intact:EBI-447470|uniprotkb:Q86VA2|uniprotkb:Q99630|ensembl:ENSP00000263734 intact:EBI-747925|uniprotkb:Q1WDE7|uniprotkb:Q6PKF4|ensembl:ENSP00000362532 psi-mi:epas1_human(display_long)|uniprotkb:EPAS1(gene name)|psi-mi:EPAS1(display_short)|uniprotkb:HIF2A(gene name synonym)|uniprotkb:MOP2(gene name synonym)|uniprotkb:Member of PAS protein 2(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP2(gene name synonym)|uniprotkb:BHLHE73(gene name synonym)|uniprotkb:PASD2(gene name synonym)|uniprotkb:Hypoxia-inducible factor 2-alpha(gene name synonym)|uniprotkb:HIF-1-alpha-like factor(gene name synonym)|uniprotkb:PAS domain-containing protein 2(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 73(gene name synonym) psi-mi:rpr1b_human(display_long)|uniprotkb:RPRD1B(gene name)|psi-mi:RPRD1B(display_short)|uniprotkb:C20orf77(gene name synonym)|uniprotkb:CREPT(gene name synonym)|uniprotkb:Cell cycle-related and expression-elevated protein in tumor(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478370|imex:IM-26985-323 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001421.2|dip:DIP-32857N|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2000434"(regulation of protein neddylation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR014887(HIF-1 alpha C terminal transactivation domain)|interpro:IPR021537|interpro:IPR035965|interpro:IPR036638|mint:Q99814|rcsb pdb:1P97|rcsb pdb:2A24|rcsb pdb:3F1N|rcsb pdb:3F1O|rcsb pdb:3F1P|rcsb pdb:3H7W|rcsb pdb:3H82|rcsb pdb:4GHI|rcsb pdb:4GS9|rcsb pdb:4PKY|rcsb pdb:4XT2|rcsb pdb:5KIZ|rcsb pdb:5TBM|rcsb pdb:5UFP|rcsb pdb:6BVB|rcsb pdb:6CZW|rcsb pdb:6D09|rcsb pdb:6D0B|rcsb pdb:6D0C|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6X21|rcsb pdb:6X28|rcsb pdb:6X2H|rcsb pdb:6X37|rcsb pdb:6X3D|reactome:R-HSA-1234158|reactome:R-HSA-1234174|go:"GO:0048469"(cell maturation)|reactome:R-HSA-1234176|reactome:R-HSA-452723|reactome:R-HSA-8849473|reactome:R-HSA-8951664|reactome:R-HSA-9664873|ensembl:ENSG00000116016(gene)|ensembl:ENST00000263734(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007601"(visual perception)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030324"(lung development)|go:"GO:0042415"(norepinephrine metabolic process)|go:"GO:0043129"(surfactant homeostasis)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity) refseq:NP_067038.1|ensembl:ENSG00000101413(gene)|ensembl:ENST00000373433(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q9NQG5|rcsb pdb:4FLA|rcsb pdb:4FU3|rcsb pdb:4HFG|rcsb pdb:4NAD|rcsb pdb:4Q94|rcsb pdb:4Q96|reactome:R-HSA-6807505|dip:DIP-61537N - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:rBmVytqL/OrXjDJxbgvsa8r98DI9606 rogid:1P0sOiLV5eQXrRj+vENpc6L/z/Q9606 rigid:HFW/khVT4eDCeUpYxgAl2WbvwXY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99814 uniprotkb:P19388 intact:EBI-447470|uniprotkb:Q86VA2|uniprotkb:Q99630|ensembl:ENSP00000263734 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 psi-mi:epas1_human(display_long)|uniprotkb:EPAS1(gene name)|psi-mi:EPAS1(display_short)|uniprotkb:HIF2A(gene name synonym)|uniprotkb:MOP2(gene name synonym)|uniprotkb:Member of PAS protein 2(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP2(gene name synonym)|uniprotkb:BHLHE73(gene name synonym)|uniprotkb:PASD2(gene name synonym)|uniprotkb:Hypoxia-inducible factor 2-alpha(gene name synonym)|uniprotkb:HIF-1-alpha-like factor(gene name synonym)|uniprotkb:PAS domain-containing protein 2(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 73(gene name synonym) psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478370|imex:IM-26985-323 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001421.2|dip:DIP-32857N|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2000434"(regulation of protein neddylation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR014887(HIF-1 alpha C terminal transactivation domain)|interpro:IPR021537|interpro:IPR035965|interpro:IPR036638|mint:Q99814|rcsb pdb:1P97|rcsb pdb:2A24|rcsb pdb:3F1N|rcsb pdb:3F1O|rcsb pdb:3F1P|rcsb pdb:3H7W|rcsb pdb:3H82|rcsb pdb:4GHI|rcsb pdb:4GS9|rcsb pdb:4PKY|rcsb pdb:4XT2|rcsb pdb:5KIZ|rcsb pdb:5TBM|rcsb pdb:5UFP|rcsb pdb:6BVB|rcsb pdb:6CZW|rcsb pdb:6D09|rcsb pdb:6D0B|rcsb pdb:6D0C|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6X21|rcsb pdb:6X28|rcsb pdb:6X2H|rcsb pdb:6X37|rcsb pdb:6X3D|reactome:R-HSA-1234158|reactome:R-HSA-1234174|go:"GO:0048469"(cell maturation)|reactome:R-HSA-1234176|reactome:R-HSA-452723|reactome:R-HSA-8849473|reactome:R-HSA-8951664|reactome:R-HSA-9664873|ensembl:ENSG00000116016(gene)|ensembl:ENST00000263734(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007601"(visual perception)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030324"(lung development)|go:"GO:0042415"(norepinephrine metabolic process)|go:"GO:0043129"(surfactant homeostasis)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:rBmVytqL/OrXjDJxbgvsa8r98DI9606 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rigid:HFW/khVT4eDCeUpYxgAl2WbvwXY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99814 uniprotkb:P19387 intact:EBI-447470|uniprotkb:Q86VA2|uniprotkb:Q99630|ensembl:ENSP00000263734 intact:EBI-394729|uniprotkb:O15161|ensembl:ENSP00000219252 psi-mi:epas1_human(display_long)|uniprotkb:EPAS1(gene name)|psi-mi:EPAS1(display_short)|uniprotkb:HIF2A(gene name synonym)|uniprotkb:MOP2(gene name synonym)|uniprotkb:Member of PAS protein 2(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP2(gene name synonym)|uniprotkb:BHLHE73(gene name synonym)|uniprotkb:PASD2(gene name synonym)|uniprotkb:Hypoxia-inducible factor 2-alpha(gene name synonym)|uniprotkb:HIF-1-alpha-like factor(gene name synonym)|uniprotkb:PAS domain-containing protein 2(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 73(gene name synonym) psi-mi:rpb3_human(display_long)|uniprotkb:POLR2C(gene name)|psi-mi:POLR2C(display_short)|uniprotkb:A-152E5.7(orf name)|uniprotkb:DNA-directed RNA polymerase II subunit C(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 33 kDa polypeptide(gene name synonym)|uniprotkb:RPB31(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478370|imex:IM-26985-323 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001421.2|dip:DIP-32857N|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2000434"(regulation of protein neddylation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR014887(HIF-1 alpha C terminal transactivation domain)|interpro:IPR021537|interpro:IPR035965|interpro:IPR036638|mint:Q99814|rcsb pdb:1P97|rcsb pdb:2A24|rcsb pdb:3F1N|rcsb pdb:3F1O|rcsb pdb:3F1P|rcsb pdb:3H7W|rcsb pdb:3H82|rcsb pdb:4GHI|rcsb pdb:4GS9|rcsb pdb:4PKY|rcsb pdb:4XT2|rcsb pdb:5KIZ|rcsb pdb:5TBM|rcsb pdb:5UFP|rcsb pdb:6BVB|rcsb pdb:6CZW|rcsb pdb:6D09|rcsb pdb:6D0B|rcsb pdb:6D0C|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6X21|rcsb pdb:6X28|rcsb pdb:6X2H|rcsb pdb:6X37|rcsb pdb:6X3D|reactome:R-HSA-1234158|reactome:R-HSA-1234174|go:"GO:0048469"(cell maturation)|reactome:R-HSA-1234176|reactome:R-HSA-452723|reactome:R-HSA-8849473|reactome:R-HSA-8951664|reactome:R-HSA-9664873|ensembl:ENSG00000116016(gene)|ensembl:ENST00000263734(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007601"(visual perception)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030324"(lung development)|go:"GO:0042415"(norepinephrine metabolic process)|go:"GO:0043129"(surfactant homeostasis)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity) refseq:NP_116558.1|ensembl:ENSG00000102978(gene)|ensembl:ENST00000219252(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001514(DNA-directed RNA polymerase, 30-40 kDa subunit, conserved site)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR036603|interpro:IPR036643|mint:P19387|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32911N - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:rBmVytqL/OrXjDJxbgvsa8r98DI9606 rogid:UXFC+i+QqB2WRgL9OiYSQ66L36c9606 rigid:HFW/khVT4eDCeUpYxgAl2WbvwXY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99814 uniprotkb:P52434 intact:EBI-447470|uniprotkb:Q86VA2|uniprotkb:Q99630|ensembl:ENSP00000263734 intact:EBI-359505|uniprotkb:P53802|uniprotkb:Q969R0|ensembl:ENSP00000392913|uniprotkb:C9J413|uniprotkb:C9JBJ6|uniprotkb:C9JCU7|uniprotkb:C9JUA8 psi-mi:epas1_human(display_long)|uniprotkb:EPAS1(gene name)|psi-mi:EPAS1(display_short)|uniprotkb:HIF2A(gene name synonym)|uniprotkb:MOP2(gene name synonym)|uniprotkb:Member of PAS protein 2(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP2(gene name synonym)|uniprotkb:BHLHE73(gene name synonym)|uniprotkb:PASD2(gene name synonym)|uniprotkb:Hypoxia-inducible factor 2-alpha(gene name synonym)|uniprotkb:HIF-1-alpha-like factor(gene name synonym)|uniprotkb:PAS domain-containing protein 2(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 73(gene name synonym) psi-mi:rpab3_human(display_long)|uniprotkb:POLR2H(gene name)|psi-mi:POLR2H(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit H(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I, II, and III 17.1 kDa polypeptide(gene name synonym)|uniprotkb:RPB17(gene name synonym)|uniprotkb:RPB8 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478370|imex:IM-26985-323 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001421.2|dip:DIP-32857N|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2000434"(regulation of protein neddylation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR014887(HIF-1 alpha C terminal transactivation domain)|interpro:IPR021537|interpro:IPR035965|interpro:IPR036638|mint:Q99814|rcsb pdb:1P97|rcsb pdb:2A24|rcsb pdb:3F1N|rcsb pdb:3F1O|rcsb pdb:3F1P|rcsb pdb:3H7W|rcsb pdb:3H82|rcsb pdb:4GHI|rcsb pdb:4GS9|rcsb pdb:4PKY|rcsb pdb:4XT2|rcsb pdb:5KIZ|rcsb pdb:5TBM|rcsb pdb:5UFP|rcsb pdb:6BVB|rcsb pdb:6CZW|rcsb pdb:6D09|rcsb pdb:6D0B|rcsb pdb:6D0C|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6X21|rcsb pdb:6X28|rcsb pdb:6X2H|rcsb pdb:6X37|rcsb pdb:6X3D|reactome:R-HSA-1234158|reactome:R-HSA-1234174|go:"GO:0048469"(cell maturation)|reactome:R-HSA-1234176|reactome:R-HSA-452723|reactome:R-HSA-8849473|reactome:R-HSA-8951664|reactome:R-HSA-9664873|ensembl:ENSG00000116016(gene)|ensembl:ENST00000263734(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007601"(visual perception)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030324"(lung development)|go:"GO:0042415"(norepinephrine metabolic process)|go:"GO:0043129"(surfactant homeostasis)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity) ensembl:ENSG00000163882(gene)|ensembl:ENST00000456318(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032993"(protein-DNA complex)|interpro:IPR005570(RNA polymerase, Rpb8)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:P52434|rcsb pdb:2F3I|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|refseq:NP_006223.2|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|rcsb pdb:7AE3|reactome:R-HSA-1834949|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-427413|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-203927|refseq:NP_001265627.1|refseq:NP_001265628.1|refseq:NP_001265629.1|refseq:NP_001265644.1|refseq:NP_001265643.1|refseq:XP_006713729.1|refseq:XP_006713730.1|refseq:XP_016862125.1|refseq:XP_016862126.1|dip:DIP-27556N - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:rBmVytqL/OrXjDJxbgvsa8r98DI9606 rogid:h7BRWDi8wRbnw/FcFo25bnlVNkE9606 rigid:HFW/khVT4eDCeUpYxgAl2WbvwXY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99814 uniprotkb:P36954 intact:EBI-447470|uniprotkb:Q86VA2|uniprotkb:Q99630|ensembl:ENSP00000263734 intact:EBI-395202|uniprotkb:Q6NW05|uniprotkb:B2R5J2|ensembl:ENSP00000221859 psi-mi:epas1_human(display_long)|uniprotkb:EPAS1(gene name)|psi-mi:EPAS1(display_short)|uniprotkb:HIF2A(gene name synonym)|uniprotkb:MOP2(gene name synonym)|uniprotkb:Member of PAS protein 2(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP2(gene name synonym)|uniprotkb:BHLHE73(gene name synonym)|uniprotkb:PASD2(gene name synonym)|uniprotkb:Hypoxia-inducible factor 2-alpha(gene name synonym)|uniprotkb:HIF-1-alpha-like factor(gene name synonym)|uniprotkb:PAS domain-containing protein 2(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 73(gene name synonym) psi-mi:rpb9_human(display_long)|uniprotkb:POLR2I(gene name)|psi-mi:POLR2I(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit I(gene name synonym)|uniprotkb:RNA polymerase II 14.5 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478370|imex:IM-26985-323 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001421.2|dip:DIP-32857N|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2000434"(regulation of protein neddylation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR014887(HIF-1 alpha C terminal transactivation domain)|interpro:IPR021537|interpro:IPR035965|interpro:IPR036638|mint:Q99814|rcsb pdb:1P97|rcsb pdb:2A24|rcsb pdb:3F1N|rcsb pdb:3F1O|rcsb pdb:3F1P|rcsb pdb:3H7W|rcsb pdb:3H82|rcsb pdb:4GHI|rcsb pdb:4GS9|rcsb pdb:4PKY|rcsb pdb:4XT2|rcsb pdb:5KIZ|rcsb pdb:5TBM|rcsb pdb:5UFP|rcsb pdb:6BVB|rcsb pdb:6CZW|rcsb pdb:6D09|rcsb pdb:6D0B|rcsb pdb:6D0C|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6X21|rcsb pdb:6X28|rcsb pdb:6X2H|rcsb pdb:6X37|rcsb pdb:6X3D|reactome:R-HSA-1234158|reactome:R-HSA-1234174|go:"GO:0048469"(cell maturation)|reactome:R-HSA-1234176|reactome:R-HSA-452723|reactome:R-HSA-8849473|reactome:R-HSA-8951664|reactome:R-HSA-9664873|ensembl:ENSG00000116016(gene)|ensembl:ENST00000263734(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007601"(visual perception)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030324"(lung development)|go:"GO:0042415"(norepinephrine metabolic process)|go:"GO:0043129"(surfactant homeostasis)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity) refseq:NP_006224.1|ensembl:ENSG00000105258(gene)|ensembl:ENST00000221859(transcript)|go:"GO:0001193"(maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034012|mint:P36954|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32917N - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:rBmVytqL/OrXjDJxbgvsa8r98DI9606 rogid:YZUW2UDzj1RhCC46iaX1LvYayNA9606 rigid:HFW/khVT4eDCeUpYxgAl2WbvwXY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99814 uniprotkb:Q8NGY3 intact:EBI-447470|uniprotkb:Q86VA2|uniprotkb:Q99630|ensembl:ENSP00000263734 intact:EBI-25478350|ensembl:ENSP00000357128|uniprotkb:Q5VUV0|uniprotkb:Q6IFR5 psi-mi:epas1_human(display_long)|uniprotkb:EPAS1(gene name)|psi-mi:EPAS1(display_short)|uniprotkb:HIF2A(gene name synonym)|uniprotkb:MOP2(gene name synonym)|uniprotkb:Member of PAS protein 2(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP2(gene name synonym)|uniprotkb:BHLHE73(gene name synonym)|uniprotkb:PASD2(gene name synonym)|uniprotkb:Hypoxia-inducible factor 2-alpha(gene name synonym)|uniprotkb:HIF-1-alpha-like factor(gene name synonym)|uniprotkb:PAS domain-containing protein 2(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 73(gene name synonym) psi-mi:or6k3_human(display_long)|uniprotkb:OR6K3(gene name)|psi-mi:OR6K3(display_short)|uniprotkb:Olfactory receptor OR1-18(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478370|imex:IM-26985-323 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001421.2|dip:DIP-32857N|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2000434"(regulation of protein neddylation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR014887(HIF-1 alpha C terminal transactivation domain)|interpro:IPR021537|interpro:IPR035965|interpro:IPR036638|mint:Q99814|rcsb pdb:1P97|rcsb pdb:2A24|rcsb pdb:3F1N|rcsb pdb:3F1O|rcsb pdb:3F1P|rcsb pdb:3H7W|rcsb pdb:3H82|rcsb pdb:4GHI|rcsb pdb:4GS9|rcsb pdb:4PKY|rcsb pdb:4XT2|rcsb pdb:5KIZ|rcsb pdb:5TBM|rcsb pdb:5UFP|rcsb pdb:6BVB|rcsb pdb:6CZW|rcsb pdb:6D09|rcsb pdb:6D0B|rcsb pdb:6D0C|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6X21|rcsb pdb:6X28|rcsb pdb:6X2H|rcsb pdb:6X37|rcsb pdb:6X3D|reactome:R-HSA-1234158|reactome:R-HSA-1234174|go:"GO:0048469"(cell maturation)|reactome:R-HSA-1234176|reactome:R-HSA-452723|reactome:R-HSA-8849473|reactome:R-HSA-8951664|reactome:R-HSA-9664873|ensembl:ENSG00000116016(gene)|ensembl:ENST00000263734(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007601"(visual perception)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030324"(lung development)|go:"GO:0042415"(norepinephrine metabolic process)|go:"GO:0043129"(surfactant homeostasis)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity) interpro:IPR000276(GPCR, rhodopsin-like)|interpro:IPR000725(Olfactory receptor)|interpro:IPR017452(GPCR, rhodopsin-like superfamily)|mint:Q8NGY3|reactome:R-HSA-381753|go:"GO:0050911"(detection of chemical stimulus involved in sensory perception of smell)|ensembl:ENSG00000203757(gene)|ensembl:ENST00000368146(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0004984"(olfactory receptor activity)|go:"GO:0005549"(odorant binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|refseq:NP_001005327.2 - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:rBmVytqL/OrXjDJxbgvsa8r98DI9606 rogid:OsMUqVKCg4T6+S/HB4JVI8A/Eow9606 rigid:HFW/khVT4eDCeUpYxgAl2WbvwXY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99814 uniprotkb:P06702 intact:EBI-447470|uniprotkb:Q86VA2|uniprotkb:Q99630|ensembl:ENSP00000263734 intact:EBI-1055001|uniprotkb:Q6FGA1|uniprotkb:Q9NYM0|uniprotkb:Q9UCJ1|uniprotkb:D3DV36|ensembl:ENSP00000357727 psi-mi:epas1_human(display_long)|uniprotkb:EPAS1(gene name)|psi-mi:EPAS1(display_short)|uniprotkb:HIF2A(gene name synonym)|uniprotkb:MOP2(gene name synonym)|uniprotkb:Member of PAS protein 2(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP2(gene name synonym)|uniprotkb:BHLHE73(gene name synonym)|uniprotkb:PASD2(gene name synonym)|uniprotkb:Hypoxia-inducible factor 2-alpha(gene name synonym)|uniprotkb:HIF-1-alpha-like factor(gene name synonym)|uniprotkb:PAS domain-containing protein 2(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 73(gene name synonym) psi-mi:s10a9_human(display_long)|uniprotkb:S100 calcium-binding protein A9(gene name synonym)|uniprotkb:Calgranulin-B(gene name synonym)|uniprotkb:Migration inhibitory factor-related protein 14(gene name synonym)|uniprotkb:Leukocyte L1 complex heavy chain(gene name synonym)|uniprotkb:Calprotectin L1H subunit(gene name synonym)|uniprotkb:S100A9(gene name)|psi-mi:S100A9(display_short)|uniprotkb:CAGB(gene name synonym)|uniprotkb:CFAG(gene name synonym)|uniprotkb:MRP14(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478370|imex:IM-26985-323 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001421.2|dip:DIP-32857N|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2000434"(regulation of protein neddylation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR014887(HIF-1 alpha C terminal transactivation domain)|interpro:IPR021537|interpro:IPR035965|interpro:IPR036638|mint:Q99814|rcsb pdb:1P97|rcsb pdb:2A24|rcsb pdb:3F1N|rcsb pdb:3F1O|rcsb pdb:3F1P|rcsb pdb:3H7W|rcsb pdb:3H82|rcsb pdb:4GHI|rcsb pdb:4GS9|rcsb pdb:4PKY|rcsb pdb:4XT2|rcsb pdb:5KIZ|rcsb pdb:5TBM|rcsb pdb:5UFP|rcsb pdb:6BVB|rcsb pdb:6CZW|rcsb pdb:6D09|rcsb pdb:6D0B|rcsb pdb:6D0C|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6X21|rcsb pdb:6X28|rcsb pdb:6X2H|rcsb pdb:6X37|rcsb pdb:6X3D|reactome:R-HSA-1234158|reactome:R-HSA-1234174|go:"GO:0048469"(cell maturation)|reactome:R-HSA-1234176|reactome:R-HSA-452723|reactome:R-HSA-8849473|reactome:R-HSA-8951664|reactome:R-HSA-9664873|ensembl:ENSG00000116016(gene)|ensembl:ENST00000263734(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007601"(visual perception)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030324"(lung development)|go:"GO:0042415"(norepinephrine metabolic process)|go:"GO:0043129"(surfactant homeostasis)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity) refseq:NP_002956.1|rcsb pdb:1XK4|rcsb pdb:4GGF|rcsb pdb:4XJK|rcsb pdb:5I8N|rcsb pdb:5W1F|rcsb pdb:6DS2|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5668599|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-6799990|ensembl:ENSG00000163220(gene)|ensembl:ENST00000368738(transcript)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035662"(Toll-like receptor 4 binding)|go:"GO:0035821"(modulation of process of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0045113"(regulation of integrin biosynthetic process)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070488"(neutrophil aggregation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|mint:P06702|rcsb pdb:1IRJ|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016209"(antioxidant activity)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0030054"(cell junction)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032119"(sequestering of zinc ion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035425"(autocrine signaling)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|dip:DIP-1166N - - comment:"author score: 31" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:rBmVytqL/OrXjDJxbgvsa8r98DI9606 rogid:IGnX4DSnv8xMr5pY4T7X7vYos5A9606 rigid:HFW/khVT4eDCeUpYxgAl2WbvwXY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99814 uniprotkb:O15514 intact:EBI-447470|uniprotkb:Q86VA2|uniprotkb:Q99630|ensembl:ENSP00000263734 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 psi-mi:epas1_human(display_long)|uniprotkb:EPAS1(gene name)|psi-mi:EPAS1(display_short)|uniprotkb:HIF2A(gene name synonym)|uniprotkb:MOP2(gene name synonym)|uniprotkb:Member of PAS protein 2(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP2(gene name synonym)|uniprotkb:BHLHE73(gene name synonym)|uniprotkb:PASD2(gene name synonym)|uniprotkb:Hypoxia-inducible factor 2-alpha(gene name synonym)|uniprotkb:HIF-1-alpha-like factor(gene name synonym)|uniprotkb:PAS domain-containing protein 2(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 73(gene name synonym) psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478370|imex:IM-26985-323 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001421.2|dip:DIP-32857N|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2000434"(regulation of protein neddylation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR014887(HIF-1 alpha C terminal transactivation domain)|interpro:IPR021537|interpro:IPR035965|interpro:IPR036638|mint:Q99814|rcsb pdb:1P97|rcsb pdb:2A24|rcsb pdb:3F1N|rcsb pdb:3F1O|rcsb pdb:3F1P|rcsb pdb:3H7W|rcsb pdb:3H82|rcsb pdb:4GHI|rcsb pdb:4GS9|rcsb pdb:4PKY|rcsb pdb:4XT2|rcsb pdb:5KIZ|rcsb pdb:5TBM|rcsb pdb:5UFP|rcsb pdb:6BVB|rcsb pdb:6CZW|rcsb pdb:6D09|rcsb pdb:6D0B|rcsb pdb:6D0C|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6X21|rcsb pdb:6X28|rcsb pdb:6X2H|rcsb pdb:6X37|rcsb pdb:6X3D|reactome:R-HSA-1234158|reactome:R-HSA-1234174|go:"GO:0048469"(cell maturation)|reactome:R-HSA-1234176|reactome:R-HSA-452723|reactome:R-HSA-8849473|reactome:R-HSA-8951664|reactome:R-HSA-9664873|ensembl:ENSG00000116016(gene)|ensembl:ENST00000263734(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007601"(visual perception)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030324"(lung development)|go:"GO:0042415"(norepinephrine metabolic process)|go:"GO:0043129"(surfactant homeostasis)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity) refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N - - comment:"author score: 31" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:rBmVytqL/OrXjDJxbgvsa8r98DI9606 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rigid:HFW/khVT4eDCeUpYxgAl2WbvwXY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99814 uniprotkb:P62487 intact:EBI-447470|uniprotkb:Q86VA2|uniprotkb:Q99630|ensembl:ENSP00000263734 intact:EBI-347928|ensembl:ENSP00000301788|uniprotkb:P52433|uniprotkb:Q2M1Z4|uniprotkb:B2R5C0 psi-mi:epas1_human(display_long)|uniprotkb:EPAS1(gene name)|psi-mi:EPAS1(display_short)|uniprotkb:HIF2A(gene name synonym)|uniprotkb:MOP2(gene name synonym)|uniprotkb:Member of PAS protein 2(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP2(gene name synonym)|uniprotkb:BHLHE73(gene name synonym)|uniprotkb:PASD2(gene name synonym)|uniprotkb:Hypoxia-inducible factor 2-alpha(gene name synonym)|uniprotkb:HIF-1-alpha-like factor(gene name synonym)|uniprotkb:PAS domain-containing protein 2(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 73(gene name synonym) psi-mi:rpb7_human(display_long)|uniprotkb:POLR2G(gene name)|psi-mi:POLR2G(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit G(gene name synonym)|uniprotkb:RPB7(gene name synonym)|uniprotkb:RNA polymerase II 19 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478370|imex:IM-26985-323 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001421.2|dip:DIP-32857N|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2000434"(regulation of protein neddylation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR014887(HIF-1 alpha C terminal transactivation domain)|interpro:IPR021537|interpro:IPR035965|interpro:IPR036638|mint:Q99814|rcsb pdb:1P97|rcsb pdb:2A24|rcsb pdb:3F1N|rcsb pdb:3F1O|rcsb pdb:3F1P|rcsb pdb:3H7W|rcsb pdb:3H82|rcsb pdb:4GHI|rcsb pdb:4GS9|rcsb pdb:4PKY|rcsb pdb:4XT2|rcsb pdb:5KIZ|rcsb pdb:5TBM|rcsb pdb:5UFP|rcsb pdb:6BVB|rcsb pdb:6CZW|rcsb pdb:6D09|rcsb pdb:6D0B|rcsb pdb:6D0C|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6X21|rcsb pdb:6X28|rcsb pdb:6X2H|rcsb pdb:6X37|rcsb pdb:6X3D|reactome:R-HSA-1234158|reactome:R-HSA-1234174|go:"GO:0048469"(cell maturation)|reactome:R-HSA-1234176|reactome:R-HSA-452723|reactome:R-HSA-8849473|reactome:R-HSA-8951664|reactome:R-HSA-9664873|ensembl:ENSG00000116016(gene)|ensembl:ENST00000263734(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007601"(visual perception)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030324"(lung development)|go:"GO:0042415"(norepinephrine metabolic process)|go:"GO:0043129"(surfactant homeostasis)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity) ensembl:ENSG00000168002(gene)|ensembl:ENST00000301788(transcript)|go:"GO:0000291"(nuclear-transcribed mRNA catabolic process, exonucleolytic)|go:"GO:0000932"(P-body)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006915"(apoptotic process)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR003029(S1, RNA binding)|interpro:IPR005576(RNA polymerase Rpb7, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR036898|mint:P62487|rcsb pdb:2C35|rcsb pdb:5IYA|rcsb pdb:5IY6|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|rcsb pdb:5IY7|reactome:R-HSA-167200|reactome:R-HSA-167238|rcsb pdb:5IY8|rcsb pdb:5IY9|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-5601884|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|refseq:NP_002687.1|dip:DIP-32663N - - comment:"author score: 34" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:rBmVytqL/OrXjDJxbgvsa8r98DI9606 rogid:MtnIweuhSqLFov0c40uOiwv8Eas9606 rigid:HFW/khVT4eDCeUpYxgAl2WbvwXY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99814 uniprotkb:P01040 intact:EBI-447470|uniprotkb:Q86VA2|uniprotkb:Q99630|ensembl:ENSP00000263734 intact:EBI-724303|ensembl:ENSP00000264474|uniprotkb:Q6IB90 psi-mi:epas1_human(display_long)|uniprotkb:EPAS1(gene name)|psi-mi:EPAS1(display_short)|uniprotkb:HIF2A(gene name synonym)|uniprotkb:MOP2(gene name synonym)|uniprotkb:Member of PAS protein 2(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP2(gene name synonym)|uniprotkb:BHLHE73(gene name synonym)|uniprotkb:PASD2(gene name synonym)|uniprotkb:Hypoxia-inducible factor 2-alpha(gene name synonym)|uniprotkb:HIF-1-alpha-like factor(gene name synonym)|uniprotkb:PAS domain-containing protein 2(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 73(gene name synonym) psi-mi:cyta_human(display_long)|uniprotkb:Cystatin-AS(gene name synonym)|uniprotkb:Stefin-A(gene name synonym)|uniprotkb:CSTA(gene name)|psi-mi:CSTA(display_short)|uniprotkb:STF1(gene name synonym)|uniprotkb:STFA(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478370|imex:IM-26985-323 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001421.2|dip:DIP-32857N|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2000434"(regulation of protein neddylation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR014887(HIF-1 alpha C terminal transactivation domain)|interpro:IPR021537|interpro:IPR035965|interpro:IPR036638|mint:Q99814|rcsb pdb:1P97|rcsb pdb:2A24|rcsb pdb:3F1N|rcsb pdb:3F1O|rcsb pdb:3F1P|rcsb pdb:3H7W|rcsb pdb:3H82|rcsb pdb:4GHI|rcsb pdb:4GS9|rcsb pdb:4PKY|rcsb pdb:4XT2|rcsb pdb:5KIZ|rcsb pdb:5TBM|rcsb pdb:5UFP|rcsb pdb:6BVB|rcsb pdb:6CZW|rcsb pdb:6D09|rcsb pdb:6D0B|rcsb pdb:6D0C|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6X21|rcsb pdb:6X28|rcsb pdb:6X2H|rcsb pdb:6X37|rcsb pdb:6X3D|reactome:R-HSA-1234158|reactome:R-HSA-1234174|go:"GO:0048469"(cell maturation)|reactome:R-HSA-1234176|reactome:R-HSA-452723|reactome:R-HSA-8849473|reactome:R-HSA-8951664|reactome:R-HSA-9664873|ensembl:ENSG00000116016(gene)|ensembl:ENST00000263734(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007601"(visual perception)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030324"(lung development)|go:"GO:0042415"(norepinephrine metabolic process)|go:"GO:0043129"(surfactant homeostasis)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity) refseq:NP_005204.1|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR001713(Proteinase inhibitor I25A, stefin A)|mint:P01040|rcsb pdb:1CYU|rcsb pdb:1CYV|rcsb pdb:1DVC|rcsb pdb:1DVD|rcsb pdb:1GD3|rcsb pdb:1GD4|rcsb pdb:1N9J|rcsb pdb:1NB3|rcsb pdb:1NB5|rcsb pdb:3K9M|rcsb pdb:3KFQ|interpro:IPR018073|rcsb pdb:3KSE|reactome:R-HSA-6809371|ensembl:ENSG00000121552(gene)|ensembl:ENST00000264474(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002020"(protease binding)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0045861"(negative regulation of proteolysis) - - comment:"author score: 34" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:rBmVytqL/OrXjDJxbgvsa8r98DI9606 rogid:SzbpyWUHlOtItIvffzuwhcqFsDI9606 rigid:HFW/khVT4eDCeUpYxgAl2WbvwXY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99814 uniprotkb:P27540 intact:EBI-447470|uniprotkb:Q86VA2|uniprotkb:Q99630|ensembl:ENSP00000263734 intact:EBI-80809|uniprotkb:C4AMA1|ensembl:ENSP00000351407|uniprotkb:B2R9H1|uniprotkb:F8WAP6|uniprotkb:Q59ED4|uniprotkb:Q5QP39|uniprotkb:Q8NDC7 psi-mi:epas1_human(display_long)|uniprotkb:EPAS1(gene name)|psi-mi:EPAS1(display_short)|uniprotkb:HIF2A(gene name synonym)|uniprotkb:MOP2(gene name synonym)|uniprotkb:Member of PAS protein 2(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP2(gene name synonym)|uniprotkb:BHLHE73(gene name synonym)|uniprotkb:PASD2(gene name synonym)|uniprotkb:Hypoxia-inducible factor 2-alpha(gene name synonym)|uniprotkb:HIF-1-alpha-like factor(gene name synonym)|uniprotkb:PAS domain-containing protein 2(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 73(gene name synonym) psi-mi:arnt_human(display_long)|uniprotkb:ARNT(gene name)|psi-mi:ARNT(display_short)|uniprotkb:Dioxin receptor, nuclear translocator(gene name synonym)|uniprotkb:Hypoxia-inducible factor 1-beta(gene name synonym)|uniprotkb:BHLHE2(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478370|imex:IM-26985-323 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001421.2|dip:DIP-32857N|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2000434"(regulation of protein neddylation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR014887(HIF-1 alpha C terminal transactivation domain)|interpro:IPR021537|interpro:IPR035965|interpro:IPR036638|mint:Q99814|rcsb pdb:1P97|rcsb pdb:2A24|rcsb pdb:3F1N|rcsb pdb:3F1O|rcsb pdb:3F1P|rcsb pdb:3H7W|rcsb pdb:3H82|rcsb pdb:4GHI|rcsb pdb:4GS9|rcsb pdb:4PKY|rcsb pdb:4XT2|rcsb pdb:5KIZ|rcsb pdb:5TBM|rcsb pdb:5UFP|rcsb pdb:6BVB|rcsb pdb:6CZW|rcsb pdb:6D09|rcsb pdb:6D0B|rcsb pdb:6D0C|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6X21|rcsb pdb:6X28|rcsb pdb:6X2H|rcsb pdb:6X37|rcsb pdb:6X3D|reactome:R-HSA-1234158|reactome:R-HSA-1234174|go:"GO:0048469"(cell maturation)|reactome:R-HSA-1234176|reactome:R-HSA-452723|reactome:R-HSA-8849473|reactome:R-HSA-8951664|reactome:R-HSA-9664873|ensembl:ENSG00000116016(gene)|ensembl:ENST00000263734(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007601"(visual perception)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030324"(lung development)|go:"GO:0042415"(norepinephrine metabolic process)|go:"GO:0043129"(surfactant homeostasis)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity) ensembl:ENSG00000143437(gene)|ensembl:ENST00000358595(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0016604"(nuclear body)|go:"GO:0017162"(aryl hydrocarbon receptor binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030949"(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0033235"(positive regulation of protein sumoylation)|go:"GO:0034751"(aryl hydrocarbon receptor complex)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045821"(positive regulation of glycolytic process)|refseq:NP_001184254.1|refseq:NP_001659.1|refseq:NP_848514.1|refseq:NP_001272964.1|refseq:NP_001272965.1|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046886"(positive regulation of hormone biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013767(PAS fold)|interpro:IPR035965|interpro:IPR036638|mint:P27540|rcsb pdb:1D7G|rcsb pdb:1X0O|rcsb pdb:2A24|rcsb pdb:2ARN|rcsb pdb:2B02|rcsb pdb:2HV1|rcsb pdb:2K7S|rcsb pdb:3F1N|rcsb pdb:3F1O|rcsb pdb:3F1P|rcsb pdb:3H7W|rcsb pdb:6D09|rcsb pdb:6D0B|rcsb pdb:6D0C|rcsb pdb:6X21|rcsb pdb:3H82|rcsb pdb:6X28|rcsb pdb:6X2H|rcsb pdb:6X37|rcsb pdb:6X3D|rcsb pdb:4EQ1|rcsb pdb:4GHI|rcsb pdb:4GS9|rcsb pdb:4H6J|rcsb pdb:4LPZ|rcsb pdb:4PKY|rcsb pdb:4XT2|reactome:R-HSA-1234158|rcsb pdb:5TBM|reactome:R-HSA-1989781|reactome:R-HSA-211945|rcsb pdb:5UFP|reactome:R-HSA-211976|reactome:R-HSA-211981|rcsb pdb:5V0L|rcsb pdb:6CZW|reactome:R-HSA-8937144|ensembl:ENST00000354396|ensembl:ENSP00000346372|ensembl:ENSP00000351407|ensembl:ENST00000505755|ensembl:ENSP00000427571|ensembl:ENST00000515192|ensembl:ENSP00000423851|refseq:XP_016856778.1|dip:DIP-30886N - - comment:"author score: 40" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:rBmVytqL/OrXjDJxbgvsa8r98DI9606 rogid:MAYVa32fLDGxgEr0VL9ZVg/EcIA9606 rigid:HFW/khVT4eDCeUpYxgAl2WbvwXY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99814 uniprotkb:P05109 intact:EBI-447470|uniprotkb:Q86VA2|uniprotkb:Q99630|ensembl:ENSP00000263734 intact:EBI-355281|uniprotkb:Q5SY70|uniprotkb:Q9UC92|uniprotkb:Q9UCJ0|uniprotkb:A8K5L3|uniprotkb:Q9UC84|uniprotkb:Q9UCM6|uniprotkb:D3DV37|ensembl:ENSP00000357721|ensembl:ENSP00000357722 psi-mi:epas1_human(display_long)|uniprotkb:EPAS1(gene name)|psi-mi:EPAS1(display_short)|uniprotkb:HIF2A(gene name synonym)|uniprotkb:MOP2(gene name synonym)|uniprotkb:Member of PAS protein 2(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP2(gene name synonym)|uniprotkb:BHLHE73(gene name synonym)|uniprotkb:PASD2(gene name synonym)|uniprotkb:Hypoxia-inducible factor 2-alpha(gene name synonym)|uniprotkb:HIF-1-alpha-like factor(gene name synonym)|uniprotkb:PAS domain-containing protein 2(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 73(gene name synonym) psi-mi:s10a8_human(display_long)|uniprotkb:S100A8(gene name)|psi-mi:S100A8(display_short)|uniprotkb:CAGA(gene name synonym)|uniprotkb:MRP8(gene name synonym)|uniprotkb:CFAG(gene name synonym)|uniprotkb:S100 calcium-binding protein A8(gene name synonym)|uniprotkb:Calgranulin-A(gene name synonym)|uniprotkb:Migration inhibitory factor-related protein 8(gene name synonym)|uniprotkb:Cystic fibrosis antigen(gene name synonym)|uniprotkb:Leukocyte L1 complex light chain(gene name synonym)|uniprotkb:Calprotectin L1L subunit(gene name synonym)|uniprotkb:Urinary stone protein band A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478370|imex:IM-26985-323 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001421.2|dip:DIP-32857N|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2000434"(regulation of protein neddylation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR014887(HIF-1 alpha C terminal transactivation domain)|interpro:IPR021537|interpro:IPR035965|interpro:IPR036638|mint:Q99814|rcsb pdb:1P97|rcsb pdb:2A24|rcsb pdb:3F1N|rcsb pdb:3F1O|rcsb pdb:3F1P|rcsb pdb:3H7W|rcsb pdb:3H82|rcsb pdb:4GHI|rcsb pdb:4GS9|rcsb pdb:4PKY|rcsb pdb:4XT2|rcsb pdb:5KIZ|rcsb pdb:5TBM|rcsb pdb:5UFP|rcsb pdb:6BVB|rcsb pdb:6CZW|rcsb pdb:6D09|rcsb pdb:6D0B|rcsb pdb:6D0C|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6X21|rcsb pdb:6X28|rcsb pdb:6X2H|rcsb pdb:6X37|rcsb pdb:6X3D|reactome:R-HSA-1234158|reactome:R-HSA-1234174|go:"GO:0048469"(cell maturation)|reactome:R-HSA-1234176|reactome:R-HSA-452723|reactome:R-HSA-8849473|reactome:R-HSA-8951664|reactome:R-HSA-9664873|ensembl:ENSG00000116016(gene)|ensembl:ENST00000263734(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007601"(visual perception)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030324"(lung development)|go:"GO:0042415"(norepinephrine metabolic process)|go:"GO:0043129"(surfactant homeostasis)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity) refseq:NP_001306126.1|refseq:NP_001306127.1|refseq:NP_001306130.1|refseq:NP_002955.2|go:"GO:0042060"(wound healing)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045471"(response to ethanol)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070488"(neutrophil aggregation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028474|go:"GO:0035662"(Toll-like receptor 4 binding)|mint:P05109|rcsb pdb:1MR8|rcsb pdb:1XK4|rcsb pdb:4GGF|rcsb pdb:4XJK|rcsb pdb:5HLO|rcsb pdb:5HLV|rcsb pdb:5W1F|rcsb pdb:6DS2|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5668599|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-6799990|ensembl:ENST00000368732(transcript)|ensembl:ENST00000368733(transcript)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002526"(acute inflammatory response)|ensembl:ENSG00000143546(gene)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0002793"(positive regulation of peptide secretion)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010043"(response to zinc ion)|go:"GO:0014002"(astrocyte development)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032119"(sequestering of zinc ion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035425"(autocrine signaling)|dip:DIP-1165N - - comment:"author score: 41" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:rBmVytqL/OrXjDJxbgvsa8r98DI9606 rogid:3Okfhj8fxclZ0Uo/Fa1Z89qC8Ec9606 rigid:HFW/khVT4eDCeUpYxgAl2WbvwXY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99814 uniprotkb:Q13617 intact:EBI-447470|uniprotkb:Q86VA2|uniprotkb:Q99630|ensembl:ENSP00000263734 intact:EBI-456179|uniprotkb:O00200|uniprotkb:Q5T2B6|uniprotkb:Q9UNF9|uniprotkb:D3DRY6|uniprotkb:B3KT95|uniprotkb:B7Z6K8|uniprotkb:G3V1S2|ensembl:ENSP00000363881|ensembl:ENSP00000363883|ensembl:ENSP00000501215|ensembl:ENSP00000363880 psi-mi:epas1_human(display_long)|uniprotkb:EPAS1(gene name)|psi-mi:EPAS1(display_short)|uniprotkb:HIF2A(gene name synonym)|uniprotkb:MOP2(gene name synonym)|uniprotkb:Member of PAS protein 2(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP2(gene name synonym)|uniprotkb:BHLHE73(gene name synonym)|uniprotkb:PASD2(gene name synonym)|uniprotkb:Hypoxia-inducible factor 2-alpha(gene name synonym)|uniprotkb:HIF-1-alpha-like factor(gene name synonym)|uniprotkb:PAS domain-containing protein 2(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 73(gene name synonym) psi-mi:cul2_human(display_long)|uniprotkb:CUL2(gene name)|psi-mi:CUL2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478370|imex:IM-26985-323 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001421.2|dip:DIP-32857N|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2000434"(regulation of protein neddylation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR014887(HIF-1 alpha C terminal transactivation domain)|interpro:IPR021537|interpro:IPR035965|interpro:IPR036638|mint:Q99814|rcsb pdb:1P97|rcsb pdb:2A24|rcsb pdb:3F1N|rcsb pdb:3F1O|rcsb pdb:3F1P|rcsb pdb:3H7W|rcsb pdb:3H82|rcsb pdb:4GHI|rcsb pdb:4GS9|rcsb pdb:4PKY|rcsb pdb:4XT2|rcsb pdb:5KIZ|rcsb pdb:5TBM|rcsb pdb:5UFP|rcsb pdb:6BVB|rcsb pdb:6CZW|rcsb pdb:6D09|rcsb pdb:6D0B|rcsb pdb:6D0C|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6X21|rcsb pdb:6X28|rcsb pdb:6X2H|rcsb pdb:6X37|rcsb pdb:6X3D|reactome:R-HSA-1234158|reactome:R-HSA-1234174|go:"GO:0048469"(cell maturation)|reactome:R-HSA-1234176|reactome:R-HSA-452723|reactome:R-HSA-8849473|reactome:R-HSA-8951664|reactome:R-HSA-9664873|ensembl:ENSG00000116016(gene)|ensembl:ENST00000263734(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007601"(visual perception)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030324"(lung development)|go:"GO:0042415"(norepinephrine metabolic process)|go:"GO:0043129"(surfactant homeostasis)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity) refseq:NP_001185706.1|refseq:NP_001185707.1|refseq:NP_001185708.1|refseq:NP_003582.2|refseq:XP_011518049.1|dip:DIP-31612N|ensembl:ENST00000374748(transcript)|ensembl:ENST00000374749(transcript)|ensembl:ENST00000374751(transcript)|ensembl:ENST00000673636(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0030891"(VCB complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031461"(cullin-RING ubiquitin ligase complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|interpro:IPR001373(Cullin, N-terminal region)|interpro:IPR016157(Cullin, conserved site)|interpro:IPR016158(Cullin homology)|interpro:IPR016159(Cullin repeat-like)|interpro:IPR019559|interpro:IPR036317|interpro:IPR036388|interpro:IPR036390|mint:Q13617|rcsb pdb:4WQO|rcsb pdb:5N4W|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|reactome:R-HSA-1234176|reactome:R-HSA-8951664|ensembl:ENSG00000108094(gene)|reactome:R-HSA-983168|reactome:R-HSA-9010553 - - comment:"author score: 71" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:rBmVytqL/OrXjDJxbgvsa8r98DI9606 rogid:ffttNV1NYH8UnmbHxf+ygcIG1wE9606 rigid:HFW/khVT4eDCeUpYxgAl2WbvwXY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99814 uniprotkb:Q15369 intact:EBI-447470|uniprotkb:Q86VA2|uniprotkb:Q99630|ensembl:ENSP00000263734 intact:EBI-301231|uniprotkb:Q567Q6|ensembl:ENSP00000284811|ensembl:ENSP00000428074|ensembl:ENSP00000428171|ensembl:ENSP00000428334|ensembl:ENSP00000429596|ensembl:ENSP00000429906|ensembl:ENSP00000478121|uniprotkb:E5RGD9 psi-mi:epas1_human(display_long)|uniprotkb:EPAS1(gene name)|psi-mi:EPAS1(display_short)|uniprotkb:HIF2A(gene name synonym)|uniprotkb:MOP2(gene name synonym)|uniprotkb:Member of PAS protein 2(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP2(gene name synonym)|uniprotkb:BHLHE73(gene name synonym)|uniprotkb:PASD2(gene name synonym)|uniprotkb:Hypoxia-inducible factor 2-alpha(gene name synonym)|uniprotkb:HIF-1-alpha-like factor(gene name synonym)|uniprotkb:PAS domain-containing protein 2(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 73(gene name synonym) psi-mi:eloc_human(display_long)|uniprotkb:ELOC(gene name)|psi-mi:ELOC(display_short)|uniprotkb:Elongin 15 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit C(gene name synonym)|uniprotkb:SIII p15(gene name synonym)|uniprotkb:TCEB1(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478370|imex:IM-26985-323 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001421.2|dip:DIP-32857N|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2000434"(regulation of protein neddylation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR014887(HIF-1 alpha C terminal transactivation domain)|interpro:IPR021537|interpro:IPR035965|interpro:IPR036638|mint:Q99814|rcsb pdb:1P97|rcsb pdb:2A24|rcsb pdb:3F1N|rcsb pdb:3F1O|rcsb pdb:3F1P|rcsb pdb:3H7W|rcsb pdb:3H82|rcsb pdb:4GHI|rcsb pdb:4GS9|rcsb pdb:4PKY|rcsb pdb:4XT2|rcsb pdb:5KIZ|rcsb pdb:5TBM|rcsb pdb:5UFP|rcsb pdb:6BVB|rcsb pdb:6CZW|rcsb pdb:6D09|rcsb pdb:6D0B|rcsb pdb:6D0C|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6X21|rcsb pdb:6X28|rcsb pdb:6X2H|rcsb pdb:6X37|rcsb pdb:6X3D|reactome:R-HSA-1234158|reactome:R-HSA-1234174|go:"GO:0048469"(cell maturation)|reactome:R-HSA-1234176|reactome:R-HSA-452723|reactome:R-HSA-8849473|reactome:R-HSA-8951664|reactome:R-HSA-9664873|ensembl:ENSG00000116016(gene)|ensembl:ENST00000263734(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007601"(visual perception)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030324"(lung development)|go:"GO:0042415"(norepinephrine metabolic process)|go:"GO:0043129"(surfactant homeostasis)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity) refseq:NP_005639.1|refseq:NP_001191786.1|refseq:NP_001191787.1|refseq:NP_001191788.1|refseq:NP_001191789.1|refseq:NP_001191790.1|refseq:NP_001191791.1|refseq:NP_001191792.1|refseq:NP_001191793.1|ensembl:ENSG00000154582(gene)|ensembl:ENST00000284811(transcript)|ensembl:ENST00000518127(transcript)|ensembl:ENST00000519487(transcript)|ensembl:ENST00000520242(transcript)|ensembl:ENST00000522337(transcript)|ensembl:ENST00000523815(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0070449"(elongin complex)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|mint:Q15369|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|ensembl:ENST00000622804(transcript)|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:4WQO|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:6HAX|rcsb pdb:6GFY|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7N|rcsb pdb:6SIS|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-167200|refseq:XP_011515882.1|refseq:XP_011515883.1|dip:DIP-29571N - - comment:"author score: 82" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:rBmVytqL/OrXjDJxbgvsa8r98DI9606 rogid:Ngvkh3YoddZoutF3Vgwdi2b6xz49606 rigid:HFW/khVT4eDCeUpYxgAl2WbvwXY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99814 uniprotkb:Q15370 intact:EBI-447470|uniprotkb:Q86VA2|uniprotkb:Q99630|ensembl:ENSP00000263734 intact:EBI-301238|ensembl:ENSP00000386652|uniprotkb:B7WPD3 psi-mi:epas1_human(display_long)|uniprotkb:EPAS1(gene name)|psi-mi:EPAS1(display_short)|uniprotkb:HIF2A(gene name synonym)|uniprotkb:MOP2(gene name synonym)|uniprotkb:Member of PAS protein 2(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP2(gene name synonym)|uniprotkb:BHLHE73(gene name synonym)|uniprotkb:PASD2(gene name synonym)|uniprotkb:Hypoxia-inducible factor 2-alpha(gene name synonym)|uniprotkb:HIF-1-alpha-like factor(gene name synonym)|uniprotkb:PAS domain-containing protein 2(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 73(gene name synonym) psi-mi:elob_human(display_long)|uniprotkb:ELOB(gene name)|psi-mi:ELOB(display_short)|uniprotkb:Elongin 18 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit B(gene name synonym)|uniprotkb:SIII p18(gene name synonym)|uniprotkb:TCEB2(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478370|imex:IM-26985-323 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001421.2|dip:DIP-32857N|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2000434"(regulation of protein neddylation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR014887(HIF-1 alpha C terminal transactivation domain)|interpro:IPR021537|interpro:IPR035965|interpro:IPR036638|mint:Q99814|rcsb pdb:1P97|rcsb pdb:2A24|rcsb pdb:3F1N|rcsb pdb:3F1O|rcsb pdb:3F1P|rcsb pdb:3H7W|rcsb pdb:3H82|rcsb pdb:4GHI|rcsb pdb:4GS9|rcsb pdb:4PKY|rcsb pdb:4XT2|rcsb pdb:5KIZ|rcsb pdb:5TBM|rcsb pdb:5UFP|rcsb pdb:6BVB|rcsb pdb:6CZW|rcsb pdb:6D09|rcsb pdb:6D0B|rcsb pdb:6D0C|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6X21|rcsb pdb:6X28|rcsb pdb:6X2H|rcsb pdb:6X37|rcsb pdb:6X3D|reactome:R-HSA-1234158|reactome:R-HSA-1234174|go:"GO:0048469"(cell maturation)|reactome:R-HSA-1234176|reactome:R-HSA-452723|reactome:R-HSA-8849473|reactome:R-HSA-8951664|reactome:R-HSA-9664873|ensembl:ENSG00000116016(gene)|ensembl:ENST00000263734(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007601"(visual perception)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030324"(lung development)|go:"GO:0042415"(norepinephrine metabolic process)|go:"GO:0043129"(surfactant homeostasis)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity) ensembl:ENSG00000103363(gene)|ensembl:ENST00000409906(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030891"(VCB complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070449"(elongin complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR039049|mint:Q15370|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2JZ3|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFY|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:4WQO|rcsb pdb:6HAX|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:6SIS|refseq:NP_009039.1|refseq:NP_996896.1|dip:DIP-29570N - - comment:"author score: 94" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:rBmVytqL/OrXjDJxbgvsa8r98DI9606 rogid:apX4QFpDC4Dz3MAs7tQ8+XFHx6I9606 rigid:HFW/khVT4eDCeUpYxgAl2WbvwXY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99814 uniprotkb:P40337 intact:EBI-447470|uniprotkb:Q86VA2|uniprotkb:Q99630|ensembl:ENSP00000263734 intact:EBI-301246|uniprotkb:Q13599|uniprotkb:B2RE45|uniprotkb:Q6PDA9|ensembl:ENSP00000256474 psi-mi:epas1_human(display_long)|uniprotkb:EPAS1(gene name)|psi-mi:EPAS1(display_short)|uniprotkb:HIF2A(gene name synonym)|uniprotkb:MOP2(gene name synonym)|uniprotkb:Member of PAS protein 2(gene name synonym)|uniprotkb:Basic-helix-loop-helix-PAS protein MOP2(gene name synonym)|uniprotkb:BHLHE73(gene name synonym)|uniprotkb:PASD2(gene name synonym)|uniprotkb:Hypoxia-inducible factor 2-alpha(gene name synonym)|uniprotkb:HIF-1-alpha-like factor(gene name synonym)|uniprotkb:PAS domain-containing protein 2(gene name synonym)|uniprotkb:Class E basic helix-loop-helix protein 73(gene name synonym) psi-mi:vhl_human(display_long)|uniprotkb:VHL(gene name)|psi-mi:VHL(display_short)|uniprotkb:pVHL(gene name synonym)|uniprotkb:Protein G7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478370|imex:IM-26985-323 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001421.2|dip:DIP-32857N|go:"GO:0048625"(myoblast fate commitment)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:2000434"(regulation of protein neddylation)|interpro:IPR000014(PAS)|interpro:IPR001067(Nuclear translocator)|interpro:IPR001610(PAC motif)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR013655(PAS fold-3)|interpro:IPR013767(PAS fold)|interpro:IPR014887(HIF-1 alpha C terminal transactivation domain)|interpro:IPR021537|interpro:IPR035965|interpro:IPR036638|mint:Q99814|rcsb pdb:1P97|rcsb pdb:2A24|rcsb pdb:3F1N|rcsb pdb:3F1O|rcsb pdb:3F1P|rcsb pdb:3H7W|rcsb pdb:3H82|rcsb pdb:4GHI|rcsb pdb:4GS9|rcsb pdb:4PKY|rcsb pdb:4XT2|rcsb pdb:5KIZ|rcsb pdb:5TBM|rcsb pdb:5UFP|rcsb pdb:6BVB|rcsb pdb:6CZW|rcsb pdb:6D09|rcsb pdb:6D0B|rcsb pdb:6D0C|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6X21|rcsb pdb:6X28|rcsb pdb:6X2H|rcsb pdb:6X37|rcsb pdb:6X3D|reactome:R-HSA-1234158|reactome:R-HSA-1234174|go:"GO:0048469"(cell maturation)|reactome:R-HSA-1234176|reactome:R-HSA-452723|reactome:R-HSA-8849473|reactome:R-HSA-8951664|reactome:R-HSA-9664873|ensembl:ENSG00000116016(gene)|ensembl:ENST00000263734(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002027"(regulation of heart rate)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007601"(visual perception)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030324"(lung development)|go:"GO:0042415"(norepinephrine metabolic process)|go:"GO:0043129"(surfactant homeostasis)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity) rcsb pdb:6BVB|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:4W9I|rcsb pdb:6GFX|rcsb pdb:6GFY|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:4W9J|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:6HAX|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:4W9K|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6SIS|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-1234176|reactome:R-HSA-3232142|rcsb pdb:4W9L|reactome:R-HSA-8951664|rcsb pdb:4WQO|reactome:R-HSA-9682706|reactome:R-HSA-9694686|reactome:R-HSA-9706019|reactome:R-HSA-983168|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|ensembl:ENSG00000134086(gene)|ensembl:ENST00000256474(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006508"(proteolysis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0050821"(protein stabilization)|go:"GO:0061418"(regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR002714(Tumour suppressor protein, von Hippel-Lindau disease)|interpro:IPR022772|interpro:IPR024048|interpro:IPR024053|interpro:IPR036208|interpro:IPR037139|interpro:IPR037140|mint:P40337|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|refseq:NP_000542.1|refseq:NP_937799.1|dip:DIP-32585N - - comment:"author score: 104" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:rBmVytqL/OrXjDJxbgvsa8r98DI9606 rogid:KaCKDTSj0xPG9YmfFsXIbkRt3A89606 rigid:HFW/khVT4eDCeUpYxgAl2WbvwXY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQT5 uniprotkb:Q8TF46 intact:EBI-371866|uniprotkb:Q5QP85|uniprotkb:Q9Y3A8|ensembl:ENSP00000323046|uniprotkb:A8K0K6 intact:EBI-3672244|uniprotkb:Q8N1N8|uniprotkb:Q8WTU9|uniprotkb:Q96CM7|ensembl:ENSP00000321711 psi-mi:exos3_human(display_long)|uniprotkb:EXOSC3(gene name)|psi-mi:EXOSC3(display_short)|uniprotkb:RRP40(gene name synonym)|uniprotkb:CGI-102(orf name)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:p10(gene name synonym) psi-mi:di3l1_human(display_long)|uniprotkb:DIS3L1(gene name synonym)|uniprotkb:DIS3L(gene name)|psi-mi:DIS3L(display_short)|uniprotkb:KIAA1955(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478433|imex:IM-26985-539 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001002269.1|refseq:NP_057126.2|ensembl:ENSG00000107371(gene)|ensembl:ENST00000327304(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q9NQT5|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29847N refseq:NP_001137160.1|refseq:NP_588616.1|refseq:NP_001310865.1|refseq:NP_001310867.1|refseq:NP_001310868.1|refseq:NP_001310870.1|refseq:NP_001310874.1|refseq:NP_001310875.1|ensembl:ENSG00000166938(gene)|ensembl:ENST00000319212(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0019899"(enzyme binding)|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022966|interpro:IPR031192|interpro:IPR033770|interpro:IPR033771|interpro:IPR041505|mint:Q8TF46 - - comment:"author score: 109" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZyFFgoy7HM3oZ35I16XAH3jCook9606 rogid:rxO2GoLqsuS4+/zLJsqCU8LFQyw9606 rigid:CLGIHQBQBZ132ObLsork5lvdm/Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQT5 uniprotkb:Q9Y450 intact:EBI-371866|uniprotkb:Q5QP85|uniprotkb:Q9Y3A8|ensembl:ENSP00000323046|uniprotkb:A8K0K6 intact:EBI-2868258|uniprotkb:Q5T7G3|uniprotkb:Q4VX90|uniprotkb:Q4VX89|uniprotkb:Q9UPW3|uniprotkb:Q8NDW9|uniprotkb:B7Z365|ensembl:ENSP00000356811 psi-mi:exos3_human(display_long)|uniprotkb:EXOSC3(gene name)|psi-mi:EXOSC3(display_short)|uniprotkb:RRP40(gene name synonym)|uniprotkb:CGI-102(orf name)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:p10(gene name synonym) psi-mi:hbs1l_human(display_long)|uniprotkb:HBS1L(gene name)|psi-mi:HBS1L(display_short)|uniprotkb:HBS1(gene name synonym)|uniprotkb:KIAA1038(gene name synonym)|uniprotkb:ERFS(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478433|imex:IM-26985-539 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001002269.1|refseq:NP_057126.2|ensembl:ENSG00000107371(gene)|ensembl:ENST00000327304(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q9NQT5|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29847N refseq:NP_001138630.1|refseq:NP_001138679.1|refseq:NP_006611.1|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR015033(Region of unknown function DUF1916)|interpro:IPR027417|interpro:IPR037189|mint:Q9Y450|rcsb pdb:5LZW|rcsb pdb:5LZX|rcsb pdb:5LZY|rcsb pdb:5LZZ|reactome:R-HSA-429958|ensembl:ENSG00000112339(gene)|ensembl:ENST00000367837(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel) - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZyFFgoy7HM3oZ35I16XAH3jCook9606 rogid:j93qk+f9rW1/Sem+tUzRay6UcKw9606 rigid:CLGIHQBQBZ132ObLsork5lvdm/Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQT5 uniprotkb:Q6Y7W6 intact:EBI-371866|uniprotkb:Q5QP85|uniprotkb:Q9Y3A8|ensembl:ENSP00000323046|uniprotkb:A8K0K6 intact:EBI-765394|uniprotkb:O75137|uniprotkb:Q7Z2Z8|uniprotkb:Q7Z3I2|uniprotkb:Q96HU4|uniprotkb:Q9NV82|uniprotkb:B9EG55|intact:EBI-10969943|uniprotkb:A6H8W4|uniprotkb:E9PBB0|ensembl:ENSP00000362664|ensembl:ENSP00000386537 psi-mi:exos3_human(display_long)|uniprotkb:EXOSC3(gene name)|psi-mi:EXOSC3(display_short)|uniprotkb:RRP40(gene name synonym)|uniprotkb:CGI-102(orf name)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:p10(gene name synonym) psi-mi:ggyf2_human(display_long)|uniprotkb:Trinucleotide repeat-containing gene 15 protein(gene name synonym)|uniprotkb:GIGYF2(gene name)|psi-mi:GIGYF2(display_short)|uniprotkb:KIAA0642(gene name synonym)|uniprotkb:TNRC15(gene name synonym)|uniprotkb:PERQ2(gene name synonym)|uniprotkb:PERQ amino acid-rich with GYF domain-containing protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478433|imex:IM-26985-539 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001002269.1|refseq:NP_057126.2|ensembl:ENSG00000107371(gene)|ensembl:ENST00000327304(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q9NQT5|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29847N refseq:NP_001096616.1|refseq:NP_056390.2|refseq:NP_001096617.1|refseq:NP_001096618.1|ensembl:ENSG00000204120(gene)|ensembl:ENST00000373563(transcript)|ensembl:ENST00000409547(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007631"(feeding behavior)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043204"(perikaryon)|go:"GO:0044267"(cellular protein metabolic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050881"(musculoskeletal movement)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0070064"(proline-rich region binding)|go:"GO:1990635"(proximal dendrite)|interpro:IPR003169(GYF)|interpro:IPR035445|rcsb pdb:5NVL|rcsb pdb:5NVM|mint:Q6Y7W6 - - comment:"author score: 36" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZyFFgoy7HM3oZ35I16XAH3jCook9606 rogid:LCnAT/BvynGfhb1p3KMftXk8S3Q9606 rigid:CLGIHQBQBZ132ObLsork5lvdm/Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQT5 uniprotkb:O60573 intact:EBI-371866|uniprotkb:Q5QP85|uniprotkb:Q9Y3A8|ensembl:ENSP00000323046|uniprotkb:A8K0K6 intact:EBI-398610|uniprotkb:O75349|uniprotkb:B8ZZJ9|ensembl:ENSP00000258416 psi-mi:exos3_human(display_long)|uniprotkb:EXOSC3(gene name)|psi-mi:EXOSC3(display_short)|uniprotkb:RRP40(gene name synonym)|uniprotkb:CGI-102(orf name)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:p10(gene name synonym) psi-mi:if4e2_human(display_long)|uniprotkb:EIF4E2(gene name)|psi-mi:EIF4E2(display_short)|uniprotkb:mRNA cap-binding protein type 3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4E-like 3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4E homologous protein(gene name synonym)|uniprotkb:mRNA cap-binding protein 4EHP(gene name synonym)|uniprotkb:eIF4E-like protein 4E-LP(gene name synonym)|uniprotkb:EIF4EL3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478433|imex:IM-26985-539 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001002269.1|refseq:NP_057126.2|ensembl:ENSG00000107371(gene)|ensembl:ENST00000327304(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q9NQT5|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29847N refseq:NP_004837.1|dip:DIP-32578N|ensembl:ENSG00000135930(gene)|ensembl:ENST00000258416(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:O60573|rcsb pdb:2JGB|rcsb pdb:2JGC|rcsb pdb:5NVK|rcsb pdb:5NVL|rcsb pdb:5NVM|rcsb pdb:5NVN|rcsb pdb:5XLN|reactome:R-HSA-1169408|refseq:NP_001263265.1 - - comment:"author score: 41" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZyFFgoy7HM3oZ35I16XAH3jCook9606 rogid:fjre85PBJjEPNVrWjFUUX5NeuEE9606 rigid:CLGIHQBQBZ132ObLsork5lvdm/Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQT5 uniprotkb:Q6NZY4 intact:EBI-371866|uniprotkb:Q5QP85|uniprotkb:Q9Y3A8|ensembl:ENSP00000323046|uniprotkb:A8K0K6 intact:EBI-1263058|uniprotkb:Q7L2P6|uniprotkb:Q8N2K5|uniprotkb:Q96SK7|uniprotkb:Q9NSS2|uniprotkb:Q9NSS3|ensembl:ENSP00000488055|ensembl:ENSP00000500728 psi-mi:exos3_human(display_long)|uniprotkb:EXOSC3(gene name)|psi-mi:EXOSC3(display_short)|uniprotkb:RRP40(gene name synonym)|uniprotkb:CGI-102(orf name)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:p10(gene name synonym) psi-mi:zchc8_human(display_long)|uniprotkb:ZCCHC8(gene name)|psi-mi:ZCCHC8(display_short)|uniprotkb:TRAMP-like complex RNA-binding factor ZCCHC8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478433|imex:IM-26985-539 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001002269.1|refseq:NP_057126.2|ensembl:ENSG00000107371(gene)|ensembl:ENST00000327304(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q9NQT5|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29847N refseq:NP_060082.2|ensembl:ENSG00000033030(gene)|ensembl:ENST00000633063(transcript)|ensembl:ENST00000672018(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016076"(snRNA catabolic process)|go:"GO:0016604"(nuclear body)|go:"GO:0031499"(TRAMP complex)|go:"GO:0034470"(ncRNA processing)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR006568(PSP, proline-rich)|mint:Q6NZY4|rcsb pdb:5LXR|rcsb pdb:5LXY|rcsb pdb:6C90 - - comment:"author score: 45" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZyFFgoy7HM3oZ35I16XAH3jCook9606 rogid:dtjoaLAUgEGavPmqaJLPnLPHLP49606 rigid:CLGIHQBQBZ132ObLsork5lvdm/Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQT5 uniprotkb:P42285 intact:EBI-371866|uniprotkb:Q5QP85|uniprotkb:Q9Y3A8|ensembl:ENSP00000323046|uniprotkb:A8K0K6 intact:EBI-347612|uniprotkb:Q2M386|uniprotkb:Q6MZZ8|uniprotkb:Q6P170|uniprotkb:Q8N5R0|uniprotkb:Q8TAG2|ensembl:ENSP00000230640 psi-mi:exos3_human(display_long)|uniprotkb:EXOSC3(gene name)|psi-mi:EXOSC3(display_short)|uniprotkb:RRP40(gene name synonym)|uniprotkb:CGI-102(orf name)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:p10(gene name synonym) psi-mi:mtrex_human(display_long)|uniprotkb:MTREX(gene name)|psi-mi:MTREX(display_short)|uniprotkb:DOB1(gene name synonym)|uniprotkb:KIAA0052(gene name synonym)|uniprotkb:MTR4(gene name synonym)|uniprotkb:SKIV2L2(gene name synonym)|uniprotkb:Superkiller viralicidic activity 2-like 2(gene name synonym)|uniprotkb:TRAMP-like complex helicase(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DOB1(gene name synonym)|uniprotkb:ATP-dependent RNA helicase SKIV2L2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478433|imex:IM-26985-539 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001002269.1|refseq:NP_057126.2|ensembl:ENSG00000107371(gene)|ensembl:ENST00000327304(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q9NQT5|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29847N refseq:NP_056175.3|ensembl:ENSG00000039123(gene)|ensembl:ENST00000230640(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016076"(snRNA catabolic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0031499"(TRAMP complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012961(DSH, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016438(RNA helicase, ATP-dependent, SK12/DOB1)|interpro:IPR025696|interpro:IPR027417|mint:P42285|rcsb pdb:6C90|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6IEG|rcsb pdb:6IEH|rcsb pdb:6RO1|reactome:R-HSA-6791226|reactome:R-HSA-72163 - - comment:"author score: 121" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZyFFgoy7HM3oZ35I16XAH3jCook9606 rogid:bQdFDddFhetSp+CJ1S7Q5cm+g0k9606 rigid:CLGIHQBQBZ132ObLsork5lvdm/Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQT5 uniprotkb:P52888 intact:EBI-371866|uniprotkb:Q5QP85|uniprotkb:Q9Y3A8|ensembl:ENSP00000323046|uniprotkb:A8K0K6 intact:EBI-372399|uniprotkb:B3KSE2|uniprotkb:Q9UCB3|ensembl:ENSP00000304467 psi-mi:exos3_human(display_long)|uniprotkb:EXOSC3(gene name)|psi-mi:EXOSC3(display_short)|uniprotkb:RRP40(gene name synonym)|uniprotkb:CGI-102(orf name)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:p10(gene name synonym) psi-mi:thop1_human(display_long)|uniprotkb:Endopeptidase 24.15(gene name synonym)|uniprotkb:MP78(gene name synonym)|uniprotkb:THOP1(gene name)|psi-mi:THOP1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478433|imex:IM-26985-539 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001002269.1|refseq:NP_057126.2|ensembl:ENSG00000107371(gene)|ensembl:ENST00000327304(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q9NQT5|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29847N refseq:NP_003240.1|ensembl:ENSG00000172009(gene)|ensembl:ENST00000307741(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006518"(peptide metabolic process)|go:"GO:0042277"(peptide binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR001567(Peptidase M3A and M3B, thimet/oligopeptidase F)|interpro:IPR024077|interpro:IPR024079|interpro:IPR024080|mint:P52888|rcsb pdb:1S4B|rcsb pdb:2O36|reactome:R-HSA-983168 - - comment:"author score: 133" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZyFFgoy7HM3oZ35I16XAH3jCook9606 rogid:EAAq3MBfginBVCvaZWRI2dLiq2g9606 rigid:CLGIHQBQBZ132ObLsork5lvdm/Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQT5 uniprotkb:Q99547 intact:EBI-371866|uniprotkb:Q5QP85|uniprotkb:Q9Y3A8|ensembl:ENSP00000323046|uniprotkb:A8K0K6 intact:EBI-373187|uniprotkb:B2RAF0|ensembl:ENSP00000258169 psi-mi:exos3_human(display_long)|uniprotkb:EXOSC3(gene name)|psi-mi:EXOSC3(display_short)|uniprotkb:RRP40(gene name synonym)|uniprotkb:CGI-102(orf name)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:p10(gene name synonym) psi-mi:mph6_human(display_long)|uniprotkb:MPHOSPH6(gene name)|psi-mi:MPHOSPH6(display_short)|uniprotkb:MPP6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478433|imex:IM-26985-539 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001002269.1|refseq:NP_057126.2|ensembl:ENSG00000107371(gene)|ensembl:ENST00000327304(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q9NQT5|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29847N refseq:NP_005783.2|ensembl:ENSG00000135698(gene)|ensembl:ENST00000258169(transcript)|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|interpro:IPR019324|mint:Q99547|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-6791226|dip:DIP-31131N - - comment:"author score: 139" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZyFFgoy7HM3oZ35I16XAH3jCook9606 rogid:B53KiT1Bo6QC3Ckmf28PoKlRRms9606 rigid:CLGIHQBQBZ132ObLsork5lvdm/Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQT5 uniprotkb:Q06265 intact:EBI-371866|uniprotkb:Q5QP85|uniprotkb:Q9Y3A8|ensembl:ENSP00000323046|uniprotkb:A8K0K6 intact:EBI-347966|ensembl:ENSP00000243498|uniprotkb:Q12883|uniprotkb:Q86Y41|uniprotkb:Q86Y48|uniprotkb:Q4W5P5 psi-mi:exos3_human(display_long)|uniprotkb:EXOSC3(gene name)|psi-mi:EXOSC3(display_short)|uniprotkb:RRP40(gene name synonym)|uniprotkb:CGI-102(orf name)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:p10(gene name synonym) psi-mi:exos9_human(display_long)|uniprotkb:EXOSC9(gene name)|psi-mi:EXOSC9(display_short)|uniprotkb:PMSCL1(gene name synonym)|uniprotkb:Exosome component 9(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 1(gene name synonym)|uniprotkb:Autoantigen PM/Scl 1(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 75 kDa(gene name synonym)|uniprotkb:P75 polymyositis-scleroderma overlap syndrome-associated autoantigen(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478433|imex:IM-26985-539 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001002269.1|refseq:NP_057126.2|ensembl:ENSG00000107371(gene)|ensembl:ENST00000327304(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q9NQT5|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29847N go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006955"(immune response)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033100|interpro:IPR036345|mint:Q06265|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|ensembl:ENSG00000123737(gene)|ensembl:ENST00000243498(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|refseq:NP_001029366.1|refseq:NP_005024.2|dip:DIP-31286N - - comment:"author score: 174" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZyFFgoy7HM3oZ35I16XAH3jCook9606 rogid:COzGZISdlfGlht1FhyxPhzbV9hY9606 rigid:CLGIHQBQBZ132ObLsork5lvdm/Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQT5 uniprotkb:Q5RKV6 intact:EBI-371866|uniprotkb:Q5QP85|uniprotkb:Q9Y3A8|ensembl:ENSP00000323046|uniprotkb:A8K0K6 intact:EBI-2841747|ensembl:ENSP00000398597 psi-mi:exos3_human(display_long)|uniprotkb:EXOSC3(gene name)|psi-mi:EXOSC3(display_short)|uniprotkb:RRP40(gene name synonym)|uniprotkb:CGI-102(orf name)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:p10(gene name synonym) psi-mi:exos6_human(display_long)|uniprotkb:EXOSC6(gene name)|psi-mi:EXOSC6(display_short)|uniprotkb:MTR3(gene name synonym)|uniprotkb:Exosome component 6(gene name synonym)|uniprotkb:mRNA transport regulator 3 homolog(gene name synonym)|uniprotkb:p11(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478433|imex:IM-26985-539 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001002269.1|refseq:NP_057126.2|ensembl:ENSG00000107371(gene)|ensembl:ENST00000327304(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q9NQT5|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29847N refseq:NP_478126.1|ensembl:ENSG00000223496(gene)|ensembl:ENST00000435634(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q5RKV6|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-61038N - - comment:"author score: 179" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZyFFgoy7HM3oZ35I16XAH3jCook9606 rogid:tHH05GXmmH4GgRjtChjaGSLJ7Cc9606 rigid:CLGIHQBQBZ132ObLsork5lvdm/Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQT5 uniprotkb:Q9Y3B2 intact:EBI-371866|uniprotkb:Q5QP85|uniprotkb:Q9Y3A8|ensembl:ENSP00000323046|uniprotkb:A8K0K6 intact:EBI-371892|uniprotkb:Q5JTH3|uniprotkb:B2R9B3|ensembl:ENSP00000359939 psi-mi:exos3_human(display_long)|uniprotkb:EXOSC3(gene name)|psi-mi:EXOSC3(display_short)|uniprotkb:RRP40(gene name synonym)|uniprotkb:CGI-102(orf name)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:p10(gene name synonym) psi-mi:exos1_human(display_long)|uniprotkb:CSL4(gene name synonym)|uniprotkb:EXOSC1(gene name)|psi-mi:EXOSC1(display_short)|uniprotkb:CGI-108(orf name)|uniprotkb:Exosome component 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478433|imex:IM-26985-539 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001002269.1|refseq:NP_057126.2|ensembl:ENSG00000107371(gene)|ensembl:ENST00000327304(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q9NQT5|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29847N refseq:NP_057130.1|refseq:NP_001305291.1|refseq:NP_001305292.1|refseq:NP_001305293.1|refseq:NP_001305294.1|refseq:NP_001305295.1|ensembl:ENSG00000171311(gene)|ensembl:ENST00000370902(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR022967|interpro:IPR025721|interpro:IPR039771|mint:Q9Y3B2|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31261N - - comment:"author score: 184" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZyFFgoy7HM3oZ35I16XAH3jCook9606 rogid:IBOBnAbHLduWe+40D2nLS1itYhY9606 rigid:CLGIHQBQBZ132ObLsork5lvdm/Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQT5 uniprotkb:Q15024 intact:EBI-371866|uniprotkb:Q5QP85|uniprotkb:Q9Y3A8|ensembl:ENSP00000323046|uniprotkb:A8K0K6 intact:EBI-371841|uniprotkb:Q96E72|ensembl:ENSP00000265564 psi-mi:exos3_human(display_long)|uniprotkb:EXOSC3(gene name)|psi-mi:EXOSC3(display_short)|uniprotkb:RRP40(gene name synonym)|uniprotkb:CGI-102(orf name)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:p10(gene name synonym) psi-mi:exos7_human(display_long)|uniprotkb:KIAA0116(gene name synonym)|uniprotkb:RRP42(gene name synonym)|uniprotkb:EXOSC7(gene name)|psi-mi:EXOSC7(display_short)|uniprotkb:Ribosomal RNA-processing protein 42(gene name synonym)|uniprotkb:Exosome component 7(gene name synonym)|uniprotkb:p8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478433|imex:IM-26985-539 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001002269.1|refseq:NP_057126.2|ensembl:ENSG00000107371(gene)|ensembl:ENST00000327304(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q9NQT5|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29847N refseq:NP_055819.2|ensembl:ENSG00000075914(gene)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|ensembl:ENST00000265564(transcript)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q15024|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|go:"GO:0034475"(U4 snRNA 3'-end processing)|dip:DIP-31266N - - comment:"author score: 220" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZyFFgoy7HM3oZ35I16XAH3jCook9606 rogid:gFGj7nvYM3a56Pu7vryrP+XfUxE9606 rigid:CLGIHQBQBZ132ObLsork5lvdm/Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQT5 uniprotkb:Q96B26 intact:EBI-371866|uniprotkb:Q5QP85|uniprotkb:Q9Y3A8|ensembl:ENSP00000323046|uniprotkb:A8K0K6 intact:EBI-371922|uniprotkb:O43480|uniprotkb:Q5TBA5|ensembl:ENSP00000374354 psi-mi:exos3_human(display_long)|uniprotkb:EXOSC3(gene name)|psi-mi:EXOSC3(display_short)|uniprotkb:RRP40(gene name synonym)|uniprotkb:CGI-102(orf name)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:p10(gene name synonym) psi-mi:exos8_human(display_long)|uniprotkb:OIP2(gene name synonym)|uniprotkb:RRP43(gene name synonym)|uniprotkb:EXOSC8(gene name)|psi-mi:EXOSC8(display_short)|uniprotkb:Ribosomal RNA-processing protein 43(gene name synonym)|uniprotkb:Exosome component 8(gene name synonym)|uniprotkb:p9(gene name synonym)|uniprotkb:Opa-interacting protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478433|imex:IM-26985-539 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001002269.1|refseq:NP_057126.2|ensembl:ENSG00000107371(gene)|ensembl:ENST00000327304(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q9NQT5|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29847N refseq:NP_852480.1|ensembl:ENSG00000120699(gene)|ensembl:ENST00000389704(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033196|go:"GO:0005829"(cytosol)|mint:Q96B26|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|interpro:IPR036345|dip:DIP-31133N - - comment:"author score: 222" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZyFFgoy7HM3oZ35I16XAH3jCook9606 rogid:y/cReHiPMubzNruyETohBjbRick9606 rigid:CLGIHQBQBZ132ObLsork5lvdm/Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQT5 uniprotkb:Q01780 intact:EBI-371866|uniprotkb:Q5QP85|uniprotkb:Q9Y3A8|ensembl:ENSP00000323046|uniprotkb:A8K0K6 intact:EBI-358236|uniprotkb:B1AKQ1|uniprotkb:Q15158|uniprotkb:B1AKQ0|intact:EBI-28973393|ensembl:ENSP00000366135 psi-mi:exos3_human(display_long)|uniprotkb:EXOSC3(gene name)|psi-mi:EXOSC3(display_short)|uniprotkb:RRP40(gene name synonym)|uniprotkb:CGI-102(orf name)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:p10(gene name synonym) psi-mi:exosx_human(display_long)|uniprotkb:PMSCL2(gene name synonym)|uniprotkb:EXOSC10(gene name)|psi-mi:EXOSC10(display_short)|uniprotkb:PMSCL(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 2(gene name synonym)|uniprotkb:Autoantigen PM/Scl 2(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 100 kDa(gene name synonym)|uniprotkb:P100 polymyositis-scleroderma overlap syndrome-associated autoantigen(gene name synonym)|uniprotkb:RRP6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478433|imex:IM-26985-539 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001002269.1|refseq:NP_057126.2|ensembl:ENSG00000107371(gene)|ensembl:ENST00000327304(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q9NQT5|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29847N ensembl:ENST00000304457|ensembl:ENSP00000307307|ensembl:ENSP00000366135|refseq:NP_001001998.1|refseq:NP_002676.1|dip:DIP-31249N|ensembl:ENSG00000171824(gene)|ensembl:ENST00000376936(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071048"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|go:"GO:0016020"(membrane)|interpro:IPR010997(HRDC-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012588(Exosome-associated factor Rrp6, N-terminal)|interpro:IPR036397|mint:Q01780|rcsb pdb:2CPR|rcsb pdb:3SAF|rcsb pdb:3SAG|rcsb pdb:3SAH|rcsb pdb:6D6Q|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0035327"|rcsb pdb:6D6R|reactome:R-HSA-6791226|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process) - - comment:"author score: 242" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZyFFgoy7HM3oZ35I16XAH3jCook9606 rogid:JeBuVE3nYxlFwYt/xUGlIC6ANJo9606 rigid:CLGIHQBQBZ132ObLsork5lvdm/Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQT5 uniprotkb:Q13868 intact:EBI-371866|uniprotkb:Q5QP85|uniprotkb:Q9Y3A8|ensembl:ENSP00000323046|uniprotkb:A8K0K6 intact:EBI-301735|uniprotkb:Q9NUY4|uniprotkb:A3KFL3|ensembl:ENSP00000361433|uniprotkb:A3KFL4|uniprotkb:B4DKK6 psi-mi:exos3_human(display_long)|uniprotkb:EXOSC3(gene name)|psi-mi:EXOSC3(display_short)|uniprotkb:RRP40(gene name synonym)|uniprotkb:CGI-102(orf name)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:p10(gene name synonym) psi-mi:exos2_human(display_long)|uniprotkb:EXOSC2(gene name)|psi-mi:EXOSC2(display_short)|uniprotkb:RRP4(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 4(gene name synonym)|uniprotkb:Exosome component 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478433|imex:IM-26985-539 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001002269.1|refseq:NP_057126.2|ensembl:ENSG00000107371(gene)|ensembl:ENST00000327304(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q9NQT5|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29847N refseq:NP_055100.2|ensembl:ENSG00000130713(gene)|ensembl:ENST00000372358(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR025721|interpro:IPR026699|interpro:IPR036612|mint:Q13868|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|refseq:NP_001269638.1|dip:DIP-31264N|refseq:NP_001269637.1 - - comment:"author score: 266" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZyFFgoy7HM3oZ35I16XAH3jCook9606 rogid:Lpl4OBbEYV2DRbYzLCPvbQdtaro9606 rigid:CLGIHQBQBZ132ObLsork5lvdm/Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P06730 uniprotkb:P60842 intact:EBI-73440|uniprotkb:Q96E95|ensembl:ENSP00000389624|uniprotkb:D6RCQ6|uniprotkb:B7Z6V1|intact:EBI-28969298 intact:EBI-73449|uniprotkb:P04765|uniprotkb:Q5U018|uniprotkb:Q61516|uniprotkb:B2R6L8|uniprotkb:D3DTP9|uniprotkb:J3QLC4|ensembl:ENSP00000293831 psi-mi:if4e_human(display_long)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:EIF4E(gene name)|psi-mi:EIF4E(display_short)|uniprotkb:EIF4EL1(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:if4a1_human(display_long)|uniprotkb:EIF4A1(gene name)|psi-mi:EIF4A1(display_short)|uniprotkb:EIF4A(gene name synonym)|uniprotkb:DDX2A(gene name synonym)|uniprotkb:ATP-dependent RNA helicase eIF4A-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478272|imex:IM-26985-321 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124151.1|refseq:NP_001959.1|ensembl:ENST00000280892|ensembl:ENSP00000280892|ensembl:ENSP00000389624|ensembl:ENST00000505992|ensembl:ENSP00000425561|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:2W97|rcsb pdb:3AM7|rcsb pdb:3TF2|rcsb pdb:3U7X|rcsb pdb:4AZA|rcsb pdb:4BEA|rcsb pdb:4DT6|rcsb pdb:4DUM|rcsb pdb:4TPW|rcsb pdb:4TQB|rcsb pdb:4TQC|rcsb pdb:4UED|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5EKV|rcsb pdb:5GW6|rcsb pdb:5T46|rcsb pdb:5ZJY|rcsb pdb:5ZJZ|rcsb pdb:5ZK5|rcsb pdb:5ZK7|rcsb pdb:5ZK9|ensembl:ENSG00000151247(gene)|rcsb pdb:5ZML|rcsb pdb:7MEU|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-159231|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-159230|reactome:R-HSA-159227|ensembl:ENST00000450253(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:P06730|rcsb pdb:1IPB|rcsb pdb:1IPC|rcsb pdb:1WKW|rcsb pdb:2GPQ|rcsb pdb:2V8W|refseq:NP_001124150.1|refseq:NP_001317946.1|dip:DIP-22N refseq:NP_001407.1|refseq:NP_001191439.1|dip:DIP-29755N|ensembl:ENSG00000161960(gene)|ensembl:ENST00000293831(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016020"(membrane)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|mint:P60842|rcsb pdb:2G9N|rcsb pdb:2ZU6|rcsb pdb:3EIQ|rcsb pdb:5ZBZ|rcsb pdb:5ZC9|rcsb pdb:6ZMW|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:9173bxjOdBfKj36pWVvzw7M6g1A9606 rogid:e+2gp47oHrpxFbrBFSM4qTf3r7E9606 rigid:K7Tc/kS/KJThP9549IijRxXlcys false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P06730 uniprotkb:O00303 intact:EBI-73440|uniprotkb:Q96E95|ensembl:ENSP00000389624|uniprotkb:D6RCQ6|uniprotkb:B7Z6V1|intact:EBI-28969298 intact:EBI-711990|ensembl:ENSP00000431800|ensembl:ENSP00000499218|uniprotkb:Q6IB45|uniprotkb:Q8N978|uniprotkb:A8K0S2 psi-mi:if4e_human(display_long)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:EIF4E(gene name)|psi-mi:EIF4E(display_short)|uniprotkb:EIF4EL1(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:eif3f_human(display_long)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 5(gene name synonym)|uniprotkb:eIF-3-epsilon(gene name synonym)|uniprotkb:eIF3 p47(gene name synonym)|uniprotkb:EIF3F(gene name)|psi-mi:EIF3F(display_short)|uniprotkb:EIF3S5(gene name synonym)|uniprotkb:Deubiquitinating enzyme eIF3f(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478272|imex:IM-26985-321 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124151.1|refseq:NP_001959.1|ensembl:ENST00000280892|ensembl:ENSP00000280892|ensembl:ENSP00000389624|ensembl:ENST00000505992|ensembl:ENSP00000425561|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:2W97|rcsb pdb:3AM7|rcsb pdb:3TF2|rcsb pdb:3U7X|rcsb pdb:4AZA|rcsb pdb:4BEA|rcsb pdb:4DT6|rcsb pdb:4DUM|rcsb pdb:4TPW|rcsb pdb:4TQB|rcsb pdb:4TQC|rcsb pdb:4UED|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5EKV|rcsb pdb:5GW6|rcsb pdb:5T46|rcsb pdb:5ZJY|rcsb pdb:5ZJZ|rcsb pdb:5ZK5|rcsb pdb:5ZK7|rcsb pdb:5ZK9|ensembl:ENSG00000151247(gene)|rcsb pdb:5ZML|rcsb pdb:7MEU|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-159231|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-159230|reactome:R-HSA-159227|ensembl:ENST00000450253(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:P06730|rcsb pdb:1IPB|rcsb pdb:1IPC|rcsb pdb:1WKW|rcsb pdb:2GPQ|rcsb pdb:2V8W|refseq:NP_001124150.1|refseq:NP_001317946.1|dip:DIP-22N ensembl:ENSG00000175390(gene)|ensembl:ENST00000533626(transcript)|ensembl:ENST00000651655(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0101005"(deubiquitinase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR024969|interpro:IPR027531|interpro:IPR037518|mint:O00303|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_003745.1|dip:DIP-35580N - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:9173bxjOdBfKj36pWVvzw7M6g1A9606 rogid:dpH1pTcPshcrSjNCdPPnkYiW0YU9606 rigid:K7Tc/kS/KJThP9549IijRxXlcys false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P06730 uniprotkb:P60228 intact:EBI-73440|uniprotkb:Q96E95|ensembl:ENSP00000389624|uniprotkb:D6RCQ6|uniprotkb:B7Z6V1|intact:EBI-28969298 intact:EBI-347740|uniprotkb:O43902|uniprotkb:Q64058|uniprotkb:Q64059|uniprotkb:Q64252|uniprotkb:Q8WVK4|intact:EBI-1237448|uniprotkb:Q6FG33|ensembl:ENSP00000220849 psi-mi:if4e_human(display_long)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:EIF4E(gene name)|psi-mi:EIF4E(display_short)|uniprotkb:EIF4EL1(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:eif3e_human(display_long)|uniprotkb:EIF3E(gene name)|psi-mi:EIF3E(display_short)|uniprotkb:INT6(gene name synonym)|uniprotkb:EIF3S6(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 6(gene name synonym)|uniprotkb:eIF-3 p48(gene name synonym)|uniprotkb:Viral integration site protein INT-6 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478272|imex:IM-26985-321 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124151.1|refseq:NP_001959.1|ensembl:ENST00000280892|ensembl:ENSP00000280892|ensembl:ENSP00000389624|ensembl:ENST00000505992|ensembl:ENSP00000425561|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:2W97|rcsb pdb:3AM7|rcsb pdb:3TF2|rcsb pdb:3U7X|rcsb pdb:4AZA|rcsb pdb:4BEA|rcsb pdb:4DT6|rcsb pdb:4DUM|rcsb pdb:4TPW|rcsb pdb:4TQB|rcsb pdb:4TQC|rcsb pdb:4UED|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5EKV|rcsb pdb:5GW6|rcsb pdb:5T46|rcsb pdb:5ZJY|rcsb pdb:5ZJZ|rcsb pdb:5ZK5|rcsb pdb:5ZK7|rcsb pdb:5ZK9|ensembl:ENSG00000151247(gene)|rcsb pdb:5ZML|rcsb pdb:7MEU|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-159231|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-159230|reactome:R-HSA-159227|ensembl:ENST00000450253(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:P06730|rcsb pdb:1IPB|rcsb pdb:1IPC|rcsb pdb:1WKW|rcsb pdb:2GPQ|rcsb pdb:2V8W|refseq:NP_001124150.1|refseq:NP_001317946.1|dip:DIP-22N refseq:NP_001559.1|ensembl:ENSG00000104408(gene)|ensembl:ENST00000220849(transcript)|dip:DIP-32691N|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0016605"(PML body)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071540"(eukaryotic translation initiation factor 3 complex, eIF3e)|go:"GO:1902416"(positive regulation of mRNA binding)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR016650(Translation initiation factor 3, subunit 6, eukaryotic)|interpro:IPR019010|interpro:IPR036390|mint:P60228|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6FEC|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706 - - comment:"author score: 27" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:9173bxjOdBfKj36pWVvzw7M6g1A9606 rogid:s09LicCa0mb9WwO7esZvVdvUonY9606 rigid:K7Tc/kS/KJThP9549IijRxXlcys false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P06730 uniprotkb:Q7L2H7 intact:EBI-73440|uniprotkb:Q96E95|ensembl:ENSP00000389624|uniprotkb:D6RCQ6|uniprotkb:B7Z6V1|intact:EBI-28969298 intact:EBI-353901|intact:EBI-4289539|intact:EBI-715219|uniprotkb:Q2F836|uniprotkb:Q53HL6|uniprotkb:Q9BXW1|uniprotkb:O60735|uniprotkb:A8K7X4|intact:EBI-2559366|ensembl:ENSP00000436049|intact:EBI-373200|uniprotkb:B4E2Q4 psi-mi:if4e_human(display_long)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:EIF4E(gene name)|psi-mi:EIF4E(display_short)|uniprotkb:EIF4EL1(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:eif3m_human(display_long)|uniprotkb:EIF3M(gene name)|psi-mi:EIF3M(display_short)|uniprotkb:HFLB5(gene name synonym)|uniprotkb:PCID1(gene name synonym)|uniprotkb:PCI domain-containing protein 1(gene name synonym)|uniprotkb:Fetal lung protein B5(gene name synonym)|uniprotkb:GA17(orf name)|uniprotkb:PNAS-125(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478272|imex:IM-26985-321 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124151.1|refseq:NP_001959.1|ensembl:ENST00000280892|ensembl:ENSP00000280892|ensembl:ENSP00000389624|ensembl:ENST00000505992|ensembl:ENSP00000425561|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:2W97|rcsb pdb:3AM7|rcsb pdb:3TF2|rcsb pdb:3U7X|rcsb pdb:4AZA|rcsb pdb:4BEA|rcsb pdb:4DT6|rcsb pdb:4DUM|rcsb pdb:4TPW|rcsb pdb:4TQB|rcsb pdb:4TQC|rcsb pdb:4UED|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5EKV|rcsb pdb:5GW6|rcsb pdb:5T46|rcsb pdb:5ZJY|rcsb pdb:5ZJZ|rcsb pdb:5ZK5|rcsb pdb:5ZK7|rcsb pdb:5ZK9|ensembl:ENSG00000151247(gene)|rcsb pdb:5ZML|rcsb pdb:7MEU|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-159231|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-159230|reactome:R-HSA-159227|ensembl:ENST00000450253(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:P06730|rcsb pdb:1IPB|rcsb pdb:1IPC|rcsb pdb:1WKW|rcsb pdb:2GPQ|rcsb pdb:2V8W|refseq:NP_001124150.1|refseq:NP_001317946.1|dip:DIP-22N refseq:NP_006351.2|refseq:NP_001294858.1|ensembl:ENSG00000149100(gene)|ensembl:ENST00000531120(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027528|interpro:IPR036390|interpro:IPR040750|mint:Q7L2H7|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6FEC|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-31256N - - comment:"author score: 27" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:9173bxjOdBfKj36pWVvzw7M6g1A9606 rogid:siTfTDezqWL90pw6xG3xUKfY9n49606 rigid:K7Tc/kS/KJThP9549IijRxXlcys false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P06730 uniprotkb:Q71UM5 intact:EBI-73440|uniprotkb:Q96E95|ensembl:ENSP00000389624|uniprotkb:D6RCQ6|uniprotkb:B7Z6V1|intact:EBI-28969298 intact:EBI-355126|uniprotkb:Q9BTJ1|ensembl:ENSP00000331019 psi-mi:if4e_human(display_long)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:EIF4E(gene name)|psi-mi:EIF4E(display_short)|uniprotkb:EIF4EL1(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:rs27l_human(display_long)|uniprotkb:RPS27L(gene name)|psi-mi:RPS27L(display_short)|uniprotkb:Small ribosomal subunit protein eS27-like(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478272|imex:IM-26985-321 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124151.1|refseq:NP_001959.1|ensembl:ENST00000280892|ensembl:ENSP00000280892|ensembl:ENSP00000389624|ensembl:ENST00000505992|ensembl:ENSP00000425561|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:2W97|rcsb pdb:3AM7|rcsb pdb:3TF2|rcsb pdb:3U7X|rcsb pdb:4AZA|rcsb pdb:4BEA|rcsb pdb:4DT6|rcsb pdb:4DUM|rcsb pdb:4TPW|rcsb pdb:4TQB|rcsb pdb:4TQC|rcsb pdb:4UED|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5EKV|rcsb pdb:5GW6|rcsb pdb:5T46|rcsb pdb:5ZJY|rcsb pdb:5ZJZ|rcsb pdb:5ZK5|rcsb pdb:5ZK7|rcsb pdb:5ZK9|ensembl:ENSG00000151247(gene)|rcsb pdb:5ZML|rcsb pdb:7MEU|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-159231|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-159230|reactome:R-HSA-159227|ensembl:ENST00000450253(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:P06730|rcsb pdb:1IPB|rcsb pdb:1IPC|rcsb pdb:1WKW|rcsb pdb:2GPQ|rcsb pdb:2V8W|refseq:NP_001124150.1|refseq:NP_001317946.1|dip:DIP-22N refseq:NP_057004.1|ensembl:ENSG00000185088(gene)|ensembl:ENST00000330964(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0006412"(translation)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008494"(translation activator activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046872"(metal ion binding)|interpro:IPR000592(Ribosomal protein S27e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR023407|mint:Q71UM5|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - comment:"author score: 28" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:9173bxjOdBfKj36pWVvzw7M6g1A9606 rogid:OVIAlDF6dN3DxLZgQFrFl8r0Z0I9606 rigid:K7Tc/kS/KJThP9549IijRxXlcys false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P06730 uniprotkb:Q14152 intact:EBI-73440|uniprotkb:Q96E95|ensembl:ENSP00000389624|uniprotkb:D6RCQ6|uniprotkb:B7Z6V1|intact:EBI-28969298 intact:EBI-366617|uniprotkb:O00653|uniprotkb:Q15778|uniprotkb:B1AMV5|intact:EBI-28978176|ensembl:ENSP00000358140|ensembl:ENSP00000438178|uniprotkb:B4DYS1|uniprotkb:F5H335 psi-mi:if4e_human(display_long)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:EIF4E(gene name)|psi-mi:EIF4E(display_short)|uniprotkb:EIF4EL1(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:eif3a_human(display_long)|uniprotkb:EIF3A(gene name)|psi-mi:EIF3A(display_short)|uniprotkb:KIAA0139(gene name synonym)|uniprotkb:EIF3S10(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 10(gene name synonym)|uniprotkb:eIF-3-theta(gene name synonym)|uniprotkb:eIF3 p167(gene name synonym)|uniprotkb:eIF3 p180(gene name synonym)|uniprotkb:eIF3 p185(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478272|imex:IM-26985-321 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124151.1|refseq:NP_001959.1|ensembl:ENST00000280892|ensembl:ENSP00000280892|ensembl:ENSP00000389624|ensembl:ENST00000505992|ensembl:ENSP00000425561|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:2W97|rcsb pdb:3AM7|rcsb pdb:3TF2|rcsb pdb:3U7X|rcsb pdb:4AZA|rcsb pdb:4BEA|rcsb pdb:4DT6|rcsb pdb:4DUM|rcsb pdb:4TPW|rcsb pdb:4TQB|rcsb pdb:4TQC|rcsb pdb:4UED|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5EKV|rcsb pdb:5GW6|rcsb pdb:5T46|rcsb pdb:5ZJY|rcsb pdb:5ZJZ|rcsb pdb:5ZK5|rcsb pdb:5ZK7|rcsb pdb:5ZK9|ensembl:ENSG00000151247(gene)|rcsb pdb:5ZML|rcsb pdb:7MEU|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-159231|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-159230|reactome:R-HSA-159227|ensembl:ENST00000450253(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:P06730|rcsb pdb:1IPB|rcsb pdb:1IPC|rcsb pdb:1WKW|rcsb pdb:2GPQ|rcsb pdb:2V8W|refseq:NP_001124150.1|refseq:NP_001317946.1|dip:DIP-22N refseq:NP_003741.1|ensembl:ENSP00000358140|ensembl:ENSP00000438178|ensembl:ENSG00000107581(gene)|ensembl:ENST00000369144(transcript)|ensembl:ENST00000541549(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002188"(translation reinitiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0005874"(microtubule)|go:"GO:0006413"(translational initiation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043614"(multi-eIF complex)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071540"(eukaryotic translation initiation factor 3 complex, eIF3e)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR027512|mint:Q14152|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6YBT|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-31114N - - comment:"author score: 34" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:9173bxjOdBfKj36pWVvzw7M6g1A9606 rogid:COyPBU7e0SUL3BiZY7NQuUkmxns9606 rigid:K7Tc/kS/KJThP9549IijRxXlcys false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P06730 uniprotkb:Q9UBQ5 intact:EBI-73440|uniprotkb:Q96E95|ensembl:ENSP00000389624|uniprotkb:D6RCQ6|uniprotkb:B7Z6V1|intact:EBI-28969298 intact:EBI-354344|uniprotkb:Q96IQ0|uniprotkb:Q9Y6D1|intact:EBI-2339187|uniprotkb:A8K0I9|ensembl:ENSP00000248342|ensembl:ENSP00000489438|uniprotkb:B7ZAM9 psi-mi:if4e_human(display_long)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:EIF4E(gene name)|psi-mi:EIF4E(display_short)|uniprotkb:EIF4EL1(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:eif3k_human(display_long)|uniprotkb:MSTP001(orf name)|uniprotkb:PTD001(orf name)|uniprotkb:HSPC029(orf name)|uniprotkb:EIF3K(gene name)|psi-mi:EIF3K(display_short)|uniprotkb:ARG134(orf name)|uniprotkb:EIF3S12(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 12(gene name synonym)|uniprotkb:eIF-3 p25(gene name synonym)|uniprotkb:eIF-3 p28(gene name synonym)|uniprotkb:Muscle-specific gene M9 protein(gene name synonym)|uniprotkb:PLAC-24(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478272|imex:IM-26985-321 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124151.1|refseq:NP_001959.1|ensembl:ENST00000280892|ensembl:ENSP00000280892|ensembl:ENSP00000389624|ensembl:ENST00000505992|ensembl:ENSP00000425561|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:2W97|rcsb pdb:3AM7|rcsb pdb:3TF2|rcsb pdb:3U7X|rcsb pdb:4AZA|rcsb pdb:4BEA|rcsb pdb:4DT6|rcsb pdb:4DUM|rcsb pdb:4TPW|rcsb pdb:4TQB|rcsb pdb:4TQC|rcsb pdb:4UED|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5EKV|rcsb pdb:5GW6|rcsb pdb:5T46|rcsb pdb:5ZJY|rcsb pdb:5ZJZ|rcsb pdb:5ZK5|rcsb pdb:5ZK7|rcsb pdb:5ZK9|ensembl:ENSG00000151247(gene)|rcsb pdb:5ZML|rcsb pdb:7MEU|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-159231|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-159230|reactome:R-HSA-159227|ensembl:ENST00000450253(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:P06730|rcsb pdb:1IPB|rcsb pdb:1IPC|rcsb pdb:1WKW|rcsb pdb:2GPQ|rcsb pdb:2V8W|refseq:NP_001124150.1|refseq:NP_001317946.1|dip:DIP-22N refseq:NP_037366.1|ensembl:ENSG00000282986(gene)|ensembl:ENST00000248342(transcript)|ensembl:ENST00000635567(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003743"(translation initiation factor activity)|ensembl:ENSG00000178982(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043022"(ribosome binding)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR009374(Translation initiation factor 3, subunit 12, eukaryotic)|interpro:IPR016020(Translation initiation factor 3, subunit 12, N-terminal, eukaryotic)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR033464|interpro:IPR036388|interpro:IPR036390|mint:Q9UBQ5|rcsb pdb:1RZ4|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6FEC|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-32880N - - comment:"author score: 35" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:9173bxjOdBfKj36pWVvzw7M6g1A9606 rogid:sle5eYxV0F37AzixzoNY4Jm6Loo9606 rigid:K7Tc/kS/KJThP9549IijRxXlcys false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P06730 uniprotkb:Q9UNK9 intact:EBI-73440|uniprotkb:Q96E95|ensembl:ENSP00000389624|uniprotkb:D6RCQ6|uniprotkb:B7Z6V1|intact:EBI-28969298 intact:EBI-12579907|ensembl:ENSP00000251089|uniprotkb:B4DWL7|uniprotkb:O94859|uniprotkb:Q8NCS9 psi-mi:if4e_human(display_long)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:EIF4E(gene name)|psi-mi:EIF4E(display_short)|uniprotkb:EIF4EL1(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:ange1_human(display_long)|uniprotkb:ANGEL1(gene name)|psi-mi:ANGEL1(display_short)|uniprotkb:KIAA0759(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478272|imex:IM-26985-321 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124151.1|refseq:NP_001959.1|ensembl:ENST00000280892|ensembl:ENSP00000280892|ensembl:ENSP00000389624|ensembl:ENST00000505992|ensembl:ENSP00000425561|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:2W97|rcsb pdb:3AM7|rcsb pdb:3TF2|rcsb pdb:3U7X|rcsb pdb:4AZA|rcsb pdb:4BEA|rcsb pdb:4DT6|rcsb pdb:4DUM|rcsb pdb:4TPW|rcsb pdb:4TQB|rcsb pdb:4TQC|rcsb pdb:4UED|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5EKV|rcsb pdb:5GW6|rcsb pdb:5T46|rcsb pdb:5ZJY|rcsb pdb:5ZJZ|rcsb pdb:5ZK5|rcsb pdb:5ZK7|rcsb pdb:5ZK9|ensembl:ENSG00000151247(gene)|rcsb pdb:5ZML|rcsb pdb:7MEU|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-159231|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-159230|reactome:R-HSA-159227|ensembl:ENST00000450253(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:P06730|rcsb pdb:1IPB|rcsb pdb:1IPC|rcsb pdb:1WKW|rcsb pdb:2GPQ|rcsb pdb:2V8W|refseq:NP_001124150.1|refseq:NP_001317946.1|dip:DIP-22N ensembl:ENSG00000013523(gene)|ensembl:ENST00000251089(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR036691|mint:Q9UNK9|refseq:NP_056120.2 - - comment:"author score: 35" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:9173bxjOdBfKj36pWVvzw7M6g1A9606 rogid:5WcU0CTNKN6ZYR5zg4oa1LuuAlE9606 rigid:K7Tc/kS/KJThP9549IijRxXlcys false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P06730 uniprotkb:Q99613 intact:EBI-73440|uniprotkb:Q96E95|ensembl:ENSP00000389624|uniprotkb:D6RCQ6|uniprotkb:B7Z6V1|intact:EBI-28969298 intact:EBI-353741|uniprotkb:A8K7Z0|intact:EBI-2876652|uniprotkb:O00215|uniprotkb:Q9BW98|uniprotkb:B2RXG3|intact:EBI-11017021|ensembl:ENSP00000332604|ensembl:ENSP00000378953|ensembl:ENSP00000457418|ensembl:ENSP00000457963|uniprotkb:B4E1D5|uniprotkb:H3BRV0 psi-mi:if4e_human(display_long)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:EIF4E(gene name)|psi-mi:EIF4E(display_short)|uniprotkb:EIF4EL1(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:eif3c_human(display_long)|uniprotkb:EIF3C(gene name)|psi-mi:EIF3C(display_short)|uniprotkb:EIF3S8(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 8(gene name synonym)|uniprotkb:eIF3 p110(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478272|imex:IM-26985-321 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124151.1|refseq:NP_001959.1|ensembl:ENST00000280892|ensembl:ENSP00000280892|ensembl:ENSP00000389624|ensembl:ENST00000505992|ensembl:ENSP00000425561|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:2W97|rcsb pdb:3AM7|rcsb pdb:3TF2|rcsb pdb:3U7X|rcsb pdb:4AZA|rcsb pdb:4BEA|rcsb pdb:4DT6|rcsb pdb:4DUM|rcsb pdb:4TPW|rcsb pdb:4TQB|rcsb pdb:4TQC|rcsb pdb:4UED|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5EKV|rcsb pdb:5GW6|rcsb pdb:5T46|rcsb pdb:5ZJY|rcsb pdb:5ZJZ|rcsb pdb:5ZK5|rcsb pdb:5ZK7|rcsb pdb:5ZK9|ensembl:ENSG00000151247(gene)|rcsb pdb:5ZML|rcsb pdb:7MEU|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-159231|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-159230|reactome:R-HSA-159227|ensembl:ENST00000450253(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:P06730|rcsb pdb:1IPB|rcsb pdb:1IPC|rcsb pdb:1WKW|rcsb pdb:2GPQ|rcsb pdb:2V8W|refseq:NP_001124150.1|refseq:NP_001317946.1|dip:DIP-22N refseq:NP_001032897.1|refseq:NP_001186071.1|refseq:NP_003743.1|refseq:NP_001273407.1|ensembl:ENSG00000184110(gene)|ensembl:ENST00000331666(transcript)|ensembl:ENST00000395587(transcript)|ensembl:ENST00000566501(transcript)|ensembl:ENST00000566866(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1902416"(positive regulation of mRNA binding)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR008905(Eukaryotic translation initiation factor 3 subunit 8, N-terminal)|interpro:IPR027516|interpro:IPR036388|interpro:IPR036390|mint:Q99613|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_001254503.1|dip:DIP-32865N - - comment:"author score: 40" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:9173bxjOdBfKj36pWVvzw7M6g1A9606 rogid:74XQwDW6yxVsob6wZNgfuBlB06M9606 rigid:K7Tc/kS/KJThP9549IijRxXlcys false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P06730 uniprotkb:Q13347 intact:EBI-73440|uniprotkb:Q96E95|ensembl:ENSP00000389624|uniprotkb:D6RCQ6|uniprotkb:B7Z6V1|intact:EBI-28969298 intact:EBI-354047|intact:EBI-11759480|ensembl:ENSP00000504034|ensembl:ENSP00000504061|ensembl:ENSP00000502867|ensembl:ENSP00000503348|ensembl:ENSP00000503539 psi-mi:if4e_human(display_long)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:EIF4E(gene name)|psi-mi:EIF4E(display_short)|uniprotkb:EIF4EL1(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:eif3i_human(display_long)|uniprotkb:EIF3I(gene name)|psi-mi:EIF3I(display_short)|uniprotkb:TRIP1(gene name synonym)|uniprotkb:EIF3S2(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 2(gene name synonym)|uniprotkb:eIF-3-beta(gene name synonym)|uniprotkb:eIF3 p36(gene name synonym)|uniprotkb:TGF-beta receptor-interacting protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478272|imex:IM-26985-321 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124151.1|refseq:NP_001959.1|ensembl:ENST00000280892|ensembl:ENSP00000280892|ensembl:ENSP00000389624|ensembl:ENST00000505992|ensembl:ENSP00000425561|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:2W97|rcsb pdb:3AM7|rcsb pdb:3TF2|rcsb pdb:3U7X|rcsb pdb:4AZA|rcsb pdb:4BEA|rcsb pdb:4DT6|rcsb pdb:4DUM|rcsb pdb:4TPW|rcsb pdb:4TQB|rcsb pdb:4TQC|rcsb pdb:4UED|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5EKV|rcsb pdb:5GW6|rcsb pdb:5T46|rcsb pdb:5ZJY|rcsb pdb:5ZJZ|rcsb pdb:5ZK5|rcsb pdb:5ZK7|rcsb pdb:5ZK9|ensembl:ENSG00000151247(gene)|rcsb pdb:5ZML|rcsb pdb:7MEU|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-159231|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-159230|reactome:R-HSA-159227|ensembl:ENST00000450253(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:P06730|rcsb pdb:1IPB|rcsb pdb:1IPC|rcsb pdb:1WKW|rcsb pdb:2GPQ|rcsb pdb:2V8W|refseq:NP_001124150.1|refseq:NP_001317946.1|dip:DIP-22N refseq:NP_003748.1|ensembl:ENST00000676801(transcript)|ensembl:ENST00000677202(transcript)|ensembl:ENST00000677701(transcript)|ensembl:ENST00000677711(transcript)|ensembl:ENST00000677760(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|ensembl:ENSG00000084623(gene)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR027525|interpro:IPR036322|mint:Q13347|rcsb pdb:6YBT|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-31116N - - comment:"author score: 40" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:9173bxjOdBfKj36pWVvzw7M6g1A9606 rogid:fogC6nSNmIynV2ziHZboT9laA3M9606 rigid:K7Tc/kS/KJThP9549IijRxXlcys false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P06730 uniprotkb:Q9Y262 intact:EBI-73440|uniprotkb:Q96E95|ensembl:ENSP00000389624|uniprotkb:D6RCQ6|uniprotkb:B7Z6V1|intact:EBI-28969298 intact:EBI-373519|uniprotkb:Q53HQ1|uniprotkb:Q53HT4|uniprotkb:Q5QTR1|uniprotkb:Q5TI15|uniprotkb:Q6ICD2|uniprotkb:B2RDG6|uniprotkb:B4DYB2|uniprotkb:G8JLH4|intact:EBI-10970119|ensembl:ENSP00000485663|ensembl:ENSP00000499067 psi-mi:if4e_human(display_long)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:EIF4E(gene name)|psi-mi:EIF4E(display_short)|uniprotkb:EIF4EL1(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:eif3l_human(display_long)|uniprotkb:EIF3L(gene name)|psi-mi:EIF3L(display_short)|uniprotkb:HSPC021(orf name)|uniprotkb:HSPC025(orf name)|uniprotkb:EIF3S6IP(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 6-interacting protein(gene name synonym)|uniprotkb:MSTP005(orf name)|uniprotkb:EIF3EIP(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit E-interacting protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478272|imex:IM-26985-321 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124151.1|refseq:NP_001959.1|ensembl:ENST00000280892|ensembl:ENSP00000280892|ensembl:ENSP00000389624|ensembl:ENST00000505992|ensembl:ENSP00000425561|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:2W97|rcsb pdb:3AM7|rcsb pdb:3TF2|rcsb pdb:3U7X|rcsb pdb:4AZA|rcsb pdb:4BEA|rcsb pdb:4DT6|rcsb pdb:4DUM|rcsb pdb:4TPW|rcsb pdb:4TQB|rcsb pdb:4TQC|rcsb pdb:4UED|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5EKV|rcsb pdb:5GW6|rcsb pdb:5T46|rcsb pdb:5ZJY|rcsb pdb:5ZJZ|rcsb pdb:5ZK5|rcsb pdb:5ZK7|rcsb pdb:5ZK9|ensembl:ENSG00000151247(gene)|rcsb pdb:5ZML|rcsb pdb:7MEU|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-159231|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-159230|reactome:R-HSA-159227|ensembl:ENST00000450253(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:P06730|rcsb pdb:1IPB|rcsb pdb:1IPC|rcsb pdb:1WKW|rcsb pdb:2GPQ|rcsb pdb:2V8W|refseq:NP_001124150.1|refseq:NP_001317946.1|dip:DIP-22N refseq:NP_057175.1|refseq:NP_001229852.1|dip:DIP-31172N|ensembl:ENSG00000100129(gene)|ensembl:ENST00000624234(transcript)|ensembl:ENST00000652021(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019382|mint:Q9Y262|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6FEC|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706 - - comment:"author score: 41" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:9173bxjOdBfKj36pWVvzw7M6g1A9606 rogid:C9ES0WpTdEHUkjWeZK/SoDP/dAo9606 rigid:K7Tc/kS/KJThP9549IijRxXlcys false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P06730 uniprotkb:O75821 intact:EBI-73440|uniprotkb:Q96E95|ensembl:ENSP00000389624|uniprotkb:D6RCQ6|uniprotkb:B7Z6V1|intact:EBI-28969298 intact:EBI-366632|uniprotkb:O14801|uniprotkb:Q969U5|intact:EBI-28974438|ensembl:ENSP00000253108 psi-mi:if4e_human(display_long)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:EIF4E(gene name)|psi-mi:EIF4E(display_short)|uniprotkb:EIF4EL1(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:eif3g_human(display_long)|uniprotkb:EIF3G(gene name)|psi-mi:EIF3G(display_short)|uniprotkb:EIF3S4(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 4(gene name synonym)|uniprotkb:eIF-3-delta(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 RNA-binding subunit(gene name synonym)|uniprotkb:eIF3 p44(gene name synonym)|uniprotkb:eIF3 p42(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478272|imex:IM-26985-321 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124151.1|refseq:NP_001959.1|ensembl:ENST00000280892|ensembl:ENSP00000280892|ensembl:ENSP00000389624|ensembl:ENST00000505992|ensembl:ENSP00000425561|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:2W97|rcsb pdb:3AM7|rcsb pdb:3TF2|rcsb pdb:3U7X|rcsb pdb:4AZA|rcsb pdb:4BEA|rcsb pdb:4DT6|rcsb pdb:4DUM|rcsb pdb:4TPW|rcsb pdb:4TQB|rcsb pdb:4TQC|rcsb pdb:4UED|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5EKV|rcsb pdb:5GW6|rcsb pdb:5T46|rcsb pdb:5ZJY|rcsb pdb:5ZJZ|rcsb pdb:5ZK5|rcsb pdb:5ZK7|rcsb pdb:5ZK9|ensembl:ENSG00000151247(gene)|rcsb pdb:5ZML|rcsb pdb:7MEU|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-159231|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-159230|reactome:R-HSA-159227|ensembl:ENST00000450253(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:P06730|rcsb pdb:1IPB|rcsb pdb:1IPC|rcsb pdb:1WKW|rcsb pdb:2GPQ|rcsb pdb:2V8W|refseq:NP_001124150.1|refseq:NP_001317946.1|dip:DIP-22N ensembl:ENSP00000253108|refseq:NP_003746.2|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017334(Translation initiation factor 3, RNA-binding subunit)|interpro:IPR024675|interpro:IPR034240|interpro:IPR035979|mint:O75821|rcsb pdb:2CQ0|rcsb pdb:2MJC|rcsb pdb:5K0Y|rcsb pdb:6YBS|rcsb pdb:6ZMW|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|ensembl:ENSG00000130811(gene)|ensembl:ENST00000253108(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|dip:DIP-31115N - - comment:"author score: 44" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:9173bxjOdBfKj36pWVvzw7M6g1A9606 rogid:ZHm8Il08Zyb6kFAavZo4tnuUN4g9606 rigid:K7Tc/kS/KJThP9549IijRxXlcys false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P06730 uniprotkb:O15372 intact:EBI-73440|uniprotkb:Q96E95|ensembl:ENSP00000389624|uniprotkb:D6RCQ6|uniprotkb:B7Z6V1|intact:EBI-28969298 intact:EBI-709735|ensembl:ENSP00000429931 psi-mi:if4e_human(display_long)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:EIF4E(gene name)|psi-mi:EIF4E(display_short)|uniprotkb:EIF4EL1(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:eif3h_human(display_long)|uniprotkb:EIF3S3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 3(gene name synonym)|uniprotkb:eIF-3-gamma(gene name synonym)|uniprotkb:eIF3 p40 subunit(gene name synonym)|uniprotkb:EIF3H(gene name)|psi-mi:EIF3H(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478272|imex:IM-26985-321 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124151.1|refseq:NP_001959.1|ensembl:ENST00000280892|ensembl:ENSP00000280892|ensembl:ENSP00000389624|ensembl:ENST00000505992|ensembl:ENSP00000425561|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:2W97|rcsb pdb:3AM7|rcsb pdb:3TF2|rcsb pdb:3U7X|rcsb pdb:4AZA|rcsb pdb:4BEA|rcsb pdb:4DT6|rcsb pdb:4DUM|rcsb pdb:4TPW|rcsb pdb:4TQB|rcsb pdb:4TQC|rcsb pdb:4UED|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5EKV|rcsb pdb:5GW6|rcsb pdb:5T46|rcsb pdb:5ZJY|rcsb pdb:5ZJZ|rcsb pdb:5ZK5|rcsb pdb:5ZK7|rcsb pdb:5ZK9|ensembl:ENSG00000151247(gene)|rcsb pdb:5ZML|rcsb pdb:7MEU|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-159231|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-159230|reactome:R-HSA-159227|ensembl:ENST00000450253(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:P06730|rcsb pdb:1IPB|rcsb pdb:1IPC|rcsb pdb:1WKW|rcsb pdb:2GPQ|rcsb pdb:2V8W|refseq:NP_001124150.1|refseq:NP_001317946.1|dip:DIP-22N refseq:NP_003747.1|ensembl:ENSG00000147677(gene)|ensembl:ENST00000521861(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070122"(isopeptidase activity)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0101005"(deubiquitinase activity)|interpro:IPR000555(Mov34/MPN/PAD-1)|interpro:IPR027524|interpro:IPR037518|mint:O15372|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-33689N - - comment:"author score: 44" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:9173bxjOdBfKj36pWVvzw7M6g1A9606 rogid:p1S78JRQsXwUzzAJkG02ABVWTNs9606 rigid:K7Tc/kS/KJThP9549IijRxXlcys false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P06730 uniprotkb:O15371 intact:EBI-73440|uniprotkb:Q96E95|ensembl:ENSP00000389624|uniprotkb:D6RCQ6|uniprotkb:B7Z6V1|intact:EBI-28969298 intact:EBI-353818|uniprotkb:Q3MJD9|uniprotkb:Q5M9Q6|uniprotkb:B2R7D4|intact:EBI-10969985|ensembl:ENSP00000216190|ensembl:ENSP00000385812|uniprotkb:A8MWD3|uniprotkb:B4DTF8|uniprotkb:B4DVY1 psi-mi:if4e_human(display_long)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:EIF4E(gene name)|psi-mi:EIF4E(display_short)|uniprotkb:EIF4EL1(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:eif3d_human(display_long)|uniprotkb:EIF3D(gene name)|psi-mi:EIF3D(display_short)|uniprotkb:EIF3S7(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 7(gene name synonym)|uniprotkb:eIF-3-zeta(gene name synonym)|uniprotkb:eIF3 p66(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478272|imex:IM-26985-321 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124151.1|refseq:NP_001959.1|ensembl:ENST00000280892|ensembl:ENSP00000280892|ensembl:ENSP00000389624|ensembl:ENST00000505992|ensembl:ENSP00000425561|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:2W97|rcsb pdb:3AM7|rcsb pdb:3TF2|rcsb pdb:3U7X|rcsb pdb:4AZA|rcsb pdb:4BEA|rcsb pdb:4DT6|rcsb pdb:4DUM|rcsb pdb:4TPW|rcsb pdb:4TQB|rcsb pdb:4TQC|rcsb pdb:4UED|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5EKV|rcsb pdb:5GW6|rcsb pdb:5T46|rcsb pdb:5ZJY|rcsb pdb:5ZJZ|rcsb pdb:5ZK5|rcsb pdb:5ZK7|rcsb pdb:5ZK9|ensembl:ENSG00000151247(gene)|rcsb pdb:5ZML|rcsb pdb:7MEU|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-159231|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-159230|reactome:R-HSA-159227|ensembl:ENST00000450253(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:P06730|rcsb pdb:1IPB|rcsb pdb:1IPC|rcsb pdb:1WKW|rcsb pdb:2GPQ|rcsb pdb:2V8W|refseq:NP_001124150.1|refseq:NP_001317946.1|dip:DIP-22N refseq:NP_003744.1|ensembl:ENSG00000100353(gene)|ensembl:ENST00000216190(transcript)|ensembl:ENST00000405442(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0002191"(cap-dependent translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0075525"(viral translational termination-reinitiation)|go:"GO:0098808"(mRNA cap binding)|go:"GO:1902416"(positive regulation of mRNA binding)|interpro:IPR007783(Eukaryotic translation initiation factor 3, subunit 7)|mint:O15371|rcsb pdb:6YBD|rcsb pdb:6YBS|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|dip:DIP-32870N - - comment:"author score: 48" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:9173bxjOdBfKj36pWVvzw7M6g1A9606 rogid:hw2nyiDfdecEhLmKA5U9+46bBag9606 rigid:K7Tc/kS/KJThP9549IijRxXlcys false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P06730 uniprotkb:P55884 intact:EBI-73440|uniprotkb:Q96E95|ensembl:ENSP00000389624|uniprotkb:D6RCQ6|uniprotkb:B7Z6V1|intact:EBI-28969298 intact:EBI-366696|uniprotkb:Q2NL77|uniprotkb:Q9UMF9|uniprotkb:A4D208|ensembl:ENSP00000354125|ensembl:ENSP00000380206 psi-mi:if4e_human(display_long)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:EIF4E(gene name)|psi-mi:EIF4E(display_short)|uniprotkb:EIF4EL1(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:eif3b_human(display_long)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 9(gene name synonym)|uniprotkb:eIF-3-eta(gene name synonym)|uniprotkb:eIF3 p116(gene name synonym)|uniprotkb:eIF3 p110(gene name synonym)|uniprotkb:Prt1 homolog(gene name synonym)|uniprotkb:EIF3B(gene name)|psi-mi:EIF3B(display_short)|uniprotkb:EIF3S9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478272|imex:IM-26985-321 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124151.1|refseq:NP_001959.1|ensembl:ENST00000280892|ensembl:ENSP00000280892|ensembl:ENSP00000389624|ensembl:ENST00000505992|ensembl:ENSP00000425561|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:2W97|rcsb pdb:3AM7|rcsb pdb:3TF2|rcsb pdb:3U7X|rcsb pdb:4AZA|rcsb pdb:4BEA|rcsb pdb:4DT6|rcsb pdb:4DUM|rcsb pdb:4TPW|rcsb pdb:4TQB|rcsb pdb:4TQC|rcsb pdb:4UED|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5EKV|rcsb pdb:5GW6|rcsb pdb:5T46|rcsb pdb:5ZJY|rcsb pdb:5ZJZ|rcsb pdb:5ZK5|rcsb pdb:5ZK7|rcsb pdb:5ZK9|ensembl:ENSG00000151247(gene)|rcsb pdb:5ZML|rcsb pdb:7MEU|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-159231|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-159230|reactome:R-HSA-159227|ensembl:ENST00000450253(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:P06730|rcsb pdb:1IPB|rcsb pdb:1IPC|rcsb pdb:1WKW|rcsb pdb:2GPQ|rcsb pdb:2V8W|refseq:NP_001124150.1|refseq:NP_001317946.1|dip:DIP-22N refseq:NP_001032360.1|refseq:NP_003742.2|refseq:XP_011513901.1|refseq:XP_011513902.1|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0031369"(translation initiation factor binding)|ensembl:ENSG00000106263(gene)|ensembl:ENST00000360876(transcript)|ensembl:ENST00000397011(transcript)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0045202"(synapse)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071541"(eukaryotic translation initiation factor 3 complex, eIF3m)|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:0075525"(viral translational termination-reinitiation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR011400(Translation initiation factor eIF-3b)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR034363|interpro:IPR035979|mint:P55884|rcsb pdb:2KRB|rcsb pdb:2NLW|rcsb pdb:5K1H|rcsb pdb:6YBT|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:XP_016868241.1|dip:DIP-31113N - - comment:"author score: 57" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:9173bxjOdBfKj36pWVvzw7M6g1A9606 rogid:MxQFPvmuOcO/S+4NqzToozWr8K89606 rigid:K7Tc/kS/KJThP9549IijRxXlcys false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P06730 uniprotkb:Q14240 intact:EBI-73440|uniprotkb:Q96E95|ensembl:ENSP00000389624|uniprotkb:D6RCQ6|uniprotkb:B7Z6V1|intact:EBI-28969298 intact:EBI-73473|intact:EBI-1058347|uniprotkb:Q96B90|uniprotkb:Q96EA8|intact:EBI-2831835|uniprotkb:Q53XJ6|uniprotkb:D3DNU9|ensembl:ENSP00000326381 psi-mi:if4e_human(display_long)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:EIF4E(gene name)|psi-mi:EIF4E(display_short)|uniprotkb:EIF4EL1(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:if4a2_human(display_long)|uniprotkb:ATP-dependent RNA helicase eIF4A-2(gene name synonym)|uniprotkb:EIF4A2(gene name)|psi-mi:EIF4A2(display_short)|uniprotkb:DDX2B(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478272|imex:IM-26985-321 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124151.1|refseq:NP_001959.1|ensembl:ENST00000280892|ensembl:ENSP00000280892|ensembl:ENSP00000389624|ensembl:ENST00000505992|ensembl:ENSP00000425561|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:2W97|rcsb pdb:3AM7|rcsb pdb:3TF2|rcsb pdb:3U7X|rcsb pdb:4AZA|rcsb pdb:4BEA|rcsb pdb:4DT6|rcsb pdb:4DUM|rcsb pdb:4TPW|rcsb pdb:4TQB|rcsb pdb:4TQC|rcsb pdb:4UED|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5EKV|rcsb pdb:5GW6|rcsb pdb:5T46|rcsb pdb:5ZJY|rcsb pdb:5ZJZ|rcsb pdb:5ZK5|rcsb pdb:5ZK7|rcsb pdb:5ZK9|ensembl:ENSG00000151247(gene)|rcsb pdb:5ZML|rcsb pdb:7MEU|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-159231|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-159230|reactome:R-HSA-159227|ensembl:ENST00000450253(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:P06730|rcsb pdb:1IPB|rcsb pdb:1IPC|rcsb pdb:1WKW|rcsb pdb:2GPQ|rcsb pdb:2V8W|refseq:NP_001124150.1|refseq:NP_001317946.1|dip:DIP-22N refseq:NP_001958.2|ensembl:ENSG00000156976(gene)|ensembl:ENST00000323963(transcript)|go:"GO:0002183"(cytoplasmic translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1900260"(negative regulation of RNA-directed 5'-3' RNA polymerase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044728|mint:Q14240|rcsb pdb:3BOR|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706 - - comment:"author score: 61" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:9173bxjOdBfKj36pWVvzw7M6g1A9606 rogid:m9i/jWfsbU+6kQvj1h06x31+awg9606 rigid:K7Tc/kS/KJThP9549IijRxXlcys false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P06730 uniprotkb:O43432 intact:EBI-73440|uniprotkb:Q96E95|ensembl:ENSP00000389624|uniprotkb:D6RCQ6|uniprotkb:B7Z6V1|intact:EBI-28969298 intact:EBI-464766|uniprotkb:Q5SWC3|ensembl:ENSP00000264211|uniprotkb:Q15597|uniprotkb:Q8NEN1|uniprotkb:Q504Z1|uniprotkb:B9EGQ7 psi-mi:if4e_human(display_long)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:EIF4E(gene name)|psi-mi:EIF4E(display_short)|uniprotkb:EIF4EL1(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:if4g3_human(display_long)|uniprotkb:EIF4G3(gene name)|psi-mi:EIF4G3(display_short)|uniprotkb:eIF-4-gamma II(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478272|imex:IM-26985-321 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124151.1|refseq:NP_001959.1|ensembl:ENST00000280892|ensembl:ENSP00000280892|ensembl:ENSP00000389624|ensembl:ENST00000505992|ensembl:ENSP00000425561|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:2W97|rcsb pdb:3AM7|rcsb pdb:3TF2|rcsb pdb:3U7X|rcsb pdb:4AZA|rcsb pdb:4BEA|rcsb pdb:4DT6|rcsb pdb:4DUM|rcsb pdb:4TPW|rcsb pdb:4TQB|rcsb pdb:4TQC|rcsb pdb:4UED|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5EKV|rcsb pdb:5GW6|rcsb pdb:5T46|rcsb pdb:5ZJY|rcsb pdb:5ZJZ|rcsb pdb:5ZK5|rcsb pdb:5ZK7|rcsb pdb:5ZK9|ensembl:ENSG00000151247(gene)|rcsb pdb:5ZML|rcsb pdb:7MEU|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-159231|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-159230|reactome:R-HSA-159227|ensembl:ENST00000450253(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:P06730|rcsb pdb:1IPB|rcsb pdb:1IPC|rcsb pdb:1WKW|rcsb pdb:2GPQ|rcsb pdb:2V8W|refseq:NP_001124150.1|refseq:NP_001317946.1|dip:DIP-22N ensembl:ENST00000264211(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR037585|mint:O43432|rcsb pdb:1HU3|reactome:R-HSA-1169408|ensembl:ENSG00000075151(gene)|refseq:NP_001185732.1|refseq:NP_003751.2|ensembl:ENSP00000264211|ensembl:ENST00000356916|ensembl:ENSP00000349386|ensembl:ENST00000374935|ensembl:ENSP00000364071|ensembl:ENST00000602326|ensembl:ENSP00000473510|ensembl:ENST00000682284|ensembl:ENSP00000507819|refseq:NP_001185731.1|refseq:NP_001185730.1|refseq:XP_016858189.1|refseq:XP_016858197.1|refseq:XP_016858201.1|dip:DIP-33245N - - comment:"author score: 91" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:9173bxjOdBfKj36pWVvzw7M6g1A9606 rogid:dN5046U5kz1WfBJD0+NWYMMU6RY9606 rigid:K7Tc/kS/KJThP9549IijRxXlcys false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P06730 uniprotkb:Q9NRA8 intact:EBI-73440|uniprotkb:Q96E95|ensembl:ENSP00000389624|uniprotkb:D6RCQ6|uniprotkb:B7Z6V1|intact:EBI-28969298 intact:EBI-301024|uniprotkb:B1AKL2|uniprotkb:Q8NCF2|uniprotkb:Q9H708|uniprotkb:B2RBF1|ensembl:ENSP00000328103|ensembl:ENSP00000380659|intact:EBI-877635|uniprotkb:B1AKL3 psi-mi:if4e_human(display_long)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:EIF4E(gene name)|psi-mi:EIF4E(display_short)|uniprotkb:EIF4EL1(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:4et_human(display_long)|uniprotkb:EIF4ENIF1(gene name)|psi-mi:EIF4ENIF1(display_short)|uniprotkb:Eukaryotic translation initiation factor 4E nuclear import factor 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478272|imex:IM-26985-321 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124151.1|refseq:NP_001959.1|ensembl:ENST00000280892|ensembl:ENSP00000280892|ensembl:ENSP00000389624|ensembl:ENST00000505992|ensembl:ENSP00000425561|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:2W97|rcsb pdb:3AM7|rcsb pdb:3TF2|rcsb pdb:3U7X|rcsb pdb:4AZA|rcsb pdb:4BEA|rcsb pdb:4DT6|rcsb pdb:4DUM|rcsb pdb:4TPW|rcsb pdb:4TQB|rcsb pdb:4TQC|rcsb pdb:4UED|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5EKV|rcsb pdb:5GW6|rcsb pdb:5T46|rcsb pdb:5ZJY|rcsb pdb:5ZJZ|rcsb pdb:5ZK5|rcsb pdb:5ZK7|rcsb pdb:5ZK9|ensembl:ENSG00000151247(gene)|rcsb pdb:5ZML|rcsb pdb:7MEU|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-159231|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-159230|reactome:R-HSA-159227|ensembl:ENST00000450253(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:P06730|rcsb pdb:1IPB|rcsb pdb:1IPC|rcsb pdb:1WKW|rcsb pdb:2GPQ|rcsb pdb:2V8W|refseq:NP_001124150.1|refseq:NP_001317946.1|dip:DIP-22N ensembl:ENSP00000328103|ensembl:ENST00000344710|ensembl:ENSP00000342927|ensembl:ENSP00000380659|ensembl:ENSG00000184708(gene)|ensembl:ENST00000330125(transcript)|ensembl:ENST00000397525(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0016020"(membrane)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019900"(kinase binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033962"(P-body assembly)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0106289"(negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR018862|mint:Q9NRA8|rcsb pdb:5ANR|rcsb pdb:6F9W|rcsb pdb:6X2R|refseq:NP_001157973.1|refseq:NP_001157974.1|refseq:NP_062817.2|refseq:XP_011528582.1|refseq:XP_011528583.1|refseq:XP_005261743.1|refseq:XP_005261744.1|refseq:XP_005261745.1|refseq:XP_016884353.1 - - comment:"author score: 112" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:9173bxjOdBfKj36pWVvzw7M6g1A9606 rogid:4A9mF81S/ePAraruTNYgovUdkT49606 rigid:K7Tc/kS/KJThP9549IijRxXlcys false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P06730 uniprotkb:Q13542 intact:EBI-73440|uniprotkb:Q96E95|ensembl:ENSP00000389624|uniprotkb:D6RCQ6|uniprotkb:B7Z6V1|intact:EBI-28969298 intact:EBI-935137|ensembl:ENSP00000362314 psi-mi:if4e_human(display_long)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:EIF4E(gene name)|psi-mi:EIF4E(display_short)|uniprotkb:EIF4EL1(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:4ebp2_human(display_long)|uniprotkb:EIF4EBP2(gene name)|psi-mi:EIF4EBP2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478272|imex:IM-26985-321 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124151.1|refseq:NP_001959.1|ensembl:ENST00000280892|ensembl:ENSP00000280892|ensembl:ENSP00000389624|ensembl:ENST00000505992|ensembl:ENSP00000425561|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:2W97|rcsb pdb:3AM7|rcsb pdb:3TF2|rcsb pdb:3U7X|rcsb pdb:4AZA|rcsb pdb:4BEA|rcsb pdb:4DT6|rcsb pdb:4DUM|rcsb pdb:4TPW|rcsb pdb:4TQB|rcsb pdb:4TQC|rcsb pdb:4UED|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5EKV|rcsb pdb:5GW6|rcsb pdb:5T46|rcsb pdb:5ZJY|rcsb pdb:5ZJZ|rcsb pdb:5ZK5|rcsb pdb:5ZK7|rcsb pdb:5ZK9|ensembl:ENSG00000151247(gene)|rcsb pdb:5ZML|rcsb pdb:7MEU|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-159231|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-159230|reactome:R-HSA-159227|ensembl:ENST00000450253(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:P06730|rcsb pdb:1IPB|rcsb pdb:1IPC|rcsb pdb:1WKW|rcsb pdb:2GPQ|rcsb pdb:2V8W|refseq:NP_001124150.1|refseq:NP_001317946.1|dip:DIP-22N refseq:NP_004087.1|dip:DIP-36572N|ensembl:ENSG00000148730(gene)|ensembl:ENST00000373218(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006412"(translation)|go:"GO:0007613"(memory)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0030371"(translation repressor activity)|go:"GO:0031929"(TOR signaling)|go:"GO:0035176"(social behavior)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0098794"(postsynapse)|interpro:IPR008606(Eukaryotic translation initiation factor 4E binding)|mint:Q13542|rcsb pdb:2MX4|rcsb pdb:3AM7 - - comment:"author score: 112" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:9173bxjOdBfKj36pWVvzw7M6g1A9606 rogid:EDzLBqy7pJvo45a3b6pHWOlRRQY9606 rigid:K7Tc/kS/KJThP9549IijRxXlcys false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P06730 uniprotkb:Q04637 intact:EBI-73440|uniprotkb:Q96E95|ensembl:ENSP00000389624|uniprotkb:D6RCQ6|uniprotkb:B7Z6V1|intact:EBI-28969298 intact:EBI-73711|uniprotkb:O43177|uniprotkb:O95066|uniprotkb:Q5HYG0|uniprotkb:Q6ZN21|uniprotkb:Q8N102|intact:EBI-11020102|uniprotkb:D3DNT4|uniprotkb:D3DNT5|uniprotkb:D3DNT2|uniprotkb:E9PFM1|uniprotkb:G5E9S1|intact:EBI-28974642|ensembl:ENSP00000316879 psi-mi:if4e_human(display_long)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:EIF4E(gene name)|psi-mi:EIF4E(display_short)|uniprotkb:EIF4EL1(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:if4g1_human(display_long)|uniprotkb:p220(gene name synonym)|uniprotkb:EIF4G1(gene name)|psi-mi:EIF4G1(display_short)|uniprotkb:EIF4G(gene name synonym)|uniprotkb:EIF4GI(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478272|imex:IM-26985-321 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124151.1|refseq:NP_001959.1|ensembl:ENST00000280892|ensembl:ENSP00000280892|ensembl:ENSP00000389624|ensembl:ENST00000505992|ensembl:ENSP00000425561|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:2W97|rcsb pdb:3AM7|rcsb pdb:3TF2|rcsb pdb:3U7X|rcsb pdb:4AZA|rcsb pdb:4BEA|rcsb pdb:4DT6|rcsb pdb:4DUM|rcsb pdb:4TPW|rcsb pdb:4TQB|rcsb pdb:4TQC|rcsb pdb:4UED|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5EKV|rcsb pdb:5GW6|rcsb pdb:5T46|rcsb pdb:5ZJY|rcsb pdb:5ZJZ|rcsb pdb:5ZK5|rcsb pdb:5ZK7|rcsb pdb:5ZK9|ensembl:ENSG00000151247(gene)|rcsb pdb:5ZML|rcsb pdb:7MEU|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-159231|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-159230|reactome:R-HSA-159227|ensembl:ENST00000450253(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:P06730|rcsb pdb:1IPB|rcsb pdb:1IPC|rcsb pdb:1WKW|rcsb pdb:2GPQ|rcsb pdb:2V8W|refseq:NP_001124150.1|refseq:NP_001317946.1|dip:DIP-22N ensembl:ENST00000342981|ensembl:ENSP00000343450|ensembl:ENSP00000316879|ensembl:ENST00000350481|ensembl:ENSP00000317600|ensembl:ENST00000352767|ensembl:ENSP00000338020|ensembl:ENST00000382330|ensembl:ENSP00000371767|ensembl:ENST00000392537|ensembl:ENSP00000376320|ensembl:ENST00000414031|ensembl:ENSP00000391935|ensembl:ENST00000424196|ensembl:ENSP00000416255|ensembl:ENST00000434061|ensembl:ENSP00000411826|refseq:NP_886553.3|refseq:NP_937884.1|refseq:NP_937885.1|refseq:NP_004944.3|dip:DIP-1161N|ensembl:ENSG00000114867(gene)|ensembl:ENST00000346169(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0002191"(cap-dependent translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016020"(membrane)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032502"(developmental process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034645"(cellular macromolecule biosynthetic process)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060964"(regulation of gene silencing by miRNA)|go:"GO:0080135"(regulation of cellular response to stress)|go:"GO:0097009"(energy homeostasis)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1905537"(positive regulation of eukaryotic translation initiation factor 4F complex assembly)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1905612"(positive regulation of mRNA cap binding)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1905696"(regulation of polysome binding)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR037584|mint:Q04637|rcsb pdb:1LJ2|rcsb pdb:1UG3|rcsb pdb:2W97|rcsb pdb:4AZA|rcsb pdb:4F02|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5T46|rcsb pdb:6ZMW|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957 - - comment:"author score: 128" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:9173bxjOdBfKj36pWVvzw7M6g1A9606 rogid:0UfVxxWOLUvrvFfcteeTc2RrbhA9606 rigid:K7Tc/kS/KJThP9549IijRxXlcys false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P06730 uniprotkb:Q13541 intact:EBI-73440|uniprotkb:Q96E95|ensembl:ENSP00000389624|uniprotkb:D6RCQ6|uniprotkb:B7Z6V1|intact:EBI-28969298 intact:EBI-74090|uniprotkb:B2R502|uniprotkb:Q6IBN3|uniprotkb:D3DSW8|ensembl:ENSP00000340691 psi-mi:if4e_human(display_long)|uniprotkb:mRNA cap-binding protein(gene name synonym)|uniprotkb:eIF-4F 25 kDa subunit(gene name synonym)|uniprotkb:EIF4E(gene name)|psi-mi:EIF4E(display_short)|uniprotkb:EIF4EL1(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:4ebp1_human(display_long)|uniprotkb:Phosphorylated heat- and acid-stable protein regulated by insulin 1(gene name synonym)|uniprotkb:EIF4EBP1(gene name)|psi-mi:EIF4EBP1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478272|imex:IM-26985-321 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124151.1|refseq:NP_001959.1|ensembl:ENST00000280892|ensembl:ENSP00000280892|ensembl:ENSP00000389624|ensembl:ENST00000505992|ensembl:ENSP00000425561|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:2W97|rcsb pdb:3AM7|rcsb pdb:3TF2|rcsb pdb:3U7X|rcsb pdb:4AZA|rcsb pdb:4BEA|rcsb pdb:4DT6|rcsb pdb:4DUM|rcsb pdb:4TPW|rcsb pdb:4TQB|rcsb pdb:4TQC|rcsb pdb:4UED|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5EKV|rcsb pdb:5GW6|rcsb pdb:5T46|rcsb pdb:5ZJY|rcsb pdb:5ZJZ|rcsb pdb:5ZK5|rcsb pdb:5ZK7|rcsb pdb:5ZK9|ensembl:ENSG00000151247(gene)|rcsb pdb:5ZML|rcsb pdb:7MEU|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-159231|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-159230|reactome:R-HSA-159227|ensembl:ENST00000450253(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0001662"(behavioral fear response)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030324"(lung development)|go:"GO:0031370"(eukaryotic initiation factor 4G binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099578"(regulation of translation at postsynapse, modulating synaptic transmission)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:P06730|rcsb pdb:1IPB|rcsb pdb:1IPC|rcsb pdb:1WKW|rcsb pdb:2GPQ|rcsb pdb:2V8W|refseq:NP_001124150.1|refseq:NP_001317946.1|dip:DIP-22N refseq:NP_004086.1|ensembl:ENSP00000340691|ensembl:ENSG00000187840(gene)|ensembl:ENST00000338825(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0002931"(response to ischemia)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|dip:DIP-30944N|go:"GO:0005829"(cytosol)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0030324"(lung development)|go:"GO:0030371"(translation repressor activity)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031929"(TOR signaling)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045471"(response to ethanol)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1990928"(response to amino acid starvation)|interpro:IPR008606(Eukaryotic translation initiation factor 4E binding)|interpro:IPR037582|mint:Q13541|rcsb pdb:1EJ4|rcsb pdb:1EJH|rcsb pdb:1WKW|rcsb pdb:2JGB|rcsb pdb:2JGC|rcsb pdb:2V8W|rcsb pdb:2V8X|rcsb pdb:2V8Y|rcsb pdb:3HXG|rcsb pdb:3HXI|rcsb pdb:3M93|rcsb pdb:3M94|rcsb pdb:3U7X|rcsb pdb:4UED|rcsb pdb:5BXV|rcsb pdb:5EKV|rcsb pdb:5NVN|rcsb pdb:5WBJ|rcsb pdb:6BCU|rcsb pdb:6BCX|reactome:R-HSA-166208|reactome:R-HSA-72662 - - comment:"author score: 286" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:9173bxjOdBfKj36pWVvzw7M6g1A9606 rogid:abkjWitYZ9erPSlC88IWI2FtKto9606 rigid:K7Tc/kS/KJThP9549IijRxXlcys false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P07305 uniprotkb:Q92522 intact:EBI-725224|uniprotkb:Q6FG88|uniprotkb:Q8N6R3|uniprotkb:B4DRD6|uniprotkb:B2R6I0|ensembl:ENSP00000344504 intact:EBI-876335|ensembl:ENSP00000329662 psi-mi:h10_human(display_long)|uniprotkb:H1-0(gene name)|psi-mi:H1-0(display_short)|uniprotkb:H1F0(gene name synonym)|uniprotkb:H1FV(gene name synonym)|uniprotkb:Histone H1'(gene name synonym)|uniprotkb:"Histone H1(0)"(gene name synonym) psi-mi:h1x_human(display_long)|uniprotkb:H1-10(gene name)|psi-mi:H1-10(display_short)|uniprotkb:H1FX(gene name synonym)|uniprotkb:Histone H1x(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478949|imex:IM-26985-399 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005309.1|ensembl:ENSG00000189060(gene)|ensembl:ENST00000340857(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016604"(nuclear body)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0005634"(nucleus)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P07305|rcsb pdb:6HQ1|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6N88|rcsb pdb:6N89|rcsb pdb:7DBP|rcsb pdb:7K5X|reactome:R-HSA-140342|reactome:R-HSA-2559584|dip:DIP-41775N ensembl:ENSG00000184897(gene)|ensembl:ENST00000333762(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045296"(cadherin binding)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:Q92522|refseq:NP_006017.1|dip:DIP-36358N|rcsb pdb:2LSO|rcsb pdb:6L9Z|rcsb pdb:7K60|rcsb pdb:7K63 - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:7ir9Jz/gNZypmWkTopCusDQFEhs9606 rogid:T+NweCoHXj0rYsS6gJ4V42R9MpA9606 rigid:OE4T07JD/Bleype566Owj8uiiXc false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P07305 uniprotkb:Q9UJ04 intact:EBI-725224|uniprotkb:Q6FG88|uniprotkb:Q8N6R3|uniprotkb:B4DRD6|uniprotkb:B2R6I0|ensembl:ENSP00000344504 intact:EBI-308511|ensembl:ENSP00000410943|uniprotkb:O94828|uniprotkb:Q96GW8|uniprotkb:B4DYQ2 psi-mi:h10_human(display_long)|uniprotkb:H1-0(gene name)|psi-mi:H1-0(display_short)|uniprotkb:H1F0(gene name synonym)|uniprotkb:H1FV(gene name synonym)|uniprotkb:Histone H1'(gene name synonym)|uniprotkb:"Histone H1(0)"(gene name synonym) psi-mi:tsyl4_human(display_long)|uniprotkb:TSPYL4(gene name)|psi-mi:TSPYL4(display_short)|uniprotkb:KIAA0721(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478949|imex:IM-26985-399 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005309.1|ensembl:ENSG00000189060(gene)|ensembl:ENST00000340857(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016604"(nuclear body)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0005634"(nucleus)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P07305|rcsb pdb:6HQ1|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6N88|rcsb pdb:6N89|rcsb pdb:7DBP|rcsb pdb:7K5X|reactome:R-HSA-140342|reactome:R-HSA-2559584|dip:DIP-41775N ensembl:ENSG00000187189(gene)|ensembl:ENST00000420283(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0042393"(histone binding)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q9UJ04|refseq:NP_067680.3 - - comment:"author score: 27" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:7ir9Jz/gNZypmWkTopCusDQFEhs9606 rogid:xcAq3OJVo+H+zV8Tq/wwdwthb3M9606 rigid:OE4T07JD/Bleype566Owj8uiiXc false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NPD3 uniprotkb:Q8TF46 intact:EBI-371823|ensembl:ENSP00000315476 intact:EBI-3672244|uniprotkb:Q8N1N8|uniprotkb:Q8WTU9|uniprotkb:Q96CM7|ensembl:ENSP00000321711 psi-mi:exos4_human(display_long)|uniprotkb:EXOSC4(gene name)|psi-mi:EXOSC4(display_short)|uniprotkb:RRP41(gene name synonym)|uniprotkb:SKI6(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Exosome component 4(gene name synonym)|uniprotkb:p12A(gene name synonym) psi-mi:di3l1_human(display_long)|uniprotkb:DIS3L1(gene name synonym)|uniprotkb:DIS3L(gene name)|psi-mi:DIS3L(display_short)|uniprotkb:KIAA1955(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478484|imex:IM-26985-325 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061910.1|ensembl:ENST00000316052(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000178896(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NPD3|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31165N refseq:NP_001137160.1|refseq:NP_588616.1|refseq:NP_001310865.1|refseq:NP_001310867.1|refseq:NP_001310868.1|refseq:NP_001310870.1|refseq:NP_001310874.1|refseq:NP_001310875.1|ensembl:ENSG00000166938(gene)|ensembl:ENST00000319212(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0019899"(enzyme binding)|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022966|interpro:IPR031192|interpro:IPR033770|interpro:IPR033771|interpro:IPR041505|mint:Q8TF46 - - comment:"author score: 69" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:74dinPWyzwhHXvgCm2h5gnCATQY9606 rogid:rxO2GoLqsuS4+/zLJsqCU8LFQyw9606 rigid:4qxTTC+cecndOOeNR+Ehcy778Og false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NPD3 uniprotkb:Q8WUB8 intact:EBI-371823|ensembl:ENSP00000315476 intact:EBI-716462|uniprotkb:Q2YDA3|uniprotkb:Q9BXD2|uniprotkb:Q53HG8|uniprotkb:Q9NV26|ensembl:ENSP00000341805 psi-mi:exos4_human(display_long)|uniprotkb:EXOSC4(gene name)|psi-mi:EXOSC4(display_short)|uniprotkb:RRP41(gene name synonym)|uniprotkb:SKI6(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Exosome component 4(gene name synonym)|uniprotkb:p12A(gene name synonym) psi-mi:phf10_human(display_long)|uniprotkb:XAP135(gene name synonym)|uniprotkb:PHF10(gene name)|psi-mi:PHF10(display_short)|uniprotkb:BAF45A(gene name synonym)|uniprotkb:BRG1-associated factor 45a(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478484|imex:IM-26985-325 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061910.1|ensembl:ENST00000316052(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000178896(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NPD3|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31165N refseq:NP_060758.2|refseq:NP_579866.2|ensembl:ENSG00000130024(gene)|ensembl:ENST00000339209(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071564"(npBAF complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR038045|mint:Q8WUB8 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:74dinPWyzwhHXvgCm2h5gnCATQY9606 rogid:QppOFkomM0Lm/7EjW4Fov8NhB049606 rigid:4qxTTC+cecndOOeNR+Ehcy778Og false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NPD3 uniprotkb:Q6Y7W6 intact:EBI-371823|ensembl:ENSP00000315476 intact:EBI-765394|uniprotkb:O75137|uniprotkb:Q7Z2Z8|uniprotkb:Q7Z3I2|uniprotkb:Q96HU4|uniprotkb:Q9NV82|uniprotkb:B9EG55|intact:EBI-10969943|uniprotkb:A6H8W4|uniprotkb:E9PBB0|ensembl:ENSP00000362664|ensembl:ENSP00000386537 psi-mi:exos4_human(display_long)|uniprotkb:EXOSC4(gene name)|psi-mi:EXOSC4(display_short)|uniprotkb:RRP41(gene name synonym)|uniprotkb:SKI6(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Exosome component 4(gene name synonym)|uniprotkb:p12A(gene name synonym) psi-mi:ggyf2_human(display_long)|uniprotkb:Trinucleotide repeat-containing gene 15 protein(gene name synonym)|uniprotkb:GIGYF2(gene name)|psi-mi:GIGYF2(display_short)|uniprotkb:KIAA0642(gene name synonym)|uniprotkb:TNRC15(gene name synonym)|uniprotkb:PERQ2(gene name synonym)|uniprotkb:PERQ amino acid-rich with GYF domain-containing protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478484|imex:IM-26985-325 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061910.1|ensembl:ENST00000316052(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000178896(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NPD3|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31165N refseq:NP_001096616.1|refseq:NP_056390.2|refseq:NP_001096617.1|refseq:NP_001096618.1|ensembl:ENSG00000204120(gene)|ensembl:ENST00000373563(transcript)|ensembl:ENST00000409547(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007631"(feeding behavior)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043204"(perikaryon)|go:"GO:0044267"(cellular protein metabolic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050881"(musculoskeletal movement)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0070064"(proline-rich region binding)|go:"GO:1990635"(proximal dendrite)|interpro:IPR003169(GYF)|interpro:IPR035445|rcsb pdb:5NVL|rcsb pdb:5NVM|mint:Q6Y7W6 - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:74dinPWyzwhHXvgCm2h5gnCATQY9606 rogid:LCnAT/BvynGfhb1p3KMftXk8S3Q9606 rigid:4qxTTC+cecndOOeNR+Ehcy778Og false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NPD3 uniprotkb:P42285 intact:EBI-371823|ensembl:ENSP00000315476 intact:EBI-347612|uniprotkb:Q2M386|uniprotkb:Q6MZZ8|uniprotkb:Q6P170|uniprotkb:Q8N5R0|uniprotkb:Q8TAG2|ensembl:ENSP00000230640 psi-mi:exos4_human(display_long)|uniprotkb:EXOSC4(gene name)|psi-mi:EXOSC4(display_short)|uniprotkb:RRP41(gene name synonym)|uniprotkb:SKI6(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Exosome component 4(gene name synonym)|uniprotkb:p12A(gene name synonym) psi-mi:mtrex_human(display_long)|uniprotkb:MTREX(gene name)|psi-mi:MTREX(display_short)|uniprotkb:DOB1(gene name synonym)|uniprotkb:KIAA0052(gene name synonym)|uniprotkb:MTR4(gene name synonym)|uniprotkb:SKIV2L2(gene name synonym)|uniprotkb:Superkiller viralicidic activity 2-like 2(gene name synonym)|uniprotkb:TRAMP-like complex helicase(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DOB1(gene name synonym)|uniprotkb:ATP-dependent RNA helicase SKIV2L2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478484|imex:IM-26985-325 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061910.1|ensembl:ENST00000316052(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000178896(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NPD3|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31165N refseq:NP_056175.3|ensembl:ENSG00000039123(gene)|ensembl:ENST00000230640(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016076"(snRNA catabolic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0031499"(TRAMP complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012961(DSH, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016438(RNA helicase, ATP-dependent, SK12/DOB1)|interpro:IPR025696|interpro:IPR027417|mint:P42285|rcsb pdb:6C90|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6IEG|rcsb pdb:6IEH|rcsb pdb:6RO1|reactome:R-HSA-6791226|reactome:R-HSA-72163 - - comment:"author score: 81" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:74dinPWyzwhHXvgCm2h5gnCATQY9606 rogid:bQdFDddFhetSp+CJ1S7Q5cm+g0k9606 rigid:4qxTTC+cecndOOeNR+Ehcy778Og false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NPD3 uniprotkb:Q99547 intact:EBI-371823|ensembl:ENSP00000315476 intact:EBI-373187|uniprotkb:B2RAF0|ensembl:ENSP00000258169 psi-mi:exos4_human(display_long)|uniprotkb:EXOSC4(gene name)|psi-mi:EXOSC4(display_short)|uniprotkb:RRP41(gene name synonym)|uniprotkb:SKI6(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Exosome component 4(gene name synonym)|uniprotkb:p12A(gene name synonym) psi-mi:mph6_human(display_long)|uniprotkb:MPHOSPH6(gene name)|psi-mi:MPHOSPH6(display_short)|uniprotkb:MPP6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478484|imex:IM-26985-325 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061910.1|ensembl:ENST00000316052(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000178896(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NPD3|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31165N refseq:NP_005783.2|ensembl:ENSG00000135698(gene)|ensembl:ENST00000258169(transcript)|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|interpro:IPR019324|mint:Q99547|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-6791226|dip:DIP-31131N - - comment:"author score: 110" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:74dinPWyzwhHXvgCm2h5gnCATQY9606 rogid:B53KiT1Bo6QC3Ckmf28PoKlRRms9606 rigid:4qxTTC+cecndOOeNR+Ehcy778Og false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NPD3 uniprotkb:Q9Y3B2 intact:EBI-371823|ensembl:ENSP00000315476 intact:EBI-371892|uniprotkb:Q5JTH3|uniprotkb:B2R9B3|ensembl:ENSP00000359939 psi-mi:exos4_human(display_long)|uniprotkb:EXOSC4(gene name)|psi-mi:EXOSC4(display_short)|uniprotkb:RRP41(gene name synonym)|uniprotkb:SKI6(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Exosome component 4(gene name synonym)|uniprotkb:p12A(gene name synonym) psi-mi:exos1_human(display_long)|uniprotkb:CSL4(gene name synonym)|uniprotkb:EXOSC1(gene name)|psi-mi:EXOSC1(display_short)|uniprotkb:CGI-108(orf name)|uniprotkb:Exosome component 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478484|imex:IM-26985-325 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061910.1|ensembl:ENST00000316052(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000178896(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NPD3|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31165N refseq:NP_057130.1|refseq:NP_001305291.1|refseq:NP_001305292.1|refseq:NP_001305293.1|refseq:NP_001305294.1|refseq:NP_001305295.1|ensembl:ENSG00000171311(gene)|ensembl:ENST00000370902(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR022967|interpro:IPR025721|interpro:IPR039771|mint:Q9Y3B2|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31261N - - comment:"author score: 143" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:74dinPWyzwhHXvgCm2h5gnCATQY9606 rogid:IBOBnAbHLduWe+40D2nLS1itYhY9606 rigid:4qxTTC+cecndOOeNR+Ehcy778Og false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NPD3 uniprotkb:Q06265 intact:EBI-371823|ensembl:ENSP00000315476 intact:EBI-347966|ensembl:ENSP00000243498|uniprotkb:Q12883|uniprotkb:Q86Y41|uniprotkb:Q86Y48|uniprotkb:Q4W5P5 psi-mi:exos4_human(display_long)|uniprotkb:EXOSC4(gene name)|psi-mi:EXOSC4(display_short)|uniprotkb:RRP41(gene name synonym)|uniprotkb:SKI6(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Exosome component 4(gene name synonym)|uniprotkb:p12A(gene name synonym) psi-mi:exos9_human(display_long)|uniprotkb:EXOSC9(gene name)|psi-mi:EXOSC9(display_short)|uniprotkb:PMSCL1(gene name synonym)|uniprotkb:Exosome component 9(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 1(gene name synonym)|uniprotkb:Autoantigen PM/Scl 1(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 75 kDa(gene name synonym)|uniprotkb:P75 polymyositis-scleroderma overlap syndrome-associated autoantigen(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478484|imex:IM-26985-325 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061910.1|ensembl:ENST00000316052(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000178896(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NPD3|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31165N go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006955"(immune response)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033100|interpro:IPR036345|mint:Q06265|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|ensembl:ENSG00000123737(gene)|ensembl:ENST00000243498(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|refseq:NP_001029366.1|refseq:NP_005024.2|dip:DIP-31286N - - comment:"author score: 165" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:74dinPWyzwhHXvgCm2h5gnCATQY9606 rogid:COzGZISdlfGlht1FhyxPhzbV9hY9606 rigid:4qxTTC+cecndOOeNR+Ehcy778Og false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NPD3 uniprotkb:Q5RKV6 intact:EBI-371823|ensembl:ENSP00000315476 intact:EBI-2841747|ensembl:ENSP00000398597 psi-mi:exos4_human(display_long)|uniprotkb:EXOSC4(gene name)|psi-mi:EXOSC4(display_short)|uniprotkb:RRP41(gene name synonym)|uniprotkb:SKI6(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Exosome component 4(gene name synonym)|uniprotkb:p12A(gene name synonym) psi-mi:exos6_human(display_long)|uniprotkb:EXOSC6(gene name)|psi-mi:EXOSC6(display_short)|uniprotkb:MTR3(gene name synonym)|uniprotkb:Exosome component 6(gene name synonym)|uniprotkb:mRNA transport regulator 3 homolog(gene name synonym)|uniprotkb:p11(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478484|imex:IM-26985-325 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061910.1|ensembl:ENST00000316052(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000178896(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NPD3|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31165N refseq:NP_478126.1|ensembl:ENSG00000223496(gene)|ensembl:ENST00000435634(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q5RKV6|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-61038N - - comment:"author score: 166" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:74dinPWyzwhHXvgCm2h5gnCATQY9606 rogid:tHH05GXmmH4GgRjtChjaGSLJ7Cc9606 rigid:4qxTTC+cecndOOeNR+Ehcy778Og false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NPD3 uniprotkb:Q01780 intact:EBI-371823|ensembl:ENSP00000315476 intact:EBI-358236|uniprotkb:B1AKQ1|uniprotkb:Q15158|uniprotkb:B1AKQ0|intact:EBI-28973393|ensembl:ENSP00000366135 psi-mi:exos4_human(display_long)|uniprotkb:EXOSC4(gene name)|psi-mi:EXOSC4(display_short)|uniprotkb:RRP41(gene name synonym)|uniprotkb:SKI6(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Exosome component 4(gene name synonym)|uniprotkb:p12A(gene name synonym) psi-mi:exosx_human(display_long)|uniprotkb:PMSCL2(gene name synonym)|uniprotkb:EXOSC10(gene name)|psi-mi:EXOSC10(display_short)|uniprotkb:PMSCL(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 2(gene name synonym)|uniprotkb:Autoantigen PM/Scl 2(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 100 kDa(gene name synonym)|uniprotkb:P100 polymyositis-scleroderma overlap syndrome-associated autoantigen(gene name synonym)|uniprotkb:RRP6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478484|imex:IM-26985-325 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061910.1|ensembl:ENST00000316052(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000178896(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NPD3|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31165N ensembl:ENST00000304457|ensembl:ENSP00000307307|ensembl:ENSP00000366135|refseq:NP_001001998.1|refseq:NP_002676.1|dip:DIP-31249N|ensembl:ENSG00000171824(gene)|ensembl:ENST00000376936(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071048"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|go:"GO:0016020"(membrane)|interpro:IPR010997(HRDC-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012588(Exosome-associated factor Rrp6, N-terminal)|interpro:IPR036397|mint:Q01780|rcsb pdb:2CPR|rcsb pdb:3SAF|rcsb pdb:3SAG|rcsb pdb:3SAH|rcsb pdb:6D6Q|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0035327"|rcsb pdb:6D6R|reactome:R-HSA-6791226|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process) - - comment:"author score: 170" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:74dinPWyzwhHXvgCm2h5gnCATQY9606 rogid:JeBuVE3nYxlFwYt/xUGlIC6ANJo9606 rigid:4qxTTC+cecndOOeNR+Ehcy778Og false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NPD3 uniprotkb:Q96B26 intact:EBI-371823|ensembl:ENSP00000315476 intact:EBI-371922|uniprotkb:O43480|uniprotkb:Q5TBA5|ensembl:ENSP00000374354 psi-mi:exos4_human(display_long)|uniprotkb:EXOSC4(gene name)|psi-mi:EXOSC4(display_short)|uniprotkb:RRP41(gene name synonym)|uniprotkb:SKI6(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Exosome component 4(gene name synonym)|uniprotkb:p12A(gene name synonym) psi-mi:exos8_human(display_long)|uniprotkb:OIP2(gene name synonym)|uniprotkb:RRP43(gene name synonym)|uniprotkb:EXOSC8(gene name)|psi-mi:EXOSC8(display_short)|uniprotkb:Ribosomal RNA-processing protein 43(gene name synonym)|uniprotkb:Exosome component 8(gene name synonym)|uniprotkb:p9(gene name synonym)|uniprotkb:Opa-interacting protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478484|imex:IM-26985-325 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061910.1|ensembl:ENST00000316052(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000178896(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NPD3|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31165N refseq:NP_852480.1|ensembl:ENSG00000120699(gene)|ensembl:ENST00000389704(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033196|go:"GO:0005829"(cytosol)|mint:Q96B26|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|interpro:IPR036345|dip:DIP-31133N - - comment:"author score: 180" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:74dinPWyzwhHXvgCm2h5gnCATQY9606 rogid:y/cReHiPMubzNruyETohBjbRick9606 rigid:4qxTTC+cecndOOeNR+Ehcy778Og false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NPD3 uniprotkb:Q15024 intact:EBI-371823|ensembl:ENSP00000315476 intact:EBI-371841|uniprotkb:Q96E72|ensembl:ENSP00000265564 psi-mi:exos4_human(display_long)|uniprotkb:EXOSC4(gene name)|psi-mi:EXOSC4(display_short)|uniprotkb:RRP41(gene name synonym)|uniprotkb:SKI6(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Exosome component 4(gene name synonym)|uniprotkb:p12A(gene name synonym) psi-mi:exos7_human(display_long)|uniprotkb:KIAA0116(gene name synonym)|uniprotkb:RRP42(gene name synonym)|uniprotkb:EXOSC7(gene name)|psi-mi:EXOSC7(display_short)|uniprotkb:Ribosomal RNA-processing protein 42(gene name synonym)|uniprotkb:Exosome component 7(gene name synonym)|uniprotkb:p8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478484|imex:IM-26985-325 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061910.1|ensembl:ENST00000316052(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000178896(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NPD3|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31165N refseq:NP_055819.2|ensembl:ENSG00000075914(gene)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|ensembl:ENST00000265564(transcript)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q15024|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|go:"GO:0034475"(U4 snRNA 3'-end processing)|dip:DIP-31266N - - comment:"author score: 195" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:74dinPWyzwhHXvgCm2h5gnCATQY9606 rogid:gFGj7nvYM3a56Pu7vryrP+XfUxE9606 rigid:4qxTTC+cecndOOeNR+Ehcy778Og false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NPD3 uniprotkb:Q13868 intact:EBI-371823|ensembl:ENSP00000315476 intact:EBI-301735|uniprotkb:Q9NUY4|uniprotkb:A3KFL3|ensembl:ENSP00000361433|uniprotkb:A3KFL4|uniprotkb:B4DKK6 psi-mi:exos4_human(display_long)|uniprotkb:EXOSC4(gene name)|psi-mi:EXOSC4(display_short)|uniprotkb:RRP41(gene name synonym)|uniprotkb:SKI6(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Exosome component 4(gene name synonym)|uniprotkb:p12A(gene name synonym) psi-mi:exos2_human(display_long)|uniprotkb:EXOSC2(gene name)|psi-mi:EXOSC2(display_short)|uniprotkb:RRP4(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 4(gene name synonym)|uniprotkb:Exosome component 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478484|imex:IM-26985-325 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061910.1|ensembl:ENST00000316052(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000178896(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NPD3|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31165N refseq:NP_055100.2|ensembl:ENSG00000130713(gene)|ensembl:ENST00000372358(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR025721|interpro:IPR026699|interpro:IPR036612|mint:Q13868|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|refseq:NP_001269638.1|dip:DIP-31264N|refseq:NP_001269637.1 - - comment:"author score: 225" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:74dinPWyzwhHXvgCm2h5gnCATQY9606 rogid:Lpl4OBbEYV2DRbYzLCPvbQdtaro9606 rigid:4qxTTC+cecndOOeNR+Ehcy778Og false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NPD3 uniprotkb:Q9NQT5 intact:EBI-371823|ensembl:ENSP00000315476 intact:EBI-371866|uniprotkb:Q5QP85|uniprotkb:Q9Y3A8|ensembl:ENSP00000323046|uniprotkb:A8K0K6 psi-mi:exos4_human(display_long)|uniprotkb:EXOSC4(gene name)|psi-mi:EXOSC4(display_short)|uniprotkb:RRP41(gene name synonym)|uniprotkb:SKI6(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Exosome component 4(gene name synonym)|uniprotkb:p12A(gene name synonym) psi-mi:exos3_human(display_long)|uniprotkb:EXOSC3(gene name)|psi-mi:EXOSC3(display_short)|uniprotkb:RRP40(gene name synonym)|uniprotkb:CGI-102(orf name)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:p10(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478484|imex:IM-26985-325 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061910.1|ensembl:ENST00000316052(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000178896(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NPD3|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31165N refseq:NP_001002269.1|refseq:NP_057126.2|ensembl:ENSG00000107371(gene)|ensembl:ENST00000327304(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q9NQT5|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29847N - - comment:"author score: 240" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:74dinPWyzwhHXvgCm2h5gnCATQY9606 rogid:ZyFFgoy7HM3oZ35I16XAH3jCook9606 rigid:4qxTTC+cecndOOeNR+Ehcy778Og false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NPD3 uniprotkb:Q9NQT4 intact:EBI-371823|ensembl:ENSP00000315476 intact:EBI-371876|uniprotkb:Q32Q81|uniprotkb:Q8NG16|uniprotkb:Q96I89|ensembl:ENSP00000221233 psi-mi:exos4_human(display_long)|uniprotkb:EXOSC4(gene name)|psi-mi:EXOSC4(display_short)|uniprotkb:RRP41(gene name synonym)|uniprotkb:SKI6(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 41(gene name synonym)|uniprotkb:Exosome component 4(gene name synonym)|uniprotkb:p12A(gene name synonym) psi-mi:exos5_human(display_long)|uniprotkb:EXOSC5(gene name)|psi-mi:EXOSC5(display_short)|uniprotkb:CML28(gene name synonym)|uniprotkb:RRP46(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:Exosome component 5(gene name synonym)|uniprotkb:p12B(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 28(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478484|imex:IM-26985-325 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061910.1|ensembl:ENST00000316052(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000178896(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NPD3|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31165N refseq:NP_064543.3|ensembl:ENSG00000077348(gene)|ensembl:ENST00000221233(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NQT4|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29846N - - comment:"author score: 283" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:74dinPWyzwhHXvgCm2h5gnCATQY9606 rogid:xrrhCz6a15mgW/t9HRyvTtrjKMQ9606 rigid:4qxTTC+cecndOOeNR+Ehcy778Og false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQT4 uniprotkb:Q13901 intact:EBI-371876|uniprotkb:Q32Q81|uniprotkb:Q8NG16|uniprotkb:Q96I89|ensembl:ENSP00000221233 intact:EBI-3844053|uniprotkb:A8K336|uniprotkb:D6W5F8|uniprotkb:Q05D64|ensembl:ENSP00000348107|ensembl:ENSP00000386468|ensembl:ENSP00000386779 psi-mi:exos5_human(display_long)|uniprotkb:EXOSC5(gene name)|psi-mi:EXOSC5(display_short)|uniprotkb:CML28(gene name synonym)|uniprotkb:RRP46(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:Exosome component 5(gene name synonym)|uniprotkb:p12B(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 28(gene name synonym) psi-mi:c1d_human(display_long)|uniprotkb:C1D(gene name)|psi-mi:C1D(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478532|imex:IM-26985-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064543.3|ensembl:ENSG00000077348(gene)|ensembl:ENST00000221233(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NQT4|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29846N refseq:NP_001177192.1|refseq:NP_001177194.1|refseq:NP_006324.1|refseq:NP_775269.1|ensembl:ENSG00000197223(gene)|ensembl:ENST00000355848(transcript)|ensembl:ENST00000409302(transcript)|ensembl:ENST00000410067(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017053"(transcription repressor complex)|interpro:IPR007146(Small-subunit processome, Utp3)|interpro:IPR011082(Exosome-associated factor Rrp47/DNA strand repair C1D)|mint:Q13901|reactome:R-HSA-6791226 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xrrhCz6a15mgW/t9HRyvTtrjKMQ9606 rogid:HewHUZfde5bSlgFrz+EdepfFCgk9606 rigid:b/9NJoMgyDpIGN/AmXkkRmq8ndM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQT4 uniprotkb:Q8TF46 intact:EBI-371876|uniprotkb:Q32Q81|uniprotkb:Q8NG16|uniprotkb:Q96I89|ensembl:ENSP00000221233 intact:EBI-3672244|uniprotkb:Q8N1N8|uniprotkb:Q8WTU9|uniprotkb:Q96CM7|ensembl:ENSP00000321711 psi-mi:exos5_human(display_long)|uniprotkb:EXOSC5(gene name)|psi-mi:EXOSC5(display_short)|uniprotkb:CML28(gene name synonym)|uniprotkb:RRP46(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:Exosome component 5(gene name synonym)|uniprotkb:p12B(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 28(gene name synonym) psi-mi:di3l1_human(display_long)|uniprotkb:DIS3L1(gene name synonym)|uniprotkb:DIS3L(gene name)|psi-mi:DIS3L(display_short)|uniprotkb:KIAA1955(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478532|imex:IM-26985-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064543.3|ensembl:ENSG00000077348(gene)|ensembl:ENST00000221233(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NQT4|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29846N refseq:NP_001137160.1|refseq:NP_588616.1|refseq:NP_001310865.1|refseq:NP_001310867.1|refseq:NP_001310868.1|refseq:NP_001310870.1|refseq:NP_001310874.1|refseq:NP_001310875.1|ensembl:ENSG00000166938(gene)|ensembl:ENST00000319212(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0019899"(enzyme binding)|interpro:IPR001900(Ribonuclease II and R)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022966|interpro:IPR031192|interpro:IPR033770|interpro:IPR033771|interpro:IPR041505|mint:Q8TF46 - - comment:"author score: 90" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xrrhCz6a15mgW/t9HRyvTtrjKMQ9606 rogid:rxO2GoLqsuS4+/zLJsqCU8LFQyw9606 rigid:b/9NJoMgyDpIGN/AmXkkRmq8ndM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQT4 uniprotkb:O60293 intact:EBI-371876|uniprotkb:Q32Q81|uniprotkb:Q8NG16|uniprotkb:Q96I89|ensembl:ENSP00000221233 intact:EBI-746701|intact:EBI-2874127|uniprotkb:Q6GMU1|uniprotkb:Q6P2S9|uniprotkb:Q6ZV36|uniprotkb:Q96BE7|ensembl:ENSP00000368017 psi-mi:exos5_human(display_long)|uniprotkb:EXOSC5(gene name)|psi-mi:EXOSC5(display_short)|uniprotkb:CML28(gene name synonym)|uniprotkb:RRP46(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:Exosome component 5(gene name synonym)|uniprotkb:p12B(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 28(gene name synonym) psi-mi:zc3h1_human(display_long)|uniprotkb:Proline/serine-rich coiled-coil protein 2(gene name synonym)|uniprotkb:ZFC3H1(gene name)|psi-mi:ZFC3H1(display_short)|uniprotkb:KIAA0546(gene name synonym)|uniprotkb:PSRC2(gene name synonym)|uniprotkb:CCDC131(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 131(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478532|imex:IM-26985-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064543.3|ensembl:ENSG00000077348(gene)|ensembl:ENST00000221233(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NQT4|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29846N refseq:NP_659419.3|ensembl:ENSG00000133858(gene)|ensembl:ENST00000378743(transcript)|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0006396"(RNA processing)|go:"GO:0046872"(metal ion binding)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019607|interpro:IPR039278|mint:O60293|ensembl:ENSP00000368017|ensembl:ENST00000548100|ensembl:ENSP00000450044|ensembl:ENST00000552994|ensembl:ENSP00000446995 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xrrhCz6a15mgW/t9HRyvTtrjKMQ9606 rogid:QJlOZNAOi6leWMDpXLZH6hYjMOk9606 rigid:b/9NJoMgyDpIGN/AmXkkRmq8ndM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQT4 uniprotkb:Q9NYB0 intact:EBI-371876|uniprotkb:Q32Q81|uniprotkb:Q8NG16|uniprotkb:Q96I89|ensembl:ENSP00000221233 intact:EBI-750109|uniprotkb:B4DQN4|uniprotkb:Q4W4Y2|uniprotkb:Q8WYZ3|uniprotkb:Q9NWR2|ensembl:ENSP00000300086 psi-mi:exos5_human(display_long)|uniprotkb:EXOSC5(gene name)|psi-mi:EXOSC5(display_short)|uniprotkb:CML28(gene name synonym)|uniprotkb:RRP46(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:Exosome component 5(gene name synonym)|uniprotkb:p12B(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 28(gene name synonym) psi-mi:te2ip_human(display_long)|uniprotkb:DRIP5(gene name synonym)|uniprotkb:TERF2IP(gene name)|psi-mi:TERF2IP(display_short)|uniprotkb:RAP1(gene name synonym)|uniprotkb:PP8000(orf name)|uniprotkb:Dopamine receptor-interacting protein 5(gene name synonym)|uniprotkb:Repressor/activator protein 1 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478532|imex:IM-26985-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064543.3|ensembl:ENSG00000077348(gene)|ensembl:ENST00000221233(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NQT4|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29846N ensembl:ENST00000300086(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|ensembl:ENSG00000166848(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016604"(nuclear body)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031848"(protection from non-homologous end joining at telomere)|refseq:NP_061848.2|dip:DIP-34868N|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032205"(negative regulation of telomere maintenance)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0048239"(negative regulation of DNA recombination at telomere)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0070187"(shelterin complex)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901985"(positive regulation of protein acetylation)|interpro:IPR001357(BRCT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015010(Rap1 Myb)|interpro:IPR021661|interpro:IPR036420|interpro:IPR038104|interpro:IPR039595|mint:Q9NYB0|rcsb pdb:1FEX|rcsb pdb:3K6G|rcsb pdb:4RQI|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-171319|reactome:R-HSA-174411|reactome:R-HSA-174414|reactome:R-HSA-174417|reactome:R-HSA-174430|reactome:R-HSA-174437|reactome:R-HSA-2559586|reactome:R-HSA-9670095 - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xrrhCz6a15mgW/t9HRyvTtrjKMQ9606 rogid:rH6GKcTfjxpXw0MAcOHQk29nz+09606 rigid:b/9NJoMgyDpIGN/AmXkkRmq8ndM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQT4 uniprotkb:Q9Y450 intact:EBI-371876|uniprotkb:Q32Q81|uniprotkb:Q8NG16|uniprotkb:Q96I89|ensembl:ENSP00000221233 intact:EBI-2868258|uniprotkb:Q5T7G3|uniprotkb:Q4VX90|uniprotkb:Q4VX89|uniprotkb:Q9UPW3|uniprotkb:Q8NDW9|uniprotkb:B7Z365|ensembl:ENSP00000356811 psi-mi:exos5_human(display_long)|uniprotkb:EXOSC5(gene name)|psi-mi:EXOSC5(display_short)|uniprotkb:CML28(gene name synonym)|uniprotkb:RRP46(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:Exosome component 5(gene name synonym)|uniprotkb:p12B(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 28(gene name synonym) psi-mi:hbs1l_human(display_long)|uniprotkb:HBS1L(gene name)|psi-mi:HBS1L(display_short)|uniprotkb:HBS1(gene name synonym)|uniprotkb:KIAA1038(gene name synonym)|uniprotkb:ERFS(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478532|imex:IM-26985-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064543.3|ensembl:ENSG00000077348(gene)|ensembl:ENST00000221233(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NQT4|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29846N refseq:NP_001138630.1|refseq:NP_001138679.1|refseq:NP_006611.1|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR015033(Region of unknown function DUF1916)|interpro:IPR027417|interpro:IPR037189|mint:Q9Y450|rcsb pdb:5LZW|rcsb pdb:5LZX|rcsb pdb:5LZY|rcsb pdb:5LZZ|reactome:R-HSA-429958|ensembl:ENSG00000112339(gene)|ensembl:ENST00000367837(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel) - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xrrhCz6a15mgW/t9HRyvTtrjKMQ9606 rogid:j93qk+f9rW1/Sem+tUzRay6UcKw9606 rigid:b/9NJoMgyDpIGN/AmXkkRmq8ndM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQT4 uniprotkb:Q6Y7W6 intact:EBI-371876|uniprotkb:Q32Q81|uniprotkb:Q8NG16|uniprotkb:Q96I89|ensembl:ENSP00000221233 intact:EBI-765394|uniprotkb:O75137|uniprotkb:Q7Z2Z8|uniprotkb:Q7Z3I2|uniprotkb:Q96HU4|uniprotkb:Q9NV82|uniprotkb:B9EG55|intact:EBI-10969943|uniprotkb:A6H8W4|uniprotkb:E9PBB0|ensembl:ENSP00000362664|ensembl:ENSP00000386537 psi-mi:exos5_human(display_long)|uniprotkb:EXOSC5(gene name)|psi-mi:EXOSC5(display_short)|uniprotkb:CML28(gene name synonym)|uniprotkb:RRP46(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:Exosome component 5(gene name synonym)|uniprotkb:p12B(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 28(gene name synonym) psi-mi:ggyf2_human(display_long)|uniprotkb:Trinucleotide repeat-containing gene 15 protein(gene name synonym)|uniprotkb:GIGYF2(gene name)|psi-mi:GIGYF2(display_short)|uniprotkb:KIAA0642(gene name synonym)|uniprotkb:TNRC15(gene name synonym)|uniprotkb:PERQ2(gene name synonym)|uniprotkb:PERQ amino acid-rich with GYF domain-containing protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478532|imex:IM-26985-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064543.3|ensembl:ENSG00000077348(gene)|ensembl:ENST00000221233(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NQT4|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29846N refseq:NP_001096616.1|refseq:NP_056390.2|refseq:NP_001096617.1|refseq:NP_001096618.1|ensembl:ENSG00000204120(gene)|ensembl:ENST00000373563(transcript)|ensembl:ENST00000409547(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007631"(feeding behavior)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043204"(perikaryon)|go:"GO:0044267"(cellular protein metabolic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050881"(musculoskeletal movement)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0070064"(proline-rich region binding)|go:"GO:1990635"(proximal dendrite)|interpro:IPR003169(GYF)|interpro:IPR035445|rcsb pdb:5NVL|rcsb pdb:5NVM|mint:Q6Y7W6 - - comment:"author score: 34" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xrrhCz6a15mgW/t9HRyvTtrjKMQ9606 rogid:LCnAT/BvynGfhb1p3KMftXk8S3Q9606 rigid:b/9NJoMgyDpIGN/AmXkkRmq8ndM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQT4 uniprotkb:O60573 intact:EBI-371876|uniprotkb:Q32Q81|uniprotkb:Q8NG16|uniprotkb:Q96I89|ensembl:ENSP00000221233 intact:EBI-398610|uniprotkb:O75349|uniprotkb:B8ZZJ9|ensembl:ENSP00000258416 psi-mi:exos5_human(display_long)|uniprotkb:EXOSC5(gene name)|psi-mi:EXOSC5(display_short)|uniprotkb:CML28(gene name synonym)|uniprotkb:RRP46(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:Exosome component 5(gene name synonym)|uniprotkb:p12B(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 28(gene name synonym) psi-mi:if4e2_human(display_long)|uniprotkb:EIF4E2(gene name)|psi-mi:EIF4E2(display_short)|uniprotkb:mRNA cap-binding protein type 3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4E-like 3(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 4E homologous protein(gene name synonym)|uniprotkb:mRNA cap-binding protein 4EHP(gene name synonym)|uniprotkb:eIF4E-like protein 4E-LP(gene name synonym)|uniprotkb:EIF4EL3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478532|imex:IM-26985-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064543.3|ensembl:ENSG00000077348(gene)|ensembl:ENST00000221233(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NQT4|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29846N refseq:NP_004837.1|dip:DIP-32578N|ensembl:ENSG00000135930(gene)|ensembl:ENST00000258416(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR001040("Eukaryotic translation initiation factor 4E (eIF-4E)")|interpro:IPR019770|interpro:IPR023398|mint:O60573|rcsb pdb:2JGB|rcsb pdb:2JGC|rcsb pdb:5NVK|rcsb pdb:5NVL|rcsb pdb:5NVM|rcsb pdb:5NVN|rcsb pdb:5XLN|reactome:R-HSA-1169408|refseq:NP_001263265.1 - - comment:"author score: 35" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xrrhCz6a15mgW/t9HRyvTtrjKMQ9606 rogid:fjre85PBJjEPNVrWjFUUX5NeuEE9606 rigid:b/9NJoMgyDpIGN/AmXkkRmq8ndM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQT4 uniprotkb:Q9Y580 intact:EBI-371876|uniprotkb:Q32Q81|uniprotkb:Q8NG16|uniprotkb:Q96I89|ensembl:ENSP00000221233 intact:EBI-746903|uniprotkb:Q9NUT4|uniprotkb:B2R6K8|ensembl:ENSP00000439918 psi-mi:exos5_human(display_long)|uniprotkb:EXOSC5(gene name)|psi-mi:EXOSC5(display_short)|uniprotkb:CML28(gene name synonym)|uniprotkb:RRP46(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:Exosome component 5(gene name synonym)|uniprotkb:p12B(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 28(gene name synonym) psi-mi:rbm7_human(display_long)|uniprotkb:RNA-binding motif protein 7(gene name synonym)|uniprotkb:RBM7(gene name)|psi-mi:RBM7(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478532|imex:IM-26985-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064543.3|ensembl:ENSG00000077348(gene)|ensembl:ENST00000221233(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NQT4|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29846N refseq:NP_001272974.1|refseq:NP_001272975.1|refseq:NP_001272976.1|refseq:NP_001272977.1|refseq:NP_057174.1|ensembl:ENSG00000076053(gene)|ensembl:ENST00000540163(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016076"(snRNA catabolic process)|go:"GO:0017069"(snRNA binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0097157"(pre-mRNA intronic binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034500|interpro:IPR035979|mint:Q9Y580|rcsb pdb:2M8H|rcsb pdb:5IQQ|rcsb pdb:5LXR|rcsb pdb:5LXY|dip:DIP-48833N - - comment:"author score: 47" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xrrhCz6a15mgW/t9HRyvTtrjKMQ9606 rogid:d39RjBQTHAVQlOsmrxMX0NCR8CU9606 rigid:b/9NJoMgyDpIGN/AmXkkRmq8ndM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQT4 uniprotkb:Q6NZY4 intact:EBI-371876|uniprotkb:Q32Q81|uniprotkb:Q8NG16|uniprotkb:Q96I89|ensembl:ENSP00000221233 intact:EBI-1263058|uniprotkb:Q7L2P6|uniprotkb:Q8N2K5|uniprotkb:Q96SK7|uniprotkb:Q9NSS2|uniprotkb:Q9NSS3|ensembl:ENSP00000488055|ensembl:ENSP00000500728 psi-mi:exos5_human(display_long)|uniprotkb:EXOSC5(gene name)|psi-mi:EXOSC5(display_short)|uniprotkb:CML28(gene name synonym)|uniprotkb:RRP46(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:Exosome component 5(gene name synonym)|uniprotkb:p12B(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 28(gene name synonym) psi-mi:zchc8_human(display_long)|uniprotkb:ZCCHC8(gene name)|psi-mi:ZCCHC8(display_short)|uniprotkb:TRAMP-like complex RNA-binding factor ZCCHC8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478532|imex:IM-26985-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064543.3|ensembl:ENSG00000077348(gene)|ensembl:ENST00000221233(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NQT4|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29846N refseq:NP_060082.2|ensembl:ENSG00000033030(gene)|ensembl:ENST00000633063(transcript)|ensembl:ENST00000672018(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016076"(snRNA catabolic process)|go:"GO:0016604"(nuclear body)|go:"GO:0031499"(TRAMP complex)|go:"GO:0034470"(ncRNA processing)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR006568(PSP, proline-rich)|mint:Q6NZY4|rcsb pdb:5LXR|rcsb pdb:5LXY|rcsb pdb:6C90 - - comment:"author score: 64" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xrrhCz6a15mgW/t9HRyvTtrjKMQ9606 rogid:dtjoaLAUgEGavPmqaJLPnLPHLP49606 rigid:b/9NJoMgyDpIGN/AmXkkRmq8ndM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQT4 uniprotkb:P42285 intact:EBI-371876|uniprotkb:Q32Q81|uniprotkb:Q8NG16|uniprotkb:Q96I89|ensembl:ENSP00000221233 intact:EBI-347612|uniprotkb:Q2M386|uniprotkb:Q6MZZ8|uniprotkb:Q6P170|uniprotkb:Q8N5R0|uniprotkb:Q8TAG2|ensembl:ENSP00000230640 psi-mi:exos5_human(display_long)|uniprotkb:EXOSC5(gene name)|psi-mi:EXOSC5(display_short)|uniprotkb:CML28(gene name synonym)|uniprotkb:RRP46(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:Exosome component 5(gene name synonym)|uniprotkb:p12B(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 28(gene name synonym) psi-mi:mtrex_human(display_long)|uniprotkb:MTREX(gene name)|psi-mi:MTREX(display_short)|uniprotkb:DOB1(gene name synonym)|uniprotkb:KIAA0052(gene name synonym)|uniprotkb:MTR4(gene name synonym)|uniprotkb:SKIV2L2(gene name synonym)|uniprotkb:Superkiller viralicidic activity 2-like 2(gene name synonym)|uniprotkb:TRAMP-like complex helicase(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DOB1(gene name synonym)|uniprotkb:ATP-dependent RNA helicase SKIV2L2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478532|imex:IM-26985-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064543.3|ensembl:ENSG00000077348(gene)|ensembl:ENST00000221233(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NQT4|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29846N refseq:NP_056175.3|ensembl:ENSG00000039123(gene)|ensembl:ENST00000230640(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016076"(snRNA catabolic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0031499"(TRAMP complex)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012961(DSH, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016438(RNA helicase, ATP-dependent, SK12/DOB1)|interpro:IPR025696|interpro:IPR027417|mint:P42285|rcsb pdb:6C90|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6IEG|rcsb pdb:6IEH|rcsb pdb:6RO1|reactome:R-HSA-6791226|reactome:R-HSA-72163 - - comment:"author score: 121" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xrrhCz6a15mgW/t9HRyvTtrjKMQ9606 rogid:bQdFDddFhetSp+CJ1S7Q5cm+g0k9606 rigid:b/9NJoMgyDpIGN/AmXkkRmq8ndM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQT4 uniprotkb:Q99547 intact:EBI-371876|uniprotkb:Q32Q81|uniprotkb:Q8NG16|uniprotkb:Q96I89|ensembl:ENSP00000221233 intact:EBI-373187|uniprotkb:B2RAF0|ensembl:ENSP00000258169 psi-mi:exos5_human(display_long)|uniprotkb:EXOSC5(gene name)|psi-mi:EXOSC5(display_short)|uniprotkb:CML28(gene name synonym)|uniprotkb:RRP46(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:Exosome component 5(gene name synonym)|uniprotkb:p12B(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 28(gene name synonym) psi-mi:mph6_human(display_long)|uniprotkb:MPHOSPH6(gene name)|psi-mi:MPHOSPH6(display_short)|uniprotkb:MPP6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478532|imex:IM-26985-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064543.3|ensembl:ENSG00000077348(gene)|ensembl:ENST00000221233(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NQT4|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29846N refseq:NP_005783.2|ensembl:ENSG00000135698(gene)|ensembl:ENST00000258169(transcript)|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|interpro:IPR019324|mint:Q99547|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-6791226|dip:DIP-31131N - - comment:"author score: 160" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xrrhCz6a15mgW/t9HRyvTtrjKMQ9606 rogid:B53KiT1Bo6QC3Ckmf28PoKlRRms9606 rigid:b/9NJoMgyDpIGN/AmXkkRmq8ndM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQT4 uniprotkb:Q5RKV6 intact:EBI-371876|uniprotkb:Q32Q81|uniprotkb:Q8NG16|uniprotkb:Q96I89|ensembl:ENSP00000221233 intact:EBI-2841747|ensembl:ENSP00000398597 psi-mi:exos5_human(display_long)|uniprotkb:EXOSC5(gene name)|psi-mi:EXOSC5(display_short)|uniprotkb:CML28(gene name synonym)|uniprotkb:RRP46(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:Exosome component 5(gene name synonym)|uniprotkb:p12B(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 28(gene name synonym) psi-mi:exos6_human(display_long)|uniprotkb:EXOSC6(gene name)|psi-mi:EXOSC6(display_short)|uniprotkb:MTR3(gene name synonym)|uniprotkb:Exosome component 6(gene name synonym)|uniprotkb:mRNA transport regulator 3 homolog(gene name synonym)|uniprotkb:p11(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478532|imex:IM-26985-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064543.3|ensembl:ENSG00000077348(gene)|ensembl:ENST00000221233(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NQT4|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29846N refseq:NP_478126.1|ensembl:ENSG00000223496(gene)|ensembl:ENST00000435634(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q5RKV6|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-61038N - - comment:"author score: 167" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xrrhCz6a15mgW/t9HRyvTtrjKMQ9606 rogid:tHH05GXmmH4GgRjtChjaGSLJ7Cc9606 rigid:b/9NJoMgyDpIGN/AmXkkRmq8ndM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQT4 uniprotkb:Q06265 intact:EBI-371876|uniprotkb:Q32Q81|uniprotkb:Q8NG16|uniprotkb:Q96I89|ensembl:ENSP00000221233 intact:EBI-347966|ensembl:ENSP00000243498|uniprotkb:Q12883|uniprotkb:Q86Y41|uniprotkb:Q86Y48|uniprotkb:Q4W5P5 psi-mi:exos5_human(display_long)|uniprotkb:EXOSC5(gene name)|psi-mi:EXOSC5(display_short)|uniprotkb:CML28(gene name synonym)|uniprotkb:RRP46(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:Exosome component 5(gene name synonym)|uniprotkb:p12B(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 28(gene name synonym) psi-mi:exos9_human(display_long)|uniprotkb:EXOSC9(gene name)|psi-mi:EXOSC9(display_short)|uniprotkb:PMSCL1(gene name synonym)|uniprotkb:Exosome component 9(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 1(gene name synonym)|uniprotkb:Autoantigen PM/Scl 1(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 75 kDa(gene name synonym)|uniprotkb:P75 polymyositis-scleroderma overlap syndrome-associated autoantigen(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478532|imex:IM-26985-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064543.3|ensembl:ENSG00000077348(gene)|ensembl:ENST00000221233(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NQT4|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29846N go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006955"(immune response)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033100|interpro:IPR036345|mint:Q06265|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|ensembl:ENSG00000123737(gene)|ensembl:ENST00000243498(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|refseq:NP_001029366.1|refseq:NP_005024.2|dip:DIP-31286N - - comment:"author score: 183" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xrrhCz6a15mgW/t9HRyvTtrjKMQ9606 rogid:COzGZISdlfGlht1FhyxPhzbV9hY9606 rigid:b/9NJoMgyDpIGN/AmXkkRmq8ndM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQT4 uniprotkb:Q9Y3B2 intact:EBI-371876|uniprotkb:Q32Q81|uniprotkb:Q8NG16|uniprotkb:Q96I89|ensembl:ENSP00000221233 intact:EBI-371892|uniprotkb:Q5JTH3|uniprotkb:B2R9B3|ensembl:ENSP00000359939 psi-mi:exos5_human(display_long)|uniprotkb:EXOSC5(gene name)|psi-mi:EXOSC5(display_short)|uniprotkb:CML28(gene name synonym)|uniprotkb:RRP46(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:Exosome component 5(gene name synonym)|uniprotkb:p12B(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 28(gene name synonym) psi-mi:exos1_human(display_long)|uniprotkb:CSL4(gene name synonym)|uniprotkb:EXOSC1(gene name)|psi-mi:EXOSC1(display_short)|uniprotkb:CGI-108(orf name)|uniprotkb:Exosome component 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478532|imex:IM-26985-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064543.3|ensembl:ENSG00000077348(gene)|ensembl:ENST00000221233(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NQT4|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29846N refseq:NP_057130.1|refseq:NP_001305291.1|refseq:NP_001305292.1|refseq:NP_001305293.1|refseq:NP_001305294.1|refseq:NP_001305295.1|ensembl:ENSG00000171311(gene)|ensembl:ENST00000370902(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019495|interpro:IPR022967|interpro:IPR025721|interpro:IPR039771|mint:Q9Y3B2|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-31261N - - comment:"author score: 194" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xrrhCz6a15mgW/t9HRyvTtrjKMQ9606 rogid:IBOBnAbHLduWe+40D2nLS1itYhY9606 rigid:b/9NJoMgyDpIGN/AmXkkRmq8ndM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQT4 uniprotkb:Q01780 intact:EBI-371876|uniprotkb:Q32Q81|uniprotkb:Q8NG16|uniprotkb:Q96I89|ensembl:ENSP00000221233 intact:EBI-358236|uniprotkb:B1AKQ1|uniprotkb:Q15158|uniprotkb:B1AKQ0|intact:EBI-28973393|ensembl:ENSP00000366135 psi-mi:exos5_human(display_long)|uniprotkb:EXOSC5(gene name)|psi-mi:EXOSC5(display_short)|uniprotkb:CML28(gene name synonym)|uniprotkb:RRP46(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:Exosome component 5(gene name synonym)|uniprotkb:p12B(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 28(gene name synonym) psi-mi:exosx_human(display_long)|uniprotkb:PMSCL2(gene name synonym)|uniprotkb:EXOSC10(gene name)|psi-mi:EXOSC10(display_short)|uniprotkb:PMSCL(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 2(gene name synonym)|uniprotkb:Autoantigen PM/Scl 2(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 100 kDa(gene name synonym)|uniprotkb:P100 polymyositis-scleroderma overlap syndrome-associated autoantigen(gene name synonym)|uniprotkb:RRP6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478532|imex:IM-26985-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064543.3|ensembl:ENSG00000077348(gene)|ensembl:ENST00000221233(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NQT4|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29846N ensembl:ENST00000304457|ensembl:ENSP00000307307|ensembl:ENSP00000366135|refseq:NP_001001998.1|refseq:NP_002676.1|dip:DIP-31249N|ensembl:ENSG00000171824(gene)|ensembl:ENST00000376936(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0004532"(exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071039"(nuclear polyadenylation-dependent CUT catabolic process)|go:"GO:0071040"(nuclear polyadenylation-dependent antisense transcript catabolic process)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071048"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:1904872"(regulation of telomerase RNA localization to Cajal body)|interpro:IPR002121(Helicase and RNase D C-terminal, HRDC)|interpro:IPR002562(3'-5' exonuclease)|go:"GO:0016020"(membrane)|interpro:IPR010997(HRDC-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012588(Exosome-associated factor Rrp6, N-terminal)|interpro:IPR036397|mint:Q01780|rcsb pdb:2CPR|rcsb pdb:3SAF|rcsb pdb:3SAG|rcsb pdb:3SAH|rcsb pdb:6D6Q|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0035327"|rcsb pdb:6D6R|reactome:R-HSA-6791226|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071036"(nuclear polyadenylation-dependent snoRNA catabolic process)|go:"GO:0071037"(nuclear polyadenylation-dependent snRNA catabolic process) - - comment:"author score: 255" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xrrhCz6a15mgW/t9HRyvTtrjKMQ9606 rogid:JeBuVE3nYxlFwYt/xUGlIC6ANJo9606 rigid:b/9NJoMgyDpIGN/AmXkkRmq8ndM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQT4 uniprotkb:Q96B26 intact:EBI-371876|uniprotkb:Q32Q81|uniprotkb:Q8NG16|uniprotkb:Q96I89|ensembl:ENSP00000221233 intact:EBI-371922|uniprotkb:O43480|uniprotkb:Q5TBA5|ensembl:ENSP00000374354 psi-mi:exos5_human(display_long)|uniprotkb:EXOSC5(gene name)|psi-mi:EXOSC5(display_short)|uniprotkb:CML28(gene name synonym)|uniprotkb:RRP46(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:Exosome component 5(gene name synonym)|uniprotkb:p12B(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 28(gene name synonym) psi-mi:exos8_human(display_long)|uniprotkb:OIP2(gene name synonym)|uniprotkb:RRP43(gene name synonym)|uniprotkb:EXOSC8(gene name)|psi-mi:EXOSC8(display_short)|uniprotkb:Ribosomal RNA-processing protein 43(gene name synonym)|uniprotkb:Exosome component 8(gene name synonym)|uniprotkb:p9(gene name synonym)|uniprotkb:Opa-interacting protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478532|imex:IM-26985-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064543.3|ensembl:ENSG00000077348(gene)|ensembl:ENST00000221233(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NQT4|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29846N refseq:NP_852480.1|ensembl:ENSG00000120699(gene)|ensembl:ENST00000389704(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033196|go:"GO:0005829"(cytosol)|mint:Q96B26|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|interpro:IPR036345|dip:DIP-31133N - - comment:"author score: 278" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xrrhCz6a15mgW/t9HRyvTtrjKMQ9606 rogid:y/cReHiPMubzNruyETohBjbRick9606 rigid:b/9NJoMgyDpIGN/AmXkkRmq8ndM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQT4 uniprotkb:Q15024 intact:EBI-371876|uniprotkb:Q32Q81|uniprotkb:Q8NG16|uniprotkb:Q96I89|ensembl:ENSP00000221233 intact:EBI-371841|uniprotkb:Q96E72|ensembl:ENSP00000265564 psi-mi:exos5_human(display_long)|uniprotkb:EXOSC5(gene name)|psi-mi:EXOSC5(display_short)|uniprotkb:CML28(gene name synonym)|uniprotkb:RRP46(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:Exosome component 5(gene name synonym)|uniprotkb:p12B(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 28(gene name synonym) psi-mi:exos7_human(display_long)|uniprotkb:KIAA0116(gene name synonym)|uniprotkb:RRP42(gene name synonym)|uniprotkb:EXOSC7(gene name)|psi-mi:EXOSC7(display_short)|uniprotkb:Ribosomal RNA-processing protein 42(gene name synonym)|uniprotkb:Exosome component 7(gene name synonym)|uniprotkb:p8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478532|imex:IM-26985-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064543.3|ensembl:ENSG00000077348(gene)|ensembl:ENST00000221233(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NQT4|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29846N refseq:NP_055819.2|ensembl:ENSG00000075914(gene)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|ensembl:ENST00000265564(transcript)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q15024|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|go:"GO:0034475"(U4 snRNA 3'-end processing)|dip:DIP-31266N - - comment:"author score: 278" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xrrhCz6a15mgW/t9HRyvTtrjKMQ9606 rogid:gFGj7nvYM3a56Pu7vryrP+XfUxE9606 rigid:b/9NJoMgyDpIGN/AmXkkRmq8ndM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQT4 uniprotkb:Q13868 intact:EBI-371876|uniprotkb:Q32Q81|uniprotkb:Q8NG16|uniprotkb:Q96I89|ensembl:ENSP00000221233 intact:EBI-301735|uniprotkb:Q9NUY4|uniprotkb:A3KFL3|ensembl:ENSP00000361433|uniprotkb:A3KFL4|uniprotkb:B4DKK6 psi-mi:exos5_human(display_long)|uniprotkb:EXOSC5(gene name)|psi-mi:EXOSC5(display_short)|uniprotkb:CML28(gene name synonym)|uniprotkb:RRP46(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:Exosome component 5(gene name synonym)|uniprotkb:p12B(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 28(gene name synonym) psi-mi:exos2_human(display_long)|uniprotkb:EXOSC2(gene name)|psi-mi:EXOSC2(display_short)|uniprotkb:RRP4(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 4(gene name synonym)|uniprotkb:Exosome component 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478532|imex:IM-26985-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064543.3|ensembl:ENSG00000077348(gene)|ensembl:ENST00000221233(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NQT4|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29846N refseq:NP_055100.2|ensembl:ENSG00000130713(gene)|ensembl:ENST00000372358(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR025721|interpro:IPR026699|interpro:IPR036612|mint:Q13868|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|refseq:NP_001269638.1|dip:DIP-31264N|refseq:NP_001269637.1 - - comment:"author score: 299" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xrrhCz6a15mgW/t9HRyvTtrjKMQ9606 rogid:Lpl4OBbEYV2DRbYzLCPvbQdtaro9606 rigid:b/9NJoMgyDpIGN/AmXkkRmq8ndM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQT4 uniprotkb:Q9NQT5 intact:EBI-371876|uniprotkb:Q32Q81|uniprotkb:Q8NG16|uniprotkb:Q96I89|ensembl:ENSP00000221233 intact:EBI-371866|uniprotkb:Q5QP85|uniprotkb:Q9Y3A8|ensembl:ENSP00000323046|uniprotkb:A8K0K6 psi-mi:exos5_human(display_long)|uniprotkb:EXOSC5(gene name)|psi-mi:EXOSC5(display_short)|uniprotkb:CML28(gene name synonym)|uniprotkb:RRP46(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 46(gene name synonym)|uniprotkb:Exosome component 5(gene name synonym)|uniprotkb:p12B(gene name synonym)|uniprotkb:Chronic myelogenous leukemia tumor antigen 28(gene name synonym) psi-mi:exos3_human(display_long)|uniprotkb:EXOSC3(gene name)|psi-mi:EXOSC3(display_short)|uniprotkb:RRP40(gene name synonym)|uniprotkb:CGI-102(orf name)|uniprotkb:Ribosomal RNA-processing protein 40(gene name synonym)|uniprotkb:Exosome component 3(gene name synonym)|uniprotkb:p10(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478532|imex:IM-26985-89 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064543.3|ensembl:ENSG00000077348(gene)|ensembl:ENST00000221233(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0051607"(defense response to virus)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q9NQT4|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29846N refseq:NP_001002269.1|refseq:NP_057126.2|ensembl:ENSG00000107371(gene)|ensembl:ENST00000327304(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0035327"|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR026699|interpro:IPR036612|interpro:IPR037319|mint:Q9NQT5|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-29847N - - comment:"author score: 341" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xrrhCz6a15mgW/t9HRyvTtrjKMQ9606 rogid:ZyFFgoy7HM3oZ35I16XAH3jCook9606 rigid:b/9NJoMgyDpIGN/AmXkkRmq8ndM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92800 uniprotkb:Q5T6S3 intact:EBI-8830732|uniprotkb:B4E3R7|uniprotkb:O43287|uniprotkb:A6NCH6|uniprotkb:Q14459|uniprotkb:Q53XP3|uniprotkb:B4DSS2|uniprotkb:B4DIJ1|uniprotkb:B4DIZ7|ensembl:ENSP00000404658|ensembl:ENSP00000466924 intact:EBI-2339674|uniprotkb:Q6N038|uniprotkb:Q32NF2|uniprotkb:Q8TBL6|uniprotkb:Q5T6S4|uniprotkb:Q9UFS9|ensembl:ENSP00000363003 psi-mi:ezh1_human(display_long)|uniprotkb:ENX-2(gene name synonym)|uniprotkb:Enhancer of zeste homolog 1(gene name synonym)|uniprotkb:KIAA0388(gene name synonym)|uniprotkb:EZH1(gene name)|psi-mi:EZH1(display_short) psi-mi:phf19_human(display_long)|uniprotkb:PHF19(gene name)|psi-mi:PHF19(display_short)|uniprotkb:PCL3(gene name synonym)|uniprotkb:Polycomb-like protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478595|imex:IM-26985-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308008.1|refseq:NP_001308010.1|refseq:NP_001308011.1|refseq:NP_001982.2|dip:DIP-58580N|ensembl:ENSG00000108799(gene)|ensembl:ENST00000428826(transcript)|ensembl:ENST00000592743(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0021766"(hippocampus development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0031507"(heterochromatin assembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR021654|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR032926|interpro:IPR041343|interpro:IPR041355|interpro:IPR044438|mint:Q92800|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP refseq:XP_011516811.1|refseq:NP_001009936.1|refseq:NP_056466.1|refseq:NP_001273769.1|refseq:NP_001273772.1|refseq:XP_005251963.1|refseq:XP_016870101.1|ensembl:ENSG00000119403(gene)|ensembl:ENST00000373896(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042017|mint:Q5T6S3|rcsb pdb:2E5Q|rcsb pdb:4BD3|rcsb pdb:6NQ3|rcsb pdb:6WAU|reactome:R-HSA-212300 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qp3eqBCgiaoA6VSSyqpW1d9YKN49606 rogid:K4sKpUT1htSiigJaEoGyDjvkWqc9606 rigid:pSjhGJCUDJh+rqyQlo0ADlUp5tA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92800 uniprotkb:Q92833 intact:EBI-8830732|uniprotkb:B4E3R7|uniprotkb:O43287|uniprotkb:A6NCH6|uniprotkb:Q14459|uniprotkb:Q53XP3|uniprotkb:B4DSS2|uniprotkb:B4DIJ1|uniprotkb:B4DIZ7|ensembl:ENSP00000404658|ensembl:ENSP00000466924 intact:EBI-1222720|uniprotkb:Q5U5L5|uniprotkb:A8K9Z6|uniprotkb:B7Z5S5|uniprotkb:Q86X63|uniprotkb:B7Z8L0|ensembl:ENSP00000341280 psi-mi:ezh1_human(display_long)|uniprotkb:ENX-2(gene name synonym)|uniprotkb:Enhancer of zeste homolog 1(gene name synonym)|uniprotkb:KIAA0388(gene name synonym)|uniprotkb:EZH1(gene name)|psi-mi:EZH1(display_short) psi-mi:jard2_human(display_long)|uniprotkb:JARID2(gene name)|psi-mi:JARID2(display_short)|uniprotkb:JMJ(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478595|imex:IM-26985-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308008.1|refseq:NP_001308010.1|refseq:NP_001308011.1|refseq:NP_001982.2|dip:DIP-58580N|ensembl:ENSG00000108799(gene)|ensembl:ENST00000428826(transcript)|ensembl:ENST00000592743(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0021766"(hippocampus development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0031507"(heterochromatin assembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR021654|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR032926|interpro:IPR041343|interpro:IPR041355|interpro:IPR044438|mint:Q92800|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP refseq:NP_004964.2|refseq:NP_001253969.1|refseq:XP_005249146.1|refseq:XP_016866323.1|refseq:XP_016866324.1|dip:DIP-45494N|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR036431|mint:Q92833|rcsb pdb:5HYN|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000008083(gene)|ensembl:ENST00000341776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007417"(central nervous system development)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0034721"(histone H3-K4 demethylation, trimethyl-H3-K4-specific)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex") - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qp3eqBCgiaoA6VSSyqpW1d9YKN49606 rogid:G/oMY7WdV7UyQwfT4MOZyET2fS89606 rigid:pSjhGJCUDJh+rqyQlo0ADlUp5tA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92800 uniprotkb:A6NED2 intact:EBI-8830732|uniprotkb:B4E3R7|uniprotkb:O43287|uniprotkb:A6NCH6|uniprotkb:Q14459|uniprotkb:Q53XP3|uniprotkb:B4DSS2|uniprotkb:B4DIJ1|uniprotkb:B4DIZ7|ensembl:ENSP00000404658|ensembl:ENSP00000466924 intact:EBI-21552314|ensembl:ENSP00000377801|ensembl:ENSP00000451963|uniprotkb:B2RTP9|uniprotkb:Q29RX6 psi-mi:ezh1_human(display_long)|uniprotkb:ENX-2(gene name synonym)|uniprotkb:Enhancer of zeste homolog 1(gene name synonym)|uniprotkb:KIAA0388(gene name synonym)|uniprotkb:EZH1(gene name)|psi-mi:EZH1(display_short) psi-mi:rccd1_human(display_long)|uniprotkb:RCCD1(gene name)|psi-mi:RCCD1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478595|imex:IM-26985-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308008.1|refseq:NP_001308010.1|refseq:NP_001308011.1|refseq:NP_001982.2|dip:DIP-58580N|ensembl:ENSG00000108799(gene)|ensembl:ENST00000428826(transcript)|ensembl:ENST00000592743(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0021766"(hippocampus development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0031507"(heterochromatin assembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR021654|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR032926|interpro:IPR041343|interpro:IPR041355|interpro:IPR044438|mint:Q92800|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP ensembl:ENSG00000166965(gene)|ensembl:ENST00000394258(transcript)|ensembl:ENST00000556618(transcript)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|mint:A6NED2|rcsb pdb:6F4R|rcsb pdb:6F4S|rcsb pdb:6F4T|refseq:NP_001017919.1|refseq:NP_291022.2 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qp3eqBCgiaoA6VSSyqpW1d9YKN49606 rogid:pJ4TNM7dmfISs5RIVzio/hBYHp09606 rigid:pSjhGJCUDJh+rqyQlo0ADlUp5tA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92800 uniprotkb:Q6ZN18 intact:EBI-8830732|uniprotkb:B4E3R7|uniprotkb:O43287|uniprotkb:A6NCH6|uniprotkb:Q14459|uniprotkb:Q53XP3|uniprotkb:B4DSS2|uniprotkb:B4DIJ1|uniprotkb:B4DIZ7|ensembl:ENSP00000404658|ensembl:ENSP00000466924 intact:EBI-743256|ensembl:ENSP00000381840|uniprotkb:Q59FS5|uniprotkb:Q6ZN62|uniprotkb:Q96BG3 psi-mi:ezh1_human(display_long)|uniprotkb:ENX-2(gene name synonym)|uniprotkb:Enhancer of zeste homolog 1(gene name synonym)|uniprotkb:KIAA0388(gene name synonym)|uniprotkb:EZH1(gene name)|psi-mi:EZH1(display_short) psi-mi:aebp2_human(display_long)|uniprotkb:Adipocyte enhancer-binding protein 2(gene name synonym)|uniprotkb:AEBP2(gene name)|psi-mi:AEBP2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478595|imex:IM-26985-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308008.1|refseq:NP_001308010.1|refseq:NP_001308011.1|refseq:NP_001982.2|dip:DIP-58580N|ensembl:ENSG00000108799(gene)|ensembl:ENST00000428826(transcript)|ensembl:ENST00000592743(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0021766"(hippocampus development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0031507"(heterochromatin assembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR021654|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR032926|interpro:IPR041343|interpro:IPR041355|interpro:IPR044438|mint:Q92800|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP ensembl:ENSG00000139154(gene)|interpro:IPR036236|ensembl:ENST00000398864(transcript)|go:"GO:0000785"(chromatin)|mint:Q6ZN18|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001107648.1|refseq:NP_694939.2|rcsb pdb:5WAI|rcsb pdb:5Y0U|rcsb pdb:5Y1U|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|reactome:R-HSA-3214841|refseq:NP_001253972.1|dip:DIP-58581N - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qp3eqBCgiaoA6VSSyqpW1d9YKN49606 rogid:mOY+NOTaqJlXjW8v6D3YPnfnfBU9606 rigid:pSjhGJCUDJh+rqyQlo0ADlUp5tA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92800 uniprotkb:Q16576 intact:EBI-8830732|uniprotkb:B4E3R7|uniprotkb:O43287|uniprotkb:A6NCH6|uniprotkb:Q14459|uniprotkb:Q53XP3|uniprotkb:B4DSS2|uniprotkb:B4DIJ1|uniprotkb:B4DIZ7|ensembl:ENSP00000404658|ensembl:ENSP00000466924 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 psi-mi:ezh1_human(display_long)|uniprotkb:ENX-2(gene name synonym)|uniprotkb:Enhancer of zeste homolog 1(gene name synonym)|uniprotkb:KIAA0388(gene name synonym)|uniprotkb:EZH1(gene name)|psi-mi:EZH1(display_short) psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478595|imex:IM-26985-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308008.1|refseq:NP_001308010.1|refseq:NP_001308011.1|refseq:NP_001982.2|dip:DIP-58580N|ensembl:ENSG00000108799(gene)|ensembl:ENST00000428826(transcript)|ensembl:ENST00000592743(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0021766"(hippocampus development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0031507"(heterochromatin assembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR021654|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR032926|interpro:IPR041343|interpro:IPR041355|interpro:IPR044438|mint:Q92800|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qp3eqBCgiaoA6VSSyqpW1d9YKN49606 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rigid:pSjhGJCUDJh+rqyQlo0ADlUp5tA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92800 uniprotkb:Q96JN0 intact:EBI-8830732|uniprotkb:B4E3R7|uniprotkb:O43287|uniprotkb:A6NCH6|uniprotkb:Q14459|uniprotkb:Q53XP3|uniprotkb:B4DSS2|uniprotkb:B4DIJ1|uniprotkb:B4DIZ7|ensembl:ENSP00000404658|ensembl:ENSP00000466924 intact:EBI-746045|uniprotkb:Q9H945|uniprotkb:Q9Y457|ensembl:ENSP00000348298|ensembl:ENSP00000360138|ensembl:ENSP00000360144|ensembl:ENSP00000501560|ensembl:ENSP00000501639|ensembl:ENSP00000502633|intact:EBI-8833163|uniprotkb:D3DR47|uniprotkb:Q5VW16|uniprotkb:Q7Z723|uniprotkb:Q86T32|uniprotkb:Q86T33|uniprotkb:Q8N3L6|uniprotkb:Q8N655 psi-mi:ezh1_human(display_long)|uniprotkb:ENX-2(gene name synonym)|uniprotkb:Enhancer of zeste homolog 1(gene name synonym)|uniprotkb:KIAA0388(gene name synonym)|uniprotkb:EZH1(gene name)|psi-mi:EZH1(display_short) psi-mi:lcor_human(display_long)|uniprotkb:LCOR(gene name)|psi-mi:LCOR(display_short)|uniprotkb:C10orf12(gene name synonym)|uniprotkb:KIAA1795(gene name synonym)|uniprotkb:MLR2(gene name synonym)|uniprotkb:Mblk1-related protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478595|imex:IM-26985-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308008.1|refseq:NP_001308010.1|refseq:NP_001308011.1|refseq:NP_001982.2|dip:DIP-58580N|ensembl:ENSG00000108799(gene)|ensembl:ENST00000428826(transcript)|ensembl:ENST00000592743(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0021766"(hippocampus development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0031507"(heterochromatin assembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR021654|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR032926|interpro:IPR041343|interpro:IPR041355|interpro:IPR044438|mint:Q92800|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP ensembl:ENSG00000196233(gene)|ensembl:ENST00000356016(transcript)|ensembl:ENST00000371097(transcript)|ensembl:ENST00000371103(transcript)|ensembl:ENST00000675471(transcript)|ensembl:ENST00000675537(transcript)|ensembl:ENST00000675971(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|mint:Q96JN0|rcsb pdb:2COB|refseq:NP_001164236.1|refseq:NP_001164237.1|refseq:NP_115816.2|refseq:XP_016872275.1|refseq:XP_016872276.1|refseq:XP_016872277.1|refseq:NP_001333445.1 - - comment:"author score: 36" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qp3eqBCgiaoA6VSSyqpW1d9YKN49606 rogid:cOnk6EDDff86yaG1uG+dxEQ1Z689606 rigid:pSjhGJCUDJh+rqyQlo0ADlUp5tA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92800 uniprotkb:O75530 intact:EBI-8830732|uniprotkb:B4E3R7|uniprotkb:O43287|uniprotkb:A6NCH6|uniprotkb:Q14459|uniprotkb:Q53XP3|uniprotkb:B4DSS2|uniprotkb:B4DIJ1|uniprotkb:B4DIZ7|ensembl:ENSP00000404658|ensembl:ENSP00000466924 intact:EBI-923794|intact:EBI-2839778|intact:EBI-1177693|uniprotkb:A8K7V5|uniprotkb:Q6NTH2|uniprotkb:Q7LDA5|uniprotkb:Q7LDG8|uniprotkb:Q86VV2|uniprotkb:Q9UNY7|uniprotkb:O00149|ensembl:ENSP00000263360|ensembl:ENSP00000500834 psi-mi:ezh1_human(display_long)|uniprotkb:ENX-2(gene name synonym)|uniprotkb:Enhancer of zeste homolog 1(gene name synonym)|uniprotkb:KIAA0388(gene name synonym)|uniprotkb:EZH1(gene name)|psi-mi:EZH1(display_short) psi-mi:eed_human(display_long)|uniprotkb:EED(gene name)|psi-mi:EED(display_short)|uniprotkb:WD protein associating with integrin cytoplasmic tails 1(gene name synonym)|uniprotkb:Embryonic ectoderm development protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478595|imex:IM-26985-15 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001308008.1|refseq:NP_001308010.1|refseq:NP_001308011.1|refseq:NP_001982.2|dip:DIP-58580N|ensembl:ENSG00000108799(gene)|ensembl:ENST00000428826(transcript)|ensembl:ENST00000592743(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0021766"(hippocampus development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0031507"(heterochromatin assembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR021654|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR032926|interpro:IPR041343|interpro:IPR041355|interpro:IPR044438|mint:Q92800|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP refseq:NP_003788.2|refseq:NP_001294936.1|dip:DIP-36673N|ensembl:ENSG00000074266(gene)|ensembl:ENST00000263360(transcript)|ensembl:ENST00000672825(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0021510"(spinal cord development)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:O75530|rcsb pdb:3IIW|rcsb pdb:3IIY|rcsb pdb:3IJ0|rcsb pdb:3IJ1|rcsb pdb:3IJC|rcsb pdb:3JPX|rcsb pdb:3JZG|rcsb pdb:3JZH|rcsb pdb:3JZN|rcsb pdb:3K26|rcsb pdb:3K27|rcsb pdb:4W2R|rcsb pdb:4X3E|rcsb pdb:5GSA|rcsb pdb:5H13|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5K0M|rcsb pdb:5LS6|rcsb pdb:5TTW|rcsb pdb:5U5H|rcsb pdb:5U5K|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5U69|rcsb pdb:5U6D|rcsb pdb:5U8A|rcsb pdb:5U8F|rcsb pdb:5WG6|rcsb pdb:5WP3|rcsb pdb:5WUK|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6SFB|rcsb pdb:6SFC|rcsb pdb:6U4Y|rcsb pdb:6V3X|rcsb pdb:6V3Y|rcsb pdb:6W7F|rcsb pdb:6W7G|rcsb pdb:6WKR|rcsb pdb:6YVI|rcsb pdb:6YVJ|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7KXT|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421 - - comment:"author score: 73" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qp3eqBCgiaoA6VSSyqpW1d9YKN49606 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA9606 rigid:pSjhGJCUDJh+rqyQlo0ADlUp5tA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15910 uniprotkb:Q15233 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 intact:EBI-350527|ensembl:ENSP00000503233|uniprotkb:O00201|uniprotkb:P30807|uniprotkb:Q12786|uniprotkb:Q9BQC5|ensembl:ENSP00000276079|ensembl:ENSP00000362947|ensembl:ENSP00000406673|ensembl:ENSP00000410299|ensembl:ENSP00000415777|ensembl:ENSP00000503031|ensembl:ENSP00000504314|ensembl:ENSP00000504351|uniprotkb:D3DVV4|uniprotkb:B7Z4C2|uniprotkb:F5GYZ3 psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:nono_human(display_long)|uniprotkb:NONO(gene name)|psi-mi:NONO(display_short)|uniprotkb:NRB54(gene name synonym)|uniprotkb:54 kDa nuclear RNA- and DNA-binding protein(gene name synonym)|uniprotkb:"p54(nrb)"(gene name synonym)|uniprotkb:55 kDa nuclear protein(gene name synonym)|uniprotkb:NMT55(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 52 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478622|imex:IM-26985-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N refseq:NP_001138880.1|refseq:NP_001138881.1|refseq:NP_001138882.1|refseq:NP_031389.3|ensembl:ENSG00000147140(gene)|ensembl:ENST00000276079(transcript)|ensembl:ENST00000373841(transcript)|ensembl:ENST00000420903(transcript)|ensembl:ENST00000450092(transcript)|ensembl:ENST00000454976(transcript)|ensembl:ENST00000677274(transcript)|ensembl:ENST00000677446(transcript)|ensembl:ENST00000677612(transcript)|ensembl:ENST00000678231(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0042382"(paraspeckles)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034552|interpro:IPR035979|mint:Q15233|rcsb pdb:3SDE|rcsb pdb:5IFM|rcsb pdb:6WMZ|rcsb pdb:7LRQ|dip:DIP-29951N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 rogid:5W3ooO4h0qh3GKO+WjDrLBhihHA9606 rigid:tOJ17NgPRC/uH7LvBNRk7Du4u10 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15910 uniprotkb:Q9BYD2 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 intact:EBI-726059|uniprotkb:Q9BSW8|uniprotkb:Q5SZR2|uniprotkb:B2RD99|ensembl:ENSP00000357823 psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:rm09_human(display_long)|uniprotkb:MRPL9(gene name)|psi-mi:MRPL9(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein bL9m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478622|imex:IM-26985-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N refseq:NP_113608.1|refseq:NP_001287662.1|ensembl:ENSG00000143436(gene)|ensembl:ENST00000368830(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|interpro:IPR000244(Ribosomal protein L9)|interpro:IPR009027(Ribosomal protein L9 N-terminal-like)|interpro:IPR020070|interpro:IPR036935|mint:Q9BYD2|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 rogid:JeHxoAdUc13d+0EnTCGBAa9rlVc9606 rigid:tOJ17NgPRC/uH7LvBNRk7Du4u10 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15910 uniprotkb:Q5T6S3 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 intact:EBI-2339674|uniprotkb:Q6N038|uniprotkb:Q32NF2|uniprotkb:Q8TBL6|uniprotkb:Q5T6S4|uniprotkb:Q9UFS9|ensembl:ENSP00000363003 psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:phf19_human(display_long)|uniprotkb:PHF19(gene name)|psi-mi:PHF19(display_short)|uniprotkb:PCL3(gene name synonym)|uniprotkb:Polycomb-like protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478622|imex:IM-26985-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N refseq:XP_011516811.1|refseq:NP_001009936.1|refseq:NP_056466.1|refseq:NP_001273769.1|refseq:NP_001273772.1|refseq:XP_005251963.1|refseq:XP_016870101.1|ensembl:ENSG00000119403(gene)|ensembl:ENST00000373896(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042017|mint:Q5T6S3|rcsb pdb:2E5Q|rcsb pdb:4BD3|rcsb pdb:6NQ3|rcsb pdb:6WAU|reactome:R-HSA-212300 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 rogid:K4sKpUT1htSiigJaEoGyDjvkWqc9606 rigid:tOJ17NgPRC/uH7LvBNRk7Du4u10 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15910 uniprotkb:A6NHQ4 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 intact:EBI-8831125|ensembl:ENSP00000483859|ensembl:ENSP00000484710 psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:epop_human(display_long)|uniprotkb:EPOP(gene name)|psi-mi:EPOP(display_short)|uniprotkb:C17orf96(gene name synonym)|uniprotkb:PRR28(gene name synonym)|uniprotkb:Proline-rich protein 28(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478622|imex:IM-26985-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N refseq:NP_001124149.1|ensembl:ENSG00000273604(gene)|ensembl:ENST00000613024(transcript)|ensembl:ENST00000621654(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005694"(chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0048663"(neuron fate commitment)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0070449"(elongin complex)|interpro:IPR027971|mint:A6NHQ4|ensembl:ENSG00000277303(gene) - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 rogid:xxrapCjRxgY22pLac2F4zSS2bvk9606 rigid:tOJ17NgPRC/uH7LvBNRk7Du4u10 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15910 uniprotkb:Q9H7H0 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 intact:EBI-749353|intact:EBI-948255|uniprotkb:Q9BSH1|uniprotkb:Q9BZH2|uniprotkb:Q9BZH3|ensembl:ENSP00000343041 psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:met17_human(display_long)|uniprotkb:METT11D1(gene name synonym)|uniprotkb:Protein RSM22 homolog, mitochondrial(gene name synonym)|uniprotkb:METTL17(gene name)|psi-mi:METTL17(display_short)|uniprotkb:Methyltransferase 11 domain-containing protein 1(gene name synonym)|uniprotkb:False p73 target gene protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478622|imex:IM-26985-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N refseq:NP_001025162.1|refseq:NP_073571.1|ensembl:ENSG00000165792(gene)|ensembl:ENST00000339374(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006412"(translation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0032259"(methylation)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR015324(Ribosomal protein Rsm22, bacterial-type)|interpro:IPR029063|mint:Q9H7H0 - - comment:"author score: 27" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 rogid:RAj8jOqwthd7a0Xzi5FWhVKc8OI9606 rigid:tOJ17NgPRC/uH7LvBNRk7Du4u10 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15910 uniprotkb:Q6ZN18 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 intact:EBI-743256|ensembl:ENSP00000381840|uniprotkb:Q59FS5|uniprotkb:Q6ZN62|uniprotkb:Q96BG3 psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:aebp2_human(display_long)|uniprotkb:Adipocyte enhancer-binding protein 2(gene name synonym)|uniprotkb:AEBP2(gene name)|psi-mi:AEBP2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478622|imex:IM-26985-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N ensembl:ENSG00000139154(gene)|interpro:IPR036236|ensembl:ENST00000398864(transcript)|go:"GO:0000785"(chromatin)|mint:Q6ZN18|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001107648.1|refseq:NP_694939.2|rcsb pdb:5WAI|rcsb pdb:5Y0U|rcsb pdb:5Y1U|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|reactome:R-HSA-3214841|refseq:NP_001253972.1|dip:DIP-58581N - - comment:"author score: 36" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 rogid:mOY+NOTaqJlXjW8v6D3YPnfnfBU9606 rigid:tOJ17NgPRC/uH7LvBNRk7Du4u10 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15910 uniprotkb:Q16576 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478622|imex:IM-26985-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N - - comment:"author score: 37" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rigid:tOJ17NgPRC/uH7LvBNRk7Du4u10 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15910 uniprotkb:Q96JN0 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 intact:EBI-746045|uniprotkb:Q9H945|uniprotkb:Q9Y457|ensembl:ENSP00000348298|ensembl:ENSP00000360138|ensembl:ENSP00000360144|ensembl:ENSP00000501560|ensembl:ENSP00000501639|ensembl:ENSP00000502633|intact:EBI-8833163|uniprotkb:D3DR47|uniprotkb:Q5VW16|uniprotkb:Q7Z723|uniprotkb:Q86T32|uniprotkb:Q86T33|uniprotkb:Q8N3L6|uniprotkb:Q8N655 psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:lcor_human(display_long)|uniprotkb:LCOR(gene name)|psi-mi:LCOR(display_short)|uniprotkb:C10orf12(gene name synonym)|uniprotkb:KIAA1795(gene name synonym)|uniprotkb:MLR2(gene name synonym)|uniprotkb:Mblk1-related protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478622|imex:IM-26985-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N ensembl:ENSG00000196233(gene)|ensembl:ENST00000356016(transcript)|ensembl:ENST00000371097(transcript)|ensembl:ENST00000371103(transcript)|ensembl:ENST00000675471(transcript)|ensembl:ENST00000675537(transcript)|ensembl:ENST00000675971(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|mint:Q96JN0|rcsb pdb:2COB|refseq:NP_001164236.1|refseq:NP_001164237.1|refseq:NP_115816.2|refseq:XP_016872275.1|refseq:XP_016872276.1|refseq:XP_016872277.1|refseq:NP_001333445.1 - - comment:"author score: 41" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 rogid:cOnk6EDDff86yaG1uG+dxEQ1Z689606 rigid:tOJ17NgPRC/uH7LvBNRk7Du4u10 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15910 uniprotkb:O75530 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 intact:EBI-923794|intact:EBI-2839778|intact:EBI-1177693|uniprotkb:A8K7V5|uniprotkb:Q6NTH2|uniprotkb:Q7LDA5|uniprotkb:Q7LDG8|uniprotkb:Q86VV2|uniprotkb:Q9UNY7|uniprotkb:O00149|ensembl:ENSP00000263360|ensembl:ENSP00000500834 psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:eed_human(display_long)|uniprotkb:EED(gene name)|psi-mi:EED(display_short)|uniprotkb:WD protein associating with integrin cytoplasmic tails 1(gene name synonym)|uniprotkb:Embryonic ectoderm development protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478622|imex:IM-26985-91 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N refseq:NP_003788.2|refseq:NP_001294936.1|dip:DIP-36673N|ensembl:ENSG00000074266(gene)|ensembl:ENST00000263360(transcript)|ensembl:ENST00000672825(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0021510"(spinal cord development)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:O75530|rcsb pdb:3IIW|rcsb pdb:3IIY|rcsb pdb:3IJ0|rcsb pdb:3IJ1|rcsb pdb:3IJC|rcsb pdb:3JPX|rcsb pdb:3JZG|rcsb pdb:3JZH|rcsb pdb:3JZN|rcsb pdb:3K26|rcsb pdb:3K27|rcsb pdb:4W2R|rcsb pdb:4X3E|rcsb pdb:5GSA|rcsb pdb:5H13|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5K0M|rcsb pdb:5LS6|rcsb pdb:5TTW|rcsb pdb:5U5H|rcsb pdb:5U5K|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5U69|rcsb pdb:5U6D|rcsb pdb:5U8A|rcsb pdb:5U8F|rcsb pdb:5WG6|rcsb pdb:5WP3|rcsb pdb:5WUK|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6SFB|rcsb pdb:6SFC|rcsb pdb:6U4Y|rcsb pdb:6V3X|rcsb pdb:6V3Y|rcsb pdb:6W7F|rcsb pdb:6W7G|rcsb pdb:6WKR|rcsb pdb:6YVI|rcsb pdb:6YVJ|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7KXT|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421 - - comment:"author score: 181" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA9606 rigid:tOJ17NgPRC/uH7LvBNRk7Du4u10 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IYD8 uniprotkb:P68363 intact:EBI-3957237|ensembl:ENSP00000267430|uniprotkb:Q3YFH9|uniprotkb:Q8N9X6|uniprotkb:Q9HCH6|uniprotkb:B2RTQ9|intact:EBI-10977447|intact:EBI-14204029|intact:EBI-12869570 intact:EBI-487083|intact:EBI-1384226|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:Q27I68|ensembl:ENSP00000336799|uniprotkb:Q8WU19 psi-mi:fancm_human(display_long)|uniprotkb:FANCM(gene name)|psi-mi:FANCM(display_short)|uniprotkb:KIAA1596(gene name synonym)|uniprotkb:ATP-dependent RNA helicase FANCM(gene name synonym)|uniprotkb:Fanconi anemia-associated polypeptide of 250 kDa(gene name synonym)|uniprotkb:Protein Hef ortholog(gene name synonym) psi-mi:tba1b_human(display_long)|uniprotkb:TUBA1B(gene name)|psi-mi:TUBA1B(display_short)|uniprotkb:Tubulin alpha-ubiquitous chain(gene name synonym)|uniprotkb:Alpha-tubulin ubiquitous(gene name synonym)|uniprotkb:Tubulin K-alpha-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478655|imex:IM-26985-467 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000187790(gene)|ensembl:ENST00000267430(transcript)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004518"(nuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0031297"(replication fork processing)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|go:"GO:0045003"(double-strand break repair via synthesis-dependent strand annealing)|go:"GO:0071821"(FANCM-MHF complex)|go:"GO:0071932"(replication fork reversal)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006166(DNA repair nuclease, XPF-type/Helicase)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR031879|interpro:IPR039686|interpro:IPR044749|mint:Q8IYD8|rcsb pdb:4DAY|rcsb pdb:4DRB|rcsb pdb:4E45|rcsb pdb:4M6W|reactome:R-HSA-6783310|rcsb pdb:4BXO|refseq:NP_001295062.1|refseq:NP_001295063.1|refseq:NP_065988.1|dip:DIP-43972N refseq:NP_006073.2|ensembl:ENSG00000123416(gene)|ensembl:ENST00000336023(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-983189|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|go:"GO:0045121"(membrane raft)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68363|rcsb pdb:2E4H|rcsb pdb:5IJ0|rcsb pdb:5IJ9|rcsb pdb:5N5N|rcsb pdb:6E7B|rcsb pdb:6E7C|rcsb pdb:6I2I|go:"GO:0051301"(cell division)|rcsb pdb:6J4V|rcsb pdb:6J8O|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|rcsb pdb:6S8L|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9013407|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-2132295|reactome:R-HSA-9668328 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:APU9Ya2dfdgJgIwZPl5Z8/QMbgM9606 rogid:D4YpuLCXl/S+53qV7P7sF81aARY9606 rigid:+1CH/M8n+J02+/RiR6YHOye6JwA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IYD8 uniprotkb:Q92688 intact:EBI-3957237|ensembl:ENSP00000267430|uniprotkb:Q3YFH9|uniprotkb:Q8N9X6|uniprotkb:Q9HCH6|uniprotkb:B2RTQ9|intact:EBI-10977447|intact:EBI-14204029|intact:EBI-12869570 intact:EBI-762428|uniprotkb:O00655|uniprotkb:P78458|uniprotkb:P78459|uniprotkb:B2R9C7|ensembl:ENSP00000345848 psi-mi:fancm_human(display_long)|uniprotkb:FANCM(gene name)|psi-mi:FANCM(display_short)|uniprotkb:KIAA1596(gene name synonym)|uniprotkb:ATP-dependent RNA helicase FANCM(gene name synonym)|uniprotkb:Fanconi anemia-associated polypeptide of 250 kDa(gene name synonym)|uniprotkb:Protein Hef ortholog(gene name synonym) psi-mi:an32b_human(display_long)|uniprotkb:Acidic protein rich in leucines(gene name synonym)|uniprotkb:Silver-stainable protein SSP29(gene name synonym)|uniprotkb:ANP32B(gene name)|psi-mi:ANP32B(display_short)|uniprotkb:APRIL(gene name synonym)|uniprotkb:PHAPI2(gene name synonym)|uniprotkb:Putative HLA-DR-associated protein I-2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478655|imex:IM-26985-467 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000187790(gene)|ensembl:ENST00000267430(transcript)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004518"(nuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0031297"(replication fork processing)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|go:"GO:0045003"(double-strand break repair via synthesis-dependent strand annealing)|go:"GO:0071821"(FANCM-MHF complex)|go:"GO:0071932"(replication fork reversal)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006166(DNA repair nuclease, XPF-type/Helicase)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR031879|interpro:IPR039686|interpro:IPR044749|mint:Q8IYD8|rcsb pdb:4DAY|rcsb pdb:4DRB|rcsb pdb:4E45|rcsb pdb:4M6W|reactome:R-HSA-6783310|rcsb pdb:4BXO|refseq:NP_001295062.1|refseq:NP_001295063.1|refseq:NP_065988.1|dip:DIP-43972N refseq:NP_006392.1|ensembl:ENSG00000136938(gene)|ensembl:ENST00000339399(transcript)|go:"GO:0001944"(vasculature development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0021591"(ventricular system development)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048839"(inner ear development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|mint:Q92688|rcsb pdb:2ELL|rcsb pdb:2RR6|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal) - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:APU9Ya2dfdgJgIwZPl5Z8/QMbgM9606 rogid:8eu0C8oHWUrZ28F2fIup9o5MDYk9606 rigid:+1CH/M8n+J02+/RiR6YHOye6JwA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IYD8 uniprotkb:P81605 intact:EBI-3957237|ensembl:ENSP00000267430|uniprotkb:Q3YFH9|uniprotkb:Q8N9X6|uniprotkb:Q9HCH6|uniprotkb:B2RTQ9|intact:EBI-10977447|intact:EBI-14204029|intact:EBI-12869570 intact:EBI-395625|uniprotkb:P58461|uniprotkb:A5JHP2|uniprotkb:A5JHP3|uniprotkb:Q53YJ2|ensembl:ENSP00000293371 psi-mi:fancm_human(display_long)|uniprotkb:FANCM(gene name)|psi-mi:FANCM(display_short)|uniprotkb:KIAA1596(gene name synonym)|uniprotkb:ATP-dependent RNA helicase FANCM(gene name synonym)|uniprotkb:Fanconi anemia-associated polypeptide of 250 kDa(gene name synonym)|uniprotkb:Protein Hef ortholog(gene name synonym) psi-mi:dcd_human(display_long)|uniprotkb:AIDD(gene name synonym)|uniprotkb:DSEP(gene name synonym)|uniprotkb:Preproteolysin(gene name synonym)|uniprotkb:DCD(gene name)|psi-mi:DCD(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478655|imex:IM-26985-467 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000187790(gene)|ensembl:ENST00000267430(transcript)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004518"(nuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0031297"(replication fork processing)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|go:"GO:0045003"(double-strand break repair via synthesis-dependent strand annealing)|go:"GO:0071821"(FANCM-MHF complex)|go:"GO:0071932"(replication fork reversal)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006166(DNA repair nuclease, XPF-type/Helicase)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR031879|interpro:IPR039686|interpro:IPR044749|mint:Q8IYD8|rcsb pdb:4DAY|rcsb pdb:4DRB|rcsb pdb:4E45|rcsb pdb:4M6W|reactome:R-HSA-6783310|rcsb pdb:4BXO|refseq:NP_001295062.1|refseq:NP_001295063.1|refseq:NP_065988.1|dip:DIP-43972N refseq:NP_444513.1|refseq:NP_001287783.1|ensembl:ENSG00000161634(gene)|ensembl:ENST00000293371(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008233"(peptidase activity)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR028130|interpro:IPR043557|mint:P81605|rcsb pdb:2KSG|rcsb pdb:2NDK|rcsb pdb:2YMK|rcsb pdb:6SHK|reactome:R-HSA-6803157 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:APU9Ya2dfdgJgIwZPl5Z8/QMbgM9606 rogid:M8PkKVWx98nhtd79ods05mqw8Ls9606 rigid:+1CH/M8n+J02+/RiR6YHOye6JwA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IYD8 uniprotkb:P07477 intact:EBI-3957237|ensembl:ENSP00000267430|uniprotkb:Q3YFH9|uniprotkb:Q8N9X6|uniprotkb:Q9HCH6|uniprotkb:B2RTQ9|intact:EBI-10977447|intact:EBI-14204029|intact:EBI-12869570 intact:EBI-1222902|uniprotkb:A6NJ71|uniprotkb:Q92955|uniprotkb:Q9HAN4|uniprotkb:Q9HAN5|uniprotkb:Q9HAN6|uniprotkb:Q9HAN7|intact:EBI-1760472|intact:EBI-1965533|uniprotkb:A1A509|uniprotkb:Q5NV57|uniprotkb:Q7M4N3|uniprotkb:Q7M4N4|uniprotkb:B2R5I5|ensembl:ENSP00000308720|ensembl:ENSP00000479217 psi-mi:fancm_human(display_long)|uniprotkb:FANCM(gene name)|psi-mi:FANCM(display_short)|uniprotkb:KIAA1596(gene name synonym)|uniprotkb:ATP-dependent RNA helicase FANCM(gene name synonym)|uniprotkb:Fanconi anemia-associated polypeptide of 250 kDa(gene name synonym)|uniprotkb:Protein Hef ortholog(gene name synonym) psi-mi:try1_human(display_long)|uniprotkb:PRSS1(gene name)|psi-mi:PRSS1(display_short)|uniprotkb:TRP1(gene name synonym)|uniprotkb:TRY1(gene name synonym)|uniprotkb:TRYP1(gene name synonym)|uniprotkb:Trypsin I(gene name synonym)|uniprotkb:Cationic trypsinogen(gene name synonym)|uniprotkb:Serine protease 1(gene name synonym)|uniprotkb:Beta-trypsin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478655|imex:IM-26985-467 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000187790(gene)|ensembl:ENST00000267430(transcript)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0003682"(chromatin binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0004518"(nuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0031297"(replication fork processing)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0043240"(Fanconi anaemia nuclear complex)|go:"GO:0045003"(double-strand break repair via synthesis-dependent strand annealing)|go:"GO:0071821"(FANCM-MHF complex)|go:"GO:0071932"(replication fork reversal)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006166(DNA repair nuclease, XPF-type/Helicase)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR031879|interpro:IPR039686|interpro:IPR044749|mint:Q8IYD8|rcsb pdb:4DAY|rcsb pdb:4DRB|rcsb pdb:4E45|rcsb pdb:4M6W|reactome:R-HSA-6783310|rcsb pdb:4BXO|refseq:NP_001295062.1|refseq:NP_001295063.1|refseq:NP_065988.1|dip:DIP-43972N refseq:NP_002760.1|ensembl:ENSG00000204983(gene)|ensembl:ENSG00000274247(gene)|ensembl:ENST00000311737(transcript)|ensembl:ENST00000616256(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0007586"(digestion)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0072562"(blood microparticle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|mint:P07477|rcsb pdb:1FXY|rcsb pdb:1TRN|rcsb pdb:2RA3|rcsb pdb:4WWY|rcsb pdb:4WXV|reactome:R-HSA-1592389|reactome:R-HSA-196741 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:APU9Ya2dfdgJgIwZPl5Z8/QMbgM9606 rogid:2elS/qMYj0sflxilyWfk3KPtGmo9606 rigid:+1CH/M8n+J02+/RiR6YHOye6JwA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6PCT2 uniprotkb:P35268 intact:EBI-6664563|ensembl:ENSP00000455529|uniprotkb:A8MT10|uniprotkb:Q8N789|uniprotkb:Q9NT14 intact:EBI-354533|intact:EBI-1055963|uniprotkb:Q6IBD1|uniprotkb:B2R495|ensembl:ENSP00000346088 psi-mi:fxl19_human(display_long)|uniprotkb:FBXL19(gene name)|psi-mi:FBXL19(display_short)|uniprotkb:FBL19(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 19(gene name synonym) psi-mi:rl22_human(display_long)|uniprotkb:RPL22(gene name)|psi-mi:RPL22(display_short)|uniprotkb:Heparin-binding protein HBp15(gene name synonym)|uniprotkb:Epstein-Barr virus small RNA-associated protein(gene name synonym)|uniprotkb:EBER-associated protein(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL22(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478673|imex:IM-26985-469 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000099364(gene)|ensembl:ENST00000562319(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045322"(unmethylated CpG binding)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|mint:Q6PCT2|rcsb pdb:6ASB|reactome:R-HSA-8951664|reactome:R-HSA-983168|interpro:IPR019786|refseq:NP_001269280.1|refseq:NP_001093254.2 refseq:NP_000974.1|ensembl:ENSG00000116251(gene)|ensembl:ENST00000234875(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0008201"(heparin binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0045182"(translation regulator activity)|go:"GO:0046632"(alpha-beta T cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099577"(regulation of translation at presynapse, modulating synaptic transmission)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002671(Ribosomal protein L22e)|interpro:IPR038526|mint:P35268|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|reactome:R-HSA-72706|rcsb pdb:6Z6L|rcsb pdb:6Z6M|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wtar4oBKcxTqx7B6RWX9BQgriVY9606 rogid:0TVillnqDkHmdTwxIedAJCVAdzY9606 rigid:R19jQ7TVl8hlEeGnm8I8YxNLZ+E false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6PCT2 uniprotkb:Q13363 intact:EBI-6664563|ensembl:ENSP00000455529|uniprotkb:A8MT10|uniprotkb:Q8N789|uniprotkb:Q9NT14 intact:EBI-908846|uniprotkb:Q4W5N3|uniprotkb:Q7Z2Q5|ensembl:ENSP00000290921 psi-mi:fxl19_human(display_long)|uniprotkb:FBXL19(gene name)|psi-mi:FBXL19(display_short)|uniprotkb:FBL19(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 19(gene name synonym) psi-mi:ctbp1_human(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478673|imex:IM-26985-469 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000099364(gene)|ensembl:ENST00000562319(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045322"(unmethylated CpG binding)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|mint:Q6PCT2|rcsb pdb:6ASB|reactome:R-HSA-8951664|reactome:R-HSA-983168|interpro:IPR019786|refseq:NP_001269280.1|refseq:NP_001093254.2 refseq:NP_001012632.1|refseq:NP_001319.1|refseq:XP_016863253.1|refseq:XP_016863254.1|refseq:XP_016863255.1|refseq:XP_016863256.1|dip:DIP-24245N|ensembl:ENSG00000159692(gene)|ensembl:ENST00000290921(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019079"(viral genome replication)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:Q13363|rcsb pdb:1MX3|rcsb pdb:4LCE|rcsb pdb:4U6Q|rcsb pdb:4U6S|rcsb pdb:6CDF|rcsb pdb:6CDR|rcsb pdb:6V89|rcsb pdb:6V8A|rcsb pdb:7KWM|reactome:R-HSA-3769402|reactome:R-HSA-3899300|reactome:R-HSA-4641265|reactome:R-HSA-5339700 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wtar4oBKcxTqx7B6RWX9BQgriVY9606 rogid:hhYGrtcr0oAQW5x5LfNmxfuRNj49606 rigid:R19jQ7TVl8hlEeGnm8I8YxNLZ+E false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6PCT2 uniprotkb:Q96RQ3 intact:EBI-6664563|ensembl:ENSP00000455529|uniprotkb:A8MT10|uniprotkb:Q8N789|uniprotkb:Q9NT14 intact:EBI-2211703|uniprotkb:Q59ES4|uniprotkb:Q9H959|uniprotkb:Q9NS97|ensembl:ENSP00000265594 psi-mi:fxl19_human(display_long)|uniprotkb:FBXL19(gene name)|psi-mi:FBXL19(display_short)|uniprotkb:FBL19(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 19(gene name synonym) psi-mi:mcca_human(display_long)|uniprotkb:MCCC1(gene name)|psi-mi:MCCC1(display_short)|uniprotkb:MCCA(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase 1(gene name synonym)|uniprotkb:"3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha"(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase biotin-containing subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478673|imex:IM-26985-469 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000099364(gene)|ensembl:ENST00000562319(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045322"(unmethylated CpG binding)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|mint:Q6PCT2|rcsb pdb:6ASB|reactome:R-HSA-8951664|reactome:R-HSA-983168|interpro:IPR019786|refseq:NP_001269280.1|refseq:NP_001093254.2 refseq:NP_064551.3|refseq:NP_001280202.1|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR016185(PreATP-grasp-like fold)|mint:Q96RQ3|rcsb pdb:2EJM|reactome:R-HSA-196780|reactome:R-HSA-3371599|reactome:R-HSA-70895|ensembl:ENSG00000078070(gene)|ensembl:ENST00000265594(transcript)|go:"GO:0002169"(3-methylcrotonyl-CoA carboxylase complex, mitochondrial)|go:"GO:0004075"(biotin carboxylase activity)|go:"GO:0004485"(methylcrotonoyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0006768"(biotin metabolic process)|go:"GO:0009374"(biotin binding)|go:"GO:0016421"(CoA carboxylase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:1905202"(methylcrotonoyl-CoA carboxylase complex)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001882(Biotin-binding site)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding) - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wtar4oBKcxTqx7B6RWX9BQgriVY9606 rogid:obze7v7i2yTIIcJjd7laIriNFg89606 rigid:R19jQ7TVl8hlEeGnm8I8YxNLZ+E false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6PCT2 uniprotkb:Q9UII2 intact:EBI-6664563|ensembl:ENSP00000455529|uniprotkb:A8MT10|uniprotkb:Q8N789|uniprotkb:Q9NT14 intact:EBI-718459|uniprotkb:Q5JXL8|uniprotkb:Q6IAQ7|uniprotkb:Q9BSL9|ensembl:ENSP00000335203|ensembl:ENSP00000494248 psi-mi:fxl19_human(display_long)|uniprotkb:FBXL19(gene name)|psi-mi:FBXL19(display_short)|uniprotkb:FBL19(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 19(gene name synonym) psi-mi:atif1_human(display_long)|uniprotkb:ATP synthase F1 subunit epsilon(gene name synonym)|uniprotkb:ATPI(gene name synonym)|uniprotkb:ATPIF1(gene name synonym)|uniprotkb:"Inhibitor of F(1)F(o)-ATPase"(gene name synonym)|uniprotkb:ATP5IF1(gene name)|psi-mi:ATP5IF1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478673|imex:IM-26985-469 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000099364(gene)|ensembl:ENST00000562319(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045322"(unmethylated CpG binding)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|mint:Q6PCT2|rcsb pdb:6ASB|reactome:R-HSA-8951664|reactome:R-HSA-983168|interpro:IPR019786|refseq:NP_001269280.1|refseq:NP_001093254.2 refseq:NP_057395.1|refseq:NP_835497.1|refseq:NP_835498.1|ensembl:ENSG00000130770(gene)|ensembl:ENSG00000285390(gene)|ensembl:ENST00000335514(transcript)|ensembl:ENST00000647074(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0009986"(cell surface)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043532"(angiostatin binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051882"(mitochondrial depolarization)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0140260"(mitochondrial proton-transporting ATP synthase complex binding)|go:"GO:1901030"(positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1903052"(positive regulation of proteolysis involved in cellular protein catabolic process)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:1903578"(regulation of ATP metabolic process)|go:"GO:1904925"(positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization)|interpro:IPR007648(Mitochondrial ATPase inhibitor, IATP)|mint:Q9UII2|go:"GO:0051346"(negative regulation of hydrolase activity) - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wtar4oBKcxTqx7B6RWX9BQgriVY9606 rogid:KLbFWln/ZxNq87OFWJRU6OzkHtc9606 rigid:R19jQ7TVl8hlEeGnm8I8YxNLZ+E false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6PCT2 uniprotkb:P23284 intact:EBI-6664563|ensembl:ENSP00000455529|uniprotkb:A8MT10|uniprotkb:Q8N789|uniprotkb:Q9NT14 intact:EBI-359252|uniprotkb:Q9BVK5|uniprotkb:A8K534|uniprotkb:Q6IBH5|ensembl:ENSP00000300026 psi-mi:fxl19_human(display_long)|uniprotkb:FBXL19(gene name)|psi-mi:FBXL19(display_short)|uniprotkb:FBL19(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 19(gene name synonym) psi-mi:ppib_human(display_long)|uniprotkb:PPIB(gene name)|psi-mi:PPIB(display_short)|uniprotkb:CYPB(gene name synonym)|uniprotkb:Cyclophilin B(gene name synonym)|uniprotkb:S-cyclophilin(gene name synonym)|uniprotkb:CYP-S1(gene name synonym)|uniprotkb:Rotamase B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478673|imex:IM-26985-469 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000099364(gene)|ensembl:ENST00000562319(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045322"(unmethylated CpG binding)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|mint:Q6PCT2|rcsb pdb:6ASB|reactome:R-HSA-8951664|reactome:R-HSA-983168|interpro:IPR019786|refseq:NP_001269280.1|refseq:NP_001093254.2 refseq:NP_000933.1|ensembl:ENSG00000166794(gene)|ensembl:ENST00000300026(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003723"(RNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016020"(membrane)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042470"(melanosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0060348"(bone development)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000|mint:P23284|rcsb pdb:1CYN|rcsb pdb:3ICH|rcsb pdb:3ICI|reactome:R-HSA-1650814 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wtar4oBKcxTqx7B6RWX9BQgriVY9606 rogid:h6nKaPUyEYUctYuu/3XfFhM4y9c9606 rigid:R19jQ7TVl8hlEeGnm8I8YxNLZ+E false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6PCT2 uniprotkb:Q9NS69 intact:EBI-6664563|ensembl:ENSP00000455529|uniprotkb:A8MT10|uniprotkb:Q8N789|uniprotkb:Q9NT14 intact:EBI-1047508|intact:EBI-1180569|ensembl:ENSP00000216034 psi-mi:fxl19_human(display_long)|uniprotkb:FBXL19(gene name)|psi-mi:FBXL19(display_short)|uniprotkb:FBL19(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 19(gene name synonym) psi-mi:tom22_human(display_long)|uniprotkb:TOMM22(gene name)|psi-mi:TOMM22(display_short)|uniprotkb:TOM22(gene name synonym)|uniprotkb:Translocase of outer membrane 22 kDa subunit homolog(gene name synonym)|uniprotkb:1C9-2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478673|imex:IM-26985-469 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000099364(gene)|ensembl:ENST00000562319(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045322"(unmethylated CpG binding)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|mint:Q6PCT2|rcsb pdb:6ASB|reactome:R-HSA-8951664|reactome:R-HSA-983168|interpro:IPR019786|refseq:NP_001269280.1|refseq:NP_001093254.2 refseq:NP_064628.1|ensembl:ENSG00000100216(gene)|ensembl:ENST00000216034(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005742"(mitochondrial outer membrane translocase complex)|go:"GO:0006626"(protein targeting to mitochondrion)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|interpro:IPR005683(Mitochondrial import translocase, subunit Tom22)|mint:Q9NS69|rcsb pdb:7CK6|rcsb pdb:7CP9|reactome:R-HSA-1268020|reactome:R-HSA-5205685 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wtar4oBKcxTqx7B6RWX9BQgriVY9606 rogid:DI3BGFSB04B1/mMHJsBpOsCxrYk9606 rigid:R19jQ7TVl8hlEeGnm8I8YxNLZ+E false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6PCT2 uniprotkb:P42126 intact:EBI-6664563|ensembl:ENSP00000455529|uniprotkb:A8MT10|uniprotkb:Q8N789|uniprotkb:Q9NT14 intact:EBI-3916545|uniprotkb:Q9UDG6|uniprotkb:Q7Z2L6|uniprotkb:Q9BUB8|uniprotkb:Q7Z2L7|uniprotkb:A8K512|uniprotkb:Q13290|uniprotkb:Q9BW05|ensembl:ENSP00000301729 psi-mi:fxl19_human(display_long)|uniprotkb:FBXL19(gene name)|psi-mi:FBXL19(display_short)|uniprotkb:FBL19(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 19(gene name synonym) psi-mi:eci1_human(display_long)|uniprotkb:ECI1(gene name)|psi-mi:ECI1(display_short)|uniprotkb:DCI(gene name synonym)|uniprotkb:3,2-trans-enoyl-CoA isomerase(gene name synonym)|uniprotkb:"Delta(3),Delta(2)-enoyl-CoA isomerase"(gene name synonym)|uniprotkb:Dodecenoyl-CoA isomerase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478673|imex:IM-26985-469 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000099364(gene)|ensembl:ENST00000562319(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045322"(unmethylated CpG binding)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|mint:Q6PCT2|rcsb pdb:6ASB|reactome:R-HSA-8951664|reactome:R-HSA-983168|interpro:IPR019786|refseq:NP_001269280.1|refseq:NP_001093254.2 refseq:NP_001171500.1|refseq:NP_001910.2|ensembl:ENSG00000167969(gene)|ensembl:ENST00000301729(transcript)|go:"GO:0004165"("delta(3)-delta(2)-enoyl-CoA isomerase activity")|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016863"(intramolecular oxidoreductase activity, transposing C=C bonds)|interpro:IPR001753(Crotonase, core)|interpro:IPR018376|mint:P42126|rcsb pdb:1SG4|reactome:R-HSA-77288|interpro:IPR029045 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wtar4oBKcxTqx7B6RWX9BQgriVY9606 rogid:2243TLwuS1/H1h7qBk/lL0DFQGI9606 rigid:R19jQ7TVl8hlEeGnm8I8YxNLZ+E false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6PCT2 uniprotkb:P09211 intact:EBI-6664563|ensembl:ENSP00000455529|uniprotkb:A8MT10|uniprotkb:Q8N789|uniprotkb:Q9NT14 intact:EBI-353467|uniprotkb:O00460|uniprotkb:Q15690|ensembl:ENSP00000381607|uniprotkb:Q5TZY3 psi-mi:fxl19_human(display_long)|uniprotkb:FBXL19(gene name)|psi-mi:FBXL19(display_short)|uniprotkb:FBL19(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 19(gene name synonym) psi-mi:gstp1_human(display_long)|uniprotkb:GSTP1(gene name)|psi-mi:GSTP1(display_short)|uniprotkb:GST3(gene name synonym)|uniprotkb:FAEES3(gene name synonym)|uniprotkb:GST class-pi(gene name synonym)|uniprotkb:GSTP1-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478673|imex:IM-26985-469 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000099364(gene)|ensembl:ENST00000562319(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045322"(unmethylated CpG binding)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|mint:Q6PCT2|rcsb pdb:6ASB|reactome:R-HSA-8951664|reactome:R-HSA-983168|interpro:IPR019786|refseq:NP_001269280.1|refseq:NP_001093254.2 refseq:NP_000843.1|ensembl:ENSG00000084207(gene)|go:"GO:0000302"(response to reactive oxygen species)|ensembl:ENST00000398606(transcript)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006693"(prostaglandin metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0009890"(negative regulation of biosynthetic process)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0019207"(kinase regulator activity)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031982"(vesicle)|go:"GO:0032355"(response to estradiol)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033591"(response to L-ascorbic acid)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035726"(common myeloid progenitor cell proliferation)|go:"GO:0035730"(S-nitrosoglutathione binding)|go:"GO:0035731"(dinitrosyl-iron complex binding)|go:"GO:0035732"(nitric oxide storage)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0043651"(linoleic acid metabolic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051122"(hepoxilin biosynthetic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003082(Glutathione S-transferase, Pi class)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|mint:P09211|rcsb pdb:10GS|rcsb pdb:11GS|rcsb pdb:12GS|rcsb pdb:13GS|rcsb pdb:14GS|rcsb pdb:16GS|rcsb pdb:17GS|rcsb pdb:18GS|rcsb pdb:19GS|rcsb pdb:1AQV|rcsb pdb:1AQW|rcsb pdb:1AQX|rcsb pdb:1EOG|rcsb pdb:1EOH|rcsb pdb:1GSS|rcsb pdb:1KBN|rcsb pdb:1LBK|rcsb pdb:1MD3|rcsb pdb:1MD4|rcsb pdb:1PGT|rcsb pdb:1PX6|rcsb pdb:1PX7|rcsb pdb:1ZGN|rcsb pdb:20GS|rcsb pdb:22GS|rcsb pdb:2A2R|rcsb pdb:2A2S|rcsb pdb:2GSS|rcsb pdb:2J9H|rcsb pdb:2PGT|rcsb pdb:3CSH|rcsb pdb:3CSI|rcsb pdb:3CSJ|rcsb pdb:3DD3|rcsb pdb:3DGQ|rcsb pdb:3GSS|rcsb pdb:3GUS|rcsb pdb:3HJM|rcsb pdb:3HJO|rcsb pdb:3HKR|rcsb pdb:3IE3|rcsb pdb:3KM6|rcsb pdb:3KMN|rcsb pdb:3KMO|rcsb pdb:3N9J|rcsb pdb:3PGT|rcsb pdb:4GSS|rcsb pdb:4PGT|rcsb pdb:5DAK|rcsb pdb:5DAL|rcsb pdb:5DCG|rcsb pdb:5DDL|rcsb pdb:5DJL|rcsb pdb:5DJM|rcsb pdb:5GSS|rcsb pdb:5J41|rcsb pdb:5JCW|rcsb pdb:5L6X|rcsb pdb:5X79|rcsb pdb:6AP9|rcsb pdb:6GSS|rcsb pdb:6LLX|rcsb pdb:6Y1E|rcsb pdb:7GSS|rcsb pdb:8GSS|rcsb pdb:9GSS|reactome:R-HSA-156590|reactome:R-HSA-3299685|reactome:R-HSA-6798695|go:"GO:0051771"(negative regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0070026"(nitric oxide binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070664"(negative regulation of leukocyte proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071460"(cellular response to cell-matrix adhesion)|go:"GO:0071638"(negative regulation of monocyte chemotactic protein-1 production)|go:"GO:0071672"(negative regulation of smooth muscle cell chemotaxis)|go:"GO:0097057"(TRAF2-GSTP1 complex)|go:"GO:1901687"(glutathione derivative biosynthetic process)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation) - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wtar4oBKcxTqx7B6RWX9BQgriVY9606 rogid:JxqbNusNIvkTg3Cq+7pmygP/EIA9606 rigid:R19jQ7TVl8hlEeGnm8I8YxNLZ+E false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6PCT2 uniprotkb:P61006 intact:EBI-6664563|ensembl:ENSP00000455529|uniprotkb:A8MT10|uniprotkb:Q8N789|uniprotkb:Q9NT14 intact:EBI-722293|intact:EBI-1054454|uniprotkb:P24407|intact:EBI-2798283|uniprotkb:Q6FHV5|uniprotkb:B4DEK7|ensembl:ENSP00000300935 psi-mi:fxl19_human(display_long)|uniprotkb:FBXL19(gene name)|psi-mi:FBXL19(display_short)|uniprotkb:FBL19(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 19(gene name synonym) psi-mi:rab8a_human(display_long)|uniprotkb:Oncogene c-mel(gene name synonym)|uniprotkb:RAB8A(gene name)|psi-mi:RAB8A(display_short)|uniprotkb:MEL(gene name synonym)|uniprotkb:RAB8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478673|imex:IM-26985-469 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000099364(gene)|ensembl:ENST00000562319(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045322"(unmethylated CpG binding)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|mint:Q6PCT2|rcsb pdb:6ASB|reactome:R-HSA-8951664|reactome:R-HSA-983168|interpro:IPR019786|refseq:NP_001269280.1|refseq:NP_001093254.2 refseq:NP_005361.2|dip:DIP-43703N|ensembl:ENSG00000167461(gene)|ensembl:ENST00000300935(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0006914"(autophagy)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0019003"(GDP binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030496"(midbody)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031489"(myosin V binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0048169"(regulation of long-term neuronal synaptic plasticity)|go:"GO:0048210"(Golgi vesicle fusion to target membrane)|go:"GO:0051223"(regulation of protein transport)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097730"(non-motile cilium)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098969"(neurotransmitter receptor transport to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099003"(vesicle-mediated transport in synapse)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P61006|rcsb pdb:3QBT|rcsb pdb:3TNF|rcsb pdb:4LHV|rcsb pdb:4LHW|rcsb pdb:4LHX|rcsb pdb:4LHY|go:"GO:0014069"(postsynaptic density)|go:"GO:0017157"(regulation of exocytosis)|rcsb pdb:4LHZ|rcsb pdb:4LI0|rcsb pdb:5SZI|rcsb pdb:6RIR|rcsb pdb:6SQ2|rcsb pdb:6STF|rcsb pdb:6STG|rcsb pdb:6WHE|rcsb pdb:6ZSI|rcsb pdb:6ZSJ|rcsb pdb:7BWT|rcsb pdb:7LWB|reactome:R-HSA-1445148|reactome:R-HSA-2565942|reactome:R-HSA-5620912|reactome:R-HSA-5620916|reactome:R-HSA-8854214|reactome:R-HSA-8873719|reactome:R-HSA-8876198 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wtar4oBKcxTqx7B6RWX9BQgriVY9606 rogid:ucWVK9e1z44F2XnAJatPYm8IRlk9606 rigid:R19jQ7TVl8hlEeGnm8I8YxNLZ+E false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6PCT2 uniprotkb:P31151 intact:EBI-6664563|ensembl:ENSP00000455529|uniprotkb:A8MT10|uniprotkb:Q8N789|uniprotkb:Q9NT14 intact:EBI-357520|uniprotkb:Q6FGE3|uniprotkb:Q5SY67|uniprotkb:Q9H1E2|ensembl:ENSP00000357711|ensembl:ENSP00000357712 psi-mi:fxl19_human(display_long)|uniprotkb:FBXL19(gene name)|psi-mi:FBXL19(display_short)|uniprotkb:FBL19(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 19(gene name synonym) psi-mi:s10a7_human(display_long)|uniprotkb:S100A7(gene name)|psi-mi:S100A7(display_short)|uniprotkb:PSOR1(gene name synonym)|uniprotkb:S100A7C(gene name synonym)|uniprotkb:S100 calcium-binding protein A7(gene name synonym)|uniprotkb:Psoriasin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478673|imex:IM-26985-469 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000099364(gene)|ensembl:ENST00000562319(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045322"(unmethylated CpG binding)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|mint:Q6PCT2|rcsb pdb:6ASB|reactome:R-HSA-8951664|reactome:R-HSA-983168|interpro:IPR019786|refseq:NP_001269280.1|refseq:NP_001093254.2 ensembl:ENSG00000143556(gene)|ensembl:ENST00000368722(transcript)|ensembl:ENST00000368723(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001525"(angiogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008544"(epidermis development)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045087"(innate immune response)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051238"(sequestering of metal ion)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071624"(positive regulation of granulocyte chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028477|interpro:IPR034325|mint:P31151|rcsb pdb:1PSR|rcsb pdb:2PSR|rcsb pdb:2WND|rcsb pdb:2WOR|rcsb pdb:2WOS|rcsb pdb:3PSR|rcsb pdb:4AQJ|reactome:R-HSA-6798695|reactome:R-HSA-6799990|refseq:NP_002954.2 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wtar4oBKcxTqx7B6RWX9BQgriVY9606 rogid:/v8+XQ7rCMTYzq9k/KqjcSm/G0A9606 rigid:R19jQ7TVl8hlEeGnm8I8YxNLZ+E false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6PCT2 uniprotkb:P14406 intact:EBI-6664563|ensembl:ENSP00000455529|uniprotkb:A8MT10|uniprotkb:Q8N789|uniprotkb:Q9NT14 intact:EBI-2606666|uniprotkb:Q5TF59|uniprotkb:Q6FGI2|uniprotkb:Q3MIH5|uniprotkb:B2R5E1|ensembl:ENSP00000506727 psi-mi:fxl19_human(display_long)|uniprotkb:FBXL19(gene name)|psi-mi:FBXL19(display_short)|uniprotkb:FBL19(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 19(gene name synonym) psi-mi:cx7a2_human(display_long)|uniprotkb:COX7AL(gene name synonym)|uniprotkb:Cytochrome c oxidase subunit VIIa-liver/heart(gene name synonym)|uniprotkb:COX7A2(gene name)|psi-mi:COX7A2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478673|imex:IM-26985-469 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000099364(gene)|ensembl:ENST00000562319(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045322"(unmethylated CpG binding)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|mint:Q6PCT2|rcsb pdb:6ASB|reactome:R-HSA-8951664|reactome:R-HSA-983168|interpro:IPR019786|refseq:NP_001269280.1|refseq:NP_001093254.2 refseq:NP_001856.2|ensembl:ENSG00000112695(gene)|ensembl:ENST00000684430(transcript)|go:"GO:0002082"(regulation of oxidative phosphorylation)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0097250"(mitochondrial respirasome assembly)|interpro:IPR003177(Cytochrome c oxidase, subunit VIIa)|interpro:IPR036539|interpro:IPR039297|mint:P14406|rcsb pdb:5Z62 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wtar4oBKcxTqx7B6RWX9BQgriVY9606 rogid:krjTK658npBV4G6gH28GJhVqBkY9606 rigid:R19jQ7TVl8hlEeGnm8I8YxNLZ+E false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6PCT2 uniprotkb:Q9HCC0 intact:EBI-6664563|ensembl:ENSP00000455529|uniprotkb:A8MT10|uniprotkb:Q8N789|uniprotkb:Q9NT14 intact:EBI-2211296|uniprotkb:A6NIY9|uniprotkb:Q96C27|uniprotkb:Q9Y4L7|ensembl:ENSP00000343657 psi-mi:fxl19_human(display_long)|uniprotkb:FBXL19(gene name)|psi-mi:FBXL19(display_short)|uniprotkb:FBL19(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 19(gene name synonym) psi-mi:mccb_human(display_long)|uniprotkb:MCCC2(gene name)|psi-mi:MCCC2(display_short)|uniprotkb:MCCB(gene name synonym)|uniprotkb:"3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta"(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478673|imex:IM-26985-469 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000099364(gene)|ensembl:ENST00000562319(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045322"(unmethylated CpG binding)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|mint:Q6PCT2|rcsb pdb:6ASB|reactome:R-HSA-8951664|reactome:R-HSA-983168|interpro:IPR019786|refseq:NP_001269280.1|refseq:NP_001093254.2 refseq:NP_071415.1|refseq:XP_005248624.1|ensembl:ENSG00000131844(gene)|ensembl:ENST00000340941(transcript)|go:"GO:0002169"(3-methylcrotonyl-CoA carboxylase complex, mitochondrial)|go:"GO:0004485"(methylcrotonoyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:1905202"(methylcrotonoyl-CoA carboxylase complex)|interpro:IPR011762(Acetyl-coenzyme A carboxyltransferase, N-terminal)|interpro:IPR011763(Acetyl-coenzyme A carboxyltransferase, C-terminal)|interpro:IPR029045|interpro:IPR034733|mint:Q9HCC0|reactome:R-HSA-196780|reactome:R-HSA-3371599|reactome:R-HSA-70895 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wtar4oBKcxTqx7B6RWX9BQgriVY9606 rogid:5NkqDKqdX1wHsbqXW7v5+/Gld109606 rigid:R19jQ7TVl8hlEeGnm8I8YxNLZ+E false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6PCT2 uniprotkb:P18077 intact:EBI-6664563|ensembl:ENSP00000455529|uniprotkb:A8MT10|uniprotkb:Q8N789|uniprotkb:Q9NT14 intact:EBI-353383|uniprotkb:Q08ES9|uniprotkb:Q9BVN7|ensembl:ENSP00000393393|ensembl:ENSP00000495672 psi-mi:fxl19_human(display_long)|uniprotkb:FBXL19(gene name)|psi-mi:FBXL19(display_short)|uniprotkb:FBL19(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 19(gene name synonym) psi-mi:rl35a_human(display_long)|uniprotkb:RPL35A(gene name)|psi-mi:RPL35A(display_short)|uniprotkb:Cell growth-inhibiting gene 33 protein(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL33(gene name synonym)|uniprotkb:GIG33(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478673|imex:IM-26985-469 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000099364(gene)|ensembl:ENST00000562319(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045322"(unmethylated CpG binding)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|mint:Q6PCT2|rcsb pdb:6ASB|reactome:R-HSA-8951664|reactome:R-HSA-983168|interpro:IPR019786|refseq:NP_001269280.1|refseq:NP_001093254.2 refseq:NP_000987.2|refseq:NP_001303240.1|ensembl:ENST00000647248(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001780(Ribosomal protein L35Ae)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR018266|interpro:IPR038661|mint:P18077|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|ensembl:ENSG00000182899(gene)|ensembl:ENST00000448864(transcript)|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wtar4oBKcxTqx7B6RWX9BQgriVY9606 rogid:fnUlL17LsiOp3lSkKNsoYO74IQQ9606 rigid:R19jQ7TVl8hlEeGnm8I8YxNLZ+E false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6PCT2 uniprotkb:P06702 intact:EBI-6664563|ensembl:ENSP00000455529|uniprotkb:A8MT10|uniprotkb:Q8N789|uniprotkb:Q9NT14 intact:EBI-1055001|uniprotkb:Q6FGA1|uniprotkb:Q9NYM0|uniprotkb:Q9UCJ1|uniprotkb:D3DV36|ensembl:ENSP00000357727 psi-mi:fxl19_human(display_long)|uniprotkb:FBXL19(gene name)|psi-mi:FBXL19(display_short)|uniprotkb:FBL19(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 19(gene name synonym) psi-mi:s10a9_human(display_long)|uniprotkb:S100 calcium-binding protein A9(gene name synonym)|uniprotkb:Calgranulin-B(gene name synonym)|uniprotkb:Migration inhibitory factor-related protein 14(gene name synonym)|uniprotkb:Leukocyte L1 complex heavy chain(gene name synonym)|uniprotkb:Calprotectin L1H subunit(gene name synonym)|uniprotkb:S100A9(gene name)|psi-mi:S100A9(display_short)|uniprotkb:CAGB(gene name synonym)|uniprotkb:CFAG(gene name synonym)|uniprotkb:MRP14(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478673|imex:IM-26985-469 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000099364(gene)|ensembl:ENST00000562319(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045322"(unmethylated CpG binding)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|mint:Q6PCT2|rcsb pdb:6ASB|reactome:R-HSA-8951664|reactome:R-HSA-983168|interpro:IPR019786|refseq:NP_001269280.1|refseq:NP_001093254.2 refseq:NP_002956.1|rcsb pdb:1XK4|rcsb pdb:4GGF|rcsb pdb:4XJK|rcsb pdb:5I8N|rcsb pdb:5W1F|rcsb pdb:6DS2|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5668599|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-6799990|ensembl:ENSG00000163220(gene)|ensembl:ENST00000368738(transcript)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035662"(Toll-like receptor 4 binding)|go:"GO:0035821"(modulation of process of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0045113"(regulation of integrin biosynthetic process)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070488"(neutrophil aggregation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|mint:P06702|rcsb pdb:1IRJ|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016209"(antioxidant activity)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0030054"(cell junction)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032119"(sequestering of zinc ion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035425"(autocrine signaling)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|dip:DIP-1166N - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wtar4oBKcxTqx7B6RWX9BQgriVY9606 rogid:IGnX4DSnv8xMr5pY4T7X7vYos5A9606 rigid:R19jQ7TVl8hlEeGnm8I8YxNLZ+E false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6PCT2 uniprotkb:P61604 intact:EBI-6664563|ensembl:ENSP00000455529|uniprotkb:A8MT10|uniprotkb:Q8N789|uniprotkb:Q9NT14 intact:EBI-711483|uniprotkb:O95421|uniprotkb:Q04984|uniprotkb:Q53X54|ensembl:ENSP00000233893|uniprotkb:Q9UDH0 psi-mi:fxl19_human(display_long)|uniprotkb:FBXL19(gene name)|psi-mi:FBXL19(display_short)|uniprotkb:FBL19(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 19(gene name synonym) psi-mi:ch10_human(display_long)|uniprotkb:HSPE1(gene name)|psi-mi:HSPE1(display_short)|uniprotkb:10 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 10(gene name synonym)|uniprotkb:Early-pregnancy factor(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478673|imex:IM-26985-469 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000099364(gene)|ensembl:ENST00000562319(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045322"(unmethylated CpG binding)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|mint:Q6PCT2|rcsb pdb:6ASB|reactome:R-HSA-8951664|reactome:R-HSA-983168|interpro:IPR019786|refseq:NP_001269280.1|refseq:NP_001093254.2 interpro:IPR020818|interpro:IPR037124|mint:P61604|rcsb pdb:4PJ1|rcsb pdb:6HT7|rcsb pdb:6MRC|rcsb pdb:6MRD|reactome:R-HSA-9013408|ensembl:ENSG00000115541(gene)|ensembl:ENST00000233893(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR011032(GroES-like)|interpro:IPR018369|refseq:NP_002148.1 - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wtar4oBKcxTqx7B6RWX9BQgriVY9606 rogid:BmnGoMnA2QIr3Dr0fElMtTgRztA9606 rigid:R19jQ7TVl8hlEeGnm8I8YxNLZ+E false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6PCT2 uniprotkb:P61289 intact:EBI-6664563|ensembl:ENSP00000455529|uniprotkb:A8MT10|uniprotkb:Q8N789|uniprotkb:Q9NT14 intact:EBI-355546|uniprotkb:O35563|uniprotkb:P97373|uniprotkb:Q12920|uniprotkb:Q13172|uniprotkb:Q9BQD9|uniprotkb:A8K9A3|ensembl:ENSP00000466794 psi-mi:fxl19_human(display_long)|uniprotkb:FBXL19(gene name)|psi-mi:FBXL19(display_short)|uniprotkb:FBL19(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 19(gene name synonym) psi-mi:psme3_human(display_long)|uniprotkb:PSME3(gene name)|psi-mi:PSME3(display_short)|uniprotkb:Proteasome activator 28 subunit gamma(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 3(gene name synonym)|uniprotkb:11S regulator complex subunit gamma(gene name synonym)|uniprotkb:Ki nuclear autoantigen(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478673|imex:IM-26985-469 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000099364(gene)|ensembl:ENST00000562319(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045322"(unmethylated CpG binding)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|mint:Q6PCT2|rcsb pdb:6ASB|reactome:R-HSA-8951664|reactome:R-HSA-983168|interpro:IPR019786|refseq:NP_001269280.1|refseq:NP_001093254.2 refseq:NP_005780.2|refseq:NP_789839.1|ensembl:ENSG00000131467(gene)|ensembl:ENST00000590720(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008537"(proteasome activator complex)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:P61289|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 - - comment:"author score: 40" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wtar4oBKcxTqx7B6RWX9BQgriVY9606 rogid:6EQY2Kj3Juf++m4eBDzPWMgbC2k9606 rigid:R19jQ7TVl8hlEeGnm8I8YxNLZ+E false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6PCT2 uniprotkb:P63208 intact:EBI-6664563|ensembl:ENSP00000455529|uniprotkb:A8MT10|uniprotkb:Q8N789|uniprotkb:Q9NT14 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 psi-mi:fxl19_human(display_long)|uniprotkb:FBXL19(gene name)|psi-mi:FBXL19(display_short)|uniprotkb:FBL19(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 19(gene name synonym) psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478673|imex:IM-26985-469 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000099364(gene)|ensembl:ENST00000562319(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045322"(unmethylated CpG binding)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|mint:Q6PCT2|rcsb pdb:6ASB|reactome:R-HSA-8951664|reactome:R-HSA-983168|interpro:IPR019786|refseq:NP_001269280.1|refseq:NP_001093254.2 reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N - - comment:"author score: 68" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wtar4oBKcxTqx7B6RWX9BQgriVY9606 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rigid:R19jQ7TVl8hlEeGnm8I8YxNLZ+E false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P49354 uniprotkb:P53609 intact:EBI-602336|uniprotkb:Q9UDC1|uniprotkb:A6NJW0|uniprotkb:Q53XJ9|ensembl:ENSP00000303423 intact:EBI-8456634|intact:MINT-3019919|uniprotkb:Q5MJP9|ensembl:ENSP00000404676 psi-mi:fnta_human(display_long)|uniprotkb:CAAX farnesyltransferase subunit alpha(gene name synonym)|uniprotkb:Ras proteins prenyltransferase subunit alpha(gene name synonym)|uniprotkb:FTase-alpha(gene name synonym)|uniprotkb:Type I protein geranyl-geranyltransferase subunit alpha(gene name synonym)|uniprotkb:FNTA(gene name)|psi-mi:FNTA(display_short) psi-mi:pgtb1_human(display_long)|uniprotkb:PGGT1B(gene name)|psi-mi:PGGT1B(display_short)|uniprotkb:Geranylgeranyl transferase type I subunit beta(gene name synonym)|uniprotkb:Type I protein geranyl-geranyltransferase subunit beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478730|imex:IM-26985-395 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002018.1|ensembl:ENSG00000168522(gene)|ensembl:ENST00000302279(transcript)|go:"GO:0004660"(protein farnesyltransferase activity)|go:"GO:0004661"(protein geranylgeranyltransferase activity)|go:"GO:0004662"(CAAX-protein geranylgeranyltransferase activity)|go:"GO:0004663"(Rab geranylgeranyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005953"(CAAX-protein geranylgeranyltransferase complex)|go:"GO:0005965"(protein farnesyltransferase complex)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0018343"(protein farnesylation)|go:"GO:0018344"(protein geranylgeranylation)|go:"GO:0030548"(acetylcholine receptor regulator activity)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0090044"(positive regulation of tubulin deacetylation)|go:"GO:0090045"(positive regulation of deacetylase activity)|interpro:IPR002088(Protein prenyltransferase, alpha subunit)|mint:P49354|rcsb pdb:1JCQ|rcsb pdb:1LD7|rcsb pdb:1LD8|rcsb pdb:1MZC|rcsb pdb:1S63|rcsb pdb:1SA4|rcsb pdb:1TN6|rcsb pdb:2F0Y|rcsb pdb:2H6F|rcsb pdb:2H6G|rcsb pdb:2H6H|rcsb pdb:2H6I|rcsb pdb:2IEJ|rcsb pdb:3E37|reactome:R-HSA-111465|reactome:R-HSA-2514859|reactome:R-HSA-9648002 refseq:NP_005014.2|ensembl:ENSG00000164219(gene)|ensembl:ENST00000419445(transcript)|go:"GO:0004661"(protein geranylgeranyltransferase activity)|go:"GO:0004662"(CAAX-protein geranylgeranyltransferase activity)|go:"GO:0005953"(CAAX-protein geranylgeranyltransferase complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0018342"(protein prenylation)|go:"GO:0018344"(protein geranylgeranylation)|go:"GO:0034097"(response to cytokine)|go:"GO:0036094"(small molecule binding)|go:"GO:0042277"(peptide binding)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0051771"(negative regulation of nitric-oxide synthase biosynthetic process)|interpro:IPR001330(Prenyltransferase/squalene oxidase)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR041960|mint:P53609 - - function:Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to a cysteine at the fourth position from the C-terminus of proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. Acts on the Rac1, Rac2, Rap1A and Rap1B proteins. The beta subunit is responsible for peptide-binding|comment:"author score: 147" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:2VOoFRlMYQR1v9oiOKl1sktjaa09606 rogid:35Q6RXumW+f41SJvpn9E6Kwa/AU9606 rigid:bMN62VjwhlHnpdLyz86wCwbhPoU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P49354 uniprotkb:Q9Y6H1 intact:EBI-602336|uniprotkb:Q9UDC1|uniprotkb:A6NJW0|uniprotkb:Q53XJ9|ensembl:ENSP00000303423 intact:EBI-2321769|uniprotkb:Q498C3|uniprotkb:Q6NZ50|ensembl:ENSP00000378812 psi-mi:fnta_human(display_long)|uniprotkb:CAAX farnesyltransferase subunit alpha(gene name synonym)|uniprotkb:Ras proteins prenyltransferase subunit alpha(gene name synonym)|uniprotkb:FTase-alpha(gene name synonym)|uniprotkb:Type I protein geranyl-geranyltransferase subunit alpha(gene name synonym)|uniprotkb:FNTA(gene name)|psi-mi:FNTA(display_short) psi-mi:chch2_human(display_long)|uniprotkb:CHCHD2(gene name)|psi-mi:CHCHD2(display_short)|uniprotkb:C7orf17(gene name synonym)|uniprotkb:HCV NS2 trans-regulated protein(gene name synonym)|uniprotkb:Aging-associated gene 10 protein(gene name synonym)|uniprotkb:AAG10(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478730|imex:IM-26985-395 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002018.1|ensembl:ENSG00000168522(gene)|ensembl:ENST00000302279(transcript)|go:"GO:0004660"(protein farnesyltransferase activity)|go:"GO:0004661"(protein geranylgeranyltransferase activity)|go:"GO:0004662"(CAAX-protein geranylgeranyltransferase activity)|go:"GO:0004663"(Rab geranylgeranyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005953"(CAAX-protein geranylgeranyltransferase complex)|go:"GO:0005965"(protein farnesyltransferase complex)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0018343"(protein farnesylation)|go:"GO:0018344"(protein geranylgeranylation)|go:"GO:0030548"(acetylcholine receptor regulator activity)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0090044"(positive regulation of tubulin deacetylation)|go:"GO:0090045"(positive regulation of deacetylase activity)|interpro:IPR002088(Protein prenyltransferase, alpha subunit)|mint:P49354|rcsb pdb:1JCQ|rcsb pdb:1LD7|rcsb pdb:1LD8|rcsb pdb:1MZC|rcsb pdb:1S63|rcsb pdb:1SA4|rcsb pdb:1TN6|rcsb pdb:2F0Y|rcsb pdb:2H6F|rcsb pdb:2H6G|rcsb pdb:2H6H|rcsb pdb:2H6I|rcsb pdb:2IEJ|rcsb pdb:3E37|reactome:R-HSA-111465|reactome:R-HSA-2514859|reactome:R-HSA-9648002 refseq:NP_057223.1|ensembl:ENSG00000106153(gene)|ensembl:ENST00000395422(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900037"(regulation of cellular response to hypoxia)|go:"GO:1905448"(positive regulation of mitochondrial ATP synthesis coupled electron transport)|interpro:IPR010625(CHCH)|mint:Q9Y6H1|reactome:R-HSA-1268020 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:2VOoFRlMYQR1v9oiOKl1sktjaa09606 rogid:fdx3lE51+yZ1k3uwh8/LDKJC+CQ9606 rigid:bMN62VjwhlHnpdLyz86wCwbhPoU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P49354 uniprotkb:P62736 intact:EBI-602336|uniprotkb:Q9UDC1|uniprotkb:A6NJW0|uniprotkb:Q53XJ9|ensembl:ENSP00000303423 intact:EBI-698810|uniprotkb:P03996|uniprotkb:P04108|uniprotkb:Q6FI19|uniprotkb:B2R8A4|ensembl:ENSP00000224784 psi-mi:fnta_human(display_long)|uniprotkb:CAAX farnesyltransferase subunit alpha(gene name synonym)|uniprotkb:Ras proteins prenyltransferase subunit alpha(gene name synonym)|uniprotkb:FTase-alpha(gene name synonym)|uniprotkb:Type I protein geranyl-geranyltransferase subunit alpha(gene name synonym)|uniprotkb:FNTA(gene name)|psi-mi:FNTA(display_short) psi-mi:acta_human(display_long)|uniprotkb:Alpha-actin-2(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 46 protein(gene name synonym)|uniprotkb:ACTA2(gene name)|psi-mi:ACTA2(display_short)|uniprotkb:ACTSA(gene name synonym)|uniprotkb:ACTVS(gene name synonym)|uniprotkb:GIG46(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478730|imex:IM-26985-395 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002018.1|ensembl:ENSG00000168522(gene)|ensembl:ENST00000302279(transcript)|go:"GO:0004660"(protein farnesyltransferase activity)|go:"GO:0004661"(protein geranylgeranyltransferase activity)|go:"GO:0004662"(CAAX-protein geranylgeranyltransferase activity)|go:"GO:0004663"(Rab geranylgeranyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005953"(CAAX-protein geranylgeranyltransferase complex)|go:"GO:0005965"(protein farnesyltransferase complex)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0018343"(protein farnesylation)|go:"GO:0018344"(protein geranylgeranylation)|go:"GO:0030548"(acetylcholine receptor regulator activity)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0090044"(positive regulation of tubulin deacetylation)|go:"GO:0090045"(positive regulation of deacetylase activity)|interpro:IPR002088(Protein prenyltransferase, alpha subunit)|mint:P49354|rcsb pdb:1JCQ|rcsb pdb:1LD7|rcsb pdb:1LD8|rcsb pdb:1MZC|rcsb pdb:1S63|rcsb pdb:1SA4|rcsb pdb:1TN6|rcsb pdb:2F0Y|rcsb pdb:2H6F|rcsb pdb:2H6G|rcsb pdb:2H6H|rcsb pdb:2H6I|rcsb pdb:2IEJ|rcsb pdb:3E37|reactome:R-HSA-111465|reactome:R-HSA-2514859|reactome:R-HSA-9648002 refseq:NP_001135417.1|refseq:NP_001604.1|refseq:NP_001307784.1|ensembl:ENSG00000107796(gene)|ensembl:ENST00000224784(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014829"(vascular associated smooth muscle contraction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030485"(smooth muscle contractile fiber)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072144"(glomerular mesangial cell development)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P62736|reactome:R-HSA-445355|reactome:R-HSA-9013695 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:2VOoFRlMYQR1v9oiOKl1sktjaa09606 rogid:mRZGUdL/jBuj6nVHtxoasZuA7yA9606 rigid:bMN62VjwhlHnpdLyz86wCwbhPoU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P49354 uniprotkb:P49354 intact:EBI-602336|uniprotkb:Q9UDC1|uniprotkb:A6NJW0|uniprotkb:Q53XJ9|ensembl:ENSP00000303423 intact:EBI-602336|uniprotkb:Q9UDC1|uniprotkb:A6NJW0|uniprotkb:Q53XJ9|ensembl:ENSP00000303423 psi-mi:fnta_human(display_long)|uniprotkb:CAAX farnesyltransferase subunit alpha(gene name synonym)|uniprotkb:Ras proteins prenyltransferase subunit alpha(gene name synonym)|uniprotkb:FTase-alpha(gene name synonym)|uniprotkb:Type I protein geranyl-geranyltransferase subunit alpha(gene name synonym)|uniprotkb:FNTA(gene name)|psi-mi:FNTA(display_short) psi-mi:fnta_human(display_long)|uniprotkb:CAAX farnesyltransferase subunit alpha(gene name synonym)|uniprotkb:Ras proteins prenyltransferase subunit alpha(gene name synonym)|uniprotkb:FTase-alpha(gene name synonym)|uniprotkb:Type I protein geranyl-geranyltransferase subunit alpha(gene name synonym)|uniprotkb:FNTA(gene name)|psi-mi:FNTA(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478730|imex:IM-26985-395 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002018.1|ensembl:ENSG00000168522(gene)|ensembl:ENST00000302279(transcript)|go:"GO:0004660"(protein farnesyltransferase activity)|go:"GO:0004661"(protein geranylgeranyltransferase activity)|go:"GO:0004662"(CAAX-protein geranylgeranyltransferase activity)|go:"GO:0004663"(Rab geranylgeranyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005953"(CAAX-protein geranylgeranyltransferase complex)|go:"GO:0005965"(protein farnesyltransferase complex)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0018343"(protein farnesylation)|go:"GO:0018344"(protein geranylgeranylation)|go:"GO:0030548"(acetylcholine receptor regulator activity)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0090044"(positive regulation of tubulin deacetylation)|go:"GO:0090045"(positive regulation of deacetylase activity)|interpro:IPR002088(Protein prenyltransferase, alpha subunit)|mint:P49354|rcsb pdb:1JCQ|rcsb pdb:1LD7|rcsb pdb:1LD8|rcsb pdb:1MZC|rcsb pdb:1S63|rcsb pdb:1SA4|rcsb pdb:1TN6|rcsb pdb:2F0Y|rcsb pdb:2H6F|rcsb pdb:2H6G|rcsb pdb:2H6H|rcsb pdb:2H6I|rcsb pdb:2IEJ|rcsb pdb:3E37|reactome:R-HSA-111465|reactome:R-HSA-2514859|reactome:R-HSA-9648002 refseq:NP_002018.1|ensembl:ENSG00000168522(gene)|ensembl:ENST00000302279(transcript)|go:"GO:0004660"(protein farnesyltransferase activity)|go:"GO:0004661"(protein geranylgeranyltransferase activity)|go:"GO:0004662"(CAAX-protein geranylgeranyltransferase activity)|go:"GO:0004663"(Rab geranylgeranyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005953"(CAAX-protein geranylgeranyltransferase complex)|go:"GO:0005965"(protein farnesyltransferase complex)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0018343"(protein farnesylation)|go:"GO:0018344"(protein geranylgeranylation)|go:"GO:0030548"(acetylcholine receptor regulator activity)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0090044"(positive regulation of tubulin deacetylation)|go:"GO:0090045"(positive regulation of deacetylase activity)|interpro:IPR002088(Protein prenyltransferase, alpha subunit)|mint:P49354|rcsb pdb:1JCQ|rcsb pdb:1LD7|rcsb pdb:1LD8|rcsb pdb:1MZC|rcsb pdb:1S63|rcsb pdb:1SA4|rcsb pdb:1TN6|rcsb pdb:2F0Y|rcsb pdb:2H6F|rcsb pdb:2H6G|rcsb pdb:2H6H|rcsb pdb:2H6I|rcsb pdb:2IEJ|rcsb pdb:3E37|reactome:R-HSA-111465|reactome:R-HSA-2514859|reactome:R-HSA-9648002 - - comment:"author score: 301" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:2VOoFRlMYQR1v9oiOKl1sktjaa09606 rogid:2VOoFRlMYQR1v9oiOKl1sktjaa09606 rigid:bMN62VjwhlHnpdLyz86wCwbhPoU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P49354 uniprotkb:Q9Y6H1 intact:EBI-602336|uniprotkb:Q9UDC1|uniprotkb:A6NJW0|uniprotkb:Q53XJ9|ensembl:ENSP00000303423 intact:EBI-2321769|uniprotkb:Q498C3|uniprotkb:Q6NZ50|ensembl:ENSP00000378812 psi-mi:fnta_human(display_long)|uniprotkb:CAAX farnesyltransferase subunit alpha(gene name synonym)|uniprotkb:Ras proteins prenyltransferase subunit alpha(gene name synonym)|uniprotkb:FTase-alpha(gene name synonym)|uniprotkb:Type I protein geranyl-geranyltransferase subunit alpha(gene name synonym)|uniprotkb:FNTA(gene name)|psi-mi:FNTA(display_short) psi-mi:chch2_human(display_long)|uniprotkb:CHCHD2(gene name)|psi-mi:CHCHD2(display_short)|uniprotkb:C7orf17(gene name synonym)|uniprotkb:HCV NS2 trans-regulated protein(gene name synonym)|uniprotkb:Aging-associated gene 10 protein(gene name synonym)|uniprotkb:AAG10(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478730|imex:IM-26985-395 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002018.1|ensembl:ENSG00000168522(gene)|ensembl:ENST00000302279(transcript)|go:"GO:0004660"(protein farnesyltransferase activity)|go:"GO:0004661"(protein geranylgeranyltransferase activity)|go:"GO:0004662"(CAAX-protein geranylgeranyltransferase activity)|go:"GO:0004663"(Rab geranylgeranyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005953"(CAAX-protein geranylgeranyltransferase complex)|go:"GO:0005965"(protein farnesyltransferase complex)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0018343"(protein farnesylation)|go:"GO:0018344"(protein geranylgeranylation)|go:"GO:0030548"(acetylcholine receptor regulator activity)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0090044"(positive regulation of tubulin deacetylation)|go:"GO:0090045"(positive regulation of deacetylase activity)|interpro:IPR002088(Protein prenyltransferase, alpha subunit)|mint:P49354|rcsb pdb:1JCQ|rcsb pdb:1LD7|rcsb pdb:1LD8|rcsb pdb:1MZC|rcsb pdb:1S63|rcsb pdb:1SA4|rcsb pdb:1TN6|rcsb pdb:2F0Y|rcsb pdb:2H6F|rcsb pdb:2H6G|rcsb pdb:2H6H|rcsb pdb:2H6I|rcsb pdb:2IEJ|rcsb pdb:3E37|reactome:R-HSA-111465|reactome:R-HSA-2514859|reactome:R-HSA-9648002 refseq:NP_057223.1|ensembl:ENSG00000106153(gene)|ensembl:ENST00000395422(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900037"(regulation of cellular response to hypoxia)|go:"GO:1905448"(positive regulation of mitochondrial ATP synthesis coupled electron transport)|interpro:IPR010625(CHCH)|mint:Q9Y6H1|reactome:R-HSA-1268020 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:2VOoFRlMYQR1v9oiOKl1sktjaa09606 rogid:fdx3lE51+yZ1k3uwh8/LDKJC+CQ9606 rigid:bMN62VjwhlHnpdLyz86wCwbhPoU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P49354 uniprotkb:Q8NCN4 intact:EBI-602336|uniprotkb:Q9UDC1|uniprotkb:A6NJW0|uniprotkb:Q53XJ9|ensembl:ENSP00000303423 intact:EBI-6380946|ensembl:ENSP00000299563|uniprotkb:Q6N015 psi-mi:fnta_human(display_long)|uniprotkb:CAAX farnesyltransferase subunit alpha(gene name synonym)|uniprotkb:Ras proteins prenyltransferase subunit alpha(gene name synonym)|uniprotkb:FTase-alpha(gene name synonym)|uniprotkb:Type I protein geranyl-geranyltransferase subunit alpha(gene name synonym)|uniprotkb:FNTA(gene name)|psi-mi:FNTA(display_short) psi-mi:rn169_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase RNF169(gene name synonym)|uniprotkb:RNF169(gene name)|psi-mi:RNF169(display_short)|uniprotkb:KIAA1991(gene name synonym)|uniprotkb:RING finger protein 169(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478730|imex:IM-26985-395 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002018.1|ensembl:ENSG00000168522(gene)|ensembl:ENST00000302279(transcript)|go:"GO:0004660"(protein farnesyltransferase activity)|go:"GO:0004661"(protein geranylgeranyltransferase activity)|go:"GO:0004662"(CAAX-protein geranylgeranyltransferase activity)|go:"GO:0004663"(Rab geranylgeranyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005953"(CAAX-protein geranylgeranyltransferase complex)|go:"GO:0005965"(protein farnesyltransferase complex)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0018343"(protein farnesylation)|go:"GO:0018344"(protein geranylgeranylation)|go:"GO:0030548"(acetylcholine receptor regulator activity)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0090044"(positive regulation of tubulin deacetylation)|go:"GO:0090045"(positive regulation of deacetylase activity)|interpro:IPR002088(Protein prenyltransferase, alpha subunit)|mint:P49354|rcsb pdb:1JCQ|rcsb pdb:1LD7|rcsb pdb:1LD8|rcsb pdb:1MZC|rcsb pdb:1S63|rcsb pdb:1SA4|rcsb pdb:1TN6|rcsb pdb:2F0Y|rcsb pdb:2H6F|rcsb pdb:2H6G|rcsb pdb:2H6H|rcsb pdb:2H6I|rcsb pdb:2IEJ|rcsb pdb:3E37|reactome:R-HSA-111465|reactome:R-HSA-2514859|reactome:R-HSA-9648002 ensembl:ENSG00000166439(gene)|ensembl:ENST00000299563(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016740"(transferase activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:2000780"(negative regulation of double-strand break repair)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|mint:Q8NCN4|go:"GO:0005634"(nucleus)|rcsb pdb:5GG4|rcsb pdb:5VEY|refseq:NP_001092108.1 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:2VOoFRlMYQR1v9oiOKl1sktjaa09606 rogid:4WxnE/HtelF6yE2NC8YXDBn+sa09606 rigid:bMN62VjwhlHnpdLyz86wCwbhPoU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P49354 uniprotkb:Q7Z7K6 intact:EBI-602336|uniprotkb:Q9UDC1|uniprotkb:A6NJW0|uniprotkb:Q53XJ9|ensembl:ENSP00000303423 intact:EBI-1210604|uniprotkb:Q3L8N5|uniprotkb:Q8NFH6|uniprotkb:B2RPK2 psi-mi:fnta_human(display_long)|uniprotkb:CAAX farnesyltransferase subunit alpha(gene name synonym)|uniprotkb:Ras proteins prenyltransferase subunit alpha(gene name synonym)|uniprotkb:FTase-alpha(gene name synonym)|uniprotkb:Type I protein geranyl-geranyltransferase subunit alpha(gene name synonym)|uniprotkb:FNTA(gene name)|psi-mi:FNTA(display_short) psi-mi:cenpv_human(display_long)|uniprotkb:CENPV(gene name)|psi-mi:CENPV(display_short)|uniprotkb:Nuclear protein p30(gene name synonym)|uniprotkb:PRR6(gene name synonym)|uniprotkb:Proline-rich protein 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478730|imex:IM-26985-395 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002018.1|ensembl:ENSG00000168522(gene)|ensembl:ENST00000302279(transcript)|go:"GO:0004660"(protein farnesyltransferase activity)|go:"GO:0004661"(protein geranylgeranyltransferase activity)|go:"GO:0004662"(CAAX-protein geranylgeranyltransferase activity)|go:"GO:0004663"(Rab geranylgeranyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005953"(CAAX-protein geranylgeranyltransferase complex)|go:"GO:0005965"(protein farnesyltransferase complex)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0018343"(protein farnesylation)|go:"GO:0018344"(protein geranylgeranylation)|go:"GO:0030548"(acetylcholine receptor regulator activity)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0090044"(positive regulation of tubulin deacetylation)|go:"GO:0090045"(positive regulation of deacetylase activity)|interpro:IPR002088(Protein prenyltransferase, alpha subunit)|mint:P49354|rcsb pdb:1JCQ|rcsb pdb:1LD7|rcsb pdb:1LD8|rcsb pdb:1MZC|rcsb pdb:1S63|rcsb pdb:1SA4|rcsb pdb:1TN6|rcsb pdb:2F0Y|rcsb pdb:2H6F|rcsb pdb:2H6G|rcsb pdb:2H6H|rcsb pdb:2H6I|rcsb pdb:2IEJ|rcsb pdb:3E37|reactome:R-HSA-111465|reactome:R-HSA-2514859|reactome:R-HSA-9648002 refseq:NP_859067.2|interpro:IPR006913(Glutathione-dependent formaldehyde-activating, GFA)|interpro:IPR011057(Mss4-like)|mint:Q7Z7K6|go:"GO:0000776"(kinetochore)|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016846"(carbon-sulfur lyase activity)|go:"GO:0030496"(midbody)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0033044"(regulation of chromosome organization)|go:"GO:0034508"(centromere complex assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0005829"(cytosol) - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:2VOoFRlMYQR1v9oiOKl1sktjaa09606 rogid:q2Dt9PEcUigyqjqFMVm3dxk54B09606 rigid:bMN62VjwhlHnpdLyz86wCwbhPoU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P49354 uniprotkb:P30405 intact:EBI-602336|uniprotkb:Q9UDC1|uniprotkb:A6NJW0|uniprotkb:Q53XJ9|ensembl:ENSP00000303423 intact:EBI-5544229|uniprotkb:Q2YDB7|uniprotkb:Q5W131|ensembl:ENSP00000225174 psi-mi:fnta_human(display_long)|uniprotkb:CAAX farnesyltransferase subunit alpha(gene name synonym)|uniprotkb:Ras proteins prenyltransferase subunit alpha(gene name synonym)|uniprotkb:FTase-alpha(gene name synonym)|uniprotkb:Type I protein geranyl-geranyltransferase subunit alpha(gene name synonym)|uniprotkb:FNTA(gene name)|psi-mi:FNTA(display_short) psi-mi:ppif_human(display_long)|uniprotkb:PPIF(gene name)|psi-mi:PPIF(display_short)|uniprotkb:CYP3(gene name synonym)|uniprotkb:Cyclophilin F(gene name synonym)|uniprotkb:Rotamase F(gene name synonym)|uniprotkb:Cyclophilin D(gene name synonym)|uniprotkb:Mitochondrial cyclophilin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478730|imex:IM-26985-395 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002018.1|ensembl:ENSG00000168522(gene)|ensembl:ENST00000302279(transcript)|go:"GO:0004660"(protein farnesyltransferase activity)|go:"GO:0004661"(protein geranylgeranyltransferase activity)|go:"GO:0004662"(CAAX-protein geranylgeranyltransferase activity)|go:"GO:0004663"(Rab geranylgeranyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005953"(CAAX-protein geranylgeranyltransferase complex)|go:"GO:0005965"(protein farnesyltransferase complex)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0018343"(protein farnesylation)|go:"GO:0018344"(protein geranylgeranylation)|go:"GO:0030548"(acetylcholine receptor regulator activity)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0090044"(positive regulation of tubulin deacetylation)|go:"GO:0090045"(positive regulation of deacetylase activity)|interpro:IPR002088(Protein prenyltransferase, alpha subunit)|mint:P49354|rcsb pdb:1JCQ|rcsb pdb:1LD7|rcsb pdb:1LD8|rcsb pdb:1MZC|rcsb pdb:1S63|rcsb pdb:1SA4|rcsb pdb:1TN6|rcsb pdb:2F0Y|rcsb pdb:2H6F|rcsb pdb:2H6G|rcsb pdb:2H6H|rcsb pdb:2H6I|rcsb pdb:2IEJ|rcsb pdb:3E37|reactome:R-HSA-111465|reactome:R-HSA-2514859|reactome:R-HSA-9648002 refseq:NP_005720.1|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010849"(regulation of proton-transporting ATPase activity, rotational mechanism)|go:"GO:0010939"(regulation of necrotic cell death)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016020"(membrane)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0070266"(necroptotic process)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071243"(cellular response to arsenic-containing substance)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0090324"(negative regulation of oxidative phosphorylation)|go:"GO:1902445"(regulation of mitochondrial membrane permeability involved in programmed necrotic cell death)|go:"GO:1902686"(mitochondrial outer membrane permeabilization involved in programmed cell death)|go:"GO:2000276"(negative regulation of oxidative phosphorylation uncoupler activity)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000|mint:P30405|rcsb pdb:2BIT|rcsb pdb:2BIU|rcsb pdb:2Z6W|rcsb pdb:3QYU|rcsb pdb:3R49|rcsb pdb:3R4G|rcsb pdb:3R54|rcsb pdb:3R56|rcsb pdb:3R57|rcsb pdb:3R59|rcsb pdb:3RCF|rcsb pdb:3RCG|rcsb pdb:3RCI|rcsb pdb:3RCK|rcsb pdb:3RCL|rcsb pdb:3RD9|rcsb pdb:3RDA|rcsb pdb:3RDB|rcsb pdb:3RDC|rcsb pdb:4J58|rcsb pdb:4J59|rcsb pdb:4J5A|rcsb pdb:4J5B|rcsb pdb:4J5C|rcsb pdb:4J5D|rcsb pdb:4J5E|rcsb pdb:4O8H|rcsb pdb:4O8I|rcsb pdb:4XNC|rcsb pdb:4ZSC|rcsb pdb:4ZSD|rcsb pdb:5A0E|rcsb pdb:5CBT|rcsb pdb:5CBU|rcsb pdb:5CBV|rcsb pdb:5CBW|rcsb pdb:5CCN|rcsb pdb:5CCQ|rcsb pdb:5CCR|rcsb pdb:5CCS|rcsb pdb:6R8L|rcsb pdb:6R8O|rcsb pdb:6R8W|rcsb pdb:6R9S|rcsb pdb:6R9U|rcsb pdb:6R9X|rcsb pdb:6RA1|rcsb pdb:6Y3E|rcsb pdb:6YBM|ensembl:ENSG00000108179(gene)|ensembl:ENST00000225174(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0002931"(response to ischemia)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding) - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:2VOoFRlMYQR1v9oiOKl1sktjaa09606 rogid:5sa9mIaCM/Fo9PA4NgA1p4c4WIg9606 rigid:bMN62VjwhlHnpdLyz86wCwbhPoU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P49354 uniprotkb:Q13627 intact:EBI-602336|uniprotkb:Q9UDC1|uniprotkb:A6NJW0|uniprotkb:Q53XJ9|ensembl:ENSP00000303423 intact:EBI-1053596|uniprotkb:O60769|uniprotkb:Q92582|uniprotkb:Q92810|uniprotkb:Q9UNM5|ensembl:ENSP00000381932|ensembl:ENSP00000494544 psi-mi:fnta_human(display_long)|uniprotkb:CAAX farnesyltransferase subunit alpha(gene name synonym)|uniprotkb:Ras proteins prenyltransferase subunit alpha(gene name synonym)|uniprotkb:FTase-alpha(gene name synonym)|uniprotkb:Type I protein geranyl-geranyltransferase subunit alpha(gene name synonym)|uniprotkb:FNTA(gene name)|psi-mi:FNTA(display_short) psi-mi:dyr1a_human(display_long)|uniprotkb:Protein kinase minibrain homolog(gene name synonym)|uniprotkb:HP86(gene name synonym)|uniprotkb:Dual specificity YAK1-related kinase(gene name synonym)|uniprotkb:DYRK1A(gene name)|psi-mi:DYRK1A(display_short)|uniprotkb:DYRK(gene name synonym)|uniprotkb:MNB(gene name synonym)|uniprotkb:MNBH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478730|imex:IM-26985-395 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002018.1|ensembl:ENSG00000168522(gene)|ensembl:ENST00000302279(transcript)|go:"GO:0004660"(protein farnesyltransferase activity)|go:"GO:0004661"(protein geranylgeranyltransferase activity)|go:"GO:0004662"(CAAX-protein geranylgeranyltransferase activity)|go:"GO:0004663"(Rab geranylgeranyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005953"(CAAX-protein geranylgeranyltransferase complex)|go:"GO:0005965"(protein farnesyltransferase complex)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0018343"(protein farnesylation)|go:"GO:0018344"(protein geranylgeranylation)|go:"GO:0030548"(acetylcholine receptor regulator activity)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0090044"(positive regulation of tubulin deacetylation)|go:"GO:0090045"(positive regulation of deacetylase activity)|interpro:IPR002088(Protein prenyltransferase, alpha subunit)|mint:P49354|rcsb pdb:1JCQ|rcsb pdb:1LD7|rcsb pdb:1LD8|rcsb pdb:1MZC|rcsb pdb:1S63|rcsb pdb:1SA4|rcsb pdb:1TN6|rcsb pdb:2F0Y|rcsb pdb:2H6F|rcsb pdb:2H6G|rcsb pdb:2H6H|rcsb pdb:2H6I|rcsb pdb:2IEJ|rcsb pdb:3E37|reactome:R-HSA-111465|reactome:R-HSA-2514859|reactome:R-HSA-9648002 refseq:NP_001387.2|refseq:NP_567824.1|refseq:NP_569120.1|refseq:NP_569122.1|refseq:XP_011527785.1|refseq:XP_006724039.1|refseq:XP_006724040.1|refseq:XP_006724041.1|ensembl:ENSG00000157540(gene)|ensembl:ENST00000398960(transcript)|ensembl:ENST00000644942(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003779"(actin binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007399"(nervous system development)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031115"(negative regulation of microtubule polymerization)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034205"(amyloid-beta formation)|go:"GO:0036289"(peptidyl-serine autophosphorylation)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043621"(protein self-association)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048156"(tau protein binding)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0090312"(positive regulation of protein deacetylation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028318|interpro:IPR044131|mint:Q13627|rcsb pdb:2VX3|rcsb pdb:2WO6|rcsb pdb:3ANQ|rcsb pdb:3ANR|rcsb pdb:4AZE|rcsb pdb:4MQ1|rcsb pdb:4MQ2|rcsb pdb:4NCT|rcsb pdb:4YLJ|rcsb pdb:4YLK|rcsb pdb:4YLL|rcsb pdb:4YU2|rcsb pdb:5A3X|rcsb pdb:5A4E|rcsb pdb:5A4L|rcsb pdb:5A4Q|rcsb pdb:5A4T|rcsb pdb:5A54|rcsb pdb:5AIK|rcsb pdb:6A1G|rcsb pdb:6EIF|rcsb pdb:6EIJ|rcsb pdb:6EIL|rcsb pdb:6EIP|rcsb pdb:6EIQ|rcsb pdb:6EIR|rcsb pdb:6EIS|rcsb pdb:6EIV|rcsb pdb:6EJ4|rcsb pdb:6QU2|rcsb pdb:6S11|rcsb pdb:6S14|rcsb pdb:6S17|rcsb pdb:6S1B|rcsb pdb:6S1H|rcsb pdb:6S1I|rcsb pdb:6S1J|rcsb pdb:6T6A|rcsb pdb:6UIP|rcsb pdb:6UWY|rcsb pdb:6YF8|rcsb pdb:7A4O|rcsb pdb:7A4R|rcsb pdb:7A4S|rcsb pdb:7A4W|rcsb pdb:7A4Z|rcsb pdb:7A51|rcsb pdb:7A52|rcsb pdb:7A53|rcsb pdb:7A55|rcsb pdb:7A5B|rcsb pdb:7A5D|rcsb pdb:7A5L|rcsb pdb:7A5N|rcsb pdb:7AJ2|rcsb pdb:7AJ4|rcsb pdb:7AJ5|rcsb pdb:7AJ7|rcsb pdb:7AJ8|rcsb pdb:7AJA|rcsb pdb:7AJM|rcsb pdb:7AJS|rcsb pdb:7AJV|rcsb pdb:7AJW|rcsb pdb:7AJY|rcsb pdb:7AK2|rcsb pdb:7AKA|rcsb pdb:7AKB|rcsb pdb:7AKE|rcsb pdb:7AKL|reactome:R-HSA-1538133|rcsb pdb:6A1F|refseq:XP_016883773.1|refseq:NP_001334650.1|refseq:NP_001334651.1|dip:DIP-39750N - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:2VOoFRlMYQR1v9oiOKl1sktjaa09606 rogid:1Y5lOF9SszLsUVauAnydhzUh7fM9606 rigid:bMN62VjwhlHnpdLyz86wCwbhPoU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P49354 uniprotkb:P56182 intact:EBI-602336|uniprotkb:Q9UDC1|uniprotkb:A6NJW0|uniprotkb:Q53XJ9|ensembl:ENSP00000303423 intact:EBI-2880285|ensembl:ENSP00000417464|uniprotkb:Q9NST5 psi-mi:fnta_human(display_long)|uniprotkb:CAAX farnesyltransferase subunit alpha(gene name synonym)|uniprotkb:Ras proteins prenyltransferase subunit alpha(gene name synonym)|uniprotkb:FTase-alpha(gene name synonym)|uniprotkb:Type I protein geranyl-geranyltransferase subunit alpha(gene name synonym)|uniprotkb:FNTA(gene name)|psi-mi:FNTA(display_short) psi-mi:rrp1_human(display_long)|uniprotkb:RRP1(gene name)|psi-mi:RRP1(display_short)|uniprotkb:D21S2056E(gene name synonym)|uniprotkb:NNP1(gene name synonym)|uniprotkb:NOP52(gene name synonym)|uniprotkb:RRP1A(gene name synonym)|uniprotkb:Novel nuclear protein 1(gene name synonym)|uniprotkb:Nucleolar protein Nop52(gene name synonym)|uniprotkb:RRP1-like protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478730|imex:IM-26985-395 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002018.1|ensembl:ENSG00000168522(gene)|ensembl:ENST00000302279(transcript)|go:"GO:0004660"(protein farnesyltransferase activity)|go:"GO:0004661"(protein geranylgeranyltransferase activity)|go:"GO:0004662"(CAAX-protein geranylgeranyltransferase activity)|go:"GO:0004663"(Rab geranylgeranyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005953"(CAAX-protein geranylgeranyltransferase complex)|go:"GO:0005965"(protein farnesyltransferase complex)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0018343"(protein farnesylation)|go:"GO:0018344"(protein geranylgeranylation)|go:"GO:0030548"(acetylcholine receptor regulator activity)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0090044"(positive regulation of tubulin deacetylation)|go:"GO:0090045"(positive regulation of deacetylase activity)|interpro:IPR002088(Protein prenyltransferase, alpha subunit)|mint:P49354|rcsb pdb:1JCQ|rcsb pdb:1LD7|rcsb pdb:1LD8|rcsb pdb:1MZC|rcsb pdb:1S63|rcsb pdb:1SA4|rcsb pdb:1TN6|rcsb pdb:2F0Y|rcsb pdb:2H6F|rcsb pdb:2H6G|rcsb pdb:2H6H|rcsb pdb:2H6I|rcsb pdb:2IEJ|rcsb pdb:3E37|reactome:R-HSA-111465|reactome:R-HSA-2514859|reactome:R-HSA-9648002 ensembl:ENSG00000160214(gene)|ensembl:ENST00000497547(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|interpro:IPR010301(Nucleolar, Nop52)|mint:P56182|reactome:R-HSA-6791226|refseq:NP_003674.1 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:2VOoFRlMYQR1v9oiOKl1sktjaa09606 rogid:Soi88HwcPgF0DZiSK8fwKkslHGI9606 rigid:bMN62VjwhlHnpdLyz86wCwbhPoU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P49354 uniprotkb:Q8IUF8 intact:EBI-602336|uniprotkb:Q9UDC1|uniprotkb:A6NJW0|uniprotkb:Q53XJ9|ensembl:ENSP00000303423 intact:EBI-751580|uniprotkb:Q6AHW4|uniprotkb:Q6SKS0|uniprotkb:Q8IU69|uniprotkb:Q8IUF6|uniprotkb:Q8IUF7|uniprotkb:Q96KB0|uniprotkb:Q96C17|uniprotkb:D3DN35|ensembl:ENSP00000328251|ensembl:ENSP00000377748 psi-mi:fnta_human(display_long)|uniprotkb:CAAX farnesyltransferase subunit alpha(gene name synonym)|uniprotkb:Ras proteins prenyltransferase subunit alpha(gene name synonym)|uniprotkb:FTase-alpha(gene name synonym)|uniprotkb:Type I protein geranyl-geranyltransferase subunit alpha(gene name synonym)|uniprotkb:FNTA(gene name)|psi-mi:FNTA(display_short) psi-mi:riox2_human(display_long)|uniprotkb:RIOX2(gene name)|psi-mi:RIOX2(display_short)|uniprotkb:60S ribosomal protein L27a histidine hydroxylase(gene name synonym)|uniprotkb:Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA(gene name synonym)|uniprotkb:Histone lysine demethylase MINA(gene name synonym)|uniprotkb:MDIG(gene name synonym)|uniprotkb:MINA(gene name synonym)|uniprotkb:MINA53(gene name synonym)|uniprotkb:MYC-induced nuclear antigen(gene name synonym)|uniprotkb:Mineral dust-induced gene protein(gene name synonym)|uniprotkb:NO52(gene name synonym)|uniprotkb:Nucleolar protein 52(gene name synonym)|uniprotkb:Ribosomal oxygenase MINA(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478730|imex:IM-26985-395 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002018.1|ensembl:ENSG00000168522(gene)|ensembl:ENST00000302279(transcript)|go:"GO:0004660"(protein farnesyltransferase activity)|go:"GO:0004661"(protein geranylgeranyltransferase activity)|go:"GO:0004662"(CAAX-protein geranylgeranyltransferase activity)|go:"GO:0004663"(Rab geranylgeranyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005953"(CAAX-protein geranylgeranyltransferase complex)|go:"GO:0005965"(protein farnesyltransferase complex)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0018343"(protein farnesylation)|go:"GO:0018344"(protein geranylgeranylation)|go:"GO:0030548"(acetylcholine receptor regulator activity)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0090044"(positive regulation of tubulin deacetylation)|go:"GO:0090045"(positive regulation of deacetylase activity)|interpro:IPR002088(Protein prenyltransferase, alpha subunit)|mint:P49354|rcsb pdb:1JCQ|rcsb pdb:1LD7|rcsb pdb:1LD8|rcsb pdb:1MZC|rcsb pdb:1S63|rcsb pdb:1SA4|rcsb pdb:1TN6|rcsb pdb:2F0Y|rcsb pdb:2H6F|rcsb pdb:2H6G|rcsb pdb:2H6H|rcsb pdb:2H6I|rcsb pdb:2IEJ|rcsb pdb:3E37|reactome:R-HSA-111465|reactome:R-HSA-2514859|reactome:R-HSA-9648002 refseq:NP_001035998.1|refseq:NP_116167.3|refseq:NP_694822.2|refseq:NP_001248758.1|refseq:XP_005247895.1|dip:DIP-28141N|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR039994|mint:Q8IUF8|rcsb pdb:2XDV|rcsb pdb:4BU2|rcsb pdb:4BXF|reactome:R-HSA-3214842|ensembl:ENSG00000170854(gene)|ensembl:ENST00000333396(transcript)|ensembl:ENST00000394198(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity) - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:2VOoFRlMYQR1v9oiOKl1sktjaa09606 rogid:tdjUsv9EuHn+AADASjfGu9U15Xc9606 rigid:bMN62VjwhlHnpdLyz86wCwbhPoU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P49354 uniprotkb:Q99873 intact:EBI-602336|uniprotkb:Q9UDC1|uniprotkb:A6NJW0|uniprotkb:Q53XJ9|ensembl:ENSP00000303423 intact:EBI-78738|intact:EBI-949313|uniprotkb:A0A087X1W2|uniprotkb:H7C2I1|uniprotkb:Q15529|uniprotkb:Q99872|uniprotkb:Q99874|uniprotkb:Q9NZ04|uniprotkb:Q9NZ05|uniprotkb:Q9NZ06|ensembl:ENSP00000406162|intact:EBI-2622582|uniprotkb:B4E3C3|uniprotkb:G5E9B6|uniprotkb:Q8WUW5|uniprotkb:Q2VP93|uniprotkb:Q6LEU5|intact:EBI-11034520|intact:EBI-6137914 psi-mi:fnta_human(display_long)|uniprotkb:CAAX farnesyltransferase subunit alpha(gene name synonym)|uniprotkb:Ras proteins prenyltransferase subunit alpha(gene name synonym)|uniprotkb:FTase-alpha(gene name synonym)|uniprotkb:Type I protein geranyl-geranyltransferase subunit alpha(gene name synonym)|uniprotkb:FNTA(gene name)|psi-mi:FNTA(display_short) psi-mi:anm1_human(display_long)|uniprotkb:PRMT1(gene name)|psi-mi:PRMT1(display_short)|uniprotkb:Interferon receptor 1-bound protein 4(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT1(gene name synonym)|uniprotkb:HMT2(gene name synonym)|uniprotkb:HRMT1L2(gene name synonym)|uniprotkb:IR1B4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478730|imex:IM-26985-395 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002018.1|ensembl:ENSG00000168522(gene)|ensembl:ENST00000302279(transcript)|go:"GO:0004660"(protein farnesyltransferase activity)|go:"GO:0004661"(protein geranylgeranyltransferase activity)|go:"GO:0004662"(CAAX-protein geranylgeranyltransferase activity)|go:"GO:0004663"(Rab geranylgeranyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005953"(CAAX-protein geranylgeranyltransferase complex)|go:"GO:0005965"(protein farnesyltransferase complex)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0018343"(protein farnesylation)|go:"GO:0018344"(protein geranylgeranylation)|go:"GO:0030548"(acetylcholine receptor regulator activity)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0090044"(positive regulation of tubulin deacetylation)|go:"GO:0090045"(positive regulation of deacetylase activity)|interpro:IPR002088(Protein prenyltransferase, alpha subunit)|mint:P49354|rcsb pdb:1JCQ|rcsb pdb:1LD7|rcsb pdb:1LD8|rcsb pdb:1MZC|rcsb pdb:1S63|rcsb pdb:1SA4|rcsb pdb:1TN6|rcsb pdb:2F0Y|rcsb pdb:2H6F|rcsb pdb:2H6G|rcsb pdb:2H6H|rcsb pdb:2H6I|rcsb pdb:2IEJ|rcsb pdb:3E37|reactome:R-HSA-111465|reactome:R-HSA-2514859|reactome:R-HSA-9648002 ensembl:ENSG00000126457(gene)|ensembl:ENST00000454376(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008170"(N-methyltransferase activity)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0034709"(methylosome)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048273"(mitogen-activated protein kinase p38 binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051260"(protein homooligomerization)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR025799|interpro:IPR029063|interpro:IPR041698|mint:Q99873|rcsb pdb:6NT2|reactome:R-HSA-3214858|reactome:R-HSA-6804114|reactome:R-HSA-8936459|reactome:R-HSA-9009391|reactome:R-HSA-9018519|refseq:NP_001527.3|refseq:NP_938074.2|refseq:XP_016882223.1|refseq:XP_016882224.1|refseq:NP_001193971.1|dip:DIP-30878N - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:2VOoFRlMYQR1v9oiOKl1sktjaa09606 rogid:8I7isKQC9YJTBzPz1Qve4V8l8Xg9606 rigid:bMN62VjwhlHnpdLyz86wCwbhPoU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P49356 uniprotkb:Q9Y6H1 intact:EBI-602349|uniprotkb:B2RDX6|uniprotkb:B4E1A0|ensembl:ENSP00000246166 intact:EBI-2321769|uniprotkb:Q498C3|uniprotkb:Q6NZ50|ensembl:ENSP00000378812 psi-mi:fntb_human(display_long)|uniprotkb:CAAX farnesyltransferase subunit beta(gene name synonym)|uniprotkb:Ras proteins prenyltransferase subunit beta(gene name synonym)|uniprotkb:FNTB(gene name)|psi-mi:FNTB(display_short) psi-mi:chch2_human(display_long)|uniprotkb:CHCHD2(gene name)|psi-mi:CHCHD2(display_short)|uniprotkb:C7orf17(gene name synonym)|uniprotkb:HCV NS2 trans-regulated protein(gene name synonym)|uniprotkb:Aging-associated gene 10 protein(gene name synonym)|uniprotkb:AAG10(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478772|imex:IM-26985-397 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002019.1|refseq:NP_001189487.1|ensembl:ENSG00000257365(gene)|ensembl:ENST00000246166(transcript)|go:"GO:0004660"(protein farnesyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0018342"(protein prenylation)|go:"GO:0018343"(protein farnesylation)|interpro:IPR001330(Prenyltransferase/squalene oxidase)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR026872|mint:P49356|rcsb pdb:1JCQ|rcsb pdb:1LD7|rcsb pdb:1LD8|rcsb pdb:1MZC|rcsb pdb:1S63|rcsb pdb:1SA4|rcsb pdb:1TN6|rcsb pdb:2F0Y|rcsb pdb:2H6F|rcsb pdb:2H6G|rcsb pdb:2H6H|rcsb pdb:2H6I|rcsb pdb:2IEJ|rcsb pdb:3E37|reactome:R-HSA-2514859|reactome:R-HSA-9648002|go:"GO:0005965"(protein farnesyltransferase complex) refseq:NP_057223.1|ensembl:ENSG00000106153(gene)|ensembl:ENST00000395422(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900037"(regulation of cellular response to hypoxia)|go:"GO:1905448"(positive regulation of mitochondrial ATP synthesis coupled electron transport)|interpro:IPR010625(CHCH)|mint:Q9Y6H1|reactome:R-HSA-1268020 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ye1bL25dNbpl0e1solLbDb5CaX49606 rogid:fdx3lE51+yZ1k3uwh8/LDKJC+CQ9606 rigid:thgevLK0CngWyw90oNaFxRtgVIk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P49356 uniprotkb:P62736 intact:EBI-602349|uniprotkb:B2RDX6|uniprotkb:B4E1A0|ensembl:ENSP00000246166 intact:EBI-698810|uniprotkb:P03996|uniprotkb:P04108|uniprotkb:Q6FI19|uniprotkb:B2R8A4|ensembl:ENSP00000224784 psi-mi:fntb_human(display_long)|uniprotkb:CAAX farnesyltransferase subunit beta(gene name synonym)|uniprotkb:Ras proteins prenyltransferase subunit beta(gene name synonym)|uniprotkb:FNTB(gene name)|psi-mi:FNTB(display_short) psi-mi:acta_human(display_long)|uniprotkb:Alpha-actin-2(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 46 protein(gene name synonym)|uniprotkb:ACTA2(gene name)|psi-mi:ACTA2(display_short)|uniprotkb:ACTSA(gene name synonym)|uniprotkb:ACTVS(gene name synonym)|uniprotkb:GIG46(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478772|imex:IM-26985-397 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002019.1|refseq:NP_001189487.1|ensembl:ENSG00000257365(gene)|ensembl:ENST00000246166(transcript)|go:"GO:0004660"(protein farnesyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0018342"(protein prenylation)|go:"GO:0018343"(protein farnesylation)|interpro:IPR001330(Prenyltransferase/squalene oxidase)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR026872|mint:P49356|rcsb pdb:1JCQ|rcsb pdb:1LD7|rcsb pdb:1LD8|rcsb pdb:1MZC|rcsb pdb:1S63|rcsb pdb:1SA4|rcsb pdb:1TN6|rcsb pdb:2F0Y|rcsb pdb:2H6F|rcsb pdb:2H6G|rcsb pdb:2H6H|rcsb pdb:2H6I|rcsb pdb:2IEJ|rcsb pdb:3E37|reactome:R-HSA-2514859|reactome:R-HSA-9648002|go:"GO:0005965"(protein farnesyltransferase complex) refseq:NP_001135417.1|refseq:NP_001604.1|refseq:NP_001307784.1|ensembl:ENSG00000107796(gene)|ensembl:ENST00000224784(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014829"(vascular associated smooth muscle contraction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030485"(smooth muscle contractile fiber)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072144"(glomerular mesangial cell development)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P62736|reactome:R-HSA-445355|reactome:R-HSA-9013695 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ye1bL25dNbpl0e1solLbDb5CaX49606 rogid:mRZGUdL/jBuj6nVHtxoasZuA7yA9606 rigid:thgevLK0CngWyw90oNaFxRtgVIk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P49356 uniprotkb:P49354 intact:EBI-602349|uniprotkb:B2RDX6|uniprotkb:B4E1A0|ensembl:ENSP00000246166 intact:EBI-602336|uniprotkb:Q9UDC1|uniprotkb:A6NJW0|uniprotkb:Q53XJ9|ensembl:ENSP00000303423 psi-mi:fntb_human(display_long)|uniprotkb:CAAX farnesyltransferase subunit beta(gene name synonym)|uniprotkb:Ras proteins prenyltransferase subunit beta(gene name synonym)|uniprotkb:FNTB(gene name)|psi-mi:FNTB(display_short) psi-mi:fnta_human(display_long)|uniprotkb:CAAX farnesyltransferase subunit alpha(gene name synonym)|uniprotkb:Ras proteins prenyltransferase subunit alpha(gene name synonym)|uniprotkb:FTase-alpha(gene name synonym)|uniprotkb:Type I protein geranyl-geranyltransferase subunit alpha(gene name synonym)|uniprotkb:FNTA(gene name)|psi-mi:FNTA(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478772|imex:IM-26985-397 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002019.1|refseq:NP_001189487.1|ensembl:ENSG00000257365(gene)|ensembl:ENST00000246166(transcript)|go:"GO:0004660"(protein farnesyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0018342"(protein prenylation)|go:"GO:0018343"(protein farnesylation)|interpro:IPR001330(Prenyltransferase/squalene oxidase)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR026872|mint:P49356|rcsb pdb:1JCQ|rcsb pdb:1LD7|rcsb pdb:1LD8|rcsb pdb:1MZC|rcsb pdb:1S63|rcsb pdb:1SA4|rcsb pdb:1TN6|rcsb pdb:2F0Y|rcsb pdb:2H6F|rcsb pdb:2H6G|rcsb pdb:2H6H|rcsb pdb:2H6I|rcsb pdb:2IEJ|rcsb pdb:3E37|reactome:R-HSA-2514859|reactome:R-HSA-9648002|go:"GO:0005965"(protein farnesyltransferase complex) refseq:NP_002018.1|ensembl:ENSG00000168522(gene)|ensembl:ENST00000302279(transcript)|go:"GO:0004660"(protein farnesyltransferase activity)|go:"GO:0004661"(protein geranylgeranyltransferase activity)|go:"GO:0004662"(CAAX-protein geranylgeranyltransferase activity)|go:"GO:0004663"(Rab geranylgeranyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005953"(CAAX-protein geranylgeranyltransferase complex)|go:"GO:0005965"(protein farnesyltransferase complex)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0018343"(protein farnesylation)|go:"GO:0018344"(protein geranylgeranylation)|go:"GO:0030548"(acetylcholine receptor regulator activity)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0090044"(positive regulation of tubulin deacetylation)|go:"GO:0090045"(positive regulation of deacetylase activity)|interpro:IPR002088(Protein prenyltransferase, alpha subunit)|mint:P49354|rcsb pdb:1JCQ|rcsb pdb:1LD7|rcsb pdb:1LD8|rcsb pdb:1MZC|rcsb pdb:1S63|rcsb pdb:1SA4|rcsb pdb:1TN6|rcsb pdb:2F0Y|rcsb pdb:2H6F|rcsb pdb:2H6G|rcsb pdb:2H6H|rcsb pdb:2H6I|rcsb pdb:2IEJ|rcsb pdb:3E37|reactome:R-HSA-111465|reactome:R-HSA-2514859|reactome:R-HSA-9648002 - - comment:"author score: 301" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ye1bL25dNbpl0e1solLbDb5CaX49606 rogid:2VOoFRlMYQR1v9oiOKl1sktjaa09606 rigid:thgevLK0CngWyw90oNaFxRtgVIk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P81605 uniprotkb:Q96NE9 intact:EBI-395625|uniprotkb:P58461|uniprotkb:A5JHP2|uniprotkb:A5JHP3|uniprotkb:Q53YJ2|ensembl:ENSP00000293371 intact:EBI-741729|uniprotkb:Q5HYF2|uniprotkb:Q8N2X1|uniprotkb:Q8WUH7|uniprotkb:D3DSB9|ensembl:ENSP00000343899 psi-mi:dcd_human(display_long)|uniprotkb:AIDD(gene name synonym)|uniprotkb:DSEP(gene name synonym)|uniprotkb:Preproteolysin(gene name synonym)|uniprotkb:DCD(gene name)|psi-mi:DCD(display_short) psi-mi:frmd6_human(display_long)|uniprotkb:Willin(gene name synonym)|uniprotkb:FRMD6(gene name)|psi-mi:FRMD6(display_short)|uniprotkb:C14orf31(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25478787|imex:IM-26985-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_444513.1|refseq:NP_001287783.1|ensembl:ENSG00000161634(gene)|ensembl:ENST00000293371(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008233"(peptidase activity)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR028130|interpro:IPR043557|mint:P81605|rcsb pdb:2KSG|rcsb pdb:2NDK|rcsb pdb:2YMK|rcsb pdb:6SHK|reactome:R-HSA-6803157 refseq:NP_001035946.1|refseq:NP_689543.1|ensembl:ENSG00000139926(gene)|ensembl:ENST00000344768(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|go:"GO:0031032"(actomyosin structure organization)|interpro:IPR040179|interpro:IPR041781|mint:Q96NE9|refseq:XP_011534725.1|refseq:XP_011534726.1|refseq:NP_001253975.1|refseq:NP_001253976.1|refseq:XP_006720092.1|refseq:XP_006720093.1 - comment:"author score: 12" - figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:M8PkKVWx98nhtd79ods05mqw8Ls9606 rogid:+lFyfyxd9BU6GDZBrAiW1Ar/L4c9606 rigid:nQ1mtLxzAcJYVnng6h6iqZWJQA4 false - tandem tag:n-n - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P51114 uniprotkb:Q86SQ7 intact:EBI-713291|uniprotkb:A8K9B8|uniprotkb:Q7Z450|uniprotkb:Q8N6R8|ensembl:ENSP00000350170 intact:EBI-1047850|uniprotkb:Q3ZCR6|uniprotkb:Q8N5F2|uniprotkb:Q9P0F1|uniprotkb:O60527|ensembl:ENSP00000355499|ensembl:ENSP00000483550 psi-mi:fxr1_human(display_long)|uniprotkb:FXR1(gene name)|psi-mi:FXR1(display_short) psi-mi:sdcg8_human(display_long)|uniprotkb:Antigen NY-CO-8(gene name synonym)|uniprotkb:Centrosomal colon cancer autoantigen protein(gene name synonym)|uniprotkb:SDCCAG8(gene name)|psi-mi:SDCCAG8(display_short)|uniprotkb:CCCAP(gene name synonym)|uniprotkb:NPHP10(gene name synonym)|uniprotkb:HSPC085(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478796|imex:IM-26985-471 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001013456.1|refseq:NP_001013457.1|refseq:NP_005078.2|go:"GO:0007517"(muscle organ development)|ensembl:ENSG00000114416(gene)|ensembl:ENST00000357559(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0060538"(skeletal muscle organ development)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR032177|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|go:"GO:0014069"(postsynaptic density)|rcsb pdb:2CPQ|rcsb pdb:3KUF|rcsb pdb:3O8V|reactome:R-HSA-6802952|mint:P51114|dip:DIP-40789N refseq:NP_006633.1|ensembl:ENSG00000054282(gene)|ensembl:ENSG00000276111(gene)|ensembl:ENST00000366541(transcript)|ensembl:ENST00000622598(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007098"(centrosome cycle)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030030"(cell projection organization)|go:"GO:0031023"(microtubule organizing center organization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035148"(tube formation)|go:"GO:0036064"(ciliary basal body)|go:"GO:0097733"(photoreceptor cell cilium)|go:"GO:1902017"(regulation of cilium assembly)|interpro:IPR031887|mint:Q86SQ7|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:XP_005273080.1 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pUW5/sakWOiRtZpigPhEMOPJBpk9606 rogid:Z3ynDtbmAV7usLzKH+M3Ilf6Ebw9606 rigid:wale3C23TeFqu4xo5MoaqjVVSZg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P51114 uniprotkb:P51116 intact:EBI-713291|uniprotkb:A8K9B8|uniprotkb:Q7Z450|uniprotkb:Q8N6R8|ensembl:ENSP00000350170 intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113 psi-mi:fxr1_human(display_long)|uniprotkb:FXR1(gene name)|psi-mi:FXR1(display_short) psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478796|imex:IM-26985-471 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001013456.1|refseq:NP_001013457.1|refseq:NP_005078.2|go:"GO:0007517"(muscle organ development)|ensembl:ENSG00000114416(gene)|ensembl:ENST00000357559(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0060538"(skeletal muscle organ development)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR032177|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|go:"GO:0014069"(postsynaptic density)|rcsb pdb:2CPQ|rcsb pdb:3KUF|rcsb pdb:3O8V|reactome:R-HSA-6802952|mint:P51114|dip:DIP-40789N interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pUW5/sakWOiRtZpigPhEMOPJBpk9606 rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606 rigid:wale3C23TeFqu4xo5MoaqjVVSZg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P51114 uniprotkb:Q06787 intact:EBI-713291|uniprotkb:A8K9B8|uniprotkb:Q7Z450|uniprotkb:Q8N6R8|ensembl:ENSP00000350170 intact:EBI-366305|ensembl:ENSP00000359506|uniprotkb:Q5PQZ6|uniprotkb:Q16578|uniprotkb:Q99054|uniprotkb:A6NNH4|uniprotkb:D3DWT0|uniprotkb:D3DWT1|uniprotkb:D3DWT2|uniprotkb:G8JL90 psi-mi:fxr1_human(display_long)|uniprotkb:FXR1(gene name)|psi-mi:FXR1(display_short) psi-mi:fmr1_human(display_long)|uniprotkb:FMR1(gene name)|psi-mi:FMR1(display_short)|uniprotkb:Fragile X mental retardation protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478796|imex:IM-26985-471 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001013456.1|refseq:NP_001013457.1|refseq:NP_005078.2|go:"GO:0007517"(muscle organ development)|ensembl:ENSG00000114416(gene)|ensembl:ENST00000357559(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0060538"(skeletal muscle organ development)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR032177|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|go:"GO:0014069"(postsynaptic density)|rcsb pdb:2CPQ|rcsb pdb:3KUF|rcsb pdb:3O8V|reactome:R-HSA-6802952|mint:P51114|dip:DIP-40789N ensembl:ENSG00000102081(gene)|ensembl:ENST00000370475(transcript)|refseq:NP_001172004.1|refseq:NP_001172005.1|refseq:NP_001172010.1|refseq:NP_001172011.1|refseq:NP_002015.1|go:"GO:0043204"(perikaryon)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0034046"("poly(G) binding")|go:"GO:0034644"(cellular response to UV)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043679"(axon terminus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051028"(mRNA transport)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060964"(regulation of gene silencing by miRNA)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070840"(dynein complex binding)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0097386"(glial cell projection)|go:"GO:0098586"(cellular response to virus)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1900453"(negative regulation of long-term synaptic depression)|go:"GO:1901254"(positive regulation of intracellular transport of viral material)|go:"GO:1901386"(negative regulation of voltage-gated calcium channel activity)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1902373"(negative regulation of mRNA catabolic process)|go:"GO:1902416"(positive regulation of mRNA binding)|go:"GO:1902737"(dendritic filopodium)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990812"(growth cone filopodium)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000301"(negative regulation of synaptic vesicle exocytosis)|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:Q06787|rcsb pdb:2BKD|rcsb pdb:2FMR|rcsb pdb:2LA5|rcsb pdb:2QND|rcsb pdb:4OVA|rcsb pdb:4QVZ|rcsb pdb:4QW2|rcsb pdb:5DE5|rcsb pdb:5DE8|rcsb pdb:5DEA|rcsb pdb:5UWJ|rcsb pdb:5UWO|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000766"(negative regulation of cytoplasmic translation)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032196|interpro:IPR036612|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008380"(RNA splicing)|go:"GO:0010369"(chromocenter)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030371"(translation repressor activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032433"(filopodium tip)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|dip:DIP-29509N - - comment:"author score: 58" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pUW5/sakWOiRtZpigPhEMOPJBpk9606 rogid:+iN/J/MbxTcRwgDezYseEDwLep49606 rigid:wale3C23TeFqu4xo5MoaqjVVSZg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P51114 uniprotkb:O43399 intact:EBI-713291|uniprotkb:A8K9B8|uniprotkb:Q7Z450|uniprotkb:Q8N6R8|ensembl:ENSP00000350170 intact:EBI-782604|uniprotkb:Q5U0E0|uniprotkb:Q5JWU6|uniprotkb:Q9H3Z6|intact:EBI-1043547|uniprotkb:O43398|uniprotkb:Q5JWU5|uniprotkb:Q5JWU8|uniprotkb:E1P5G7|uniprotkb:B4DPJ6|ensembl:ENSP00000343547 psi-mi:fxr1_human(display_long)|uniprotkb:FXR1(gene name)|psi-mi:FXR1(display_short) psi-mi:tpd54_human(display_long)|uniprotkb:Tumor protein D52-like 2(gene name synonym)|uniprotkb:TPD52L2(gene name)|psi-mi:TPD52L2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478796|imex:IM-26985-471 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001013456.1|refseq:NP_001013457.1|refseq:NP_005078.2|go:"GO:0007517"(muscle organ development)|ensembl:ENSG00000114416(gene)|ensembl:ENST00000357559(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0060538"(skeletal muscle organ development)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR032177|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|go:"GO:0014069"(postsynaptic density)|rcsb pdb:2CPQ|rcsb pdb:3KUF|rcsb pdb:3O8V|reactome:R-HSA-6802952|mint:P51114|dip:DIP-40789N refseq:NP_001230821.1|refseq:NP_003279.2|refseq:NP_955393.1|refseq:NP_955395.1|refseq:NP_955394.1|refseq:NP_955392.1|ensembl:ENSG00000101150(gene)|ensembl:ENST00000346249(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR007327(Tumor protein D52)|interpro:IPR012341(Six-hairpin glycosidase)|mint:O43399 - - comment:"author score: 77" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pUW5/sakWOiRtZpigPhEMOPJBpk9606 rogid:asqRlZnmqIzXCJ5TAHjxKcj046g9606 rigid:wale3C23TeFqu4xo5MoaqjVVSZg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P51116 uniprotkb:Q9GZP4 intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113 intact:EBI-720463|uniprotkb:Q5QPN6|uniprotkb:Q5QPN7|uniprotkb:Q9NRI8|uniprotkb:B2R7J4|ensembl:ENSP00000246151 psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym) psi-mi:pith1_human(display_long)|uniprotkb:PITHD1(gene name)|psi-mi:PITHD1(display_short)|uniprotkb:AD039(orf name)|uniprotkb:HT014(orf name)|uniprotkb:PP603(orf name)|uniprotkb:C1orf128(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478814|imex:IM-26985-541 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z refseq:NP_065095.2|ensembl:ENSG00000057757(gene)|ensembl:ENST00000246151(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007286"(spermatid development)|go:"GO:0007341"(penetration of zona pellucida)|go:"GO:0045654"(positive regulation of megakaryocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0061956"(penetration of cumulus oophorus)|go:"GO:0097598"(sperm cytoplasmic droplet)|interpro:IPR008979(Galactose-binding like)|interpro:IPR010400(Protein of unknown function DUF1000)|interpro:IPR037047|mint:Q9GZP4 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606 rogid:EVyLiGYjnMIe9iyJvpnbGhVx4qU9606 rigid:Ql3UP2kyPQJgNW8wlUryVPFOMbU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P51116 uniprotkb:Q13685 intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113 intact:EBI-727274|uniprotkb:Q8WUJ9|uniprotkb:Q96H92|ensembl:ENSP00000248450 psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym) psi-mi:aamp_human(display_long)|uniprotkb:AAMP(gene name)|psi-mi:AAMP(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478814|imex:IM-26985-541 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z refseq:NP_001078.2|ensembl:ENSG00000127837(gene)|ensembl:ENST00000248450(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008201"(heparin binding)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0014909"(smooth muscle cell migration)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030154"(cell differentiation)|go:"GO:0045171"(intercellular bridge)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:Q13685|reactome:R-HSA-168638|reactome:R-HSA-177929|reactome:R-HSA-194138|reactome:R-HSA-428930 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606 rogid:H0UzaZMC4fjo4QAXNdfy0BIWmw09606 rigid:Ql3UP2kyPQJgNW8wlUryVPFOMbU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P51116 uniprotkb:Q9NP64 intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113 intact:EBI-746345|uniprotkb:Q6PKH4|uniprotkb:Q9NYG4|uniprotkb:Q9P0M8|uniprotkb:D3DPN4|ensembl:ENSP00000343557|ensembl:ENSP00000362819|uniprotkb:B4DY38 psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym) psi-mi:no40_human(display_long)|uniprotkb:Zinc finger CCHC domain-containing protein 17(gene name synonym)|uniprotkb:Putative S1 RNA-binding domain protein(gene name synonym)|uniprotkb:Pnn-interacting nucleolar protein(gene name synonym)|uniprotkb:ZCCHC17(gene name)|psi-mi:ZCCHC17(display_short)|uniprotkb:HSPC243(orf name)|uniprotkb:HSPC251(orf name)|uniprotkb:LDC4(orf name)|uniprotkb:PS1D(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478814|imex:IM-26985-541 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z refseq:NP_001269495.1|refseq:NP_001269496.1|refseq:NP_001269497.1|refseq:NP_001269498.1|refseq:NP_001269499.1|refseq:NP_001269500.1|refseq:NP_001269501.1|refseq:NP_001269502.1|refseq:NP_001269503.1|refseq:XP_006710744.1|refseq:NP_057589.2|refseq:XP_011539869.1|ensembl:ENSG00000121766(gene)|ensembl:ENST00000344147(transcript)|ensembl:ENST00000373714(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0042802"(identical protein binding)|go:"GO:0043489"(RNA stabilization)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR003029(S1, RNA binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR037320|mint:Q9NP64|rcsb pdb:2CQO - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606 rogid:e71wAulRWX6cM59s3g8R42PWXeU9606 rigid:Ql3UP2kyPQJgNW8wlUryVPFOMbU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P51116 uniprotkb:P63220 intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113 intact:EBI-714051|uniprotkb:P35265|ensembl:ENSP00000345957 psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym) psi-mi:rs21_human(display_long)|uniprotkb:RPS21(gene name)|psi-mi:RPS21(display_short)|uniprotkb:Small ribosomal subunit protein eS21(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478814|imex:IM-26985-541 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z ensembl:ENSG00000171858(gene)|ensembl:ENST00000343986(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000461"("endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|refseq:NP_001015.1|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR001931(Ribosomal protein S21e)|interpro:IPR018279|interpro:IPR038579|mint:P63220|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6ZMO|rcsb pdb:6G5H|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6G5I|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:7K5I|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606 rogid:3gi91+fAL7ogzcoJlVEaN4D+87A9606 rigid:Ql3UP2kyPQJgNW8wlUryVPFOMbU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P51116 uniprotkb:Q06787 intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113 intact:EBI-366305|ensembl:ENSP00000359506|uniprotkb:Q5PQZ6|uniprotkb:Q16578|uniprotkb:Q99054|uniprotkb:A6NNH4|uniprotkb:D3DWT0|uniprotkb:D3DWT1|uniprotkb:D3DWT2|uniprotkb:G8JL90 psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym) psi-mi:fmr1_human(display_long)|uniprotkb:FMR1(gene name)|psi-mi:FMR1(display_short)|uniprotkb:Fragile X mental retardation protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478814|imex:IM-26985-541 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z ensembl:ENSG00000102081(gene)|ensembl:ENST00000370475(transcript)|refseq:NP_001172004.1|refseq:NP_001172005.1|refseq:NP_001172010.1|refseq:NP_001172011.1|refseq:NP_002015.1|go:"GO:0043204"(perikaryon)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0034046"("poly(G) binding")|go:"GO:0034644"(cellular response to UV)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043679"(axon terminus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051028"(mRNA transport)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060964"(regulation of gene silencing by miRNA)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070840"(dynein complex binding)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0097386"(glial cell projection)|go:"GO:0098586"(cellular response to virus)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1900453"(negative regulation of long-term synaptic depression)|go:"GO:1901254"(positive regulation of intracellular transport of viral material)|go:"GO:1901386"(negative regulation of voltage-gated calcium channel activity)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1902373"(negative regulation of mRNA catabolic process)|go:"GO:1902416"(positive regulation of mRNA binding)|go:"GO:1902737"(dendritic filopodium)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990812"(growth cone filopodium)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000301"(negative regulation of synaptic vesicle exocytosis)|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:Q06787|rcsb pdb:2BKD|rcsb pdb:2FMR|rcsb pdb:2LA5|rcsb pdb:2QND|rcsb pdb:4OVA|rcsb pdb:4QVZ|rcsb pdb:4QW2|rcsb pdb:5DE5|rcsb pdb:5DE8|rcsb pdb:5DEA|rcsb pdb:5UWJ|rcsb pdb:5UWO|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000766"(negative regulation of cytoplasmic translation)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032196|interpro:IPR036612|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008380"(RNA splicing)|go:"GO:0010369"(chromocenter)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030371"(translation repressor activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032433"(filopodium tip)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|dip:DIP-29509N - - comment:"author score: 41" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606 rogid:+iN/J/MbxTcRwgDezYseEDwLep49606 rigid:Ql3UP2kyPQJgNW8wlUryVPFOMbU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13283 uniprotkb:Q8WWM7 intact:EBI-1047359|intact:EBI-1384154|ensembl:ENSP00000348578|ensembl:ENSP00000377681|ensembl:ENSP00000430480|ensembl:ENSP00000502880|ensembl:ENSP00000503039|ensembl:ENSP00000503699|ensembl:ENSP00000503939|ensembl:ENSP00000504140|ensembl:ENSP00000504627|uniprotkb:Q5HYE9 intact:EBI-948363|ensembl:ENSP00000338718|uniprotkb:O95135|uniprotkb:Q6NVJ8|uniprotkb:Q6PJW6|uniprotkb:Q8IU61|uniprotkb:Q8IU95|uniprotkb:Q8WWM3|uniprotkb:Q8WWM4|uniprotkb:Q8WWM5|uniprotkb:Q8WWM6|uniprotkb:Q99703|uniprotkb:B9EGM2|uniprotkb:E9PAR9|uniprotkb:A8K1R6|uniprotkb:Q63ZY4 psi-mi:g3bp1_human(display_long)|uniprotkb:G3BP1(gene name)|psi-mi:G3BP1(display_short)|uniprotkb:G3BP(gene name synonym)|uniprotkb:ATP-dependent DNA helicase VIII(gene name synonym)|uniprotkb:GAP SH3 domain-binding protein 1(gene name synonym) psi-mi:atx2l_human(display_long)|uniprotkb:Ataxin-2 domain protein(gene name synonym)|uniprotkb:Ataxin-2-related protein(gene name synonym)|uniprotkb:ATXN2L(gene name)|psi-mi:ATXN2L(display_short)|uniprotkb:A2D(gene name synonym)|uniprotkb:A2LG(gene name synonym)|uniprotkb:A2LP(gene name synonym)|uniprotkb:A2RP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478856|imex:IM-26985-543 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005745.1|refseq:NP_938405.1|ensembl:ENSG00000145907(gene)|go:"GO:0003729"(mRNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0033677"(DNA/RNA helicase activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043204"(perikaryon)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0062029"(positive regulation of stress granule assembly)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018222|interpro:IPR032710|interpro:IPR034374|interpro:IPR034375|interpro:IPR035979|interpro:IPR039539|mint:Q13283|ensembl:ENST00000356245(transcript)|rcsb pdb:3Q90|rcsb pdb:4FCJ|rcsb pdb:4FCM|rcsb pdb:4IIA|rcsb pdb:5FW5|rcsb pdb:6TA7|ensembl:ENST00000394123(transcript)|ensembl:ENST00000522761(transcript)|ensembl:ENST00000676827(transcript)|ensembl:ENST00000676978(transcript)|ensembl:ENST00000677323(transcript)|ensembl:ENST00000678070(transcript)|ensembl:ENST00000678101(transcript)|ensembl:ENST00000678925(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|refseq:XP_006714812.1|refseq:XP_006714813.1|refseq:XP_016864411.1|refseq:XP_016864412.1 ensembl:ENSG00000168488(gene)|ensembl:ENST00000336783(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045296"(cadherin binding)|interpro:IPR009604(Ataxin-2, N-terminal)|interpro:IPR009818(Ataxin-2, C-terminal)|interpro:IPR025852|mint:Q8WWM7|refseq:NP_009176.2|refseq:NP_663760.1|refseq:NP_680780.1|refseq:NP_680781.1|refseq:XP_005255123.1|refseq:NP_059867.3|refseq:NP_680782.1 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:0ZRCHNVEmmtGEOASNwg3kIm2uys9606 rogid:t7lrS10IM/5pt+rrbqBRowZ6b+09606 rigid:Qt6eVN9ylJSD+LhoVQ26xB2lO8s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13283 uniprotkb:Q5T1J5 intact:EBI-1047359|intact:EBI-1384154|ensembl:ENSP00000348578|ensembl:ENSP00000377681|ensembl:ENSP00000430480|ensembl:ENSP00000502880|ensembl:ENSP00000503039|ensembl:ENSP00000503699|ensembl:ENSP00000503939|ensembl:ENSP00000504140|ensembl:ENSP00000504627|uniprotkb:Q5HYE9 intact:EBI-5325274 psi-mi:g3bp1_human(display_long)|uniprotkb:G3BP1(gene name)|psi-mi:G3BP1(display_short)|uniprotkb:G3BP(gene name synonym)|uniprotkb:ATP-dependent DNA helicase VIII(gene name synonym)|uniprotkb:GAP SH3 domain-binding protein 1(gene name synonym) psi-mi:chch9_human(display_long)|uniprotkb:CHCHD2P9(gene name)|psi-mi:CHCHD2P9(display_short)|uniprotkb:C9orf49(gene name synonym)|uniprotkb:CHCHD9(gene name synonym)|uniprotkb:Coiled-coil-helix-coiled-coil-helix domain-containing 2 pseudogene 9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478856|imex:IM-26985-543 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005745.1|refseq:NP_938405.1|ensembl:ENSG00000145907(gene)|go:"GO:0003729"(mRNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0033677"(DNA/RNA helicase activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043204"(perikaryon)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0062029"(positive regulation of stress granule assembly)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018222|interpro:IPR032710|interpro:IPR034374|interpro:IPR034375|interpro:IPR035979|interpro:IPR039539|mint:Q13283|ensembl:ENST00000356245(transcript)|rcsb pdb:3Q90|rcsb pdb:4FCJ|rcsb pdb:4FCM|rcsb pdb:4IIA|rcsb pdb:5FW5|rcsb pdb:6TA7|ensembl:ENST00000394123(transcript)|ensembl:ENST00000522761(transcript)|ensembl:ENST00000676827(transcript)|ensembl:ENST00000676978(transcript)|ensembl:ENST00000677323(transcript)|ensembl:ENST00000678070(transcript)|ensembl:ENST00000678101(transcript)|ensembl:ENST00000678925(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|refseq:XP_006714812.1|refseq:XP_006714813.1|refseq:XP_016864411.1|refseq:XP_016864412.1 go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|mint:Q5T1J5 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:0ZRCHNVEmmtGEOASNwg3kIm2uys9606 rogid:nxLtnxxMIGeGK2oC3BIhcwkacSs9606 rigid:Qt6eVN9ylJSD+LhoVQ26xB2lO8s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13283 uniprotkb:Q99567 intact:EBI-1047359|intact:EBI-1384154|ensembl:ENSP00000348578|ensembl:ENSP00000377681|ensembl:ENSP00000430480|ensembl:ENSP00000502880|ensembl:ENSP00000503039|ensembl:ENSP00000503699|ensembl:ENSP00000503939|ensembl:ENSP00000504140|ensembl:ENSP00000504627|uniprotkb:Q5HYE9 intact:EBI-726178|uniprotkb:Q9BWE5|uniprotkb:D3DTM2|intact:EBI-28967918|ensembl:ENSP00000458954 psi-mi:g3bp1_human(display_long)|uniprotkb:G3BP1(gene name)|psi-mi:G3BP1(display_short)|uniprotkb:G3BP(gene name synonym)|uniprotkb:ATP-dependent DNA helicase VIII(gene name synonym)|uniprotkb:GAP SH3 domain-binding protein 1(gene name synonym) psi-mi:nup88_human(display_long)|uniprotkb:Nucleoporin Nup88(gene name synonym)|uniprotkb:88 kDa nucleoporin(gene name synonym)|uniprotkb:NUP88(gene name)|psi-mi:NUP88(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478856|imex:IM-26985-543 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005745.1|refseq:NP_938405.1|ensembl:ENSG00000145907(gene)|go:"GO:0003729"(mRNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0033677"(DNA/RNA helicase activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043204"(perikaryon)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0062029"(positive regulation of stress granule assembly)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018222|interpro:IPR032710|interpro:IPR034374|interpro:IPR034375|interpro:IPR035979|interpro:IPR039539|mint:Q13283|ensembl:ENST00000356245(transcript)|rcsb pdb:3Q90|rcsb pdb:4FCJ|rcsb pdb:4FCM|rcsb pdb:4IIA|rcsb pdb:5FW5|rcsb pdb:6TA7|ensembl:ENST00000394123(transcript)|ensembl:ENST00000522761(transcript)|ensembl:ENST00000676827(transcript)|ensembl:ENST00000676978(transcript)|ensembl:ENST00000677323(transcript)|ensembl:ENST00000678070(transcript)|ensembl:ENST00000678101(transcript)|ensembl:ENST00000678925(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|refseq:XP_006714812.1|refseq:XP_006714813.1|refseq:XP_016864411.1|refseq:XP_016864412.1 ensembl:ENSP00000458954|refseq:NP_002523.2|refseq:NP_001307582.1|ensembl:ENSG00000108559(gene)|ensembl:ENST00000573584(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005215"(transporter activity)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0017056"(structural constituent of nuclear pore)|interpro:IPR019321|interpro:IPR037700|mint:Q99567|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:0ZRCHNVEmmtGEOASNwg3kIm2uys9606 rogid:4e7YTurNWkXUn9zj0JiD2muc94A9606 rigid:Qt6eVN9ylJSD+LhoVQ26xB2lO8s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13283 uniprotkb:Q7L2J0 intact:EBI-1047359|intact:EBI-1384154|ensembl:ENSP00000348578|ensembl:ENSP00000377681|ensembl:ENSP00000430480|ensembl:ENSP00000502880|ensembl:ENSP00000503039|ensembl:ENSP00000503699|ensembl:ENSP00000503939|ensembl:ENSP00000504140|ensembl:ENSP00000504627|uniprotkb:Q5HYE9 intact:EBI-2371983|uniprotkb:Q9NPD4|uniprotkb:B3KP86|uniprotkb:D6W5V7|ensembl:ENSP00000308546 psi-mi:g3bp1_human(display_long)|uniprotkb:G3BP1(gene name)|psi-mi:G3BP1(display_short)|uniprotkb:G3BP(gene name synonym)|uniprotkb:ATP-dependent DNA helicase VIII(gene name synonym)|uniprotkb:GAP SH3 domain-binding protein 1(gene name synonym) psi-mi:mepce_human(display_long)|uniprotkb:MEPCE(gene name)|psi-mi:MEPCE(display_short)|uniprotkb:BCDIN3(gene name synonym)|uniprotkb:Bicoid-interacting protein 3 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478856|imex:IM-26985-543 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005745.1|refseq:NP_938405.1|ensembl:ENSG00000145907(gene)|go:"GO:0003729"(mRNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0033677"(DNA/RNA helicase activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043204"(perikaryon)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0062029"(positive regulation of stress granule assembly)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018222|interpro:IPR032710|interpro:IPR034374|interpro:IPR034375|interpro:IPR035979|interpro:IPR039539|mint:Q13283|ensembl:ENST00000356245(transcript)|rcsb pdb:3Q90|rcsb pdb:4FCJ|rcsb pdb:4FCM|rcsb pdb:4IIA|rcsb pdb:5FW5|rcsb pdb:6TA7|ensembl:ENST00000394123(transcript)|ensembl:ENST00000522761(transcript)|ensembl:ENST00000676827(transcript)|ensembl:ENST00000676978(transcript)|ensembl:ENST00000677323(transcript)|ensembl:ENST00000678070(transcript)|ensembl:ENST00000678101(transcript)|ensembl:ENST00000678925(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|refseq:XP_006714812.1|refseq:XP_006714813.1|refseq:XP_016864411.1|refseq:XP_016864412.1 refseq:XP_011514712.1|refseq:NP_001181919.1|refseq:NP_001181920.1|refseq:NP_001181921.1|refseq:NP_062552.2|ensembl:ENSG00000146834(gene)|ensembl:ENST00000310512(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001510"(RNA methylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0008171"(O-methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0016073"(snRNA metabolic process)|go:"GO:0017069"(snRNA binding)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0040031"(snRNA modification)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1905382"(positive regulation of snRNA transcription by RNA polymerase II)|go:"GO:1990276"(RNA 5'-methyltransferase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR010675(Bicoid-interacting 3)|interpro:IPR024160|interpro:IPR025714|interpro:IPR029063|interpro:IPR039772|mint:Q7L2J0|rcsb pdb:5UNA|rcsb pdb:6DCB|rcsb pdb:6DCC - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:0ZRCHNVEmmtGEOASNwg3kIm2uys9606 rogid:VGhJoO3FD7nsJPVSBsKuKsPJzEM9606 rigid:Qt6eVN9ylJSD+LhoVQ26xB2lO8s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13283 uniprotkb:C9JQI7 intact:EBI-1047359|intact:EBI-1384154|ensembl:ENSP00000348578|ensembl:ENSP00000377681|ensembl:ENSP00000430480|ensembl:ENSP00000502880|ensembl:ENSP00000503039|ensembl:ENSP00000503699|ensembl:ENSP00000503939|ensembl:ENSP00000504140|ensembl:ENSP00000504627|uniprotkb:Q5HYE9 intact:EBI-20891117|ensembl:ENSP00000401477|uniprotkb:B4DKF4 psi-mi:g3bp1_human(display_long)|uniprotkb:G3BP1(gene name)|psi-mi:G3BP1(display_short)|uniprotkb:G3BP(gene name synonym)|uniprotkb:ATP-dependent DNA helicase VIII(gene name synonym)|uniprotkb:GAP SH3 domain-binding protein 1(gene name synonym) psi-mi:tm232_human(display_long)|uniprotkb:TMEM232(gene name)|psi-mi:TMEM232(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478856|imex:IM-26985-543 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005745.1|refseq:NP_938405.1|ensembl:ENSG00000145907(gene)|go:"GO:0003729"(mRNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0033677"(DNA/RNA helicase activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043204"(perikaryon)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0062029"(positive regulation of stress granule assembly)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018222|interpro:IPR032710|interpro:IPR034374|interpro:IPR034375|interpro:IPR035979|interpro:IPR039539|mint:Q13283|ensembl:ENST00000356245(transcript)|rcsb pdb:3Q90|rcsb pdb:4FCJ|rcsb pdb:4FCM|rcsb pdb:4IIA|rcsb pdb:5FW5|rcsb pdb:6TA7|ensembl:ENST00000394123(transcript)|ensembl:ENST00000522761(transcript)|ensembl:ENST00000676827(transcript)|ensembl:ENST00000676978(transcript)|ensembl:ENST00000677323(transcript)|ensembl:ENST00000678070(transcript)|ensembl:ENST00000678101(transcript)|ensembl:ENST00000678925(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|refseq:XP_006714812.1|refseq:XP_006714813.1|refseq:XP_016864411.1|refseq:XP_016864412.1 ensembl:ENSG00000186952(gene)|ensembl:ENST00000455884(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR031747|mint:C9JQI7|refseq:NP_001034852.3|refseq:XP_006714733.1|refseq:XP_011541854.1|refseq:XP_011541855.1|refseq:XP_011541866.1|refseq:XP_016865193.1 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:0ZRCHNVEmmtGEOASNwg3kIm2uys9606 rogid:R6sGmu0bgPyWfgUoiQqXH4uzA9Y9606 rigid:Qt6eVN9ylJSD+LhoVQ26xB2lO8s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13283 uniprotkb:Q7Z417 intact:EBI-1047359|intact:EBI-1384154|ensembl:ENSP00000348578|ensembl:ENSP00000377681|ensembl:ENSP00000430480|ensembl:ENSP00000502880|ensembl:ENSP00000503039|ensembl:ENSP00000503699|ensembl:ENSP00000503939|ensembl:ENSP00000504140|ensembl:ENSP00000504627|uniprotkb:Q5HYE9 intact:EBI-1210753|intact:EBI-10172018|uniprotkb:A1L3A7|uniprotkb:Q9P2M5|uniprotkb:A1L3A6|ensembl:ENSP00000225388 psi-mi:g3bp1_human(display_long)|uniprotkb:G3BP1(gene name)|psi-mi:G3BP1(display_short)|uniprotkb:G3BP(gene name synonym)|uniprotkb:ATP-dependent DNA helicase VIII(gene name synonym)|uniprotkb:GAP SH3 domain-binding protein 1(gene name synonym) psi-mi:nufp2_human(display_long)|uniprotkb:NUFIP2(gene name)|psi-mi:NUFIP2(display_short)|uniprotkb:KIAA1321(gene name synonym)|uniprotkb:PIG1(orf name)|uniprotkb:FMRP-interacting protein 2(gene name synonym)|uniprotkb:82 kDa FMRP-interacting protein(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 1 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478856|imex:IM-26985-543 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005745.1|refseq:NP_938405.1|ensembl:ENSG00000145907(gene)|go:"GO:0003729"(mRNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0033677"(DNA/RNA helicase activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043204"(perikaryon)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0062029"(positive regulation of stress granule assembly)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018222|interpro:IPR032710|interpro:IPR034374|interpro:IPR034375|interpro:IPR035979|interpro:IPR039539|mint:Q13283|ensembl:ENST00000356245(transcript)|rcsb pdb:3Q90|rcsb pdb:4FCJ|rcsb pdb:4FCM|rcsb pdb:4IIA|rcsb pdb:5FW5|rcsb pdb:6TA7|ensembl:ENST00000394123(transcript)|ensembl:ENST00000522761(transcript)|ensembl:ENST00000676827(transcript)|ensembl:ENST00000676978(transcript)|ensembl:ENST00000677323(transcript)|ensembl:ENST00000678070(transcript)|ensembl:ENST00000678101(transcript)|ensembl:ENST00000678925(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|refseq:XP_006714812.1|refseq:XP_006714813.1|refseq:XP_016864411.1|refseq:XP_016864412.1 refseq:NP_065823.1|dip:DIP-29023N|ensembl:ENSG00000108256(gene)|ensembl:ENST00000225388(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR032747|mint:Q7Z417 - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:0ZRCHNVEmmtGEOASNwg3kIm2uys9606 rogid:zdbkRisveP+8g70umfbEPHTnAgk9606 rigid:Qt6eVN9ylJSD+LhoVQ26xB2lO8s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13283 uniprotkb:Q8IXQ8 intact:EBI-1047359|intact:EBI-1384154|ensembl:ENSP00000348578|ensembl:ENSP00000377681|ensembl:ENSP00000430480|ensembl:ENSP00000502880|ensembl:ENSP00000503039|ensembl:ENSP00000503699|ensembl:ENSP00000503939|ensembl:ENSP00000504140|ensembl:ENSP00000504627|uniprotkb:Q5HYE9 intact:EBI-25478835|ensembl:ENSP00000400514|ensembl:ENSP00000491386|ensembl:ENSP00000492626|uniprotkb:F5GWW8 psi-mi:g3bp1_human(display_long)|uniprotkb:G3BP1(gene name)|psi-mi:G3BP1(display_short)|uniprotkb:G3BP(gene name synonym)|uniprotkb:ATP-dependent DNA helicase VIII(gene name synonym)|uniprotkb:GAP SH3 domain-binding protein 1(gene name synonym) psi-mi:pdzd9_human(display_long)|uniprotkb:PDZD9(gene name)|psi-mi:PDZD9(display_short)|uniprotkb:C16orf65(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478856|imex:IM-26985-543 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005745.1|refseq:NP_938405.1|ensembl:ENSG00000145907(gene)|go:"GO:0003729"(mRNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0033677"(DNA/RNA helicase activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043204"(perikaryon)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0062029"(positive regulation of stress granule assembly)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018222|interpro:IPR032710|interpro:IPR034374|interpro:IPR034375|interpro:IPR035979|interpro:IPR039539|mint:Q13283|ensembl:ENST00000356245(transcript)|rcsb pdb:3Q90|rcsb pdb:4FCJ|rcsb pdb:4FCM|rcsb pdb:4IIA|rcsb pdb:5FW5|rcsb pdb:6TA7|ensembl:ENST00000394123(transcript)|ensembl:ENST00000522761(transcript)|ensembl:ENST00000676827(transcript)|ensembl:ENST00000676978(transcript)|ensembl:ENST00000677323(transcript)|ensembl:ENST00000678070(transcript)|ensembl:ENST00000678101(transcript)|ensembl:ENST00000678925(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|refseq:XP_006714812.1|refseq:XP_006714813.1|refseq:XP_016864411.1|refseq:XP_016864412.1 ensembl:ENSG00000155714(gene)|ensembl:ENSG00000284316(gene)|ensembl:ENST00000424898(transcript)|ensembl:ENST00000639637(transcript)|ensembl:ENST00000639732(transcript)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|interpro:IPR039179|mint:Q8IXQ8|refseq:NP_776167.2|refseq:XP_006721092.1 - - comment:"author score: 28" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:0ZRCHNVEmmtGEOASNwg3kIm2uys9606 rogid:95fj/AEIqYlc5vPRNbZJlVMqtjw9606 rigid:Qt6eVN9ylJSD+LhoVQ26xB2lO8s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13283 uniprotkb:Q14444 intact:EBI-1047359|intact:EBI-1384154|ensembl:ENSP00000348578|ensembl:ENSP00000377681|ensembl:ENSP00000430480|ensembl:ENSP00000502880|ensembl:ENSP00000503039|ensembl:ENSP00000503699|ensembl:ENSP00000503939|ensembl:ENSP00000504140|ensembl:ENSP00000504627|uniprotkb:Q5HYE9 intact:EBI-1047080|uniprotkb:Q15074|intact:EBI-1171814|uniprotkb:Q6IMN4|uniprotkb:A6NMY7|uniprotkb:Q6IMN7|uniprotkb:Q9BV09|intact:EBI-2562858|intact:EBI-3449178|uniprotkb:D3DR06|ensembl:ENSP00000340329|ensembl:ENSP00000434150 psi-mi:g3bp1_human(display_long)|uniprotkb:G3BP1(gene name)|psi-mi:G3BP1(display_short)|uniprotkb:G3BP(gene name synonym)|uniprotkb:ATP-dependent DNA helicase VIII(gene name synonym)|uniprotkb:GAP SH3 domain-binding protein 1(gene name synonym) psi-mi:capr1_human(display_long)|uniprotkb:CAPRIN1(gene name)|psi-mi:CAPRIN1(display_short)|uniprotkb:GPIAP1(gene name synonym)|uniprotkb:GPIP137(gene name synonym)|uniprotkb:M11S1(gene name synonym)|uniprotkb:Cytoplasmic activation- and proliferation-associated protein 1(gene name synonym)|uniprotkb:GPI-anchored membrane protein 1(gene name synonym)|uniprotkb:GPI-anchored protein p137(gene name synonym)|uniprotkb:Cell cycle-associated protein 1(gene name synonym)|uniprotkb:Membrane component chromosome 11 surface marker 1(gene name synonym)|uniprotkb:RNG105(gene name synonym)|uniprotkb:RNA granule protein 105(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478856|imex:IM-26985-543 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005745.1|refseq:NP_938405.1|ensembl:ENSG00000145907(gene)|go:"GO:0003729"(mRNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0033677"(DNA/RNA helicase activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043204"(perikaryon)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0062029"(positive regulation of stress granule assembly)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018222|interpro:IPR032710|interpro:IPR034374|interpro:IPR034375|interpro:IPR035979|interpro:IPR039539|mint:Q13283|ensembl:ENST00000356245(transcript)|rcsb pdb:3Q90|rcsb pdb:4FCJ|rcsb pdb:4FCM|rcsb pdb:4IIA|rcsb pdb:5FW5|rcsb pdb:6TA7|ensembl:ENST00000394123(transcript)|ensembl:ENST00000522761(transcript)|ensembl:ENST00000676827(transcript)|ensembl:ENST00000676978(transcript)|ensembl:ENST00000677323(transcript)|ensembl:ENST00000678070(transcript)|ensembl:ENST00000678101(transcript)|ensembl:ENST00000678925(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|refseq:XP_006714812.1|refseq:XP_006714813.1|refseq:XP_016864411.1|refseq:XP_016864412.1 refseq:NP_005889.3|refseq:NP_976240.1|ensembl:ENSG00000135387(gene)|ensembl:ENST00000341394(transcript)|ensembl:ENST00000532820(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0045202"(synapse)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|interpro:IPR022070|interpro:IPR028816|interpro:IPR041637|mint:Q14444|rcsb pdb:4WBE|rcsb pdb:4WBP|rcsb pdb:6TA7|refseq:XP_016873238.1 - - comment:"author score: 98" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:0ZRCHNVEmmtGEOASNwg3kIm2uys9606 rogid:3c6ZdBClP/D6jIi8NfzBkMc61pI9606 rigid:Qt6eVN9ylJSD+LhoVQ26xB2lO8s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13283 uniprotkb:Q14694 intact:EBI-1047359|intact:EBI-1384154|ensembl:ENSP00000348578|ensembl:ENSP00000377681|ensembl:ENSP00000430480|ensembl:ENSP00000502880|ensembl:ENSP00000503039|ensembl:ENSP00000503699|ensembl:ENSP00000503939|ensembl:ENSP00000504140|ensembl:ENSP00000504627|uniprotkb:Q5HYE9 intact:EBI-2510389|uniprotkb:B4DS84|uniprotkb:B2RDJ8|uniprotkb:Q9BWG7|uniprotkb:Q9NSL7|ensembl:ENSP00000219473 psi-mi:g3bp1_human(display_long)|uniprotkb:G3BP1(gene name)|psi-mi:G3BP1(display_short)|uniprotkb:G3BP(gene name synonym)|uniprotkb:ATP-dependent DNA helicase VIII(gene name synonym)|uniprotkb:GAP SH3 domain-binding protein 1(gene name synonym) psi-mi:ubp10_human(display_long)|uniprotkb:USP10(gene name)|psi-mi:USP10(display_short)|uniprotkb:KIAA0190(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 10(gene name synonym)|uniprotkb:Deubiquitinating enzyme 10(gene name synonym)|uniprotkb:Ubiquitin thioesterase 10(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478856|imex:IM-26985-543 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005745.1|refseq:NP_938405.1|ensembl:ENSG00000145907(gene)|go:"GO:0003729"(mRNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0033677"(DNA/RNA helicase activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043204"(perikaryon)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0062029"(positive regulation of stress granule assembly)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018222|interpro:IPR032710|interpro:IPR034374|interpro:IPR034375|interpro:IPR035979|interpro:IPR039539|mint:Q13283|ensembl:ENST00000356245(transcript)|rcsb pdb:3Q90|rcsb pdb:4FCJ|rcsb pdb:4FCM|rcsb pdb:4IIA|rcsb pdb:5FW5|rcsb pdb:6TA7|ensembl:ENST00000394123(transcript)|ensembl:ENST00000522761(transcript)|ensembl:ENST00000676827(transcript)|ensembl:ENST00000676978(transcript)|ensembl:ENST00000677323(transcript)|ensembl:ENST00000678070(transcript)|ensembl:ENST00000678101(transcript)|ensembl:ENST00000678925(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|refseq:XP_006714812.1|refseq:XP_006714813.1|refseq:XP_016864411.1|refseq:XP_016864412.1 refseq:NP_005144.2|ensembl:ENSP00000219473|ensembl:ENST00000570191|ensembl:ENSP00000457411|refseq:NP_001259004.1|ensembl:ENSG00000103194(gene)|ensembl:ENST00000219473(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019985"(translesion synthesis)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0071347"(cellular response to interleukin-1)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR009818(Ataxin-2, C-terminal)|interpro:IPR018200|interpro:IPR028767|interpro:IPR028889|interpro:IPR038765|mint:Q14694|reactome:R-HSA-5656169|reactome:R-HSA-5689880|go:"GO:0005737"(cytoplasm) - - comment:"author score: 104" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:0ZRCHNVEmmtGEOASNwg3kIm2uys9606 rogid:W34ZdOIilLOVI8SXqCH3rOmmloo9606 rigid:Qt6eVN9ylJSD+LhoVQ26xB2lO8s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13283 uniprotkb:Q9UN86 intact:EBI-1047359|intact:EBI-1384154|ensembl:ENSP00000348578|ensembl:ENSP00000377681|ensembl:ENSP00000430480|ensembl:ENSP00000502880|ensembl:ENSP00000503039|ensembl:ENSP00000503699|ensembl:ENSP00000503939|ensembl:ENSP00000504140|ensembl:ENSP00000504627|uniprotkb:Q5HYE9 intact:EBI-1044298|uniprotkb:O60606|uniprotkb:O75149|uniprotkb:Q9UPA1|ensembl:ENSP00000352738|ensembl:ENSP00000379069|ensembl:ENSP00000503228|ensembl:ENSP00000503239|ensembl:ENSP00000503355|ensembl:ENSP00000503669|ensembl:ENSP00000503911|ensembl:ENSP00000503943|ensembl:ENSP00000504101|ensembl:ENSP00000504159|ensembl:ENSP00000504316|ensembl:ENSP00000504361|ensembl:ENSP00000504371|ensembl:ENSP00000504496|ensembl:ENSP00000504523|ensembl:ENSP00000504585|ensembl:ENSP00000504698|ensembl:ENSP00000503504|uniprotkb:A8K6X1 psi-mi:g3bp1_human(display_long)|uniprotkb:G3BP1(gene name)|psi-mi:G3BP1(display_short)|uniprotkb:G3BP(gene name synonym)|uniprotkb:ATP-dependent DNA helicase VIII(gene name synonym)|uniprotkb:GAP SH3 domain-binding protein 1(gene name synonym) psi-mi:g3bp2_human(display_long)|uniprotkb:GAP SH3 domain-binding protein 2(gene name synonym)|uniprotkb:G3BP2(gene name)|psi-mi:G3BP2(display_short)|uniprotkb:KIAA0660(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478856|imex:IM-26985-543 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005745.1|refseq:NP_938405.1|ensembl:ENSG00000145907(gene)|go:"GO:0003729"(mRNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0033677"(DNA/RNA helicase activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043204"(perikaryon)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0062029"(positive regulation of stress granule assembly)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018222|interpro:IPR032710|interpro:IPR034374|interpro:IPR034375|interpro:IPR035979|interpro:IPR039539|mint:Q13283|ensembl:ENST00000356245(transcript)|rcsb pdb:3Q90|rcsb pdb:4FCJ|rcsb pdb:4FCM|rcsb pdb:4IIA|rcsb pdb:5FW5|rcsb pdb:6TA7|ensembl:ENST00000394123(transcript)|ensembl:ENST00000522761(transcript)|ensembl:ENST00000676827(transcript)|ensembl:ENST00000676978(transcript)|ensembl:ENST00000677323(transcript)|ensembl:ENST00000678070(transcript)|ensembl:ENST00000678101(transcript)|ensembl:ENST00000678925(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|refseq:XP_006714812.1|refseq:XP_006714813.1|refseq:XP_016864411.1|refseq:XP_016864412.1 refseq:NP_036429.2|refseq:NP_987100.1|refseq:NP_987101.1|ensembl:ENSG00000138757(gene)|ensembl:ENST00000677620(transcript)|ensembl:ENST00000678062(transcript)|ensembl:ENST00000678100(transcript)|ensembl:ENST00000678123(transcript)|ensembl:ENST00000678265(transcript)|ensembl:ENST00000678578(transcript)|ensembl:ENST00000678798(transcript)|ensembl:ENST00000678971(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045087"(innate immune response)|go:"GO:0051028"(mRNA transport)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0062029"(positive regulation of stress granule assembly)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018222|interpro:IPR032710|interpro:IPR034376|interpro:IPR034377|interpro:IPR035979|interpro:IPR039539|mint:Q9UN86|rcsb pdb:5DRV|ensembl:ENST00000359707(transcript)|ensembl:ENST00000395719(transcript)|ensembl:ENST00000676584(transcript)|ensembl:ENST00000676974(transcript)|ensembl:ENST00000677162(transcript)|ensembl:ENST00000677171(transcript)|ensembl:ENST00000677201(transcript)|ensembl:ENST00000677333(transcript)|ensembl:ENST00000677566(transcript)|ensembl:ENST00000677606(transcript)|refseq:XP_011530743.1|refseq:XP_005263439.1|refseq:XP_005263440.1|refseq:XP_016864365.1|refseq:XP_016864366.1|refseq:XP_016864367.1|refseq:XP_016864368.1|dip:DIP-50299N - - comment:"author score: 134" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:0ZRCHNVEmmtGEOASNwg3kIm2uys9606 rogid:bYP8U2wviIqJBWcnLQnuoV0MhV89606 rigid:Qt6eVN9ylJSD+LhoVQ26xB2lO8s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35269 uniprotkb:Q9UBQ7 intact:EBI-457886|uniprotkb:Q9BWN0|ensembl:ENSP00000377969|uniprotkb:B2RCS0 intact:EBI-372445|uniprotkb:Q9H3E9|uniprotkb:Q9UKX1|ensembl:ENSP00000313432|uniprotkb:Q5T945|uniprotkb:Q9H636 psi-mi:t2fa_human(display_long)|uniprotkb:Transcription initiation factor IIF subunit alpha(gene name synonym)|uniprotkb:GTF2F1(gene name)|psi-mi:GTF2F1(display_short)|uniprotkb:RAP74(gene name synonym)|uniprotkb:Transcription initiation factor RAP74(gene name synonym)|uniprotkb:General transcription factor IIF 74 kDa subunit(gene name synonym) psi-mi:grhpr_human(display_long)|uniprotkb:MSTP035(orf name)|uniprotkb:GRHPR(gene name)|psi-mi:GRHPR(display_short)|uniprotkb:GLXR(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478892|imex:IM-26985-165 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR008851(Transcription initiation factor IIF, alpha subunit)|interpro:IPR011039(Transcription Factor IIF, Rap30/Rap74, interaction)|interpro:IPR036388|interpro:IPR036390|mint:P35269|rcsb pdb:1F3U|rcsb pdb:1I27|rcsb pdb:1J2X|rcsb pdb:1NHA|rcsb pdb:1ONV|rcsb pdb:2K7L|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009615"(response to virus)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|rcsb pdb:6O9L|refseq:NP_002087.2|go:"GO:0001096"(TFIIF-class transcription factor complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005674"(transcription factor TFIIF complex)|go:"GO:0006366"(transcription by RNA polymerase II)|ensembl:ENSG00000125651(gene)|ensembl:ENST00000394456(transcript)|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVS|rcsb pdb:7NVT|rcsb pdb:7NVU|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|dip:DIP-677N refseq:NP_036335.1|go:"GO:0043648"(dicarboxylic acid metabolic process)|go:"GO:0046487"(glyoxylate metabolic process)|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070402"(NADPH binding)|go:"GO:1902494"(catalytic complex)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029753|interpro:IPR036291|mint:Q9UBQ7|rcsb pdb:2GCG|rcsb pdb:2H1S|rcsb pdb:2Q50|rcsb pdb:2WWR|reactome:R-HSA-389661|ensembl:ENSG00000137106(gene)|ensembl:ENST00000318158(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0007588"(excretion)|go:"GO:0008465"(glycerate dehydrogenase activity)|go:"GO:0016618"(hydroxypyruvate reductase activity)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0030267"("glyoxylate reductase (NADP+) activity")|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0042803"(protein homodimerization activity) - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:UHTMke+O4hI3MIvpMB6opKwV3Go9606 rogid:qPHrh5I5wHI5MWba4zncz26cUnQ9606 rigid:NpS2nhZL2ajHmv/kiDmIR1/QEJc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35269 uniprotkb:P13984 intact:EBI-457886|uniprotkb:Q9BWN0|ensembl:ENSP00000377969|uniprotkb:B2RCS0 intact:EBI-1030560|uniprotkb:A6NNS5|uniprotkb:Q5W0H3|ensembl:ENSP00000340823 psi-mi:t2fa_human(display_long)|uniprotkb:Transcription initiation factor IIF subunit alpha(gene name synonym)|uniprotkb:GTF2F1(gene name)|psi-mi:GTF2F1(display_short)|uniprotkb:RAP74(gene name synonym)|uniprotkb:Transcription initiation factor RAP74(gene name synonym)|uniprotkb:General transcription factor IIF 74 kDa subunit(gene name synonym) psi-mi:t2fb_human(display_long)|uniprotkb:GTF2F2(gene name)|psi-mi:GTF2F2(display_short)|uniprotkb:RAP30(gene name synonym)|uniprotkb:Transcription initiation factor IIF subunit beta(gene name synonym)|uniprotkb:ATP-dependent helicase GTF2F2(gene name synonym)|uniprotkb:Transcription initiation factor RAP30(gene name synonym)|uniprotkb:General transcription factor IIF 30 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478892|imex:IM-26985-165 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR008851(Transcription initiation factor IIF, alpha subunit)|interpro:IPR011039(Transcription Factor IIF, Rap30/Rap74, interaction)|interpro:IPR036388|interpro:IPR036390|mint:P35269|rcsb pdb:1F3U|rcsb pdb:1I27|rcsb pdb:1J2X|rcsb pdb:1NHA|rcsb pdb:1ONV|rcsb pdb:2K7L|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009615"(response to virus)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|rcsb pdb:6O9L|refseq:NP_002087.2|go:"GO:0001096"(TFIIF-class transcription factor complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005674"(transcription factor TFIIF complex)|go:"GO:0006366"(transcription by RNA polymerase II)|ensembl:ENSG00000125651(gene)|ensembl:ENST00000394456(transcript)|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVS|rcsb pdb:7NVT|rcsb pdb:7NVU|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|dip:DIP-677N refseq:NP_004119.1|ensembl:ENSG00000188342(gene)|ensembl:ENST00000340473(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005674"(transcription factor TFIIF complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003196(Transcription initiation factor IIF, beta subunit)|interpro:IPR011039(Transcription Factor IIF, Rap30/Rap74, interaction)|interpro:IPR036388|interpro:IPR040450|interpro:IPR040504|mint:P13984|interpro:IPR036390|rcsb pdb:1BBY|rcsb pdb:1F3U|rcsb pdb:2BBY|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6O9L|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVS|rcsb pdb:7NVT|rcsb pdb:7NVU|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|dip:DIP-41680N - - comment:"author score: 54" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:UHTMke+O4hI3MIvpMB6opKwV3Go9606 rogid:kAfbXXjVR1dmgs+WHBlTuG6AVTs9606 rigid:NpS2nhZL2ajHmv/kiDmIR1/QEJc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16403 uniprotkb:Q13888 intact:EBI-358372|ensembl:ENSP00000339566|uniprotkb:A8K4I2 intact:EBI-1565170|uniprotkb:Q15570|uniprotkb:Q15571|uniprotkb:Q9BS41|ensembl:ENSP00000274400|ensembl:ENSP00000328901|ensembl:ENSP00000477954|ensembl:ENSP00000479262|ensembl:ENSP00000480548|ensembl:ENSP00000486014 psi-mi:h12_human(display_long)|uniprotkb:H1-2(gene name)|psi-mi:H1-2(display_short)|uniprotkb:H1F2(gene name synonym)|uniprotkb:HIST1H1C(gene name synonym)|uniprotkb:Histone H1c(gene name synonym)|uniprotkb:Histone H1d(gene name synonym)|uniprotkb:Histone H1s-1(gene name synonym) psi-mi:tf2h2_human(display_long)|uniprotkb:General transcription factor IIH polypeptide 2(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p44 subunit(gene name synonym)|uniprotkb:Basic transcription factor 2 44 kDa subunit(gene name synonym)|uniprotkb:GTF2H2(gene name)|psi-mi:GTF2H2(display_short)|uniprotkb:BTF2P44(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25478904|imex:IM-26985-545 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005310.1|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P16403|reactome:R-HSA-140342|reactome:R-HSA-2559584|ensembl:ENSG00000187837(gene)|ensembl:ENST00000343677(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|dip:DIP-36359N refseq:NP_001506.1|refseq:XP_016864894.1|refseq:XP_016864895.1|refseq:XP_016864892.1|refseq:XP_016864893.1|dip:DIP-786N|ensembl:ENSG00000145736(gene)|ensembl:ENSG00000275045(gene)|ensembl:ENSG00000276910(gene)|ensembl:ENST00000274400(transcript)|ensembl:ENST00000330280(transcript)|ensembl:ENST00000612581(transcript)|ensembl:ENST00000617228(transcript)|ensembl:ENST00000619997(transcript)|ensembl:ENST00000628423(transcript)|go:"GO:0000438"(core TFIIH complex portion of holo TFIIH complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009411"(response to UV)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:1905776"(positive regulation of DNA helicase activity)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR004595(TFIIH C1-like, C-terminal)|interpro:IPR007198(Ssl1-like)|interpro:IPR012170(TFIIH basal transcription factor complex, subunit SSL1)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036465|mint:Q13888|rcsb pdb:1Z60|rcsb pdb:5IVW|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5O85|rcsb pdb:5OF4|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:6RO4|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075 - comment:"author score: 12" - figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:eRT5bTyBJUg6nRANMRYZekT4N+g9606 rogid:U4tPk4UlGiQz+exwhYG9kg7xGAM9606 rigid:G3TPLe4/PJc71IjbIv4Hzfn2ipU false - tandem tag:n-n - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13889 uniprotkb:Q6P1K8 intact:EBI-6380459|uniprotkb:B4DNZ6|ensembl:ENSP00000445162|uniprotkb:B2R819|uniprotkb:Q7L0G0|uniprotkb:Q96AT7 intact:EBI-8469755|uniprotkb:A6NED9|uniprotkb:A8K8J6|uniprotkb:B2RCU4|uniprotkb:B7ZW39|intact:MINT-4906733|ensembl:ENSP00000370105|ensembl:ENSP00000422907|ensembl:ENSP00000480471|ensembl:ENSP00000483148 psi-mi:tf2h3_human(display_long)|uniprotkb:GTF2H3(gene name)|psi-mi:GTF2H3(display_short)|uniprotkb:Basic transcription factor 2 34 kDa subunit(gene name synonym)|uniprotkb:General transcription factor IIH polypeptide 3(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p34 subunit(gene name synonym) psi-mi:t2h2l_human(display_long)|uniprotkb:GTF2H2C(gene name)|psi-mi:GTF2H2C(display_short)|uniprotkb:GTF2H2C_2(gene name)|psi-mi:GTF2H2C_2(display_short)|uniprotkb:GTF2H2D(gene name synonym)|uniprotkb:General transcription factor IIH polypeptide 2-like protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478913|imex:IM-26985-473 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000111358(gene)|ensembl:ENST00000543341(transcript)|go:"GO:0000438"(core TFIIH complex portion of holo TFIIH complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR004600(Transcription factor Tfb4)|interpro:IPR036465|mint:Q13889|rcsb pdb:5IVW|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5O85|rcsb pdb:5OF4|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:6RO4|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-75955|dip:DIP-787N|refseq:NP_001258795.1|refseq:NP_001258796.1|refseq:NP_001258797.1|refseq:NP_001507.2 refseq:NP_001035955.1|refseq:NP_001092198.1|refseq:XP_005248645.1|refseq:XP_005248647.1|refseq:XP_006714751.1|ensembl:ENSG00000183474(gene)|ensembl:ENSG00000274675(gene)|ensembl:ENST00000380729(transcript)|ensembl:ENST00000510979(transcript)|ensembl:ENST00000619699(transcript)|ensembl:ENST00000621406(transcript)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR004595(TFIIH C1-like, C-terminal)|interpro:IPR007198(Ssl1-like)|interpro:IPR012170(TFIIH basal transcription factor complex, subunit SSL1)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036465|mint:Q6P1K8 - - comment:mint|comment:homomint|comment:"author score: 78" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Ca5tFYnStJdHF1eNPEwLZtKB0+09606 rogid:T36j4FIYLk1oSgzWnshu2uW/UbI9606 rigid:wqT/KDP+JNu9r/U0GuCexKDfa80 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13889 uniprotkb:P31944 intact:EBI-6380459|uniprotkb:B4DNZ6|ensembl:ENSP00000445162|uniprotkb:B2R819|uniprotkb:Q7L0G0|uniprotkb:Q96AT7 intact:EBI-2510738|ensembl:ENSP00000393417|uniprotkb:O95823|uniprotkb:Q3SYC9 psi-mi:tf2h3_human(display_long)|uniprotkb:GTF2H3(gene name)|psi-mi:GTF2H3(display_short)|uniprotkb:Basic transcription factor 2 34 kDa subunit(gene name synonym)|uniprotkb:General transcription factor IIH polypeptide 3(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p34 subunit(gene name synonym) psi-mi:caspe_human(display_long)|uniprotkb:CASP14(gene name)|psi-mi:CASP14(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478913|imex:IM-26985-473 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000111358(gene)|ensembl:ENST00000543341(transcript)|go:"GO:0000438"(core TFIIH complex portion of holo TFIIH complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR004600(Transcription factor Tfb4)|interpro:IPR036465|mint:Q13889|rcsb pdb:5IVW|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5O85|rcsb pdb:5OF4|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:6RO4|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-75955|dip:DIP-787N|refseq:NP_001258795.1|refseq:NP_001258796.1|refseq:NP_001258797.1|refseq:NP_001507.2 interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR029030|interpro:IPR033139|interpro:IPR033174|mint:P31944|reactome:R-HSA-6809371|ensembl:ENSG00000105141(gene)|ensembl:ENST00000427043(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0031424"(keratinization)|go:"GO:0045095"(keratin filament)|go:"GO:0070268"(cornification)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|refseq:NP_036246.1 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Ca5tFYnStJdHF1eNPEwLZtKB0+09606 rogid:e8QPsuebgXeKJEuMm/KU0WAOs3k9606 rigid:wqT/KDP+JNu9r/U0GuCexKDfa80 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13889 uniprotkb:Q5T1J5 intact:EBI-6380459|uniprotkb:B4DNZ6|ensembl:ENSP00000445162|uniprotkb:B2R819|uniprotkb:Q7L0G0|uniprotkb:Q96AT7 intact:EBI-5325274 psi-mi:tf2h3_human(display_long)|uniprotkb:GTF2H3(gene name)|psi-mi:GTF2H3(display_short)|uniprotkb:Basic transcription factor 2 34 kDa subunit(gene name synonym)|uniprotkb:General transcription factor IIH polypeptide 3(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p34 subunit(gene name synonym) psi-mi:chch9_human(display_long)|uniprotkb:CHCHD2P9(gene name)|psi-mi:CHCHD2P9(display_short)|uniprotkb:C9orf49(gene name synonym)|uniprotkb:CHCHD9(gene name synonym)|uniprotkb:Coiled-coil-helix-coiled-coil-helix domain-containing 2 pseudogene 9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478913|imex:IM-26985-473 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000111358(gene)|ensembl:ENST00000543341(transcript)|go:"GO:0000438"(core TFIIH complex portion of holo TFIIH complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR004600(Transcription factor Tfb4)|interpro:IPR036465|mint:Q13889|rcsb pdb:5IVW|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5O85|rcsb pdb:5OF4|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:6RO4|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-75955|dip:DIP-787N|refseq:NP_001258795.1|refseq:NP_001258796.1|refseq:NP_001258797.1|refseq:NP_001507.2 go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|mint:Q5T1J5 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Ca5tFYnStJdHF1eNPEwLZtKB0+09606 rogid:nxLtnxxMIGeGK2oC3BIhcwkacSs9606 rigid:wqT/KDP+JNu9r/U0GuCexKDfa80 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13889 uniprotkb:P63092 intact:EBI-6380459|uniprotkb:B4DNZ6|ensembl:ENSP00000445162|uniprotkb:B2R819|uniprotkb:Q7L0G0|uniprotkb:Q96AT7 intact:EBI-1047114|uniprotkb:P04895|uniprotkb:Q12927|uniprotkb:Q5JWD2|uniprotkb:Q5JWD4|uniprotkb:Q5JWD5|uniprotkb:Q6NR75|uniprotkb:Q6NXS0|uniprotkb:Q8TBC0|uniprotkb:Q96H70|uniprotkb:Q14433|uniprotkb:Q32P26|uniprotkb:E1P5G5|ensembl:ENSP00000360126|uniprotkb:A6NI00|intact:EBI-10977858 psi-mi:tf2h3_human(display_long)|uniprotkb:GTF2H3(gene name)|psi-mi:GTF2H3(display_short)|uniprotkb:Basic transcription factor 2 34 kDa subunit(gene name synonym)|uniprotkb:General transcription factor IIH polypeptide 3(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p34 subunit(gene name synonym) psi-mi:gnas2_human(display_long)|uniprotkb:Adenylate cyclase-stimulating G alpha protein(gene name synonym)|uniprotkb:GNAS(gene name)|psi-mi:GNAS(display_short)|uniprotkb:GNAS1(gene name synonym)|uniprotkb:GSP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478913|imex:IM-26985-473 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000111358(gene)|ensembl:ENST00000543341(transcript)|go:"GO:0000438"(core TFIIH complex portion of holo TFIIH complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR004600(Transcription factor Tfb4)|interpro:IPR036465|mint:Q13889|rcsb pdb:5IVW|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5O85|rcsb pdb:5OF4|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:6RO4|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-75955|dip:DIP-787N|refseq:NP_001258795.1|refseq:NP_001258796.1|refseq:NP_001258797.1|refseq:NP_001507.2 refseq:NP_001070958.1|refseq:NP_001296769.1|refseq:NP_536350.2|refseq:NP_000507.1|refseq:NP_001070956.1|refseq:NP_001070957.1|ensembl:ENSG00000087460(gene)|ensembl:ENST00000371085(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005834"(heterotrimeric G-protein complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0016020"(membrane)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0031683"(G-protein beta/gamma-subunit complex binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043950"(positive regulation of cAMP-mediated signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0046907"(intracellular transport)|go:"GO:0048589"(developmental growth)|go:"GO:0050890"(cognition)|go:"GO:0060348"(bone development)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0071870"(cellular response to catecholamine stimulus)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR000367(G-protein alpha subunit, group S)|interpro:IPR001019("Guanine nucleotide binding protein (G-protein), alpha subunit")|interpro:IPR011025(G protein alpha subunit, helical insertion)|interpro:IPR027417|mint:P63092|rcsb pdb:5G53|rcsb pdb:5UZ7|rcsb pdb:5VAI|rcsb pdb:6AU6|rcsb pdb:6B3J|rcsb pdb:6E3Y|rcsb pdb:6E67|rcsb pdb:6EG8|rcsb pdb:6GDG|rcsb pdb:6LI3|rcsb pdb:6LMK|rcsb pdb:6LPB|rcsb pdb:6M1H|rcsb pdb:6M1I|rcsb pdb:6NI3|rcsb pdb:6NIY|rcsb pdb:6ORV|rcsb pdb:6P9X|rcsb pdb:6P9Y|rcsb pdb:6PB0|rcsb pdb:6PB1|rcsb pdb:6UUN|rcsb pdb:6UUS|rcsb pdb:6UVA|rcsb pdb:6VCB|rcsb pdb:6VN7|rcsb pdb:6WHC|rcsb pdb:6WI9|rcsb pdb:6WPW|rcsb pdb:6WZG|rcsb pdb:6X18|rcsb pdb:6X19|rcsb pdb:6X1A|rcsb pdb:6XOX|rcsb pdb:7BB6|rcsb pdb:7BB7|rcsb pdb:7BPH|rcsb pdb:7BW0|rcsb pdb:7BZ2|rcsb pdb:7C2E|rcsb pdb:7CFM|rcsb pdb:7CFN|rcsb pdb:7CKW|rcsb pdb:7CKX|rcsb pdb:7CKY|rcsb pdb:7CKZ|rcsb pdb:7CRH|rcsb pdb:7CX2|rcsb pdb:7CX3|rcsb pdb:7CX4|rcsb pdb:7CZ5|rcsb pdb:7D3S|rcsb pdb:7D7M|rcsb pdb:7DHI|rcsb pdb:7DHR|rcsb pdb:7JOZ|rcsb pdb:7JV5|rcsb pdb:7JVP|rcsb pdb:7JVQ|rcsb pdb:7KH0|rcsb pdb:7LCI|rcsb pdb:7LJC|rcsb pdb:7LJD|rcsb pdb:7MBX|reactome:R-HSA-163359|reactome:R-HSA-164378|reactome:R-HSA-381676|reactome:R-HSA-392851|reactome:R-HSA-418555|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-420092|reactome:R-HSA-432040|reactome:R-HSA-5610787|reactome:R-HSA-9660821|refseq:NP_536351.1 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Ca5tFYnStJdHF1eNPEwLZtKB0+09606 rogid:fUnrdxwx4bBAqE3iO2cCB3UInyg9606 rigid:wqT/KDP+JNu9r/U0GuCexKDfa80 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13889 uniprotkb:Q6ZYL4 intact:EBI-6380459|uniprotkb:B4DNZ6|ensembl:ENSP00000445162|uniprotkb:B2R819|uniprotkb:Q7L0G0|uniprotkb:Q96AT7 intact:EBI-6380438|ensembl:ENSP00000476100|uniprotkb:Q0P5V8 psi-mi:tf2h3_human(display_long)|uniprotkb:GTF2H3(gene name)|psi-mi:GTF2H3(display_short)|uniprotkb:Basic transcription factor 2 34 kDa subunit(gene name synonym)|uniprotkb:General transcription factor IIH polypeptide 3(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p34 subunit(gene name synonym) psi-mi:tf2h5_human(display_long)|uniprotkb:TFIIH subunit p8(gene name synonym)|uniprotkb:GTF2H5(gene name)|psi-mi:GTF2H5(display_short)|uniprotkb:C6orf175(gene name synonym)|uniprotkb:TTDA(gene name synonym)|uniprotkb:General transcription factor IIH polypeptide 5(gene name synonym)|uniprotkb:TFB5 ortholog(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex TTD-A subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478913|imex:IM-26985-473 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000111358(gene)|ensembl:ENST00000543341(transcript)|go:"GO:0000438"(core TFIIH complex portion of holo TFIIH complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR004600(Transcription factor Tfb4)|interpro:IPR036465|mint:Q13889|rcsb pdb:5IVW|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5O85|rcsb pdb:5OF4|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:6RO4|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-75955|dip:DIP-787N|refseq:NP_001258795.1|refseq:NP_001258796.1|refseq:NP_001258797.1|refseq:NP_001507.2 ensembl:ENSG00000272047(gene)|ensembl:ENST00000607778(transcript)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006294"(nucleotide-excision repair, preincision complex assembly)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071480"(cellular response to gamma radiation)|interpro:IPR009400(Nucleotide excision repair, TFIIH, subunit TTDA)|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|interpro:IPR035935|mint:Q6ZYL4|rcsb pdb:1YDL|rcsb pdb:2JNJ|rcsb pdb:5IVW|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVV|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5OF4|rcsb pdb:7NVZ|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|rcsb pdb:6RO4|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|dip:DIP-29188N|refseq:NP_997001.1 - - comment:"author score: 59" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Ca5tFYnStJdHF1eNPEwLZtKB0+09606 rogid:6qEk3oQgejWFca2xqWRScoFdxNM9606 rigid:wqT/KDP+JNu9r/U0GuCexKDfa80 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13889 uniprotkb:P35269 intact:EBI-6380459|uniprotkb:B4DNZ6|ensembl:ENSP00000445162|uniprotkb:B2R819|uniprotkb:Q7L0G0|uniprotkb:Q96AT7 intact:EBI-457886|uniprotkb:Q9BWN0|ensembl:ENSP00000377969|uniprotkb:B2RCS0 psi-mi:tf2h3_human(display_long)|uniprotkb:GTF2H3(gene name)|psi-mi:GTF2H3(display_short)|uniprotkb:Basic transcription factor 2 34 kDa subunit(gene name synonym)|uniprotkb:General transcription factor IIH polypeptide 3(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p34 subunit(gene name synonym) psi-mi:t2fa_human(display_long)|uniprotkb:Transcription initiation factor IIF subunit alpha(gene name synonym)|uniprotkb:GTF2F1(gene name)|psi-mi:GTF2F1(display_short)|uniprotkb:RAP74(gene name synonym)|uniprotkb:Transcription initiation factor RAP74(gene name synonym)|uniprotkb:General transcription factor IIF 74 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478913|imex:IM-26985-473 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000111358(gene)|ensembl:ENST00000543341(transcript)|go:"GO:0000438"(core TFIIH complex portion of holo TFIIH complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR004600(Transcription factor Tfb4)|interpro:IPR036465|mint:Q13889|rcsb pdb:5IVW|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5O85|rcsb pdb:5OF4|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:6RO4|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-75955|dip:DIP-787N|refseq:NP_001258795.1|refseq:NP_001258796.1|refseq:NP_001258797.1|refseq:NP_001507.2 go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR008851(Transcription initiation factor IIF, alpha subunit)|interpro:IPR011039(Transcription Factor IIF, Rap30/Rap74, interaction)|interpro:IPR036388|interpro:IPR036390|mint:P35269|rcsb pdb:1F3U|rcsb pdb:1I27|rcsb pdb:1J2X|rcsb pdb:1NHA|rcsb pdb:1ONV|rcsb pdb:2K7L|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009615"(response to virus)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|rcsb pdb:6O9L|refseq:NP_002087.2|go:"GO:0001096"(TFIIF-class transcription factor complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005674"(transcription factor TFIIF complex)|go:"GO:0006366"(transcription by RNA polymerase II)|ensembl:ENSG00000125651(gene)|ensembl:ENST00000394456(transcript)|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVS|rcsb pdb:7NVT|rcsb pdb:7NVU|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|dip:DIP-677N - - comment:"author score: 88" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Ca5tFYnStJdHF1eNPEwLZtKB0+09606 rogid:UHTMke+O4hI3MIvpMB6opKwV3Go9606 rigid:wqT/KDP+JNu9r/U0GuCexKDfa80 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13889 uniprotkb:Q92759 intact:EBI-6380459|uniprotkb:B4DNZ6|ensembl:ENSP00000445162|uniprotkb:B2R819|uniprotkb:Q7L0G0|uniprotkb:Q96AT7 intact:EBI-6380495|ensembl:ENSP00000259895|ensembl:ENSP00000365493|ensembl:ENSP00000365504|ensembl:ENSP00000383300|ensembl:ENSP00000387980|ensembl:ENSP00000388227|ensembl:ENSP00000395497|ensembl:ENSP00000396251|ensembl:ENSP00000399554|ensembl:ENSP00000401105|ensembl:ENSP00000403156|ensembl:ENSP00000409483|uniprotkb:Q76KU4|uniprotkb:B4DTJ5 psi-mi:tf2h3_human(display_long)|uniprotkb:GTF2H3(gene name)|psi-mi:GTF2H3(display_short)|uniprotkb:Basic transcription factor 2 34 kDa subunit(gene name synonym)|uniprotkb:General transcription factor IIH polypeptide 3(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p34 subunit(gene name synonym) psi-mi:tf2h4_human(display_long)|uniprotkb:GTF2H4(gene name)|psi-mi:GTF2H4(display_short)|uniprotkb:Basic transcription factor 2 52 kDa subunit(gene name synonym)|uniprotkb:General transcription factor IIH polypeptide 4(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p52 subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478913|imex:IM-26985-473 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000111358(gene)|ensembl:ENST00000543341(transcript)|go:"GO:0000438"(core TFIIH complex portion of holo TFIIH complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR004600(Transcription factor Tfb4)|interpro:IPR036465|mint:Q13889|rcsb pdb:5IVW|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5O85|rcsb pdb:5OF4|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:6RO4|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-75955|dip:DIP-787N|refseq:NP_001258795.1|refseq:NP_001258796.1|refseq:NP_001258797.1|refseq:NP_001507.2 rcsb pdb:5OF4|rcsb pdb:6NMI|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:6RO4|reactome:R-HSA-167158|rcsb pdb:7EGB|reactome:R-HSA-167160|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|reactome:R-HSA-167161|rcsb pdb:7NVR|rcsb pdb:7NVV|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-72086|reactome:R-HSA-73762|rcsb pdb:7NVW|reactome:R-HSA-73772|rcsb pdb:7NVX|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|rcsb pdb:7NVY|reactome:R-HSA-77075|rcsb pdb:7NVZ|ensembl:ENSG00000213780(gene)|ensembl:ENSG00000221974(gene)|ensembl:ENSG00000226384(gene)|ensembl:ENSG00000233149(gene)|ensembl:ENSG00000234370(gene)|ensembl:ENSG00000236895(gene)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|ensembl:ENST00000259895(transcript)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR004598(Transcription factor Tfb2)|interpro:IPR040662|mint:Q92759|rcsb pdb:5IVW|rcsb pdb:5IY6|rcsb pdb:5IY7|ensembl:ENST00000376316(transcript)|ensembl:ENST00000376326(transcript)|rcsb pdb:5IY8|ensembl:ENST00000400450(transcript)|ensembl:ENST00000413314(transcript)|rcsb pdb:5IY9|ensembl:ENST00000416773(transcript)|ensembl:ENST00000423881(transcript)|ensembl:ENST00000434226(transcript)|ensembl:ENST00000435498(transcript)|ensembl:ENST00000438348(transcript)|ensembl:ENST00000440824(transcript)|ensembl:ENST00000456968(transcript)|go:"GO:0000438"(core TFIIH complex portion of holo TFIIH complex)|dip:DIP-48376N|refseq:NP_001508.1 - - comment:"author score: 129" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Ca5tFYnStJdHF1eNPEwLZtKB0+09606 rogid:vQJkQt6yfTyMyQ6oYP1HpNv7hlY9606 rigid:wqT/KDP+JNu9r/U0GuCexKDfa80 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13889 uniprotkb:Q13888 intact:EBI-6380459|uniprotkb:B4DNZ6|ensembl:ENSP00000445162|uniprotkb:B2R819|uniprotkb:Q7L0G0|uniprotkb:Q96AT7 intact:EBI-1565170|uniprotkb:Q15570|uniprotkb:Q15571|uniprotkb:Q9BS41|ensembl:ENSP00000274400|ensembl:ENSP00000328901|ensembl:ENSP00000477954|ensembl:ENSP00000479262|ensembl:ENSP00000480548|ensembl:ENSP00000486014 psi-mi:tf2h3_human(display_long)|uniprotkb:GTF2H3(gene name)|psi-mi:GTF2H3(display_short)|uniprotkb:Basic transcription factor 2 34 kDa subunit(gene name synonym)|uniprotkb:General transcription factor IIH polypeptide 3(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p34 subunit(gene name synonym) psi-mi:tf2h2_human(display_long)|uniprotkb:General transcription factor IIH polypeptide 2(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p44 subunit(gene name synonym)|uniprotkb:Basic transcription factor 2 44 kDa subunit(gene name synonym)|uniprotkb:GTF2H2(gene name)|psi-mi:GTF2H2(display_short)|uniprotkb:BTF2P44(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478913|imex:IM-26985-473 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000111358(gene)|ensembl:ENST00000543341(transcript)|go:"GO:0000438"(core TFIIH complex portion of holo TFIIH complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR004600(Transcription factor Tfb4)|interpro:IPR036465|mint:Q13889|rcsb pdb:5IVW|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5O85|rcsb pdb:5OF4|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:6RO4|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-75955|dip:DIP-787N|refseq:NP_001258795.1|refseq:NP_001258796.1|refseq:NP_001258797.1|refseq:NP_001507.2 refseq:NP_001506.1|refseq:XP_016864894.1|refseq:XP_016864895.1|refseq:XP_016864892.1|refseq:XP_016864893.1|dip:DIP-786N|ensembl:ENSG00000145736(gene)|ensembl:ENSG00000275045(gene)|ensembl:ENSG00000276910(gene)|ensembl:ENST00000274400(transcript)|ensembl:ENST00000330280(transcript)|ensembl:ENST00000612581(transcript)|ensembl:ENST00000617228(transcript)|ensembl:ENST00000619997(transcript)|ensembl:ENST00000628423(transcript)|go:"GO:0000438"(core TFIIH complex portion of holo TFIIH complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0002031"(G protein-coupled receptor internalization)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009411"(response to UV)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:1905776"(positive regulation of DNA helicase activity)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR004595(TFIIH C1-like, C-terminal)|interpro:IPR007198(Ssl1-like)|interpro:IPR012170(TFIIH basal transcription factor complex, subunit SSL1)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036465|mint:Q13888|rcsb pdb:1Z60|rcsb pdb:5IVW|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5O85|rcsb pdb:5OF4|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:6RO4|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075 - - comment:"author score: 130" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Ca5tFYnStJdHF1eNPEwLZtKB0+09606 rogid:U4tPk4UlGiQz+exwhYG9kg7xGAM9606 rigid:wqT/KDP+JNu9r/U0GuCexKDfa80 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13889 uniprotkb:P32780 intact:EBI-6380459|uniprotkb:B4DNZ6|ensembl:ENSP00000445162|uniprotkb:B2R819|uniprotkb:Q7L0G0|uniprotkb:Q96AT7 intact:EBI-715539|uniprotkb:Q9H5K5|uniprotkb:Q9NQD9|uniprotkb:Q6I9Y7|uniprotkb:B3KXE0|uniprotkb:D3DQY2|ensembl:ENSP00000265963|ensembl:ENSP00000393638|ensembl:ENSP00000500178|ensembl:ENSP00000500852 psi-mi:tf2h3_human(display_long)|uniprotkb:GTF2H3(gene name)|psi-mi:GTF2H3(display_short)|uniprotkb:Basic transcription factor 2 34 kDa subunit(gene name synonym)|uniprotkb:General transcription factor IIH polypeptide 3(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p34 subunit(gene name synonym) psi-mi:tf2h1_human(display_long)|uniprotkb:General transcription factor IIH polypeptide 1(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p62 subunit(gene name synonym)|uniprotkb:Basic transcription factor 2 62 kDa subunit(gene name synonym)|uniprotkb:GTF2H1(gene name)|psi-mi:GTF2H1(display_short)|uniprotkb:BTF2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478913|imex:IM-26985-473 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000111358(gene)|ensembl:ENST00000543341(transcript)|go:"GO:0000438"(core TFIIH complex portion of holo TFIIH complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR004600(Transcription factor Tfb4)|interpro:IPR036465|mint:Q13889|rcsb pdb:5IVW|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5O85|rcsb pdb:5OF4|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:6RO4|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-75955|dip:DIP-787N|refseq:NP_001258795.1|refseq:NP_001258796.1|refseq:NP_001258797.1|refseq:NP_001507.2 refseq:NP_001135779.1|refseq:NP_005307.1|ensembl:ENSG00000110768(gene)|ensembl:ENSG00000288114(gene)|ensembl:ENST00000265963(transcript)|ensembl:ENST00000453096(transcript)|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|ensembl:ENST00000672827(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR005607(BSD)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013876(TFIIH p62 subunit, N-terminal)|interpro:IPR027079|interpro:IPR035925|mint:P32780|rcsb pdb:1PFJ|rcsb pdb:2DII|rcsb pdb:2RNR|rcsb pdb:2RUK|rcsb pdb:2RVB|rcsb pdb:5GOW|rcsb pdb:5XV8|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:7BUL|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|ensembl:ENST00000672527(transcript)|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|refseq:XP_006718271.1|dip:DIP-708N - - comment:"author score: 165" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Ca5tFYnStJdHF1eNPEwLZtKB0+09606 rogid:X5tWUeZYcYgB31HZSn8Ndi9w3V89606 rigid:wqT/KDP+JNu9r/U0GuCexKDfa80 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13889 uniprotkb:P19447 intact:EBI-6380459|uniprotkb:B4DNZ6|ensembl:ENSP00000445162|uniprotkb:B2R819|uniprotkb:Q7L0G0|uniprotkb:Q96AT7 intact:EBI-1183307|uniprotkb:Q53QM0|ensembl:ENSP00000285398 psi-mi:tf2h3_human(display_long)|uniprotkb:GTF2H3(gene name)|psi-mi:GTF2H3(display_short)|uniprotkb:Basic transcription factor 2 34 kDa subunit(gene name synonym)|uniprotkb:General transcription factor IIH polypeptide 3(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p34 subunit(gene name synonym) psi-mi:ercc3_human(display_long)|uniprotkb:ERCC3(gene name)|psi-mi:ERCC3(display_short)|uniprotkb:XPB(gene name synonym)|uniprotkb:XPBC(gene name synonym)|uniprotkb:Basic transcription factor 2 89 kDa subunit(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex 89 kDa subunit(gene name synonym)|uniprotkb:DNA repair protein complementing XP-B cells(gene name synonym)|uniprotkb:Xeroderma pigmentosum group B-complementing protein(gene name synonym)|uniprotkb:DNA excision repair protein ERCC-3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478913|imex:IM-26985-473 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000111358(gene)|ensembl:ENST00000543341(transcript)|go:"GO:0000438"(core TFIIH complex portion of holo TFIIH complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR004600(Transcription factor Tfb4)|interpro:IPR036465|mint:Q13889|rcsb pdb:5IVW|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5O85|rcsb pdb:5OF4|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:6RO4|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-75955|dip:DIP-787N|refseq:NP_001258795.1|refseq:NP_001258796.1|refseq:NP_001258797.1|refseq:NP_001507.2 refseq:NP_000113.1|ensembl:ENSG00000163161(gene)|ensembl:ENST00000285398(transcript)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0000717"(nucleotide-excision repair, DNA duplex unwinding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006265"(DNA topological change)|go:"GO:0006281"(DNA repair)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006915"(apoptotic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0009411"(response to UV)|go:"GO:0009650"(UV protection)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0033683"(nucleotide-excision repair, DNA incision)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048568"(embryonic organ development)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001161("Xeroderma pigmentosum group B protein (XP-B)")|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR032438|interpro:IPR032830|mint:P19447|rcsb pdb:4ERN|rcsb pdb:5IVW|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5OF4|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:6RO4|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVV|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-73863|dip:DIP-83N - - comment:"author score: 175" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Ca5tFYnStJdHF1eNPEwLZtKB0+09606 rogid:KOM9+f636LHK8qfTFkLIm0X0VoY9606 rigid:wqT/KDP+JNu9r/U0GuCexKDfa80 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TDG4 uniprotkb:P84090 intact:EBI-2802156|uniprotkb:Q659B8|uniprotkb:Q96EX7|uniprotkb:Q502W9|uniprotkb:Q6ZQX4|uniprotkb:Q6ZTS4|uniprotkb:Q05DF9|ensembl:ENSP00000295488 intact:EBI-711389|uniprotkb:P70659|uniprotkb:Q14259|ensembl:ENSP00000451080|uniprotkb:B2R5H2 psi-mi:helq_human(display_long)|uniprotkb:HEL308(gene name synonym)|uniprotkb:Mus308-like helicase(gene name synonym)|uniprotkb:POLQ-like helicase(gene name synonym)|uniprotkb:HELQ(gene name)|psi-mi:HELQ(display_short) psi-mi:erh_human(display_long)|uniprotkb:ERH(gene name)|psi-mi:ERH(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479159|imex:IM-26985-403 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001284687.1|refseq:NP_001284688.1|refseq:NP_598375.2|ensembl:ENST00000295488(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006364"(rRNA processing)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990518"(single-stranded 3'-5' DNA helicase activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR036390|mint:Q8TDG4|ensembl:ENSG00000163312(gene)|dip:DIP-60603N ensembl:ENSG00000100632(gene)|ensembl:ENST00000557016(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006213"(pyrimidine nucleoside metabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0030496"(midbody)|go:"GO:0034709"(methylosome)|interpro:IPR000781(Enhancer of rudimentary)|interpro:IPR035912|mint:P84090|rcsb pdb:1W9G|rcsb pdb:2NML|rcsb pdb:7CNC|refseq:NP_004441.1|dip:DIP-42473N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ATANu7auxIdDZnVgehEdEOodUJ89606 rogid:foMOmvZ9wQyH0rrzBB2YlQhrT0g9606 rigid:lfFlwbyNqgS4NXd5V4WUU7Fd6eE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TDG4 uniprotkb:P68363 intact:EBI-2802156|uniprotkb:Q659B8|uniprotkb:Q96EX7|uniprotkb:Q502W9|uniprotkb:Q6ZQX4|uniprotkb:Q6ZTS4|uniprotkb:Q05DF9|ensembl:ENSP00000295488 intact:EBI-487083|intact:EBI-1384226|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:Q27I68|ensembl:ENSP00000336799|uniprotkb:Q8WU19 psi-mi:helq_human(display_long)|uniprotkb:HEL308(gene name synonym)|uniprotkb:Mus308-like helicase(gene name synonym)|uniprotkb:POLQ-like helicase(gene name synonym)|uniprotkb:HELQ(gene name)|psi-mi:HELQ(display_short) psi-mi:tba1b_human(display_long)|uniprotkb:TUBA1B(gene name)|psi-mi:TUBA1B(display_short)|uniprotkb:Tubulin alpha-ubiquitous chain(gene name synonym)|uniprotkb:Alpha-tubulin ubiquitous(gene name synonym)|uniprotkb:Tubulin K-alpha-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479159|imex:IM-26985-403 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001284687.1|refseq:NP_001284688.1|refseq:NP_598375.2|ensembl:ENST00000295488(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006364"(rRNA processing)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990518"(single-stranded 3'-5' DNA helicase activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR036390|mint:Q8TDG4|ensembl:ENSG00000163312(gene)|dip:DIP-60603N refseq:NP_006073.2|ensembl:ENSG00000123416(gene)|ensembl:ENST00000336023(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-983189|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|go:"GO:0045121"(membrane raft)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68363|rcsb pdb:2E4H|rcsb pdb:5IJ0|rcsb pdb:5IJ9|rcsb pdb:5N5N|rcsb pdb:6E7B|rcsb pdb:6E7C|rcsb pdb:6I2I|go:"GO:0051301"(cell division)|rcsb pdb:6J4V|rcsb pdb:6J8O|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|rcsb pdb:6S8L|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9013407|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-2132295|reactome:R-HSA-9668328 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ATANu7auxIdDZnVgehEdEOodUJ89606 rogid:D4YpuLCXl/S+53qV7P7sF81aARY9606 rigid:lfFlwbyNqgS4NXd5V4WUU7Fd6eE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TDG4 uniprotkb:P62805 intact:EBI-2802156|uniprotkb:Q659B8|uniprotkb:Q96EX7|uniprotkb:Q502W9|uniprotkb:Q6ZQX4|uniprotkb:Q6ZTS4|uniprotkb:Q05DF9|ensembl:ENSP00000295488 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:helq_human(display_long)|uniprotkb:HEL308(gene name synonym)|uniprotkb:Mus308-like helicase(gene name synonym)|uniprotkb:POLQ-like helicase(gene name synonym)|uniprotkb:HELQ(gene name)|psi-mi:HELQ(display_short) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479159|imex:IM-26985-403 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001284687.1|refseq:NP_001284688.1|refseq:NP_598375.2|ensembl:ENST00000295488(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006364"(rRNA processing)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990518"(single-stranded 3'-5' DNA helicase activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR036390|mint:Q8TDG4|ensembl:ENSG00000163312(gene)|dip:DIP-60603N ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ATANu7auxIdDZnVgehEdEOodUJ89606 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 rigid:lfFlwbyNqgS4NXd5V4WUU7Fd6eE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13547 uniprotkb:O15212 intact:EBI-301834|uniprotkb:Q92534|ensembl:ENSP00000362649 intact:EBI-356973|ensembl:ENSP00000363734|ensembl:ENSP00000363735|ensembl:ENSP00000363738|ensembl:ENSP00000372694|ensembl:ENSP00000378563|ensembl:ENSP00000382314|ensembl:ENSP00000382316|ensembl:ENSP00000395462|ensembl:ENSP00000398171|ensembl:ENSP00000400152|ensembl:ENSP00000402212|ensembl:ENSP00000402553|ensembl:ENSP00000403771|ensembl:ENSP00000404773|ensembl:ENSP00000412319|ensembl:ENSP00000415678|ensembl:ENSP00000447540|ensembl:ENSP00000448607|ensembl:ENSP00000448784|ensembl:ENSP00000449925 psi-mi:hdac1_human(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short)|uniprotkb:RPD3L1(gene name synonym) psi-mi:pfd6_human(display_long)|uniprotkb:PFDN6(gene name)|psi-mi:PFDN6(display_short)|uniprotkb:HKE2(gene name synonym)|uniprotkb:PFD6(gene name synonym)|uniprotkb:Protein Ke2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479132|imex:IM-26985-245 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000116478(gene)|ensembl:ENST00000373548(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001975"(response to amphetamine)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007492"(endoderm development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031000"(response to caffeine)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043044"|go:"GO:0019213"(deacetylase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900221"(regulation of amyloid-beta clearance)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q13547|rcsb pdb:1TYI|rcsb pdb:4BKX|rcsb pdb:5ICN|rcsb pdb:6Z2J|rcsb pdb:6Z2K|rcsb pdb:7AO8|rcsb pdb:7AO9|rcsb pdb:7AOA|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-193670|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-3769402|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-4641265|reactome:R-HSA-6804758|reactome:R-HSA-69205|reactome:R-HSA-73762|reactome:R-HSA-8936459|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9022538|reactome:R-HSA-9022692|go:"GO:0017053"(transcription repressor complex)|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-9022699|reactome:R-HSA-9022702|reactome:R-HSA-9615017|reactome:R-HSA-9679191|reactome:R-HSA-983231|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:NP_004955.2|dip:DIP-24184N refseq:NP_001172110.1|refseq:NP_055075.1|refseq:NP_001252524.1|refseq:NP_001252525.1|dip:DIP-50304N|ensembl:ENSG00000204220(gene)|ensembl:ENSG00000206283(gene)|ensembl:ENSG00000224782(gene)|ensembl:ENSG00000235692(gene)|ensembl:ENSG00000237335(gene)|ensembl:ENST00000374606(transcript)|ensembl:ENST00000374607(transcript)|ensembl:ENST00000374610(transcript)|ensembl:ENST00000383207(transcript)|ensembl:ENST00000395131(transcript)|ensembl:ENST00000399383(transcript)|ensembl:ENST00000399385(transcript)|ensembl:ENST00000412289(transcript)|ensembl:ENST00000425878(transcript)|ensembl:ENST00000431830(transcript)|ensembl:ENST00000432391(transcript)|ensembl:ENST00000442285(transcript)|ensembl:ENST00000445559(transcript)|ensembl:ENST00000448594(transcript)|ensembl:ENST00000451970(transcript)|ensembl:ENST00000452658(transcript)|ensembl:ENST00000547641(transcript)|ensembl:ENST00000547952(transcript)|ensembl:ENST00000548040(transcript)|ensembl:ENST00000552711(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|mint:O15212|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957 - - crc64:8F138EAAE512A312|comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RP+yIBWH55NgoPTY1nKXqeJL/xY9606 rogid:t7Z68vuvmprxLIGDh4JhqCGvX+A9606 rigid:hQKHaeiSYgc4WIUSjtC4LF6Q3Yo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13547 uniprotkb:O60925 intact:EBI-301834|uniprotkb:Q92534|ensembl:ENSP00000362649 intact:EBI-356919|uniprotkb:Q53F95|uniprotkb:Q96EX6|uniprotkb:B2RD02|ensembl:ENSP00000261813 psi-mi:hdac1_human(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short)|uniprotkb:RPD3L1(gene name synonym) psi-mi:pfd1_human(display_long)|uniprotkb:PFDN1(gene name)|psi-mi:PFDN1(display_short)|uniprotkb:PFD1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479132|imex:IM-26985-245 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000116478(gene)|ensembl:ENST00000373548(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001975"(response to amphetamine)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007492"(endoderm development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031000"(response to caffeine)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043044"|go:"GO:0019213"(deacetylase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900221"(regulation of amyloid-beta clearance)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q13547|rcsb pdb:1TYI|rcsb pdb:4BKX|rcsb pdb:5ICN|rcsb pdb:6Z2J|rcsb pdb:6Z2K|rcsb pdb:7AO8|rcsb pdb:7AO9|rcsb pdb:7AOA|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-193670|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-3769402|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-4641265|reactome:R-HSA-6804758|reactome:R-HSA-69205|reactome:R-HSA-73762|reactome:R-HSA-8936459|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9022538|reactome:R-HSA-9022692|go:"GO:0017053"(transcription repressor complex)|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-9022699|reactome:R-HSA-9022702|reactome:R-HSA-9615017|reactome:R-HSA-9679191|reactome:R-HSA-983231|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:NP_004955.2|dip:DIP-24184N refseq:NP_002613.2|ensembl:ENSG00000113068(gene)|ensembl:ENST00000261813(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|mint:O60925|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RP+yIBWH55NgoPTY1nKXqeJL/xY9606 rogid:repqo0hQgD7XgRAZll8ucK2jwz49606 rigid:hQKHaeiSYgc4WIUSjtC4LF6Q3Yo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13547 uniprotkb:Q09028 intact:EBI-301834|uniprotkb:Q92534|ensembl:ENSP00000362649 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 psi-mi:hdac1_human(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short)|uniprotkb:RPD3L1(gene name synonym) psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479132|imex:IM-26985-245 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000116478(gene)|ensembl:ENST00000373548(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001975"(response to amphetamine)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007492"(endoderm development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031000"(response to caffeine)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043044"|go:"GO:0019213"(deacetylase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900221"(regulation of amyloid-beta clearance)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q13547|rcsb pdb:1TYI|rcsb pdb:4BKX|rcsb pdb:5ICN|rcsb pdb:6Z2J|rcsb pdb:6Z2K|rcsb pdb:7AO8|rcsb pdb:7AO9|rcsb pdb:7AOA|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-193670|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-3769402|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-4641265|reactome:R-HSA-6804758|reactome:R-HSA-69205|reactome:R-HSA-73762|reactome:R-HSA-8936459|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9022538|reactome:R-HSA-9022692|go:"GO:0017053"(transcription repressor complex)|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-9022699|reactome:R-HSA-9022702|reactome:R-HSA-9615017|reactome:R-HSA-9679191|reactome:R-HSA-983231|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:NP_004955.2|dip:DIP-24184N ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RP+yIBWH55NgoPTY1nKXqeJL/xY9606 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rigid:hQKHaeiSYgc4WIUSjtC4LF6Q3Yo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13547 uniprotkb:Q9UHV9 intact:EBI-301834|uniprotkb:Q92534|ensembl:ENSP00000362649 intact:EBI-359873|uniprotkb:Q9P0P7|uniprotkb:Q9UN05|ensembl:ENSP00000356989 psi-mi:hdac1_human(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short)|uniprotkb:RPD3L1(gene name synonym) psi-mi:pfd2_human(display_long)|uniprotkb:HSPC231(orf name)|uniprotkb:PFDN2(gene name)|psi-mi:PFDN2(display_short)|uniprotkb:PFD2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479132|imex:IM-26985-245 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000116478(gene)|ensembl:ENST00000373548(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001975"(response to amphetamine)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007492"(endoderm development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031000"(response to caffeine)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043044"|go:"GO:0019213"(deacetylase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900221"(regulation of amyloid-beta clearance)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q13547|rcsb pdb:1TYI|rcsb pdb:4BKX|rcsb pdb:5ICN|rcsb pdb:6Z2J|rcsb pdb:6Z2K|rcsb pdb:7AO8|rcsb pdb:7AO9|rcsb pdb:7AOA|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-193670|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-3769402|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-4641265|reactome:R-HSA-6804758|reactome:R-HSA-69205|reactome:R-HSA-73762|reactome:R-HSA-8936459|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9022538|reactome:R-HSA-9022692|go:"GO:0017053"(transcription repressor complex)|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-9022699|reactome:R-HSA-9022702|reactome:R-HSA-9615017|reactome:R-HSA-9679191|reactome:R-HSA-983231|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:NP_004955.2|dip:DIP-24184N refseq:NP_036526.2|refseq:XP_011507926.1|ensembl:ENSG00000143256(gene)|ensembl:ENST00000368010(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|interpro:IPR027235|mint:Q9UHV9|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957|dip:DIP-27557N - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RP+yIBWH55NgoPTY1nKXqeJL/xY9606 rogid:rgr14h3vGyzHxHoNJtlHBQkvhUE9606 rigid:hQKHaeiSYgc4WIUSjtC4LF6Q3Yo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13547 uniprotkb:P61758 intact:EBI-301834|uniprotkb:Q92534|ensembl:ENSP00000362649 intact:EBI-357430|ensembl:ENSP00000286428|uniprotkb:Q15765|uniprotkb:O55228|uniprotkb:Q5JT81|uniprotkb:Q86X96|uniprotkb:B2R8L5|uniprotkb:B4DWR3|uniprotkb:F5H2A7 psi-mi:hdac1_human(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short)|uniprotkb:RPD3L1(gene name synonym) psi-mi:pfd3_human(display_long)|uniprotkb:VBP1(gene name)|psi-mi:VBP1(display_short)|uniprotkb:PFDN3(gene name synonym)|uniprotkb:von Hippel-Lindau-binding protein 1(gene name synonym)|uniprotkb:HIBBJ46(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479132|imex:IM-26985-245 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000116478(gene)|ensembl:ENST00000373548(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001975"(response to amphetamine)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007492"(endoderm development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031000"(response to caffeine)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043044"|go:"GO:0019213"(deacetylase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900221"(regulation of amyloid-beta clearance)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q13547|rcsb pdb:1TYI|rcsb pdb:4BKX|rcsb pdb:5ICN|rcsb pdb:6Z2J|rcsb pdb:6Z2K|rcsb pdb:7AO8|rcsb pdb:7AO9|rcsb pdb:7AOA|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-193670|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-3769402|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-4641265|reactome:R-HSA-6804758|reactome:R-HSA-69205|reactome:R-HSA-73762|reactome:R-HSA-8936459|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9022538|reactome:R-HSA-9022692|go:"GO:0017053"(transcription repressor complex)|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-9022699|reactome:R-HSA-9022702|reactome:R-HSA-9615017|reactome:R-HSA-9679191|reactome:R-HSA-983231|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:NP_004955.2|dip:DIP-24184N ensembl:ENSG00000155959(gene)|ensembl:ENST00000286428(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006457"(protein folding)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR016655(Prefoldin, subunit 3)|mint:P61758|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957|refseq:NP_003363.1|refseq:NP_001290472.1|refseq:NP_001290474.1|dip:DIP-46479N|refseq:NP_001290473.1 - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RP+yIBWH55NgoPTY1nKXqeJL/xY9606 rogid:wHq+HRvhqfKwOaKtONGJdfETQxo9606 rigid:hQKHaeiSYgc4WIUSjtC4LF6Q3Yo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13547 uniprotkb:Q99471 intact:EBI-301834|uniprotkb:Q92534|ensembl:ENSP00000362649 intact:EBI-357275|ensembl:ENSP00000334188|ensembl:ENSP00000447942|intact:EBI-1047551|uniprotkb:A8K9A8|uniprotkb:Q54AA8|uniprotkb:Q9C083|uniprotkb:Q9C084 psi-mi:hdac1_human(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short)|uniprotkb:RPD3L1(gene name synonym) psi-mi:pfd5_human(display_long)|uniprotkb:c-Myc-binding protein Mm-1(gene name synonym)|uniprotkb:PFDN5(gene name)|psi-mi:PFDN5(display_short)|uniprotkb:MM1(gene name synonym)|uniprotkb:Myc modulator 1(gene name synonym)|uniprotkb:PFD5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479132|imex:IM-26985-245 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000116478(gene)|ensembl:ENST00000373548(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001975"(response to amphetamine)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007492"(endoderm development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031000"(response to caffeine)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043044"|go:"GO:0019213"(deacetylase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900221"(regulation of amyloid-beta clearance)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q13547|rcsb pdb:1TYI|rcsb pdb:4BKX|rcsb pdb:5ICN|rcsb pdb:6Z2J|rcsb pdb:6Z2K|rcsb pdb:7AO8|rcsb pdb:7AO9|rcsb pdb:7AOA|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-193670|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-3769402|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-4641265|reactome:R-HSA-6804758|reactome:R-HSA-69205|reactome:R-HSA-73762|reactome:R-HSA-8936459|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9022538|reactome:R-HSA-9022692|go:"GO:0017053"(transcription repressor complex)|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-9022699|reactome:R-HSA-9022702|reactome:R-HSA-9615017|reactome:R-HSA-9679191|reactome:R-HSA-983231|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:NP_004955.2|dip:DIP-24184N ensembl:ENSG00000123349(gene)|ensembl:ENST00000334478(transcript)|ensembl:ENST00000551018(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR011599(Prefoldin alpha subunit)|mint:Q99471|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957|refseq:NP_002615.2|refseq:NP_665904.1|dip:DIP-28155N - - comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RP+yIBWH55NgoPTY1nKXqeJL/xY9606 rogid:Cm4km207qcfDJYRUCIwUxMBT4tE9606 rigid:hQKHaeiSYgc4WIUSjtC4LF6Q3Yo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13547 uniprotkb:Q92769 intact:EBI-301834|uniprotkb:Q92534|ensembl:ENSP00000362649 intact:EBI-301821|uniprotkb:Q5SRI8|uniprotkb:Q5SZ86|uniprotkb:Q8NEH4|uniprotkb:B4DL58|ensembl:ENSP00000430432|uniprotkb:E1P561|uniprotkb:B3KRS5 psi-mi:hdac1_human(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short)|uniprotkb:RPD3L1(gene name synonym) psi-mi:hdac2_human(display_long)|uniprotkb:HDAC2(gene name)|psi-mi:HDAC2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479132|imex:IM-26985-245 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000116478(gene)|ensembl:ENST00000373548(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001975"(response to amphetamine)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007492"(endoderm development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031000"(response to caffeine)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043044"|go:"GO:0019213"(deacetylase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900221"(regulation of amyloid-beta clearance)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q13547|rcsb pdb:1TYI|rcsb pdb:4BKX|rcsb pdb:5ICN|rcsb pdb:6Z2J|rcsb pdb:6Z2K|rcsb pdb:7AO8|rcsb pdb:7AO9|rcsb pdb:7AOA|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-193670|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-3769402|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-4641265|reactome:R-HSA-6804758|reactome:R-HSA-69205|reactome:R-HSA-73762|reactome:R-HSA-8936459|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9022538|reactome:R-HSA-9022692|go:"GO:0017053"(transcription repressor complex)|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-9022699|reactome:R-HSA-9022702|reactome:R-HSA-9615017|reactome:R-HSA-9679191|reactome:R-HSA-983231|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:NP_004955.2|dip:DIP-24184N go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035094"(response to nicotine)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042220"(response to cocaine)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q92769|rcsb pdb:3MAX|rcsb pdb:4LXZ|rcsb pdb:4LY1|rcsb pdb:5IWG|rcsb pdb:5IX0|rcsb pdb:6G3O|rcsb pdb:6WBW|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|ensembl:ENSG00000196591(gene)|ensembl:ENST00000519065(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|rcsb pdb:6WHN|rcsb pdb:6WHO|rcsb pdb:6WHQ|rcsb pdb:6WHZ|rcsb pdb:6WI3|rcsb pdb:6XDM|rcsb pdb:6XEB|rcsb pdb:6XEC|rcsb pdb:7KBG|rcsb pdb:7KBH|rcsb pdb:7LTG|rcsb pdb:7LTK|rcsb pdb:7LTL|reactome:R-HSA-193670|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9615017|reactome:R-HSA-9619665|reactome:R-HSA-9679191|reactome:R-HSA-983231|rcsb pdb:6WBZ|refseq:NP_001518.3|dip:DIP-24220N|refseq:XP_011534090.1|refseq:XP_016866288.1 - - comment:"author score: 60" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RP+yIBWH55NgoPTY1nKXqeJL/xY9606 rogid:K4PpGz9E9/TrQZsgvrJuc+uYCn89606 rigid:hQKHaeiSYgc4WIUSjtC4LF6Q3Yo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BT25 uniprotkb:O75947 intact:EBI-2558143|uniprotkb:B4DJA7|uniprotkb:Q86WF0|uniprotkb:Q49AC4|intact:EBI-2562724|uniprotkb:Q96FX3|uniprotkb:C9JBZ4|intact:EBI-11024560|ensembl:ENSP00000253669 intact:EBI-724024|ensembl:ENSP00000301587|uniprotkb:Q9H3J4|uniprotkb:B2R5L6 psi-mi:haus8_human(display_long)|uniprotkb:HICE1(gene name synonym)|uniprotkb:HEC1/NDC80-interacting centrosome-associated protein 1(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-48(gene name synonym)|uniprotkb:HAUS8(gene name)|psi-mi:HAUS8(display_short) psi-mi:atp5h_human(display_long)|uniprotkb:ATP5PD(gene name)|psi-mi:ATP5PD(display_short)|uniprotkb:ATP synthase peripheral stalk subunit d(gene name synonym)|uniprotkb:ATP5H(gene name synonym)|uniprotkb:My032(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479096|imex:IM-26985-401 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_219485.1|refseq:NP_001011699.1|dip:DIP-48834N|ensembl:ENSG00000131351(gene)|ensembl:ENST00000253669(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005880"(nuclear microtubule)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|mint:Q9BT25|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518 refseq:NP_001003785.1|refseq:NP_006347.1|ensembl:ENSG00000167863(gene)|ensembl:ENST00000301587(transcript)|go:"GO:0000274"(mitochondrial proton-transporting ATP synthase, stator stalk)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|interpro:IPR008689(ATPase, F0 complex, subunit D, mitochondrial)|interpro:IPR036228|mint:O75947|reactome:R-HSA-163210|reactome:R-HSA-8949613 - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:q+J6qqmCxKWrUiWL50GtzEq9+AM9606 rogid:GFk/w7iWIjum9BpZs8ZlPrM5kBs9606 rigid:WXZbxeJ/F+j8VN0lIPi48uiE+G4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BT25 uniprotkb:Q96A65 intact:EBI-2558143|uniprotkb:B4DJA7|uniprotkb:Q86WF0|uniprotkb:Q49AC4|intact:EBI-2562724|uniprotkb:Q96FX3|uniprotkb:C9JBZ4|intact:EBI-11024560|ensembl:ENSP00000253669 intact:EBI-355383|intact:EBI-1058596|uniprotkb:Q9C0G4|uniprotkb:Q9H9K0|uniprotkb:Q9P102|uniprotkb:Q541U8|uniprotkb:E9PED2|ensembl:ENSP00000253861 psi-mi:haus8_human(display_long)|uniprotkb:HICE1(gene name synonym)|uniprotkb:HEC1/NDC80-interacting centrosome-associated protein 1(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-48(gene name synonym)|uniprotkb:HAUS8(gene name)|psi-mi:HAUS8(display_short) psi-mi:exoc4_human(display_long)|uniprotkb:EXOC4(gene name)|psi-mi:EXOC4(display_short)|uniprotkb:KIAA1699(gene name synonym)|uniprotkb:SEC8(gene name synonym)|uniprotkb:SEC8L1(gene name synonym)|uniprotkb:Exocyst complex component Sec8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479096|imex:IM-26985-401 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_219485.1|refseq:NP_001011699.1|dip:DIP-48834N|ensembl:ENSG00000131351(gene)|ensembl:ENST00000253669(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005880"(nuclear microtubule)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|mint:Q9BT25|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518 refseq:NP_068579.3|dip:DIP-32976N|ensembl:ENSG00000131558(gene)|ensembl:ENST00000253861(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032584"(growth cone membrane)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048341"(paraxial mesoderm formation)|go:"GO:0090543"(Flemming body)|interpro:IPR007191(Sec8 exocyst complex component specific domain)|interpro:IPR039682|mint:Q96A65|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|go:"GO:0090522"(vesicle tethering involved in exocytosis) - - comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:q+J6qqmCxKWrUiWL50GtzEq9+AM9606 rogid:cISO7v2OxFaDg0qe9XNV0Qoyby89606 rigid:WXZbxeJ/F+j8VN0lIPi48uiE+G4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BT25 uniprotkb:Q9Y6H1 intact:EBI-2558143|uniprotkb:B4DJA7|uniprotkb:Q86WF0|uniprotkb:Q49AC4|intact:EBI-2562724|uniprotkb:Q96FX3|uniprotkb:C9JBZ4|intact:EBI-11024560|ensembl:ENSP00000253669 intact:EBI-2321769|uniprotkb:Q498C3|uniprotkb:Q6NZ50|ensembl:ENSP00000378812 psi-mi:haus8_human(display_long)|uniprotkb:HICE1(gene name synonym)|uniprotkb:HEC1/NDC80-interacting centrosome-associated protein 1(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-48(gene name synonym)|uniprotkb:HAUS8(gene name)|psi-mi:HAUS8(display_short) psi-mi:chch2_human(display_long)|uniprotkb:CHCHD2(gene name)|psi-mi:CHCHD2(display_short)|uniprotkb:C7orf17(gene name synonym)|uniprotkb:HCV NS2 trans-regulated protein(gene name synonym)|uniprotkb:Aging-associated gene 10 protein(gene name synonym)|uniprotkb:AAG10(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479096|imex:IM-26985-401 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_219485.1|refseq:NP_001011699.1|dip:DIP-48834N|ensembl:ENSG00000131351(gene)|ensembl:ENST00000253669(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005880"(nuclear microtubule)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|mint:Q9BT25|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518 refseq:NP_057223.1|ensembl:ENSG00000106153(gene)|ensembl:ENST00000395422(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900037"(regulation of cellular response to hypoxia)|go:"GO:1905448"(positive regulation of mitochondrial ATP synthesis coupled electron transport)|interpro:IPR010625(CHCH)|mint:Q9Y6H1|reactome:R-HSA-1268020 - - comment:"author score: 33" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:q+J6qqmCxKWrUiWL50GtzEq9+AM9606 rogid:fdx3lE51+yZ1k3uwh8/LDKJC+CQ9606 rigid:WXZbxeJ/F+j8VN0lIPi48uiE+G4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BT25 uniprotkb:Q8N257 intact:EBI-2558143|uniprotkb:B4DJA7|uniprotkb:Q86WF0|uniprotkb:Q49AC4|intact:EBI-2562724|uniprotkb:Q96FX3|uniprotkb:C9JBZ4|intact:EBI-11024560|ensembl:ENSP00000253669 intact:EBI-6150245|uniprotkb:Q5TA30|uniprotkb:Q3ZCP6|uniprotkb:A4FU05|ensembl:ENSP00000479284|ensembl:ENSP00000496342 psi-mi:haus8_human(display_long)|uniprotkb:HICE1(gene name synonym)|uniprotkb:HEC1/NDC80-interacting centrosome-associated protein 1(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-48(gene name synonym)|uniprotkb:HAUS8(gene name)|psi-mi:HAUS8(display_short) psi-mi:h2b3b_human(display_long)|uniprotkb:H2BU1(gene name)|psi-mi:H2BU1(display_short)|uniprotkb:H2B type 12(gene name synonym)|uniprotkb:H2B.U histone 1(gene name synonym)|uniprotkb:HIST3H2BB(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479096|imex:IM-26985-401 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_219485.1|refseq:NP_001011699.1|dip:DIP-48834N|ensembl:ENSG00000131351(gene)|ensembl:ENST00000253669(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005880"(nuclear microtubule)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|mint:Q9BT25|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518 refseq:NP_778225.1|ensembl:ENSG00000196890(gene)|ensembl:ENSG00000285449(gene)|ensembl:ENST00000620438(transcript)|ensembl:ENST00000647549(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:Q8N257|rcsb pdb:6BIZ|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - comment:"author score: 34" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:q+J6qqmCxKWrUiWL50GtzEq9+AM9606 rogid:MnRK2NXd2p3rWO8GPfErAa273eY9606 rigid:WXZbxeJ/F+j8VN0lIPi48uiE+G4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BT25 uniprotkb:Q99871 intact:EBI-2558143|uniprotkb:B4DJA7|uniprotkb:Q86WF0|uniprotkb:Q49AC4|intact:EBI-2562724|uniprotkb:Q96FX3|uniprotkb:C9JBZ4|intact:EBI-11024560|ensembl:ENSP00000253669 intact:EBI-395719|uniprotkb:Q96HS8|uniprotkb:Q9NP54|uniprotkb:D3DWT9|intact:EBI-2558192|uniprotkb:B4DUH6|uniprotkb:Q9UFH9|ensembl:ENSP00000359230 psi-mi:haus8_human(display_long)|uniprotkb:HICE1(gene name synonym)|uniprotkb:HEC1/NDC80-interacting centrosome-associated protein 1(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-48(gene name synonym)|uniprotkb:HAUS8(gene name)|psi-mi:HAUS8(display_short) psi-mi:haus7_human(display_long)|uniprotkb:HAUS7(gene name)|psi-mi:HAUS7(display_short)|uniprotkb:26S proteasome-associated UCH37-interacting protein 1(gene name synonym)|uniprotkb:X-linked protein STS1769(gene name synonym)|uniprotkb:UIP1(gene name synonym)|uniprotkb:UCHL5IP(gene name synonym)|uniprotkb:UCHL5-interacting protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479096|imex:IM-26985-401 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_219485.1|refseq:NP_001011699.1|dip:DIP-48834N|ensembl:ENSG00000131351(gene)|ensembl:ENST00000253669(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005880"(nuclear microtubule)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|mint:Q9BT25|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518 refseq:NP_059988.3|dip:DIP-32974N|ensembl:ENSG00000213397(gene)|ensembl:ENST00000370211(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0031996"(thioesterase binding)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR029711|mint:Q99871|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518 - - comment:"author score: 222" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:q+J6qqmCxKWrUiWL50GtzEq9+AM9606 rogid:nDQXUt43VCTD0vyH0M8OAsGJbEY9606 rigid:WXZbxeJ/F+j8VN0lIPi48uiE+G4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BT25 uniprotkb:Q96CS2 intact:EBI-2558143|uniprotkb:B4DJA7|uniprotkb:Q86WF0|uniprotkb:Q49AC4|intact:EBI-2562724|uniprotkb:Q96FX3|uniprotkb:C9JBZ4|intact:EBI-11024560|ensembl:ENSP00000253669 intact:EBI-2514791|ensembl:ENSP00000282058|uniprotkb:Q8N837|uniprotkb:B2RDM7 psi-mi:haus8_human(display_long)|uniprotkb:HICE1(gene name synonym)|uniprotkb:HEC1/NDC80-interacting centrosome-associated protein 1(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-48(gene name synonym)|uniprotkb:HAUS8(gene name)|psi-mi:HAUS8(display_short) psi-mi:haus1_human(display_long)|uniprotkb:HAUS1(gene name)|psi-mi:HAUS1(display_short)|uniprotkb:CCDC5(gene name synonym)|uniprotkb:HEIC(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 5(gene name synonym)|uniprotkb:Enhancer of invasion-cluster(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479096|imex:IM-26985-401 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_219485.1|refseq:NP_001011699.1|dip:DIP-48834N|ensembl:ENSG00000131351(gene)|ensembl:ENST00000253669(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005880"(nuclear microtubule)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|mint:Q9BT25|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518 ensembl:ENSG00000152240(gene)|ensembl:ENST00000282058(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR026243|mint:Q96CS2|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_612452.1|dip:DIP-48835N - - comment:"author score: 226" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:q+J6qqmCxKWrUiWL50GtzEq9+AM9606 rogid:U+lgSilH3iBIHBktPv30KtUnDPg9606 rigid:WXZbxeJ/F+j8VN0lIPi48uiE+G4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BT25 uniprotkb:O94927 intact:EBI-2558143|uniprotkb:B4DJA7|uniprotkb:Q86WF0|uniprotkb:Q49AC4|intact:EBI-2562724|uniprotkb:Q96FX3|uniprotkb:C9JBZ4|intact:EBI-11024560|ensembl:ENSP00000253669 intact:EBI-2558224|uniprotkb:B2RXK1|uniprotkb:Q6P2P7|uniprotkb:Q96CT8|uniprotkb:Q7L3D5|ensembl:ENSP00000439056 psi-mi:haus8_human(display_long)|uniprotkb:HICE1(gene name synonym)|uniprotkb:HEC1/NDC80-interacting centrosome-associated protein 1(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-48(gene name synonym)|uniprotkb:HAUS8(gene name)|psi-mi:HAUS8(display_short) psi-mi:haus5_human(display_long)|uniprotkb:HAUS5(gene name)|psi-mi:HAUS5(display_short)|uniprotkb:KIAA0841(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479096|imex:IM-26985-401 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_219485.1|refseq:NP_001011699.1|dip:DIP-48834N|ensembl:ENSG00000131351(gene)|ensembl:ENST00000253669(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005880"(nuclear microtubule)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|mint:Q9BT25|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518 refseq:NP_056117.1|ensembl:ENSG00000249115(gene)|ensembl:ENST00000203166(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR026215|interpro:IPR029131|mint:O94927|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|dip:DIP-48831N - - comment:"author score: 229" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:q+J6qqmCxKWrUiWL50GtzEq9+AM9606 rogid:ChAZl+X89FxK08LHh2+lYDqQZn09606 rigid:WXZbxeJ/F+j8VN0lIPi48uiE+G4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BT25 uniprotkb:Q7Z4H7 intact:EBI-2558143|uniprotkb:B4DJA7|uniprotkb:Q86WF0|uniprotkb:Q49AC4|intact:EBI-2562724|uniprotkb:Q96FX3|uniprotkb:C9JBZ4|intact:EBI-11024560|ensembl:ENSP00000253669 intact:EBI-2558196|uniprotkb:Q05CG1|uniprotkb:Q14CB6|uniprotkb:Q2TA91|uniprotkb:Q8IZQ4|uniprotkb:Q9H998|uniprotkb:Q96FN0|uniprotkb:Q14CD9|uniprotkb:B3KPK4|uniprotkb:Q6IQ10|uniprotkb:Q9H950|uniprotkb:Q9NXT8|uniprotkb:Q9HCJ8|uniprotkb:Q6NZX5|uniprotkb:B4DX82|ensembl:ENSP00000369871 psi-mi:haus8_human(display_long)|uniprotkb:HICE1(gene name synonym)|uniprotkb:HEC1/NDC80-interacting centrosome-associated protein 1(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-48(gene name synonym)|uniprotkb:HAUS8(gene name)|psi-mi:HAUS8(display_short) psi-mi:haus6_human(display_long)|uniprotkb:HAUS6(gene name)|psi-mi:HAUS6(display_short)|uniprotkb:DGT6(gene name synonym)|uniprotkb:FAM29A(gene name synonym)|uniprotkb:KIAA1574(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479096|imex:IM-26985-401 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_219485.1|refseq:NP_001011699.1|dip:DIP-48834N|ensembl:ENSG00000131351(gene)|ensembl:ENST00000253669(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005880"(nuclear microtubule)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|mint:Q9BT25|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518 refseq:NP_060115.3|refseq:NP_001257819.1|dip:DIP-48830N|ensembl:ENSG00000147874(gene)|ensembl:ENST00000380502(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0034451"(centriolar satellite)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR026797|interpro:IPR028163|mint:Q7Z4H7|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518 - - comment:"author score: 229" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:q+J6qqmCxKWrUiWL50GtzEq9+AM9606 rogid:l5edu15aLS4hXrPg/lfQ2323G2o9606 rigid:WXZbxeJ/F+j8VN0lIPi48uiE+G4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BT25 uniprotkb:Q9H6D7 intact:EBI-2558143|uniprotkb:B4DJA7|uniprotkb:Q86WF0|uniprotkb:Q49AC4|intact:EBI-2562724|uniprotkb:Q96FX3|uniprotkb:C9JBZ4|intact:EBI-11024560|ensembl:ENSP00000253669 intact:EBI-2558168|uniprotkb:Q86U43|uniprotkb:Q86T16|uniprotkb:Q86T15|uniprotkb:Q9NX59|uniprotkb:B7WP17|uniprotkb:D3DS34|ensembl:ENSP00000206474|ensembl:ENSP00000441026 psi-mi:haus8_human(display_long)|uniprotkb:HICE1(gene name synonym)|uniprotkb:HEC1/NDC80-interacting centrosome-associated protein 1(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-48(gene name synonym)|uniprotkb:HAUS8(gene name)|psi-mi:HAUS8(display_short) psi-mi:haus4_human(display_long)|uniprotkb:HAUS4(gene name)|psi-mi:HAUS4(display_short)|uniprotkb:C14orf94(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479096|imex:IM-26985-401 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_219485.1|refseq:NP_001011699.1|dip:DIP-48834N|ensembl:ENSG00000131351(gene)|ensembl:ENST00000253669(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005880"(nuclear microtubule)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|mint:Q9BT25|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518 refseq:NP_001159741.1|refseq:NP_001159742.1|refseq:NP_060285.2|dip:DIP-48837N|ensembl:ENSG00000092036(gene)|ensembl:ENST00000206474(transcript)|ensembl:ENST00000541587(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR026214|interpro:IPR029327|mint:Q9H6D7|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518 - - comment:"author score: 230" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:q+J6qqmCxKWrUiWL50GtzEq9+AM9606 rogid:KWVJQqpFmFVFufH4Pq2Ecvp7SUA9606 rigid:WXZbxeJ/F+j8VN0lIPi48uiE+G4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BT25 uniprotkb:Q68CZ6 intact:EBI-2558143|uniprotkb:B4DJA7|uniprotkb:Q86WF0|uniprotkb:Q49AC4|intact:EBI-2562724|uniprotkb:Q96FX3|uniprotkb:C9JBZ4|intact:EBI-11024560|ensembl:ENSP00000253669 intact:EBI-2558217|uniprotkb:Q8TAZ5|uniprotkb:O43606|uniprotkb:Q9BTJ9|ensembl:ENSP00000243706|ensembl:ENSP00000500512|ensembl:ENSP00000392903|uniprotkb:B4DF64 psi-mi:haus8_human(display_long)|uniprotkb:HICE1(gene name synonym)|uniprotkb:HEC1/NDC80-interacting centrosome-associated protein 1(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-48(gene name synonym)|uniprotkb:HAUS8(gene name)|psi-mi:HAUS8(display_short) psi-mi:haus3_human(display_long)|uniprotkb:HAUS3(gene name)|psi-mi:HAUS3(display_short)|uniprotkb:C4orf15(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479096|imex:IM-26985-401 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_219485.1|refseq:NP_001011699.1|dip:DIP-48834N|ensembl:ENSG00000131351(gene)|ensembl:ENST00000253669(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005880"(nuclear microtubule)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|mint:Q9BT25|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518 refseq:NP_078787.2|ensembl:ENSG00000214367(gene)|ensembl:ENST00000243706(transcript)|ensembl:ENST00000443786(transcript)|ensembl:ENST00000672739(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR026206|interpro:IPR032733|mint:Q68CZ6|rcsb pdb:6PTB|rcsb pdb:6PTE|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001290072.1|dip:DIP-48832N - - comment:"author score: 244" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:q+J6qqmCxKWrUiWL50GtzEq9+AM9606 rogid:gmjepeLf/EVS51MLKnqrcuGniZA9606 rigid:WXZbxeJ/F+j8VN0lIPi48uiE+G4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q68CZ6 uniprotkb:Q9Y6H1 intact:EBI-2558217|uniprotkb:Q8TAZ5|uniprotkb:O43606|uniprotkb:Q9BTJ9|ensembl:ENSP00000243706|ensembl:ENSP00000500512|ensembl:ENSP00000392903|uniprotkb:B4DF64 intact:EBI-2321769|uniprotkb:Q498C3|uniprotkb:Q6NZ50|ensembl:ENSP00000378812 psi-mi:haus3_human(display_long)|uniprotkb:HAUS3(gene name)|psi-mi:HAUS3(display_short)|uniprotkb:C4orf15(gene name synonym) psi-mi:chch2_human(display_long)|uniprotkb:CHCHD2(gene name)|psi-mi:CHCHD2(display_short)|uniprotkb:C7orf17(gene name synonym)|uniprotkb:HCV NS2 trans-regulated protein(gene name synonym)|uniprotkb:Aging-associated gene 10 protein(gene name synonym)|uniprotkb:AAG10(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479072|imex:IM-26985-477 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078787.2|ensembl:ENSG00000214367(gene)|ensembl:ENST00000243706(transcript)|ensembl:ENST00000443786(transcript)|ensembl:ENST00000672739(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR026206|interpro:IPR032733|mint:Q68CZ6|rcsb pdb:6PTB|rcsb pdb:6PTE|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001290072.1|dip:DIP-48832N refseq:NP_057223.1|ensembl:ENSG00000106153(gene)|ensembl:ENST00000395422(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900037"(regulation of cellular response to hypoxia)|go:"GO:1905448"(positive regulation of mitochondrial ATP synthesis coupled electron transport)|interpro:IPR010625(CHCH)|mint:Q9Y6H1|reactome:R-HSA-1268020 - - comment:"author score: 48" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:gmjepeLf/EVS51MLKnqrcuGniZA9606 rogid:fdx3lE51+yZ1k3uwh8/LDKJC+CQ9606 rigid:wPneYauw4R15da7gQhZPQMr55sk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q68CZ6 uniprotkb:Q99871 intact:EBI-2558217|uniprotkb:Q8TAZ5|uniprotkb:O43606|uniprotkb:Q9BTJ9|ensembl:ENSP00000243706|ensembl:ENSP00000500512|ensembl:ENSP00000392903|uniprotkb:B4DF64 intact:EBI-395719|uniprotkb:Q96HS8|uniprotkb:Q9NP54|uniprotkb:D3DWT9|intact:EBI-2558192|uniprotkb:B4DUH6|uniprotkb:Q9UFH9|ensembl:ENSP00000359230 psi-mi:haus3_human(display_long)|uniprotkb:HAUS3(gene name)|psi-mi:HAUS3(display_short)|uniprotkb:C4orf15(gene name synonym) psi-mi:haus7_human(display_long)|uniprotkb:HAUS7(gene name)|psi-mi:HAUS7(display_short)|uniprotkb:26S proteasome-associated UCH37-interacting protein 1(gene name synonym)|uniprotkb:X-linked protein STS1769(gene name synonym)|uniprotkb:UIP1(gene name synonym)|uniprotkb:UCHL5IP(gene name synonym)|uniprotkb:UCHL5-interacting protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479072|imex:IM-26985-477 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078787.2|ensembl:ENSG00000214367(gene)|ensembl:ENST00000243706(transcript)|ensembl:ENST00000443786(transcript)|ensembl:ENST00000672739(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR026206|interpro:IPR032733|mint:Q68CZ6|rcsb pdb:6PTB|rcsb pdb:6PTE|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001290072.1|dip:DIP-48832N refseq:NP_059988.3|dip:DIP-32974N|ensembl:ENSG00000213397(gene)|ensembl:ENST00000370211(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0031996"(thioesterase binding)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR029711|mint:Q99871|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518 - - comment:"author score: 220" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:gmjepeLf/EVS51MLKnqrcuGniZA9606 rogid:nDQXUt43VCTD0vyH0M8OAsGJbEY9606 rigid:wPneYauw4R15da7gQhZPQMr55sk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q68CZ6 uniprotkb:O94927 intact:EBI-2558217|uniprotkb:Q8TAZ5|uniprotkb:O43606|uniprotkb:Q9BTJ9|ensembl:ENSP00000243706|ensembl:ENSP00000500512|ensembl:ENSP00000392903|uniprotkb:B4DF64 intact:EBI-2558224|uniprotkb:B2RXK1|uniprotkb:Q6P2P7|uniprotkb:Q96CT8|uniprotkb:Q7L3D5|ensembl:ENSP00000439056 psi-mi:haus3_human(display_long)|uniprotkb:HAUS3(gene name)|psi-mi:HAUS3(display_short)|uniprotkb:C4orf15(gene name synonym) psi-mi:haus5_human(display_long)|uniprotkb:HAUS5(gene name)|psi-mi:HAUS5(display_short)|uniprotkb:KIAA0841(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479072|imex:IM-26985-477 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078787.2|ensembl:ENSG00000214367(gene)|ensembl:ENST00000243706(transcript)|ensembl:ENST00000443786(transcript)|ensembl:ENST00000672739(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR026206|interpro:IPR032733|mint:Q68CZ6|rcsb pdb:6PTB|rcsb pdb:6PTE|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001290072.1|dip:DIP-48832N refseq:NP_056117.1|ensembl:ENSG00000249115(gene)|ensembl:ENST00000203166(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR026215|interpro:IPR029131|mint:O94927|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|dip:DIP-48831N - - comment:"author score: 262" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:gmjepeLf/EVS51MLKnqrcuGniZA9606 rogid:ChAZl+X89FxK08LHh2+lYDqQZn09606 rigid:wPneYauw4R15da7gQhZPQMr55sk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q68CZ6 uniprotkb:Q7Z4H7 intact:EBI-2558217|uniprotkb:Q8TAZ5|uniprotkb:O43606|uniprotkb:Q9BTJ9|ensembl:ENSP00000243706|ensembl:ENSP00000500512|ensembl:ENSP00000392903|uniprotkb:B4DF64 intact:EBI-2558196|uniprotkb:Q05CG1|uniprotkb:Q14CB6|uniprotkb:Q2TA91|uniprotkb:Q8IZQ4|uniprotkb:Q9H998|uniprotkb:Q96FN0|uniprotkb:Q14CD9|uniprotkb:B3KPK4|uniprotkb:Q6IQ10|uniprotkb:Q9H950|uniprotkb:Q9NXT8|uniprotkb:Q9HCJ8|uniprotkb:Q6NZX5|uniprotkb:B4DX82|ensembl:ENSP00000369871 psi-mi:haus3_human(display_long)|uniprotkb:HAUS3(gene name)|psi-mi:HAUS3(display_short)|uniprotkb:C4orf15(gene name synonym) psi-mi:haus6_human(display_long)|uniprotkb:HAUS6(gene name)|psi-mi:HAUS6(display_short)|uniprotkb:DGT6(gene name synonym)|uniprotkb:FAM29A(gene name synonym)|uniprotkb:KIAA1574(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479072|imex:IM-26985-477 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078787.2|ensembl:ENSG00000214367(gene)|ensembl:ENST00000243706(transcript)|ensembl:ENST00000443786(transcript)|ensembl:ENST00000672739(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR026206|interpro:IPR032733|mint:Q68CZ6|rcsb pdb:6PTB|rcsb pdb:6PTE|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001290072.1|dip:DIP-48832N refseq:NP_060115.3|refseq:NP_001257819.1|dip:DIP-48830N|ensembl:ENSG00000147874(gene)|ensembl:ENST00000380502(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0034451"(centriolar satellite)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR026797|interpro:IPR028163|mint:Q7Z4H7|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518 - - comment:"author score: 262" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:gmjepeLf/EVS51MLKnqrcuGniZA9606 rogid:l5edu15aLS4hXrPg/lfQ2323G2o9606 rigid:wPneYauw4R15da7gQhZPQMr55sk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q68CZ6 uniprotkb:Q96CS2 intact:EBI-2558217|uniprotkb:Q8TAZ5|uniprotkb:O43606|uniprotkb:Q9BTJ9|ensembl:ENSP00000243706|ensembl:ENSP00000500512|ensembl:ENSP00000392903|uniprotkb:B4DF64 intact:EBI-2514791|ensembl:ENSP00000282058|uniprotkb:Q8N837|uniprotkb:B2RDM7 psi-mi:haus3_human(display_long)|uniprotkb:HAUS3(gene name)|psi-mi:HAUS3(display_short)|uniprotkb:C4orf15(gene name synonym) psi-mi:haus1_human(display_long)|uniprotkb:HAUS1(gene name)|psi-mi:HAUS1(display_short)|uniprotkb:CCDC5(gene name synonym)|uniprotkb:HEIC(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 5(gene name synonym)|uniprotkb:Enhancer of invasion-cluster(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479072|imex:IM-26985-477 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078787.2|ensembl:ENSG00000214367(gene)|ensembl:ENST00000243706(transcript)|ensembl:ENST00000443786(transcript)|ensembl:ENST00000672739(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR026206|interpro:IPR032733|mint:Q68CZ6|rcsb pdb:6PTB|rcsb pdb:6PTE|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001290072.1|dip:DIP-48832N ensembl:ENSG00000152240(gene)|ensembl:ENST00000282058(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR026243|mint:Q96CS2|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_612452.1|dip:DIP-48835N - - comment:"author score: 264" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:gmjepeLf/EVS51MLKnqrcuGniZA9606 rogid:U+lgSilH3iBIHBktPv30KtUnDPg9606 rigid:wPneYauw4R15da7gQhZPQMr55sk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q68CZ6 uniprotkb:Q9H6D7 intact:EBI-2558217|uniprotkb:Q8TAZ5|uniprotkb:O43606|uniprotkb:Q9BTJ9|ensembl:ENSP00000243706|ensembl:ENSP00000500512|ensembl:ENSP00000392903|uniprotkb:B4DF64 intact:EBI-2558168|uniprotkb:Q86U43|uniprotkb:Q86T16|uniprotkb:Q86T15|uniprotkb:Q9NX59|uniprotkb:B7WP17|uniprotkb:D3DS34|ensembl:ENSP00000206474|ensembl:ENSP00000441026 psi-mi:haus3_human(display_long)|uniprotkb:HAUS3(gene name)|psi-mi:HAUS3(display_short)|uniprotkb:C4orf15(gene name synonym) psi-mi:haus4_human(display_long)|uniprotkb:HAUS4(gene name)|psi-mi:HAUS4(display_short)|uniprotkb:C14orf94(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479072|imex:IM-26985-477 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078787.2|ensembl:ENSG00000214367(gene)|ensembl:ENST00000243706(transcript)|ensembl:ENST00000443786(transcript)|ensembl:ENST00000672739(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR026206|interpro:IPR032733|mint:Q68CZ6|rcsb pdb:6PTB|rcsb pdb:6PTE|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001290072.1|dip:DIP-48832N refseq:NP_001159741.1|refseq:NP_001159742.1|refseq:NP_060285.2|dip:DIP-48837N|ensembl:ENSG00000092036(gene)|ensembl:ENST00000206474(transcript)|ensembl:ENST00000541587(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR026214|interpro:IPR029327|mint:Q9H6D7|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518 - - comment:"author score: 268" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:gmjepeLf/EVS51MLKnqrcuGniZA9606 rogid:KWVJQqpFmFVFufH4Pq2Ecvp7SUA9606 rigid:wPneYauw4R15da7gQhZPQMr55sk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVX0 uniprotkb:O75369 intact:EBI-720080|uniprotkb:Q9H9B3|uniprotkb:C9JH36|ensembl:ENSP00000260372 intact:EBI-352089|intact:EBI-1754974|uniprotkb:Q13706|uniprotkb:Q59EC2|uniprotkb:Q6MZJ1|uniprotkb:Q8WXS9|uniprotkb:Q8WXT0|uniprotkb:Q8WXT1|uniprotkb:Q8WXT2|uniprotkb:Q9NRB5|uniprotkb:B2ZZ84|uniprotkb:Q9NT26|uniprotkb:Q9UEV9|intact:EBI-1960054|uniprotkb:C9JKE6|uniprotkb:B2ZZ85|uniprotkb:C9JMC4|ensembl:ENSP00000295956|uniprotkb:B2ZZ83|uniprotkb:Q60FE7|uniprotkb:Q8WXT3 psi-mi:haus2_human(display_long)|uniprotkb:HAUS2(gene name)|psi-mi:HAUS2(display_short)|uniprotkb:C15orf25(gene name synonym)|uniprotkb:CEP27(gene name synonym)|uniprotkb:Centrosomal protein of 27 kDa(gene name synonym) psi-mi:flnb_human(display_long)|uniprotkb:FLNB(gene name)|psi-mi:FLNB(display_short)|uniprotkb:FLN1L(gene name synonym)|uniprotkb:FLN3(gene name synonym)|uniprotkb:TABP(gene name synonym)|uniprotkb:TAP(gene name synonym)|uniprotkb:Beta-filamin(gene name synonym)|uniprotkb:Actin-binding-like protein(gene name synonym)|uniprotkb:Thyroid autoantigen(gene name synonym)|uniprotkb:Truncated actin-binding protein(gene name synonym)|uniprotkb:ABP-280 homolog(gene name synonym)|uniprotkb:ABP-278(gene name synonym)|uniprotkb:Filamin-3(gene name synonym)|uniprotkb:Filamin homolog 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479027|imex:IM-26985-475 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001123919.1|refseq:NP_060567.1|ensembl:ENSG00000137814(gene)|ensembl:ENST00000260372(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR026242|interpro:IPR028346|mint:Q9NVX0|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001310560.1|refseq:NP_001310561.1|refseq:XP_016877885.1|refseq:XP_016877886.1|dip:DIP-48836N refseq:NP_001157791.1|refseq:NP_001448.2|go:"GO:0003334"(keratinocyte development)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045296"(cadherin binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR029874|interpro:IPR036872|interpro:IPR044801|mint:O75369|rcsb pdb:2DI8|rcsb pdb:2DI9|rcsb pdb:2DIA|rcsb pdb:2DIB|rcsb pdb:2DIC|rcsb pdb:2DJ4|rcsb pdb:2DLG|rcsb pdb:2DMB|rcsb pdb:2DMC|rcsb pdb:2E9I|rcsb pdb:2E9J|rcsb pdb:2EE6|rcsb pdb:2EE9|rcsb pdb:2EEA|rcsb pdb:2EEB|rcsb pdb:2EEC|rcsb pdb:2EED|rcsb pdb:2WA5|rcsb pdb:2WA6|rcsb pdb:2WA7|rcsb pdb:3FER|rcsb pdb:4B7L|rcsb pdb:5DCP|reactome:R-HSA-1169408|ensembl:ENSG00000136068(gene)|ensembl:ENST00000295956(transcript)|go:"GO:0001725"(stress fiber)|refseq:NP_001157789.1|refseq:NP_001157790.1 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:jkE5kg4JCVPKVwI2OuLe7H+mTV09606 rogid:lsf6C/Vg0io7UhUi1Kapgwp0p5E9606 rigid:6Wx312zKVUDv10R4eC1rFuKznGo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVX0 uniprotkb:Q14739 intact:EBI-720080|uniprotkb:Q9H9B3|uniprotkb:C9JH36|ensembl:ENSP00000260372 intact:EBI-1055147|uniprotkb:Q14740|uniprotkb:Q53GU7|uniprotkb:Q59FE6|uniprotkb:B2R5P3|ensembl:ENSP00000272163|ensembl:ENSP00000339883 psi-mi:haus2_human(display_long)|uniprotkb:HAUS2(gene name)|psi-mi:HAUS2(display_short)|uniprotkb:C15orf25(gene name synonym)|uniprotkb:CEP27(gene name synonym)|uniprotkb:Centrosomal protein of 27 kDa(gene name synonym) psi-mi:lbr_human(display_long)|uniprotkb:Integral nuclear envelope inner membrane protein(gene name synonym)|uniprotkb:LMN2R(gene name synonym)|uniprotkb:LBR(gene name)|psi-mi:LBR(display_short)|uniprotkb:"3-beta-hydroxysterol Delta (14)-reductase"(gene name synonym)|uniprotkb:C-14 sterol reductase(gene name synonym)|uniprotkb:Lamin-B receptor(gene name synonym)|uniprotkb:Sterol C14-reductase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479027|imex:IM-26985-475 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001123919.1|refseq:NP_060567.1|ensembl:ENSG00000137814(gene)|ensembl:ENST00000260372(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR026242|interpro:IPR028346|mint:Q9NVX0|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001310560.1|refseq:NP_001310561.1|refseq:XP_016877885.1|refseq:XP_016877886.1|dip:DIP-48836N refseq:NP_002287.2|refseq:NP_919424.1|refseq:XP_011542487.1|ensembl:ENSP00000272163|ensembl:ENSP00000339883|ensembl:ENSG00000143815(gene)|ensembl:ENST00000272163(transcript)|ensembl:ENST00000338179(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:2DIG|reactome:R-HSA-191273|reactome:R-HSA-2995383|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9022692|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016627"(oxidoreductase activity, acting on the CH-CH group of donors)|go:"GO:0030223"(neutrophil differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0050613"(delta14-sterol reductase activity)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0070402"(NADPH binding)|interpro:IPR001171(ERG4/ERG24 ergosterol biosynthesis protein)|interpro:IPR002999(Tudor)|interpro:IPR018083|interpro:IPR019023|mint:Q14739|dip:DIP-5987N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:jkE5kg4JCVPKVwI2OuLe7H+mTV09606 rogid:Ns5qFZb8njsTOK90hIddW2O+uQI9606 rigid:6Wx312zKVUDv10R4eC1rFuKznGo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVX0 uniprotkb:P68366 intact:EBI-720080|uniprotkb:Q9H9B3|uniprotkb:C9JH36|ensembl:ENSP00000260372 intact:EBI-351772|uniprotkb:A8MUB1|uniprotkb:P05215|ensembl:ENSP00000248437|uniprotkb:B3KNQ6|intact:EBI-11134566 psi-mi:haus2_human(display_long)|uniprotkb:HAUS2(gene name)|psi-mi:HAUS2(display_short)|uniprotkb:C15orf25(gene name synonym)|uniprotkb:CEP27(gene name synonym)|uniprotkb:Centrosomal protein of 27 kDa(gene name synonym) psi-mi:tba4a_human(display_long)|uniprotkb:TUBA4A(gene name)|psi-mi:TUBA4A(display_short)|uniprotkb:Tubulin alpha-1 chain(gene name synonym)|uniprotkb:Alpha-tubulin 1(gene name synonym)|uniprotkb:Testis-specific alpha-tubulin(gene name synonym)|uniprotkb:Tubulin H2-alpha(gene name synonym)|uniprotkb:TUBA1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479027|imex:IM-26985-475 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001123919.1|refseq:NP_060567.1|ensembl:ENSG00000137814(gene)|ensembl:ENST00000260372(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR026242|interpro:IPR028346|mint:Q9NVX0|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001310560.1|refseq:NP_001310561.1|refseq:XP_016877885.1|refseq:XP_016877886.1|dip:DIP-48836N refseq:NP_005991.1|ensembl:ENSG00000127824(gene)|ensembl:ENST00000248437(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019901"(protein kinase binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68366|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_001265481.1 - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:jkE5kg4JCVPKVwI2OuLe7H+mTV09606 rogid:6Oj9O8u7E6cLUJ1eT6y5slbk7uQ9606 rigid:6Wx312zKVUDv10R4eC1rFuKznGo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVX0 uniprotkb:P58557 intact:EBI-720080|uniprotkb:Q9H9B3|uniprotkb:C9JH36|ensembl:ENSP00000260372 intact:EBI-2114647|uniprotkb:D3DSN2|uniprotkb:B7WPA9|uniprotkb:B7WPF7|ensembl:ENSP00000329614|ensembl:ENSP00000380805|ensembl:ENSP00000380813 psi-mi:haus2_human(display_long)|uniprotkb:HAUS2(gene name)|psi-mi:HAUS2(display_short)|uniprotkb:C15orf25(gene name synonym)|uniprotkb:CEP27(gene name synonym)|uniprotkb:Centrosomal protein of 27 kDa(gene name synonym) psi-mi:ybey_human(display_long)|uniprotkb:YBEY(gene name)|psi-mi:YBEY(display_short)|uniprotkb:C21orf57(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479027|imex:IM-26985-475 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001123919.1|refseq:NP_060567.1|ensembl:ENSG00000137814(gene)|ensembl:ENST00000260372(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR026242|interpro:IPR028346|mint:Q9NVX0|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001310560.1|refseq:NP_001310561.1|refseq:XP_016877885.1|refseq:XP_016877886.1|dip:DIP-48836N refseq:NP_478061.1|refseq:NP_001300951.1|refseq:NP_001300952.1|refseq:NP_001300953.1|refseq:NP_001300954.1|refseq:NP_001300955.1|ensembl:ENSG00000182362(gene)|ensembl:ENST00000329319(transcript)|ensembl:ENST00000397691(transcript)|ensembl:ENST00000397701(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0006364"(rRNA processing)|go:"GO:0046872"(metal ion binding)|interpro:IPR002036(Protein of unknown function UPF0054)|interpro:IPR020549|interpro:IPR023091|mint:P58557 - - comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:jkE5kg4JCVPKVwI2OuLe7H+mTV09606 rogid:VOjeUF0iThxy1T2ywZGHB8ILorc9606 rigid:6Wx312zKVUDv10R4eC1rFuKznGo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVX0 uniprotkb:Q15154 intact:EBI-720080|uniprotkb:Q9H9B3|uniprotkb:C9JH36|ensembl:ENSP00000260372 intact:EBI-741421|uniprotkb:A6NNN6|uniprotkb:B4DYD5|uniprotkb:E7ETA6|uniprotkb:E7EV56|ensembl:ENSP00000327077|uniprotkb:Q58F13|uniprotkb:Q6P1K7|uniprotkb:Q8NB85|uniprotkb:Q9BWC1|uniprotkb:Q9H4A2|intact:EBI-2563316|intact:EBI-16421643|intact:EBI-10961691 psi-mi:haus2_human(display_long)|uniprotkb:HAUS2(gene name)|psi-mi:HAUS2(display_short)|uniprotkb:C15orf25(gene name synonym)|uniprotkb:CEP27(gene name synonym)|uniprotkb:Centrosomal protein of 27 kDa(gene name synonym) psi-mi:pcm1_human(display_long)|uniprotkb:PCM1(gene name)|psi-mi:PCM1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479027|imex:IM-26985-475 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001123919.1|refseq:NP_060567.1|ensembl:ENSG00000137814(gene)|ensembl:ENST00000260372(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR026242|interpro:IPR028346|mint:Q9NVX0|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001310560.1|refseq:NP_001310561.1|refseq:XP_016877885.1|refseq:XP_016877886.1|dip:DIP-48836N refseq:NP_006188.3|ensembl:ENSG00000078674(gene)|ensembl:ENST00000325083(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0001764"(neuron migration)|go:"GO:0035176"(social behavior)|go:"GO:0035735"(intraciliary transport involved in cilium assembly)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0060271"(cilium assembly)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR024138|interpro:IPR031446|mint:Q15154|rcsb pdb:6HYL|rcsb pdb:6HYM|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0016020"(membrane)|go:"GO:0022027"(interkinetic nuclear migration)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0034454"(microtubule anchoring at centrosome)|refseq:NP_001302437.1|dip:DIP-42189N - - comment:"author score: 32" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:jkE5kg4JCVPKVwI2OuLe7H+mTV09606 rogid:ktyZQ5ot9yYxZXSvWZjOxX/eVHA9606 rigid:6Wx312zKVUDv10R4eC1rFuKznGo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVX0 uniprotkb:Q9Y6H1 intact:EBI-720080|uniprotkb:Q9H9B3|uniprotkb:C9JH36|ensembl:ENSP00000260372 intact:EBI-2321769|uniprotkb:Q498C3|uniprotkb:Q6NZ50|ensembl:ENSP00000378812 psi-mi:haus2_human(display_long)|uniprotkb:HAUS2(gene name)|psi-mi:HAUS2(display_short)|uniprotkb:C15orf25(gene name synonym)|uniprotkb:CEP27(gene name synonym)|uniprotkb:Centrosomal protein of 27 kDa(gene name synonym) psi-mi:chch2_human(display_long)|uniprotkb:CHCHD2(gene name)|psi-mi:CHCHD2(display_short)|uniprotkb:C7orf17(gene name synonym)|uniprotkb:HCV NS2 trans-regulated protein(gene name synonym)|uniprotkb:Aging-associated gene 10 protein(gene name synonym)|uniprotkb:AAG10(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479027|imex:IM-26985-475 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001123919.1|refseq:NP_060567.1|ensembl:ENSG00000137814(gene)|ensembl:ENST00000260372(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR026242|interpro:IPR028346|mint:Q9NVX0|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001310560.1|refseq:NP_001310561.1|refseq:XP_016877885.1|refseq:XP_016877886.1|dip:DIP-48836N refseq:NP_057223.1|ensembl:ENSG00000106153(gene)|ensembl:ENST00000395422(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900037"(regulation of cellular response to hypoxia)|go:"GO:1905448"(positive regulation of mitochondrial ATP synthesis coupled electron transport)|interpro:IPR010625(CHCH)|mint:Q9Y6H1|reactome:R-HSA-1268020 - - comment:"author score: 101" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:jkE5kg4JCVPKVwI2OuLe7H+mTV09606 rogid:fdx3lE51+yZ1k3uwh8/LDKJC+CQ9606 rigid:6Wx312zKVUDv10R4eC1rFuKznGo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVX0 uniprotkb:Q99871 intact:EBI-720080|uniprotkb:Q9H9B3|uniprotkb:C9JH36|ensembl:ENSP00000260372 intact:EBI-395719|uniprotkb:Q96HS8|uniprotkb:Q9NP54|uniprotkb:D3DWT9|intact:EBI-2558192|uniprotkb:B4DUH6|uniprotkb:Q9UFH9|ensembl:ENSP00000359230 psi-mi:haus2_human(display_long)|uniprotkb:HAUS2(gene name)|psi-mi:HAUS2(display_short)|uniprotkb:C15orf25(gene name synonym)|uniprotkb:CEP27(gene name synonym)|uniprotkb:Centrosomal protein of 27 kDa(gene name synonym) psi-mi:haus7_human(display_long)|uniprotkb:HAUS7(gene name)|psi-mi:HAUS7(display_short)|uniprotkb:26S proteasome-associated UCH37-interacting protein 1(gene name synonym)|uniprotkb:X-linked protein STS1769(gene name synonym)|uniprotkb:UIP1(gene name synonym)|uniprotkb:UCHL5IP(gene name synonym)|uniprotkb:UCHL5-interacting protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479027|imex:IM-26985-475 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001123919.1|refseq:NP_060567.1|ensembl:ENSG00000137814(gene)|ensembl:ENST00000260372(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR026242|interpro:IPR028346|mint:Q9NVX0|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001310560.1|refseq:NP_001310561.1|refseq:XP_016877885.1|refseq:XP_016877886.1|dip:DIP-48836N refseq:NP_059988.3|dip:DIP-32974N|ensembl:ENSG00000213397(gene)|ensembl:ENST00000370211(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0031996"(thioesterase binding)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR029711|mint:Q99871|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518 - - comment:"author score: 345" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:jkE5kg4JCVPKVwI2OuLe7H+mTV09606 rogid:nDQXUt43VCTD0vyH0M8OAsGJbEY9606 rigid:6Wx312zKVUDv10R4eC1rFuKznGo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVX0 uniprotkb:Q9BT25 intact:EBI-720080|uniprotkb:Q9H9B3|uniprotkb:C9JH36|ensembl:ENSP00000260372 intact:EBI-2558143|uniprotkb:B4DJA7|uniprotkb:Q86WF0|uniprotkb:Q49AC4|intact:EBI-2562724|uniprotkb:Q96FX3|uniprotkb:C9JBZ4|intact:EBI-11024560|ensembl:ENSP00000253669 psi-mi:haus2_human(display_long)|uniprotkb:HAUS2(gene name)|psi-mi:HAUS2(display_short)|uniprotkb:C15orf25(gene name synonym)|uniprotkb:CEP27(gene name synonym)|uniprotkb:Centrosomal protein of 27 kDa(gene name synonym) psi-mi:haus8_human(display_long)|uniprotkb:HICE1(gene name synonym)|uniprotkb:HEC1/NDC80-interacting centrosome-associated protein 1(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-48(gene name synonym)|uniprotkb:HAUS8(gene name)|psi-mi:HAUS8(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479027|imex:IM-26985-475 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001123919.1|refseq:NP_060567.1|ensembl:ENSG00000137814(gene)|ensembl:ENST00000260372(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR026242|interpro:IPR028346|mint:Q9NVX0|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001310560.1|refseq:NP_001310561.1|refseq:XP_016877885.1|refseq:XP_016877886.1|dip:DIP-48836N refseq:NP_219485.1|refseq:NP_001011699.1|dip:DIP-48834N|ensembl:ENSG00000131351(gene)|ensembl:ENST00000253669(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005880"(nuclear microtubule)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|mint:Q9BT25|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518 - - comment:"author score: 373" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:jkE5kg4JCVPKVwI2OuLe7H+mTV09606 rogid:q+J6qqmCxKWrUiWL50GtzEq9+AM9606 rigid:6Wx312zKVUDv10R4eC1rFuKznGo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVX0 uniprotkb:Q96CS2 intact:EBI-720080|uniprotkb:Q9H9B3|uniprotkb:C9JH36|ensembl:ENSP00000260372 intact:EBI-2514791|ensembl:ENSP00000282058|uniprotkb:Q8N837|uniprotkb:B2RDM7 psi-mi:haus2_human(display_long)|uniprotkb:HAUS2(gene name)|psi-mi:HAUS2(display_short)|uniprotkb:C15orf25(gene name synonym)|uniprotkb:CEP27(gene name synonym)|uniprotkb:Centrosomal protein of 27 kDa(gene name synonym) psi-mi:haus1_human(display_long)|uniprotkb:HAUS1(gene name)|psi-mi:HAUS1(display_short)|uniprotkb:CCDC5(gene name synonym)|uniprotkb:HEIC(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 5(gene name synonym)|uniprotkb:Enhancer of invasion-cluster(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479027|imex:IM-26985-475 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001123919.1|refseq:NP_060567.1|ensembl:ENSG00000137814(gene)|ensembl:ENST00000260372(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR026242|interpro:IPR028346|mint:Q9NVX0|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001310560.1|refseq:NP_001310561.1|refseq:XP_016877885.1|refseq:XP_016877886.1|dip:DIP-48836N ensembl:ENSG00000152240(gene)|ensembl:ENST00000282058(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR026243|mint:Q96CS2|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_612452.1|dip:DIP-48835N - - comment:"author score: 410" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:jkE5kg4JCVPKVwI2OuLe7H+mTV09606 rogid:U+lgSilH3iBIHBktPv30KtUnDPg9606 rigid:6Wx312zKVUDv10R4eC1rFuKznGo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVX0 uniprotkb:O94927 intact:EBI-720080|uniprotkb:Q9H9B3|uniprotkb:C9JH36|ensembl:ENSP00000260372 intact:EBI-2558224|uniprotkb:B2RXK1|uniprotkb:Q6P2P7|uniprotkb:Q96CT8|uniprotkb:Q7L3D5|ensembl:ENSP00000439056 psi-mi:haus2_human(display_long)|uniprotkb:HAUS2(gene name)|psi-mi:HAUS2(display_short)|uniprotkb:C15orf25(gene name synonym)|uniprotkb:CEP27(gene name synonym)|uniprotkb:Centrosomal protein of 27 kDa(gene name synonym) psi-mi:haus5_human(display_long)|uniprotkb:HAUS5(gene name)|psi-mi:HAUS5(display_short)|uniprotkb:KIAA0841(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479027|imex:IM-26985-475 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001123919.1|refseq:NP_060567.1|ensembl:ENSG00000137814(gene)|ensembl:ENST00000260372(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR026242|interpro:IPR028346|mint:Q9NVX0|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001310560.1|refseq:NP_001310561.1|refseq:XP_016877885.1|refseq:XP_016877886.1|dip:DIP-48836N refseq:NP_056117.1|ensembl:ENSG00000249115(gene)|ensembl:ENST00000203166(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR026215|interpro:IPR029131|mint:O94927|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|dip:DIP-48831N - - comment:"author score: 428" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:jkE5kg4JCVPKVwI2OuLe7H+mTV09606 rogid:ChAZl+X89FxK08LHh2+lYDqQZn09606 rigid:6Wx312zKVUDv10R4eC1rFuKznGo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVX0 uniprotkb:Q7Z4H7 intact:EBI-720080|uniprotkb:Q9H9B3|uniprotkb:C9JH36|ensembl:ENSP00000260372 intact:EBI-2558196|uniprotkb:Q05CG1|uniprotkb:Q14CB6|uniprotkb:Q2TA91|uniprotkb:Q8IZQ4|uniprotkb:Q9H998|uniprotkb:Q96FN0|uniprotkb:Q14CD9|uniprotkb:B3KPK4|uniprotkb:Q6IQ10|uniprotkb:Q9H950|uniprotkb:Q9NXT8|uniprotkb:Q9HCJ8|uniprotkb:Q6NZX5|uniprotkb:B4DX82|ensembl:ENSP00000369871 psi-mi:haus2_human(display_long)|uniprotkb:HAUS2(gene name)|psi-mi:HAUS2(display_short)|uniprotkb:C15orf25(gene name synonym)|uniprotkb:CEP27(gene name synonym)|uniprotkb:Centrosomal protein of 27 kDa(gene name synonym) psi-mi:haus6_human(display_long)|uniprotkb:HAUS6(gene name)|psi-mi:HAUS6(display_short)|uniprotkb:DGT6(gene name synonym)|uniprotkb:FAM29A(gene name synonym)|uniprotkb:KIAA1574(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479027|imex:IM-26985-475 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001123919.1|refseq:NP_060567.1|ensembl:ENSG00000137814(gene)|ensembl:ENST00000260372(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR026242|interpro:IPR028346|mint:Q9NVX0|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001310560.1|refseq:NP_001310561.1|refseq:XP_016877885.1|refseq:XP_016877886.1|dip:DIP-48836N refseq:NP_060115.3|refseq:NP_001257819.1|dip:DIP-48830N|ensembl:ENSG00000147874(gene)|ensembl:ENST00000380502(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0034451"(centriolar satellite)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR026797|interpro:IPR028163|mint:Q7Z4H7|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518 - - comment:"author score: 444" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:jkE5kg4JCVPKVwI2OuLe7H+mTV09606 rogid:l5edu15aLS4hXrPg/lfQ2323G2o9606 rigid:6Wx312zKVUDv10R4eC1rFuKznGo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVX0 uniprotkb:Q9H6D7 intact:EBI-720080|uniprotkb:Q9H9B3|uniprotkb:C9JH36|ensembl:ENSP00000260372 intact:EBI-2558168|uniprotkb:Q86U43|uniprotkb:Q86T16|uniprotkb:Q86T15|uniprotkb:Q9NX59|uniprotkb:B7WP17|uniprotkb:D3DS34|ensembl:ENSP00000206474|ensembl:ENSP00000441026 psi-mi:haus2_human(display_long)|uniprotkb:HAUS2(gene name)|psi-mi:HAUS2(display_short)|uniprotkb:C15orf25(gene name synonym)|uniprotkb:CEP27(gene name synonym)|uniprotkb:Centrosomal protein of 27 kDa(gene name synonym) psi-mi:haus4_human(display_long)|uniprotkb:HAUS4(gene name)|psi-mi:HAUS4(display_short)|uniprotkb:C14orf94(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479027|imex:IM-26985-475 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001123919.1|refseq:NP_060567.1|ensembl:ENSG00000137814(gene)|ensembl:ENST00000260372(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR026242|interpro:IPR028346|mint:Q9NVX0|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001310560.1|refseq:NP_001310561.1|refseq:XP_016877885.1|refseq:XP_016877886.1|dip:DIP-48836N refseq:NP_001159741.1|refseq:NP_001159742.1|refseq:NP_060285.2|dip:DIP-48837N|ensembl:ENSG00000092036(gene)|ensembl:ENST00000206474(transcript)|ensembl:ENST00000541587(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR026214|interpro:IPR029327|mint:Q9H6D7|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518 - - comment:"author score: 445" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:jkE5kg4JCVPKVwI2OuLe7H+mTV09606 rogid:KWVJQqpFmFVFufH4Pq2Ecvp7SUA9606 rigid:6Wx312zKVUDv10R4eC1rFuKznGo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVX0 uniprotkb:Q68CZ6 intact:EBI-720080|uniprotkb:Q9H9B3|uniprotkb:C9JH36|ensembl:ENSP00000260372 intact:EBI-2558217|uniprotkb:Q8TAZ5|uniprotkb:O43606|uniprotkb:Q9BTJ9|ensembl:ENSP00000243706|ensembl:ENSP00000500512|ensembl:ENSP00000392903|uniprotkb:B4DF64 psi-mi:haus2_human(display_long)|uniprotkb:HAUS2(gene name)|psi-mi:HAUS2(display_short)|uniprotkb:C15orf25(gene name synonym)|uniprotkb:CEP27(gene name synonym)|uniprotkb:Centrosomal protein of 27 kDa(gene name synonym) psi-mi:haus3_human(display_long)|uniprotkb:HAUS3(gene name)|psi-mi:HAUS3(display_short)|uniprotkb:C4orf15(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479027|imex:IM-26985-475 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001123919.1|refseq:NP_060567.1|ensembl:ENSG00000137814(gene)|ensembl:ENST00000260372(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR026242|interpro:IPR028346|mint:Q9NVX0|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001310560.1|refseq:NP_001310561.1|refseq:XP_016877885.1|refseq:XP_016877886.1|dip:DIP-48836N refseq:NP_078787.2|ensembl:ENSG00000214367(gene)|ensembl:ENST00000243706(transcript)|ensembl:ENST00000443786(transcript)|ensembl:ENST00000672739(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR026206|interpro:IPR032733|mint:Q68CZ6|rcsb pdb:6PTB|rcsb pdb:6PTE|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001290072.1|dip:DIP-48832N - - comment:"author score: 453" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:jkE5kg4JCVPKVwI2OuLe7H+mTV09606 rogid:gmjepeLf/EVS51MLKnqrcuGniZA9606 rigid:6Wx312zKVUDv10R4eC1rFuKznGo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14929 uniprotkb:P68363 intact:EBI-2339359|uniprotkb:Q53SU4|uniprotkb:Q53QF0|uniprotkb:Q49A44|uniprotkb:Q6P594|uniprotkb:Q8WWB9|ensembl:ENSP00000264108 intact:EBI-487083|intact:EBI-1384226|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:Q27I68|ensembl:ENSP00000336799|uniprotkb:Q8WU19 psi-mi:hat1_human(display_long)|uniprotkb:HAT1(gene name)|psi-mi:HAT1(display_short)|uniprotkb:KAT1(gene name synonym)|uniprotkb:Histone acetyltransferase 1(gene name synonym) psi-mi:tba1b_human(display_long)|uniprotkb:TUBA1B(gene name)|psi-mi:TUBA1B(display_short)|uniprotkb:Tubulin alpha-ubiquitous chain(gene name synonym)|uniprotkb:Alpha-tubulin ubiquitous(gene name synonym)|uniprotkb:Tubulin K-alpha-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478994|imex:IM-26985-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003633.1|dip:DIP-52811N|ensembl:ENSG00000128708(gene)|ensembl:ENST00000264108(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006323"(DNA packaging)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006348"|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0007584"(response to nutrient)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR013523(Histone acetyltransferase HAT1, C-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017380(Histone acetyltransferase type B, catalytic subunit)|interpro:IPR019467|interpro:IPR037113|mint:O14929|rcsb pdb:2P0W|rcsb pdb:6VO5|reactome:R-HSA-3214847 refseq:NP_006073.2|ensembl:ENSG00000123416(gene)|ensembl:ENST00000336023(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-983189|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|go:"GO:0045121"(membrane raft)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68363|rcsb pdb:2E4H|rcsb pdb:5IJ0|rcsb pdb:5IJ9|rcsb pdb:5N5N|rcsb pdb:6E7B|rcsb pdb:6E7C|rcsb pdb:6I2I|go:"GO:0051301"(cell division)|rcsb pdb:6J4V|rcsb pdb:6J8O|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|rcsb pdb:6S8L|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9013407|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-2132295|reactome:R-HSA-9668328 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:80KgRaid3NeRfAUdTHMQ/r0VuGo9606 rogid:D4YpuLCXl/S+53qV7P7sF81aARY9606 rigid:4uk2Vfl2j5F5hEtIR/EPfSpzL+8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14929 uniprotkb:P01040 intact:EBI-2339359|uniprotkb:Q53SU4|uniprotkb:Q53QF0|uniprotkb:Q49A44|uniprotkb:Q6P594|uniprotkb:Q8WWB9|ensembl:ENSP00000264108 intact:EBI-724303|ensembl:ENSP00000264474|uniprotkb:Q6IB90 psi-mi:hat1_human(display_long)|uniprotkb:HAT1(gene name)|psi-mi:HAT1(display_short)|uniprotkb:KAT1(gene name synonym)|uniprotkb:Histone acetyltransferase 1(gene name synonym) psi-mi:cyta_human(display_long)|uniprotkb:Cystatin-AS(gene name synonym)|uniprotkb:Stefin-A(gene name synonym)|uniprotkb:CSTA(gene name)|psi-mi:CSTA(display_short)|uniprotkb:STF1(gene name synonym)|uniprotkb:STFA(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478994|imex:IM-26985-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003633.1|dip:DIP-52811N|ensembl:ENSG00000128708(gene)|ensembl:ENST00000264108(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006323"(DNA packaging)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006348"|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0007584"(response to nutrient)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR013523(Histone acetyltransferase HAT1, C-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017380(Histone acetyltransferase type B, catalytic subunit)|interpro:IPR019467|interpro:IPR037113|mint:O14929|rcsb pdb:2P0W|rcsb pdb:6VO5|reactome:R-HSA-3214847 refseq:NP_005204.1|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR001713(Proteinase inhibitor I25A, stefin A)|mint:P01040|rcsb pdb:1CYU|rcsb pdb:1CYV|rcsb pdb:1DVC|rcsb pdb:1DVD|rcsb pdb:1GD3|rcsb pdb:1GD4|rcsb pdb:1N9J|rcsb pdb:1NB3|rcsb pdb:1NB5|rcsb pdb:3K9M|rcsb pdb:3KFQ|interpro:IPR018073|rcsb pdb:3KSE|reactome:R-HSA-6809371|ensembl:ENSG00000121552(gene)|ensembl:ENST00000264474(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002020"(protease binding)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0045861"(negative regulation of proteolysis) - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:80KgRaid3NeRfAUdTHMQ/r0VuGo9606 rogid:SzbpyWUHlOtItIvffzuwhcqFsDI9606 rigid:4uk2Vfl2j5F5hEtIR/EPfSpzL+8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14929 uniprotkb:P25311 intact:EBI-2339359|uniprotkb:Q53SU4|uniprotkb:Q53QF0|uniprotkb:Q49A44|uniprotkb:Q6P594|uniprotkb:Q8WWB9|ensembl:ENSP00000264108 intact:EBI-2513837|ensembl:ENSP00000292401|uniprotkb:Q5XKQ4|uniprotkb:O60386|uniprotkb:Q8N4N0|uniprotkb:D6W5T8 psi-mi:hat1_human(display_long)|uniprotkb:HAT1(gene name)|psi-mi:HAT1(display_short)|uniprotkb:KAT1(gene name synonym)|uniprotkb:Histone acetyltransferase 1(gene name synonym) psi-mi:za2g_human(display_long)|uniprotkb:AZGP1(gene name)|psi-mi:AZGP1(display_short)|uniprotkb:ZAG(gene name synonym)|uniprotkb:ZNGP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478994|imex:IM-26985-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003633.1|dip:DIP-52811N|ensembl:ENSG00000128708(gene)|ensembl:ENST00000264108(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006323"(DNA packaging)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006348"|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0007584"(response to nutrient)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR013523(Histone acetyltransferase HAT1, C-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017380(Histone acetyltransferase type B, catalytic subunit)|interpro:IPR019467|interpro:IPR037113|mint:O14929|rcsb pdb:2P0W|rcsb pdb:6VO5|reactome:R-HSA-3214847 ensembl:ENSG00000160862(gene)|ensembl:ENST00000292401(transcript)|go:"GO:0001580"(detection of chemical stimulus involved in sensory perception of bitter taste)|go:"GO:0001895"(retina homeostasis)|go:"GO:0002476"(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0007155"(cell adhesion)|go:"GO:0008285"(negative regulation of cell population proliferation)|interpro:IPR036179|interpro:IPR037055|mint:P25311|rcsb pdb:1T7V|rcsb pdb:1T7W|rcsb pdb:1T7X|rcsb pdb:1T7Y|rcsb pdb:1T7Z|rcsb pdb:1T80|rcsb pdb:1ZAG|rcsb pdb:3ES6|rcsb pdb:6R2U|reactome:R-HSA-5223345|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|refseq:NP_001176.1 - - comment:"author score: 32" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:80KgRaid3NeRfAUdTHMQ/r0VuGo9606 rogid:3Fp6qALNiZRqsI8Kh2lTQ9IMYek9606 rigid:4uk2Vfl2j5F5hEtIR/EPfSpzL+8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14929 uniprotkb:P08118 intact:EBI-2339359|uniprotkb:Q53SU4|uniprotkb:Q53QF0|uniprotkb:Q49A44|uniprotkb:Q6P594|uniprotkb:Q8WWB9|ensembl:ENSP00000264108 intact:EBI-10195681|uniprotkb:Q13125|uniprotkb:P11999|uniprotkb:Q9UC59|uniprotkb:Q6IAY9|uniprotkb:B1API6|ensembl:ENSP00000463092 psi-mi:hat1_human(display_long)|uniprotkb:HAT1(gene name)|psi-mi:HAT1(display_short)|uniprotkb:KAT1(gene name synonym)|uniprotkb:Histone acetyltransferase 1(gene name synonym) psi-mi:msmb_human(display_long)|uniprotkb:MSMB(gene name)|psi-mi:MSMB(display_short)|uniprotkb:Immunoglobulin-binding factor(gene name synonym)|uniprotkb:PN44(gene name synonym)|uniprotkb:PRSP(gene name synonym)|uniprotkb:Prostate secreted seminal plasma protein(gene name synonym)|uniprotkb:Prostate secretory protein of 94 amino acids(gene name synonym)|uniprotkb:Seminal plasma beta-inhibin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478994|imex:IM-26985-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003633.1|dip:DIP-52811N|ensembl:ENSG00000128708(gene)|ensembl:ENST00000264108(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006323"(DNA packaging)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006348"|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0007584"(response to nutrient)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR013523(Histone acetyltransferase HAT1, C-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017380(Histone acetyltransferase type B, catalytic subunit)|interpro:IPR019467|interpro:IPR037113|mint:O14929|rcsb pdb:2P0W|rcsb pdb:6VO5|reactome:R-HSA-3214847 refseq:NP_002434.1|refseq:NP_619540.1|ensembl:ENSG00000263639(gene)|ensembl:ENST00000582163(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|interpro:IPR008735(Beta-microseminoprotein)|mint:P08118|rcsb pdb:2IZ3|rcsb pdb:3IX0 - - comment:"author score: 38" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:80KgRaid3NeRfAUdTHMQ/r0VuGo9606 rogid:YQg3JViDZTHFEtCwvOcPPqjUGUs9606 rigid:4uk2Vfl2j5F5hEtIR/EPfSpzL+8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14929 uniprotkb:Q96EE3 intact:EBI-2339359|uniprotkb:Q53SU4|uniprotkb:Q53QF0|uniprotkb:Q49A44|uniprotkb:Q6P594|uniprotkb:Q8WWB9|ensembl:ENSP00000264108 intact:EBI-922818|uniprotkb:Q8NFU6|uniprotkb:Q96MH3|uniprotkb:Q9C069|uniprotkb:A8K5B1|ensembl:ENSP00000262124 psi-mi:hat1_human(display_long)|uniprotkb:HAT1(gene name)|psi-mi:HAT1(display_short)|uniprotkb:KAT1(gene name synonym)|uniprotkb:Histone acetyltransferase 1(gene name synonym) psi-mi:seh1_human(display_long)|uniprotkb:Nup107-160 subcomplex subunit SEH1(gene name synonym)|uniprotkb:SEH1L(gene name)|psi-mi:SEH1L(display_short)|uniprotkb:SEC13L(gene name synonym)|uniprotkb:SEH1(gene name synonym)|uniprotkb:SEC13-like protein(gene name synonym)|uniprotkb:GATOR complex protein SEH1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478994|imex:IM-26985-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003633.1|dip:DIP-52811N|ensembl:ENSG00000128708(gene)|ensembl:ENST00000264108(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006323"(DNA packaging)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006348"|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0007584"(response to nutrient)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR013523(Histone acetyltransferase HAT1, C-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017380(Histone acetyltransferase type B, catalytic subunit)|interpro:IPR019467|interpro:IPR037113|mint:O14929|rcsb pdb:2P0W|rcsb pdb:6VO5|reactome:R-HSA-3214847 refseq:NP_001013455.1|refseq:NP_112493.2|ensembl:ENSP00000262124|ensembl:ENST00000399892|ensembl:ENSP00000382779|ensembl:ENSG00000085415(gene)|ensembl:ENST00000262124(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0015031"(protein transport)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034629"|go:"GO:0035859"(Seh1-associated complex)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0061700"(GATOR2 complex)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|interpro:IPR037363|interpro:IPR037597|mint:Q96EE3|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9639288|reactome:R-HSA-9648025 - - comment:"author score: 42" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:80KgRaid3NeRfAUdTHMQ/r0VuGo9606 rogid:I/aUTa3zTawK6QwtkrUkO8B51W49606 rigid:4uk2Vfl2j5F5hEtIR/EPfSpzL+8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14929 uniprotkb:P07288 intact:EBI-2339359|uniprotkb:Q53SU4|uniprotkb:Q53QF0|uniprotkb:Q49A44|uniprotkb:Q6P594|uniprotkb:Q8WWB9|ensembl:ENSP00000264108 intact:EBI-1220791|uniprotkb:G3XAE3|uniprotkb:Q15096|uniprotkb:Q16272|uniprotkb:Q86TG8|uniprotkb:C9JXH3|uniprotkb:G3V0H4|uniprotkb:Q8IXI4|ensembl:ENSP00000314151 psi-mi:hat1_human(display_long)|uniprotkb:HAT1(gene name)|psi-mi:HAT1(display_short)|uniprotkb:KAT1(gene name synonym)|uniprotkb:Histone acetyltransferase 1(gene name synonym) psi-mi:klk3_human(display_long)|uniprotkb:KLK3(gene name)|psi-mi:KLK3(display_short)|uniprotkb:APS(gene name synonym)|uniprotkb:Kallikrein-3(gene name synonym)|uniprotkb:Semenogelase(gene name synonym)|uniprotkb:Gamma-seminoprotein(gene name synonym)|uniprotkb:P-30 antigen(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478994|imex:IM-26985-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003633.1|dip:DIP-52811N|ensembl:ENSG00000128708(gene)|ensembl:ENST00000264108(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006323"(DNA packaging)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006348"|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0007584"(response to nutrient)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR013523(Histone acetyltransferase HAT1, C-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017380(Histone acetyltransferase type B, catalytic subunit)|interpro:IPR019467|interpro:IPR037113|mint:O14929|rcsb pdb:2P0W|rcsb pdb:6VO5|reactome:R-HSA-3214847 refseq:NP_001025218.1|refseq:NP_001025219.1|refseq:NP_001639.1|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|mint:P07288|rcsb pdb:1PFA|rcsb pdb:2PSA|rcsb pdb:2ZCH|rcsb pdb:2ZCK|rcsb pdb:2ZCL|rcsb pdb:3QUM|reactome:R-HSA-381426|reactome:R-HSA-5625886|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|ensembl:ENST00000326003(transcript)|go:"GO:0002803"(positive regulation of antibacterial peptide production)|go:"GO:0003073"(regulation of systemic arterial blood pressure)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0006508"(proteolysis)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016811"("hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides")|go:"GO:0030141"(secretory granule)|go:"GO:0031638"(zymogen activation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044267"(cellular protein metabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|ensembl:ENSG00000142515(gene) - - comment:"author score: 50" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:80KgRaid3NeRfAUdTHMQ/r0VuGo9606 rogid:zHGrnUnp/rNQg9HsI7RMalBX/BE9606 rigid:4uk2Vfl2j5F5hEtIR/EPfSpzL+8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14929 uniprotkb:Q02383 intact:EBI-2339359|uniprotkb:Q53SU4|uniprotkb:Q53QF0|uniprotkb:Q49A44|uniprotkb:Q6P594|uniprotkb:Q8WWB9|ensembl:ENSP00000264108 intact:EBI-2609565|uniprotkb:Q6X2M6|uniprotkb:Q53ZU2|uniprotkb:Q6X2M5|ensembl:ENSP00000361855 psi-mi:hat1_human(display_long)|uniprotkb:HAT1(gene name)|psi-mi:HAT1(display_short)|uniprotkb:KAT1(gene name synonym)|uniprotkb:Histone acetyltransferase 1(gene name synonym) psi-mi:semg2_human(display_long)|uniprotkb:SEMG2(gene name)|psi-mi:SEMG2(display_short)|uniprotkb:Semenogelin II(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478994|imex:IM-26985-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003633.1|dip:DIP-52811N|ensembl:ENSG00000128708(gene)|ensembl:ENST00000264108(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006323"(DNA packaging)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006348"|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0007584"(response to nutrient)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR013523(Histone acetyltransferase HAT1, C-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017380(Histone acetyltransferase type B, catalytic subunit)|interpro:IPR019467|interpro:IPR037113|mint:O14929|rcsb pdb:2P0W|rcsb pdb:6VO5|reactome:R-HSA-3214847 refseq:NP_002999.1|ensembl:ENSG00000124157(gene)|ensembl:ENST00000372769(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0048240"(sperm capacitation)|go:"GO:0050817"(coagulation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900005"(positive regulation of serine-type endopeptidase activity)|go:"GO:1901318"(negative regulation of flagellated sperm motility)|interpro:IPR008836(Semenogelin)|mint:Q02383 - - comment:"author score: 55" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:80KgRaid3NeRfAUdTHMQ/r0VuGo9606 rogid:Ftsnc12KC4KSzLwCnoLmImTNPaI9606 rigid:4uk2Vfl2j5F5hEtIR/EPfSpzL+8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14929 uniprotkb:P15309 intact:EBI-2339359|uniprotkb:Q53SU4|uniprotkb:Q53QF0|uniprotkb:Q49A44|uniprotkb:Q6P594|uniprotkb:Q8WWB9|ensembl:ENSP00000264108 intact:EBI-1222012|uniprotkb:Q96KY0|uniprotkb:Q96QK9|uniprotkb:Q96QM0|uniprotkb:D3DNC6|uniprotkb:Q5FBY0|ensembl:ENSP00000337471 psi-mi:hat1_human(display_long)|uniprotkb:HAT1(gene name)|psi-mi:HAT1(display_short)|uniprotkb:KAT1(gene name synonym)|uniprotkb:Histone acetyltransferase 1(gene name synonym) psi-mi:ppap_human(display_long)|uniprotkb:ACP3(gene name)|psi-mi:ACP3(display_short)|uniprotkb:5'-nucleotidase(gene name synonym)|uniprotkb:ACPP(gene name synonym)|uniprotkb:Acid phosphatase 3(gene name synonym)|uniprotkb:Ecto-5'-nucleotidase(gene name synonym)|uniprotkb:Thiamine monophosphatase(gene name synonym)|uniprotkb:Protein tyrosine phosphatase ACP3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478994|imex:IM-26985-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003633.1|dip:DIP-52811N|ensembl:ENSG00000128708(gene)|ensembl:ENST00000264108(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006323"(DNA packaging)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006348"|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0007584"(response to nutrient)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR013523(Histone acetyltransferase HAT1, C-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017380(Histone acetyltransferase type B, catalytic subunit)|interpro:IPR019467|interpro:IPR037113|mint:O14929|rcsb pdb:2P0W|rcsb pdb:6VO5|reactome:R-HSA-3214847 refseq:NP_001090.2|refseq:NP_001127666.1|refseq:NP_001278966.1|ensembl:ENSG00000014257(gene)|ensembl:ENST00000336375(transcript)|go:"GO:0003993"(acid phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006144"(purine nucleobase metabolic process)|go:"GO:0006772"(thiamine metabolic process)|go:"GO:0007040"(lysosome organization)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0012506"(vesicle membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0030175"(filopodium)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0042131"(thiamine phosphate phosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046085"(adenosine metabolic process)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0052642"(lysophosphatidic acid phosphatase activity)|go:"GO:0060168"(positive regulation of adenosine receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000560(Histidine acid phosphatase)|interpro:IPR029033|interpro:IPR033379|mint:P15309|rcsb pdb:1CVI|rcsb pdb:1ND5|rcsb pdb:1ND6|rcsb pdb:2HPA|rcsb pdb:2L3H|rcsb pdb:2L77|rcsb pdb:2L79|rcsb pdb:2MG0|rcsb pdb:3PPD|reactome:R-HSA-6798695 - - comment:"author score: 76" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:80KgRaid3NeRfAUdTHMQ/r0VuGo9606 rogid:FLbVR5/u8MLUphen4TZZaKOPY7U9606 rigid:4uk2Vfl2j5F5hEtIR/EPfSpzL+8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14929 uniprotkb:P04279 intact:EBI-2339359|uniprotkb:Q53SU4|uniprotkb:Q53QF0|uniprotkb:Q49A44|uniprotkb:Q6P594|uniprotkb:Q8WWB9|ensembl:ENSP00000264108 intact:EBI-953955|ensembl:ENSP00000361867|uniprotkb:Q6X4I9|uniprotkb:Q6Y809|uniprotkb:Q6Y822|uniprotkb:Q6Y823|uniprotkb:Q86U64|uniprotkb:Q96QM3|uniprotkb:Q53ZV0|uniprotkb:Q53ZV1|uniprotkb:Q53ZV2 psi-mi:hat1_human(display_long)|uniprotkb:HAT1(gene name)|psi-mi:HAT1(display_short)|uniprotkb:KAT1(gene name synonym)|uniprotkb:Histone acetyltransferase 1(gene name synonym) psi-mi:semg1_human(display_long)|uniprotkb:Semenogelin I(gene name synonym)|uniprotkb:SEMG1(gene name)|psi-mi:SEMG1(display_short)|uniprotkb:SEMG(gene name synonym)|uniprotkb:Cancer/testis antigen 103(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478994|imex:IM-26985-19 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003633.1|dip:DIP-52811N|ensembl:ENSG00000128708(gene)|ensembl:ENST00000264108(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006323"(DNA packaging)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006348"|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0007584"(response to nutrient)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR013523(Histone acetyltransferase HAT1, C-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017380(Histone acetyltransferase type B, catalytic subunit)|interpro:IPR019467|interpro:IPR037113|mint:O14929|rcsb pdb:2P0W|rcsb pdb:6VO5|reactome:R-HSA-3214847 ensembl:ENSG00000124233(gene)|ensembl:ENST00000372781(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0007320"(insemination)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0032991"(protein-containing complex)|go:"GO:0048240"(sperm capacitation)|go:"GO:0050817"(coagulation)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900005"(positive regulation of serine-type endopeptidase activity)|go:"GO:1901318"(negative regulation of flagellated sperm motility)|interpro:IPR008836(Semenogelin)|mint:P04279|reactome:R-HSA-6803157|reactome:R-HSA-977225|go:"GO:0090281"(negative regulation of calcium ion import)|refseq:NP_002998.1 - - comment:"author score: 115" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:80KgRaid3NeRfAUdTHMQ/r0VuGo9606 rogid:64nkdlFGdnz3KDB7rkGYOQ5l+uQ9606 rigid:4uk2Vfl2j5F5hEtIR/EPfSpzL+8 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16104 uniprotkb:Q8N108 intact:EBI-494830|uniprotkb:Q4ZGJ7|uniprotkb:Q6IAS5|ensembl:ENSP00000364310|ensembl:ENSP00000434024 intact:EBI-3504940|uniprotkb:Q5T104|uniprotkb:Q6AHY8|uniprotkb:Q86TB4|uniprotkb:Q8N156|uniprotkb:Q8N161|uniprotkb:Q8NC37|uniprotkb:Q8NES4|uniprotkb:Q8NES5|uniprotkb:Q8NES6|uniprotkb:Q8WWG2|uniprotkb:Q9HCG2|uniprotkb:Q08AE0|uniprotkb:Q5TAD5|uniprotkb:C9JFD4|uniprotkb:Q32NC4|uniprotkb:Q5TAD2|uniprotkb:Q5TAD4|ensembl:ENSP00000347514|uniprotkb:Q5TAD1 psi-mi:h2ax_human(display_long)|uniprotkb:H2AX(gene name)|psi-mi:H2AX(display_short)|uniprotkb:H2AFX(gene name synonym)|uniprotkb:Histone H2A.X(gene name synonym) psi-mi:mier1_human(display_long)|uniprotkb:MIER1(gene name)|psi-mi:MIER1(display_short)|uniprotkb:KIAA1610(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478961|imex:IM-26985-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000188486(gene)|ensembl:ENST00000375167(transcript)|ensembl:ENST00000530167(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000786"(nucleosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|refseq:NP_002096.1|dip:DIP-33604N|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|go:"GO:0005813"(centrosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090398"(cellular senescence)|go:"GO:0090734"(site of DNA damage)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P16104|rcsb pdb:1YDP|rcsb pdb:2AZM|rcsb pdb:2D31|rcsb pdb:2DYP|rcsb pdb:3SHV|rcsb pdb:3SQD|rcsb pdb:3SZM|rcsb pdb:3U3Z|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K refseq:NP_001071169.1|refseq:NP_001071170.2|refseq:NP_001071171.2|refseq:NP_001071172.1|refseq:NP_001139582.1|refseq:NP_001139584.1|refseq:NP_065999.2|refseq:NP_001265144.1|refseq:NP_001071168.2|refseq:NP_001139583.1|refseq:NP_001139585.1|ensembl:ENSG00000198160(gene)|ensembl:ENST00000355356(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0031937"(obsolete positive regulation of chromatin silencing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR031169|interpro:IPR040138|mint:Q8N108|refseq:XP_005271133.1|refseq:XP_016857413.1|refseq:XP_016857414.1|refseq:XP_016857415.1|refseq:XP_016857416.1|refseq:XP_016857417.1|refseq:XP_016857420.1 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:VQoEp3F8lEBTOj+PDDUzrJCQNZA9606 rogid:5WJANc4uv5fXG+0evX3ApSunJJE9606 rigid:DlK3++e4SP9tHrwMHVZPSkuTkjs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16104 uniprotkb:P55209 intact:EBI-494830|uniprotkb:Q4ZGJ7|uniprotkb:Q6IAS5|ensembl:ENSP00000364310|ensembl:ENSP00000434024 intact:EBI-356392|ensembl:ENSP00000376947|ensembl:ENSP00000477538|uniprotkb:B3KV44|uniprotkb:B3KNT8 psi-mi:h2ax_human(display_long)|uniprotkb:H2AX(gene name)|psi-mi:H2AX(display_short)|uniprotkb:H2AFX(gene name synonym)|uniprotkb:Histone H2A.X(gene name synonym) psi-mi:np1l1_human(display_long)|uniprotkb:NAP1L1(gene name)|psi-mi:NAP1L1(display_short)|uniprotkb:NRP(gene name synonym)|uniprotkb:NAP-1-related protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478961|imex:IM-26985-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000188486(gene)|ensembl:ENST00000375167(transcript)|ensembl:ENST00000530167(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000786"(nucleosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|refseq:NP_002096.1|dip:DIP-33604N|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|go:"GO:0005813"(centrosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090398"(cellular senescence)|go:"GO:0090734"(site of DNA damage)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P16104|rcsb pdb:1YDP|rcsb pdb:2AZM|rcsb pdb:2D31|rcsb pdb:2DYP|rcsb pdb:3SHV|rcsb pdb:3SQD|rcsb pdb:3SZM|rcsb pdb:3U3Z|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K ensembl:ENSG00000187109(gene)|ensembl:ENST00000393263(transcript)|ensembl:ENST00000618691(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0042393"(histone binding)|go:"GO:0042470"(melanosome)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:P55209|rcsb pdb:7BP5|refseq:NP_004528.1|refseq:NP_631946.1|refseq:NP_001294853.1|refseq:XP_011536695.1|refseq:NP_001317160.1|refseq:NP_001317161.1|refseq:XP_016874827.1 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:VQoEp3F8lEBTOj+PDDUzrJCQNZA9606 rogid:PtjzXGuxpQqrIEt5cbwzsbUoze89606 rigid:DlK3++e4SP9tHrwMHVZPSkuTkjs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16104 uniprotkb:Q3T8J9 intact:EBI-494830|uniprotkb:Q4ZGJ7|uniprotkb:Q6IAS5|ensembl:ENSP00000364310|ensembl:ENSP00000434024 intact:EBI-5659940|uniprotkb:Q5W0D5|uniprotkb:Q6P1Q6|uniprotkb:Q14C93|uniprotkb:Q6AWA6|uniprotkb:Q9HCG6|uniprotkb:Q9BQI1|uniprotkb:Q8IY79|uniprotkb:Q7Z3L3|uniprotkb:B7ZBL4|uniprotkb:Q5VYZ5|uniprotkb:Q3T8J8|ensembl:ENSP00000357315|ensembl:ENSP00000483100 psi-mi:h2ax_human(display_long)|uniprotkb:H2AX(gene name)|psi-mi:H2AX(display_short)|uniprotkb:H2AFX(gene name synonym)|uniprotkb:Histone H2A.X(gene name synonym) psi-mi:gon4l_human(display_long)|uniprotkb:GON-4 homolog(gene name synonym)|uniprotkb:GON4(gene name synonym)|uniprotkb:KIAA1606(gene name synonym)|uniprotkb:GON4L(gene name)|psi-mi:GON4L(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478961|imex:IM-26985-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000188486(gene)|ensembl:ENST00000375167(transcript)|ensembl:ENST00000530167(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000786"(nucleosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|refseq:NP_002096.1|dip:DIP-33604N|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|go:"GO:0005813"(centrosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090398"(cellular senescence)|go:"GO:0090734"(site of DNA damage)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P16104|rcsb pdb:1YDP|rcsb pdb:2AZM|rcsb pdb:2D31|rcsb pdb:2DYP|rcsb pdb:3SHV|rcsb pdb:3SQD|rcsb pdb:3SZM|rcsb pdb:3U3Z|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K refseq:NP_001269785.1|refseq:NP_001269787.1|refseq:NP_001269789.1|refseq:NP_001269790.1|refseq:NP_115668.4|refseq:XP_006711456.1|refseq:XP_006711457.1|ensembl:ENSG00000116580(gene)|ensembl:ENST00000368331(transcript)|ensembl:ENST00000615926(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016604"(nuclear body)|go:"GO:0030183"(B cell differentiation)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR003822(Paired amphipathic helix)|interpro:IPR009057(Homeodomain-like)|interpro:IPR033277|interpro:IPR036600|mint:Q3T8J9 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:VQoEp3F8lEBTOj+PDDUzrJCQNZA9606 rogid:nsGw7j7o2mxnXWd4kboGgCxSCDc9606 rigid:DlK3++e4SP9tHrwMHVZPSkuTkjs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16104 uniprotkb:Q9NP66 intact:EBI-494830|uniprotkb:Q4ZGJ7|uniprotkb:Q6IAS5|ensembl:ENSP00000364310|ensembl:ENSP00000434024 intact:EBI-740641|ensembl:ENSP00000336856|ensembl:ENSP00000371133|uniprotkb:A6NHY3|uniprotkb:Q53G31|uniprotkb:Q9NSF6|uniprotkb:D3DW78 psi-mi:h2ax_human(display_long)|uniprotkb:H2AX(gene name)|psi-mi:H2AX(display_short)|uniprotkb:H2AFX(gene name synonym)|uniprotkb:Histone H2A.X(gene name synonym) psi-mi:hm20a_human(display_long)|uniprotkb:HMG box-containing protein 20A(gene name synonym)|uniprotkb:HMG domain-containing protein HMGX1(gene name synonym)|uniprotkb:HMG20A(gene name)|psi-mi:HMG20A(display_short)|uniprotkb:HMGX1(gene name synonym)|uniprotkb:HMGXB1(gene name synonym)|uniprotkb:HMG domain-containing protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478961|imex:IM-26985-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000188486(gene)|ensembl:ENST00000375167(transcript)|ensembl:ENST00000530167(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000786"(nucleosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|refseq:NP_002096.1|dip:DIP-33604N|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|go:"GO:0005813"(centrosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090398"(cellular senescence)|go:"GO:0090734"(site of DNA damage)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P16104|rcsb pdb:1YDP|rcsb pdb:2AZM|rcsb pdb:2D31|rcsb pdb:2DYP|rcsb pdb:3SHV|rcsb pdb:3SQD|rcsb pdb:3SZM|rcsb pdb:3U3Z|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K refseq:NP_060670.1|ensembl:ENSG00000140382(gene)|ensembl:ENST00000336216(transcript)|ensembl:ENST00000381714(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|mint:Q9NP66|refseq:NP_001291433.1|refseq:NP_001291434.1|refseq:XP_011519460.1 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:VQoEp3F8lEBTOj+PDDUzrJCQNZA9606 rogid:LhilayeP+xv97pbYzIA8yMvwUbc9606 rigid:DlK3++e4SP9tHrwMHVZPSkuTkjs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16104 uniprotkb:O94880 intact:EBI-494830|uniprotkb:Q4ZGJ7|uniprotkb:Q6IAS5|ensembl:ENSP00000364310|ensembl:ENSP00000434024 intact:EBI-2680164|uniprotkb:B4DI82|uniprotkb:A7MCZ3|ensembl:ENSP00000385795 psi-mi:h2ax_human(display_long)|uniprotkb:H2AX(gene name)|psi-mi:H2AX(display_short)|uniprotkb:H2AFX(gene name synonym)|uniprotkb:Histone H2A.X(gene name synonym) psi-mi:phf14_human(display_long)|uniprotkb:KIAA0783(gene name synonym)|uniprotkb:PHF14(gene name)|psi-mi:PHF14(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478961|imex:IM-26985-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000188486(gene)|ensembl:ENST00000375167(transcript)|ensembl:ENST00000530167(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000786"(nucleosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|refseq:NP_002096.1|dip:DIP-33604N|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|go:"GO:0005813"(centrosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090398"(cellular senescence)|go:"GO:0090734"(site of DNA damage)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P16104|rcsb pdb:1YDP|rcsb pdb:2AZM|rcsb pdb:2D31|rcsb pdb:2DYP|rcsb pdb:3SHV|rcsb pdb:3SQD|rcsb pdb:3SZM|rcsb pdb:3U3Z|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K refseq:NP_055475.2|ensembl:ENSG00000106443(gene)|ensembl:ENST00000403050(transcript)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042393"(histone binding)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|mint:O94880 - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:VQoEp3F8lEBTOj+PDDUzrJCQNZA9606 rogid:5x6w7H9UP9mf4xk3lXYfAHaIo2Q9606 rigid:DlK3++e4SP9tHrwMHVZPSkuTkjs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16104 uniprotkb:Q9Y5B9 intact:EBI-494830|uniprotkb:Q4ZGJ7|uniprotkb:Q6IAS5|ensembl:ENSP00000364310|ensembl:ENSP00000434024 intact:EBI-1046849|uniprotkb:Q6GMT8|uniprotkb:Q6P2F1|uniprotkb:Q6PJM1|uniprotkb:Q9NRX0|ensembl:ENSP00000216297 psi-mi:h2ax_human(display_long)|uniprotkb:H2AX(gene name)|psi-mi:H2AX(display_short)|uniprotkb:H2AFX(gene name synonym)|uniprotkb:Histone H2A.X(gene name synonym) psi-mi:sp16h_human(display_long)|uniprotkb:Facilitates chromatin transcription complex subunit SPT16(gene name synonym)|uniprotkb:FACT 140 kDa subunit(gene name synonym)|uniprotkb:FACTp140(gene name synonym)|uniprotkb:Chromatin-specific transcription elongation factor 140 kDa subunit(gene name synonym)|uniprotkb:SUPT16H(gene name)|psi-mi:SUPT16H(display_short)|uniprotkb:FACT140(gene name synonym)|uniprotkb:FACTP140(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478961|imex:IM-26985-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000188486(gene)|ensembl:ENST00000375167(transcript)|ensembl:ENST00000530167(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000786"(nucleosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|refseq:NP_002096.1|dip:DIP-33604N|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|go:"GO:0005813"(centrosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090398"(cellular senescence)|go:"GO:0090734"(site of DNA damage)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P16104|rcsb pdb:1YDP|rcsb pdb:2AZM|rcsb pdb:2D31|rcsb pdb:2DYP|rcsb pdb:3SHV|rcsb pdb:3SQD|rcsb pdb:3SZM|rcsb pdb:3U3Z|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K ensembl:ENSG00000092201(gene)|ensembl:ENST00000216297(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034724"(DNA replication-independent chromatin organization)|go:"GO:0035101"(FACT complex)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR013953(FACT complex subunit Spt16p/Cdc68p)|interpro:IPR029148|interpro:IPR029149|interpro:IPR033825|interpro:IPR036005|interpro:IPR040258|mint:Q9Y5B9|rcsb pdb:4Z2M|rcsb pdb:4Z2N|rcsb pdb:5E5B|rcsb pdb:5UMT|rcsb pdb:5UMU|rcsb pdb:5XM2|rcsb pdb:6UPK|rcsb pdb:6UPL|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6804756|reactome:R-HSA-75955|refseq:NP_009123.1|dip:DIP-42757N - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:VQoEp3F8lEBTOj+PDDUzrJCQNZA9606 rogid:jLK5dOF3mEyI0UbZhcNgtdlG+WI9606 rigid:DlK3++e4SP9tHrwMHVZPSkuTkjs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16104 uniprotkb:P62805 intact:EBI-494830|uniprotkb:Q4ZGJ7|uniprotkb:Q6IAS5|ensembl:ENSP00000364310|ensembl:ENSP00000434024 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:h2ax_human(display_long)|uniprotkb:H2AX(gene name)|psi-mi:H2AX(display_short)|uniprotkb:H2AFX(gene name synonym)|uniprotkb:Histone H2A.X(gene name synonym) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478961|imex:IM-26985-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000188486(gene)|ensembl:ENST00000375167(transcript)|ensembl:ENST00000530167(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000786"(nucleosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|refseq:NP_002096.1|dip:DIP-33604N|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|go:"GO:0005813"(centrosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090398"(cellular senescence)|go:"GO:0090734"(site of DNA damage)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P16104|rcsb pdb:1YDP|rcsb pdb:2AZM|rcsb pdb:2D31|rcsb pdb:2DYP|rcsb pdb:3SHV|rcsb pdb:3SQD|rcsb pdb:3SZM|rcsb pdb:3U3Z|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - comment:"author score: 44" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:VQoEp3F8lEBTOj+PDDUzrJCQNZA9606 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 rigid:DlK3++e4SP9tHrwMHVZPSkuTkjs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16104 uniprotkb:O15355 intact:EBI-494830|uniprotkb:Q4ZGJ7|uniprotkb:Q6IAS5|ensembl:ENSP00000364310|ensembl:ENSP00000434024 intact:EBI-725702|ensembl:ENSP00000342778 psi-mi:h2ax_human(display_long)|uniprotkb:H2AX(gene name)|psi-mi:H2AX(display_short)|uniprotkb:H2AFX(gene name synonym)|uniprotkb:Histone H2A.X(gene name synonym) psi-mi:ppm1g_human(display_long)|uniprotkb:Protein phosphatase 2C isoform gamma(gene name synonym)|uniprotkb:Protein phosphatase magnesium-dependent 1 gamma(gene name synonym)|uniprotkb:Protein phosphatase 1C(gene name synonym)|uniprotkb:PPM1G(gene name)|psi-mi:PPM1G(display_short)|uniprotkb:PPM1C(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478961|imex:IM-26985-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000188486(gene)|ensembl:ENST00000375167(transcript)|ensembl:ENST00000530167(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000786"(nucleosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|refseq:NP_002096.1|dip:DIP-33604N|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|go:"GO:0005813"(centrosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090398"(cellular senescence)|go:"GO:0090734"(site of DNA damage)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P16104|rcsb pdb:1YDP|rcsb pdb:2AZM|rcsb pdb:2D31|rcsb pdb:2DYP|rcsb pdb:3SHV|rcsb pdb:3SQD|rcsb pdb:3SZM|rcsb pdb:3U3Z|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K refseq:NP_817092.1|ensembl:ENST00000344034(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|ensembl:ENSG00000115241(gene)|go:"GO:0016020"(membrane)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C, manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:O15355|dip:DIP-29404N - - comment:"author score: 48" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:VQoEp3F8lEBTOj+PDDUzrJCQNZA9606 rogid:j9ut2f7QHVyOtsLuYJ8e2XOP3HE9606 rigid:DlK3++e4SP9tHrwMHVZPSkuTkjs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16104 uniprotkb:P06899 intact:EBI-494830|uniprotkb:Q4ZGJ7|uniprotkb:Q6IAS5|ensembl:ENSP00000364310|ensembl:ENSP00000434024 intact:EBI-6150252|uniprotkb:B2R4J4|uniprotkb:O60816|ensembl:ENSP00000342886|ensembl:ENSP00000476136 psi-mi:h2ax_human(display_long)|uniprotkb:H2AX(gene name)|psi-mi:H2AX(display_short)|uniprotkb:H2AFX(gene name synonym)|uniprotkb:Histone H2A.X(gene name synonym) psi-mi:h2b1j_human(display_long)|uniprotkb:H2BC11(gene name)|psi-mi:H2BC11(display_short)|uniprotkb:H2BFR(gene name synonym)|uniprotkb:HIST1H2BJ(gene name synonym)|uniprotkb:Histone H2B.1(gene name synonym)|uniprotkb:Histone H2B.r(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25478961|imex:IM-26985-93 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000188486(gene)|ensembl:ENST00000375167(transcript)|ensembl:ENST00000530167(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000786"(nucleosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|refseq:NP_002096.1|dip:DIP-33604N|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|go:"GO:0005813"(centrosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090398"(cellular senescence)|go:"GO:0090734"(site of DNA damage)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P16104|rcsb pdb:1YDP|rcsb pdb:2AZM|rcsb pdb:2D31|rcsb pdb:2DYP|rcsb pdb:3SHV|rcsb pdb:3SQD|rcsb pdb:3SZM|rcsb pdb:3U3Z|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K refseq:NP_066402.2|dip:DIP-421N|ensembl:ENSG00000124635(gene)|ensembl:ENST00000339812(transcript)|ensembl:ENST00000607124(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P06899|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WAA|rcsb pdb:3WTP|rcsb pdb:4CAY|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5FUG|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5VEY|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6JXD|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6YOV|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7K5X|rcsb pdb:3WA9|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - comment:"author score: 62" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:VQoEp3F8lEBTOj+PDDUzrJCQNZA9606 rogid:74GQlSjGG1Ez6Uog74VXPLryKBc9606 rigid:DlK3++e4SP9tHrwMHVZPSkuTkjs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96EW2 uniprotkb:P20719 intact:EBI-720457|uniprotkb:Q6P476|uniprotkb:Q8N8J4|uniprotkb:Q8NHH6|uniprotkb:Q8WWF0|ensembl:ENSP00000302562 intact:EBI-8470697|uniprotkb:Q96CY6|intact:MINT-2801671|uniprotkb:O43367|uniprotkb:A4D179|ensembl:ENSP00000222726 psi-mi:hbap1_human(display_long)|uniprotkb:27 kDa heat shock protein-associated protein 1(gene name synonym)|uniprotkb:Protein associated with small stress protein 1(gene name synonym)|uniprotkb:HSPBAP1(gene name)|psi-mi:HSPBAP1(display_short)|uniprotkb:PASS1(gene name synonym) psi-mi:hxa5_human(display_long)|uniprotkb:HOXA5(gene name)|psi-mi:HOXA5(display_short)|uniprotkb:HOX1C(gene name synonym)|uniprotkb:Homeobox protein Hox-1C(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479462|imex:IM-26985-169 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078886.2|ensembl:ENSG00000169087(gene)|ensembl:ENST00000306103(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR013296("Protein Associated with Small Stress protein 1 (PASS1)")|interpro:IPR041667|mint:Q96EW2|refseq:NP_001307657.1|refseq:XP_005247819.1 refseq:NP_061975.2|ensembl:ENSG00000106004(gene)|ensembl:ENST00000222726(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003016"(respiratory system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016477"(cell migration)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030878"(thyroid gland development)|go:"GO:0033599"(regulation of mammary gland epithelial cell proliferation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045639"(positive regulation of myeloid cell differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060435"(bronchiole development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060480"(lung goblet cell differentiation)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060535"(trachea cartilage morphogenesis)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0060638"(mesenchymal-epithelial cell signaling)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060764"(cell-cell signaling involved in mammary gland development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|mint:P20719 - - comment:mint|comment:homomint|function:Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Also binds to its own promoter. Binds specifically to the motif 5'-CYYNATTA[TG]Y-3'|comment:"author score: 49" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5KvIFh1GwZSyAKD2EloRz2oweNk9606 rogid:1W+oOoovKja439tdjkg3QjmSB9Q9606 rigid:GKu7oKSq76UnT3dmib9NAAVv7XM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96EW2 uniprotkb:P01008 intact:EBI-720457|uniprotkb:Q6P476|uniprotkb:Q8N8J4|uniprotkb:Q8NHH6|uniprotkb:Q8WWF0|ensembl:ENSP00000302562 intact:EBI-1039832|uniprotkb:P78439|uniprotkb:P78447|uniprotkb:Q13815|uniprotkb:Q7KZ43|uniprotkb:B2R6P0|uniprotkb:Q5TC78|uniprotkb:Q7KZ97|uniprotkb:Q9UC78|ensembl:ENSP00000356671 psi-mi:hbap1_human(display_long)|uniprotkb:27 kDa heat shock protein-associated protein 1(gene name synonym)|uniprotkb:Protein associated with small stress protein 1(gene name synonym)|uniprotkb:HSPBAP1(gene name)|psi-mi:HSPBAP1(display_short)|uniprotkb:PASS1(gene name synonym) psi-mi:ant3_human(display_long)|uniprotkb:SERPINC1(gene name)|psi-mi:SERPINC1(display_short)|uniprotkb:AT3(gene name synonym)|uniprotkb:PRO0309(orf name)|uniprotkb:Serpin C1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479462|imex:IM-26985-169 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078886.2|ensembl:ENSG00000169087(gene)|ensembl:ENST00000306103(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR013296("Protein Associated with Small Stress protein 1 (PASS1)")|interpro:IPR041667|mint:Q96EW2|refseq:NP_001307657.1|refseq:XP_005247819.1 refseq:NP_000479.1|ensembl:ENSG00000117601(gene)|ensembl:ENST00000367698(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0002438"(acute inflammatory response to antigenic stimulus)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0007584"(response to nutrient)|go:"GO:0007595"(lactation)|go:"GO:0007596"(blood coagulation)|go:"GO:0008201"(heparin binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:2000266"(regulation of blood coagulation, intrinsic pathway)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR015555(Protease inhibitor I4, serpin, antithrombin-III)|interpro:IPR023795|interpro:IPR023796|interpro:IPR033829|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P01008|rcsb pdb:1ANT|rcsb pdb:1ATH|rcsb pdb:1AZX|rcsb pdb:1BR8|rcsb pdb:1DZG|rcsb pdb:1DZH|rcsb pdb:1E03|rcsb pdb:1E04|rcsb pdb:1E05|rcsb pdb:1JVQ|rcsb pdb:1LK6|rcsb pdb:1NQ9|rcsb pdb:1OYH|rcsb pdb:1R1L|rcsb pdb:1SR5|rcsb pdb:1T1F|rcsb pdb:1TB6|rcsb pdb:2ANT|rcsb pdb:2B4X|rcsb pdb:2B5T|rcsb pdb:2BEH|rcsb pdb:2GD4|rcsb pdb:2HIJ|rcsb pdb:2ZNH|rcsb pdb:3EVJ|rcsb pdb:3KCG|rcsb pdb:4EB1|reactome:R-HSA-140837|reactome:R-HSA-140875|reactome:R-HSA-381426|reactome:R-HSA-8957275|dip:DIP-38009N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5KvIFh1GwZSyAKD2EloRz2oweNk9606 rogid:XiPmXyU7CpPTgDR3dPnKeJEItJg9606 rigid:GKu7oKSq76UnT3dmib9NAAVv7XM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96EW2 uniprotkb:P82932 intact:EBI-720457|uniprotkb:Q6P476|uniprotkb:Q8N8J4|uniprotkb:Q8NHH6|uniprotkb:Q8WWF0|ensembl:ENSP00000302562 intact:EBI-716172|uniprotkb:Q96Q64|uniprotkb:Q9BSK8|uniprotkb:Q9BW89|uniprotkb:B2R573|ensembl:ENSP00000382250 psi-mi:hbap1_human(display_long)|uniprotkb:27 kDa heat shock protein-associated protein 1(gene name synonym)|uniprotkb:Protein associated with small stress protein 1(gene name synonym)|uniprotkb:HSPBAP1(gene name)|psi-mi:HSPBAP1(display_short)|uniprotkb:PASS1(gene name synonym) psi-mi:rt06_human(display_long)|uniprotkb:MRPS6(gene name)|psi-mi:MRPS6(display_short)|uniprotkb:C21orf101(gene name synonym)|uniprotkb:RPMS6(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein bS6m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479462|imex:IM-26985-169 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078886.2|ensembl:ENSG00000169087(gene)|ensembl:ENST00000306103(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR013296("Protein Associated with Small Stress protein 1 (PASS1)")|interpro:IPR041667|mint:Q96EW2|refseq:NP_001307657.1|refseq:XP_005247819.1 refseq:NP_115865.1|ensembl:ENSG00000243927(gene)|ensembl:ENST00000399312(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR000529(Ribosomal protein S6)|interpro:IPR014717(Translation elongation factor EF1B/ribosomal protein S6)|interpro:IPR035980|mint:P82932|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZSA|rcsb pdb:6ZS9|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5KvIFh1GwZSyAKD2EloRz2oweNk9606 rogid:mMPTr45GZxT1pj2RBZvvG6TrQmo9606 rigid:GKu7oKSq76UnT3dmib9NAAVv7XM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96EW2 uniprotkb:Q8N9T8 intact:EBI-720457|uniprotkb:Q6P476|uniprotkb:Q8N8J4|uniprotkb:Q8NHH6|uniprotkb:Q8WWF0|ensembl:ENSP00000302562 intact:EBI-724923|uniprotkb:Q2M1R5|uniprotkb:Q2M1R7|uniprotkb:Q7L5J7|uniprotkb:Q96G92|uniprotkb:Q9BU50|uniprotkb:Q9H6I1|uniprotkb:Q9H978|ensembl:ENSP00000320917 psi-mi:hbap1_human(display_long)|uniprotkb:27 kDa heat shock protein-associated protein 1(gene name synonym)|uniprotkb:Protein associated with small stress protein 1(gene name synonym)|uniprotkb:HSPBAP1(gene name)|psi-mi:HSPBAP1(display_short)|uniprotkb:PASS1(gene name synonym) psi-mi:kri1_human(display_long)|uniprotkb:KRI1(gene name)|psi-mi:KRI1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479462|imex:IM-26985-169 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078886.2|ensembl:ENSG00000169087(gene)|ensembl:ENST00000306103(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR013296("Protein Associated with Small Stress protein 1 (PASS1)")|interpro:IPR041667|mint:Q96EW2|refseq:NP_001307657.1|refseq:XP_005247819.1 refseq:NP_075384.3|ensembl:ENSG00000129347(gene)|ensembl:ENST00000312962(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|interpro:IPR018034|interpro:IPR024626|mint:Q8N9T8 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5KvIFh1GwZSyAKD2EloRz2oweNk9606 rogid:sIRmrP/c3tSmEAj1usRGN3R3Bh09606 rigid:GKu7oKSq76UnT3dmib9NAAVv7XM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96EW2 uniprotkb:P62273 intact:EBI-720457|uniprotkb:Q6P476|uniprotkb:Q8N8J4|uniprotkb:Q8NHH6|uniprotkb:Q8WWF0|ensembl:ENSP00000302562 intact:EBI-1054121|uniprotkb:P30054|uniprotkb:A8MZ73|ensembl:ENSP00000245458|ensembl:ENSP00000495033 psi-mi:hbap1_human(display_long)|uniprotkb:27 kDa heat shock protein-associated protein 1(gene name synonym)|uniprotkb:Protein associated with small stress protein 1(gene name synonym)|uniprotkb:HSPBAP1(gene name)|psi-mi:HSPBAP1(display_short)|uniprotkb:PASS1(gene name synonym) psi-mi:rs29_human(display_long)|uniprotkb:RPS29(gene name)|psi-mi:RPS29(display_short)|uniprotkb:Small ribosomal subunit protein uS14(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479462|imex:IM-26985-169 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078886.2|ensembl:ENSG00000169087(gene)|ensembl:ENST00000306103(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR013296("Protein Associated with Small Stress protein 1 (PASS1)")|interpro:IPR041667|mint:Q96EW2|refseq:NP_001307657.1|refseq:XP_005247819.1 refseq:NP_001023.1|refseq:NP_001025172.1|ensembl:ENSG00000213741(gene)|ensembl:ENST00000245458(transcript)|ensembl:ENST00000556230(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|interpro:IPR001209(Ribosomal protein S14)|interpro:IPR018271|interpro:IPR039744|interpro:IPR043140|mint:P62273|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5KvIFh1GwZSyAKD2EloRz2oweNk9606 rogid:vMgvFs6gwidbpv837yH2u0sSIAU9606 rigid:GKu7oKSq76UnT3dmib9NAAVv7XM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43593 uniprotkb:Q86VI3 intact:EBI-2880706|ensembl:ENSP00000370826|ensembl:ENSP00000505181|uniprotkb:Q9NPE1|uniprotkb:Q6GS30|uniprotkb:Q96H33 intact:EBI-1237354|uniprotkb:Q5T3H8|ensembl:ENSP00000354451 psi-mi:hair_human(display_long)|uniprotkb:"[histone H3]-dimethyl-L-lysine(9) demethylase hairless"(gene name synonym)|uniprotkb:HR(gene name)|psi-mi:HR(display_short) psi-mi:iqga3_human(display_long)|uniprotkb:IQGAP3(gene name)|psi-mi:IQGAP3(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479432|imex:IM-26985-167 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000168453(gene)|ensembl:ENST00000381418(transcript)|ensembl:ENST00000680789(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:O43593|refseq:NP_005135.2|refseq:NP_060881.2 refseq:NP_839943.2|ensembl:ENSP00000354451|ensembl:ENSG00000183856(gene)|ensembl:ENST00000361170(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0051015"(actin filament binding)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070856"(myosin VI light chain binding)|go:"GO:0071310"(cellular response to organic substance)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|mint:Q86VI3|rcsb pdb:3ISU|reactome:R-HSA-5626467|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|interpro:IPR036872 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:NTWtx2EKYeOrJuXwh8r6nutMnKQ9606 rogid:5lIYEC2lJihenWFio0Q+1W9EINI9606 rigid:T+kTSCOt2frxemQyBsbBhXYNW5Q false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43593 uniprotkb:P01040 intact:EBI-2880706|ensembl:ENSP00000370826|ensembl:ENSP00000505181|uniprotkb:Q9NPE1|uniprotkb:Q6GS30|uniprotkb:Q96H33 intact:EBI-724303|ensembl:ENSP00000264474|uniprotkb:Q6IB90 psi-mi:hair_human(display_long)|uniprotkb:"[histone H3]-dimethyl-L-lysine(9) demethylase hairless"(gene name synonym)|uniprotkb:HR(gene name)|psi-mi:HR(display_short) psi-mi:cyta_human(display_long)|uniprotkb:Cystatin-AS(gene name synonym)|uniprotkb:Stefin-A(gene name synonym)|uniprotkb:CSTA(gene name)|psi-mi:CSTA(display_short)|uniprotkb:STF1(gene name synonym)|uniprotkb:STFA(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479432|imex:IM-26985-167 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000168453(gene)|ensembl:ENST00000381418(transcript)|ensembl:ENST00000680789(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:O43593|refseq:NP_005135.2|refseq:NP_060881.2 refseq:NP_005204.1|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR001713(Proteinase inhibitor I25A, stefin A)|mint:P01040|rcsb pdb:1CYU|rcsb pdb:1CYV|rcsb pdb:1DVC|rcsb pdb:1DVD|rcsb pdb:1GD3|rcsb pdb:1GD4|rcsb pdb:1N9J|rcsb pdb:1NB3|rcsb pdb:1NB5|rcsb pdb:3K9M|rcsb pdb:3KFQ|interpro:IPR018073|rcsb pdb:3KSE|reactome:R-HSA-6809371|ensembl:ENSG00000121552(gene)|ensembl:ENST00000264474(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002020"(protease binding)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0045861"(negative regulation of proteolysis) - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:NTWtx2EKYeOrJuXwh8r6nutMnKQ9606 rogid:SzbpyWUHlOtItIvffzuwhcqFsDI9606 rigid:T+kTSCOt2frxemQyBsbBhXYNW5Q false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43593 uniprotkb:P0CG04 intact:EBI-2880706|ensembl:ENSP00000370826|ensembl:ENSP00000505181|uniprotkb:Q9NPE1|uniprotkb:Q6GS30|uniprotkb:Q96H33 intact:EBI-1221063|uniprotkb:P80423|uniprotkb:A0M8Q4|uniprotkb:P01842|uniprotkb:A0A075B6K8 psi-mi:hair_human(display_long)|uniprotkb:"[histone H3]-dimethyl-L-lysine(9) demethylase hairless"(gene name synonym)|uniprotkb:HR(gene name)|psi-mi:HR(display_short) psi-mi:iglc1_human(display_long)|uniprotkb:IGLC1(gene name)|psi-mi:IGLC1(display_short)|uniprotkb:Ig lambda chain C region MGC(gene name synonym)|uniprotkb:Ig lambda-1 chain C region(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479432|imex:IM-26985-167 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000168453(gene)|ensembl:ENST00000381418(transcript)|ensembl:ENST00000680789(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:O43593|refseq:NP_005135.2|refseq:NP_060881.2 interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|mint:P0CG04|interpro:IPR036179|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0034987"(immunoglobulin receptor binding)|go:"GO:0042571"(immunoglobulin complex, circulating)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|rcsb pdb:1ZVO|rcsb pdb:2FB4|rcsb pdb:2IG2|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|go:"GO:0045087"(innate immune response)|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664422|reactome:R-HSA-977606|reactome:R-HSA-983695|reactome:R-HSA-9664323 - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:NTWtx2EKYeOrJuXwh8r6nutMnKQ9606 rogid:OOdxBXPI2Jzf9HxurFZjk3/L1DM9606 rigid:T+kTSCOt2frxemQyBsbBhXYNW5Q false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43593 uniprotkb:P01008 intact:EBI-2880706|ensembl:ENSP00000370826|ensembl:ENSP00000505181|uniprotkb:Q9NPE1|uniprotkb:Q6GS30|uniprotkb:Q96H33 intact:EBI-1039832|uniprotkb:P78439|uniprotkb:P78447|uniprotkb:Q13815|uniprotkb:Q7KZ43|uniprotkb:B2R6P0|uniprotkb:Q5TC78|uniprotkb:Q7KZ97|uniprotkb:Q9UC78|ensembl:ENSP00000356671 psi-mi:hair_human(display_long)|uniprotkb:"[histone H3]-dimethyl-L-lysine(9) demethylase hairless"(gene name synonym)|uniprotkb:HR(gene name)|psi-mi:HR(display_short) psi-mi:ant3_human(display_long)|uniprotkb:SERPINC1(gene name)|psi-mi:SERPINC1(display_short)|uniprotkb:AT3(gene name synonym)|uniprotkb:PRO0309(orf name)|uniprotkb:Serpin C1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479432|imex:IM-26985-167 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000168453(gene)|ensembl:ENST00000381418(transcript)|ensembl:ENST00000680789(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:O43593|refseq:NP_005135.2|refseq:NP_060881.2 refseq:NP_000479.1|ensembl:ENSG00000117601(gene)|ensembl:ENST00000367698(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0002438"(acute inflammatory response to antigenic stimulus)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0007584"(response to nutrient)|go:"GO:0007595"(lactation)|go:"GO:0007596"(blood coagulation)|go:"GO:0008201"(heparin binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:2000266"(regulation of blood coagulation, intrinsic pathway)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR015555(Protease inhibitor I4, serpin, antithrombin-III)|interpro:IPR023795|interpro:IPR023796|interpro:IPR033829|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P01008|rcsb pdb:1ANT|rcsb pdb:1ATH|rcsb pdb:1AZX|rcsb pdb:1BR8|rcsb pdb:1DZG|rcsb pdb:1DZH|rcsb pdb:1E03|rcsb pdb:1E04|rcsb pdb:1E05|rcsb pdb:1JVQ|rcsb pdb:1LK6|rcsb pdb:1NQ9|rcsb pdb:1OYH|rcsb pdb:1R1L|rcsb pdb:1SR5|rcsb pdb:1T1F|rcsb pdb:1TB6|rcsb pdb:2ANT|rcsb pdb:2B4X|rcsb pdb:2B5T|rcsb pdb:2BEH|rcsb pdb:2GD4|rcsb pdb:2HIJ|rcsb pdb:2ZNH|rcsb pdb:3EVJ|rcsb pdb:3KCG|rcsb pdb:4EB1|reactome:R-HSA-140837|reactome:R-HSA-140875|reactome:R-HSA-381426|reactome:R-HSA-8957275|dip:DIP-38009N - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:NTWtx2EKYeOrJuXwh8r6nutMnKQ9606 rogid:XiPmXyU7CpPTgDR3dPnKeJEItJg9606 rigid:T+kTSCOt2frxemQyBsbBhXYNW5Q false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43593 uniprotkb:Q9BZK7 intact:EBI-2880706|ensembl:ENSP00000370826|ensembl:ENSP00000505181|uniprotkb:Q9NPE1|uniprotkb:Q6GS30|uniprotkb:Q96H33 intact:EBI-765729|uniprotkb:Q14DC3|uniprotkb:Q9H2I1|uniprotkb:Q9H9A1|uniprotkb:D3DNQ9|ensembl:ENSP00000263964|ensembl:ENSP00000387849|ensembl:ENSP00000405574|ensembl:ENSP00000413251|ensembl:ENSP00000501274 psi-mi:hair_human(display_long)|uniprotkb:"[histone H3]-dimethyl-L-lysine(9) demethylase hairless"(gene name synonym)|uniprotkb:HR(gene name)|psi-mi:HR(display_short) psi-mi:tbl1r_human(display_long)|uniprotkb:Transducin beta-like 1X-related protein 1(gene name synonym)|uniprotkb:Nuclear receptor corepressor/HDAC3 complex subunit TBLR1(gene name synonym)|uniprotkb:TBL1-related protein 1(gene name synonym)|uniprotkb:TBL1XR1(gene name)|psi-mi:TBL1XR1(display_short)|uniprotkb:IRA1(gene name synonym)|uniprotkb:TBLR1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479432|imex:IM-26985-167 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000168453(gene)|ensembl:ENST00000381418(transcript)|ensembl:ENST00000680789(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:O43593|refseq:NP_005135.2|refseq:NP_060881.2 refseq:NP_078941.2|refseq:XP_011511443.1|refseq:XP_011511444.1|refseq:XP_011511445.1|refseq:NP_001308123.1|refseq:NP_001308124.1|refseq:NP_001308122.1|refseq:XP_005247832.1|refseq:XP_006713809.1|refseq:XP_016862674.1|dip:DIP-34582N|ensembl:ENSG00000177565(gene)|ensembl:ENST00000422442(transcript)|ensembl:ENST00000352800(transcript)|ensembl:ENST00000430069(transcript)|ensembl:ENST00000457928(transcript)|ensembl:ENST00000673974(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0042393"(histone binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9BZK7|rcsb pdb:4LG9|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-2122947|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-381340|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9022537|reactome:R-HSA-9022692|reactome:R-HSA-9029569|reactome:R-HSA-9609690|reactome:R-HSA-9707564|reactome:R-HSA-9707616 - - comment:"author score: 35" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:NTWtx2EKYeOrJuXwh8r6nutMnKQ9606 rogid:Sr6jJZT7jdfR/ps1xK1ySq9/TuI9606 rigid:T+kTSCOt2frxemQyBsbBhXYNW5Q false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43593 uniprotkb:P30153 intact:EBI-2880706|ensembl:ENSP00000370826|ensembl:ENSP00000505181|uniprotkb:Q9NPE1|uniprotkb:Q6GS30|uniprotkb:Q96H33 intact:EBI-302388|uniprotkb:Q13773|uniprotkb:Q6ICQ3|uniprotkb:Q96DH3|ensembl:ENSP00000324804 psi-mi:hair_human(display_long)|uniprotkb:"[histone H3]-dimethyl-L-lysine(9) demethylase hairless"(gene name synonym)|uniprotkb:HR(gene name)|psi-mi:HR(display_short) psi-mi:2aaa_human(display_long)|uniprotkb:PPP2R1A(gene name)|psi-mi:PPP2R1A(display_short)|uniprotkb:PP2A subunit A isoform PR65-alpha(gene name synonym)|uniprotkb:PP2A subunit A isoform R1-alpha(gene name synonym)|uniprotkb:Medium tumor antigen-associated 61 kDa protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479432|imex:IM-26985-167 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000168453(gene)|ensembl:ENST00000381418(transcript)|ensembl:ENST00000680789(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:O43593|refseq:NP_005135.2|refseq:NP_060881.2 ensembl:ENSG00000105568(gene)|ensembl:ENST00000322088(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006672"(ceramide metabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008380"(RNA splicing)|go:"GO:0010033"(response to organic substance)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019932"(second-messenger-mediated signaling)|go:"GO:0030111"(regulation of Wnt signaling pathway)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0040008"(regulation of growth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990405"(protein antigen binding)|interpro:IPR000357(HEAT)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR031090|mint:P30153|rcsb pdb:1B3U|rcsb pdb:2IE3|rcsb pdb:2IE4|rcsb pdb:2NPP|rcsb pdb:2NYL|rcsb pdb:2NYM|rcsb pdb:2PKG|rcsb pdb:3C5W|rcsb pdb:3DW8|rcsb pdb:3K7V|rcsb pdb:3K7W|rcsb pdb:4I5L|rcsb pdb:4I5N|rcsb pdb:4LAC|rcsb pdb:5W0W|rcsb pdb:6IUR|rcsb pdb:6NTS|rcsb pdb:7CUN|rcsb pdb:7K36|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2995383|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5467348|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5675221|reactome:R-HSA-6804757|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-8854518|reactome:R-HSA-9634600|reactome:R-HSA-9648025|reactome:R-HSA-975957|refseq:NP_055040.2|dip:DIP-29394N - - comment:"author score: 37" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:NTWtx2EKYeOrJuXwh8r6nutMnKQ9606 rogid:73tR8yYYvViK8JdgIg18XWc3HRc9606 rigid:T+kTSCOt2frxemQyBsbBhXYNW5Q false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43593 uniprotkb:P63151 intact:EBI-2880706|ensembl:ENSP00000370826|ensembl:ENSP00000505181|uniprotkb:Q9NPE1|uniprotkb:Q6GS30|uniprotkb:Q96H33 intact:EBI-1048931|uniprotkb:P50409|uniprotkb:Q00007|uniprotkb:B2RBU8|intact:EBI-2556013|uniprotkb:B4E1T7|ensembl:ENSP00000370113 psi-mi:hair_human(display_long)|uniprotkb:"[histone H3]-dimethyl-L-lysine(9) demethylase hairless"(gene name synonym)|uniprotkb:HR(gene name)|psi-mi:HR(display_short) psi-mi:2aba_human(display_long)|uniprotkb:PPP2R2A(gene name)|psi-mi:PPP2R2A(display_short)|uniprotkb:PP2A subunit B isoform alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform B55-alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform PR55-alpha(gene name synonym)|uniprotkb:PP2A subunit B isoform R2-alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479432|imex:IM-26985-167 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000168453(gene)|ensembl:ENST00000381418(transcript)|ensembl:ENST00000680789(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:O43593|refseq:NP_005135.2|refseq:NP_060881.2 refseq:NP_001171062.1|refseq:NP_002708.1|ensembl:ENSG00000221914(gene)|ensembl:ENST00000380737(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0043278"(response to morphine)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000009(Protein phosphatase 2A, regulatory subunit PR55)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018067|interpro:IPR036322|mint:P63151|rcsb pdb:3DW8|reactome:R-HSA-2995383|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-975957|dip:DIP-29398N - - comment:"author score: 37" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:NTWtx2EKYeOrJuXwh8r6nutMnKQ9606 rogid:evS6klM2alZXtMthVsshKkrNgiA9606 rigid:T+kTSCOt2frxemQyBsbBhXYNW5Q false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43593 uniprotkb:P62714 intact:EBI-2880706|ensembl:ENSP00000370826|ensembl:ENSP00000505181|uniprotkb:Q9NPE1|uniprotkb:Q6GS30|uniprotkb:Q96H33 intact:EBI-1044367|ensembl:ENSP00000221138|uniprotkb:P11082|uniprotkb:D3DSV4|uniprotkb:Q6FHK5 psi-mi:hair_human(display_long)|uniprotkb:"[histone H3]-dimethyl-L-lysine(9) demethylase hairless"(gene name synonym)|uniprotkb:HR(gene name)|psi-mi:HR(display_short) psi-mi:pp2ab_human(display_long)|uniprotkb:PPP2CB(gene name)|psi-mi:PPP2CB(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479432|imex:IM-26985-167 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000168453(gene)|ensembl:ENST00000381418(transcript)|ensembl:ENST00000680789(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:O43593|refseq:NP_005135.2|refseq:NP_060881.2 refseq:NP_001009552.1|ensembl:ENSG00000104695(gene)|ensembl:ENST00000221138(transcript)|go:"GO:0000159"(protein phosphatase type 2A complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008637"(apoptotic mitochondrial changes)|go:"GO:0010288"(response to lead ion)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904528"(positive regulation of microtubule binding)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|go:"GO:0006470"(protein dephosphorylation)|interpro:IPR029052|mint:P62714|reactome:R-HSA-113501|reactome:R-HSA-1295596|reactome:R-HSA-141444|reactome:R-HSA-163685|reactome:R-HSA-163767|reactome:R-HSA-180024|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-198753|reactome:R-HSA-202670|reactome:R-HSA-2465910|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-389513|reactome:R-HSA-432142|reactome:R-HSA-4641262|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5467337|reactome:R-HSA-5467340|reactome:R-HSA-5675221|reactome:R-HSA-5467348|reactome:R-HSA-5663220|reactome:R-HSA-6804757|reactome:R-HSA-5673000|reactome:R-HSA-6811558|reactome:R-HSA-68877|reactome:R-HSA-69231|reactome:R-HSA-69273|reactome:R-HSA-9634600|reactome:R-HSA-9648025|dip:DIP-42325N - - comment:"author score: 50" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:NTWtx2EKYeOrJuXwh8r6nutMnKQ9606 rogid:ZWmB6it7rr0BS5sy38IxZ9QdR7U9606 rigid:T+kTSCOt2frxemQyBsbBhXYNW5Q false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P22492 uniprotkb:Q9NVS2 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 intact:EBI-7825353|ensembl:ENSP00000361206|intact:MINT-3075179|uniprotkb:Q5QPA4|uniprotkb:A6XND3 psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:rt18a_human(display_long)|uniprotkb:39S ribosomal protein S18-3, mitochondrial(gene name synonym)|uniprotkb:MRPS18A(gene name)|psi-mi:MRPS18A(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein bS18a(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein mL66(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479342|imex:IM-26985-247 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492 ensembl:ENSG00000096080(gene)|ensembl:ENST00000372133(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0032543"(mitochondrial translation)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR001648(Ribosomal protein S18)|interpro:IPR036870|mint:Q9NVS2|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5389840|reactome:R-HSA-5419276|reactome:R-HSA-5368286|refseq:NP_001180272.1|refseq:NP_060605.1|refseq:XP_006715197.1 - - comment:mint|comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 rogid:Qv26CehXGHVNy1T9ZFZGRLY65e89606 rigid:Z2UMy1yH+GoQwgACJ+BNsyjjR+M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P22492 uniprotkb:Q9P0M9 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 intact:EBI-5325236|ensembl:ENSP00000225969|uniprotkb:B2RE14 psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:rm27_human(display_long)|uniprotkb:Mitochondrial large ribosomal subunit protein bL27m(gene name synonym)|uniprotkb:HSPC250(orf name)|uniprotkb:MRPL27(gene name)|psi-mi:MRPL27(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479342|imex:IM-26985-247 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492 mint:Q9P0M9|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|ensembl:ENSG00000108826(gene)|ensembl:ENST00000225969(transcript)|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|rcsb pdb:6ZS9|rcsb pdb:6ZSA|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|rcsb pdb:6ZSB|interpro:IPR001684(Ribosomal protein L27)|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:NP_057588.1 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 rogid:Tb7r8GeSkNdNN6aY2mvmTR4MFmc9606 rigid:Z2UMy1yH+GoQwgACJ+BNsyjjR+M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P22492 uniprotkb:Q13595 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 intact:EBI-2685506|uniprotkb:B4DUA9|uniprotkb:B4DQI6|uniprotkb:E9PD75|ensembl:ENSP00000297071 psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:tra2a_human(display_long)|uniprotkb:Transformer-2 protein homolog A(gene name synonym)|uniprotkb:TRA2A(gene name)|psi-mi:TRA2A(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479342|imex:IM-26985-247 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492 refseq:NP_001269686.1|refseq:NP_001269687.1|refseq:NP_001269688.1|refseq:XP_005249782.1|refseq:NP_037425.1|refseq:XP_016867578.1|refseq:XP_016867579.1|ensembl:ENSG00000164548(gene)|ensembl:ENST00000297071(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:Q13595 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 rogid:JvcdzipB7mCy8eV3z8TaVjucLLM9606 rigid:Z2UMy1yH+GoQwgACJ+BNsyjjR+M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P22492 uniprotkb:P09001 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 intact:EBI-5325418|ensembl:ENSP00000264995|uniprotkb:Q6IBT2 psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:rm03_human(display_long)|uniprotkb:Mitochondrial large ribosomal subunit protein uL3m(gene name synonym)|uniprotkb:MRPL3(gene name)|psi-mi:MRPL3(display_short)|uniprotkb:MRL3(gene name synonym)|uniprotkb:RPML3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479342|imex:IM-26985-247 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492 ensembl:ENSG00000114686(gene)|ensembl:ENST00000264995(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|interpro:IPR000597(Ribosomal protein L3)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR019926|mint:P09001|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|interpro:IPR019927|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:7OF7|refseq:NP_009139.1 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 rogid:JsDyyXQz9ZMCkRtp5TuL0PGYCjw9606 rigid:Z2UMy1yH+GoQwgACJ+BNsyjjR+M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P22492 uniprotkb:Q01105 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479342|imex:IM-26985-247 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492 refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rigid:Z2UMy1yH+GoQwgACJ+BNsyjjR+M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P22492 uniprotkb:P62699 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 intact:EBI-11721624|uniprotkb:D6W568|uniprotkb:Q65Z97|uniprotkb:Q8R174|uniprotkb:Q9D6M1|uniprotkb:Q9UMX7|uniprotkb:Q9Y3C9|ensembl:ENSP00000261353|ensembl:ENSP00000368834|ensembl:ENSP00000368835|ensembl:ENSP00000383974|ensembl:ENSP00000385278 psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:ypel5_human(display_long)|uniprotkb:YPEL5(gene name)|psi-mi:YPEL5(display_short)|uniprotkb:CGI-127(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479342|imex:IM-26985-247 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492 refseq:NP_001120871.1|refseq:NP_001120872.1|refseq:NP_001120873.1|refseq:NP_057145.1|ensembl:ENSG00000119801(gene)|ensembl:ENST00000261353(transcript)|ensembl:ENST00000379519(transcript)|ensembl:ENST00000379520(transcript)|ensembl:ENST00000402003(transcript)|ensembl:ENST00000402708(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0008283"(cell population proliferation)|go:"GO:0030496"(midbody)|go:"GO:0046872"(metal ion binding)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004910(Yippee-like protein)|interpro:IPR034751|interpro:IPR039058|mint:P62699|reactome:R-HSA-6798695|refseq:XP_016859807.1|refseq:XP_016859808.1|refseq:XP_016859809.1|refseq:XP_016859810.1|refseq:XP_016859811.1 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 rogid:ZpDZwTkWSDPONRLnApZ8fKl/NHk9606 rigid:Z2UMy1yH+GoQwgACJ+BNsyjjR+M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P22492 uniprotkb:P46060 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 intact:EBI-396091|uniprotkb:Q96JJ2|ensembl:ENSP00000401470|ensembl:ENSP00000348577|ensembl:ENSP00000385866 psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:ragp1_human(display_long)|uniprotkb:RANGAP1(gene name)|psi-mi:RANGAP1(display_short)|uniprotkb:KIAA1835(gene name synonym)|uniprotkb:SD(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479342|imex:IM-26985-247 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492 refseq:NP_002874.1|ensembl:ENST00000356244(transcript)|ensembl:ENST00000405486(transcript)|ensembl:ENST00000455915(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0016235"(aggresome)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|refseq:XP_011528596.1|refseq:XP_011528597.1|refseq:NP_001304859.1|go:"GO:0031965"(nuclear membrane)|interpro:IPR009109(Ran-GTPase activating protein 1, C-terminal)|interpro:IPR032675|interpro:IPR036720|mint:P46060|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2IO2|rcsb pdb:2IO3|rcsb pdb:2IY0|rcsb pdb:3UIN|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:5D2M|reactome:R-HSA-141444|reactome:R-HSA-165054|reactome:R-HSA-2467813|interpro:IPR001611(Leucine-rich repeat)|reactome:R-HSA-2500257|reactome:R-HSA-3108232|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0045296"(cadherin binding)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048678"(response to axon injury)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1904117"(cellular response to vasopressin)|go:"GO:1990723"(cytoplasmic periphery of the nuclear pore complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|ensembl:ENSG00000100401(gene)|refseq:XP_006724352.1|reactome:R-HSA-4615885|refseq:NP_001265580.1|reactome:R-HSA-68877|reactome:R-HSA-9615933|reactome:R-HSA-9648025|reactome:R-HSA-5663220|refseq:XP_016884382.1|refseq:XP_016884383.1|refseq:XP_016884384.1|refseq:XP_016884385.1|refseq:XP_016884386.1|dip:DIP-29079N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 rogid:pUpd+7p5CeAKaRGLo/bXTeiwjiM9606 rigid:Z2UMy1yH+GoQwgACJ+BNsyjjR+M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P22492 uniprotkb:O75494 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 intact:EBI-353655|uniprotkb:Q5JRI3|uniprotkb:Q5JRI4|uniprotkb:A6NFM6|uniprotkb:A6NI42|uniprotkb:A6NIU7|uniprotkb:Q5JRH9|uniprotkb:Q5JRI2|uniprotkb:O60572|uniprotkb:Q96G09|uniprotkb:Q96P17|uniprotkb:Q5JRI0|intact:EBI-11103259|ensembl:ENSP00000420195|uniprotkb:B4DJP9 psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:srs10_human(display_long)|uniprotkb:FUSIP1(gene name synonym)|uniprotkb:TASR(gene name synonym)|uniprotkb:FUS-interacting serine-arginine-rich protein 1(gene name synonym)|uniprotkb:FUSIP2(gene name synonym)|uniprotkb:TLS-associated protein with Ser-Arg repeats(gene name synonym)|uniprotkb:TLS-associated serine-arginine protein(gene name synonym)|uniprotkb:40 kDa SR-repressor protein(gene name synonym)|uniprotkb:SRSF10(gene name)|psi-mi:SRSF10(display_short)|uniprotkb:Splicing factor SRp38(gene name synonym)|uniprotkb:SFRS13A(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 13A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479342|imex:IM-26985-247 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492 refseq:NP_001177936.1|refseq:NP_001177934.1|refseq:NP_001177935.1|refseq:NP_006616.1|refseq:NP_473357.1|ensembl:ENSG00000188529(gene)|ensembl:ENST00000492112(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0016482"(cytosolic transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0050733"(RS domain binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034476|interpro:IPR035979|mint:O75494|reactome:R-HSA-72163|refseq:NP_001177938.1 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 rogid:abrRZLYWl3wlG2rHzVZMgej5EWk9606 rigid:Z2UMy1yH+GoQwgACJ+BNsyjjR+M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P22492 uniprotkb:Q9NYK5 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 intact:EBI-2513042|ensembl:ENSP00000284967|uniprotkb:Q9BZV6|uniprotkb:Q32Q74|uniprotkb:Q9BSQ7|uniprotkb:Q5QTR3|uniprotkb:Q96Q65|uniprotkb:Q9NX44|uniprotkb:C9JYA5 psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:rm39_human(display_long)|uniprotkb:MRPL39(gene name)|psi-mi:MRPL39(display_short)|uniprotkb:C21orf92(gene name synonym)|uniprotkb:MRPL5(gene name synonym)|uniprotkb:RPML5(gene name synonym)|uniprotkb:39S ribosomal protein L5, mitochondrial(gene name synonym)|uniprotkb:MSTP003(orf name)|uniprotkb:PRED22(orf name)|uniprotkb:Mitochondrial large ribosomal subunit protein mL39(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479342|imex:IM-26985-247 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492 ensembl:ENSG00000154719(gene)|ensembl:ENST00000352957(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|interpro:IPR004095(TGS)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR012676(TGS-like)|interpro:IPR018163|mint:Q9NYK5|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:6NU3|refseq:NP_059142.2|refseq:NP_542984.2|refseq:XP_006724089.1 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 rogid:yolHEKnYRC1KwprZYyWZXZmjgr89606 rigid:Z2UMy1yH+GoQwgACJ+BNsyjjR+M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P22492 uniprotkb:Q70CQ2 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 intact:EBI-6256020|uniprotkb:A8MWD0|uniprotkb:B3KWU9|uniprotkb:O60316|uniprotkb:O94834|uniprotkb:Q3B777|uniprotkb:Q6P6C9|uniprotkb:Q7L8P6|uniprotkb:Q8N3T9|uniprotkb:Q8TBW2|uniprotkb:Q9UGA1|ensembl:ENSP00000381577 psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:ubp34_human(display_long)|uniprotkb:USP34(gene name)|psi-mi:USP34(display_short)|uniprotkb:KIAA0570(gene name synonym)|uniprotkb:KIAA0729(gene name synonym)|uniprotkb:Deubiquitinating enzyme 34(gene name synonym)|uniprotkb:Ubiquitin thioesterase 34(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 34(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479342|imex:IM-26985-247 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492 refseq:NP_055524.3|ensembl:ENSG00000115464(gene)|ensembl:ENST00000398571(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018200|interpro:IPR021905|interpro:IPR028889|interpro:IPR038765|mint:Q70CQ2|reactome:R-HSA-201681|reactome:R-HSA-5689880 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 rogid:ouPBRH6ndkATju67iwZYOl1wYWM9606 rigid:Z2UMy1yH+GoQwgACJ+BNsyjjR+M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P22492 uniprotkb:Q9Y3T9 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 intact:EBI-751547|uniprotkb:Q5SVA3|uniprotkb:Q9BTN6|ensembl:ENSP00000317992 psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:noc2l_human(display_long)|uniprotkb:NOC2-like protein(gene name synonym)|uniprotkb:NOC2L(gene name)|psi-mi:NOC2L(display_short)|uniprotkb:NIR(gene name synonym)|uniprotkb:Novel INHAT repressor(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479342|imex:IM-26985-247 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492 refseq:NP_056473.2|ensembl:ENSG00000188976(gene)|ensembl:ENST00000327044(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002903"(negative regulation of B cell apoptotic process)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0030690"(Noc1p-Noc2p complex)|go:"GO:0030691"(Noc2p-Noc3p complex)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031497"(chromatin assembly)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR005343(Protein of unknown function UPF0120)|interpro:IPR016024(Armadillo-type fold)|mint:Q9Y3T9|reactome:R-HSA-6804756 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 rogid:3QFBiahYEZ0/0O6A+SxvTO2kO0Y9606 rigid:Z2UMy1yH+GoQwgACJ+BNsyjjR+M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P22492 uniprotkb:Q15061 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 intact:EBI-2563523|uniprotkb:Q92577|uniprotkb:Q15395|ensembl:ENSP00000384302 psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:wdr43_human(display_long)|uniprotkb:WDR43(gene name)|psi-mi:WDR43(display_short)|uniprotkb:KIAA0007(gene name synonym)|uniprotkb:UTP5(gene name synonym)|uniprotkb:U3 small nucleolar RNA-associated protein 5 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479342|imex:IM-26985-247 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492 refseq:NP_055946.1|ensembl:ENSG00000163811(gene)|ensembl:ENST00000407426(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0003711"(transcription elongation regulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR001680(WD40 repeat)|interpro:IPR007148(Small-subunit processome, Utp12)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q15061|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 rogid:5YWzMczifqbhFvvX1HkF3XYW6xA9606 rigid:Z2UMy1yH+GoQwgACJ+BNsyjjR+M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P22492 uniprotkb:P09661 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 intact:EBI-876439|uniprotkb:Q8TBD2|uniprotkb:B2R5I6|ensembl:ENSP00000254193 psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:ru2a_human(display_long)|uniprotkb:SNRPA1(gene name)|psi-mi:SNRPA1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479342|imex:IM-26985-247 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492 refseq:NP_003081.2|dip:DIP-625N|ensembl:ENSG00000131876(gene)|ensembl:ENST00000254193(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR032675|interpro:IPR044640|mint:P09661|rcsb pdb:1A9N|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|reactome:R-HSA-72163|reactome:R-HSA-8950505 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 rogid:tmZyAPCvMg34GY4kVc6NcnycOeE9606 rigid:Z2UMy1yH+GoQwgACJ+BNsyjjR+M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P22492 uniprotkb:Q12888 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 intact:EBI-396540|uniprotkb:Q2M1Z7|uniprotkb:Q4LE46|uniprotkb:Q5FWZ3|uniprotkb:Q7Z3U4|ensembl:ENSP00000263801|uniprotkb:F8VY86 psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:tp53b_human(display_long)|uniprotkb:TP53BP1(gene name)|psi-mi:TP53BP1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479342|imex:IM-26985-247 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492 refseq:NP_001135451.1|refseq:NP_001135452.1|refseq:NP_005648.1|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0042393"(histone binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061649"(ubiquitin modification-dependent histone binding)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:1990391"(DNA repair complex)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|interpro:IPR001357(BRCT)|interpro:IPR002999(Tudor)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR015125(Tumour suppressor p53-binding protein-1 Tudor)|interpro:IPR036420|mint:Q12888|reactome:R-HSA-5693607|reactome:R-HSA-69473|rcsb pdb:1GZH|rcsb pdb:1KZY|rcsb pdb:1XNI|rcsb pdb:2G3R|rcsb pdb:2IG0|rcsb pdb:2LVM|rcsb pdb:2MWO|rcsb pdb:2MWP|rcsb pdb:3LGF|rcsb pdb:3LGL|rcsb pdb:3LH0|rcsb pdb:4CRI|rcsb pdb:4RG2|rcsb pdb:4X34|rcsb pdb:5ECG|rcsb pdb:5J26|rcsb pdb:5KGF|rcsb pdb:5Z78|rcsb pdb:5ZCJ|rcsb pdb:6CO1|rcsb pdb:6CO2|rcsb pdb:6IU7|rcsb pdb:6IUA|rcsb pdb:6MXX|rcsb pdb:6MXY|rcsb pdb:6MXZ|rcsb pdb:6MY0|rcsb pdb:6RML|rcsb pdb:6RMM|rcsb pdb:6UPT|rcsb pdb:6VA5|rcsb pdb:6VIP|rcsb pdb:7LIN|rcsb pdb:7LIO|reactome:R-HSA-3232118|reactome:R-HSA-5693565|reactome:R-HSA-5693571|ensembl:ENSG00000067369(gene)|ensembl:ENST00000263801(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000776"(kinetochore)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0002039"(p53 binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042162"(telomeric DNA binding)|dip:DIP-5978N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 rogid:QRksPL7aJniN+0thiLfIdeythoU9606 rigid:Z2UMy1yH+GoQwgACJ+BNsyjjR+M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P22492 uniprotkb:Q6ZRS2 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 intact:EBI-769316|uniprotkb:O15026|uniprotkb:Q7Z744|uniprotkb:Q9Y5L9|uniprotkb:B0JZA6|intact:EBI-28987488|ensembl:ENSP00000262518 psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:srcap_human(display_long)|uniprotkb:KIAA0309(gene name synonym)|uniprotkb:Snf2-related CBP activator(gene name synonym)|uniprotkb:Domino homolog 2(gene name synonym)|uniprotkb:SRCAP(gene name)|psi-mi:SRCAP(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479342|imex:IM-26985-247 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492 refseq:NP_006653.2|ensembl:ENSP00000262518|dip:DIP-45191N|go:"GO:0043044"|go:"GO:0043486"(histone exchange)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR017956|interpro:IPR027417|interpro:IPR038718|mint:Q6ZRS2|rcsb pdb:6IGM|ensembl:ENSG00000080603(gene)|ensembl:ENST00000262518(transcript)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004386"(helicase activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding) - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 rogid:B02tJyhpU10j4ToMVJFMSCxonzM9606 rigid:Z2UMy1yH+GoQwgACJ+BNsyjjR+M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P22492 uniprotkb:Q9BV38 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 intact:EBI-727429|uniprotkb:O60390|uniprotkb:Q9BWR2|intact:EBI-28969560|ensembl:ENSP00000476117 psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:wdr18_human(display_long)|uniprotkb:WDR18(gene name)|psi-mi:WDR18(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479342|imex:IM-26985-247 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492 refseq:NP_077005.2|ensembl:ENSP00000476117|go:"GO:0097344"(Rix1 complex)|go:"GO:0120293"(dynein axonemal particle)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR026987|interpro:IPR036322|mint:Q9BV38|reactome:R-HSA-6791226|ensembl:ENSG00000065268(gene)|ensembl:ENST00000585809(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation) - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 rogid:03RKz4c6MKJvOePaNrKeInnS6Lg9606 rigid:Z2UMy1yH+GoQwgACJ+BNsyjjR+M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P22492 uniprotkb:Q99733 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 intact:EBI-2255116|uniprotkb:B2R6J4|uniprotkb:F5HFY4|ensembl:ENSP00000369915|ensembl:ENSP00000483728 psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:np1l4_human(display_long)|uniprotkb:NAP1L4(gene name)|psi-mi:NAP1L4(display_short)|uniprotkb:NAP2(gene name synonym)|uniprotkb:Nucleosome assembly protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479342|imex:IM-26985-247 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492 refseq:NP_005960.1|ensembl:ENSG00000205531(gene)|ensembl:ENSG00000273562(gene)|ensembl:ENST00000380542(transcript)|ensembl:ENST00000619695(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031491"(nucleosome binding)|go:"GO:0042393"(histone binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q99733 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 rogid:tES8IJDlW4JONR/pdC8dq49I/7Y9606 rigid:Z2UMy1yH+GoQwgACJ+BNsyjjR+M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P22492 uniprotkb:Q8N983 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 intact:EBI-1043145|ensembl:ENSP00000315364|uniprotkb:Q5JW06|uniprotkb:Q7Z719|uniprotkb:Q7Z7H6|uniprotkb:Q86XN1|uniprotkb:Q9BYC7|uniprotkb:B1AL09|uniprotkb:B1AL07|uniprotkb:B1AL10|intact:EBI-1047104|uniprotkb:D3DR71|uniprotkb:B1AL06|uniprotkb:C9J5Q3 psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:rm43_human(display_long)|uniprotkb:Mitochondrial ribosomal protein bMRP36a(gene name synonym)|uniprotkb:MRPL43(gene name)|psi-mi:MRPL43(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein mL43(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479342|imex:IM-26985-247 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492 rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|ensembl:ENSG00000055950(gene)|ensembl:ENST00000318325(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR007741(Mitochondrial ribosome)|interpro:IPR036249|interpro:IPR039927|mint:Q8N983|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:7A5I|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|refseq:NP_789764.1|refseq:XP_006718098.1|refseq:NP_115488.2|refseq:NP_789762.1|refseq:NP_789763.1|refseq:NP_001295325.1|ensembl:ENST00000299179|ensembl:ENSP00000299179|ensembl:ENSP00000315364|ensembl:ENST00000318364|ensembl:ENSP00000315948|ensembl:ENST00000342071|ensembl:ENSP00000339844|ensembl:ENST00000370234|ensembl:ENSP00000359254|ensembl:ENST00000370236|ensembl:ENSP00000359256|ensembl:ENST00000370242|ensembl:ENSP00000359262|refseq:XP_005270288.1 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 rogid:p3wPkljBAhx4IwvXsvfXDaEvpag9606 rigid:Z2UMy1yH+GoQwgACJ+BNsyjjR+M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P22492 uniprotkb:Q9BYD3 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 intact:EBI-721368|uniprotkb:A6NNV7|uniprotkb:Q9BW07|uniprotkb:Q9H4N2|uniprotkb:Q9Y317|ensembl:ENSP00000253099|ensembl:ENSP00000306902 psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:rm04_human(display_long)|uniprotkb:MRPL4(gene name)|psi-mi:MRPL4(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein uL4m(gene name synonym)|uniprotkb:CDABP0091(orf name)|uniprotkb:CGI-28(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479342|imex:IM-26985-247 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492 refseq:NP_057040.2|refseq:NP_666499.1|refseq:NP_666500.1|ensembl:ENSG00000105364(gene)|ensembl:ENST00000253099(transcript)|ensembl:ENST00000307422(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|interpro:IPR002136(Ribosomal protein L4/L1e)|interpro:IPR013005(Ribosomal protein L4/L1e, bacterial-type)|interpro:IPR023574|mint:Q9BYD3|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 rogid:v1MODeAQQcG4MKCE/hvEg2NBwmk9606 rigid:Z2UMy1yH+GoQwgACJ+BNsyjjR+M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P22492 uniprotkb:P49406 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 intact:EBI-1188518|uniprotkb:Q96Q52|uniprotkb:Q53TX9|ensembl:ENSP00000377486|ensembl:ENSP00000387284 psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:rm19_human(display_long)|uniprotkb:MRPL15(gene name synonym)|uniprotkb:39S ribosomal protein L15, mitochondrial(gene name synonym)|uniprotkb:MRPL19(gene name)|psi-mi:MRPL19(display_short)|uniprotkb:KIAA0104(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein bL19m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479342|imex:IM-26985-247 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492 refseq:NP_055578.2|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:7O9M|ensembl:ENSG00000115364(gene)|ensembl:ENST00000393909(transcript)|ensembl:ENST00000409374(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|interpro:IPR001857(Ribosomal protein L19)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR038657|mint:P49406|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 rogid:4ZCZpq3u9wkdpuNVFpk+bhceaW09606 rigid:Z2UMy1yH+GoQwgACJ+BNsyjjR+M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P22492 uniprotkb:Q9H9J2 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 intact:EBI-713619|uniprotkb:Q53S16|uniprotkb:Q6IA62|uniprotkb:Q9H821|ensembl:ENSP00000258383|intact:EBI-21356011 psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:rm44_human(display_long)|uniprotkb:MRPL44(gene name)|psi-mi:MRPL44(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein mL44(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479342|imex:IM-26985-247 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492 ensembl:ENSG00000135900(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004525"(ribonuclease III activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0005886"(plasma membrane)|go:"GO:0006396"(RNA processing)|go:"GO:0016604"(nuclear body)|go:"GO:0030422"(production of siRNA involved in RNA interference)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0070125"(mitochondrial translational elongation)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR036389|interpro:IPR044444|mint:Q9H9J2|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|ensembl:ENST00000258383(transcript)|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:NP_075066.1 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 rogid:YNUNu4UGyhAuaSChEzFXCw2k7wk9606 rigid:Z2UMy1yH+GoQwgACJ+BNsyjjR+M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P22492 uniprotkb:P62995 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 intact:EBI-725485|uniprotkb:O15449|uniprotkb:Q15815|uniprotkb:Q64283|uniprotkb:B4DVK2|uniprotkb:D3DNU3|ensembl:ENSP00000416959 psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:tra2b_human(display_long)|uniprotkb:TRA2B(gene name)|psi-mi:TRA2B(display_short)|uniprotkb:SFRS10(gene name synonym)|uniprotkb:Transformer-2 protein homolog B(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 10(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479342|imex:IM-26985-247 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492 refseq:NP_004584.1|refseq:XP_005247760.1|refseq:NP_001230808.1|refseq:XP_011511374.1|ensembl:ENSG00000136527(gene)|ensembl:ENST00000453386(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:1990403"(embryonic brain development)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P62995|rcsb pdb:2CQC|rcsb pdb:2KXN|rcsb pdb:2RRA|rcsb pdb:2RRB|reactome:R-HSA-72163|reactome:R-HSA-9013418|reactome:R-HSA-9013422|refseq:XP_016862522.1|dip:DIP-42278N - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 rogid:6uZGeHEDlIVsb2uPeo+9NoR4tDw9606 rigid:Z2UMy1yH+GoQwgACJ+BNsyjjR+M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P22492 uniprotkb:P07199 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 intact:EBI-949451|intact:EBI-28970331|ensembl:ENSP00000369075|uniprotkb:Q96EI4 psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:cenpb_human(display_long)|uniprotkb:Centromere protein B(gene name synonym)|uniprotkb:CENPB(gene name)|psi-mi:CENPB(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479342|imex:IM-26985-247 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492 ensembl:ENSP00000369075|ensembl:ENSG00000125817(gene)|ensembl:ENST00000379751(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003696"(satellite DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0016604"(nuclear body)|go:"GO:0019237"(centromeric DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR004875(CENP-B protein)|interpro:IPR006600(Centromere protein B, helix-turn-helix)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015115(Centromere protein B dimerisation)|interpro:IPR033062|interpro:IPR034882|mint:P07199|rcsb pdb:1BW6|rcsb pdb:1HLV|rcsb pdb:1UFI|rcsb pdb:6KDR|refseq:NP_001801.1 - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 rogid:+03fJP9KYbjMxvL/JrO0Wj4+MJs9606 rigid:Z2UMy1yH+GoQwgACJ+BNsyjjR+M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P22492 uniprotkb:Q13242 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 intact:EBI-2949710|ensembl:ENSP00000229390|uniprotkb:Q52LD1 psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:srsf9_human(display_long)|uniprotkb:SRSF9(gene name)|psi-mi:SRSF9(display_short)|uniprotkb:SFRS9(gene name synonym)|uniprotkb:SRP30C(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SRp30C(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479342|imex:IM-26985-247 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492 go:"GO:0006397"(mRNA processing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043279"(response to alkaloid)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|go:"GO:0006376"(mRNA splice site selection)|interpro:IPR034503|interpro:IPR034995|interpro:IPR035979|mint:Q13242|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|ensembl:ENSG00000111786(gene)|ensembl:ENST00000229390(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|refseq:NP_003760.1|dip:DIP-40741N - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 rogid:9x6TWFk1zN1YodjXBiwi/MtNJe49606 rigid:Z2UMy1yH+GoQwgACJ+BNsyjjR+M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P22492 uniprotkb:Q9H0U6 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 intact:EBI-2560240|uniprotkb:Q5TAP9|uniprotkb:Q9NZW8|ensembl:ENSP00000356001 psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:rm18_human(display_long)|uniprotkb:MRPL18(gene name)|psi-mi:MRPL18(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein uL18m(gene name synonym)|uniprotkb:HSPC071(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479342|imex:IM-26985-247 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492 refseq:NP_054880.2|ensembl:ENSG00000112110(gene)|ensembl:ENST00000367034(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005615"(extracellular space)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0035928"(rRNA import into mitochondrion)|interpro:IPR005484(Ribosomal protein L18/L5)|interpro:IPR036967|mint:Q9H0U6|rcsb pdb:3J7Y|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:NP_001305746.1|dip:DIP-56844N - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 rogid:MtxdrTVdqAfWZqnuxD+PGs218/A9606 rigid:Z2UMy1yH+GoQwgACJ+BNsyjjR+M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P22492 uniprotkb:Q9NPF5 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 intact:EBI-399105|uniprotkb:Q0JSM4|uniprotkb:Q5TG41|uniprotkb:Q7Z3H7|uniprotkb:Q9H0S8|uniprotkb:Q9P2C2|uniprotkb:A8K001|uniprotkb:D3DPY8|ensembl:ENSP00000312697|ensembl:ENSP00000354697|ensembl:ENSP00000361363 psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:dmap1_human(display_long)|uniprotkb:DMAP1(gene name)|psi-mi:DMAP1(display_short)|uniprotkb:KIAA1425(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479342|imex:IM-26985-247 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492 refseq:NP_001029195.1|refseq:NP_001029196.1|refseq:NP_061973.1|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR008468(DNA methyltransferase 1-associated 1)|interpro:IPR027109|interpro:IPR032563|mint:Q9NPF5|rcsb pdb:3HM5|rcsb pdb:4IEJ|reactome:R-HSA-3214847|ensembl:ENSG00000178028(gene)|ensembl:ENST00000315913(transcript)|ensembl:ENST00000361745(transcript)|ensembl:ENST00000372289(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000812"(Swr1 complex)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006306"(DNA methylation)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043486"(histone exchange)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045471"(response to ethanol)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|refseq:XP_016857297.1 - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 rogid:ujgZ1NbKKo/pw//CZvIGWfY2ob49606 rigid:Z2UMy1yH+GoQwgACJ+BNsyjjR+M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P22492 uniprotkb:Q9BYC9 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 intact:EBI-714361|uniprotkb:B2RE41|ensembl:ENSP00000341082|uniprotkb:B7Z746 psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:rm20_human(display_long)|uniprotkb:MRPL20(gene name)|psi-mi:MRPL20(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein bL20m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479342|imex:IM-26985-247 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492 rcsb pdb:7OF4|rcsb pdb:7OG4|refseq:NP_060441.2|ensembl:ENSG00000242485(gene)|ensembl:ENST00000344843(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|interpro:IPR005813(Ribosomal protein L20)|interpro:IPR035566|mint:Q9BYC9|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:6VMI|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - comment:"author score: 33" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 rogid:x96Ntk82ZbcbF8ksg84k0sHgINc9606 rigid:Z2UMy1yH+GoQwgACJ+BNsyjjR+M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P22492 uniprotkb:Q68CQ4 intact:EBI-1056618|uniprotkb:Q6ISI1|uniprotkb:Q8IUE8|ensembl:ENSP00000341214 intact:EBI-747711|uniprotkb:Q4VY00|uniprotkb:O75992|uniprotkb:Q63HL9|ensembl:ENSP00000419005 psi-mi:h1t_human(display_long)|uniprotkb:H1-6(gene name)|psi-mi:H1-6(display_short)|uniprotkb:H1FT(gene name synonym)|uniprotkb:H1T(gene name synonym)|uniprotkb:HIST1H1T(gene name synonym)|uniprotkb:Testicular H1 histone(gene name synonym) psi-mi:utp25_human(display_long)|uniprotkb:UTP25(gene name)|psi-mi:UTP25(display_short)|uniprotkb:C1orf107(gene name synonym)|uniprotkb:DEF(gene name synonym)|uniprotkb:DIEXF(gene name synonym)|uniprotkb:Digestive organ expansion factor homolog(gene name synonym)|uniprotkb:UTP25 small subunit processor component(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479342|imex:IM-26985-247 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005314.2|ensembl:ENSG00000187475(gene)|ensembl:ENST00000338379(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030154"(cell differentiation)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P22492 refseq:NP_055203.4|ensembl:ENSG00000117597(gene)|ensembl:ENST00000491415(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0019843"(rRNA binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031648"(protein destabilization)|go:"GO:0032040"(small-subunit processome)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0048568"(embryonic organ development)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR010678(Protein of unknown function DUF1253)|interpro:IPR027417|mint:Q68CQ4|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - comment:"author score: 37" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TC76lMws8QJeKcatF/48D0u1yi49606 rogid:d07Twpovf9qDORx92HViyMP+wLs9606 rigid:Z2UMy1yH+GoQwgACJ+BNsyjjR+M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BW71 uniprotkb:P35249 intact:EBI-723624|uniprotkb:O75707|uniprotkb:O75708|ensembl:ENSP00000279392|uniprotkb:H3BSR3 intact:EBI-476655|uniprotkb:Q6FHX7|ensembl:ENSP00000296273|ensembl:ENSP00000376272|uniprotkb:D3DNV2|uniprotkb:B4DM41 psi-mi:hirp3_human(display_long)|uniprotkb:HIRIP3(gene name)|psi-mi:HIRIP3(display_short) psi-mi:rfc4_human(display_long)|uniprotkb:Activator 1 subunit 4(gene name synonym)|uniprotkb:Replication factor C 37 kDa subunit(gene name synonym)|uniprotkb:Activator 1 37 kDa subunit(gene name synonym)|uniprotkb:RFC4(gene name)|psi-mi:RFC4(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479309|imex:IM-26985-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003600.2|ensembl:ENSG00000149929(gene)|ensembl:ENST00000279392(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006333"(chromatin assembly or disassembly)|interpro:IPR019098|interpro:IPR037647|mint:Q9BW71|refseq:NP_001184252.1 refseq:NP_002907.1|refseq:NP_853551.1|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|ensembl:ENSG00000163918(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0031391"(Elg1 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|ensembl:ENST00000296273(transcript)|ensembl:ENST00000392481(transcript)|mint:P35249|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804756|reactome:R-HSA-69091|reactome:R-HSA-69473|reactome:R-HSA-176187|dip:DIP-24267N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:NaB5i2oZ7MCfCvw+Vc0eC6u5B+s9606 rogid:zn+V998ZRpYIdHmG87ExC6LFc0w9606 rigid:hHDQ06AfiG6+8wRg6fmEBO4fLEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BW71 uniprotkb:P16104 intact:EBI-723624|uniprotkb:O75707|uniprotkb:O75708|ensembl:ENSP00000279392|uniprotkb:H3BSR3 intact:EBI-494830|uniprotkb:Q4ZGJ7|uniprotkb:Q6IAS5|ensembl:ENSP00000364310|ensembl:ENSP00000434024 psi-mi:hirp3_human(display_long)|uniprotkb:HIRIP3(gene name)|psi-mi:HIRIP3(display_short) psi-mi:h2ax_human(display_long)|uniprotkb:H2AX(gene name)|psi-mi:H2AX(display_short)|uniprotkb:H2AFX(gene name synonym)|uniprotkb:Histone H2A.X(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479309|imex:IM-26985-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003600.2|ensembl:ENSG00000149929(gene)|ensembl:ENST00000279392(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006333"(chromatin assembly or disassembly)|interpro:IPR019098|interpro:IPR037647|mint:Q9BW71|refseq:NP_001184252.1 ensembl:ENSG00000188486(gene)|ensembl:ENST00000375167(transcript)|ensembl:ENST00000530167(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000786"(nucleosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|refseq:NP_002096.1|dip:DIP-33604N|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|go:"GO:0005813"(centrosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090398"(cellular senescence)|go:"GO:0090734"(site of DNA damage)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P16104|rcsb pdb:1YDP|rcsb pdb:2AZM|rcsb pdb:2D31|rcsb pdb:2DYP|rcsb pdb:3SHV|rcsb pdb:3SQD|rcsb pdb:3SZM|rcsb pdb:3U3Z|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:NaB5i2oZ7MCfCvw+Vc0eC6u5B+s9606 rogid:VQoEp3F8lEBTOj+PDDUzrJCQNZA9606 rigid:hHDQ06AfiG6+8wRg6fmEBO4fLEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BW71 uniprotkb:P49458 intact:EBI-723624|uniprotkb:O75707|uniprotkb:O75708|ensembl:ENSP00000279392|uniprotkb:H3BSR3 intact:EBI-350743|uniprotkb:Q6NVX0|uniprotkb:Q8WTW0|ensembl:ENSP00000305230|uniprotkb:A8K0N0 psi-mi:hirp3_human(display_long)|uniprotkb:HIRIP3(gene name)|psi-mi:HIRIP3(display_short) psi-mi:srp09_human(display_long)|uniprotkb:SRP9(gene name)|psi-mi:SRP9(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479309|imex:IM-26985-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003600.2|ensembl:ENSG00000149929(gene)|ensembl:ENST00000279392(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006333"(chromatin assembly or disassembly)|interpro:IPR019098|interpro:IPR037647|mint:Q9BW71|refseq:NP_001184252.1 rcsb pdb:4UYJ|refseq:NP_001123912.1|refseq:NP_003124.1|ensembl:ENSG00000143742(gene)|ensembl:ENST00000304786(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005785"(signal recognition particle receptor complex)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|go:"GO:0045900"(negative regulation of translational elongation)|interpro:IPR008832(Signal recognition particle, SRP9 subunit)|interpro:IPR009018(Signal recognition particle, SRP9/SRP14 subunit)|interpro:IPR039432|interpro:IPR039914|mint:P49458|rcsb pdb:1E8O|rcsb pdb:1E8S|rcsb pdb:1RY1|rcsb pdb:4UYK|rcsb pdb:5AOX|rcsb pdb:7NFX|reactome:R-HSA-1799339|dip:DIP-6151N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:NaB5i2oZ7MCfCvw+Vc0eC6u5B+s9606 rogid:Y33fEeeXnma9oF7Fzs6zEGQjVBU9606 rigid:hHDQ06AfiG6+8wRg6fmEBO4fLEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BW71 uniprotkb:P39687 intact:EBI-723624|uniprotkb:O75707|uniprotkb:O75708|ensembl:ENSP00000279392|uniprotkb:H3BSR3 intact:EBI-359234|uniprotkb:Q53FK4|uniprotkb:Q5J8L8|uniprotkb:Q7M4N6|uniprotkb:B2R6T4|ensembl:ENSP00000417864 psi-mi:hirp3_human(display_long)|uniprotkb:HIRIP3(gene name)|psi-mi:HIRIP3(display_short) psi-mi:an32a_human(display_long)|uniprotkb:ANP32A(gene name)|psi-mi:ANP32A(display_short)|uniprotkb:LANP(gene name synonym)|uniprotkb:PHAP1(gene name synonym)|uniprotkb:C15orf1(gene name synonym)|uniprotkb:MAPM(gene name synonym)|uniprotkb:Potent heat-stable protein phosphatase 2A inhibitor I1PP2A(gene name synonym)|uniprotkb:Acidic nuclear phosphoprotein pp32(gene name synonym)|uniprotkb:Leucine-rich acidic nuclear protein(gene name synonym)|uniprotkb:Putative HLA-DR-associated protein I(gene name synonym)|uniprotkb:Mapmodulin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479309|imex:IM-26985-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003600.2|ensembl:ENSG00000149929(gene)|ensembl:ENST00000279392(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006333"(chromatin assembly or disassembly)|interpro:IPR019098|interpro:IPR037647|mint:Q9BW71|refseq:NP_001184252.1 refseq:NP_006296.1|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR032675|mint:P39687|rcsb pdb:2JE0|rcsb pdb:2JE1|rcsb pdb:4XOS|rcsb pdb:6XZQ|reactome:R-HSA-450520|ensembl:ENSG00000140350(gene)|ensembl:ENST00000465139(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm) - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:NaB5i2oZ7MCfCvw+Vc0eC6u5B+s9606 rogid:uyR/0ZiQuJsE2V1LbRJQiLs+IH49606 rigid:hHDQ06AfiG6+8wRg6fmEBO4fLEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BW71 uniprotkb:P68400 intact:EBI-723624|uniprotkb:O75707|uniprotkb:O75708|ensembl:ENSP00000279392|uniprotkb:H3BSR3 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 psi-mi:hirp3_human(display_long)|uniprotkb:HIRIP3(gene name)|psi-mi:HIRIP3(display_short) psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479309|imex:IM-26985-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003600.2|ensembl:ENSG00000149929(gene)|ensembl:ENST00000279392(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006333"(chromatin assembly or disassembly)|interpro:IPR019098|interpro:IPR037647|mint:Q9BW71|refseq:NP_001184252.1 rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:NaB5i2oZ7MCfCvw+Vc0eC6u5B+s9606 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 rigid:hHDQ06AfiG6+8wRg6fmEBO4fLEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BW71 uniprotkb:P49736 intact:EBI-723624|uniprotkb:O75707|uniprotkb:O75708|ensembl:ENSP00000279392|uniprotkb:H3BSR3 intact:EBI-374819|uniprotkb:Q14577|uniprotkb:Q15023|uniprotkb:Q8N2V1|uniprotkb:Q969W7|uniprotkb:Q96AE1|uniprotkb:Q9BRM7|ensembl:ENSP00000265056 psi-mi:hirp3_human(display_long)|uniprotkb:HIRIP3(gene name)|psi-mi:HIRIP3(display_short) psi-mi:mcm2_human(display_long)|uniprotkb:MCM2(gene name)|psi-mi:MCM2(display_short)|uniprotkb:BM28(gene name synonym)|uniprotkb:CDCL1(gene name synonym)|uniprotkb:KIAA0030(gene name synonym)|uniprotkb:Minichromosome maintenance protein 2 homolog(gene name synonym)|uniprotkb:Nuclear protein BM28(gene name synonym)|uniprotkb:CCNL1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479309|imex:IM-26985-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003600.2|ensembl:ENSG00000149929(gene)|ensembl:ENST00000279392(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006333"(chromatin assembly or disassembly)|interpro:IPR019098|interpro:IPR037647|mint:Q9BW71|refseq:NP_001184252.1 ensembl:ENSG00000073111(gene)|ensembl:ENST00000265056(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006915"(apoptotic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0042393"(histone binding)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090102"(cochlea development)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P49736|rcsb pdb:4UUZ|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5JA4|rcsb pdb:6XTX|rcsb pdb:6XTY|rcsb pdb:6YA7|rcsb pdb:7CIZ|rcsb pdb:7CJ0|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|refseq:NP_004517.2|dip:DIP-31732N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:NaB5i2oZ7MCfCvw+Vc0eC6u5B+s9606 rogid:Jt9ODNyJBwtwQ0pb/+X46vtHfE09606 rigid:hHDQ06AfiG6+8wRg6fmEBO4fLEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BW71 uniprotkb:P19784 intact:EBI-723624|uniprotkb:O75707|uniprotkb:O75708|ensembl:ENSP00000279392|uniprotkb:H3BSR3 intact:EBI-347451|ensembl:ENSP00000262506 psi-mi:hirp3_human(display_long)|uniprotkb:HIRIP3(gene name)|psi-mi:HIRIP3(display_short) psi-mi:csk22_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)|uniprotkb:CK2A2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479309|imex:IM-26985-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003600.2|ensembl:ENSG00000149929(gene)|ensembl:ENST00000279392(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006333"(chromatin assembly or disassembly)|interpro:IPR019098|interpro:IPR037647|mint:Q9BW71|refseq:NP_001184252.1 refseq:NP_001887.1|dip:DIP-318N|ensembl:ENSG00000070770(gene)|ensembl:ENST00000262506(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19784|rcsb pdb:3E3B|rcsb pdb:3OFM|rcsb pdb:3U87|rcsb pdb:5M4U|rcsb pdb:5M56|rcsb pdb:5OOI|rcsb pdb:5Y9M|rcsb pdb:5YF9|rcsb pdb:5YWM|rcsb pdb:6HMB|rcsb pdb:6HMC|rcsb pdb:6HMD|rcsb pdb:6HMQ|rcsb pdb:6L20|rcsb pdb:6QY8|rcsb pdb:6QY9|rcsb pdb:6TE2|rcsb pdb:6TEW|rcsb pdb:6TGU|rcsb pdb:7A1B|rcsb pdb:7A1Z|rcsb pdb:7A22|rcsb pdb:7A2H|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:NaB5i2oZ7MCfCvw+Vc0eC6u5B+s9606 rogid:SIekW2yzNePP9hLKW7OHNFBwNck9606 rigid:hHDQ06AfiG6+8wRg6fmEBO4fLEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BW71 uniprotkb:Q9Y281 intact:EBI-723624|uniprotkb:O75707|uniprotkb:O75708|ensembl:ENSP00000279392|uniprotkb:H3BSR3 intact:EBI-351218|uniprotkb:G3V5P4|ensembl:ENSP00000298159|ensembl:ENSP00000340635|ensembl:ENSP00000500375|ensembl:ENSP00000500532 psi-mi:hirp3_human(display_long)|uniprotkb:HIRIP3(gene name)|psi-mi:HIRIP3(display_short) psi-mi:cof2_human(display_long)|uniprotkb:CFL2(gene name)|psi-mi:CFL2(display_short)|uniprotkb:Cofilin, muscle isoform(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479309|imex:IM-26985-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003600.2|ensembl:ENSG00000149929(gene)|ensembl:ENST00000279392(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006333"(chromatin assembly or disassembly)|interpro:IPR019098|interpro:IPR037647|mint:Q9BW71|refseq:NP_001184252.1 refseq:NP_068733.1|refseq:NP_619579.1|refseq:XP_011534665.1|refseq:NP_001230574.1|dip:DIP-33178N|ensembl:ENSG00000165410(gene)|ensembl:ENST00000298159(transcript)|ensembl:ENST00000341223(transcript)|ensembl:ENST00000672163(transcript)|ensembl:ENST00000672517(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030018"(Z disc)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0031674"(I band)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048870"(cell motility)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR029006|mint:Q9Y281 - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:NaB5i2oZ7MCfCvw+Vc0eC6u5B+s9606 rogid:HwYoUPZRkuRzqMLvuQctwNCOREA9606 rigid:hHDQ06AfiG6+8wRg6fmEBO4fLEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BW71 uniprotkb:P67870 intact:EBI-723624|uniprotkb:O75707|uniprotkb:O75708|ensembl:ENSP00000279392|uniprotkb:H3BSR3 intact:EBI-348169|ensembl:ENSP00000365025|ensembl:ENSP00000365026|ensembl:ENSP00000365042|ensembl:ENSP00000372919|ensembl:ENSP00000372925|ensembl:ENSP00000382980|ensembl:ENSP00000390900|ensembl:ENSP00000391038|ensembl:ENSP00000393756|ensembl:ENSP00000394855|ensembl:ENSP00000395275|ensembl:ENSP00000400188|ensembl:ENSP00000407018|ensembl:ENSP00000407379|ensembl:ENSP00000409510|ensembl:ENSP00000410802|ensembl:ENSP00000411322|ensembl:ENSP00000412520|ensembl:ENSP00000413469|ensembl:ENSP00000415237|ensembl:ENSP00000415303|uniprotkb:P07312|uniprotkb:P13862|uniprotkb:Q4VX47|intact:EBI-3866975|uniprotkb:B0UXA9 psi-mi:hirp3_human(display_long)|uniprotkb:HIRIP3(gene name)|psi-mi:HIRIP3(display_short) psi-mi:csk2b_human(display_long)|uniprotkb:Phosvitin(gene name synonym)|uniprotkb:Protein G5a(gene name synonym)|uniprotkb:CSNK2B(gene name)|psi-mi:CSNK2B(display_short)|uniprotkb:CK2N(gene name synonym)|uniprotkb:G5A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479309|imex:IM-26985-21 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003600.2|ensembl:ENSG00000149929(gene)|ensembl:ENST00000279392(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006333"(chromatin assembly or disassembly)|interpro:IPR019098|interpro:IPR037647|mint:Q9BW71|refseq:NP_001184252.1 ensembl:ENSG00000204435(gene)|ensembl:ENSG00000230700(gene)|ensembl:ENSG00000206406(gene)|ensembl:ENSG00000232960(gene)|ensembl:ENSG00000224398(gene)|ensembl:ENSG00000224774(gene)|ensembl:ENSG00000228875(gene)|ensembl:ENST00000375882(transcript)|ensembl:ENST00000383427(transcript)|ensembl:ENST00000383433(transcript)|ensembl:ENST00000400110(transcript)|ensembl:ENST00000412802(transcript)|ensembl:ENST00000418230(transcript)|ensembl:ENST00000422567(transcript)|ensembl:ENST00000429633(transcript)|ensembl:ENST00000431476(transcript)|ensembl:ENST00000436169(transcript)|ensembl:ENST00000443673(transcript)|ensembl:ENST00000448596(transcript)|ensembl:ENST00000451917(transcript)|ensembl:ENST00000452985(transcript)|ensembl:ENST00000453234(transcript)|ensembl:ENST00000454382(transcript)|ensembl:ENST00000454511(transcript)|ensembl:ENST00000455161(transcript)|ensembl:ENST00000458330(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0007165"(signal transduction)|ensembl:ENST00000375865(transcript)|ensembl:ENST00000375866(transcript)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016363"(nuclear matrix)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032927"(positive regulation of activin receptor signaling pathway)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0033574"(response to testosterone)|go:"GO:0034622"|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR035991|mint:P67870|rcsb pdb:1DS5|rcsb pdb:1JWH|go:"GO:0008134"(transcription factor binding)|rcsb pdb:1QF8|rcsb pdb:3EED|rcsb pdb:4DGL|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6798695|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:6Q38|refseq:NP_001311.3|refseq:NP_001269314.1|dip:DIP-131N - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:NaB5i2oZ7MCfCvw+Vc0eC6u5B+s9606 rogid:ZTHJjCqHg2dE7B+WoSU28VSMuPg9606 rigid:hHDQ06AfiG6+8wRg6fmEBO4fLEg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NWT6 uniprotkb:Q05823 intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69 intact:EBI-8390477|uniprotkb:Q6AI46|uniprotkb:Q5W0L2|intact:MINT-7990548|ensembl:ENSP00000356530 psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym) psi-mi:rn5a_human(display_long)|uniprotkb:RNASEL(gene name)|psi-mi:RNASEL(display_short)|uniprotkb:RNS4(gene name synonym)|uniprotkb:Ribonuclease L(gene name synonym)|uniprotkb:Ribonuclease 4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479285|imex:IM-26985-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N refseq:NP_066956.1|dip:DIP-61367N|ensembl:ENSG00000135828(gene)|ensembl:ENST00000367559(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019843"(rRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR000719(Protein kinase, core)|interpro:IPR002110(Ankyrin)|interpro:IPR010513(Ribonuclease L)|interpro:IPR011009(Protein kinase-like)|interpro:IPR020683|interpro:IPR036770|interpro:IPR038357|interpro:IPR042745|mint:Q05823|rcsb pdb:1WDY|rcsb pdb:4G8K|rcsb pdb:4G8L|rcsb pdb:4OAU|rcsb pdb:4OAV|reactome:R-HSA-8983711|reactome:R-HSA-909733 - - comment:mint|comment:"author score: 36" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606 rogid:5zeVyBXaQ84yxEU3WhFHY9Cdyns9606 rigid:uGtqxSkNfc+xCnWY8zdn41T+B2c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NWT6 uniprotkb:Q9BQE3 intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479285|imex:IM-26985-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 rigid:uGtqxSkNfc+xCnWY8zdn41T+B2c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NWT6 uniprotkb:Q71UM5 intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69 intact:EBI-355126|uniprotkb:Q9BTJ1|ensembl:ENSP00000331019 psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym) psi-mi:rs27l_human(display_long)|uniprotkb:RPS27L(gene name)|psi-mi:RPS27L(display_short)|uniprotkb:Small ribosomal subunit protein eS27-like(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479285|imex:IM-26985-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N refseq:NP_057004.1|ensembl:ENSG00000185088(gene)|ensembl:ENST00000330964(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0006412"(translation)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008494"(translation activator activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046872"(metal ion binding)|interpro:IPR000592(Ribosomal protein S27e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR023407|mint:Q71UM5|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606 rogid:OVIAlDF6dN3DxLZgQFrFl8r0Z0I9606 rigid:uGtqxSkNfc+xCnWY8zdn41T+B2c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NWT6 uniprotkb:Q05086 intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69 intact:EBI-954357|ensembl:ENSP00000497594|uniprotkb:P78355|uniprotkb:Q93066|uniprotkb:Q9UEP4|uniprotkb:Q9UEP5|uniprotkb:Q9UEP6|uniprotkb:Q9UEP7|uniprotkb:Q9UEP8|uniprotkb:Q9UEP9|uniprotkb:A8K8Z9 psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym) psi-mi:ube3a_human(display_long)|uniprotkb:E6AP ubiquitin-protein ligase(gene name synonym)|uniprotkb:Oncogenic protein-associated protein E6-AP(gene name synonym)|uniprotkb:Human papillomavirus E6-associated protein(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-54(gene name synonym)|uniprotkb:UBE3A(gene name)|psi-mi:UBE3A(display_short)|uniprotkb:E6AP(gene name synonym)|uniprotkb:EPVE6AP(gene name synonym)|uniprotkb:HPVE6A(gene name synonym)|uniprotkb:HECT-type ubiquitin transferase E3A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479285|imex:IM-26985-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060736"(prostate gland growth)|go:"GO:0061002"(negative regulation of dendritic spine morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061743"(motor learning)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1905528"(positive regulation of Golgi lumen acidification)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:2000058"(regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR000569(HECT)|interpro:IPR017134(Ubiquitin-protein ligase E6-AP)|interpro:IPR032353|interpro:IPR035983|interpro:IPR042556|mint:Q05086|rcsb pdb:1C4Z|rcsb pdb:1D5F|rcsb pdb:1EQX|rcsb pdb:2KR1|rcsb pdb:4GIZ|rcsb pdb:4XR8|rcsb pdb:6SJV|rcsb pdb:6SLM|rcsb pdb:6TGK|rcsb pdb:6U19|reactome:R-HSA-983168|ensembl:ENSG00000114062(gene)|ensembl:ENST00000650110(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007420"(brain development)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032570"(response to progesterone)|go:"GO:0035037"(sperm entry)|go:"GO:0035641"(locomotory exploration behavior)|go:"GO:0042220"(response to cocaine)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048511"(rhythmic process)|refseq:NP_000453.2|refseq:NP_570853.1|refseq:NP_570854.1|refseq:XP_016878033.1|refseq:XP_016878034.1|refseq:XP_011520296.1|refseq:XP_011520297.1|refseq:XP_016878035.1|refseq:XP_016878036.1|refseq:XP_016878037.1|refseq:XP_016878038.1|refseq:XP_016878039.1|dip:DIP-6002N|refseq:XP_005268324.1|refseq:XP_005268325.1|refseq:XP_005268326.1|refseq:XP_005268327.1|refseq:XP_005268328.1|refseq:XP_006720738.1|refseq:XP_006720739.1|refseq:XP_016878040.1|refseq:XP_016878041.1|refseq:XP_016878042.1|refseq:XP_016878043.1|refseq:XP_016878044.1 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606 rogid:w9T67+NDlHSd1tR+FgcX3LI1zpQ9606 rigid:uGtqxSkNfc+xCnWY8zdn41T+B2c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NWT6 uniprotkb:P50502 intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69 intact:EBI-357285|ensembl:ENSP00000216218|uniprotkb:O14999|uniprotkb:Q2TU77 psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym) psi-mi:f10a1_human(display_long)|uniprotkb:ST13(gene name)|psi-mi:ST13(display_short)|uniprotkb:HIP(gene name synonym)|uniprotkb:SNC6(gene name synonym)|uniprotkb:AAG2(gene name synonym)|uniprotkb:Aging-associated protein 2(gene name synonym)|uniprotkb:FAM10A1(gene name synonym)|uniprotkb:Suppression of tumorigenicity 13 protein(gene name synonym)|uniprotkb:Putative tumor suppressor ST13(gene name synonym)|uniprotkb:Protein FAM10A1(gene name synonym)|uniprotkb:Progesterone receptor-associated p48 protein(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-33(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479285|imex:IM-26985-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N ensembl:ENSG00000100380(gene)|ensembl:ENST00000216218(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0009617"(response to bacterium)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0061084"(negative regulation of protein refolding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR034649|interpro:IPR041243|mint:P50502|rcsb pdb:1UZS|reactome:R-HSA-3371453|refseq:NP_003923.2 - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606 rogid:yqG5t4Kuj7ZzfNwlJzGZYscKiM89606 rigid:uGtqxSkNfc+xCnWY8zdn41T+B2c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NWT6 uniprotkb:Q9Y6H1 intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69 intact:EBI-2321769|uniprotkb:Q498C3|uniprotkb:Q6NZ50|ensembl:ENSP00000378812 psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym) psi-mi:chch2_human(display_long)|uniprotkb:CHCHD2(gene name)|psi-mi:CHCHD2(display_short)|uniprotkb:C7orf17(gene name synonym)|uniprotkb:HCV NS2 trans-regulated protein(gene name synonym)|uniprotkb:Aging-associated gene 10 protein(gene name synonym)|uniprotkb:AAG10(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479285|imex:IM-26985-95 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N refseq:NP_057223.1|ensembl:ENSG00000106153(gene)|ensembl:ENST00000395422(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900037"(regulation of cellular response to hypoxia)|go:"GO:1905448"(positive regulation of mitochondrial ATP synthesis coupled electron transport)|interpro:IPR010625(CHCH)|mint:Q9Y6H1|reactome:R-HSA-1268020 - - comment:"author score: 28" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606 rogid:fdx3lE51+yZ1k3uwh8/LDKJC+CQ9606 rigid:uGtqxSkNfc+xCnWY8zdn41T+B2c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94992 uniprotkb:Q8WXF1 intact:EBI-2832510|uniprotkb:B2R8Y5|ensembl:ENSP00000328773 intact:EBI-1392258|uniprotkb:Q5JTQ3|uniprotkb:Q8NCZ9|uniprotkb:Q8WXE8|uniprotkb:Q9NV36|ensembl:ENSP00000343966|ensembl:ENSP00000481916 psi-mi:hexi1_human(display_long)|uniprotkb:HEXIM1(gene name)|psi-mi:HEXIM1(display_short)|uniprotkb:CLP1(gene name synonym)|uniprotkb:EDG1(gene name synonym)|uniprotkb:HIS1(gene name synonym)|uniprotkb:MAQ1(gene name synonym)|uniprotkb:Cardiac lineage protein 1(gene name synonym)|uniprotkb:Estrogen down-regulated gene 1 protein(gene name synonym)|uniprotkb:Hexamethylene bis-acetamide-inducible protein 1(gene name synonym)|uniprotkb:Menage a quatre protein 1(gene name synonym) psi-mi:pspc1_human(display_long)|uniprotkb:PSPC1(gene name)|psi-mi:PSPC1(display_short)|uniprotkb:PSP1(gene name synonym)|uniprotkb:Paraspeckle protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479174|imex:IM-26985-547 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186834(gene)|ensembl:ENST00000332499(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0017069"(snRNA binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|interpro:IPR024872|mint:O94992|rcsb pdb:3S9G|rcsb pdb:2GD7|refseq:NP_006451.1|dip:DIP-46463N refseq:XP_006719907.1|refseq:NP_001035879.1|dip:DIP-39028N|refseq:XP_016876139.1|ensembl:ENSG00000121390(gene)|ensembl:ENST00000338910(transcript)|ensembl:ENST00000619300(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034522|interpro:IPR034523|interpro:IPR035979|mint:Q8WXF1|rcsb pdb:3SDE|rcsb pdb:5IFN|rcsb pdb:5WPA - - comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nnIXgp4JwA+gwrJU9DjLUW2HhtU9606 rogid:voQ5zJMl7FYato9iDkUYfzZ3q/k9606 rigid:7+vUIxPdpnBks7GeiP1ApkaO86M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94992 uniprotkb:P48730 intact:EBI-2832510|uniprotkb:B2R8Y5|ensembl:ENSP00000328773 intact:EBI-751621|uniprotkb:Q96KZ6|uniprotkb:Q9BTN5|uniprotkb:A2I2P2|ensembl:ENSP00000324464 psi-mi:hexi1_human(display_long)|uniprotkb:HEXIM1(gene name)|psi-mi:HEXIM1(display_short)|uniprotkb:CLP1(gene name synonym)|uniprotkb:EDG1(gene name synonym)|uniprotkb:HIS1(gene name synonym)|uniprotkb:MAQ1(gene name synonym)|uniprotkb:Cardiac lineage protein 1(gene name synonym)|uniprotkb:Estrogen down-regulated gene 1 protein(gene name synonym)|uniprotkb:Hexamethylene bis-acetamide-inducible protein 1(gene name synonym)|uniprotkb:Menage a quatre protein 1(gene name synonym) psi-mi:kc1d_human(display_long)|uniprotkb:CSNK1D(gene name)|psi-mi:CSNK1D(display_short)|uniprotkb:HCKID(gene name synonym)|uniprotkb:Tau-protein kinase CSNK1D(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479174|imex:IM-26985-547 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186834(gene)|ensembl:ENST00000332499(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0017069"(snRNA binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|interpro:IPR024872|mint:O94992|rcsb pdb:3S9G|rcsb pdb:2GD7|refseq:NP_006451.1|dip:DIP-46463N refseq:NP_001884.2|refseq:NP_620693.1|dip:DIP-39735N|ensembl:ENSG00000141551(gene)|ensembl:ENST00000314028(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043005"(neuron projection)|go:"GO:0045296"(cadherin binding)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905426"(positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000052"(positive regulation of non-canonical Wnt signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P48730|rcsb pdb:3UYS|rcsb pdb:3UYT|rcsb pdb:3UZP|rcsb pdb:4HGT|rcsb pdb:4HNF|rcsb pdb:4KB8|rcsb pdb:4KBA|rcsb pdb:4KBC|rcsb pdb:4KBK|rcsb pdb:4TN6|rcsb pdb:4TW9|rcsb pdb:4TWC|rcsb pdb:5IH4|rcsb pdb:5IH5|rcsb pdb:5IH6|rcsb pdb:5MQV|rcsb pdb:5OKT|rcsb pdb:5W4W|rcsb pdb:6F1W|rcsb pdb:6F26|rcsb pdb:6GZM|rcsb pdb:6HMP|rcsb pdb:6HMR|rcsb pdb:6PXN|rcsb pdb:6PXO|rcsb pdb:6PXP|rcsb pdb:6RCG|rcsb pdb:6RCH|rcsb pdb:6RU6|rcsb pdb:6RU7|rcsb pdb:6RU8|reactome:R-HSA-204005|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-400253|reactome:R-HSA-5620912|reactome:R-HSA-6791226|reactome:R-HSA-8854518 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nnIXgp4JwA+gwrJU9DjLUW2HhtU9606 rogid:Rz5aON17Bfduv29izmgHa/FR1/49606 rigid:7+vUIxPdpnBks7GeiP1ApkaO86M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94992 uniprotkb:P02545 intact:EBI-2832510|uniprotkb:B2R8Y5|ensembl:ENSP00000328773 intact:EBI-351935|uniprotkb:B4DI32|uniprotkb:E7EUI9|uniprotkb:P02546|uniprotkb:Q969I8|uniprotkb:Q96JA2|uniprotkb:D6RAQ3|uniprotkb:Q5I6Y4|uniprotkb:Q5I6Y6|uniprotkb:Q6UYC3|uniprotkb:Q5TCJ2|uniprotkb:Q5TCJ3|uniprotkb:D3DVB0|intact:EBI-28988787|ensembl:ENSP00000355292|ensembl:ENSP00000357283|ensembl:ENSP00000502256|ensembl:ENSP00000506771 psi-mi:hexi1_human(display_long)|uniprotkb:HEXIM1(gene name)|psi-mi:HEXIM1(display_short)|uniprotkb:CLP1(gene name synonym)|uniprotkb:EDG1(gene name synonym)|uniprotkb:HIS1(gene name synonym)|uniprotkb:MAQ1(gene name synonym)|uniprotkb:Cardiac lineage protein 1(gene name synonym)|uniprotkb:Estrogen down-regulated gene 1 protein(gene name synonym)|uniprotkb:Hexamethylene bis-acetamide-inducible protein 1(gene name synonym)|uniprotkb:Menage a quatre protein 1(gene name synonym) psi-mi:lmna_human(display_long)|uniprotkb:LMNA(gene name)|psi-mi:LMNA(display_short)|uniprotkb:LMN1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479174|imex:IM-26985-547 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186834(gene)|ensembl:ENST00000332499(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0017069"(snRNA binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|interpro:IPR024872|mint:O94992|rcsb pdb:3S9G|rcsb pdb:2GD7|refseq:NP_006451.1|dip:DIP-46463N refseq:NP_005563.1|refseq:NP_733821.1|refseq:NP_733822.1|refseq:NP_001244303.1|refseq:NP_001269553.1|refseq:NP_001269554.1|refseq:NP_001269555.1|ensembl:ENSG00000160789(gene)|ensembl:ENST00000361308(transcript)|ensembl:ENST00000368300(transcript)|ensembl:ENST00000675939(transcript)|ensembl:ENST00000683032(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005638"(lamin filament)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007517"(muscle organ development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072201"(negative regulation of mesenchymal cell proliferation)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1990683"(DNA double-strand break attachment to nuclear envelope)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|mint:P02545|rcsb pdb:1IFR|rcsb pdb:1IVT|rcsb pdb:1X8Y|rcsb pdb:2XV5|rcsb pdb:2YPT|rcsb pdb:3GEF|rcsb pdb:3V4Q|rcsb pdb:3V4W|rcsb pdb:3V5B|rcsb pdb:6GHD|rcsb pdb:6JLB|rcsb pdb:6RPR|rcsb pdb:6SNZ|rcsb pdb:6YF5|rcsb pdb:6YJD|reactome:R-HSA-1221632|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-352238|reactome:R-HSA-381038|reactome:R-HSA-4419969|reactome:R-HSA-6802952|reactome:R-HSA-8862803|ensembl:ENSP00000503633|ensembl:ENST00000682650|ensembl:ENSP00000506904|ensembl:ENST00000677389|ensembl:ENSP00000506771|ensembl:ENSP00000355292|ensembl:ENST00000368299|ensembl:ENSP00000357282|ensembl:ENSP00000357283|ensembl:ENST00000368301|ensembl:ENSP00000357284|ensembl:ENST00000448611|ensembl:ENSP00000395597|ensembl:ENST00000473598|ensembl:ENSP00000421821|ensembl:ENSP00000502256|ensembl:ENST00000676385|ensembl:ENSP00000502091|dip:DIP-32948N|dip:DIP-58162N - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nnIXgp4JwA+gwrJU9DjLUW2HhtU9606 rogid:OS/QDFLGOD2PElQ6mCpBtk6xh/09606 rigid:7+vUIxPdpnBks7GeiP1ApkaO86M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94992 uniprotkb:Q6P1X5 intact:EBI-2832510|uniprotkb:B2R8Y5|ensembl:ENSP00000328773 intact:EBI-1560063|uniprotkb:O43487|uniprotkb:O43604|uniprotkb:O60668|uniprotkb:Q86WW7|uniprotkb:Q8IWK4|uniprotkb:B2RE82|ensembl:ENSP00000367406 psi-mi:hexi1_human(display_long)|uniprotkb:HEXIM1(gene name)|psi-mi:HEXIM1(display_short)|uniprotkb:CLP1(gene name synonym)|uniprotkb:EDG1(gene name synonym)|uniprotkb:HIS1(gene name synonym)|uniprotkb:MAQ1(gene name synonym)|uniprotkb:Cardiac lineage protein 1(gene name synonym)|uniprotkb:Estrogen down-regulated gene 1 protein(gene name synonym)|uniprotkb:Hexamethylene bis-acetamide-inducible protein 1(gene name synonym)|uniprotkb:Menage a quatre protein 1(gene name synonym) psi-mi:taf2_human(display_long)|uniprotkb:Transcription initiation factor TFIID 150 kDa subunit(gene name synonym)|uniprotkb:TBP-associated factor 150 kDa(gene name synonym)|uniprotkb:150 kDa cofactor of initiator function(gene name synonym)|uniprotkb:RNA polymerase II TBP-associated factor subunit B(gene name synonym)|uniprotkb:TAF2(gene name)|psi-mi:TAF2(display_short)|uniprotkb:CIF150(gene name synonym)|uniprotkb:TAF2B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479174|imex:IM-26985-547 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186834(gene)|ensembl:ENST00000332499(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0017069"(snRNA binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|interpro:IPR024872|mint:O94992|rcsb pdb:3S9G|rcsb pdb:2GD7|refseq:NP_006451.1|dip:DIP-46463N refseq:NP_003175.1|dip:DIP-38921N|ensembl:ENSG00000064313(gene)|ensembl:ENST00000378164(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0014070"(response to organic cyclic compound)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0033276"(transcription factor TFTC complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027268|interpro:IPR037813|interpro:IPR042097|mint:Q6P1X5|rcsb pdb:5FUR|rcsb pdb:6MZC|rcsb pdb:6MZL|rcsb pdb:6MZM|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7EGD|rcsb pdb:7EGE|rcsb pdb:7EGH|rcsb pdb:7EGI|rcsb pdb:7EGJ|rcsb pdb:7ENA|rcsb pdb:7ENC|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nnIXgp4JwA+gwrJU9DjLUW2HhtU9606 rogid:3MPkpqVRwuY2SiUxjQkcRFlq1RM9606 rigid:7+vUIxPdpnBks7GeiP1ApkaO86M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94992 uniprotkb:Q14247 intact:EBI-2832510|uniprotkb:B2R8Y5|ensembl:ENSP00000328773 intact:EBI-351886|intact:EBI-3959948|ensembl:ENSP00000301843|ensembl:ENSP00000500756|uniprotkb:Q8N707|uniprotkb:Q96H99 psi-mi:hexi1_human(display_long)|uniprotkb:HEXIM1(gene name)|psi-mi:HEXIM1(display_short)|uniprotkb:CLP1(gene name synonym)|uniprotkb:EDG1(gene name synonym)|uniprotkb:HIS1(gene name synonym)|uniprotkb:MAQ1(gene name synonym)|uniprotkb:Cardiac lineage protein 1(gene name synonym)|uniprotkb:Estrogen down-regulated gene 1 protein(gene name synonym)|uniprotkb:Hexamethylene bis-acetamide-inducible protein 1(gene name synonym)|uniprotkb:Menage a quatre protein 1(gene name synonym) psi-mi:src8_human(display_long)|uniprotkb:CTTN(gene name)|psi-mi:CTTN(display_short)|uniprotkb:EMS1(gene name synonym)|uniprotkb:Amplaxin(gene name synonym)|uniprotkb:Oncogene EMS1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479174|imex:IM-26985-547 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186834(gene)|ensembl:ENST00000332499(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0017069"(snRNA binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|interpro:IPR024872|mint:O94992|rcsb pdb:3S9G|rcsb pdb:2GD7|refseq:NP_006451.1|dip:DIP-46463N refseq:NP_005222.2|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097581"(lamellipodium organization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR015503(Cortactin)|interpro:IPR035716|interpro:IPR036028|mint:Q14247|rcsb pdb:1X69|rcsb pdb:2D1X|reactome:R-HSA-5627123|reactome:R-HSA-8856828|ensembl:ENSG00000085733(gene)|ensembl:ENSG00000288401(gene)|ensembl:ENST00000301843(transcript)|ensembl:ENST00000671805(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|refseq:NP_001171669.1|refseq:NP_612632.1|dip:DIP-33190N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nnIXgp4JwA+gwrJU9DjLUW2HhtU9606 rogid:uzhAnL5Fu9Mgg9/LWeNiaYIwNVU9606 rigid:7+vUIxPdpnBks7GeiP1ApkaO86M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94992 uniprotkb:Q8WUA2 intact:EBI-2832510|uniprotkb:B2R8Y5|ensembl:ENSP00000328773 intact:EBI-2513119|ensembl:ENSP00000253329|uniprotkb:B2RD34|uniprotkb:Q7Z3Q5 psi-mi:hexi1_human(display_long)|uniprotkb:HEXIM1(gene name)|psi-mi:HEXIM1(display_short)|uniprotkb:CLP1(gene name synonym)|uniprotkb:EDG1(gene name synonym)|uniprotkb:HIS1(gene name synonym)|uniprotkb:MAQ1(gene name synonym)|uniprotkb:Cardiac lineage protein 1(gene name synonym)|uniprotkb:Estrogen down-regulated gene 1 protein(gene name synonym)|uniprotkb:Hexamethylene bis-acetamide-inducible protein 1(gene name synonym)|uniprotkb:Menage a quatre protein 1(gene name synonym) psi-mi:ppil4_human(display_long)|uniprotkb:PPIL4(gene name)|psi-mi:PPIL4(display_short)|uniprotkb:Cyclophilin-like protein PPIL4(gene name synonym)|uniprotkb:Rotamase PPIL4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479174|imex:IM-26985-547 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186834(gene)|ensembl:ENST00000332499(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0017069"(snRNA binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|interpro:IPR024872|mint:O94992|rcsb pdb:3S9G|rcsb pdb:2GD7|refseq:NP_006451.1|dip:DIP-46463N go:"GO:1901407"(regulation of phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029000|interpro:IPR035538|interpro:IPR035542|interpro:IPR035979|mint:Q8WUA2|reactome:R-HSA-72163|go:"GO:0005829"(cytosol)|ensembl:ENSG00000131013(gene)|ensembl:ENST00000253329(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|refseq:NP_624311.1 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nnIXgp4JwA+gwrJU9DjLUW2HhtU9606 rogid:kxM/VRcLUG5M5FAlHuuAKRBKrd89606 rigid:7+vUIxPdpnBks7GeiP1ApkaO86M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94992 uniprotkb:P62917 intact:EBI-2832510|uniprotkb:B2R8Y5|ensembl:ENSP00000328773 intact:EBI-438527|ensembl:ENSP00000262584|ensembl:ENSP00000378378|ensembl:ENSP00000433464|uniprotkb:P25120|uniprotkb:Q567Q7|uniprotkb:Q969V7|uniprotkb:Q9BWQ9|uniprotkb:A8K094|uniprotkb:D3DWN2 psi-mi:hexi1_human(display_long)|uniprotkb:HEXIM1(gene name)|psi-mi:HEXIM1(display_short)|uniprotkb:CLP1(gene name synonym)|uniprotkb:EDG1(gene name synonym)|uniprotkb:HIS1(gene name synonym)|uniprotkb:MAQ1(gene name synonym)|uniprotkb:Cardiac lineage protein 1(gene name synonym)|uniprotkb:Estrogen down-regulated gene 1 protein(gene name synonym)|uniprotkb:Hexamethylene bis-acetamide-inducible protein 1(gene name synonym)|uniprotkb:Menage a quatre protein 1(gene name synonym) psi-mi:rl8_human(display_long)|uniprotkb:RPL8(gene name)|psi-mi:RPL8(display_short)|uniprotkb:Large ribosomal subunit protein uL2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479174|imex:IM-26985-547 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186834(gene)|ensembl:ENST00000332499(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0017069"(snRNA binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|interpro:IPR024872|mint:O94992|rcsb pdb:3S9G|rcsb pdb:2GD7|refseq:NP_006451.1|dip:DIP-46463N rcsb pdb:4CCN|rcsb pdb:4CCO|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:4Y3O|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000161016(gene)|ensembl:ENST00000262584(transcript)|ensembl:ENST00000394920(transcript)|ensembl:ENST00000528957(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0098794"(postsynapse)|interpro:IPR002171(Ribosomal protein L2)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR014726(Ribosomal protein L2, domain 3)|interpro:IPR022666|interpro:IPR022669|interpro:IPR022671|interpro:IPR023672|mint:P62917|rcsb pdb:4CCM|refseq:NP_000964.1|refseq:NP_150644.1|refseq:NP_001304700.1|refseq:NP_001304711.1|dip:DIP-37967N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nnIXgp4JwA+gwrJU9DjLUW2HhtU9606 rogid:+b/ORzdCy/nqFLsKRV9VhIZgdjg9606 rigid:7+vUIxPdpnBks7GeiP1ApkaO86M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94992 uniprotkb:O94842 intact:EBI-2832510|uniprotkb:B2R8Y5|ensembl:ENSP00000328773 intact:EBI-948613|ensembl:ENSP00000393080|ensembl:ENSP00000477868|intact:EBI-10965337|uniprotkb:B4DPY8|uniprotkb:E7EV69|uniprotkb:B4DSM0 psi-mi:hexi1_human(display_long)|uniprotkb:HEXIM1(gene name)|psi-mi:HEXIM1(display_short)|uniprotkb:CLP1(gene name synonym)|uniprotkb:EDG1(gene name synonym)|uniprotkb:HIS1(gene name synonym)|uniprotkb:MAQ1(gene name synonym)|uniprotkb:Cardiac lineage protein 1(gene name synonym)|uniprotkb:Estrogen down-regulated gene 1 protein(gene name synonym)|uniprotkb:Hexamethylene bis-acetamide-inducible protein 1(gene name synonym)|uniprotkb:Menage a quatre protein 1(gene name synonym) psi-mi:tox4_human(display_long)|uniprotkb:Epidermal Langerhans cell protein LCP1(gene name synonym)|uniprotkb:TOX4(gene name)|psi-mi:TOX4(display_short)|uniprotkb:KIAA0737(gene name synonym)|uniprotkb:C14orf92(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479174|imex:IM-26985-547 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186834(gene)|ensembl:ENST00000332499(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0017069"(snRNA binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|interpro:IPR024872|mint:O94992|rcsb pdb:3S9G|rcsb pdb:2GD7|refseq:NP_006451.1|dip:DIP-46463N ensembl:ENSG00000092203(gene)|ensembl:ENST00000448790(transcript)|ensembl:ENST00000613569(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|interpro:IPR037985|mint:O94842|refseq:NP_055643.1|refseq:NP_001290452.1 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nnIXgp4JwA+gwrJU9DjLUW2HhtU9606 rogid:tiW0mcDNOr9TsvNLVZ+f36eiNpY9606 rigid:7+vUIxPdpnBks7GeiP1ApkaO86M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94992 uniprotkb:Q7L2J0 intact:EBI-2832510|uniprotkb:B2R8Y5|ensembl:ENSP00000328773 intact:EBI-2371983|uniprotkb:Q9NPD4|uniprotkb:B3KP86|uniprotkb:D6W5V7|ensembl:ENSP00000308546 psi-mi:hexi1_human(display_long)|uniprotkb:HEXIM1(gene name)|psi-mi:HEXIM1(display_short)|uniprotkb:CLP1(gene name synonym)|uniprotkb:EDG1(gene name synonym)|uniprotkb:HIS1(gene name synonym)|uniprotkb:MAQ1(gene name synonym)|uniprotkb:Cardiac lineage protein 1(gene name synonym)|uniprotkb:Estrogen down-regulated gene 1 protein(gene name synonym)|uniprotkb:Hexamethylene bis-acetamide-inducible protein 1(gene name synonym)|uniprotkb:Menage a quatre protein 1(gene name synonym) psi-mi:mepce_human(display_long)|uniprotkb:MEPCE(gene name)|psi-mi:MEPCE(display_short)|uniprotkb:BCDIN3(gene name synonym)|uniprotkb:Bicoid-interacting protein 3 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479174|imex:IM-26985-547 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186834(gene)|ensembl:ENST00000332499(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0017069"(snRNA binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|interpro:IPR024872|mint:O94992|rcsb pdb:3S9G|rcsb pdb:2GD7|refseq:NP_006451.1|dip:DIP-46463N refseq:XP_011514712.1|refseq:NP_001181919.1|refseq:NP_001181920.1|refseq:NP_001181921.1|refseq:NP_062552.2|ensembl:ENSG00000146834(gene)|ensembl:ENST00000310512(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001510"(RNA methylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0008171"(O-methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0016073"(snRNA metabolic process)|go:"GO:0017069"(snRNA binding)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0040031"(snRNA modification)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1905382"(positive regulation of snRNA transcription by RNA polymerase II)|go:"GO:1990276"(RNA 5'-methyltransferase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR010675(Bicoid-interacting 3)|interpro:IPR024160|interpro:IPR025714|interpro:IPR029063|interpro:IPR039772|mint:Q7L2J0|rcsb pdb:5UNA|rcsb pdb:6DCB|rcsb pdb:6DCC - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nnIXgp4JwA+gwrJU9DjLUW2HhtU9606 rogid:VGhJoO3FD7nsJPVSBsKuKsPJzEM9606 rigid:7+vUIxPdpnBks7GeiP1ApkaO86M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94992 uniprotkb:P39019 intact:EBI-2832510|uniprotkb:B2R8Y5|ensembl:ENSP00000328773 intact:EBI-354451|ensembl:ENSP00000469228|ensembl:ENSP00000470004|ensembl:ENSP00000470972 psi-mi:hexi1_human(display_long)|uniprotkb:HEXIM1(gene name)|psi-mi:HEXIM1(display_short)|uniprotkb:CLP1(gene name synonym)|uniprotkb:EDG1(gene name synonym)|uniprotkb:HIS1(gene name synonym)|uniprotkb:MAQ1(gene name synonym)|uniprotkb:Cardiac lineage protein 1(gene name synonym)|uniprotkb:Estrogen down-regulated gene 1 protein(gene name synonym)|uniprotkb:Hexamethylene bis-acetamide-inducible protein 1(gene name synonym)|uniprotkb:Menage a quatre protein 1(gene name synonym) psi-mi:rs19_human(display_long)|uniprotkb:RPS19(gene name)|psi-mi:RPS19(display_short)|uniprotkb:Small ribosomal subunit protein eS19(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479174|imex:IM-26985-547 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186834(gene)|ensembl:ENST00000332499(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0017069"(snRNA binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|interpro:IPR024872|mint:O94992|rcsb pdb:3S9G|rcsb pdb:2GD7|refseq:NP_006451.1|dip:DIP-46463N refseq:NP_001013.1|ensembl:ENSG00000105372(gene)|ensembl:ENST00000593863(transcript)|ensembl:ENST00000598742(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003723"(RNA binding)|ensembl:ENST00000600467(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0007000"(nucleolus organization)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0060265"(positive regulation of respiratory burst involved in inflammatory response)|go:"GO:0060266"(negative regulation of respiratory burst involved in inflammatory response)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001266(Ribosomal protein S19e)|interpro:IPR018277|interpro:IPR036388|interpro:IPR036390|mint:P39019|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001308412.1|refseq:NP_001308413.1 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nnIXgp4JwA+gwrJU9DjLUW2HhtU9606 rogid:3YqdJJJG+2nqoBf3PLu1fs7pVkY9606 rigid:7+vUIxPdpnBks7GeiP1ApkaO86M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94992 uniprotkb:Q4VCS5 intact:EBI-2832510|uniprotkb:B2R8Y5|ensembl:ENSP00000328773 intact:EBI-2511319|ensembl:ENSP00000361027|uniprotkb:Q504X5|uniprotkb:Q9UPT1|uniprotkb:Q9HD27 psi-mi:hexi1_human(display_long)|uniprotkb:HEXIM1(gene name)|psi-mi:HEXIM1(display_short)|uniprotkb:CLP1(gene name synonym)|uniprotkb:EDG1(gene name synonym)|uniprotkb:HIS1(gene name synonym)|uniprotkb:MAQ1(gene name synonym)|uniprotkb:Cardiac lineage protein 1(gene name synonym)|uniprotkb:Estrogen down-regulated gene 1 protein(gene name synonym)|uniprotkb:Hexamethylene bis-acetamide-inducible protein 1(gene name synonym)|uniprotkb:Menage a quatre protein 1(gene name synonym) psi-mi:amot_human(display_long)|uniprotkb:AMOT(gene name)|psi-mi:AMOT(display_short)|uniprotkb:KIAA1071(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479174|imex:IM-26985-547 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186834(gene)|ensembl:ENST00000332499(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0017069"(snRNA binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|interpro:IPR024872|mint:O94992|rcsb pdb:3S9G|rcsb pdb:2GD7|refseq:NP_006451.1|dip:DIP-46463N ensembl:ENSG00000126016(gene)|ensembl:ENST00000371959(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006935"(chemotaxis)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035329"(hippo signaling)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q4VCS5|rcsb pdb:6JJX|reactome:R-HSA-2028269|refseq:XP_011529177.1|refseq:NP_001106962.1|refseq:NP_573572.1|refseq:XP_005262144.1|refseq:XP_005262147.1|refseq:XP_016884778.1|dip:DIP-53711N - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nnIXgp4JwA+gwrJU9DjLUW2HhtU9606 rogid:5O9K+GgX1s0Hn5optTeKPOs+X1s9606 rigid:7+vUIxPdpnBks7GeiP1ApkaO86M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94992 uniprotkb:P50750 intact:EBI-2832510|uniprotkb:B2R8Y5|ensembl:ENSP00000328773 intact:EBI-1383449|uniprotkb:Q5JU24|uniprotkb:Q5JU25|uniprotkb:Q5U006|uniprotkb:Q96TF1|ensembl:ENSP00000362361 psi-mi:hexi1_human(display_long)|uniprotkb:HEXIM1(gene name)|psi-mi:HEXIM1(display_short)|uniprotkb:CLP1(gene name synonym)|uniprotkb:EDG1(gene name synonym)|uniprotkb:HIS1(gene name synonym)|uniprotkb:MAQ1(gene name synonym)|uniprotkb:Cardiac lineage protein 1(gene name synonym)|uniprotkb:Estrogen down-regulated gene 1 protein(gene name synonym)|uniprotkb:Hexamethylene bis-acetamide-inducible protein 1(gene name synonym)|uniprotkb:Menage a quatre protein 1(gene name synonym) psi-mi:cdk9_human(display_long)|uniprotkb:CDK9(gene name)|psi-mi:CDK9(display_short)|uniprotkb:CDC2L4(gene name synonym)|uniprotkb:Cell division protein kinase 9(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PITALRE(gene name synonym)|uniprotkb:Cell division cycle 2-like protein kinase 4(gene name synonym)|uniprotkb:C-2K(gene name synonym)|uniprotkb:TAK(gene name synonym)|uniprotkb:Tat-associated kinase complex catalytic subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479174|imex:IM-26985-547 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186834(gene)|ensembl:ENST00000332499(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0017069"(snRNA binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|interpro:IPR024872|mint:O94992|rcsb pdb:3S9G|rcsb pdb:2GD7|refseq:NP_006451.1|dip:DIP-46463N refseq:NP_001252.1|dip:DIP-29016N|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000136807(gene)|ensembl:ENST00000373264(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P50750|rcsb pdb:1PF6|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nnIXgp4JwA+gwrJU9DjLUW2HhtU9606 rogid:XSEmM4b5tp/WCJCJxnQYyP0stvM9606 rigid:7+vUIxPdpnBks7GeiP1ApkaO86M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94992 uniprotkb:Q99575 intact:EBI-2832510|uniprotkb:B2R8Y5|ensembl:ENSP00000328773 intact:EBI-366741|uniprotkb:Q15037|uniprotkb:A8K5W9|intact:EBI-2560204|ensembl:ENSP00000339529|ensembl:ENSP00000385787 psi-mi:hexi1_human(display_long)|uniprotkb:HEXIM1(gene name)|psi-mi:HEXIM1(display_short)|uniprotkb:CLP1(gene name synonym)|uniprotkb:EDG1(gene name synonym)|uniprotkb:HIS1(gene name synonym)|uniprotkb:MAQ1(gene name synonym)|uniprotkb:Cardiac lineage protein 1(gene name synonym)|uniprotkb:Estrogen down-regulated gene 1 protein(gene name synonym)|uniprotkb:Hexamethylene bis-acetamide-inducible protein 1(gene name synonym)|uniprotkb:Menage a quatre protein 1(gene name synonym) psi-mi:pop1_human(display_long)|uniprotkb:POP1(gene name)|psi-mi:POP1(display_short)|uniprotkb:KIAA0061(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479174|imex:IM-26985-547 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186834(gene)|ensembl:ENST00000332499(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0017069"(snRNA binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|interpro:IPR024872|mint:O94992|rcsb pdb:3S9G|rcsb pdb:2GD7|refseq:NP_006451.1|dip:DIP-46463N refseq:NP_001139332.1|refseq:NP_001139333.1|refseq:NP_055844.2|ensembl:ENSG00000104356(gene)|ensembl:ENST00000349693(transcript)|ensembl:ENST00000401707(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008033"(tRNA processing)|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR009723(Ribonuclease P/MRP, POP1)|interpro:IPR012590(POPLD)|interpro:IPR039182|mint:Q99575|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nnIXgp4JwA+gwrJU9DjLUW2HhtU9606 rogid:XJxSr17TfVuetXKgpQPjs2QKMV49606 rigid:7+vUIxPdpnBks7GeiP1ApkaO86M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94992 uniprotkb:P51608 intact:EBI-2832510|uniprotkb:B2R8Y5|ensembl:ENSP00000328773 intact:EBI-1189067|uniprotkb:O15233|uniprotkb:Q6QHH9|uniprotkb:Q7Z384|ensembl:ENSP00000301948 psi-mi:hexi1_human(display_long)|uniprotkb:HEXIM1(gene name)|psi-mi:HEXIM1(display_short)|uniprotkb:CLP1(gene name synonym)|uniprotkb:EDG1(gene name synonym)|uniprotkb:HIS1(gene name synonym)|uniprotkb:MAQ1(gene name synonym)|uniprotkb:Cardiac lineage protein 1(gene name synonym)|uniprotkb:Estrogen down-regulated gene 1 protein(gene name synonym)|uniprotkb:Hexamethylene bis-acetamide-inducible protein 1(gene name synonym)|uniprotkb:Menage a quatre protein 1(gene name synonym) psi-mi:mecp2_human(display_long)|uniprotkb:MECP2(gene name)|psi-mi:MECP2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479174|imex:IM-26985-547 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186834(gene)|ensembl:ENST00000332499(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0017069"(snRNA binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|interpro:IPR024872|mint:O94992|rcsb pdb:3S9G|rcsb pdb:2GD7|refseq:NP_006451.1|dip:DIP-46463N refseq:NP_001104262.1|refseq:NP_004983.1|refseq:NP_001303266.1|ensembl:ENSG00000169057(gene)|ensembl:ENST00000303391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0001662"(behavioral fear response)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001964"(startle response)|go:"GO:0001976"(nervous system process involved in regulation of systemic arterial blood pressure)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006020"(inositol metabolic process)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006576"(cellular biogenic amine metabolic process)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007416"(synapse assembly)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0007616"(long-term memory)|go:"GO:0008104"(protein localization)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016358"(dendrite development)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016571"(histone methylation)|go:"GO:0016573"(histone acetylation)|go:"GO:0019230"(proprioception)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021591"(ventricular system development)|go:"GO:0032048"(cardiolipin metabolic process)|go:"GO:0035176"(social behavior)|go:"GO:0035197"(siRNA binding)|go:"GO:0042551"(neuron maturation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051151"(negative regulation of smooth muscle cell differentiation)|go:"GO:0051707"(response to other organism)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0098794"(postsynapse)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|go:"GO:1905643"(positive regulation of DNA methylation)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000820"(negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR017353(Methyl-CpG binding protein MeCP2)|mint:P51608|rcsb pdb:1QK9|rcsb pdb:3C2I|rcsb pdb:5BT2|rcsb pdb:6C1Y|rcsb pdb:6OGJ|rcsb pdb:6OGK|reactome:R-HSA-8986944|reactome:R-HSA-9022534|reactome:R-HSA-9022535|reactome:R-HSA-9022537|reactome:R-HSA-9022538|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9022702|reactome:R-HSA-9022707|reactome:R-HSA-9022927|dip:DIP-39983N - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nnIXgp4JwA+gwrJU9DjLUW2HhtU9606 rogid:7c5ZZAZsqV7AciGN4hzFNWJLeUk9606 rigid:7+vUIxPdpnBks7GeiP1ApkaO86M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94992 uniprotkb:Q6UXN9 intact:EBI-2832510|uniprotkb:B2R8Y5|ensembl:ENSP00000328773 intact:EBI-1176082|uniprotkb:Q8TEB2|uniprotkb:A8K5R5|intact:EBI-2562464|ensembl:ENSP00000296490 psi-mi:hexi1_human(display_long)|uniprotkb:HEXIM1(gene name)|psi-mi:HEXIM1(display_short)|uniprotkb:CLP1(gene name synonym)|uniprotkb:EDG1(gene name synonym)|uniprotkb:HIS1(gene name synonym)|uniprotkb:MAQ1(gene name synonym)|uniprotkb:Cardiac lineage protein 1(gene name synonym)|uniprotkb:Estrogen down-regulated gene 1 protein(gene name synonym)|uniprotkb:Hexamethylene bis-acetamide-inducible protein 1(gene name synonym)|uniprotkb:Menage a quatre protein 1(gene name synonym) psi-mi:wdr82_human(display_long)|uniprotkb:Protein TMEM113(gene name synonym)|uniprotkb:TMEM113(gene name synonym)|uniprotkb:WDR82(gene name)|psi-mi:WDR82(display_short)|uniprotkb:Swd2(gene name synonym)|uniprotkb:WDR82A(gene name synonym)|uniprotkb:UNQ9342/PRO34047(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479174|imex:IM-26985-547 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186834(gene)|ensembl:ENST00000332499(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0017069"(snRNA binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|interpro:IPR024872|mint:O94992|rcsb pdb:3S9G|rcsb pdb:2GD7|refseq:NP_006451.1|dip:DIP-46463N refseq:NP_079498.2|ensembl:ENSG00000164091(gene)|ensembl:ENST00000296490(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005730"(nucleolus)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|interpro:IPR037867|mint:Q6UXN9 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nnIXgp4JwA+gwrJU9DjLUW2HhtU9606 rogid:0TyKYwpTLd22Cm+ihT1+n0oo12c9606 rigid:7+vUIxPdpnBks7GeiP1ApkaO86M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94992 uniprotkb:P26196 intact:EBI-2832510|uniprotkb:B2R8Y5|ensembl:ENSP00000328773 intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754 psi-mi:hexi1_human(display_long)|uniprotkb:HEXIM1(gene name)|psi-mi:HEXIM1(display_short)|uniprotkb:CLP1(gene name synonym)|uniprotkb:EDG1(gene name synonym)|uniprotkb:HIS1(gene name synonym)|uniprotkb:MAQ1(gene name synonym)|uniprotkb:Cardiac lineage protein 1(gene name synonym)|uniprotkb:Estrogen down-regulated gene 1 protein(gene name synonym)|uniprotkb:Hexamethylene bis-acetamide-inducible protein 1(gene name synonym)|uniprotkb:Menage a quatre protein 1(gene name synonym) psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479174|imex:IM-26985-547 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186834(gene)|ensembl:ENST00000332499(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0017069"(snRNA binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|interpro:IPR024872|mint:O94992|rcsb pdb:3S9G|rcsb pdb:2GD7|refseq:NP_006451.1|dip:DIP-46463N refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nnIXgp4JwA+gwrJU9DjLUW2HhtU9606 rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606 rigid:7+vUIxPdpnBks7GeiP1ApkaO86M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94992 uniprotkb:P25490 intact:EBI-2832510|uniprotkb:B2R8Y5|ensembl:ENSP00000328773 intact:EBI-765538|uniprotkb:Q14935|ensembl:ENSP00000262238 psi-mi:hexi1_human(display_long)|uniprotkb:HEXIM1(gene name)|psi-mi:HEXIM1(display_short)|uniprotkb:CLP1(gene name synonym)|uniprotkb:EDG1(gene name synonym)|uniprotkb:HIS1(gene name synonym)|uniprotkb:MAQ1(gene name synonym)|uniprotkb:Cardiac lineage protein 1(gene name synonym)|uniprotkb:Estrogen down-regulated gene 1 protein(gene name synonym)|uniprotkb:Hexamethylene bis-acetamide-inducible protein 1(gene name synonym)|uniprotkb:Menage a quatre protein 1(gene name synonym) psi-mi:tyy1_human(display_long)|uniprotkb:Yin and yang 1(gene name synonym)|uniprotkb:Delta transcription factor(gene name synonym)|uniprotkb:NF-E1(gene name synonym)|uniprotkb:YY1(gene name)|psi-mi:YY1(display_short)|uniprotkb:INO80S(gene name synonym)|uniprotkb:INO80 complex subunit S(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479174|imex:IM-26985-547 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186834(gene)|ensembl:ENST00000332499(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0017069"(snRNA binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|interpro:IPR024872|mint:O94992|rcsb pdb:3S9G|rcsb pdb:2GD7|refseq:NP_006451.1|dip:DIP-46463N refseq:NP_003394.1|dip:DIP-150N|ensembl:ENSG00000100811(gene)|rcsb pdb:1UBD|rcsb pdb:1ZNM|rcsb pdb:4C5I|reactome:R-HSA-5617472|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8866910|reactome:R-HSA-9018519|ensembl:ENST00000262238(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006403"(RNA localization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010225"(response to UV-C)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034696"(response to prostaglandin F)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048468"(cell development)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0051276"(chromosome organization)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017114(Transcription factor yin and yang)|interpro:IPR036236|mint:P25490 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nnIXgp4JwA+gwrJU9DjLUW2HhtU9606 rogid:OncFlxfcbNZGN68Sk39CRh9oQHc9606 rigid:7+vUIxPdpnBks7GeiP1ApkaO86M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94992 uniprotkb:O43290 intact:EBI-2832510|uniprotkb:B2R8Y5|ensembl:ENSP00000328773 intact:EBI-607761|ensembl:ENSP00000310448|uniprotkb:A6NDN1|uniprotkb:Q53GB5 psi-mi:hexi1_human(display_long)|uniprotkb:HEXIM1(gene name)|psi-mi:HEXIM1(display_short)|uniprotkb:CLP1(gene name synonym)|uniprotkb:EDG1(gene name synonym)|uniprotkb:HIS1(gene name synonym)|uniprotkb:MAQ1(gene name synonym)|uniprotkb:Cardiac lineage protein 1(gene name synonym)|uniprotkb:Estrogen down-regulated gene 1 protein(gene name synonym)|uniprotkb:Hexamethylene bis-acetamide-inducible protein 1(gene name synonym)|uniprotkb:Menage a quatre protein 1(gene name synonym) psi-mi:snut1_human(display_long)|uniprotkb:U4/U6.U5 tri-snRNP-associated 110 kDa protein(gene name synonym)|uniprotkb:SART1(gene name)|psi-mi:SART1(display_short)|uniprotkb:SNU66 homolog(gene name synonym)|uniprotkb:Squamous cell carcinoma antigen recognized by T-cells 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479174|imex:IM-26985-547 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186834(gene)|ensembl:ENST00000332499(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0017069"(snRNA binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|interpro:IPR024872|mint:O94992|rcsb pdb:3S9G|rcsb pdb:2GD7|refseq:NP_006451.1|dip:DIP-46463N ensembl:ENSG00000175467(gene)|ensembl:ENST00000312397(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000481"(maturation of 5S rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0045585"(positive regulation of cytotoxic T cell differentiation)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR005011(SART-1 protein)|mint:O43290|rcsb pdb:4PYU|rcsb pdb:5O9Z|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|reactome:R-HSA-72163|refseq:NP_005137.1|dip:DIP-33360N - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nnIXgp4JwA+gwrJU9DjLUW2HhtU9606 rogid:egvWHy7UXW+MkGtGEW984yvRU9k9606 rigid:7+vUIxPdpnBks7GeiP1ApkaO86M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94992 uniprotkb:Q9H7C9 intact:EBI-2832510|uniprotkb:B2R8Y5|ensembl:ENSP00000328773 intact:EBI-10308705|uniprotkb:Q9Y6B1|uniprotkb:Q96AQ4|ensembl:ENSP00000377078|ensembl:ENSP00000431808 psi-mi:hexi1_human(display_long)|uniprotkb:HEXIM1(gene name)|psi-mi:HEXIM1(display_short)|uniprotkb:CLP1(gene name synonym)|uniprotkb:EDG1(gene name synonym)|uniprotkb:HIS1(gene name synonym)|uniprotkb:MAQ1(gene name synonym)|uniprotkb:Cardiac lineage protein 1(gene name synonym)|uniprotkb:Estrogen down-regulated gene 1 protein(gene name synonym)|uniprotkb:Hexamethylene bis-acetamide-inducible protein 1(gene name synonym)|uniprotkb:Menage a quatre protein 1(gene name synonym) psi-mi:aamdc_human(display_long)|uniprotkb:AAMDC(gene name)|psi-mi:AAMDC(display_short)|uniprotkb:Adipogenesis associated Mth938 domain-containing protein(gene name synonym)|uniprotkb:C11orf67(gene name synonym)|uniprotkb:PTD015(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479174|imex:IM-26985-547 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186834(gene)|ensembl:ENST00000332499(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0017069"(snRNA binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|interpro:IPR024872|mint:O94992|rcsb pdb:3S9G|rcsb pdb:2GD7|refseq:NP_006451.1|dip:DIP-46463N refseq:NP_001303886.1|refseq:NP_001303889.1|refseq:NP_001303890.1|refseq:NP_001303891.1|refseq:NP_078960.1|refseq:XP_011543271.1|ensembl:ENSG00000087884(gene)|ensembl:ENST00000393427(transcript)|ensembl:ENST00000526415(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0045600"(positive regulation of fat cell differentiation)|interpro:IPR007523(Protein of unknown function DUF498)|interpro:IPR034096|interpro:IPR036748|mint:Q9H7C9|rcsb pdb:2AB1|rcsb pdb:2Q4Q - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nnIXgp4JwA+gwrJU9DjLUW2HhtU9606 rogid:K1kfbdCxyGTAglEl+pDfu4NjjMs9606 rigid:7+vUIxPdpnBks7GeiP1ApkaO86M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94992 uniprotkb:Q96QC0 intact:EBI-2832510|uniprotkb:B2R8Y5|ensembl:ENSP00000328773 intact:EBI-1210346|uniprotkb:O00405|ensembl:ENSP00000365694|ensembl:ENSP00000373080|ensembl:ENSP00000389299|ensembl:ENSP00000407181|ensembl:ENSP00000407310|ensembl:ENSP00000413554|ensembl:ENSP00000416060 psi-mi:hexi1_human(display_long)|uniprotkb:HEXIM1(gene name)|psi-mi:HEXIM1(display_short)|uniprotkb:CLP1(gene name synonym)|uniprotkb:EDG1(gene name synonym)|uniprotkb:HIS1(gene name synonym)|uniprotkb:MAQ1(gene name synonym)|uniprotkb:Cardiac lineage protein 1(gene name synonym)|uniprotkb:Estrogen down-regulated gene 1 protein(gene name synonym)|uniprotkb:Hexamethylene bis-acetamide-inducible protein 1(gene name synonym)|uniprotkb:Menage a quatre protein 1(gene name synonym) psi-mi:pp1ra_human(display_long)|uniprotkb:PPP1R10(gene name)|psi-mi:PPP1R10(display_short)|uniprotkb:CAT53(gene name synonym)|uniprotkb:FB19(gene name synonym)|uniprotkb:PNUTS(gene name synonym)|uniprotkb:Phosphatase 1 nuclear targeting subunit(gene name synonym)|uniprotkb:MHC class I region proline-rich protein CAT53(gene name synonym)|uniprotkb:Protein FB19(gene name synonym)|uniprotkb:PP1-binding protein of 114 kDa(gene name synonym)|uniprotkb:p99(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479174|imex:IM-26985-547 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186834(gene)|ensembl:ENST00000332499(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0017069"(snRNA binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|interpro:IPR024872|mint:O94992|rcsb pdb:3S9G|rcsb pdb:2GD7|refseq:NP_006451.1|dip:DIP-46463N refseq:XP_011513024.1|refseq:NP_002705.2|refseq:XP_006715193.1|refseq:XP_016866484.1|dip:DIP-39343N|ensembl:ENSG00000204569(gene)|ensembl:ENSG00000206489(gene)|ensembl:ENSG00000227804(gene)|ensembl:ENSG00000230995(gene)|ensembl:ENSG00000231737(gene)|ensembl:ENSG00000235291(gene)|ensembl:ENSG00000238104(gene)|ensembl:ENST00000376511(transcript)|ensembl:ENST00000383586(transcript)|ensembl:ENST00000420949(transcript)|ensembl:ENST00000424446(transcript)|ensembl:ENST00000426299(transcript)|ensembl:ENST00000429597(transcript)|ensembl:ENST00000449113(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0016604"(nuclear body)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0046872"(metal ion binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:1904290"(negative regulation of mitotic DNA damage checkpoint)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR017923|interpro:IPR035441|interpro:IPR036855|mint:Q96QC0|go:"GO:0000785"(chromatin) - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nnIXgp4JwA+gwrJU9DjLUW2HhtU9606 rogid:ZWueXxqNFYPT0WhbfYdR3d2H2G89606 rigid:7+vUIxPdpnBks7GeiP1ApkaO86M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94992 uniprotkb:P62140 intact:EBI-2832510|uniprotkb:B2R8Y5|ensembl:ENSP00000328773 intact:EBI-352350|uniprotkb:P37140|uniprotkb:Q5U087|uniprotkb:Q6FG45|uniprotkb:D6W565|uniprotkb:B2R5V4|ensembl:ENSP00000296122|ensembl:ENSP00000351298|ensembl:ENSP00000378769 psi-mi:hexi1_human(display_long)|uniprotkb:HEXIM1(gene name)|psi-mi:HEXIM1(display_short)|uniprotkb:CLP1(gene name synonym)|uniprotkb:EDG1(gene name synonym)|uniprotkb:HIS1(gene name synonym)|uniprotkb:MAQ1(gene name synonym)|uniprotkb:Cardiac lineage protein 1(gene name synonym)|uniprotkb:Estrogen down-regulated gene 1 protein(gene name synonym)|uniprotkb:Hexamethylene bis-acetamide-inducible protein 1(gene name synonym)|uniprotkb:Menage a quatre protein 1(gene name synonym) psi-mi:pp1b_human(display_long)|uniprotkb:PPP1CB(gene name)|psi-mi:PPP1CB(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479174|imex:IM-26985-547 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186834(gene)|ensembl:ENST00000332499(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0017069"(snRNA binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|interpro:IPR024872|mint:O94992|rcsb pdb:3S9G|rcsb pdb:2GD7|refseq:NP_006451.1|dip:DIP-46463N refseq:NP_002700.1|refseq:NP_996759.1|ensembl:ENSG00000213639(gene)|ensembl:ENST00000296122(transcript)|ensembl:ENST00000358506(transcript)|ensembl:ENST00000395366(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000165"(MAPK cascade)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0016791"(phosphatase activity)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042587"(glycogen granule)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0046872"(metal ion binding)|go:"GO:0050115"(myosin-light-chain-phosphatase activity)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|mint:P62140|reactome:R-HSA-163560|reactome:R-HSA-2173788|reactome:R-HSA-2565942|reactome:R-HSA-400253|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-5673000|reactome:R-HSA-9660537|dip:DIP-33220N - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nnIXgp4JwA+gwrJU9DjLUW2HhtU9606 rogid:VtNJVyimeiEuRDDWtGswTqoSOH89606 rigid:7+vUIxPdpnBks7GeiP1ApkaO86M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94992 uniprotkb:P08865 intact:EBI-2832510|uniprotkb:B2R8Y5|ensembl:ENSP00000328773 intact:EBI-354112|uniprotkb:Q6NSD1|uniprotkb:Q6NXQ8|uniprotkb:Q86VC0|uniprotkb:P11085|uniprotkb:P12030|uniprotkb:Q16471|uniprotkb:Q6IPD1|uniprotkb:Q6IPD2|ensembl:ENSP00000346067 psi-mi:hexi1_human(display_long)|uniprotkb:HEXIM1(gene name)|psi-mi:HEXIM1(display_short)|uniprotkb:CLP1(gene name synonym)|uniprotkb:EDG1(gene name synonym)|uniprotkb:HIS1(gene name synonym)|uniprotkb:MAQ1(gene name synonym)|uniprotkb:Cardiac lineage protein 1(gene name synonym)|uniprotkb:Estrogen down-regulated gene 1 protein(gene name synonym)|uniprotkb:Hexamethylene bis-acetamide-inducible protein 1(gene name synonym)|uniprotkb:Menage a quatre protein 1(gene name synonym) psi-mi:rssa_human(display_long)|uniprotkb:RPSA(gene name)|psi-mi:RPSA(display_short)|uniprotkb:LAMBR(gene name synonym)|uniprotkb:LAMR1(gene name synonym)|uniprotkb:Laminin receptor 1(gene name synonym)|uniprotkb:37/67 kDa laminin receptor(gene name synonym)|uniprotkb:Laminin-binding protein precursor p40(gene name synonym)|uniprotkb:Colon carcinoma laminin-binding protein(gene name synonym)|uniprotkb:NEM/1CHD4(gene name synonym)|uniprotkb:Multidrug resistance-associated protein MGr1-Ag(gene name synonym)|uniprotkb:37 kDa laminin receptor precursor(gene name synonym)|uniprotkb:67 kDa laminin receptor(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479174|imex:IM-26985-547 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186834(gene)|ensembl:ENST00000332499(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0017069"(snRNA binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|interpro:IPR024872|mint:O94992|rcsb pdb:3S9G|rcsb pdb:2GD7|refseq:NP_006451.1|dip:DIP-46463N refseq:NP_002286.2|refseq:NP_001291217.1|dip:DIP-32878N|ensembl:ENSG00000168028(gene)|ensembl:ENST00000301821(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005055"(laminin receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0007155"(cell adhesion)|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6ZOJ|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0043022"(ribosome binding)|go:"GO:0043236"(laminin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001865(Ribosomal protein S2)|interpro:IPR005707(Ribosomal protein S2, eukaryotic/archaeal)|interpro:IPR018130|interpro:IPR023591|interpro:IPR027498|interpro:IPR027504|interpro:IPR032281|mint:P08865|rcsb pdb:3BCH|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5 - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nnIXgp4JwA+gwrJU9DjLUW2HhtU9606 rogid:Jpv3I3G5C297fHfNwIqyB9Pf8/A9606 rigid:7+vUIxPdpnBks7GeiP1ApkaO86M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94992 uniprotkb:Q8WWM7 intact:EBI-2832510|uniprotkb:B2R8Y5|ensembl:ENSP00000328773 intact:EBI-948363|ensembl:ENSP00000338718|uniprotkb:O95135|uniprotkb:Q6NVJ8|uniprotkb:Q6PJW6|uniprotkb:Q8IU61|uniprotkb:Q8IU95|uniprotkb:Q8WWM3|uniprotkb:Q8WWM4|uniprotkb:Q8WWM5|uniprotkb:Q8WWM6|uniprotkb:Q99703|uniprotkb:B9EGM2|uniprotkb:E9PAR9|uniprotkb:A8K1R6|uniprotkb:Q63ZY4 psi-mi:hexi1_human(display_long)|uniprotkb:HEXIM1(gene name)|psi-mi:HEXIM1(display_short)|uniprotkb:CLP1(gene name synonym)|uniprotkb:EDG1(gene name synonym)|uniprotkb:HIS1(gene name synonym)|uniprotkb:MAQ1(gene name synonym)|uniprotkb:Cardiac lineage protein 1(gene name synonym)|uniprotkb:Estrogen down-regulated gene 1 protein(gene name synonym)|uniprotkb:Hexamethylene bis-acetamide-inducible protein 1(gene name synonym)|uniprotkb:Menage a quatre protein 1(gene name synonym) psi-mi:atx2l_human(display_long)|uniprotkb:Ataxin-2 domain protein(gene name synonym)|uniprotkb:Ataxin-2-related protein(gene name synonym)|uniprotkb:ATXN2L(gene name)|psi-mi:ATXN2L(display_short)|uniprotkb:A2D(gene name synonym)|uniprotkb:A2LG(gene name synonym)|uniprotkb:A2LP(gene name synonym)|uniprotkb:A2RP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479174|imex:IM-26985-547 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186834(gene)|ensembl:ENST00000332499(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0017069"(snRNA binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|interpro:IPR024872|mint:O94992|rcsb pdb:3S9G|rcsb pdb:2GD7|refseq:NP_006451.1|dip:DIP-46463N ensembl:ENSG00000168488(gene)|ensembl:ENST00000336783(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045296"(cadherin binding)|interpro:IPR009604(Ataxin-2, N-terminal)|interpro:IPR009818(Ataxin-2, C-terminal)|interpro:IPR025852|mint:Q8WWM7|refseq:NP_009176.2|refseq:NP_663760.1|refseq:NP_680780.1|refseq:NP_680781.1|refseq:XP_005255123.1|refseq:NP_059867.3|refseq:NP_680782.1 - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nnIXgp4JwA+gwrJU9DjLUW2HhtU9606 rogid:t7lrS10IM/5pt+rrbqBRowZ6b+09606 rigid:7+vUIxPdpnBks7GeiP1ApkaO86M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94992 uniprotkb:Q8N684 intact:EBI-2832510|uniprotkb:B2R8Y5|ensembl:ENSP00000328773 intact:EBI-746909|uniprotkb:C9K0Q4|uniprotkb:Q7Z3H9|uniprotkb:Q9H025|uniprotkb:Q9H9V1|uniprotkb:B3KU04|ensembl:ENSP00000378352 psi-mi:hexi1_human(display_long)|uniprotkb:HEXIM1(gene name)|psi-mi:HEXIM1(display_short)|uniprotkb:CLP1(gene name synonym)|uniprotkb:EDG1(gene name synonym)|uniprotkb:HIS1(gene name synonym)|uniprotkb:MAQ1(gene name synonym)|uniprotkb:Cardiac lineage protein 1(gene name synonym)|uniprotkb:Estrogen down-regulated gene 1 protein(gene name synonym)|uniprotkb:Hexamethylene bis-acetamide-inducible protein 1(gene name synonym)|uniprotkb:Menage a quatre protein 1(gene name synonym) psi-mi:cpsf7_human(display_long)|uniprotkb:Cleavage and polyadenylation specificity factor 59 kDa subunit(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 59 kDa subunit(gene name synonym)|uniprotkb:CPSF7(gene name)|psi-mi:CPSF7(display_short)|uniprotkb:Cleavage factor Im complex 59 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479174|imex:IM-26985-547 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186834(gene)|ensembl:ENST00000332499(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0017069"(snRNA binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|interpro:IPR024872|mint:O94992|rcsb pdb:3S9G|rcsb pdb:2GD7|refseq:NP_006451.1|dip:DIP-46463N refseq:NP_001129512.1|refseq:NP_001136037.1|refseq:NP_079087.3|refseq:XP_011543560.1|refseq:XP_011543561.1|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0016020"(membrane)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034770|interpro:IPR034772|interpro:IPR034773|interpro:IPR035979|mint:Q8N684|rcsb pdb:3N9U|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|ensembl:ENSG00000149532(gene)|ensembl:ENST00000394888(transcript)|refseq:XP_005274356.1|reactome:R-HSA-9013422 - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nnIXgp4JwA+gwrJU9DjLUW2HhtU9606 rogid:bfliZhw27GRZMSQpYRZ/x/tWGh49606 rigid:7+vUIxPdpnBks7GeiP1ApkaO86M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94992 uniprotkb:Q9BXS6 intact:EBI-2832510|uniprotkb:B2R8Y5|ensembl:ENSP00000328773 intact:EBI-2555618|uniprotkb:J3KN21|uniprotkb:Q8TBT4|uniprotkb:Q9UI70|uniprotkb:Q96E58|uniprotkb:Q9NZ85|uniprotkb:Q9GZM9|uniprotkb:Q96FJ1|uniprotkb:Q53GW2|ensembl:ENSP00000453403|ensembl:ENSP00000499238|uniprotkb:B4DDF1|uniprotkb:E7ERR5 psi-mi:hexi1_human(display_long)|uniprotkb:HEXIM1(gene name)|psi-mi:HEXIM1(display_short)|uniprotkb:CLP1(gene name synonym)|uniprotkb:EDG1(gene name synonym)|uniprotkb:HIS1(gene name synonym)|uniprotkb:MAQ1(gene name synonym)|uniprotkb:Cardiac lineage protein 1(gene name synonym)|uniprotkb:Estrogen down-regulated gene 1 protein(gene name synonym)|uniprotkb:Hexamethylene bis-acetamide-inducible protein 1(gene name synonym)|uniprotkb:Menage a quatre protein 1(gene name synonym) psi-mi:nusap_human(display_long)|uniprotkb:ANKT(gene name synonym)|uniprotkb:BM-037(orf name)|uniprotkb:PRO0310(orf name)|uniprotkb:NUSAP1(gene name)|psi-mi:NUSAP1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479174|imex:IM-26985-547 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186834(gene)|ensembl:ENST00000332499(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0017069"(snRNA binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|interpro:IPR024872|mint:O94992|rcsb pdb:3S9G|rcsb pdb:2GD7|refseq:NP_006451.1|dip:DIP-46463N refseq:NP_001230071.1|refseq:NP_057443.2|refseq:NP_060924.4|ensembl:ENSG00000137804(gene)|ensembl:ENST00000559596(transcript)|ensembl:ENST00000668273(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008017"(microtubule binding)|go:"GO:0040001"(establishment of mitotic spindle localization)|go:"GO:0045840"(positive regulation of mitotic nuclear division)|go:"GO:0072686"(mitotic spindle)|interpro:IPR026756|mint:Q9BXS6|refseq:NP_001288065.1|refseq:NP_001230072.1|refseq:NP_001230073.1|refseq:XP_005254487.1 - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nnIXgp4JwA+gwrJU9DjLUW2HhtU9606 rogid:cru0jLd0lg3x59MrNS4Zej6/Lw49606 rigid:7+vUIxPdpnBks7GeiP1ApkaO86M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94992 uniprotkb:O43809 intact:EBI-2832510|uniprotkb:B2R8Y5|ensembl:ENSP00000328773 intact:EBI-355720|uniprotkb:Q6IB85|uniprotkb:Q6NE84|ensembl:ENSP00000300291 psi-mi:hexi1_human(display_long)|uniprotkb:HEXIM1(gene name)|psi-mi:HEXIM1(display_short)|uniprotkb:CLP1(gene name synonym)|uniprotkb:EDG1(gene name synonym)|uniprotkb:HIS1(gene name synonym)|uniprotkb:MAQ1(gene name synonym)|uniprotkb:Cardiac lineage protein 1(gene name synonym)|uniprotkb:Estrogen down-regulated gene 1 protein(gene name synonym)|uniprotkb:Hexamethylene bis-acetamide-inducible protein 1(gene name synonym)|uniprotkb:Menage a quatre protein 1(gene name synonym) psi-mi:cpsf5_human(display_long)|uniprotkb:NUDT21(gene name)|psi-mi:NUDT21(display_short)|uniprotkb:CFIM25(gene name synonym)|uniprotkb:CPSF25(gene name synonym)|uniprotkb:CPSF5(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 25 kDa subunit(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 21(gene name synonym)|uniprotkb:Cleavage factor Im complex 25 kDa subunit(gene name synonym)|uniprotkb:Nudix hydrolase 21(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 68 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479174|imex:IM-26985-547 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186834(gene)|ensembl:ENST00000332499(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0017069"(snRNA binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|interpro:IPR024872|mint:O94992|rcsb pdb:3S9G|rcsb pdb:2GD7|refseq:NP_006451.1|dip:DIP-46463N refseq:NP_008937.1|ensembl:ENSG00000167005(gene)|ensembl:ENST00000300291(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006397"(mRNA processing)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0031439"(positive regulation of mRNA cleavage)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042382"(paraspeckles)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|go:"GO:1900365"(positive regulation of mRNA polyadenylation)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:2000738"(positive regulation of stem cell differentiation)|go:"GO:2000975"(positive regulation of pro-B cell differentiation)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR016706(Cleavage and polyadenylation specificity factor, 25 kDa subunit)|mint:O43809|rcsb pdb:2CL3|rcsb pdb:2J8Q|rcsb pdb:3BAP|rcsb pdb:3BHO|rcsb pdb:3MDG|rcsb pdb:3MDI|rcsb pdb:3N9U|rcsb pdb:3P5T|rcsb pdb:3P6Y|rcsb pdb:3Q2S|rcsb pdb:3Q2T|rcsb pdb:5R4P|rcsb pdb:5R4Q|rcsb pdb:5R4R|rcsb pdb:5R4S|rcsb pdb:5R4T|rcsb pdb:5R4U|rcsb pdb:5R64|rcsb pdb:5R65|rcsb pdb:5R66|rcsb pdb:5R67|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|dip:DIP-42502N - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nnIXgp4JwA+gwrJU9DjLUW2HhtU9606 rogid:Acad4mYVuS+Eox+X2CH8PYUkGAA9606 rigid:7+vUIxPdpnBks7GeiP1ApkaO86M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94992 uniprotkb:Q86XP3 intact:EBI-2832510|uniprotkb:B2R8Y5|ensembl:ENSP00000328773 intact:EBI-722353|uniprotkb:A6NML1|uniprotkb:O75619|uniprotkb:Q68G51|uniprotkb:Q96BK1|uniprotkb:Q96HR7|uniprotkb:Q9Y3V8|uniprotkb:A8KA43|intact:EBI-2555393|ensembl:ENSP00000374574|ensembl:ENSP00000463561|ensembl:ENSP00000464050 psi-mi:hexi1_human(display_long)|uniprotkb:HEXIM1(gene name)|psi-mi:HEXIM1(display_short)|uniprotkb:CLP1(gene name synonym)|uniprotkb:EDG1(gene name synonym)|uniprotkb:HIS1(gene name synonym)|uniprotkb:MAQ1(gene name synonym)|uniprotkb:Cardiac lineage protein 1(gene name synonym)|uniprotkb:Estrogen down-regulated gene 1 protein(gene name synonym)|uniprotkb:Hexamethylene bis-acetamide-inducible protein 1(gene name synonym)|uniprotkb:Menage a quatre protein 1(gene name synonym) psi-mi:ddx42_human(display_long)|uniprotkb:DEAD box protein 42(gene name synonym)|uniprotkb:Splicing factor 3B-associated 125 kDa protein(gene name synonym)|uniprotkb:RNA helicase-related protein(gene name synonym)|uniprotkb:RNA helicase-like protein(gene name synonym)|uniprotkb:SF3b DEAD box protein(gene name synonym)|uniprotkb:DDX42(gene name)|psi-mi:DDX42(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479174|imex:IM-26985-547 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186834(gene)|ensembl:ENST00000332499(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0017069"(snRNA binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|interpro:IPR024872|mint:O94992|rcsb pdb:3S9G|rcsb pdb:2GD7|refseq:NP_006451.1|dip:DIP-46463N refseq:NP_031398.2|refseq:NP_987095.1|refseq:XP_006721720.1|refseq:XP_016879600.1|ensembl:ENSG00000198231(gene)|ensembl:ENST00000389924(transcript)|ensembl:ENST00000578681(transcript)|ensembl:ENST00000583590(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008104"(protein localization)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q86XP3|reactome:R-HSA-72163|reactome:R-HSA-72165 - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nnIXgp4JwA+gwrJU9DjLUW2HhtU9606 rogid:3vZn92rr6cO8qSZJdyq1fguSc489606 rigid:7+vUIxPdpnBks7GeiP1ApkaO86M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94992 uniprotkb:P63241 intact:EBI-2832510|uniprotkb:B2R8Y5|ensembl:ENSP00000328773 intact:EBI-373150|uniprotkb:P10159|uniprotkb:Q16182|uniprotkb:Q7L7L3|uniprotkb:Q7Z4L1|uniprotkb:Q9D0G2|uniprotkb:A8K9A0|uniprotkb:D3DTP2|ensembl:ENSP00000336776|ensembl:ENSP00000390677|ensembl:ENSP00000396073|ensembl:ENSP00000458269|ensembl:ENSP00000459196|ensembl:ENSP00000459611|ensembl:ENSP00000499855|ensembl:ENSP00000499995|ensembl:ENSP00000500414|ensembl:ENSP00000500624|ensembl:ENSP00000500717|ensembl:ENSP00000500847 psi-mi:hexi1_human(display_long)|uniprotkb:HEXIM1(gene name)|psi-mi:HEXIM1(display_short)|uniprotkb:CLP1(gene name synonym)|uniprotkb:EDG1(gene name synonym)|uniprotkb:HIS1(gene name synonym)|uniprotkb:MAQ1(gene name synonym)|uniprotkb:Cardiac lineage protein 1(gene name synonym)|uniprotkb:Estrogen down-regulated gene 1 protein(gene name synonym)|uniprotkb:Hexamethylene bis-acetamide-inducible protein 1(gene name synonym)|uniprotkb:Menage a quatre protein 1(gene name synonym) psi-mi:if5a1_human(display_long)|uniprotkb:EIF5A(gene name)|psi-mi:EIF5A(display_short)|uniprotkb:Eukaryotic initiation factor 5A isoform 1(gene name synonym)|uniprotkb:eIF-4D(gene name synonym)|uniprotkb:Rev-binding factor(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479174|imex:IM-26985-547 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186834(gene)|ensembl:ENST00000332499(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0017069"(snRNA binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|interpro:IPR024872|mint:O94992|rcsb pdb:3S9G|rcsb pdb:2GD7|refseq:NP_006451.1|dip:DIP-46463N refseq:NP_001137232.1|refseq:NP_001137233.1|refseq:NP_001137234.1|refseq:NP_001961.1|refseq:XP_005256566.1|ensembl:ENSG00000132507(gene)|ensembl:ENSG00000288145(gene)|ensembl:ENST00000336458(transcript)|ensembl:ENST00000416016(transcript)|ensembl:ENST00000419711(transcript)|ensembl:ENST00000571955(transcript)|ensembl:ENST00000573542(transcript)|ensembl:ENST00000576930(transcript)|ensembl:ENST00000672250(transcript)|ensembl:ENST00000672755(transcript)|ensembl:ENST00000673099(transcript)|ensembl:ENST00000673210(transcript)|ensembl:ENST00000673259(transcript)|ensembl:ENST00000673304(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043022"(ribosome binding)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0045905"(positive regulation of translational termination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0098586"(cellular response to virus)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|interpro:IPR001884("Eukaryotic initiation factor 5A hypusine (eIF-5A)")|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR019769|interpro:IPR020189|mint:P63241|rcsb pdb:1FH4|rcsb pdb:3CPF|rcsb pdb:5DLQ|reactome:R-HSA-204626 - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nnIXgp4JwA+gwrJU9DjLUW2HhtU9606 rogid:/smk81DLs+XvrqXmIZpfvdHHauk9606 rigid:7+vUIxPdpnBks7GeiP1ApkaO86M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94992 uniprotkb:Q7Z417 intact:EBI-2832510|uniprotkb:B2R8Y5|ensembl:ENSP00000328773 intact:EBI-1210753|intact:EBI-10172018|uniprotkb:A1L3A7|uniprotkb:Q9P2M5|uniprotkb:A1L3A6|ensembl:ENSP00000225388 psi-mi:hexi1_human(display_long)|uniprotkb:HEXIM1(gene name)|psi-mi:HEXIM1(display_short)|uniprotkb:CLP1(gene name synonym)|uniprotkb:EDG1(gene name synonym)|uniprotkb:HIS1(gene name synonym)|uniprotkb:MAQ1(gene name synonym)|uniprotkb:Cardiac lineage protein 1(gene name synonym)|uniprotkb:Estrogen down-regulated gene 1 protein(gene name synonym)|uniprotkb:Hexamethylene bis-acetamide-inducible protein 1(gene name synonym)|uniprotkb:Menage a quatre protein 1(gene name synonym) psi-mi:nufp2_human(display_long)|uniprotkb:NUFIP2(gene name)|psi-mi:NUFIP2(display_short)|uniprotkb:KIAA1321(gene name synonym)|uniprotkb:PIG1(orf name)|uniprotkb:FMRP-interacting protein 2(gene name synonym)|uniprotkb:82 kDa FMRP-interacting protein(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 1 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479174|imex:IM-26985-547 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186834(gene)|ensembl:ENST00000332499(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0017069"(snRNA binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|interpro:IPR024872|mint:O94992|rcsb pdb:3S9G|rcsb pdb:2GD7|refseq:NP_006451.1|dip:DIP-46463N refseq:NP_065823.1|dip:DIP-29023N|ensembl:ENSG00000108256(gene)|ensembl:ENST00000225388(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR032747|mint:Q7Z417 - - comment:"author score: 28" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nnIXgp4JwA+gwrJU9DjLUW2HhtU9606 rogid:zdbkRisveP+8g70umfbEPHTnAgk9606 rigid:7+vUIxPdpnBks7GeiP1ApkaO86M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94992 uniprotkb:P35659 intact:EBI-2832510|uniprotkb:B2R8Y5|ensembl:ENSP00000328773 intact:EBI-301977|uniprotkb:Q5TGV4|uniprotkb:Q5TGV5|uniprotkb:B2R6K6|ensembl:ENSP00000498335|ensembl:ENSP00000498653|uniprotkb:B4DN37 psi-mi:hexi1_human(display_long)|uniprotkb:HEXIM1(gene name)|psi-mi:HEXIM1(display_short)|uniprotkb:CLP1(gene name synonym)|uniprotkb:EDG1(gene name synonym)|uniprotkb:HIS1(gene name synonym)|uniprotkb:MAQ1(gene name synonym)|uniprotkb:Cardiac lineage protein 1(gene name synonym)|uniprotkb:Estrogen down-regulated gene 1 protein(gene name synonym)|uniprotkb:Hexamethylene bis-acetamide-inducible protein 1(gene name synonym)|uniprotkb:Menage a quatre protein 1(gene name synonym) psi-mi:dek_human(display_long)|uniprotkb:DEK(gene name)|psi-mi:DEK(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479174|imex:IM-26985-547 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186834(gene)|ensembl:ENST00000332499(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0017069"(snRNA binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|interpro:IPR024872|mint:O94992|rcsb pdb:3S9G|rcsb pdb:2GD7|refseq:NP_006451.1|dip:DIP-46463N ensembl:ENSG00000124795(gene)|ensembl:ENST00000652576(transcript)|ensembl:ENST00000652689(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0019079"(viral genome replication)|go:"GO:0042393"(histone binding)|go:"GO:0043292"(contractile fiber)|go:"GO:2000779"(regulation of double-strand break repair)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR014876(DEK C terminal)|interpro:IPR044198|mint:P35659|rcsb pdb:1Q1V|rcsb pdb:2JX3|reactome:R-HSA-8864260|reactome:R-HSA-5250924|reactome:R-HSA-9616222|refseq:NP_001128181.1|refseq:NP_003463.1 - - comment:"author score: 30" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nnIXgp4JwA+gwrJU9DjLUW2HhtU9606 rogid:vHgpAwD3bj+BnjUPeNSIlouymfg9606 rigid:7+vUIxPdpnBks7GeiP1ApkaO86M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94992 uniprotkb:P11387 intact:EBI-2832510|uniprotkb:B2R8Y5|ensembl:ENSP00000328773 intact:EBI-876302|ensembl:ENSP00000354522|uniprotkb:Q15610|uniprotkb:Q5TFY3|uniprotkb:Q9UJN0|uniprotkb:O43256|uniprotkb:Q12855|uniprotkb:Q12856|uniprotkb:A8KA78|uniprotkb:E1P5W3 psi-mi:hexi1_human(display_long)|uniprotkb:HEXIM1(gene name)|psi-mi:HEXIM1(display_short)|uniprotkb:CLP1(gene name synonym)|uniprotkb:EDG1(gene name synonym)|uniprotkb:HIS1(gene name synonym)|uniprotkb:MAQ1(gene name synonym)|uniprotkb:Cardiac lineage protein 1(gene name synonym)|uniprotkb:Estrogen down-regulated gene 1 protein(gene name synonym)|uniprotkb:Hexamethylene bis-acetamide-inducible protein 1(gene name synonym)|uniprotkb:Menage a quatre protein 1(gene name synonym) psi-mi:top1_human(display_long)|uniprotkb:DNA topoisomerase I(gene name synonym)|uniprotkb:TOP1(gene name)|psi-mi:TOP1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479174|imex:IM-26985-547 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186834(gene)|ensembl:ENST00000332499(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0017069"(snRNA binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|interpro:IPR024872|mint:O94992|rcsb pdb:3S9G|rcsb pdb:2GD7|refseq:NP_006451.1|dip:DIP-46463N ensembl:ENSG00000198900(gene)|ensembl:ENST00000361337(transcript)|go:"GO:0000932"(P-body)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006265"(DNA topological change)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007623"(circadian rhythm)|go:"GO:0012501"(programmed cell death)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032922"(circadian regulation of gene expression)|refseq:NP_003277.1|dip:DIP-36356N|go:"GO:0032993"(protein-DNA complex)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042493"|go:"GO:0043204"(perikaryon)|go:"GO:0097100"(supercoiled DNA binding)|interpro:IPR001631(DNA topoisomerase I, C-terminal)|interpro:IPR008336(DNA topoisomerase I, DNA binding, eukaryotic-type)|interpro:IPR011010(DNA breaking-rejoining enzyme, catalytic core)|interpro:IPR013030(DNA topoisomerase I, DNA binding, mixed alpha/beta motif, eukaryotic-type)|interpro:IPR013034(DNA topoisomerase I, DNA binding, alpha helical motif, eukaryotic-type)|interpro:IPR013499(DNA topoisomerase I, C-terminal, eukaryotic-type)|interpro:IPR013500(DNA topoisomerase I, catalytic core, eukaryotic-type)|interpro:IPR014711(DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type)|interpro:IPR014727(DNA topoisomerase I, catalytic core, alpha/beta subdomain, eukaryotic-type)|interpro:IPR018521|interpro:IPR025834|interpro:IPR036202|mint:P11387|rcsb pdb:1A31|rcsb pdb:1A35|rcsb pdb:1A36|rcsb pdb:1EJ9|rcsb pdb:1K4S|rcsb pdb:1K4T|rcsb pdb:1LPQ|rcsb pdb:1NH3|rcsb pdb:1R49|rcsb pdb:1RR8|rcsb pdb:1RRJ|rcsb pdb:1SC7|rcsb pdb:1SEU|rcsb pdb:1T8I|rcsb pdb:1TL8|reactome:R-HSA-4615885 - - comment:"author score: 32" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nnIXgp4JwA+gwrJU9DjLUW2HhtU9606 rogid:kB+3PVybgNp2mtOmDa7x8sygFuU9606 rigid:7+vUIxPdpnBks7GeiP1ApkaO86M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94992 uniprotkb:Q9H7H0 intact:EBI-2832510|uniprotkb:B2R8Y5|ensembl:ENSP00000328773 intact:EBI-749353|intact:EBI-948255|uniprotkb:Q9BSH1|uniprotkb:Q9BZH2|uniprotkb:Q9BZH3|ensembl:ENSP00000343041 psi-mi:hexi1_human(display_long)|uniprotkb:HEXIM1(gene name)|psi-mi:HEXIM1(display_short)|uniprotkb:CLP1(gene name synonym)|uniprotkb:EDG1(gene name synonym)|uniprotkb:HIS1(gene name synonym)|uniprotkb:MAQ1(gene name synonym)|uniprotkb:Cardiac lineage protein 1(gene name synonym)|uniprotkb:Estrogen down-regulated gene 1 protein(gene name synonym)|uniprotkb:Hexamethylene bis-acetamide-inducible protein 1(gene name synonym)|uniprotkb:Menage a quatre protein 1(gene name synonym) psi-mi:met17_human(display_long)|uniprotkb:METT11D1(gene name synonym)|uniprotkb:Protein RSM22 homolog, mitochondrial(gene name synonym)|uniprotkb:METTL17(gene name)|psi-mi:METTL17(display_short)|uniprotkb:Methyltransferase 11 domain-containing protein 1(gene name synonym)|uniprotkb:False p73 target gene protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479174|imex:IM-26985-547 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186834(gene)|ensembl:ENST00000332499(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0017069"(snRNA binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|interpro:IPR024872|mint:O94992|rcsb pdb:3S9G|rcsb pdb:2GD7|refseq:NP_006451.1|dip:DIP-46463N refseq:NP_001025162.1|refseq:NP_073571.1|ensembl:ENSG00000165792(gene)|ensembl:ENST00000339374(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006412"(translation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0032259"(methylation)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR015324(Ribosomal protein Rsm22, bacterial-type)|interpro:IPR029063|mint:Q9H7H0 - - comment:"author score: 32" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nnIXgp4JwA+gwrJU9DjLUW2HhtU9606 rogid:RAj8jOqwthd7a0Xzi5FWhVKc8OI9606 rigid:7+vUIxPdpnBks7GeiP1ApkaO86M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94992 uniprotkb:P23246 intact:EBI-2832510|uniprotkb:B2R8Y5|ensembl:ENSP00000328773 intact:EBI-355453|uniprotkb:P30808|uniprotkb:Q5SZ71|ensembl:ENSP00000349748 psi-mi:hexi1_human(display_long)|uniprotkb:HEXIM1(gene name)|psi-mi:HEXIM1(display_short)|uniprotkb:CLP1(gene name synonym)|uniprotkb:EDG1(gene name synonym)|uniprotkb:HIS1(gene name synonym)|uniprotkb:MAQ1(gene name synonym)|uniprotkb:Cardiac lineage protein 1(gene name synonym)|uniprotkb:Estrogen down-regulated gene 1 protein(gene name synonym)|uniprotkb:Hexamethylene bis-acetamide-inducible protein 1(gene name synonym)|uniprotkb:Menage a quatre protein 1(gene name synonym) psi-mi:sfpq_human(display_long)|uniprotkb:SFPQ(gene name)|psi-mi:SFPQ(display_short)|uniprotkb:PSF(gene name synonym)|uniprotkb:Polypyrimidine tract-binding protein-associated-splicing factor(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 100 kDa subunit(gene name synonym)|uniprotkb:100 kDa DNA-pairing protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479174|imex:IM-26985-547 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186834(gene)|ensembl:ENST00000332499(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0017069"(snRNA binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|interpro:IPR024872|mint:O94992|rcsb pdb:3S9G|rcsb pdb:2GD7|refseq:NP_006451.1|dip:DIP-46463N refseq:NP_005057.1|ensembl:ENSG00000116560(gene)|ensembl:ENST00000357214(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0003723"(RNA binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0042382"(paraspeckles)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0005634"(nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0048511"(rhythmic process)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:1902177"(positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034525|interpro:IPR034526|interpro:IPR035979|mint:P23246|rcsb pdb:4WII|rcsb pdb:4WIJ|rcsb pdb:4WIK|rcsb pdb:5WPA|rcsb pdb:6NCQ|rcsb pdb:6OWJ|rcsb pdb:6WMZ|rcsb pdb:7LRQ|rcsb pdb:7LRU|reactome:R-HSA-8849468|reactome:R-HSA-9635465|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|refseq:XP_005271169.1|refseq:XP_005271170.1|refseq:XP_005271172.1|refseq:XP_016857542.1|refseq:XP_016857543.1|dip:DIP-31272N - - comment:"author score: 35" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nnIXgp4JwA+gwrJU9DjLUW2HhtU9606 rogid:B7mSc6tthLbSHo0qz0SMZBSl3HA9606 rigid:7+vUIxPdpnBks7GeiP1ApkaO86M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94992 uniprotkb:P62750 intact:EBI-2832510|uniprotkb:B2R8Y5|ensembl:ENSP00000328773 intact:EBI-353254|uniprotkb:P29316|uniprotkb:Q92774|uniprotkb:P39024|uniprotkb:B2R5B2|ensembl:ENSP00000389103 psi-mi:hexi1_human(display_long)|uniprotkb:HEXIM1(gene name)|psi-mi:HEXIM1(display_short)|uniprotkb:CLP1(gene name synonym)|uniprotkb:EDG1(gene name synonym)|uniprotkb:HIS1(gene name synonym)|uniprotkb:MAQ1(gene name synonym)|uniprotkb:Cardiac lineage protein 1(gene name synonym)|uniprotkb:Estrogen down-regulated gene 1 protein(gene name synonym)|uniprotkb:Hexamethylene bis-acetamide-inducible protein 1(gene name synonym)|uniprotkb:Menage a quatre protein 1(gene name synonym) psi-mi:rl23a_human(display_long)|uniprotkb:RPL23A(gene name)|psi-mi:RPL23A(display_short)|uniprotkb:Large ribosomal subunit protein uL23(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479174|imex:IM-26985-547 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186834(gene)|ensembl:ENST00000332499(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0017069"(snRNA binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|interpro:IPR024872|mint:O94992|rcsb pdb:3S9G|rcsb pdb:2GD7|refseq:NP_006451.1|dip:DIP-46463N reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|refseq:NP_000975.2|ensembl:ENSG00000198242(gene)|ensembl:ENST00000422514(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904841"(TORC2 complex binding)|interpro:IPR001014(Ribosomal protein L23, conserved site)|interpro:IPR005633(Ribosomal protein L23/L25, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR013025(Ribosomal protein L25/L23)|interpro:IPR019985|mint:P62750|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS - - comment:"author score: 39" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nnIXgp4JwA+gwrJU9DjLUW2HhtU9606 rogid:lA1ubRFO9/Tl54Z1dKUzoCKvpAo9606 rigid:7+vUIxPdpnBks7GeiP1ApkaO86M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94992 uniprotkb:Q15233 intact:EBI-2832510|uniprotkb:B2R8Y5|ensembl:ENSP00000328773 intact:EBI-350527|ensembl:ENSP00000503233|uniprotkb:O00201|uniprotkb:P30807|uniprotkb:Q12786|uniprotkb:Q9BQC5|ensembl:ENSP00000276079|ensembl:ENSP00000362947|ensembl:ENSP00000406673|ensembl:ENSP00000410299|ensembl:ENSP00000415777|ensembl:ENSP00000503031|ensembl:ENSP00000504314|ensembl:ENSP00000504351|uniprotkb:D3DVV4|uniprotkb:B7Z4C2|uniprotkb:F5GYZ3 psi-mi:hexi1_human(display_long)|uniprotkb:HEXIM1(gene name)|psi-mi:HEXIM1(display_short)|uniprotkb:CLP1(gene name synonym)|uniprotkb:EDG1(gene name synonym)|uniprotkb:HIS1(gene name synonym)|uniprotkb:MAQ1(gene name synonym)|uniprotkb:Cardiac lineage protein 1(gene name synonym)|uniprotkb:Estrogen down-regulated gene 1 protein(gene name synonym)|uniprotkb:Hexamethylene bis-acetamide-inducible protein 1(gene name synonym)|uniprotkb:Menage a quatre protein 1(gene name synonym) psi-mi:nono_human(display_long)|uniprotkb:NONO(gene name)|psi-mi:NONO(display_short)|uniprotkb:NRB54(gene name synonym)|uniprotkb:54 kDa nuclear RNA- and DNA-binding protein(gene name synonym)|uniprotkb:"p54(nrb)"(gene name synonym)|uniprotkb:55 kDa nuclear protein(gene name synonym)|uniprotkb:NMT55(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 52 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479174|imex:IM-26985-547 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000186834(gene)|ensembl:ENST00000332499(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0004861"(cyclin-dependent protein serine/threonine kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0017069"(snRNA binding)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|interpro:IPR024872|mint:O94992|rcsb pdb:3S9G|rcsb pdb:2GD7|refseq:NP_006451.1|dip:DIP-46463N refseq:NP_001138880.1|refseq:NP_001138881.1|refseq:NP_001138882.1|refseq:NP_031389.3|ensembl:ENSG00000147140(gene)|ensembl:ENST00000276079(transcript)|ensembl:ENST00000373841(transcript)|ensembl:ENST00000420903(transcript)|ensembl:ENST00000450092(transcript)|ensembl:ENST00000454976(transcript)|ensembl:ENST00000677274(transcript)|ensembl:ENST00000677446(transcript)|ensembl:ENST00000677612(transcript)|ensembl:ENST00000678231(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0042382"(paraspeckles)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034552|interpro:IPR035979|mint:Q15233|rcsb pdb:3SDE|rcsb pdb:5IFM|rcsb pdb:6WMZ|rcsb pdb:7LRQ|dip:DIP-29951N - - comment:"author score: 40" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nnIXgp4JwA+gwrJU9DjLUW2HhtU9606 rogid:5W3ooO4h0qh3GKO+WjDrLBhihHA9606 rigid:7+vUIxPdpnBks7GeiP1ApkaO86M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H9V9 uniprotkb:Q8WUK0 intact:EBI-2866290|uniprotkb:Q5TBZ6|uniprotkb:Q9H970|uniprotkb:Q5TBZ1|ensembl:ENSP00000387830 intact:EBI-7199479|uniprotkb:Q7Z557|uniprotkb:Q9BXV8|uniprotkb:E9PAT8|intact:MINT-8162697|intact:MINT-8247525|uniprotkb:Q96CR2|ensembl:ENSP00000325958|ensembl:ENSP00000496417 psi-mi:jmjd4_human(display_long)|uniprotkb:JMJD4(gene name)|psi-mi:JMJD4(display_short)|uniprotkb:Jumonji domain-containing protein 4(gene name synonym)|uniprotkb:JmjC domain-containing protein 4(gene name synonym)|uniprotkb:Lysyl-hydroxylase JMJD4(gene name synonym) psi-mi:ptpm1_human(display_long)|uniprotkb:PTPMT1(gene name)|psi-mi:PTPMT1(display_short)|uniprotkb:MOSP(gene name synonym)|uniprotkb:PLIP(gene name synonym)|uniprotkb:PTEN-like phosphatase(gene name synonym)|uniprotkb:Phosphoinositide lipid phosphatase(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase mitochondrial 1(gene name synonym)|uniprotkb:PNAS-129(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479633|imex:IM-26985-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001154937.1|refseq:NP_075383.2|ensembl:ENSG00000081692(gene)|ensembl:ENST00000438896(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0045905"(positive regulation of translational termination)|go:"GO:0046872"(metal ion binding)|go:"GO:0106156"(peptidyl-lysine 4-dioxygenase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q9H9V9 refseq:NP_001137456.1|refseq:NP_783859.1|ensembl:ENSG00000110536(gene)|ensembl:ENSG00000285206(gene)|ensembl:ENST00000326674(transcript)|ensembl:ENST00000647378(transcript)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0008962"(phosphatidylglycerophosphatase activity)|go:"GO:0032049"(cardiolipin biosynthetic process)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:2001242"(regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR029021|interpro:IPR042165|interpro:IPR044596|mint:Q8WUK0|reactome:R-HSA-1483148 - - comment:mint|comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8HSDmpvyEEqseoRK19/RGCbe1mQ9606 rogid:h7MaeKx6Cx3G2KpRm201THlTJqs9606 rigid:NG9HcUJp8Owna3fpMc7gRRc95GY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H9V9 uniprotkb:Q71U36 intact:EBI-2866290|uniprotkb:Q5TBZ6|uniprotkb:Q9H970|uniprotkb:Q5TBZ1|ensembl:ENSP00000387830 intact:EBI-302552|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:A8K0B8|uniprotkb:G3V1U9|intact:EBI-10989786|ensembl:ENSP00000301071|ensembl:ENSP00000439020 psi-mi:jmjd4_human(display_long)|uniprotkb:JMJD4(gene name)|psi-mi:JMJD4(display_short)|uniprotkb:Jumonji domain-containing protein 4(gene name synonym)|uniprotkb:JmjC domain-containing protein 4(gene name synonym)|uniprotkb:Lysyl-hydroxylase JMJD4(gene name synonym) psi-mi:tba1a_human(display_long)|uniprotkb:TUBA1A(gene name)|psi-mi:TUBA1A(display_short)|uniprotkb:Tubulin B-alpha-1(gene name synonym)|uniprotkb:Tubulin alpha-3 chain(gene name synonym)|uniprotkb:Alpha-tubulin 3(gene name synonym)|uniprotkb:TUBA3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479633|imex:IM-26985-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001154937.1|refseq:NP_075383.2|ensembl:ENSG00000081692(gene)|ensembl:ENST00000438896(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0045905"(positive regulation of translational termination)|go:"GO:0046872"(metal ion binding)|go:"GO:0106156"(peptidyl-lysine 4-dioxygenase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q9H9V9 refseq:NP_006000.2|refseq:NP_001257328.1|refseq:NP_001257329.1|dip:DIP-32773N|ensembl:ENSG00000167552(gene)|ensembl:ENST00000295766(transcript)|ensembl:ENST00000301071(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0045121"(membrane raft)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q71U36|rcsb pdb:5JCO|rcsb pdb:6J8F|rcsb pdb:6WSL|rcsb pdb:7C1M|reactome:R-HSA-1445148|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-8955332|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8HSDmpvyEEqseoRK19/RGCbe1mQ9606 rogid:1CzEzrf5y8hrQRPKgWQS1Wm1aCY9606 rigid:NG9HcUJp8Owna3fpMc7gRRc95GY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H9V9 uniprotkb:P13473 intact:EBI-2866290|uniprotkb:Q5TBZ6|uniprotkb:Q9H970|uniprotkb:Q5TBZ1|ensembl:ENSP00000387830 intact:EBI-2907154|uniprotkb:A8K4X5|uniprotkb:Q16641|uniprotkb:Q96J30|uniprotkb:Q99534|uniprotkb:Q9UD93|uniprotkb:D3DTF0|intact:EBI-4324646|uniprotkb:Q6Q3G8|ensembl:ENSP00000200639 psi-mi:jmjd4_human(display_long)|uniprotkb:JMJD4(gene name)|psi-mi:JMJD4(display_short)|uniprotkb:Jumonji domain-containing protein 4(gene name synonym)|uniprotkb:JmjC domain-containing protein 4(gene name synonym)|uniprotkb:Lysyl-hydroxylase JMJD4(gene name synonym) psi-mi:lamp2_human(display_long)|uniprotkb:LAMP2(gene name)|psi-mi:LAMP2(display_short)|uniprotkb:CD107 antigen-like family member B(gene name synonym)|uniprotkb:LGP-96(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479633|imex:IM-26985-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001154937.1|refseq:NP_075383.2|ensembl:ENSG00000081692(gene)|ensembl:ENST00000438896(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0045905"(positive regulation of translational termination)|go:"GO:0046872"(metal ion binding)|go:"GO:0106156"(peptidyl-lysine 4-dioxygenase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q9H9V9 refseq:NP_002285.1|refseq:NP_054701.1|refseq:NP_001116078.1|ensembl:ENSG00000005893(gene)|ensembl:ENST00000200639(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0017038"(protein import)|go:"GO:0019899"(enzyme binding)|go:"GO:0031088"(platelet dense granule membrane)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031902"(late endosome membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0044754"(autolysosome)|go:"GO:0045121"(membrane raft)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0061742"(chaperone-mediated autophagy translocation complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072594"(establishment of protein localization to organelle)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0097637"(integral component of autophagosome membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1905146"(lysosomal protein catabolic process)|go:"GO:1990836"(lysosomal matrix)|interpro:IPR002000("Lysosome-associated membrane glycoprotein (Lamp)/CD68")|interpro:IPR018134|mint:P13473|rcsb pdb:2MOF|rcsb pdb:2MOM|reactome:R-HSA-114608|reactome:R-HSA-6798695|reactome:R-HSA-9613829 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8HSDmpvyEEqseoRK19/RGCbe1mQ9606 rogid:+s4K/qoL3PBwjATJmFDQtqcl/ZQ9606 rigid:NG9HcUJp8Owna3fpMc7gRRc95GY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H9V9 uniprotkb:P83881 intact:EBI-2866290|uniprotkb:Q5TBZ6|uniprotkb:Q9H970|uniprotkb:Q5TBZ1|ensembl:ENSP00000387830 intact:EBI-1054835|uniprotkb:P09896|uniprotkb:P10661|uniprotkb:Q5J9I6|uniprotkb:Q08ES5|ensembl:ENSP00000446503 psi-mi:jmjd4_human(display_long)|uniprotkb:JMJD4(gene name)|psi-mi:JMJD4(display_short)|uniprotkb:Jumonji domain-containing protein 4(gene name synonym)|uniprotkb:JmjC domain-containing protein 4(gene name synonym)|uniprotkb:Lysyl-hydroxylase JMJD4(gene name synonym) psi-mi:rl36a_human(display_long)|uniprotkb:60S ribosomal protein L44(gene name synonym)|uniprotkb:Cell migration-inducing gene 6 protein(gene name synonym)|uniprotkb:RPL36A(gene name)|psi-mi:RPL36A(display_short)|uniprotkb:MIG6(orf name)|uniprotkb:RPL44(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 15 protein(gene name synonym)|uniprotkb:GIG15(orf name)|uniprotkb:Large ribosomal subunit protein eL42(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479633|imex:IM-26985-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001154937.1|refseq:NP_075383.2|ensembl:ENSG00000081692(gene)|ensembl:ENST00000438896(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0045905"(positive regulation of translational termination)|go:"GO:0046872"(metal ion binding)|go:"GO:0106156"(peptidyl-lysine 4-dioxygenase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q9H9V9 refseq:NP_066357.2|ensembl:ENSG00000241343(gene)|ensembl:ENST00000553110(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR000552(Ribosomal protein L44e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|mint:P83881|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8HSDmpvyEEqseoRK19/RGCbe1mQ9606 rogid:OrRyOEVJZbSdttK93KL/DS5YxJ89606 rigid:NG9HcUJp8Owna3fpMc7gRRc95GY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H9V9 uniprotkb:P50402 intact:EBI-2866290|uniprotkb:Q5TBZ6|uniprotkb:Q9H970|uniprotkb:Q5TBZ1|ensembl:ENSP00000387830 intact:EBI-489887|uniprotkb:Q6FI02|ensembl:ENSP00000358857|ensembl:ENSP00000507533 psi-mi:jmjd4_human(display_long)|uniprotkb:JMJD4(gene name)|psi-mi:JMJD4(display_short)|uniprotkb:Jumonji domain-containing protein 4(gene name synonym)|uniprotkb:JmjC domain-containing protein 4(gene name synonym)|uniprotkb:Lysyl-hydroxylase JMJD4(gene name synonym) psi-mi:emd_human(display_long)|uniprotkb:EDMD(gene name synonym)|uniprotkb:STA(gene name synonym)|uniprotkb:EMD(gene name)|psi-mi:EMD(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479633|imex:IM-26985-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001154937.1|refseq:NP_075383.2|ensembl:ENSG00000081692(gene)|ensembl:ENST00000438896(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0045905"(positive regulation of translational termination)|go:"GO:0046872"(metal ion binding)|go:"GO:0106156"(peptidyl-lysine 4-dioxygenase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q9H9V9 refseq:NP_000108.1|ensembl:ENSP00000358857|ensembl:ENSP00000507533|ensembl:ENSG00000102119(gene)|ensembl:ENST00000369842(transcript)|ensembl:ENST00000683627(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071763"(nuclear membrane organization)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR011015(LEM-like fold)|interpro:IPR034989|interpro:IPR035004|mint:P50402|rcsb pdb:1JEI|rcsb pdb:2ODC|rcsb pdb:2ODG|rcsb pdb:6GHD|rcsb pdb:6RPR|rcsb pdb:7NDY|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609523|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|dip:DIP-34638N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8HSDmpvyEEqseoRK19/RGCbe1mQ9606 rogid:hqH2sFjAGwjIGtGX/rjVVFgaYsE9606 rigid:NG9HcUJp8Owna3fpMc7gRRc95GY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H9V9 uniprotkb:P16615 intact:EBI-2866290|uniprotkb:Q5TBZ6|uniprotkb:Q9H970|uniprotkb:Q5TBZ1|ensembl:ENSP00000387830 intact:EBI-358933|uniprotkb:P16614|uniprotkb:A6NDN7|uniprotkb:B4DF05|uniprotkb:Q86VJ2|ensembl:ENSP00000440045 psi-mi:jmjd4_human(display_long)|uniprotkb:JMJD4(gene name)|psi-mi:JMJD4(display_short)|uniprotkb:Jumonji domain-containing protein 4(gene name synonym)|uniprotkb:JmjC domain-containing protein 4(gene name synonym)|uniprotkb:Lysyl-hydroxylase JMJD4(gene name synonym) psi-mi:at2a2_human(display_long)|uniprotkb:ATP2A2(gene name)|psi-mi:ATP2A2(display_short)|uniprotkb:ATP2B(gene name synonym)|uniprotkb:Calcium pump 2(gene name synonym)|uniprotkb:Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform(gene name synonym)|uniprotkb:"Endoplasmic reticulum class 1/2 Ca(2+) ATPase"(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479633|imex:IM-26985-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001154937.1|refseq:NP_075383.2|ensembl:ENSG00000081692(gene)|ensembl:ENST00000438896(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0045905"(positive regulation of translational termination)|go:"GO:0046872"(metal ion binding)|go:"GO:0106156"(peptidyl-lysine 4-dioxygenase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q9H9V9 refseq:NP_001672.1|refseq:NP_733765.1|refseq:XP_011536704.1|ensembl:ENSG00000174437(gene)|ensembl:ENST00000539276(transcript)|go:"GO:0002026"(regulation of the force of heart contraction)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006984"(ER-nucleus signaling pathway)|go:"GO:0007155"(cell adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008544"(epidermis development)|go:"GO:0008553"(P-type proton-exporting transporter activity)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014801"(longitudinal sarcoplasmic reticulum)|go:"GO:0014883"(transition between fast and slow fiber)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016020"(membrane)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019899"(enzyme binding)|go:"GO:0031095"(platelet dense tubular network membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031775"(lutropin-choriogonadotropic hormone receptor binding)|go:"GO:0032469"(endoplasmic reticulum calcium ion homeostasis)|go:"GO:0032470"(positive regulation of endoplasmic reticulum calcium ion concentration)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0033292"(T-tubule organization)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045822"(negative regulation of heart contraction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055119"(relaxation of cardiac muscle)|go:"GO:0061831"(apical ectoplasmic specialization)|go:"GO:0070296"(sarcoplasmic reticulum calcium ion transport)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0086039"(P-type calcium transporter activity involved in regulation of cardiac muscle cell membrane potential)|go:"GO:0090534"(calcium ion-transporting ATPase complex)|go:"GO:0097470"(ribbon synapse)|go:"GO:0098909"(regulation of cardiac muscle cell action potential involved in regulation of contraction)|go:"GO:0120025"(plasma membrane bounded cell projection)|go:"GO:0140056"(organelle localization by membrane tethering)|go:"GO:1900121"(negative regulation of receptor binding)|go:"GO:1903233"(regulation of calcium ion-dependent exocytosis of neurotransmitter)|go:"GO:1903515"(calcium ion transport from cytosol to endoplasmic reticulum)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1990036"(calcium ion import into sarcoplasmic reticulum)|go:"GO:1990456"(mitochondrion-endoplasmic reticulum membrane tethering)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR005782(Calcium ATPase)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|mint:P16615|rcsb pdb:5ZTF|rcsb pdb:6JJU|rcsb pdb:6LLE|rcsb pdb:6LLY|rcsb pdb:6LN5|rcsb pdb:6LN6|rcsb pdb:6LN7|rcsb pdb:6LN8|rcsb pdb:6LN9|rcsb pdb:7BT2|reactome:R-HSA-1912420|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|go:"GO:0000045"(autophagosome assembly)|refseq:XP_005253945.1|dip:DIP-33868N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8HSDmpvyEEqseoRK19/RGCbe1mQ9606 rogid:QlJZW2fprLYahKUrHDOVs28kA2w9606 rigid:NG9HcUJp8Owna3fpMc7gRRc95GY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H9V9 uniprotkb:Q53GQ0 intact:EBI-2866290|uniprotkb:Q5TBZ6|uniprotkb:Q9H970|uniprotkb:Q5TBZ1|ensembl:ENSP00000387830 intact:EBI-2963255|uniprotkb:Q96EA9|ensembl:ENSP00000278353|uniprotkb:A8K9B0|uniprotkb:Q9Y6G8|uniprotkb:Q96JU2|uniprotkb:D3DR23 psi-mi:jmjd4_human(display_long)|uniprotkb:JMJD4(gene name)|psi-mi:JMJD4(display_short)|uniprotkb:Jumonji domain-containing protein 4(gene name synonym)|uniprotkb:JmjC domain-containing protein 4(gene name synonym)|uniprotkb:Lysyl-hydroxylase JMJD4(gene name synonym) psi-mi:dhb12_human(display_long)|uniprotkb:HSD17B12(gene name)|psi-mi:HSD17B12(display_short)|uniprotkb:17-beta-hydroxysteroid dehydrogenase 12(gene name synonym)|uniprotkb:3-ketoacyl-CoA reductase(gene name synonym)|uniprotkb:SDR12C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 12C member 1(gene name synonym)|uniprotkb:Estradiol 17-beta-dehydrogenase 12(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479633|imex:IM-26985-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001154937.1|refseq:NP_075383.2|ensembl:ENSG00000081692(gene)|ensembl:ENST00000438896(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0045905"(positive regulation of translational termination)|go:"GO:0046872"(metal ion binding)|go:"GO:0106156"(peptidyl-lysine 4-dioxygenase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q9H9V9 ensembl:ENSG00000149084(gene)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006703"(estrogen biosynthetic process)|go:"GO:0008201"(heparin binding)|go:"GO:0009923"(fatty acid elongase complex)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016509"(long-chain-3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035338"(long-chain fatty-acyl-CoA biosynthetic process)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0050062"(long-chain-fatty-acyl-CoA reductase activity)|go:"GO:0072582"("17-beta-hydroxysteroid dehydrogenase (NADP+) activity")|ensembl:ENST00000278353(transcript)|go:"GO:0102339"(3-oxo-arachidoyl-CoA reductase activity)|go:"GO:0102341"(3-oxo-lignoceroyl-CoA reductase activity)|go:"GO:0102342"(3-oxo-cerotoyl-CoA reductase activity)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR020904|interpro:IPR036291|mint:Q53GQ0|reactome:R-HSA-193048|reactome:R-HSA-75876|go:"GO:0102340"(3-oxo-behenoyl-CoA reductase activity)|refseq:NP_057226.1 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8HSDmpvyEEqseoRK19/RGCbe1mQ9606 rogid:2R2pFY0c9yRuCvLU2J8n2urR+0o9606 rigid:NG9HcUJp8Owna3fpMc7gRRc95GY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H9V9 uniprotkb:P82914 intact:EBI-2866290|uniprotkb:Q5TBZ6|uniprotkb:Q9H970|uniprotkb:Q5TBZ1|ensembl:ENSP00000387830 intact:EBI-2880040|ensembl:ENSP00000362208|uniprotkb:Q9H2K1|uniprotkb:B2RD82 psi-mi:jmjd4_human(display_long)|uniprotkb:JMJD4(gene name)|psi-mi:JMJD4(display_short)|uniprotkb:Jumonji domain-containing protein 4(gene name synonym)|uniprotkb:JmjC domain-containing protein 4(gene name synonym)|uniprotkb:Lysyl-hydroxylase JMJD4(gene name synonym) psi-mi:rt15_human(display_long)|uniprotkb:MRPS15(gene name)|psi-mi:MRPS15(display_short)|uniprotkb:RPMS15(gene name synonym)|uniprotkb:DC37(orf name)|uniprotkb:Mitochondrial small ribosomal subunit protein uS15m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479633|imex:IM-26985-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001154937.1|refseq:NP_075383.2|ensembl:ENSG00000081692(gene)|ensembl:ENST00000438896(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0045905"(positive regulation of translational termination)|go:"GO:0046872"(metal ion binding)|go:"GO:0106156"(peptidyl-lysine 4-dioxygenase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q9H9V9 rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:6ZSA|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000116898(gene)|ensembl:ENST00000373116(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR000589(Ribosomal protein S15)|interpro:IPR005290(Ribosomal protein S15, bacterial-type)|interpro:IPR009068(S15/NS1, RNA-binding)|mint:P82914|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|refseq:NP_112570.2 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8HSDmpvyEEqseoRK19/RGCbe1mQ9606 rogid:By026WhG4m+ZHrGZyVjtJDs+p3g9606 rigid:NG9HcUJp8Owna3fpMc7gRRc95GY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H9V9 uniprotkb:O15269 intact:EBI-2866290|uniprotkb:Q5TBZ6|uniprotkb:Q9H970|uniprotkb:Q5TBZ1|ensembl:ENSP00000387830 intact:EBI-1044323|uniprotkb:Q5VWB4|uniprotkb:A8K681|uniprotkb:Q96IX6|ensembl:ENSP00000262554 psi-mi:jmjd4_human(display_long)|uniprotkb:JMJD4(gene name)|psi-mi:JMJD4(display_short)|uniprotkb:Jumonji domain-containing protein 4(gene name synonym)|uniprotkb:JmjC domain-containing protein 4(gene name synonym)|uniprotkb:Lysyl-hydroxylase JMJD4(gene name synonym) psi-mi:sptc1_human(display_long)|uniprotkb:Serine-palmitoyl-CoA transferase 1(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 1(gene name synonym)|uniprotkb:SPTLC1(gene name)|psi-mi:SPTLC1(display_short)|uniprotkb:LCB1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479633|imex:IM-26985-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001154937.1|refseq:NP_075383.2|ensembl:ENSG00000081692(gene)|ensembl:ENST00000438896(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0045905"(positive regulation of translational termination)|go:"GO:0046872"(metal ion binding)|go:"GO:0106156"(peptidyl-lysine 4-dioxygenase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q9H9V9 refseq:NP_006406.1|refseq:NP_847894.1|refseq:NP_001268232.1|ensembl:ENSG00000090054(gene)|ensembl:ENST00000262554(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035339"(SPOTS complex)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1904649"(regulation of fat cell apoptotic process)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:O15269|rcsb pdb:6M4N|rcsb pdb:6M4O|rcsb pdb:7CQI|rcsb pdb:7CQK|rcsb pdb:7K0I|rcsb pdb:7K0J|rcsb pdb:7K0K|rcsb pdb:7K0L|rcsb pdb:7K0M|rcsb pdb:7K0N|rcsb pdb:7K0O|rcsb pdb:7K0P|rcsb pdb:7K0Q|reactome:R-HSA-1660661|dip:DIP-45626N - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8HSDmpvyEEqseoRK19/RGCbe1mQ9606 rogid:M/O7lbdRcUwB+r1wpHj2EtSD+kI9606 rigid:NG9HcUJp8Owna3fpMc7gRRc95GY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H9V9 uniprotkb:Q15758 intact:EBI-2866290|uniprotkb:Q5TBZ6|uniprotkb:Q9H970|uniprotkb:Q5TBZ1|ensembl:ENSP00000387830 intact:EBI-356576|uniprotkb:D0EYG6|uniprotkb:B4DR77|uniprotkb:B7ZB81|uniprotkb:E9PC01|uniprotkb:O95720|uniprotkb:Q96RL9|uniprotkb:Q9BWQ3|uniprotkb:Q9UNP2|uniprotkb:A8K9H5|uniprotkb:B4DWS4|ensembl:ENSP00000444408 psi-mi:jmjd4_human(display_long)|uniprotkb:JMJD4(gene name)|psi-mi:JMJD4(display_short)|uniprotkb:Jumonji domain-containing protein 4(gene name synonym)|uniprotkb:JmjC domain-containing protein 4(gene name synonym)|uniprotkb:Lysyl-hydroxylase JMJD4(gene name synonym) psi-mi:aaat_human(display_long)|uniprotkb:ASCT2(gene name synonym)|uniprotkb:M7V1(gene name synonym)|uniprotkb:RDR(gene name synonym)|uniprotkb:RDRC(gene name synonym)|uniprotkb:SLC1A5(gene name)|psi-mi:SLC1A5(display_short)|uniprotkb:Sodium-dependent neutral amino acid transporter type 2(gene name synonym)|uniprotkb:RD114/simian type D retrovirus receptor(gene name synonym)|uniprotkb:Baboon M7 virus receptor(gene name synonym)|uniprotkb:Solute carrier family 1 member 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479633|imex:IM-26985-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001154937.1|refseq:NP_075383.2|ensembl:ENSG00000081692(gene)|ensembl:ENST00000438896(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0045905"(positive regulation of translational termination)|go:"GO:0046872"(metal ion binding)|go:"GO:0106156"(peptidyl-lysine 4-dioxygenase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q9H9V9 refseq:NP_001138617.1|refseq:NP_005619.1|refseq:NP_001138616.1|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0140009"(L-aspartate import across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1903803"(L-glutamine import across plasma membrane)|interpro:IPR001991("Sodium:dicarboxylate symporter")|interpro:IPR018107|interpro:IPR036458|mint:Q15758|rcsb pdb:5LLM|rcsb pdb:5LLU|rcsb pdb:5LM4|rcsb pdb:5MJU|rcsb pdb:6GCT|rcsb pdb:6MP6|rcsb pdb:6MPB|rcsb pdb:6RVX|rcsb pdb:6RVY|reactome:R-HSA-352230|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013409|reactome:R-HSA-9013423|go:"GO:0042470"(melanosome)|ensembl:ENSG00000105281(gene)|ensembl:ENST00000542575(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0006868"(glutamine transport)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010585"(glutamine secretion)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015175"(neutral amino acid transmembrane transporter activity)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015186"(L-glutamine transmembrane transporter activity)|go:"GO:0015194"(L-serine transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015804"(neutral amino acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity) - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8HSDmpvyEEqseoRK19/RGCbe1mQ9606 rogid:nkh427WmAX5SLFm24BvEpyoyAmw9606 rigid:NG9HcUJp8Owna3fpMc7gRRc95GY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H9V9 uniprotkb:Q9Y5M8 intact:EBI-2866290|uniprotkb:Q5TBZ6|uniprotkb:Q9H970|uniprotkb:Q5TBZ1|ensembl:ENSP00000387830 intact:EBI-355393|uniprotkb:Q8N2D8|uniprotkb:Q6P595|ensembl:ENSP00000418401|ensembl:ENSP00000503923 psi-mi:jmjd4_human(display_long)|uniprotkb:JMJD4(gene name)|psi-mi:JMJD4(display_short)|uniprotkb:Jumonji domain-containing protein 4(gene name synonym)|uniprotkb:JmjC domain-containing protein 4(gene name synonym)|uniprotkb:Lysyl-hydroxylase JMJD4(gene name synonym) psi-mi:srprb_human(display_long)|uniprotkb:SRPRB(gene name)|psi-mi:SRPRB(display_short)|uniprotkb:PSEC0230(orf name)|uniprotkb:Protein APMCF1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479633|imex:IM-26985-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001154937.1|refseq:NP_075383.2|ensembl:ENSG00000081692(gene)|ensembl:ENST00000438896(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0045905"(positive regulation of translational termination)|go:"GO:0046872"(metal ion binding)|go:"GO:0106156"(peptidyl-lysine 4-dioxygenase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q9H9V9 refseq:NP_067026.3|ensembl:ENSG00000144867(gene)|ensembl:ENST00000466490(transcript)|ensembl:ENST00000678299(transcript)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005785"(signal recognition particle receptor complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR019009|interpro:IPR027417|mint:Q9Y5M8|rcsb pdb:7NFX|reactome:R-HSA-1799339|reactome:R-HSA-381038|dip:DIP-50218N - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8HSDmpvyEEqseoRK19/RGCbe1mQ9606 rogid:pHUdnCvOhMRYIJg//OJ+SlCard49606 rigid:NG9HcUJp8Owna3fpMc7gRRc95GY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H9V9 uniprotkb:P53985 intact:EBI-2866290|uniprotkb:Q5TBZ6|uniprotkb:Q9H970|uniprotkb:Q5TBZ1|ensembl:ENSP00000387830 intact:EBI-1054708|uniprotkb:Q9NSJ9|uniprotkb:Q5T8R6|uniprotkb:Q49A45|ensembl:ENSP00000416167|ensembl:ENSP00000441065|ensembl:ENSP00000485688|ensembl:ENSP00000358640|ensembl:ENSP00000397106|ensembl:ENSP00000399104|ensembl:ENSP00000486000|ensembl:ENSP00000505879 psi-mi:jmjd4_human(display_long)|uniprotkb:JMJD4(gene name)|psi-mi:JMJD4(display_short)|uniprotkb:Jumonji domain-containing protein 4(gene name synonym)|uniprotkb:JmjC domain-containing protein 4(gene name synonym)|uniprotkb:Lysyl-hydroxylase JMJD4(gene name synonym) psi-mi:mot1_human(display_long)|uniprotkb:Solute carrier family 16 member 1(gene name synonym)|uniprotkb:SLC16A1(gene name)|psi-mi:SLC16A1(display_short)|uniprotkb:MCT1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479633|imex:IM-26985-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001154937.1|refseq:NP_075383.2|ensembl:ENSG00000081692(gene)|ensembl:ENST00000438896(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0045905"(positive regulation of translational termination)|go:"GO:0046872"(metal ion binding)|go:"GO:0106156"(peptidyl-lysine 4-dioxygenase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q9H9V9 refseq:NP_001159968.1|refseq:NP_003042.3|refseq:XP_011540328.1|refseq:XP_011540329.1|ensembl:ENSG00000155380(gene)|ensembl:ENSG00000281917(gene)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0032094"(response to food)|ensembl:ENST00000369626(transcript)|ensembl:ENST00000429288(transcript)|ensembl:ENST00000443580(transcript)|ensembl:ENST00000458229(transcript)|ensembl:ENST00000538576(transcript)|ensembl:ENST00000628110(transcript)|ensembl:ENST00000630362(transcript)|ensembl:ENST00000679803(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008028"(monocarboxylic acid transmembrane transporter activity)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015129"(lactate transmembrane transporter activity)|go:"GO:0015130"(mevalonate transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015718"(monocarboxylic acid transport)|go:"GO:0015728"(mevalonate transport)|go:"GO:0016020"(membrane)|go:"GO:0035879"(plasma membrane lactate transport)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045202"(synapse)|go:"GO:0046943"(carboxylic acid transmembrane transporter activity)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0051780"(behavioral response to nutrient)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0097159"(organic cyclic compound binding)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:0016021"(integral component of membrane)|interpro:IPR004743(Monocarboxylate transporter)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR030757|interpro:IPR036259|mint:P53985|go:"GO:1905039"(carboxylic acid transmembrane transport)|rcsb pdb:6LYY|rcsb pdb:6LZ0|rcsb pdb:7CKO|rcsb pdb:7CKR|rcsb pdb:7DA5|reactome:R-HSA-210991|reactome:R-HSA-433692|reactome:R-HSA-5619070|reactome:R-HSA-70268 - - comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8HSDmpvyEEqseoRK19/RGCbe1mQ9606 rogid:pwaf5lRwviMRyOg4DN2/6J/iMwc9606 rigid:NG9HcUJp8Owna3fpMc7gRRc95GY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H9V9 uniprotkb:P17987 intact:EBI-2866290|uniprotkb:Q5TBZ6|uniprotkb:Q9H970|uniprotkb:Q5TBZ1|ensembl:ENSP00000387830 intact:EBI-356553|uniprotkb:Q15556|uniprotkb:Q5TCM3|uniprotkb:E1P5B2|ensembl:ENSP00000317334 psi-mi:jmjd4_human(display_long)|uniprotkb:JMJD4(gene name)|psi-mi:JMJD4(display_short)|uniprotkb:Jumonji domain-containing protein 4(gene name synonym)|uniprotkb:JmjC domain-containing protein 4(gene name synonym)|uniprotkb:Lysyl-hydroxylase JMJD4(gene name synonym) psi-mi:tcpa_human(display_long)|uniprotkb:CCTA(gene name synonym)|uniprotkb:TCP1(gene name)|psi-mi:TCP1(display_short)|uniprotkb:CCT1(gene name synonym)|uniprotkb:CCT-alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479633|imex:IM-26985-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001154937.1|refseq:NP_075383.2|ensembl:ENSG00000081692(gene)|ensembl:ENST00000438896(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0045905"(positive regulation of translational termination)|go:"GO:0046872"(metal ion binding)|go:"GO:0106156"(peptidyl-lysine 4-dioxygenase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q9H9V9 refseq:NP_110379.2|ensembl:ENSG00000120438(gene)|ensembl:ENST00000321394(transcript)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000792"(heterochromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:2000109"(regulation of macrophage apoptotic process)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044053"(translocation of peptides or proteins into host cell cytoplasm)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|interpro:IPR012715(T-complex protein 1, alpha subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|reactome:R-HSA-8950505|interpro:IPR027413|mint:P17987|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-33676N - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8HSDmpvyEEqseoRK19/RGCbe1mQ9606 rogid:CYJ5rPjKOH3sAP+j0ckdHHu81g49606 rigid:NG9HcUJp8Owna3fpMc7gRRc95GY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H9V9 uniprotkb:Q68CP4 intact:EBI-2866290|uniprotkb:Q5TBZ6|uniprotkb:Q9H970|uniprotkb:Q5TBZ1|ensembl:ENSP00000387830 intact:EBI-2867901|uniprotkb:B4E2V0 psi-mi:jmjd4_human(display_long)|uniprotkb:JMJD4(gene name)|psi-mi:JMJD4(display_short)|uniprotkb:Jumonji domain-containing protein 4(gene name synonym)|uniprotkb:JmjC domain-containing protein 4(gene name synonym)|uniprotkb:Lysyl-hydroxylase JMJD4(gene name synonym) psi-mi:hgnat_human(display_long)|uniprotkb:HGSNAT(gene name)|psi-mi:HGSNAT(display_short)|uniprotkb:TMEM76(gene name synonym)|uniprotkb:Transmembrane protein 76(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479633|imex:IM-26985-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001154937.1|refseq:NP_075383.2|ensembl:ENSG00000081692(gene)|ensembl:ENST00000438896(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0045905"(positive regulation of translational termination)|go:"GO:0046872"(metal ion binding)|go:"GO:0106156"(peptidyl-lysine 4-dioxygenase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q9H9V9 refseq:NP_689632.2|interpro:IPR012429(Protein of unknown function DUF1624)|interpro:IPR040208|mint:Q68CP4|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007041"(lysosomal transport)|go:"GO:0015019"(heparan-alpha-glucosaminide N-acetyltransferase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0035579"(specific granule membrane)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0070821"(tertiary granule membrane)|reactome:R-HSA-2024096|reactome:R-HSA-2206291|reactome:R-HSA-6798695 - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8HSDmpvyEEqseoRK19/RGCbe1mQ9606 rogid:NPw8nihV4yj9Am0bzJzeQdHpntg9606 rigid:NG9HcUJp8Owna3fpMc7gRRc95GY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H9V9 uniprotkb:P61619 intact:EBI-2866290|uniprotkb:Q5TBZ6|uniprotkb:Q9H970|uniprotkb:Q5TBZ1|ensembl:ENSP00000387830 intact:EBI-358919|uniprotkb:Q5JPF8|uniprotkb:P38378|uniprotkb:P57726|uniprotkb:Q8N3U3|uniprotkb:Q8NC71|uniprotkb:Q9BU16|uniprotkb:Q9Y2R3|uniprotkb:Q8N0Z4|ensembl:ENSP00000243253 psi-mi:jmjd4_human(display_long)|uniprotkb:JMJD4(gene name)|psi-mi:JMJD4(display_short)|uniprotkb:Jumonji domain-containing protein 4(gene name synonym)|uniprotkb:JmjC domain-containing protein 4(gene name synonym)|uniprotkb:Lysyl-hydroxylase JMJD4(gene name synonym) psi-mi:s61a1_human(display_long)|uniprotkb:SEC61A1(gene name)|psi-mi:SEC61A1(display_short)|uniprotkb:SEC61A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479633|imex:IM-26985-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001154937.1|refseq:NP_075383.2|ensembl:ENSG00000081692(gene)|ensembl:ENST00000438896(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0045905"(positive regulation of translational termination)|go:"GO:0046872"(metal ion binding)|go:"GO:0106156"(peptidyl-lysine 4-dioxygenase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q9H9V9 refseq:NP_037468.1|ensembl:ENSG00000058262(gene)|ensembl:ENST00000243253(transcript)|go:"GO:0005048"(signal sequence binding)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0039019"(pronephric nephron development)|go:"GO:0043022"(ribosome binding)|go:"GO:0045047"(protein targeting to ER)|interpro:IPR002208(SecY protein)|interpro:IPR019561|interpro:IPR023201|interpro:IPR030659|mint:P61619|rcsb pdb:6W6L|reactome:R-HSA-1236974|reactome:R-HSA-1799339 - - comment:"author score: 27" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8HSDmpvyEEqseoRK19/RGCbe1mQ9606 rogid:C+EzS02H/FYMX2nyfksXpRMs8G09606 rigid:NG9HcUJp8Owna3fpMc7gRRc95GY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H9V9 uniprotkb:Q9H4I3 intact:EBI-2866290|uniprotkb:Q5TBZ6|uniprotkb:Q9H970|uniprotkb:Q5TBZ1|ensembl:ENSP00000387830 intact:EBI-3229670|ensembl:ENSP00000305664|ensembl:ENSP00000370295|ensembl:ENSP00000379171|uniprotkb:Q9H7N1|uniprotkb:Q9UGX6|uniprotkb:Q96ED8|uniprotkb:Q9UGX7|uniprotkb:Q19CC5 psi-mi:jmjd4_human(display_long)|uniprotkb:JMJD4(gene name)|psi-mi:JMJD4(display_short)|uniprotkb:Jumonji domain-containing protein 4(gene name synonym)|uniprotkb:JmjC domain-containing protein 4(gene name synonym)|uniprotkb:Lysyl-hydroxylase JMJD4(gene name synonym) psi-mi:trabd_human(display_long)|uniprotkb:TRABD(gene name)|psi-mi:TRABD(display_short)|uniprotkb:TTG2(gene name synonym)|uniprotkb:Protein TTG2(gene name synonym)|uniprotkb:PP2447(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479633|imex:IM-26985-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001154937.1|refseq:NP_075383.2|ensembl:ENSG00000081692(gene)|ensembl:ENST00000438896(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0045905"(positive regulation of translational termination)|go:"GO:0046872"(metal ion binding)|go:"GO:0106156"(peptidyl-lysine 4-dioxygenase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q9H9V9 ensembl:ENSG00000170638(gene)|ensembl:ENST00000303434(transcript)|ensembl:ENST00000380909(transcript)|ensembl:ENST00000395827(transcript)|interpro:IPR002816(Pheromone shutdown-related, TraB)|mint:Q9H4I3|refseq:NP_079480.2|refseq:NP_001307413.1|refseq:NP_001307414.1|refseq:NP_001307416.1|refseq:NP_001307417.1|refseq:XP_016884433.1 - - comment:"author score: 31" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8HSDmpvyEEqseoRK19/RGCbe1mQ9606 rogid:9jCR5jBtTBh7MqIRiCIq2WECSlA9606 rigid:NG9HcUJp8Owna3fpMc7gRRc95GY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H9V9 uniprotkb:P48643 intact:EBI-2866290|uniprotkb:Q5TBZ6|uniprotkb:Q9H970|uniprotkb:Q5TBZ1|ensembl:ENSP00000387830 intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8 psi-mi:jmjd4_human(display_long)|uniprotkb:JMJD4(gene name)|psi-mi:JMJD4(display_short)|uniprotkb:Jumonji domain-containing protein 4(gene name synonym)|uniprotkb:JmjC domain-containing protein 4(gene name synonym)|uniprotkb:Lysyl-hydroxylase JMJD4(gene name synonym) psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479633|imex:IM-26985-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001154937.1|refseq:NP_075383.2|ensembl:ENSG00000081692(gene)|ensembl:ENST00000438896(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0045905"(positive regulation of translational termination)|go:"GO:0046872"(metal ion binding)|go:"GO:0106156"(peptidyl-lysine 4-dioxygenase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q9H9V9 refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N - - comment:"author score: 34" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8HSDmpvyEEqseoRK19/RGCbe1mQ9606 rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606 rigid:NG9HcUJp8Owna3fpMc7gRRc95GY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H9V9 uniprotkb:P49368 intact:EBI-2866290|uniprotkb:Q5TBZ6|uniprotkb:Q9H970|uniprotkb:Q5TBZ1|ensembl:ENSP00000387830 intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688 psi-mi:jmjd4_human(display_long)|uniprotkb:JMJD4(gene name)|psi-mi:JMJD4(display_short)|uniprotkb:Jumonji domain-containing protein 4(gene name synonym)|uniprotkb:JmjC domain-containing protein 4(gene name synonym)|uniprotkb:Lysyl-hydroxylase JMJD4(gene name synonym) psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479633|imex:IM-26985-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001154937.1|refseq:NP_075383.2|ensembl:ENSG00000081692(gene)|ensembl:ENST00000438896(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0045905"(positive regulation of translational termination)|go:"GO:0046872"(metal ion binding)|go:"GO:0106156"(peptidyl-lysine 4-dioxygenase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q9H9V9 refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N - - comment:"author score: 45" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8HSDmpvyEEqseoRK19/RGCbe1mQ9606 rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606 rigid:NG9HcUJp8Owna3fpMc7gRRc95GY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H9V9 uniprotkb:P50991 intact:EBI-2866290|uniprotkb:Q5TBZ6|uniprotkb:Q9H970|uniprotkb:Q5TBZ1|ensembl:ENSP00000387830 intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958 psi-mi:jmjd4_human(display_long)|uniprotkb:JMJD4(gene name)|psi-mi:JMJD4(display_short)|uniprotkb:Jumonji domain-containing protein 4(gene name synonym)|uniprotkb:JmjC domain-containing protein 4(gene name synonym)|uniprotkb:Lysyl-hydroxylase JMJD4(gene name synonym) psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479633|imex:IM-26985-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001154937.1|refseq:NP_075383.2|ensembl:ENSG00000081692(gene)|ensembl:ENST00000438896(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0045905"(positive regulation of translational termination)|go:"GO:0046872"(metal ion binding)|go:"GO:0106156"(peptidyl-lysine 4-dioxygenase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q9H9V9 refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998 - - comment:"author score: 52" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8HSDmpvyEEqseoRK19/RGCbe1mQ9606 rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606 rigid:NG9HcUJp8Owna3fpMc7gRRc95GY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H9V9 uniprotkb:P50990 intact:EBI-2866290|uniprotkb:Q5TBZ6|uniprotkb:Q9H970|uniprotkb:Q5TBZ1|ensembl:ENSP00000387830 intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788 psi-mi:jmjd4_human(display_long)|uniprotkb:JMJD4(gene name)|psi-mi:JMJD4(display_short)|uniprotkb:Jumonji domain-containing protein 4(gene name synonym)|uniprotkb:JmjC domain-containing protein 4(gene name synonym)|uniprotkb:Lysyl-hydroxylase JMJD4(gene name synonym) psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479633|imex:IM-26985-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001154937.1|refseq:NP_075383.2|ensembl:ENSG00000081692(gene)|ensembl:ENST00000438896(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0045905"(positive regulation of translational termination)|go:"GO:0046872"(metal ion binding)|go:"GO:0106156"(peptidyl-lysine 4-dioxygenase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q9H9V9 refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N - - comment:"author score: 75" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8HSDmpvyEEqseoRK19/RGCbe1mQ9606 rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606 rigid:NG9HcUJp8Owna3fpMc7gRRc95GY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H9V9 uniprotkb:P40227 intact:EBI-2866290|uniprotkb:Q5TBZ6|uniprotkb:Q9H970|uniprotkb:Q5TBZ1|ensembl:ENSP00000387830 intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2 psi-mi:jmjd4_human(display_long)|uniprotkb:JMJD4(gene name)|psi-mi:JMJD4(display_short)|uniprotkb:Jumonji domain-containing protein 4(gene name synonym)|uniprotkb:JmjC domain-containing protein 4(gene name synonym)|uniprotkb:Lysyl-hydroxylase JMJD4(gene name synonym) psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479633|imex:IM-26985-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001154937.1|refseq:NP_075383.2|ensembl:ENSG00000081692(gene)|ensembl:ENST00000438896(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0045905"(positive regulation of translational termination)|go:"GO:0046872"(metal ion binding)|go:"GO:0106156"(peptidyl-lysine 4-dioxygenase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q9H9V9 refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N - - comment:"author score: 102" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8HSDmpvyEEqseoRK19/RGCbe1mQ9606 rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606 rigid:NG9HcUJp8Owna3fpMc7gRRc95GY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H9V9 uniprotkb:Q99832 intact:EBI-2866290|uniprotkb:Q5TBZ6|uniprotkb:Q9H970|uniprotkb:Q5TBZ1|ensembl:ENSP00000387830 intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091 psi-mi:jmjd4_human(display_long)|uniprotkb:JMJD4(gene name)|psi-mi:JMJD4(display_short)|uniprotkb:Jumonji domain-containing protein 4(gene name synonym)|uniprotkb:JmjC domain-containing protein 4(gene name synonym)|uniprotkb:Lysyl-hydroxylase JMJD4(gene name synonym) psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479633|imex:IM-26985-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001154937.1|refseq:NP_075383.2|ensembl:ENSG00000081692(gene)|ensembl:ENST00000438896(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0045905"(positive regulation of translational termination)|go:"GO:0046872"(metal ion binding)|go:"GO:0106156"(peptidyl-lysine 4-dioxygenase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q9H9V9 dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422 - - comment:"author score: 116" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8HSDmpvyEEqseoRK19/RGCbe1mQ9606 rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606 rigid:NG9HcUJp8Owna3fpMc7gRRc95GY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H9V9 uniprotkb:P78371 intact:EBI-2866290|uniprotkb:Q5TBZ6|uniprotkb:Q9H970|uniprotkb:Q5TBZ1|ensembl:ENSP00000387830 intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300 psi-mi:jmjd4_human(display_long)|uniprotkb:JMJD4(gene name)|psi-mi:JMJD4(display_short)|uniprotkb:Jumonji domain-containing protein 4(gene name synonym)|uniprotkb:JmjC domain-containing protein 4(gene name synonym)|uniprotkb:Lysyl-hydroxylase JMJD4(gene name synonym) psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479633|imex:IM-26985-23 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001154937.1|refseq:NP_075383.2|ensembl:ENSG00000081692(gene)|ensembl:ENST00000438896(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0045905"(positive regulation of translational termination)|go:"GO:0046872"(metal ion binding)|go:"GO:0106156"(peptidyl-lysine 4-dioxygenase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q9H9V9 refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695 - - comment:"author score: 130" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8HSDmpvyEEqseoRK19/RGCbe1mQ9606 rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606 rigid:NG9HcUJp8Owna3fpMc7gRRc95GY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNL4 uniprotkb:P06702 intact:EBI-2866661|uniprotkb:Q9H3J0|uniprotkb:Q96E15|uniprotkb:Q4VBQ6|uniprotkb:D3DUR8|uniprotkb:A4KYM4|uniprotkb:Q0EF62|uniprotkb:Q0EF63|uniprotkb:A4KYM6|ensembl:ENSP00000380024 intact:EBI-1055001|uniprotkb:Q6FGA1|uniprotkb:Q9NYM0|uniprotkb:Q9UCJ1|uniprotkb:D3DV36|ensembl:ENSP00000357727 psi-mi:ing4_human(display_long)|uniprotkb:ING4(gene name)|psi-mi:ING4(display_short)|uniprotkb:p29ING4(gene name synonym)|uniprotkb:My036(orf name) psi-mi:s10a9_human(display_long)|uniprotkb:S100 calcium-binding protein A9(gene name synonym)|uniprotkb:Calgranulin-B(gene name synonym)|uniprotkb:Migration inhibitory factor-related protein 14(gene name synonym)|uniprotkb:Leukocyte L1 complex heavy chain(gene name synonym)|uniprotkb:Calprotectin L1H subunit(gene name synonym)|uniprotkb:S100A9(gene name)|psi-mi:S100A9(display_short)|uniprotkb:CAGB(gene name synonym)|uniprotkb:CFAG(gene name synonym)|uniprotkb:MRP14(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479510|imex:IM-26985-97 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001121054.1|refseq:NP_001121055.1|refseq:NP_001121056.1|refseq:NP_001121057.1|refseq:NP_001121058.1|refseq:NP_057246.2|dip:DIP-42222N|ensembl:ENSG00000111653(gene)|ensembl:ENST00000396807(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006473"(protein acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|interpro:IPR028651|mint:Q9UNL4|rcsb pdb:2K1J|rcsb pdb:2M1R|rcsb pdb:2PNX|rcsb pdb:2VNF|rcsb pdb:4AFL|reactome:R-HSA-3214847|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028638 refseq:NP_002956.1|rcsb pdb:1XK4|rcsb pdb:4GGF|rcsb pdb:4XJK|rcsb pdb:5I8N|rcsb pdb:5W1F|rcsb pdb:6DS2|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5668599|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-6799990|ensembl:ENSG00000163220(gene)|ensembl:ENST00000368738(transcript)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035662"(Toll-like receptor 4 binding)|go:"GO:0035821"(modulation of process of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0045113"(regulation of integrin biosynthetic process)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070488"(neutrophil aggregation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|mint:P06702|rcsb pdb:1IRJ|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016209"(antioxidant activity)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0030054"(cell junction)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032119"(sequestering of zinc ion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035425"(autocrine signaling)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|dip:DIP-1166N - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:71DYqPEISrr06/kbSTCdA3J23NU9606 rogid:IGnX4DSnv8xMr5pY4T7X7vYos5A9606 rigid:NHmJE13LRwF1tVv2JQWOJLD+sCc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNL4 uniprotkb:P05155 intact:EBI-2866661|uniprotkb:Q9H3J0|uniprotkb:Q96E15|uniprotkb:Q4VBQ6|uniprotkb:D3DUR8|uniprotkb:A4KYM4|uniprotkb:Q0EF62|uniprotkb:Q0EF63|uniprotkb:A4KYM6|ensembl:ENSP00000380024 intact:EBI-1223454|uniprotkb:Q547W3|uniprotkb:Q59EI5|uniprotkb:Q96FE0|uniprotkb:A6NMU0|uniprotkb:A8KAI9|uniprotkb:B2R6L5|uniprotkb:Q16304|uniprotkb:Q7Z455|uniprotkb:Q9UC49|uniprotkb:Q9UCF9|uniprotkb:B4E1F0|uniprotkb:B4E1H2|ensembl:ENSP00000278407|ensembl:ENSP00000504807 psi-mi:ing4_human(display_long)|uniprotkb:ING4(gene name)|psi-mi:ING4(display_short)|uniprotkb:p29ING4(gene name synonym)|uniprotkb:My036(orf name) psi-mi:ic1_human(display_long)|uniprotkb:SERPING1(gene name)|psi-mi:SERPING1(display_short)|uniprotkb:C1IN(gene name synonym)|uniprotkb:C1NH(gene name synonym)|uniprotkb:C1 esterase inhibitor(gene name synonym)|uniprotkb:C1-inhibiting factor(gene name synonym)|uniprotkb:Serpin G1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479510|imex:IM-26985-97 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001121054.1|refseq:NP_001121055.1|refseq:NP_001121056.1|refseq:NP_001121057.1|refseq:NP_001121058.1|refseq:NP_057246.2|dip:DIP-42222N|ensembl:ENSG00000111653(gene)|ensembl:ENST00000396807(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006473"(protein acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|interpro:IPR028651|mint:Q9UNL4|rcsb pdb:2K1J|rcsb pdb:2M1R|rcsb pdb:2PNX|rcsb pdb:2VNF|rcsb pdb:4AFL|reactome:R-HSA-3214847|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028638 refseq:NP_000053.2|refseq:NP_001027466.1|dip:DIP-45635N|ensembl:ENSG00000149131(gene)|ensembl:ENST00000278407(transcript)|ensembl:ENST00000676670(transcript)|go:"GO:0001869"(negative regulation of complement activation, lectin pathway)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0007568"(aging)|go:"GO:0007596"(blood coagulation)|go:"GO:0008015"(blood circulation)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0042730"(fibrinolysis)|go:"GO:0045087"(innate immune response)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR015553(Protease inhibitor I4, serpin C1)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P05155|rcsb pdb:1M6Q|rcsb pdb:2OAY|rcsb pdb:5DU3|rcsb pdb:5DUQ|rcsb pdb:7AKV|reactome:R-HSA-114608|reactome:R-HSA-140837|reactome:R-HSA-9657689|reactome:R-HSA-977606 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:71DYqPEISrr06/kbSTCdA3J23NU9606 rogid:Y7cqCZ6Ryz51dsi6jM86EXdfeWc9606 rigid:NHmJE13LRwF1tVv2JQWOJLD+sCc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNL4 uniprotkb:P01024 intact:EBI-2866661|uniprotkb:Q9H3J0|uniprotkb:Q96E15|uniprotkb:Q4VBQ6|uniprotkb:D3DUR8|uniprotkb:A4KYM4|uniprotkb:Q0EF62|uniprotkb:Q0EF63|uniprotkb:A4KYM6|ensembl:ENSP00000380024 intact:EBI-905851|uniprotkb:A7E236|ensembl:ENSP00000245907 psi-mi:ing4_human(display_long)|uniprotkb:ING4(gene name)|psi-mi:ING4(display_short)|uniprotkb:p29ING4(gene name synonym)|uniprotkb:My036(orf name) psi-mi:co3_human(display_long)|uniprotkb:C3(gene name)|psi-mi:C3(display_short)|uniprotkb:CPAMD1(gene name synonym)|uniprotkb:C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479510|imex:IM-26985-97 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001121054.1|refseq:NP_001121055.1|refseq:NP_001121056.1|refseq:NP_001121057.1|refseq:NP_001121058.1|refseq:NP_057246.2|dip:DIP-42222N|ensembl:ENSG00000111653(gene)|ensembl:ENST00000396807(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006473"(protein acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|interpro:IPR028651|mint:Q9UNL4|rcsb pdb:2K1J|rcsb pdb:2M1R|rcsb pdb:2PNX|rcsb pdb:2VNF|rcsb pdb:4AFL|reactome:R-HSA-3214847|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028638 refseq:NP_000055.2|dip:DIP-35180N|ensembl:ENSG00000125730(gene)|ensembl:ENST00000245907(transcript)|go:"GO:0001798"(positive regulation of type IIa hypersensitivity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001970"(positive regulation of activation of membrane attack complex)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006956"(complement activation)|go:"GO:0006957"(complement activation, alternative pathway)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0007165"(signal transduction)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0009617"(response to bacterium)|go:"GO:0009986"(cell surface)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010828"(positive regulation of glucose transmembrane transport)|go:"GO:0010866"(regulation of triglyceride biosynthetic process)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0016322"(neuron remodeling)|go:"GO:0031715"(C5L2 anaphylatoxin chemotactic receptor binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035846"(oviduct epithelium development)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0060100"(positive regulation of phagocytosis, engulfment)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0097242"(amyloid-beta clearance)|go:"GO:0097278"(complement-dependent cytotoxicity)|go:"GO:0150062"(complement-mediated synapse pruning)|go:"GO:0150064"(vertebrate eye-specific patterning)|go:"GO:1905114"(cell surface receptor signaling pathway involved in cell-cell signaling)|go:"GO:2000427"(positive regulation of apoptotic cell clearance)|interpro:IPR000020(Anaphylatoxin/fibulin)|interpro:IPR001134(Netrin, C-terminal)|interpro:IPR001599(Alpha-2-macroglobulin)|interpro:IPR001840(Complement C3a/C4a/C5a anaphylatoxin)|interpro:IPR002890(Alpha-2-macroglobulin, N-terminal)|interpro:IPR008930(Terpenoid cylases/protein prenyltransferase alpha-alpha toroid)|interpro:IPR008993(TIMP-like, OB-fold)|interpro:IPR009048(Alpha-macroglobulin, receptor-binding)|interpro:IPR011625(Alpha-2-macroglobulin, N-terminal 2)|interpro:IPR011626(A-macroglobulin complement component)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR018081|interpro:IPR018933|interpro:IPR019742|interpro:IPR035711|interpro:IPR035815|interpro:IPR036595|interpro:IPR040839|interpro:IPR041425|interpro:IPR041555|mint:P01024|rcsb pdb:1C3D|rcsb pdb:1GHQ|rcsb pdb:1W2S|rcsb pdb:2A73|rcsb pdb:2A74|rcsb pdb:2GOX|rcsb pdb:2I07|rcsb pdb:2ICE|rcsb pdb:2ICF|rcsb pdb:2NOJ|rcsb pdb:2QKI|rcsb pdb:2WII|rcsb pdb:2WIN|rcsb pdb:2WY7|rcsb pdb:2WY8|rcsb pdb:2XQW|rcsb pdb:2XWB|rcsb pdb:2XWJ|rcsb pdb:3D5R|rcsb pdb:3D5S|rcsb pdb:3G6J|rcsb pdb:3L3O|rcsb pdb:3L5N|rcsb pdb:3NMS|rcsb pdb:3OED|rcsb pdb:3OHX|rcsb pdb:3OXU|rcsb pdb:3RJ3|rcsb pdb:3T4A|rcsb pdb:4HW5|rcsb pdb:4HWJ|rcsb pdb:4I6O|rcsb pdb:4M76|rcsb pdb:4ONT|rcsb pdb:4ZH1|rcsb pdb:5FO7|rcsb pdb:5FO8|rcsb pdb:5FO9|rcsb pdb:5FOA|rcsb pdb:5FOB|rcsb pdb:5NBQ|rcsb pdb:5O32|rcsb pdb:5O35|rcsb pdb:6EHG|rcsb pdb:6RMT|rcsb pdb:6RMU|rcsb pdb:6RUR|rcsb pdb:6RUV|rcsb pdb:6S0B|rcsb pdb:6YO6|reactome:R-HSA-173736|reactome:R-HSA-174577|reactome:R-HSA-198933|reactome:R-HSA-375276|reactome:R-HSA-381426|reactome:R-HSA-418594|reactome:R-HSA-6798695|reactome:R-HSA-8957275|reactome:R-HSA-9660826|reactome:R-HSA-977606 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:71DYqPEISrr06/kbSTCdA3J23NU9606 rogid:6Axa89cCPpUXFsLnd7sCurZzLYI9606 rigid:NHmJE13LRwF1tVv2JQWOJLD+sCc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNL4 uniprotkb:P01008 intact:EBI-2866661|uniprotkb:Q9H3J0|uniprotkb:Q96E15|uniprotkb:Q4VBQ6|uniprotkb:D3DUR8|uniprotkb:A4KYM4|uniprotkb:Q0EF62|uniprotkb:Q0EF63|uniprotkb:A4KYM6|ensembl:ENSP00000380024 intact:EBI-1039832|uniprotkb:P78439|uniprotkb:P78447|uniprotkb:Q13815|uniprotkb:Q7KZ43|uniprotkb:B2R6P0|uniprotkb:Q5TC78|uniprotkb:Q7KZ97|uniprotkb:Q9UC78|ensembl:ENSP00000356671 psi-mi:ing4_human(display_long)|uniprotkb:ING4(gene name)|psi-mi:ING4(display_short)|uniprotkb:p29ING4(gene name synonym)|uniprotkb:My036(orf name) psi-mi:ant3_human(display_long)|uniprotkb:SERPINC1(gene name)|psi-mi:SERPINC1(display_short)|uniprotkb:AT3(gene name synonym)|uniprotkb:PRO0309(orf name)|uniprotkb:Serpin C1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479510|imex:IM-26985-97 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001121054.1|refseq:NP_001121055.1|refseq:NP_001121056.1|refseq:NP_001121057.1|refseq:NP_001121058.1|refseq:NP_057246.2|dip:DIP-42222N|ensembl:ENSG00000111653(gene)|ensembl:ENST00000396807(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006473"(protein acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|interpro:IPR028651|mint:Q9UNL4|rcsb pdb:2K1J|rcsb pdb:2M1R|rcsb pdb:2PNX|rcsb pdb:2VNF|rcsb pdb:4AFL|reactome:R-HSA-3214847|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028638 refseq:NP_000479.1|ensembl:ENSG00000117601(gene)|ensembl:ENST00000367698(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0002438"(acute inflammatory response to antigenic stimulus)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0007584"(response to nutrient)|go:"GO:0007595"(lactation)|go:"GO:0007596"(blood coagulation)|go:"GO:0008201"(heparin binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:2000266"(regulation of blood coagulation, intrinsic pathway)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR015555(Protease inhibitor I4, serpin, antithrombin-III)|interpro:IPR023795|interpro:IPR023796|interpro:IPR033829|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P01008|rcsb pdb:1ANT|rcsb pdb:1ATH|rcsb pdb:1AZX|rcsb pdb:1BR8|rcsb pdb:1DZG|rcsb pdb:1DZH|rcsb pdb:1E03|rcsb pdb:1E04|rcsb pdb:1E05|rcsb pdb:1JVQ|rcsb pdb:1LK6|rcsb pdb:1NQ9|rcsb pdb:1OYH|rcsb pdb:1R1L|rcsb pdb:1SR5|rcsb pdb:1T1F|rcsb pdb:1TB6|rcsb pdb:2ANT|rcsb pdb:2B4X|rcsb pdb:2B5T|rcsb pdb:2BEH|rcsb pdb:2GD4|rcsb pdb:2HIJ|rcsb pdb:2ZNH|rcsb pdb:3EVJ|rcsb pdb:3KCG|rcsb pdb:4EB1|reactome:R-HSA-140837|reactome:R-HSA-140875|reactome:R-HSA-381426|reactome:R-HSA-8957275|dip:DIP-38009N - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:71DYqPEISrr06/kbSTCdA3J23NU9606 rogid:XiPmXyU7CpPTgDR3dPnKeJEItJg9606 rigid:NHmJE13LRwF1tVv2JQWOJLD+sCc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNL4 uniprotkb:P04196 intact:EBI-2866661|uniprotkb:Q9H3J0|uniprotkb:Q96E15|uniprotkb:Q4VBQ6|uniprotkb:D3DUR8|uniprotkb:A4KYM4|uniprotkb:Q0EF62|uniprotkb:Q0EF63|uniprotkb:A4KYM6|ensembl:ENSP00000380024 intact:EBI-3915012|uniprotkb:B9EK35|uniprotkb:D3DNU7|ensembl:ENSP00000232003 psi-mi:ing4_human(display_long)|uniprotkb:ING4(gene name)|psi-mi:ING4(display_short)|uniprotkb:p29ING4(gene name synonym)|uniprotkb:My036(orf name) psi-mi:hrg_human(display_long)|uniprotkb:HRG(gene name)|psi-mi:HRG(display_short)|uniprotkb:Histidine-proline-rich glycoprotein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479510|imex:IM-26985-97 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001121054.1|refseq:NP_001121055.1|refseq:NP_001121056.1|refseq:NP_001121057.1|refseq:NP_001121058.1|refseq:NP_057246.2|dip:DIP-42222N|ensembl:ENSG00000111653(gene)|ensembl:ENST00000396807(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006473"(protein acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|interpro:IPR028651|mint:Q9UNL4|rcsb pdb:2K1J|rcsb pdb:2M1R|rcsb pdb:2PNX|rcsb pdb:2VNF|rcsb pdb:4AFL|reactome:R-HSA-3214847|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028638 refseq:NP_000403.1|ensembl:ENSG00000113905(gene)|ensembl:ENST00000232003(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0002839"(positive regulation of immune response to tumor cell)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0008201"(heparin binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010543"(regulation of platelet activation)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0015886"(heme transport)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0020037"(heme binding)|go:"GO:0030168"(platelet activation)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0033629"(negative regulation of cell adhesion mediated by integrin)|go:"GO:0036019"(endolysosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051838"(cytolysis by host of symbiont cells)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|go:"GO:2000504"(positive regulation of blood vessel remodeling)|go:"GO:2001027"(negative regulation of endothelial cell chemotaxis)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|mint:P04196|reactome:R-HSA-114608|reactome:R-HSA-75205|go:"GO:0043254"(regulation of protein-containing complex assembly)|dip:DIP-47264N - - comment:"author score: 28" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:71DYqPEISrr06/kbSTCdA3J23NU9606 rogid:o/MnMkd+IKLRtprrFoOapUuoVEs9606 rigid:NHmJE13LRwF1tVv2JQWOJLD+sCc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNL4 uniprotkb:Q9NQC1 intact:EBI-2866661|uniprotkb:Q9H3J0|uniprotkb:Q96E15|uniprotkb:Q4VBQ6|uniprotkb:D3DUR8|uniprotkb:A4KYM4|uniprotkb:Q0EF62|uniprotkb:Q0EF63|uniprotkb:A4KYM6|ensembl:ENSP00000380024 intact:EBI-2796167|uniprotkb:D3DQA3|uniprotkb:Q8TEK0|uniprotkb:Q92513|uniprotkb:Q6IE80|uniprotkb:Q96GQ6|ensembl:ENSP00000378451 psi-mi:ing4_human(display_long)|uniprotkb:ING4(gene name)|psi-mi:ING4(display_short)|uniprotkb:p29ING4(gene name synonym)|uniprotkb:My036(orf name) psi-mi:jade2_human(display_long)|uniprotkb:JADE2(gene name)|psi-mi:JADE2(display_short)|uniprotkb:Jade family PHD finger protein 2(gene name synonym)|uniprotkb:KIAA0239(gene name synonym)|uniprotkb:PHD finger protein 15(gene name synonym)|uniprotkb:PHF15(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479510|imex:IM-26985-97 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001121054.1|refseq:NP_001121055.1|refseq:NP_001121056.1|refseq:NP_001121057.1|refseq:NP_001121058.1|refseq:NP_057246.2|dip:DIP-42222N|ensembl:ENSG00000111653(gene)|ensembl:ENST00000396807(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006473"(protein acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|interpro:IPR028651|mint:Q9UNL4|rcsb pdb:2K1J|rcsb pdb:2M1R|rcsb pdb:2PNX|rcsb pdb:2VNF|rcsb pdb:4AFL|reactome:R-HSA-3214847|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028638 refseq:NP_056103.4|refseq:NP_001295072.1|refseq:NP_001276913.1|refseq:NP_001276914.1|ensembl:ENSG00000043143(gene)|ensembl:ENST00000395003(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR039548|interpro:IPR039549|mint:Q9NQC1|reactome:R-HSA-3214847 - - comment:"author score: 38" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:71DYqPEISrr06/kbSTCdA3J23NU9606 rogid:6HE0lz0S6SEAjJGunkR271uFfZQ9606 rigid:NHmJE13LRwF1tVv2JQWOJLD+sCc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNL4 uniprotkb:Q6IE81 intact:EBI-2866661|uniprotkb:Q9H3J0|uniprotkb:Q96E15|uniprotkb:Q4VBQ6|uniprotkb:D3DUR8|uniprotkb:A4KYM4|uniprotkb:Q0EF62|uniprotkb:Q0EF63|uniprotkb:A4KYM6|ensembl:ENSP00000380024 intact:EBI-954672|uniprotkb:Q4W5D5|uniprotkb:Q6ZSL7|uniprotkb:Q8NC41|uniprotkb:Q96JL8|uniprotkb:Q96SQ1|uniprotkb:Q9H692|uniprotkb:D3DNY0|uniprotkb:D3DNY1|ensembl:ENSP00000226319|ensembl:ENSP00000425730|ensembl:ENSP00000482212|ensembl:ENSP00000483219 psi-mi:ing4_human(display_long)|uniprotkb:ING4(gene name)|psi-mi:ING4(display_short)|uniprotkb:p29ING4(gene name synonym)|uniprotkb:My036(orf name) psi-mi:jade1_human(display_long)|uniprotkb:JADE1(gene name)|psi-mi:JADE1(display_short)|uniprotkb:Jade family PHD finger protein 1(gene name synonym)|uniprotkb:KIAA1807(gene name synonym)|uniprotkb:PHD finger protein 17(gene name synonym)|uniprotkb:PHF17(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479510|imex:IM-26985-97 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001121054.1|refseq:NP_001121055.1|refseq:NP_001121056.1|refseq:NP_001121057.1|refseq:NP_001121058.1|refseq:NP_057246.2|dip:DIP-42222N|ensembl:ENSG00000111653(gene)|ensembl:ENST00000396807(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006473"(protein acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|interpro:IPR028651|mint:Q9UNL4|rcsb pdb:2K1J|rcsb pdb:2M1R|rcsb pdb:2PNX|rcsb pdb:2VNF|rcsb pdb:4AFL|reactome:R-HSA-3214847|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028638 refseq:NP_079176.2|refseq:NP_955352.1|refseq:NP_001274372.1|refseq:NP_001274366.1|refseq:NP_001274368.1|refseq:NP_001274369.1|refseq:NP_001274370.1|refseq:NP_001274371.1|ensembl:ENSG00000077684(gene)|ensembl:ENST00000226319(transcript)|ensembl:ENST00000512960(transcript)|ensembl:ENST00000610919(transcript)|ensembl:ENST00000611140(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR039546|mint:Q6IE81|reactome:R-HSA-3214847|refseq:XP_005263289.1 - - comment:"author score: 49" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:71DYqPEISrr06/kbSTCdA3J23NU9606 rogid:brla9icZHYnZBj+2WtExolD2Z489606 rigid:NHmJE13LRwF1tVv2JQWOJLD+sCc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNL4 uniprotkb:P23527 intact:EBI-2866661|uniprotkb:Q9H3J0|uniprotkb:Q96E15|uniprotkb:Q4VBQ6|uniprotkb:D3DUR8|uniprotkb:A4KYM4|uniprotkb:Q0EF62|uniprotkb:Q0EF63|uniprotkb:A4KYM6|ensembl:ENSP00000380024 intact:EBI-1642161|uniprotkb:Q3KPI7|uniprotkb:Q8TCV6|ensembl:ENSP00000477527 psi-mi:ing4_human(display_long)|uniprotkb:ING4(gene name)|psi-mi:ING4(display_short)|uniprotkb:p29ING4(gene name synonym)|uniprotkb:My036(orf name) psi-mi:h2b1o_human(display_long)|uniprotkb:H2BC17(gene name)|psi-mi:H2BC17(display_short)|uniprotkb:H2B-clustered histone 17(gene name synonym)|uniprotkb:H2BFH(gene name synonym)|uniprotkb:H2BFN(gene name synonym)|uniprotkb:HIST1H2BO(gene name synonym)|uniprotkb:Histone H2B.2(gene name synonym)|uniprotkb:Histone H2B.n(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479510|imex:IM-26985-97 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001121054.1|refseq:NP_001121055.1|refseq:NP_001121056.1|refseq:NP_001121057.1|refseq:NP_001121058.1|refseq:NP_057246.2|dip:DIP-42222N|ensembl:ENSG00000111653(gene)|ensembl:ENST00000396807(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006473"(protein acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|interpro:IPR028651|mint:Q9UNL4|rcsb pdb:2K1J|rcsb pdb:2M1R|rcsb pdb:2PNX|rcsb pdb:2VNF|rcsb pdb:4AFL|reactome:R-HSA-3214847|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028638 refseq:NP_003518.2|ensembl:ENSG00000274641(gene)|ensembl:ENST00000616182(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P23527|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - comment:"author score: 57" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:71DYqPEISrr06/kbSTCdA3J23NU9606 rogid:vetsoCf1s6GUePoGq1wMLwz8obg9606 rigid:NHmJE13LRwF1tVv2JQWOJLD+sCc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNL4 uniprotkb:Q8WYB5 intact:EBI-2866661|uniprotkb:Q9H3J0|uniprotkb:Q96E15|uniprotkb:Q4VBQ6|uniprotkb:D3DUR8|uniprotkb:A4KYM4|uniprotkb:Q0EF62|uniprotkb:Q0EF63|uniprotkb:A4KYM6|ensembl:ENSP00000380024 intact:EBI-948029|uniprotkb:O15087|uniprotkb:Q86Y05|uniprotkb:Q8WU81|uniprotkb:Q9UKW2|uniprotkb:Q9UKW3|uniprotkb:Q9UKX0|ensembl:ENSP00000287239|ensembl:ENSP00000486595|ensembl:ENSP00000497166|ensembl:ENSP00000497352|ensembl:ENSP00000497718|ensembl:ENSP00000497841 psi-mi:ing4_human(display_long)|uniprotkb:ING4(gene name)|psi-mi:ING4(display_short)|uniprotkb:p29ING4(gene name synonym)|uniprotkb:My036(orf name) psi-mi:kat6b_human(display_long)|uniprotkb:MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4(gene name synonym)|uniprotkb:Histone acetyltransferase MOZ2(gene name synonym)|uniprotkb:Monocytic leukemia zinc finger protein-related factor(gene name synonym)|uniprotkb:KAT6B(gene name)|psi-mi:KAT6B(display_short)|uniprotkb:MYST4(gene name synonym)|uniprotkb:KIAA0383(gene name synonym)|uniprotkb:MORF(gene name synonym)|uniprotkb:MOZ2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479510|imex:IM-26985-97 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001121054.1|refseq:NP_001121055.1|refseq:NP_001121056.1|refseq:NP_001121057.1|refseq:NP_001121058.1|refseq:NP_057246.2|dip:DIP-42222N|ensembl:ENSG00000111653(gene)|ensembl:ENST00000396807(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006473"(protein acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|interpro:IPR028651|mint:Q9UNL4|rcsb pdb:2K1J|rcsb pdb:2M1R|rcsb pdb:2PNX|rcsb pdb:2VNF|rcsb pdb:4AFL|reactome:R-HSA-3214847|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028638 refseq:NP_036462.2|refseq:NP_001243397.1|refseq:NP_001243398.1|refseq:XP_005269721.1|ensembl:ENSP00000287239|ensembl:ENST00000372711|ensembl:ENSP00000361796|ensembl:ENST00000372714|ensembl:ENSP00000361799|ensembl:ENST00000372724|ensembl:ENSP00000361809|ensembl:ENST00000372725|ensembl:ENSP00000361810|ensembl:ENST00000628038|ensembl:ENSP00000485896|ensembl:ENST00000628523|ensembl:ENSP00000487238|ensembl:ENST00000629233|ensembl:ENSP00000487219|ensembl:ENST00000629879|ensembl:ENSP00000486731|ensembl:ENSP00000486595|ensembl:ENSP00000497352|ensembl:ENSP00000497718|ensembl:ENSP00000497841|ensembl:ENST00000648892|ensembl:ENSP00000497048|ensembl:ENST00000649006|ensembl:ENSP00000498139|ensembl:ENSP00000497166|ensembl:ENST00000649574|ensembl:ENSP00000497416|ensembl:ENST00000650575|ensembl:ENSP00000497453|refseq:XP_016871489.1|refseq:XP_016871490.1|refseq:XP_016871491.1|refseq:XP_016871492.1|refseq:XP_016871494.1|refseq:XP_016871495.1|refseq:XP_016871496.1|refseq:XP_016871497.1|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR005818(Histone H1/H5)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR019787|interpro:IPR036388|interpro:IPR036390|interpro:IPR040706|mint:Q8WYB5|interpro:IPR001965(Zinc finger, PHD-type)|rcsb pdb:5U2J|rcsb pdb:6OIE|reactome:R-HSA-3214847|ensembl:ENSG00000281813(gene)|ensembl:ENST00000287239(transcript)|ensembl:ENST00000630001(transcript)|ensembl:ENST00000647630(transcript)|ensembl:ENST00000648605(transcript)|ensembl:ENST00000648725(transcript)|ensembl:ENST00000649463(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|ensembl:ENSG00000156650(gene)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex) - - comment:"author score: 61" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:71DYqPEISrr06/kbSTCdA3J23NU9606 rogid:SQZ29f1Wqak9s8f4A1mrKmfToU09606 rigid:NHmJE13LRwF1tVv2JQWOJLD+sCc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNL4 uniprotkb:Q92794 intact:EBI-2866661|uniprotkb:Q9H3J0|uniprotkb:Q96E15|uniprotkb:Q4VBQ6|uniprotkb:D3DUR8|uniprotkb:A4KYM4|uniprotkb:Q0EF62|uniprotkb:Q0EF63|uniprotkb:A4KYM6|ensembl:ENSP00000380024 intact:EBI-948013|intact:EBI-1048839|uniprotkb:Q76L81|ensembl:ENSP00000265713|ensembl:ENSP00000380136 psi-mi:ing4_human(display_long)|uniprotkb:ING4(gene name)|psi-mi:ING4(display_short)|uniprotkb:p29ING4(gene name synonym)|uniprotkb:My036(orf name) psi-mi:kat6a_human(display_long)|uniprotkb:KAT6A(gene name)|psi-mi:KAT6A(display_short)|uniprotkb:MOZ(gene name synonym)|uniprotkb:RUNXBP2(gene name synonym)|uniprotkb:ZNF220(gene name synonym)|uniprotkb:MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3(gene name synonym)|uniprotkb:Runt-related transcription factor-binding protein 2(gene name synonym)|uniprotkb:Monocytic leukemia zinc finger protein(gene name synonym)|uniprotkb:Zinc finger protein 220(gene name synonym)|uniprotkb:MYST3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479510|imex:IM-26985-97 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001121054.1|refseq:NP_001121055.1|refseq:NP_001121056.1|refseq:NP_001121057.1|refseq:NP_001121058.1|refseq:NP_057246.2|dip:DIP-42222N|ensembl:ENSG00000111653(gene)|ensembl:ENST00000396807(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006473"(protein acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|interpro:IPR028651|mint:Q9UNL4|rcsb pdb:2K1J|rcsb pdb:2M1R|rcsb pdb:2PNX|rcsb pdb:2VNF|rcsb pdb:4AFL|reactome:R-HSA-3214847|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028638 refseq:NP_006757.2|ensembl:ENSP00000265713|ensembl:ENSP00000380136|refseq:XP_016869352.1|refseq:XP_016869353.1|ensembl:ENSG00000083168(gene)|ensembl:ENST00000265713(transcript)|ensembl:ENST00000396930(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006323"(DNA packaging)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006473"(protein acetylation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|go:"GO:0090398"(cellular senescence)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR005818(Histone H1/H5)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR019787|interpro:IPR031280|interpro:IPR036388|interpro:IPR036390|interpro:IPR040706|mint:Q92794|rcsb pdb:1M36|rcsb pdb:2LN0|rcsb pdb:2OZU|rcsb pdb:2RC4|rcsb pdb:3V43|rcsb pdb:4LJN|rcsb pdb:4LK9|rcsb pdb:4LKA|rcsb pdb:4LLB|rcsb pdb:5B75|rcsb pdb:5B76|rcsb pdb:5B77|rcsb pdb:5B78|rcsb pdb:6LSB|reactome:R-HSA-3214847|reactome:R-HSA-6804758 - - comment:"author score: 67" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:71DYqPEISrr06/kbSTCdA3J23NU9606 rogid:jPgi03a1G13Lv1IjZOz9vz1FvcY9606 rigid:NHmJE13LRwF1tVv2JQWOJLD+sCc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNL4 uniprotkb:P55201 intact:EBI-2866661|uniprotkb:Q9H3J0|uniprotkb:Q96E15|uniprotkb:Q4VBQ6|uniprotkb:D3DUR8|uniprotkb:A4KYM4|uniprotkb:Q0EF62|uniprotkb:Q0EF63|uniprotkb:A4KYM6|ensembl:ENSP00000380024 intact:EBI-2837428|uniprotkb:Q9UHI0|uniprotkb:Q8TCM6|uniprotkb:B4DEZ6|uniprotkb:Q7Z6E0|ensembl:ENSP00000507469 psi-mi:ing4_human(display_long)|uniprotkb:ING4(gene name)|psi-mi:ING4(display_short)|uniprotkb:p29ING4(gene name synonym)|uniprotkb:My036(orf name) psi-mi:brpf1_human(display_long)|uniprotkb:BRPF1(gene name)|psi-mi:BRPF1(display_short)|uniprotkb:BR140(gene name synonym)|uniprotkb:Bromodomain and PHD finger-containing protein 1(gene name synonym)|uniprotkb:Protein Br140(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479510|imex:IM-26985-97 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001121054.1|refseq:NP_001121055.1|refseq:NP_001121056.1|refseq:NP_001121057.1|refseq:NP_001121058.1|refseq:NP_057246.2|dip:DIP-42222N|ensembl:ENSG00000111653(gene)|ensembl:ENST00000396807(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006473"(protein acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|interpro:IPR028651|mint:Q9UNL4|rcsb pdb:2K1J|rcsb pdb:2M1R|rcsb pdb:2PNX|rcsb pdb:2VNF|rcsb pdb:4AFL|reactome:R-HSA-3214847|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028638 refseq:NP_001003694.1|refseq:NP_004625.2|refseq:NP_001305978.1|refseq:NP_001305979.1|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042008|interpro:IPR042061|mint:P55201|rcsb pdb:2D9E|rcsb pdb:2RS9|rcsb pdb:2X35|rcsb pdb:2X4W|rcsb pdb:2X4X|interpro:IPR001487(Bromodomain)|rcsb pdb:2X4Y|rcsb pdb:3MO8|rcsb pdb:4LC2|rcsb pdb:4QYD|rcsb pdb:4QYL|rcsb pdb:4UYE|rcsb pdb:5C6S|rcsb pdb:5C7N|rcsb pdb:5C85|rcsb pdb:5C87|rcsb pdb:5C89|rcsb pdb:5D7X|rcsb pdb:5DY7|rcsb pdb:5DYA|rcsb pdb:5DYC|rcsb pdb:5E3D|rcsb pdb:5E3G|rcsb pdb:5EM3|rcsb pdb:5EPR|rcsb pdb:5EPS|rcsb pdb:3L42|rcsb pdb:5EQ1|rcsb pdb:5ERC|ensembl:ENSG00000156983(gene)|ensembl:ENST00000683743(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010698"(acetyltransferase activator activity)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|rcsb pdb:5ETB|rcsb pdb:5ETD|rcsb pdb:5EV9|rcsb pdb:5EVA|rcsb pdb:5OWE|rcsb pdb:5EWC|rcsb pdb:5T4U|rcsb pdb:5EWD|rcsb pdb:5EWH|rcsb pdb:5EWV|rcsb pdb:5EWW|rcsb pdb:5FFV|rcsb pdb:5FFW|rcsb pdb:5FFY|rcsb pdb:5FG4|rcsb pdb:5FG5|rcsb pdb:5G4R|rcsb pdb:5G4S|rcsb pdb:5MWG|rcsb pdb:5MWH|rcsb pdb:5MWZ|rcsb pdb:5MYG|rcsb pdb:5O4S|rcsb pdb:5O4T|rcsb pdb:5O55|rcsb pdb:5O5A|rcsb pdb:5O5F|rcsb pdb:5O5H|rcsb pdb:5OV8|rcsb pdb:5OWA|rcsb pdb:5OWB|rcsb pdb:6EKQ|rcsb pdb:6U04|rcsb pdb:7C4I|reactome:R-HSA-3214847|reactome:R-HSA-6804758|rcsb pdb:5T4V|dip:DIP-59001N - - comment:"author score: 71" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:71DYqPEISrr06/kbSTCdA3J23NU9606 rogid:+sZdYbyk1/VdG0qCF2CL3h1liVw9606 rigid:NHmJE13LRwF1tVv2JQWOJLD+sCc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNL4 uniprotkb:Q92613 intact:EBI-2866661|uniprotkb:Q9H3J0|uniprotkb:Q96E15|uniprotkb:Q4VBQ6|uniprotkb:D3DUR8|uniprotkb:A4KYM4|uniprotkb:Q0EF62|uniprotkb:Q0EF63|uniprotkb:A4KYM6|ensembl:ENSP00000380024 intact:EBI-10278909|uniprotkb:Q6IE79|ensembl:ENSP00000479377|ensembl:ENSP00000481850 psi-mi:ing4_human(display_long)|uniprotkb:ING4(gene name)|psi-mi:ING4(display_short)|uniprotkb:p29ING4(gene name synonym)|uniprotkb:My036(orf name) psi-mi:jade3_human(display_long)|uniprotkb:JADE3(gene name)|psi-mi:JADE3(display_short)|uniprotkb:Jade family PHD finger protein 3(gene name synonym)|uniprotkb:KIAA0215(gene name synonym)|uniprotkb:PHD finger protein 16(gene name synonym)|uniprotkb:PHF16(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479510|imex:IM-26985-97 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001121054.1|refseq:NP_001121055.1|refseq:NP_001121056.1|refseq:NP_001121057.1|refseq:NP_001121058.1|refseq:NP_057246.2|dip:DIP-42222N|ensembl:ENSG00000111653(gene)|ensembl:ENST00000396807(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006473"(protein acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|interpro:IPR028651|mint:Q9UNL4|rcsb pdb:2K1J|rcsb pdb:2M1R|rcsb pdb:2PNX|rcsb pdb:2VNF|rcsb pdb:4AFL|reactome:R-HSA-3214847|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028638 refseq:NP_001070913.1|refseq:NP_055550.1|ensembl:ENSG00000102221(gene)|ensembl:ENST00000611250(transcript)|ensembl:ENST00000614628(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR039550|mint:Q92613|reactome:R-HSA-3214847 - - comment:"author score: 77" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:71DYqPEISrr06/kbSTCdA3J23NU9606 rogid:OUQwlVF1k9d+/zAq0GlCmjOh+8s9606 rigid:NHmJE13LRwF1tVv2JQWOJLD+sCc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNL4 uniprotkb:Q9ULD4 intact:EBI-2866661|uniprotkb:Q9H3J0|uniprotkb:Q96E15|uniprotkb:Q4VBQ6|uniprotkb:D3DUR8|uniprotkb:A4KYM4|uniprotkb:Q0EF62|uniprotkb:Q0EF63|uniprotkb:A4KYM6|ensembl:ENSP00000380024 intact:EBI-1753470|uniprotkb:A6NJE2|uniprotkb:Q5R3K8|ensembl:ENSP00000350267|intact:EBI-2860074|uniprotkb:A6ND56|uniprotkb:B7ZLN5|uniprotkb:E7EX85|uniprotkb:Q17RB6 psi-mi:ing4_human(display_long)|uniprotkb:ING4(gene name)|psi-mi:ING4(display_short)|uniprotkb:p29ING4(gene name synonym)|uniprotkb:My036(orf name) psi-mi:brpf3_human(display_long)|uniprotkb:BRPF3(gene name)|psi-mi:BRPF3(display_short)|uniprotkb:KIAA1286(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479510|imex:IM-26985-97 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001121054.1|refseq:NP_001121055.1|refseq:NP_001121056.1|refseq:NP_001121057.1|refseq:NP_001121058.1|refseq:NP_057246.2|dip:DIP-42222N|ensembl:ENSG00000111653(gene)|ensembl:ENST00000396807(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006473"(protein acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|interpro:IPR028651|mint:Q9UNL4|rcsb pdb:2K1J|rcsb pdb:2M1R|rcsb pdb:2PNX|rcsb pdb:2VNF|rcsb pdb:4AFL|reactome:R-HSA-3214847|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028638 refseq:XP_011512791.1|refseq:XP_005249067.1|refseq:XP_005249068.1|refseq:NP_056510.2|ensembl:ENSG00000096070(gene)|ensembl:ENST00000357641(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042005|mint:Q9ULD4|rcsb pdb:3PFS|reactome:R-HSA-114608|reactome:R-HSA-3214847|reactome:R-HSA-6804758|interpro:IPR018359 - - comment:"author score: 90" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:71DYqPEISrr06/kbSTCdA3J23NU9606 rogid:CgyLb1z0upVoKfJxtzvybQ6NAkE9606 rigid:NHmJE13LRwF1tVv2JQWOJLD+sCc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNL4 uniprotkb:O95251 intact:EBI-2866661|uniprotkb:Q9H3J0|uniprotkb:Q96E15|uniprotkb:Q4VBQ6|uniprotkb:D3DUR8|uniprotkb:A4KYM4|uniprotkb:Q0EF62|uniprotkb:Q0EF63|uniprotkb:A4KYM6|ensembl:ENSP00000380024 intact:EBI-473199|uniprotkb:B3KN74|uniprotkb:B4DFB4|uniprotkb:B4DFE0|uniprotkb:B4DF85|uniprotkb:B4DGY4|uniprotkb:E7ER15|uniprotkb:G5E9K7|intact:EBI-10986821|ensembl:ENSP00000259021 psi-mi:ing4_human(display_long)|uniprotkb:ING4(gene name)|psi-mi:ING4(display_short)|uniprotkb:p29ING4(gene name synonym)|uniprotkb:My036(orf name) psi-mi:kat7_human(display_long)|uniprotkb:KAT7(gene name)|psi-mi:KAT7(display_short)|uniprotkb:HBO1(gene name synonym)|uniprotkb:HBOa(gene name synonym)|uniprotkb:MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2(gene name synonym)|uniprotkb:Histone acetyltransferase binding to ORC1(gene name synonym)|uniprotkb:MYST2(gene name synonym)|uniprotkb:Lysine acetyltransferase 7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479510|imex:IM-26985-97 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001121054.1|refseq:NP_001121055.1|refseq:NP_001121056.1|refseq:NP_001121057.1|refseq:NP_001121058.1|refseq:NP_057246.2|dip:DIP-42222N|ensembl:ENSG00000111653(gene)|ensembl:ENST00000396807(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006473"(protein acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|interpro:IPR028651|mint:Q9UNL4|rcsb pdb:2K1J|rcsb pdb:2M1R|rcsb pdb:2PNX|rcsb pdb:2VNF|rcsb pdb:4AFL|reactome:R-HSA-3214847|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028638 refseq:NP_001186084.1|refseq:NP_001186085.1|refseq:NP_001186086.1|refseq:NP_001186087.1|refseq:NP_008998.1|dip:DIP-29697N|ensembl:ENSG00000136504(gene)|ensembl:ENST00000259021(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031098"(stress-activated protein kinase signaling cascade)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0036409"(histone H3-K14 acetyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0072708"(response to sorbitol)|go:"GO:0072710"(response to hydroxyurea)|go:"GO:0072716"(response to actinomycin D)|go:"GO:0072720"(response to dithiothreitol)|go:"GO:0072739"(response to anisomycin)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:0090734"(site of DNA damage)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902035"(positive regulation of hematopoietic stem cell proliferation)|go:"GO:2000819"(regulation of nucleotide-excision repair)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR036060|interpro:IPR036388|interpro:IPR040706|mint:O95251|rcsb pdb:5GK9|rcsb pdb:6MAJ|rcsb pdb:6MAK|reactome:R-HSA-3214847 - - comment:"author score: 151" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:71DYqPEISrr06/kbSTCdA3J23NU9606 rogid:K27pgvPEe1/+rZXYUkPfMY7PZMs9606 rigid:NHmJE13LRwF1tVv2JQWOJLD+sCc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNL4 uniprotkb:Q9HAF1 intact:EBI-2866661|uniprotkb:Q9H3J0|uniprotkb:Q96E15|uniprotkb:Q4VBQ6|uniprotkb:D3DUR8|uniprotkb:A4KYM4|uniprotkb:Q0EF62|uniprotkb:Q0EF63|uniprotkb:A4KYM6|ensembl:ENSP00000380024 intact:EBI-399266|uniprotkb:B1AK64|uniprotkb:Q4F967|uniprotkb:Q7Z311|uniprotkb:Q86WE3|ensembl:ENSP00000296214 psi-mi:ing4_human(display_long)|uniprotkb:ING4(gene name)|psi-mi:ING4(display_short)|uniprotkb:p29ING4(gene name synonym)|uniprotkb:My036(orf name) psi-mi:eaf6_human(display_long)|uniprotkb:Sarcoma antigen NY-SAR-91(gene name synonym)|uniprotkb:MEAF6(gene name)|psi-mi:MEAF6(display_short)|uniprotkb:EAF6(gene name synonym)|uniprotkb:Esa1-associated factor 6 homolog(gene name synonym)|uniprotkb:C1orf149(gene name synonym)|uniprotkb:CENP-28(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479510|imex:IM-26985-97 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001121054.1|refseq:NP_001121055.1|refseq:NP_001121056.1|refseq:NP_001121057.1|refseq:NP_001121058.1|refseq:NP_057246.2|dip:DIP-42222N|ensembl:ENSG00000111653(gene)|ensembl:ENST00000396807(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006473"(protein acetylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|interpro:IPR028651|mint:Q9UNL4|rcsb pdb:2K1J|rcsb pdb:2M1R|rcsb pdb:2PNX|rcsb pdb:2VNF|rcsb pdb:4AFL|reactome:R-HSA-3214847|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028638 refseq:NP_001257804.1|refseq:NP_073593.2|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|go:"GO:1990467"(NuA3a histone acetyltransferase complex)|go:"GO:1990468"(NuA3b histone acetyltransferase complex)|interpro:IPR015418(Histone H4 acetyltransferase, NuA4 complex, Eaf6)|mint:Q9HAF1|reactome:R-HSA-3214847|reactome:R-HSA-6804758|ensembl:ENSG00000163875(gene)|ensembl:ENST00000296214(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|refseq:NP_001257805.1 - - comment:"author score: 216" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:71DYqPEISrr06/kbSTCdA3J23NU9606 rogid:v0eU3uwnLihcUQhLKYma3WIhofk9606 rigid:NHmJE13LRwF1tVv2JQWOJLD+sCc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C870 uniprotkb:O00483 intact:EBI-9090173|uniprotkb:Q9UKV7|uniprotkb:Q8TB10|uniprotkb:A5D6V5|uniprotkb:Q59GF9|uniprotkb:O95712|ensembl:ENSP00000380467 intact:EBI-1049381|uniprotkb:Q6FHN5|uniprotkb:A4D109|ensembl:ENSP00000339720 psi-mi:jmjd7_human(display_long)|uniprotkb:Jumonji domain-containing protein 7(gene name synonym)|uniprotkb:JMJD7(gene name)|psi-mi:JMJD7(display_short)|uniprotkb:JmjC domain-containing protein 7(gene name synonym)|uniprotkb:"L-lysine (3S)-hydroxylase JMJD7"(gene name synonym) psi-mi:ndua4_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase MLRQ subunit(gene name synonym)|uniprotkb:Complex I-MLRQ(gene name synonym)|uniprotkb:NDUFA4(gene name)|psi-mi:NDUFA4(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479750|imex:IM-26985-405 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001108104.1|ensembl:ENST00000397299(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR041667|mint:P0C870|rcsb pdb:5NFN|ensembl:ENSG00000243789(gene)|rcsb pdb:5NFO refseq:NP_002480.1|ensembl:ENSG00000189043(gene)|ensembl:ENST00000339600(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1904960"(positive regulation of cytochrome-c oxidase activity)|interpro:IPR010530(B12D)|mint:O00483|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nEpqkRxJEXiQhXjje3BEwXVxKKE9606 rogid:TnrYlkH8abl42/yGsvfc8Bh6Mu09606 rigid:ftgA8ADgZiAseiaA3T+XmReI7nc false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C870 uniprotkb:P50991 intact:EBI-9090173|uniprotkb:Q9UKV7|uniprotkb:Q8TB10|uniprotkb:A5D6V5|uniprotkb:Q59GF9|uniprotkb:O95712|ensembl:ENSP00000380467 intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958 psi-mi:jmjd7_human(display_long)|uniprotkb:Jumonji domain-containing protein 7(gene name synonym)|uniprotkb:JMJD7(gene name)|psi-mi:JMJD7(display_short)|uniprotkb:JmjC domain-containing protein 7(gene name synonym)|uniprotkb:"L-lysine (3S)-hydroxylase JMJD7"(gene name synonym) psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479750|imex:IM-26985-405 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001108104.1|ensembl:ENST00000397299(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR041667|mint:P0C870|rcsb pdb:5NFN|ensembl:ENSG00000243789(gene)|rcsb pdb:5NFO refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nEpqkRxJEXiQhXjje3BEwXVxKKE9606 rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606 rigid:ftgA8ADgZiAseiaA3T+XmReI7nc false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C870 uniprotkb:P49368 intact:EBI-9090173|uniprotkb:Q9UKV7|uniprotkb:Q8TB10|uniprotkb:A5D6V5|uniprotkb:Q59GF9|uniprotkb:O95712|ensembl:ENSP00000380467 intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688 psi-mi:jmjd7_human(display_long)|uniprotkb:Jumonji domain-containing protein 7(gene name synonym)|uniprotkb:JMJD7(gene name)|psi-mi:JMJD7(display_short)|uniprotkb:JmjC domain-containing protein 7(gene name synonym)|uniprotkb:"L-lysine (3S)-hydroxylase JMJD7"(gene name synonym) psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479750|imex:IM-26985-405 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001108104.1|ensembl:ENST00000397299(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR041667|mint:P0C870|rcsb pdb:5NFN|ensembl:ENSG00000243789(gene)|rcsb pdb:5NFO refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nEpqkRxJEXiQhXjje3BEwXVxKKE9606 rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606 rigid:ftgA8ADgZiAseiaA3T+XmReI7nc false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C870 uniprotkb:Q96CS3 intact:EBI-9090173|uniprotkb:Q9UKV7|uniprotkb:Q8TB10|uniprotkb:A5D6V5|uniprotkb:Q59GF9|uniprotkb:O95712|ensembl:ENSP00000380467 intact:EBI-1055805|uniprotkb:O94963|uniprotkb:Q8IUF2|uniprotkb:Q9BRP2|uniprotkb:Q9BVM7|ensembl:ENSP00000261942 psi-mi:jmjd7_human(display_long)|uniprotkb:Jumonji domain-containing protein 7(gene name synonym)|uniprotkb:JMJD7(gene name)|psi-mi:JMJD7(display_short)|uniprotkb:JmjC domain-containing protein 7(gene name synonym)|uniprotkb:"L-lysine (3S)-hydroxylase JMJD7"(gene name synonym) psi-mi:faf2_human(display_long)|uniprotkb:Protein ETEA(gene name synonym)|uniprotkb:FAF2(gene name)|psi-mi:FAF2(display_short)|uniprotkb:ETEA(gene name synonym)|uniprotkb:KIAA0887(gene name synonym)|uniprotkb:UBXD8(gene name synonym)|uniprotkb:UBXN3B(gene name synonym)|uniprotkb:UBX domain-containing protein 3B(gene name synonym)|uniprotkb:UBX domain-containing protein 8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479750|imex:IM-26985-405 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001108104.1|ensembl:ENST00000397299(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR041667|mint:P0C870|rcsb pdb:5NFN|ensembl:ENSG00000243789(gene)|rcsb pdb:5NFO refseq:NP_055428.1|ensembl:ENSP00000261942|ensembl:ENST00000261942(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034098"(VCP-NPL4-UFD1 AAA ATPase complex)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035473"(lipase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0055102"(lipase inhibitor activity)|interpro:IPR001012(UBX)|interpro:IPR006577(UAS)|interpro:IPR009060(UBA-like)|interpro:IPR029071|interpro:IPR036249|mint:Q96CS3|rcsb pdb:2DAM|reactome:R-HSA-6798695|reactome:R-HSA-8980692|ensembl:ENSG00000113194(gene)|dip:DIP-46261N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nEpqkRxJEXiQhXjje3BEwXVxKKE9606 rogid:GCm7BqDpwxDW1iABu0cShmWHtZQ9606 rigid:ftgA8ADgZiAseiaA3T+XmReI7nc false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C870 uniprotkb:P40227 intact:EBI-9090173|uniprotkb:Q9UKV7|uniprotkb:Q8TB10|uniprotkb:A5D6V5|uniprotkb:Q59GF9|uniprotkb:O95712|ensembl:ENSP00000380467 intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2 psi-mi:jmjd7_human(display_long)|uniprotkb:Jumonji domain-containing protein 7(gene name synonym)|uniprotkb:JMJD7(gene name)|psi-mi:JMJD7(display_short)|uniprotkb:JmjC domain-containing protein 7(gene name synonym)|uniprotkb:"L-lysine (3S)-hydroxylase JMJD7"(gene name synonym) psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479750|imex:IM-26985-405 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001108104.1|ensembl:ENST00000397299(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR041667|mint:P0C870|rcsb pdb:5NFN|ensembl:ENSG00000243789(gene)|rcsb pdb:5NFO refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nEpqkRxJEXiQhXjje3BEwXVxKKE9606 rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606 rigid:ftgA8ADgZiAseiaA3T+XmReI7nc false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C870 uniprotkb:P50990 intact:EBI-9090173|uniprotkb:Q9UKV7|uniprotkb:Q8TB10|uniprotkb:A5D6V5|uniprotkb:Q59GF9|uniprotkb:O95712|ensembl:ENSP00000380467 intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788 psi-mi:jmjd7_human(display_long)|uniprotkb:Jumonji domain-containing protein 7(gene name synonym)|uniprotkb:JMJD7(gene name)|psi-mi:JMJD7(display_short)|uniprotkb:JmjC domain-containing protein 7(gene name synonym)|uniprotkb:"L-lysine (3S)-hydroxylase JMJD7"(gene name synonym) psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479750|imex:IM-26985-405 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001108104.1|ensembl:ENST00000397299(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR041667|mint:P0C870|rcsb pdb:5NFN|ensembl:ENSG00000243789(gene)|rcsb pdb:5NFO refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nEpqkRxJEXiQhXjje3BEwXVxKKE9606 rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606 rigid:ftgA8ADgZiAseiaA3T+XmReI7nc false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C870 uniprotkb:Q99832 intact:EBI-9090173|uniprotkb:Q9UKV7|uniprotkb:Q8TB10|uniprotkb:A5D6V5|uniprotkb:Q59GF9|uniprotkb:O95712|ensembl:ENSP00000380467 intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091 psi-mi:jmjd7_human(display_long)|uniprotkb:Jumonji domain-containing protein 7(gene name synonym)|uniprotkb:JMJD7(gene name)|psi-mi:JMJD7(display_short)|uniprotkb:JmjC domain-containing protein 7(gene name synonym)|uniprotkb:"L-lysine (3S)-hydroxylase JMJD7"(gene name synonym) psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479750|imex:IM-26985-405 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001108104.1|ensembl:ENST00000397299(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR041667|mint:P0C870|rcsb pdb:5NFN|ensembl:ENSG00000243789(gene)|rcsb pdb:5NFO dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422 - - comment:"author score: 30" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nEpqkRxJEXiQhXjje3BEwXVxKKE9606 rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606 rigid:ftgA8ADgZiAseiaA3T+XmReI7nc false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0C870 uniprotkb:P78371 intact:EBI-9090173|uniprotkb:Q9UKV7|uniprotkb:Q8TB10|uniprotkb:A5D6V5|uniprotkb:Q59GF9|uniprotkb:O95712|ensembl:ENSP00000380467 intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300 psi-mi:jmjd7_human(display_long)|uniprotkb:Jumonji domain-containing protein 7(gene name synonym)|uniprotkb:JMJD7(gene name)|psi-mi:JMJD7(display_short)|uniprotkb:JmjC domain-containing protein 7(gene name synonym)|uniprotkb:"L-lysine (3S)-hydroxylase JMJD7"(gene name synonym) psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479750|imex:IM-26985-405 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001108104.1|ensembl:ENST00000397299(transcript)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0004497"(monooxygenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0018126"(protein hydroxylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR041667|mint:P0C870|rcsb pdb:5NFN|ensembl:ENSG00000243789(gene)|rcsb pdb:5NFO refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695 - - comment:"author score: 30" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nEpqkRxJEXiQhXjje3BEwXVxKKE9606 rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606 rigid:ftgA8ADgZiAseiaA3T+XmReI7nc false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6NYC1 uniprotkb:P35244 intact:EBI-8464037|uniprotkb:Q9Y4E2|uniprotkb:B4DGX1|uniprotkb:Q8IUM5|uniprotkb:B3KMN8|intact:MINT-3086431|uniprotkb:Q86VY0|ensembl:ENSP00000380750 intact:EBI-621428|ensembl:ENSP00000223129|ensembl:ENSP00000379914|uniprotkb:Q549U6|intact:EBI-1058317 psi-mi:jmjd6_human(display_long)|uniprotkb:PTDSR(gene name synonym)|uniprotkb:KIAA0585(gene name synonym)|uniprotkb:JMJD6(gene name)|psi-mi:JMJD6(display_short)|uniprotkb:Histone arginine demethylase JMJD6(gene name synonym)|uniprotkb:JmjC domain-containing protein 6(gene name synonym)|uniprotkb:Jumonji domain-containing protein 6(gene name synonym)|uniprotkb:Lysyl-hydroxylase JMJD6(gene name synonym)|uniprotkb:Peptide-lysine 5-dioxygenase JMJD6(gene name synonym)|uniprotkb:Phosphatidylserine receptor(gene name synonym)|uniprotkb:PSR(gene name synonym) psi-mi:rfa3_human(display_long)|uniprotkb:Replication factor A protein 3(gene name synonym)|uniprotkb:RPA3(gene name)|psi-mi:RPA3(display_short)|uniprotkb:REPA3(gene name synonym)|uniprotkb:RPA14(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479708|imex:IM-26985-329 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055982.2|refseq:NP_001074930.1|dip:DIP-60686N|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006482"(protein demethylation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0008380"(RNA splicing)|go:"GO:0018395"(peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine)|go:"GO:0005506"(iron ion binding)|go:"GO:0030324"(lung development)|go:"GO:0032451"(demethylase activity)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033746"(histone H3-methyl-arginine-2 demethylase activity)|go:"GO:0033749"(histone H3-methyl-arginine-3 demethylase activity)|go:"GO:0035513"(oxidative RNA demethylation)|go:"GO:0035515"(oxidative RNA demethylase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042116"(macrophage activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048821"(erythrocyte development)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070078"(histone H3-R2 demethylation)|go:"GO:0070079"(histone H4-R3 demethylation)|go:"GO:0070815"(peptidyl-lysine 5-dioxygenase activity)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0140537"(transcription regulator activator activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q6NYC1|rcsb pdb:3K2O|rcsb pdb:3LD8|rcsb pdb:3LDB|rcsb pdb:6BNH|go:"GO:0043654"(recognition of apoptotic cell)|rcsb pdb:6MEV|reactome:R-HSA-3214842|rcsb pdb:6GDY|ensembl:ENSG00000070495(gene)|ensembl:ENST00000397625(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding) go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0035861"(site of double-strand break)|ensembl:ENSG00000106399(gene)|go:"GO:0042127"(regulation of cell population proliferation)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013970(Replication factor A protein 3)|mint:P35244|rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|ensembl:ENST00000223129(transcript)|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|ensembl:ENST00000396682(transcript)|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|refseq:NP_002938.1|dip:DIP-24190N - comment:mint|comment:homomint|function:Arginine demethylase which demethylates histone H3 at 'Arg-3' and histone H4 at 'Arg-4'. Required for differentiation of multiple organs during embryogenesis. Probably acts as a key regulator of hematopoietic differentiation. Seems to be necessary for the regulation of macrophage cytokine responses comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:YbwfNgf/c4ug+02lkCn2C4tMLEI9606 rogid:hHO7MxGGHUjz30HXSBZd9cXOq6I9606 rigid:o3vXtnaFZ1GZUPqWYoaOaIPmqDA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6NYC1 uniprotkb:P49773 intact:EBI-8464037|uniprotkb:Q9Y4E2|uniprotkb:B4DGX1|uniprotkb:Q8IUM5|uniprotkb:B3KMN8|intact:MINT-3086431|uniprotkb:Q86VY0|ensembl:ENSP00000380750 intact:EBI-1054330|uniprotkb:Q9H5W8|ensembl:ENSP00000304229 psi-mi:jmjd6_human(display_long)|uniprotkb:PTDSR(gene name synonym)|uniprotkb:KIAA0585(gene name synonym)|uniprotkb:JMJD6(gene name)|psi-mi:JMJD6(display_short)|uniprotkb:Histone arginine demethylase JMJD6(gene name synonym)|uniprotkb:JmjC domain-containing protein 6(gene name synonym)|uniprotkb:Jumonji domain-containing protein 6(gene name synonym)|uniprotkb:Lysyl-hydroxylase JMJD6(gene name synonym)|uniprotkb:Peptide-lysine 5-dioxygenase JMJD6(gene name synonym)|uniprotkb:Phosphatidylserine receptor(gene name synonym)|uniprotkb:PSR(gene name synonym) psi-mi:hint1_human(display_long)|uniprotkb:Protein kinase C inhibitor 1(gene name synonym)|uniprotkb:Protein kinase C-interacting protein 1(gene name synonym)|uniprotkb:HINT1(gene name)|psi-mi:HINT1(display_short)|uniprotkb:HINT(gene name synonym)|uniprotkb:PKCI1(gene name synonym)|uniprotkb:PRKCNH1(gene name synonym)|uniprotkb:Desumoylating isopeptidase HINT1(gene name synonym)|uniprotkb:Histidine triad nucleotide-binding protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479708|imex:IM-26985-329 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055982.2|refseq:NP_001074930.1|dip:DIP-60686N|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006482"(protein demethylation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0008380"(RNA splicing)|go:"GO:0018395"(peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine)|go:"GO:0005506"(iron ion binding)|go:"GO:0030324"(lung development)|go:"GO:0032451"(demethylase activity)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033746"(histone H3-methyl-arginine-2 demethylase activity)|go:"GO:0033749"(histone H3-methyl-arginine-3 demethylase activity)|go:"GO:0035513"(oxidative RNA demethylation)|go:"GO:0035515"(oxidative RNA demethylase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042116"(macrophage activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048821"(erythrocyte development)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070078"(histone H3-R2 demethylation)|go:"GO:0070079"(histone H4-R3 demethylation)|go:"GO:0070815"(peptidyl-lysine 5-dioxygenase activity)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0140537"(transcription regulator activator activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q6NYC1|rcsb pdb:3K2O|rcsb pdb:3LD8|rcsb pdb:3LDB|rcsb pdb:6BNH|go:"GO:0043654"(recognition of apoptotic cell)|rcsb pdb:6MEV|reactome:R-HSA-3214842|rcsb pdb:6GDY|ensembl:ENSG00000070495(gene)|ensembl:ENST00000397625(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding) refseq:NP_005331.1|go:"GO:0016787"(hydrolase activity)|go:"GO:0043530"(adenosine 5'-monophosphoramidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|interpro:IPR001310("Histidine triad (HIT) protein")|interpro:IPR011146(Histidine triad-like motif)|interpro:IPR019808|interpro:IPR036265|mint:P49773|rcsb pdb:1AV5|rcsb pdb:1KPA|rcsb pdb:1KPB|rcsb pdb:1KPC|rcsb pdb:1KPE|rcsb pdb:1KPF|rcsb pdb:3TW2|ensembl:ENSG00000169567(gene)|ensembl:ENST00000304043(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000166"(nucleotide binding)|rcsb pdb:4EQE|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|rcsb pdb:4EQG|go:"GO:0005654"(nucleoplasm)|rcsb pdb:4EQH|rcsb pdb:4ZKL|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007165"(signal transduction)|go:"GO:0009154"(purine ribonucleotide catabolic process)|rcsb pdb:4ZKV|rcsb pdb:5ED3|rcsb pdb:5ED6|rcsb pdb:5EMT|rcsb pdb:5I2E|rcsb pdb:5I2F|rcsb pdb:5IPB|rcsb pdb:5IPC|rcsb pdb:5IPD|rcsb pdb:5IPE|rcsb pdb:5KLY|rcsb pdb:5KLZ|rcsb pdb:5KM0|rcsb pdb:5KM1|rcsb pdb:5KM2|rcsb pdb:5KM3|rcsb pdb:5KM4|rcsb pdb:5KM6|rcsb pdb:5KMA|rcsb pdb:5KMB|rcsb pdb:5KMC|rcsb pdb:5O8I|rcsb pdb:5WA8|rcsb pdb:5WA9|rcsb pdb:5WAA|rcsb pdb:6B42|rcsb pdb:6G9Z|rcsb pdb:6J53|rcsb pdb:6J58|rcsb pdb:6J5S|rcsb pdb:6J5Z|rcsb pdb:6J64|rcsb pdb:6J65|rcsb pdb:6N3V|rcsb pdb:6N3W|rcsb pdb:6N3X|rcsb pdb:6N3Y|rcsb pdb:6YQM - comment:mint|comment:homomint|function:Arginine demethylase which demethylates histone H3 at 'Arg-3' and histone H4 at 'Arg-4'. Required for differentiation of multiple organs during embryogenesis. Probably acts as a key regulator of hematopoietic differentiation. Seems to be necessary for the regulation of macrophage cytokine responses comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:YbwfNgf/c4ug+02lkCn2C4tMLEI9606 rogid:vXotU/cqS8hSHeBmCk30zSQ9k/E9606 rigid:o3vXtnaFZ1GZUPqWYoaOaIPmqDA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6NYC1 uniprotkb:P16402 intact:EBI-8464037|uniprotkb:Q9Y4E2|uniprotkb:B4DGX1|uniprotkb:Q8IUM5|uniprotkb:B3KMN8|intact:MINT-3086431|uniprotkb:Q86VY0|ensembl:ENSP00000380750 intact:EBI-1052479|uniprotkb:Q2M2I2|uniprotkb:B2R751|ensembl:ENSP00000244534 psi-mi:jmjd6_human(display_long)|uniprotkb:PTDSR(gene name synonym)|uniprotkb:KIAA0585(gene name synonym)|uniprotkb:JMJD6(gene name)|psi-mi:JMJD6(display_short)|uniprotkb:Histone arginine demethylase JMJD6(gene name synonym)|uniprotkb:JmjC domain-containing protein 6(gene name synonym)|uniprotkb:Jumonji domain-containing protein 6(gene name synonym)|uniprotkb:Lysyl-hydroxylase JMJD6(gene name synonym)|uniprotkb:Peptide-lysine 5-dioxygenase JMJD6(gene name synonym)|uniprotkb:Phosphatidylserine receptor(gene name synonym)|uniprotkb:PSR(gene name synonym) psi-mi:h13_human(display_long)|uniprotkb:H1-3(gene name)|psi-mi:H1-3(display_short)|uniprotkb:H1F3(gene name synonym)|uniprotkb:HIST1H1D(gene name synonym)|uniprotkb:Histone H1c(gene name synonym)|uniprotkb:Histone H1s-2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479708|imex:IM-26985-329 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055982.2|refseq:NP_001074930.1|dip:DIP-60686N|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006482"(protein demethylation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0008380"(RNA splicing)|go:"GO:0018395"(peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine)|go:"GO:0005506"(iron ion binding)|go:"GO:0030324"(lung development)|go:"GO:0032451"(demethylase activity)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033746"(histone H3-methyl-arginine-2 demethylase activity)|go:"GO:0033749"(histone H3-methyl-arginine-3 demethylase activity)|go:"GO:0035513"(oxidative RNA demethylation)|go:"GO:0035515"(oxidative RNA demethylase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042116"(macrophage activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048821"(erythrocyte development)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070078"(histone H3-R2 demethylation)|go:"GO:0070079"(histone H4-R3 demethylation)|go:"GO:0070815"(peptidyl-lysine 5-dioxygenase activity)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0140537"(transcription regulator activator activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q6NYC1|rcsb pdb:3K2O|rcsb pdb:3LD8|rcsb pdb:3LDB|rcsb pdb:6BNH|go:"GO:0043654"(recognition of apoptotic cell)|rcsb pdb:6MEV|reactome:R-HSA-3214842|rcsb pdb:6GDY|ensembl:ENSG00000070495(gene)|ensembl:ENST00000397625(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding) refseq:NP_005311.1|ensembl:ENSG00000124575(gene)|ensembl:ENST00000244534(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P16402|reactome:R-HSA-140342|reactome:R-HSA-2559584 - comment:mint|comment:homomint|function:Arginine demethylase which demethylates histone H3 at 'Arg-3' and histone H4 at 'Arg-4'. Required for differentiation of multiple organs during embryogenesis. Probably acts as a key regulator of hematopoietic differentiation. Seems to be necessary for the regulation of macrophage cytokine responses comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:YbwfNgf/c4ug+02lkCn2C4tMLEI9606 rogid:EKx3L/uC7g4QkB/3ARuTL97tMbw9606 rigid:o3vXtnaFZ1GZUPqWYoaOaIPmqDA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6NYC1 uniprotkb:O43324 intact:EBI-8464037|uniprotkb:Q9Y4E2|uniprotkb:B4DGX1|uniprotkb:Q8IUM5|uniprotkb:B3KMN8|intact:MINT-3086431|uniprotkb:Q86VY0|ensembl:ENSP00000380750 intact:EBI-1048486|uniprotkb:Q5THS2|ensembl:ENSP00000369038|uniprotkb:C9JLK5 psi-mi:jmjd6_human(display_long)|uniprotkb:PTDSR(gene name synonym)|uniprotkb:KIAA0585(gene name synonym)|uniprotkb:JMJD6(gene name)|psi-mi:JMJD6(display_short)|uniprotkb:Histone arginine demethylase JMJD6(gene name synonym)|uniprotkb:JmjC domain-containing protein 6(gene name synonym)|uniprotkb:Jumonji domain-containing protein 6(gene name synonym)|uniprotkb:Lysyl-hydroxylase JMJD6(gene name synonym)|uniprotkb:Peptide-lysine 5-dioxygenase JMJD6(gene name synonym)|uniprotkb:Phosphatidylserine receptor(gene name synonym)|uniprotkb:PSR(gene name synonym) psi-mi:mca3_human(display_long)|uniprotkb:Multisynthase complex auxiliary component p18(gene name synonym)|uniprotkb:Elongation factor p18(gene name synonym)|uniprotkb:EEF1E1(gene name)|psi-mi:EEF1E1(display_short)|uniprotkb:P18(gene name synonym)|uniprotkb:AIMP3(gene name synonym)|uniprotkb:Aminoacyl tRNA synthetase complex-interacting multifunctional protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479708|imex:IM-26985-329 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055982.2|refseq:NP_001074930.1|dip:DIP-60686N|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006482"(protein demethylation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0008380"(RNA splicing)|go:"GO:0018395"(peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine)|go:"GO:0005506"(iron ion binding)|go:"GO:0030324"(lung development)|go:"GO:0032451"(demethylase activity)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033746"(histone H3-methyl-arginine-2 demethylase activity)|go:"GO:0033749"(histone H3-methyl-arginine-3 demethylase activity)|go:"GO:0035513"(oxidative RNA demethylation)|go:"GO:0035515"(oxidative RNA demethylase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042116"(macrophage activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048821"(erythrocyte development)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070078"(histone H3-R2 demethylation)|go:"GO:0070079"(histone H4-R3 demethylation)|go:"GO:0070815"(peptidyl-lysine 5-dioxygenase activity)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0140537"(transcription regulator activator activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q6NYC1|rcsb pdb:3K2O|rcsb pdb:3LD8|rcsb pdb:3LDB|rcsb pdb:6BNH|go:"GO:0043654"(recognition of apoptotic cell)|rcsb pdb:6MEV|reactome:R-HSA-3214842|rcsb pdb:6GDY|ensembl:ENSG00000070495(gene)|ensembl:ENST00000397625(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding) refseq:NP_001129122.1|refseq:NP_004271.1|ensembl:ENSG00000124802(gene)|ensembl:ENST00000379715(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036282|interpro:IPR042450|mint:O43324|rcsb pdb:2UZ8|go:"GO:0043065"(positive regulation of apoptotic process)|rcsb pdb:4BL7|rcsb pdb:4BVX|rcsb pdb:4BVY|rcsb pdb:5BMU|rcsb pdb:5Y6L|reactome:R-HSA-2408522|reactome:R-HSA-379716|dip:DIP-50581N - comment:mint|comment:homomint|function:Arginine demethylase which demethylates histone H3 at 'Arg-3' and histone H4 at 'Arg-4'. Required for differentiation of multiple organs during embryogenesis. Probably acts as a key regulator of hematopoietic differentiation. Seems to be necessary for the regulation of macrophage cytokine responses comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:YbwfNgf/c4ug+02lkCn2C4tMLEI9606 rogid:4AuJouC9q6uAH/4EH8SKSPHyEZU9606 rigid:o3vXtnaFZ1GZUPqWYoaOaIPmqDA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6NYC1 uniprotkb:O75323 intact:EBI-8464037|uniprotkb:Q9Y4E2|uniprotkb:B4DGX1|uniprotkb:Q8IUM5|uniprotkb:B3KMN8|intact:MINT-3086431|uniprotkb:Q86VY0|ensembl:ENSP00000380750 intact:EBI-307133|uniprotkb:O43801|uniprotkb:Q53X96|uniprotkb:C9IYJ3|ensembl:ENSP00000313050 psi-mi:jmjd6_human(display_long)|uniprotkb:PTDSR(gene name synonym)|uniprotkb:KIAA0585(gene name synonym)|uniprotkb:JMJD6(gene name)|psi-mi:JMJD6(display_short)|uniprotkb:Histone arginine demethylase JMJD6(gene name synonym)|uniprotkb:JmjC domain-containing protein 6(gene name synonym)|uniprotkb:Jumonji domain-containing protein 6(gene name synonym)|uniprotkb:Lysyl-hydroxylase JMJD6(gene name synonym)|uniprotkb:Peptide-lysine 5-dioxygenase JMJD6(gene name synonym)|uniprotkb:Phosphatidylserine receptor(gene name synonym)|uniprotkb:PSR(gene name synonym) psi-mi:nips2_human(display_long)|uniprotkb:NIPSNAP2(gene name)|psi-mi:NIPSNAP2(display_short)|uniprotkb:GBAS(gene name synonym)|uniprotkb:Glioblastoma-amplified sequence(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479708|imex:IM-26985-329 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055982.2|refseq:NP_001074930.1|dip:DIP-60686N|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006482"(protein demethylation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0008380"(RNA splicing)|go:"GO:0018395"(peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine)|go:"GO:0005506"(iron ion binding)|go:"GO:0030324"(lung development)|go:"GO:0032451"(demethylase activity)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033746"(histone H3-methyl-arginine-2 demethylase activity)|go:"GO:0033749"(histone H3-methyl-arginine-3 demethylase activity)|go:"GO:0035513"(oxidative RNA demethylation)|go:"GO:0035515"(oxidative RNA demethylase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042116"(macrophage activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048821"(erythrocyte development)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070078"(histone H3-R2 demethylation)|go:"GO:0070079"(histone H4-R3 demethylation)|go:"GO:0070815"(peptidyl-lysine 5-dioxygenase activity)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0140537"(transcription regulator activator activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q6NYC1|rcsb pdb:3K2O|rcsb pdb:3LD8|rcsb pdb:3LDB|rcsb pdb:6BNH|go:"GO:0043654"(recognition of apoptotic cell)|rcsb pdb:6MEV|reactome:R-HSA-3214842|rcsb pdb:6GDY|ensembl:ENSG00000070495(gene)|ensembl:ENST00000397625(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding) refseq:NP_001189398.1|refseq:NP_001474.1|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0007005"(mitochondrion organization)|go:"GO:1901843"(positive regulation of high voltage-gated calcium channel activity)|interpro:IPR011008(Dimeric alpha-beta barrel)|interpro:IPR012577(NIPSNAP)|mint:O75323|reactome:R-HSA-9013407|reactome:R-HSA-9013409|ensembl:ENSG00000146729(gene)|ensembl:ENST00000322090(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|dip:DIP-33564N - comment:mint|comment:homomint|function:Arginine demethylase which demethylates histone H3 at 'Arg-3' and histone H4 at 'Arg-4'. Required for differentiation of multiple organs during embryogenesis. Probably acts as a key regulator of hematopoietic differentiation. Seems to be necessary for the regulation of macrophage cytokine responses comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:YbwfNgf/c4ug+02lkCn2C4tMLEI9606 rogid:sfBQGdtSVoH21kBu/Bz9x8x3KWU9606 rigid:o3vXtnaFZ1GZUPqWYoaOaIPmqDA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6NYC1 uniprotkb:P30042 intact:EBI-8464037|uniprotkb:Q9Y4E2|uniprotkb:B4DGX1|uniprotkb:Q8IUM5|uniprotkb:B3KMN8|intact:MINT-3086431|uniprotkb:Q86VY0|ensembl:ENSP00000380750 intact:EBI-723904|uniprotkb:A6NFJ6|uniprotkb:A6NJY7|uniprotkb:O00650|uniprotkb:O00660|uniprotkb:O15011|uniprotkb:O15012|uniprotkb:P55346|uniprotkb:P78474|uniprotkb:Q92505|uniprotkb:Q92507|uniprotkb:P0DPI2 psi-mi:jmjd6_human(display_long)|uniprotkb:PTDSR(gene name synonym)|uniprotkb:KIAA0585(gene name synonym)|uniprotkb:JMJD6(gene name)|psi-mi:JMJD6(display_short)|uniprotkb:Histone arginine demethylase JMJD6(gene name synonym)|uniprotkb:JmjC domain-containing protein 6(gene name synonym)|uniprotkb:Jumonji domain-containing protein 6(gene name synonym)|uniprotkb:Lysyl-hydroxylase JMJD6(gene name synonym)|uniprotkb:Peptide-lysine 5-dioxygenase JMJD6(gene name synonym)|uniprotkb:Phosphatidylserine receptor(gene name synonym)|uniprotkb:PSR(gene name synonym) psi-mi:es1_human(display_long)|uniprotkb:Protein KNP-I(gene name synonym)|uniprotkb:Protein GT335(gene name synonym)|uniprotkb:C21orf33(gene name)|psi-mi:C21orf33(display_short)|uniprotkb:HES1(gene name synonym)|uniprotkb:KNPI(gene name synonym)|uniprotkb:GATD3A(gene name)|psi-mi:GATD3A(display_short)|uniprotkb:C21orf33(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479708|imex:IM-26985-329 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055982.2|refseq:NP_001074930.1|dip:DIP-60686N|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006482"(protein demethylation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0008380"(RNA splicing)|go:"GO:0018395"(peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine)|go:"GO:0005506"(iron ion binding)|go:"GO:0030324"(lung development)|go:"GO:0032451"(demethylase activity)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033746"(histone H3-methyl-arginine-2 demethylase activity)|go:"GO:0033749"(histone H3-methyl-arginine-3 demethylase activity)|go:"GO:0035513"(oxidative RNA demethylation)|go:"GO:0035515"(oxidative RNA demethylase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042116"(macrophage activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048821"(erythrocyte development)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070078"(histone H3-R2 demethylation)|go:"GO:0070079"(histone H4-R3 demethylation)|go:"GO:0070815"(peptidyl-lysine 5-dioxygenase activity)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0140537"(transcription regulator activator activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q6NYC1|rcsb pdb:3K2O|rcsb pdb:3LD8|rcsb pdb:3LDB|rcsb pdb:6BNH|go:"GO:0043654"(recognition of apoptotic cell)|rcsb pdb:6MEV|reactome:R-HSA-3214842|rcsb pdb:6GDY|ensembl:ENSG00000070495(gene)|ensembl:ENST00000397625(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding) go:"GO:0005739"(mitochondrion)|refseq:NP_004640.4|refseq:NP_937798.4|refseq:XP_011507206.1|refseq:XP_011507208.1|interpro:IPR029062|ensembl:ENST00000291577|ensembl:ENST00000348499|refseq:XP_006723964.1|refseq:XP_006723966.1|ensembl:ENSG00000160221|ensembl:ENSP00000291577|ensembl:ENSP00000344901 - comment:mint|comment:homomint|function:Arginine demethylase which demethylates histone H3 at 'Arg-3' and histone H4 at 'Arg-4'. Required for differentiation of multiple organs during embryogenesis. Probably acts as a key regulator of hematopoietic differentiation. Seems to be necessary for the regulation of macrophage cytokine responses comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:YbwfNgf/c4ug+02lkCn2C4tMLEI9606 rogid:CV66j34bvaZ1sxNMzdW2acrkgZA9606 rigid:o3vXtnaFZ1GZUPqWYoaOaIPmqDA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6NYC1 uniprotkb:Q15019 intact:EBI-8464037|uniprotkb:Q9Y4E2|uniprotkb:B4DGX1|uniprotkb:Q8IUM5|uniprotkb:B3KMN8|intact:MINT-3086431|uniprotkb:Q86VY0|ensembl:ENSP00000380750 intact:EBI-741220|intact:EBI-28986019|ensembl:ENSP00000353157|ensembl:ENSP00000375832|ensembl:ENSP00000375834|ensembl:ENSP00000385172|uniprotkb:Q14132|uniprotkb:Q8IUK9|uniprotkb:Q96CB0|uniprotkb:B4DGE8|uniprotkb:Q53QU3 psi-mi:jmjd6_human(display_long)|uniprotkb:PTDSR(gene name synonym)|uniprotkb:KIAA0585(gene name synonym)|uniprotkb:JMJD6(gene name)|psi-mi:JMJD6(display_short)|uniprotkb:Histone arginine demethylase JMJD6(gene name synonym)|uniprotkb:JmjC domain-containing protein 6(gene name synonym)|uniprotkb:Jumonji domain-containing protein 6(gene name synonym)|uniprotkb:Lysyl-hydroxylase JMJD6(gene name synonym)|uniprotkb:Peptide-lysine 5-dioxygenase JMJD6(gene name synonym)|uniprotkb:Phosphatidylserine receptor(gene name synonym)|uniprotkb:PSR(gene name synonym) psi-mi:sept2_human(display_long)|uniprotkb:SEPTIN2(gene name)|psi-mi:SEPTIN2(display_short)|uniprotkb:DIFF6(gene name synonym)|uniprotkb:KIAA0158(gene name synonym)|uniprotkb:NEDD5(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 5(gene name synonym)|uniprotkb:SEPT2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479708|imex:IM-26985-329 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055982.2|refseq:NP_001074930.1|dip:DIP-60686N|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006482"(protein demethylation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0008380"(RNA splicing)|go:"GO:0018395"(peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine)|go:"GO:0005506"(iron ion binding)|go:"GO:0030324"(lung development)|go:"GO:0032451"(demethylase activity)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033746"(histone H3-methyl-arginine-2 demethylase activity)|go:"GO:0033749"(histone H3-methyl-arginine-3 demethylase activity)|go:"GO:0035513"(oxidative RNA demethylation)|go:"GO:0035515"(oxidative RNA demethylase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042116"(macrophage activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048821"(erythrocyte development)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070078"(histone H3-R2 demethylation)|go:"GO:0070079"(histone H4-R3 demethylation)|go:"GO:0070815"(peptidyl-lysine 5-dioxygenase activity)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0140537"(transcription regulator activator activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q6NYC1|rcsb pdb:3K2O|rcsb pdb:3LD8|rcsb pdb:3LDB|rcsb pdb:6BNH|go:"GO:0043654"(recognition of apoptotic cell)|rcsb pdb:6MEV|reactome:R-HSA-3214842|rcsb pdb:6GDY|ensembl:ENSG00000070495(gene)|ensembl:ENST00000397625(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding) refseq:NP_001269901.1|refseq:NP_001269902.1|ensembl:ENSG00000168385(gene)|ensembl:ENST00000360051(transcript)|ensembl:ENST00000391971(transcript)|ensembl:ENST00000391973(transcript)|ensembl:ENST00000402092(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|interpro:IPR008113(Septin 2)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|mint:Q15019|rcsb pdb:2QA5|rcsb pdb:2QAG|rcsb pdb:2QNR|rcsb pdb:6UPA|rcsb pdb:6UPQ|rcsb pdb:6UPR|reactome:R-HSA-5620912|refseq:NP_001008491.1|refseq:NP_001008492.1|refseq:NP_004395.1|refseq:NP_006146.1|refseq:XP_016859694.1|refseq:XP_016859695.1|refseq:NP_001307958.1|refseq:NP_001307959.1|refseq:NP_001307960.1|refseq:NP_001307961.1|refseq:NP_001307962.1|refseq:NP_001307963.1|refseq:NP_001307964.1|ensembl:ENSP00000353157|ensembl:ENSP00000375832|ensembl:ENSP00000375834|ensembl:ENST00000401990|ensembl:ENSP00000385109|ensembl:ENSP00000385172|ensembl:ENST00000616972|ensembl:ENSP00000479861|dip:DIP-38220N - comment:mint|comment:homomint|function:Arginine demethylase which demethylates histone H3 at 'Arg-3' and histone H4 at 'Arg-4'. Required for differentiation of multiple organs during embryogenesis. Probably acts as a key regulator of hematopoietic differentiation. Seems to be necessary for the regulation of macrophage cytokine responses crc64:12CCBBE30806F92F|comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:YbwfNgf/c4ug+02lkCn2C4tMLEI9606 rogid:H0Us8GtPe2XuXlOYXC0DX79kB/49606 rigid:o3vXtnaFZ1GZUPqWYoaOaIPmqDA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6NYC1 uniprotkb:Q9BU76 intact:EBI-8464037|uniprotkb:Q9Y4E2|uniprotkb:B4DGX1|uniprotkb:Q8IUM5|uniprotkb:B3KMN8|intact:MINT-3086431|uniprotkb:Q86VY0|ensembl:ENSP00000380750 intact:EBI-742459|uniprotkb:Q6P5Y0|uniprotkb:Q6ZTZ6|uniprotkb:Q6ZWA6|uniprotkb:Q8IZH3|ensembl:ENSP00000272139 psi-mi:jmjd6_human(display_long)|uniprotkb:PTDSR(gene name synonym)|uniprotkb:KIAA0585(gene name synonym)|uniprotkb:JMJD6(gene name)|psi-mi:JMJD6(display_short)|uniprotkb:Histone arginine demethylase JMJD6(gene name synonym)|uniprotkb:JmjC domain-containing protein 6(gene name synonym)|uniprotkb:Jumonji domain-containing protein 6(gene name synonym)|uniprotkb:Lysyl-hydroxylase JMJD6(gene name synonym)|uniprotkb:Peptide-lysine 5-dioxygenase JMJD6(gene name synonym)|uniprotkb:Phosphatidylserine receptor(gene name synonym)|uniprotkb:PSR(gene name synonym) psi-mi:mmta2_human(display_long)|uniprotkb:MMTAG2(gene name)|psi-mi:MMTAG2(display_short)|uniprotkb:C1orf35(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479708|imex:IM-26985-329 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055982.2|refseq:NP_001074930.1|dip:DIP-60686N|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006482"(protein demethylation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0008380"(RNA splicing)|go:"GO:0018395"(peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine)|go:"GO:0005506"(iron ion binding)|go:"GO:0030324"(lung development)|go:"GO:0032451"(demethylase activity)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033746"(histone H3-methyl-arginine-2 demethylase activity)|go:"GO:0033749"(histone H3-methyl-arginine-3 demethylase activity)|go:"GO:0035513"(oxidative RNA demethylation)|go:"GO:0035515"(oxidative RNA demethylase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042116"(macrophage activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048821"(erythrocyte development)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070078"(histone H3-R2 demethylation)|go:"GO:0070079"(histone H4-R3 demethylation)|go:"GO:0070815"(peptidyl-lysine 5-dioxygenase activity)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0140537"(transcription regulator activator activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q6NYC1|rcsb pdb:3K2O|rcsb pdb:3LD8|rcsb pdb:3LDB|rcsb pdb:6BNH|go:"GO:0043654"(recognition of apoptotic cell)|rcsb pdb:6MEV|reactome:R-HSA-3214842|rcsb pdb:6GDY|ensembl:ENSG00000070495(gene)|ensembl:ENST00000397625(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding) refseq:NP_077295.1|mint:Q9BU76|reactome:R-HSA-6798695|ensembl:ENSG00000143793(gene)|ensembl:ENST00000272139(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0034774"(secretory granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR019315|interpro:IPR039207 - comment:mint|comment:homomint|function:Arginine demethylase which demethylates histone H3 at 'Arg-3' and histone H4 at 'Arg-4'. Required for differentiation of multiple organs during embryogenesis. Probably acts as a key regulator of hematopoietic differentiation. Seems to be necessary for the regulation of macrophage cytokine responses comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:YbwfNgf/c4ug+02lkCn2C4tMLEI9606 rogid:TwnLhBYwwR6yPCw3sd7g/sPHJd09606 rigid:o3vXtnaFZ1GZUPqWYoaOaIPmqDA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6NYC1 uniprotkb:Q16718 intact:EBI-8464037|uniprotkb:Q9Y4E2|uniprotkb:B4DGX1|uniprotkb:Q8IUM5|uniprotkb:B3KMN8|intact:MINT-3086431|uniprotkb:Q86VY0|ensembl:ENSP00000380750 intact:EBI-746417|uniprotkb:Q6IRX7|uniprotkb:Q5H9R2|uniprotkb:B2RD98|ensembl:ENSP00000347988 psi-mi:jmjd6_human(display_long)|uniprotkb:PTDSR(gene name synonym)|uniprotkb:KIAA0585(gene name synonym)|uniprotkb:JMJD6(gene name)|psi-mi:JMJD6(display_short)|uniprotkb:Histone arginine demethylase JMJD6(gene name synonym)|uniprotkb:JmjC domain-containing protein 6(gene name synonym)|uniprotkb:Jumonji domain-containing protein 6(gene name synonym)|uniprotkb:Lysyl-hydroxylase JMJD6(gene name synonym)|uniprotkb:Peptide-lysine 5-dioxygenase JMJD6(gene name synonym)|uniprotkb:Phosphatidylserine receptor(gene name synonym)|uniprotkb:PSR(gene name synonym) psi-mi:ndua5_human(display_long)|uniprotkb:Complex I subunit B13(gene name synonym)|uniprotkb:NADH-ubiquinone oxidoreductase 13 kDa-B subunit(gene name synonym)|uniprotkb:Complex I-13kD-B(gene name synonym)|uniprotkb:NDUFA5(gene name)|psi-mi:NDUFA5(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479708|imex:IM-26985-329 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055982.2|refseq:NP_001074930.1|dip:DIP-60686N|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006482"(protein demethylation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0008380"(RNA splicing)|go:"GO:0018395"(peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine)|go:"GO:0005506"(iron ion binding)|go:"GO:0030324"(lung development)|go:"GO:0032451"(demethylase activity)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033746"(histone H3-methyl-arginine-2 demethylase activity)|go:"GO:0033749"(histone H3-methyl-arginine-3 demethylase activity)|go:"GO:0035513"(oxidative RNA demethylation)|go:"GO:0035515"(oxidative RNA demethylase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042116"(macrophage activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048821"(erythrocyte development)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070078"(histone H3-R2 demethylation)|go:"GO:0070079"(histone H4-R3 demethylation)|go:"GO:0070815"(peptidyl-lysine 5-dioxygenase activity)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0140537"(transcription regulator activator activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q6NYC1|rcsb pdb:3K2O|rcsb pdb:3LD8|rcsb pdb:3LDB|rcsb pdb:6BNH|go:"GO:0043654"(recognition of apoptotic cell)|rcsb pdb:6MEV|reactome:R-HSA-3214842|rcsb pdb:6GDY|ensembl:ENSG00000070495(gene)|ensembl:ENST00000397625(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding) refseq:NP_004991.1|refseq:NP_001269348.1|refseq:NP_001269350.1|refseq:NP_001269351.1|ensembl:ENSG00000128609(gene)|ensembl:ENST00000355749(transcript)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0032981"(mitochondrial respiratory chain complex I assembly)|interpro:IPR006806(ETC complex I subunit)|mint:Q16718|rcsb pdb:5XTB|rcsb pdb:5XTD|rcsb pdb:5XTH|rcsb pdb:5XTI|reactome:R-HSA-611105|reactome:R-HSA-6799198|reactome:R-HSA-9013408|refseq:NP_001269349.1 - comment:mint|comment:homomint|function:Arginine demethylase which demethylates histone H3 at 'Arg-3' and histone H4 at 'Arg-4'. Required for differentiation of multiple organs during embryogenesis. Probably acts as a key regulator of hematopoietic differentiation. Seems to be necessary for the regulation of macrophage cytokine responses comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:YbwfNgf/c4ug+02lkCn2C4tMLEI9606 rogid:t042+V0dLA6z/X1MQdgkt7ya7qs9606 rigid:o3vXtnaFZ1GZUPqWYoaOaIPmqDA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6NYC1 uniprotkb:P49458 intact:EBI-8464037|uniprotkb:Q9Y4E2|uniprotkb:B4DGX1|uniprotkb:Q8IUM5|uniprotkb:B3KMN8|intact:MINT-3086431|uniprotkb:Q86VY0|ensembl:ENSP00000380750 intact:EBI-350743|uniprotkb:Q6NVX0|uniprotkb:Q8WTW0|ensembl:ENSP00000305230|uniprotkb:A8K0N0 psi-mi:jmjd6_human(display_long)|uniprotkb:PTDSR(gene name synonym)|uniprotkb:KIAA0585(gene name synonym)|uniprotkb:JMJD6(gene name)|psi-mi:JMJD6(display_short)|uniprotkb:Histone arginine demethylase JMJD6(gene name synonym)|uniprotkb:JmjC domain-containing protein 6(gene name synonym)|uniprotkb:Jumonji domain-containing protein 6(gene name synonym)|uniprotkb:Lysyl-hydroxylase JMJD6(gene name synonym)|uniprotkb:Peptide-lysine 5-dioxygenase JMJD6(gene name synonym)|uniprotkb:Phosphatidylserine receptor(gene name synonym)|uniprotkb:PSR(gene name synonym) psi-mi:srp09_human(display_long)|uniprotkb:SRP9(gene name)|psi-mi:SRP9(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479708|imex:IM-26985-329 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055982.2|refseq:NP_001074930.1|dip:DIP-60686N|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006482"(protein demethylation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0008380"(RNA splicing)|go:"GO:0018395"(peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine)|go:"GO:0005506"(iron ion binding)|go:"GO:0030324"(lung development)|go:"GO:0032451"(demethylase activity)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033746"(histone H3-methyl-arginine-2 demethylase activity)|go:"GO:0033749"(histone H3-methyl-arginine-3 demethylase activity)|go:"GO:0035513"(oxidative RNA demethylation)|go:"GO:0035515"(oxidative RNA demethylase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042116"(macrophage activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048821"(erythrocyte development)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070078"(histone H3-R2 demethylation)|go:"GO:0070079"(histone H4-R3 demethylation)|go:"GO:0070815"(peptidyl-lysine 5-dioxygenase activity)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0140537"(transcription regulator activator activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q6NYC1|rcsb pdb:3K2O|rcsb pdb:3LD8|rcsb pdb:3LDB|rcsb pdb:6BNH|go:"GO:0043654"(recognition of apoptotic cell)|rcsb pdb:6MEV|reactome:R-HSA-3214842|rcsb pdb:6GDY|ensembl:ENSG00000070495(gene)|ensembl:ENST00000397625(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding) rcsb pdb:4UYJ|refseq:NP_001123912.1|refseq:NP_003124.1|ensembl:ENSG00000143742(gene)|ensembl:ENST00000304786(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005047"(signal recognition particle binding)|go:"GO:0005785"(signal recognition particle receptor complex)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|go:"GO:0045900"(negative regulation of translational elongation)|interpro:IPR008832(Signal recognition particle, SRP9 subunit)|interpro:IPR009018(Signal recognition particle, SRP9/SRP14 subunit)|interpro:IPR039432|interpro:IPR039914|mint:P49458|rcsb pdb:1E8O|rcsb pdb:1E8S|rcsb pdb:1RY1|rcsb pdb:4UYK|rcsb pdb:5AOX|rcsb pdb:7NFX|reactome:R-HSA-1799339|dip:DIP-6151N - comment:mint|comment:homomint|function:Arginine demethylase which demethylates histone H3 at 'Arg-3' and histone H4 at 'Arg-4'. Required for differentiation of multiple organs during embryogenesis. Probably acts as a key regulator of hematopoietic differentiation. Seems to be necessary for the regulation of macrophage cytokine responses comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:YbwfNgf/c4ug+02lkCn2C4tMLEI9606 rogid:Y33fEeeXnma9oF7Fzs6zEGQjVBU9606 rigid:o3vXtnaFZ1GZUPqWYoaOaIPmqDA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6NYC1 uniprotkb:Q8N5F7 intact:EBI-8464037|uniprotkb:Q9Y4E2|uniprotkb:B4DGX1|uniprotkb:Q8IUM5|uniprotkb:B3KMN8|intact:MINT-3086431|uniprotkb:Q86VY0|ensembl:ENSP00000380750 intact:EBI-721539|uniprotkb:Q96BQ2|uniprotkb:Q9H638|intact:EBI-745962|intact:EBI-1055594|uniprotkb:Q6IPW6|ensembl:ENSP00000360464 psi-mi:jmjd6_human(display_long)|uniprotkb:PTDSR(gene name synonym)|uniprotkb:KIAA0585(gene name synonym)|uniprotkb:JMJD6(gene name)|psi-mi:JMJD6(display_short)|uniprotkb:Histone arginine demethylase JMJD6(gene name synonym)|uniprotkb:JmjC domain-containing protein 6(gene name synonym)|uniprotkb:Jumonji domain-containing protein 6(gene name synonym)|uniprotkb:Lysyl-hydroxylase JMJD6(gene name synonym)|uniprotkb:Peptide-lysine 5-dioxygenase JMJD6(gene name synonym)|uniprotkb:Phosphatidylserine receptor(gene name synonym)|uniprotkb:PSR(gene name synonym) psi-mi:nkap_human(display_long)|uniprotkb:NKAP(gene name)|psi-mi:NKAP(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479708|imex:IM-26985-329 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055982.2|refseq:NP_001074930.1|dip:DIP-60686N|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006482"(protein demethylation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0008380"(RNA splicing)|go:"GO:0018395"(peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine)|go:"GO:0005506"(iron ion binding)|go:"GO:0030324"(lung development)|go:"GO:0032451"(demethylase activity)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033746"(histone H3-methyl-arginine-2 demethylase activity)|go:"GO:0033749"(histone H3-methyl-arginine-3 demethylase activity)|go:"GO:0035513"(oxidative RNA demethylation)|go:"GO:0035515"(oxidative RNA demethylase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042116"(macrophage activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048821"(erythrocyte development)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070078"(histone H3-R2 demethylation)|go:"GO:0070079"(histone H4-R3 demethylation)|go:"GO:0070815"(peptidyl-lysine 5-dioxygenase activity)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0140537"(transcription regulator activator activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q6NYC1|rcsb pdb:3K2O|rcsb pdb:3LD8|rcsb pdb:3LDB|rcsb pdb:6BNH|go:"GO:0043654"(recognition of apoptotic cell)|rcsb pdb:6MEV|reactome:R-HSA-3214842|rcsb pdb:6GDY|ensembl:ENSG00000070495(gene)|ensembl:ENST00000397625(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding) refseq:NP_078804.2|ensembl:ENSG00000101882(gene)|ensembl:ENST00000371410(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046638"(positive regulation of alpha-beta T cell differentiation)|interpro:IPR009269(Protein of unknown function DUF926)|interpro:IPR040466|mint:Q8N5F7|rcsb pdb:6QDV - comment:mint|comment:homomint|function:Arginine demethylase which demethylates histone H3 at 'Arg-3' and histone H4 at 'Arg-4'. Required for differentiation of multiple organs during embryogenesis. Probably acts as a key regulator of hematopoietic differentiation. Seems to be necessary for the regulation of macrophage cytokine responses comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:YbwfNgf/c4ug+02lkCn2C4tMLEI9606 rogid:AiSgP+Qr12IZX1LBTsna82wmkks9606 rigid:o3vXtnaFZ1GZUPqWYoaOaIPmqDA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6NYC1 uniprotkb:Q9UJV9 intact:EBI-8464037|uniprotkb:Q9Y4E2|uniprotkb:B4DGX1|uniprotkb:Q8IUM5|uniprotkb:B3KMN8|intact:MINT-3086431|uniprotkb:Q86VY0|ensembl:ENSP00000380750 intact:EBI-1046350|ensembl:ENSP00000330349|uniprotkb:Q96BK6|uniprotkb:Q96K05|uniprotkb:Q9NT96|uniprotkb:Q9NW04|uniprotkb:B2RDC8 psi-mi:jmjd6_human(display_long)|uniprotkb:PTDSR(gene name synonym)|uniprotkb:KIAA0585(gene name synonym)|uniprotkb:JMJD6(gene name)|psi-mi:JMJD6(display_short)|uniprotkb:Histone arginine demethylase JMJD6(gene name synonym)|uniprotkb:JmjC domain-containing protein 6(gene name synonym)|uniprotkb:Jumonji domain-containing protein 6(gene name synonym)|uniprotkb:Lysyl-hydroxylase JMJD6(gene name synonym)|uniprotkb:Peptide-lysine 5-dioxygenase JMJD6(gene name synonym)|uniprotkb:Phosphatidylserine receptor(gene name synonym)|uniprotkb:PSR(gene name synonym) psi-mi:ddx41_human(display_long)|uniprotkb:DEAD box protein 41(gene name synonym)|uniprotkb:DEAD box protein abstrakt homolog(gene name synonym)|uniprotkb:DDX41(gene name)|psi-mi:DDX41(display_short)|uniprotkb:ABS(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479708|imex:IM-26985-329 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055982.2|refseq:NP_001074930.1|dip:DIP-60686N|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006482"(protein demethylation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0008380"(RNA splicing)|go:"GO:0018395"(peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine)|go:"GO:0005506"(iron ion binding)|go:"GO:0030324"(lung development)|go:"GO:0032451"(demethylase activity)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033746"(histone H3-methyl-arginine-2 demethylase activity)|go:"GO:0033749"(histone H3-methyl-arginine-3 demethylase activity)|go:"GO:0035513"(oxidative RNA demethylation)|go:"GO:0035515"(oxidative RNA demethylase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042116"(macrophage activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048821"(erythrocyte development)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070078"(histone H3-R2 demethylation)|go:"GO:0070079"(histone H4-R3 demethylation)|go:"GO:0070815"(peptidyl-lysine 5-dioxygenase activity)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0140537"(transcription regulator activator activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q6NYC1|rcsb pdb:3K2O|rcsb pdb:3LD8|rcsb pdb:3LDB|rcsb pdb:6BNH|go:"GO:0043654"(recognition of apoptotic cell)|rcsb pdb:6MEV|reactome:R-HSA-3214842|rcsb pdb:6GDY|ensembl:ENSG00000070495(gene)|ensembl:ENST00000397625(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding) ensembl:ENSG00000183258(gene)|ensembl:ENST00000330503(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR044113|mint:Q9UJV9|rcsb pdb:2P6N|rcsb pdb:5GVS|rcsb pdb:5H1Y|reactome:R-HSA-1834941|reactome:R-HSA-3134975|reactome:R-HSA-3270619|rcsb pdb:5GVR|refseq:NP_057306.2|refseq:NP_001308661.1|refseq:NP_001308759.1 - comment:mint|comment:homomint|function:Arginine demethylase which demethylates histone H3 at 'Arg-3' and histone H4 at 'Arg-4'. Required for differentiation of multiple organs during embryogenesis. Probably acts as a key regulator of hematopoietic differentiation. Seems to be necessary for the regulation of macrophage cytokine responses comment:"author score: 27" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:YbwfNgf/c4ug+02lkCn2C4tMLEI9606 rogid:a3HNDsQBaXs/1q8ZXjkcMgEhPes9606 rigid:o3vXtnaFZ1GZUPqWYoaOaIPmqDA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NX55 uniprotkb:P04908 intact:EBI-1048743|uniprotkb:C9JKJ0|uniprotkb:O75408|uniprotkb:Q8WUW8|uniprotkb:Q9P024|intact:EBI-2561119|ensembl:ENSP00000384474|ensembl:ENSP00000401155 intact:EBI-358971|uniprotkb:Q76P63|uniprotkb:P28001|ensembl:ENSP00000303373|ensembl:ENSP00000483842 psi-mi:hypk_human(display_long)|uniprotkb:Huntingtin yeast partner K(gene name synonym)|uniprotkb:HYPK(gene name)|psi-mi:HYPK(display_short)|uniprotkb:C15orf63(gene name synonym)|uniprotkb:HSPC136(orf name) psi-mi:h2a1b_human(display_long)|uniprotkb:H2AC4(gene name)|psi-mi:H2AC4(display_short)|uniprotkb:H2AC8(gene name)|psi-mi:H2AC8(display_short)|uniprotkb:H2AFA(gene name synonym)|uniprotkb:H2AFM(gene name synonym)|uniprotkb:HIST1H2AB(gene name synonym)|uniprotkb:HIST1H2AE(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/a(gene name synonym)|uniprotkb:Histone H2A/m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479483|imex:IM-26985-327 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186814.1|refseq:NP_057484.3|ensembl:ENSG00000242028(gene)|ensembl:ENST00000406925(transcript)|ensembl:ENST00000442995(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|interpro:IPR038922|interpro:IPR044034|mint:Q9NX55|rcsb pdb:6C95|rcsb pdb:6PW9|go:"GO:0005634"(nucleus) refseq:NP_003504.2|refseq:NP_066390.1|ensembl:ENSG00000277075(gene)|ensembl:ENSG00000278463(gene)|ensembl:ENST00000303910(transcript)|ensembl:ENST00000615868(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P04908|rcsb pdb:2CV5|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1V|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACL|rcsb pdb:6AEE|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6KE9|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V92|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|rcsb pdb:6JXD|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|dip:DIP-44197N - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:wjTSKBV77O3kiF9aRgslJIwvZYI9606 rogid:4Qno1mMYZB6FdNoojrzulWLVq849606 rigid:CBU6EeSzojHSPhV8C9pELAVBDDg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NX55 uniprotkb:P56134 intact:EBI-1048743|uniprotkb:C9JKJ0|uniprotkb:O75408|uniprotkb:Q8WUW8|uniprotkb:Q9P024|intact:EBI-2561119|ensembl:ENSP00000384474|ensembl:ENSP00000401155 intact:EBI-712794|ensembl:ENSP00000292475|uniprotkb:O76079|uniprotkb:Q96L83|uniprotkb:Q9BTI8|uniprotkb:C9J8H9|uniprotkb:F8W7V3|intact:EBI-11047094|uniprotkb:Q6IBB3 psi-mi:hypk_human(display_long)|uniprotkb:Huntingtin yeast partner K(gene name synonym)|uniprotkb:HYPK(gene name)|psi-mi:HYPK(display_short)|uniprotkb:C15orf63(gene name synonym)|uniprotkb:HSPC136(orf name) psi-mi:atpk_human(display_long)|uniprotkb:ATP5MF(gene name)|psi-mi:ATP5MF(display_short)|uniprotkb:ATP synthase membrane subunit f(gene name synonym)|uniprotkb:ATP5J2(gene name synonym)|uniprotkb:ATP5JL(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479483|imex:IM-26985-327 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186814.1|refseq:NP_057484.3|ensembl:ENSG00000242028(gene)|ensembl:ENST00000406925(transcript)|ensembl:ENST00000442995(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|interpro:IPR038922|interpro:IPR044034|mint:Q9NX55|rcsb pdb:6C95|rcsb pdb:6PW9|go:"GO:0005634"(nucleus) ensembl:ENSG00000241468(gene)|ensembl:ENST00000292475(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR019344|mint:P56134|reactome:R-HSA-163210|reactome:R-HSA-8949613|refseq:NP_001003713.1|refseq:NP_004880.1|refseq:NP_001003714.1|refseq:NP_001034267.1 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:wjTSKBV77O3kiF9aRgslJIwvZYI9606 rogid:+WS7rjFef6JE+mlZ4Q8TF2A+G0E9606 rigid:CBU6EeSzojHSPhV8C9pELAVBDDg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NX55 uniprotkb:P60174 intact:EBI-1048743|uniprotkb:C9JKJ0|uniprotkb:O75408|uniprotkb:Q8WUW8|uniprotkb:Q9P024|intact:EBI-2561119|ensembl:ENSP00000384474|ensembl:ENSP00000401155 intact:EBI-717475|uniprotkb:D3DUS9|uniprotkb:P00938|uniprotkb:Q6IS07|uniprotkb:Q8WWD0|uniprotkb:Q96AG5|uniprotkb:Q6FHP9|uniprotkb:B7Z5D8|ensembl:ENSP00000379933 psi-mi:hypk_human(display_long)|uniprotkb:Huntingtin yeast partner K(gene name synonym)|uniprotkb:HYPK(gene name)|psi-mi:HYPK(display_short)|uniprotkb:C15orf63(gene name synonym)|uniprotkb:HSPC136(orf name) psi-mi:tpis_human(display_long)|uniprotkb:Triose-phosphate isomerase(gene name synonym)|uniprotkb:TPI1(gene name)|psi-mi:TPI1(display_short)|uniprotkb:TPI(gene name synonym)|uniprotkb:Methylglyoxal synthase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479483|imex:IM-26985-327 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186814.1|refseq:NP_057484.3|ensembl:ENSG00000242028(gene)|ensembl:ENST00000406925(transcript)|ensembl:ENST00000442995(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|interpro:IPR038922|interpro:IPR044034|mint:Q9NX55|rcsb pdb:6C95|rcsb pdb:6PW9|go:"GO:0005634"(nucleus) refseq:NP_000356.1|refseq:NP_001152759.1|refseq:NP_001244955.1|ensembl:ENSG00000111669(gene)|ensembl:ENST00000396705(transcript)|go:"GO:0004807"(triose-phosphate isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0008929"(methylglyoxal synthase activity)|go:"GO:0019242"(methylglyoxal biosynthetic process)|go:"GO:0019563"(glycerol catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046166"(glyceraldehyde-3-phosphate biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000652(Triosephosphate isomerase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR020861|interpro:IPR022896|interpro:IPR035990|mint:P60174|rcsb pdb:1HTI|rcsb pdb:1KLG|rcsb pdb:1KLU|rcsb pdb:1WYI|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2JK2|rcsb pdb:2VOM|rcsb pdb:4BR1|rcsb pdb:4E41|rcsb pdb:4POC|rcsb pdb:4POD|rcsb pdb:4UNK|rcsb pdb:4UNL|rcsb pdb:4ZVJ|rcsb pdb:6C2G|rcsb pdb:6D43|rcsb pdb:6NLH|rcsb pdb:6UP1|rcsb pdb:6UP5|rcsb pdb:6UP8|rcsb pdb:6UPF|reactome:R-HSA-70171|reactome:R-HSA-70263 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:wjTSKBV77O3kiF9aRgslJIwvZYI9606 rogid:FaLt6wGI1Bz2Z81gX35p7sOiMbE9606 rigid:CBU6EeSzojHSPhV8C9pELAVBDDg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NX55 uniprotkb:P02647 intact:EBI-1048743|uniprotkb:C9JKJ0|uniprotkb:O75408|uniprotkb:Q8WUW8|uniprotkb:Q9P024|intact:EBI-2561119|ensembl:ENSP00000384474|ensembl:ENSP00000401155 intact:EBI-701692|uniprotkb:Q6LDN9|uniprotkb:Q6Q785|uniprotkb:A8K866|uniprotkb:Q9UCS8|uniprotkb:Q9UCT8|ensembl:ENSP00000236850|ensembl:ENSP00000352471|ensembl:ENSP00000364469|ensembl:ENSP00000364472 psi-mi:hypk_human(display_long)|uniprotkb:Huntingtin yeast partner K(gene name synonym)|uniprotkb:HYPK(gene name)|psi-mi:HYPK(display_short)|uniprotkb:C15orf63(gene name synonym)|uniprotkb:HSPC136(orf name) psi-mi:apoa1_human(display_long)|uniprotkb:APOA1(gene name)|psi-mi:APOA1(display_short)|uniprotkb:Apolipoprotein A1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479483|imex:IM-26985-327 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186814.1|refseq:NP_057484.3|ensembl:ENSG00000242028(gene)|ensembl:ENST00000406925(transcript)|ensembl:ENST00000442995(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|interpro:IPR038922|interpro:IPR044034|mint:Q9NX55|rcsb pdb:6C95|rcsb pdb:6PW9|go:"GO:0005634"(nucleus) refseq:NP_000030.1|refseq:NP_001304946.1|refseq:NP_001304947.1|refseq:NP_001304950.1|dip:DIP-29619N|ensembl:ENSG00000118137(gene)|ensembl:ENST00000236850(transcript)|ensembl:ENST00000359492(transcript)|ensembl:ENST00000375320(transcript)|ensembl:ENST00000375323(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002719"(negative regulation of cytokine production involved in immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007584"(response to nutrient)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0009986"(cell surface)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0010903"(negative regulation of very-low-density lipoprotein particle remodeling)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0015485"(cholesterol binding)|go:"GO:0018158"(protein oxidation)|go:"GO:0018206"(peptidyl-methionine modification)|go:"GO:0019899"(enzyme binding)|go:"GO:0019915"(lipid storage)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030300"(regulation of intestinal cholesterol absorption)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0034190"(apolipoprotein receptor binding)|go:"GO:0034191"(apolipoprotein A-I receptor binding)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034363"(intermediate-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034365"(discoidal high-density lipoprotein particle)|go:"GO:0034366"(spherical high-density lipoprotein particle)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034384"(high-density lipoprotein particle clearance)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042158"(lipoprotein biosynthetic process)|go:"GO:0042493"|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043627"(response to estrogen)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050821"(protein stabilization)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0051180"(vitamin transport)|go:"GO:0051345"(positive regulation of hydrolase activity)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0055091"(phospholipid homeostasis)|go:"GO:0055102"(lipase inhibitor activity)|go:"GO:0060192"(negative regulation of lipase activity)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0060354"(negative regulation of cell adhesion molecule production)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070508"(cholesterol import)|go:"GO:0070653"(high-density lipoprotein particle receptor binding)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0072562"(blood microparticle)|go:"GO:0120020"(cholesterol transfer activity)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902995"(positive regulation of phospholipid efflux)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000074(Apolipoprotein A1/A4/E)|mint:P02647|rcsb pdb:1AV1|rcsb pdb:1GW3|rcsb pdb:1GW4|rcsb pdb:1ODP|rcsb pdb:1ODQ|rcsb pdb:1ODR|rcsb pdb:2MSC|rcsb pdb:2MSD|rcsb pdb:2MSE|rcsb pdb:2N5E|rcsb pdb:3K2S|rcsb pdb:3R2P|rcsb pdb:4V6M|rcsb pdb:6CC9|rcsb pdb:6CCH|rcsb pdb:6CCX|rcsb pdb:6CLZ|rcsb pdb:6CM1|rcsb pdb:6PTS|rcsb pdb:6PTW|rcsb pdb:6W4E|rcsb pdb:6W4F|rcsb pdb:7KJR|reactome:R-HSA-114608|reactome:R-HSA-1369062|reactome:R-HSA-1989781|reactome:R-HSA-2168880|reactome:R-HSA-3000471|reactome:R-HSA-3000480|reactome:R-HSA-381426|reactome:R-HSA-5682113|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-8963896|reactome:R-HSA-8963901|reactome:R-HSA-8964011|reactome:R-HSA-8964058|reactome:R-HSA-9707616|reactome:R-HSA-975634|reactome:R-HSA-977225 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:wjTSKBV77O3kiF9aRgslJIwvZYI9606 rogid:yEzPDeU8Uu/43dkLLOBAy6ey1vs9606 rigid:CBU6EeSzojHSPhV8C9pELAVBDDg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NX55 uniprotkb:Q6N069 intact:EBI-1048743|uniprotkb:C9JKJ0|uniprotkb:O75408|uniprotkb:Q8WUW8|uniprotkb:Q9P024|intact:EBI-2561119|ensembl:ENSP00000384474|ensembl:ENSP00000401155 intact:EBI-2561139|ensembl:ENSP00000368716|uniprotkb:Q5VSP9|uniprotkb:Q8N5J3|uniprotkb:Q6P2D5|uniprotkb:Q8N870|uniprotkb:B0QZ59 psi-mi:hypk_human(display_long)|uniprotkb:Huntingtin yeast partner K(gene name synonym)|uniprotkb:HYPK(gene name)|psi-mi:HYPK(display_short)|uniprotkb:C15orf63(gene name synonym)|uniprotkb:HSPC136(orf name) psi-mi:naa16_human(display_long)|uniprotkb:NARG1L(gene name synonym)|uniprotkb:NMDA receptor-regulated 1-like protein(gene name synonym)|uniprotkb:NAT2(gene name synonym)|uniprotkb:NAA16(gene name)|psi-mi:NAA16(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479483|imex:IM-26985-327 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186814.1|refseq:NP_057484.3|ensembl:ENSG00000242028(gene)|ensembl:ENST00000406925(transcript)|ensembl:ENST00000442995(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|interpro:IPR038922|interpro:IPR044034|mint:Q9NX55|rcsb pdb:6C95|rcsb pdb:6PW9|go:"GO:0005634"(nucleus) ensembl:ENSG00000172766(gene)|ensembl:ENST00000379406(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006474"(N-terminal protein amino acid acetylation)|go:"GO:0017196"(N-terminal peptidyl-methionine acetylation)|go:"GO:0031415"(NatA complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|interpro:IPR021183|mint:Q6N069|refseq:NP_001104268.1|refseq:NP_060997.2|refseq:NP_078837.3|refseq:XP_011533530.1 - - comment:"author score: 32" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:wjTSKBV77O3kiF9aRgslJIwvZYI9606 rogid:y23dxDxweBtEeb8mEsJ4bgD6N+Q9606 rigid:CBU6EeSzojHSPhV8C9pELAVBDDg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NX55 uniprotkb:Q9BXJ9 intact:EBI-1048743|uniprotkb:C9JKJ0|uniprotkb:O75408|uniprotkb:Q8WUW8|uniprotkb:Q9P024|intact:EBI-2561119|ensembl:ENSP00000384474|ensembl:ENSP00000401155 intact:EBI-1042540|uniprotkb:Q52LG9|uniprotkb:Q8IWH4|uniprotkb:Q8NEV2|uniprotkb:Q9H8P6|uniprotkb:D3DNY6|ensembl:ENSP00000296543 psi-mi:hypk_human(display_long)|uniprotkb:Huntingtin yeast partner K(gene name synonym)|uniprotkb:HYPK(gene name)|psi-mi:HYPK(display_short)|uniprotkb:C15orf63(gene name synonym)|uniprotkb:HSPC136(orf name) psi-mi:naa15_human(display_long)|uniprotkb:NAA15(gene name)|psi-mi:NAA15(display_short)|uniprotkb:GA19(gene name synonym)|uniprotkb:NATH(gene name synonym)|uniprotkb:TBDN100(gene name synonym)|uniprotkb:Gastric cancer antigen Ga19(gene name synonym)|uniprotkb:N-terminal acetyltransferase(gene name synonym)|uniprotkb:Protein tubedown-1(gene name synonym)|uniprotkb:Tbdn100(gene name synonym)|uniprotkb:NARG1(gene name synonym)|uniprotkb:NMDA receptor-regulated protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479483|imex:IM-26985-327 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186814.1|refseq:NP_057484.3|ensembl:ENSG00000242028(gene)|ensembl:ENST00000406925(transcript)|ensembl:ENST00000442995(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|interpro:IPR038922|interpro:IPR044034|mint:Q9NX55|rcsb pdb:6C95|rcsb pdb:6PW9|go:"GO:0005634"(nucleus) refseq:NP_476516.1|go:"GO:0016604"(nuclear body)|go:"GO:0017196"(N-terminal peptidyl-methionine acetylation)|go:"GO:0030154"(cell differentiation)|go:"GO:0031415"(NatA complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0050821"(protein stabilization)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR021183|mint:Q9BXJ9|rcsb pdb:6C95|rcsb pdb:6C9M|rcsb pdb:6PPL|rcsb pdb:6PW9|ensembl:ENSG00000164134(gene)|ensembl:ENST00000296543(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006474"(N-terminal protein amino acid acetylation)|go:"GO:0016020"(membrane) - - comment:"author score: 129" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:wjTSKBV77O3kiF9aRgslJIwvZYI9606 rogid:BGW5jQRBYXuf75thzj6cWvL2A5Y9606 rigid:CBU6EeSzojHSPhV8C9pELAVBDDg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NX55 uniprotkb:P41227 intact:EBI-1048743|uniprotkb:C9JKJ0|uniprotkb:O75408|uniprotkb:Q8WUW8|uniprotkb:Q9P024|intact:EBI-2561119|ensembl:ENSP00000384474|ensembl:ENSP00000401155 intact:EBI-747693|uniprotkb:A6NM98|ensembl:ENSP00000417763 psi-mi:hypk_human(display_long)|uniprotkb:Huntingtin yeast partner K(gene name synonym)|uniprotkb:HYPK(gene name)|psi-mi:HYPK(display_short)|uniprotkb:C15orf63(gene name synonym)|uniprotkb:HSPC136(orf name) psi-mi:naa10_human(display_long)|uniprotkb:ARD1(gene name synonym)|uniprotkb:NAA10(gene name)|psi-mi:NAA10(display_short)|uniprotkb:TE2(gene name synonym)|uniprotkb:NatA catalytic subunit Naa10(gene name synonym)|uniprotkb:ARD1A(gene name synonym)|uniprotkb:N-terminal acetyltransferase complex ARD1 subunit homolog A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479483|imex:IM-26985-327 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001186814.1|refseq:NP_057484.3|ensembl:ENSG00000242028(gene)|ensembl:ENST00000406925(transcript)|ensembl:ENST00000442995(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|interpro:IPR038922|interpro:IPR044034|mint:Q9NX55|rcsb pdb:6C95|rcsb pdb:6PW9|go:"GO:0005634"(nucleus) refseq:NP_001243048.1|refseq:NP_003482.1|ensembl:ENST00000464845(transcript)|go:"GO:0004596"(peptide alpha-N-acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006323"(DNA packaging)|go:"GO:0006473"(protein acetylation)|go:"GO:0006474"(N-terminal protein amino acid acetylation)|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0016020"(membrane)|go:"GO:0017198"(N-terminal peptidyl-serine acetylation)|go:"GO:0018002"(N-terminal peptidyl-glutamic acid acetylation)|go:"GO:0031415"(NatA complex)|go:"GO:1990189"(peptide-serine-N-acetyltransferase activity)|go:"GO:1990190"(peptide-glutamate-N-acetyltransferase activity)|go:"GO:2000719"(negative regulation of maintenance of mitotic sister chromatid cohesion, centromeric)|interpro:IPR000182(GCN5-related N-acetyltransferase)|ensembl:ENSG00000102030(gene)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|mint:P41227|rcsb pdb:6C95|rcsb pdb:6C9M|rcsb pdb:6PPL|rcsb pdb:6PW9 - - comment:"author score: 149" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:wjTSKBV77O3kiF9aRgslJIwvZYI9606 rogid:h9fpQmX5wai9LCuW0bgwlDJQ8R49606 rigid:CBU6EeSzojHSPhV8C9pELAVBDDg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92833 uniprotkb:Q15910 intact:EBI-1222720|uniprotkb:Q5U5L5|uniprotkb:A8K9Z6|uniprotkb:B7Z5S5|uniprotkb:Q86X63|uniprotkb:B7Z8L0|ensembl:ENSP00000341280 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 psi-mi:jard2_human(display_long)|uniprotkb:JARID2(gene name)|psi-mi:JARID2(display_short)|uniprotkb:JMJ(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 2(gene name synonym) psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479615|imex:IM-26985-551 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004964.2|refseq:NP_001253969.1|refseq:XP_005249146.1|refseq:XP_016866323.1|refseq:XP_016866324.1|dip:DIP-45494N|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR036431|mint:Q92833|rcsb pdb:5HYN|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000008083(gene)|ensembl:ENST00000341776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007417"(central nervous system development)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0034721"(histone H3-K4 demethylation, trimethyl-H3-K4-specific)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex") refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:G/oMY7WdV7UyQwfT4MOZyET2fS89606 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 rigid:Q4whHWcCr5+d1UGn+S8a0qnaudA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92833 uniprotkb:O75530 intact:EBI-1222720|uniprotkb:Q5U5L5|uniprotkb:A8K9Z6|uniprotkb:B7Z5S5|uniprotkb:Q86X63|uniprotkb:B7Z8L0|ensembl:ENSP00000341280 intact:EBI-923794|intact:EBI-2839778|intact:EBI-1177693|uniprotkb:A8K7V5|uniprotkb:Q6NTH2|uniprotkb:Q7LDA5|uniprotkb:Q7LDG8|uniprotkb:Q86VV2|uniprotkb:Q9UNY7|uniprotkb:O00149|ensembl:ENSP00000263360|ensembl:ENSP00000500834 psi-mi:jard2_human(display_long)|uniprotkb:JARID2(gene name)|psi-mi:JARID2(display_short)|uniprotkb:JMJ(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 2(gene name synonym) psi-mi:eed_human(display_long)|uniprotkb:EED(gene name)|psi-mi:EED(display_short)|uniprotkb:WD protein associating with integrin cytoplasmic tails 1(gene name synonym)|uniprotkb:Embryonic ectoderm development protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479615|imex:IM-26985-551 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004964.2|refseq:NP_001253969.1|refseq:XP_005249146.1|refseq:XP_016866323.1|refseq:XP_016866324.1|dip:DIP-45494N|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR036431|mint:Q92833|rcsb pdb:5HYN|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000008083(gene)|ensembl:ENST00000341776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007417"(central nervous system development)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0034721"(histone H3-K4 demethylation, trimethyl-H3-K4-specific)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex") refseq:NP_003788.2|refseq:NP_001294936.1|dip:DIP-36673N|ensembl:ENSG00000074266(gene)|ensembl:ENST00000263360(transcript)|ensembl:ENST00000672825(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0021510"(spinal cord development)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:O75530|rcsb pdb:3IIW|rcsb pdb:3IIY|rcsb pdb:3IJ0|rcsb pdb:3IJ1|rcsb pdb:3IJC|rcsb pdb:3JPX|rcsb pdb:3JZG|rcsb pdb:3JZH|rcsb pdb:3JZN|rcsb pdb:3K26|rcsb pdb:3K27|rcsb pdb:4W2R|rcsb pdb:4X3E|rcsb pdb:5GSA|rcsb pdb:5H13|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5K0M|rcsb pdb:5LS6|rcsb pdb:5TTW|rcsb pdb:5U5H|rcsb pdb:5U5K|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5U69|rcsb pdb:5U6D|rcsb pdb:5U8A|rcsb pdb:5U8F|rcsb pdb:5WG6|rcsb pdb:5WP3|rcsb pdb:5WUK|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6SFB|rcsb pdb:6SFC|rcsb pdb:6U4Y|rcsb pdb:6V3X|rcsb pdb:6V3Y|rcsb pdb:6W7F|rcsb pdb:6W7G|rcsb pdb:6WKR|rcsb pdb:6YVI|rcsb pdb:6YVJ|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7KXT|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421 - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:G/oMY7WdV7UyQwfT4MOZyET2fS89606 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA9606 rigid:Q4whHWcCr5+d1UGn+S8a0qnaudA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92833 uniprotkb:Q15022 intact:EBI-1222720|uniprotkb:Q5U5L5|uniprotkb:A8K9Z6|uniprotkb:B7Z5S5|uniprotkb:Q86X63|uniprotkb:B7Z8L0|ensembl:ENSP00000341280 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 psi-mi:jard2_human(display_long)|uniprotkb:JARID2(gene name)|psi-mi:JARID2(display_short)|uniprotkb:JMJ(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 2(gene name synonym) psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479615|imex:IM-26985-551 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004964.2|refseq:NP_001253969.1|refseq:XP_005249146.1|refseq:XP_016866323.1|refseq:XP_016866324.1|dip:DIP-45494N|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR036431|mint:Q92833|rcsb pdb:5HYN|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000008083(gene)|ensembl:ENST00000341776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007417"(central nervous system development)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0034721"(histone H3-K4 demethylation, trimethyl-H3-K4-specific)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex") dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421 - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:G/oMY7WdV7UyQwfT4MOZyET2fS89606 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 rigid:Q4whHWcCr5+d1UGn+S8a0qnaudA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92833 uniprotkb:Q6ZN18 intact:EBI-1222720|uniprotkb:Q5U5L5|uniprotkb:A8K9Z6|uniprotkb:B7Z5S5|uniprotkb:Q86X63|uniprotkb:B7Z8L0|ensembl:ENSP00000341280 intact:EBI-743256|ensembl:ENSP00000381840|uniprotkb:Q59FS5|uniprotkb:Q6ZN62|uniprotkb:Q96BG3 psi-mi:jard2_human(display_long)|uniprotkb:JARID2(gene name)|psi-mi:JARID2(display_short)|uniprotkb:JMJ(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 2(gene name synonym) psi-mi:aebp2_human(display_long)|uniprotkb:Adipocyte enhancer-binding protein 2(gene name synonym)|uniprotkb:AEBP2(gene name)|psi-mi:AEBP2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479615|imex:IM-26985-551 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004964.2|refseq:NP_001253969.1|refseq:XP_005249146.1|refseq:XP_016866323.1|refseq:XP_016866324.1|dip:DIP-45494N|go:"GO:0048536"(spleen development)|go:"GO:0048538"(thymus development)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR036431|mint:Q92833|rcsb pdb:5HYN|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000008083(gene)|ensembl:ENST00000341776(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001889"(liver development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007417"(central nervous system development)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0031061"(negative regulation of histone methylation)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0034721"(histone H3-K4 demethylation, trimethyl-H3-K4-specific)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035098"("ESC/E(Z) complex") ensembl:ENSG00000139154(gene)|interpro:IPR036236|ensembl:ENST00000398864(transcript)|go:"GO:0000785"(chromatin)|mint:Q6ZN18|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001107648.1|refseq:NP_694939.2|rcsb pdb:5WAI|rcsb pdb:5Y0U|rcsb pdb:5Y1U|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|reactome:R-HSA-3214841|refseq:NP_001253972.1|dip:DIP-58581N - - comment:"author score: 33" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:G/oMY7WdV7UyQwfT4MOZyET2fS89606 rogid:mOY+NOTaqJlXjW8v6D3YPnfnfBU9606 rigid:Q4whHWcCr5+d1UGn+S8a0qnaudA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WYH8 uniprotkb:Q6IE81 intact:EBI-488533|uniprotkb:Q9BS30|uniprotkb:A8K1P3|uniprotkb:Q53NU6|uniprotkb:Q57Z54|ensembl:ENSP00000322142 intact:EBI-954672|uniprotkb:Q4W5D5|uniprotkb:Q6ZSL7|uniprotkb:Q8NC41|uniprotkb:Q96JL8|uniprotkb:Q96SQ1|uniprotkb:Q9H692|uniprotkb:D3DNY0|uniprotkb:D3DNY1|ensembl:ENSP00000226319|ensembl:ENSP00000425730|ensembl:ENSP00000482212|ensembl:ENSP00000483219 psi-mi:ing5_human(display_long)|uniprotkb:p28ING5(gene name synonym)|uniprotkb:ING5(gene name)|psi-mi:ING5(display_short) psi-mi:jade1_human(display_long)|uniprotkb:JADE1(gene name)|psi-mi:JADE1(display_short)|uniprotkb:Jade family PHD finger protein 1(gene name synonym)|uniprotkb:KIAA1807(gene name synonym)|uniprotkb:PHD finger protein 17(gene name synonym)|uniprotkb:PHF17(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479561|imex:IM-26985-549 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115705.2|ensembl:ENSG00000168395(gene)|ensembl:ENST00000313552(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006260"(DNA replication)|go:"GO:0006473"(protein acetylation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028638|interpro:IPR028651|mint:Q8WYH8|rcsb pdb:3C6W|rcsb pdb:5ME8|rcsb pdb:5MTO|reactome:R-HSA-3214847|reactome:R-HSA-6804758|refseq:NP_001317091.1|dip:DIP-32511N refseq:NP_079176.2|refseq:NP_955352.1|refseq:NP_001274372.1|refseq:NP_001274366.1|refseq:NP_001274368.1|refseq:NP_001274369.1|refseq:NP_001274370.1|refseq:NP_001274371.1|ensembl:ENSG00000077684(gene)|ensembl:ENST00000226319(transcript)|ensembl:ENST00000512960(transcript)|ensembl:ENST00000610919(transcript)|ensembl:ENST00000611140(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR039546|mint:Q6IE81|reactome:R-HSA-3214847|refseq:XP_005263289.1 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dwJLwzNcL9866noaSFznDKeulRU9606 rogid:brla9icZHYnZBj+2WtExolD2Z489606 rigid:RzUUSQ1owOEVdFCnvd9TBScYx94 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WYH8 uniprotkb:Q6P1K2 intact:EBI-488533|uniprotkb:Q9BS30|uniprotkb:A8K1P3|uniprotkb:Q53NU6|uniprotkb:Q57Z54|ensembl:ENSP00000322142 intact:EBI-713832|uniprotkb:Q5TCJ8|uniprotkb:Q5TCJ9|uniprotkb:Q5TCK3|uniprotkb:Q69YZ9|uniprotkb:Q6PHR4|uniprotkb:Q86VJ6|uniprotkb:Q8N4T6|uniprotkb:Q9UBQ3|uniprotkb:A8K0C5|intact:EBI-2554676|uniprotkb:Q5TCK0|ensembl:ENSP00000357260|uniprotkb:Q5TCK1|uniprotkb:Q6ZVE6 psi-mi:ing5_human(display_long)|uniprotkb:p28ING5(gene name synonym)|uniprotkb:ING5(gene name)|psi-mi:ING5(display_short) psi-mi:pmf1_human(display_long)|uniprotkb:PMF1(gene name)|psi-mi:PMF1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479561|imex:IM-26985-549 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115705.2|ensembl:ENSG00000168395(gene)|ensembl:ENST00000313552(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006260"(DNA replication)|go:"GO:0006473"(protein acetylation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028638|interpro:IPR028651|mint:Q8WYH8|rcsb pdb:3C6W|rcsb pdb:5ME8|rcsb pdb:5MTO|reactome:R-HSA-3214847|reactome:R-HSA-6804758|refseq:NP_001317091.1|dip:DIP-32511N ensembl:ENSG00000160783(gene)|ensembl:ENST00000368277(transcript)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0051301"(cell division)|interpro:IPR007128(Nnf1)|mint:Q6P1K2|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001186582.1|refseq:NP_001186583.1|refseq:NP_001186590.1|refseq:NP_001186592.1|refseq:NP_009152.2 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dwJLwzNcL9866noaSFznDKeulRU9606 rogid:76xPGmFgI3Pt1gsZMb3aD4hpPWM9606 rigid:RzUUSQ1owOEVdFCnvd9TBScYx94 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WYH8 uniprotkb:Q9NQC1 intact:EBI-488533|uniprotkb:Q9BS30|uniprotkb:A8K1P3|uniprotkb:Q53NU6|uniprotkb:Q57Z54|ensembl:ENSP00000322142 intact:EBI-2796167|uniprotkb:D3DQA3|uniprotkb:Q8TEK0|uniprotkb:Q92513|uniprotkb:Q6IE80|uniprotkb:Q96GQ6|ensembl:ENSP00000378451 psi-mi:ing5_human(display_long)|uniprotkb:p28ING5(gene name synonym)|uniprotkb:ING5(gene name)|psi-mi:ING5(display_short) psi-mi:jade2_human(display_long)|uniprotkb:JADE2(gene name)|psi-mi:JADE2(display_short)|uniprotkb:Jade family PHD finger protein 2(gene name synonym)|uniprotkb:KIAA0239(gene name synonym)|uniprotkb:PHD finger protein 15(gene name synonym)|uniprotkb:PHF15(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479561|imex:IM-26985-549 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115705.2|ensembl:ENSG00000168395(gene)|ensembl:ENST00000313552(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006260"(DNA replication)|go:"GO:0006473"(protein acetylation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028638|interpro:IPR028651|mint:Q8WYH8|rcsb pdb:3C6W|rcsb pdb:5ME8|rcsb pdb:5MTO|reactome:R-HSA-3214847|reactome:R-HSA-6804758|refseq:NP_001317091.1|dip:DIP-32511N refseq:NP_056103.4|refseq:NP_001295072.1|refseq:NP_001276913.1|refseq:NP_001276914.1|ensembl:ENSG00000043143(gene)|ensembl:ENST00000395003(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016740"(transferase activity)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR039548|interpro:IPR039549|mint:Q9NQC1|reactome:R-HSA-3214847 - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dwJLwzNcL9866noaSFznDKeulRU9606 rogid:6HE0lz0S6SEAjJGunkR271uFfZQ9606 rigid:RzUUSQ1owOEVdFCnvd9TBScYx94 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WYH8 uniprotkb:Q92613 intact:EBI-488533|uniprotkb:Q9BS30|uniprotkb:A8K1P3|uniprotkb:Q53NU6|uniprotkb:Q57Z54|ensembl:ENSP00000322142 intact:EBI-10278909|uniprotkb:Q6IE79|ensembl:ENSP00000479377|ensembl:ENSP00000481850 psi-mi:ing5_human(display_long)|uniprotkb:p28ING5(gene name synonym)|uniprotkb:ING5(gene name)|psi-mi:ING5(display_short) psi-mi:jade3_human(display_long)|uniprotkb:JADE3(gene name)|psi-mi:JADE3(display_short)|uniprotkb:Jade family PHD finger protein 3(gene name synonym)|uniprotkb:KIAA0215(gene name synonym)|uniprotkb:PHD finger protein 16(gene name synonym)|uniprotkb:PHF16(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479561|imex:IM-26985-549 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115705.2|ensembl:ENSG00000168395(gene)|ensembl:ENST00000313552(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006260"(DNA replication)|go:"GO:0006473"(protein acetylation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028638|interpro:IPR028651|mint:Q8WYH8|rcsb pdb:3C6W|rcsb pdb:5ME8|rcsb pdb:5MTO|reactome:R-HSA-3214847|reactome:R-HSA-6804758|refseq:NP_001317091.1|dip:DIP-32511N refseq:NP_001070913.1|refseq:NP_055550.1|ensembl:ENSG00000102221(gene)|ensembl:ENST00000611250(transcript)|ensembl:ENST00000614628(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR039550|mint:Q92613|reactome:R-HSA-3214847 - - comment:"author score: 27" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dwJLwzNcL9866noaSFznDKeulRU9606 rogid:OUQwlVF1k9d+/zAq0GlCmjOh+8s9606 rigid:RzUUSQ1owOEVdFCnvd9TBScYx94 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WYH8 uniprotkb:Q9ULD4 intact:EBI-488533|uniprotkb:Q9BS30|uniprotkb:A8K1P3|uniprotkb:Q53NU6|uniprotkb:Q57Z54|ensembl:ENSP00000322142 intact:EBI-1753470|uniprotkb:A6NJE2|uniprotkb:Q5R3K8|ensembl:ENSP00000350267|intact:EBI-2860074|uniprotkb:A6ND56|uniprotkb:B7ZLN5|uniprotkb:E7EX85|uniprotkb:Q17RB6 psi-mi:ing5_human(display_long)|uniprotkb:p28ING5(gene name synonym)|uniprotkb:ING5(gene name)|psi-mi:ING5(display_short) psi-mi:brpf3_human(display_long)|uniprotkb:BRPF3(gene name)|psi-mi:BRPF3(display_short)|uniprotkb:KIAA1286(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479561|imex:IM-26985-549 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115705.2|ensembl:ENSG00000168395(gene)|ensembl:ENST00000313552(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006260"(DNA replication)|go:"GO:0006473"(protein acetylation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028638|interpro:IPR028651|mint:Q8WYH8|rcsb pdb:3C6W|rcsb pdb:5ME8|rcsb pdb:5MTO|reactome:R-HSA-3214847|reactome:R-HSA-6804758|refseq:NP_001317091.1|dip:DIP-32511N refseq:XP_011512791.1|refseq:XP_005249067.1|refseq:XP_005249068.1|refseq:NP_056510.2|ensembl:ENSG00000096070(gene)|ensembl:ENST00000357641(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042005|mint:Q9ULD4|rcsb pdb:3PFS|reactome:R-HSA-114608|reactome:R-HSA-3214847|reactome:R-HSA-6804758|interpro:IPR018359 - - comment:"author score: 51" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dwJLwzNcL9866noaSFznDKeulRU9606 rogid:CgyLb1z0upVoKfJxtzvybQ6NAkE9606 rigid:RzUUSQ1owOEVdFCnvd9TBScYx94 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WYH8 uniprotkb:Q92794 intact:EBI-488533|uniprotkb:Q9BS30|uniprotkb:A8K1P3|uniprotkb:Q53NU6|uniprotkb:Q57Z54|ensembl:ENSP00000322142 intact:EBI-948013|intact:EBI-1048839|uniprotkb:Q76L81|ensembl:ENSP00000265713|ensembl:ENSP00000380136 psi-mi:ing5_human(display_long)|uniprotkb:p28ING5(gene name synonym)|uniprotkb:ING5(gene name)|psi-mi:ING5(display_short) psi-mi:kat6a_human(display_long)|uniprotkb:KAT6A(gene name)|psi-mi:KAT6A(display_short)|uniprotkb:MOZ(gene name synonym)|uniprotkb:RUNXBP2(gene name synonym)|uniprotkb:ZNF220(gene name synonym)|uniprotkb:MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3(gene name synonym)|uniprotkb:Runt-related transcription factor-binding protein 2(gene name synonym)|uniprotkb:Monocytic leukemia zinc finger protein(gene name synonym)|uniprotkb:Zinc finger protein 220(gene name synonym)|uniprotkb:MYST3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479561|imex:IM-26985-549 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115705.2|ensembl:ENSG00000168395(gene)|ensembl:ENST00000313552(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006260"(DNA replication)|go:"GO:0006473"(protein acetylation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028638|interpro:IPR028651|mint:Q8WYH8|rcsb pdb:3C6W|rcsb pdb:5ME8|rcsb pdb:5MTO|reactome:R-HSA-3214847|reactome:R-HSA-6804758|refseq:NP_001317091.1|dip:DIP-32511N refseq:NP_006757.2|ensembl:ENSP00000265713|ensembl:ENSP00000380136|refseq:XP_016869352.1|refseq:XP_016869353.1|ensembl:ENSG00000083168(gene)|ensembl:ENST00000265713(transcript)|ensembl:ENST00000396930(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006323"(DNA packaging)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006473"(protein acetylation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|go:"GO:0090398"(cellular senescence)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR005818(Histone H1/H5)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR019787|interpro:IPR031280|interpro:IPR036388|interpro:IPR036390|interpro:IPR040706|mint:Q92794|rcsb pdb:1M36|rcsb pdb:2LN0|rcsb pdb:2OZU|rcsb pdb:2RC4|rcsb pdb:3V43|rcsb pdb:4LJN|rcsb pdb:4LK9|rcsb pdb:4LKA|rcsb pdb:4LLB|rcsb pdb:5B75|rcsb pdb:5B76|rcsb pdb:5B77|rcsb pdb:5B78|rcsb pdb:6LSB|reactome:R-HSA-3214847|reactome:R-HSA-6804758 - - comment:"author score: 65" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dwJLwzNcL9866noaSFznDKeulRU9606 rogid:jPgi03a1G13Lv1IjZOz9vz1FvcY9606 rigid:RzUUSQ1owOEVdFCnvd9TBScYx94 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WYH8 uniprotkb:Q8WYB5 intact:EBI-488533|uniprotkb:Q9BS30|uniprotkb:A8K1P3|uniprotkb:Q53NU6|uniprotkb:Q57Z54|ensembl:ENSP00000322142 intact:EBI-948029|uniprotkb:O15087|uniprotkb:Q86Y05|uniprotkb:Q8WU81|uniprotkb:Q9UKW2|uniprotkb:Q9UKW3|uniprotkb:Q9UKX0|ensembl:ENSP00000287239|ensembl:ENSP00000486595|ensembl:ENSP00000497166|ensembl:ENSP00000497352|ensembl:ENSP00000497718|ensembl:ENSP00000497841 psi-mi:ing5_human(display_long)|uniprotkb:p28ING5(gene name synonym)|uniprotkb:ING5(gene name)|psi-mi:ING5(display_short) psi-mi:kat6b_human(display_long)|uniprotkb:MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4(gene name synonym)|uniprotkb:Histone acetyltransferase MOZ2(gene name synonym)|uniprotkb:Monocytic leukemia zinc finger protein-related factor(gene name synonym)|uniprotkb:KAT6B(gene name)|psi-mi:KAT6B(display_short)|uniprotkb:MYST4(gene name synonym)|uniprotkb:KIAA0383(gene name synonym)|uniprotkb:MORF(gene name synonym)|uniprotkb:MOZ2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479561|imex:IM-26985-549 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115705.2|ensembl:ENSG00000168395(gene)|ensembl:ENST00000313552(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006260"(DNA replication)|go:"GO:0006473"(protein acetylation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028638|interpro:IPR028651|mint:Q8WYH8|rcsb pdb:3C6W|rcsb pdb:5ME8|rcsb pdb:5MTO|reactome:R-HSA-3214847|reactome:R-HSA-6804758|refseq:NP_001317091.1|dip:DIP-32511N refseq:NP_036462.2|refseq:NP_001243397.1|refseq:NP_001243398.1|refseq:XP_005269721.1|ensembl:ENSP00000287239|ensembl:ENST00000372711|ensembl:ENSP00000361796|ensembl:ENST00000372714|ensembl:ENSP00000361799|ensembl:ENST00000372724|ensembl:ENSP00000361809|ensembl:ENST00000372725|ensembl:ENSP00000361810|ensembl:ENST00000628038|ensembl:ENSP00000485896|ensembl:ENST00000628523|ensembl:ENSP00000487238|ensembl:ENST00000629233|ensembl:ENSP00000487219|ensembl:ENST00000629879|ensembl:ENSP00000486731|ensembl:ENSP00000486595|ensembl:ENSP00000497352|ensembl:ENSP00000497718|ensembl:ENSP00000497841|ensembl:ENST00000648892|ensembl:ENSP00000497048|ensembl:ENST00000649006|ensembl:ENSP00000498139|ensembl:ENSP00000497166|ensembl:ENST00000649574|ensembl:ENSP00000497416|ensembl:ENST00000650575|ensembl:ENSP00000497453|refseq:XP_016871489.1|refseq:XP_016871490.1|refseq:XP_016871491.1|refseq:XP_016871492.1|refseq:XP_016871494.1|refseq:XP_016871495.1|refseq:XP_016871496.1|refseq:XP_016871497.1|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR005818(Histone H1/H5)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR019787|interpro:IPR036388|interpro:IPR036390|interpro:IPR040706|mint:Q8WYB5|interpro:IPR001965(Zinc finger, PHD-type)|rcsb pdb:5U2J|rcsb pdb:6OIE|reactome:R-HSA-3214847|ensembl:ENSG00000281813(gene)|ensembl:ENST00000287239(transcript)|ensembl:ENST00000630001(transcript)|ensembl:ENST00000647630(transcript)|ensembl:ENST00000648605(transcript)|ensembl:ENST00000648725(transcript)|ensembl:ENST00000649463(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|ensembl:ENSG00000156650(gene)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex) - - comment:"author score: 70" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dwJLwzNcL9866noaSFznDKeulRU9606 rogid:SQZ29f1Wqak9s8f4A1mrKmfToU09606 rigid:RzUUSQ1owOEVdFCnvd9TBScYx94 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WYH8 uniprotkb:P55201 intact:EBI-488533|uniprotkb:Q9BS30|uniprotkb:A8K1P3|uniprotkb:Q53NU6|uniprotkb:Q57Z54|ensembl:ENSP00000322142 intact:EBI-2837428|uniprotkb:Q9UHI0|uniprotkb:Q8TCM6|uniprotkb:B4DEZ6|uniprotkb:Q7Z6E0|ensembl:ENSP00000507469 psi-mi:ing5_human(display_long)|uniprotkb:p28ING5(gene name synonym)|uniprotkb:ING5(gene name)|psi-mi:ING5(display_short) psi-mi:brpf1_human(display_long)|uniprotkb:BRPF1(gene name)|psi-mi:BRPF1(display_short)|uniprotkb:BR140(gene name synonym)|uniprotkb:Bromodomain and PHD finger-containing protein 1(gene name synonym)|uniprotkb:Protein Br140(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479561|imex:IM-26985-549 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115705.2|ensembl:ENSG00000168395(gene)|ensembl:ENST00000313552(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006260"(DNA replication)|go:"GO:0006473"(protein acetylation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028638|interpro:IPR028651|mint:Q8WYH8|rcsb pdb:3C6W|rcsb pdb:5ME8|rcsb pdb:5MTO|reactome:R-HSA-3214847|reactome:R-HSA-6804758|refseq:NP_001317091.1|dip:DIP-32511N refseq:NP_001003694.1|refseq:NP_004625.2|refseq:NP_001305978.1|refseq:NP_001305979.1|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042008|interpro:IPR042061|mint:P55201|rcsb pdb:2D9E|rcsb pdb:2RS9|rcsb pdb:2X35|rcsb pdb:2X4W|rcsb pdb:2X4X|interpro:IPR001487(Bromodomain)|rcsb pdb:2X4Y|rcsb pdb:3MO8|rcsb pdb:4LC2|rcsb pdb:4QYD|rcsb pdb:4QYL|rcsb pdb:4UYE|rcsb pdb:5C6S|rcsb pdb:5C7N|rcsb pdb:5C85|rcsb pdb:5C87|rcsb pdb:5C89|rcsb pdb:5D7X|rcsb pdb:5DY7|rcsb pdb:5DYA|rcsb pdb:5DYC|rcsb pdb:5E3D|rcsb pdb:5E3G|rcsb pdb:5EM3|rcsb pdb:5EPR|rcsb pdb:5EPS|rcsb pdb:3L42|rcsb pdb:5EQ1|rcsb pdb:5ERC|ensembl:ENSG00000156983(gene)|ensembl:ENST00000683743(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010698"(acetyltransferase activator activity)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|rcsb pdb:5ETB|rcsb pdb:5ETD|rcsb pdb:5EV9|rcsb pdb:5EVA|rcsb pdb:5OWE|rcsb pdb:5EWC|rcsb pdb:5T4U|rcsb pdb:5EWD|rcsb pdb:5EWH|rcsb pdb:5EWV|rcsb pdb:5EWW|rcsb pdb:5FFV|rcsb pdb:5FFW|rcsb pdb:5FFY|rcsb pdb:5FG4|rcsb pdb:5FG5|rcsb pdb:5G4R|rcsb pdb:5G4S|rcsb pdb:5MWG|rcsb pdb:5MWH|rcsb pdb:5MWZ|rcsb pdb:5MYG|rcsb pdb:5O4S|rcsb pdb:5O4T|rcsb pdb:5O55|rcsb pdb:5O5A|rcsb pdb:5O5F|rcsb pdb:5O5H|rcsb pdb:5OV8|rcsb pdb:5OWA|rcsb pdb:5OWB|rcsb pdb:6EKQ|rcsb pdb:6U04|rcsb pdb:7C4I|reactome:R-HSA-3214847|reactome:R-HSA-6804758|rcsb pdb:5T4V|dip:DIP-59001N - - comment:"author score: 74" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dwJLwzNcL9866noaSFznDKeulRU9606 rogid:+sZdYbyk1/VdG0qCF2CL3h1liVw9606 rigid:RzUUSQ1owOEVdFCnvd9TBScYx94 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WYH8 uniprotkb:O95251 intact:EBI-488533|uniprotkb:Q9BS30|uniprotkb:A8K1P3|uniprotkb:Q53NU6|uniprotkb:Q57Z54|ensembl:ENSP00000322142 intact:EBI-473199|uniprotkb:B3KN74|uniprotkb:B4DFB4|uniprotkb:B4DFE0|uniprotkb:B4DF85|uniprotkb:B4DGY4|uniprotkb:E7ER15|uniprotkb:G5E9K7|intact:EBI-10986821|ensembl:ENSP00000259021 psi-mi:ing5_human(display_long)|uniprotkb:p28ING5(gene name synonym)|uniprotkb:ING5(gene name)|psi-mi:ING5(display_short) psi-mi:kat7_human(display_long)|uniprotkb:KAT7(gene name)|psi-mi:KAT7(display_short)|uniprotkb:HBO1(gene name synonym)|uniprotkb:HBOa(gene name synonym)|uniprotkb:MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2(gene name synonym)|uniprotkb:Histone acetyltransferase binding to ORC1(gene name synonym)|uniprotkb:MYST2(gene name synonym)|uniprotkb:Lysine acetyltransferase 7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479561|imex:IM-26985-549 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115705.2|ensembl:ENSG00000168395(gene)|ensembl:ENST00000313552(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006260"(DNA replication)|go:"GO:0006473"(protein acetylation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028638|interpro:IPR028651|mint:Q8WYH8|rcsb pdb:3C6W|rcsb pdb:5ME8|rcsb pdb:5MTO|reactome:R-HSA-3214847|reactome:R-HSA-6804758|refseq:NP_001317091.1|dip:DIP-32511N refseq:NP_001186084.1|refseq:NP_001186085.1|refseq:NP_001186086.1|refseq:NP_001186087.1|refseq:NP_008998.1|dip:DIP-29697N|ensembl:ENSG00000136504(gene)|ensembl:ENST00000259021(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031098"(stress-activated protein kinase signaling cascade)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0036409"(histone H3-K14 acetyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0072708"(response to sorbitol)|go:"GO:0072710"(response to hydroxyurea)|go:"GO:0072716"(response to actinomycin D)|go:"GO:0072720"(response to dithiothreitol)|go:"GO:0072739"(response to anisomycin)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:0090734"(site of DNA damage)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902035"(positive regulation of hematopoietic stem cell proliferation)|go:"GO:2000819"(regulation of nucleotide-excision repair)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR036060|interpro:IPR036388|interpro:IPR040706|mint:O95251|rcsb pdb:5GK9|rcsb pdb:6MAJ|rcsb pdb:6MAK|reactome:R-HSA-3214847 - - comment:"author score: 83" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dwJLwzNcL9866noaSFznDKeulRU9606 rogid:K27pgvPEe1/+rZXYUkPfMY7PZMs9606 rigid:RzUUSQ1owOEVdFCnvd9TBScYx94 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WYH8 uniprotkb:O95696 intact:EBI-488533|uniprotkb:Q9BS30|uniprotkb:A8K1P3|uniprotkb:Q53NU6|uniprotkb:Q57Z54|ensembl:ENSP00000322142 intact:EBI-714754|uniprotkb:A6ZJA4|ensembl:ENSP00000216267|ensembl:ENSP00000384076 psi-mi:ing5_human(display_long)|uniprotkb:p28ING5(gene name synonym)|uniprotkb:ING5(gene name)|psi-mi:ING5(display_short) psi-mi:brd1_human(display_long)|uniprotkb:BR140-like protein(gene name synonym)|uniprotkb:BRD1(gene name)|psi-mi:BRD1(display_short)|uniprotkb:BRL(gene name synonym)|uniprotkb:BRPF2(gene name synonym)|uniprotkb:Bromodomain and PHD finger-containing protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479561|imex:IM-26985-549 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115705.2|ensembl:ENSG00000168395(gene)|ensembl:ENST00000313552(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006260"(DNA replication)|go:"GO:0006473"(protein acetylation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028638|interpro:IPR028651|mint:Q8WYH8|rcsb pdb:3C6W|rcsb pdb:5ME8|rcsb pdb:5MTO|reactome:R-HSA-3214847|reactome:R-HSA-6804758|refseq:NP_001317091.1|dip:DIP-32511N go:"GO:0036409"(histone H3-K14 acetyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051602"(response to electrical stimulus)|ensembl:ENSG00000100425(gene)|ensembl:ENST00000216267(transcript)|ensembl:ENST00000404034(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0016607"(nuclear speck)|go:"GO:0030425"(dendrite)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018359|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR035502|interpro:IPR036427|interpro:IPR042004|interpro:IPR042009|mint:O95696|rcsb pdb:2KU3|rcsb pdb:2L43|rcsb pdb:2LQ6|rcsb pdb:3LYI|rcsb pdb:3RCW|rcsb pdb:4Z02|rcsb pdb:5AME|rcsb pdb:5AMF|rcsb pdb:5FG6|rcsb pdb:5GK9|rcsb pdb:5N49|rcsb pdb:5PNX|rcsb pdb:5PNY|rcsb pdb:5PNZ|rcsb pdb:5PO0|rcsb pdb:5PO1|rcsb pdb:5PO2|rcsb pdb:5PO3|rcsb pdb:5PO4|rcsb pdb:5PO5|rcsb pdb:5PO6|rcsb pdb:5PO7|rcsb pdb:5PO8|rcsb pdb:5PO9|rcsb pdb:5POA|rcsb pdb:5POB|rcsb pdb:5POC|rcsb pdb:5POD|rcsb pdb:5POE|rcsb pdb:5POF|rcsb pdb:5POG|rcsb pdb:5POH|rcsb pdb:5POI|rcsb pdb:5POJ|rcsb pdb:5POK|rcsb pdb:5POL|rcsb pdb:5POM|rcsb pdb:5PON|rcsb pdb:5POO|rcsb pdb:5POP|rcsb pdb:5POQ|refseq:XP_016884206.1|rcsb pdb:5POR|rcsb pdb:5POS|rcsb pdb:5POT|rcsb pdb:5POU|rcsb pdb:5POV|rcsb pdb:5POW|rcsb pdb:5POX|rcsb pdb:5POY|rcsb pdb:5POZ|rcsb pdb:5PP0|rcsb pdb:5PP1|rcsb pdb:5PP2|rcsb pdb:5PP3|rcsb pdb:5PP4|rcsb pdb:5PP5|rcsb pdb:5PP6|rcsb pdb:5PP7|rcsb pdb:5PP8|rcsb pdb:5PP9|rcsb pdb:5PPA|rcsb pdb:5PPB|rcsb pdb:5PPC|rcsb pdb:5PPD|rcsb pdb:5PPE|rcsb pdb:5PPF|rcsb pdb:5PPG|rcsb pdb:5PPH|rcsb pdb:5PPI|rcsb pdb:5PPJ|rcsb pdb:5PPK|rcsb pdb:5PPL|rcsb pdb:5PPM|rcsb pdb:5PPN|rcsb pdb:5PPO|rcsb pdb:5PPP|rcsb pdb:5PPQ|rcsb pdb:5PPR|rcsb pdb:5PPS|rcsb pdb:5PPT|rcsb pdb:5PPU|rcsb pdb:5PPV|rcsb pdb:5PPW|rcsb pdb:5PPX|rcsb pdb:5PPY|rcsb pdb:5PPZ|rcsb pdb:5PQ0|rcsb pdb:5PQ1|rcsb pdb:5PQ2|rcsb pdb:5PQ3|rcsb pdb:5PQ4|rcsb pdb:5PQ5|rcsb pdb:5PQ6|rcsb pdb:5PQ7|rcsb pdb:5PQ8|rcsb pdb:5PQ9|rcsb pdb:5PQA|rcsb pdb:5PQB|rcsb pdb:5PQC|rcsb pdb:5PQD|rcsb pdb:5PQE|rcsb pdb:5PQF|rcsb pdb:5PQG|rcsb pdb:5PQH|rcsb pdb:5PQI|rcsb pdb:5PQJ|rcsb pdb:5PQK|rcsb pdb:5PQL|rcsb pdb:5PQM|rcsb pdb:5PQN|rcsb pdb:5PQO|rcsb pdb:5PQP|rcsb pdb:5PQQ|rcsb pdb:5PQR|rcsb pdb:5PQS|rcsb pdb:5PQT|rcsb pdb:5PQU|rcsb pdb:5PQV|rcsb pdb:5PQW|rcsb pdb:5PQX|rcsb pdb:5PQY|rcsb pdb:5PQZ|rcsb pdb:5PR0|rcsb pdb:5PR1|rcsb pdb:5PR2|rcsb pdb:5PR4|rcsb pdb:5PR5|rcsb pdb:5PR6|rcsb pdb:5PR7|rcsb pdb:5PR8|rcsb pdb:5PST|rcsb pdb:5PR9|rcsb pdb:5PRA|rcsb pdb:5PRB|rcsb pdb:5PRD|rcsb pdb:5PRE|rcsb pdb:5PRF|rcsb pdb:5PRG|rcsb pdb:5PRH|rcsb pdb:5PRI|rcsb pdb:5PRJ|rcsb pdb:5PRK|rcsb pdb:5PRL|rcsb pdb:5PRM|rcsb pdb:5PRO|rcsb pdb:5PRP|rcsb pdb:5PRQ|rcsb pdb:5PRR|rcsb pdb:5PRS|rcsb pdb:5PRT|rcsb pdb:5PRU|rcsb pdb:5PRV|rcsb pdb:5PRW|rcsb pdb:5PRX|rcsb pdb:5PRY|rcsb pdb:5PRZ|rcsb pdb:5PS0|rcsb pdb:5PS1|rcsb pdb:5PS2|rcsb pdb:5PS3|rcsb pdb:5PS4|rcsb pdb:5PS5|rcsb pdb:5PS6|rcsb pdb:5PS7|rcsb pdb:5PS8|rcsb pdb:5PS9|rcsb pdb:5PSA|rcsb pdb:5PSB|rcsb pdb:5PSC|rcsb pdb:5PSD|rcsb pdb:5PSE|rcsb pdb:5PSF|rcsb pdb:5PSG|rcsb pdb:5PSH|rcsb pdb:5PSI|rcsb pdb:5PSJ|rcsb pdb:5PSK|rcsb pdb:5PSL|rcsb pdb:5PSM|rcsb pdb:5PSN|rcsb pdb:5PSO|rcsb pdb:5PSP|rcsb pdb:5PSQ|rcsb pdb:5PSR|rcsb pdb:5PSS|rcsb pdb:5PSU|rcsb pdb:5PSV|rcsb pdb:5PSW|rcsb pdb:5PSX|rcsb pdb:5PSY|rcsb pdb:5PSZ|rcsb pdb:5PT0|rcsb pdb:5PT1|rcsb pdb:5PT2|rcsb pdb:5PT3|rcsb pdb:5PT4|rcsb pdb:5PT5|rcsb pdb:5PT6|rcsb pdb:5PT7|rcsb pdb:5PT8|rcsb pdb:5PT9|rcsb pdb:5PTA|rcsb pdb:5PTB|rcsb pdb:5PTC|rcsb pdb:5PTE|rcsb pdb:5PTF|rcsb pdb:5PTG|rcsb pdb:5PTH|rcsb pdb:5PTJ|rcsb pdb:5PTK|rcsb pdb:5PTL|rcsb pdb:5PTM|rcsb pdb:5PTN|rcsb pdb:5PTO|rcsb pdb:5PTQ|rcsb pdb:5PTR|rcsb pdb:5PTS|rcsb pdb:5PTT|rcsb pdb:5PTU|rcsb pdb:5PTV|rcsb pdb:5PTW|rcsb pdb:5PTX|rcsb pdb:5PTY|rcsb pdb:5PTZ|rcsb pdb:5PU0|rcsb pdb:5PU1|rcsb pdb:5PU2|rcsb pdb:5PU3|rcsb pdb:5PU4|rcsb pdb:5PU5|rcsb pdb:5PU6|rcsb pdb:5PU7|rcsb pdb:5PU8|rcsb pdb:5PU9|rcsb pdb:5PUA|rcsb pdb:5PUB|rcsb pdb:5PUC|rcsb pdb:5PUD|rcsb pdb:5PUE|rcsb pdb:5PUF|rcsb pdb:5PUG|rcsb pdb:5PUH|rcsb pdb:5PUI|rcsb pdb:5PUJ|rcsb pdb:5PUK|rcsb pdb:5PUL|rcsb pdb:5PUM|rcsb pdb:5PUN|rcsb pdb:5PUO|rcsb pdb:5PUP|rcsb pdb:5PUQ|rcsb pdb:5PUR|rcsb pdb:5PUS|rcsb pdb:5PUT|rcsb pdb:5PUU|rcsb pdb:5PUV|rcsb pdb:5PUW|rcsb pdb:5PUX|rcsb pdb:5PUY|rcsb pdb:5PUZ|rcsb pdb:5PV0|rcsb pdb:5PV1|rcsb pdb:5PV2|rcsb pdb:5PV3|rcsb pdb:5PV4|rcsb pdb:5PV5|rcsb pdb:5PV6|rcsb pdb:5PV7|rcsb pdb:5PV8|rcsb pdb:5PV9|rcsb pdb:5PVA|rcsb pdb:5PVB|rcsb pdb:5PVC|rcsb pdb:5PVD|rcsb pdb:5PVE|rcsb pdb:5PVF|rcsb pdb:5PVG|rcsb pdb:5PVH|rcsb pdb:5PVI|rcsb pdb:5PVJ|rcsb pdb:5PVK|rcsb pdb:5PVL|rcsb pdb:5PVM|rcsb pdb:5PVN|rcsb pdb:5PVO|rcsb pdb:5PVP|rcsb pdb:5PVQ|rcsb pdb:5PVR|rcsb pdb:5PVS|rcsb pdb:5PVT|rcsb pdb:5PVU|rcsb pdb:5PVV|rcsb pdb:5PVW|rcsb pdb:5PVX|rcsb pdb:5PVY|rcsb pdb:5PVZ|rcsb pdb:5PW0|rcsb pdb:5PW1|rcsb pdb:5PW2|rcsb pdb:5PW3|rcsb pdb:5PW4|rcsb pdb:5PW5|rcsb pdb:5PW6|rcsb pdb:5PW7|rcsb pdb:5PW8|rcsb pdb:5PW9|rcsb pdb:5PWA|rcsb pdb:5PWB|rcsb pdb:6IN2|rcsb pdb:6MAJ|rcsb pdb:6MAK|rcsb pdb:7LH9|reactome:R-HSA-3214847|reactome:R-HSA-6804758|refseq:NP_001291737.1|refseq:NP_001291738.1|refseq:XP_016884204.1|refseq:XP_016884205.1 - - comment:"author score: 134" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dwJLwzNcL9866noaSFznDKeulRU9606 rogid:P/L2yjwT2CYr7rO64cYcdahm2z09606 rigid:RzUUSQ1owOEVdFCnvd9TBScYx94 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WYH8 uniprotkb:Q9HAF1 intact:EBI-488533|uniprotkb:Q9BS30|uniprotkb:A8K1P3|uniprotkb:Q53NU6|uniprotkb:Q57Z54|ensembl:ENSP00000322142 intact:EBI-399266|uniprotkb:B1AK64|uniprotkb:Q4F967|uniprotkb:Q7Z311|uniprotkb:Q86WE3|ensembl:ENSP00000296214 psi-mi:ing5_human(display_long)|uniprotkb:p28ING5(gene name synonym)|uniprotkb:ING5(gene name)|psi-mi:ING5(display_short) psi-mi:eaf6_human(display_long)|uniprotkb:Sarcoma antigen NY-SAR-91(gene name synonym)|uniprotkb:MEAF6(gene name)|psi-mi:MEAF6(display_short)|uniprotkb:EAF6(gene name synonym)|uniprotkb:Esa1-associated factor 6 homolog(gene name synonym)|uniprotkb:C1orf149(gene name synonym)|uniprotkb:CENP-28(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479561|imex:IM-26985-549 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_115705.2|ensembl:ENSG00000168395(gene)|ensembl:ENST00000313552(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006260"(DNA replication)|go:"GO:0006473"(protein acetylation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045926"(negative regulation of growth)|go:"GO:0046872"(metal ion binding)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR024610|interpro:IPR028638|interpro:IPR028651|mint:Q8WYH8|rcsb pdb:3C6W|rcsb pdb:5ME8|rcsb pdb:5MTO|reactome:R-HSA-3214847|reactome:R-HSA-6804758|refseq:NP_001317091.1|dip:DIP-32511N refseq:NP_001257804.1|refseq:NP_073593.2|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0043972"(histone H3-K23 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0070776"(MOZ/MORF histone acetyltransferase complex)|go:"GO:1990467"(NuA3a histone acetyltransferase complex)|go:"GO:1990468"(NuA3b histone acetyltransferase complex)|interpro:IPR015418(Histone H4 acetyltransferase, NuA4 complex, Eaf6)|mint:Q9HAF1|reactome:R-HSA-3214847|reactome:R-HSA-6804758|ensembl:ENSG00000163875(gene)|ensembl:ENST00000296214(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|refseq:NP_001257805.1 - - comment:"author score: 134" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dwJLwzNcL9866noaSFznDKeulRU9606 rogid:v0eU3uwnLihcUQhLKYma3WIhofk9606 rigid:RzUUSQ1owOEVdFCnvd9TBScYx94 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVR2 uniprotkb:P84090 intact:EBI-536703|uniprotkb:Q6IA93|uniprotkb:Q7L538|uniprotkb:Q7L8C8|uniprotkb:Q9H3W8|ensembl:ENSP00000381064 intact:EBI-711389|uniprotkb:P70659|uniprotkb:Q14259|ensembl:ENSP00000451080|uniprotkb:B2R5H2 psi-mi:int10_human(display_long)|uniprotkb:INTS10(gene name)|psi-mi:INTS10(display_short)|uniprotkb:C8orf35(gene name synonym) psi-mi:erh_human(display_long)|uniprotkb:ERH(gene name)|psi-mi:ERH(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479600|imex:IM-26985-171 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR026164|mint:Q9NVR2|reactome:R-HSA-6807505|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000104613(gene)|ensembl:ENST00000397977(transcript)|go:"GO:0005634"(nucleus)|refseq:NP_060612.2|dip:DIP-34063N ensembl:ENSG00000100632(gene)|ensembl:ENST00000557016(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006213"(pyrimidine nucleoside metabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0030496"(midbody)|go:"GO:0034709"(methylosome)|interpro:IPR000781(Enhancer of rudimentary)|interpro:IPR035912|mint:P84090|rcsb pdb:1W9G|rcsb pdb:2NML|rcsb pdb:7CNC|refseq:NP_004441.1|dip:DIP-42473N - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:fGpdHHtp91cTl+TFPeZy7loLAE49606 rogid:foMOmvZ9wQyH0rrzBB2YlQhrT0g9606 rigid:BESubCtaRB97u3J+u7SZNoukoSQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVR2 uniprotkb:Q9NVM9 intact:EBI-536703|uniprotkb:Q6IA93|uniprotkb:Q7L538|uniprotkb:Q7L8C8|uniprotkb:Q9H3W8|ensembl:ENSP00000381064 intact:EBI-741429|uniprotkb:Q86WE2|uniprotkb:Q96HM2|uniprotkb:Q9BTX2|uniprotkb:Q9NTB6|uniprotkb:Q9NVM5|ensembl:ENSP00000261191|uniprotkb:B4DNK1 psi-mi:int10_human(display_long)|uniprotkb:INTS10(gene name)|psi-mi:INTS10(display_short)|uniprotkb:C8orf35(gene name synonym) psi-mi:int13_human(display_long)|uniprotkb:INTS13(gene name)|psi-mi:INTS13(display_short)|uniprotkb:ASUN(gene name synonym)|uniprotkb:C12orf11(gene name synonym)|uniprotkb:Cell cycle regulator Mat89Bb homolog(gene name synonym)|uniprotkb:GCT1(gene name synonym)|uniprotkb:Germ cell tumor 1(gene name synonym)|uniprotkb:Protein asunder homolog(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-95(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479600|imex:IM-26985-171 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR026164|mint:Q9NVR2|reactome:R-HSA-6807505|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000104613(gene)|ensembl:ENST00000397977(transcript)|go:"GO:0005634"(nucleus)|refseq:NP_060612.2|dip:DIP-34063N refseq:NP_060634.2|ensembl:ENSG00000064102(gene)|ensembl:ENST00000261191(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0032039"(integrator complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051301"(cell division)|go:"GO:0051642"(centrosome localization)|go:"GO:0080154"(regulation of fertilization)|go:"GO:0090435"(protein localization to nuclear envelope)|interpro:IPR019355|mint:Q9NVM9|rcsb pdb:6SN1|reactome:R-HSA-6807505|refseq:XP_016875121.1 - - comment:"author score: 91" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:fGpdHHtp91cTl+TFPeZy7loLAE49606 rogid:UXjIqkQso+2g8N+pfFjZVKjbJ509606 rigid:BESubCtaRB97u3J+u7SZNoukoSQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVR2 uniprotkb:Q96SY0 intact:EBI-536703|uniprotkb:Q6IA93|uniprotkb:Q7L538|uniprotkb:Q7L8C8|uniprotkb:Q9H3W8|ensembl:ENSP00000381064 intact:EBI-4409724|uniprotkb:Q49AH8|uniprotkb:Q96HX5|uniprotkb:Q9H0S5|uniprotkb:B4DDI6|uniprotkb:B4DVD5|ensembl:ENSP00000326379 psi-mi:int10_human(display_long)|uniprotkb:INTS10(gene name)|psi-mi:INTS10(display_short)|uniprotkb:C8orf35(gene name synonym) psi-mi:int14_human(display_long)|uniprotkb:VWA9(gene name synonym)|uniprotkb:INTS14(gene name)|psi-mi:INTS14(display_short)|uniprotkb:C15orf44(gene name synonym)|uniprotkb:von Willebrand factor A domain-containing protein 9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479600|imex:IM-26985-171 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0016180"(snRNA processing)|go:"GO:0032039"(integrator complex)|interpro:IPR026164|mint:Q9NVR2|reactome:R-HSA-6807505|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000104613(gene)|ensembl:ENST00000397977(transcript)|go:"GO:0005634"(nucleus)|refseq:NP_060612.2|dip:DIP-34063N refseq:NP_001129515.1|refseq:XP_011520403.1|refseq:NP_001193987.1|refseq:NP_001193988.1|refseq:XP_006720772.1|refseq:XP_006720774.1|refseq:XP_016878133.1|ensembl:ENSG00000138614(gene)|ensembl:ENST00000313182(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0032039"(integrator complex)|go:"GO:0034472"(snRNA 3'-end processing)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR036465|interpro:IPR039841|mint:Q96SY0|rcsb pdb:6SN1|reactome:R-HSA-6807505 - - comment:"author score: 111" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:fGpdHHtp91cTl+TFPeZy7loLAE49606 rogid:a1H+KgPggyxgI/jQfUR68x6X8iI9606 rigid:BESubCtaRB97u3J+u7SZNoukoSQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y2K7 uniprotkb:P62805 intact:EBI-765758|ensembl:ENSP00000432786|uniprotkb:Q49A21|uniprotkb:Q4G0M3|uniprotkb:Q69YY8|uniprotkb:Q9BVH5|uniprotkb:Q9H7H5|uniprotkb:Q9UK66|uniprotkb:D4QA03|uniprotkb:E9PIL6|uniprotkb:I3VM55 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:kdm2a_human(display_long)|uniprotkb:CXXC8(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1A(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 11(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 11(gene name synonym)|uniprotkb:F-box protein FBL7(gene name synonym)|uniprotkb:F-box protein Lilina(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 8(gene name synonym)|uniprotkb:KDM2A(gene name)|psi-mi:KDM2A(display_short)|uniprotkb:FBL7(gene name synonym)|uniprotkb:KIAA1004(gene name synonym)|uniprotkb:JHDM1A(gene name synonym)|uniprotkb:FBXL11(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1A(gene name synonym)|uniprotkb:FBL11(gene name synonym) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479780|imex:IM-26985-407 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000173120(gene)|ensembl:ENST00000529006(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0032452"(histone demethylase activity)|refseq:NP_036440.1|refseq:XP_011543163.1|refseq:NP_001243334.1|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR032675|mint:Q9Y2K7|rcsb pdb:2YU1|rcsb pdb:2YU2|rcsb pdb:4BBQ|rcsb pdb:6BYH|rcsb pdb:6C16|reactome:R-HSA-3214842|interpro:IPR041070|dip:DIP-34596N ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FWcxfQykne+IrmtpDxZ218sEURc9606 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 rigid:dH9v945KNOHsg0YevHh7DhGHozU false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y2K7 uniprotkb:Q92522 intact:EBI-765758|ensembl:ENSP00000432786|uniprotkb:Q49A21|uniprotkb:Q4G0M3|uniprotkb:Q69YY8|uniprotkb:Q9BVH5|uniprotkb:Q9H7H5|uniprotkb:Q9UK66|uniprotkb:D4QA03|uniprotkb:E9PIL6|uniprotkb:I3VM55 intact:EBI-876335|ensembl:ENSP00000329662 psi-mi:kdm2a_human(display_long)|uniprotkb:CXXC8(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1A(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 11(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 11(gene name synonym)|uniprotkb:F-box protein FBL7(gene name synonym)|uniprotkb:F-box protein Lilina(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 8(gene name synonym)|uniprotkb:KDM2A(gene name)|psi-mi:KDM2A(display_short)|uniprotkb:FBL7(gene name synonym)|uniprotkb:KIAA1004(gene name synonym)|uniprotkb:JHDM1A(gene name synonym)|uniprotkb:FBXL11(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1A(gene name synonym)|uniprotkb:FBL11(gene name synonym) psi-mi:h1x_human(display_long)|uniprotkb:H1-10(gene name)|psi-mi:H1-10(display_short)|uniprotkb:H1FX(gene name synonym)|uniprotkb:Histone H1x(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479780|imex:IM-26985-407 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000173120(gene)|ensembl:ENST00000529006(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0032452"(histone demethylase activity)|refseq:NP_036440.1|refseq:XP_011543163.1|refseq:NP_001243334.1|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR032675|mint:Q9Y2K7|rcsb pdb:2YU1|rcsb pdb:2YU2|rcsb pdb:4BBQ|rcsb pdb:6BYH|rcsb pdb:6C16|reactome:R-HSA-3214842|interpro:IPR041070|dip:DIP-34596N ensembl:ENSG00000184897(gene)|ensembl:ENST00000333762(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045296"(cadherin binding)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:Q92522|refseq:NP_006017.1|dip:DIP-36358N|rcsb pdb:2LSO|rcsb pdb:6L9Z|rcsb pdb:7K60|rcsb pdb:7K63 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FWcxfQykne+IrmtpDxZ218sEURc9606 rogid:T+NweCoHXj0rYsS6gJ4V42R9MpA9606 rigid:dH9v945KNOHsg0YevHh7DhGHozU false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y2K7 uniprotkb:P62917 intact:EBI-765758|ensembl:ENSP00000432786|uniprotkb:Q49A21|uniprotkb:Q4G0M3|uniprotkb:Q69YY8|uniprotkb:Q9BVH5|uniprotkb:Q9H7H5|uniprotkb:Q9UK66|uniprotkb:D4QA03|uniprotkb:E9PIL6|uniprotkb:I3VM55 intact:EBI-438527|ensembl:ENSP00000262584|ensembl:ENSP00000378378|ensembl:ENSP00000433464|uniprotkb:P25120|uniprotkb:Q567Q7|uniprotkb:Q969V7|uniprotkb:Q9BWQ9|uniprotkb:A8K094|uniprotkb:D3DWN2 psi-mi:kdm2a_human(display_long)|uniprotkb:CXXC8(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1A(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 11(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 11(gene name synonym)|uniprotkb:F-box protein FBL7(gene name synonym)|uniprotkb:F-box protein Lilina(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 8(gene name synonym)|uniprotkb:KDM2A(gene name)|psi-mi:KDM2A(display_short)|uniprotkb:FBL7(gene name synonym)|uniprotkb:KIAA1004(gene name synonym)|uniprotkb:JHDM1A(gene name synonym)|uniprotkb:FBXL11(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1A(gene name synonym)|uniprotkb:FBL11(gene name synonym) psi-mi:rl8_human(display_long)|uniprotkb:RPL8(gene name)|psi-mi:RPL8(display_short)|uniprotkb:Large ribosomal subunit protein uL2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479780|imex:IM-26985-407 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000173120(gene)|ensembl:ENST00000529006(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0032452"(histone demethylase activity)|refseq:NP_036440.1|refseq:XP_011543163.1|refseq:NP_001243334.1|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR032675|mint:Q9Y2K7|rcsb pdb:2YU1|rcsb pdb:2YU2|rcsb pdb:4BBQ|rcsb pdb:6BYH|rcsb pdb:6C16|reactome:R-HSA-3214842|interpro:IPR041070|dip:DIP-34596N rcsb pdb:4CCN|rcsb pdb:4CCO|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:4Y3O|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000161016(gene)|ensembl:ENST00000262584(transcript)|ensembl:ENST00000394920(transcript)|ensembl:ENST00000528957(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0098794"(postsynapse)|interpro:IPR002171(Ribosomal protein L2)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR014726(Ribosomal protein L2, domain 3)|interpro:IPR022666|interpro:IPR022669|interpro:IPR022671|interpro:IPR023672|mint:P62917|rcsb pdb:4CCM|refseq:NP_000964.1|refseq:NP_150644.1|refseq:NP_001304700.1|refseq:NP_001304711.1|dip:DIP-37967N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FWcxfQykne+IrmtpDxZ218sEURc9606 rogid:+b/ORzdCy/nqFLsKRV9VhIZgdjg9606 rigid:dH9v945KNOHsg0YevHh7DhGHozU false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y2K7 uniprotkb:Q13257 intact:EBI-765758|ensembl:ENSP00000432786|uniprotkb:Q49A21|uniprotkb:Q4G0M3|uniprotkb:Q69YY8|uniprotkb:Q9BVH5|uniprotkb:Q9H7H5|uniprotkb:Q9UK66|uniprotkb:D4QA03|uniprotkb:E9PIL6|uniprotkb:I3VM55 intact:EBI-78203|intact:EBI-28969404|ensembl:ENSP00000296509|uniprotkb:Q53F56|uniprotkb:Q548X9|uniprotkb:Q6IRW7|uniprotkb:Q8IZX3 psi-mi:kdm2a_human(display_long)|uniprotkb:CXXC8(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1A(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 11(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 11(gene name synonym)|uniprotkb:F-box protein FBL7(gene name synonym)|uniprotkb:F-box protein Lilina(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 8(gene name synonym)|uniprotkb:KDM2A(gene name)|psi-mi:KDM2A(display_short)|uniprotkb:FBL7(gene name synonym)|uniprotkb:KIAA1004(gene name synonym)|uniprotkb:JHDM1A(gene name synonym)|uniprotkb:FBXL11(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1A(gene name synonym)|uniprotkb:FBL11(gene name synonym) psi-mi:md2l1_human(display_long)|uniprotkb:MAD2L1(gene name)|psi-mi:MAD2L1(display_short)|uniprotkb:MAD2(gene name synonym)|uniprotkb:Mitotic arrest deficient 2-like protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479780|imex:IM-26985-407 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000173120(gene)|ensembl:ENST00000529006(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0032452"(histone demethylase activity)|refseq:NP_036440.1|refseq:XP_011543163.1|refseq:NP_001243334.1|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR032675|mint:Q9Y2K7|rcsb pdb:2YU1|rcsb pdb:2YU2|rcsb pdb:4BBQ|rcsb pdb:6BYH|rcsb pdb:6C16|reactome:R-HSA-3214842|interpro:IPR041070|dip:DIP-34596N ensembl:ENSG00000164109(gene)|ensembl:ENST00000296509(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR036570|mint:Q13257|rcsb pdb:1DUJ|rcsb pdb:1GO4|rcsb pdb:1S2H|rcsb pdb:1KLQ|rcsb pdb:2QYF|rcsb pdb:2V64|rcsb pdb:2VFX|rcsb pdb:3GMH|rcsb pdb:5KHU|rcsb pdb:5LCW|rcsb pdb:6F0X|rcsb pdb:6TLJ|reactome:R-HSA-141405|reactome:R-HSA-141430|reactome:R-HSA-141444|reactome:R-HSA-174184|reactome:R-HSA-176409|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENSP00000296509|ensembl:ENST00000333047|ensembl:ENSP00000332295|refseq:NP_002349.1|dip:DIP-29653N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FWcxfQykne+IrmtpDxZ218sEURc9606 rogid:FyL1tmJllOZ4gQvwWb96aV9PMFw9606 rigid:dH9v945KNOHsg0YevHh7DhGHozU false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y2K7 uniprotkb:P61964 intact:EBI-765758|ensembl:ENSP00000432786|uniprotkb:Q49A21|uniprotkb:Q4G0M3|uniprotkb:Q69YY8|uniprotkb:Q9BVH5|uniprotkb:Q9H7H5|uniprotkb:Q9UK66|uniprotkb:D4QA03|uniprotkb:E9PIL6|uniprotkb:I3VM55 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 psi-mi:kdm2a_human(display_long)|uniprotkb:CXXC8(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1A(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 11(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 11(gene name synonym)|uniprotkb:F-box protein FBL7(gene name synonym)|uniprotkb:F-box protein Lilina(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 8(gene name synonym)|uniprotkb:KDM2A(gene name)|psi-mi:KDM2A(display_short)|uniprotkb:FBL7(gene name synonym)|uniprotkb:KIAA1004(gene name synonym)|uniprotkb:JHDM1A(gene name synonym)|uniprotkb:FBXL11(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1A(gene name synonym)|uniprotkb:FBL11(gene name synonym) psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479780|imex:IM-26985-407 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000173120(gene)|ensembl:ENST00000529006(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0032452"(histone demethylase activity)|refseq:NP_036440.1|refseq:XP_011543163.1|refseq:NP_001243334.1|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR032675|mint:Q9Y2K7|rcsb pdb:2YU1|rcsb pdb:2YU2|rcsb pdb:4BBQ|rcsb pdb:6BYH|rcsb pdb:6C16|reactome:R-HSA-3214842|interpro:IPR041070|dip:DIP-34596N refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FWcxfQykne+IrmtpDxZ218sEURc9606 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rigid:dH9v945KNOHsg0YevHh7DhGHozU false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y2K7 uniprotkb:P62424 intact:EBI-765758|ensembl:ENSP00000432786|uniprotkb:Q49A21|uniprotkb:Q4G0M3|uniprotkb:Q69YY8|uniprotkb:Q9BVH5|uniprotkb:Q9H7H5|uniprotkb:Q9UK66|uniprotkb:D4QA03|uniprotkb:E9PIL6|uniprotkb:I3VM55 intact:EBI-354172|uniprotkb:P11518|uniprotkb:Q5T8U4|ensembl:ENSP00000361076|ensembl:ENSP00000487443 psi-mi:kdm2a_human(display_long)|uniprotkb:CXXC8(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1A(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 11(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 11(gene name synonym)|uniprotkb:F-box protein FBL7(gene name synonym)|uniprotkb:F-box protein Lilina(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 8(gene name synonym)|uniprotkb:KDM2A(gene name)|psi-mi:KDM2A(display_short)|uniprotkb:FBL7(gene name synonym)|uniprotkb:KIAA1004(gene name synonym)|uniprotkb:JHDM1A(gene name synonym)|uniprotkb:FBXL11(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1A(gene name synonym)|uniprotkb:FBL11(gene name synonym) psi-mi:rl7a_human(display_long)|uniprotkb:RPL7A(gene name)|psi-mi:RPL7A(display_short)|uniprotkb:SURF-3(gene name synonym)|uniprotkb:SURF3(gene name synonym)|uniprotkb:Surfeit locus protein 3(gene name synonym)|uniprotkb:PLA-X polypeptide(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479780|imex:IM-26985-407 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000173120(gene)|ensembl:ENST00000529006(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0032452"(histone demethylase activity)|refseq:NP_036440.1|refseq:XP_011543163.1|refseq:NP_001243334.1|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR032675|mint:Q9Y2K7|rcsb pdb:2YU1|rcsb pdb:2YU2|rcsb pdb:4BBQ|rcsb pdb:6BYH|rcsb pdb:6C16|reactome:R-HSA-3214842|interpro:IPR041070|dip:DIP-34596N refseq:NP_000963.1|dip:DIP-31502N|ensembl:ENSG00000148303(gene)|ensembl:ENSG00000280858(gene)|ensembl:ENST00000323345(transcript)|ensembl:ENST00000630979(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR001921(Ribosomal protein L7A)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|mint:P62424|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|go:"GO:0005634"(nucleus)|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FWcxfQykne+IrmtpDxZ218sEURc9606 rogid:shPtLmc+oabT/rSwho+tP1iJy4k9606 rigid:dH9v945KNOHsg0YevHh7DhGHozU false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y2K7 uniprotkb:P05387 intact:EBI-765758|ensembl:ENSP00000432786|uniprotkb:Q49A21|uniprotkb:Q4G0M3|uniprotkb:Q69YY8|uniprotkb:Q9BVH5|uniprotkb:Q9H7H5|uniprotkb:Q9UK66|uniprotkb:D4QA03|uniprotkb:E9PIL6|uniprotkb:I3VM55 intact:EBI-352813|ensembl:ENSP00000322419|ensembl:ENSP00000431240|uniprotkb:Q6FG96 psi-mi:kdm2a_human(display_long)|uniprotkb:CXXC8(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1A(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 11(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 11(gene name synonym)|uniprotkb:F-box protein FBL7(gene name synonym)|uniprotkb:F-box protein Lilina(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 8(gene name synonym)|uniprotkb:KDM2A(gene name)|psi-mi:KDM2A(display_short)|uniprotkb:FBL7(gene name synonym)|uniprotkb:KIAA1004(gene name synonym)|uniprotkb:JHDM1A(gene name synonym)|uniprotkb:FBXL11(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1A(gene name synonym)|uniprotkb:FBL11(gene name synonym) psi-mi:rla2_human(display_long)|uniprotkb:RPLP2(gene name)|psi-mi:RPLP2(display_short)|uniprotkb:RPP2(gene name synonym)|uniprotkb:D11S2243E(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-44(gene name synonym)|uniprotkb:Large ribosomal subunit protein P2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479780|imex:IM-26985-407 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000173120(gene)|ensembl:ENST00000529006(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0032452"(histone demethylase activity)|refseq:NP_036440.1|refseq:XP_011543163.1|refseq:NP_001243334.1|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR032675|mint:Q9Y2K7|rcsb pdb:2YU1|rcsb pdb:2YU2|rcsb pdb:4BBQ|rcsb pdb:6BYH|rcsb pdb:6C16|reactome:R-HSA-3214842|interpro:IPR041070|dip:DIP-34596N ensembl:ENSG00000177600(gene)|ensembl:ENST00000321153(transcript)|ensembl:ENST00000530797(transcript)|go:"GO:0002182"(cytoplasmic translational elongation)|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-72689|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR027534|interpro:IPR038716|interpro:IPR044076|mint:P05387|rcsb pdb:1S4J|rcsb pdb:2JDL|rcsb pdb:2LBF|rcsb pdb:2W1O|rcsb pdb:4BEH|rcsb pdb:4V6X|rcsb pdb:5DDZ|rcsb pdb:5GU4|go:"GO:0003735"(structural constituent of ribosome)|reactome:R-HSA-156827|reactome:R-HSA-156902|refseq:NP_000995.1 - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FWcxfQykne+IrmtpDxZ218sEURc9606 rogid:IBI+x82JJYg66MPhGKw1/pI/bQA9606 rigid:dH9v945KNOHsg0YevHh7DhGHozU false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y2K7 uniprotkb:Q15291 intact:EBI-765758|ensembl:ENSP00000432786|uniprotkb:Q49A21|uniprotkb:Q4G0M3|uniprotkb:Q69YY8|uniprotkb:Q9BVH5|uniprotkb:Q9H7H5|uniprotkb:Q9UK66|uniprotkb:D4QA03|uniprotkb:E9PIL6|uniprotkb:I3VM55 intact:EBI-592823|uniprotkb:A8K272|uniprotkb:Q7Z6D8|uniprotkb:Q8NDZ7|ensembl:ENSP00000264515 psi-mi:kdm2a_human(display_long)|uniprotkb:CXXC8(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1A(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 11(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 11(gene name synonym)|uniprotkb:F-box protein FBL7(gene name synonym)|uniprotkb:F-box protein Lilina(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 8(gene name synonym)|uniprotkb:KDM2A(gene name)|psi-mi:KDM2A(display_short)|uniprotkb:FBL7(gene name synonym)|uniprotkb:KIAA1004(gene name synonym)|uniprotkb:JHDM1A(gene name synonym)|uniprotkb:FBXL11(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1A(gene name synonym)|uniprotkb:FBL11(gene name synonym) psi-mi:rbbp5_human(display_long)|uniprotkb:Retinoblastoma-binding protein RBQ-3(gene name synonym)|uniprotkb:RBBP5(gene name)|psi-mi:RBBP5(display_short)|uniprotkb:RBQ3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479780|imex:IM-26985-407 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000173120(gene)|ensembl:ENST00000529006(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0032452"(histone demethylase activity)|refseq:NP_036440.1|refseq:XP_011543163.1|refseq:NP_001243334.1|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR032675|mint:Q9Y2K7|rcsb pdb:2YU1|rcsb pdb:2YU2|rcsb pdb:4BBQ|rcsb pdb:6BYH|rcsb pdb:6C16|reactome:R-HSA-3214842|interpro:IPR041070|dip:DIP-34596N refseq:NP_001180201.1|refseq:NP_001180202.1|refseq:NP_005048.2|dip:DIP-29224N|ensembl:ENSG00000117222(gene)|ensembl:ENST00000264515(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037850|mint:Q15291|rcsb pdb:3P4F|rcsb pdb:4X8N|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6KM7|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6PWX|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664 - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FWcxfQykne+IrmtpDxZ218sEURc9606 rogid:Zl8yHcbL1C6StHPyD+875Ccy6gk9606 rigid:dH9v945KNOHsg0YevHh7DhGHozU false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y2K7 uniprotkb:Q9UBL3 intact:EBI-765758|ensembl:ENSP00000432786|uniprotkb:Q49A21|uniprotkb:Q4G0M3|uniprotkb:Q69YY8|uniprotkb:Q9BVH5|uniprotkb:Q9H7H5|uniprotkb:Q9UK66|uniprotkb:D4QA03|uniprotkb:E9PIL6|uniprotkb:I3VM55 intact:EBI-540797|uniprotkb:O60659|uniprotkb:O60660|uniprotkb:Q96B62|ensembl:ENSP00000340896|uniprotkb:A8K7C3|uniprotkb:D3DSW9 psi-mi:kdm2a_human(display_long)|uniprotkb:CXXC8(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1A(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 11(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 11(gene name synonym)|uniprotkb:F-box protein FBL7(gene name synonym)|uniprotkb:F-box protein Lilina(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 8(gene name synonym)|uniprotkb:KDM2A(gene name)|psi-mi:KDM2A(display_short)|uniprotkb:FBL7(gene name synonym)|uniprotkb:KIAA1004(gene name synonym)|uniprotkb:JHDM1A(gene name synonym)|uniprotkb:FBXL11(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1A(gene name synonym)|uniprotkb:FBL11(gene name synonym) psi-mi:ash2l_human(display_long)|uniprotkb:ASH2-like protein(gene name synonym)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479780|imex:IM-26985-407 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000173120(gene)|ensembl:ENST00000529006(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0032452"(histone demethylase activity)|refseq:NP_036440.1|refseq:XP_011543163.1|refseq:NP_001243334.1|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR032675|mint:Q9Y2K7|rcsb pdb:2YU1|rcsb pdb:2YU2|rcsb pdb:4BBQ|rcsb pdb:6BYH|rcsb pdb:6C16|reactome:R-HSA-3214842|interpro:IPR041070|dip:DIP-34596N refseq:NP_001098684.1|refseq:NP_004665.2|ensembl:ENSG00000129691(gene)|ensembl:ENST00000343823(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|mint:Q9UBL3|rcsb pdb:3RSN|rcsb pdb:3S32|rcsb pdb:3TOJ|rcsb pdb:4RIQ|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6E2H|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|rcsb pdb:4X8N|refseq:NP_001248761.1|dip:DIP-29222N - - comment:"author score: 32" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FWcxfQykne+IrmtpDxZ218sEURc9606 rogid:ZUYI3M78nGeeb8K2eIiDSw1uWeo9606 rigid:dH9v945KNOHsg0YevHh7DhGHozU false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y2K7 uniprotkb:P16403 intact:EBI-765758|ensembl:ENSP00000432786|uniprotkb:Q49A21|uniprotkb:Q4G0M3|uniprotkb:Q69YY8|uniprotkb:Q9BVH5|uniprotkb:Q9H7H5|uniprotkb:Q9UK66|uniprotkb:D4QA03|uniprotkb:E9PIL6|uniprotkb:I3VM55 intact:EBI-358372|ensembl:ENSP00000339566|uniprotkb:A8K4I2 psi-mi:kdm2a_human(display_long)|uniprotkb:CXXC8(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1A(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 11(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 11(gene name synonym)|uniprotkb:F-box protein FBL7(gene name synonym)|uniprotkb:F-box protein Lilina(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 8(gene name synonym)|uniprotkb:KDM2A(gene name)|psi-mi:KDM2A(display_short)|uniprotkb:FBL7(gene name synonym)|uniprotkb:KIAA1004(gene name synonym)|uniprotkb:JHDM1A(gene name synonym)|uniprotkb:FBXL11(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1A(gene name synonym)|uniprotkb:FBL11(gene name synonym) psi-mi:h12_human(display_long)|uniprotkb:H1-2(gene name)|psi-mi:H1-2(display_short)|uniprotkb:H1F2(gene name synonym)|uniprotkb:HIST1H1C(gene name synonym)|uniprotkb:Histone H1c(gene name synonym)|uniprotkb:Histone H1d(gene name synonym)|uniprotkb:Histone H1s-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479780|imex:IM-26985-407 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000173120(gene)|ensembl:ENST00000529006(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0032452"(histone demethylase activity)|refseq:NP_036440.1|refseq:XP_011543163.1|refseq:NP_001243334.1|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR032675|mint:Q9Y2K7|rcsb pdb:2YU1|rcsb pdb:2YU2|rcsb pdb:4BBQ|rcsb pdb:6BYH|rcsb pdb:6C16|reactome:R-HSA-3214842|interpro:IPR041070|dip:DIP-34596N refseq:NP_005310.1|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P16403|reactome:R-HSA-140342|reactome:R-HSA-2559584|ensembl:ENSG00000187837(gene)|ensembl:ENST00000343677(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|dip:DIP-36359N - - comment:"author score: 32" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FWcxfQykne+IrmtpDxZ218sEURc9606 rogid:eRT5bTyBJUg6nRANMRYZekT4N+g9606 rigid:dH9v945KNOHsg0YevHh7DhGHozU false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y2K7 uniprotkb:Q96P16 intact:EBI-765758|ensembl:ENSP00000432786|uniprotkb:Q49A21|uniprotkb:Q4G0M3|uniprotkb:Q69YY8|uniprotkb:Q9BVH5|uniprotkb:Q9H7H5|uniprotkb:Q9UK66|uniprotkb:D4QA03|uniprotkb:E9PIL6|uniprotkb:I3VM55 intact:EBI-1053506|uniprotkb:Q7Z5G8|uniprotkb:Q96FY9|uniprotkb:Q9NVL4|uniprotkb:A8KA42|uniprotkb:B2RBA3|ensembl:ENSP00000349955|ensembl:ENSP00000381984 psi-mi:kdm2a_human(display_long)|uniprotkb:CXXC8(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1A(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 11(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 11(gene name synonym)|uniprotkb:F-box protein FBL7(gene name synonym)|uniprotkb:F-box protein Lilina(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 8(gene name synonym)|uniprotkb:KDM2A(gene name)|psi-mi:KDM2A(display_short)|uniprotkb:FBL7(gene name synonym)|uniprotkb:KIAA1004(gene name synonym)|uniprotkb:JHDM1A(gene name synonym)|uniprotkb:FBXL11(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1A(gene name synonym)|uniprotkb:FBL11(gene name synonym) psi-mi:rpr1a_human(display_long)|uniprotkb:RPRD1A(gene name)|psi-mi:RPRD1A(display_short)|uniprotkb:p15INK4B-related protein(gene name synonym)|uniprotkb:P15RS(gene name synonym)|uniprotkb:Cyclin-dependent kinase inhibitor 2B-related protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479780|imex:IM-26985-407 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000173120(gene)|ensembl:ENST00000529006(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0032452"(histone demethylase activity)|refseq:NP_036440.1|refseq:XP_011543163.1|refseq:NP_001243334.1|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR032675|mint:Q9Y2K7|rcsb pdb:2YU1|rcsb pdb:2YU2|rcsb pdb:4BBQ|rcsb pdb:6BYH|rcsb pdb:6C16|reactome:R-HSA-3214842|interpro:IPR041070|dip:DIP-34596N refseq:XP_011524350.1|refseq:XP_011524351.1|refseq:XP_011524352.1|refseq:NP_060640.2|refseq:NP_001290340.1|refseq:NP_001290341.1|refseq:NP_001290342.1|ensembl:ENSG00000141425(gene)|ensembl:ENST00000357384(transcript)|ensembl:ENST00000399022(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q96P16|rcsb pdb:4JXT|rcsb pdb:4NAC|reactome:R-HSA-6807505|dip:DIP-50901N - - comment:"author score: 42" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FWcxfQykne+IrmtpDxZ218sEURc9606 rogid:RGCJx8nL9gil6DmtiiFboxeNUSU9606 rigid:dH9v945KNOHsg0YevHh7DhGHozU false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y2K7 uniprotkb:Q9C005 intact:EBI-765758|ensembl:ENSP00000432786|uniprotkb:Q49A21|uniprotkb:Q4G0M3|uniprotkb:Q69YY8|uniprotkb:Q9BVH5|uniprotkb:Q9H7H5|uniprotkb:Q9UK66|uniprotkb:D4QA03|uniprotkb:E9PIL6|uniprotkb:I3VM55 intact:EBI-744973|uniprotkb:D6W578|ensembl:ENSP00000295066|ensembl:ENSP00000345837 psi-mi:kdm2a_human(display_long)|uniprotkb:CXXC8(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1A(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 11(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 11(gene name synonym)|uniprotkb:F-box protein FBL7(gene name synonym)|uniprotkb:F-box protein Lilina(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 8(gene name synonym)|uniprotkb:KDM2A(gene name)|psi-mi:KDM2A(display_short)|uniprotkb:FBL7(gene name synonym)|uniprotkb:KIAA1004(gene name synonym)|uniprotkb:JHDM1A(gene name synonym)|uniprotkb:FBXL11(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1A(gene name synonym)|uniprotkb:FBL11(gene name synonym) psi-mi:dpy30_human(display_long)|uniprotkb:DPY30(gene name)|psi-mi:DPY30(display_short)|uniprotkb:Dpy-30-like protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479780|imex:IM-26985-407 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000173120(gene)|ensembl:ENST00000529006(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0032452"(histone demethylase activity)|refseq:NP_036440.1|refseq:XP_011543163.1|refseq:NP_001243334.1|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR032675|mint:Q9Y2K7|rcsb pdb:2YU1|rcsb pdb:2YU2|rcsb pdb:4BBQ|rcsb pdb:6BYH|rcsb pdb:6C16|reactome:R-HSA-3214842|interpro:IPR041070|dip:DIP-34596N refseq:NP_115963.1|ensembl:ENSG00000162961(gene)|ensembl:ENST00000295066(transcript)|ensembl:ENST00000342166(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006348"|go:"GO:0016197"(endosomal transport)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|mint:Q9C005|rcsb pdb:3G36|rcsb pdb:4RIQ|rcsb pdb:4RT4|rcsb pdb:4RTA|rcsb pdb:6E2H|rcsb pdb:6PWV|reactome:R-HSA-3214841|reactome:R-HSA-8936459|refseq:NP_001308138.1|dip:DIP-34476N - - comment:"author score: 44" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FWcxfQykne+IrmtpDxZ218sEURc9606 rogid:yC9NJhTfEIT+YyfWRSJLGbRsQkc9606 rigid:dH9v945KNOHsg0YevHh7DhGHozU false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y2K7 uniprotkb:P63208 intact:EBI-765758|ensembl:ENSP00000432786|uniprotkb:Q49A21|uniprotkb:Q4G0M3|uniprotkb:Q69YY8|uniprotkb:Q9BVH5|uniprotkb:Q9H7H5|uniprotkb:Q9UK66|uniprotkb:D4QA03|uniprotkb:E9PIL6|uniprotkb:I3VM55 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 psi-mi:kdm2a_human(display_long)|uniprotkb:CXXC8(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1A(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 11(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 11(gene name synonym)|uniprotkb:F-box protein FBL7(gene name synonym)|uniprotkb:F-box protein Lilina(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 8(gene name synonym)|uniprotkb:KDM2A(gene name)|psi-mi:KDM2A(display_short)|uniprotkb:FBL7(gene name synonym)|uniprotkb:KIAA1004(gene name synonym)|uniprotkb:JHDM1A(gene name synonym)|uniprotkb:FBXL11(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1A(gene name synonym)|uniprotkb:FBL11(gene name synonym) psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479780|imex:IM-26985-407 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000173120(gene)|ensembl:ENST00000529006(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0032452"(histone demethylase activity)|refseq:NP_036440.1|refseq:XP_011543163.1|refseq:NP_001243334.1|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR032675|mint:Q9Y2K7|rcsb pdb:2YU1|rcsb pdb:2YU2|rcsb pdb:4BBQ|rcsb pdb:6BYH|rcsb pdb:6C16|reactome:R-HSA-3214842|interpro:IPR041070|dip:DIP-34596N reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N - - comment:"author score: 77" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FWcxfQykne+IrmtpDxZ218sEURc9606 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rigid:dH9v945KNOHsg0YevHh7DhGHozU false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHM5 uniprotkb:P16104 intact:EBI-3955564|uniprotkb:Q1RLM7|uniprotkb:Q8NCI2|uniprotkb:Q96HC7|uniprotkb:Q96SL0|uniprotkb:Q96T03|uniprotkb:Q9NS96|uniprotkb:Q9UF75|ensembl:ENSP00000366271|uniprotkb:A8MRS1 intact:EBI-494830|uniprotkb:Q4ZGJ7|uniprotkb:Q6IAS5|ensembl:ENSP00000364310|ensembl:ENSP00000434024 psi-mi:kdm2b_human(display_long)|uniprotkb:KDM2B(gene name)|psi-mi:KDM2B(display_short)|uniprotkb:CXXC2(gene name synonym)|uniprotkb:FBL10(gene name synonym)|uniprotkb:FBXL10(gene name synonym)|uniprotkb:JHDM1B(gene name synonym)|uniprotkb:PCCX2(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 2(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 10(gene name synonym)|uniprotkb:F-box protein FBL10(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 10(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1B(gene name synonym)|uniprotkb:Jumonji domain-containing EMSY-interactor methyltransferase motif protein(gene name synonym)|uniprotkb:Protein-containing CXXC domain 2(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1B(gene name synonym)|uniprotkb:NDY1(gene name synonym) psi-mi:h2ax_human(display_long)|uniprotkb:H2AX(gene name)|psi-mi:H2AX(display_short)|uniprotkb:H2AFX(gene name synonym)|uniprotkb:Histone H2A.X(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479825|imex:IM-26985-479 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENST00000377071(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0021555"(midbrain-hindbrain boundary morphogenesis)|go:"GO:0021592"(fourth ventricle development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021678"(third ventricle development)|go:"GO:0021993"(initiation of neural tube closure)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|interpro:IPR041070|interpro:IPR041667|mint:Q8NHM5|rcsb pdb:4O64|rcsb pdb:5JH5|rcsb pdb:6BVA|reactome:R-HSA-3214842|refseq:NP_115979.3|ensembl:ENSG00000089094(gene)|refseq:NP_001005366.1 ensembl:ENSG00000188486(gene)|ensembl:ENST00000375167(transcript)|ensembl:ENST00000530167(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000786"(nucleosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|refseq:NP_002096.1|dip:DIP-33604N|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|go:"GO:0005813"(centrosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090398"(cellular senescence)|go:"GO:0090734"(site of DNA damage)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P16104|rcsb pdb:1YDP|rcsb pdb:2AZM|rcsb pdb:2D31|rcsb pdb:2DYP|rcsb pdb:3SHV|rcsb pdb:3SQD|rcsb pdb:3SZM|rcsb pdb:3U3Z|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K - - comment:"author score: 31" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:tnMbfP2oxwaaDyHHAigNt5hx4hM9606 rogid:VQoEp3F8lEBTOj+PDDUzrJCQNZA9606 rigid:93vraGIiMudeHKPZzjV4tG/6JYQ false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHM5 uniprotkb:Q71DI3 intact:EBI-3955564|uniprotkb:Q1RLM7|uniprotkb:Q8NCI2|uniprotkb:Q96HC7|uniprotkb:Q96SL0|uniprotkb:Q96T03|uniprotkb:Q9NS96|uniprotkb:Q9UF75|ensembl:ENSP00000366271|uniprotkb:A8MRS1 intact:EBI-750650|uniprotkb:A2BDF6|uniprotkb:A6NFS4|uniprotkb:Q6B053|ensembl:ENSP00000333277|ensembl:ENSP00000358154|ensembl:ENSP00000385479 psi-mi:kdm2b_human(display_long)|uniprotkb:KDM2B(gene name)|psi-mi:KDM2B(display_short)|uniprotkb:CXXC2(gene name synonym)|uniprotkb:FBL10(gene name synonym)|uniprotkb:FBXL10(gene name synonym)|uniprotkb:JHDM1B(gene name synonym)|uniprotkb:PCCX2(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 2(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 10(gene name synonym)|uniprotkb:F-box protein FBL10(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 10(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1B(gene name synonym)|uniprotkb:Jumonji domain-containing EMSY-interactor methyltransferase motif protein(gene name synonym)|uniprotkb:Protein-containing CXXC domain 2(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1B(gene name synonym)|uniprotkb:NDY1(gene name synonym) psi-mi:h32_human(display_long)|uniprotkb:H3C13(gene name)|psi-mi:H3C13(display_short)|uniprotkb:H3C14(gene name)|psi-mi:H3C14(display_short)|uniprotkb:H3C15(gene name)|psi-mi:H3C15(display_short)|uniprotkb:H3-clustered histone 13(gene name synonym)|uniprotkb:H3-clustered histone 14(gene name synonym)|uniprotkb:H3-clustered histone 15(gene name synonym)|uniprotkb:H3F2(gene name synonym)|uniprotkb:H3FM(gene name synonym)|uniprotkb:HIST2H3A(gene name synonym)|uniprotkb:HIST2H3C(gene name synonym)|uniprotkb:HIST2H3D(gene name synonym)|uniprotkb:Histone H3/m(gene name synonym)|uniprotkb:Histone H3/o(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479825|imex:IM-26985-479 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENST00000377071(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0021555"(midbrain-hindbrain boundary morphogenesis)|go:"GO:0021592"(fourth ventricle development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021678"(third ventricle development)|go:"GO:0021993"(initiation of neural tube closure)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|interpro:IPR041070|interpro:IPR041667|mint:Q8NHM5|rcsb pdb:4O64|rcsb pdb:5JH5|rcsb pdb:6BVA|reactome:R-HSA-3214842|refseq:NP_115979.3|ensembl:ENSG00000089094(gene)|refseq:NP_001005366.1 refseq:NP_001005464.1|refseq:NP_001116847.1|refseq:NP_066403.2|dip:DIP-48606N|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|rcsb pdb:7BU9|rcsb pdb:7JO9|rcsb pdb:7JOA|reactome:R-HSA-3214858|reactome:R-HSA-3247509|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-983231|rcsb pdb:7JZV|reactome:R-HSA-1266695|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|ensembl:ENSG00000183598(gene)|ensembl:ENSG00000203811(gene)|ensembl:ENSG00000203852(gene)|ensembl:ENST00000331491(transcript)|ensembl:ENST00000369158(transcript)|ensembl:ENST00000403683(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:Q71DI3|rcsb pdb:2IIJ|rcsb pdb:2X4W|rcsb pdb:2X4X|rcsb pdb:2X4Y|rcsb pdb:3AV1|rcsb pdb:3DB3|rcsb pdb:3MO8|rcsb pdb:3QO2|rcsb pdb:3R93|rcsb pdb:4MZF|rcsb pdb:4MZG|rcsb pdb:4MZH|rcsb pdb:4OUC|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B40|rcsb pdb:5BO0|rcsb pdb:5CIU|rcsb pdb:5VAC|rcsb pdb:6ACE|rcsb pdb:6FML|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6Y5E|rcsb pdb:7BQZ - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:tnMbfP2oxwaaDyHHAigNt5hx4hM9606 rogid:2TuVqWkeAnhHR4nrl0GNyUj1N3o9606 rigid:93vraGIiMudeHKPZzjV4tG/6JYQ false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHM5 uniprotkb:Q99496 intact:EBI-3955564|uniprotkb:Q1RLM7|uniprotkb:Q8NCI2|uniprotkb:Q96HC7|uniprotkb:Q96SL0|uniprotkb:Q96T03|uniprotkb:Q9NS96|uniprotkb:Q9UF75|ensembl:ENSP00000366271|uniprotkb:A8MRS1 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:kdm2b_human(display_long)|uniprotkb:KDM2B(gene name)|psi-mi:KDM2B(display_short)|uniprotkb:CXXC2(gene name synonym)|uniprotkb:FBL10(gene name synonym)|uniprotkb:FBXL10(gene name synonym)|uniprotkb:JHDM1B(gene name synonym)|uniprotkb:PCCX2(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 2(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 10(gene name synonym)|uniprotkb:F-box protein FBL10(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 10(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1B(gene name synonym)|uniprotkb:Jumonji domain-containing EMSY-interactor methyltransferase motif protein(gene name synonym)|uniprotkb:Protein-containing CXXC domain 2(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1B(gene name synonym)|uniprotkb:NDY1(gene name synonym) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479825|imex:IM-26985-479 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENST00000377071(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0021555"(midbrain-hindbrain boundary morphogenesis)|go:"GO:0021592"(fourth ventricle development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021678"(third ventricle development)|go:"GO:0021993"(initiation of neural tube closure)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|interpro:IPR041070|interpro:IPR041667|mint:Q8NHM5|rcsb pdb:4O64|rcsb pdb:5JH5|rcsb pdb:6BVA|reactome:R-HSA-3214842|refseq:NP_115979.3|ensembl:ENSG00000089094(gene)|refseq:NP_001005366.1 refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 - - comment:"author score: 31" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:tnMbfP2oxwaaDyHHAigNt5hx4hM9606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rigid:93vraGIiMudeHKPZzjV4tG/6JYQ false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHM5 uniprotkb:Q5H9F3 intact:EBI-3955564|uniprotkb:Q1RLM7|uniprotkb:Q8NCI2|uniprotkb:Q96HC7|uniprotkb:Q96SL0|uniprotkb:Q96T03|uniprotkb:Q9NS96|uniprotkb:Q9UF75|ensembl:ENSP00000366271|uniprotkb:A8MRS1 intact:EBI-8833946|uniprotkb:Q5H9F4|uniprotkb:Q9Y528|uniprotkb:Q8TEN3|uniprotkb:B5MDQ8|uniprotkb:Q6ZVE0|uniprotkb:Q5H9F2|ensembl:ENSP00000218147|ensembl:ENSP00000437775 psi-mi:kdm2b_human(display_long)|uniprotkb:KDM2B(gene name)|psi-mi:KDM2B(display_short)|uniprotkb:CXXC2(gene name synonym)|uniprotkb:FBL10(gene name synonym)|uniprotkb:FBXL10(gene name synonym)|uniprotkb:JHDM1B(gene name synonym)|uniprotkb:PCCX2(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 2(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 10(gene name synonym)|uniprotkb:F-box protein FBL10(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 10(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1B(gene name synonym)|uniprotkb:Jumonji domain-containing EMSY-interactor methyltransferase motif protein(gene name synonym)|uniprotkb:Protein-containing CXXC domain 2(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1B(gene name synonym)|uniprotkb:NDY1(gene name synonym) psi-mi:bcorl_human(display_long)|uniprotkb:BCORL1(gene name)|psi-mi:BCORL1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479825|imex:IM-26985-479 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENST00000377071(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0021555"(midbrain-hindbrain boundary morphogenesis)|go:"GO:0021592"(fourth ventricle development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021678"(third ventricle development)|go:"GO:0021993"(initiation of neural tube closure)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|interpro:IPR041070|interpro:IPR041667|mint:Q8NHM5|rcsb pdb:4O64|rcsb pdb:5JH5|rcsb pdb:6BVA|reactome:R-HSA-3214842|refseq:NP_115979.3|ensembl:ENSG00000089094(gene)|refseq:NP_001005366.1 ensembl:ENSP00000218147|ensembl:ENSP00000437775|refseq:NP_068765.3|dip:DIP-60148N|ensembl:ENSG00000085185(gene)|ensembl:ENST00000218147(transcript)|ensembl:ENST00000540052(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q5H9F3|rcsb pdb:4HPM|rcsb pdb:5JH5 - - comment:"author score: 37" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:tnMbfP2oxwaaDyHHAigNt5hx4hM9606 rogid:uQdpjjO3QnnX19nR1Ky76HjCdhw9606 rigid:93vraGIiMudeHKPZzjV4tG/6JYQ false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHM5 uniprotkb:Q9BSM1 intact:EBI-3955564|uniprotkb:Q1RLM7|uniprotkb:Q8NCI2|uniprotkb:Q96HC7|uniprotkb:Q96SL0|uniprotkb:Q96T03|uniprotkb:Q9NS96|uniprotkb:Q9UF75|ensembl:ENSP00000366271|uniprotkb:A8MRS1 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 psi-mi:kdm2b_human(display_long)|uniprotkb:KDM2B(gene name)|psi-mi:KDM2B(display_short)|uniprotkb:CXXC2(gene name synonym)|uniprotkb:FBL10(gene name synonym)|uniprotkb:FBXL10(gene name synonym)|uniprotkb:JHDM1B(gene name synonym)|uniprotkb:PCCX2(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 2(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 10(gene name synonym)|uniprotkb:F-box protein FBL10(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 10(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1B(gene name synonym)|uniprotkb:Jumonji domain-containing EMSY-interactor methyltransferase motif protein(gene name synonym)|uniprotkb:Protein-containing CXXC domain 2(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1B(gene name synonym)|uniprotkb:NDY1(gene name synonym) psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479825|imex:IM-26985-479 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENST00000377071(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0021555"(midbrain-hindbrain boundary morphogenesis)|go:"GO:0021592"(fourth ventricle development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021678"(third ventricle development)|go:"GO:0021993"(initiation of neural tube closure)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|interpro:IPR041070|interpro:IPR041667|mint:Q8NHM5|rcsb pdb:4O64|rcsb pdb:5JH5|rcsb pdb:6BVA|reactome:R-HSA-3214842|refseq:NP_115979.3|ensembl:ENSG00000089094(gene)|refseq:NP_001005366.1 refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 - - comment:"author score: 62" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:tnMbfP2oxwaaDyHHAigNt5hx4hM9606 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rigid:93vraGIiMudeHKPZzjV4tG/6JYQ false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHM5 uniprotkb:Q6W2J9 intact:EBI-3955564|uniprotkb:Q1RLM7|uniprotkb:Q8NCI2|uniprotkb:Q96HC7|uniprotkb:Q96SL0|uniprotkb:Q96T03|uniprotkb:Q9NS96|uniprotkb:Q9UF75|ensembl:ENSP00000366271|uniprotkb:A8MRS1 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 psi-mi:kdm2b_human(display_long)|uniprotkb:KDM2B(gene name)|psi-mi:KDM2B(display_short)|uniprotkb:CXXC2(gene name synonym)|uniprotkb:FBL10(gene name synonym)|uniprotkb:FBXL10(gene name synonym)|uniprotkb:JHDM1B(gene name synonym)|uniprotkb:PCCX2(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 2(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 10(gene name synonym)|uniprotkb:F-box protein FBL10(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 10(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1B(gene name synonym)|uniprotkb:Jumonji domain-containing EMSY-interactor methyltransferase motif protein(gene name synonym)|uniprotkb:Protein-containing CXXC domain 2(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1B(gene name synonym)|uniprotkb:NDY1(gene name synonym) psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479825|imex:IM-26985-479 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENST00000377071(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0021555"(midbrain-hindbrain boundary morphogenesis)|go:"GO:0021592"(fourth ventricle development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021678"(third ventricle development)|go:"GO:0021993"(initiation of neural tube closure)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|interpro:IPR041070|interpro:IPR041667|mint:Q8NHM5|rcsb pdb:4O64|rcsb pdb:5JH5|rcsb pdb:6BVA|reactome:R-HSA-3214842|refseq:NP_115979.3|ensembl:ENSG00000089094(gene)|refseq:NP_001005366.1 ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N - - comment:"author score: 73" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:tnMbfP2oxwaaDyHHAigNt5hx4hM9606 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rigid:93vraGIiMudeHKPZzjV4tG/6JYQ false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHM5 uniprotkb:P63208 intact:EBI-3955564|uniprotkb:Q1RLM7|uniprotkb:Q8NCI2|uniprotkb:Q96HC7|uniprotkb:Q96SL0|uniprotkb:Q96T03|uniprotkb:Q9NS96|uniprotkb:Q9UF75|ensembl:ENSP00000366271|uniprotkb:A8MRS1 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 psi-mi:kdm2b_human(display_long)|uniprotkb:KDM2B(gene name)|psi-mi:KDM2B(display_short)|uniprotkb:CXXC2(gene name synonym)|uniprotkb:FBL10(gene name synonym)|uniprotkb:FBXL10(gene name synonym)|uniprotkb:JHDM1B(gene name synonym)|uniprotkb:PCCX2(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 2(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 10(gene name synonym)|uniprotkb:F-box protein FBL10(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 10(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1B(gene name synonym)|uniprotkb:Jumonji domain-containing EMSY-interactor methyltransferase motif protein(gene name synonym)|uniprotkb:Protein-containing CXXC domain 2(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1B(gene name synonym)|uniprotkb:NDY1(gene name synonym) psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479825|imex:IM-26985-479 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENST00000377071(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0021555"(midbrain-hindbrain boundary morphogenesis)|go:"GO:0021592"(fourth ventricle development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021678"(third ventricle development)|go:"GO:0021993"(initiation of neural tube closure)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|interpro:IPR041070|interpro:IPR041667|mint:Q8NHM5|rcsb pdb:4O64|rcsb pdb:5JH5|rcsb pdb:6BVA|reactome:R-HSA-3214842|refseq:NP_115979.3|ensembl:ENSG00000089094(gene)|refseq:NP_001005366.1 reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N - - comment:"author score: 90" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:tnMbfP2oxwaaDyHHAigNt5hx4hM9606 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rigid:93vraGIiMudeHKPZzjV4tG/6JYQ false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99417 uniprotkb:Q9Y4C1 intact:EBI-716185|intact:EBI-2559925|uniprotkb:Q5TA64|uniprotkb:Q96HE2|uniprotkb:B2R4N0|ensembl:ENSP00000380702 intact:EBI-2515339|ensembl:ENSP00000323659|ensembl:ENSP00000386516|ensembl:ENSP00000386660|uniprotkb:Q68UT9|uniprotkb:Q8IY08|uniprotkb:Q68D47|uniprotkb:Q53S72|uniprotkb:Q6N050|uniprotkb:D6W5M3 psi-mi:mycbp_human(display_long)|uniprotkb:Associate of Myc 1(gene name synonym)|uniprotkb:MYCBP(gene name)|psi-mi:MYCBP(display_short)|uniprotkb:AMY1(gene name synonym) psi-mi:kdm3a_human(display_long)|uniprotkb:KDM3A(gene name)|psi-mi:KDM3A(display_short)|uniprotkb:JHDM2A(gene name synonym)|uniprotkb:JMJD1(gene name synonym)|uniprotkb:JMJD1A(gene name synonym)|uniprotkb:KIAA0742(gene name synonym)|uniprotkb:TSGA(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 2A(gene name synonym)|uniprotkb:Jumonji domain-containing protein 1A(gene name synonym)|uniprotkb:"[histone H3]-dimethyl-L-lysine(9) demethylase 3A"(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25479852|imex:IM-26985-25 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036465.2|ensembl:ENSG00000214114(gene)|ensembl:ENST00000397572(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007283"(spermatogenesis)|interpro:IPR026060|mint:Q99417|rcsb pdb:2YY0 ensembl:ENSG00000115548(gene)|ensembl:ENST00000312912(transcript)|ensembl:ENST00000409064(transcript)|ensembl:ENST00000409556(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0000785"(chromatin)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007290"(spermatid nucleus elongation)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046293"(formaldehyde biosynthetic process)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000036"(regulation of stem cell population maintenance)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q9Y4C1|reactome:R-HSA-3214842|reactome:R-HSA-9029569|refseq:NP_001140160.1|refseq:NP_060903.2|refseq:XP_016859982.1|dip:DIP-53661N - comment:"author score: 12" - figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:jIStn1A10DDkgTuwVeKpDPJ6tIs9606 rogid:XF6xqiiGohV0b2e/bzVx+J0XH7I9606 rigid:WrQdKNnEZC2SkZWGNfgrAlI9GeY false - tandem tag:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7LBC6 uniprotkb:P50213 intact:EBI-2511832|ensembl:ENSP00000326563|uniprotkb:Q9BW93|uniprotkb:Q9BZ52|uniprotkb:Q9BVH6|uniprotkb:A6H8X7|uniprotkb:Q9UPS0|uniprotkb:Q9NYF4 intact:EBI-355999|uniprotkb:D3DW83|uniprotkb:Q9H3X0|ensembl:ENSP00000299518 psi-mi:kdm3b_human(display_long)|uniprotkb:KDM3B(gene name)|psi-mi:KDM3B(display_short)|uniprotkb:C5orf7(gene name synonym)|uniprotkb:JHDM2B(gene name synonym)|uniprotkb:JMJD1B(gene name synonym)|uniprotkb:KIAA1082(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 2B(gene name synonym)|uniprotkb:Jumonji domain-containing protein 1B(gene name synonym)|uniprotkb:Nuclear protein 5qNCA(gene name synonym)|uniprotkb:"[histone H3]-dimethyl-L-lysine(9) demethylase 3B"(gene name synonym) psi-mi:idh3a_human(display_long)|uniprotkb:IDH3A(gene name)|psi-mi:IDH3A(display_short)|uniprotkb:Isocitric dehydrogenase subunit alpha(gene name synonym)|uniprotkb:"NAD(+)-specific ICDH subunit alpha"(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479861|imex:IM-26985-173 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120733(gene)|ensembl:ENST00000314358(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016209"(antioxidant activity)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0072718"(response to cisplatin)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q7LBC6|rcsb pdb:4C8D|rcsb pdb:5R7X|rcsb pdb:5RAA|rcsb pdb:5RAC|rcsb pdb:5RAD|rcsb pdb:5RAE|rcsb pdb:5RAF|rcsb pdb:5RAG|rcsb pdb:5RAH|rcsb pdb:5RAI|rcsb pdb:5RAJ|rcsb pdb:5RAK|rcsb pdb:5RAL|rcsb pdb:5RAM|rcsb pdb:5RAN|rcsb pdb:5RAO|rcsb pdb:5RAP|rcsb pdb:5RAQ|rcsb pdb:5RAR|rcsb pdb:5RAS|rcsb pdb:5RAB|rcsb pdb:5RAU|rcsb pdb:5RAV|rcsb pdb:5RAW|rcsb pdb:5RAX|rcsb pdb:5RAY|rcsb pdb:5RAZ|rcsb pdb:5RB0|rcsb pdb:5RB1|rcsb pdb:5RB2|rcsb pdb:5RB3|rcsb pdb:5RB4|rcsb pdb:5RB5|rcsb pdb:5RB6|rcsb pdb:5RB7|rcsb pdb:6RBJ|reactome:R-HSA-3214842|refseq:NP_057688.2 refseq:NP_005521.1|interpro:IPR024084|ensembl:ENSG00000166411(gene)|ensembl:ENST00000299518(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004449"("isocitrate dehydrogenase (NAD+) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0051287"(NAD binding)|interpro:IPR004434(Isocitrate dehydrogenase NAD-dependent, mitochondrial)|interpro:IPR019818|mint:P50213|rcsb pdb:5GRE|rcsb pdb:5GRF|rcsb pdb:5GRH|rcsb pdb:5GRI|rcsb pdb:5GRL|rcsb pdb:5YVT|rcsb pdb:6KDE|rcsb pdb:6KDF|rcsb pdb:6KDY|rcsb pdb:6KE3|rcsb pdb:6L57|rcsb pdb:6L59|rcsb pdb:7CE3|reactome:R-HSA-71403 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dtc0EOaZYDVEh5p1xgHE9uq2YVs9606 rogid:JvAUAMJ0DcgnIfvy/vlfRyXYzhE9606 rigid:kxVwRHZfspaP7sr3CSoR7I6fkAY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7LBC6 uniprotkb:Q01469 intact:EBI-2511832|ensembl:ENSP00000326563|uniprotkb:Q9BW93|uniprotkb:Q9BZ52|uniprotkb:Q9BVH6|uniprotkb:A6H8X7|uniprotkb:Q9UPS0|uniprotkb:Q9NYF4 intact:EBI-1054073|uniprotkb:B2R4K0|ensembl:ENSP00000297258 psi-mi:kdm3b_human(display_long)|uniprotkb:KDM3B(gene name)|psi-mi:KDM3B(display_short)|uniprotkb:C5orf7(gene name synonym)|uniprotkb:JHDM2B(gene name synonym)|uniprotkb:JMJD1B(gene name synonym)|uniprotkb:KIAA1082(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 2B(gene name synonym)|uniprotkb:Jumonji domain-containing protein 1B(gene name synonym)|uniprotkb:Nuclear protein 5qNCA(gene name synonym)|uniprotkb:"[histone H3]-dimethyl-L-lysine(9) demethylase 3B"(gene name synonym) psi-mi:fabp5_human(display_long)|uniprotkb:Epidermal-type fatty acid-binding protein(gene name synonym)|uniprotkb:Psoriasis-associated fatty acid-binding protein homolog(gene name synonym)|uniprotkb:FABP5(gene name)|psi-mi:FABP5(display_short)|uniprotkb:Fatty acid-binding protein, epidermal(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479861|imex:IM-26985-173 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120733(gene)|ensembl:ENST00000314358(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016209"(antioxidant activity)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0072718"(response to cisplatin)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q7LBC6|rcsb pdb:4C8D|rcsb pdb:5R7X|rcsb pdb:5RAA|rcsb pdb:5RAC|rcsb pdb:5RAD|rcsb pdb:5RAE|rcsb pdb:5RAF|rcsb pdb:5RAG|rcsb pdb:5RAH|rcsb pdb:5RAI|rcsb pdb:5RAJ|rcsb pdb:5RAK|rcsb pdb:5RAL|rcsb pdb:5RAM|rcsb pdb:5RAN|rcsb pdb:5RAO|rcsb pdb:5RAP|rcsb pdb:5RAQ|rcsb pdb:5RAR|rcsb pdb:5RAS|rcsb pdb:5RAB|rcsb pdb:5RAU|rcsb pdb:5RAV|rcsb pdb:5RAW|rcsb pdb:5RAX|rcsb pdb:5RAY|rcsb pdb:5RAZ|rcsb pdb:5RB0|rcsb pdb:5RB1|rcsb pdb:5RB2|rcsb pdb:5RB3|rcsb pdb:5RB4|rcsb pdb:5RB5|rcsb pdb:5RB6|rcsb pdb:5RB7|rcsb pdb:6RBJ|reactome:R-HSA-3214842|refseq:NP_057688.2 refseq:NP_001435.1|ensembl:ENSG00000164687(gene)|ensembl:ENST00000297258(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0008289"(lipid binding)|go:"GO:0008544"(epidermis development)|go:"GO:0010829"(negative regulation of glucose transmembrane transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031392"(regulation of prostaglandin biosynthetic process)|go:"GO:0035360"(positive regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099178"(regulation of retrograde trans-synaptic signaling by endocanabinoid)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990379"(lipid transport across blood-brain barrier)|interpro:IPR000463(Cytosolic fatty-acid binding)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR012674(Calycin)|interpro:IPR031259|mint:Q01469|rcsb pdb:1B56|rcsb pdb:1JJJ|rcsb pdb:4AZM|rcsb pdb:4AZR|rcsb pdb:4LKP|rcsb pdb:4LKT|rcsb pdb:5HZ5|rcsb pdb:5UR9|reactome:R-HSA-163560|reactome:R-HSA-5362517|reactome:R-HSA-6798695 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dtc0EOaZYDVEh5p1xgHE9uq2YVs9606 rogid:vxp81/mezHcm5oo27QOmAM8Y5dI9606 rigid:kxVwRHZfspaP7sr3CSoR7I6fkAY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7LBC6 uniprotkb:O75131 intact:EBI-2511832|ensembl:ENSP00000326563|uniprotkb:Q9BW93|uniprotkb:Q9BZ52|uniprotkb:Q9BVH6|uniprotkb:A6H8X7|uniprotkb:Q9UPS0|uniprotkb:Q9NYF4 intact:EBI-718988|uniprotkb:Q8IYA1|uniprotkb:A8KA47|ensembl:ENSP00000477590 psi-mi:kdm3b_human(display_long)|uniprotkb:KDM3B(gene name)|psi-mi:KDM3B(display_short)|uniprotkb:C5orf7(gene name synonym)|uniprotkb:JHDM2B(gene name synonym)|uniprotkb:JMJD1B(gene name synonym)|uniprotkb:KIAA1082(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 2B(gene name synonym)|uniprotkb:Jumonji domain-containing protein 1B(gene name synonym)|uniprotkb:Nuclear protein 5qNCA(gene name synonym)|uniprotkb:"[histone H3]-dimethyl-L-lysine(9) demethylase 3B"(gene name synonym) psi-mi:cpne3_human(display_long)|uniprotkb:Copine III(gene name synonym)|uniprotkb:CPNE3(gene name)|psi-mi:CPNE3(display_short)|uniprotkb:CPN3(gene name synonym)|uniprotkb:KIAA0636(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479861|imex:IM-26985-173 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120733(gene)|ensembl:ENST00000314358(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016209"(antioxidant activity)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0072718"(response to cisplatin)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q7LBC6|rcsb pdb:4C8D|rcsb pdb:5R7X|rcsb pdb:5RAA|rcsb pdb:5RAC|rcsb pdb:5RAD|rcsb pdb:5RAE|rcsb pdb:5RAF|rcsb pdb:5RAG|rcsb pdb:5RAH|rcsb pdb:5RAI|rcsb pdb:5RAJ|rcsb pdb:5RAK|rcsb pdb:5RAL|rcsb pdb:5RAM|rcsb pdb:5RAN|rcsb pdb:5RAO|rcsb pdb:5RAP|rcsb pdb:5RAQ|rcsb pdb:5RAR|rcsb pdb:5RAS|rcsb pdb:5RAB|rcsb pdb:5RAU|rcsb pdb:5RAV|rcsb pdb:5RAW|rcsb pdb:5RAX|rcsb pdb:5RAY|rcsb pdb:5RAZ|rcsb pdb:5RB0|rcsb pdb:5RB1|rcsb pdb:5RB2|rcsb pdb:5RB3|rcsb pdb:5RB4|rcsb pdb:5RB5|rcsb pdb:5RB6|rcsb pdb:5RB7|rcsb pdb:6RBJ|reactome:R-HSA-3214842|refseq:NP_057688.2 refseq:NP_003900.1|refseq:XP_005251150.1|ensembl:ENSG00000085719(gene)|ensembl:ENST00000517490(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071363"(cellular response to growth factor stimulus)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR010734(Copine)|interpro:IPR035892|interpro:IPR036465|interpro:IPR037768|mint:O75131|reactome:R-HSA-1483206|reactome:R-HSA-6798695|refseq:XP_016869434.1 - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dtc0EOaZYDVEh5p1xgHE9uq2YVs9606 rogid:75lb/sKHpJYCwCLIq973pzNMfzw9606 rigid:kxVwRHZfspaP7sr3CSoR7I6fkAY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7LBC6 uniprotkb:P01040 intact:EBI-2511832|ensembl:ENSP00000326563|uniprotkb:Q9BW93|uniprotkb:Q9BZ52|uniprotkb:Q9BVH6|uniprotkb:A6H8X7|uniprotkb:Q9UPS0|uniprotkb:Q9NYF4 intact:EBI-724303|ensembl:ENSP00000264474|uniprotkb:Q6IB90 psi-mi:kdm3b_human(display_long)|uniprotkb:KDM3B(gene name)|psi-mi:KDM3B(display_short)|uniprotkb:C5orf7(gene name synonym)|uniprotkb:JHDM2B(gene name synonym)|uniprotkb:JMJD1B(gene name synonym)|uniprotkb:KIAA1082(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 2B(gene name synonym)|uniprotkb:Jumonji domain-containing protein 1B(gene name synonym)|uniprotkb:Nuclear protein 5qNCA(gene name synonym)|uniprotkb:"[histone H3]-dimethyl-L-lysine(9) demethylase 3B"(gene name synonym) psi-mi:cyta_human(display_long)|uniprotkb:Cystatin-AS(gene name synonym)|uniprotkb:Stefin-A(gene name synonym)|uniprotkb:CSTA(gene name)|psi-mi:CSTA(display_short)|uniprotkb:STF1(gene name synonym)|uniprotkb:STFA(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479861|imex:IM-26985-173 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120733(gene)|ensembl:ENST00000314358(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016209"(antioxidant activity)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0072718"(response to cisplatin)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q7LBC6|rcsb pdb:4C8D|rcsb pdb:5R7X|rcsb pdb:5RAA|rcsb pdb:5RAC|rcsb pdb:5RAD|rcsb pdb:5RAE|rcsb pdb:5RAF|rcsb pdb:5RAG|rcsb pdb:5RAH|rcsb pdb:5RAI|rcsb pdb:5RAJ|rcsb pdb:5RAK|rcsb pdb:5RAL|rcsb pdb:5RAM|rcsb pdb:5RAN|rcsb pdb:5RAO|rcsb pdb:5RAP|rcsb pdb:5RAQ|rcsb pdb:5RAR|rcsb pdb:5RAS|rcsb pdb:5RAB|rcsb pdb:5RAU|rcsb pdb:5RAV|rcsb pdb:5RAW|rcsb pdb:5RAX|rcsb pdb:5RAY|rcsb pdb:5RAZ|rcsb pdb:5RB0|rcsb pdb:5RB1|rcsb pdb:5RB2|rcsb pdb:5RB3|rcsb pdb:5RB4|rcsb pdb:5RB5|rcsb pdb:5RB6|rcsb pdb:5RB7|rcsb pdb:6RBJ|reactome:R-HSA-3214842|refseq:NP_057688.2 refseq:NP_005204.1|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR001713(Proteinase inhibitor I25A, stefin A)|mint:P01040|rcsb pdb:1CYU|rcsb pdb:1CYV|rcsb pdb:1DVC|rcsb pdb:1DVD|rcsb pdb:1GD3|rcsb pdb:1GD4|rcsb pdb:1N9J|rcsb pdb:1NB3|rcsb pdb:1NB5|rcsb pdb:3K9M|rcsb pdb:3KFQ|interpro:IPR018073|rcsb pdb:3KSE|reactome:R-HSA-6809371|ensembl:ENSG00000121552(gene)|ensembl:ENST00000264474(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002020"(protease binding)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0045861"(negative regulation of proteolysis) - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dtc0EOaZYDVEh5p1xgHE9uq2YVs9606 rogid:SzbpyWUHlOtItIvffzuwhcqFsDI9606 rigid:kxVwRHZfspaP7sr3CSoR7I6fkAY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7LBC6 uniprotkb:Q15797 intact:EBI-2511832|ensembl:ENSP00000326563|uniprotkb:Q9BW93|uniprotkb:Q9BZ52|uniprotkb:Q9BVH6|uniprotkb:A6H8X7|uniprotkb:Q9UPS0|uniprotkb:Q9NYF4 intact:EBI-1567153|uniprotkb:Q16636|uniprotkb:D3DNZ9|uniprotkb:A8KAJ0|uniprotkb:Q9UFT8|ensembl:ENSP00000305769|ensembl:ENSP00000377652|ensembl:ENSP00000426568 psi-mi:kdm3b_human(display_long)|uniprotkb:KDM3B(gene name)|psi-mi:KDM3B(display_short)|uniprotkb:C5orf7(gene name synonym)|uniprotkb:JHDM2B(gene name synonym)|uniprotkb:JMJD1B(gene name synonym)|uniprotkb:KIAA1082(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 2B(gene name synonym)|uniprotkb:Jumonji domain-containing protein 1B(gene name synonym)|uniprotkb:Nuclear protein 5qNCA(gene name synonym)|uniprotkb:"[histone H3]-dimethyl-L-lysine(9) demethylase 3B"(gene name synonym) psi-mi:smad1_human(display_long)|uniprotkb:Mad-related protein 1(gene name synonym)|uniprotkb:SMAD family member 1(gene name synonym)|uniprotkb:Transforming growth factor-beta-signaling protein 1(gene name synonym)|uniprotkb:JV4-1(gene name synonym)|uniprotkb:SMAD1(gene name)|psi-mi:SMAD1(display_short)|uniprotkb:BSP1(gene name synonym)|uniprotkb:MADH1(gene name synonym)|uniprotkb:MADR1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479861|imex:IM-26985-173 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000120733(gene)|ensembl:ENST00000314358(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016209"(antioxidant activity)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0072718"(response to cisplatin)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q7LBC6|rcsb pdb:4C8D|rcsb pdb:5R7X|rcsb pdb:5RAA|rcsb pdb:5RAC|rcsb pdb:5RAD|rcsb pdb:5RAE|rcsb pdb:5RAF|rcsb pdb:5RAG|rcsb pdb:5RAH|rcsb pdb:5RAI|rcsb pdb:5RAJ|rcsb pdb:5RAK|rcsb pdb:5RAL|rcsb pdb:5RAM|rcsb pdb:5RAN|rcsb pdb:5RAO|rcsb pdb:5RAP|rcsb pdb:5RAQ|rcsb pdb:5RAR|rcsb pdb:5RAS|rcsb pdb:5RAB|rcsb pdb:5RAU|rcsb pdb:5RAV|rcsb pdb:5RAW|rcsb pdb:5RAX|rcsb pdb:5RAY|rcsb pdb:5RAZ|rcsb pdb:5RB0|rcsb pdb:5RB1|rcsb pdb:5RB2|rcsb pdb:5RB3|rcsb pdb:5RB4|rcsb pdb:5RB5|rcsb pdb:5RB6|rcsb pdb:5RB7|rcsb pdb:6RBJ|reactome:R-HSA-3214842|refseq:NP_057688.2 refseq:XP_006714280.1|refseq:NP_001003688.1|refseq:NP_005891.1|refseq:XP_011530263.1|refseq:XP_011530264.1|refseq:XP_011530265.1|refseq:XP_011530266.1|refseq:XP_005263049.1|ensembl:ENSP00000305769|ensembl:ENSP00000377652|ensembl:ENSP00000426568|dip:DIP-38538N|ensembl:ENSG00000170365(gene)|ensembl:ENST00000302085(transcript)|ensembl:ENST00000394092(transcript)|ensembl:ENST00000515385(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001710"(mesodermal cell fate commitment)|go:"GO:0002051"(osteoblast fate commitment)|go:"GO:0003161"(cardiac conduction system development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007183"(SMAD protein complex assembly)|go:"GO:0007276"(gamete generation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017151"(DEAD/H-box RNA helicase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042592"(homeostatic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051148"(negative regulation of muscle cell differentiation)|go:"GO:0051216"(cartilage development)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060348"(bone development)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061036"(positive regulation of cartilage development)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071141"(SMAD protein complex)|go:"GO:0071144"(heteromeric SMAD protein complex)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:1901522"(positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|interpro:IPR001132(SMAD domain, Dwarfin-type)|interpro:IPR003619(MAD homology 1, Dwarfin-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013019(MAD homology, MH1)|interpro:IPR013790(Dwarfin)|interpro:IPR017855(SMAD domain-like)|interpro:IPR036578|mint:Q15797|rcsb pdb:1KHU|rcsb pdb:2LAW|rcsb pdb:2LAX|rcsb pdb:2LAY|rcsb pdb:2LAZ|rcsb pdb:2LB0|rcsb pdb:2LB1|rcsb pdb:3Q47|rcsb pdb:3Q4A|rcsb pdb:5ZOK|reactome:R-HSA-201451|reactome:R-HSA-5689880|reactome:R-HSA-8941326 - - comment:"author score: 31" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dtc0EOaZYDVEh5p1xgHE9uq2YVs9606 rogid:cdDNFpwLw2+hPeP0l6ArvDs3LMo9606 rigid:kxVwRHZfspaP7sr3CSoR7I6fkAY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R0 uniprotkb:P18754 intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710 intact:EBI-992720|uniprotkb:Q16269|uniprotkb:Q6NT97|ensembl:ENSP00000362939|ensembl:ENSP00000381931|ensembl:ENSP00000508074|ensembl:ENSP00000362938 psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym) psi-mi:rcc1_human(display_long)|uniprotkb:Chromosome condensation protein 1(gene name synonym)|uniprotkb:Cell cycle regulatory protein(gene name synonym)|uniprotkb:RCC1(gene name)|psi-mi:RCC1(display_short)|uniprotkb:CHC1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479978|imex:IM-26985-249 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886 refseq:NP_001041659.1|refseq:NP_001041660.1|refseq:NP_001041664.1|refseq:NP_001260.1|dip:DIP-35416N|ensembl:ENSG00000180198(gene)|ensembl:ENST00000373832(transcript)|ensembl:ENST00000373833(transcript)|ensembl:ENST00000398958(transcript)|ensembl:ENST00000683442(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003682"(chromatin binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0016032"(viral process)|rcsb pdb:5E1B|rcsb pdb:5E1D|rcsb pdb:5E1M|rcsb pdb:5E1O|rcsb pdb:5E2A|go:"GO:0031267"(small GTPase binding)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031492"(nucleosomal DNA binding)|rcsb pdb:5E2B|rcsb pdb:5TBK|rcsb pdb:6DUB|reactome:R-HSA-165054|go:"GO:0031965"(nuclear membrane)|reactome:R-HSA-180746|reactome:R-HSA-9615933|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043199"(sulfate binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|mint:P18754|rcsb pdb:1A12|rcsb pdb:1I2M - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606 rogid:/gP2xQp6fUffHTXpXvs8eb5YJ209606 rigid:xeOafV2Ssbob1sUqXUO1IuOoquw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R0 uniprotkb:P56545 intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710 intact:EBI-741533|uniprotkb:O43449|uniprotkb:Q5SQP7|uniprotkb:Q69YI3|uniprotkb:Q86SV0|uniprotkb:Q9H2T8|uniprotkb:A8K2X5|ensembl:ENSP00000338615|ensembl:ENSP00000410474|ensembl:ENSP00000434630|ensembl:ENSP00000436285|uniprotkb:D3DRF5|uniprotkb:Q8IY44|intact:EBI-11742664 psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym) psi-mi:ctbp2_human(display_long)|uniprotkb:CTBP2(gene name)|psi-mi:CTBP2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479978|imex:IM-26985-249 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886 refseq:NP_001077383.1|refseq:NP_001320.1|refseq:NP_073713.2|refseq:NP_001307943.1|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098882"(structural constituent of presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:P56545|rcsb pdb:2OME|rcsb pdb:4LCJ|rcsb pdb:6WKW|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-9662360|go:"GO:0048386"(positive regulation of retinoic acid receptor signaling pathway)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0098684"(photoreceptor ribbon synapse)|ensembl:ENSG00000175029(gene)|ensembl:ENST00000337195(transcript)|ensembl:ENST00000411419(transcript)|ensembl:ENST00000494626(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|ensembl:ENST00000531469(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019079"(viral genome replication)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|refseq:XP_011537653.1|refseq:XP_011537655.1|refseq:XP_011537656.1|refseq:XP_011537657.1|refseq:NP_001307941.1|refseq:NP_001307942.1|refseq:XP_005269618.1|refseq:XP_005269621.1|refseq:XP_005269624.1|refseq:XP_005269625.1|refseq:XP_005269626.1|refseq:XP_005269628.1|refseq:XP_005269629.1|refseq:NP_001277143.1|refseq:NP_001277144.1|refseq:XP_006717705.1|refseq:XP_016871245.1|refseq:XP_016871246.1|dip:DIP-42104N|refseq:XP_011537651.1 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606 rogid:6sKiqjMRW/ViEvTbQJoaUjgvZtc9606 rigid:xeOafV2Ssbob1sUqXUO1IuOoquw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R0 uniprotkb:P01040 intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710 intact:EBI-724303|ensembl:ENSP00000264474|uniprotkb:Q6IB90 psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym) psi-mi:cyta_human(display_long)|uniprotkb:Cystatin-AS(gene name synonym)|uniprotkb:Stefin-A(gene name synonym)|uniprotkb:CSTA(gene name)|psi-mi:CSTA(display_short)|uniprotkb:STF1(gene name synonym)|uniprotkb:STFA(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479978|imex:IM-26985-249 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886 refseq:NP_005204.1|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR001713(Proteinase inhibitor I25A, stefin A)|mint:P01040|rcsb pdb:1CYU|rcsb pdb:1CYV|rcsb pdb:1DVC|rcsb pdb:1DVD|rcsb pdb:1GD3|rcsb pdb:1GD4|rcsb pdb:1N9J|rcsb pdb:1NB3|rcsb pdb:1NB5|rcsb pdb:3K9M|rcsb pdb:3KFQ|interpro:IPR018073|rcsb pdb:3KSE|reactome:R-HSA-6809371|ensembl:ENSG00000121552(gene)|ensembl:ENST00000264474(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002020"(protease binding)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0045861"(negative regulation of proteolysis) - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606 rogid:SzbpyWUHlOtItIvffzuwhcqFsDI9606 rigid:xeOafV2Ssbob1sUqXUO1IuOoquw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R0 uniprotkb:Q5UIP0 intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710 intact:EBI-711331|uniprotkb:A6NC27|uniprotkb:C9JBR1|uniprotkb:Q5H9R3|uniprotkb:Q5UIP2|uniprotkb:Q66YK6|uniprotkb:Q6PRU2|uniprotkb:Q8TE94|uniprotkb:Q99772|uniprotkb:Q9H830|uniprotkb:Q9H9B9|uniprotkb:Q9NVP5|uniprotkb:Q9Y4R4|ensembl:ENSP00000243326|ensembl:ENSP00000390181 psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym) psi-mi:rif1_human(display_long)|uniprotkb:RIF1(gene name)|psi-mi:RIF1(display_short)|uniprotkb:Rap1-interacting factor 1 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479978|imex:IM-26985-249 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886 go:"GO:0007049"(cell cycle)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043247"(telomere maintenance in response to DNA damage)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0051233"(spindle midzone)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022031|interpro:IPR028566|mint:Q5UIP0|reactome:R-HSA-5693571|ensembl:ENSG00000080345(gene)|ensembl:ENST00000243326(transcript)|ensembl:ENST00000444746(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0006974"(cellular response to DNA damage stimulus)|refseq:NP_001171134.1|refseq:NP_001171135.1|refseq:NP_001171136.1|refseq:NP_060621.3|refseq:XP_005246722.1 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606 rogid:XM3dyJZ0U4P2OUvgW3LOX2MLRDs9606 rigid:xeOafV2Ssbob1sUqXUO1IuOoquw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R0 uniprotkb:P11171 intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710 intact:EBI-1050906|uniprotkb:P11176|uniprotkb:Q14245|uniprotkb:Q5TB35|uniprotkb:Q5VXN8|uniprotkb:Q8IXV9|uniprotkb:Q9Y578|uniprotkb:Q9Y579|uniprotkb:B1ALH8|uniprotkb:B1ALH9|uniprotkb:D3DPM9|uniprotkb:D3DPN0|ensembl:ENSP00000345259|ensembl:ENSP00000362904 psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym) psi-mi:epb41_human(display_long)|uniprotkb:Band 4.1(gene name synonym)|uniprotkb:EPB4.1(gene name synonym)|uniprotkb:4.1R(gene name synonym)|uniprotkb:EPB41(gene name)|psi-mi:EPB41(display_short)|uniprotkb:E41P(gene name synonym)|uniprotkb:Erythrocyte membrane protein band 4.1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479978|imex:IM-26985-249 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886 refseq:NP_001159477.1|refseq:NP_001159478.1|refseq:NP_004428.1|refseq:NP_976217.1|refseq:XP_016856078.1|refseq:XP_005245818.1|refseq:XP_005245821.1|ensembl:ENSG00000159023(gene)|ensembl:ENST00000343067(transcript)|ensembl:ENST00000373798(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030507"(spectrin binding)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045171"(intercellular bridge)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0072686"(mitotic spindle)|go:"GO:0099738"(cell cortex region)|go:"GO:1904478"(regulation of intestinal absorption)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR007477(SAB)|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR021187|interpro:IPR029071|interpro:IPR035963|mint:P11171|rcsb pdb:1GG3|rcsb pdb:2RQ1|rcsb pdb:3QIJ|reactome:R-HSA-6794361|dip:DIP-17032N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606 rogid:ZCaM+kjScfGP23wRkFRwVyxOyvk9606 rigid:xeOafV2Ssbob1sUqXUO1IuOoquw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R0 uniprotkb:Q14247 intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710 intact:EBI-351886|intact:EBI-3959948|ensembl:ENSP00000301843|ensembl:ENSP00000500756|uniprotkb:Q8N707|uniprotkb:Q96H99 psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym) psi-mi:src8_human(display_long)|uniprotkb:CTTN(gene name)|psi-mi:CTTN(display_short)|uniprotkb:EMS1(gene name synonym)|uniprotkb:Amplaxin(gene name synonym)|uniprotkb:Oncogene EMS1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479978|imex:IM-26985-249 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886 refseq:NP_005222.2|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097581"(lamellipodium organization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR015503(Cortactin)|interpro:IPR035716|interpro:IPR036028|mint:Q14247|rcsb pdb:1X69|rcsb pdb:2D1X|reactome:R-HSA-5627123|reactome:R-HSA-8856828|ensembl:ENSG00000085733(gene)|ensembl:ENSG00000288401(gene)|ensembl:ENST00000301843(transcript)|ensembl:ENST00000671805(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|refseq:NP_001171669.1|refseq:NP_612632.1|dip:DIP-33190N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606 rogid:uzhAnL5Fu9Mgg9/LWeNiaYIwNVU9606 rigid:xeOafV2Ssbob1sUqXUO1IuOoquw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R0 uniprotkb:O43707 intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710 intact:EBI-351526|uniprotkb:O76048|uniprotkb:D6PXK4|ensembl:ENSP00000252699|ensembl:ENSP00000489220|uniprotkb:A4K467 psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym) psi-mi:actn4_human(display_long)|uniprotkb:ACTN4(gene name)|psi-mi:ACTN4(display_short)|uniprotkb:Non-muscle alpha-actinin 4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479978|imex:IM-26985-249 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886 refseq:NP_004915.2|ensembl:ENSG00000130402(gene)|ensembl:ENSG00000282844(gene)|ensembl:ENST00000252699(transcript)|ensembl:ENST00000634960(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001882"(nucleoside binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0015031"(protein transport)|go:"GO:0016604"(nuclear body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031143"(pseudopodium)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032417"("positive regulation of sodium:proton antiporter activity")|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900025"(negative regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1903506"(regulation of nucleic acid-templated transcription)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR036872|mint:O43707|rcsb pdb:1WLX|rcsb pdb:1YDI|rcsb pdb:2R0O|rcsb pdb:6O31|rcsb pdb:6OA6|reactome:R-HSA-114608|reactome:R-HSA-373753|dip:DIP-33179N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606 rogid:kTYezA2lEtL/AQPfCQ8BE79nzow9606 rigid:xeOafV2Ssbob1sUqXUO1IuOoquw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R0 uniprotkb:P19474 intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710 intact:EBI-81290|uniprotkb:Q96RF8|uniprotkb:Q5XPV5|ensembl:ENSP00000254436 psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym) psi-mi:ro52_human(display_long)|uniprotkb:TRIM21(gene name)|psi-mi:TRIM21(display_short)|uniprotkb:RNF81(gene name synonym)|uniprotkb:Sjoegren syndrome type A antigen(gene name synonym)|uniprotkb:"Ro(SS-A)"(gene name synonym)|uniprotkb:52 kDa ribonucleoprotein autoantigen Ro/SS-A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 21(gene name synonym)|uniprotkb:RING finger protein 81(gene name synonym)|uniprotkb:52 kDa Ro protein(gene name synonym)|uniprotkb:RO52(gene name synonym)|uniprotkb:SSA1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM21(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479978|imex:IM-26985-249 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886 refseq:NP_003132.2|go:"GO:0019901"(protein kinase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031648"(protein destabilization)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090086"(negative regulation of protein deubiquitination)|ensembl:ENSG00000132109(gene)|ensembl:ENST00000254436(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000932"(P-body)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035831|interpro:IPR043136|mint:P19474|rcsb pdb:2IWG|rcsb pdb:5JPX|rcsb pdb:5OLM|rcsb pdb:6FGA|rcsb pdb:6S53|rcsb pdb:7BBD|reactome:R-HSA-1834941|reactome:R-HSA-3134975|reactome:R-HSA-877300|reactome:R-HSA-983168|go:"GO:1902187"|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003613(U box)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like) - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606 rogid:/9rpwdudXQWv8z8JLmRecXf3YQM9606 rigid:xeOafV2Ssbob1sUqXUO1IuOoquw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R0 uniprotkb:Q9Y2J2 intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710 intact:EBI-310986|uniprotkb:O95713|uniprotkb:Q9BRP5|ensembl:ENSP00000343158|uniprotkb:B7Z4I5|uniprotkb:F5GX05 psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym) psi-mi:e41l3_human(display_long)|uniprotkb:EPB41L3(gene name)|psi-mi:EPB41L3(display_short)|uniprotkb:DAL1(gene name synonym)|uniprotkb:KIAA0987(gene name synonym)|uniprotkb:4.1B(gene name synonym)|uniprotkb:Differentially expressed in adenocarcinoma of the lung protein 1(gene name synonym)|uniprotkb:Erythrocyte membrane protein band 4.1-like 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479978|imex:IM-26985-249 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886 refseq:NP_036439.2|refseq:NP_001268462.1|refseq:NP_001268463.1|refseq:NP_001268464.1|ensembl:ENSG00000082397(gene)|ensembl:ENST00000341928(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0002175"(protein localization to paranode region of axon)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030054"(cell junction)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030913"(paranodal junction assembly)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0033270"(paranode region of axon)|go:"GO:0043217"(myelin maintenance)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0071205"(protein localization to juxtaparanode region of axon)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0106006"(cytoskeletal protein-membrane anchor activity)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR007477(SAB)|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR030691|interpro:IPR035963|mint:Q9Y2J2|rcsb pdb:2HE7|rcsb pdb:3BIN|rcsb pdb:5RYM|rcsb pdb:5RYN|rcsb pdb:5RYO|rcsb pdb:5RYP|rcsb pdb:5RYQ|rcsb pdb:5RYR|rcsb pdb:5RYS|rcsb pdb:5RYT|rcsb pdb:5RYU|rcsb pdb:5RYV|rcsb pdb:5RYW|rcsb pdb:5RYX|rcsb pdb:5RYY|rcsb pdb:5RYZ|rcsb pdb:5RZ0|rcsb pdb:5RZ1|rcsb pdb:5RZ2|rcsb pdb:5RZ3|rcsb pdb:5RZ4|rcsb pdb:5RZ5|rcsb pdb:5RZ6|rcsb pdb:5RZ7|rcsb pdb:5RZ8|rcsb pdb:5RZ9|rcsb pdb:5RZA|rcsb pdb:5RZB|rcsb pdb:5RZC|rcsb pdb:5RZD|rcsb pdb:5RZE|rcsb pdb:5RZF|rcsb pdb:5RZG|rcsb pdb:5RZH|rcsb pdb:5RZI|rcsb pdb:5RZJ|rcsb pdb:5RZK|rcsb pdb:5RZL|rcsb pdb:5RZM|rcsb pdb:5RZN|rcsb pdb:5RZO|rcsb pdb:5RZP|rcsb pdb:5RZQ|rcsb pdb:5RZR|rcsb pdb:5RZS|rcsb pdb:5RZT|rcsb pdb:5RZU|rcsb pdb:5RZV|rcsb pdb:5RZW|rcsb pdb:5RZX|rcsb pdb:5RZY|rcsb pdb:5RZZ|rcsb pdb:5S00|rcsb pdb:6IBE|reactome:R-HSA-6794361|reactome:R-HSA-9662360|reactome:R-HSA-9662361|refseq:XP_016881125.1|dip:DIP-17035N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606 rogid:Uwq5dqLRdgFLPBhXZROSRJstl709606 rigid:xeOafV2Ssbob1sUqXUO1IuOoquw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R0 uniprotkb:P46060 intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710 intact:EBI-396091|uniprotkb:Q96JJ2|ensembl:ENSP00000401470|ensembl:ENSP00000348577|ensembl:ENSP00000385866 psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym) psi-mi:ragp1_human(display_long)|uniprotkb:RANGAP1(gene name)|psi-mi:RANGAP1(display_short)|uniprotkb:KIAA1835(gene name synonym)|uniprotkb:SD(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479978|imex:IM-26985-249 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886 refseq:NP_002874.1|ensembl:ENST00000356244(transcript)|ensembl:ENST00000405486(transcript)|ensembl:ENST00000455915(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0016235"(aggresome)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|refseq:XP_011528596.1|refseq:XP_011528597.1|refseq:NP_001304859.1|go:"GO:0031965"(nuclear membrane)|interpro:IPR009109(Ran-GTPase activating protein 1, C-terminal)|interpro:IPR032675|interpro:IPR036720|mint:P46060|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2IO2|rcsb pdb:2IO3|rcsb pdb:2IY0|rcsb pdb:3UIN|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:5D2M|reactome:R-HSA-141444|reactome:R-HSA-165054|reactome:R-HSA-2467813|interpro:IPR001611(Leucine-rich repeat)|reactome:R-HSA-2500257|reactome:R-HSA-3108232|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0045296"(cadherin binding)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048678"(response to axon injury)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1904117"(cellular response to vasopressin)|go:"GO:1990723"(cytoplasmic periphery of the nuclear pore complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|ensembl:ENSG00000100401(gene)|refseq:XP_006724352.1|reactome:R-HSA-4615885|refseq:NP_001265580.1|reactome:R-HSA-68877|reactome:R-HSA-9615933|reactome:R-HSA-9648025|reactome:R-HSA-5663220|refseq:XP_016884382.1|refseq:XP_016884383.1|refseq:XP_016884384.1|refseq:XP_016884385.1|refseq:XP_016884386.1|dip:DIP-29079N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606 rogid:pUpd+7p5CeAKaRGLo/bXTeiwjiM9606 rigid:xeOafV2Ssbob1sUqXUO1IuOoquw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R0 uniprotkb:P36957 intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710 intact:EBI-351007|uniprotkb:Q9BQ32|uniprotkb:Q7LDY7|intact:EBI-2511564|uniprotkb:B7Z5W8|uniprotkb:E7ESY5|ensembl:ENSP00000335304 psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym) psi-mi:odo2_human(display_long)|uniprotkb:DLST(gene name)|psi-mi:DLST(display_short)|uniprotkb:DLTS(gene name synonym)|uniprotkb:Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex(gene name synonym)|uniprotkb:E2K(gene name synonym)|uniprotkb:2-oxoglutarate dehydrogenase complex component E2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479978|imex:IM-26985-249 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886 refseq:NP_001924.2|ensembl:ENSG00000119689(gene)|ensembl:ENST00000334220(transcript)|go:"GO:0004149"(dihydrolipoyllysine-residue succinyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006104"(succinyl-CoA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0033512"(L-lysine catabolic process to acetyl-CoA via saccharopine)|go:"GO:0034451"(centriolar satellite)|go:"GO:0045252"(oxoglutarate dehydrogenase complex)|go:"GO:0106077"(histone succinylation)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR006255(Dihydrolipoamide succinyltransferase)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|mint:P36957|rcsb pdb:6H05|reactome:R-HSA-389661|reactome:R-HSA-71064|reactome:R-HSA-71403 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606 rogid:lZLUcTHB/dxXBTI/IXnSjyuVmBo9606 rigid:xeOafV2Ssbob1sUqXUO1IuOoquw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R0 uniprotkb:P00367 intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710 intact:EBI-356544|uniprotkb:Q5TBU3|ensembl:ENSP00000277865|uniprotkb:B3KV55|uniprotkb:B4DGN5 psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym) psi-mi:dhe3_human(display_long)|uniprotkb:GLUD1(gene name)|psi-mi:GLUD1(display_short)|uniprotkb:GLUD(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479978|imex:IM-26985-249 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886 ensembl:ENSG00000148672(gene)|ensembl:ENST00000277865(transcript)|go:"GO:0004352"("glutamate dehydrogenase (NAD+) activity")|go:"GO:0004353"("glutamate dehydrogenase [NAD(P)+] activity")|go:"GO:0004354"("glutamate dehydrogenase (NADP+) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006537"(glutamate biosynthetic process)|go:"GO:0006538"(glutamate catabolic process)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0021762"(substantia nigra development)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0042802"(identical protein binding)|refseq:NP_005262.1|refseq:NP_001305829.1|refseq:NP_001305830.1|refseq:NP_001305831.1|refseq:NP_001305833.1|refseq:NP_001305834.1|refseq:NP_001305835.1|go:"GO:0043531"(ADP binding)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070728"(leucine binding)|go:"GO:0072350"(tricarboxylic acid metabolic process)|interpro:IPR006095(Glutamate/phenylalanine/leucine/valine dehydrogenase)|interpro:IPR006096(Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal)|interpro:IPR006097(Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation region)|interpro:IPR033524|interpro:IPR033922|interpro:IPR036291|mint:P00367|rcsb pdb:1L1F|rcsb pdb:1NR1|rcsb pdb:6DQG|reactome:R-HSA-2151201|reactome:R-HSA-8964539 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606 rogid:rWYi7otiOLlUvfEl7Vy6ELkY+BM9606 rigid:xeOafV2Ssbob1sUqXUO1IuOoquw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R0 uniprotkb:Q12931 intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710 intact:EBI-1055869|uniprotkb:O43642|uniprotkb:O75235|uniprotkb:Q9UHL5|uniprotkb:B4DR68|uniprotkb:F5H897|uniprotkb:D3DUC8|ensembl:ENSP00000246957 psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym) psi-mi:trap1_human(display_long)|uniprotkb:TRAP1(gene name)|psi-mi:TRAP1(display_short)|uniprotkb:HSP75(gene name synonym)|uniprotkb:Tumor necrosis factor type 1 receptor-associated protein(gene name synonym)|uniprotkb:TNFR-associated protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479978|imex:IM-26985-249 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886 refseq:NP_057376.2|refseq:NP_001258978.1|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0009386"(translational attenuation)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:1901856"(negative regulation of cellular respiration)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1903751"(negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:Q12931|rcsb pdb:4Z1F|rcsb pdb:4Z1G|rcsb pdb:4Z1H|rcsb pdb:4Z1I|rcsb pdb:5F3K|rcsb pdb:5F5R|rcsb pdb:5HPH|rcsb pdb:5Y3N|rcsb pdb:5Y3O|rcsb pdb:6XG6|rcsb pdb:7C04|rcsb pdb:7C05|rcsb pdb:7C7B|rcsb pdb:7C7C|reactome:R-HSA-611105|ensembl:ENSG00000126602(gene)|ensembl:ENST00000246957(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|dip:DIP-6250N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606 rogid:O/i+7vgZQcDQF3xJTeqNLbWiQ8U9606 rigid:xeOafV2Ssbob1sUqXUO1IuOoquw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R0 uniprotkb:P27824 intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710 intact:EBI-355947|uniprotkb:D3DWQ3|uniprotkb:B2R5V8|ensembl:ENSP00000421434|ensembl:ENSP00000421813|ensembl:ENSP00000424063|ensembl:ENSP00000424745|ensembl:ENSP00000491760|ensembl:ENSP00000492372|ensembl:ENSP00000492868|ensembl:ENSP00000505013|ensembl:ENSP00000505202|ensembl:ENSP00000505526|ensembl:ENSP00000505960|ensembl:ENSP00000506003|ensembl:ENSP00000506021|ensembl:ENSP00000506061|ensembl:ENSP00000506078|ensembl:ENSP00000506509|ensembl:ENSP00000506568|ensembl:ENSP00000506583|ensembl:ENSP00000247461|ensembl:ENSP00000391646|intact:EBI-9513217|uniprotkb:B4DGP8|uniprotkb:B4E2T8|uniprotkb:D6R9K3 psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym) psi-mi:calx_human(display_long)|uniprotkb:CANX(gene name)|psi-mi:CANX(display_short)|uniprotkb:Major histocompatibility complex class I antigen-binding protein p88(gene name synonym)|uniprotkb:p90(gene name synonym)|uniprotkb:IP90(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479978|imex:IM-26985-249 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886 refseq:NP_001019820.1|refseq:NP_001737.1|refseq:XP_011532967.1|go:"GO:0099059"(integral component of presynaptic active zone membrane)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27824|reactome:R-HSA-168316|reactome:R-HSA-2132295|reactome:R-HSA-8984722|reactome:R-HSA-901042|reactome:R-HSA-9020956|reactome:R-HSA-9683686|reactome:R-HSA-9694548|reactome:R-HSA-983170|ensembl:ENST00000452673(transcript)|ensembl:ENST00000502296(transcript)|ensembl:ENST00000504734(transcript)|ensembl:ENST00000509563(transcript)|ensembl:ENST00000513246(transcript)|ensembl:ENST00000638425(transcript)|ensembl:ENST00000638706(transcript)|ensembl:ENST00000639938(transcript)|ensembl:ENST00000680013(transcript)|ensembl:ENST00000680042(transcript)|ensembl:ENST00000680092(transcript)|ensembl:ENST00000680618(transcript)|ensembl:ENST00000681072(transcript)|ensembl:ENST00000681168(transcript)|ensembl:ENST00000681476(transcript)|ensembl:ENST00000681674(transcript)|ensembl:ENST00000681712(transcript)|ensembl:ENST00000681733(transcript)|ensembl:ENST00000681903(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|ensembl:ENST00000247461(transcript)|go:"GO:0005840"(ribosome)|go:"GO:0006457"(protein folding)|go:"GO:0007568"(aging)|go:"GO:0009306"(protein secretion)|go:"GO:0016020"(membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030424"(axon)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042470"(melanosome)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044233"(mitochondria-associated endoplasmic reticulum membrane)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|ensembl:ENSG00000127022(gene)|ensembl:ENSG00000283777(gene)|dip:DIP-457N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606 rogid:Vy9HZjl19IXifyFpueW0LXi9ENk9606 rigid:xeOafV2Ssbob1sUqXUO1IuOoquw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R0 uniprotkb:Q05639 intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710 intact:EBI-354943|ensembl:ENSP00000217182|uniprotkb:P54266|uniprotkb:Q0VGC7|uniprotkb:B5BUF3|uniprotkb:E1P5J1 psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym) psi-mi:ef1a2_human(display_long)|uniprotkb:EEF1A2(gene name)|psi-mi:EEF1A2(display_short)|uniprotkb:EEF1AL(gene name synonym)|uniprotkb:STN(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-2(gene name synonym)|uniprotkb:Statin-S1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479978|imex:IM-26985-249 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886 ensembl:ENSG00000101210(gene)|ensembl:ENST00000217182(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0090218"(positive regulation of lipid kinase activity)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:Q05639|rcsb pdb:3C5J|reactome:R-HSA-156842|refseq:NP_001949.1|dip:DIP-40060N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606 rogid:vFXfcSRokxKo5RW0tRE1qEK0NKw9606 rigid:xeOafV2Ssbob1sUqXUO1IuOoquw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R0 uniprotkb:P00918 intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710 intact:EBI-724062|ensembl:ENSP00000285379|uniprotkb:Q6FI12|uniprotkb:Q96ET9|uniprotkb:B2R7G8 psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym) psi-mi:cah2_human(display_long)|uniprotkb:Carbonic anhydrase II(gene name synonym)|uniprotkb:Carbonate dehydratase II(gene name synonym)|uniprotkb:Carbonic anhydrase C(gene name synonym)|uniprotkb:CA2(gene name)|psi-mi:CA2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479978|imex:IM-26985-249 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886 refseq:NP_000058.1|rcsb pdb:5YUI|rcsb pdb:5YUJ|rcsb pdb:5U0G|rcsb pdb:5YUK|rcsb pdb:5ZXW|rcsb pdb:6B4D|rcsb pdb:6B59|rcsb pdb:5ULN|rcsb pdb:6B5A|rcsb pdb:6BBS|rcsb pdb:6BC9|rcsb pdb:6BCC|rcsb pdb:6C7W|rcsb pdb:6C7X|rcsb pdb:6CA2|rcsb pdb:6CEH|rcsb pdb:6CJV|rcsb pdb:6D1L|rcsb pdb:6D1M|rcsb pdb:5UMC|rcsb pdb:5VGY|rcsb pdb:6E8P|rcsb pdb:6E8X|rcsb pdb:6E91|rcsb pdb:6E92|rcsb pdb:6EBE|rcsb pdb:6ECZ|rcsb pdb:6EDA|rcsb pdb:6EEA|rcsb pdb:6EEH|rcsb pdb:6EEO|rcsb pdb:6EQU|rcsb pdb:5W8B|rcsb pdb:6FJI|rcsb pdb:5WEX|rcsb pdb:6FJJ|rcsb pdb:6G3Q|rcsb pdb:6G6T|rcsb pdb:6GCY|rcsb pdb:6GDC|rcsb pdb:6GM9|rcsb pdb:5WG7|rcsb pdb:5WGP|rcsb pdb:5WLR|rcsb pdb:6GOT|rcsb pdb:6GXB|rcsb pdb:5WLT|rcsb pdb:5WLU|rcsb pdb:5WLV|rcsb pdb:5Y2R|rcsb pdb:5Y2S|rcsb pdb:6GXE|rcsb pdb:6H29|rcsb pdb:6H2Z|rcsb pdb:6H33|rcsb pdb:6H34|rcsb pdb:6H3Q|rcsb pdb:6H6S|rcsb pdb:6HD2|rcsb pdb:1BV3|rcsb pdb:1CA2|rcsb pdb:1CA3|rcsb pdb:1CAH|rcsb pdb:1CAI|rcsb pdb:1CAJ|rcsb pdb:1CAK|rcsb pdb:1CAL|rcsb pdb:1CAM|rcsb pdb:1CAN|rcsb pdb:1CAO|rcsb pdb:1CAY|rcsb pdb:1CAZ|rcsb pdb:1CCS|rcsb pdb:1CCT|rcsb pdb:1CCU|rcsb pdb:1CIL|rcsb pdb:1CIM|rcsb pdb:1CIN|rcsb pdb:1CNB|rcsb pdb:1CNC|rcsb pdb:1CNG|rcsb pdb:1CNH|rcsb pdb:1CNI|rcsb pdb:1CNJ|rcsb pdb:1BNW|rcsb pdb:1CNK|rcsb pdb:1CNW|rcsb pdb:1CNX|rcsb pdb:1CNY|rcsb pdb:1CRA|rcsb pdb:1CVA|rcsb pdb:1CVB|rcsb pdb:1IF4|rcsb pdb:1IF5|rcsb pdb:1IF6|rcsb pdb:1IF7|rcsb pdb:1IF8|rcsb pdb:1IF9|rcsb pdb:1KWQ|rcsb pdb:1I9Q|rcsb pdb:1KWR|rcsb pdb:1LG5|rcsb pdb:1LG6|rcsb pdb:1LGD|rcsb pdb:1LUG|rcsb pdb:1LZV|rcsb pdb:1MOO|rcsb pdb:1MUA|rcsb pdb:1OKL|rcsb pdb:1OKM|rcsb pdb:1OKN|rcsb pdb:1OQ5|rcsb pdb:1RAY|rcsb pdb:1RAZ|rcsb pdb:1RZA|rcsb pdb:1RZB|rcsb pdb:1RZC|rcsb pdb:1RZD|rcsb pdb:1RZE|rcsb pdb:1T9N|rcsb pdb:1TB0|rcsb pdb:1TBT|rcsb pdb:1TE3|rcsb pdb:1TEQ|rcsb pdb:1TEU|rcsb pdb:6HR3|rcsb pdb:6HX5|rcsb pdb:6HXD|rcsb pdb:6HZX|rcsb pdb:6I0W|rcsb pdb:6I1U|rcsb pdb:6I2F|rcsb pdb:6I3E|rcsb pdb:6IC2|rcsb pdb:6KLZ|rcsb pdb:6KM0|rcsb pdb:6KM1|rcsb pdb:6KM2|rcsb pdb:6KM3|rcsb pdb:6KM4|rcsb pdb:6KM5|rcsb pdb:6KM6|rcsb pdb:6LUU|rcsb pdb:6LUV|rcsb pdb:6LUW|rcsb pdb:6LUX|rcsb pdb:6LUY|rcsb pdb:6LUZ|rcsb pdb:6LV1|rcsb pdb:6LV2|rcsb pdb:6LV3|rcsb pdb:6LV4|rcsb pdb:6LV5|rcsb pdb:6LV6|rcsb pdb:6LV7|rcsb pdb:6LV8|rcsb pdb:6LV9|rcsb pdb:6HQX|rcsb pdb:6LVA|rcsb pdb:6MBV|rcsb pdb:6MBY|rcsb pdb:6NLV|rcsb pdb:6NM0|rcsb pdb:6ODZ|rcsb pdb:6OE0|rcsb pdb:6OE1|rcsb pdb:6OTI|rcsb pdb:6OTK|rcsb pdb:6OTM|rcsb pdb:6OTO|rcsb pdb:6OTP|rcsb pdb:6OTQ|rcsb pdb:1CVC|rcsb pdb:1CVD|rcsb pdb:1CVE|rcsb pdb:1G46|rcsb pdb:1G48|rcsb pdb:1CVF|rcsb pdb:1CVH|rcsb pdb:1DCA|rcsb pdb:1DCB|rcsb pdb:1EOU|rcsb pdb:1F2W|rcsb pdb:1FQL|rcsb pdb:1FQM|rcsb pdb:1FQN|rcsb pdb:1FQR|rcsb pdb:1FR4|rcsb pdb:1FR7|rcsb pdb:1FSN|rcsb pdb:1FSQ|rcsb pdb:1FSR|rcsb pdb:1G0E|rcsb pdb:1G0F|rcsb pdb:1G1D|rcsb pdb:1G3Z|rcsb pdb:1G45|rcsb pdb:6OUD|rcsb pdb:6OUE|rcsb pdb:6OUF|rcsb pdb:6OUH|rcsb pdb:6OUI|rcsb pdb:6OUJ|rcsb pdb:6OUK|rcsb pdb:6OUM|rcsb pdb:6PDV|rcsb pdb:6PEA|rcsb pdb:6PGX|rcsb pdb:6Q3O|rcsb pdb:6Q9T|rcsb pdb:6QEB|rcsb pdb:6QL1|rcsb pdb:6QL2|rcsb pdb:6QL3|rcsb pdb:6OUB|rcsb pdb:6R6F|rcsb pdb:6R6J|rcsb pdb:6RFH|rcsb pdb:6RG3|rcsb pdb:6RG4|rcsb pdb:6RG5|rcsb pdb:6RH4|rcsb pdb:6RHJ|rcsb pdb:6RHK|rcsb pdb:6RIG|rcsb pdb:6RIT|rcsb pdb:6RJJ|rcsb pdb:6RKN|rcsb pdb:6RL9|rcsb pdb:6RM1|rcsb pdb:6RMP|rcsb pdb:6RMX|rcsb pdb:6RMY|rcsb pdb:6RNP|rcsb pdb:6ROB|rcsb pdb:6ROE|rcsb pdb:6ROF|rcsb pdb:3TVO|rcsb pdb:3U3A|rcsb pdb:3U45|rcsb pdb:3U47|rcsb pdb:3U7C|rcsb pdb:3V2J|rcsb pdb:3TVN|rcsb pdb:3V2M|rcsb pdb:3V3F|rcsb pdb:3V3G|rcsb pdb:3V3H|rcsb pdb:3V3I|rcsb pdb:3V3J|rcsb pdb:3V5G|rcsb pdb:3V7X|rcsb pdb:3VBD|rcsb pdb:3ZP9|rcsb pdb:4BCW|rcsb pdb:4BF1|rcsb pdb:4BF6|rcsb pdb:4CA2|rcsb pdb:4CAC|rcsb pdb:4CQ0|rcsb pdb:4DZ7|rcsb pdb:4DZ9|rcsb pdb:4E3D|rcsb pdb:6RQI|rcsb pdb:6T5C|rcsb pdb:6T7U|rcsb pdb:6T81|rcsb pdb:6T9Z|rcsb pdb:6U4Q|rcsb pdb:6U4T|rcsb pdb:6UFB|rcsb pdb:6UFC|rcsb pdb:6UFD|rcsb pdb:6UGN|rcsb pdb:6UGO|rcsb pdb:6UGP|rcsb pdb:6UGQ|rcsb pdb:6UGR|rcsb pdb:6UGZ|rcsb pdb:6UH0|rcsb pdb:6UX1|rcsb pdb:6UZU|rcsb pdb:6VJ3|rcsb pdb:6VKG|rcsb pdb:1TG3|rcsb pdb:1TG9|rcsb pdb:1TH9|rcsb pdb:1THK|rcsb pdb:1TTM|rcsb pdb:1UGA|rcsb pdb:1UGB|rcsb pdb:1UGC|rcsb pdb:1UGD|rcsb pdb:1UGE|rcsb pdb:1UGF|rcsb pdb:1UGG|rcsb pdb:1XEG|rcsb pdb:1XEV|rcsb pdb:1XPZ|rcsb pdb:1XQ0|rcsb pdb:1YDA|rcsb pdb:1YDB|rcsb pdb:1YDC|rcsb pdb:1YDD|rcsb pdb:1YO0|rcsb pdb:1YO1|rcsb pdb:1YO2|rcsb pdb:1Z9Y|rcsb pdb:1ZE8|rcsb pdb:1ZFK|rcsb pdb:1ZFQ|rcsb pdb:1ZGE|rcsb pdb:4E3F|rcsb pdb:4E3G|rcsb pdb:4E3H|rcsb pdb:4E49|rcsb pdb:4E4A|rcsb pdb:4E5Q|rcsb pdb:4FIK|rcsb pdb:4FL7|rcsb pdb:4FPT|rcsb pdb:4FRC|rcsb pdb:4FU5|rcsb pdb:4FVN|rcsb pdb:4FVO|rcsb pdb:4G0C|rcsb pdb:4GL1|rcsb pdb:4HBA|rcsb pdb:4HEW|rcsb pdb:4HEY|rcsb pdb:4HEZ|rcsb pdb:4HF3|rcsb pdb:4HT0|rcsb pdb:4IDR|rcsb pdb:4ILX|rcsb pdb:4ITO|rcsb pdb:4ITP|rcsb pdb:4IWZ|rcsb pdb:4JS6|rcsb pdb:4JSA|rcsb pdb:4JSS|rcsb pdb:4JSW|rcsb pdb:4JSZ|rcsb pdb:4K0S|rcsb pdb:4K0T|rcsb pdb:4K0Z|rcsb pdb:4K13|rcsb pdb:4K1Q|rcsb pdb:4KAP|rcsb pdb:4KNI|rcsb pdb:4KNJ|rcsb pdb:4KUV|rcsb pdb:4KUW|rcsb pdb:4KUY|rcsb pdb:4KV0|rcsb pdb:4L5U|rcsb pdb:4L5V|rcsb pdb:4L5W|rcsb pdb:4LHI|rcsb pdb:4LP6|rcsb pdb:4M2R|rcsb pdb:4M2U|rcsb pdb:4M2V|rcsb pdb:4M2W|rcsb pdb:4MDG|rcsb pdb:4MDL|rcsb pdb:4MDM|rcsb pdb:4MLT|rcsb pdb:4MLX|rcsb pdb:1ZGF|rcsb pdb:1ZH9|rcsb pdb:1ZSA|rcsb pdb:1ZSB|rcsb pdb:1ZSC|rcsb pdb:2ABE|rcsb pdb:2AW1|rcsb pdb:2AX2|rcsb pdb:2CA2|rcsb pdb:2CBA|rcsb pdb:2CBB|rcsb pdb:2CBC|rcsb pdb:2CBD|rcsb pdb:2CBE|rcsb pdb:2EU2|rcsb pdb:2EU3|rcsb pdb:2EZ7|rcsb pdb:2F14|rcsb pdb:2FMG|rcsb pdb:2FMZ|rcsb pdb:2FNK|rcsb pdb:2FNM|rcsb pdb:2FNN|rcsb pdb:2HOC|rcsb pdb:2FOQ|rcsb pdb:2FOS|rcsb pdb:2ILI|rcsb pdb:2FOU|rcsb pdb:2NNG|rcsb pdb:2NNO|rcsb pdb:2NNS|rcsb pdb:2FOV|rcsb pdb:2GD8|rcsb pdb:2GEH|rcsb pdb:2NNV|rcsb pdb:2NWO|rcsb pdb:2NWP|rcsb pdb:2NWY|rcsb pdb:2NWZ|rcsb pdb:2H15|rcsb pdb:2NXR|rcsb pdb:2NXS|rcsb pdb:2NXT|rcsb pdb:2O4Z|rcsb pdb:2OSF|rcsb pdb:2OSM|rcsb pdb:2POU|rcsb pdb:2POV|rcsb pdb:2POW|rcsb pdb:2H4N|rcsb pdb:2Q1B|rcsb pdb:2Q1Q|rcsb pdb:2Q38|rcsb pdb:2QO8|rcsb pdb:2QOA|rcsb pdb:2QP6|rcsb pdb:2VVA|rcsb pdb:2VVB|rcsb pdb:2HD6|rcsb pdb:2HKK|rcsb pdb:2WD2|rcsb pdb:2WD3|rcsb pdb:2HL4|rcsb pdb:2HNC|rcsb pdb:2WEG|rcsb pdb:2WEH|rcsb pdb:2WEJ|rcsb pdb:2WEO|rcsb pdb:4MTY|rcsb pdb:4N0X|rcsb pdb:4N16|rcsb pdb:4PQ7|rcsb pdb:4PXX|rcsb pdb:4PYX|rcsb pdb:4PYY|rcsb pdb:4PZH|rcsb pdb:4Q06|rcsb pdb:4Q07|rcsb pdb:4Q08|rcsb pdb:4Q09|rcsb pdb:4Q49|rcsb pdb:4Q6D|rcsb pdb:4Q6E|rcsb pdb:4Q78|rcsb pdb:4Q7P|rcsb pdb:4Q7S|rcsb pdb:4Q7V|rcsb pdb:4Q7W|rcsb pdb:4Q81|rcsb pdb:4Q83|rcsb pdb:4Q87|rcsb pdb:4Q8X|rcsb pdb:4Q8Y|rcsb pdb:4Q8Z|rcsb pdb:4Q90|rcsb pdb:4Q99|rcsb pdb:4Q9Y|rcsb pdb:4QEF|rcsb pdb:4QIY|rcsb pdb:4QJM|rcsb pdb:4QK1|rcsb pdb:4QK2|rcsb pdb:4QK3|rcsb pdb:4QSA|rcsb pdb:4QSB|rcsb pdb:4QSI|rcsb pdb:4QTL|rcsb pdb:4QY3|rcsb pdb:4R59|rcsb pdb:4R5A|rcsb pdb:4R5B|rcsb pdb:4RFC|rcsb pdb:4RFD|rcsb pdb:4RH2|rcsb pdb:4RIU|rcsb pdb:4RIV|rcsb pdb:4RN4|rcsb pdb:4RUX|rcsb pdb:4RUY|rcsb pdb:4RUZ|rcsb pdb:4WL4|rcsb pdb:4WW6|rcsb pdb:4MO8|rcsb pdb:4XE1|rcsb pdb:4Y0J|rcsb pdb:4YGJ|rcsb pdb:4YGK|rcsb pdb:4YGL|rcsb pdb:4YGN|rcsb pdb:4YVY|rcsb pdb:4YWP|rcsb pdb:4YX4|rcsb pdb:4YXI|rcsb pdb:4YXO|rcsb pdb:6RRI|rcsb pdb:6RS5|rcsb pdb:6RSZ|rcsb pdb:6RVF|rcsb pdb:6RVK|rcsb pdb:6RVL|rcsb pdb:6RW1|rcsb pdb:6RZX|rcsb pdb:6S03|rcsb pdb:6S9G|rcsb pdb:6S9Z|rcsb pdb:6SAC|rcsb pdb:6SAS|rcsb pdb:6SAY|rcsb pdb:6SB7|rcsb pdb:6SBH|rcsb pdb:6SBL|rcsb pdb:6SBM|rcsb pdb:6SD7|rcsb pdb:6SDH|rcsb pdb:6SDI|rcsb pdb:6SDJ|rcsb pdb:6SDL|rcsb pdb:6SDS|rcsb pdb:6SEY|rcsb pdb:6RRG|rcsb pdb:6SFQ|rcsb pdb:6SFU|rcsb pdb:6SG0|rcsb pdb:6SG6|rcsb pdb:6SX9|rcsb pdb:6SYB|rcsb pdb:6SYS|rcsb pdb:6T4N|rcsb pdb:6T4O|rcsb pdb:6T4P|rcsb pdb:2X7S|rcsb pdb:2X7T|rcsb pdb:2X7U|rcsb pdb:3B4F|rcsb pdb:3BET|rcsb pdb:3BL0|rcsb pdb:3BL1|rcsb pdb:3C7P|rcsb pdb:3CA2|rcsb pdb:3CAJ|rcsb pdb:3CYU|rcsb pdb:3D8W|rcsb pdb:3D92|rcsb pdb:3D93|rcsb pdb:3D9Z|rcsb pdb:3DAZ|rcsb pdb:3DBU|rcsb pdb:3DC3|rcsb pdb:3DC9|rcsb pdb:3DCC|rcsb pdb:3DCS|rcsb pdb:3DCW|rcsb pdb:3DD0|rcsb pdb:3DD8|rcsb pdb:3DV7|rcsb pdb:3DVB|rcsb pdb:3DVC|rcsb pdb:3DVD|rcsb pdb:3EFI|rcsb pdb:3EFT|rcsb pdb:4YYT|rcsb pdb:4Z0Q|rcsb pdb:4Z1E|rcsb pdb:4Z1J|rcsb pdb:4Z1K|rcsb pdb:4Z1N|rcsb pdb:4ZAO|rcsb pdb:4ZWI|rcsb pdb:4ZWX|rcsb pdb:4ZWY|rcsb pdb:4ZWZ|rcsb pdb:4ZX0|rcsb pdb:4ZX1|rcsb pdb:5A6H|rcsb pdb:5AMD|rcsb pdb:5AMG|rcsb pdb:5AML|rcsb pdb:5BNL|rcsb pdb:5BRU|rcsb pdb:5BRV|rcsb pdb:5BRW|rcsb pdb:5BYI|rcsb pdb:5C8I|rcsb pdb:5CA2|rcsb pdb:5CAC|rcsb pdb:5CLU|rcsb pdb:5DOG|rcsb pdb:5DOH|rcsb pdb:5DRS|rcsb pdb:5DSK|rcsb pdb:5DSL|rcsb pdb:5DSM|rcsb pdb:5DSO|rcsb pdb:5DSP|rcsb pdb:4YXU|rcsb pdb:5DSQ|rcsb pdb:5DSR|rcsb pdb:5E28|rcsb pdb:5E2K|rcsb pdb:5E2R|rcsb pdb:5E2S|rcsb pdb:5EH5|rcsb pdb:5EH7|rcsb pdb:5EH8|rcsb pdb:5EHE|rcsb pdb:5EHV|rcsb pdb:5EHW|rcsb pdb:5EIJ|rcsb pdb:5EKH|rcsb pdb:3F4X|rcsb pdb:3F8E|rcsb pdb:3FFP|rcsb pdb:3GZ0|rcsb pdb:3HFP|rcsb pdb:3HKN|rcsb pdb:3HKQ|rcsb pdb:3HKT|rcsb pdb:3HKU|rcsb pdb:3HLJ|rcsb pdb:3HS4|rcsb pdb:3IBI|rcsb pdb:3IBL|rcsb pdb:3IBN|rcsb pdb:3IBU|rcsb pdb:3IEO|rcsb pdb:3IGP|rcsb pdb:3K2F|rcsb pdb:3K34|rcsb pdb:3K7K|rcsb pdb:3KIG|rcsb pdb:3KKX|rcsb pdb:3KNE|rcsb pdb:3KOI|rcsb pdb:3KOK|rcsb pdb:3KON|rcsb pdb:3KS3|rcsb pdb:3KWA|rcsb pdb:3L14|rcsb pdb:3M04|rcsb pdb:3M14|rcsb pdb:3M1J|rcsb pdb:3M1K|rcsb pdb:3M1Q|rcsb pdb:3M1W|rcsb pdb:3M2N|rcsb pdb:3M2X|rcsb pdb:3M2Y|rcsb pdb:3M2Z|rcsb pdb:3M3X|rcsb pdb:3M40|rcsb pdb:3M5E|rcsb pdb:3M5S|rcsb pdb:3M5T|rcsb pdb:3M67|rcsb pdb:3M96|rcsb pdb:3M98|rcsb pdb:3MHC|rcsb pdb:3MHI|rcsb pdb:3MHL|rcsb pdb:3MHM|rcsb pdb:3MHO|rcsb pdb:3ML2|rcsb pdb:3MMF|rcsb pdb:3MNA|rcsb pdb:3MNH|rcsb pdb:3MNI|rcsb pdb:3MNJ|rcsb pdb:3MNK|rcsb pdb:3MNU|rcsb pdb:3MWO|rcsb pdb:3MYQ|rcsb pdb:3MZC|rcsb pdb:3N0N|rcsb pdb:3N2P|rcsb pdb:5EKM|rcsb pdb:5EOI|rcsb pdb:5FDC|rcsb pdb:5FDI|rcsb pdb:5FLO|rcsb pdb:5FLP|rcsb pdb:5FLQ|rcsb pdb:5FLR|rcsb pdb:5FLS|rcsb pdb:5FLT|rcsb pdb:5FNG|rcsb pdb:5FNH|rcsb pdb:5FNI|rcsb pdb:5FNJ|rcsb pdb:5FNK|rcsb pdb:5FNL|rcsb pdb:5FNM|rcsb pdb:5G01|rcsb pdb:5G03|rcsb pdb:5G0B|rcsb pdb:5G0C|rcsb pdb:5GMN|rcsb pdb:5J8Z|rcsb pdb:5EKJ|rcsb pdb:3N4B|rcsb pdb:3N3J|rcsb pdb:3NB5|rcsb pdb:3NI5|rcsb pdb:3NJ9|rcsb pdb:3OIK|rcsb pdb:3OIL|rcsb pdb:3OIM|rcsb pdb:3OKU|rcsb pdb:3OKV|rcsb pdb:3OY0|rcsb pdb:3OYQ|rcsb pdb:3OYS|rcsb pdb:3P3H|rcsb pdb:3P3J|rcsb pdb:3P44|rcsb pdb:3P4V|rcsb pdb:3P55|rcsb pdb:3P58|rcsb pdb:3P5A|rcsb pdb:3P5L|rcsb pdb:3PJJ|rcsb pdb:3PO6|rcsb pdb:5JE7|rcsb pdb:5JEG|rcsb pdb:5JEH|rcsb pdb:5JEP|rcsb pdb:5JES|rcsb pdb:5JG3|rcsb pdb:5JG5|rcsb pdb:5JGS|rcsb pdb:5JGT|rcsb pdb:5JMZ|rcsb pdb:5JN3|rcsb pdb:5JN7|rcsb pdb:5JQ0|rcsb pdb:5JQT|rcsb pdb:5L3O|rcsb pdb:5L6K|rcsb pdb:5L6T|rcsb pdb:5L70|rcsb pdb:5L9E|rcsb pdb:5JDV|rcsb pdb:5LJQ|rcsb pdb:5LJT|rcsb pdb:5LL4|rcsb pdb:5LL8|rcsb pdb:5LLC|rcsb pdb:5LLE|rcsb pdb:5LLG|rcsb pdb:5LLH|rcsb pdb:5LMD|rcsb pdb:5LVS|rcsb pdb:5M78|rcsb pdb:5MJN|rcsb pdb:5N0D|rcsb pdb:5N0E|rcsb pdb:5N1R|rcsb pdb:5N1S|rcsb pdb:5N24|rcsb pdb:5N25|rcsb pdb:5NEA|rcsb pdb:5NEE|rcsb pdb:5NXG|ensembl:ENSG00000104267(gene)|ensembl:ENST00000285379(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0004064"(arylesterase activity)|go:"GO:0004089"(carbonate dehydratase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009268"(response to pH)|go:"GO:0010043"(response to zinc ion)|go:"GO:0015670"(carbon dioxide transport)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016836"(hydro-lyase activity)|go:"GO:0030424"(axon)|go:"GO:0032849"(positive regulation of cellular pH reduction)|go:"GO:0038166"(angiotensin-activated signaling pathway)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043627"(response to estrogen)|go:"GO:0044070"(regulation of anion transport)|rcsb pdb:1G4O|rcsb pdb:1G52|rcsb pdb:1G53|rcsb pdb:1G54|rcsb pdb:1H4N|rcsb pdb:1H9N|rcsb pdb:1H9Q|rcsb pdb:1HCA|rcsb pdb:1G4J|rcsb pdb:1HEA|rcsb pdb:1HEB|rcsb pdb:1HEC|rcsb pdb:1HED|rcsb pdb:1HVA|rcsb pdb:1I8Z|rcsb pdb:1I90|rcsb pdb:1I91|rcsb pdb:1I9L|rcsb pdb:1I9M|rcsb pdb:1I9N|rcsb pdb:1I9O|rcsb pdb:1I9P|rcsb pdb:3QYK|rcsb pdb:3R16|rcsb pdb:3R17|rcsb pdb:3RG3|rcsb pdb:3RG4|rcsb pdb:3RGE|rcsb pdb:3RJ7|rcsb pdb:3RLD|rcsb pdb:3RYJ|rcsb pdb:3RYV|rcsb pdb:3RYX|rcsb pdb:3RYY|rcsb pdb:3RYZ|rcsb pdb:3RZ0|rcsb pdb:3RZ1|rcsb pdb:3PYK|rcsb pdb:3RZ5|rcsb pdb:3RZ7|rcsb pdb:3RZ8|rcsb pdb:3S71|rcsb pdb:3S72|rcsb pdb:3S73|rcsb pdb:3S74|rcsb pdb:3S75|rcsb pdb:3S76|rcsb pdb:3S77|rcsb pdb:3S78|rcsb pdb:3S8X|rcsb pdb:3S9T|rcsb pdb:3SAP|rcsb pdb:3SAX|rcsb pdb:3SBH|rcsb pdb:3SBI|rcsb pdb:3T5U|rcsb pdb:3T5Z|rcsb pdb:3T82|rcsb pdb:3T83|rcsb pdb:3T84|rcsb pdb:3T85|rcsb pdb:3TMJ|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:2001150"(positive regulation of dipeptide transmembrane transport)|interpro:IPR001148(Carbonic anhydrase, eukaryotic)|interpro:IPR018338|interpro:IPR023561|interpro:IPR036398|mint:P00918|rcsb pdb:12CA|rcsb pdb:1A42|rcsb pdb:1AM6|rcsb pdb:1AVN|rcsb pdb:1BCD|rcsb pdb:1BIC|rcsb pdb:1BN1|rcsb pdb:1BN3|rcsb pdb:1BN4|rcsb pdb:1BNM|rcsb pdb:1BNN|rcsb pdb:1BNQ|rcsb pdb:1BNT|rcsb pdb:1BNU|rcsb pdb:1BNV|rcsb pdb:5NXI|rcsb pdb:5NY3|rcsb pdb:5NY6|rcsb pdb:5NYA|rcsb pdb:5O07|rcsb pdb:5OGN|rcsb pdb:5OGO|rcsb pdb:5OGP|rcsb pdb:5SZ0|rcsb pdb:5SZ1|rcsb pdb:5SZ2|rcsb pdb:5NXM|rcsb pdb:5NXO|rcsb pdb:5SZ3|rcsb pdb:5SZ4|rcsb pdb:5SZ5|rcsb pdb:5SZ6|rcsb pdb:5NXP|rcsb pdb:5SZ7|rcsb pdb:5T71|rcsb pdb:5T72|rcsb pdb:5T74|rcsb pdb:5T75|rcsb pdb:5TFX|rcsb pdb:5TH4|rcsb pdb:5THI|rcsb pdb:5THJ|rcsb pdb:5THN|rcsb pdb:5TI0|rcsb pdb:5TXY|rcsb pdb:5TY1|rcsb pdb:5TY8|rcsb pdb:5TY9|rcsb pdb:5NXV|rcsb pdb:5NXW|rcsb pdb:5NY1|rcsb pdb:5TYA|rcsb pdb:5U0D|rcsb pdb:5U0E|rcsb pdb:5U0F|rcsb pdb:6WKA|rcsb pdb:6WQ4|rcsb pdb:6WQ5|rcsb pdb:6WQ7|rcsb pdb:6WQ8|rcsb pdb:6WQ9|rcsb pdb:6XVH|rcsb pdb:6XWZ|rcsb pdb:6XXT|rcsb pdb:6YH4|rcsb pdb:6YH5|rcsb pdb:6YH6|rcsb pdb:6YH7|rcsb pdb:6YH8|rcsb pdb:6YH9|rcsb pdb:6YHA|rcsb pdb:6YHB|rcsb pdb:6YHC|rcsb pdb:6YJ3|rcsb pdb:6YKC|rcsb pdb:6YKH|rcsb pdb:6YMA|rcsb pdb:6YMB|rcsb pdb:6YO2|rcsb pdb:6YO4|rcsb pdb:6YO7|rcsb pdb:6YOI|rcsb pdb:6YOK|rcsb pdb:6YOL|rcsb pdb:6YPW|rcsb pdb:6YQT|rcsb pdb:6YQU|rcsb pdb:6YRI|rcsb pdb:6YZJ|rcsb pdb:6YZK|rcsb pdb:6YZL|rcsb pdb:6YZT|rcsb pdb:6YZU|rcsb pdb:6YZV|rcsb pdb:6YZM|rcsb pdb:6YZW|rcsb pdb:6YZX|rcsb pdb:6Z04|rcsb pdb:6ZR8|rcsb pdb:6YZN|rcsb pdb:6YZO|rcsb pdb:7BI5|rcsb pdb:7CA2|rcsb pdb:7JNR|rcsb pdb:7JNV|rcsb pdb:7JNW|rcsb pdb:7JNX|rcsb pdb:7JNZ|rcsb pdb:7JO0|rcsb pdb:7JO1|rcsb pdb:7JO2|rcsb pdb:7JO3|rcsb pdb:7JOB|rcsb pdb:7JOC|rcsb pdb:7K6I|rcsb pdb:7K6J|rcsb pdb:7K6K|rcsb pdb:7K6L|rcsb pdb:7K6T|rcsb pdb:7K6U|rcsb pdb:7K6X|rcsb pdb:7K6Z|rcsb pdb:8CA2|rcsb pdb:9CA2|reactome:R-HSA-1237044|reactome:R-HSA-1247673|reactome:R-HSA-1475029|rcsb pdb:6YZP|rcsb pdb:6YZQ|rcsb pdb:6YZR|rcsb pdb:6YZS - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606 rogid:Er5rv/L2XS7uyrm/fPxFFsN+EsU9606 rigid:xeOafV2Ssbob1sUqXUO1IuOoquw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R0 uniprotkb:Q86YM7 intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710 intact:EBI-746815|uniprotkb:O96003|uniprotkb:Q86YM5|uniprotkb:B2R688|ensembl:ENSP00000334382 psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym) psi-mi:home1_human(display_long)|uniprotkb:HOMER1(gene name)|psi-mi:HOMER1(display_short)|uniprotkb:SYN47(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479978|imex:IM-26985-249 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886 refseq:NP_001264006.1|refseq:NP_001264007.1|refseq:NP_004263.1|go:"GO:0005886"(plasma membrane)|go:"GO:0007206"(phospholipase C-activating G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007216"(G protein-coupled glutamate receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0035256"(G protein-coupled glutamate receptor binding)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0043034"(costamere)|go:"GO:0043197"(dendritic spine)|go:"GO:0044309"(neuron spine)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0048148"(behavioral response to cocaine)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0048875"(chemical homeostasis within a tissue)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051928"(positive regulation of calcium ion transport)|go:"GO:0051966"(regulation of synaptic transmission, glutamatergic)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:2001257"(regulation of cation channel activity)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR044100|mint:Q86YM7|reactome:R-HSA-6794361|go:"GO:2001256"(regulation of store-operated calcium entry)|ensembl:ENSG00000152413(gene)|ensembl:ENST00000334082(transcript)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol) - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606 rogid:ZKKSd3cgSM6/8RKLxorPAHaudLA9606 rigid:xeOafV2Ssbob1sUqXUO1IuOoquw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R0 uniprotkb:Q13126 intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710 intact:EBI-2547776|ensembl:ENSP00000494373|uniprotkb:Q5T3P3|uniprotkb:Q9H010|uniprotkb:I2G7M5|uniprotkb:I2G7M6|uniprotkb:I2G7M7|uniprotkb:I2G7M8|uniprotkb:I2G7M9|uniprotkb:I2G7N0 psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym) psi-mi:mtap_human(display_long)|uniprotkb:MTAP(gene name)|psi-mi:MTAP(display_short)|uniprotkb:MSAP(gene name synonym)|uniprotkb:5'-methylthioadenosine phosphorylase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479978|imex:IM-26985-249 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886 ensembl:ENSG00000099810(gene)|ensembl:ENST00000644715(transcript)|go:"GO:0004645"(1,4-alpha-oligoglucan phosphorylase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0017061"(S-methyl-5-thioadenosine phosphorylase activity)|go:"GO:0019509"(L-methionine salvage from methylthioadenosine)|go:"GO:0032259"(methylation)|go:"GO:0033574"(response to testosterone)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:5EUB|rcsb pdb:5TC5|rcsb pdb:5TC6|rcsb pdb:5TC7|rcsb pdb:5TC8|rcsb pdb:6DYZ|rcsb pdb:6DZ0|rcsb pdb:6DZ2|rcsb pdb:6DZ3|reactome:R-HSA-1237112|reactome:R-HSA-8950505|interpro:IPR000845(Nucleoside phosphorylase)|interpro:IPR010044(Methylthioadenosine phosphorylase)|interpro:IPR018099|interpro:IPR035994|mint:Q13126|rcsb pdb:1CB0|rcsb pdb:1CG6|rcsb pdb:1K27|rcsb pdb:1SD1|rcsb pdb:1SD2|rcsb pdb:3LN5|rcsb pdb:3OZC|rcsb pdb:3OZD|rcsb pdb:3OZE|refseq:NP_002442.2 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606 rogid:YQYb6o+mNKPtlSdUKveEOo7fpHE9606 rigid:xeOafV2Ssbob1sUqXUO1IuOoquw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R0 uniprotkb:P27695 intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710 intact:EBI-1048805|uniprotkb:Q969L5|uniprotkb:Q99775|ensembl:ENSP00000216714|ensembl:ENSP00000381111|ensembl:ENSP00000451979 psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym) psi-mi:apex1_human(display_long)|uniprotkb:Apurinic-apyrimidinic endonuclease 1(gene name synonym)|uniprotkb:APEX nuclease(gene name synonym)|uniprotkb:APE1(gene name synonym)|uniprotkb:APEX1(gene name)|psi-mi:APEX1(display_short)|uniprotkb:APE(gene name synonym)|uniprotkb:APEX(gene name synonym)|uniprotkb:APX(gene name synonym)|uniprotkb:HAP1(gene name synonym)|uniprotkb:REF1(gene name synonym)|uniprotkb:REF-1(gene name synonym)|uniprotkb:Redox factor-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479978|imex:IM-26985-249 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886 refseq:NP_001632.2|refseq:NP_542379.1|refseq:NP_542380.1|refseq:NP_001231178.1|ensembl:ENSG00000100823(gene)|ensembl:ENST00000216714(transcript)|ensembl:ENST00000398030(transcript)|ensembl:ENST00000555414(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004519"(endonuclease activity)|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0004523"(RNA-DNA hybrid ribonuclease activity)|go:"GO:0004528"(phosphodiesterase I activity)|go:"GO:0004844"(uracil DNA N-glycosylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005840"(ribosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006310"(DNA recombination)|go:"GO:0007568"(aging)|go:"GO:0008081"(phosphoric diester hydrolase activity)|go:"GO:0008309"(double-stranded DNA exodeoxyribonuclease activity)|go:"GO:0008311"(double-stranded DNA 3'-5' exodeoxyribonuclease activity)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0016890"(site-specific endodeoxyribonuclease activity, specific for altered base)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0042493"|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0080111"(DNA demethylation)|go:"GO:0097698"(telomere maintenance via base-excision repair)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|interpro:IPR004808(Exodeoxyribonuclease III xth)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR020847|interpro:IPR020848|interpro:IPR036691|mint:P27695|rcsb pdb:1BIX|rcsb pdb:1CQG|rcsb pdb:1CQH|rcsb pdb:1DE8|rcsb pdb:1DE9|rcsb pdb:1DEW|rcsb pdb:1E9N|rcsb pdb:1HD7|rcsb pdb:2ISI|rcsb pdb:2O3H|rcsb pdb:3U8U|rcsb pdb:4IEM|rcsb pdb:4LND|rcsb pdb:4QH9|rcsb pdb:4QHD|rcsb pdb:4QHE|rcsb pdb:5CFG|rcsb pdb:5DFF|rcsb pdb:5DFH|rcsb pdb:5DFI|rcsb pdb:5DFJ|rcsb pdb:5DG0|rcsb pdb:5WN0|rcsb pdb:5WN1|rcsb pdb:5WN2|rcsb pdb:5WN3|rcsb pdb:5WN4|rcsb pdb:5WN5|rcsb pdb:6BOQ|rcsb pdb:6BOR|rcsb pdb:6BOS|rcsb pdb:6BOT|rcsb pdb:6BOU|rcsb pdb:6BOV|rcsb pdb:6BOW|rcsb pdb:6MK3|rcsb pdb:6MKK|rcsb pdb:6MKM|rcsb pdb:6MKO|rcsb pdb:6P93|rcsb pdb:6P94|rcsb pdb:6W0Q|rcsb pdb:6W2P|rcsb pdb:6W3L|rcsb pdb:6W3N|rcsb pdb:6W3Q|rcsb pdb:6W3U|rcsb pdb:6W43|rcsb pdb:6W4I|rcsb pdb:6W4T|reactome:R-HSA-110357|reactome:R-HSA-110362|reactome:R-HSA-110373|reactome:R-HSA-5651801|reactome:R-HSA-73930|reactome:R-HSA-73933|dip:DIP-6130N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606 rogid:418z7Qhlcop0UKIfNQse+iyM8gg9606 rigid:xeOafV2Ssbob1sUqXUO1IuOoquw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R0 uniprotkb:P23368 intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710 intact:EBI-1043318|uniprotkb:Q9H4B2|uniprotkb:Q9BYG1|ensembl:ENSP00000321070|uniprotkb:B2R8J2|uniprotkb:Q9BWL6 psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym) psi-mi:maom_human(display_long)|uniprotkb:Malic enzyme 2(gene name synonym)|uniprotkb:ME2(gene name)|psi-mi:ME2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479978|imex:IM-26985-249 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886 refseq:NP_001161807.1|rcsb pdb:1QR6|rcsb pdb:7BSJ|rcsb pdb:7BSK|rcsb pdb:7BSL|reactome:R-HSA-71403|ensembl:ENST00000321341(transcript)|go:"GO:0004470"(malic enzyme activity)|go:"GO:0004471"("malate dehydrogenase (decarboxylating) (NAD+) activity")|go:"GO:0004473"("malate dehydrogenase (decarboxylating) (NADP+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006108"(malate metabolic process)|ensembl:ENSG00000082212(gene)|go:"GO:0008948"(oxaloacetate decarboxylase activity)|go:"GO:0009055"(electron transfer activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0051287"(NAD binding)|go:"GO:1902031"(regulation of NADP metabolic process)|interpro:IPR001891(Malic oxidoreductase)|interpro:IPR012301(Malic enzyme, N-terminal)|interpro:IPR012302(Malic enzyme, NAD-binding)|interpro:IPR015884(Malic enzyme, conserved site)|interpro:IPR036291|interpro:IPR037062|mint:P23368|rcsb pdb:1DO8|rcsb pdb:1EFK|rcsb pdb:1EFL|rcsb pdb:1GZ3|rcsb pdb:1GZ4|rcsb pdb:1PJ2|rcsb pdb:1PJ3|rcsb pdb:1PJ4|rcsb pdb:1PJL|refseq:NP_002387.1 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606 rogid:aJAm/VMhqHLF07K3FlystextLrc9606 rigid:xeOafV2Ssbob1sUqXUO1IuOoquw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R0 uniprotkb:P63241 intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710 intact:EBI-373150|uniprotkb:P10159|uniprotkb:Q16182|uniprotkb:Q7L7L3|uniprotkb:Q7Z4L1|uniprotkb:Q9D0G2|uniprotkb:A8K9A0|uniprotkb:D3DTP2|ensembl:ENSP00000336776|ensembl:ENSP00000390677|ensembl:ENSP00000396073|ensembl:ENSP00000458269|ensembl:ENSP00000459196|ensembl:ENSP00000459611|ensembl:ENSP00000499855|ensembl:ENSP00000499995|ensembl:ENSP00000500414|ensembl:ENSP00000500624|ensembl:ENSP00000500717|ensembl:ENSP00000500847 psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym) psi-mi:if5a1_human(display_long)|uniprotkb:EIF5A(gene name)|psi-mi:EIF5A(display_short)|uniprotkb:Eukaryotic initiation factor 5A isoform 1(gene name synonym)|uniprotkb:eIF-4D(gene name synonym)|uniprotkb:Rev-binding factor(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479978|imex:IM-26985-249 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886 refseq:NP_001137232.1|refseq:NP_001137233.1|refseq:NP_001137234.1|refseq:NP_001961.1|refseq:XP_005256566.1|ensembl:ENSG00000132507(gene)|ensembl:ENSG00000288145(gene)|ensembl:ENST00000336458(transcript)|ensembl:ENST00000416016(transcript)|ensembl:ENST00000419711(transcript)|ensembl:ENST00000571955(transcript)|ensembl:ENST00000573542(transcript)|ensembl:ENST00000576930(transcript)|ensembl:ENST00000672250(transcript)|ensembl:ENST00000672755(transcript)|ensembl:ENST00000673099(transcript)|ensembl:ENST00000673210(transcript)|ensembl:ENST00000673259(transcript)|ensembl:ENST00000673304(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043022"(ribosome binding)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0045905"(positive regulation of translational termination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0098586"(cellular response to virus)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|interpro:IPR001884("Eukaryotic initiation factor 5A hypusine (eIF-5A)")|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR019769|interpro:IPR020189|mint:P63241|rcsb pdb:1FH4|rcsb pdb:3CPF|rcsb pdb:5DLQ|reactome:R-HSA-204626 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606 rogid:/smk81DLs+XvrqXmIZpfvdHHauk9606 rigid:xeOafV2Ssbob1sUqXUO1IuOoquw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R0 uniprotkb:A6NHR9 intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710 intact:EBI-2801919|uniprotkb:O75141|uniprotkb:Q6AHX6|uniprotkb:Q9H6Q2|uniprotkb:Q6ZTQ8|intact:EBI-3192385|uniprotkb:Q9UG39|ensembl:ENSP00000326603 psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym) psi-mi:smhd1_human(display_long)|uniprotkb:KIAA0650(gene name synonym)|uniprotkb:SMCHD1(gene name)|psi-mi:SMCHD1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479978|imex:IM-26985-249 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886 refseq:NP_056110.2|ensembl:ENSG00000101596(gene)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR036277|interpro:IPR036890|interpro:IPR038892|mint:A6NHR9|rcsb pdb:6MW7|ensembl:ENST00000320876(transcript)|go:"GO:0001740"(Barr body)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006302"(double-strand break repair)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043584"(nose development)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0060820"(inactivation of X chromosome by heterochromatin assembly)|go:"GO:0060821"(obsolete inactivation of X chromosome by DNA methylation) - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606 rogid:7tHwsz7p8pAqG9grnerpgMTmt3Q9606 rigid:xeOafV2Ssbob1sUqXUO1IuOoquw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R0 uniprotkb:P48735 intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710 intact:EBI-3931130|uniprotkb:Q96GT3|uniprotkb:B2R6L6|ensembl:ENSP00000331897|uniprotkb:B4DFL2 psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym) psi-mi:idhp_human(display_long)|uniprotkb:IDH2(gene name)|psi-mi:IDH2(display_short)|uniprotkb:ICD-M(gene name synonym)|uniprotkb:IDP(gene name synonym)|uniprotkb:"NADP(+)-specific ICDH"(gene name synonym)|uniprotkb:Oxalosuccinate decarboxylase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479978|imex:IM-26985-249 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886 ensembl:ENSG00000182054(gene)|ensembl:ENST00000330062(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004450"("isocitrate dehydrogenase (NADP+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006097"(glyoxylate cycle)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006739"(NADP metabolic process)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0051287"(NAD binding)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903976"(negative regulation of glial cell migration)|go:"GO:1904465"(negative regulation of matrix metallopeptidase secretion)|interpro:IPR004790(Isocitrate dehydrogenase NADP-dependent, eukaryotic)|interpro:IPR019818|interpro:IPR024084|mint:P48735|rcsb pdb:4JA8|rcsb pdb:5GIS|rcsb pdb:5I95|rcsb pdb:5I96|rcsb pdb:5SVN|rcsb pdb:5SVO|rcsb pdb:6ADI|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6VFZ|reactome:R-HSA-2151201|reactome:R-HSA-71403|refseq:NP_002159.2|refseq:NP_001276839.1|refseq:NP_001277043.1|dip:DIP-61416N - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606 rogid:CeuTM4HmOk3+OKkWlOt9JfNlCIM9606 rigid:xeOafV2Ssbob1sUqXUO1IuOoquw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R0 uniprotkb:P29692 intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710 intact:EBI-358607|uniprotkb:Q969J1|uniprotkb:D3DWK3|intact:EBI-748782|uniprotkb:Q96I38|ensembl:ENSP00000317399|ensembl:ENSP00000378551|ensembl:ENSP00000388261|ensembl:ENSP00000433412|ensembl:ENSP00000433611|ensembl:ENSP00000434448|ensembl:ENSP00000434872|ensembl:ENSP00000436542|ensembl:ENSP00000436933|ensembl:ENSP00000478340|ensembl:ENSP00000479653|ensembl:ENSP00000483527|ensembl:ENSP00000487680|intact:EBI-11048966|uniprotkb:Q4VBZ6|uniprotkb:B4DDU4|uniprotkb:E9PBQ9 psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym) psi-mi:ef1d_human(display_long)|uniprotkb:EEF1D(gene name)|psi-mi:EEF1D(display_short)|uniprotkb:EF1D(gene name synonym)|uniprotkb:Antigen NY-CO-4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479978|imex:IM-26985-249 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886 refseq:NP_001123528.1|refseq:NP_001123527.1|refseq:NP_001123529.1|refseq:NP_001951.2|refseq:XP_011515207.1|refseq:XP_011515208.1|ensembl:ENST00000419152(transcript)|ensembl:ENST00000529272(transcript)|ensembl:ENST00000530191(transcript)|ensembl:ENST00000530445(transcript)|ensembl:ENST00000531218(transcript)|ensembl:ENST00000533494(transcript)|ensembl:ENST00000534380(transcript)|ensembl:ENST00000614575(transcript)|ensembl:ENST00000615067(transcript)|ensembl:ENST00000615698(transcript)|ensembl:ENST00000632587(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0006414"(translational elongation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0009299"(mRNA transcription)|go:"GO:0010941"(regulation of cell death)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045296"(cadherin binding)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001326(Translation elongation factor EF1B, beta/delta chains, conserved site)|interpro:IPR014038(Translation elongation factor EF1B, beta and delta chains, guanine nucleotide exchange)|interpro:IPR014717(Translation elongation factor EF1B/ribosomal protein S6)|interpro:IPR018940|interpro:IPR036219|mint:P29692|rcsb pdb:2MVM|rcsb pdb:2MVN|rcsb pdb:2N51|rcsb pdb:5JPO|reactome:R-HSA-156842|ensembl:ENSG00000104529(gene)|ensembl:ENSG00000273594(gene)|ensembl:ENST00000317198(transcript)|ensembl:ENST00000395119(transcript)|refseq:NP_001304672.1|refseq:NP_001182132.1|refseq:NP_001276879.1|refseq:XP_006716585.1|refseq:XP_006716586.1|refseq:XP_006716587.1|refseq:XP_006716588.1|refseq:XP_005250880.1|refseq:NP_001317575.1|refseq:XP_016868659.1|refseq:NP_001123525.2|refseq:NP_115754.3 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606 rogid:9Mzpfofeg2W/GQ/JfjFxcCFJnKg9606 rigid:xeOafV2Ssbob1sUqXUO1IuOoquw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R0 uniprotkb:P54886 intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710 intact:EBI-1210304|ensembl:ENSP00000360268|uniprotkb:O95952|uniprotkb:Q5T566|uniprotkb:Q9UM72|uniprotkb:Q3KQU2|uniprotkb:B2R5Q4|uniprotkb:B7Z350|uniprotkb:B7Z5X8|uniprotkb:B7ZLP1|uniprotkb:Q5T567|uniprotkb:D3DR44 psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym) psi-mi:p5cs_human(display_long)|uniprotkb:ALDH18A1(gene name)|psi-mi:ALDH18A1(display_short)|uniprotkb:P5CS(gene name synonym)|uniprotkb:PYCS(gene name synonym)|uniprotkb:GSAS(gene name synonym)|uniprotkb:Aldehyde dehydrogenase family 18 member A1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479978|imex:IM-26985-249 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886 ensembl:ENSG00000059573(gene)|ensembl:ENST00000371224(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004349"(glutamate 5-kinase activity)|go:"GO:0004350"(glutamate-5-semialdehyde dehydrogenase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0006536"(glutamate metabolic process)|go:"GO:0006561"(proline biosynthetic process)|go:"GO:0006592"(ornithine biosynthetic process)|go:"GO:0019240"(citrulline biosynthetic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0055129"(L-proline biosynthetic process)|interpro:IPR000965(Gamma-glutamyl phosphate reductase GPR)|interpro:IPR001048(Aspartate/glutamate/uridylate kinase)|refseq:NP_001017423.1|refseq:NP_002851.2|refseq:NP_001310341.1|refseq:NP_001310342.1|refseq:NP_001310343.1|refseq:NP_001310344.1|refseq:NP_001310345.1|refseq:NP_001310348.1|interpro:IPR001057(Glutamate 5-kinase)|interpro:IPR005715(Glutamate 5-kinase, ProB-related)|interpro:IPR005766(delta l-pyrroline-5-carboxylate synthetase)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR019797|interpro:IPR020593|interpro:IPR036393|interpro:IPR041744|mint:P54886|rcsb pdb:2H5G|reactome:R-HSA-8964539 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606 rogid:NLYlqQhi3HebSXYBxkkSmKplRCM9606 rigid:xeOafV2Ssbob1sUqXUO1IuOoquw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R0 uniprotkb:P30042 intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710 intact:EBI-723904|uniprotkb:A6NFJ6|uniprotkb:A6NJY7|uniprotkb:O00650|uniprotkb:O00660|uniprotkb:O15011|uniprotkb:O15012|uniprotkb:P55346|uniprotkb:P78474|uniprotkb:Q92505|uniprotkb:Q92507|uniprotkb:P0DPI2 psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym) psi-mi:es1_human(display_long)|uniprotkb:Protein KNP-I(gene name synonym)|uniprotkb:Protein GT335(gene name synonym)|uniprotkb:C21orf33(gene name)|psi-mi:C21orf33(display_short)|uniprotkb:HES1(gene name synonym)|uniprotkb:KNPI(gene name synonym)|uniprotkb:GATD3A(gene name)|psi-mi:GATD3A(display_short)|uniprotkb:C21orf33(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479978|imex:IM-26985-249 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886 go:"GO:0005739"(mitochondrion)|refseq:NP_004640.4|refseq:NP_937798.4|refseq:XP_011507206.1|refseq:XP_011507208.1|interpro:IPR029062|ensembl:ENST00000291577|ensembl:ENST00000348499|refseq:XP_006723964.1|refseq:XP_006723966.1|ensembl:ENSG00000160221|ensembl:ENSP00000291577|ensembl:ENSP00000344901 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606 rogid:CV66j34bvaZ1sxNMzdW2acrkgZA9606 rigid:xeOafV2Ssbob1sUqXUO1IuOoquw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R0 uniprotkb:Q99798 intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710 intact:EBI-2932893|ensembl:ENSP00000216254|uniprotkb:O75809|uniprotkb:Q5JZ41|uniprotkb:Q6FHX0|uniprotkb:Q8TAQ6 psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym) psi-mi:acon_human(display_long)|uniprotkb:ACO2(gene name)|psi-mi:ACO2(display_short)|uniprotkb:Citrate hydro-lyase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479978|imex:IM-26985-249 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886 ensembl:ENSG00000100412(gene)|ensembl:ENST00000216254(transcript)|go:"GO:0001889"(liver development)|go:"GO:0003994"(aconitate hydratase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006101"(citrate metabolic process)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0035900"(response to isolation stress)|go:"GO:0047780"(citrate dehydratase activity)|go:"GO:0051538"(3 iron, 4 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR000573(Aconitase A/isopropylmalate dehydratase small subunit, swivel)|interpro:IPR001030(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha)|interpro:IPR006248(Aconitase, mitochondrial-like)|interpro:IPR015928(Aconitase/3-isopropylmalate dehydratase, swivel)|interpro:IPR015932(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2)|interpro:IPR018136|interpro:IPR036008|mint:Q99798|reactome:R-HSA-1268020|reactome:R-HSA-71403|interpro:IPR015931(Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomains 1 and 3)|refseq:NP_001089.1 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606 rogid:QpDlGJHSwqfCktMlwYXKTonXftA9606 rigid:xeOafV2Ssbob1sUqXUO1IuOoquw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R0 uniprotkb:Q9BS26 intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710 intact:EBI-541644|uniprotkb:O60319|uniprotkb:Q5VWZ7|uniprotkb:Q6UW14|uniprotkb:Q8WX67|intact:EBI-1054855|uniprotkb:Q4VXC1|ensembl:ENSP00000262455 psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym) psi-mi:erp44_human(display_long)|uniprotkb:ERP44(gene name)|psi-mi:ERP44(display_short)|uniprotkb:UNQ532/PRO1075(orf name)|uniprotkb:TXNDC4(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 4(gene name synonym)|uniprotkb:KIAA0573(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479978|imex:IM-26985-249 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886 ensembl:ENSG00000023318(gene)|ensembl:ENST00000262455(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0009986"(cell surface)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035580"(specific granule lumen)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR041862|interpro:IPR041870|mint:Q9BS26|rcsb pdb:2R2J|rcsb pdb:5GU6|rcsb pdb:5GU7|rcsb pdb:5HQP|rcsb pdb:5XWM|reactome:R-HSA-6798695|go:"GO:0009100"(glycoprotein metabolic process)|refseq:NP_055866.1 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606 rogid:TpwaFRifveb03iRPS2pEZve1kLA9606 rigid:xeOafV2Ssbob1sUqXUO1IuOoquw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R0 uniprotkb:Q9H2U2 intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710 intact:EBI-3957115|uniprotkb:B4DLP7|uniprotkb:Q4W5E9|uniprotkb:Q6PG51|uniprotkb:Q8TBW0|uniprotkb:Q96E55|uniprotkb:Q9H0T0|uniprotkb:Q9NX37|uniprotkb:Q9P033|uniprotkb:Q9ULX0|uniprotkb:I6L9B6|uniprotkb:F8WDN9|ensembl:ENSP00000343885 psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym) psi-mi:ipyr2_human(display_long)|uniprotkb:PPA2(gene name)|psi-mi:PPA2(display_short)|uniprotkb:Pyrophosphatase SID6-306(gene name synonym)|uniprotkb:Pyrophosphate phospho-hydrolase 2(gene name synonym)|uniprotkb:HSPC124(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479978|imex:IM-26985-249 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886 refseq:NP_008834.3|refseq:NP_789842.2|refseq:NP_789843.2|refseq:NP_789845.1|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0071344"(diphosphate metabolic process)|interpro:IPR008162(Inorganic pyrophosphatase)|interpro:IPR036649|mint:Q9H2U2|reactome:R-HSA-379726|reactome:R-HSA-71737|ensembl:ENSG00000138777(gene)|ensembl:ENST00000341695(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004427"(inorganic diphosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol) - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606 rogid:KrPc55Mf6MjN5tgxFagI03miOwY9606 rigid:xeOafV2Ssbob1sUqXUO1IuOoquw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R0 uniprotkb:Q12874 intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710 intact:EBI-1051880|uniprotkb:Q15460|uniprotkb:Q5VT87|uniprotkb:D3DPT5|ensembl:ENSP00000362110 psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym) psi-mi:sf3a3_human(display_long)|uniprotkb:Spliceosome-associated protein 61(gene name synonym)|uniprotkb:SF3a60(gene name synonym)|uniprotkb:SF3A3(gene name)|psi-mi:SF3A3(display_short)|uniprotkb:SAP61(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479978|imex:IM-26985-249 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886 refseq:NP_006793.1|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1903241"(U2-type prespliceosome assembly)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR021966|interpro:IPR024598|interpro:IPR031774|interpro:IPR031776|mint:Q12874|rcsb pdb:2DT7|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|go:"GO:0000389"(mRNA 3'-splice site recognition)|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|reactome:R-HSA-72163|rcsb pdb:6Y53|ensembl:ENSG00000183431(gene)|ensembl:ENST00000373019(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|dip:DIP-882N - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606 rogid:fNjNguUOXqApr46rOAEpTs2geqY9606 rigid:xeOafV2Ssbob1sUqXUO1IuOoquw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R0 uniprotkb:Q13642 intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710 intact:EBI-912547|intact:EBI-1052757|uniprotkb:B7Z5T4|uniprotkb:B7Z793|uniprotkb:O95212|uniprotkb:Q13230|uniprotkb:Q13645|uniprotkb:Q5JXI7|uniprotkb:Q5M7Y6|uniprotkb:Q6IB30|uniprotkb:Q9NZ40|uniprotkb:Q9UKZ8|uniprotkb:Q9Y630|ensembl:ENSP00000377710|ensembl:ENSP00000498684 psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym) psi-mi:fhl1_human(display_long)|uniprotkb:FHL1(gene name)|psi-mi:FHL1(display_short)|uniprotkb:SLIM1(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479978|imex:IM-26985-249 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886 refseq:XP_006724807.1|refseq:XP_006724808.1|refseq:XP_006724809.1|refseq:XP_006724810.1|refseq:NP_001153172.1|refseq:NP_001153176.1|refseq:NP_001161291.1|refseq:NP_001440.2|refseq:NP_001153171.1|refseq:NP_001153173.1|refseq:NP_001153174.1|refseq:NP_001153175.1|refseq:XP_016884846.1|ensembl:ENSG00000022267(gene)|ensembl:ENST00000394155(transcript)|ensembl:ENST00000651089(transcript)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR042997|mint:Q13642|rcsb pdb:1X63|rcsb pdb:2CUP|rcsb pdb:2CUR|rcsb pdb:2EGQ - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606 rogid:KZpPO3Pymj2oTCtX1//adbOZH+Y9606 rigid:xeOafV2Ssbob1sUqXUO1IuOoquw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R0 uniprotkb:P00491 intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710 intact:EBI-712238|ensembl:ENSP00000354532|uniprotkb:Q15160|uniprotkb:Q5PZ03|uniprotkb:B2R8S5|uniprotkb:D3DS00 psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym) psi-mi:pnph_human(display_long)|uniprotkb:Inosine phosphorylase(gene name synonym)|uniprotkb:PNP(gene name)|psi-mi:PNP(display_short)|uniprotkb:NP(gene name synonym)|uniprotkb:Inosine-guanosine phosphorylase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479978|imex:IM-26985-249 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886 go:"GO:0001882"(nucleoside binding)|go:"GO:0002060"(purine nucleobase binding)|go:"GO:0004731"(purine-nucleoside phosphorylase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006148"(inosine catabolic process)|go:"GO:0006149"(deoxyinosine catabolic process)|go:"GO:0006157"(deoxyadenosine catabolic process)|go:"GO:0006166"(purine ribonucleoside salvage)|go:"GO:0006204"(IMP catabolic process)|go:"GO:0006738"(nicotinamide riboside catabolic process)|go:"GO:0006955"(immune response)|go:"GO:0009165"(nucleotide biosynthetic process)|go:"GO:0019428"(allantoin biosynthetic process)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034418"(urate biosynthetic process)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043101"(purine-containing compound salvage)|go:"GO:0046059"(dAMP catabolic process)|go:"GO:0046638"(positive regulation of alpha-beta T cell differentiation)|go:"GO:0047975"(guanosine phosphorylase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000845(Nucleoside phosphorylase)|interpro:IPR011268(Inosine guanosine and xanthosine phosphorylase)|interpro:IPR011270(Purine nucleoside phosphorylase I, inosine and guanosine-specific)|interpro:IPR018099|interpro:IPR035994|mint:P00491|rcsb pdb:1M73|rcsb pdb:1PF7|rcsb pdb:1PWY|rcsb pdb:1RCT|rcsb pdb:1RFG|rcsb pdb:1RR6|rcsb pdb:1RSZ|rcsb pdb:1RT9|rcsb pdb:1ULA|rcsb pdb:1ULB|rcsb pdb:1V2H|rcsb pdb:1V3Q|rcsb pdb:1V41|rcsb pdb:1V45|rcsb pdb:1YRY|rcsb pdb:2A0W|rcsb pdb:2A0X|rcsb pdb:2A0Y|rcsb pdb:2OC4|rcsb pdb:2OC9|rcsb pdb:2ON6|rcsb pdb:2Q7O|rcsb pdb:3BGS|rcsb pdb:3D1V|rcsb pdb:3GB9|rcsb pdb:3GGS|ensembl:ENSG00000198805(gene)|ensembl:ENST00000361505(transcript)|go:"GO:0000255"(allantoin metabolic process)|rcsb pdb:3K8O|rcsb pdb:3K8Q|rcsb pdb:3PHB|rcsb pdb:4EAR|rcsb pdb:3INY|rcsb pdb:4EB8|rcsb pdb:4ECE|rcsb pdb:4GKA|rcsb pdb:5ETJ|rcsb pdb:5UGF|reactome:R-HSA-6798695|reactome:R-HSA-74217|reactome:R-HSA-74259|refseq:NP_000261.2|dip:DIP-50406N - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606 rogid:FOpaxV/M6HIA+THugPZDfN1ej1o9606 rigid:xeOafV2Ssbob1sUqXUO1IuOoquw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R0 uniprotkb:Q15459 intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710 intact:EBI-1054743|uniprotkb:E9PAW1|ensembl:ENSP00000215793 psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym) psi-mi:sf3a1_human(display_long)|uniprotkb:Spliceosome-associated protein 114(gene name synonym)|uniprotkb:SF3a120(gene name synonym)|uniprotkb:SF3A1(gene name)|psi-mi:SF3A1(display_short)|uniprotkb:SAP114(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479978|imex:IM-26985-249 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886 refseq:NP_005868.1|ensembl:ENSG00000099995(gene)|ensembl:ENST00000215793(transcript)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|rcsb pdb:2DT6|go:"GO:0071004"(U2-type prespliceosome)|rcsb pdb:2DT7|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6QX9|go:"GO:0071005"(U2-type precatalytic spliceosome)|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABI|reactome:R-HSA-72163|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1903241"(U2-type prespliceosome assembly)|interpro:IPR000061(SWAP/Surp)|interpro:IPR000626(Ubiquitin)|interpro:IPR022030|interpro:IPR029071|interpro:IPR035563|interpro:IPR035967|mint:Q15459|rcsb pdb:1ZKH|dip:DIP-29164N - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606 rogid:YrIs3RwfjUcDsHCJDgTLMnOUJZM9606 rigid:xeOafV2Ssbob1sUqXUO1IuOoquw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R0 uniprotkb:P62888 intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710 intact:EBI-353116|uniprotkb:P04645|uniprotkb:Q502Z6|ensembl:ENSP00000287038|ensembl:ENSP00000428085|uniprotkb:B2R591 psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym) psi-mi:rl30_human(display_long)|uniprotkb:RPL30(gene name)|psi-mi:RPL30(display_short)|uniprotkb:Large ribosomal subunit protein eL30(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479978|imex:IM-26985-249 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886 ensembl:ENSG00000156482(gene)|ensembl:ENST00000287038(transcript)|ensembl:ENST00000521291(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000231(Ribosomal protein L30e)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR022991|interpro:IPR029064|interpro:IPR039109|mint:P62888|rcsb pdb:3VI6|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_000980.1 - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606 rogid:xR9LwYg6N7m9njT1pYumOPKZVu49606 rigid:xeOafV2Ssbob1sUqXUO1IuOoquw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R0 uniprotkb:P56537 intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710 intact:EBI-372243|uniprotkb:Q6IBN8|uniprotkb:Q96TD5|uniprotkb:B7ZBG9|ensembl:ENSP00000363559|ensembl:ENSP00000363574|ensembl:ENSP00000502429 psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym) psi-mi:if6_human(display_long)|uniprotkb:EIF6(gene name)|psi-mi:EIF6(display_short)|uniprotkb:ITGB4BP(gene name synonym)|uniprotkb:OK/SW-cl.27(orf name)|uniprotkb:B4 integrin interactor(gene name synonym)|uniprotkb:CAB(gene name synonym)|uniprotkb:"p27(BBP)"(gene name synonym)|uniprotkb:"B(2)GCN homolog"(gene name synonym)|uniprotkb:EIF3A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479978|imex:IM-26985-249 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886 refseq:NP_002203.1|refseq:NP_852131.1|refseq:NP_852133.1|refseq:NP_001254739.1|ensembl:ENSG00000242372(gene)|ensembl:ENST00000374436(transcript)|ensembl:ENST00000374450(transcript)|ensembl:ENST00000675032(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005638"(lamin filament)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0032868"(response to insulin)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0042304"(regulation of fatty acid biosynthetic process)|go:"GO:0043022"(ribosome binding)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902626"(assembly of large subunit precursor of preribosome)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR002769(Translation initiation factor IF6)|mint:P56537|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8 - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606 rogid:A0pOylQptNBlSiBKiZre7INejF49606 rigid:xeOafV2Ssbob1sUqXUO1IuOoquw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R0 uniprotkb:P23526 intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710 intact:EBI-1053240|uniprotkb:Q96A36|ensembl:ENSP00000217426|uniprotkb:B3KUN3|uniprotkb:F5H737|uniprotkb:A8K307|uniprotkb:E1P5P2 psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym) psi-mi:sahh_human(display_long)|uniprotkb:S-adenosyl-L-homocysteine hydrolase(gene name synonym)|uniprotkb:AHCY(gene name)|psi-mi:AHCY(display_short)|uniprotkb:SAHH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479978|imex:IM-26985-249 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886 refseq:NP_000678.1|refseq:NP_001155238.1|ensembl:ENSG00000101444(gene)|ensembl:ENST00000217426(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002439"(chronic inflammatory response to antigenic stimulus)|go:"GO:0004013"(adenosylhomocysteinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0019510"(S-adenosylhomocysteine catabolic process)|go:"GO:0030554"(adenyl nucleotide binding)|go:"GO:0033353"(S-adenosylmethionine cycle)|go:"GO:0042470"(melanosome)|go:"GO:0042745"(circadian sleep/wake cycle)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000043(S-adenosyl-L-homocysteine hydrolase)|interpro:IPR015878(S-adenosyl-L-homocysteine hydrolase, NAD binding)|interpro:IPR020082|interpro:IPR036291|interpro:IPR042172|mint:P23526|rcsb pdb:1A7A|rcsb pdb:1LI4|refseq:XP_011526961.1|refseq:XP_005260374.1|refseq:NP_001309013.1|refseq:NP_001309014.1|rcsb pdb:3NJ4|rcsb pdb:4PFJ|rcsb pdb:4PGF|rcsb pdb:4YVF|rcsb pdb:5W49|rcsb pdb:5W4B|reactome:R-HSA-156581|reactome:R-HSA-1614635|reactome:R-HSA-2408508|reactome:R-HSA-5578997|refseq:XP_016883197.1|refseq:XP_016883198.1|dip:DIP-50557N - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606 rogid:+y7rwgw9EIMaVrkt4/9kbZM44sg9606 rigid:xeOafV2Ssbob1sUqXUO1IuOoquw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R0 uniprotkb:P24534 intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710 intact:EBI-354334|uniprotkb:Q6IBH9|uniprotkb:A8K795|ensembl:ENSP00000236957|ensembl:ENSP00000376055|ensembl:ENSP00000376056|ensembl:ENSP00000489993|ensembl:ENSP00000490214|ensembl:ENSP00000490326 psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym) psi-mi:ef1b_human(display_long)|uniprotkb:EEF1B(gene name synonym)|uniprotkb:EF1B(gene name synonym)|uniprotkb:EEF1B2(gene name)|psi-mi:EEF1B2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479978|imex:IM-26985-249 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886 refseq:NP_001032752.1|refseq:NP_001950.1|refseq:NP_066944.1|ensembl:ENSG00000114942(gene)|ensembl:ENSG00000283391(gene)|ensembl:ENST00000236957(transcript)|ensembl:ENST00000392221(transcript)|ensembl:ENST00000392222(transcript)|ensembl:ENST00000635728(transcript)|ensembl:ENST00000636275(transcript)|ensembl:ENST00000637253(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0006414"(translational elongation)|go:"GO:0045471"(response to ethanol)|interpro:IPR001326(Translation elongation factor EF1B, beta/delta chains, conserved site)|interpro:IPR014038(Translation elongation factor EF1B, beta and delta chains, guanine nucleotide exchange)|interpro:IPR014717(Translation elongation factor EF1B/ribosomal protein S6)|interpro:IPR018940|interpro:IPR036219|interpro:IPR036282|mint:P24534|rcsb pdb:1B64|rcsb pdb:5DQS|reactome:R-HSA-156842 - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606 rogid:d4zkwQOMlpr6XBapMfT1sxy2ZPs9606 rigid:xeOafV2Ssbob1sUqXUO1IuOoquw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R0 uniprotkb:P22392 intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710 intact:EBI-713693|ensembl:ENSP00000376886|ensembl:ENSP00000421064|ensembl:ENSP00000425581|ensembl:ENSP00000426901|ensembl:ENSP00000426976|uniprotkb:A8MWA3|uniprotkb:Q1WM23|uniprotkb:Q6LCT6 psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym) psi-mi:ndkb_human(display_long)|uniprotkb:nm23-H2(gene name synonym)|uniprotkb:C-myc purine-binding transcription factor PUF(gene name synonym)|uniprotkb:NME2(gene name)|psi-mi:NME2(display_short)|uniprotkb:NM23B(gene name synonym)|uniprotkb:Histidine protein kinase NDKB(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479978|imex:IM-26985-249 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886 ensembl:ENSG00000243678(gene)|ensembl:ENST00000393190(transcript)|ensembl:ENST00000503064(transcript)|ensembl:ENST00000512737(transcript)|ensembl:ENST00000513177(transcript)|ensembl:ENST00000514264(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002762"(negative regulation of myeloid leukocyte differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0004673"(protein histidine kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|refseq:NP_001018146.1|refseq:NP_001018147.1|refseq:NP_001018148.1|refseq:NP_001018149.1|refseq:NP_002503.1|dip:DIP-50179N|go:"GO:0005882"(intermediate filament)|go:"GO:0006165"(nucleoside diphosphate phosphorylation)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0007155"(cell adhesion)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009142"(nucleoside triphosphate biosynthetic process)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0060416"(response to growth hormone)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071944"(cell periphery)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|interpro:IPR023005|interpro:IPR034907|interpro:IPR036850|mint:P22392|rcsb pdb:1NSK|rcsb pdb:1NUE|rcsb pdb:3BBB|rcsb pdb:3BBC|rcsb pdb:3BBF|reactome:R-HSA-499943|reactome:R-HSA-6798695|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0019003"(GDP binding)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045682"(regulation of epidermis development)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm) - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606 rogid:GHHfoXOuc25KIJJqiW9r+OWm5Kk9606 rigid:xeOafV2Ssbob1sUqXUO1IuOoquw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R0 uniprotkb:P34897 intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710 intact:EBI-352908|ensembl:ENSP00000333667|uniprotkb:O00740|uniprotkb:Q8N1A5|uniprotkb:B7Z9F1|uniprotkb:E7EQ19|uniprotkb:E7EU43 psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym) psi-mi:glym_human(display_long)|uniprotkb:SHMT2(gene name)|psi-mi:SHMT2(display_short)|uniprotkb:Glycine hydroxymethyltransferase(gene name synonym)|uniprotkb:Serine methylase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479978|imex:IM-26985-249 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886 ensembl:ENSG00000182199(gene)|ensembl:ENST00000328923(transcript)|go:"GO:0000900"(translation repressor activity, mRNA regulatory element binding)|go:"GO:0002082"(regulation of oxidative phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0004372"(glycine hydroxymethyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006544"(glycine metabolic process)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0006565"(L-serine catabolic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008732"(L-allo-threonine aldolase activity)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019264"(glycine biosynthetic process from serine)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0034340"(response to type I interferon)|go:"GO:0035999"(tetrahydrofolate interconversion)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046653"(tetrahydrofolate metabolic process)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0050897"(cobalt ion binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070129"(regulation of mitochondrial translation)|go:"GO:0046655"(folic acid metabolic process)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0070552"(BRISC complex)|go:"GO:0070905"(serine binding)|go:"GO:1903715"(regulation of aerobic respiration)|interpro:IPR001085(Glycine hydroxymethyltransferase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|interpro:IPR019798|interpro:IPR039429|mint:P34897|rcsb pdb:4PVF|rcsb pdb:5V7I|rcsb pdb:5X3V|rcsb pdb:6DK3|rcsb pdb:6H3C|rcsb pdb:6M5O|rcsb pdb:6QVG|rcsb pdb:6QVL|rcsb pdb:6R8F|reactome:R-HSA-196757|reactome:R-HSA-9013408|refseq:NP_001159829.1|refseq:NP_001159830.1|refseq:NP_001159831.1|refseq:NP_005403.2|refseq:NP_001159828.1 - - comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606 rogid:Ce7izVDbUDULaGUe2fZWlikUZFk9606 rigid:xeOafV2Ssbob1sUqXUO1IuOoquw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H3R0 uniprotkb:P62633 intact:EBI-5277069|uniprotkb:B7ZL46|uniprotkb:O94877|uniprotkb:Q2M3M0|uniprotkb:Q5JUC9|uniprotkb:Q5VYJ2|uniprotkb:Q5VYJ3|uniprotkb:F5H7P0|uniprotkb:B4E1Y4|uniprotkb:F5H347|ensembl:ENSP00000370710 intact:EBI-1047529|uniprotkb:D3DNB9|uniprotkb:D3DNC0|uniprotkb:D3DNC1|uniprotkb:P20694|uniprotkb:Q5QJR0|uniprotkb:Q6PJI7|uniprotkb:Q96NV3|uniprotkb:B4DP17|uniprotkb:Q4JGY1|uniprotkb:B2RAV9|uniprotkb:Q4JGY0|uniprotkb:Q5U0E9|ensembl:ENSP00000410619|uniprotkb:A8K7V4|uniprotkb:E9PDR7 psi-mi:kdm4c_human(display_long)|uniprotkb:KDM4C(gene name)|psi-mi:KDM4C(display_short)|uniprotkb:GASC1(gene name synonym)|uniprotkb:JHDM3C(gene name synonym)|uniprotkb:JMJD2C(gene name synonym)|uniprotkb:KIAA0780(gene name synonym)|uniprotkb:Gene amplified in squamous cell carcinoma 1 protein(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3C(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4C"(gene name synonym) psi-mi:cnbp_human(display_long)|uniprotkb:Zinc finger protein 9(gene name synonym)|uniprotkb:CNBP(gene name)|psi-mi:CNBP(display_short)|uniprotkb:ZNF9(gene name synonym)|uniprotkb:RNF163(gene name synonym)|uniprotkb:Cellular nucleic acid-binding protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479978|imex:IM-26985-249 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140167.1|refseq:NP_001140168.1|refseq:NP_055876.2|dip:DIP-60098N|ensembl:ENSG00000107077(gene)|ensembl:ENST00000381309(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:Q9H3R0|rcsb pdb:2XDP|rcsb pdb:2XML|rcsb pdb:4XDO|rcsb pdb:4XDP|rcsb pdb:5FJH|rcsb pdb:5FJK|rcsb pdb:5KR7|reactome:R-HSA-3214842|reactome:R-HSA-5625886 refseq:NP_001120664.1|refseq:NP_001120668.1|refseq:NP_003409.1|refseq:NP_001120665.1|refseq:NP_001120666.1|ensembl:ENSG00000169714(gene)|ensembl:ENST00000422453(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0071919"(G-quadruplex DNA formation)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875|mint:P62633|refseq:NP_001120667.1 - - comment:"author score: 37" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lcR5fUu8oqzfIZxKafgsGUYXpOY9606 rogid:x5yqfxy/s3fE/6EmvjrEe7PmanQ9606 rigid:xeOafV2Ssbob1sUqXUO1IuOoquw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75164 uniprotkb:P81605 intact:EBI-936709|uniprotkb:Q5VVB1|ensembl:ENSP00000361473 intact:EBI-395625|uniprotkb:P58461|uniprotkb:A5JHP2|uniprotkb:A5JHP3|uniprotkb:Q53YJ2|ensembl:ENSP00000293371 psi-mi:kdm4a_human(display_long)|uniprotkb:KDM4A(gene name)|psi-mi:KDM4A(display_short)|uniprotkb:JMJD2(gene name synonym)|uniprotkb:KIAA0677(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2A(gene name synonym)|uniprotkb:JHDM3A(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(36) demethylase 4A"(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4A"(gene name synonym)|uniprotkb:JMJD2A(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3A(gene name synonym) psi-mi:dcd_human(display_long)|uniprotkb:AIDD(gene name synonym)|uniprotkb:DSEP(gene name synonym)|uniprotkb:Preproteolysin(gene name synonym)|uniprotkb:DCD(gene name)|psi-mi:DCD(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479882|imex:IM-26985-331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055478.2|refseq:XP_005271411.1|refseq:XP_005271412.1|dip:DIP-29372N|ensembl:ENSG00000066135(gene)|ensembl:ENST00000372396(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016577"(histone demethylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:O75164|rcsb pdb:2GF7|rcsb pdb:2GFA|rcsb pdb:2GP3|rcsb pdb:2GP5|rcsb pdb:2OQ6|rcsb pdb:2OQ7|rcsb pdb:2OS2|rcsb pdb:2OT7|rcsb pdb:2OX0|rcsb pdb:2P5B|rcsb pdb:2PXJ|rcsb pdb:2Q8C|rcsb pdb:2Q8D|rcsb pdb:2Q8E|rcsb pdb:2QQR|rcsb pdb:2QQS|rcsb pdb:2VD7|rcsb pdb:2WWJ|rcsb pdb:2YBK|rcsb pdb:2YBP|rcsb pdb:2YBS|rcsb pdb:3NJY|rcsb pdb:3PDQ|rcsb pdb:3RVH|rcsb pdb:3U4S|rcsb pdb:4AI9|rcsb pdb:4BIS|rcsb pdb:4GD4|rcsb pdb:4URA|rcsb pdb:4V2V|rcsb pdb:4V2W|rcsb pdb:5A7N|rcsb pdb:5A7O|rcsb pdb:5A7P|rcsb pdb:5A7Q|rcsb pdb:5A7S|rcsb pdb:5A7W|rcsb pdb:5A80|rcsb pdb:5ANQ|rcsb pdb:5D6W|rcsb pdb:5D6X|rcsb pdb:5D6Y|rcsb pdb:5F2S|rcsb pdb:5F2W|rcsb pdb:5F32|rcsb pdb:5F37|rcsb pdb:5F39|rcsb pdb:5F3C|rcsb pdb:5F3E|rcsb pdb:5F3G|rcsb pdb:5F3I|rcsb pdb:5F5I|rcsb pdb:5FPV|rcsb pdb:5FWE|rcsb pdb:5FY8|rcsb pdb:5FYC|rcsb pdb:5FYH|rcsb pdb:5FYI|rcsb pdb:5LY1|rcsb pdb:5LY2|rcsb pdb:5TVR|rcsb pdb:5TVS|rcsb pdb:5VAR|rcsb pdb:5VGI|rcsb pdb:5VMP|rcsb pdb:6CG1|rcsb pdb:6CG2|rcsb pdb:6G5W|rcsb pdb:6G5X|rcsb pdb:6H4O|rcsb pdb:6H4P|rcsb pdb:6H4Q|rcsb pdb:6H4R|rcsb pdb:6H4S|rcsb pdb:6H4T|rcsb pdb:6H4U|rcsb pdb:6H4V|rcsb pdb:6H4W|rcsb pdb:6H4X|rcsb pdb:6H4Y|rcsb pdb:6H8P|rcsb pdb:6HGT|rcsb pdb:7D4A|reactome:R-HSA-3214842|reactome:R-HSA-5693565|reactome:R-HSA-9029569 refseq:NP_444513.1|refseq:NP_001287783.1|ensembl:ENSG00000161634(gene)|ensembl:ENST00000293371(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008233"(peptidase activity)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR028130|interpro:IPR043557|mint:P81605|rcsb pdb:2KSG|rcsb pdb:2NDK|rcsb pdb:2YMK|rcsb pdb:6SHK|reactome:R-HSA-6803157 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:P8atv/4zKIc7bVg3IZYlw5gVIHY9606 rogid:M8PkKVWx98nhtd79ods05mqw8Ls9606 rigid:mjFSsqMcLkXX1ecO3bZymOEf+cw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75164 uniprotkb:P68363 intact:EBI-936709|uniprotkb:Q5VVB1|ensembl:ENSP00000361473 intact:EBI-487083|intact:EBI-1384226|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:Q27I68|ensembl:ENSP00000336799|uniprotkb:Q8WU19 psi-mi:kdm4a_human(display_long)|uniprotkb:KDM4A(gene name)|psi-mi:KDM4A(display_short)|uniprotkb:JMJD2(gene name synonym)|uniprotkb:KIAA0677(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2A(gene name synonym)|uniprotkb:JHDM3A(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(36) demethylase 4A"(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4A"(gene name synonym)|uniprotkb:JMJD2A(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3A(gene name synonym) psi-mi:tba1b_human(display_long)|uniprotkb:TUBA1B(gene name)|psi-mi:TUBA1B(display_short)|uniprotkb:Tubulin alpha-ubiquitous chain(gene name synonym)|uniprotkb:Alpha-tubulin ubiquitous(gene name synonym)|uniprotkb:Tubulin K-alpha-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479882|imex:IM-26985-331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055478.2|refseq:XP_005271411.1|refseq:XP_005271412.1|dip:DIP-29372N|ensembl:ENSG00000066135(gene)|ensembl:ENST00000372396(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016577"(histone demethylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:O75164|rcsb pdb:2GF7|rcsb pdb:2GFA|rcsb pdb:2GP3|rcsb pdb:2GP5|rcsb pdb:2OQ6|rcsb pdb:2OQ7|rcsb pdb:2OS2|rcsb pdb:2OT7|rcsb pdb:2OX0|rcsb pdb:2P5B|rcsb pdb:2PXJ|rcsb pdb:2Q8C|rcsb pdb:2Q8D|rcsb pdb:2Q8E|rcsb pdb:2QQR|rcsb pdb:2QQS|rcsb pdb:2VD7|rcsb pdb:2WWJ|rcsb pdb:2YBK|rcsb pdb:2YBP|rcsb pdb:2YBS|rcsb pdb:3NJY|rcsb pdb:3PDQ|rcsb pdb:3RVH|rcsb pdb:3U4S|rcsb pdb:4AI9|rcsb pdb:4BIS|rcsb pdb:4GD4|rcsb pdb:4URA|rcsb pdb:4V2V|rcsb pdb:4V2W|rcsb pdb:5A7N|rcsb pdb:5A7O|rcsb pdb:5A7P|rcsb pdb:5A7Q|rcsb pdb:5A7S|rcsb pdb:5A7W|rcsb pdb:5A80|rcsb pdb:5ANQ|rcsb pdb:5D6W|rcsb pdb:5D6X|rcsb pdb:5D6Y|rcsb pdb:5F2S|rcsb pdb:5F2W|rcsb pdb:5F32|rcsb pdb:5F37|rcsb pdb:5F39|rcsb pdb:5F3C|rcsb pdb:5F3E|rcsb pdb:5F3G|rcsb pdb:5F3I|rcsb pdb:5F5I|rcsb pdb:5FPV|rcsb pdb:5FWE|rcsb pdb:5FY8|rcsb pdb:5FYC|rcsb pdb:5FYH|rcsb pdb:5FYI|rcsb pdb:5LY1|rcsb pdb:5LY2|rcsb pdb:5TVR|rcsb pdb:5TVS|rcsb pdb:5VAR|rcsb pdb:5VGI|rcsb pdb:5VMP|rcsb pdb:6CG1|rcsb pdb:6CG2|rcsb pdb:6G5W|rcsb pdb:6G5X|rcsb pdb:6H4O|rcsb pdb:6H4P|rcsb pdb:6H4Q|rcsb pdb:6H4R|rcsb pdb:6H4S|rcsb pdb:6H4T|rcsb pdb:6H4U|rcsb pdb:6H4V|rcsb pdb:6H4W|rcsb pdb:6H4X|rcsb pdb:6H4Y|rcsb pdb:6H8P|rcsb pdb:6HGT|rcsb pdb:7D4A|reactome:R-HSA-3214842|reactome:R-HSA-5693565|reactome:R-HSA-9029569 refseq:NP_006073.2|ensembl:ENSG00000123416(gene)|ensembl:ENST00000336023(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-983189|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|go:"GO:0045121"(membrane raft)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68363|rcsb pdb:2E4H|rcsb pdb:5IJ0|rcsb pdb:5IJ9|rcsb pdb:5N5N|rcsb pdb:6E7B|rcsb pdb:6E7C|rcsb pdb:6I2I|go:"GO:0051301"(cell division)|rcsb pdb:6J4V|rcsb pdb:6J8O|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|rcsb pdb:6S8L|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9013407|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-2132295|reactome:R-HSA-9668328 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:P8atv/4zKIc7bVg3IZYlw5gVIHY9606 rogid:D4YpuLCXl/S+53qV7P7sF81aARY9606 rigid:mjFSsqMcLkXX1ecO3bZymOEf+cw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75164 uniprotkb:Q8TC44 intact:EBI-936709|uniprotkb:Q5VVB1|ensembl:ENSP00000361473 intact:EBI-1176274|ensembl:ENSP00000323302|uniprotkb:G3V1X0 psi-mi:kdm4a_human(display_long)|uniprotkb:KDM4A(gene name)|psi-mi:KDM4A(display_short)|uniprotkb:JMJD2(gene name synonym)|uniprotkb:KIAA0677(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2A(gene name synonym)|uniprotkb:JHDM3A(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(36) demethylase 4A"(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4A"(gene name synonym)|uniprotkb:JMJD2A(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3A(gene name synonym) psi-mi:poc1b_human(display_long)|uniprotkb:POC1B(gene name)|psi-mi:POC1B(display_short)|uniprotkb:WDR51B(gene name synonym)|uniprotkb:WD repeat-containing protein 51B(gene name synonym)|uniprotkb:Pix1(gene name synonym)|uniprotkb:Proteome of centriole protein 1B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479882|imex:IM-26985-331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055478.2|refseq:XP_005271411.1|refseq:XP_005271412.1|dip:DIP-29372N|ensembl:ENSG00000066135(gene)|ensembl:ENST00000372396(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016577"(histone demethylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:O75164|rcsb pdb:2GF7|rcsb pdb:2GFA|rcsb pdb:2GP3|rcsb pdb:2GP5|rcsb pdb:2OQ6|rcsb pdb:2OQ7|rcsb pdb:2OS2|rcsb pdb:2OT7|rcsb pdb:2OX0|rcsb pdb:2P5B|rcsb pdb:2PXJ|rcsb pdb:2Q8C|rcsb pdb:2Q8D|rcsb pdb:2Q8E|rcsb pdb:2QQR|rcsb pdb:2QQS|rcsb pdb:2VD7|rcsb pdb:2WWJ|rcsb pdb:2YBK|rcsb pdb:2YBP|rcsb pdb:2YBS|rcsb pdb:3NJY|rcsb pdb:3PDQ|rcsb pdb:3RVH|rcsb pdb:3U4S|rcsb pdb:4AI9|rcsb pdb:4BIS|rcsb pdb:4GD4|rcsb pdb:4URA|rcsb pdb:4V2V|rcsb pdb:4V2W|rcsb pdb:5A7N|rcsb pdb:5A7O|rcsb pdb:5A7P|rcsb pdb:5A7Q|rcsb pdb:5A7S|rcsb pdb:5A7W|rcsb pdb:5A80|rcsb pdb:5ANQ|rcsb pdb:5D6W|rcsb pdb:5D6X|rcsb pdb:5D6Y|rcsb pdb:5F2S|rcsb pdb:5F2W|rcsb pdb:5F32|rcsb pdb:5F37|rcsb pdb:5F39|rcsb pdb:5F3C|rcsb pdb:5F3E|rcsb pdb:5F3G|rcsb pdb:5F3I|rcsb pdb:5F5I|rcsb pdb:5FPV|rcsb pdb:5FWE|rcsb pdb:5FY8|rcsb pdb:5FYC|rcsb pdb:5FYH|rcsb pdb:5FYI|rcsb pdb:5LY1|rcsb pdb:5LY2|rcsb pdb:5TVR|rcsb pdb:5TVS|rcsb pdb:5VAR|rcsb pdb:5VGI|rcsb pdb:5VMP|rcsb pdb:6CG1|rcsb pdb:6CG2|rcsb pdb:6G5W|rcsb pdb:6G5X|rcsb pdb:6H4O|rcsb pdb:6H4P|rcsb pdb:6H4Q|rcsb pdb:6H4R|rcsb pdb:6H4S|rcsb pdb:6H4T|rcsb pdb:6H4U|rcsb pdb:6H4V|rcsb pdb:6H4W|rcsb pdb:6H4X|rcsb pdb:6H4Y|rcsb pdb:6H8P|rcsb pdb:6HGT|rcsb pdb:7D4A|reactome:R-HSA-3214842|reactome:R-HSA-5693565|reactome:R-HSA-9029569 refseq:NP_758440.1|ensembl:ENSG00000139323(gene)|ensembl:ENST00000313546(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|go:"GO:0008283"(cell population proliferation)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q8TC44|refseq:NP_001186706.1 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:P8atv/4zKIc7bVg3IZYlw5gVIHY9606 rogid:wLnp5gzUvx/+G6b2BJUDopNgpOc9606 rigid:mjFSsqMcLkXX1ecO3bZymOEf+cw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75164 uniprotkb:Q9UGL1 intact:EBI-936709|uniprotkb:Q5VVB1|ensembl:ENSP00000361473 intact:EBI-2514978|uniprotkb:Q9Y3Q5|uniprotkb:O95811|uniprotkb:Q15752|ensembl:ENSP00000356234 psi-mi:kdm4a_human(display_long)|uniprotkb:KDM4A(gene name)|psi-mi:KDM4A(display_short)|uniprotkb:JMJD2(gene name synonym)|uniprotkb:KIAA0677(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2A(gene name synonym)|uniprotkb:JHDM3A(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(36) demethylase 4A"(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4A"(gene name synonym)|uniprotkb:JMJD2A(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3A(gene name synonym) psi-mi:kdm5b_human(display_long)|uniprotkb:KDM5B(gene name)|psi-mi:KDM5B(display_short)|uniprotkb:JARID1B(gene name synonym)|uniprotkb:PLU1(gene name synonym)|uniprotkb:RBBP2H1(gene name synonym)|uniprotkb:Histone demethylase JARID1B(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1B(gene name synonym)|uniprotkb:PLU-1(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2 homolog 1(gene name synonym)|uniprotkb:Cancer/testis antigen 31(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5B"(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479882|imex:IM-26985-331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055478.2|refseq:XP_005271411.1|refseq:XP_005271412.1|dip:DIP-29372N|ensembl:ENSG00000066135(gene)|ensembl:ENST00000372396(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016577"(histone demethylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:O75164|rcsb pdb:2GF7|rcsb pdb:2GFA|rcsb pdb:2GP3|rcsb pdb:2GP5|rcsb pdb:2OQ6|rcsb pdb:2OQ7|rcsb pdb:2OS2|rcsb pdb:2OT7|rcsb pdb:2OX0|rcsb pdb:2P5B|rcsb pdb:2PXJ|rcsb pdb:2Q8C|rcsb pdb:2Q8D|rcsb pdb:2Q8E|rcsb pdb:2QQR|rcsb pdb:2QQS|rcsb pdb:2VD7|rcsb pdb:2WWJ|rcsb pdb:2YBK|rcsb pdb:2YBP|rcsb pdb:2YBS|rcsb pdb:3NJY|rcsb pdb:3PDQ|rcsb pdb:3RVH|rcsb pdb:3U4S|rcsb pdb:4AI9|rcsb pdb:4BIS|rcsb pdb:4GD4|rcsb pdb:4URA|rcsb pdb:4V2V|rcsb pdb:4V2W|rcsb pdb:5A7N|rcsb pdb:5A7O|rcsb pdb:5A7P|rcsb pdb:5A7Q|rcsb pdb:5A7S|rcsb pdb:5A7W|rcsb pdb:5A80|rcsb pdb:5ANQ|rcsb pdb:5D6W|rcsb pdb:5D6X|rcsb pdb:5D6Y|rcsb pdb:5F2S|rcsb pdb:5F2W|rcsb pdb:5F32|rcsb pdb:5F37|rcsb pdb:5F39|rcsb pdb:5F3C|rcsb pdb:5F3E|rcsb pdb:5F3G|rcsb pdb:5F3I|rcsb pdb:5F5I|rcsb pdb:5FPV|rcsb pdb:5FWE|rcsb pdb:5FY8|rcsb pdb:5FYC|rcsb pdb:5FYH|rcsb pdb:5FYI|rcsb pdb:5LY1|rcsb pdb:5LY2|rcsb pdb:5TVR|rcsb pdb:5TVS|rcsb pdb:5VAR|rcsb pdb:5VGI|rcsb pdb:5VMP|rcsb pdb:6CG1|rcsb pdb:6CG2|rcsb pdb:6G5W|rcsb pdb:6G5X|rcsb pdb:6H4O|rcsb pdb:6H4P|rcsb pdb:6H4Q|rcsb pdb:6H4R|rcsb pdb:6H4S|rcsb pdb:6H4T|rcsb pdb:6H4U|rcsb pdb:6H4V|rcsb pdb:6H4W|rcsb pdb:6H4X|rcsb pdb:6H4Y|rcsb pdb:6H8P|rcsb pdb:6HGT|rcsb pdb:7D4A|reactome:R-HSA-3214842|reactome:R-HSA-5693565|reactome:R-HSA-9029569 refseq:NP_001300971.1|refseq:NP_006609.3|dip:DIP-53652N|ensembl:ENSG00000117139(gene)|ensembl:ENST00000367265(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007338"(single fertilization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042393"(histone binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060763"(mammary duct terminal end bud growth)|go:"GO:0060992"(response to fungicide)|go:"GO:0061038"(uterus morphogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000864"(regulation of estradiol secretion)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:Q9UGL1|rcsb pdb:2MA5|rcsb pdb:2MNY|rcsb pdb:2MNZ|rcsb pdb:5A1F|rcsb pdb:5A3N|rcsb pdb:5A3P|rcsb pdb:5A3T|rcsb pdb:5A3W|rcsb pdb:5FPL|rcsb pdb:5FPU|rcsb pdb:5FUN|rcsb pdb:5FUP|rcsb pdb:5FV3|rcsb pdb:5FY4|rcsb pdb:5FY5|rcsb pdb:5FY9|rcsb pdb:5FYB|rcsb pdb:5FYS|rcsb pdb:5FYT|rcsb pdb:5FYU|rcsb pdb:5FYV|rcsb pdb:5FYY|rcsb pdb:5FYZ|rcsb pdb:5FZ0|rcsb pdb:5FZ1|rcsb pdb:5FZ3|rcsb pdb:5FZ4|rcsb pdb:5FZ6|rcsb pdb:5FZ7|rcsb pdb:5FZ8|rcsb pdb:5FZ9|rcsb pdb:5FZA|rcsb pdb:5FZB|rcsb pdb:5FZC|rcsb pdb:5FZD|rcsb pdb:5FZE|rcsb pdb:5FZF|rcsb pdb:5FZG|rcsb pdb:5FZH|rcsb pdb:5FZI|rcsb pdb:5FZK|rcsb pdb:5FZL|rcsb pdb:5FZM|go:"GO:0070306"(lens fiber cell differentiation)|rcsb pdb:5LW9|rcsb pdb:5LWB|rcsb pdb:6EIN|rcsb pdb:6EIU|rcsb pdb:6EIY|rcsb pdb:6EJ0|rcsb pdb:6EJ1|rcsb pdb:6EK6|rcsb pdb:6H4Z|rcsb pdb:6H50|rcsb pdb:6H51|rcsb pdb:6H52|rcsb pdb:6RBI|reactome:R-HSA-3214842|reactome:R-HSA-8866911 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:P8atv/4zKIc7bVg3IZYlw5gVIHY9606 rogid:HXNXUmikf5+ywMuA4UStrabarzM9606 rigid:mjFSsqMcLkXX1ecO3bZymOEf+cw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75164 uniprotkb:P30048 intact:EBI-936709|uniprotkb:Q5VVB1|ensembl:ENSP00000361473 intact:EBI-748336|intact:EBI-10975142|uniprotkb:P35690|uniprotkb:Q0D2H1|uniprotkb:Q13776|uniprotkb:Q5T5V2|uniprotkb:Q96HK4|uniprotkb:B2R7Z0|uniprotkb:D3DRC9|uniprotkb:E9PH29|ensembl:ENSP00000298510 psi-mi:kdm4a_human(display_long)|uniprotkb:KDM4A(gene name)|psi-mi:KDM4A(display_short)|uniprotkb:JMJD2(gene name synonym)|uniprotkb:KIAA0677(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2A(gene name synonym)|uniprotkb:JHDM3A(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(36) demethylase 4A"(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4A"(gene name synonym)|uniprotkb:JMJD2A(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3A(gene name synonym) psi-mi:prdx3_human(display_long)|uniprotkb:Peroxiredoxin-3(gene name synonym)|uniprotkb:Peroxiredoxin III(gene name synonym)|uniprotkb:Antioxidant protein 1(gene name synonym)|uniprotkb:Protein MER5 homolog(gene name synonym)|uniprotkb:HBC189(gene name synonym)|uniprotkb:PRDX3(gene name)|psi-mi:PRDX3(display_short)|uniprotkb:AOP1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479882|imex:IM-26985-331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055478.2|refseq:XP_005271411.1|refseq:XP_005271412.1|dip:DIP-29372N|ensembl:ENSG00000066135(gene)|ensembl:ENST00000372396(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016577"(histone demethylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:O75164|rcsb pdb:2GF7|rcsb pdb:2GFA|rcsb pdb:2GP3|rcsb pdb:2GP5|rcsb pdb:2OQ6|rcsb pdb:2OQ7|rcsb pdb:2OS2|rcsb pdb:2OT7|rcsb pdb:2OX0|rcsb pdb:2P5B|rcsb pdb:2PXJ|rcsb pdb:2Q8C|rcsb pdb:2Q8D|rcsb pdb:2Q8E|rcsb pdb:2QQR|rcsb pdb:2QQS|rcsb pdb:2VD7|rcsb pdb:2WWJ|rcsb pdb:2YBK|rcsb pdb:2YBP|rcsb pdb:2YBS|rcsb pdb:3NJY|rcsb pdb:3PDQ|rcsb pdb:3RVH|rcsb pdb:3U4S|rcsb pdb:4AI9|rcsb pdb:4BIS|rcsb pdb:4GD4|rcsb pdb:4URA|rcsb pdb:4V2V|rcsb pdb:4V2W|rcsb pdb:5A7N|rcsb pdb:5A7O|rcsb pdb:5A7P|rcsb pdb:5A7Q|rcsb pdb:5A7S|rcsb pdb:5A7W|rcsb pdb:5A80|rcsb pdb:5ANQ|rcsb pdb:5D6W|rcsb pdb:5D6X|rcsb pdb:5D6Y|rcsb pdb:5F2S|rcsb pdb:5F2W|rcsb pdb:5F32|rcsb pdb:5F37|rcsb pdb:5F39|rcsb pdb:5F3C|rcsb pdb:5F3E|rcsb pdb:5F3G|rcsb pdb:5F3I|rcsb pdb:5F5I|rcsb pdb:5FPV|rcsb pdb:5FWE|rcsb pdb:5FY8|rcsb pdb:5FYC|rcsb pdb:5FYH|rcsb pdb:5FYI|rcsb pdb:5LY1|rcsb pdb:5LY2|rcsb pdb:5TVR|rcsb pdb:5TVS|rcsb pdb:5VAR|rcsb pdb:5VGI|rcsb pdb:5VMP|rcsb pdb:6CG1|rcsb pdb:6CG2|rcsb pdb:6G5W|rcsb pdb:6G5X|rcsb pdb:6H4O|rcsb pdb:6H4P|rcsb pdb:6H4Q|rcsb pdb:6H4R|rcsb pdb:6H4S|rcsb pdb:6H4T|rcsb pdb:6H4U|rcsb pdb:6H4V|rcsb pdb:6H4W|rcsb pdb:6H4X|rcsb pdb:6H4Y|rcsb pdb:6H8P|rcsb pdb:6HGT|rcsb pdb:7D4A|reactome:R-HSA-3214842|reactome:R-HSA-5693565|reactome:R-HSA-9029569 refseq:NP_001289201.1|refseq:NP_006784.1|ensembl:ENSG00000165672(gene)|ensembl:ENST00000298510(transcript)|go:"GO:0001893"(maternal placenta development)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0008785"(alkyl hydroperoxide reductase activity)|go:"GO:0018171"(peptidyl-cysteine oxidation)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|mint:P30048|rcsb pdb:5JCG|rcsb pdb:5UCX|reactome:R-HSA-3299685|go:"GO:0005769"(early endosome)|dip:DIP-33600N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:P8atv/4zKIc7bVg3IZYlw5gVIHY9606 rogid:+J/zV8u0jGCSzTGXafxgecTv/149606 rigid:mjFSsqMcLkXX1ecO3bZymOEf+cw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75164 uniprotkb:P62995 intact:EBI-936709|uniprotkb:Q5VVB1|ensembl:ENSP00000361473 intact:EBI-725485|uniprotkb:O15449|uniprotkb:Q15815|uniprotkb:Q64283|uniprotkb:B4DVK2|uniprotkb:D3DNU3|ensembl:ENSP00000416959 psi-mi:kdm4a_human(display_long)|uniprotkb:KDM4A(gene name)|psi-mi:KDM4A(display_short)|uniprotkb:JMJD2(gene name synonym)|uniprotkb:KIAA0677(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2A(gene name synonym)|uniprotkb:JHDM3A(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(36) demethylase 4A"(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4A"(gene name synonym)|uniprotkb:JMJD2A(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3A(gene name synonym) psi-mi:tra2b_human(display_long)|uniprotkb:TRA2B(gene name)|psi-mi:TRA2B(display_short)|uniprotkb:SFRS10(gene name synonym)|uniprotkb:Transformer-2 protein homolog B(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 10(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479882|imex:IM-26985-331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055478.2|refseq:XP_005271411.1|refseq:XP_005271412.1|dip:DIP-29372N|ensembl:ENSG00000066135(gene)|ensembl:ENST00000372396(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016577"(histone demethylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:O75164|rcsb pdb:2GF7|rcsb pdb:2GFA|rcsb pdb:2GP3|rcsb pdb:2GP5|rcsb pdb:2OQ6|rcsb pdb:2OQ7|rcsb pdb:2OS2|rcsb pdb:2OT7|rcsb pdb:2OX0|rcsb pdb:2P5B|rcsb pdb:2PXJ|rcsb pdb:2Q8C|rcsb pdb:2Q8D|rcsb pdb:2Q8E|rcsb pdb:2QQR|rcsb pdb:2QQS|rcsb pdb:2VD7|rcsb pdb:2WWJ|rcsb pdb:2YBK|rcsb pdb:2YBP|rcsb pdb:2YBS|rcsb pdb:3NJY|rcsb pdb:3PDQ|rcsb pdb:3RVH|rcsb pdb:3U4S|rcsb pdb:4AI9|rcsb pdb:4BIS|rcsb pdb:4GD4|rcsb pdb:4URA|rcsb pdb:4V2V|rcsb pdb:4V2W|rcsb pdb:5A7N|rcsb pdb:5A7O|rcsb pdb:5A7P|rcsb pdb:5A7Q|rcsb pdb:5A7S|rcsb pdb:5A7W|rcsb pdb:5A80|rcsb pdb:5ANQ|rcsb pdb:5D6W|rcsb pdb:5D6X|rcsb pdb:5D6Y|rcsb pdb:5F2S|rcsb pdb:5F2W|rcsb pdb:5F32|rcsb pdb:5F37|rcsb pdb:5F39|rcsb pdb:5F3C|rcsb pdb:5F3E|rcsb pdb:5F3G|rcsb pdb:5F3I|rcsb pdb:5F5I|rcsb pdb:5FPV|rcsb pdb:5FWE|rcsb pdb:5FY8|rcsb pdb:5FYC|rcsb pdb:5FYH|rcsb pdb:5FYI|rcsb pdb:5LY1|rcsb pdb:5LY2|rcsb pdb:5TVR|rcsb pdb:5TVS|rcsb pdb:5VAR|rcsb pdb:5VGI|rcsb pdb:5VMP|rcsb pdb:6CG1|rcsb pdb:6CG2|rcsb pdb:6G5W|rcsb pdb:6G5X|rcsb pdb:6H4O|rcsb pdb:6H4P|rcsb pdb:6H4Q|rcsb pdb:6H4R|rcsb pdb:6H4S|rcsb pdb:6H4T|rcsb pdb:6H4U|rcsb pdb:6H4V|rcsb pdb:6H4W|rcsb pdb:6H4X|rcsb pdb:6H4Y|rcsb pdb:6H8P|rcsb pdb:6HGT|rcsb pdb:7D4A|reactome:R-HSA-3214842|reactome:R-HSA-5693565|reactome:R-HSA-9029569 refseq:NP_004584.1|refseq:XP_005247760.1|refseq:NP_001230808.1|refseq:XP_011511374.1|ensembl:ENSG00000136527(gene)|ensembl:ENST00000453386(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:1990403"(embryonic brain development)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P62995|rcsb pdb:2CQC|rcsb pdb:2KXN|rcsb pdb:2RRA|rcsb pdb:2RRB|reactome:R-HSA-72163|reactome:R-HSA-9013418|reactome:R-HSA-9013422|refseq:XP_016862522.1|dip:DIP-42278N - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:P8atv/4zKIc7bVg3IZYlw5gVIHY9606 rogid:6uZGeHEDlIVsb2uPeo+9NoR4tDw9606 rigid:mjFSsqMcLkXX1ecO3bZymOEf+cw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75164 uniprotkb:A2A3N6 intact:EBI-936709|uniprotkb:Q5VVB1|ensembl:ENSP00000361473 intact:EBI-11021261|uniprotkb:Q6NUK8 psi-mi:kdm4a_human(display_long)|uniprotkb:KDM4A(gene name)|psi-mi:KDM4A(display_short)|uniprotkb:JMJD2(gene name synonym)|uniprotkb:KIAA0677(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2A(gene name synonym)|uniprotkb:JHDM3A(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(36) demethylase 4A"(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4A"(gene name synonym)|uniprotkb:JMJD2A(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3A(gene name synonym) psi-mi:pipsl_human(display_long)|uniprotkb:PIPSL(gene name)|psi-mi:PIPSL(display_short)|uniprotkb:PSMD4P2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479882|imex:IM-26985-331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055478.2|refseq:XP_005271411.1|refseq:XP_005271412.1|dip:DIP-29372N|ensembl:ENSG00000066135(gene)|ensembl:ENST00000372396(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016577"(histone demethylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:O75164|rcsb pdb:2GF7|rcsb pdb:2GFA|rcsb pdb:2GP3|rcsb pdb:2GP5|rcsb pdb:2OQ6|rcsb pdb:2OQ7|rcsb pdb:2OS2|rcsb pdb:2OT7|rcsb pdb:2OX0|rcsb pdb:2P5B|rcsb pdb:2PXJ|rcsb pdb:2Q8C|rcsb pdb:2Q8D|rcsb pdb:2Q8E|rcsb pdb:2QQR|rcsb pdb:2QQS|rcsb pdb:2VD7|rcsb pdb:2WWJ|rcsb pdb:2YBK|rcsb pdb:2YBP|rcsb pdb:2YBS|rcsb pdb:3NJY|rcsb pdb:3PDQ|rcsb pdb:3RVH|rcsb pdb:3U4S|rcsb pdb:4AI9|rcsb pdb:4BIS|rcsb pdb:4GD4|rcsb pdb:4URA|rcsb pdb:4V2V|rcsb pdb:4V2W|rcsb pdb:5A7N|rcsb pdb:5A7O|rcsb pdb:5A7P|rcsb pdb:5A7Q|rcsb pdb:5A7S|rcsb pdb:5A7W|rcsb pdb:5A80|rcsb pdb:5ANQ|rcsb pdb:5D6W|rcsb pdb:5D6X|rcsb pdb:5D6Y|rcsb pdb:5F2S|rcsb pdb:5F2W|rcsb pdb:5F32|rcsb pdb:5F37|rcsb pdb:5F39|rcsb pdb:5F3C|rcsb pdb:5F3E|rcsb pdb:5F3G|rcsb pdb:5F3I|rcsb pdb:5F5I|rcsb pdb:5FPV|rcsb pdb:5FWE|rcsb pdb:5FY8|rcsb pdb:5FYC|rcsb pdb:5FYH|rcsb pdb:5FYI|rcsb pdb:5LY1|rcsb pdb:5LY2|rcsb pdb:5TVR|rcsb pdb:5TVS|rcsb pdb:5VAR|rcsb pdb:5VGI|rcsb pdb:5VMP|rcsb pdb:6CG1|rcsb pdb:6CG2|rcsb pdb:6G5W|rcsb pdb:6G5X|rcsb pdb:6H4O|rcsb pdb:6H4P|rcsb pdb:6H4Q|rcsb pdb:6H4R|rcsb pdb:6H4S|rcsb pdb:6H4T|rcsb pdb:6H4U|rcsb pdb:6H4V|rcsb pdb:6H4W|rcsb pdb:6H4X|rcsb pdb:6H4Y|rcsb pdb:6H8P|rcsb pdb:6HGT|rcsb pdb:7D4A|reactome:R-HSA-3214842|reactome:R-HSA-5693565|reactome:R-HSA-9029569 mint:A2A3N6|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR002498(Phosphatidylinositol-4-phosphate 5-kinase, core)|interpro:IPR023610|interpro:IPR027484|go:"GO:0005737"(cytoplasm)|go:"GO:0016307"(phosphatidylinositol phosphate kinase activity)|interpro:IPR036465 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:P8atv/4zKIc7bVg3IZYlw5gVIHY9606 rogid:oPDvgqGGZ5AUGip9EIapUU+5rDM9606 rigid:mjFSsqMcLkXX1ecO3bZymOEf+cw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75164 uniprotkb:Q07955 intact:EBI-936709|uniprotkb:Q5VVB1|ensembl:ENSP00000361473 intact:EBI-398920|uniprotkb:Q13809|uniprotkb:B2R6Z7|uniprotkb:D3DTZ3|ensembl:ENSP00000258962 psi-mi:kdm4a_human(display_long)|uniprotkb:KDM4A(gene name)|psi-mi:KDM4A(display_short)|uniprotkb:JMJD2(gene name synonym)|uniprotkb:KIAA0677(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2A(gene name synonym)|uniprotkb:JHDM3A(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(36) demethylase 4A"(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4A"(gene name synonym)|uniprotkb:JMJD2A(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3A(gene name synonym) psi-mi:srsf1_human(display_long)|uniprotkb:SF2(gene name synonym)|uniprotkb:SF2P33(gene name synonym)|uniprotkb:OK/SW-cl.3(orf name)|uniprotkb:SRSF1(gene name)|psi-mi:SRSF1(display_short)|uniprotkb:ASF(gene name synonym)|uniprotkb:pre-mRNA-splicing factor SF2, P33 subunit(gene name synonym)|uniprotkb:Alternative-splicing factor 1(gene name synonym)|uniprotkb:SFRS1(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479882|imex:IM-26985-331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055478.2|refseq:XP_005271411.1|refseq:XP_005271412.1|dip:DIP-29372N|ensembl:ENSG00000066135(gene)|ensembl:ENST00000372396(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016577"(histone demethylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:O75164|rcsb pdb:2GF7|rcsb pdb:2GFA|rcsb pdb:2GP3|rcsb pdb:2GP5|rcsb pdb:2OQ6|rcsb pdb:2OQ7|rcsb pdb:2OS2|rcsb pdb:2OT7|rcsb pdb:2OX0|rcsb pdb:2P5B|rcsb pdb:2PXJ|rcsb pdb:2Q8C|rcsb pdb:2Q8D|rcsb pdb:2Q8E|rcsb pdb:2QQR|rcsb pdb:2QQS|rcsb pdb:2VD7|rcsb pdb:2WWJ|rcsb pdb:2YBK|rcsb pdb:2YBP|rcsb pdb:2YBS|rcsb pdb:3NJY|rcsb pdb:3PDQ|rcsb pdb:3RVH|rcsb pdb:3U4S|rcsb pdb:4AI9|rcsb pdb:4BIS|rcsb pdb:4GD4|rcsb pdb:4URA|rcsb pdb:4V2V|rcsb pdb:4V2W|rcsb pdb:5A7N|rcsb pdb:5A7O|rcsb pdb:5A7P|rcsb pdb:5A7Q|rcsb pdb:5A7S|rcsb pdb:5A7W|rcsb pdb:5A80|rcsb pdb:5ANQ|rcsb pdb:5D6W|rcsb pdb:5D6X|rcsb pdb:5D6Y|rcsb pdb:5F2S|rcsb pdb:5F2W|rcsb pdb:5F32|rcsb pdb:5F37|rcsb pdb:5F39|rcsb pdb:5F3C|rcsb pdb:5F3E|rcsb pdb:5F3G|rcsb pdb:5F3I|rcsb pdb:5F5I|rcsb pdb:5FPV|rcsb pdb:5FWE|rcsb pdb:5FY8|rcsb pdb:5FYC|rcsb pdb:5FYH|rcsb pdb:5FYI|rcsb pdb:5LY1|rcsb pdb:5LY2|rcsb pdb:5TVR|rcsb pdb:5TVS|rcsb pdb:5VAR|rcsb pdb:5VGI|rcsb pdb:5VMP|rcsb pdb:6CG1|rcsb pdb:6CG2|rcsb pdb:6G5W|rcsb pdb:6G5X|rcsb pdb:6H4O|rcsb pdb:6H4P|rcsb pdb:6H4Q|rcsb pdb:6H4R|rcsb pdb:6H4S|rcsb pdb:6H4T|rcsb pdb:6H4U|rcsb pdb:6H4V|rcsb pdb:6H4W|rcsb pdb:6H4X|rcsb pdb:6H4Y|rcsb pdb:6H8P|rcsb pdb:6HGT|rcsb pdb:7D4A|reactome:R-HSA-3214842|reactome:R-HSA-5693565|reactome:R-HSA-9029569 refseq:NP_001071634.1|refseq:NP_008855.1|dip:DIP-2155N|ensembl:ENSG00000136450(gene)|ensembl:ENST00000258962(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0051028"(mRNA transport)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097421"(liver regeneration)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034520|interpro:IPR035979|mint:Q07955|rcsb pdb:2M7S|rcsb pdb:2M8D|rcsb pdb:2O3D|rcsb pdb:3BEG|rcsb pdb:4C0O|rcsb pdb:6HPJ|rcsb pdb:7ABG|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:1X4A - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:P8atv/4zKIc7bVg3IZYlw5gVIHY9606 rogid:6/IA4a3btkfSBtMH32iCe+rqZ8Y9606 rigid:mjFSsqMcLkXX1ecO3bZymOEf+cw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75164 uniprotkb:Q9Y3Y2 intact:EBI-936709|uniprotkb:Q5VVB1|ensembl:ENSP00000361473 intact:EBI-347794|uniprotkb:Q2VPI9|uniprotkb:Q5T7Y8|uniprotkb:Q5T7Z0|uniprotkb:Q6NSM4|uniprotkb:Q6PB28|uniprotkb:Q8WYT9|uniprotkb:Q9BUC5|uniprotkb:Q9H034|uniprotkb:Q9H2L0|uniprotkb:Q0VAQ8|uniprotkb:D3DV55|uniprotkb:Q5T7Y9|ensembl:ENSP00000357683 psi-mi:kdm4a_human(display_long)|uniprotkb:KDM4A(gene name)|psi-mi:KDM4A(display_short)|uniprotkb:JMJD2(gene name synonym)|uniprotkb:KIAA0677(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2A(gene name synonym)|uniprotkb:JHDM3A(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(36) demethylase 4A"(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4A"(gene name synonym)|uniprotkb:JMJD2A(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3A(gene name synonym) psi-mi:chtop_human(display_long)|uniprotkb:HT031(orf name)|uniprotkb:PP7704(orf name)|uniprotkb:FOP(gene name synonym)|uniprotkb:CHTOP(gene name)|psi-mi:CHTOP(display_short)|uniprotkb:C1orf77(gene name synonym)|uniprotkb:Friend of PRMT1 protein(gene name synonym)|uniprotkb:Small arginine- and glycine-rich protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479882|imex:IM-26985-331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055478.2|refseq:XP_005271411.1|refseq:XP_005271412.1|dip:DIP-29372N|ensembl:ENSG00000066135(gene)|ensembl:ENST00000372396(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016577"(histone demethylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:O75164|rcsb pdb:2GF7|rcsb pdb:2GFA|rcsb pdb:2GP3|rcsb pdb:2GP5|rcsb pdb:2OQ6|rcsb pdb:2OQ7|rcsb pdb:2OS2|rcsb pdb:2OT7|rcsb pdb:2OX0|rcsb pdb:2P5B|rcsb pdb:2PXJ|rcsb pdb:2Q8C|rcsb pdb:2Q8D|rcsb pdb:2Q8E|rcsb pdb:2QQR|rcsb pdb:2QQS|rcsb pdb:2VD7|rcsb pdb:2WWJ|rcsb pdb:2YBK|rcsb pdb:2YBP|rcsb pdb:2YBS|rcsb pdb:3NJY|rcsb pdb:3PDQ|rcsb pdb:3RVH|rcsb pdb:3U4S|rcsb pdb:4AI9|rcsb pdb:4BIS|rcsb pdb:4GD4|rcsb pdb:4URA|rcsb pdb:4V2V|rcsb pdb:4V2W|rcsb pdb:5A7N|rcsb pdb:5A7O|rcsb pdb:5A7P|rcsb pdb:5A7Q|rcsb pdb:5A7S|rcsb pdb:5A7W|rcsb pdb:5A80|rcsb pdb:5ANQ|rcsb pdb:5D6W|rcsb pdb:5D6X|rcsb pdb:5D6Y|rcsb pdb:5F2S|rcsb pdb:5F2W|rcsb pdb:5F32|rcsb pdb:5F37|rcsb pdb:5F39|rcsb pdb:5F3C|rcsb pdb:5F3E|rcsb pdb:5F3G|rcsb pdb:5F3I|rcsb pdb:5F5I|rcsb pdb:5FPV|rcsb pdb:5FWE|rcsb pdb:5FY8|rcsb pdb:5FYC|rcsb pdb:5FYH|rcsb pdb:5FYI|rcsb pdb:5LY1|rcsb pdb:5LY2|rcsb pdb:5TVR|rcsb pdb:5TVS|rcsb pdb:5VAR|rcsb pdb:5VGI|rcsb pdb:5VMP|rcsb pdb:6CG1|rcsb pdb:6CG2|rcsb pdb:6G5W|rcsb pdb:6G5X|rcsb pdb:6H4O|rcsb pdb:6H4P|rcsb pdb:6H4Q|rcsb pdb:6H4R|rcsb pdb:6H4S|rcsb pdb:6H4T|rcsb pdb:6H4U|rcsb pdb:6H4V|rcsb pdb:6H4W|rcsb pdb:6H4X|rcsb pdb:6H4Y|rcsb pdb:6H8P|rcsb pdb:6HGT|rcsb pdb:7D4A|reactome:R-HSA-3214842|reactome:R-HSA-5693565|reactome:R-HSA-9029569 refseq:NP_001304006.1|refseq:NP_001193541.1|refseq:NP_056422.2|refseq:NP_001231593.1|ensembl:ENSG00000160679(gene)|ensembl:ENST00000368694(transcript)|go:"GO:0000346"(transcription export complex)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0051096"(positive regulation of helicase activity)|interpro:IPR025715|mint:Q9Y3Y2|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:P8atv/4zKIc7bVg3IZYlw5gVIHY9606 rogid:mNq0QTGQnGABQwIL2S90Hbp3Nm89606 rigid:mjFSsqMcLkXX1ecO3bZymOEf+cw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75164 uniprotkb:P62316 intact:EBI-936709|uniprotkb:Q5VVB1|ensembl:ENSP00000361473 intact:EBI-297993|uniprotkb:P43330|ensembl:ENSP00000342374|ensembl:ENSP00000465216|uniprotkb:A8K797|uniprotkb:J3KPM5 psi-mi:kdm4a_human(display_long)|uniprotkb:KDM4A(gene name)|psi-mi:KDM4A(display_short)|uniprotkb:JMJD2(gene name synonym)|uniprotkb:KIAA0677(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2A(gene name synonym)|uniprotkb:JHDM3A(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(36) demethylase 4A"(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4A"(gene name synonym)|uniprotkb:JMJD2A(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3A(gene name synonym) psi-mi:smd2_human(display_long)|uniprotkb:SNRPD2(gene name)|psi-mi:SNRPD2(display_short)|uniprotkb:snRNP core protein D2(gene name synonym)|uniprotkb:SNRPD1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479882|imex:IM-26985-331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055478.2|refseq:XP_005271411.1|refseq:XP_005271412.1|dip:DIP-29372N|ensembl:ENSG00000066135(gene)|ensembl:ENST00000372396(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016577"(histone demethylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:O75164|rcsb pdb:2GF7|rcsb pdb:2GFA|rcsb pdb:2GP3|rcsb pdb:2GP5|rcsb pdb:2OQ6|rcsb pdb:2OQ7|rcsb pdb:2OS2|rcsb pdb:2OT7|rcsb pdb:2OX0|rcsb pdb:2P5B|rcsb pdb:2PXJ|rcsb pdb:2Q8C|rcsb pdb:2Q8D|rcsb pdb:2Q8E|rcsb pdb:2QQR|rcsb pdb:2QQS|rcsb pdb:2VD7|rcsb pdb:2WWJ|rcsb pdb:2YBK|rcsb pdb:2YBP|rcsb pdb:2YBS|rcsb pdb:3NJY|rcsb pdb:3PDQ|rcsb pdb:3RVH|rcsb pdb:3U4S|rcsb pdb:4AI9|rcsb pdb:4BIS|rcsb pdb:4GD4|rcsb pdb:4URA|rcsb pdb:4V2V|rcsb pdb:4V2W|rcsb pdb:5A7N|rcsb pdb:5A7O|rcsb pdb:5A7P|rcsb pdb:5A7Q|rcsb pdb:5A7S|rcsb pdb:5A7W|rcsb pdb:5A80|rcsb pdb:5ANQ|rcsb pdb:5D6W|rcsb pdb:5D6X|rcsb pdb:5D6Y|rcsb pdb:5F2S|rcsb pdb:5F2W|rcsb pdb:5F32|rcsb pdb:5F37|rcsb pdb:5F39|rcsb pdb:5F3C|rcsb pdb:5F3E|rcsb pdb:5F3G|rcsb pdb:5F3I|rcsb pdb:5F5I|rcsb pdb:5FPV|rcsb pdb:5FWE|rcsb pdb:5FY8|rcsb pdb:5FYC|rcsb pdb:5FYH|rcsb pdb:5FYI|rcsb pdb:5LY1|rcsb pdb:5LY2|rcsb pdb:5TVR|rcsb pdb:5TVS|rcsb pdb:5VAR|rcsb pdb:5VGI|rcsb pdb:5VMP|rcsb pdb:6CG1|rcsb pdb:6CG2|rcsb pdb:6G5W|rcsb pdb:6G5X|rcsb pdb:6H4O|rcsb pdb:6H4P|rcsb pdb:6H4Q|rcsb pdb:6H4R|rcsb pdb:6H4S|rcsb pdb:6H4T|rcsb pdb:6H4U|rcsb pdb:6H4V|rcsb pdb:6H4W|rcsb pdb:6H4X|rcsb pdb:6H4Y|rcsb pdb:6H8P|rcsb pdb:6HGT|rcsb pdb:7D4A|reactome:R-HSA-3214842|reactome:R-HSA-5693565|reactome:R-HSA-9029569 ensembl:ENSG00000125743(gene)|ensembl:ENST00000342669(transcript)|ensembl:ENST00000588301(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990446"(U1 snRNP binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027248|mint:P62316|rcsb pdb:1B34|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:NP_004588.1|refseq:NP_808210.2|dip:DIP-31219N - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:P8atv/4zKIc7bVg3IZYlw5gVIHY9606 rogid:4OshNPT6N4dOcWMVXrF5Fm8dcnI9606 rigid:mjFSsqMcLkXX1ecO3bZymOEf+cw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75164 uniprotkb:O94903 intact:EBI-936709|uniprotkb:Q5VVB1|ensembl:ENSP00000361473 intact:EBI-2860631|uniprotkb:Q6FI94|ensembl:ENSP00000333551 psi-mi:kdm4a_human(display_long)|uniprotkb:KDM4A(gene name)|psi-mi:KDM4A(display_short)|uniprotkb:JMJD2(gene name synonym)|uniprotkb:KIAA0677(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2A(gene name synonym)|uniprotkb:JHDM3A(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(36) demethylase 4A"(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4A"(gene name synonym)|uniprotkb:JMJD2A(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3A(gene name synonym) psi-mi:plphp_human(display_long)|uniprotkb:PLPBP(gene name)|psi-mi:PLPBP(display_short)|uniprotkb:PROSC(gene name synonym)|uniprotkb:Proline synthase co-transcribed bacterial homolog protein(gene name synonym)|uniprotkb:Pyridoxal phosphate-binding protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479882|imex:IM-26985-331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055478.2|refseq:XP_005271411.1|refseq:XP_005271412.1|dip:DIP-29372N|ensembl:ENSG00000066135(gene)|ensembl:ENST00000372396(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016577"(histone demethylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:O75164|rcsb pdb:2GF7|rcsb pdb:2GFA|rcsb pdb:2GP3|rcsb pdb:2GP5|rcsb pdb:2OQ6|rcsb pdb:2OQ7|rcsb pdb:2OS2|rcsb pdb:2OT7|rcsb pdb:2OX0|rcsb pdb:2P5B|rcsb pdb:2PXJ|rcsb pdb:2Q8C|rcsb pdb:2Q8D|rcsb pdb:2Q8E|rcsb pdb:2QQR|rcsb pdb:2QQS|rcsb pdb:2VD7|rcsb pdb:2WWJ|rcsb pdb:2YBK|rcsb pdb:2YBP|rcsb pdb:2YBS|rcsb pdb:3NJY|rcsb pdb:3PDQ|rcsb pdb:3RVH|rcsb pdb:3U4S|rcsb pdb:4AI9|rcsb pdb:4BIS|rcsb pdb:4GD4|rcsb pdb:4URA|rcsb pdb:4V2V|rcsb pdb:4V2W|rcsb pdb:5A7N|rcsb pdb:5A7O|rcsb pdb:5A7P|rcsb pdb:5A7Q|rcsb pdb:5A7S|rcsb pdb:5A7W|rcsb pdb:5A80|rcsb pdb:5ANQ|rcsb pdb:5D6W|rcsb pdb:5D6X|rcsb pdb:5D6Y|rcsb pdb:5F2S|rcsb pdb:5F2W|rcsb pdb:5F32|rcsb pdb:5F37|rcsb pdb:5F39|rcsb pdb:5F3C|rcsb pdb:5F3E|rcsb pdb:5F3G|rcsb pdb:5F3I|rcsb pdb:5F5I|rcsb pdb:5FPV|rcsb pdb:5FWE|rcsb pdb:5FY8|rcsb pdb:5FYC|rcsb pdb:5FYH|rcsb pdb:5FYI|rcsb pdb:5LY1|rcsb pdb:5LY2|rcsb pdb:5TVR|rcsb pdb:5TVS|rcsb pdb:5VAR|rcsb pdb:5VGI|rcsb pdb:5VMP|rcsb pdb:6CG1|rcsb pdb:6CG2|rcsb pdb:6G5W|rcsb pdb:6G5X|rcsb pdb:6H4O|rcsb pdb:6H4P|rcsb pdb:6H4Q|rcsb pdb:6H4R|rcsb pdb:6H4S|rcsb pdb:6H4T|rcsb pdb:6H4U|rcsb pdb:6H4V|rcsb pdb:6H4W|rcsb pdb:6H4X|rcsb pdb:6H4Y|rcsb pdb:6H8P|rcsb pdb:6HGT|rcsb pdb:7D4A|reactome:R-HSA-3214842|reactome:R-HSA-5693565|reactome:R-HSA-9029569 refseq:NP_009129.1|ensembl:ENSG00000147471(gene)|ensembl:ENST00000328195(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030170"(pyridoxal phosphate binding)|interpro:IPR001608(Alanine racemase, N-terminal)|interpro:IPR011078(Predicted pyridoxal phosphate-dependent enzyme, YBL036C type)|interpro:IPR029066|mint:O94903 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:P8atv/4zKIc7bVg3IZYlw5gVIHY9606 rogid:xrOEPMjG0y+otG21Al6Q0UuQcEY9606 rigid:mjFSsqMcLkXX1ecO3bZymOEf+cw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75164 uniprotkb:Q13043 intact:EBI-936709|uniprotkb:Q5VVB1|ensembl:ENSP00000361473 intact:EBI-367376|uniprotkb:Q15802|uniprotkb:Q4G156|ensembl:ENSP00000361892|uniprotkb:Q5H982|uniprotkb:Q6PD60|uniprotkb:Q9BR32|uniprotkb:Q9NTZ4|uniprotkb:B2RCR8 psi-mi:kdm4a_human(display_long)|uniprotkb:KDM4A(gene name)|psi-mi:KDM4A(display_short)|uniprotkb:JMJD2(gene name synonym)|uniprotkb:KIAA0677(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2A(gene name synonym)|uniprotkb:JHDM3A(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(36) demethylase 4A"(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4A"(gene name synonym)|uniprotkb:JMJD2A(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3A(gene name synonym) psi-mi:stk4_human(display_long)|uniprotkb:STK4(gene name)|psi-mi:STK4(display_short)|uniprotkb:MST1(gene name synonym)|uniprotkb:STE20-like kinase MST1(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Krs-2(gene name synonym)|uniprotkb:KRS2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479882|imex:IM-26985-331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055478.2|refseq:XP_005271411.1|refseq:XP_005271412.1|dip:DIP-29372N|ensembl:ENSG00000066135(gene)|ensembl:ENST00000372396(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016577"(histone demethylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:O75164|rcsb pdb:2GF7|rcsb pdb:2GFA|rcsb pdb:2GP3|rcsb pdb:2GP5|rcsb pdb:2OQ6|rcsb pdb:2OQ7|rcsb pdb:2OS2|rcsb pdb:2OT7|rcsb pdb:2OX0|rcsb pdb:2P5B|rcsb pdb:2PXJ|rcsb pdb:2Q8C|rcsb pdb:2Q8D|rcsb pdb:2Q8E|rcsb pdb:2QQR|rcsb pdb:2QQS|rcsb pdb:2VD7|rcsb pdb:2WWJ|rcsb pdb:2YBK|rcsb pdb:2YBP|rcsb pdb:2YBS|rcsb pdb:3NJY|rcsb pdb:3PDQ|rcsb pdb:3RVH|rcsb pdb:3U4S|rcsb pdb:4AI9|rcsb pdb:4BIS|rcsb pdb:4GD4|rcsb pdb:4URA|rcsb pdb:4V2V|rcsb pdb:4V2W|rcsb pdb:5A7N|rcsb pdb:5A7O|rcsb pdb:5A7P|rcsb pdb:5A7Q|rcsb pdb:5A7S|rcsb pdb:5A7W|rcsb pdb:5A80|rcsb pdb:5ANQ|rcsb pdb:5D6W|rcsb pdb:5D6X|rcsb pdb:5D6Y|rcsb pdb:5F2S|rcsb pdb:5F2W|rcsb pdb:5F32|rcsb pdb:5F37|rcsb pdb:5F39|rcsb pdb:5F3C|rcsb pdb:5F3E|rcsb pdb:5F3G|rcsb pdb:5F3I|rcsb pdb:5F5I|rcsb pdb:5FPV|rcsb pdb:5FWE|rcsb pdb:5FY8|rcsb pdb:5FYC|rcsb pdb:5FYH|rcsb pdb:5FYI|rcsb pdb:5LY1|rcsb pdb:5LY2|rcsb pdb:5TVR|rcsb pdb:5TVS|rcsb pdb:5VAR|rcsb pdb:5VGI|rcsb pdb:5VMP|rcsb pdb:6CG1|rcsb pdb:6CG2|rcsb pdb:6G5W|rcsb pdb:6G5X|rcsb pdb:6H4O|rcsb pdb:6H4P|rcsb pdb:6H4Q|rcsb pdb:6H4R|rcsb pdb:6H4S|rcsb pdb:6H4T|rcsb pdb:6H4U|rcsb pdb:6H4V|rcsb pdb:6H4W|rcsb pdb:6H4X|rcsb pdb:6H4Y|rcsb pdb:6H8P|rcsb pdb:6HGT|rcsb pdb:7D4A|reactome:R-HSA-3214842|reactome:R-HSA-5693565|reactome:R-HSA-9029569 ensembl:ENSG00000101109(gene)|ensembl:ENST00000372806(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001841"(neural tube formation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003157"(endocardium development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|refseq:NP_006273.1|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016604"(nuclear body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|refseq:XP_005260590.1|go:"GO:0060800"(regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024205|interpro:IPR036674|mint:Q13043|rcsb pdb:2JO8|rcsb pdb:3COM|rcsb pdb:4NR2|rcsb pdb:4OH8|rcsb pdb:5TWG|rcsb pdb:5TWH|rcsb pdb:6YAT|reactome:R-HSA-2028269|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051262"(protein tetramerization)|go:"GO:0060215"(primitive hemopoiesis)|dip:DIP-32491N - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:P8atv/4zKIc7bVg3IZYlw5gVIHY9606 rogid:Z/Uf9T1T/jGvNFWfAkpSf5cQSWY9606 rigid:mjFSsqMcLkXX1ecO3bZymOEf+cw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75164 uniprotkb:Q9BY77 intact:EBI-936709|uniprotkb:Q5VVB1|ensembl:ENSP00000361473 intact:EBI-1776152|uniprotkb:Q5H972|uniprotkb:Q6PGN6|uniprotkb:Q7Z6Z0|uniprotkb:Q9NSP5|uniprotkb:Q9NSP6|uniprotkb:A8K6F8|uniprotkb:A8K6V9|uniprotkb:Q009A7|ensembl:ENSP00000252115 psi-mi:kdm4a_human(display_long)|uniprotkb:KDM4A(gene name)|psi-mi:KDM4A(display_short)|uniprotkb:JMJD2(gene name synonym)|uniprotkb:KIAA0677(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2A(gene name synonym)|uniprotkb:JHDM3A(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(36) demethylase 4A"(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4A"(gene name synonym)|uniprotkb:JMJD2A(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3A(gene name synonym) psi-mi:pdip3_human(display_long)|uniprotkb:POLDIP3(gene name)|psi-mi:POLDIP3(display_short)|uniprotkb:KIAA1649(gene name synonym)|uniprotkb:PDIP46(gene name synonym)|uniprotkb:46 kDa DNA polymerase delta interaction protein(gene name synonym)|uniprotkb:S6K1 Aly/REF-like target(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479882|imex:IM-26985-331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055478.2|refseq:XP_005271411.1|refseq:XP_005271412.1|dip:DIP-29372N|ensembl:ENSG00000066135(gene)|ensembl:ENST00000372396(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016577"(histone demethylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:O75164|rcsb pdb:2GF7|rcsb pdb:2GFA|rcsb pdb:2GP3|rcsb pdb:2GP5|rcsb pdb:2OQ6|rcsb pdb:2OQ7|rcsb pdb:2OS2|rcsb pdb:2OT7|rcsb pdb:2OX0|rcsb pdb:2P5B|rcsb pdb:2PXJ|rcsb pdb:2Q8C|rcsb pdb:2Q8D|rcsb pdb:2Q8E|rcsb pdb:2QQR|rcsb pdb:2QQS|rcsb pdb:2VD7|rcsb pdb:2WWJ|rcsb pdb:2YBK|rcsb pdb:2YBP|rcsb pdb:2YBS|rcsb pdb:3NJY|rcsb pdb:3PDQ|rcsb pdb:3RVH|rcsb pdb:3U4S|rcsb pdb:4AI9|rcsb pdb:4BIS|rcsb pdb:4GD4|rcsb pdb:4URA|rcsb pdb:4V2V|rcsb pdb:4V2W|rcsb pdb:5A7N|rcsb pdb:5A7O|rcsb pdb:5A7P|rcsb pdb:5A7Q|rcsb pdb:5A7S|rcsb pdb:5A7W|rcsb pdb:5A80|rcsb pdb:5ANQ|rcsb pdb:5D6W|rcsb pdb:5D6X|rcsb pdb:5D6Y|rcsb pdb:5F2S|rcsb pdb:5F2W|rcsb pdb:5F32|rcsb pdb:5F37|rcsb pdb:5F39|rcsb pdb:5F3C|rcsb pdb:5F3E|rcsb pdb:5F3G|rcsb pdb:5F3I|rcsb pdb:5F5I|rcsb pdb:5FPV|rcsb pdb:5FWE|rcsb pdb:5FY8|rcsb pdb:5FYC|rcsb pdb:5FYH|rcsb pdb:5FYI|rcsb pdb:5LY1|rcsb pdb:5LY2|rcsb pdb:5TVR|rcsb pdb:5TVS|rcsb pdb:5VAR|rcsb pdb:5VGI|rcsb pdb:5VMP|rcsb pdb:6CG1|rcsb pdb:6CG2|rcsb pdb:6G5W|rcsb pdb:6G5X|rcsb pdb:6H4O|rcsb pdb:6H4P|rcsb pdb:6H4Q|rcsb pdb:6H4R|rcsb pdb:6H4S|rcsb pdb:6H4T|rcsb pdb:6H4U|rcsb pdb:6H4V|rcsb pdb:6H4W|rcsb pdb:6H4X|rcsb pdb:6H4Y|rcsb pdb:6H8P|rcsb pdb:6HGT|rcsb pdb:7D4A|reactome:R-HSA-3214842|reactome:R-HSA-5693565|reactome:R-HSA-9029569 refseq:NP_115687.2|refseq:NP_835237.1|ensembl:ENSG00000100227(gene)|ensembl:ENST00000252115(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034784|interpro:IPR035979|mint:Q9BY77|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856 - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:P8atv/4zKIc7bVg3IZYlw5gVIHY9606 rogid:64+Bf4QpCDdKkZMMH/7afOnOKH09606 rigid:mjFSsqMcLkXX1ecO3bZymOEf+cw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75164 uniprotkb:O14950 intact:EBI-936709|uniprotkb:Q5VVB1|ensembl:ENSP00000361473 intact:EBI-1642165|uniprotkb:D3DUH6|intact:EBI-2826593|uniprotkb:Q7Z5Z4|uniprotkb:Q13182|ensembl:ENSP00000237500|ensembl:ENSP00000383037|ensembl:ENSP00000463559|ensembl:ENSP00000464464|ensembl:ENSP00000496809 psi-mi:kdm4a_human(display_long)|uniprotkb:KDM4A(gene name)|psi-mi:KDM4A(display_short)|uniprotkb:JMJD2(gene name synonym)|uniprotkb:KIAA0677(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2A(gene name synonym)|uniprotkb:JHDM3A(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(36) demethylase 4A"(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4A"(gene name synonym)|uniprotkb:JMJD2A(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3A(gene name synonym) psi-mi:ml12b_human(display_long)|uniprotkb:MYL12B(gene name)|psi-mi:MYL12B(display_short)|uniprotkb:MRLC2(gene name synonym)|uniprotkb:Myosin regulatory light chain 2-B, smooth muscle isoform(gene name synonym)|uniprotkb:MLC-2A(gene name synonym)|uniprotkb:SHUJUN-1(gene name synonym)|uniprotkb:MYLC2B(gene name synonym)|uniprotkb:Myosin regulatory light chain MRLC2(gene name synonym)|uniprotkb:Myosin regulatory light chain 20 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479882|imex:IM-26985-331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055478.2|refseq:XP_005271411.1|refseq:XP_005271412.1|dip:DIP-29372N|ensembl:ENSG00000066135(gene)|ensembl:ENST00000372396(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016577"(histone demethylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:O75164|rcsb pdb:2GF7|rcsb pdb:2GFA|rcsb pdb:2GP3|rcsb pdb:2GP5|rcsb pdb:2OQ6|rcsb pdb:2OQ7|rcsb pdb:2OS2|rcsb pdb:2OT7|rcsb pdb:2OX0|rcsb pdb:2P5B|rcsb pdb:2PXJ|rcsb pdb:2Q8C|rcsb pdb:2Q8D|rcsb pdb:2Q8E|rcsb pdb:2QQR|rcsb pdb:2QQS|rcsb pdb:2VD7|rcsb pdb:2WWJ|rcsb pdb:2YBK|rcsb pdb:2YBP|rcsb pdb:2YBS|rcsb pdb:3NJY|rcsb pdb:3PDQ|rcsb pdb:3RVH|rcsb pdb:3U4S|rcsb pdb:4AI9|rcsb pdb:4BIS|rcsb pdb:4GD4|rcsb pdb:4URA|rcsb pdb:4V2V|rcsb pdb:4V2W|rcsb pdb:5A7N|rcsb pdb:5A7O|rcsb pdb:5A7P|rcsb pdb:5A7Q|rcsb pdb:5A7S|rcsb pdb:5A7W|rcsb pdb:5A80|rcsb pdb:5ANQ|rcsb pdb:5D6W|rcsb pdb:5D6X|rcsb pdb:5D6Y|rcsb pdb:5F2S|rcsb pdb:5F2W|rcsb pdb:5F32|rcsb pdb:5F37|rcsb pdb:5F39|rcsb pdb:5F3C|rcsb pdb:5F3E|rcsb pdb:5F3G|rcsb pdb:5F3I|rcsb pdb:5F5I|rcsb pdb:5FPV|rcsb pdb:5FWE|rcsb pdb:5FY8|rcsb pdb:5FYC|rcsb pdb:5FYH|rcsb pdb:5FYI|rcsb pdb:5LY1|rcsb pdb:5LY2|rcsb pdb:5TVR|rcsb pdb:5TVS|rcsb pdb:5VAR|rcsb pdb:5VGI|rcsb pdb:5VMP|rcsb pdb:6CG1|rcsb pdb:6CG2|rcsb pdb:6G5W|rcsb pdb:6G5X|rcsb pdb:6H4O|rcsb pdb:6H4P|rcsb pdb:6H4Q|rcsb pdb:6H4R|rcsb pdb:6H4S|rcsb pdb:6H4T|rcsb pdb:6H4U|rcsb pdb:6H4V|rcsb pdb:6H4W|rcsb pdb:6H4X|rcsb pdb:6H4Y|rcsb pdb:6H8P|rcsb pdb:6HGT|rcsb pdb:7D4A|reactome:R-HSA-3214842|reactome:R-HSA-5693565|reactome:R-HSA-9029569 refseq:NP_001138416.1|refseq:NP_001138417.1|refseq:NP_291024.1|refseq:NP_001289978.1|ensembl:ENSG00000118680(gene)|ensembl:ENST00000237500(transcript)|ensembl:ENST00000400175(transcript)|ensembl:ENST00000581193(transcript)|ensembl:ENST00000584539(transcript)|ensembl:ENST00000648965(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016460"(myosin II complex)|go:"GO:0030018"(Z disc)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR015070(Region of unknown function DUF1880)|interpro:IPR018247|mint:O14950|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-445355|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123 - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:P8atv/4zKIc7bVg3IZYlw5gVIHY9606 rogid:5jOP3J5TW0eU9zwalQ2S4Oist4k9606 rigid:mjFSsqMcLkXX1ecO3bZymOEf+cw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75164 uniprotkb:P05089 intact:EBI-936709|uniprotkb:Q5VVB1|ensembl:ENSP00000361473 intact:EBI-2513844|uniprotkb:Q5JWT6|uniprotkb:Q5JWT5|uniprotkb:Q9BS50|uniprotkb:Q8TE72|uniprotkb:A6NEA0|ensembl:ENSP00000357066 psi-mi:kdm4a_human(display_long)|uniprotkb:KDM4A(gene name)|psi-mi:KDM4A(display_short)|uniprotkb:JMJD2(gene name synonym)|uniprotkb:KIAA0677(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2A(gene name synonym)|uniprotkb:JHDM3A(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(36) demethylase 4A"(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4A"(gene name synonym)|uniprotkb:JMJD2A(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3A(gene name synonym) psi-mi:argi1_human(display_long)|uniprotkb:ARG1(gene name)|psi-mi:ARG1(display_short)|uniprotkb:Type I arginase(gene name synonym)|uniprotkb:Liver-type arginase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479882|imex:IM-26985-331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055478.2|refseq:XP_005271411.1|refseq:XP_005271412.1|dip:DIP-29372N|ensembl:ENSG00000066135(gene)|ensembl:ENST00000372396(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016577"(histone demethylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:O75164|rcsb pdb:2GF7|rcsb pdb:2GFA|rcsb pdb:2GP3|rcsb pdb:2GP5|rcsb pdb:2OQ6|rcsb pdb:2OQ7|rcsb pdb:2OS2|rcsb pdb:2OT7|rcsb pdb:2OX0|rcsb pdb:2P5B|rcsb pdb:2PXJ|rcsb pdb:2Q8C|rcsb pdb:2Q8D|rcsb pdb:2Q8E|rcsb pdb:2QQR|rcsb pdb:2QQS|rcsb pdb:2VD7|rcsb pdb:2WWJ|rcsb pdb:2YBK|rcsb pdb:2YBP|rcsb pdb:2YBS|rcsb pdb:3NJY|rcsb pdb:3PDQ|rcsb pdb:3RVH|rcsb pdb:3U4S|rcsb pdb:4AI9|rcsb pdb:4BIS|rcsb pdb:4GD4|rcsb pdb:4URA|rcsb pdb:4V2V|rcsb pdb:4V2W|rcsb pdb:5A7N|rcsb pdb:5A7O|rcsb pdb:5A7P|rcsb pdb:5A7Q|rcsb pdb:5A7S|rcsb pdb:5A7W|rcsb pdb:5A80|rcsb pdb:5ANQ|rcsb pdb:5D6W|rcsb pdb:5D6X|rcsb pdb:5D6Y|rcsb pdb:5F2S|rcsb pdb:5F2W|rcsb pdb:5F32|rcsb pdb:5F37|rcsb pdb:5F39|rcsb pdb:5F3C|rcsb pdb:5F3E|rcsb pdb:5F3G|rcsb pdb:5F3I|rcsb pdb:5F5I|rcsb pdb:5FPV|rcsb pdb:5FWE|rcsb pdb:5FY8|rcsb pdb:5FYC|rcsb pdb:5FYH|rcsb pdb:5FYI|rcsb pdb:5LY1|rcsb pdb:5LY2|rcsb pdb:5TVR|rcsb pdb:5TVS|rcsb pdb:5VAR|rcsb pdb:5VGI|rcsb pdb:5VMP|rcsb pdb:6CG1|rcsb pdb:6CG2|rcsb pdb:6G5W|rcsb pdb:6G5X|rcsb pdb:6H4O|rcsb pdb:6H4P|rcsb pdb:6H4Q|rcsb pdb:6H4R|rcsb pdb:6H4S|rcsb pdb:6H4T|rcsb pdb:6H4U|rcsb pdb:6H4V|rcsb pdb:6H4W|rcsb pdb:6H4X|rcsb pdb:6H4Y|rcsb pdb:6H8P|rcsb pdb:6HGT|rcsb pdb:7D4A|reactome:R-HSA-3214842|reactome:R-HSA-5693565|reactome:R-HSA-9029569 refseq:NP_000036.2|refseq:NP_001231367.1|ensembl:ENSG00000118520(gene)|ensembl:ENST00000368087(transcript)|go:"GO:0000050"(urea cycle)|go:"GO:0001889"(liver development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004053"(arginase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006527"(arginine catabolic process)|go:"GO:0007568"(aging)|go:"GO:0009635"(response to herbicide)|go:"GO:0010042"(response to manganese ion)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010963"|go:"GO:0014075"(response to amine)|go:"GO:0019547"(arginine catabolic process to ornithine)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030324"(lung development)|go:"GO:0032964"(collagen biosynthetic process)|go:"GO:0033189"(response to vitamin A)|go:"GO:0033197"(response to vitamin E)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043200"(response to amino acid)|go:"GO:0045087"(innate immune response)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048678"(response to axon injury)|go:"GO:0051597"(response to methylmercury)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070965"(positive regulation of neutrophil mediated killing of fungus)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071377"(cellular response to glucagon stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:2000552"(negative regulation of T-helper 2 cell cytokine production)|interpro:IPR006035(Ureohydrolase)|interpro:IPR014033(Arginase, subgroup)|go:"GO:0060056"(mammary gland involution)|interpro:IPR020855|interpro:IPR023696|mint:P05089|rcsb pdb:1WVA|rcsb pdb:1WVB|rcsb pdb:2AEB|rcsb pdb:2PHA|rcsb pdb:2PHO|rcsb pdb:2PLL|rcsb pdb:2ZAV|rcsb pdb:3DJ8|rcsb pdb:3E6K|rcsb pdb:3E6V|rcsb pdb:3F80|rcsb pdb:3GMZ|rcsb pdb:3GN0|rcsb pdb:3KV2|rcsb pdb:3LP4|rcsb pdb:3LP7|rcsb pdb:3MFV|rcsb pdb:3MFW|rcsb pdb:3MJL|rcsb pdb:3SJT|rcsb pdb:3SKK|rcsb pdb:3TF3|rcsb pdb:3TH7|rcsb pdb:3THE|rcsb pdb:3THH|rcsb pdb:3THJ|rcsb pdb:4FCI|rcsb pdb:4FCK|rcsb pdb:4GSM|rcsb pdb:4GSV|rcsb pdb:4GSZ|rcsb pdb:4GWC|rcsb pdb:4GWD|rcsb pdb:4HWW|rcsb pdb:4HXQ|rcsb pdb:4IE1|rcsb pdb:6Q92|rcsb pdb:6Q9P|rcsb pdb:6QAF|rcsb pdb:6V7C|rcsb pdb:6V7D|rcsb pdb:6V7E|rcsb pdb:6V7F|reactome:R-HSA-6798695|reactome:R-HSA-70635 - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:P8atv/4zKIc7bVg3IZYlw5gVIHY9606 rogid:b8HHscDekWZdN1S4OxFTA6rjvn89606 rigid:mjFSsqMcLkXX1ecO3bZymOEf+cw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75164 uniprotkb:P01040 intact:EBI-936709|uniprotkb:Q5VVB1|ensembl:ENSP00000361473 intact:EBI-724303|ensembl:ENSP00000264474|uniprotkb:Q6IB90 psi-mi:kdm4a_human(display_long)|uniprotkb:KDM4A(gene name)|psi-mi:KDM4A(display_short)|uniprotkb:JMJD2(gene name synonym)|uniprotkb:KIAA0677(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2A(gene name synonym)|uniprotkb:JHDM3A(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(36) demethylase 4A"(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4A"(gene name synonym)|uniprotkb:JMJD2A(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3A(gene name synonym) psi-mi:cyta_human(display_long)|uniprotkb:Cystatin-AS(gene name synonym)|uniprotkb:Stefin-A(gene name synonym)|uniprotkb:CSTA(gene name)|psi-mi:CSTA(display_short)|uniprotkb:STF1(gene name synonym)|uniprotkb:STFA(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479882|imex:IM-26985-331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055478.2|refseq:XP_005271411.1|refseq:XP_005271412.1|dip:DIP-29372N|ensembl:ENSG00000066135(gene)|ensembl:ENST00000372396(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016577"(histone demethylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:O75164|rcsb pdb:2GF7|rcsb pdb:2GFA|rcsb pdb:2GP3|rcsb pdb:2GP5|rcsb pdb:2OQ6|rcsb pdb:2OQ7|rcsb pdb:2OS2|rcsb pdb:2OT7|rcsb pdb:2OX0|rcsb pdb:2P5B|rcsb pdb:2PXJ|rcsb pdb:2Q8C|rcsb pdb:2Q8D|rcsb pdb:2Q8E|rcsb pdb:2QQR|rcsb pdb:2QQS|rcsb pdb:2VD7|rcsb pdb:2WWJ|rcsb pdb:2YBK|rcsb pdb:2YBP|rcsb pdb:2YBS|rcsb pdb:3NJY|rcsb pdb:3PDQ|rcsb pdb:3RVH|rcsb pdb:3U4S|rcsb pdb:4AI9|rcsb pdb:4BIS|rcsb pdb:4GD4|rcsb pdb:4URA|rcsb pdb:4V2V|rcsb pdb:4V2W|rcsb pdb:5A7N|rcsb pdb:5A7O|rcsb pdb:5A7P|rcsb pdb:5A7Q|rcsb pdb:5A7S|rcsb pdb:5A7W|rcsb pdb:5A80|rcsb pdb:5ANQ|rcsb pdb:5D6W|rcsb pdb:5D6X|rcsb pdb:5D6Y|rcsb pdb:5F2S|rcsb pdb:5F2W|rcsb pdb:5F32|rcsb pdb:5F37|rcsb pdb:5F39|rcsb pdb:5F3C|rcsb pdb:5F3E|rcsb pdb:5F3G|rcsb pdb:5F3I|rcsb pdb:5F5I|rcsb pdb:5FPV|rcsb pdb:5FWE|rcsb pdb:5FY8|rcsb pdb:5FYC|rcsb pdb:5FYH|rcsb pdb:5FYI|rcsb pdb:5LY1|rcsb pdb:5LY2|rcsb pdb:5TVR|rcsb pdb:5TVS|rcsb pdb:5VAR|rcsb pdb:5VGI|rcsb pdb:5VMP|rcsb pdb:6CG1|rcsb pdb:6CG2|rcsb pdb:6G5W|rcsb pdb:6G5X|rcsb pdb:6H4O|rcsb pdb:6H4P|rcsb pdb:6H4Q|rcsb pdb:6H4R|rcsb pdb:6H4S|rcsb pdb:6H4T|rcsb pdb:6H4U|rcsb pdb:6H4V|rcsb pdb:6H4W|rcsb pdb:6H4X|rcsb pdb:6H4Y|rcsb pdb:6H8P|rcsb pdb:6HGT|rcsb pdb:7D4A|reactome:R-HSA-3214842|reactome:R-HSA-5693565|reactome:R-HSA-9029569 refseq:NP_005204.1|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR001713(Proteinase inhibitor I25A, stefin A)|mint:P01040|rcsb pdb:1CYU|rcsb pdb:1CYV|rcsb pdb:1DVC|rcsb pdb:1DVD|rcsb pdb:1GD3|rcsb pdb:1GD4|rcsb pdb:1N9J|rcsb pdb:1NB3|rcsb pdb:1NB5|rcsb pdb:3K9M|rcsb pdb:3KFQ|interpro:IPR018073|rcsb pdb:3KSE|reactome:R-HSA-6809371|ensembl:ENSG00000121552(gene)|ensembl:ENST00000264474(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002020"(protease binding)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0045861"(negative regulation of proteolysis) - - comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:P8atv/4zKIc7bVg3IZYlw5gVIHY9606 rogid:SzbpyWUHlOtItIvffzuwhcqFsDI9606 rigid:mjFSsqMcLkXX1ecO3bZymOEf+cw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75164 uniprotkb:P06702 intact:EBI-936709|uniprotkb:Q5VVB1|ensembl:ENSP00000361473 intact:EBI-1055001|uniprotkb:Q6FGA1|uniprotkb:Q9NYM0|uniprotkb:Q9UCJ1|uniprotkb:D3DV36|ensembl:ENSP00000357727 psi-mi:kdm4a_human(display_long)|uniprotkb:KDM4A(gene name)|psi-mi:KDM4A(display_short)|uniprotkb:JMJD2(gene name synonym)|uniprotkb:KIAA0677(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2A(gene name synonym)|uniprotkb:JHDM3A(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(36) demethylase 4A"(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4A"(gene name synonym)|uniprotkb:JMJD2A(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3A(gene name synonym) psi-mi:s10a9_human(display_long)|uniprotkb:S100 calcium-binding protein A9(gene name synonym)|uniprotkb:Calgranulin-B(gene name synonym)|uniprotkb:Migration inhibitory factor-related protein 14(gene name synonym)|uniprotkb:Leukocyte L1 complex heavy chain(gene name synonym)|uniprotkb:Calprotectin L1H subunit(gene name synonym)|uniprotkb:S100A9(gene name)|psi-mi:S100A9(display_short)|uniprotkb:CAGB(gene name synonym)|uniprotkb:CFAG(gene name synonym)|uniprotkb:MRP14(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479882|imex:IM-26985-331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055478.2|refseq:XP_005271411.1|refseq:XP_005271412.1|dip:DIP-29372N|ensembl:ENSG00000066135(gene)|ensembl:ENST00000372396(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016577"(histone demethylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:O75164|rcsb pdb:2GF7|rcsb pdb:2GFA|rcsb pdb:2GP3|rcsb pdb:2GP5|rcsb pdb:2OQ6|rcsb pdb:2OQ7|rcsb pdb:2OS2|rcsb pdb:2OT7|rcsb pdb:2OX0|rcsb pdb:2P5B|rcsb pdb:2PXJ|rcsb pdb:2Q8C|rcsb pdb:2Q8D|rcsb pdb:2Q8E|rcsb pdb:2QQR|rcsb pdb:2QQS|rcsb pdb:2VD7|rcsb pdb:2WWJ|rcsb pdb:2YBK|rcsb pdb:2YBP|rcsb pdb:2YBS|rcsb pdb:3NJY|rcsb pdb:3PDQ|rcsb pdb:3RVH|rcsb pdb:3U4S|rcsb pdb:4AI9|rcsb pdb:4BIS|rcsb pdb:4GD4|rcsb pdb:4URA|rcsb pdb:4V2V|rcsb pdb:4V2W|rcsb pdb:5A7N|rcsb pdb:5A7O|rcsb pdb:5A7P|rcsb pdb:5A7Q|rcsb pdb:5A7S|rcsb pdb:5A7W|rcsb pdb:5A80|rcsb pdb:5ANQ|rcsb pdb:5D6W|rcsb pdb:5D6X|rcsb pdb:5D6Y|rcsb pdb:5F2S|rcsb pdb:5F2W|rcsb pdb:5F32|rcsb pdb:5F37|rcsb pdb:5F39|rcsb pdb:5F3C|rcsb pdb:5F3E|rcsb pdb:5F3G|rcsb pdb:5F3I|rcsb pdb:5F5I|rcsb pdb:5FPV|rcsb pdb:5FWE|rcsb pdb:5FY8|rcsb pdb:5FYC|rcsb pdb:5FYH|rcsb pdb:5FYI|rcsb pdb:5LY1|rcsb pdb:5LY2|rcsb pdb:5TVR|rcsb pdb:5TVS|rcsb pdb:5VAR|rcsb pdb:5VGI|rcsb pdb:5VMP|rcsb pdb:6CG1|rcsb pdb:6CG2|rcsb pdb:6G5W|rcsb pdb:6G5X|rcsb pdb:6H4O|rcsb pdb:6H4P|rcsb pdb:6H4Q|rcsb pdb:6H4R|rcsb pdb:6H4S|rcsb pdb:6H4T|rcsb pdb:6H4U|rcsb pdb:6H4V|rcsb pdb:6H4W|rcsb pdb:6H4X|rcsb pdb:6H4Y|rcsb pdb:6H8P|rcsb pdb:6HGT|rcsb pdb:7D4A|reactome:R-HSA-3214842|reactome:R-HSA-5693565|reactome:R-HSA-9029569 refseq:NP_002956.1|rcsb pdb:1XK4|rcsb pdb:4GGF|rcsb pdb:4XJK|rcsb pdb:5I8N|rcsb pdb:5W1F|rcsb pdb:6DS2|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5668599|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-6799990|ensembl:ENSG00000163220(gene)|ensembl:ENST00000368738(transcript)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035662"(Toll-like receptor 4 binding)|go:"GO:0035821"(modulation of process of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0045113"(regulation of integrin biosynthetic process)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070488"(neutrophil aggregation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|mint:P06702|rcsb pdb:1IRJ|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016209"(antioxidant activity)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0030054"(cell junction)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032119"(sequestering of zinc ion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035425"(autocrine signaling)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|dip:DIP-1166N - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:P8atv/4zKIc7bVg3IZYlw5gVIHY9606 rogid:IGnX4DSnv8xMr5pY4T7X7vYos5A9606 rigid:mjFSsqMcLkXX1ecO3bZymOEf+cw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75164 uniprotkb:P22528 intact:EBI-936709|uniprotkb:Q5VVB1|ensembl:ENSP00000361473 intact:EBI-1058892|ensembl:ENSP00000306461|uniprotkb:B2R5H7|uniprotkb:P22529|uniprotkb:P22530|uniprotkb:Q5T524 psi-mi:kdm4a_human(display_long)|uniprotkb:KDM4A(gene name)|psi-mi:KDM4A(display_short)|uniprotkb:JMJD2(gene name synonym)|uniprotkb:KIAA0677(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2A(gene name synonym)|uniprotkb:JHDM3A(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(36) demethylase 4A"(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4A"(gene name synonym)|uniprotkb:JMJD2A(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3A(gene name synonym) psi-mi:spr1b_human(display_long)|uniprotkb:SPRR1B(gene name)|psi-mi:SPRR1B(display_short)|uniprotkb:Small proline-rich protein IB(gene name synonym)|uniprotkb:14.9 kDa pancornulin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479882|imex:IM-26985-331 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055478.2|refseq:XP_005271411.1|refseq:XP_005271412.1|dip:DIP-29372N|ensembl:ENSG00000066135(gene)|ensembl:ENST00000372396(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016577"(histone demethylation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048712"(negative regulation of astrocyte differentiation)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|mint:O75164|rcsb pdb:2GF7|rcsb pdb:2GFA|rcsb pdb:2GP3|rcsb pdb:2GP5|rcsb pdb:2OQ6|rcsb pdb:2OQ7|rcsb pdb:2OS2|rcsb pdb:2OT7|rcsb pdb:2OX0|rcsb pdb:2P5B|rcsb pdb:2PXJ|rcsb pdb:2Q8C|rcsb pdb:2Q8D|rcsb pdb:2Q8E|rcsb pdb:2QQR|rcsb pdb:2QQS|rcsb pdb:2VD7|rcsb pdb:2WWJ|rcsb pdb:2YBK|rcsb pdb:2YBP|rcsb pdb:2YBS|rcsb pdb:3NJY|rcsb pdb:3PDQ|rcsb pdb:3RVH|rcsb pdb:3U4S|rcsb pdb:4AI9|rcsb pdb:4BIS|rcsb pdb:4GD4|rcsb pdb:4URA|rcsb pdb:4V2V|rcsb pdb:4V2W|rcsb pdb:5A7N|rcsb pdb:5A7O|rcsb pdb:5A7P|rcsb pdb:5A7Q|rcsb pdb:5A7S|rcsb pdb:5A7W|rcsb pdb:5A80|rcsb pdb:5ANQ|rcsb pdb:5D6W|rcsb pdb:5D6X|rcsb pdb:5D6Y|rcsb pdb:5F2S|rcsb pdb:5F2W|rcsb pdb:5F32|rcsb pdb:5F37|rcsb pdb:5F39|rcsb pdb:5F3C|rcsb pdb:5F3E|rcsb pdb:5F3G|rcsb pdb:5F3I|rcsb pdb:5F5I|rcsb pdb:5FPV|rcsb pdb:5FWE|rcsb pdb:5FY8|rcsb pdb:5FYC|rcsb pdb:5FYH|rcsb pdb:5FYI|rcsb pdb:5LY1|rcsb pdb:5LY2|rcsb pdb:5TVR|rcsb pdb:5TVS|rcsb pdb:5VAR|rcsb pdb:5VGI|rcsb pdb:5VMP|rcsb pdb:6CG1|rcsb pdb:6CG2|rcsb pdb:6G5W|rcsb pdb:6G5X|rcsb pdb:6H4O|rcsb pdb:6H4P|rcsb pdb:6H4Q|rcsb pdb:6H4R|rcsb pdb:6H4S|rcsb pdb:6H4T|rcsb pdb:6H4U|rcsb pdb:6H4V|rcsb pdb:6H4W|rcsb pdb:6H4X|rcsb pdb:6H4Y|rcsb pdb:6H8P|rcsb pdb:6HGT|rcsb pdb:7D4A|reactome:R-HSA-3214842|reactome:R-HSA-5693565|reactome:R-HSA-9029569 ensembl:ENSG00000169469(gene)|ensembl:ENST00000307098(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0031424"(keratinization)|interpro:IPR003302("Cornifin (SPRR)")|mint:P22528|reactome:R-HSA-6809371|refseq:NP_003116.2 - - comment:"author score: 31" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:P8atv/4zKIc7bVg3IZYlw5gVIHY9606 rogid:WU0vu+DHdIJm0x40HdcpAdJgdgo9606 rigid:mjFSsqMcLkXX1ecO3bZymOEf+cw false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94953 uniprotkb:Q96S55 intact:EBI-725902|uniprotkb:Q6P3R5|uniprotkb:Q9P1V1|uniprotkb:O75274|uniprotkb:Q9UF40|uniprotkb:B9EGN8|uniprotkb:D6W631 intact:EBI-2513471|ensembl:ENSP00000370150|ensembl:ENSP00000477551|uniprotkb:Q9NRJ6|uniprotkb:Q5W0E2|uniprotkb:Q53EP6|uniprotkb:Q8WV26|uniprotkb:Q5W0E4|uniprotkb:Q59ET8|uniprotkb:Q9H681|uniprotkb:B2RDB0 psi-mi:kdm4b_human(display_long)|uniprotkb:Jumonji domain-containing protein 2B(gene name synonym)|uniprotkb:KDM4B(gene name)|psi-mi:KDM4B(display_short)|uniprotkb:KIAA0876(gene name synonym)|uniprotkb:JHDM3B(gene name synonym)|uniprotkb:JMJD2B(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3B(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4B"(gene name synonym) psi-mi:wrip1_human(display_long)|uniprotkb:WRNIP1(gene name)|psi-mi:WRNIP1(display_short)|uniprotkb:WHIP(gene name synonym)|uniprotkb:Werner helicase-interacting protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479942|imex:IM-26985-175 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055830.1|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|rcsb pdb:4LXL|rcsb pdb:4UC4|reactome:R-HSA-3214842|reactome:R-HSA-5693565|reactome:R-HSA-9018519|dip:DIP-47283N|mint:O94953 ensembl:ENSG00000124535(gene)|ensembl:ENST00000380773(transcript)|ensembl:ENST00000618555(transcript)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR006642(Zinc finger, Rad18-type putative)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR021886|interpro:IPR027417|interpro:IPR032423|interpro:IPR040539|mint:Q96S55|rcsb pdb:3VHS|rcsb pdb:3VHT|go:"GO:0017116"(single-stranded DNA helicase activity)|refseq:NP_064520.2|refseq:NP_569079.1 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yU+kv4zyhtwFSzNUEDvgKsSNkVE9606 rogid:Q8qVSqItgTO7sbWGAQ3XAoFFUr89606 rigid:aXvEkLZMYVpCBkUON5atFjIBny4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94953 uniprotkb:O95816 intact:EBI-725902|uniprotkb:Q6P3R5|uniprotkb:Q9P1V1|uniprotkb:O75274|uniprotkb:Q9UF40|uniprotkb:B9EGN8|uniprotkb:D6W631 intact:EBI-355275|uniprotkb:Q08AS9|uniprotkb:Q6FID0|uniprotkb:B4DXE2|ensembl:ENSP00000359727|intact:EBI-11068407 psi-mi:kdm4b_human(display_long)|uniprotkb:Jumonji domain-containing protein 2B(gene name synonym)|uniprotkb:KDM4B(gene name)|psi-mi:KDM4B(display_short)|uniprotkb:KIAA0876(gene name synonym)|uniprotkb:JHDM3B(gene name synonym)|uniprotkb:JMJD2B(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3B(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4B"(gene name synonym) psi-mi:bag2_human(display_long)|uniprotkb:BAG2(gene name)|psi-mi:BAG2(display_short)|uniprotkb:Bcl-2-associated athanogene 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479942|imex:IM-26985-175 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055830.1|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|rcsb pdb:4LXL|rcsb pdb:4UC4|reactome:R-HSA-3214842|reactome:R-HSA-5693565|reactome:R-HSA-9018519|dip:DIP-47283N|mint:O94953 refseq:NP_004273.1|refseq:XP_011513301.1|refseq:XP_005249547.1|ensembl:ENSG00000112208(gene)|ensembl:ENST00000370693(transcript)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0019538"(protein metabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1901588"(dendritic microtubule)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|mint:O95816|reactome:R-HSA-3371453|refseq:XP_011513300.1 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yU+kv4zyhtwFSzNUEDvgKsSNkVE9606 rogid:nBGGBIQc/3P0mwp7N/XuTGLOrg89606 rigid:aXvEkLZMYVpCBkUON5atFjIBny4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94953 uniprotkb:P78371 intact:EBI-725902|uniprotkb:Q6P3R5|uniprotkb:Q9P1V1|uniprotkb:O75274|uniprotkb:Q9UF40|uniprotkb:B9EGN8|uniprotkb:D6W631 intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300 psi-mi:kdm4b_human(display_long)|uniprotkb:Jumonji domain-containing protein 2B(gene name synonym)|uniprotkb:KDM4B(gene name)|psi-mi:KDM4B(display_short)|uniprotkb:KIAA0876(gene name synonym)|uniprotkb:JHDM3B(gene name synonym)|uniprotkb:JMJD2B(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3B(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4B"(gene name synonym) psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479942|imex:IM-26985-175 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055830.1|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|rcsb pdb:4LXL|rcsb pdb:4UC4|reactome:R-HSA-3214842|reactome:R-HSA-5693565|reactome:R-HSA-9018519|dip:DIP-47283N|mint:O94953 refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yU+kv4zyhtwFSzNUEDvgKsSNkVE9606 rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606 rigid:aXvEkLZMYVpCBkUON5atFjIBny4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94953 uniprotkb:P48643 intact:EBI-725902|uniprotkb:Q6P3R5|uniprotkb:Q9P1V1|uniprotkb:O75274|uniprotkb:Q9UF40|uniprotkb:B9EGN8|uniprotkb:D6W631 intact:EBI-355710|uniprotkb:A8JZY8|ensembl:ENSP00000280326|uniprotkb:A8K2X8|uniprotkb:B4DYD8 psi-mi:kdm4b_human(display_long)|uniprotkb:Jumonji domain-containing protein 2B(gene name synonym)|uniprotkb:KDM4B(gene name)|psi-mi:KDM4B(display_short)|uniprotkb:KIAA0876(gene name synonym)|uniprotkb:JHDM3B(gene name synonym)|uniprotkb:JMJD2B(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3B(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4B"(gene name synonym) psi-mi:tcpe_human(display_long)|uniprotkb:CCT5(gene name)|psi-mi:CCT5(display_short)|uniprotkb:CCTE(gene name synonym)|uniprotkb:KIAA0098(gene name synonym)|uniprotkb:CCT-epsilon(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479942|imex:IM-26985-175 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055830.1|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|rcsb pdb:4LXL|rcsb pdb:4UC4|reactome:R-HSA-3214842|reactome:R-HSA-5693565|reactome:R-HSA-9018519|dip:DIP-47283N|mint:O94953 refseq:NP_036205.1|ensembl:ENSG00000150753(gene)|ensembl:ENST00000280326(transcript)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|refseq:NP_001293084.1|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0009615"(response to virus)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0031681"(G-protein beta-subunit binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P48643|rcsb pdb:5UYX|rcsb pdb:5UYZ|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR012718(T-complex protein 1, epsilon subunit)|dip:DIP-31181N - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yU+kv4zyhtwFSzNUEDvgKsSNkVE9606 rogid:u7uFkOYrDKL0gGvC24p34tQHhcw9606 rigid:aXvEkLZMYVpCBkUON5atFjIBny4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94953 uniprotkb:Q9UNE7 intact:EBI-725902|uniprotkb:Q6P3R5|uniprotkb:Q9P1V1|uniprotkb:O75274|uniprotkb:Q9UF40|uniprotkb:B9EGN8|uniprotkb:D6W631 intact:EBI-357085|uniprotkb:O60526|uniprotkb:Q969U2|uniprotkb:Q9HBT1|uniprotkb:A2IDB9|ensembl:ENSP00000219548 psi-mi:kdm4b_human(display_long)|uniprotkb:Jumonji domain-containing protein 2B(gene name synonym)|uniprotkb:KDM4B(gene name)|psi-mi:KDM4B(display_short)|uniprotkb:KIAA0876(gene name synonym)|uniprotkb:JHDM3B(gene name synonym)|uniprotkb:JMJD2B(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3B(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4B"(gene name synonym) psi-mi:chip_human(display_long)|uniprotkb:CHIP(gene name synonym)|uniprotkb:STUB1(gene name)|psi-mi:STUB1(display_short)|uniprotkb:PP1131(orf name)|uniprotkb:Carboxy terminus of Hsp70-interacting protein(gene name synonym)|uniprotkb:STIP1 homology and U box-containing protein 1(gene name synonym)|uniprotkb:CLL-associated antigen KW-8(gene name synonym)|uniprotkb:Antigen NY-CO-7(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CHIP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479942|imex:IM-26985-175 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055830.1|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|rcsb pdb:4LXL|rcsb pdb:4UC4|reactome:R-HSA-3214842|reactome:R-HSA-5693565|reactome:R-HSA-9018519|dip:DIP-47283N|mint:O94953 dip:DIP-29752N|refseq:NP_005852.2|refseq:NP_001280126.1|ensembl:ENSG00000103266(gene)|ensembl:ENST00000219548(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031943"(regulation of glucocorticoid metabolic process)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046332"(SMAD binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0030579"(ubiquitin-dependent SMAD protein catabolic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090035"(positive regulation of chaperone-mediated protein complex assembly)|go:"GO:0101031"(chaperone complex)|interpro:IPR003613(U box)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019734|interpro:IPR041312|mint:Q9UNE7|rcsb pdb:4KBQ|rcsb pdb:6EFK|rcsb pdb:6NSV|reactome:R-HSA-2173788|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-8863795|reactome:R-HSA-8939902|reactome:R-HSA-8948751|reactome:R-HSA-983168 - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yU+kv4zyhtwFSzNUEDvgKsSNkVE9606 rogid:h4QyIM0TptgkQppPUgiKn68XjP49606 rigid:aXvEkLZMYVpCBkUON5atFjIBny4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94953 uniprotkb:P40227 intact:EBI-725902|uniprotkb:Q6P3R5|uniprotkb:Q9P1V1|uniprotkb:O75274|uniprotkb:Q9UF40|uniprotkb:B9EGN8|uniprotkb:D6W631 intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2 psi-mi:kdm4b_human(display_long)|uniprotkb:Jumonji domain-containing protein 2B(gene name synonym)|uniprotkb:KDM4B(gene name)|psi-mi:KDM4B(display_short)|uniprotkb:KIAA0876(gene name synonym)|uniprotkb:JHDM3B(gene name synonym)|uniprotkb:JMJD2B(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3B(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4B"(gene name synonym) psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479942|imex:IM-26985-175 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055830.1|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|rcsb pdb:4LXL|rcsb pdb:4UC4|reactome:R-HSA-3214842|reactome:R-HSA-5693565|reactome:R-HSA-9018519|dip:DIP-47283N|mint:O94953 refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yU+kv4zyhtwFSzNUEDvgKsSNkVE9606 rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606 rigid:aXvEkLZMYVpCBkUON5atFjIBny4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94953 uniprotkb:P50991 intact:EBI-725902|uniprotkb:Q6P3R5|uniprotkb:Q9P1V1|uniprotkb:O75274|uniprotkb:Q9UF40|uniprotkb:B9EGN8|uniprotkb:D6W631 intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958 psi-mi:kdm4b_human(display_long)|uniprotkb:Jumonji domain-containing protein 2B(gene name synonym)|uniprotkb:KDM4B(gene name)|psi-mi:KDM4B(display_short)|uniprotkb:KIAA0876(gene name synonym)|uniprotkb:JHDM3B(gene name synonym)|uniprotkb:JMJD2B(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3B(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4B"(gene name synonym) psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479942|imex:IM-26985-175 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055830.1|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|rcsb pdb:4LXL|rcsb pdb:4UC4|reactome:R-HSA-3214842|reactome:R-HSA-5693565|reactome:R-HSA-9018519|dip:DIP-47283N|mint:O94953 refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998 - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yU+kv4zyhtwFSzNUEDvgKsSNkVE9606 rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606 rigid:aXvEkLZMYVpCBkUON5atFjIBny4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94953 uniprotkb:P49368 intact:EBI-725902|uniprotkb:Q6P3R5|uniprotkb:Q9P1V1|uniprotkb:O75274|uniprotkb:Q9UF40|uniprotkb:B9EGN8|uniprotkb:D6W631 intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688 psi-mi:kdm4b_human(display_long)|uniprotkb:Jumonji domain-containing protein 2B(gene name synonym)|uniprotkb:KDM4B(gene name)|psi-mi:KDM4B(display_short)|uniprotkb:KIAA0876(gene name synonym)|uniprotkb:JHDM3B(gene name synonym)|uniprotkb:JMJD2B(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3B(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4B"(gene name synonym) psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479942|imex:IM-26985-175 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055830.1|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|rcsb pdb:4LXL|rcsb pdb:4UC4|reactome:R-HSA-3214842|reactome:R-HSA-5693565|reactome:R-HSA-9018519|dip:DIP-47283N|mint:O94953 refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yU+kv4zyhtwFSzNUEDvgKsSNkVE9606 rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606 rigid:aXvEkLZMYVpCBkUON5atFjIBny4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94953 uniprotkb:P50990 intact:EBI-725902|uniprotkb:Q6P3R5|uniprotkb:Q9P1V1|uniprotkb:O75274|uniprotkb:Q9UF40|uniprotkb:B9EGN8|uniprotkb:D6W631 intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788 psi-mi:kdm4b_human(display_long)|uniprotkb:Jumonji domain-containing protein 2B(gene name synonym)|uniprotkb:KDM4B(gene name)|psi-mi:KDM4B(display_short)|uniprotkb:KIAA0876(gene name synonym)|uniprotkb:JHDM3B(gene name synonym)|uniprotkb:JMJD2B(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3B(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4B"(gene name synonym) psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479942|imex:IM-26985-175 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055830.1|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|rcsb pdb:4LXL|rcsb pdb:4UC4|reactome:R-HSA-3214842|reactome:R-HSA-5693565|reactome:R-HSA-9018519|dip:DIP-47283N|mint:O94953 refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N - - comment:"author score: 27" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yU+kv4zyhtwFSzNUEDvgKsSNkVE9606 rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606 rigid:aXvEkLZMYVpCBkUON5atFjIBny4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94953 uniprotkb:Q99832 intact:EBI-725902|uniprotkb:Q6P3R5|uniprotkb:Q9P1V1|uniprotkb:O75274|uniprotkb:Q9UF40|uniprotkb:B9EGN8|uniprotkb:D6W631 intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091 psi-mi:kdm4b_human(display_long)|uniprotkb:Jumonji domain-containing protein 2B(gene name synonym)|uniprotkb:KDM4B(gene name)|psi-mi:KDM4B(display_short)|uniprotkb:KIAA0876(gene name synonym)|uniprotkb:JHDM3B(gene name synonym)|uniprotkb:JMJD2B(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3B(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4B"(gene name synonym) psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25479942|imex:IM-26985-175 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055830.1|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|interpro:IPR040477|rcsb pdb:4LXL|rcsb pdb:4UC4|reactome:R-HSA-3214842|reactome:R-HSA-5693565|reactome:R-HSA-9018519|dip:DIP-47283N|mint:O94953 dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422 - - comment:"author score: 29" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yU+kv4zyhtwFSzNUEDvgKsSNkVE9606 rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606 rigid:aXvEkLZMYVpCBkUON5atFjIBny4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15550 uniprotkb:P07477 intact:EBI-4292203|uniprotkb:Q52LL9|uniprotkb:Q5JVQ7|intact:EBI-28988602|ensembl:ENSP00000367203 intact:EBI-1222902|uniprotkb:A6NJ71|uniprotkb:Q92955|uniprotkb:Q9HAN4|uniprotkb:Q9HAN5|uniprotkb:Q9HAN6|uniprotkb:Q9HAN7|intact:EBI-1760472|intact:EBI-1965533|uniprotkb:A1A509|uniprotkb:Q5NV57|uniprotkb:Q7M4N3|uniprotkb:Q7M4N4|uniprotkb:B2R5I5|ensembl:ENSP00000308720|ensembl:ENSP00000479217 psi-mi:kdm6a_human(display_long)|uniprotkb:KDM6A(gene name)|psi-mi:KDM6A(display_short)|uniprotkb:UTX(gene name synonym)|uniprotkb:Histone demethylase UTX(gene name synonym)|uniprotkb:Ubiquitously-transcribed TPR protein on the X chromosome(gene name synonym)|uniprotkb:Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(27) demethylase 6A"(gene name synonym) psi-mi:try1_human(display_long)|uniprotkb:PRSS1(gene name)|psi-mi:PRSS1(display_short)|uniprotkb:TRP1(gene name synonym)|uniprotkb:TRY1(gene name synonym)|uniprotkb:TRYP1(gene name synonym)|uniprotkb:Trypsin I(gene name synonym)|uniprotkb:Cationic trypsinogen(gene name synonym)|uniprotkb:Serine protease 1(gene name synonym)|uniprotkb:Beta-trypsin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480275|imex:IM-26985-411 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066963.2|ensembl:ENSG00000147050(gene)|ensembl:ENST00000377967(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007507"(heart development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071557"(histone H3-K27 demethylation)|go:"GO:0071558"(histone H3-tri/di-methyl-lysine-27 demethylase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:O15550|rcsb pdb:3AVR|rcsb pdb:3AVS|rcsb pdb:6FUK|rcsb pdb:6FUL|reactome:R-HSA-3214842|reactome:R-HSA-5617472|ensembl:ENSP00000367203|dip:DIP-46192N refseq:NP_002760.1|ensembl:ENSG00000204983(gene)|ensembl:ENSG00000274247(gene)|ensembl:ENST00000311737(transcript)|ensembl:ENST00000616256(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0007586"(digestion)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0072562"(blood microparticle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|mint:P07477|rcsb pdb:1FXY|rcsb pdb:1TRN|rcsb pdb:2RA3|rcsb pdb:4WWY|rcsb pdb:4WXV|reactome:R-HSA-1592389|reactome:R-HSA-196741 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:sqg+Ikkgvz0uT/gMx1wYs9FaDbI9606 rogid:2elS/qMYj0sflxilyWfk3KPtGmo9606 rigid:3jKUwGPTqQkRtkasNXUKq3Z6LlA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15550 uniprotkb:P68363 intact:EBI-4292203|uniprotkb:Q52LL9|uniprotkb:Q5JVQ7|intact:EBI-28988602|ensembl:ENSP00000367203 intact:EBI-487083|intact:EBI-1384226|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:Q27I68|ensembl:ENSP00000336799|uniprotkb:Q8WU19 psi-mi:kdm6a_human(display_long)|uniprotkb:KDM6A(gene name)|psi-mi:KDM6A(display_short)|uniprotkb:UTX(gene name synonym)|uniprotkb:Histone demethylase UTX(gene name synonym)|uniprotkb:Ubiquitously-transcribed TPR protein on the X chromosome(gene name synonym)|uniprotkb:Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(27) demethylase 6A"(gene name synonym) psi-mi:tba1b_human(display_long)|uniprotkb:TUBA1B(gene name)|psi-mi:TUBA1B(display_short)|uniprotkb:Tubulin alpha-ubiquitous chain(gene name synonym)|uniprotkb:Alpha-tubulin ubiquitous(gene name synonym)|uniprotkb:Tubulin K-alpha-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480275|imex:IM-26985-411 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066963.2|ensembl:ENSG00000147050(gene)|ensembl:ENST00000377967(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007507"(heart development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071557"(histone H3-K27 demethylation)|go:"GO:0071558"(histone H3-tri/di-methyl-lysine-27 demethylase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:O15550|rcsb pdb:3AVR|rcsb pdb:3AVS|rcsb pdb:6FUK|rcsb pdb:6FUL|reactome:R-HSA-3214842|reactome:R-HSA-5617472|ensembl:ENSP00000367203|dip:DIP-46192N refseq:NP_006073.2|ensembl:ENSG00000123416(gene)|ensembl:ENST00000336023(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-983189|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|go:"GO:0045121"(membrane raft)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68363|rcsb pdb:2E4H|rcsb pdb:5IJ0|rcsb pdb:5IJ9|rcsb pdb:5N5N|rcsb pdb:6E7B|rcsb pdb:6E7C|rcsb pdb:6I2I|go:"GO:0051301"(cell division)|rcsb pdb:6J4V|rcsb pdb:6J8O|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|rcsb pdb:6S8L|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9013407|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-2132295|reactome:R-HSA-9668328 - - comment:"author score: 43" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:sqg+Ikkgvz0uT/gMx1wYs9FaDbI9606 rogid:D4YpuLCXl/S+53qV7P7sF81aARY9606 rigid:3jKUwGPTqQkRtkasNXUKq3Z6LlA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15550 uniprotkb:Q9BTK6 intact:EBI-4292203|uniprotkb:Q52LL9|uniprotkb:Q5JVQ7|intact:EBI-28988602|ensembl:ENSP00000367203 intact:EBI-2372223|uniprotkb:A2ICR6|ensembl:ENSP00000326519 psi-mi:kdm6a_human(display_long)|uniprotkb:KDM6A(gene name)|psi-mi:KDM6A(display_short)|uniprotkb:UTX(gene name synonym)|uniprotkb:Histone demethylase UTX(gene name synonym)|uniprotkb:Ubiquitously-transcribed TPR protein on the X chromosome(gene name synonym)|uniprotkb:Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(27) demethylase 6A"(gene name synonym) psi-mi:pagr1_human(display_long)|uniprotkb:PAGR1(gene name)|psi-mi:PAGR1(display_short)|uniprotkb:C16orf53(gene name synonym)|uniprotkb:PA1(gene name synonym)|uniprotkb:PAXIP1-associated protein 1(gene name synonym)|uniprotkb:PTIP-associated protein 1(gene name synonym)|uniprotkb:Glutamate-rich coactivator interacting with SRC1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480275|imex:IM-26985-411 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066963.2|ensembl:ENSG00000147050(gene)|ensembl:ENST00000377967(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007507"(heart development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071557"(histone H3-K27 demethylation)|go:"GO:0071558"(histone H3-tri/di-methyl-lysine-27 demethylase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:O15550|rcsb pdb:3AVR|rcsb pdb:3AVS|rcsb pdb:6FUK|rcsb pdb:6FUL|reactome:R-HSA-3214842|reactome:R-HSA-5617472|ensembl:ENSP00000367203|dip:DIP-46192N refseq:NP_078792.1|ensembl:ENSG00000280789(gene)|ensembl:ENST00000320330(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR028213|mint:Q9BTK6|reactome:R-HSA-5617472 - - comment:"author score: 76" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:sqg+Ikkgvz0uT/gMx1wYs9FaDbI9606 rogid:9yYPNooDxUEqCQX/n3OUxtRnM9U9606 rigid:3jKUwGPTqQkRtkasNXUKq3Z6LlA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15550 uniprotkb:Q14686 intact:EBI-4292203|uniprotkb:Q52LL9|uniprotkb:Q5JVQ7|intact:EBI-28988602|ensembl:ENSP00000367203 intact:EBI-78670|uniprotkb:A6NLF1|uniprotkb:Q9NTZ9|uniprotkb:Q9UH74|uniprotkb:Q9UK86|ensembl:ENSP00000351894|ensembl:ENSP00000363929|uniprotkb:B2RMN5|uniprotkb:E1P5P7 psi-mi:kdm6a_human(display_long)|uniprotkb:KDM6A(gene name)|psi-mi:KDM6A(display_short)|uniprotkb:UTX(gene name synonym)|uniprotkb:Histone demethylase UTX(gene name synonym)|uniprotkb:Ubiquitously-transcribed TPR protein on the X chromosome(gene name synonym)|uniprotkb:Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(27) demethylase 6A"(gene name synonym) psi-mi:ncoa6_human(display_long)|uniprotkb:NCOA6(gene name)|psi-mi:NCOA6(display_short)|uniprotkb:KIAA0181(gene name synonym)|uniprotkb:RAP250(gene name synonym)|uniprotkb:Amplified in breast cancer protein 3(gene name synonym)|uniprotkb:Cancer-amplified transcriptional coactivator ASC-2(gene name synonym)|uniprotkb:Activating signal cointegrator 2(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-interacting protein(gene name synonym)|uniprotkb:Nuclear receptor-activating protein, 250 kDa(gene name synonym)|uniprotkb:Nuclear receptor coactivator RAP250(gene name synonym)|uniprotkb:Thyroid hormone receptor-binding protein(gene name synonym)|uniprotkb:AIB3(gene name synonym)|uniprotkb:TRBP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480275|imex:IM-26985-411 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066963.2|ensembl:ENSG00000147050(gene)|ensembl:ENST00000377967(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007507"(heart development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071557"(histone H3-K27 demethylation)|go:"GO:0071558"(histone H3-tri/di-methyl-lysine-27 demethylase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:O15550|rcsb pdb:3AVR|rcsb pdb:3AVS|rcsb pdb:6FUK|rcsb pdb:6FUL|reactome:R-HSA-3214842|reactome:R-HSA-5617472|ensembl:ENSP00000367203|dip:DIP-46192N refseq:NP_001229468.1|refseq:NP_054790.2|ensembl:ENSG00000198646(gene)|ensembl:ENST00000359003(transcript)|ensembl:ENST00000374796(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0009725"(response to hormone)|go:"GO:0019899"(enzyme binding)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051427"(hormone receptor binding)|interpro:IPR026638|interpro:IPR032715|mint:Q14686|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-5617472|reactome:R-HSA-9707564|reactome:R-HSA-9707616|ensembl:ENSP00000351894|ensembl:ENSP00000363929|refseq:NP_001305169.1|dip:DIP-30934N - - comment:"author score: 81" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:sqg+Ikkgvz0uT/gMx1wYs9FaDbI9606 rogid:0PZz93t/oHYDVeiX+8NqjSlpNRo9606 rigid:3jKUwGPTqQkRtkasNXUKq3Z6LlA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15550 uniprotkb:Q6ZW49 intact:EBI-4292203|uniprotkb:Q52LL9|uniprotkb:Q5JVQ7|intact:EBI-28988602|ensembl:ENSP00000367203 intact:EBI-743225|ensembl:ENSP00000380376|ensembl:ENSP00000384048|uniprotkb:O15404|uniprotkb:Q6N099|uniprotkb:Q6ZWH9|uniprotkb:Q7Z315|uniprotkb:Q86UN0|uniprotkb:Q8N4P9|uniprotkb:Q96HP2 psi-mi:kdm6a_human(display_long)|uniprotkb:KDM6A(gene name)|psi-mi:KDM6A(display_short)|uniprotkb:UTX(gene name synonym)|uniprotkb:Histone demethylase UTX(gene name synonym)|uniprotkb:Ubiquitously-transcribed TPR protein on the X chromosome(gene name synonym)|uniprotkb:Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(27) demethylase 6A"(gene name synonym) psi-mi:paxi1_human(display_long)|uniprotkb:PAX transactivation activation domain-interacting protein(gene name synonym)|uniprotkb:PAXIP1(gene name)|psi-mi:PAXIP1(display_short)|uniprotkb:PAXIP1L(gene name synonym)|uniprotkb:PTIP(gene name synonym)|uniprotkb:CAGF28(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480275|imex:IM-26985-411 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066963.2|ensembl:ENSG00000147050(gene)|ensembl:ENST00000377967(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007507"(heart development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071557"(histone H3-K27 demethylation)|go:"GO:0071558"(histone H3-tri/di-methyl-lysine-27 demethylase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:O15550|rcsb pdb:3AVR|rcsb pdb:3AVS|rcsb pdb:6FUK|rcsb pdb:6FUL|reactome:R-HSA-3214842|reactome:R-HSA-5617472|ensembl:ENSP00000367203|dip:DIP-46192N go:"GO:0006310"(DNA recombination)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060717"(chorion development)|go:"GO:1902749"(regulation of cell cycle G2/M phase transition)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR001357(BRCT)|interpro:IPR036420|interpro:IPR037886|mint:Q6ZW49|rcsb pdb:3SQD|reactome:R-HSA-5617472|reactome:R-HSA-5693571|refseq:NP_031375.3|ensembl:ENSG00000157212(gene)|ensembl:ENST00000397192(transcript)|ensembl:ENST00000404141(transcript)|go:"GO:0000416"(positive regulation of histone H3-K36 methylation)|go:"GO:0001570"(vasculogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006281"(DNA repair)|refseq:XP_005249596.1|refseq:XP_016867370.1|dip:DIP-41786N - - comment:"author score: 93" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:sqg+Ikkgvz0uT/gMx1wYs9FaDbI9606 rogid:djzoPtMxXMP9LBvpzVNBcq04QEY9606 rigid:3jKUwGPTqQkRtkasNXUKq3Z6LlA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15550 uniprotkb:Q8NEZ4 intact:EBI-4292203|uniprotkb:Q52LL9|uniprotkb:Q5JVQ7|intact:EBI-28988602|ensembl:ENSP00000367203 intact:EBI-1042997|uniprotkb:Q8NC02|uniprotkb:Q8NDF6|uniprotkb:Q9H9P4|uniprotkb:Q9NR13|uniprotkb:Q9P222|uniprotkb:Q9UDR7|ensembl:ENSP00000262189 psi-mi:kdm6a_human(display_long)|uniprotkb:KDM6A(gene name)|psi-mi:KDM6A(display_short)|uniprotkb:UTX(gene name synonym)|uniprotkb:Histone demethylase UTX(gene name synonym)|uniprotkb:Ubiquitously-transcribed TPR protein on the X chromosome(gene name synonym)|uniprotkb:Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(27) demethylase 6A"(gene name synonym) psi-mi:kmt2c_human(display_long)|uniprotkb:KMT2C(gene name)|psi-mi:KMT2C(display_short)|uniprotkb:HALR(gene name synonym)|uniprotkb:Homologous to ALR protein(gene name synonym)|uniprotkb:KIAA1506(gene name synonym)|uniprotkb:MLL3(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480275|imex:IM-26985-411 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066963.2|ensembl:ENSG00000147050(gene)|ensembl:ENST00000377967(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007507"(heart development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071557"(histone H3-K27 demethylation)|go:"GO:0071558"(histone H3-tri/di-methyl-lysine-27 demethylase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:O15550|rcsb pdb:3AVR|rcsb pdb:3AVS|rcsb pdb:6FUK|rcsb pdb:6FUL|reactome:R-HSA-3214842|reactome:R-HSA-5617472|ensembl:ENSP00000367203|dip:DIP-46192N ensembl:ENSG00000055609(gene)|ensembl:ENST00000262189(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042393"(histone binding)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0097692"(histone H3-K4 monomethylation)|interpro:IPR000637(HMG-I and HMG-Y, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|go:"GO:0005634"(nucleus)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036910|interpro:IPR037877|interpro:IPR041967|interpro:IPR041968|mint:Q8NEZ4|rcsb pdb:2YSM|rcsb pdb:2YUK|rcsb pdb:3UVL|rcsb pdb:4ERY|rcsb pdb:5F59|rcsb pdb:5F6K|rcsb pdb:6KIW|rcsb pdb:6MLC|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8936459|refseq:NP_733751.2|ensembl:ENSP00000262189|ensembl:ENST00000682283|ensembl:ENSP00000507485|dip:DIP-48649N - - comment:"author score: 103" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:sqg+Ikkgvz0uT/gMx1wYs9FaDbI9606 rogid:NZg8HgfbohMT8EEgAdAgWR1AjSo9606 rigid:3jKUwGPTqQkRtkasNXUKq3Z6LlA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15550 uniprotkb:P61964 intact:EBI-4292203|uniprotkb:Q52LL9|uniprotkb:Q5JVQ7|intact:EBI-28988602|ensembl:ENSP00000367203 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 psi-mi:kdm6a_human(display_long)|uniprotkb:KDM6A(gene name)|psi-mi:KDM6A(display_short)|uniprotkb:UTX(gene name synonym)|uniprotkb:Histone demethylase UTX(gene name synonym)|uniprotkb:Ubiquitously-transcribed TPR protein on the X chromosome(gene name synonym)|uniprotkb:Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(27) demethylase 6A"(gene name synonym) psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480275|imex:IM-26985-411 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066963.2|ensembl:ENSG00000147050(gene)|ensembl:ENST00000377967(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007507"(heart development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071557"(histone H3-K27 demethylation)|go:"GO:0071558"(histone H3-tri/di-methyl-lysine-27 demethylase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:O15550|rcsb pdb:3AVR|rcsb pdb:3AVS|rcsb pdb:6FUK|rcsb pdb:6FUL|reactome:R-HSA-3214842|reactome:R-HSA-5617472|ensembl:ENSP00000367203|dip:DIP-46192N refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N - - comment:"author score: 126" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:sqg+Ikkgvz0uT/gMx1wYs9FaDbI9606 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rigid:3jKUwGPTqQkRtkasNXUKq3Z6LlA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15550 uniprotkb:O14686 intact:EBI-4292203|uniprotkb:Q52LL9|uniprotkb:Q5JVQ7|intact:EBI-28988602|ensembl:ENSP00000367203 intact:EBI-996065|uniprotkb:O14687|intact:EBI-28986759|ensembl:ENSP00000301067 psi-mi:kdm6a_human(display_long)|uniprotkb:KDM6A(gene name)|psi-mi:KDM6A(display_short)|uniprotkb:UTX(gene name synonym)|uniprotkb:Histone demethylase UTX(gene name synonym)|uniprotkb:Ubiquitously-transcribed TPR protein on the X chromosome(gene name synonym)|uniprotkb:Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(27) demethylase 6A"(gene name synonym) psi-mi:kmt2d_human(display_long)|uniprotkb:KMT2D(gene name)|psi-mi:KMT2D(display_short)|uniprotkb:ALL1-related protein(gene name synonym)|uniprotkb:ALR(gene name synonym)|uniprotkb:MLL2(gene name synonym)|uniprotkb:MLL4(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480275|imex:IM-26985-411 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066963.2|ensembl:ENSG00000147050(gene)|ensembl:ENST00000377967(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007507"(heart development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071557"(histone H3-K27 demethylation)|go:"GO:0071558"(histone H3-tri/di-methyl-lysine-27 demethylase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:O15550|rcsb pdb:3AVR|rcsb pdb:3AVS|rcsb pdb:6FUK|rcsb pdb:6FUL|reactome:R-HSA-3214842|reactome:R-HSA-5617472|ensembl:ENSP00000367203|dip:DIP-46192N refseq:NP_003473.3|refseq:XP_006719677.1|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0043627"(response to estrogen)|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:1904837"(beta-catenin-TCF complex assembly)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR009071(High mobility group box, HMG)|ensembl:ENSG00000167548(gene)|ensembl:ENST00000301067(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001555"(oocyte growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|interpro:IPR036910|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR037890|interpro:IPR041961|interpro:IPR041964|mint:O14686|rcsb pdb:3UVK|rcsb pdb:4ERQ|rcsb pdb:4Z4P|rcsb pdb:6O7G|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR034732|ensembl:ENSP00000301067|refseq:XP_005269219.1|dip:DIP-37875N - - comment:"author score: 128" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:sqg+Ikkgvz0uT/gMx1wYs9FaDbI9606 rogid:eaCGHR6OqxzL66VYfOrzBWJApHY9606 rigid:3jKUwGPTqQkRtkasNXUKq3Z6LlA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15550 uniprotkb:Q9C005 intact:EBI-4292203|uniprotkb:Q52LL9|uniprotkb:Q5JVQ7|intact:EBI-28988602|ensembl:ENSP00000367203 intact:EBI-744973|uniprotkb:D6W578|ensembl:ENSP00000295066|ensembl:ENSP00000345837 psi-mi:kdm6a_human(display_long)|uniprotkb:KDM6A(gene name)|psi-mi:KDM6A(display_short)|uniprotkb:UTX(gene name synonym)|uniprotkb:Histone demethylase UTX(gene name synonym)|uniprotkb:Ubiquitously-transcribed TPR protein on the X chromosome(gene name synonym)|uniprotkb:Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(27) demethylase 6A"(gene name synonym) psi-mi:dpy30_human(display_long)|uniprotkb:DPY30(gene name)|psi-mi:DPY30(display_short)|uniprotkb:Dpy-30-like protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480275|imex:IM-26985-411 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066963.2|ensembl:ENSG00000147050(gene)|ensembl:ENST00000377967(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007507"(heart development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071557"(histone H3-K27 demethylation)|go:"GO:0071558"(histone H3-tri/di-methyl-lysine-27 demethylase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:O15550|rcsb pdb:3AVR|rcsb pdb:3AVS|rcsb pdb:6FUK|rcsb pdb:6FUL|reactome:R-HSA-3214842|reactome:R-HSA-5617472|ensembl:ENSP00000367203|dip:DIP-46192N refseq:NP_115963.1|ensembl:ENSG00000162961(gene)|ensembl:ENST00000295066(transcript)|ensembl:ENST00000342166(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006348"|go:"GO:0016197"(endosomal transport)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|mint:Q9C005|rcsb pdb:3G36|rcsb pdb:4RIQ|rcsb pdb:4RT4|rcsb pdb:4RTA|rcsb pdb:6E2H|rcsb pdb:6PWV|reactome:R-HSA-3214841|reactome:R-HSA-8936459|refseq:NP_001308138.1|dip:DIP-34476N - - comment:"author score: 141" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:sqg+Ikkgvz0uT/gMx1wYs9FaDbI9606 rogid:yC9NJhTfEIT+YyfWRSJLGbRsQkc9606 rigid:3jKUwGPTqQkRtkasNXUKq3Z6LlA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15550 uniprotkb:Q15291 intact:EBI-4292203|uniprotkb:Q52LL9|uniprotkb:Q5JVQ7|intact:EBI-28988602|ensembl:ENSP00000367203 intact:EBI-592823|uniprotkb:A8K272|uniprotkb:Q7Z6D8|uniprotkb:Q8NDZ7|ensembl:ENSP00000264515 psi-mi:kdm6a_human(display_long)|uniprotkb:KDM6A(gene name)|psi-mi:KDM6A(display_short)|uniprotkb:UTX(gene name synonym)|uniprotkb:Histone demethylase UTX(gene name synonym)|uniprotkb:Ubiquitously-transcribed TPR protein on the X chromosome(gene name synonym)|uniprotkb:Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(27) demethylase 6A"(gene name synonym) psi-mi:rbbp5_human(display_long)|uniprotkb:Retinoblastoma-binding protein RBQ-3(gene name synonym)|uniprotkb:RBBP5(gene name)|psi-mi:RBBP5(display_short)|uniprotkb:RBQ3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480275|imex:IM-26985-411 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066963.2|ensembl:ENSG00000147050(gene)|ensembl:ENST00000377967(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007507"(heart development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071557"(histone H3-K27 demethylation)|go:"GO:0071558"(histone H3-tri/di-methyl-lysine-27 demethylase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:O15550|rcsb pdb:3AVR|rcsb pdb:3AVS|rcsb pdb:6FUK|rcsb pdb:6FUL|reactome:R-HSA-3214842|reactome:R-HSA-5617472|ensembl:ENSP00000367203|dip:DIP-46192N refseq:NP_001180201.1|refseq:NP_001180202.1|refseq:NP_005048.2|dip:DIP-29224N|ensembl:ENSG00000117222(gene)|ensembl:ENST00000264515(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037850|mint:Q15291|rcsb pdb:3P4F|rcsb pdb:4X8N|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6KM7|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6PWX|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664 - - comment:"author score: 152" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:sqg+Ikkgvz0uT/gMx1wYs9FaDbI9606 rogid:Zl8yHcbL1C6StHPyD+875Ccy6gk9606 rigid:3jKUwGPTqQkRtkasNXUKq3Z6LlA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15054 uniprotkb:Q6ZMT4 intact:EBI-2831260|uniprotkb:Q96G33|ensembl:ENSP00000412513|uniprotkb:C9IZ40 intact:EBI-2876984|ensembl:ENSP00000380692|uniprotkb:Q6MZL8|uniprotkb:C9JQU2|uniprotkb:C9JJH9|uniprotkb:Q9C0E5|uniprotkb:A4D1S9 psi-mi:kdm6b_human(display_long)|uniprotkb:KDM6B(gene name)|psi-mi:KDM6B(display_short)|uniprotkb:JMJD3(gene name synonym)|uniprotkb:KIAA0346(gene name synonym)|uniprotkb:JmjC domain-containing protein 3(gene name synonym)|uniprotkb:Jumonji domain-containing protein 3(gene name synonym)|uniprotkb:Lysine demethylase 6B(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(27) demethylase 6B"(gene name synonym) psi-mi:kdm7a_human(display_long)|uniprotkb:KDM7A(gene name)|psi-mi:KDM7A(display_short)|uniprotkb:JHDM1D(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1D(gene name synonym)|uniprotkb:KDM7(gene name synonym)|uniprotkb:KIAA1718(gene name synonym)|uniprotkb:Lysine-specific demethylase 7(gene name synonym)|uniprotkb:[histone H3]-dimethyl-L-lysine9 demethylase 7A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480311|imex:IM-26985-177 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011522052.1|refseq:XP_011522054.1|ensembl:ENSG00000132510(gene)|ensembl:ENST00000448097(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014823"(response to activity)|go:"GO:0021766"(hippocampus development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060992"(response to fungicide)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071557"(histone H3-K27 demethylation)|go:"GO:0071558"(histone H3-tri/di-methyl-lysine-27 demethylase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR029518|mint:O15054|rcsb pdb:2XUE|rcsb pdb:2XXZ|rcsb pdb:4ASK|rcsb pdb:5FP3|rcsb pdb:5OY3|rcsb pdb:6F6D|reactome:R-HSA-2559580|reactome:R-HSA-3214842|refseq:NP_001073893.1|refseq:XP_005256606.1|refseq:XP_005256607.1|refseq:XP_005256608.1|refseq:XP_005256609.1|refseq:XP_006721546.1|refseq:NP_001335645.1|dip:DIP-59912N ensembl:ENSG00000006459(gene)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:0071557"(histone H3-K27 demethylation)|go:"GO:0071558"(histone H3-tri/di-methyl-lysine-27 demethylase activity)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR041070|mint:Q6ZMT4|rcsb pdb:3KV5|rcsb pdb:3KV6|rcsb pdb:3KV9|rcsb pdb:3KVA|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|rcsb pdb:3KVB|ensembl:ENST00000397560(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0030901"(midbrain development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035574"(histone H4-K20 demethylation)|go:"GO:0035575"(histone H4-methyl-lysine-20 demethylase activity)|rcsb pdb:3U78|reactome:R-HSA-3214842|reactome:R-HSA-6802952|refseq:NP_085150.1 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:LWS+OT9hMQ7YuQJJzQqmnF9qBhU9606 rogid:4hG667PsNHVo/iN1r+prkmVYBhQ9606 rigid:QIXoQPmz4fi1jgle6i9tdIi5L2k false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15054 uniprotkb:P35080 intact:EBI-2831260|uniprotkb:Q96G33|ensembl:ENSP00000412513|uniprotkb:C9IZ40 intact:EBI-473138|uniprotkb:Q8WVF9|uniprotkb:Q9HBK2|uniprotkb:B2R4C8|uniprotkb:Q4VBQ4|uniprotkb:D3DNI4|ensembl:ENSP00000239940 psi-mi:kdm6b_human(display_long)|uniprotkb:KDM6B(gene name)|psi-mi:KDM6B(display_short)|uniprotkb:JMJD3(gene name synonym)|uniprotkb:KIAA0346(gene name synonym)|uniprotkb:JmjC domain-containing protein 3(gene name synonym)|uniprotkb:Jumonji domain-containing protein 3(gene name synonym)|uniprotkb:Lysine demethylase 6B(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(27) demethylase 6B"(gene name synonym) psi-mi:prof2_human(display_long)|uniprotkb:PFN2(gene name)|psi-mi:PFN2(display_short)|uniprotkb:Profilin II(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480311|imex:IM-26985-177 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011522052.1|refseq:XP_011522054.1|ensembl:ENSG00000132510(gene)|ensembl:ENST00000448097(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014823"(response to activity)|go:"GO:0021766"(hippocampus development)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045165"(cell fate commitment)|go:"GO:0045446"(endothelial cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060992"(response to fungicide)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071557"(histone H3-K27 demethylation)|go:"GO:0071558"(histone H3-tri/di-methyl-lysine-27 demethylase activity)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR029518|mint:O15054|rcsb pdb:2XUE|rcsb pdb:2XXZ|rcsb pdb:4ASK|rcsb pdb:5FP3|rcsb pdb:5OY3|rcsb pdb:6F6D|reactome:R-HSA-2559580|reactome:R-HSA-3214842|refseq:NP_001073893.1|refseq:XP_005256606.1|refseq:XP_005256607.1|refseq:XP_005256608.1|refseq:XP_005256609.1|refseq:XP_006721546.1|refseq:NP_001335645.1|dip:DIP-59912N refseq:NP_002619.1|refseq:NP_444252.1|ensembl:ENSG00000070087(gene)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010633"(negative regulation of epithelial cell migration)|ensembl:ENST00000239940(transcript)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900028"(negative regulation of ruffle assembly)|interpro:IPR005454(Profilin, Mammalian)|interpro:IPR005455(Profilin, plant)|interpro:IPR027310|interpro:IPR029891|interpro:IPR036140|mint:P35080|rcsb pdb:1D1J|reactome:R-HSA-376176|reactome:R-HSA-5663220 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:LWS+OT9hMQ7YuQJJzQqmnF9qBhU9606 rogid:064T9afVEb7WrgJPLVbKByJDUXc9606 rigid:QIXoQPmz4fi1jgle6i9tdIi5L2k false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41229 uniprotkb:Q01844 intact:EBI-1246541|uniprotkb:B4E3I2|uniprotkb:F5H3T1|ensembl:ENSP00000364550|uniprotkb:Q5JUX3|uniprotkb:Q5JUX4|uniprotkb:Q5JUX5|uniprotkb:Q7Z5S5|uniprotkb:B0QZ44|intact:EBI-28983825 intact:EBI-739737|uniprotkb:Q92635|uniprotkb:Q96FE8|uniprotkb:Q96MX4|uniprotkb:Q9BWA2|uniprotkb:Q5THL0|intact:EBI-28987207|ensembl:ENSP00000381031|intact:EBI-10985407|uniprotkb:B0QYK1|uniprotkb:Q96MN4 psi-mi:kdm5c_human(display_long)|uniprotkb:KDM5C(gene name)|psi-mi:KDM5C(display_short)|uniprotkb:DXS1272E(gene name synonym)|uniprotkb:SMCX(gene name synonym)|uniprotkb:XE169(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1C(gene name synonym)|uniprotkb:Protein SmcX(gene name synonym)|uniprotkb:Protein Xe169(gene name synonym)|uniprotkb:JARID1C(gene name synonym)|uniprotkb:Histone demethylase JARID1C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5C"(gene name synonym) psi-mi:ews_human(display_long)|uniprotkb:EWSR1(gene name)|psi-mi:EWSR1(display_short)|uniprotkb:EWS(gene name synonym)|uniprotkb:EWS oncogene(gene name synonym)|uniprotkb:Ewing sarcoma breakpoint region 1 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480257|imex:IM-26985-99 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140174.1|refseq:NP_004178.2|refseq:NP_001269551.1|ensembl:ENSG00000126012(gene)|ensembl:ENST00000375401(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0051213"(dioxygenase activity)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|refseq:XP_011529128.1|ensembl:ENST00000375379|ensembl:ENSP00000364528|ensembl:ENST00000375383|ensembl:ENSP00000364532|ensembl:ENSP00000364550|ensembl:ENST00000404049|ensembl:ENSP00000385394|ensembl:ENST00000452825|ensembl:ENSP00000445176|refseq:XP_005262092.1|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:P41229|rcsb pdb:2JRZ|rcsb pdb:5FWJ|reactome:R-HSA-3214842|dip:DIP-39663N refseq:NP_001156757.1|refseq:NP_005234.1|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033109|interpro:IPR034869|interpro:IPR034870|interpro:IPR035979|interpro:IPR036443|mint:Q01844|rcsb pdb:2CPE|interpro:IPR001876(Zinc finger, RanBP2-type)|ensembl:ENSG00000182944(gene)|ensembl:ENST00000397938(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_001156759.1|refseq:NP_053733.2|refseq:NP_001156758.1|ensembl:ENST00000332035|ensembl:ENSP00000331699|ensembl:ENST00000333395|ensembl:ENSP00000327456|ensembl:ENSP00000381031|ensembl:ENST00000406548|ensembl:ENSP00000385726|ensembl:ENST00000414183|ensembl:ENSP00000400142|dip:DIP-34449N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:sBtK/VaMcyTMcinoqnOqwBdl7TM9606 rogid:7PxoTjcmcdUA3clzf0eW+iCFaS49606 rigid:sHZV6mixn8Ra8dtnouv1gNbB/68 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41229 uniprotkb:P0CG47 intact:EBI-1246541|uniprotkb:B4E3I2|uniprotkb:F5H3T1|ensembl:ENSP00000364550|uniprotkb:Q5JUX3|uniprotkb:Q5JUX4|uniprotkb:Q5JUX5|uniprotkb:Q7Z5S5|uniprotkb:B0QZ44|intact:EBI-28983825 intact:EBI-413034|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:Q29120|uniprotkb:Q6LBL4|uniprotkb:Q6LDU5|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9BWD6|uniprotkb:Q9BX98|uniprotkb:Q9UEF2|uniprotkb:Q9UEG1|uniprotkb:Q9UEK8|uniprotkb:Q9UPK7|uniprotkb:P62988|ensembl:ENSP00000304697|ensembl:ENSP00000379178|ensembl:ENSP00000379180|ensembl:ENSP00000478771 psi-mi:kdm5c_human(display_long)|uniprotkb:KDM5C(gene name)|psi-mi:KDM5C(display_short)|uniprotkb:DXS1272E(gene name synonym)|uniprotkb:SMCX(gene name synonym)|uniprotkb:XE169(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1C(gene name synonym)|uniprotkb:Protein SmcX(gene name synonym)|uniprotkb:Protein Xe169(gene name synonym)|uniprotkb:JARID1C(gene name synonym)|uniprotkb:Histone demethylase JARID1C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5C"(gene name synonym) psi-mi:ubb_human(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480257|imex:IM-26985-99 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140174.1|refseq:NP_004178.2|refseq:NP_001269551.1|ensembl:ENSG00000126012(gene)|ensembl:ENST00000375401(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0051213"(dioxygenase activity)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|refseq:XP_011529128.1|ensembl:ENST00000375379|ensembl:ENSP00000364528|ensembl:ENST00000375383|ensembl:ENSP00000364532|ensembl:ENSP00000364550|ensembl:ENST00000404049|ensembl:ENSP00000385394|ensembl:ENST00000452825|ensembl:ENSP00000445176|refseq:XP_005262092.1|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:P41229|rcsb pdb:2JRZ|rcsb pdb:5FWJ|reactome:R-HSA-3214842|dip:DIP-39663N refseq:NP_061828.1|refseq:NP_001268645.1|refseq:NP_001268646.1|refseq:NP_001268647.1|refseq:NP_001268648.1|refseq:NP_001268649.1|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG47|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060613"(fat pad development)|rcsb pdb:2KHW|rcsb pdb:2MBB|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:2MRO|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|rcsb pdb:2MSG|go:"GO:1901214"(regulation of neuron death)|rcsb pdb:2N13|rcsb pdb:4UEL|rcsb pdb:4UF6|rcsb pdb:4WHV|rcsb pdb:4WLR|rcsb pdb:4WUR|rcsb pdb:4XOF|rcsb pdb:4ZFR|rcsb pdb:4ZFT|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|rcsb pdb:4ZPZ|rcsb pdb:4ZUX|rcsb pdb:5BNB|rcsb pdb:5CAW|rcsb pdb:5CRA|rcsb pdb:5CVM|rcsb pdb:5CVN|rcsb pdb:5CVO|interpro:IPR000626(Ubiquitin)|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5DFL|rcsb pdb:5DK8|rcsb pdb:5E6J|rcsb pdb:5EDV|rcsb pdb:5EMZ|rcsb pdb:5EYA|rcsb pdb:5GJQ|rcsb pdb:5GO7|rcsb pdb:5GO8|rcsb pdb:5GOB|rcsb pdb:5GOC|rcsb pdb:5GOD|rcsb pdb:5GOG|rcsb pdb:5GOH|rcsb pdb:5GOI|rcsb pdb:5GOJ|rcsb pdb:5GOK|rcsb pdb:5H7S|rcsb pdb:5IBK|rcsb pdb:5IFR|rcsb pdb:5JBY|rcsb pdb:5JG6|rcsb pdb:5JP3|rcsb pdb:5JTJ|rcsb pdb:5JTV|rcsb pdb:5K9P|rcsb pdb:5KGF|rcsb pdb:5KHY|rcsb pdb:5KYC|rcsb pdb:5KYD|rcsb pdb:5KYE|rcsb pdb:5KYF|rcsb pdb:5L8H|rcsb pdb:5L8W|rcsb pdb:5L9T|rcsb pdb:5LN1|rcsb pdb:5LRV|rcsb pdb:5LRW|rcsb pdb:5LRX|rcsb pdb:5M93|rcsb pdb:5MNJ|rcsb pdb:5N2W|rcsb pdb:5N38|rcsb pdb:5NL5|rcsb pdb:5NLJ|rcsb pdb:5NVG|rcsb pdb:5O44|rcsb pdb:5O6T|rcsb pdb:5OHK|rcsb pdb:5OHL|rcsb pdb:5OHN|rcsb pdb:5OHP|rcsb pdb:5TOF|rcsb pdb:5TOG|rcsb pdb:5TUT|rcsb pdb:5TXK|rcsb pdb:5UJL|rcsb pdb:5UJN|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5V1Y|rcsb pdb:5V1Z|rcsb pdb:5VEY|rcsb pdb:5VF0|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5VZM|rcsb pdb:5VZW|rcsb pdb:5W46|rcsb pdb:5WFI|rcsb pdb:5X3M|rcsb pdb:5X3N|rcsb pdb:5X3O|rcsb pdb:5XBO|rcsb pdb:5XDP|rcsb pdb:5XK4|rcsb pdb:5XK5|rcsb pdb:5XPK|rcsb pdb:5YDR|rcsb pdb:5YIJ|rcsb pdb:5YIK|rcsb pdb:5YMY|rcsb pdb:5YT6|rcsb pdb:5ZBU|rcsb pdb:5ZD0|rcsb pdb:6ASR|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6CP2|rcsb pdb:6DGF|rcsb pdb:6EI1|rcsb pdb:6FDK|rcsb pdb:6FGE|rcsb pdb:6FTX|rcsb pdb:6FX4|rcsb pdb:6FYH|rcsb pdb:6GLC|rcsb pdb:6GZS|rcsb pdb:6H4H|rcsb pdb:6HEI|rcsb pdb:6HEK|rcsb pdb:6IF1|rcsb pdb:6ISU|rcsb pdb:6JB6|rcsb pdb:6JB7|rcsb pdb:6JMA|rcsb pdb:6K4I|rcsb pdb:6K9P|rcsb pdb:6KOW|rcsb pdb:6KOX|rcsb pdb:6LP2|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6N13|rcsb pdb:6NJ9|rcsb pdb:6NJG|rcsb pdb:6O96|rcsb pdb:6OAM|rcsb pdb:6PGV|rcsb pdb:6PZV|rcsb pdb:6QF8|rcsb pdb:6QK9|rcsb pdb:6QML|rcsb pdb:6TBM|rcsb pdb:6UH5|rcsb pdb:6XAA|rcsb pdb:7AY2|rcsb pdb:7BBD|rcsb pdb:7CAP|rcsb pdb:7JMS|rcsb pdb:7LYC|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|reactome:R-HSA-1253288|reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-162588|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-168928|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174184|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-211733|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2173788|reactome:R-HSA-2173791|reactome:R-HSA-174178|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2467813|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-349425|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69231|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-983168|reactome:R-HSA-8852276|reactome:R-HSA-8941858|reactome:R-HSA-8854050|reactome:R-HSA-8856825|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-8856828|reactome:R-HSA-8951664|reactome:R-HSA-8863795|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9683683|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-975163|reactome:R-HSA-977225|ensembl:ENSG00000170315(gene)|ensembl:ENST00000302182(transcript)|ensembl:ENST00000395837(transcript)|ensembl:ENST00000395839(transcript)|ensembl:ENST00000614404(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031386"(protein tag)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body) - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:sBtK/VaMcyTMcinoqnOqwBdl7TM9606 rogid:X2Y1hzv2uGZd9FObQD2Qq3SECRo9606 rigid:sHZV6mixn8Ra8dtnouv1gNbB/68 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41229 uniprotkb:Q8NC51 intact:EBI-1246541|uniprotkb:B4E3I2|uniprotkb:F5H3T1|ensembl:ENSP00000364550|uniprotkb:Q5JUX3|uniprotkb:Q5JUX4|uniprotkb:Q5JUX5|uniprotkb:Q7Z5S5|uniprotkb:B0QZ44|intact:EBI-28983825 intact:EBI-523558|uniprotkb:Q8WUH0|uniprotkb:Q96SE2|uniprotkb:Q9BTY3|uniprotkb:Q9BUM4|uniprotkb:Q9Y367|uniprotkb:Q9Y4S3|uniprotkb:Q5VU19|intact:EBI-1058614|ensembl:ENSP00000360034|uniprotkb:Q5VU20|uniprotkb:Q5VU22 psi-mi:kdm5c_human(display_long)|uniprotkb:KDM5C(gene name)|psi-mi:KDM5C(display_short)|uniprotkb:DXS1272E(gene name synonym)|uniprotkb:SMCX(gene name synonym)|uniprotkb:XE169(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1C(gene name synonym)|uniprotkb:Protein SmcX(gene name synonym)|uniprotkb:Protein Xe169(gene name synonym)|uniprotkb:JARID1C(gene name synonym)|uniprotkb:Histone demethylase JARID1C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5C"(gene name synonym) psi-mi:pairb_human(display_long)|uniprotkb:PAI1 RNA-binding protein 1(gene name synonym)|uniprotkb:SERPINE1 mRNA-binding protein 1(gene name synonym)|uniprotkb:CGI-55(orf name)|uniprotkb:SERBP1(gene name)|psi-mi:SERBP1(display_short)|uniprotkb:PAIRBP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480257|imex:IM-26985-99 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140174.1|refseq:NP_004178.2|refseq:NP_001269551.1|ensembl:ENSG00000126012(gene)|ensembl:ENST00000375401(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0051213"(dioxygenase activity)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|refseq:XP_011529128.1|ensembl:ENST00000375379|ensembl:ENSP00000364528|ensembl:ENST00000375383|ensembl:ENSP00000364532|ensembl:ENSP00000364550|ensembl:ENST00000404049|ensembl:ENSP00000385394|ensembl:ENST00000452825|ensembl:ENSP00000445176|refseq:XP_005262092.1|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:P41229|rcsb pdb:2JRZ|rcsb pdb:5FWJ|reactome:R-HSA-3214842|dip:DIP-39663N ensembl:ENSG00000142864(gene)|ensembl:ENST00000370995(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030578"(PML body organization)|go:"GO:0032183"(SUMO binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043022"(ribosome binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006861(Hyaluronan/mRNA binding protein)|interpro:IPR027205|interpro:IPR032381|interpro:IPR039764|mint:Q8NC51|rcsb pdb:4V6X|rcsb pdb:6Z6M|rcsb pdb:6Z6N|refseq:NP_001018077.1|refseq:NP_001018078.1|refseq:NP_001018079.1|refseq:NP_056455.3|dip:DIP-33819N - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:sBtK/VaMcyTMcinoqnOqwBdl7TM9606 rogid:lVkIPRkoXs3B4Qop1pA2zG/RKlo9606 rigid:sHZV6mixn8Ra8dtnouv1gNbB/68 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P41229 uniprotkb:P68363 intact:EBI-1246541|uniprotkb:B4E3I2|uniprotkb:F5H3T1|ensembl:ENSP00000364550|uniprotkb:Q5JUX3|uniprotkb:Q5JUX4|uniprotkb:Q5JUX5|uniprotkb:Q7Z5S5|uniprotkb:B0QZ44|intact:EBI-28983825 intact:EBI-487083|intact:EBI-1384226|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:Q27I68|ensembl:ENSP00000336799|uniprotkb:Q8WU19 psi-mi:kdm5c_human(display_long)|uniprotkb:KDM5C(gene name)|psi-mi:KDM5C(display_short)|uniprotkb:DXS1272E(gene name synonym)|uniprotkb:SMCX(gene name synonym)|uniprotkb:XE169(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1C(gene name synonym)|uniprotkb:Protein SmcX(gene name synonym)|uniprotkb:Protein Xe169(gene name synonym)|uniprotkb:JARID1C(gene name synonym)|uniprotkb:Histone demethylase JARID1C(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5C"(gene name synonym) psi-mi:tba1b_human(display_long)|uniprotkb:TUBA1B(gene name)|psi-mi:TUBA1B(display_short)|uniprotkb:Tubulin alpha-ubiquitous chain(gene name synonym)|uniprotkb:Alpha-tubulin ubiquitous(gene name synonym)|uniprotkb:Tubulin K-alpha-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480257|imex:IM-26985-99 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001140174.1|refseq:NP_004178.2|refseq:NP_001269551.1|ensembl:ENSG00000126012(gene)|ensembl:ENST00000375401(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0051213"(dioxygenase activity)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|refseq:XP_011529128.1|ensembl:ENST00000375379|ensembl:ENSP00000364528|ensembl:ENST00000375383|ensembl:ENSP00000364532|ensembl:ENSP00000364550|ensembl:ENST00000404049|ensembl:ENSP00000385394|ensembl:ENST00000452825|ensembl:ENSP00000445176|refseq:XP_005262092.1|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:P41229|rcsb pdb:2JRZ|rcsb pdb:5FWJ|reactome:R-HSA-3214842|dip:DIP-39663N refseq:NP_006073.2|ensembl:ENSG00000123416(gene)|ensembl:ENST00000336023(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-983189|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|go:"GO:0045121"(membrane raft)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68363|rcsb pdb:2E4H|rcsb pdb:5IJ0|rcsb pdb:5IJ9|rcsb pdb:5N5N|rcsb pdb:6E7B|rcsb pdb:6E7C|rcsb pdb:6I2I|go:"GO:0051301"(cell division)|rcsb pdb:6J4V|rcsb pdb:6J8O|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|rcsb pdb:6S8L|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9013407|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-2132295|reactome:R-HSA-9668328 - - comment:"author score: 28" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:sBtK/VaMcyTMcinoqnOqwBdl7TM9606 rogid:D4YpuLCXl/S+53qV7P7sF81aARY9606 rigid:sHZV6mixn8Ra8dtnouv1gNbB/68 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UGL1 uniprotkb:Q9Y3Y2 intact:EBI-2514978|uniprotkb:Q9Y3Q5|uniprotkb:O95811|uniprotkb:Q15752|ensembl:ENSP00000356234 intact:EBI-347794|uniprotkb:Q2VPI9|uniprotkb:Q5T7Y8|uniprotkb:Q5T7Z0|uniprotkb:Q6NSM4|uniprotkb:Q6PB28|uniprotkb:Q8WYT9|uniprotkb:Q9BUC5|uniprotkb:Q9H034|uniprotkb:Q9H2L0|uniprotkb:Q0VAQ8|uniprotkb:D3DV55|uniprotkb:Q5T7Y9|ensembl:ENSP00000357683 psi-mi:kdm5b_human(display_long)|uniprotkb:KDM5B(gene name)|psi-mi:KDM5B(display_short)|uniprotkb:JARID1B(gene name synonym)|uniprotkb:PLU1(gene name synonym)|uniprotkb:RBBP2H1(gene name synonym)|uniprotkb:Histone demethylase JARID1B(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1B(gene name synonym)|uniprotkb:PLU-1(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2 homolog 1(gene name synonym)|uniprotkb:Cancer/testis antigen 31(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5B"(gene name synonym) psi-mi:chtop_human(display_long)|uniprotkb:HT031(orf name)|uniprotkb:PP7704(orf name)|uniprotkb:FOP(gene name synonym)|uniprotkb:CHTOP(gene name)|psi-mi:CHTOP(display_short)|uniprotkb:C1orf77(gene name synonym)|uniprotkb:Friend of PRMT1 protein(gene name synonym)|uniprotkb:Small arginine- and glycine-rich protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480242|imex:IM-26985-333 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001300971.1|refseq:NP_006609.3|dip:DIP-53652N|ensembl:ENSG00000117139(gene)|ensembl:ENST00000367265(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007338"(single fertilization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042393"(histone binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060763"(mammary duct terminal end bud growth)|go:"GO:0060992"(response to fungicide)|go:"GO:0061038"(uterus morphogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000864"(regulation of estradiol secretion)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:Q9UGL1|rcsb pdb:2MA5|rcsb pdb:2MNY|rcsb pdb:2MNZ|rcsb pdb:5A1F|rcsb pdb:5A3N|rcsb pdb:5A3P|rcsb pdb:5A3T|rcsb pdb:5A3W|rcsb pdb:5FPL|rcsb pdb:5FPU|rcsb pdb:5FUN|rcsb pdb:5FUP|rcsb pdb:5FV3|rcsb pdb:5FY4|rcsb pdb:5FY5|rcsb pdb:5FY9|rcsb pdb:5FYB|rcsb pdb:5FYS|rcsb pdb:5FYT|rcsb pdb:5FYU|rcsb pdb:5FYV|rcsb pdb:5FYY|rcsb pdb:5FYZ|rcsb pdb:5FZ0|rcsb pdb:5FZ1|rcsb pdb:5FZ3|rcsb pdb:5FZ4|rcsb pdb:5FZ6|rcsb pdb:5FZ7|rcsb pdb:5FZ8|rcsb pdb:5FZ9|rcsb pdb:5FZA|rcsb pdb:5FZB|rcsb pdb:5FZC|rcsb pdb:5FZD|rcsb pdb:5FZE|rcsb pdb:5FZF|rcsb pdb:5FZG|rcsb pdb:5FZH|rcsb pdb:5FZI|rcsb pdb:5FZK|rcsb pdb:5FZL|rcsb pdb:5FZM|go:"GO:0070306"(lens fiber cell differentiation)|rcsb pdb:5LW9|rcsb pdb:5LWB|rcsb pdb:6EIN|rcsb pdb:6EIU|rcsb pdb:6EIY|rcsb pdb:6EJ0|rcsb pdb:6EJ1|rcsb pdb:6EK6|rcsb pdb:6H4Z|rcsb pdb:6H50|rcsb pdb:6H51|rcsb pdb:6H52|rcsb pdb:6RBI|reactome:R-HSA-3214842|reactome:R-HSA-8866911 refseq:NP_001304006.1|refseq:NP_001193541.1|refseq:NP_056422.2|refseq:NP_001231593.1|ensembl:ENSG00000160679(gene)|ensembl:ENST00000368694(transcript)|go:"GO:0000346"(transcription export complex)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0051096"(positive regulation of helicase activity)|interpro:IPR025715|mint:Q9Y3Y2|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:HXNXUmikf5+ywMuA4UStrabarzM9606 rogid:mNq0QTGQnGABQwIL2S90Hbp3Nm89606 rigid:r4MdUrkIrUOcXhRsNT6tmueUKQ4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UGL1 uniprotkb:O94903 intact:EBI-2514978|uniprotkb:Q9Y3Q5|uniprotkb:O95811|uniprotkb:Q15752|ensembl:ENSP00000356234 intact:EBI-2860631|uniprotkb:Q6FI94|ensembl:ENSP00000333551 psi-mi:kdm5b_human(display_long)|uniprotkb:KDM5B(gene name)|psi-mi:KDM5B(display_short)|uniprotkb:JARID1B(gene name synonym)|uniprotkb:PLU1(gene name synonym)|uniprotkb:RBBP2H1(gene name synonym)|uniprotkb:Histone demethylase JARID1B(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1B(gene name synonym)|uniprotkb:PLU-1(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2 homolog 1(gene name synonym)|uniprotkb:Cancer/testis antigen 31(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5B"(gene name synonym) psi-mi:plphp_human(display_long)|uniprotkb:PLPBP(gene name)|psi-mi:PLPBP(display_short)|uniprotkb:PROSC(gene name synonym)|uniprotkb:Proline synthase co-transcribed bacterial homolog protein(gene name synonym)|uniprotkb:Pyridoxal phosphate-binding protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480242|imex:IM-26985-333 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001300971.1|refseq:NP_006609.3|dip:DIP-53652N|ensembl:ENSG00000117139(gene)|ensembl:ENST00000367265(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007338"(single fertilization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042393"(histone binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060763"(mammary duct terminal end bud growth)|go:"GO:0060992"(response to fungicide)|go:"GO:0061038"(uterus morphogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000864"(regulation of estradiol secretion)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:Q9UGL1|rcsb pdb:2MA5|rcsb pdb:2MNY|rcsb pdb:2MNZ|rcsb pdb:5A1F|rcsb pdb:5A3N|rcsb pdb:5A3P|rcsb pdb:5A3T|rcsb pdb:5A3W|rcsb pdb:5FPL|rcsb pdb:5FPU|rcsb pdb:5FUN|rcsb pdb:5FUP|rcsb pdb:5FV3|rcsb pdb:5FY4|rcsb pdb:5FY5|rcsb pdb:5FY9|rcsb pdb:5FYB|rcsb pdb:5FYS|rcsb pdb:5FYT|rcsb pdb:5FYU|rcsb pdb:5FYV|rcsb pdb:5FYY|rcsb pdb:5FYZ|rcsb pdb:5FZ0|rcsb pdb:5FZ1|rcsb pdb:5FZ3|rcsb pdb:5FZ4|rcsb pdb:5FZ6|rcsb pdb:5FZ7|rcsb pdb:5FZ8|rcsb pdb:5FZ9|rcsb pdb:5FZA|rcsb pdb:5FZB|rcsb pdb:5FZC|rcsb pdb:5FZD|rcsb pdb:5FZE|rcsb pdb:5FZF|rcsb pdb:5FZG|rcsb pdb:5FZH|rcsb pdb:5FZI|rcsb pdb:5FZK|rcsb pdb:5FZL|rcsb pdb:5FZM|go:"GO:0070306"(lens fiber cell differentiation)|rcsb pdb:5LW9|rcsb pdb:5LWB|rcsb pdb:6EIN|rcsb pdb:6EIU|rcsb pdb:6EIY|rcsb pdb:6EJ0|rcsb pdb:6EJ1|rcsb pdb:6EK6|rcsb pdb:6H4Z|rcsb pdb:6H50|rcsb pdb:6H51|rcsb pdb:6H52|rcsb pdb:6RBI|reactome:R-HSA-3214842|reactome:R-HSA-8866911 refseq:NP_009129.1|ensembl:ENSG00000147471(gene)|ensembl:ENST00000328195(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030170"(pyridoxal phosphate binding)|interpro:IPR001608(Alanine racemase, N-terminal)|interpro:IPR011078(Predicted pyridoxal phosphate-dependent enzyme, YBL036C type)|interpro:IPR029066|mint:O94903 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:HXNXUmikf5+ywMuA4UStrabarzM9606 rogid:xrOEPMjG0y+otG21Al6Q0UuQcEY9606 rigid:r4MdUrkIrUOcXhRsNT6tmueUKQ4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UGL1 uniprotkb:Q8IY37 intact:EBI-2514978|uniprotkb:Q9Y3Q5|uniprotkb:O95811|uniprotkb:Q15752|ensembl:ENSP00000356234 intact:EBI-308285|uniprotkb:Q9BUI7|uniprotkb:Q9P211|ensembl:ENSP00000311135 psi-mi:kdm5b_human(display_long)|uniprotkb:KDM5B(gene name)|psi-mi:KDM5B(display_short)|uniprotkb:JARID1B(gene name synonym)|uniprotkb:PLU1(gene name synonym)|uniprotkb:RBBP2H1(gene name synonym)|uniprotkb:Histone demethylase JARID1B(gene name synonym)|uniprotkb:Jumonji/ARID domain-containing protein 1B(gene name synonym)|uniprotkb:PLU-1(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2 homolog 1(gene name synonym)|uniprotkb:Cancer/testis antigen 31(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5B"(gene name synonym) psi-mi:dhx37_human(display_long)|uniprotkb:DHX37(gene name)|psi-mi:DHX37(display_short)|uniprotkb:DDX37(gene name synonym)|uniprotkb:KIAA1517(gene name synonym)|uniprotkb:DEAH box protein 37(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480242|imex:IM-26985-333 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001300971.1|refseq:NP_006609.3|dip:DIP-53652N|ensembl:ENSG00000117139(gene)|ensembl:ENST00000367265(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007338"(single fertilization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0042393"(histone binding)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060763"(mammary duct terminal end bud growth)|go:"GO:0060992"(response to fungicide)|go:"GO:0061038"(uterus morphogenesis)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000864"(regulation of estradiol secretion)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:Q9UGL1|rcsb pdb:2MA5|rcsb pdb:2MNY|rcsb pdb:2MNZ|rcsb pdb:5A1F|rcsb pdb:5A3N|rcsb pdb:5A3P|rcsb pdb:5A3T|rcsb pdb:5A3W|rcsb pdb:5FPL|rcsb pdb:5FPU|rcsb pdb:5FUN|rcsb pdb:5FUP|rcsb pdb:5FV3|rcsb pdb:5FY4|rcsb pdb:5FY5|rcsb pdb:5FY9|rcsb pdb:5FYB|rcsb pdb:5FYS|rcsb pdb:5FYT|rcsb pdb:5FYU|rcsb pdb:5FYV|rcsb pdb:5FYY|rcsb pdb:5FYZ|rcsb pdb:5FZ0|rcsb pdb:5FZ1|rcsb pdb:5FZ3|rcsb pdb:5FZ4|rcsb pdb:5FZ6|rcsb pdb:5FZ7|rcsb pdb:5FZ8|rcsb pdb:5FZ9|rcsb pdb:5FZA|rcsb pdb:5FZB|rcsb pdb:5FZC|rcsb pdb:5FZD|rcsb pdb:5FZE|rcsb pdb:5FZF|rcsb pdb:5FZG|rcsb pdb:5FZH|rcsb pdb:5FZI|rcsb pdb:5FZK|rcsb pdb:5FZL|rcsb pdb:5FZM|go:"GO:0070306"(lens fiber cell differentiation)|rcsb pdb:5LW9|rcsb pdb:5LWB|rcsb pdb:6EIN|rcsb pdb:6EIU|rcsb pdb:6EIY|rcsb pdb:6EJ0|rcsb pdb:6EJ1|rcsb pdb:6EK6|rcsb pdb:6H4Z|rcsb pdb:6H50|rcsb pdb:6H51|rcsb pdb:6H52|rcsb pdb:6RBI|reactome:R-HSA-3214842|reactome:R-HSA-8866911 refseq:NP_116045.2|ensembl:ENSG00000150990(gene)|ensembl:ENST00000308736(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007420"(brain development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042255"(ribosome assembly)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000020"(positive regulation of male gonad development)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|mint:Q8IY37|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:HXNXUmikf5+ywMuA4UStrabarzM9606 rogid:y+2TFmurlGgCJ2pjTjfAttqC3xE9606 rigid:r4MdUrkIrUOcXhRsNT6tmueUKQ4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P29375 uniprotkb:Q92769 intact:EBI-1560836|uniprotkb:Q86XZ1|uniprotkb:A8MV76|uniprotkb:Q4LE72|ensembl:ENSP00000382688 intact:EBI-301821|uniprotkb:Q5SRI8|uniprotkb:Q5SZ86|uniprotkb:Q8NEH4|uniprotkb:B4DL58|ensembl:ENSP00000430432|uniprotkb:E1P561|uniprotkb:B3KRS5 psi-mi:kdm5a_human(display_long)|uniprotkb:Jumonji/ARID domain-containing protein 1A(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2(gene name synonym)|uniprotkb:KDM5A(gene name)|psi-mi:KDM5A(display_short)|uniprotkb:RBBP2(gene name synonym)|uniprotkb:RBP2(gene name synonym)|uniprotkb:JARID1A(gene name synonym)|uniprotkb:Histone demethylase JARID1A(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5A"(gene name synonym) psi-mi:hdac2_human(display_long)|uniprotkb:HDAC2(gene name)|psi-mi:HDAC2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480200|imex:IM-26985-409 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036068.1|dip:DIP-472N|ensembl:ENSG00000073614(gene)|ensembl:ENST00000399788(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051213"(dioxygenase activity)|go:"GO:1901726"(negative regulation of histone deacetylase activity)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:P29375|rcsb pdb:2JXJ|rcsb pdb:2KGG|rcsb pdb:2KGI|rcsb pdb:3GL6|rcsb pdb:5C11|rcsb pdb:5CEH|rcsb pdb:5E6H|rcsb pdb:5ISL|rcsb pdb:5IVB|rcsb pdb:5IVC|rcsb pdb:5IVE|rcsb pdb:5IVF|rcsb pdb:5IVJ|rcsb pdb:5IVV|rcsb pdb:5IVY|rcsb pdb:5IW0|rcsb pdb:5IWF|rcsb pdb:5K4L|rcsb pdb:5V9P|rcsb pdb:5V9T|rcsb pdb:6BGU|rcsb pdb:6BGV|rcsb pdb:6BGW|rcsb pdb:6BGX|rcsb pdb:6BGY|rcsb pdb:6BGZ|rcsb pdb:6BH0|rcsb pdb:6BH1|rcsb pdb:6BH2|rcsb pdb:6BH3|rcsb pdb:6BH4|rcsb pdb:6BH5|rcsb pdb:6DQ4|rcsb pdb:6DQ5|rcsb pdb:6DQ6|rcsb pdb:6DQ7|rcsb pdb:6DQ8|rcsb pdb:6DQ9|rcsb pdb:6DQA|rcsb pdb:6DQB|rcsb pdb:6DQC|rcsb pdb:6DQD|rcsb pdb:6DQE|rcsb pdb:6DQF|rcsb pdb:7KLO|rcsb pdb:7KLR|reactome:R-HSA-3214842 go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035094"(response to nicotine)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042220"(response to cocaine)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q92769|rcsb pdb:3MAX|rcsb pdb:4LXZ|rcsb pdb:4LY1|rcsb pdb:5IWG|rcsb pdb:5IX0|rcsb pdb:6G3O|rcsb pdb:6WBW|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|ensembl:ENSG00000196591(gene)|ensembl:ENST00000519065(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|rcsb pdb:6WHN|rcsb pdb:6WHO|rcsb pdb:6WHQ|rcsb pdb:6WHZ|rcsb pdb:6WI3|rcsb pdb:6XDM|rcsb pdb:6XEB|rcsb pdb:6XEC|rcsb pdb:7KBG|rcsb pdb:7KBH|rcsb pdb:7LTG|rcsb pdb:7LTK|rcsb pdb:7LTL|reactome:R-HSA-193670|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9615017|reactome:R-HSA-9619665|reactome:R-HSA-9679191|reactome:R-HSA-983231|rcsb pdb:6WBZ|refseq:NP_001518.3|dip:DIP-24220N|refseq:XP_011534090.1|refseq:XP_016866288.1 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:F6XYSW2/X7BvtDjU/1wBBa8jhTM9606 rogid:K4PpGz9E9/TrQZsgvrJuc+uYCn89606 rigid:CMVUj+/XkV1BcKwGN7UTNMxXN30 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P29375 uniprotkb:Q99417 intact:EBI-1560836|uniprotkb:Q86XZ1|uniprotkb:A8MV76|uniprotkb:Q4LE72|ensembl:ENSP00000382688 intact:EBI-716185|intact:EBI-2559925|uniprotkb:Q5TA64|uniprotkb:Q96HE2|uniprotkb:B2R4N0|ensembl:ENSP00000380702 psi-mi:kdm5a_human(display_long)|uniprotkb:Jumonji/ARID domain-containing protein 1A(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2(gene name synonym)|uniprotkb:KDM5A(gene name)|psi-mi:KDM5A(display_short)|uniprotkb:RBBP2(gene name synonym)|uniprotkb:RBP2(gene name synonym)|uniprotkb:JARID1A(gene name synonym)|uniprotkb:Histone demethylase JARID1A(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5A"(gene name synonym) psi-mi:mycbp_human(display_long)|uniprotkb:Associate of Myc 1(gene name synonym)|uniprotkb:MYCBP(gene name)|psi-mi:MYCBP(display_short)|uniprotkb:AMY1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480200|imex:IM-26985-409 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036068.1|dip:DIP-472N|ensembl:ENSG00000073614(gene)|ensembl:ENST00000399788(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051213"(dioxygenase activity)|go:"GO:1901726"(negative regulation of histone deacetylase activity)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:P29375|rcsb pdb:2JXJ|rcsb pdb:2KGG|rcsb pdb:2KGI|rcsb pdb:3GL6|rcsb pdb:5C11|rcsb pdb:5CEH|rcsb pdb:5E6H|rcsb pdb:5ISL|rcsb pdb:5IVB|rcsb pdb:5IVC|rcsb pdb:5IVE|rcsb pdb:5IVF|rcsb pdb:5IVJ|rcsb pdb:5IVV|rcsb pdb:5IVY|rcsb pdb:5IW0|rcsb pdb:5IWF|rcsb pdb:5K4L|rcsb pdb:5V9P|rcsb pdb:5V9T|rcsb pdb:6BGU|rcsb pdb:6BGV|rcsb pdb:6BGW|rcsb pdb:6BGX|rcsb pdb:6BGY|rcsb pdb:6BGZ|rcsb pdb:6BH0|rcsb pdb:6BH1|rcsb pdb:6BH2|rcsb pdb:6BH3|rcsb pdb:6BH4|rcsb pdb:6BH5|rcsb pdb:6DQ4|rcsb pdb:6DQ5|rcsb pdb:6DQ6|rcsb pdb:6DQ7|rcsb pdb:6DQ8|rcsb pdb:6DQ9|rcsb pdb:6DQA|rcsb pdb:6DQB|rcsb pdb:6DQC|rcsb pdb:6DQD|rcsb pdb:6DQE|rcsb pdb:6DQF|rcsb pdb:7KLO|rcsb pdb:7KLR|reactome:R-HSA-3214842 refseq:NP_036465.2|ensembl:ENSG00000214114(gene)|ensembl:ENST00000397572(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007283"(spermatogenesis)|interpro:IPR026060|mint:Q99417|rcsb pdb:2YY0 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:F6XYSW2/X7BvtDjU/1wBBa8jhTM9606 rogid:jIStn1A10DDkgTuwVeKpDPJ6tIs9606 rigid:CMVUj+/XkV1BcKwGN7UTNMxXN30 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P29375 uniprotkb:Q9ULU4 intact:EBI-1560836|uniprotkb:Q86XZ1|uniprotkb:A8MV76|uniprotkb:Q4LE72|ensembl:ENSP00000382688 intact:EBI-765834|uniprotkb:Q13517|uniprotkb:Q4JJ94|uniprotkb:Q4JJ95|uniprotkb:Q5TH09|uniprotkb:Q6MZM1|uniprotkb:Q8WXC5|uniprotkb:Q9H1F3|uniprotkb:Q9H1F4|uniprotkb:Q9H1F5|uniprotkb:Q9H1L8|uniprotkb:Q9H1L9|uniprotkb:Q9H2G5|uniprotkb:Q9NYN3|uniprotkb:Q9UIX6|uniprotkb:Q2HXV7|uniprotkb:E1P5U5|uniprotkb:B7Z680|uniprotkb:Q2HXV2|uniprotkb:Q2HXV8|uniprotkb:Q2HXW0|uniprotkb:Q2HXW1|uniprotkb:Q2HXW2|uniprotkb:Q2HXV4|uniprotkb:Q2HXV9|uniprotkb:B3KVL2|uniprotkb:B7Z2A8|uniprotkb:B7Z3E0|uniprotkb:B7ZM62|uniprotkb:F5H0X3|uniprotkb:H7C0U2|uniprotkb:J3KPU3|uniprotkb:Q2HXV1|uniprotkb:Q2HXV3|uniprotkb:Q5TH11|ensembl:ENSP00000312237 psi-mi:kdm5a_human(display_long)|uniprotkb:Jumonji/ARID domain-containing protein 1A(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2(gene name synonym)|uniprotkb:KDM5A(gene name)|psi-mi:KDM5A(display_short)|uniprotkb:RBBP2(gene name synonym)|uniprotkb:RBP2(gene name synonym)|uniprotkb:JARID1A(gene name synonym)|uniprotkb:Histone demethylase JARID1A(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5A"(gene name synonym) psi-mi:pkcb1_human(display_long)|uniprotkb:Rack7(gene name synonym)|uniprotkb:Cutaneous T-cell lymphoma-associated antigen se14-3(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 8(gene name synonym)|uniprotkb:ZMYND8(gene name)|psi-mi:ZMYND8(display_short)|uniprotkb:KIAA1125(gene name synonym)|uniprotkb:RACK7(gene name synonym)|uniprotkb:PRKCBP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480200|imex:IM-26985-409 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036068.1|dip:DIP-472N|ensembl:ENSG00000073614(gene)|ensembl:ENST00000399788(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051213"(dioxygenase activity)|go:"GO:1901726"(negative regulation of histone deacetylase activity)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:P29375|rcsb pdb:2JXJ|rcsb pdb:2KGG|rcsb pdb:2KGI|rcsb pdb:3GL6|rcsb pdb:5C11|rcsb pdb:5CEH|rcsb pdb:5E6H|rcsb pdb:5ISL|rcsb pdb:5IVB|rcsb pdb:5IVC|rcsb pdb:5IVE|rcsb pdb:5IVF|rcsb pdb:5IVJ|rcsb pdb:5IVV|rcsb pdb:5IVY|rcsb pdb:5IW0|rcsb pdb:5IWF|rcsb pdb:5K4L|rcsb pdb:5V9P|rcsb pdb:5V9T|rcsb pdb:6BGU|rcsb pdb:6BGV|rcsb pdb:6BGW|rcsb pdb:6BGX|rcsb pdb:6BGY|rcsb pdb:6BGZ|rcsb pdb:6BH0|rcsb pdb:6BH1|rcsb pdb:6BH2|rcsb pdb:6BH3|rcsb pdb:6BH4|rcsb pdb:6BH5|rcsb pdb:6DQ4|rcsb pdb:6DQ5|rcsb pdb:6DQ6|rcsb pdb:6DQ7|rcsb pdb:6DQ8|rcsb pdb:6DQ9|rcsb pdb:6DQA|rcsb pdb:6DQB|rcsb pdb:6DQC|rcsb pdb:6DQD|rcsb pdb:6DQE|rcsb pdb:6DQF|rcsb pdb:7KLO|rcsb pdb:7KLR|reactome:R-HSA-3214842 refseq:NP_036540.3|refseq:NP_898868.1|refseq:NP_898869.1|refseq:XP_011527053.1|refseq:NP_001268711.1|refseq:NP_001268706.1|refseq:NP_001268710.1|ensembl:ENST00000262975|ensembl:ENSP00000262975|ensembl:ENSP00000312237|ensembl:ENST00000352431|ensembl:ENSP00000335537|ensembl:ENST00000355972|ensembl:ENSP00000348246|ensembl:ENST00000360911|ensembl:ENSP00000354166|ensembl:ENST00000372023|ensembl:ENSP00000361093|ensembl:ENST00000396281|ensembl:ENSP00000379577|refseq:NP_001268702.1|refseq:NP_001268703.1|refseq:NP_001268704.1|refseq:NP_001268705.1|refseq:NP_001268707.1|refseq:NP_001268712.1|refseq:XP_005260417.1|refseq:XP_005260423.1|ensembl:ENST00000446994|ensembl:ENSP00000396725|ensembl:ENST00000458360|ensembl:ENSP00000392964|ensembl:ENST00000461685|ensembl:ENSP00000418210|ensembl:ENST00000471951|ensembl:ENSP00000420095|ensembl:ENST00000536340|ensembl:ENSP00000439800|ensembl:ENST00000540497|ensembl:ENSP00000443086|refseq:NP_001268713.1|refseq:XP_005260413.1|refseq:NP_001268700.1|refseq:NP_001268701.1|refseq:XP_006723825.1|refseq:XP_016883250.1|refseq:XP_016883256.1|refseq:XP_016883257.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902897"(regulation of postsynaptic density protein 95 clustering)|go:"GO:1902952"(positive regulation of dendritic spine maintenance)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR021931|interpro:IPR035505|interpro:IPR036427|interpro:IPR037967|interpro:IPR044075|mint:Q9ULU4|rcsb pdb:4COS|rcsb pdb:5B73|rcsb pdb:5MQ4|go:"GO:0005654"(nucleoplasm)|rcsb pdb:5Y1Z|ensembl:ENSG00000101040(gene)|ensembl:ENST00000311275(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus) - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:F6XYSW2/X7BvtDjU/1wBBa8jhTM9606 rogid:z46jFcDnmKauE75GMeApPZmfdDM9606 rigid:CMVUj+/XkV1BcKwGN7UTNMxXN30 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P29375 uniprotkb:P68363 intact:EBI-1560836|uniprotkb:Q86XZ1|uniprotkb:A8MV76|uniprotkb:Q4LE72|ensembl:ENSP00000382688 intact:EBI-487083|intact:EBI-1384226|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:Q27I68|ensembl:ENSP00000336799|uniprotkb:Q8WU19 psi-mi:kdm5a_human(display_long)|uniprotkb:Jumonji/ARID domain-containing protein 1A(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2(gene name synonym)|uniprotkb:KDM5A(gene name)|psi-mi:KDM5A(display_short)|uniprotkb:RBBP2(gene name synonym)|uniprotkb:RBP2(gene name synonym)|uniprotkb:JARID1A(gene name synonym)|uniprotkb:Histone demethylase JARID1A(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5A"(gene name synonym) psi-mi:tba1b_human(display_long)|uniprotkb:TUBA1B(gene name)|psi-mi:TUBA1B(display_short)|uniprotkb:Tubulin alpha-ubiquitous chain(gene name synonym)|uniprotkb:Alpha-tubulin ubiquitous(gene name synonym)|uniprotkb:Tubulin K-alpha-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480200|imex:IM-26985-409 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036068.1|dip:DIP-472N|ensembl:ENSG00000073614(gene)|ensembl:ENST00000399788(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051213"(dioxygenase activity)|go:"GO:1901726"(negative regulation of histone deacetylase activity)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:P29375|rcsb pdb:2JXJ|rcsb pdb:2KGG|rcsb pdb:2KGI|rcsb pdb:3GL6|rcsb pdb:5C11|rcsb pdb:5CEH|rcsb pdb:5E6H|rcsb pdb:5ISL|rcsb pdb:5IVB|rcsb pdb:5IVC|rcsb pdb:5IVE|rcsb pdb:5IVF|rcsb pdb:5IVJ|rcsb pdb:5IVV|rcsb pdb:5IVY|rcsb pdb:5IW0|rcsb pdb:5IWF|rcsb pdb:5K4L|rcsb pdb:5V9P|rcsb pdb:5V9T|rcsb pdb:6BGU|rcsb pdb:6BGV|rcsb pdb:6BGW|rcsb pdb:6BGX|rcsb pdb:6BGY|rcsb pdb:6BGZ|rcsb pdb:6BH0|rcsb pdb:6BH1|rcsb pdb:6BH2|rcsb pdb:6BH3|rcsb pdb:6BH4|rcsb pdb:6BH5|rcsb pdb:6DQ4|rcsb pdb:6DQ5|rcsb pdb:6DQ6|rcsb pdb:6DQ7|rcsb pdb:6DQ8|rcsb pdb:6DQ9|rcsb pdb:6DQA|rcsb pdb:6DQB|rcsb pdb:6DQC|rcsb pdb:6DQD|rcsb pdb:6DQE|rcsb pdb:6DQF|rcsb pdb:7KLO|rcsb pdb:7KLR|reactome:R-HSA-3214842 refseq:NP_006073.2|ensembl:ENSG00000123416(gene)|ensembl:ENST00000336023(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-983189|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|go:"GO:0045121"(membrane raft)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68363|rcsb pdb:2E4H|rcsb pdb:5IJ0|rcsb pdb:5IJ9|rcsb pdb:5N5N|rcsb pdb:6E7B|rcsb pdb:6E7C|rcsb pdb:6I2I|go:"GO:0051301"(cell division)|rcsb pdb:6J4V|rcsb pdb:6J8O|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|rcsb pdb:6S8L|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9013407|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-2132295|reactome:R-HSA-9668328 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:F6XYSW2/X7BvtDjU/1wBBa8jhTM9606 rogid:D4YpuLCXl/S+53qV7P7sF81aARY9606 rigid:CMVUj+/XkV1BcKwGN7UTNMxXN30 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P29375 uniprotkb:Q9Y6H1 intact:EBI-1560836|uniprotkb:Q86XZ1|uniprotkb:A8MV76|uniprotkb:Q4LE72|ensembl:ENSP00000382688 intact:EBI-2321769|uniprotkb:Q498C3|uniprotkb:Q6NZ50|ensembl:ENSP00000378812 psi-mi:kdm5a_human(display_long)|uniprotkb:Jumonji/ARID domain-containing protein 1A(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2(gene name synonym)|uniprotkb:KDM5A(gene name)|psi-mi:KDM5A(display_short)|uniprotkb:RBBP2(gene name synonym)|uniprotkb:RBP2(gene name synonym)|uniprotkb:JARID1A(gene name synonym)|uniprotkb:Histone demethylase JARID1A(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5A"(gene name synonym) psi-mi:chch2_human(display_long)|uniprotkb:CHCHD2(gene name)|psi-mi:CHCHD2(display_short)|uniprotkb:C7orf17(gene name synonym)|uniprotkb:HCV NS2 trans-regulated protein(gene name synonym)|uniprotkb:Aging-associated gene 10 protein(gene name synonym)|uniprotkb:AAG10(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480200|imex:IM-26985-409 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036068.1|dip:DIP-472N|ensembl:ENSG00000073614(gene)|ensembl:ENST00000399788(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051213"(dioxygenase activity)|go:"GO:1901726"(negative regulation of histone deacetylase activity)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:P29375|rcsb pdb:2JXJ|rcsb pdb:2KGG|rcsb pdb:2KGI|rcsb pdb:3GL6|rcsb pdb:5C11|rcsb pdb:5CEH|rcsb pdb:5E6H|rcsb pdb:5ISL|rcsb pdb:5IVB|rcsb pdb:5IVC|rcsb pdb:5IVE|rcsb pdb:5IVF|rcsb pdb:5IVJ|rcsb pdb:5IVV|rcsb pdb:5IVY|rcsb pdb:5IW0|rcsb pdb:5IWF|rcsb pdb:5K4L|rcsb pdb:5V9P|rcsb pdb:5V9T|rcsb pdb:6BGU|rcsb pdb:6BGV|rcsb pdb:6BGW|rcsb pdb:6BGX|rcsb pdb:6BGY|rcsb pdb:6BGZ|rcsb pdb:6BH0|rcsb pdb:6BH1|rcsb pdb:6BH2|rcsb pdb:6BH3|rcsb pdb:6BH4|rcsb pdb:6BH5|rcsb pdb:6DQ4|rcsb pdb:6DQ5|rcsb pdb:6DQ6|rcsb pdb:6DQ7|rcsb pdb:6DQ8|rcsb pdb:6DQ9|rcsb pdb:6DQA|rcsb pdb:6DQB|rcsb pdb:6DQC|rcsb pdb:6DQD|rcsb pdb:6DQE|rcsb pdb:6DQF|rcsb pdb:7KLO|rcsb pdb:7KLR|reactome:R-HSA-3214842 refseq:NP_057223.1|ensembl:ENSG00000106153(gene)|ensembl:ENST00000395422(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900037"(regulation of cellular response to hypoxia)|go:"GO:1905448"(positive regulation of mitochondrial ATP synthesis coupled electron transport)|interpro:IPR010625(CHCH)|mint:Q9Y6H1|reactome:R-HSA-1268020 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:F6XYSW2/X7BvtDjU/1wBBa8jhTM9606 rogid:fdx3lE51+yZ1k3uwh8/LDKJC+CQ9606 rigid:CMVUj+/XkV1BcKwGN7UTNMxXN30 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P29375 uniprotkb:Q16576 intact:EBI-1560836|uniprotkb:Q86XZ1|uniprotkb:A8MV76|uniprotkb:Q4LE72|ensembl:ENSP00000382688 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 psi-mi:kdm5a_human(display_long)|uniprotkb:Jumonji/ARID domain-containing protein 1A(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2(gene name synonym)|uniprotkb:KDM5A(gene name)|psi-mi:KDM5A(display_short)|uniprotkb:RBBP2(gene name synonym)|uniprotkb:RBP2(gene name synonym)|uniprotkb:JARID1A(gene name synonym)|uniprotkb:Histone demethylase JARID1A(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5A"(gene name synonym) psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480200|imex:IM-26985-409 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036068.1|dip:DIP-472N|ensembl:ENSG00000073614(gene)|ensembl:ENST00000399788(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051213"(dioxygenase activity)|go:"GO:1901726"(negative regulation of histone deacetylase activity)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:P29375|rcsb pdb:2JXJ|rcsb pdb:2KGG|rcsb pdb:2KGI|rcsb pdb:3GL6|rcsb pdb:5C11|rcsb pdb:5CEH|rcsb pdb:5E6H|rcsb pdb:5ISL|rcsb pdb:5IVB|rcsb pdb:5IVC|rcsb pdb:5IVE|rcsb pdb:5IVF|rcsb pdb:5IVJ|rcsb pdb:5IVV|rcsb pdb:5IVY|rcsb pdb:5IW0|rcsb pdb:5IWF|rcsb pdb:5K4L|rcsb pdb:5V9P|rcsb pdb:5V9T|rcsb pdb:6BGU|rcsb pdb:6BGV|rcsb pdb:6BGW|rcsb pdb:6BGX|rcsb pdb:6BGY|rcsb pdb:6BGZ|rcsb pdb:6BH0|rcsb pdb:6BH1|rcsb pdb:6BH2|rcsb pdb:6BH3|rcsb pdb:6BH4|rcsb pdb:6BH5|rcsb pdb:6DQ4|rcsb pdb:6DQ5|rcsb pdb:6DQ6|rcsb pdb:6DQ7|rcsb pdb:6DQ8|rcsb pdb:6DQ9|rcsb pdb:6DQA|rcsb pdb:6DQB|rcsb pdb:6DQC|rcsb pdb:6DQD|rcsb pdb:6DQE|rcsb pdb:6DQF|rcsb pdb:7KLO|rcsb pdb:7KLR|reactome:R-HSA-3214842 refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:F6XYSW2/X7BvtDjU/1wBBa8jhTM9606 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rigid:CMVUj+/XkV1BcKwGN7UTNMxXN30 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P29375 uniprotkb:Q15014 intact:EBI-1560836|uniprotkb:Q86XZ1|uniprotkb:A8MV76|uniprotkb:Q4LE72|ensembl:ENSP00000382688 intact:EBI-399257|uniprotkb:B3KP92|uniprotkb:Q567V0|uniprotkb:Q8J026|uniprotkb:D3DXA5|ensembl:ENSP00000353643|ensembl:ENSP00000391969|ensembl:ENSP00000410532|ensembl:ENSP00000415476 psi-mi:kdm5a_human(display_long)|uniprotkb:Jumonji/ARID domain-containing protein 1A(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2(gene name synonym)|uniprotkb:KDM5A(gene name)|psi-mi:KDM5A(display_short)|uniprotkb:RBBP2(gene name synonym)|uniprotkb:RBP2(gene name synonym)|uniprotkb:JARID1A(gene name synonym)|uniprotkb:Histone demethylase JARID1A(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5A"(gene name synonym) psi-mi:mo4l2_human(display_long)|uniprotkb:MORF4L2(gene name)|psi-mi:MORF4L2(display_short)|uniprotkb:KIAA0026(gene name synonym)|uniprotkb:MRGX(gene name synonym)|uniprotkb:MORF-related gene X protein(gene name synonym)|uniprotkb:Transcription factor-like protein MRGX(gene name synonym)|uniprotkb:Protein MSL3-2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480200|imex:IM-26985-409 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036068.1|dip:DIP-472N|ensembl:ENSG00000073614(gene)|ensembl:ENST00000399788(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051213"(dioxygenase activity)|go:"GO:1901726"(negative regulation of histone deacetylase activity)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:P29375|rcsb pdb:2JXJ|rcsb pdb:2KGG|rcsb pdb:2KGI|rcsb pdb:3GL6|rcsb pdb:5C11|rcsb pdb:5CEH|rcsb pdb:5E6H|rcsb pdb:5ISL|rcsb pdb:5IVB|rcsb pdb:5IVC|rcsb pdb:5IVE|rcsb pdb:5IVF|rcsb pdb:5IVJ|rcsb pdb:5IVV|rcsb pdb:5IVY|rcsb pdb:5IW0|rcsb pdb:5IWF|rcsb pdb:5K4L|rcsb pdb:5V9P|rcsb pdb:5V9T|rcsb pdb:6BGU|rcsb pdb:6BGV|rcsb pdb:6BGW|rcsb pdb:6BGX|rcsb pdb:6BGY|rcsb pdb:6BGZ|rcsb pdb:6BH0|rcsb pdb:6BH1|rcsb pdb:6BH2|rcsb pdb:6BH3|rcsb pdb:6BH4|rcsb pdb:6BH5|rcsb pdb:6DQ4|rcsb pdb:6DQ5|rcsb pdb:6DQ6|rcsb pdb:6DQ7|rcsb pdb:6DQ8|rcsb pdb:6DQ9|rcsb pdb:6DQA|rcsb pdb:6DQB|rcsb pdb:6DQC|rcsb pdb:6DQD|rcsb pdb:6DQE|rcsb pdb:6DQF|rcsb pdb:7KLO|rcsb pdb:7KLR|reactome:R-HSA-3214842 refseq:NP_001135894.1|refseq:NP_001135895.1|refseq:NP_001135896.1|refseq:NP_001135897.1|refseq:NP_001135898.1|refseq:NP_001135899.1|refseq:NP_001135900.1|refseq:NP_001135901.1|refseq:NP_001135902.1|refseq:NP_001135903.1|refseq:NP_001135904.1|refseq:NP_036418.1|refseq:NP_001135890.1|refseq:NP_001135891.1|refseq:NP_001135892.1|refseq:NP_001135893.1|ensembl:ENSG00000123562(gene)|ensembl:ENST00000360458(transcript)|ensembl:ENST00000433176(transcript)|ensembl:ENST00000441076(transcript)|ensembl:ENST00000451301(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006342"|go:"GO:0016573"(histone acetylation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051155"(positive regulation of striated muscle cell differentiation)|interpro:IPR008676(MRG)|interpro:IPR026541|interpro:IPR038012|interpro:IPR038217|mint:Q15014|reactome:R-HSA-3214847 - - comment:"author score: 59" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:F6XYSW2/X7BvtDjU/1wBBa8jhTM9606 rogid:7SlnJWNVhfdzirTHBEseWbJQjyU9606 rigid:CMVUj+/XkV1BcKwGN7UTNMxXN30 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P29375 uniprotkb:O75182 intact:EBI-1560836|uniprotkb:Q86XZ1|uniprotkb:A8MV76|uniprotkb:Q4LE72|ensembl:ENSP00000382688 intact:EBI-540462|uniprotkb:Q68GC2|uniprotkb:Q6P4B8|uniprotkb:Q8TB34|uniprotkb:Q9BSC8|uniprotkb:Q2NL91|ensembl:ENSP00000369131 psi-mi:kdm5a_human(display_long)|uniprotkb:Jumonji/ARID domain-containing protein 1A(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2(gene name synonym)|uniprotkb:KDM5A(gene name)|psi-mi:KDM5A(display_short)|uniprotkb:RBBP2(gene name synonym)|uniprotkb:RBP2(gene name synonym)|uniprotkb:JARID1A(gene name synonym)|uniprotkb:Histone demethylase JARID1A(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5A"(gene name synonym) psi-mi:sin3b_human(display_long)|uniprotkb:Transcriptional corepressor Sin3b(gene name synonym)|uniprotkb:Histone deacetylase complex subunit Sin3b(gene name synonym)|uniprotkb:SIN3B(gene name)|psi-mi:SIN3B(display_short)|uniprotkb:KIAA0700(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480200|imex:IM-26985-409 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036068.1|dip:DIP-472N|ensembl:ENSG00000073614(gene)|ensembl:ENST00000399788(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051213"(dioxygenase activity)|go:"GO:1901726"(negative regulation of histone deacetylase activity)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:P29375|rcsb pdb:2JXJ|rcsb pdb:2KGG|rcsb pdb:2KGI|rcsb pdb:3GL6|rcsb pdb:5C11|rcsb pdb:5CEH|rcsb pdb:5E6H|rcsb pdb:5ISL|rcsb pdb:5IVB|rcsb pdb:5IVC|rcsb pdb:5IVE|rcsb pdb:5IVF|rcsb pdb:5IVJ|rcsb pdb:5IVV|rcsb pdb:5IVY|rcsb pdb:5IW0|rcsb pdb:5IWF|rcsb pdb:5K4L|rcsb pdb:5V9P|rcsb pdb:5V9T|rcsb pdb:6BGU|rcsb pdb:6BGV|rcsb pdb:6BGW|rcsb pdb:6BGX|rcsb pdb:6BGY|rcsb pdb:6BGZ|rcsb pdb:6BH0|rcsb pdb:6BH1|rcsb pdb:6BH2|rcsb pdb:6BH3|rcsb pdb:6BH4|rcsb pdb:6BH5|rcsb pdb:6DQ4|rcsb pdb:6DQ5|rcsb pdb:6DQ6|rcsb pdb:6DQ7|rcsb pdb:6DQ8|rcsb pdb:6DQ9|rcsb pdb:6DQA|rcsb pdb:6DQB|rcsb pdb:6DQC|rcsb pdb:6DQD|rcsb pdb:6DQE|rcsb pdb:6DQF|rcsb pdb:7KLO|rcsb pdb:7KLR|reactome:R-HSA-3214842 refseq:NP_056075.1|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0030849"(autosome)|interpro:IPR003822(Paired amphipathic helix)|interpro:IPR013194(Histone deacetylase interacting)|interpro:IPR031693|go:"GO:0003682"(chromatin binding)|interpro:IPR036600|interpro:IPR039774|mint:O75182|reactome:R-HSA-400206|reactome:R-HSA-427413|reactome:R-HSA-8936459|reactome:R-HSA-9707564|ensembl:ENSG00000127511(gene)|ensembl:ENST00000379803(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000805"(X chromosome)|go:"GO:0000806"(Y chromosome)|go:"GO:0001741"(XY body)|refseq:NP_001284524.1|refseq:NP_001284526.1 - - comment:"author score: 59" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:F6XYSW2/X7BvtDjU/1wBBa8jhTM9606 rogid:ney2nq8TMh2sFxskgXr+NgNCl349606 rigid:CMVUj+/XkV1BcKwGN7UTNMxXN30 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P29375 uniprotkb:Q9UBU8 intact:EBI-1560836|uniprotkb:Q86XZ1|uniprotkb:A8MV76|uniprotkb:Q4LE72|ensembl:ENSP00000382688 intact:EBI-399246|uniprotkb:O95899|uniprotkb:Q5QTS1|uniprotkb:Q6NVX8|uniprotkb:Q86YT7|uniprotkb:Q9HBP6|uniprotkb:Q9NSW5|uniprotkb:B4DKN6|uniprotkb:D3DW88|ensembl:ENSP00000331310|uniprotkb:B7Z6R1 psi-mi:kdm5a_human(display_long)|uniprotkb:Jumonji/ARID domain-containing protein 1A(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2(gene name synonym)|uniprotkb:KDM5A(gene name)|psi-mi:KDM5A(display_short)|uniprotkb:RBBP2(gene name synonym)|uniprotkb:RBP2(gene name synonym)|uniprotkb:JARID1A(gene name synonym)|uniprotkb:Histone demethylase JARID1A(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5A"(gene name synonym) psi-mi:mo4l1_human(display_long)|uniprotkb:HSPC008(orf name)|uniprotkb:HSPC061(orf name)|uniprotkb:PP368(orf name)|uniprotkb:MORF4L1(gene name)|psi-mi:MORF4L1(display_short)|uniprotkb:MRG15(gene name synonym)|uniprotkb:MORF-related gene 15 protein(gene name synonym)|uniprotkb:Transcription factor-like protein MRG15(gene name synonym)|uniprotkb:Protein MSL3-1(gene name synonym)|uniprotkb:FWP006(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480200|imex:IM-26985-409 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036068.1|dip:DIP-472N|ensembl:ENSG00000073614(gene)|ensembl:ENST00000399788(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051213"(dioxygenase activity)|go:"GO:1901726"(negative regulation of histone deacetylase activity)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:P29375|rcsb pdb:2JXJ|rcsb pdb:2KGG|rcsb pdb:2KGI|rcsb pdb:3GL6|rcsb pdb:5C11|rcsb pdb:5CEH|rcsb pdb:5E6H|rcsb pdb:5ISL|rcsb pdb:5IVB|rcsb pdb:5IVC|rcsb pdb:5IVE|rcsb pdb:5IVF|rcsb pdb:5IVJ|rcsb pdb:5IVV|rcsb pdb:5IVY|rcsb pdb:5IW0|rcsb pdb:5IWF|rcsb pdb:5K4L|rcsb pdb:5V9P|rcsb pdb:5V9T|rcsb pdb:6BGU|rcsb pdb:6BGV|rcsb pdb:6BGW|rcsb pdb:6BGX|rcsb pdb:6BGY|rcsb pdb:6BGZ|rcsb pdb:6BH0|rcsb pdb:6BH1|rcsb pdb:6BH2|rcsb pdb:6BH3|rcsb pdb:6BH4|rcsb pdb:6BH5|rcsb pdb:6DQ4|rcsb pdb:6DQ5|rcsb pdb:6DQ6|rcsb pdb:6DQ7|rcsb pdb:6DQ8|rcsb pdb:6DQ9|rcsb pdb:6DQA|rcsb pdb:6DQB|rcsb pdb:6DQC|rcsb pdb:6DQD|rcsb pdb:6DQE|rcsb pdb:6DQF|rcsb pdb:7KLO|rcsb pdb:7KLR|reactome:R-HSA-3214842 refseq:NP_006782.1|refseq:NP_996670.1|dip:DIP-29017N|refseq:NP_001252532.1|refseq:NP_001252533.1|refseq:NP_001252534.1|ensembl:ENSG00000185787(gene)|ensembl:ENST00000331268(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0016573"(histone acetylation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR008676(MRG)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR026541|interpro:IPR038011|interpro:IPR038217|mint:Q9UBU8|rcsb pdb:2AQL|rcsb pdb:2EFI|rcsb pdb:2F5J|rcsb pdb:2F5K|rcsb pdb:2LKM|rcsb pdb:2N1D|rcsb pdb:6AGO|rcsb pdb:6INE|reactome:R-HSA-3214847 - - comment:"author score: 72" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:F6XYSW2/X7BvtDjU/1wBBa8jhTM9606 rogid:28GQifqUMxwR32cneTXH+lpW4gM9606 rigid:CMVUj+/XkV1BcKwGN7UTNMxXN30 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P29375 uniprotkb:Q7Z589 intact:EBI-1560836|uniprotkb:Q86XZ1|uniprotkb:A8MV76|uniprotkb:Q4LE72|ensembl:ENSP00000382688 intact:EBI-6598631|ensembl:ENSP00000334130|ensembl:ENSP00000432327|uniprotkb:Q4G109|uniprotkb:Q8NBU6|uniprotkb:Q8TE50|uniprotkb:Q9H8I9|uniprotkb:Q9NRH0|uniprotkb:B7ZKU0|uniprotkb:B7ZKT8|uniprotkb:B7ZKU2|uniprotkb:Q17RM7 psi-mi:kdm5a_human(display_long)|uniprotkb:Jumonji/ARID domain-containing protein 1A(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2(gene name synonym)|uniprotkb:KDM5A(gene name)|psi-mi:KDM5A(display_short)|uniprotkb:RBBP2(gene name synonym)|uniprotkb:RBP2(gene name synonym)|uniprotkb:JARID1A(gene name synonym)|uniprotkb:Histone demethylase JARID1A(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5A"(gene name synonym) psi-mi:emsy_human(display_long)|uniprotkb:EMSY(gene name)|psi-mi:EMSY(display_short)|uniprotkb:C11orf30(gene name synonym)|uniprotkb:GL002(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480200|imex:IM-26985-409 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036068.1|dip:DIP-472N|ensembl:ENSG00000073614(gene)|ensembl:ENST00000399788(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051213"(dioxygenase activity)|go:"GO:1901726"(negative regulation of histone deacetylase activity)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:P29375|rcsb pdb:2JXJ|rcsb pdb:2KGG|rcsb pdb:2KGI|rcsb pdb:3GL6|rcsb pdb:5C11|rcsb pdb:5CEH|rcsb pdb:5E6H|rcsb pdb:5ISL|rcsb pdb:5IVB|rcsb pdb:5IVC|rcsb pdb:5IVE|rcsb pdb:5IVF|rcsb pdb:5IVJ|rcsb pdb:5IVV|rcsb pdb:5IVY|rcsb pdb:5IW0|rcsb pdb:5IWF|rcsb pdb:5K4L|rcsb pdb:5V9P|rcsb pdb:5V9T|rcsb pdb:6BGU|rcsb pdb:6BGV|rcsb pdb:6BGW|rcsb pdb:6BGX|rcsb pdb:6BGY|rcsb pdb:6BGZ|rcsb pdb:6BH0|rcsb pdb:6BH1|rcsb pdb:6BH2|rcsb pdb:6BH3|rcsb pdb:6BH4|rcsb pdb:6BH5|rcsb pdb:6DQ4|rcsb pdb:6DQ5|rcsb pdb:6DQ6|rcsb pdb:6DQ7|rcsb pdb:6DQ8|rcsb pdb:6DQ9|rcsb pdb:6DQA|rcsb pdb:6DQB|rcsb pdb:6DQC|rcsb pdb:6DQD|rcsb pdb:6DQE|rcsb pdb:6DQF|rcsb pdb:7KLO|rcsb pdb:7KLR|reactome:R-HSA-3214842 refseq:NP_001287871.1|refseq:NP_001287872.1|refseq:NP_001287873.1|ensembl:ENST00000334736(transcript)|ensembl:ENST00000529032(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0042802"(identical protein binding)|interpro:IPR005491(ENT)|interpro:IPR033482|interpro:IPR036142|mint:Q7Z589|rcsb pdb:1UTU|ensembl:ENSG00000158636(gene)|rcsb pdb:1UZ3|rcsb pdb:2FMM|refseq:NP_064578.2|ensembl:ENSP00000433634|ensembl:ENST00000533988|ensembl:ENSP00000434665|ensembl:ENSP00000334130|ensembl:ENST00000524767|ensembl:ENSP00000433205|ensembl:ENST00000525038|ensembl:ENSP00000436968|ensembl:ENST00000525919|ensembl:ENSP00000432010|ensembl:ENSP00000432327|ensembl:ENST00000533248|dip:DIP-29099N - - comment:"author score: 75" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:F6XYSW2/X7BvtDjU/1wBBa8jhTM9606 rogid:AlagiKsle+RG5HUine4x/QddsJc9606 rigid:CMVUj+/XkV1BcKwGN7UTNMxXN30 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P29375 uniprotkb:Q96QT6 intact:EBI-1560836|uniprotkb:Q86XZ1|uniprotkb:A8MV76|uniprotkb:Q4LE72|ensembl:ENSP00000382688 intact:EBI-2803760|uniprotkb:Q9BV34|uniprotkb:Q9P205|uniprotkb:Q6ZML2|uniprotkb:Q0VAI5|uniprotkb:Q9H7U9|ensembl:ENSP00000329933|uniprotkb:Q2TAK2 psi-mi:kdm5a_human(display_long)|uniprotkb:Jumonji/ARID domain-containing protein 1A(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2(gene name synonym)|uniprotkb:KDM5A(gene name)|psi-mi:KDM5A(display_short)|uniprotkb:RBBP2(gene name synonym)|uniprotkb:RBP2(gene name synonym)|uniprotkb:JARID1A(gene name synonym)|uniprotkb:Histone demethylase JARID1A(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5A"(gene name synonym) psi-mi:phf12_human(display_long)|uniprotkb:KIAA1523(gene name synonym)|uniprotkb:PHD factor 1(gene name synonym)|uniprotkb:PHF12(gene name)|psi-mi:PHF12(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480200|imex:IM-26985-409 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036068.1|dip:DIP-472N|ensembl:ENSG00000073614(gene)|ensembl:ENST00000399788(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051213"(dioxygenase activity)|go:"GO:1901726"(negative regulation of histone deacetylase activity)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:P29375|rcsb pdb:2JXJ|rcsb pdb:2KGG|rcsb pdb:2KGI|rcsb pdb:3GL6|rcsb pdb:5C11|rcsb pdb:5CEH|rcsb pdb:5E6H|rcsb pdb:5ISL|rcsb pdb:5IVB|rcsb pdb:5IVC|rcsb pdb:5IVE|rcsb pdb:5IVF|rcsb pdb:5IVJ|rcsb pdb:5IVV|rcsb pdb:5IVY|rcsb pdb:5IW0|rcsb pdb:5IWF|rcsb pdb:5K4L|rcsb pdb:5V9P|rcsb pdb:5V9T|rcsb pdb:6BGU|rcsb pdb:6BGV|rcsb pdb:6BGW|rcsb pdb:6BGX|rcsb pdb:6BGY|rcsb pdb:6BGZ|rcsb pdb:6BH0|rcsb pdb:6BH1|rcsb pdb:6BH2|rcsb pdb:6BH3|rcsb pdb:6BH4|rcsb pdb:6BH5|rcsb pdb:6DQ4|rcsb pdb:6DQ5|rcsb pdb:6DQ6|rcsb pdb:6DQ7|rcsb pdb:6DQ8|rcsb pdb:6DQ9|rcsb pdb:6DQA|rcsb pdb:6DQB|rcsb pdb:6DQC|rcsb pdb:6DQD|rcsb pdb:6DQE|rcsb pdb:6DQF|rcsb pdb:7KLO|rcsb pdb:7KLR|reactome:R-HSA-3214842 refseq:NP_001028733.1|refseq:NP_065940.1|ensembl:ENSG00000109118(gene)|ensembl:ENST00000332830(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016580"(Sin3 complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070822"(Sin3-type complex)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR031966|interpro:IPR038098|interpro:IPR042163|mint:Q96QT6|rcsb pdb:2L9S|rcsb pdb:2LKM|refseq:NP_001277060.1|dip:DIP-59632N - - comment:"author score: 80" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:F6XYSW2/X7BvtDjU/1wBBa8jhTM9606 rogid:PSctZ9CGOcztlg6VdcB1jkIOhjo9606 rigid:CMVUj+/XkV1BcKwGN7UTNMxXN30 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P29375 uniprotkb:Q8WUU5 intact:EBI-1560836|uniprotkb:Q86XZ1|uniprotkb:A8MV76|uniprotkb:Q4LE72|ensembl:ENSP00000382688 intact:EBI-3916882|uniprotkb:D6W5Q5|uniprotkb:Q9H689|uniprotkb:Q8N5Y5|uniprotkb:Q99995|uniprotkb:B2RE37|ensembl:ENSP00000287957 psi-mi:kdm5a_human(display_long)|uniprotkb:Jumonji/ARID domain-containing protein 1A(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 2(gene name synonym)|uniprotkb:KDM5A(gene name)|psi-mi:KDM5A(display_short)|uniprotkb:RBBP2(gene name synonym)|uniprotkb:RBP2(gene name synonym)|uniprotkb:JARID1A(gene name synonym)|uniprotkb:Histone demethylase JARID1A(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(4) demethylase 5A"(gene name synonym) psi-mi:gatd1_human(display_long)|uniprotkb:GATAD1(gene name)|psi-mi:GATAD1(display_short)|uniprotkb:ODAG(gene name synonym)|uniprotkb:Ocular development-associated gene protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480200|imex:IM-26985-409 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036068.1|dip:DIP-472N|ensembl:ENSG00000073614(gene)|ensembl:ENST00000399788(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008584"(male gonad development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034647"(histone H3-tri/di/monomethyl-lysine-4 demethylase activity)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051090"(regulation of DNA-binding transcription factor activity)|go:"GO:0051213"(dioxygenase activity)|go:"GO:1901726"(negative regulation of histone deacetylase activity)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|interpro:IPR004198(Zinc finger, C5HC2-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013637(PLU-1-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036431|mint:P29375|rcsb pdb:2JXJ|rcsb pdb:2KGG|rcsb pdb:2KGI|rcsb pdb:3GL6|rcsb pdb:5C11|rcsb pdb:5CEH|rcsb pdb:5E6H|rcsb pdb:5ISL|rcsb pdb:5IVB|rcsb pdb:5IVC|rcsb pdb:5IVE|rcsb pdb:5IVF|rcsb pdb:5IVJ|rcsb pdb:5IVV|rcsb pdb:5IVY|rcsb pdb:5IW0|rcsb pdb:5IWF|rcsb pdb:5K4L|rcsb pdb:5V9P|rcsb pdb:5V9T|rcsb pdb:6BGU|rcsb pdb:6BGV|rcsb pdb:6BGW|rcsb pdb:6BGX|rcsb pdb:6BGY|rcsb pdb:6BGZ|rcsb pdb:6BH0|rcsb pdb:6BH1|rcsb pdb:6BH2|rcsb pdb:6BH3|rcsb pdb:6BH4|rcsb pdb:6BH5|rcsb pdb:6DQ4|rcsb pdb:6DQ5|rcsb pdb:6DQ6|rcsb pdb:6DQ7|rcsb pdb:6DQ8|rcsb pdb:6DQ9|rcsb pdb:6DQA|rcsb pdb:6DQB|rcsb pdb:6DQC|rcsb pdb:6DQD|rcsb pdb:6DQE|rcsb pdb:6DQF|rcsb pdb:7KLO|rcsb pdb:7KLR|reactome:R-HSA-3214842 refseq:NP_066990.3|ensembl:ENSG00000157259(gene)|ensembl:ENST00000287957(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR039050|mint:Q8WUU5 - - comment:"author score: 107" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:F6XYSW2/X7BvtDjU/1wBBa8jhTM9606 rogid:mwq5yOlZTelKYR0VGr822k9K0Nk9606 rigid:CMVUj+/XkV1BcKwGN7UTNMxXN30 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6B0I6 uniprotkb:P56270 intact:EBI-4311651|uniprotkb:Q9NW76|uniprotkb:B3KPC4|uniprotkb:Q9NT41|uniprotkb:Q0VF39|ensembl:ENSP00000334181|ensembl:ENSP00000460897|ensembl:ENSP00000482224 intact:EBI-1809742|uniprotkb:A8QJL9|uniprotkb:Q15703|uniprotkb:Q99443|uniprotkb:H3BQD6|uniprotkb:G5E927|uniprotkb:Q8NFN7|uniprotkb:C6G496|ensembl:ENSP00000313362 psi-mi:kdm4d_human(display_long)|uniprotkb:KDM4D(gene name)|psi-mi:KDM4D(display_short)|uniprotkb:JHDM3D(gene name synonym)|uniprotkb:JMJD2D(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3D(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2D(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4D"(gene name synonym) psi-mi:maz_human(display_long)|uniprotkb:Transcription factor Zif87(gene name synonym)|uniprotkb:Zinc finger protein 801(gene name synonym)|uniprotkb:MAZ(gene name)|psi-mi:MAZ(display_short)|uniprotkb:Purine-binding transcription factor(gene name synonym)|uniprotkb:Pur-1(gene name synonym)|uniprotkb:ZF87(gene name synonym)|uniprotkb:ZNF801(gene name synonym)|uniprotkb:Serum amyloid A-activating factor-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480104|imex:IM-26985-481 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060509.2|rcsb pdb:5PI6|rcsb pdb:5PI7|rcsb pdb:5PI8|rcsb pdb:5PI9|rcsb pdb:5PIA|rcsb pdb:5PIB|rcsb pdb:5PIC|rcsb pdb:5PID|rcsb pdb:5PIE|rcsb pdb:5PIF|rcsb pdb:5PIG|rcsb pdb:5PIH|rcsb pdb:5PII|rcsb pdb:5PIJ|rcsb pdb:5PIK|rcsb pdb:5PIL|rcsb pdb:5PIM|rcsb pdb:5PIN|rcsb pdb:5PIO|rcsb pdb:5PIP|rcsb pdb:5PIQ|rcsb pdb:5PIR|rcsb pdb:5PIS|rcsb pdb:5PIT|rcsb pdb:5PIU|rcsb pdb:5PIV|rcsb pdb:5PIW|rcsb pdb:5PIX|rcsb pdb:5PIY|rcsb pdb:5PIZ|rcsb pdb:5PJ0|rcsb pdb:5PI5|rcsb pdb:5PJ1|rcsb pdb:5PJ2|rcsb pdb:5PJ3|rcsb pdb:5PJ4|rcsb pdb:5PJ6|rcsb pdb:5PJ7|rcsb pdb:5PJ8|rcsb pdb:5PJ9|rcsb pdb:5PJA|rcsb pdb:5PJB|rcsb pdb:5PJC|rcsb pdb:5PJD|rcsb pdb:5PJE|rcsb pdb:5PJF|rcsb pdb:5PJG|rcsb pdb:5PJ5|rcsb pdb:5PJH|rcsb pdb:5PJI|rcsb pdb:5PJJ|rcsb pdb:5PJK|rcsb pdb:5PJL|rcsb pdb:5PJM|rcsb pdb:5PJN|rcsb pdb:5PJO|rcsb pdb:5PJP|rcsb pdb:5PJQ|rcsb pdb:5PJR|rcsb pdb:5PJS|rcsb pdb:6ETT|rcsb pdb:6ETU|rcsb pdb:5PJT|rcsb pdb:6ETV|rcsb pdb:6ETW|rcsb pdb:6F5Q|rcsb pdb:6F5R|rcsb pdb:6F5S|rcsb pdb:6F5T|rcsb pdb:6H0W|rcsb pdb:6H0X|rcsb pdb:6H0Y|rcsb pdb:6H0Z|rcsb pdb:6H10|rcsb pdb:6H11|reactome:R-HSA-3214842|ensembl:ENSG00000186280(gene)|ensembl:ENST00000335080(transcript)|ensembl:ENST00000536741(transcript)|ensembl:ENST00000610872(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|rcsb pdb:5PJV|rcsb pdb:5PJW|rcsb pdb:5PJX|rcsb pdb:5PJY|rcsb pdb:5PJZ|rcsb pdb:5PK0|rcsb pdb:5PK1|rcsb pdb:5PK2|rcsb pdb:5PJU|rcsb pdb:5PK3|rcsb pdb:5PK4|rcsb pdb:5PK5|rcsb pdb:5PK6|rcsb pdb:5PK7|rcsb pdb:5PK8|rcsb pdb:5PK9|rcsb pdb:5PKA|rcsb pdb:5PKB|rcsb pdb:5PKC|rcsb pdb:5PKD|rcsb pdb:5PKE|rcsb pdb:5PKF|rcsb pdb:5PKG|rcsb pdb:5PKH|rcsb pdb:5PKI|rcsb pdb:5PKJ|rcsb pdb:5PKK|rcsb pdb:5PKL|rcsb pdb:5PKM|rcsb pdb:5PKN|rcsb pdb:5PKO|rcsb pdb:5PKP|rcsb pdb:5PKQ|rcsb pdb:5PKR|rcsb pdb:5PKS|rcsb pdb:5PKT|rcsb pdb:5PKU|rcsb pdb:5PKV|rcsb pdb:5PKW|rcsb pdb:5PKX|rcsb pdb:5PKY|rcsb pdb:5PKZ|rcsb pdb:5PL0|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072562"(blood microparticle)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|mint:Q6B0I6|rcsb pdb:3DXT|rcsb pdb:3DXU|rcsb pdb:4D6Q|rcsb pdb:4D6R|rcsb pdb:4D6S|rcsb pdb:4HON|rcsb pdb:5PL2|rcsb pdb:5PL3|rcsb pdb:5PL1|rcsb pdb:5PL4|rcsb pdb:5PL5|rcsb pdb:5PL6|rcsb pdb:5PL7|rcsb pdb:5PL8|rcsb pdb:5PL9|rcsb pdb:5PLA|rcsb pdb:5PLB|rcsb pdb:5PLC|rcsb pdb:5PLD|rcsb pdb:5PLE|rcsb pdb:5PLF|rcsb pdb:5PLG|rcsb pdb:5PLH|rcsb pdb:5PLI|rcsb pdb:5PLJ|rcsb pdb:5PLK|rcsb pdb:5PLL|rcsb pdb:5PLM|rcsb pdb:5PLN|rcsb pdb:5PLO|rcsb pdb:5PLP|rcsb pdb:5PLQ|rcsb pdb:5PLR|rcsb pdb:5PLS|rcsb pdb:5F5A|rcsb pdb:5F5C|rcsb pdb:5FP4|rcsb pdb:5FP7|rcsb pdb:5FP8|rcsb pdb:5FP9|rcsb pdb:5FPA|rcsb pdb:5FPB|rcsb pdb:5PH0|rcsb pdb:5PH1|rcsb pdb:5PH2|rcsb pdb:5PH3|rcsb pdb:5PH4|rcsb pdb:4HOO|rcsb pdb:5PH5|rcsb pdb:5PH6|rcsb pdb:5PH7|rcsb pdb:5PH8|rcsb pdb:5PH9|rcsb pdb:5PHA|rcsb pdb:5PHB|rcsb pdb:5PHC|rcsb pdb:5PHD|rcsb pdb:5PHE|rcsb pdb:5PLU|rcsb pdb:5PLV|rcsb pdb:5PLW|rcsb pdb:5PLX|rcsb pdb:5PLY|rcsb pdb:5PLZ|rcsb pdb:5PM0|rcsb pdb:5PM1|rcsb pdb:5PM2|rcsb pdb:5PM3|rcsb pdb:5PM4|rcsb pdb:5PM5|rcsb pdb:5PM6|rcsb pdb:5PM7|rcsb pdb:5PM8|rcsb pdb:5PM9|rcsb pdb:5PMA|rcsb pdb:5PMB|rcsb pdb:5PMC|rcsb pdb:5PMD|rcsb pdb:5PME|rcsb pdb:5PMF|rcsb pdb:5PMG|rcsb pdb:5PMH|rcsb pdb:5PMI|rcsb pdb:5PMJ|rcsb pdb:5PMK|rcsb pdb:5PML|rcsb pdb:5PMM|rcsb pdb:5PMN|rcsb pdb:5PMO|rcsb pdb:5PMP|rcsb pdb:5PMQ|rcsb pdb:5PMR|rcsb pdb:5PMS|rcsb pdb:5PMT|rcsb pdb:5PMU|rcsb pdb:5PMV|rcsb pdb:5PMW|rcsb pdb:5PMX|rcsb pdb:5PMY|rcsb pdb:5PMZ|rcsb pdb:5PN0|rcsb pdb:5PN1|rcsb pdb:5PN2|rcsb pdb:5PN3|rcsb pdb:5PN4|rcsb pdb:5PN5|rcsb pdb:5PN6|rcsb pdb:5PN7|rcsb pdb:5PN8|rcsb pdb:5PN9|rcsb pdb:5PNA|rcsb pdb:5PNB|rcsb pdb:5PNC|rcsb pdb:5PND|rcsb pdb:5PNE|rcsb pdb:5PNF|rcsb pdb:5PNG|rcsb pdb:5PNH|rcsb pdb:5PNI|rcsb pdb:5PNJ|rcsb pdb:5PNK|rcsb pdb:5PNL|rcsb pdb:5PNM|rcsb pdb:5PLT|rcsb pdb:5PNN|rcsb pdb:5PNO|rcsb pdb:5PNP|rcsb pdb:5PNQ|rcsb pdb:5PNR|rcsb pdb:5PNS|rcsb pdb:5PNU|rcsb pdb:5PNV|rcsb pdb:5PNW|rcsb pdb:6ETE|rcsb pdb:6ETG|rcsb pdb:6ETS|rcsb pdb:5PHJ|rcsb pdb:5PHK|rcsb pdb:5PHL|rcsb pdb:5PHM|rcsb pdb:5PHN|rcsb pdb:5PHO|rcsb pdb:5PHP|rcsb pdb:5PHQ|rcsb pdb:5PHR|rcsb pdb:5PHS|rcsb pdb:5PHT|rcsb pdb:5PHU|rcsb pdb:5PHV|rcsb pdb:5PHF|rcsb pdb:5PHG|rcsb pdb:5PHH|rcsb pdb:5PHI|rcsb pdb:5PHW|rcsb pdb:5PHX|rcsb pdb:5PHY|rcsb pdb:5PHZ|rcsb pdb:5PI0|rcsb pdb:5PI1|rcsb pdb:5PI2|rcsb pdb:5PI3|rcsb pdb:5PI4|dip:DIP-29606N refseq:NP_002374.2|refseq:NP_001036004.1|refseq:NP_001263205.1|refseq:NP_001263204.1|ensembl:ENSG00000103495(gene)|ensembl:ENST00000322945(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:P56270 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:svQfKWBCSAPSGFAV5YPZXFvcqkk9606 rogid:zuCDXhF2wr8gmTyjBNse9kVUqSw9606 rigid:7fqj2Gju3X4HbV0gQNAzWx9cUhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6B0I6 uniprotkb:Q9UKV8 intact:EBI-4311651|uniprotkb:Q9NW76|uniprotkb:B3KPC4|uniprotkb:Q9NT41|uniprotkb:Q0VF39|ensembl:ENSP00000334181|ensembl:ENSP00000460897|ensembl:ENSP00000482224 intact:EBI-528269|uniprotkb:Q8TCZ5|uniprotkb:Q8WV58|uniprotkb:Q96ID1|ensembl:ENSP00000220592 psi-mi:kdm4d_human(display_long)|uniprotkb:KDM4D(gene name)|psi-mi:KDM4D(display_short)|uniprotkb:JHDM3D(gene name synonym)|uniprotkb:JMJD2D(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3D(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2D(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4D"(gene name synonym) psi-mi:ago2_human(display_long)|uniprotkb:AGO2(gene name)|psi-mi:AGO2(display_short)|uniprotkb:Argonaute RISC catalytic component 2(gene name synonym)|uniprotkb:EIF2C2(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2C 2(gene name synonym)|uniprotkb:PAZ Piwi domain protein(gene name synonym)|uniprotkb:Protein slicer(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480104|imex:IM-26985-481 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060509.2|rcsb pdb:5PI6|rcsb pdb:5PI7|rcsb pdb:5PI8|rcsb pdb:5PI9|rcsb pdb:5PIA|rcsb pdb:5PIB|rcsb pdb:5PIC|rcsb pdb:5PID|rcsb pdb:5PIE|rcsb pdb:5PIF|rcsb pdb:5PIG|rcsb pdb:5PIH|rcsb pdb:5PII|rcsb pdb:5PIJ|rcsb pdb:5PIK|rcsb pdb:5PIL|rcsb pdb:5PIM|rcsb pdb:5PIN|rcsb pdb:5PIO|rcsb pdb:5PIP|rcsb pdb:5PIQ|rcsb pdb:5PIR|rcsb pdb:5PIS|rcsb pdb:5PIT|rcsb pdb:5PIU|rcsb pdb:5PIV|rcsb pdb:5PIW|rcsb pdb:5PIX|rcsb pdb:5PIY|rcsb pdb:5PIZ|rcsb pdb:5PJ0|rcsb pdb:5PI5|rcsb pdb:5PJ1|rcsb pdb:5PJ2|rcsb pdb:5PJ3|rcsb pdb:5PJ4|rcsb pdb:5PJ6|rcsb pdb:5PJ7|rcsb pdb:5PJ8|rcsb pdb:5PJ9|rcsb pdb:5PJA|rcsb pdb:5PJB|rcsb pdb:5PJC|rcsb pdb:5PJD|rcsb pdb:5PJE|rcsb pdb:5PJF|rcsb pdb:5PJG|rcsb pdb:5PJ5|rcsb pdb:5PJH|rcsb pdb:5PJI|rcsb pdb:5PJJ|rcsb pdb:5PJK|rcsb pdb:5PJL|rcsb pdb:5PJM|rcsb pdb:5PJN|rcsb pdb:5PJO|rcsb pdb:5PJP|rcsb pdb:5PJQ|rcsb pdb:5PJR|rcsb pdb:5PJS|rcsb pdb:6ETT|rcsb pdb:6ETU|rcsb pdb:5PJT|rcsb pdb:6ETV|rcsb pdb:6ETW|rcsb pdb:6F5Q|rcsb pdb:6F5R|rcsb pdb:6F5S|rcsb pdb:6F5T|rcsb pdb:6H0W|rcsb pdb:6H0X|rcsb pdb:6H0Y|rcsb pdb:6H0Z|rcsb pdb:6H10|rcsb pdb:6H11|reactome:R-HSA-3214842|ensembl:ENSG00000186280(gene)|ensembl:ENST00000335080(transcript)|ensembl:ENST00000536741(transcript)|ensembl:ENST00000610872(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|rcsb pdb:5PJV|rcsb pdb:5PJW|rcsb pdb:5PJX|rcsb pdb:5PJY|rcsb pdb:5PJZ|rcsb pdb:5PK0|rcsb pdb:5PK1|rcsb pdb:5PK2|rcsb pdb:5PJU|rcsb pdb:5PK3|rcsb pdb:5PK4|rcsb pdb:5PK5|rcsb pdb:5PK6|rcsb pdb:5PK7|rcsb pdb:5PK8|rcsb pdb:5PK9|rcsb pdb:5PKA|rcsb pdb:5PKB|rcsb pdb:5PKC|rcsb pdb:5PKD|rcsb pdb:5PKE|rcsb pdb:5PKF|rcsb pdb:5PKG|rcsb pdb:5PKH|rcsb pdb:5PKI|rcsb pdb:5PKJ|rcsb pdb:5PKK|rcsb pdb:5PKL|rcsb pdb:5PKM|rcsb pdb:5PKN|rcsb pdb:5PKO|rcsb pdb:5PKP|rcsb pdb:5PKQ|rcsb pdb:5PKR|rcsb pdb:5PKS|rcsb pdb:5PKT|rcsb pdb:5PKU|rcsb pdb:5PKV|rcsb pdb:5PKW|rcsb pdb:5PKX|rcsb pdb:5PKY|rcsb pdb:5PKZ|rcsb pdb:5PL0|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072562"(blood microparticle)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|mint:Q6B0I6|rcsb pdb:3DXT|rcsb pdb:3DXU|rcsb pdb:4D6Q|rcsb pdb:4D6R|rcsb pdb:4D6S|rcsb pdb:4HON|rcsb pdb:5PL2|rcsb pdb:5PL3|rcsb pdb:5PL1|rcsb pdb:5PL4|rcsb pdb:5PL5|rcsb pdb:5PL6|rcsb pdb:5PL7|rcsb pdb:5PL8|rcsb pdb:5PL9|rcsb pdb:5PLA|rcsb pdb:5PLB|rcsb pdb:5PLC|rcsb pdb:5PLD|rcsb pdb:5PLE|rcsb pdb:5PLF|rcsb pdb:5PLG|rcsb pdb:5PLH|rcsb pdb:5PLI|rcsb pdb:5PLJ|rcsb pdb:5PLK|rcsb pdb:5PLL|rcsb pdb:5PLM|rcsb pdb:5PLN|rcsb pdb:5PLO|rcsb pdb:5PLP|rcsb pdb:5PLQ|rcsb pdb:5PLR|rcsb pdb:5PLS|rcsb pdb:5F5A|rcsb pdb:5F5C|rcsb pdb:5FP4|rcsb pdb:5FP7|rcsb pdb:5FP8|rcsb pdb:5FP9|rcsb pdb:5FPA|rcsb pdb:5FPB|rcsb pdb:5PH0|rcsb pdb:5PH1|rcsb pdb:5PH2|rcsb pdb:5PH3|rcsb pdb:5PH4|rcsb pdb:4HOO|rcsb pdb:5PH5|rcsb pdb:5PH6|rcsb pdb:5PH7|rcsb pdb:5PH8|rcsb pdb:5PH9|rcsb pdb:5PHA|rcsb pdb:5PHB|rcsb pdb:5PHC|rcsb pdb:5PHD|rcsb pdb:5PHE|rcsb pdb:5PLU|rcsb pdb:5PLV|rcsb pdb:5PLW|rcsb pdb:5PLX|rcsb pdb:5PLY|rcsb pdb:5PLZ|rcsb pdb:5PM0|rcsb pdb:5PM1|rcsb pdb:5PM2|rcsb pdb:5PM3|rcsb pdb:5PM4|rcsb pdb:5PM5|rcsb pdb:5PM6|rcsb pdb:5PM7|rcsb pdb:5PM8|rcsb pdb:5PM9|rcsb pdb:5PMA|rcsb pdb:5PMB|rcsb pdb:5PMC|rcsb pdb:5PMD|rcsb pdb:5PME|rcsb pdb:5PMF|rcsb pdb:5PMG|rcsb pdb:5PMH|rcsb pdb:5PMI|rcsb pdb:5PMJ|rcsb pdb:5PMK|rcsb pdb:5PML|rcsb pdb:5PMM|rcsb pdb:5PMN|rcsb pdb:5PMO|rcsb pdb:5PMP|rcsb pdb:5PMQ|rcsb pdb:5PMR|rcsb pdb:5PMS|rcsb pdb:5PMT|rcsb pdb:5PMU|rcsb pdb:5PMV|rcsb pdb:5PMW|rcsb pdb:5PMX|rcsb pdb:5PMY|rcsb pdb:5PMZ|rcsb pdb:5PN0|rcsb pdb:5PN1|rcsb pdb:5PN2|rcsb pdb:5PN3|rcsb pdb:5PN4|rcsb pdb:5PN5|rcsb pdb:5PN6|rcsb pdb:5PN7|rcsb pdb:5PN8|rcsb pdb:5PN9|rcsb pdb:5PNA|rcsb pdb:5PNB|rcsb pdb:5PNC|rcsb pdb:5PND|rcsb pdb:5PNE|rcsb pdb:5PNF|rcsb pdb:5PNG|rcsb pdb:5PNH|rcsb pdb:5PNI|rcsb pdb:5PNJ|rcsb pdb:5PNK|rcsb pdb:5PNL|rcsb pdb:5PNM|rcsb pdb:5PLT|rcsb pdb:5PNN|rcsb pdb:5PNO|rcsb pdb:5PNP|rcsb pdb:5PNQ|rcsb pdb:5PNR|rcsb pdb:5PNS|rcsb pdb:5PNU|rcsb pdb:5PNV|rcsb pdb:5PNW|rcsb pdb:6ETE|rcsb pdb:6ETG|rcsb pdb:6ETS|rcsb pdb:5PHJ|rcsb pdb:5PHK|rcsb pdb:5PHL|rcsb pdb:5PHM|rcsb pdb:5PHN|rcsb pdb:5PHO|rcsb pdb:5PHP|rcsb pdb:5PHQ|rcsb pdb:5PHR|rcsb pdb:5PHS|rcsb pdb:5PHT|rcsb pdb:5PHU|rcsb pdb:5PHV|rcsb pdb:5PHF|rcsb pdb:5PHG|rcsb pdb:5PHH|rcsb pdb:5PHI|rcsb pdb:5PHW|rcsb pdb:5PHX|rcsb pdb:5PHY|rcsb pdb:5PHZ|rcsb pdb:5PI0|rcsb pdb:5PI1|rcsb pdb:5PI2|rcsb pdb:5PI3|rcsb pdb:5PI4|dip:DIP-29606N refseq:NP_001158095.1|refseq:NP_036286.2|rcsb pdb:5T7B|rcsb pdb:5WEA|rcsb pdb:6CBD|rcsb pdb:6MDZ|rcsb pdb:6MFN|rcsb pdb:6MFR|rcsb pdb:6N4O|rcsb pdb:6NIT|rcsb pdb:6RA4|rcsb pdb:7C6B|rcsb pdb:7D7U|reactome:R-HSA-1912408|reactome:R-HSA-203927|reactome:R-HSA-4086398|reactome:R-HSA-426486|reactome:R-HSA-426496|reactome:R-HSA-5578749|reactome:R-HSA-5628897|reactome:R-HSA-5687128|reactome:R-HSA-8934593|reactome:R-HSA-8943723|reactome:R-HSA-8948700|reactome:R-HSA-8986944|reactome:R-HSA-9018519|reactome:R-HSA-9022692|reactome:R-HSA-9029569|rcsb pdb:4F3T|rcsb pdb:4OLA|rcsb pdb:4OLB|rcsb pdb:4W5N|rcsb pdb:4W5O|rcsb pdb:4W5Q|rcsb pdb:4W5R|rcsb pdb:4W5T|rcsb pdb:4Z4C|rcsb pdb:4Z4D|rcsb pdb:4Z4E|rcsb pdb:4Z4F|rcsb pdb:4Z4G|rcsb pdb:4Z4H|rcsb pdb:4Z4I|rcsb pdb:5JS1|rcsb pdb:3QX9|rcsb pdb:5JS2|rcsb pdb:5KI6|ensembl:ENSG00000123908(gene)|ensembl:ENST00000220592(transcript)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000932"(P-body)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006412"(translation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0030425"(dendrite)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0035087"(siRNA loading onto RISC involved in RNA interference)|go:"GO:0035194"(post-transcriptional gene silencing by RNA)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0035279"(miRNA-mediated gene silencing by mRNA destabilization)|go:"GO:0035280"(miRNA loading onto RISC)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042985"(negative regulation of amyloid precursor protein biosynthetic process)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0045975"(positive regulation of translation, ncRNA-mediated)|go:"GO:0046872"(metal ion binding)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0070551"(endoribonuclease activity, cleaving siRNA-paired mRNA)|go:"GO:0070578"(RISC-loading complex)|go:"GO:0090624"(endoribonuclease activity, cleaving miRNA-paired mRNA)|go:"GO:0090625"(mRNA destabilization-mediated gene silencing by siRNA)|go:"GO:0098808"(mRNA cap binding)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1901165"(positive regulation of trophoblast cell migration)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR028602|interpro:IPR032472|interpro:IPR032473|interpro:IPR032474|interpro:IPR036085|interpro:IPR036397|mint:Q9UKV8|rcsb pdb:3LUC|rcsb pdb:3LUD|rcsb pdb:3LUG|rcsb pdb:3LUH|rcsb pdb:3LUJ|rcsb pdb:3LUK|rcsb pdb:3QX8|dip:DIP-29194N - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:svQfKWBCSAPSGFAV5YPZXFvcqkk9606 rogid:8GU8wsz9kTG2ViT7pP7uQyYTVsc9606 rigid:7fqj2Gju3X4HbV0gQNAzWx9cUhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6B0I6 uniprotkb:Q14011 intact:EBI-4311651|uniprotkb:Q9NW76|uniprotkb:B3KPC4|uniprotkb:Q9NT41|uniprotkb:Q0VF39|ensembl:ENSP00000334181|ensembl:ENSP00000460897|ensembl:ENSP00000482224 intact:EBI-538850|uniprotkb:B4E2X2|intact:EBI-10980353|uniprotkb:B3KT17|ensembl:ENSP00000322887|ensembl:ENSP00000465779|ensembl:ENSP00000466110|ensembl:ENSP00000466207|ensembl:ENSP00000468788 psi-mi:kdm4d_human(display_long)|uniprotkb:KDM4D(gene name)|psi-mi:KDM4D(display_short)|uniprotkb:JHDM3D(gene name synonym)|uniprotkb:JMJD2D(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3D(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2D(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4D"(gene name synonym) psi-mi:cirbp_human(display_long)|uniprotkb:Glycine-rich RNA-binding protein CIRP(gene name synonym)|uniprotkb:A18 hnRNP(gene name synonym)|uniprotkb:CIRBP(gene name)|psi-mi:CIRBP(display_short)|uniprotkb:A18HNRNP(gene name synonym)|uniprotkb:CIRP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480104|imex:IM-26985-481 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060509.2|rcsb pdb:5PI6|rcsb pdb:5PI7|rcsb pdb:5PI8|rcsb pdb:5PI9|rcsb pdb:5PIA|rcsb pdb:5PIB|rcsb pdb:5PIC|rcsb pdb:5PID|rcsb pdb:5PIE|rcsb pdb:5PIF|rcsb pdb:5PIG|rcsb pdb:5PIH|rcsb pdb:5PII|rcsb pdb:5PIJ|rcsb pdb:5PIK|rcsb pdb:5PIL|rcsb pdb:5PIM|rcsb pdb:5PIN|rcsb pdb:5PIO|rcsb pdb:5PIP|rcsb pdb:5PIQ|rcsb pdb:5PIR|rcsb pdb:5PIS|rcsb pdb:5PIT|rcsb pdb:5PIU|rcsb pdb:5PIV|rcsb pdb:5PIW|rcsb pdb:5PIX|rcsb pdb:5PIY|rcsb pdb:5PIZ|rcsb pdb:5PJ0|rcsb pdb:5PI5|rcsb pdb:5PJ1|rcsb pdb:5PJ2|rcsb pdb:5PJ3|rcsb pdb:5PJ4|rcsb pdb:5PJ6|rcsb pdb:5PJ7|rcsb pdb:5PJ8|rcsb pdb:5PJ9|rcsb pdb:5PJA|rcsb pdb:5PJB|rcsb pdb:5PJC|rcsb pdb:5PJD|rcsb pdb:5PJE|rcsb pdb:5PJF|rcsb pdb:5PJG|rcsb pdb:5PJ5|rcsb pdb:5PJH|rcsb pdb:5PJI|rcsb pdb:5PJJ|rcsb pdb:5PJK|rcsb pdb:5PJL|rcsb pdb:5PJM|rcsb pdb:5PJN|rcsb pdb:5PJO|rcsb pdb:5PJP|rcsb pdb:5PJQ|rcsb pdb:5PJR|rcsb pdb:5PJS|rcsb pdb:6ETT|rcsb pdb:6ETU|rcsb pdb:5PJT|rcsb pdb:6ETV|rcsb pdb:6ETW|rcsb pdb:6F5Q|rcsb pdb:6F5R|rcsb pdb:6F5S|rcsb pdb:6F5T|rcsb pdb:6H0W|rcsb pdb:6H0X|rcsb pdb:6H0Y|rcsb pdb:6H0Z|rcsb pdb:6H10|rcsb pdb:6H11|reactome:R-HSA-3214842|ensembl:ENSG00000186280(gene)|ensembl:ENST00000335080(transcript)|ensembl:ENST00000536741(transcript)|ensembl:ENST00000610872(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|rcsb pdb:5PJV|rcsb pdb:5PJW|rcsb pdb:5PJX|rcsb pdb:5PJY|rcsb pdb:5PJZ|rcsb pdb:5PK0|rcsb pdb:5PK1|rcsb pdb:5PK2|rcsb pdb:5PJU|rcsb pdb:5PK3|rcsb pdb:5PK4|rcsb pdb:5PK5|rcsb pdb:5PK6|rcsb pdb:5PK7|rcsb pdb:5PK8|rcsb pdb:5PK9|rcsb pdb:5PKA|rcsb pdb:5PKB|rcsb pdb:5PKC|rcsb pdb:5PKD|rcsb pdb:5PKE|rcsb pdb:5PKF|rcsb pdb:5PKG|rcsb pdb:5PKH|rcsb pdb:5PKI|rcsb pdb:5PKJ|rcsb pdb:5PKK|rcsb pdb:5PKL|rcsb pdb:5PKM|rcsb pdb:5PKN|rcsb pdb:5PKO|rcsb pdb:5PKP|rcsb pdb:5PKQ|rcsb pdb:5PKR|rcsb pdb:5PKS|rcsb pdb:5PKT|rcsb pdb:5PKU|rcsb pdb:5PKV|rcsb pdb:5PKW|rcsb pdb:5PKX|rcsb pdb:5PKY|rcsb pdb:5PKZ|rcsb pdb:5PL0|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072562"(blood microparticle)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|mint:Q6B0I6|rcsb pdb:3DXT|rcsb pdb:3DXU|rcsb pdb:4D6Q|rcsb pdb:4D6R|rcsb pdb:4D6S|rcsb pdb:4HON|rcsb pdb:5PL2|rcsb pdb:5PL3|rcsb pdb:5PL1|rcsb pdb:5PL4|rcsb pdb:5PL5|rcsb pdb:5PL6|rcsb pdb:5PL7|rcsb pdb:5PL8|rcsb pdb:5PL9|rcsb pdb:5PLA|rcsb pdb:5PLB|rcsb pdb:5PLC|rcsb pdb:5PLD|rcsb pdb:5PLE|rcsb pdb:5PLF|rcsb pdb:5PLG|rcsb pdb:5PLH|rcsb pdb:5PLI|rcsb pdb:5PLJ|rcsb pdb:5PLK|rcsb pdb:5PLL|rcsb pdb:5PLM|rcsb pdb:5PLN|rcsb pdb:5PLO|rcsb pdb:5PLP|rcsb pdb:5PLQ|rcsb pdb:5PLR|rcsb pdb:5PLS|rcsb pdb:5F5A|rcsb pdb:5F5C|rcsb pdb:5FP4|rcsb pdb:5FP7|rcsb pdb:5FP8|rcsb pdb:5FP9|rcsb pdb:5FPA|rcsb pdb:5FPB|rcsb pdb:5PH0|rcsb pdb:5PH1|rcsb pdb:5PH2|rcsb pdb:5PH3|rcsb pdb:5PH4|rcsb pdb:4HOO|rcsb pdb:5PH5|rcsb pdb:5PH6|rcsb pdb:5PH7|rcsb pdb:5PH8|rcsb pdb:5PH9|rcsb pdb:5PHA|rcsb pdb:5PHB|rcsb pdb:5PHC|rcsb pdb:5PHD|rcsb pdb:5PHE|rcsb pdb:5PLU|rcsb pdb:5PLV|rcsb pdb:5PLW|rcsb pdb:5PLX|rcsb pdb:5PLY|rcsb pdb:5PLZ|rcsb pdb:5PM0|rcsb pdb:5PM1|rcsb pdb:5PM2|rcsb pdb:5PM3|rcsb pdb:5PM4|rcsb pdb:5PM5|rcsb pdb:5PM6|rcsb pdb:5PM7|rcsb pdb:5PM8|rcsb pdb:5PM9|rcsb pdb:5PMA|rcsb pdb:5PMB|rcsb pdb:5PMC|rcsb pdb:5PMD|rcsb pdb:5PME|rcsb pdb:5PMF|rcsb pdb:5PMG|rcsb pdb:5PMH|rcsb pdb:5PMI|rcsb pdb:5PMJ|rcsb pdb:5PMK|rcsb pdb:5PML|rcsb pdb:5PMM|rcsb pdb:5PMN|rcsb pdb:5PMO|rcsb pdb:5PMP|rcsb pdb:5PMQ|rcsb pdb:5PMR|rcsb pdb:5PMS|rcsb pdb:5PMT|rcsb pdb:5PMU|rcsb pdb:5PMV|rcsb pdb:5PMW|rcsb pdb:5PMX|rcsb pdb:5PMY|rcsb pdb:5PMZ|rcsb pdb:5PN0|rcsb pdb:5PN1|rcsb pdb:5PN2|rcsb pdb:5PN3|rcsb pdb:5PN4|rcsb pdb:5PN5|rcsb pdb:5PN6|rcsb pdb:5PN7|rcsb pdb:5PN8|rcsb pdb:5PN9|rcsb pdb:5PNA|rcsb pdb:5PNB|rcsb pdb:5PNC|rcsb pdb:5PND|rcsb pdb:5PNE|rcsb pdb:5PNF|rcsb pdb:5PNG|rcsb pdb:5PNH|rcsb pdb:5PNI|rcsb pdb:5PNJ|rcsb pdb:5PNK|rcsb pdb:5PNL|rcsb pdb:5PNM|rcsb pdb:5PLT|rcsb pdb:5PNN|rcsb pdb:5PNO|rcsb pdb:5PNP|rcsb pdb:5PNQ|rcsb pdb:5PNR|rcsb pdb:5PNS|rcsb pdb:5PNU|rcsb pdb:5PNV|rcsb pdb:5PNW|rcsb pdb:6ETE|rcsb pdb:6ETG|rcsb pdb:6ETS|rcsb pdb:5PHJ|rcsb pdb:5PHK|rcsb pdb:5PHL|rcsb pdb:5PHM|rcsb pdb:5PHN|rcsb pdb:5PHO|rcsb pdb:5PHP|rcsb pdb:5PHQ|rcsb pdb:5PHR|rcsb pdb:5PHS|rcsb pdb:5PHT|rcsb pdb:5PHU|rcsb pdb:5PHV|rcsb pdb:5PHF|rcsb pdb:5PHG|rcsb pdb:5PHH|rcsb pdb:5PHI|rcsb pdb:5PHW|rcsb pdb:5PHX|rcsb pdb:5PHY|rcsb pdb:5PHZ|rcsb pdb:5PI0|rcsb pdb:5PI1|rcsb pdb:5PI2|rcsb pdb:5PI3|rcsb pdb:5PI4|dip:DIP-29606N refseq:NP_001271.1|refseq:XP_006722700.1|refseq:NP_001287744.1|refseq:NP_001287758.1|ensembl:ENSG00000099622(gene)|ensembl:ENST00000320936(transcript)|ensembl:ENST00000585630(transcript)|ensembl:ENST00000586472(transcript)|ensembl:ENST00000588030(transcript)|ensembl:ENST00000588090(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0009409"(response to cold)|go:"GO:0009411"(response to UV)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030371"(translation repressor activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034278|interpro:IPR035979|mint:Q14011|rcsb pdb:1X5S|rcsb pdb:5TBX - - comment:"author score: 28" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:svQfKWBCSAPSGFAV5YPZXFvcqkk9606 rogid:nm6/8k5Pw1AnoXsSw9cazJkL49U9606 rigid:7fqj2Gju3X4HbV0gQNAzWx9cUhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6B0I6 uniprotkb:Q9NQ92 intact:EBI-4311651|uniprotkb:Q9NW76|uniprotkb:B3KPC4|uniprotkb:Q9NT41|uniprotkb:Q0VF39|ensembl:ENSP00000334181|ensembl:ENSP00000460897|ensembl:ENSP00000482224 intact:EBI-1642558|uniprotkb:E1P656|uniprotkb:A6NP14|uniprotkb:Q96EF5|uniprotkb:Q96P75|ensembl:ENSP00000304327 psi-mi:kdm4d_human(display_long)|uniprotkb:KDM4D(gene name)|psi-mi:KDM4D(display_short)|uniprotkb:JHDM3D(gene name synonym)|uniprotkb:JMJD2D(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3D(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2D(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4D"(gene name synonym) psi-mi:coprs_human(display_long)|uniprotkb:COPRS(gene name)|psi-mi:COPRS(display_short)|uniprotkb:C17orf79(gene name synonym)|uniprotkb:COPR5(gene name synonym)|uniprotkb:Cooperator of PRMT5(gene name synonym)|uniprotkb:Protein TTP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480104|imex:IM-26985-481 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060509.2|rcsb pdb:5PI6|rcsb pdb:5PI7|rcsb pdb:5PI8|rcsb pdb:5PI9|rcsb pdb:5PIA|rcsb pdb:5PIB|rcsb pdb:5PIC|rcsb pdb:5PID|rcsb pdb:5PIE|rcsb pdb:5PIF|rcsb pdb:5PIG|rcsb pdb:5PIH|rcsb pdb:5PII|rcsb pdb:5PIJ|rcsb pdb:5PIK|rcsb pdb:5PIL|rcsb pdb:5PIM|rcsb pdb:5PIN|rcsb pdb:5PIO|rcsb pdb:5PIP|rcsb pdb:5PIQ|rcsb pdb:5PIR|rcsb pdb:5PIS|rcsb pdb:5PIT|rcsb pdb:5PIU|rcsb pdb:5PIV|rcsb pdb:5PIW|rcsb pdb:5PIX|rcsb pdb:5PIY|rcsb pdb:5PIZ|rcsb pdb:5PJ0|rcsb pdb:5PI5|rcsb pdb:5PJ1|rcsb pdb:5PJ2|rcsb pdb:5PJ3|rcsb pdb:5PJ4|rcsb pdb:5PJ6|rcsb pdb:5PJ7|rcsb pdb:5PJ8|rcsb pdb:5PJ9|rcsb pdb:5PJA|rcsb pdb:5PJB|rcsb pdb:5PJC|rcsb pdb:5PJD|rcsb pdb:5PJE|rcsb pdb:5PJF|rcsb pdb:5PJG|rcsb pdb:5PJ5|rcsb pdb:5PJH|rcsb pdb:5PJI|rcsb pdb:5PJJ|rcsb pdb:5PJK|rcsb pdb:5PJL|rcsb pdb:5PJM|rcsb pdb:5PJN|rcsb pdb:5PJO|rcsb pdb:5PJP|rcsb pdb:5PJQ|rcsb pdb:5PJR|rcsb pdb:5PJS|rcsb pdb:6ETT|rcsb pdb:6ETU|rcsb pdb:5PJT|rcsb pdb:6ETV|rcsb pdb:6ETW|rcsb pdb:6F5Q|rcsb pdb:6F5R|rcsb pdb:6F5S|rcsb pdb:6F5T|rcsb pdb:6H0W|rcsb pdb:6H0X|rcsb pdb:6H0Y|rcsb pdb:6H0Z|rcsb pdb:6H10|rcsb pdb:6H11|reactome:R-HSA-3214842|ensembl:ENSG00000186280(gene)|ensembl:ENST00000335080(transcript)|ensembl:ENST00000536741(transcript)|ensembl:ENST00000610872(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|rcsb pdb:5PJV|rcsb pdb:5PJW|rcsb pdb:5PJX|rcsb pdb:5PJY|rcsb pdb:5PJZ|rcsb pdb:5PK0|rcsb pdb:5PK1|rcsb pdb:5PK2|rcsb pdb:5PJU|rcsb pdb:5PK3|rcsb pdb:5PK4|rcsb pdb:5PK5|rcsb pdb:5PK6|rcsb pdb:5PK7|rcsb pdb:5PK8|rcsb pdb:5PK9|rcsb pdb:5PKA|rcsb pdb:5PKB|rcsb pdb:5PKC|rcsb pdb:5PKD|rcsb pdb:5PKE|rcsb pdb:5PKF|rcsb pdb:5PKG|rcsb pdb:5PKH|rcsb pdb:5PKI|rcsb pdb:5PKJ|rcsb pdb:5PKK|rcsb pdb:5PKL|rcsb pdb:5PKM|rcsb pdb:5PKN|rcsb pdb:5PKO|rcsb pdb:5PKP|rcsb pdb:5PKQ|rcsb pdb:5PKR|rcsb pdb:5PKS|rcsb pdb:5PKT|rcsb pdb:5PKU|rcsb pdb:5PKV|rcsb pdb:5PKW|rcsb pdb:5PKX|rcsb pdb:5PKY|rcsb pdb:5PKZ|rcsb pdb:5PL0|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072562"(blood microparticle)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|mint:Q6B0I6|rcsb pdb:3DXT|rcsb pdb:3DXU|rcsb pdb:4D6Q|rcsb pdb:4D6R|rcsb pdb:4D6S|rcsb pdb:4HON|rcsb pdb:5PL2|rcsb pdb:5PL3|rcsb pdb:5PL1|rcsb pdb:5PL4|rcsb pdb:5PL5|rcsb pdb:5PL6|rcsb pdb:5PL7|rcsb pdb:5PL8|rcsb pdb:5PL9|rcsb pdb:5PLA|rcsb pdb:5PLB|rcsb pdb:5PLC|rcsb pdb:5PLD|rcsb pdb:5PLE|rcsb pdb:5PLF|rcsb pdb:5PLG|rcsb pdb:5PLH|rcsb pdb:5PLI|rcsb pdb:5PLJ|rcsb pdb:5PLK|rcsb pdb:5PLL|rcsb pdb:5PLM|rcsb pdb:5PLN|rcsb pdb:5PLO|rcsb pdb:5PLP|rcsb pdb:5PLQ|rcsb pdb:5PLR|rcsb pdb:5PLS|rcsb pdb:5F5A|rcsb pdb:5F5C|rcsb pdb:5FP4|rcsb pdb:5FP7|rcsb pdb:5FP8|rcsb pdb:5FP9|rcsb pdb:5FPA|rcsb pdb:5FPB|rcsb pdb:5PH0|rcsb pdb:5PH1|rcsb pdb:5PH2|rcsb pdb:5PH3|rcsb pdb:5PH4|rcsb pdb:4HOO|rcsb pdb:5PH5|rcsb pdb:5PH6|rcsb pdb:5PH7|rcsb pdb:5PH8|rcsb pdb:5PH9|rcsb pdb:5PHA|rcsb pdb:5PHB|rcsb pdb:5PHC|rcsb pdb:5PHD|rcsb pdb:5PHE|rcsb pdb:5PLU|rcsb pdb:5PLV|rcsb pdb:5PLW|rcsb pdb:5PLX|rcsb pdb:5PLY|rcsb pdb:5PLZ|rcsb pdb:5PM0|rcsb pdb:5PM1|rcsb pdb:5PM2|rcsb pdb:5PM3|rcsb pdb:5PM4|rcsb pdb:5PM5|rcsb pdb:5PM6|rcsb pdb:5PM7|rcsb pdb:5PM8|rcsb pdb:5PM9|rcsb pdb:5PMA|rcsb pdb:5PMB|rcsb pdb:5PMC|rcsb pdb:5PMD|rcsb pdb:5PME|rcsb pdb:5PMF|rcsb pdb:5PMG|rcsb pdb:5PMH|rcsb pdb:5PMI|rcsb pdb:5PMJ|rcsb pdb:5PMK|rcsb pdb:5PML|rcsb pdb:5PMM|rcsb pdb:5PMN|rcsb pdb:5PMO|rcsb pdb:5PMP|rcsb pdb:5PMQ|rcsb pdb:5PMR|rcsb pdb:5PMS|rcsb pdb:5PMT|rcsb pdb:5PMU|rcsb pdb:5PMV|rcsb pdb:5PMW|rcsb pdb:5PMX|rcsb pdb:5PMY|rcsb pdb:5PMZ|rcsb pdb:5PN0|rcsb pdb:5PN1|rcsb pdb:5PN2|rcsb pdb:5PN3|rcsb pdb:5PN4|rcsb pdb:5PN5|rcsb pdb:5PN6|rcsb pdb:5PN7|rcsb pdb:5PN8|rcsb pdb:5PN9|rcsb pdb:5PNA|rcsb pdb:5PNB|rcsb pdb:5PNC|rcsb pdb:5PND|rcsb pdb:5PNE|rcsb pdb:5PNF|rcsb pdb:5PNG|rcsb pdb:5PNH|rcsb pdb:5PNI|rcsb pdb:5PNJ|rcsb pdb:5PNK|rcsb pdb:5PNL|rcsb pdb:5PNM|rcsb pdb:5PLT|rcsb pdb:5PNN|rcsb pdb:5PNO|rcsb pdb:5PNP|rcsb pdb:5PNQ|rcsb pdb:5PNR|rcsb pdb:5PNS|rcsb pdb:5PNU|rcsb pdb:5PNV|rcsb pdb:5PNW|rcsb pdb:6ETE|rcsb pdb:6ETG|rcsb pdb:6ETS|rcsb pdb:5PHJ|rcsb pdb:5PHK|rcsb pdb:5PHL|rcsb pdb:5PHM|rcsb pdb:5PHN|rcsb pdb:5PHO|rcsb pdb:5PHP|rcsb pdb:5PHQ|rcsb pdb:5PHR|rcsb pdb:5PHS|rcsb pdb:5PHT|rcsb pdb:5PHU|rcsb pdb:5PHV|rcsb pdb:5PHF|rcsb pdb:5PHG|rcsb pdb:5PHH|rcsb pdb:5PHI|rcsb pdb:5PHW|rcsb pdb:5PHX|rcsb pdb:5PHY|rcsb pdb:5PHZ|rcsb pdb:5PI0|rcsb pdb:5PI1|rcsb pdb:5PI2|rcsb pdb:5PI3|rcsb pdb:5PI4|dip:DIP-29606N refseq:NP_060875.2|ensembl:ENSG00000172301(gene)|ensembl:ENST00000302362(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0042393"(histone binding)|go:"GO:0043985"(histone H4-R3 methylation)|interpro:IPR029289|mint:Q9NQ92|reactome:R-HSA-3214858 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:svQfKWBCSAPSGFAV5YPZXFvcqkk9606 rogid:qO6jrJ2Zx0gVwqXbB+1EtiYvb589606 rigid:7fqj2Gju3X4HbV0gQNAzWx9cUhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6B0I6 uniprotkb:P52756 intact:EBI-4311651|uniprotkb:Q9NW76|uniprotkb:B3KPC4|uniprotkb:Q9NT41|uniprotkb:Q0VF39|ensembl:ENSP00000334181|ensembl:ENSP00000460897|ensembl:ENSP00000482224 intact:EBI-714003|uniprotkb:Q93021|uniprotkb:Q9BU14|uniprotkb:Q9UKY8|uniprotkb:Q9UL24|ensembl:ENSP00000343054|uniprotkb:B2RA45|uniprotkb:B4DM16|uniprotkb:B4DMF9|uniprotkb:B4DZ63|uniprotkb:Q9HDA6|intact:EBI-16431417 psi-mi:kdm4d_human(display_long)|uniprotkb:KDM4D(gene name)|psi-mi:KDM4D(display_short)|uniprotkb:JHDM3D(gene name synonym)|uniprotkb:JMJD2D(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3D(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2D(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4D"(gene name synonym) psi-mi:rbm5_human(display_long)|uniprotkb:RNA-binding motif protein 5(gene name synonym)|uniprotkb:Putative tumor suppressor LUCA15(gene name synonym)|uniprotkb:Protein G15(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-9(gene name synonym)|uniprotkb:RBM5(gene name)|psi-mi:RBM5(display_short)|uniprotkb:H37(orf name)|uniprotkb:LUCA15(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480104|imex:IM-26985-481 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060509.2|rcsb pdb:5PI6|rcsb pdb:5PI7|rcsb pdb:5PI8|rcsb pdb:5PI9|rcsb pdb:5PIA|rcsb pdb:5PIB|rcsb pdb:5PIC|rcsb pdb:5PID|rcsb pdb:5PIE|rcsb pdb:5PIF|rcsb pdb:5PIG|rcsb pdb:5PIH|rcsb pdb:5PII|rcsb pdb:5PIJ|rcsb pdb:5PIK|rcsb pdb:5PIL|rcsb pdb:5PIM|rcsb pdb:5PIN|rcsb pdb:5PIO|rcsb pdb:5PIP|rcsb pdb:5PIQ|rcsb pdb:5PIR|rcsb pdb:5PIS|rcsb pdb:5PIT|rcsb pdb:5PIU|rcsb pdb:5PIV|rcsb pdb:5PIW|rcsb pdb:5PIX|rcsb pdb:5PIY|rcsb pdb:5PIZ|rcsb pdb:5PJ0|rcsb pdb:5PI5|rcsb pdb:5PJ1|rcsb pdb:5PJ2|rcsb pdb:5PJ3|rcsb pdb:5PJ4|rcsb pdb:5PJ6|rcsb pdb:5PJ7|rcsb pdb:5PJ8|rcsb pdb:5PJ9|rcsb pdb:5PJA|rcsb pdb:5PJB|rcsb pdb:5PJC|rcsb pdb:5PJD|rcsb pdb:5PJE|rcsb pdb:5PJF|rcsb pdb:5PJG|rcsb pdb:5PJ5|rcsb pdb:5PJH|rcsb pdb:5PJI|rcsb pdb:5PJJ|rcsb pdb:5PJK|rcsb pdb:5PJL|rcsb pdb:5PJM|rcsb pdb:5PJN|rcsb pdb:5PJO|rcsb pdb:5PJP|rcsb pdb:5PJQ|rcsb pdb:5PJR|rcsb pdb:5PJS|rcsb pdb:6ETT|rcsb pdb:6ETU|rcsb pdb:5PJT|rcsb pdb:6ETV|rcsb pdb:6ETW|rcsb pdb:6F5Q|rcsb pdb:6F5R|rcsb pdb:6F5S|rcsb pdb:6F5T|rcsb pdb:6H0W|rcsb pdb:6H0X|rcsb pdb:6H0Y|rcsb pdb:6H0Z|rcsb pdb:6H10|rcsb pdb:6H11|reactome:R-HSA-3214842|ensembl:ENSG00000186280(gene)|ensembl:ENST00000335080(transcript)|ensembl:ENST00000536741(transcript)|ensembl:ENST00000610872(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|rcsb pdb:5PJV|rcsb pdb:5PJW|rcsb pdb:5PJX|rcsb pdb:5PJY|rcsb pdb:5PJZ|rcsb pdb:5PK0|rcsb pdb:5PK1|rcsb pdb:5PK2|rcsb pdb:5PJU|rcsb pdb:5PK3|rcsb pdb:5PK4|rcsb pdb:5PK5|rcsb pdb:5PK6|rcsb pdb:5PK7|rcsb pdb:5PK8|rcsb pdb:5PK9|rcsb pdb:5PKA|rcsb pdb:5PKB|rcsb pdb:5PKC|rcsb pdb:5PKD|rcsb pdb:5PKE|rcsb pdb:5PKF|rcsb pdb:5PKG|rcsb pdb:5PKH|rcsb pdb:5PKI|rcsb pdb:5PKJ|rcsb pdb:5PKK|rcsb pdb:5PKL|rcsb pdb:5PKM|rcsb pdb:5PKN|rcsb pdb:5PKO|rcsb pdb:5PKP|rcsb pdb:5PKQ|rcsb pdb:5PKR|rcsb pdb:5PKS|rcsb pdb:5PKT|rcsb pdb:5PKU|rcsb pdb:5PKV|rcsb pdb:5PKW|rcsb pdb:5PKX|rcsb pdb:5PKY|rcsb pdb:5PKZ|rcsb pdb:5PL0|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072562"(blood microparticle)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|mint:Q6B0I6|rcsb pdb:3DXT|rcsb pdb:3DXU|rcsb pdb:4D6Q|rcsb pdb:4D6R|rcsb pdb:4D6S|rcsb pdb:4HON|rcsb pdb:5PL2|rcsb pdb:5PL3|rcsb pdb:5PL1|rcsb pdb:5PL4|rcsb pdb:5PL5|rcsb pdb:5PL6|rcsb pdb:5PL7|rcsb pdb:5PL8|rcsb pdb:5PL9|rcsb pdb:5PLA|rcsb pdb:5PLB|rcsb pdb:5PLC|rcsb pdb:5PLD|rcsb pdb:5PLE|rcsb pdb:5PLF|rcsb pdb:5PLG|rcsb pdb:5PLH|rcsb pdb:5PLI|rcsb pdb:5PLJ|rcsb pdb:5PLK|rcsb pdb:5PLL|rcsb pdb:5PLM|rcsb pdb:5PLN|rcsb pdb:5PLO|rcsb pdb:5PLP|rcsb pdb:5PLQ|rcsb pdb:5PLR|rcsb pdb:5PLS|rcsb pdb:5F5A|rcsb pdb:5F5C|rcsb pdb:5FP4|rcsb pdb:5FP7|rcsb pdb:5FP8|rcsb pdb:5FP9|rcsb pdb:5FPA|rcsb pdb:5FPB|rcsb pdb:5PH0|rcsb pdb:5PH1|rcsb pdb:5PH2|rcsb pdb:5PH3|rcsb pdb:5PH4|rcsb pdb:4HOO|rcsb pdb:5PH5|rcsb pdb:5PH6|rcsb pdb:5PH7|rcsb pdb:5PH8|rcsb pdb:5PH9|rcsb pdb:5PHA|rcsb pdb:5PHB|rcsb pdb:5PHC|rcsb pdb:5PHD|rcsb pdb:5PHE|rcsb pdb:5PLU|rcsb pdb:5PLV|rcsb pdb:5PLW|rcsb pdb:5PLX|rcsb pdb:5PLY|rcsb pdb:5PLZ|rcsb pdb:5PM0|rcsb pdb:5PM1|rcsb pdb:5PM2|rcsb pdb:5PM3|rcsb pdb:5PM4|rcsb pdb:5PM5|rcsb pdb:5PM6|rcsb pdb:5PM7|rcsb pdb:5PM8|rcsb pdb:5PM9|rcsb pdb:5PMA|rcsb pdb:5PMB|rcsb pdb:5PMC|rcsb pdb:5PMD|rcsb pdb:5PME|rcsb pdb:5PMF|rcsb pdb:5PMG|rcsb pdb:5PMH|rcsb pdb:5PMI|rcsb pdb:5PMJ|rcsb pdb:5PMK|rcsb pdb:5PML|rcsb pdb:5PMM|rcsb pdb:5PMN|rcsb pdb:5PMO|rcsb pdb:5PMP|rcsb pdb:5PMQ|rcsb pdb:5PMR|rcsb pdb:5PMS|rcsb pdb:5PMT|rcsb pdb:5PMU|rcsb pdb:5PMV|rcsb pdb:5PMW|rcsb pdb:5PMX|rcsb pdb:5PMY|rcsb pdb:5PMZ|rcsb pdb:5PN0|rcsb pdb:5PN1|rcsb pdb:5PN2|rcsb pdb:5PN3|rcsb pdb:5PN4|rcsb pdb:5PN5|rcsb pdb:5PN6|rcsb pdb:5PN7|rcsb pdb:5PN8|rcsb pdb:5PN9|rcsb pdb:5PNA|rcsb pdb:5PNB|rcsb pdb:5PNC|rcsb pdb:5PND|rcsb pdb:5PNE|rcsb pdb:5PNF|rcsb pdb:5PNG|rcsb pdb:5PNH|rcsb pdb:5PNI|rcsb pdb:5PNJ|rcsb pdb:5PNK|rcsb pdb:5PNL|rcsb pdb:5PNM|rcsb pdb:5PLT|rcsb pdb:5PNN|rcsb pdb:5PNO|rcsb pdb:5PNP|rcsb pdb:5PNQ|rcsb pdb:5PNR|rcsb pdb:5PNS|rcsb pdb:5PNU|rcsb pdb:5PNV|rcsb pdb:5PNW|rcsb pdb:6ETE|rcsb pdb:6ETG|rcsb pdb:6ETS|rcsb pdb:5PHJ|rcsb pdb:5PHK|rcsb pdb:5PHL|rcsb pdb:5PHM|rcsb pdb:5PHN|rcsb pdb:5PHO|rcsb pdb:5PHP|rcsb pdb:5PHQ|rcsb pdb:5PHR|rcsb pdb:5PHS|rcsb pdb:5PHT|rcsb pdb:5PHU|rcsb pdb:5PHV|rcsb pdb:5PHF|rcsb pdb:5PHG|rcsb pdb:5PHH|rcsb pdb:5PHI|rcsb pdb:5PHW|rcsb pdb:5PHX|rcsb pdb:5PHY|rcsb pdb:5PHZ|rcsb pdb:5PI0|rcsb pdb:5PI1|rcsb pdb:5PI2|rcsb pdb:5PI3|rcsb pdb:5PI4|dip:DIP-29606N ensembl:ENSG00000003756(gene)|ensembl:ENST00000347869(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR033094|interpro:IPR034991|interpro:IPR034993|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0006396"(RNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000467(D111/G-patch)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036443|interpro:IPR041591|mint:P52756|rcsb pdb:2LK0|rcsb pdb:2LK1|rcsb pdb:2LKZ|rcsb pdb:5MF9|rcsb pdb:5MFY|reactome:R-HSA-72163|refseq:NP_005769.1|refseq:XP_016860992.1|dip:DIP-47277N - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:svQfKWBCSAPSGFAV5YPZXFvcqkk9606 rogid:LsPTpaKrGY2xtpYofHbFVXjSi/A9606 rigid:7fqj2Gju3X4HbV0gQNAzWx9cUhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6B0I6 uniprotkb:P49773 intact:EBI-4311651|uniprotkb:Q9NW76|uniprotkb:B3KPC4|uniprotkb:Q9NT41|uniprotkb:Q0VF39|ensembl:ENSP00000334181|ensembl:ENSP00000460897|ensembl:ENSP00000482224 intact:EBI-1054330|uniprotkb:Q9H5W8|ensembl:ENSP00000304229 psi-mi:kdm4d_human(display_long)|uniprotkb:KDM4D(gene name)|psi-mi:KDM4D(display_short)|uniprotkb:JHDM3D(gene name synonym)|uniprotkb:JMJD2D(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3D(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2D(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4D"(gene name synonym) psi-mi:hint1_human(display_long)|uniprotkb:Protein kinase C inhibitor 1(gene name synonym)|uniprotkb:Protein kinase C-interacting protein 1(gene name synonym)|uniprotkb:HINT1(gene name)|psi-mi:HINT1(display_short)|uniprotkb:HINT(gene name synonym)|uniprotkb:PKCI1(gene name synonym)|uniprotkb:PRKCNH1(gene name synonym)|uniprotkb:Desumoylating isopeptidase HINT1(gene name synonym)|uniprotkb:Histidine triad nucleotide-binding protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480104|imex:IM-26985-481 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060509.2|rcsb pdb:5PI6|rcsb pdb:5PI7|rcsb pdb:5PI8|rcsb pdb:5PI9|rcsb pdb:5PIA|rcsb pdb:5PIB|rcsb pdb:5PIC|rcsb pdb:5PID|rcsb pdb:5PIE|rcsb pdb:5PIF|rcsb pdb:5PIG|rcsb pdb:5PIH|rcsb pdb:5PII|rcsb pdb:5PIJ|rcsb pdb:5PIK|rcsb pdb:5PIL|rcsb pdb:5PIM|rcsb pdb:5PIN|rcsb pdb:5PIO|rcsb pdb:5PIP|rcsb pdb:5PIQ|rcsb pdb:5PIR|rcsb pdb:5PIS|rcsb pdb:5PIT|rcsb pdb:5PIU|rcsb pdb:5PIV|rcsb pdb:5PIW|rcsb pdb:5PIX|rcsb pdb:5PIY|rcsb pdb:5PIZ|rcsb pdb:5PJ0|rcsb pdb:5PI5|rcsb pdb:5PJ1|rcsb pdb:5PJ2|rcsb pdb:5PJ3|rcsb pdb:5PJ4|rcsb pdb:5PJ6|rcsb pdb:5PJ7|rcsb pdb:5PJ8|rcsb pdb:5PJ9|rcsb pdb:5PJA|rcsb pdb:5PJB|rcsb pdb:5PJC|rcsb pdb:5PJD|rcsb pdb:5PJE|rcsb pdb:5PJF|rcsb pdb:5PJG|rcsb pdb:5PJ5|rcsb pdb:5PJH|rcsb pdb:5PJI|rcsb pdb:5PJJ|rcsb pdb:5PJK|rcsb pdb:5PJL|rcsb pdb:5PJM|rcsb pdb:5PJN|rcsb pdb:5PJO|rcsb pdb:5PJP|rcsb pdb:5PJQ|rcsb pdb:5PJR|rcsb pdb:5PJS|rcsb pdb:6ETT|rcsb pdb:6ETU|rcsb pdb:5PJT|rcsb pdb:6ETV|rcsb pdb:6ETW|rcsb pdb:6F5Q|rcsb pdb:6F5R|rcsb pdb:6F5S|rcsb pdb:6F5T|rcsb pdb:6H0W|rcsb pdb:6H0X|rcsb pdb:6H0Y|rcsb pdb:6H0Z|rcsb pdb:6H10|rcsb pdb:6H11|reactome:R-HSA-3214842|ensembl:ENSG00000186280(gene)|ensembl:ENST00000335080(transcript)|ensembl:ENST00000536741(transcript)|ensembl:ENST00000610872(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|rcsb pdb:5PJV|rcsb pdb:5PJW|rcsb pdb:5PJX|rcsb pdb:5PJY|rcsb pdb:5PJZ|rcsb pdb:5PK0|rcsb pdb:5PK1|rcsb pdb:5PK2|rcsb pdb:5PJU|rcsb pdb:5PK3|rcsb pdb:5PK4|rcsb pdb:5PK5|rcsb pdb:5PK6|rcsb pdb:5PK7|rcsb pdb:5PK8|rcsb pdb:5PK9|rcsb pdb:5PKA|rcsb pdb:5PKB|rcsb pdb:5PKC|rcsb pdb:5PKD|rcsb pdb:5PKE|rcsb pdb:5PKF|rcsb pdb:5PKG|rcsb pdb:5PKH|rcsb pdb:5PKI|rcsb pdb:5PKJ|rcsb pdb:5PKK|rcsb pdb:5PKL|rcsb pdb:5PKM|rcsb pdb:5PKN|rcsb pdb:5PKO|rcsb pdb:5PKP|rcsb pdb:5PKQ|rcsb pdb:5PKR|rcsb pdb:5PKS|rcsb pdb:5PKT|rcsb pdb:5PKU|rcsb pdb:5PKV|rcsb pdb:5PKW|rcsb pdb:5PKX|rcsb pdb:5PKY|rcsb pdb:5PKZ|rcsb pdb:5PL0|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072562"(blood microparticle)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|mint:Q6B0I6|rcsb pdb:3DXT|rcsb pdb:3DXU|rcsb pdb:4D6Q|rcsb pdb:4D6R|rcsb pdb:4D6S|rcsb pdb:4HON|rcsb pdb:5PL2|rcsb pdb:5PL3|rcsb pdb:5PL1|rcsb pdb:5PL4|rcsb pdb:5PL5|rcsb pdb:5PL6|rcsb pdb:5PL7|rcsb pdb:5PL8|rcsb pdb:5PL9|rcsb pdb:5PLA|rcsb pdb:5PLB|rcsb pdb:5PLC|rcsb pdb:5PLD|rcsb pdb:5PLE|rcsb pdb:5PLF|rcsb pdb:5PLG|rcsb pdb:5PLH|rcsb pdb:5PLI|rcsb pdb:5PLJ|rcsb pdb:5PLK|rcsb pdb:5PLL|rcsb pdb:5PLM|rcsb pdb:5PLN|rcsb pdb:5PLO|rcsb pdb:5PLP|rcsb pdb:5PLQ|rcsb pdb:5PLR|rcsb pdb:5PLS|rcsb pdb:5F5A|rcsb pdb:5F5C|rcsb pdb:5FP4|rcsb pdb:5FP7|rcsb pdb:5FP8|rcsb pdb:5FP9|rcsb pdb:5FPA|rcsb pdb:5FPB|rcsb pdb:5PH0|rcsb pdb:5PH1|rcsb pdb:5PH2|rcsb pdb:5PH3|rcsb pdb:5PH4|rcsb pdb:4HOO|rcsb pdb:5PH5|rcsb pdb:5PH6|rcsb pdb:5PH7|rcsb pdb:5PH8|rcsb pdb:5PH9|rcsb pdb:5PHA|rcsb pdb:5PHB|rcsb pdb:5PHC|rcsb pdb:5PHD|rcsb pdb:5PHE|rcsb pdb:5PLU|rcsb pdb:5PLV|rcsb pdb:5PLW|rcsb pdb:5PLX|rcsb pdb:5PLY|rcsb pdb:5PLZ|rcsb pdb:5PM0|rcsb pdb:5PM1|rcsb pdb:5PM2|rcsb pdb:5PM3|rcsb pdb:5PM4|rcsb pdb:5PM5|rcsb pdb:5PM6|rcsb pdb:5PM7|rcsb pdb:5PM8|rcsb pdb:5PM9|rcsb pdb:5PMA|rcsb pdb:5PMB|rcsb pdb:5PMC|rcsb pdb:5PMD|rcsb pdb:5PME|rcsb pdb:5PMF|rcsb pdb:5PMG|rcsb pdb:5PMH|rcsb pdb:5PMI|rcsb pdb:5PMJ|rcsb pdb:5PMK|rcsb pdb:5PML|rcsb pdb:5PMM|rcsb pdb:5PMN|rcsb pdb:5PMO|rcsb pdb:5PMP|rcsb pdb:5PMQ|rcsb pdb:5PMR|rcsb pdb:5PMS|rcsb pdb:5PMT|rcsb pdb:5PMU|rcsb pdb:5PMV|rcsb pdb:5PMW|rcsb pdb:5PMX|rcsb pdb:5PMY|rcsb pdb:5PMZ|rcsb pdb:5PN0|rcsb pdb:5PN1|rcsb pdb:5PN2|rcsb pdb:5PN3|rcsb pdb:5PN4|rcsb pdb:5PN5|rcsb pdb:5PN6|rcsb pdb:5PN7|rcsb pdb:5PN8|rcsb pdb:5PN9|rcsb pdb:5PNA|rcsb pdb:5PNB|rcsb pdb:5PNC|rcsb pdb:5PND|rcsb pdb:5PNE|rcsb pdb:5PNF|rcsb pdb:5PNG|rcsb pdb:5PNH|rcsb pdb:5PNI|rcsb pdb:5PNJ|rcsb pdb:5PNK|rcsb pdb:5PNL|rcsb pdb:5PNM|rcsb pdb:5PLT|rcsb pdb:5PNN|rcsb pdb:5PNO|rcsb pdb:5PNP|rcsb pdb:5PNQ|rcsb pdb:5PNR|rcsb pdb:5PNS|rcsb pdb:5PNU|rcsb pdb:5PNV|rcsb pdb:5PNW|rcsb pdb:6ETE|rcsb pdb:6ETG|rcsb pdb:6ETS|rcsb pdb:5PHJ|rcsb pdb:5PHK|rcsb pdb:5PHL|rcsb pdb:5PHM|rcsb pdb:5PHN|rcsb pdb:5PHO|rcsb pdb:5PHP|rcsb pdb:5PHQ|rcsb pdb:5PHR|rcsb pdb:5PHS|rcsb pdb:5PHT|rcsb pdb:5PHU|rcsb pdb:5PHV|rcsb pdb:5PHF|rcsb pdb:5PHG|rcsb pdb:5PHH|rcsb pdb:5PHI|rcsb pdb:5PHW|rcsb pdb:5PHX|rcsb pdb:5PHY|rcsb pdb:5PHZ|rcsb pdb:5PI0|rcsb pdb:5PI1|rcsb pdb:5PI2|rcsb pdb:5PI3|rcsb pdb:5PI4|dip:DIP-29606N refseq:NP_005331.1|go:"GO:0016787"(hydrolase activity)|go:"GO:0043530"(adenosine 5'-monophosphoramidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|interpro:IPR001310("Histidine triad (HIT) protein")|interpro:IPR011146(Histidine triad-like motif)|interpro:IPR019808|interpro:IPR036265|mint:P49773|rcsb pdb:1AV5|rcsb pdb:1KPA|rcsb pdb:1KPB|rcsb pdb:1KPC|rcsb pdb:1KPE|rcsb pdb:1KPF|rcsb pdb:3TW2|ensembl:ENSG00000169567(gene)|ensembl:ENST00000304043(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000166"(nucleotide binding)|rcsb pdb:4EQE|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|rcsb pdb:4EQG|go:"GO:0005654"(nucleoplasm)|rcsb pdb:4EQH|rcsb pdb:4ZKL|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007165"(signal transduction)|go:"GO:0009154"(purine ribonucleotide catabolic process)|rcsb pdb:4ZKV|rcsb pdb:5ED3|rcsb pdb:5ED6|rcsb pdb:5EMT|rcsb pdb:5I2E|rcsb pdb:5I2F|rcsb pdb:5IPB|rcsb pdb:5IPC|rcsb pdb:5IPD|rcsb pdb:5IPE|rcsb pdb:5KLY|rcsb pdb:5KLZ|rcsb pdb:5KM0|rcsb pdb:5KM1|rcsb pdb:5KM2|rcsb pdb:5KM3|rcsb pdb:5KM4|rcsb pdb:5KM6|rcsb pdb:5KMA|rcsb pdb:5KMB|rcsb pdb:5KMC|rcsb pdb:5O8I|rcsb pdb:5WA8|rcsb pdb:5WA9|rcsb pdb:5WAA|rcsb pdb:6B42|rcsb pdb:6G9Z|rcsb pdb:6J53|rcsb pdb:6J58|rcsb pdb:6J5S|rcsb pdb:6J5Z|rcsb pdb:6J64|rcsb pdb:6J65|rcsb pdb:6N3V|rcsb pdb:6N3W|rcsb pdb:6N3X|rcsb pdb:6N3Y|rcsb pdb:6YQM - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:svQfKWBCSAPSGFAV5YPZXFvcqkk9606 rogid:vXotU/cqS8hSHeBmCk30zSQ9k/E9606 rigid:7fqj2Gju3X4HbV0gQNAzWx9cUhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6B0I6 uniprotkb:Q13464 intact:EBI-4311651|uniprotkb:Q9NW76|uniprotkb:B3KPC4|uniprotkb:Q9NT41|uniprotkb:Q0VF39|ensembl:ENSP00000334181|ensembl:ENSP00000460897|ensembl:ENSP00000482224 intact:EBI-876651|uniprotkb:B0YJ91|uniprotkb:Q2KHM4|uniprotkb:Q59GZ4|ensembl:ENSP00000382697 psi-mi:kdm4d_human(display_long)|uniprotkb:KDM4D(gene name)|psi-mi:KDM4D(display_short)|uniprotkb:JHDM3D(gene name synonym)|uniprotkb:JMJD2D(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3D(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2D(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4D"(gene name synonym) psi-mi:rock1_human(display_long)|uniprotkb:Rho-associated, coiled-coil-containing protein kinase 1(gene name synonym)|uniprotkb:p160 ROCK-1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-35(gene name synonym)|uniprotkb:ROCK1(gene name)|psi-mi:ROCK1(display_short)|uniprotkb:Rho-associated, coiled-coil-containing protein kinase I(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480104|imex:IM-26985-481 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060509.2|rcsb pdb:5PI6|rcsb pdb:5PI7|rcsb pdb:5PI8|rcsb pdb:5PI9|rcsb pdb:5PIA|rcsb pdb:5PIB|rcsb pdb:5PIC|rcsb pdb:5PID|rcsb pdb:5PIE|rcsb pdb:5PIF|rcsb pdb:5PIG|rcsb pdb:5PIH|rcsb pdb:5PII|rcsb pdb:5PIJ|rcsb pdb:5PIK|rcsb pdb:5PIL|rcsb pdb:5PIM|rcsb pdb:5PIN|rcsb pdb:5PIO|rcsb pdb:5PIP|rcsb pdb:5PIQ|rcsb pdb:5PIR|rcsb pdb:5PIS|rcsb pdb:5PIT|rcsb pdb:5PIU|rcsb pdb:5PIV|rcsb pdb:5PIW|rcsb pdb:5PIX|rcsb pdb:5PIY|rcsb pdb:5PIZ|rcsb pdb:5PJ0|rcsb pdb:5PI5|rcsb pdb:5PJ1|rcsb pdb:5PJ2|rcsb pdb:5PJ3|rcsb pdb:5PJ4|rcsb pdb:5PJ6|rcsb pdb:5PJ7|rcsb pdb:5PJ8|rcsb pdb:5PJ9|rcsb pdb:5PJA|rcsb pdb:5PJB|rcsb pdb:5PJC|rcsb pdb:5PJD|rcsb pdb:5PJE|rcsb pdb:5PJF|rcsb pdb:5PJG|rcsb pdb:5PJ5|rcsb pdb:5PJH|rcsb pdb:5PJI|rcsb pdb:5PJJ|rcsb pdb:5PJK|rcsb pdb:5PJL|rcsb pdb:5PJM|rcsb pdb:5PJN|rcsb pdb:5PJO|rcsb pdb:5PJP|rcsb pdb:5PJQ|rcsb pdb:5PJR|rcsb pdb:5PJS|rcsb pdb:6ETT|rcsb pdb:6ETU|rcsb pdb:5PJT|rcsb pdb:6ETV|rcsb pdb:6ETW|rcsb pdb:6F5Q|rcsb pdb:6F5R|rcsb pdb:6F5S|rcsb pdb:6F5T|rcsb pdb:6H0W|rcsb pdb:6H0X|rcsb pdb:6H0Y|rcsb pdb:6H0Z|rcsb pdb:6H10|rcsb pdb:6H11|reactome:R-HSA-3214842|ensembl:ENSG00000186280(gene)|ensembl:ENST00000335080(transcript)|ensembl:ENST00000536741(transcript)|ensembl:ENST00000610872(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|rcsb pdb:5PJV|rcsb pdb:5PJW|rcsb pdb:5PJX|rcsb pdb:5PJY|rcsb pdb:5PJZ|rcsb pdb:5PK0|rcsb pdb:5PK1|rcsb pdb:5PK2|rcsb pdb:5PJU|rcsb pdb:5PK3|rcsb pdb:5PK4|rcsb pdb:5PK5|rcsb pdb:5PK6|rcsb pdb:5PK7|rcsb pdb:5PK8|rcsb pdb:5PK9|rcsb pdb:5PKA|rcsb pdb:5PKB|rcsb pdb:5PKC|rcsb pdb:5PKD|rcsb pdb:5PKE|rcsb pdb:5PKF|rcsb pdb:5PKG|rcsb pdb:5PKH|rcsb pdb:5PKI|rcsb pdb:5PKJ|rcsb pdb:5PKK|rcsb pdb:5PKL|rcsb pdb:5PKM|rcsb pdb:5PKN|rcsb pdb:5PKO|rcsb pdb:5PKP|rcsb pdb:5PKQ|rcsb pdb:5PKR|rcsb pdb:5PKS|rcsb pdb:5PKT|rcsb pdb:5PKU|rcsb pdb:5PKV|rcsb pdb:5PKW|rcsb pdb:5PKX|rcsb pdb:5PKY|rcsb pdb:5PKZ|rcsb pdb:5PL0|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072562"(blood microparticle)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|mint:Q6B0I6|rcsb pdb:3DXT|rcsb pdb:3DXU|rcsb pdb:4D6Q|rcsb pdb:4D6R|rcsb pdb:4D6S|rcsb pdb:4HON|rcsb pdb:5PL2|rcsb pdb:5PL3|rcsb pdb:5PL1|rcsb pdb:5PL4|rcsb pdb:5PL5|rcsb pdb:5PL6|rcsb pdb:5PL7|rcsb pdb:5PL8|rcsb pdb:5PL9|rcsb pdb:5PLA|rcsb pdb:5PLB|rcsb pdb:5PLC|rcsb pdb:5PLD|rcsb pdb:5PLE|rcsb pdb:5PLF|rcsb pdb:5PLG|rcsb pdb:5PLH|rcsb pdb:5PLI|rcsb pdb:5PLJ|rcsb pdb:5PLK|rcsb pdb:5PLL|rcsb pdb:5PLM|rcsb pdb:5PLN|rcsb pdb:5PLO|rcsb pdb:5PLP|rcsb pdb:5PLQ|rcsb pdb:5PLR|rcsb pdb:5PLS|rcsb pdb:5F5A|rcsb pdb:5F5C|rcsb pdb:5FP4|rcsb pdb:5FP7|rcsb pdb:5FP8|rcsb pdb:5FP9|rcsb pdb:5FPA|rcsb pdb:5FPB|rcsb pdb:5PH0|rcsb pdb:5PH1|rcsb pdb:5PH2|rcsb pdb:5PH3|rcsb pdb:5PH4|rcsb pdb:4HOO|rcsb pdb:5PH5|rcsb pdb:5PH6|rcsb pdb:5PH7|rcsb pdb:5PH8|rcsb pdb:5PH9|rcsb pdb:5PHA|rcsb pdb:5PHB|rcsb pdb:5PHC|rcsb pdb:5PHD|rcsb pdb:5PHE|rcsb pdb:5PLU|rcsb pdb:5PLV|rcsb pdb:5PLW|rcsb pdb:5PLX|rcsb pdb:5PLY|rcsb pdb:5PLZ|rcsb pdb:5PM0|rcsb pdb:5PM1|rcsb pdb:5PM2|rcsb pdb:5PM3|rcsb pdb:5PM4|rcsb pdb:5PM5|rcsb pdb:5PM6|rcsb pdb:5PM7|rcsb pdb:5PM8|rcsb pdb:5PM9|rcsb pdb:5PMA|rcsb pdb:5PMB|rcsb pdb:5PMC|rcsb pdb:5PMD|rcsb pdb:5PME|rcsb pdb:5PMF|rcsb pdb:5PMG|rcsb pdb:5PMH|rcsb pdb:5PMI|rcsb pdb:5PMJ|rcsb pdb:5PMK|rcsb pdb:5PML|rcsb pdb:5PMM|rcsb pdb:5PMN|rcsb pdb:5PMO|rcsb pdb:5PMP|rcsb pdb:5PMQ|rcsb pdb:5PMR|rcsb pdb:5PMS|rcsb pdb:5PMT|rcsb pdb:5PMU|rcsb pdb:5PMV|rcsb pdb:5PMW|rcsb pdb:5PMX|rcsb pdb:5PMY|rcsb pdb:5PMZ|rcsb pdb:5PN0|rcsb pdb:5PN1|rcsb pdb:5PN2|rcsb pdb:5PN3|rcsb pdb:5PN4|rcsb pdb:5PN5|rcsb pdb:5PN6|rcsb pdb:5PN7|rcsb pdb:5PN8|rcsb pdb:5PN9|rcsb pdb:5PNA|rcsb pdb:5PNB|rcsb pdb:5PNC|rcsb pdb:5PND|rcsb pdb:5PNE|rcsb pdb:5PNF|rcsb pdb:5PNG|rcsb pdb:5PNH|rcsb pdb:5PNI|rcsb pdb:5PNJ|rcsb pdb:5PNK|rcsb pdb:5PNL|rcsb pdb:5PNM|rcsb pdb:5PLT|rcsb pdb:5PNN|rcsb pdb:5PNO|rcsb pdb:5PNP|rcsb pdb:5PNQ|rcsb pdb:5PNR|rcsb pdb:5PNS|rcsb pdb:5PNU|rcsb pdb:5PNV|rcsb pdb:5PNW|rcsb pdb:6ETE|rcsb pdb:6ETG|rcsb pdb:6ETS|rcsb pdb:5PHJ|rcsb pdb:5PHK|rcsb pdb:5PHL|rcsb pdb:5PHM|rcsb pdb:5PHN|rcsb pdb:5PHO|rcsb pdb:5PHP|rcsb pdb:5PHQ|rcsb pdb:5PHR|rcsb pdb:5PHS|rcsb pdb:5PHT|rcsb pdb:5PHU|rcsb pdb:5PHV|rcsb pdb:5PHF|rcsb pdb:5PHG|rcsb pdb:5PHH|rcsb pdb:5PHI|rcsb pdb:5PHW|rcsb pdb:5PHX|rcsb pdb:5PHY|rcsb pdb:5PHZ|rcsb pdb:5PI0|rcsb pdb:5PI1|rcsb pdb:5PI2|rcsb pdb:5PI3|rcsb pdb:5PI4|dip:DIP-29606N refseq:NP_005397.1|dip:DIP-35645N|ensembl:ENSG00000067900(gene)|ensembl:ENST00000399799(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001726"(ruffle)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006939"(smooth muscle contraction)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019828"(aspartic-type endopeptidase inhibitor activity)|go:"GO:0022614"(membrane to membrane docking)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032059"(bleb)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035509"(negative regulation of myosin-light-chain-phosphatase activity)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045616"(regulation of keratinocyte differentiation)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050900"(leukocyte migration)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0051045"(negative regulation of membrane protein ectodomain proteolysis)|go:"GO:0051451"(myoblast migration)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0070168"(negative regulation of biomineral tissue development)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0071559"(response to transforming growth factor beta)|go:"GO:0072518"(Rho-dependent protein serine/threonine kinase activity)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090521"(glomerular visceral epithelial cell migration)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0110061"(regulation of angiotensin-activated signaling pathway)|go:"GO:0140058"(neuron projection arborization)|go:"GO:1900223"(positive regulation of amyloid-beta clearance)|go:"GO:1900242"(regulation of synaptic vesicle endocytosis)|go:"GO:1901888"(regulation of cell junction assembly)|go:"GO:1902003"(regulation of amyloid-beta formation)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902992"(negative regulation of amyloid precursor protein catabolic process)|go:"GO:1903140"(regulation of establishment of endothelial barrier)|go:"GO:1903347"(negative regulation of bicellular tight junction assembly)|go:"GO:1905205"(positive regulation of connective tissue replacement)|go:"GO:1990776"(response to angiotensin)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000145"(regulation of cell motility)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015008(Rho Binding)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020684|interpro:IPR037310|mint:Q13464|rcsb pdb:1S1C|rcsb pdb:2ESM|rcsb pdb:2ETK|rcsb pdb:2ETR|rcsb pdb:2V55|rcsb pdb:3D9V|rcsb pdb:3NCZ|rcsb pdb:3NDM|rcsb pdb:3O0Z|rcsb pdb:3TV7|rcsb pdb:3TWJ|rcsb pdb:3V8S|rcsb pdb:4L2W|rcsb pdb:4W7P|rcsb pdb:4YVC|rcsb pdb:4YVE|rcsb pdb:5BML|rcsb pdb:5F5P|rcsb pdb:5HVU|rcsb pdb:5KKS|rcsb pdb:5KKT|rcsb pdb:5UZJ|rcsb pdb:5WNE|rcsb pdb:5WNF|rcsb pdb:5WNG|rcsb pdb:5WNH|rcsb pdb:6E9W|rcsb pdb:7JOU|reactome:R-HSA-111465|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-4420097|reactome:R-HSA-5627117|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013407|reactome:R-HSA-9013422|reactome:R-HSA-9679191|reactome:R-HSA-9696264 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:svQfKWBCSAPSGFAV5YPZXFvcqkk9606 rogid:1YIjRC+RHWK9pmiq8kSBFiZcll49606 rigid:7fqj2Gju3X4HbV0gQNAzWx9cUhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6B0I6 uniprotkb:Q92820 intact:EBI-4311651|uniprotkb:Q9NW76|uniprotkb:B3KPC4|uniprotkb:Q9NT41|uniprotkb:Q0VF39|ensembl:ENSP00000334181|ensembl:ENSP00000460897|ensembl:ENSP00000482224 intact:EBI-3045534|ensembl:ENSP00000260118 psi-mi:kdm4d_human(display_long)|uniprotkb:KDM4D(gene name)|psi-mi:KDM4D(display_short)|uniprotkb:JHDM3D(gene name synonym)|uniprotkb:JMJD2D(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3D(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2D(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4D"(gene name synonym) psi-mi:ggh_human(display_long)|uniprotkb:GGH(gene name)|psi-mi:GGH(display_short)|uniprotkb:Conjugase(gene name synonym)|uniprotkb:GH(gene name synonym)|uniprotkb:Gamma-Glu-X carboxypeptidase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480104|imex:IM-26985-481 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060509.2|rcsb pdb:5PI6|rcsb pdb:5PI7|rcsb pdb:5PI8|rcsb pdb:5PI9|rcsb pdb:5PIA|rcsb pdb:5PIB|rcsb pdb:5PIC|rcsb pdb:5PID|rcsb pdb:5PIE|rcsb pdb:5PIF|rcsb pdb:5PIG|rcsb pdb:5PIH|rcsb pdb:5PII|rcsb pdb:5PIJ|rcsb pdb:5PIK|rcsb pdb:5PIL|rcsb pdb:5PIM|rcsb pdb:5PIN|rcsb pdb:5PIO|rcsb pdb:5PIP|rcsb pdb:5PIQ|rcsb pdb:5PIR|rcsb pdb:5PIS|rcsb pdb:5PIT|rcsb pdb:5PIU|rcsb pdb:5PIV|rcsb pdb:5PIW|rcsb pdb:5PIX|rcsb pdb:5PIY|rcsb pdb:5PIZ|rcsb pdb:5PJ0|rcsb pdb:5PI5|rcsb pdb:5PJ1|rcsb pdb:5PJ2|rcsb pdb:5PJ3|rcsb pdb:5PJ4|rcsb pdb:5PJ6|rcsb pdb:5PJ7|rcsb pdb:5PJ8|rcsb pdb:5PJ9|rcsb pdb:5PJA|rcsb pdb:5PJB|rcsb pdb:5PJC|rcsb pdb:5PJD|rcsb pdb:5PJE|rcsb pdb:5PJF|rcsb pdb:5PJG|rcsb pdb:5PJ5|rcsb pdb:5PJH|rcsb pdb:5PJI|rcsb pdb:5PJJ|rcsb pdb:5PJK|rcsb pdb:5PJL|rcsb pdb:5PJM|rcsb pdb:5PJN|rcsb pdb:5PJO|rcsb pdb:5PJP|rcsb pdb:5PJQ|rcsb pdb:5PJR|rcsb pdb:5PJS|rcsb pdb:6ETT|rcsb pdb:6ETU|rcsb pdb:5PJT|rcsb pdb:6ETV|rcsb pdb:6ETW|rcsb pdb:6F5Q|rcsb pdb:6F5R|rcsb pdb:6F5S|rcsb pdb:6F5T|rcsb pdb:6H0W|rcsb pdb:6H0X|rcsb pdb:6H0Y|rcsb pdb:6H0Z|rcsb pdb:6H10|rcsb pdb:6H11|reactome:R-HSA-3214842|ensembl:ENSG00000186280(gene)|ensembl:ENST00000335080(transcript)|ensembl:ENST00000536741(transcript)|ensembl:ENST00000610872(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|rcsb pdb:5PJV|rcsb pdb:5PJW|rcsb pdb:5PJX|rcsb pdb:5PJY|rcsb pdb:5PJZ|rcsb pdb:5PK0|rcsb pdb:5PK1|rcsb pdb:5PK2|rcsb pdb:5PJU|rcsb pdb:5PK3|rcsb pdb:5PK4|rcsb pdb:5PK5|rcsb pdb:5PK6|rcsb pdb:5PK7|rcsb pdb:5PK8|rcsb pdb:5PK9|rcsb pdb:5PKA|rcsb pdb:5PKB|rcsb pdb:5PKC|rcsb pdb:5PKD|rcsb pdb:5PKE|rcsb pdb:5PKF|rcsb pdb:5PKG|rcsb pdb:5PKH|rcsb pdb:5PKI|rcsb pdb:5PKJ|rcsb pdb:5PKK|rcsb pdb:5PKL|rcsb pdb:5PKM|rcsb pdb:5PKN|rcsb pdb:5PKO|rcsb pdb:5PKP|rcsb pdb:5PKQ|rcsb pdb:5PKR|rcsb pdb:5PKS|rcsb pdb:5PKT|rcsb pdb:5PKU|rcsb pdb:5PKV|rcsb pdb:5PKW|rcsb pdb:5PKX|rcsb pdb:5PKY|rcsb pdb:5PKZ|rcsb pdb:5PL0|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072562"(blood microparticle)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|mint:Q6B0I6|rcsb pdb:3DXT|rcsb pdb:3DXU|rcsb pdb:4D6Q|rcsb pdb:4D6R|rcsb pdb:4D6S|rcsb pdb:4HON|rcsb pdb:5PL2|rcsb pdb:5PL3|rcsb pdb:5PL1|rcsb pdb:5PL4|rcsb pdb:5PL5|rcsb pdb:5PL6|rcsb pdb:5PL7|rcsb pdb:5PL8|rcsb pdb:5PL9|rcsb pdb:5PLA|rcsb pdb:5PLB|rcsb pdb:5PLC|rcsb pdb:5PLD|rcsb pdb:5PLE|rcsb pdb:5PLF|rcsb pdb:5PLG|rcsb pdb:5PLH|rcsb pdb:5PLI|rcsb pdb:5PLJ|rcsb pdb:5PLK|rcsb pdb:5PLL|rcsb pdb:5PLM|rcsb pdb:5PLN|rcsb pdb:5PLO|rcsb pdb:5PLP|rcsb pdb:5PLQ|rcsb pdb:5PLR|rcsb pdb:5PLS|rcsb pdb:5F5A|rcsb pdb:5F5C|rcsb pdb:5FP4|rcsb pdb:5FP7|rcsb pdb:5FP8|rcsb pdb:5FP9|rcsb pdb:5FPA|rcsb pdb:5FPB|rcsb pdb:5PH0|rcsb pdb:5PH1|rcsb pdb:5PH2|rcsb pdb:5PH3|rcsb pdb:5PH4|rcsb pdb:4HOO|rcsb pdb:5PH5|rcsb pdb:5PH6|rcsb pdb:5PH7|rcsb pdb:5PH8|rcsb pdb:5PH9|rcsb pdb:5PHA|rcsb pdb:5PHB|rcsb pdb:5PHC|rcsb pdb:5PHD|rcsb pdb:5PHE|rcsb pdb:5PLU|rcsb pdb:5PLV|rcsb pdb:5PLW|rcsb pdb:5PLX|rcsb pdb:5PLY|rcsb pdb:5PLZ|rcsb pdb:5PM0|rcsb pdb:5PM1|rcsb pdb:5PM2|rcsb pdb:5PM3|rcsb pdb:5PM4|rcsb pdb:5PM5|rcsb pdb:5PM6|rcsb pdb:5PM7|rcsb pdb:5PM8|rcsb pdb:5PM9|rcsb pdb:5PMA|rcsb pdb:5PMB|rcsb pdb:5PMC|rcsb pdb:5PMD|rcsb pdb:5PME|rcsb pdb:5PMF|rcsb pdb:5PMG|rcsb pdb:5PMH|rcsb pdb:5PMI|rcsb pdb:5PMJ|rcsb pdb:5PMK|rcsb pdb:5PML|rcsb pdb:5PMM|rcsb pdb:5PMN|rcsb pdb:5PMO|rcsb pdb:5PMP|rcsb pdb:5PMQ|rcsb pdb:5PMR|rcsb pdb:5PMS|rcsb pdb:5PMT|rcsb pdb:5PMU|rcsb pdb:5PMV|rcsb pdb:5PMW|rcsb pdb:5PMX|rcsb pdb:5PMY|rcsb pdb:5PMZ|rcsb pdb:5PN0|rcsb pdb:5PN1|rcsb pdb:5PN2|rcsb pdb:5PN3|rcsb pdb:5PN4|rcsb pdb:5PN5|rcsb pdb:5PN6|rcsb pdb:5PN7|rcsb pdb:5PN8|rcsb pdb:5PN9|rcsb pdb:5PNA|rcsb pdb:5PNB|rcsb pdb:5PNC|rcsb pdb:5PND|rcsb pdb:5PNE|rcsb pdb:5PNF|rcsb pdb:5PNG|rcsb pdb:5PNH|rcsb pdb:5PNI|rcsb pdb:5PNJ|rcsb pdb:5PNK|rcsb pdb:5PNL|rcsb pdb:5PNM|rcsb pdb:5PLT|rcsb pdb:5PNN|rcsb pdb:5PNO|rcsb pdb:5PNP|rcsb pdb:5PNQ|rcsb pdb:5PNR|rcsb pdb:5PNS|rcsb pdb:5PNU|rcsb pdb:5PNV|rcsb pdb:5PNW|rcsb pdb:6ETE|rcsb pdb:6ETG|rcsb pdb:6ETS|rcsb pdb:5PHJ|rcsb pdb:5PHK|rcsb pdb:5PHL|rcsb pdb:5PHM|rcsb pdb:5PHN|rcsb pdb:5PHO|rcsb pdb:5PHP|rcsb pdb:5PHQ|rcsb pdb:5PHR|rcsb pdb:5PHS|rcsb pdb:5PHT|rcsb pdb:5PHU|rcsb pdb:5PHV|rcsb pdb:5PHF|rcsb pdb:5PHG|rcsb pdb:5PHH|rcsb pdb:5PHI|rcsb pdb:5PHW|rcsb pdb:5PHX|rcsb pdb:5PHY|rcsb pdb:5PHZ|rcsb pdb:5PI0|rcsb pdb:5PI1|rcsb pdb:5PI2|rcsb pdb:5PI3|rcsb pdb:5PI4|dip:DIP-29606N ensembl:ENSG00000137563(gene)|ensembl:ENST00000260118(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0008238"(exopeptidase activity)|go:"GO:0008242"(omega peptidase activity)|go:"GO:0010043"(response to zinc ion)|go:"GO:0032868"(response to insulin)|go:"GO:0034722"(gamma-glutamyl-peptidase activity)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0045471"(response to ethanol)|go:"GO:0046900"(tetrahydrofolylpolyglutamate metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070500"(poly-gamma-glutamate metabolic process)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR011697(Peptidase C26)|interpro:IPR015527(Peptidase C26, gamma-glutamyl hydrolase)|interpro:IPR029062|mint:Q92820|rcsb pdb:1L9X|reactome:R-HSA-6798695|refseq:NP_003869.1 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:svQfKWBCSAPSGFAV5YPZXFvcqkk9606 rogid:QjPbv+fLXWnf6gmW2PsXVuyatR49606 rigid:7fqj2Gju3X4HbV0gQNAzWx9cUhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6B0I6 uniprotkb:Q15428 intact:EBI-4311651|uniprotkb:Q9NW76|uniprotkb:B3KPC4|uniprotkb:Q9NT41|uniprotkb:Q0VF39|ensembl:ENSP00000334181|ensembl:ENSP00000460897|ensembl:ENSP00000482224 intact:EBI-2462271|uniprotkb:O75245|uniprotkb:B2RBU1|uniprotkb:D6W605|intact:EBI-28985293|ensembl:ENSP00000221494 psi-mi:kdm4d_human(display_long)|uniprotkb:KDM4D(gene name)|psi-mi:KDM4D(display_short)|uniprotkb:JHDM3D(gene name synonym)|uniprotkb:JMJD2D(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3D(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2D(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4D"(gene name synonym) psi-mi:sf3a2_human(display_long)|uniprotkb:SF3A2(gene name)|psi-mi:SF3A2(display_short)|uniprotkb:SAP62(gene name synonym)|uniprotkb:Spliceosome-associated protein 62(gene name synonym)|uniprotkb:SF3a66(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480104|imex:IM-26985-481 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060509.2|rcsb pdb:5PI6|rcsb pdb:5PI7|rcsb pdb:5PI8|rcsb pdb:5PI9|rcsb pdb:5PIA|rcsb pdb:5PIB|rcsb pdb:5PIC|rcsb pdb:5PID|rcsb pdb:5PIE|rcsb pdb:5PIF|rcsb pdb:5PIG|rcsb pdb:5PIH|rcsb pdb:5PII|rcsb pdb:5PIJ|rcsb pdb:5PIK|rcsb pdb:5PIL|rcsb pdb:5PIM|rcsb pdb:5PIN|rcsb pdb:5PIO|rcsb pdb:5PIP|rcsb pdb:5PIQ|rcsb pdb:5PIR|rcsb pdb:5PIS|rcsb pdb:5PIT|rcsb pdb:5PIU|rcsb pdb:5PIV|rcsb pdb:5PIW|rcsb pdb:5PIX|rcsb pdb:5PIY|rcsb pdb:5PIZ|rcsb pdb:5PJ0|rcsb pdb:5PI5|rcsb pdb:5PJ1|rcsb pdb:5PJ2|rcsb pdb:5PJ3|rcsb pdb:5PJ4|rcsb pdb:5PJ6|rcsb pdb:5PJ7|rcsb pdb:5PJ8|rcsb pdb:5PJ9|rcsb pdb:5PJA|rcsb pdb:5PJB|rcsb pdb:5PJC|rcsb pdb:5PJD|rcsb pdb:5PJE|rcsb pdb:5PJF|rcsb pdb:5PJG|rcsb pdb:5PJ5|rcsb pdb:5PJH|rcsb pdb:5PJI|rcsb pdb:5PJJ|rcsb pdb:5PJK|rcsb pdb:5PJL|rcsb pdb:5PJM|rcsb pdb:5PJN|rcsb pdb:5PJO|rcsb pdb:5PJP|rcsb pdb:5PJQ|rcsb pdb:5PJR|rcsb pdb:5PJS|rcsb pdb:6ETT|rcsb pdb:6ETU|rcsb pdb:5PJT|rcsb pdb:6ETV|rcsb pdb:6ETW|rcsb pdb:6F5Q|rcsb pdb:6F5R|rcsb pdb:6F5S|rcsb pdb:6F5T|rcsb pdb:6H0W|rcsb pdb:6H0X|rcsb pdb:6H0Y|rcsb pdb:6H0Z|rcsb pdb:6H10|rcsb pdb:6H11|reactome:R-HSA-3214842|ensembl:ENSG00000186280(gene)|ensembl:ENST00000335080(transcript)|ensembl:ENST00000536741(transcript)|ensembl:ENST00000610872(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|rcsb pdb:5PJV|rcsb pdb:5PJW|rcsb pdb:5PJX|rcsb pdb:5PJY|rcsb pdb:5PJZ|rcsb pdb:5PK0|rcsb pdb:5PK1|rcsb pdb:5PK2|rcsb pdb:5PJU|rcsb pdb:5PK3|rcsb pdb:5PK4|rcsb pdb:5PK5|rcsb pdb:5PK6|rcsb pdb:5PK7|rcsb pdb:5PK8|rcsb pdb:5PK9|rcsb pdb:5PKA|rcsb pdb:5PKB|rcsb pdb:5PKC|rcsb pdb:5PKD|rcsb pdb:5PKE|rcsb pdb:5PKF|rcsb pdb:5PKG|rcsb pdb:5PKH|rcsb pdb:5PKI|rcsb pdb:5PKJ|rcsb pdb:5PKK|rcsb pdb:5PKL|rcsb pdb:5PKM|rcsb pdb:5PKN|rcsb pdb:5PKO|rcsb pdb:5PKP|rcsb pdb:5PKQ|rcsb pdb:5PKR|rcsb pdb:5PKS|rcsb pdb:5PKT|rcsb pdb:5PKU|rcsb pdb:5PKV|rcsb pdb:5PKW|rcsb pdb:5PKX|rcsb pdb:5PKY|rcsb pdb:5PKZ|rcsb pdb:5PL0|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072562"(blood microparticle)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|mint:Q6B0I6|rcsb pdb:3DXT|rcsb pdb:3DXU|rcsb pdb:4D6Q|rcsb pdb:4D6R|rcsb pdb:4D6S|rcsb pdb:4HON|rcsb pdb:5PL2|rcsb pdb:5PL3|rcsb pdb:5PL1|rcsb pdb:5PL4|rcsb pdb:5PL5|rcsb pdb:5PL6|rcsb pdb:5PL7|rcsb pdb:5PL8|rcsb pdb:5PL9|rcsb pdb:5PLA|rcsb pdb:5PLB|rcsb pdb:5PLC|rcsb pdb:5PLD|rcsb pdb:5PLE|rcsb pdb:5PLF|rcsb pdb:5PLG|rcsb pdb:5PLH|rcsb pdb:5PLI|rcsb pdb:5PLJ|rcsb pdb:5PLK|rcsb pdb:5PLL|rcsb pdb:5PLM|rcsb pdb:5PLN|rcsb pdb:5PLO|rcsb pdb:5PLP|rcsb pdb:5PLQ|rcsb pdb:5PLR|rcsb pdb:5PLS|rcsb pdb:5F5A|rcsb pdb:5F5C|rcsb pdb:5FP4|rcsb pdb:5FP7|rcsb pdb:5FP8|rcsb pdb:5FP9|rcsb pdb:5FPA|rcsb pdb:5FPB|rcsb pdb:5PH0|rcsb pdb:5PH1|rcsb pdb:5PH2|rcsb pdb:5PH3|rcsb pdb:5PH4|rcsb pdb:4HOO|rcsb pdb:5PH5|rcsb pdb:5PH6|rcsb pdb:5PH7|rcsb pdb:5PH8|rcsb pdb:5PH9|rcsb pdb:5PHA|rcsb pdb:5PHB|rcsb pdb:5PHC|rcsb pdb:5PHD|rcsb pdb:5PHE|rcsb pdb:5PLU|rcsb pdb:5PLV|rcsb pdb:5PLW|rcsb pdb:5PLX|rcsb pdb:5PLY|rcsb pdb:5PLZ|rcsb pdb:5PM0|rcsb pdb:5PM1|rcsb pdb:5PM2|rcsb pdb:5PM3|rcsb pdb:5PM4|rcsb pdb:5PM5|rcsb pdb:5PM6|rcsb pdb:5PM7|rcsb pdb:5PM8|rcsb pdb:5PM9|rcsb pdb:5PMA|rcsb pdb:5PMB|rcsb pdb:5PMC|rcsb pdb:5PMD|rcsb pdb:5PME|rcsb pdb:5PMF|rcsb pdb:5PMG|rcsb pdb:5PMH|rcsb pdb:5PMI|rcsb pdb:5PMJ|rcsb pdb:5PMK|rcsb pdb:5PML|rcsb pdb:5PMM|rcsb pdb:5PMN|rcsb pdb:5PMO|rcsb pdb:5PMP|rcsb pdb:5PMQ|rcsb pdb:5PMR|rcsb pdb:5PMS|rcsb pdb:5PMT|rcsb pdb:5PMU|rcsb pdb:5PMV|rcsb pdb:5PMW|rcsb pdb:5PMX|rcsb pdb:5PMY|rcsb pdb:5PMZ|rcsb pdb:5PN0|rcsb pdb:5PN1|rcsb pdb:5PN2|rcsb pdb:5PN3|rcsb pdb:5PN4|rcsb pdb:5PN5|rcsb pdb:5PN6|rcsb pdb:5PN7|rcsb pdb:5PN8|rcsb pdb:5PN9|rcsb pdb:5PNA|rcsb pdb:5PNB|rcsb pdb:5PNC|rcsb pdb:5PND|rcsb pdb:5PNE|rcsb pdb:5PNF|rcsb pdb:5PNG|rcsb pdb:5PNH|rcsb pdb:5PNI|rcsb pdb:5PNJ|rcsb pdb:5PNK|rcsb pdb:5PNL|rcsb pdb:5PNM|rcsb pdb:5PLT|rcsb pdb:5PNN|rcsb pdb:5PNO|rcsb pdb:5PNP|rcsb pdb:5PNQ|rcsb pdb:5PNR|rcsb pdb:5PNS|rcsb pdb:5PNU|rcsb pdb:5PNV|rcsb pdb:5PNW|rcsb pdb:6ETE|rcsb pdb:6ETG|rcsb pdb:6ETS|rcsb pdb:5PHJ|rcsb pdb:5PHK|rcsb pdb:5PHL|rcsb pdb:5PHM|rcsb pdb:5PHN|rcsb pdb:5PHO|rcsb pdb:5PHP|rcsb pdb:5PHQ|rcsb pdb:5PHR|rcsb pdb:5PHS|rcsb pdb:5PHT|rcsb pdb:5PHU|rcsb pdb:5PHV|rcsb pdb:5PHF|rcsb pdb:5PHG|rcsb pdb:5PHH|rcsb pdb:5PHI|rcsb pdb:5PHW|rcsb pdb:5PHX|rcsb pdb:5PHY|rcsb pdb:5PHZ|rcsb pdb:5PI0|rcsb pdb:5PI1|rcsb pdb:5PI2|rcsb pdb:5PI3|rcsb pdb:5PI4|dip:DIP-29606N refseq:NP_009096.2|ensembl:ENSP00000221494|dip:DIP-42521N|ensembl:ENSG00000104897(gene)|ensembl:ENST00000221494(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016607"(nuclear speck)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1903241"(U2-type prespliceosome assembly)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR031781|interpro:IPR036236|mint:Q15428|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|reactome:R-HSA-72163 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:svQfKWBCSAPSGFAV5YPZXFvcqkk9606 rogid:ME4xzpqT37HjPl/xy683FS1Vns89606 rigid:7fqj2Gju3X4HbV0gQNAzWx9cUhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6B0I6 uniprotkb:Q9Y4F1 intact:EBI-4311651|uniprotkb:Q9NW76|uniprotkb:B3KPC4|uniprotkb:Q9NT41|uniprotkb:Q0VF39|ensembl:ENSP00000334181|ensembl:ENSP00000460897|ensembl:ENSP00000482224 intact:EBI-5235630|uniprotkb:Q6IQ29|uniprotkb:Q5JVI9|ensembl:ENSP00000322926 psi-mi:kdm4d_human(display_long)|uniprotkb:KDM4D(gene name)|psi-mi:KDM4D(display_short)|uniprotkb:JHDM3D(gene name synonym)|uniprotkb:JMJD2D(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3D(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2D(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4D"(gene name synonym) psi-mi:farp1_human(display_long)|uniprotkb:FARP1(gene name)|psi-mi:FARP1(display_short)|uniprotkb:CDEP(gene name synonym)|uniprotkb:PLEKHC2(gene name synonym)|uniprotkb:Chondrocyte-derived ezrin-like protein(gene name synonym)|uniprotkb:Pleckstrin homology domain-containing family C member 2(gene name synonym)|uniprotkb:FERM, RhoGEF and pleckstrin domain-containing protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480104|imex:IM-26985-481 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060509.2|rcsb pdb:5PI6|rcsb pdb:5PI7|rcsb pdb:5PI8|rcsb pdb:5PI9|rcsb pdb:5PIA|rcsb pdb:5PIB|rcsb pdb:5PIC|rcsb pdb:5PID|rcsb pdb:5PIE|rcsb pdb:5PIF|rcsb pdb:5PIG|rcsb pdb:5PIH|rcsb pdb:5PII|rcsb pdb:5PIJ|rcsb pdb:5PIK|rcsb pdb:5PIL|rcsb pdb:5PIM|rcsb pdb:5PIN|rcsb pdb:5PIO|rcsb pdb:5PIP|rcsb pdb:5PIQ|rcsb pdb:5PIR|rcsb pdb:5PIS|rcsb pdb:5PIT|rcsb pdb:5PIU|rcsb pdb:5PIV|rcsb pdb:5PIW|rcsb pdb:5PIX|rcsb pdb:5PIY|rcsb pdb:5PIZ|rcsb pdb:5PJ0|rcsb pdb:5PI5|rcsb pdb:5PJ1|rcsb pdb:5PJ2|rcsb pdb:5PJ3|rcsb pdb:5PJ4|rcsb pdb:5PJ6|rcsb pdb:5PJ7|rcsb pdb:5PJ8|rcsb pdb:5PJ9|rcsb pdb:5PJA|rcsb pdb:5PJB|rcsb pdb:5PJC|rcsb pdb:5PJD|rcsb pdb:5PJE|rcsb pdb:5PJF|rcsb pdb:5PJG|rcsb pdb:5PJ5|rcsb pdb:5PJH|rcsb pdb:5PJI|rcsb pdb:5PJJ|rcsb pdb:5PJK|rcsb pdb:5PJL|rcsb pdb:5PJM|rcsb pdb:5PJN|rcsb pdb:5PJO|rcsb pdb:5PJP|rcsb pdb:5PJQ|rcsb pdb:5PJR|rcsb pdb:5PJS|rcsb pdb:6ETT|rcsb pdb:6ETU|rcsb pdb:5PJT|rcsb pdb:6ETV|rcsb pdb:6ETW|rcsb pdb:6F5Q|rcsb pdb:6F5R|rcsb pdb:6F5S|rcsb pdb:6F5T|rcsb pdb:6H0W|rcsb pdb:6H0X|rcsb pdb:6H0Y|rcsb pdb:6H0Z|rcsb pdb:6H10|rcsb pdb:6H11|reactome:R-HSA-3214842|ensembl:ENSG00000186280(gene)|ensembl:ENST00000335080(transcript)|ensembl:ENST00000536741(transcript)|ensembl:ENST00000610872(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|rcsb pdb:5PJV|rcsb pdb:5PJW|rcsb pdb:5PJX|rcsb pdb:5PJY|rcsb pdb:5PJZ|rcsb pdb:5PK0|rcsb pdb:5PK1|rcsb pdb:5PK2|rcsb pdb:5PJU|rcsb pdb:5PK3|rcsb pdb:5PK4|rcsb pdb:5PK5|rcsb pdb:5PK6|rcsb pdb:5PK7|rcsb pdb:5PK8|rcsb pdb:5PK9|rcsb pdb:5PKA|rcsb pdb:5PKB|rcsb pdb:5PKC|rcsb pdb:5PKD|rcsb pdb:5PKE|rcsb pdb:5PKF|rcsb pdb:5PKG|rcsb pdb:5PKH|rcsb pdb:5PKI|rcsb pdb:5PKJ|rcsb pdb:5PKK|rcsb pdb:5PKL|rcsb pdb:5PKM|rcsb pdb:5PKN|rcsb pdb:5PKO|rcsb pdb:5PKP|rcsb pdb:5PKQ|rcsb pdb:5PKR|rcsb pdb:5PKS|rcsb pdb:5PKT|rcsb pdb:5PKU|rcsb pdb:5PKV|rcsb pdb:5PKW|rcsb pdb:5PKX|rcsb pdb:5PKY|rcsb pdb:5PKZ|rcsb pdb:5PL0|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072562"(blood microparticle)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|mint:Q6B0I6|rcsb pdb:3DXT|rcsb pdb:3DXU|rcsb pdb:4D6Q|rcsb pdb:4D6R|rcsb pdb:4D6S|rcsb pdb:4HON|rcsb pdb:5PL2|rcsb pdb:5PL3|rcsb pdb:5PL1|rcsb pdb:5PL4|rcsb pdb:5PL5|rcsb pdb:5PL6|rcsb pdb:5PL7|rcsb pdb:5PL8|rcsb pdb:5PL9|rcsb pdb:5PLA|rcsb pdb:5PLB|rcsb pdb:5PLC|rcsb pdb:5PLD|rcsb pdb:5PLE|rcsb pdb:5PLF|rcsb pdb:5PLG|rcsb pdb:5PLH|rcsb pdb:5PLI|rcsb pdb:5PLJ|rcsb pdb:5PLK|rcsb pdb:5PLL|rcsb pdb:5PLM|rcsb pdb:5PLN|rcsb pdb:5PLO|rcsb pdb:5PLP|rcsb pdb:5PLQ|rcsb pdb:5PLR|rcsb pdb:5PLS|rcsb pdb:5F5A|rcsb pdb:5F5C|rcsb pdb:5FP4|rcsb pdb:5FP7|rcsb pdb:5FP8|rcsb pdb:5FP9|rcsb pdb:5FPA|rcsb pdb:5FPB|rcsb pdb:5PH0|rcsb pdb:5PH1|rcsb pdb:5PH2|rcsb pdb:5PH3|rcsb pdb:5PH4|rcsb pdb:4HOO|rcsb pdb:5PH5|rcsb pdb:5PH6|rcsb pdb:5PH7|rcsb pdb:5PH8|rcsb pdb:5PH9|rcsb pdb:5PHA|rcsb pdb:5PHB|rcsb pdb:5PHC|rcsb pdb:5PHD|rcsb pdb:5PHE|rcsb pdb:5PLU|rcsb pdb:5PLV|rcsb pdb:5PLW|rcsb pdb:5PLX|rcsb pdb:5PLY|rcsb pdb:5PLZ|rcsb pdb:5PM0|rcsb pdb:5PM1|rcsb pdb:5PM2|rcsb pdb:5PM3|rcsb pdb:5PM4|rcsb pdb:5PM5|rcsb pdb:5PM6|rcsb pdb:5PM7|rcsb pdb:5PM8|rcsb pdb:5PM9|rcsb pdb:5PMA|rcsb pdb:5PMB|rcsb pdb:5PMC|rcsb pdb:5PMD|rcsb pdb:5PME|rcsb pdb:5PMF|rcsb pdb:5PMG|rcsb pdb:5PMH|rcsb pdb:5PMI|rcsb pdb:5PMJ|rcsb pdb:5PMK|rcsb pdb:5PML|rcsb pdb:5PMM|rcsb pdb:5PMN|rcsb pdb:5PMO|rcsb pdb:5PMP|rcsb pdb:5PMQ|rcsb pdb:5PMR|rcsb pdb:5PMS|rcsb pdb:5PMT|rcsb pdb:5PMU|rcsb pdb:5PMV|rcsb pdb:5PMW|rcsb pdb:5PMX|rcsb pdb:5PMY|rcsb pdb:5PMZ|rcsb pdb:5PN0|rcsb pdb:5PN1|rcsb pdb:5PN2|rcsb pdb:5PN3|rcsb pdb:5PN4|rcsb pdb:5PN5|rcsb pdb:5PN6|rcsb pdb:5PN7|rcsb pdb:5PN8|rcsb pdb:5PN9|rcsb pdb:5PNA|rcsb pdb:5PNB|rcsb pdb:5PNC|rcsb pdb:5PND|rcsb pdb:5PNE|rcsb pdb:5PNF|rcsb pdb:5PNG|rcsb pdb:5PNH|rcsb pdb:5PNI|rcsb pdb:5PNJ|rcsb pdb:5PNK|rcsb pdb:5PNL|rcsb pdb:5PNM|rcsb pdb:5PLT|rcsb pdb:5PNN|rcsb pdb:5PNO|rcsb pdb:5PNP|rcsb pdb:5PNQ|rcsb pdb:5PNR|rcsb pdb:5PNS|rcsb pdb:5PNU|rcsb pdb:5PNV|rcsb pdb:5PNW|rcsb pdb:6ETE|rcsb pdb:6ETG|rcsb pdb:6ETS|rcsb pdb:5PHJ|rcsb pdb:5PHK|rcsb pdb:5PHL|rcsb pdb:5PHM|rcsb pdb:5PHN|rcsb pdb:5PHO|rcsb pdb:5PHP|rcsb pdb:5PHQ|rcsb pdb:5PHR|rcsb pdb:5PHS|rcsb pdb:5PHT|rcsb pdb:5PHU|rcsb pdb:5PHV|rcsb pdb:5PHF|rcsb pdb:5PHG|rcsb pdb:5PHH|rcsb pdb:5PHI|rcsb pdb:5PHW|rcsb pdb:5PHX|rcsb pdb:5PHY|rcsb pdb:5PHZ|rcsb pdb:5PI0|rcsb pdb:5PI1|rcsb pdb:5PI2|rcsb pdb:5PI3|rcsb pdb:5PI4|dip:DIP-29606N refseq:NP_005757.1|refseq:NP_001273768.1|refseq:NP_001001715.2|refseq:XP_016875801.1|ensembl:ENSG00000152767(gene)|ensembl:ENST00000319562(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007416"(synapse assembly)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0030175"(filopodium)|go:"GO:0030425"(dendrite)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|go:"GO:0098942"(retrograde trans-synaptic signaling by trans-synaptic protein complex)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1905606"(regulation of presynapse assembly)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035899|interpro:IPR035963|interpro:IPR041788|mint:Q9Y4F1|rcsb pdb:4H6Y|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9035034 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:svQfKWBCSAPSGFAV5YPZXFvcqkk9606 rogid:EFAIqKR/G9qOxNYCZqkJDSqU+TU9606 rigid:7fqj2Gju3X4HbV0gQNAzWx9cUhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6B0I6 uniprotkb:Q9BWJ5 intact:EBI-4311651|uniprotkb:Q9NW76|uniprotkb:B3KPC4|uniprotkb:Q9NT41|uniprotkb:Q0VF39|ensembl:ENSP00000334181|ensembl:ENSP00000460897|ensembl:ENSP00000482224 intact:EBI-2555428|uniprotkb:Q7RTV1|uniprotkb:B2R568|ensembl:ENSP00000356541 psi-mi:kdm4d_human(display_long)|uniprotkb:KDM4D(gene name)|psi-mi:KDM4D(display_short)|uniprotkb:JHDM3D(gene name synonym)|uniprotkb:JMJD2D(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3D(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2D(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4D"(gene name synonym) psi-mi:sf3b5_human(display_long)|uniprotkb:SF3B10(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 10 kDa subunit(gene name synonym)|uniprotkb:SF3B5(gene name)|psi-mi:SF3B5(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480104|imex:IM-26985-481 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060509.2|rcsb pdb:5PI6|rcsb pdb:5PI7|rcsb pdb:5PI8|rcsb pdb:5PI9|rcsb pdb:5PIA|rcsb pdb:5PIB|rcsb pdb:5PIC|rcsb pdb:5PID|rcsb pdb:5PIE|rcsb pdb:5PIF|rcsb pdb:5PIG|rcsb pdb:5PIH|rcsb pdb:5PII|rcsb pdb:5PIJ|rcsb pdb:5PIK|rcsb pdb:5PIL|rcsb pdb:5PIM|rcsb pdb:5PIN|rcsb pdb:5PIO|rcsb pdb:5PIP|rcsb pdb:5PIQ|rcsb pdb:5PIR|rcsb pdb:5PIS|rcsb pdb:5PIT|rcsb pdb:5PIU|rcsb pdb:5PIV|rcsb pdb:5PIW|rcsb pdb:5PIX|rcsb pdb:5PIY|rcsb pdb:5PIZ|rcsb pdb:5PJ0|rcsb pdb:5PI5|rcsb pdb:5PJ1|rcsb pdb:5PJ2|rcsb pdb:5PJ3|rcsb pdb:5PJ4|rcsb pdb:5PJ6|rcsb pdb:5PJ7|rcsb pdb:5PJ8|rcsb pdb:5PJ9|rcsb pdb:5PJA|rcsb pdb:5PJB|rcsb pdb:5PJC|rcsb pdb:5PJD|rcsb pdb:5PJE|rcsb pdb:5PJF|rcsb pdb:5PJG|rcsb pdb:5PJ5|rcsb pdb:5PJH|rcsb pdb:5PJI|rcsb pdb:5PJJ|rcsb pdb:5PJK|rcsb pdb:5PJL|rcsb pdb:5PJM|rcsb pdb:5PJN|rcsb pdb:5PJO|rcsb pdb:5PJP|rcsb pdb:5PJQ|rcsb pdb:5PJR|rcsb pdb:5PJS|rcsb pdb:6ETT|rcsb pdb:6ETU|rcsb pdb:5PJT|rcsb pdb:6ETV|rcsb pdb:6ETW|rcsb pdb:6F5Q|rcsb pdb:6F5R|rcsb pdb:6F5S|rcsb pdb:6F5T|rcsb pdb:6H0W|rcsb pdb:6H0X|rcsb pdb:6H0Y|rcsb pdb:6H0Z|rcsb pdb:6H10|rcsb pdb:6H11|reactome:R-HSA-3214842|ensembl:ENSG00000186280(gene)|ensembl:ENST00000335080(transcript)|ensembl:ENST00000536741(transcript)|ensembl:ENST00000610872(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|rcsb pdb:5PJV|rcsb pdb:5PJW|rcsb pdb:5PJX|rcsb pdb:5PJY|rcsb pdb:5PJZ|rcsb pdb:5PK0|rcsb pdb:5PK1|rcsb pdb:5PK2|rcsb pdb:5PJU|rcsb pdb:5PK3|rcsb pdb:5PK4|rcsb pdb:5PK5|rcsb pdb:5PK6|rcsb pdb:5PK7|rcsb pdb:5PK8|rcsb pdb:5PK9|rcsb pdb:5PKA|rcsb pdb:5PKB|rcsb pdb:5PKC|rcsb pdb:5PKD|rcsb pdb:5PKE|rcsb pdb:5PKF|rcsb pdb:5PKG|rcsb pdb:5PKH|rcsb pdb:5PKI|rcsb pdb:5PKJ|rcsb pdb:5PKK|rcsb pdb:5PKL|rcsb pdb:5PKM|rcsb pdb:5PKN|rcsb pdb:5PKO|rcsb pdb:5PKP|rcsb pdb:5PKQ|rcsb pdb:5PKR|rcsb pdb:5PKS|rcsb pdb:5PKT|rcsb pdb:5PKU|rcsb pdb:5PKV|rcsb pdb:5PKW|rcsb pdb:5PKX|rcsb pdb:5PKY|rcsb pdb:5PKZ|rcsb pdb:5PL0|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072562"(blood microparticle)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|mint:Q6B0I6|rcsb pdb:3DXT|rcsb pdb:3DXU|rcsb pdb:4D6Q|rcsb pdb:4D6R|rcsb pdb:4D6S|rcsb pdb:4HON|rcsb pdb:5PL2|rcsb pdb:5PL3|rcsb pdb:5PL1|rcsb pdb:5PL4|rcsb pdb:5PL5|rcsb pdb:5PL6|rcsb pdb:5PL7|rcsb pdb:5PL8|rcsb pdb:5PL9|rcsb pdb:5PLA|rcsb pdb:5PLB|rcsb pdb:5PLC|rcsb pdb:5PLD|rcsb pdb:5PLE|rcsb pdb:5PLF|rcsb pdb:5PLG|rcsb pdb:5PLH|rcsb pdb:5PLI|rcsb pdb:5PLJ|rcsb pdb:5PLK|rcsb pdb:5PLL|rcsb pdb:5PLM|rcsb pdb:5PLN|rcsb pdb:5PLO|rcsb pdb:5PLP|rcsb pdb:5PLQ|rcsb pdb:5PLR|rcsb pdb:5PLS|rcsb pdb:5F5A|rcsb pdb:5F5C|rcsb pdb:5FP4|rcsb pdb:5FP7|rcsb pdb:5FP8|rcsb pdb:5FP9|rcsb pdb:5FPA|rcsb pdb:5FPB|rcsb pdb:5PH0|rcsb pdb:5PH1|rcsb pdb:5PH2|rcsb pdb:5PH3|rcsb pdb:5PH4|rcsb pdb:4HOO|rcsb pdb:5PH5|rcsb pdb:5PH6|rcsb pdb:5PH7|rcsb pdb:5PH8|rcsb pdb:5PH9|rcsb pdb:5PHA|rcsb pdb:5PHB|rcsb pdb:5PHC|rcsb pdb:5PHD|rcsb pdb:5PHE|rcsb pdb:5PLU|rcsb pdb:5PLV|rcsb pdb:5PLW|rcsb pdb:5PLX|rcsb pdb:5PLY|rcsb pdb:5PLZ|rcsb pdb:5PM0|rcsb pdb:5PM1|rcsb pdb:5PM2|rcsb pdb:5PM3|rcsb pdb:5PM4|rcsb pdb:5PM5|rcsb pdb:5PM6|rcsb pdb:5PM7|rcsb pdb:5PM8|rcsb pdb:5PM9|rcsb pdb:5PMA|rcsb pdb:5PMB|rcsb pdb:5PMC|rcsb pdb:5PMD|rcsb pdb:5PME|rcsb pdb:5PMF|rcsb pdb:5PMG|rcsb pdb:5PMH|rcsb pdb:5PMI|rcsb pdb:5PMJ|rcsb pdb:5PMK|rcsb pdb:5PML|rcsb pdb:5PMM|rcsb pdb:5PMN|rcsb pdb:5PMO|rcsb pdb:5PMP|rcsb pdb:5PMQ|rcsb pdb:5PMR|rcsb pdb:5PMS|rcsb pdb:5PMT|rcsb pdb:5PMU|rcsb pdb:5PMV|rcsb pdb:5PMW|rcsb pdb:5PMX|rcsb pdb:5PMY|rcsb pdb:5PMZ|rcsb pdb:5PN0|rcsb pdb:5PN1|rcsb pdb:5PN2|rcsb pdb:5PN3|rcsb pdb:5PN4|rcsb pdb:5PN5|rcsb pdb:5PN6|rcsb pdb:5PN7|rcsb pdb:5PN8|rcsb pdb:5PN9|rcsb pdb:5PNA|rcsb pdb:5PNB|rcsb pdb:5PNC|rcsb pdb:5PND|rcsb pdb:5PNE|rcsb pdb:5PNF|rcsb pdb:5PNG|rcsb pdb:5PNH|rcsb pdb:5PNI|rcsb pdb:5PNJ|rcsb pdb:5PNK|rcsb pdb:5PNL|rcsb pdb:5PNM|rcsb pdb:5PLT|rcsb pdb:5PNN|rcsb pdb:5PNO|rcsb pdb:5PNP|rcsb pdb:5PNQ|rcsb pdb:5PNR|rcsb pdb:5PNS|rcsb pdb:5PNU|rcsb pdb:5PNV|rcsb pdb:5PNW|rcsb pdb:6ETE|rcsb pdb:6ETG|rcsb pdb:6ETS|rcsb pdb:5PHJ|rcsb pdb:5PHK|rcsb pdb:5PHL|rcsb pdb:5PHM|rcsb pdb:5PHN|rcsb pdb:5PHO|rcsb pdb:5PHP|rcsb pdb:5PHQ|rcsb pdb:5PHR|rcsb pdb:5PHS|rcsb pdb:5PHT|rcsb pdb:5PHU|rcsb pdb:5PHV|rcsb pdb:5PHF|rcsb pdb:5PHG|rcsb pdb:5PHH|rcsb pdb:5PHI|rcsb pdb:5PHW|rcsb pdb:5PHX|rcsb pdb:5PHY|rcsb pdb:5PHZ|rcsb pdb:5PI0|rcsb pdb:5PI1|rcsb pdb:5PI2|rcsb pdb:5PI3|rcsb pdb:5PI4|dip:DIP-29606N refseq:NP_112577.1|ensembl:ENSG00000169976(gene)|ensembl:ENST00000367569(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR009846(Splicing factor 3B subunit 5/RDS3 complex subunit 10)|interpro:IPR017089(Splicing factor 3B, subunit 5)|mint:Q9BWJ5|rcsb pdb:5IFE|rcsb pdb:5O9Z|rcsb pdb:5Z56|rcsb pdb:5Z58|rcsb pdb:5ZYA|rcsb pdb:6AH0|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|rcsb pdb:5Z57 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:svQfKWBCSAPSGFAV5YPZXFvcqkk9606 rogid:wuQBsSytGhSg64IQSmEJXe+26zQ9606 rigid:7fqj2Gju3X4HbV0gQNAzWx9cUhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6B0I6 uniprotkb:O14967 intact:EBI-4311651|uniprotkb:Q9NW76|uniprotkb:B3KPC4|uniprotkb:Q9NT41|uniprotkb:Q0VF39|ensembl:ENSP00000334181|ensembl:ENSP00000460897|ensembl:ENSP00000482224 intact:EBI-3907005|uniprotkb:D3DNY8|uniprotkb:B3KS90|uniprotkb:B4DXV8|ensembl:ENSP00000326699|ensembl:ENSP00000392782 psi-mi:kdm4d_human(display_long)|uniprotkb:KDM4D(gene name)|psi-mi:KDM4D(display_short)|uniprotkb:JHDM3D(gene name synonym)|uniprotkb:JMJD2D(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3D(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2D(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4D"(gene name synonym) psi-mi:clgn_human(display_long)|uniprotkb:CLGN(gene name)|psi-mi:CLGN(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480104|imex:IM-26985-481 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060509.2|rcsb pdb:5PI6|rcsb pdb:5PI7|rcsb pdb:5PI8|rcsb pdb:5PI9|rcsb pdb:5PIA|rcsb pdb:5PIB|rcsb pdb:5PIC|rcsb pdb:5PID|rcsb pdb:5PIE|rcsb pdb:5PIF|rcsb pdb:5PIG|rcsb pdb:5PIH|rcsb pdb:5PII|rcsb pdb:5PIJ|rcsb pdb:5PIK|rcsb pdb:5PIL|rcsb pdb:5PIM|rcsb pdb:5PIN|rcsb pdb:5PIO|rcsb pdb:5PIP|rcsb pdb:5PIQ|rcsb pdb:5PIR|rcsb pdb:5PIS|rcsb pdb:5PIT|rcsb pdb:5PIU|rcsb pdb:5PIV|rcsb pdb:5PIW|rcsb pdb:5PIX|rcsb pdb:5PIY|rcsb pdb:5PIZ|rcsb pdb:5PJ0|rcsb pdb:5PI5|rcsb pdb:5PJ1|rcsb pdb:5PJ2|rcsb pdb:5PJ3|rcsb pdb:5PJ4|rcsb pdb:5PJ6|rcsb pdb:5PJ7|rcsb pdb:5PJ8|rcsb pdb:5PJ9|rcsb pdb:5PJA|rcsb pdb:5PJB|rcsb pdb:5PJC|rcsb pdb:5PJD|rcsb pdb:5PJE|rcsb pdb:5PJF|rcsb pdb:5PJG|rcsb pdb:5PJ5|rcsb pdb:5PJH|rcsb pdb:5PJI|rcsb pdb:5PJJ|rcsb pdb:5PJK|rcsb pdb:5PJL|rcsb pdb:5PJM|rcsb pdb:5PJN|rcsb pdb:5PJO|rcsb pdb:5PJP|rcsb pdb:5PJQ|rcsb pdb:5PJR|rcsb pdb:5PJS|rcsb pdb:6ETT|rcsb pdb:6ETU|rcsb pdb:5PJT|rcsb pdb:6ETV|rcsb pdb:6ETW|rcsb pdb:6F5Q|rcsb pdb:6F5R|rcsb pdb:6F5S|rcsb pdb:6F5T|rcsb pdb:6H0W|rcsb pdb:6H0X|rcsb pdb:6H0Y|rcsb pdb:6H0Z|rcsb pdb:6H10|rcsb pdb:6H11|reactome:R-HSA-3214842|ensembl:ENSG00000186280(gene)|ensembl:ENST00000335080(transcript)|ensembl:ENST00000536741(transcript)|ensembl:ENST00000610872(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|rcsb pdb:5PJV|rcsb pdb:5PJW|rcsb pdb:5PJX|rcsb pdb:5PJY|rcsb pdb:5PJZ|rcsb pdb:5PK0|rcsb pdb:5PK1|rcsb pdb:5PK2|rcsb pdb:5PJU|rcsb pdb:5PK3|rcsb pdb:5PK4|rcsb pdb:5PK5|rcsb pdb:5PK6|rcsb pdb:5PK7|rcsb pdb:5PK8|rcsb pdb:5PK9|rcsb pdb:5PKA|rcsb pdb:5PKB|rcsb pdb:5PKC|rcsb pdb:5PKD|rcsb pdb:5PKE|rcsb pdb:5PKF|rcsb pdb:5PKG|rcsb pdb:5PKH|rcsb pdb:5PKI|rcsb pdb:5PKJ|rcsb pdb:5PKK|rcsb pdb:5PKL|rcsb pdb:5PKM|rcsb pdb:5PKN|rcsb pdb:5PKO|rcsb pdb:5PKP|rcsb pdb:5PKQ|rcsb pdb:5PKR|rcsb pdb:5PKS|rcsb pdb:5PKT|rcsb pdb:5PKU|rcsb pdb:5PKV|rcsb pdb:5PKW|rcsb pdb:5PKX|rcsb pdb:5PKY|rcsb pdb:5PKZ|rcsb pdb:5PL0|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072562"(blood microparticle)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|mint:Q6B0I6|rcsb pdb:3DXT|rcsb pdb:3DXU|rcsb pdb:4D6Q|rcsb pdb:4D6R|rcsb pdb:4D6S|rcsb pdb:4HON|rcsb pdb:5PL2|rcsb pdb:5PL3|rcsb pdb:5PL1|rcsb pdb:5PL4|rcsb pdb:5PL5|rcsb pdb:5PL6|rcsb pdb:5PL7|rcsb pdb:5PL8|rcsb pdb:5PL9|rcsb pdb:5PLA|rcsb pdb:5PLB|rcsb pdb:5PLC|rcsb pdb:5PLD|rcsb pdb:5PLE|rcsb pdb:5PLF|rcsb pdb:5PLG|rcsb pdb:5PLH|rcsb pdb:5PLI|rcsb pdb:5PLJ|rcsb pdb:5PLK|rcsb pdb:5PLL|rcsb pdb:5PLM|rcsb pdb:5PLN|rcsb pdb:5PLO|rcsb pdb:5PLP|rcsb pdb:5PLQ|rcsb pdb:5PLR|rcsb pdb:5PLS|rcsb pdb:5F5A|rcsb pdb:5F5C|rcsb pdb:5FP4|rcsb pdb:5FP7|rcsb pdb:5FP8|rcsb pdb:5FP9|rcsb pdb:5FPA|rcsb pdb:5FPB|rcsb pdb:5PH0|rcsb pdb:5PH1|rcsb pdb:5PH2|rcsb pdb:5PH3|rcsb pdb:5PH4|rcsb pdb:4HOO|rcsb pdb:5PH5|rcsb pdb:5PH6|rcsb pdb:5PH7|rcsb pdb:5PH8|rcsb pdb:5PH9|rcsb pdb:5PHA|rcsb pdb:5PHB|rcsb pdb:5PHC|rcsb pdb:5PHD|rcsb pdb:5PHE|rcsb pdb:5PLU|rcsb pdb:5PLV|rcsb pdb:5PLW|rcsb pdb:5PLX|rcsb pdb:5PLY|rcsb pdb:5PLZ|rcsb pdb:5PM0|rcsb pdb:5PM1|rcsb pdb:5PM2|rcsb pdb:5PM3|rcsb pdb:5PM4|rcsb pdb:5PM5|rcsb pdb:5PM6|rcsb pdb:5PM7|rcsb pdb:5PM8|rcsb pdb:5PM9|rcsb pdb:5PMA|rcsb pdb:5PMB|rcsb pdb:5PMC|rcsb pdb:5PMD|rcsb pdb:5PME|rcsb pdb:5PMF|rcsb pdb:5PMG|rcsb pdb:5PMH|rcsb pdb:5PMI|rcsb pdb:5PMJ|rcsb pdb:5PMK|rcsb pdb:5PML|rcsb pdb:5PMM|rcsb pdb:5PMN|rcsb pdb:5PMO|rcsb pdb:5PMP|rcsb pdb:5PMQ|rcsb pdb:5PMR|rcsb pdb:5PMS|rcsb pdb:5PMT|rcsb pdb:5PMU|rcsb pdb:5PMV|rcsb pdb:5PMW|rcsb pdb:5PMX|rcsb pdb:5PMY|rcsb pdb:5PMZ|rcsb pdb:5PN0|rcsb pdb:5PN1|rcsb pdb:5PN2|rcsb pdb:5PN3|rcsb pdb:5PN4|rcsb pdb:5PN5|rcsb pdb:5PN6|rcsb pdb:5PN7|rcsb pdb:5PN8|rcsb pdb:5PN9|rcsb pdb:5PNA|rcsb pdb:5PNB|rcsb pdb:5PNC|rcsb pdb:5PND|rcsb pdb:5PNE|rcsb pdb:5PNF|rcsb pdb:5PNG|rcsb pdb:5PNH|rcsb pdb:5PNI|rcsb pdb:5PNJ|rcsb pdb:5PNK|rcsb pdb:5PNL|rcsb pdb:5PNM|rcsb pdb:5PLT|rcsb pdb:5PNN|rcsb pdb:5PNO|rcsb pdb:5PNP|rcsb pdb:5PNQ|rcsb pdb:5PNR|rcsb pdb:5PNS|rcsb pdb:5PNU|rcsb pdb:5PNV|rcsb pdb:5PNW|rcsb pdb:6ETE|rcsb pdb:6ETG|rcsb pdb:6ETS|rcsb pdb:5PHJ|rcsb pdb:5PHK|rcsb pdb:5PHL|rcsb pdb:5PHM|rcsb pdb:5PHN|rcsb pdb:5PHO|rcsb pdb:5PHP|rcsb pdb:5PHQ|rcsb pdb:5PHR|rcsb pdb:5PHS|rcsb pdb:5PHT|rcsb pdb:5PHU|rcsb pdb:5PHV|rcsb pdb:5PHF|rcsb pdb:5PHG|rcsb pdb:5PHH|rcsb pdb:5PHI|rcsb pdb:5PHW|rcsb pdb:5PHX|rcsb pdb:5PHY|rcsb pdb:5PHZ|rcsb pdb:5PI0|rcsb pdb:5PI1|rcsb pdb:5PI2|rcsb pdb:5PI3|rcsb pdb:5PI4|dip:DIP-29606N refseq:NP_001124147.1|refseq:NP_004353.1|ensembl:ENSG00000153132(gene)|ensembl:ENST00000325617(transcript)|ensembl:ENST00000414773(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007338"(single fertilization)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:O14967 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:svQfKWBCSAPSGFAV5YPZXFvcqkk9606 rogid:Akb2XoiNjob34njC2erE11yg80w9606 rigid:7fqj2Gju3X4HbV0gQNAzWx9cUhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6B0I6 uniprotkb:Q15459 intact:EBI-4311651|uniprotkb:Q9NW76|uniprotkb:B3KPC4|uniprotkb:Q9NT41|uniprotkb:Q0VF39|ensembl:ENSP00000334181|ensembl:ENSP00000460897|ensembl:ENSP00000482224 intact:EBI-1054743|uniprotkb:E9PAW1|ensembl:ENSP00000215793 psi-mi:kdm4d_human(display_long)|uniprotkb:KDM4D(gene name)|psi-mi:KDM4D(display_short)|uniprotkb:JHDM3D(gene name synonym)|uniprotkb:JMJD2D(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3D(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2D(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4D"(gene name synonym) psi-mi:sf3a1_human(display_long)|uniprotkb:Spliceosome-associated protein 114(gene name synonym)|uniprotkb:SF3a120(gene name synonym)|uniprotkb:SF3A1(gene name)|psi-mi:SF3A1(display_short)|uniprotkb:SAP114(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480104|imex:IM-26985-481 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060509.2|rcsb pdb:5PI6|rcsb pdb:5PI7|rcsb pdb:5PI8|rcsb pdb:5PI9|rcsb pdb:5PIA|rcsb pdb:5PIB|rcsb pdb:5PIC|rcsb pdb:5PID|rcsb pdb:5PIE|rcsb pdb:5PIF|rcsb pdb:5PIG|rcsb pdb:5PIH|rcsb pdb:5PII|rcsb pdb:5PIJ|rcsb pdb:5PIK|rcsb pdb:5PIL|rcsb pdb:5PIM|rcsb pdb:5PIN|rcsb pdb:5PIO|rcsb pdb:5PIP|rcsb pdb:5PIQ|rcsb pdb:5PIR|rcsb pdb:5PIS|rcsb pdb:5PIT|rcsb pdb:5PIU|rcsb pdb:5PIV|rcsb pdb:5PIW|rcsb pdb:5PIX|rcsb pdb:5PIY|rcsb pdb:5PIZ|rcsb pdb:5PJ0|rcsb pdb:5PI5|rcsb pdb:5PJ1|rcsb pdb:5PJ2|rcsb pdb:5PJ3|rcsb pdb:5PJ4|rcsb pdb:5PJ6|rcsb pdb:5PJ7|rcsb pdb:5PJ8|rcsb pdb:5PJ9|rcsb pdb:5PJA|rcsb pdb:5PJB|rcsb pdb:5PJC|rcsb pdb:5PJD|rcsb pdb:5PJE|rcsb pdb:5PJF|rcsb pdb:5PJG|rcsb pdb:5PJ5|rcsb pdb:5PJH|rcsb pdb:5PJI|rcsb pdb:5PJJ|rcsb pdb:5PJK|rcsb pdb:5PJL|rcsb pdb:5PJM|rcsb pdb:5PJN|rcsb pdb:5PJO|rcsb pdb:5PJP|rcsb pdb:5PJQ|rcsb pdb:5PJR|rcsb pdb:5PJS|rcsb pdb:6ETT|rcsb pdb:6ETU|rcsb pdb:5PJT|rcsb pdb:6ETV|rcsb pdb:6ETW|rcsb pdb:6F5Q|rcsb pdb:6F5R|rcsb pdb:6F5S|rcsb pdb:6F5T|rcsb pdb:6H0W|rcsb pdb:6H0X|rcsb pdb:6H0Y|rcsb pdb:6H0Z|rcsb pdb:6H10|rcsb pdb:6H11|reactome:R-HSA-3214842|ensembl:ENSG00000186280(gene)|ensembl:ENST00000335080(transcript)|ensembl:ENST00000536741(transcript)|ensembl:ENST00000610872(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|rcsb pdb:5PJV|rcsb pdb:5PJW|rcsb pdb:5PJX|rcsb pdb:5PJY|rcsb pdb:5PJZ|rcsb pdb:5PK0|rcsb pdb:5PK1|rcsb pdb:5PK2|rcsb pdb:5PJU|rcsb pdb:5PK3|rcsb pdb:5PK4|rcsb pdb:5PK5|rcsb pdb:5PK6|rcsb pdb:5PK7|rcsb pdb:5PK8|rcsb pdb:5PK9|rcsb pdb:5PKA|rcsb pdb:5PKB|rcsb pdb:5PKC|rcsb pdb:5PKD|rcsb pdb:5PKE|rcsb pdb:5PKF|rcsb pdb:5PKG|rcsb pdb:5PKH|rcsb pdb:5PKI|rcsb pdb:5PKJ|rcsb pdb:5PKK|rcsb pdb:5PKL|rcsb pdb:5PKM|rcsb pdb:5PKN|rcsb pdb:5PKO|rcsb pdb:5PKP|rcsb pdb:5PKQ|rcsb pdb:5PKR|rcsb pdb:5PKS|rcsb pdb:5PKT|rcsb pdb:5PKU|rcsb pdb:5PKV|rcsb pdb:5PKW|rcsb pdb:5PKX|rcsb pdb:5PKY|rcsb pdb:5PKZ|rcsb pdb:5PL0|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072562"(blood microparticle)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|mint:Q6B0I6|rcsb pdb:3DXT|rcsb pdb:3DXU|rcsb pdb:4D6Q|rcsb pdb:4D6R|rcsb pdb:4D6S|rcsb pdb:4HON|rcsb pdb:5PL2|rcsb pdb:5PL3|rcsb pdb:5PL1|rcsb pdb:5PL4|rcsb pdb:5PL5|rcsb pdb:5PL6|rcsb pdb:5PL7|rcsb pdb:5PL8|rcsb pdb:5PL9|rcsb pdb:5PLA|rcsb pdb:5PLB|rcsb pdb:5PLC|rcsb pdb:5PLD|rcsb pdb:5PLE|rcsb pdb:5PLF|rcsb pdb:5PLG|rcsb pdb:5PLH|rcsb pdb:5PLI|rcsb pdb:5PLJ|rcsb pdb:5PLK|rcsb pdb:5PLL|rcsb pdb:5PLM|rcsb pdb:5PLN|rcsb pdb:5PLO|rcsb pdb:5PLP|rcsb pdb:5PLQ|rcsb pdb:5PLR|rcsb pdb:5PLS|rcsb pdb:5F5A|rcsb pdb:5F5C|rcsb pdb:5FP4|rcsb pdb:5FP7|rcsb pdb:5FP8|rcsb pdb:5FP9|rcsb pdb:5FPA|rcsb pdb:5FPB|rcsb pdb:5PH0|rcsb pdb:5PH1|rcsb pdb:5PH2|rcsb pdb:5PH3|rcsb pdb:5PH4|rcsb pdb:4HOO|rcsb pdb:5PH5|rcsb pdb:5PH6|rcsb pdb:5PH7|rcsb pdb:5PH8|rcsb pdb:5PH9|rcsb pdb:5PHA|rcsb pdb:5PHB|rcsb pdb:5PHC|rcsb pdb:5PHD|rcsb pdb:5PHE|rcsb pdb:5PLU|rcsb pdb:5PLV|rcsb pdb:5PLW|rcsb pdb:5PLX|rcsb pdb:5PLY|rcsb pdb:5PLZ|rcsb pdb:5PM0|rcsb pdb:5PM1|rcsb pdb:5PM2|rcsb pdb:5PM3|rcsb pdb:5PM4|rcsb pdb:5PM5|rcsb pdb:5PM6|rcsb pdb:5PM7|rcsb pdb:5PM8|rcsb pdb:5PM9|rcsb pdb:5PMA|rcsb pdb:5PMB|rcsb pdb:5PMC|rcsb pdb:5PMD|rcsb pdb:5PME|rcsb pdb:5PMF|rcsb pdb:5PMG|rcsb pdb:5PMH|rcsb pdb:5PMI|rcsb pdb:5PMJ|rcsb pdb:5PMK|rcsb pdb:5PML|rcsb pdb:5PMM|rcsb pdb:5PMN|rcsb pdb:5PMO|rcsb pdb:5PMP|rcsb pdb:5PMQ|rcsb pdb:5PMR|rcsb pdb:5PMS|rcsb pdb:5PMT|rcsb pdb:5PMU|rcsb pdb:5PMV|rcsb pdb:5PMW|rcsb pdb:5PMX|rcsb pdb:5PMY|rcsb pdb:5PMZ|rcsb pdb:5PN0|rcsb pdb:5PN1|rcsb pdb:5PN2|rcsb pdb:5PN3|rcsb pdb:5PN4|rcsb pdb:5PN5|rcsb pdb:5PN6|rcsb pdb:5PN7|rcsb pdb:5PN8|rcsb pdb:5PN9|rcsb pdb:5PNA|rcsb pdb:5PNB|rcsb pdb:5PNC|rcsb pdb:5PND|rcsb pdb:5PNE|rcsb pdb:5PNF|rcsb pdb:5PNG|rcsb pdb:5PNH|rcsb pdb:5PNI|rcsb pdb:5PNJ|rcsb pdb:5PNK|rcsb pdb:5PNL|rcsb pdb:5PNM|rcsb pdb:5PLT|rcsb pdb:5PNN|rcsb pdb:5PNO|rcsb pdb:5PNP|rcsb pdb:5PNQ|rcsb pdb:5PNR|rcsb pdb:5PNS|rcsb pdb:5PNU|rcsb pdb:5PNV|rcsb pdb:5PNW|rcsb pdb:6ETE|rcsb pdb:6ETG|rcsb pdb:6ETS|rcsb pdb:5PHJ|rcsb pdb:5PHK|rcsb pdb:5PHL|rcsb pdb:5PHM|rcsb pdb:5PHN|rcsb pdb:5PHO|rcsb pdb:5PHP|rcsb pdb:5PHQ|rcsb pdb:5PHR|rcsb pdb:5PHS|rcsb pdb:5PHT|rcsb pdb:5PHU|rcsb pdb:5PHV|rcsb pdb:5PHF|rcsb pdb:5PHG|rcsb pdb:5PHH|rcsb pdb:5PHI|rcsb pdb:5PHW|rcsb pdb:5PHX|rcsb pdb:5PHY|rcsb pdb:5PHZ|rcsb pdb:5PI0|rcsb pdb:5PI1|rcsb pdb:5PI2|rcsb pdb:5PI3|rcsb pdb:5PI4|dip:DIP-29606N refseq:NP_005868.1|ensembl:ENSG00000099995(gene)|ensembl:ENST00000215793(transcript)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|rcsb pdb:2DT6|go:"GO:0071004"(U2-type prespliceosome)|rcsb pdb:2DT7|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6QX9|go:"GO:0071005"(U2-type precatalytic spliceosome)|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABI|reactome:R-HSA-72163|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1903241"(U2-type prespliceosome assembly)|interpro:IPR000061(SWAP/Surp)|interpro:IPR000626(Ubiquitin)|interpro:IPR022030|interpro:IPR029071|interpro:IPR035563|interpro:IPR035967|mint:Q15459|rcsb pdb:1ZKH|dip:DIP-29164N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:svQfKWBCSAPSGFAV5YPZXFvcqkk9606 rogid:YrIs3RwfjUcDsHCJDgTLMnOUJZM9606 rigid:7fqj2Gju3X4HbV0gQNAzWx9cUhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6B0I6 uniprotkb:P26583 intact:EBI-4311651|uniprotkb:Q9NW76|uniprotkb:B3KPC4|uniprotkb:Q9NT41|uniprotkb:Q0VF39|ensembl:ENSP00000334181|ensembl:ENSP00000460897|ensembl:ENSP00000482224 intact:EBI-1057009|uniprotkb:Q5U072|uniprotkb:D3DP37|uniprotkb:B2R4K8|ensembl:ENSP00000296503|ensembl:ENSP00000393448|ensembl:ENSP00000404912 psi-mi:kdm4d_human(display_long)|uniprotkb:KDM4D(gene name)|psi-mi:KDM4D(display_short)|uniprotkb:JHDM3D(gene name synonym)|uniprotkb:JMJD2D(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3D(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2D(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4D"(gene name synonym) psi-mi:hmgb2_human(display_long)|uniprotkb:HMGB2(gene name)|psi-mi:HMGB2(display_short)|uniprotkb:HMG2(gene name synonym)|uniprotkb:High mobility group protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480104|imex:IM-26985-481 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060509.2|rcsb pdb:5PI6|rcsb pdb:5PI7|rcsb pdb:5PI8|rcsb pdb:5PI9|rcsb pdb:5PIA|rcsb pdb:5PIB|rcsb pdb:5PIC|rcsb pdb:5PID|rcsb pdb:5PIE|rcsb pdb:5PIF|rcsb pdb:5PIG|rcsb pdb:5PIH|rcsb pdb:5PII|rcsb pdb:5PIJ|rcsb pdb:5PIK|rcsb pdb:5PIL|rcsb pdb:5PIM|rcsb pdb:5PIN|rcsb pdb:5PIO|rcsb pdb:5PIP|rcsb pdb:5PIQ|rcsb pdb:5PIR|rcsb pdb:5PIS|rcsb pdb:5PIT|rcsb pdb:5PIU|rcsb pdb:5PIV|rcsb pdb:5PIW|rcsb pdb:5PIX|rcsb pdb:5PIY|rcsb pdb:5PIZ|rcsb pdb:5PJ0|rcsb pdb:5PI5|rcsb pdb:5PJ1|rcsb pdb:5PJ2|rcsb pdb:5PJ3|rcsb pdb:5PJ4|rcsb pdb:5PJ6|rcsb pdb:5PJ7|rcsb pdb:5PJ8|rcsb pdb:5PJ9|rcsb pdb:5PJA|rcsb pdb:5PJB|rcsb pdb:5PJC|rcsb pdb:5PJD|rcsb pdb:5PJE|rcsb pdb:5PJF|rcsb pdb:5PJG|rcsb pdb:5PJ5|rcsb pdb:5PJH|rcsb pdb:5PJI|rcsb pdb:5PJJ|rcsb pdb:5PJK|rcsb pdb:5PJL|rcsb pdb:5PJM|rcsb pdb:5PJN|rcsb pdb:5PJO|rcsb pdb:5PJP|rcsb pdb:5PJQ|rcsb pdb:5PJR|rcsb pdb:5PJS|rcsb pdb:6ETT|rcsb pdb:6ETU|rcsb pdb:5PJT|rcsb pdb:6ETV|rcsb pdb:6ETW|rcsb pdb:6F5Q|rcsb pdb:6F5R|rcsb pdb:6F5S|rcsb pdb:6F5T|rcsb pdb:6H0W|rcsb pdb:6H0X|rcsb pdb:6H0Y|rcsb pdb:6H0Z|rcsb pdb:6H10|rcsb pdb:6H11|reactome:R-HSA-3214842|ensembl:ENSG00000186280(gene)|ensembl:ENST00000335080(transcript)|ensembl:ENST00000536741(transcript)|ensembl:ENST00000610872(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|rcsb pdb:5PJV|rcsb pdb:5PJW|rcsb pdb:5PJX|rcsb pdb:5PJY|rcsb pdb:5PJZ|rcsb pdb:5PK0|rcsb pdb:5PK1|rcsb pdb:5PK2|rcsb pdb:5PJU|rcsb pdb:5PK3|rcsb pdb:5PK4|rcsb pdb:5PK5|rcsb pdb:5PK6|rcsb pdb:5PK7|rcsb pdb:5PK8|rcsb pdb:5PK9|rcsb pdb:5PKA|rcsb pdb:5PKB|rcsb pdb:5PKC|rcsb pdb:5PKD|rcsb pdb:5PKE|rcsb pdb:5PKF|rcsb pdb:5PKG|rcsb pdb:5PKH|rcsb pdb:5PKI|rcsb pdb:5PKJ|rcsb pdb:5PKK|rcsb pdb:5PKL|rcsb pdb:5PKM|rcsb pdb:5PKN|rcsb pdb:5PKO|rcsb pdb:5PKP|rcsb pdb:5PKQ|rcsb pdb:5PKR|rcsb pdb:5PKS|rcsb pdb:5PKT|rcsb pdb:5PKU|rcsb pdb:5PKV|rcsb pdb:5PKW|rcsb pdb:5PKX|rcsb pdb:5PKY|rcsb pdb:5PKZ|rcsb pdb:5PL0|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072562"(blood microparticle)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|mint:Q6B0I6|rcsb pdb:3DXT|rcsb pdb:3DXU|rcsb pdb:4D6Q|rcsb pdb:4D6R|rcsb pdb:4D6S|rcsb pdb:4HON|rcsb pdb:5PL2|rcsb pdb:5PL3|rcsb pdb:5PL1|rcsb pdb:5PL4|rcsb pdb:5PL5|rcsb pdb:5PL6|rcsb pdb:5PL7|rcsb pdb:5PL8|rcsb pdb:5PL9|rcsb pdb:5PLA|rcsb pdb:5PLB|rcsb pdb:5PLC|rcsb pdb:5PLD|rcsb pdb:5PLE|rcsb pdb:5PLF|rcsb pdb:5PLG|rcsb pdb:5PLH|rcsb pdb:5PLI|rcsb pdb:5PLJ|rcsb pdb:5PLK|rcsb pdb:5PLL|rcsb pdb:5PLM|rcsb pdb:5PLN|rcsb pdb:5PLO|rcsb pdb:5PLP|rcsb pdb:5PLQ|rcsb pdb:5PLR|rcsb pdb:5PLS|rcsb pdb:5F5A|rcsb pdb:5F5C|rcsb pdb:5FP4|rcsb pdb:5FP7|rcsb pdb:5FP8|rcsb pdb:5FP9|rcsb pdb:5FPA|rcsb pdb:5FPB|rcsb pdb:5PH0|rcsb pdb:5PH1|rcsb pdb:5PH2|rcsb pdb:5PH3|rcsb pdb:5PH4|rcsb pdb:4HOO|rcsb pdb:5PH5|rcsb pdb:5PH6|rcsb pdb:5PH7|rcsb pdb:5PH8|rcsb pdb:5PH9|rcsb pdb:5PHA|rcsb pdb:5PHB|rcsb pdb:5PHC|rcsb pdb:5PHD|rcsb pdb:5PHE|rcsb pdb:5PLU|rcsb pdb:5PLV|rcsb pdb:5PLW|rcsb pdb:5PLX|rcsb pdb:5PLY|rcsb pdb:5PLZ|rcsb pdb:5PM0|rcsb pdb:5PM1|rcsb pdb:5PM2|rcsb pdb:5PM3|rcsb pdb:5PM4|rcsb pdb:5PM5|rcsb pdb:5PM6|rcsb pdb:5PM7|rcsb pdb:5PM8|rcsb pdb:5PM9|rcsb pdb:5PMA|rcsb pdb:5PMB|rcsb pdb:5PMC|rcsb pdb:5PMD|rcsb pdb:5PME|rcsb pdb:5PMF|rcsb pdb:5PMG|rcsb pdb:5PMH|rcsb pdb:5PMI|rcsb pdb:5PMJ|rcsb pdb:5PMK|rcsb pdb:5PML|rcsb pdb:5PMM|rcsb pdb:5PMN|rcsb pdb:5PMO|rcsb pdb:5PMP|rcsb pdb:5PMQ|rcsb pdb:5PMR|rcsb pdb:5PMS|rcsb pdb:5PMT|rcsb pdb:5PMU|rcsb pdb:5PMV|rcsb pdb:5PMW|rcsb pdb:5PMX|rcsb pdb:5PMY|rcsb pdb:5PMZ|rcsb pdb:5PN0|rcsb pdb:5PN1|rcsb pdb:5PN2|rcsb pdb:5PN3|rcsb pdb:5PN4|rcsb pdb:5PN5|rcsb pdb:5PN6|rcsb pdb:5PN7|rcsb pdb:5PN8|rcsb pdb:5PN9|rcsb pdb:5PNA|rcsb pdb:5PNB|rcsb pdb:5PNC|rcsb pdb:5PND|rcsb pdb:5PNE|rcsb pdb:5PNF|rcsb pdb:5PNG|rcsb pdb:5PNH|rcsb pdb:5PNI|rcsb pdb:5PNJ|rcsb pdb:5PNK|rcsb pdb:5PNL|rcsb pdb:5PNM|rcsb pdb:5PLT|rcsb pdb:5PNN|rcsb pdb:5PNO|rcsb pdb:5PNP|rcsb pdb:5PNQ|rcsb pdb:5PNR|rcsb pdb:5PNS|rcsb pdb:5PNU|rcsb pdb:5PNV|rcsb pdb:5PNW|rcsb pdb:6ETE|rcsb pdb:6ETG|rcsb pdb:6ETS|rcsb pdb:5PHJ|rcsb pdb:5PHK|rcsb pdb:5PHL|rcsb pdb:5PHM|rcsb pdb:5PHN|rcsb pdb:5PHO|rcsb pdb:5PHP|rcsb pdb:5PHQ|rcsb pdb:5PHR|rcsb pdb:5PHS|rcsb pdb:5PHT|rcsb pdb:5PHU|rcsb pdb:5PHV|rcsb pdb:5PHF|rcsb pdb:5PHG|rcsb pdb:5PHH|rcsb pdb:5PHI|rcsb pdb:5PHW|rcsb pdb:5PHX|rcsb pdb:5PHY|rcsb pdb:5PHZ|rcsb pdb:5PI0|rcsb pdb:5PI1|rcsb pdb:5PI2|rcsb pdb:5PI3|rcsb pdb:5PI4|dip:DIP-29606N refseq:NP_001124160.1|refseq:NP_001124161.1|refseq:NP_002120.1|ensembl:ENSG00000164104(gene)|ensembl:ENST00000296503(transcript)|ensembl:ENST00000438704(transcript)|ensembl:ENST00000446922(transcript)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006265"(DNA topological change)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006325"(chromatin organization)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032075"(positive regulation of nuclease activity)|go:"GO:0032392"(DNA geometric change)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033151"("V(D)J recombination")|go:"GO:0042056"(chemoattractant activity)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0044378"(non-sequence-specific DNA binding, bending)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045654"(positive regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0097100"(supercoiled DNA binding)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR017967|interpro:IPR036910|mint:P26583|reactome:R-HSA-140342 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:svQfKWBCSAPSGFAV5YPZXFvcqkk9606 rogid:ACzaSeIwT3vM4ZgpCSSlzA6nd4U9606 rigid:7fqj2Gju3X4HbV0gQNAzWx9cUhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6B0I6 uniprotkb:P05386 intact:EBI-4311651|uniprotkb:Q9NW76|uniprotkb:B3KPC4|uniprotkb:Q9NT41|uniprotkb:Q0VF39|ensembl:ENSP00000334181|ensembl:ENSP00000460897|ensembl:ENSP00000482224 intact:EBI-354582|uniprotkb:A6NIB2|ensembl:ENSP00000346037 psi-mi:kdm4d_human(display_long)|uniprotkb:KDM4D(gene name)|psi-mi:KDM4D(display_short)|uniprotkb:JHDM3D(gene name synonym)|uniprotkb:JMJD2D(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3D(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2D(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4D"(gene name synonym) psi-mi:rla1_human(display_long)|uniprotkb:RPLP1(gene name)|psi-mi:RPLP1(display_short)|uniprotkb:RRP1(gene name synonym)|uniprotkb:Large ribosomal subunit protein P1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480104|imex:IM-26985-481 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060509.2|rcsb pdb:5PI6|rcsb pdb:5PI7|rcsb pdb:5PI8|rcsb pdb:5PI9|rcsb pdb:5PIA|rcsb pdb:5PIB|rcsb pdb:5PIC|rcsb pdb:5PID|rcsb pdb:5PIE|rcsb pdb:5PIF|rcsb pdb:5PIG|rcsb pdb:5PIH|rcsb pdb:5PII|rcsb pdb:5PIJ|rcsb pdb:5PIK|rcsb pdb:5PIL|rcsb pdb:5PIM|rcsb pdb:5PIN|rcsb pdb:5PIO|rcsb pdb:5PIP|rcsb pdb:5PIQ|rcsb pdb:5PIR|rcsb pdb:5PIS|rcsb pdb:5PIT|rcsb pdb:5PIU|rcsb pdb:5PIV|rcsb pdb:5PIW|rcsb pdb:5PIX|rcsb pdb:5PIY|rcsb pdb:5PIZ|rcsb pdb:5PJ0|rcsb pdb:5PI5|rcsb pdb:5PJ1|rcsb pdb:5PJ2|rcsb pdb:5PJ3|rcsb pdb:5PJ4|rcsb pdb:5PJ6|rcsb pdb:5PJ7|rcsb pdb:5PJ8|rcsb pdb:5PJ9|rcsb pdb:5PJA|rcsb pdb:5PJB|rcsb pdb:5PJC|rcsb pdb:5PJD|rcsb pdb:5PJE|rcsb pdb:5PJF|rcsb pdb:5PJG|rcsb pdb:5PJ5|rcsb pdb:5PJH|rcsb pdb:5PJI|rcsb pdb:5PJJ|rcsb pdb:5PJK|rcsb pdb:5PJL|rcsb pdb:5PJM|rcsb pdb:5PJN|rcsb pdb:5PJO|rcsb pdb:5PJP|rcsb pdb:5PJQ|rcsb pdb:5PJR|rcsb pdb:5PJS|rcsb pdb:6ETT|rcsb pdb:6ETU|rcsb pdb:5PJT|rcsb pdb:6ETV|rcsb pdb:6ETW|rcsb pdb:6F5Q|rcsb pdb:6F5R|rcsb pdb:6F5S|rcsb pdb:6F5T|rcsb pdb:6H0W|rcsb pdb:6H0X|rcsb pdb:6H0Y|rcsb pdb:6H0Z|rcsb pdb:6H10|rcsb pdb:6H11|reactome:R-HSA-3214842|ensembl:ENSG00000186280(gene)|ensembl:ENST00000335080(transcript)|ensembl:ENST00000536741(transcript)|ensembl:ENST00000610872(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|rcsb pdb:5PJV|rcsb pdb:5PJW|rcsb pdb:5PJX|rcsb pdb:5PJY|rcsb pdb:5PJZ|rcsb pdb:5PK0|rcsb pdb:5PK1|rcsb pdb:5PK2|rcsb pdb:5PJU|rcsb pdb:5PK3|rcsb pdb:5PK4|rcsb pdb:5PK5|rcsb pdb:5PK6|rcsb pdb:5PK7|rcsb pdb:5PK8|rcsb pdb:5PK9|rcsb pdb:5PKA|rcsb pdb:5PKB|rcsb pdb:5PKC|rcsb pdb:5PKD|rcsb pdb:5PKE|rcsb pdb:5PKF|rcsb pdb:5PKG|rcsb pdb:5PKH|rcsb pdb:5PKI|rcsb pdb:5PKJ|rcsb pdb:5PKK|rcsb pdb:5PKL|rcsb pdb:5PKM|rcsb pdb:5PKN|rcsb pdb:5PKO|rcsb pdb:5PKP|rcsb pdb:5PKQ|rcsb pdb:5PKR|rcsb pdb:5PKS|rcsb pdb:5PKT|rcsb pdb:5PKU|rcsb pdb:5PKV|rcsb pdb:5PKW|rcsb pdb:5PKX|rcsb pdb:5PKY|rcsb pdb:5PKZ|rcsb pdb:5PL0|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072562"(blood microparticle)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|mint:Q6B0I6|rcsb pdb:3DXT|rcsb pdb:3DXU|rcsb pdb:4D6Q|rcsb pdb:4D6R|rcsb pdb:4D6S|rcsb pdb:4HON|rcsb pdb:5PL2|rcsb pdb:5PL3|rcsb pdb:5PL1|rcsb pdb:5PL4|rcsb pdb:5PL5|rcsb pdb:5PL6|rcsb pdb:5PL7|rcsb pdb:5PL8|rcsb pdb:5PL9|rcsb pdb:5PLA|rcsb pdb:5PLB|rcsb pdb:5PLC|rcsb pdb:5PLD|rcsb pdb:5PLE|rcsb pdb:5PLF|rcsb pdb:5PLG|rcsb pdb:5PLH|rcsb pdb:5PLI|rcsb pdb:5PLJ|rcsb pdb:5PLK|rcsb pdb:5PLL|rcsb pdb:5PLM|rcsb pdb:5PLN|rcsb pdb:5PLO|rcsb pdb:5PLP|rcsb pdb:5PLQ|rcsb pdb:5PLR|rcsb pdb:5PLS|rcsb pdb:5F5A|rcsb pdb:5F5C|rcsb pdb:5FP4|rcsb pdb:5FP7|rcsb pdb:5FP8|rcsb pdb:5FP9|rcsb pdb:5FPA|rcsb pdb:5FPB|rcsb pdb:5PH0|rcsb pdb:5PH1|rcsb pdb:5PH2|rcsb pdb:5PH3|rcsb pdb:5PH4|rcsb pdb:4HOO|rcsb pdb:5PH5|rcsb pdb:5PH6|rcsb pdb:5PH7|rcsb pdb:5PH8|rcsb pdb:5PH9|rcsb pdb:5PHA|rcsb pdb:5PHB|rcsb pdb:5PHC|rcsb pdb:5PHD|rcsb pdb:5PHE|rcsb pdb:5PLU|rcsb pdb:5PLV|rcsb pdb:5PLW|rcsb pdb:5PLX|rcsb pdb:5PLY|rcsb pdb:5PLZ|rcsb pdb:5PM0|rcsb pdb:5PM1|rcsb pdb:5PM2|rcsb pdb:5PM3|rcsb pdb:5PM4|rcsb pdb:5PM5|rcsb pdb:5PM6|rcsb pdb:5PM7|rcsb pdb:5PM8|rcsb pdb:5PM9|rcsb pdb:5PMA|rcsb pdb:5PMB|rcsb pdb:5PMC|rcsb pdb:5PMD|rcsb pdb:5PME|rcsb pdb:5PMF|rcsb pdb:5PMG|rcsb pdb:5PMH|rcsb pdb:5PMI|rcsb pdb:5PMJ|rcsb pdb:5PMK|rcsb pdb:5PML|rcsb pdb:5PMM|rcsb pdb:5PMN|rcsb pdb:5PMO|rcsb pdb:5PMP|rcsb pdb:5PMQ|rcsb pdb:5PMR|rcsb pdb:5PMS|rcsb pdb:5PMT|rcsb pdb:5PMU|rcsb pdb:5PMV|rcsb pdb:5PMW|rcsb pdb:5PMX|rcsb pdb:5PMY|rcsb pdb:5PMZ|rcsb pdb:5PN0|rcsb pdb:5PN1|rcsb pdb:5PN2|rcsb pdb:5PN3|rcsb pdb:5PN4|rcsb pdb:5PN5|rcsb pdb:5PN6|rcsb pdb:5PN7|rcsb pdb:5PN8|rcsb pdb:5PN9|rcsb pdb:5PNA|rcsb pdb:5PNB|rcsb pdb:5PNC|rcsb pdb:5PND|rcsb pdb:5PNE|rcsb pdb:5PNF|rcsb pdb:5PNG|rcsb pdb:5PNH|rcsb pdb:5PNI|rcsb pdb:5PNJ|rcsb pdb:5PNK|rcsb pdb:5PNL|rcsb pdb:5PNM|rcsb pdb:5PLT|rcsb pdb:5PNN|rcsb pdb:5PNO|rcsb pdb:5PNP|rcsb pdb:5PNQ|rcsb pdb:5PNR|rcsb pdb:5PNS|rcsb pdb:5PNU|rcsb pdb:5PNV|rcsb pdb:5PNW|rcsb pdb:6ETE|rcsb pdb:6ETG|rcsb pdb:6ETS|rcsb pdb:5PHJ|rcsb pdb:5PHK|rcsb pdb:5PHL|rcsb pdb:5PHM|rcsb pdb:5PHN|rcsb pdb:5PHO|rcsb pdb:5PHP|rcsb pdb:5PHQ|rcsb pdb:5PHR|rcsb pdb:5PHS|rcsb pdb:5PHT|rcsb pdb:5PHU|rcsb pdb:5PHV|rcsb pdb:5PHF|rcsb pdb:5PHG|rcsb pdb:5PHH|rcsb pdb:5PHI|rcsb pdb:5PHW|rcsb pdb:5PHX|rcsb pdb:5PHY|rcsb pdb:5PHZ|rcsb pdb:5PI0|rcsb pdb:5PI1|rcsb pdb:5PI2|rcsb pdb:5PI3|rcsb pdb:5PI4|dip:DIP-29606N refseq:NP_000994.1|refseq:NP_998890.1|ensembl:ENSG00000137818(gene)|ensembl:ENST00000260379(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0043021"(ribonucleoprotein complex binding)|interpro:IPR027534|interpro:IPR038716|mint:P05386|rcsb pdb:2LBF|rcsb pdb:4BEH|rcsb pdb:4V6X|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:svQfKWBCSAPSGFAV5YPZXFvcqkk9606 rogid:rHSXz4ZCJy+JH6OrjUgHiTK85mo9606 rigid:7fqj2Gju3X4HbV0gQNAzWx9cUhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6B0I6 uniprotkb:P48735 intact:EBI-4311651|uniprotkb:Q9NW76|uniprotkb:B3KPC4|uniprotkb:Q9NT41|uniprotkb:Q0VF39|ensembl:ENSP00000334181|ensembl:ENSP00000460897|ensembl:ENSP00000482224 intact:EBI-3931130|uniprotkb:Q96GT3|uniprotkb:B2R6L6|ensembl:ENSP00000331897|uniprotkb:B4DFL2 psi-mi:kdm4d_human(display_long)|uniprotkb:KDM4D(gene name)|psi-mi:KDM4D(display_short)|uniprotkb:JHDM3D(gene name synonym)|uniprotkb:JMJD2D(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3D(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2D(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4D"(gene name synonym) psi-mi:idhp_human(display_long)|uniprotkb:IDH2(gene name)|psi-mi:IDH2(display_short)|uniprotkb:ICD-M(gene name synonym)|uniprotkb:IDP(gene name synonym)|uniprotkb:"NADP(+)-specific ICDH"(gene name synonym)|uniprotkb:Oxalosuccinate decarboxylase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480104|imex:IM-26985-481 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060509.2|rcsb pdb:5PI6|rcsb pdb:5PI7|rcsb pdb:5PI8|rcsb pdb:5PI9|rcsb pdb:5PIA|rcsb pdb:5PIB|rcsb pdb:5PIC|rcsb pdb:5PID|rcsb pdb:5PIE|rcsb pdb:5PIF|rcsb pdb:5PIG|rcsb pdb:5PIH|rcsb pdb:5PII|rcsb pdb:5PIJ|rcsb pdb:5PIK|rcsb pdb:5PIL|rcsb pdb:5PIM|rcsb pdb:5PIN|rcsb pdb:5PIO|rcsb pdb:5PIP|rcsb pdb:5PIQ|rcsb pdb:5PIR|rcsb pdb:5PIS|rcsb pdb:5PIT|rcsb pdb:5PIU|rcsb pdb:5PIV|rcsb pdb:5PIW|rcsb pdb:5PIX|rcsb pdb:5PIY|rcsb pdb:5PIZ|rcsb pdb:5PJ0|rcsb pdb:5PI5|rcsb pdb:5PJ1|rcsb pdb:5PJ2|rcsb pdb:5PJ3|rcsb pdb:5PJ4|rcsb pdb:5PJ6|rcsb pdb:5PJ7|rcsb pdb:5PJ8|rcsb pdb:5PJ9|rcsb pdb:5PJA|rcsb pdb:5PJB|rcsb pdb:5PJC|rcsb pdb:5PJD|rcsb pdb:5PJE|rcsb pdb:5PJF|rcsb pdb:5PJG|rcsb pdb:5PJ5|rcsb pdb:5PJH|rcsb pdb:5PJI|rcsb pdb:5PJJ|rcsb pdb:5PJK|rcsb pdb:5PJL|rcsb pdb:5PJM|rcsb pdb:5PJN|rcsb pdb:5PJO|rcsb pdb:5PJP|rcsb pdb:5PJQ|rcsb pdb:5PJR|rcsb pdb:5PJS|rcsb pdb:6ETT|rcsb pdb:6ETU|rcsb pdb:5PJT|rcsb pdb:6ETV|rcsb pdb:6ETW|rcsb pdb:6F5Q|rcsb pdb:6F5R|rcsb pdb:6F5S|rcsb pdb:6F5T|rcsb pdb:6H0W|rcsb pdb:6H0X|rcsb pdb:6H0Y|rcsb pdb:6H0Z|rcsb pdb:6H10|rcsb pdb:6H11|reactome:R-HSA-3214842|ensembl:ENSG00000186280(gene)|ensembl:ENST00000335080(transcript)|ensembl:ENST00000536741(transcript)|ensembl:ENST00000610872(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|rcsb pdb:5PJV|rcsb pdb:5PJW|rcsb pdb:5PJX|rcsb pdb:5PJY|rcsb pdb:5PJZ|rcsb pdb:5PK0|rcsb pdb:5PK1|rcsb pdb:5PK2|rcsb pdb:5PJU|rcsb pdb:5PK3|rcsb pdb:5PK4|rcsb pdb:5PK5|rcsb pdb:5PK6|rcsb pdb:5PK7|rcsb pdb:5PK8|rcsb pdb:5PK9|rcsb pdb:5PKA|rcsb pdb:5PKB|rcsb pdb:5PKC|rcsb pdb:5PKD|rcsb pdb:5PKE|rcsb pdb:5PKF|rcsb pdb:5PKG|rcsb pdb:5PKH|rcsb pdb:5PKI|rcsb pdb:5PKJ|rcsb pdb:5PKK|rcsb pdb:5PKL|rcsb pdb:5PKM|rcsb pdb:5PKN|rcsb pdb:5PKO|rcsb pdb:5PKP|rcsb pdb:5PKQ|rcsb pdb:5PKR|rcsb pdb:5PKS|rcsb pdb:5PKT|rcsb pdb:5PKU|rcsb pdb:5PKV|rcsb pdb:5PKW|rcsb pdb:5PKX|rcsb pdb:5PKY|rcsb pdb:5PKZ|rcsb pdb:5PL0|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072562"(blood microparticle)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|mint:Q6B0I6|rcsb pdb:3DXT|rcsb pdb:3DXU|rcsb pdb:4D6Q|rcsb pdb:4D6R|rcsb pdb:4D6S|rcsb pdb:4HON|rcsb pdb:5PL2|rcsb pdb:5PL3|rcsb pdb:5PL1|rcsb pdb:5PL4|rcsb pdb:5PL5|rcsb pdb:5PL6|rcsb pdb:5PL7|rcsb pdb:5PL8|rcsb pdb:5PL9|rcsb pdb:5PLA|rcsb pdb:5PLB|rcsb pdb:5PLC|rcsb pdb:5PLD|rcsb pdb:5PLE|rcsb pdb:5PLF|rcsb pdb:5PLG|rcsb pdb:5PLH|rcsb pdb:5PLI|rcsb pdb:5PLJ|rcsb pdb:5PLK|rcsb pdb:5PLL|rcsb pdb:5PLM|rcsb pdb:5PLN|rcsb pdb:5PLO|rcsb pdb:5PLP|rcsb pdb:5PLQ|rcsb pdb:5PLR|rcsb pdb:5PLS|rcsb pdb:5F5A|rcsb pdb:5F5C|rcsb pdb:5FP4|rcsb pdb:5FP7|rcsb pdb:5FP8|rcsb pdb:5FP9|rcsb pdb:5FPA|rcsb pdb:5FPB|rcsb pdb:5PH0|rcsb pdb:5PH1|rcsb pdb:5PH2|rcsb pdb:5PH3|rcsb pdb:5PH4|rcsb pdb:4HOO|rcsb pdb:5PH5|rcsb pdb:5PH6|rcsb pdb:5PH7|rcsb pdb:5PH8|rcsb pdb:5PH9|rcsb pdb:5PHA|rcsb pdb:5PHB|rcsb pdb:5PHC|rcsb pdb:5PHD|rcsb pdb:5PHE|rcsb pdb:5PLU|rcsb pdb:5PLV|rcsb pdb:5PLW|rcsb pdb:5PLX|rcsb pdb:5PLY|rcsb pdb:5PLZ|rcsb pdb:5PM0|rcsb pdb:5PM1|rcsb pdb:5PM2|rcsb pdb:5PM3|rcsb pdb:5PM4|rcsb pdb:5PM5|rcsb pdb:5PM6|rcsb pdb:5PM7|rcsb pdb:5PM8|rcsb pdb:5PM9|rcsb pdb:5PMA|rcsb pdb:5PMB|rcsb pdb:5PMC|rcsb pdb:5PMD|rcsb pdb:5PME|rcsb pdb:5PMF|rcsb pdb:5PMG|rcsb pdb:5PMH|rcsb pdb:5PMI|rcsb pdb:5PMJ|rcsb pdb:5PMK|rcsb pdb:5PML|rcsb pdb:5PMM|rcsb pdb:5PMN|rcsb pdb:5PMO|rcsb pdb:5PMP|rcsb pdb:5PMQ|rcsb pdb:5PMR|rcsb pdb:5PMS|rcsb pdb:5PMT|rcsb pdb:5PMU|rcsb pdb:5PMV|rcsb pdb:5PMW|rcsb pdb:5PMX|rcsb pdb:5PMY|rcsb pdb:5PMZ|rcsb pdb:5PN0|rcsb pdb:5PN1|rcsb pdb:5PN2|rcsb pdb:5PN3|rcsb pdb:5PN4|rcsb pdb:5PN5|rcsb pdb:5PN6|rcsb pdb:5PN7|rcsb pdb:5PN8|rcsb pdb:5PN9|rcsb pdb:5PNA|rcsb pdb:5PNB|rcsb pdb:5PNC|rcsb pdb:5PND|rcsb pdb:5PNE|rcsb pdb:5PNF|rcsb pdb:5PNG|rcsb pdb:5PNH|rcsb pdb:5PNI|rcsb pdb:5PNJ|rcsb pdb:5PNK|rcsb pdb:5PNL|rcsb pdb:5PNM|rcsb pdb:5PLT|rcsb pdb:5PNN|rcsb pdb:5PNO|rcsb pdb:5PNP|rcsb pdb:5PNQ|rcsb pdb:5PNR|rcsb pdb:5PNS|rcsb pdb:5PNU|rcsb pdb:5PNV|rcsb pdb:5PNW|rcsb pdb:6ETE|rcsb pdb:6ETG|rcsb pdb:6ETS|rcsb pdb:5PHJ|rcsb pdb:5PHK|rcsb pdb:5PHL|rcsb pdb:5PHM|rcsb pdb:5PHN|rcsb pdb:5PHO|rcsb pdb:5PHP|rcsb pdb:5PHQ|rcsb pdb:5PHR|rcsb pdb:5PHS|rcsb pdb:5PHT|rcsb pdb:5PHU|rcsb pdb:5PHV|rcsb pdb:5PHF|rcsb pdb:5PHG|rcsb pdb:5PHH|rcsb pdb:5PHI|rcsb pdb:5PHW|rcsb pdb:5PHX|rcsb pdb:5PHY|rcsb pdb:5PHZ|rcsb pdb:5PI0|rcsb pdb:5PI1|rcsb pdb:5PI2|rcsb pdb:5PI3|rcsb pdb:5PI4|dip:DIP-29606N ensembl:ENSG00000182054(gene)|ensembl:ENST00000330062(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004450"("isocitrate dehydrogenase (NADP+) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006097"(glyoxylate cycle)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006739"(NADP metabolic process)|go:"GO:0006741"(NADP biosynthetic process)|go:"GO:0051287"(NAD binding)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903976"(negative regulation of glial cell migration)|go:"GO:1904465"(negative regulation of matrix metallopeptidase secretion)|interpro:IPR004790(Isocitrate dehydrogenase NADP-dependent, eukaryotic)|interpro:IPR019818|interpro:IPR024084|mint:P48735|rcsb pdb:4JA8|rcsb pdb:5GIS|rcsb pdb:5I95|rcsb pdb:5I96|rcsb pdb:5SVN|rcsb pdb:5SVO|rcsb pdb:6ADI|rcsb pdb:6UJ7|rcsb pdb:6UJ8|rcsb pdb:6UJ9|rcsb pdb:6VFZ|reactome:R-HSA-2151201|reactome:R-HSA-71403|refseq:NP_002159.2|refseq:NP_001276839.1|refseq:NP_001277043.1|dip:DIP-61416N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:svQfKWBCSAPSGFAV5YPZXFvcqkk9606 rogid:CeuTM4HmOk3+OKkWlOt9JfNlCIM9606 rigid:7fqj2Gju3X4HbV0gQNAzWx9cUhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6B0I6 uniprotkb:P62633 intact:EBI-4311651|uniprotkb:Q9NW76|uniprotkb:B3KPC4|uniprotkb:Q9NT41|uniprotkb:Q0VF39|ensembl:ENSP00000334181|ensembl:ENSP00000460897|ensembl:ENSP00000482224 intact:EBI-1047529|uniprotkb:D3DNB9|uniprotkb:D3DNC0|uniprotkb:D3DNC1|uniprotkb:P20694|uniprotkb:Q5QJR0|uniprotkb:Q6PJI7|uniprotkb:Q96NV3|uniprotkb:B4DP17|uniprotkb:Q4JGY1|uniprotkb:B2RAV9|uniprotkb:Q4JGY0|uniprotkb:Q5U0E9|ensembl:ENSP00000410619|uniprotkb:A8K7V4|uniprotkb:E9PDR7 psi-mi:kdm4d_human(display_long)|uniprotkb:KDM4D(gene name)|psi-mi:KDM4D(display_short)|uniprotkb:JHDM3D(gene name synonym)|uniprotkb:JMJD2D(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3D(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2D(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4D"(gene name synonym) psi-mi:cnbp_human(display_long)|uniprotkb:Zinc finger protein 9(gene name synonym)|uniprotkb:CNBP(gene name)|psi-mi:CNBP(display_short)|uniprotkb:ZNF9(gene name synonym)|uniprotkb:RNF163(gene name synonym)|uniprotkb:Cellular nucleic acid-binding protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480104|imex:IM-26985-481 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060509.2|rcsb pdb:5PI6|rcsb pdb:5PI7|rcsb pdb:5PI8|rcsb pdb:5PI9|rcsb pdb:5PIA|rcsb pdb:5PIB|rcsb pdb:5PIC|rcsb pdb:5PID|rcsb pdb:5PIE|rcsb pdb:5PIF|rcsb pdb:5PIG|rcsb pdb:5PIH|rcsb pdb:5PII|rcsb pdb:5PIJ|rcsb pdb:5PIK|rcsb pdb:5PIL|rcsb pdb:5PIM|rcsb pdb:5PIN|rcsb pdb:5PIO|rcsb pdb:5PIP|rcsb pdb:5PIQ|rcsb pdb:5PIR|rcsb pdb:5PIS|rcsb pdb:5PIT|rcsb pdb:5PIU|rcsb pdb:5PIV|rcsb pdb:5PIW|rcsb pdb:5PIX|rcsb pdb:5PIY|rcsb pdb:5PIZ|rcsb pdb:5PJ0|rcsb pdb:5PI5|rcsb pdb:5PJ1|rcsb pdb:5PJ2|rcsb pdb:5PJ3|rcsb pdb:5PJ4|rcsb pdb:5PJ6|rcsb pdb:5PJ7|rcsb pdb:5PJ8|rcsb pdb:5PJ9|rcsb pdb:5PJA|rcsb pdb:5PJB|rcsb pdb:5PJC|rcsb pdb:5PJD|rcsb pdb:5PJE|rcsb pdb:5PJF|rcsb pdb:5PJG|rcsb pdb:5PJ5|rcsb pdb:5PJH|rcsb pdb:5PJI|rcsb pdb:5PJJ|rcsb pdb:5PJK|rcsb pdb:5PJL|rcsb pdb:5PJM|rcsb pdb:5PJN|rcsb pdb:5PJO|rcsb pdb:5PJP|rcsb pdb:5PJQ|rcsb pdb:5PJR|rcsb pdb:5PJS|rcsb pdb:6ETT|rcsb pdb:6ETU|rcsb pdb:5PJT|rcsb pdb:6ETV|rcsb pdb:6ETW|rcsb pdb:6F5Q|rcsb pdb:6F5R|rcsb pdb:6F5S|rcsb pdb:6F5T|rcsb pdb:6H0W|rcsb pdb:6H0X|rcsb pdb:6H0Y|rcsb pdb:6H0Z|rcsb pdb:6H10|rcsb pdb:6H11|reactome:R-HSA-3214842|ensembl:ENSG00000186280(gene)|ensembl:ENST00000335080(transcript)|ensembl:ENST00000536741(transcript)|ensembl:ENST00000610872(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|rcsb pdb:5PJV|rcsb pdb:5PJW|rcsb pdb:5PJX|rcsb pdb:5PJY|rcsb pdb:5PJZ|rcsb pdb:5PK0|rcsb pdb:5PK1|rcsb pdb:5PK2|rcsb pdb:5PJU|rcsb pdb:5PK3|rcsb pdb:5PK4|rcsb pdb:5PK5|rcsb pdb:5PK6|rcsb pdb:5PK7|rcsb pdb:5PK8|rcsb pdb:5PK9|rcsb pdb:5PKA|rcsb pdb:5PKB|rcsb pdb:5PKC|rcsb pdb:5PKD|rcsb pdb:5PKE|rcsb pdb:5PKF|rcsb pdb:5PKG|rcsb pdb:5PKH|rcsb pdb:5PKI|rcsb pdb:5PKJ|rcsb pdb:5PKK|rcsb pdb:5PKL|rcsb pdb:5PKM|rcsb pdb:5PKN|rcsb pdb:5PKO|rcsb pdb:5PKP|rcsb pdb:5PKQ|rcsb pdb:5PKR|rcsb pdb:5PKS|rcsb pdb:5PKT|rcsb pdb:5PKU|rcsb pdb:5PKV|rcsb pdb:5PKW|rcsb pdb:5PKX|rcsb pdb:5PKY|rcsb pdb:5PKZ|rcsb pdb:5PL0|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072562"(blood microparticle)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|mint:Q6B0I6|rcsb pdb:3DXT|rcsb pdb:3DXU|rcsb pdb:4D6Q|rcsb pdb:4D6R|rcsb pdb:4D6S|rcsb pdb:4HON|rcsb pdb:5PL2|rcsb pdb:5PL3|rcsb pdb:5PL1|rcsb pdb:5PL4|rcsb pdb:5PL5|rcsb pdb:5PL6|rcsb pdb:5PL7|rcsb pdb:5PL8|rcsb pdb:5PL9|rcsb pdb:5PLA|rcsb pdb:5PLB|rcsb pdb:5PLC|rcsb pdb:5PLD|rcsb pdb:5PLE|rcsb pdb:5PLF|rcsb pdb:5PLG|rcsb pdb:5PLH|rcsb pdb:5PLI|rcsb pdb:5PLJ|rcsb pdb:5PLK|rcsb pdb:5PLL|rcsb pdb:5PLM|rcsb pdb:5PLN|rcsb pdb:5PLO|rcsb pdb:5PLP|rcsb pdb:5PLQ|rcsb pdb:5PLR|rcsb pdb:5PLS|rcsb pdb:5F5A|rcsb pdb:5F5C|rcsb pdb:5FP4|rcsb pdb:5FP7|rcsb pdb:5FP8|rcsb pdb:5FP9|rcsb pdb:5FPA|rcsb pdb:5FPB|rcsb pdb:5PH0|rcsb pdb:5PH1|rcsb pdb:5PH2|rcsb pdb:5PH3|rcsb pdb:5PH4|rcsb pdb:4HOO|rcsb pdb:5PH5|rcsb pdb:5PH6|rcsb pdb:5PH7|rcsb pdb:5PH8|rcsb pdb:5PH9|rcsb pdb:5PHA|rcsb pdb:5PHB|rcsb pdb:5PHC|rcsb pdb:5PHD|rcsb pdb:5PHE|rcsb pdb:5PLU|rcsb pdb:5PLV|rcsb pdb:5PLW|rcsb pdb:5PLX|rcsb pdb:5PLY|rcsb pdb:5PLZ|rcsb pdb:5PM0|rcsb pdb:5PM1|rcsb pdb:5PM2|rcsb pdb:5PM3|rcsb pdb:5PM4|rcsb pdb:5PM5|rcsb pdb:5PM6|rcsb pdb:5PM7|rcsb pdb:5PM8|rcsb pdb:5PM9|rcsb pdb:5PMA|rcsb pdb:5PMB|rcsb pdb:5PMC|rcsb pdb:5PMD|rcsb pdb:5PME|rcsb pdb:5PMF|rcsb pdb:5PMG|rcsb pdb:5PMH|rcsb pdb:5PMI|rcsb pdb:5PMJ|rcsb pdb:5PMK|rcsb pdb:5PML|rcsb pdb:5PMM|rcsb pdb:5PMN|rcsb pdb:5PMO|rcsb pdb:5PMP|rcsb pdb:5PMQ|rcsb pdb:5PMR|rcsb pdb:5PMS|rcsb pdb:5PMT|rcsb pdb:5PMU|rcsb pdb:5PMV|rcsb pdb:5PMW|rcsb pdb:5PMX|rcsb pdb:5PMY|rcsb pdb:5PMZ|rcsb pdb:5PN0|rcsb pdb:5PN1|rcsb pdb:5PN2|rcsb pdb:5PN3|rcsb pdb:5PN4|rcsb pdb:5PN5|rcsb pdb:5PN6|rcsb pdb:5PN7|rcsb pdb:5PN8|rcsb pdb:5PN9|rcsb pdb:5PNA|rcsb pdb:5PNB|rcsb pdb:5PNC|rcsb pdb:5PND|rcsb pdb:5PNE|rcsb pdb:5PNF|rcsb pdb:5PNG|rcsb pdb:5PNH|rcsb pdb:5PNI|rcsb pdb:5PNJ|rcsb pdb:5PNK|rcsb pdb:5PNL|rcsb pdb:5PNM|rcsb pdb:5PLT|rcsb pdb:5PNN|rcsb pdb:5PNO|rcsb pdb:5PNP|rcsb pdb:5PNQ|rcsb pdb:5PNR|rcsb pdb:5PNS|rcsb pdb:5PNU|rcsb pdb:5PNV|rcsb pdb:5PNW|rcsb pdb:6ETE|rcsb pdb:6ETG|rcsb pdb:6ETS|rcsb pdb:5PHJ|rcsb pdb:5PHK|rcsb pdb:5PHL|rcsb pdb:5PHM|rcsb pdb:5PHN|rcsb pdb:5PHO|rcsb pdb:5PHP|rcsb pdb:5PHQ|rcsb pdb:5PHR|rcsb pdb:5PHS|rcsb pdb:5PHT|rcsb pdb:5PHU|rcsb pdb:5PHV|rcsb pdb:5PHF|rcsb pdb:5PHG|rcsb pdb:5PHH|rcsb pdb:5PHI|rcsb pdb:5PHW|rcsb pdb:5PHX|rcsb pdb:5PHY|rcsb pdb:5PHZ|rcsb pdb:5PI0|rcsb pdb:5PI1|rcsb pdb:5PI2|rcsb pdb:5PI3|rcsb pdb:5PI4|dip:DIP-29606N refseq:NP_001120664.1|refseq:NP_001120668.1|refseq:NP_003409.1|refseq:NP_001120665.1|refseq:NP_001120666.1|ensembl:ENSG00000169714(gene)|ensembl:ENST00000422453(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0071919"(G-quadruplex DNA formation)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR036875|mint:P62633|refseq:NP_001120667.1 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:svQfKWBCSAPSGFAV5YPZXFvcqkk9606 rogid:x5yqfxy/s3fE/6EmvjrEe7PmanQ9606 rigid:7fqj2Gju3X4HbV0gQNAzWx9cUhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6B0I6 uniprotkb:Q8IX12 intact:EBI-4311651|uniprotkb:Q9NW76|uniprotkb:B3KPC4|uniprotkb:Q9NT41|uniprotkb:Q0VF39|ensembl:ENSP00000334181|ensembl:ENSP00000460897|ensembl:ENSP00000482224 intact:EBI-356265|ensembl:ENSP00000265872|uniprotkb:A0JLT7|uniprotkb:A1L4P7|uniprotkb:A8K9D4|uniprotkb:B4DNP8|uniprotkb:B4DRK8|uniprotkb:Q5EBM3|uniprotkb:Q32NE3|uniprotkb:Q5VUP6|uniprotkb:Q6PIZ0|uniprotkb:Q6X935|uniprotkb:Q9H8N4|uniprotkb:Q9NVA7|uniprotkb:Q9NVQ0|uniprotkb:Q9NWM6 psi-mi:kdm4d_human(display_long)|uniprotkb:KDM4D(gene name)|psi-mi:KDM4D(display_short)|uniprotkb:JHDM3D(gene name synonym)|uniprotkb:JMJD2D(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3D(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2D(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4D"(gene name synonym) psi-mi:ccar1_human(display_long)|uniprotkb:CCAR1(gene name)|psi-mi:CCAR1(display_short)|uniprotkb:CARP1(gene name synonym)|uniprotkb:DIS(gene name synonym)|uniprotkb:Cell cycle and apoptosis regulatory protein 1(gene name synonym)|uniprotkb:Death inducer with SAP domain(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480104|imex:IM-26985-481 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060509.2|rcsb pdb:5PI6|rcsb pdb:5PI7|rcsb pdb:5PI8|rcsb pdb:5PI9|rcsb pdb:5PIA|rcsb pdb:5PIB|rcsb pdb:5PIC|rcsb pdb:5PID|rcsb pdb:5PIE|rcsb pdb:5PIF|rcsb pdb:5PIG|rcsb pdb:5PIH|rcsb pdb:5PII|rcsb pdb:5PIJ|rcsb pdb:5PIK|rcsb pdb:5PIL|rcsb pdb:5PIM|rcsb pdb:5PIN|rcsb pdb:5PIO|rcsb pdb:5PIP|rcsb pdb:5PIQ|rcsb pdb:5PIR|rcsb pdb:5PIS|rcsb pdb:5PIT|rcsb pdb:5PIU|rcsb pdb:5PIV|rcsb pdb:5PIW|rcsb pdb:5PIX|rcsb pdb:5PIY|rcsb pdb:5PIZ|rcsb pdb:5PJ0|rcsb pdb:5PI5|rcsb pdb:5PJ1|rcsb pdb:5PJ2|rcsb pdb:5PJ3|rcsb pdb:5PJ4|rcsb pdb:5PJ6|rcsb pdb:5PJ7|rcsb pdb:5PJ8|rcsb pdb:5PJ9|rcsb pdb:5PJA|rcsb pdb:5PJB|rcsb pdb:5PJC|rcsb pdb:5PJD|rcsb pdb:5PJE|rcsb pdb:5PJF|rcsb pdb:5PJG|rcsb pdb:5PJ5|rcsb pdb:5PJH|rcsb pdb:5PJI|rcsb pdb:5PJJ|rcsb pdb:5PJK|rcsb pdb:5PJL|rcsb pdb:5PJM|rcsb pdb:5PJN|rcsb pdb:5PJO|rcsb pdb:5PJP|rcsb pdb:5PJQ|rcsb pdb:5PJR|rcsb pdb:5PJS|rcsb pdb:6ETT|rcsb pdb:6ETU|rcsb pdb:5PJT|rcsb pdb:6ETV|rcsb pdb:6ETW|rcsb pdb:6F5Q|rcsb pdb:6F5R|rcsb pdb:6F5S|rcsb pdb:6F5T|rcsb pdb:6H0W|rcsb pdb:6H0X|rcsb pdb:6H0Y|rcsb pdb:6H0Z|rcsb pdb:6H10|rcsb pdb:6H11|reactome:R-HSA-3214842|ensembl:ENSG00000186280(gene)|ensembl:ENST00000335080(transcript)|ensembl:ENST00000536741(transcript)|ensembl:ENST00000610872(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|rcsb pdb:5PJV|rcsb pdb:5PJW|rcsb pdb:5PJX|rcsb pdb:5PJY|rcsb pdb:5PJZ|rcsb pdb:5PK0|rcsb pdb:5PK1|rcsb pdb:5PK2|rcsb pdb:5PJU|rcsb pdb:5PK3|rcsb pdb:5PK4|rcsb pdb:5PK5|rcsb pdb:5PK6|rcsb pdb:5PK7|rcsb pdb:5PK8|rcsb pdb:5PK9|rcsb pdb:5PKA|rcsb pdb:5PKB|rcsb pdb:5PKC|rcsb pdb:5PKD|rcsb pdb:5PKE|rcsb pdb:5PKF|rcsb pdb:5PKG|rcsb pdb:5PKH|rcsb pdb:5PKI|rcsb pdb:5PKJ|rcsb pdb:5PKK|rcsb pdb:5PKL|rcsb pdb:5PKM|rcsb pdb:5PKN|rcsb pdb:5PKO|rcsb pdb:5PKP|rcsb pdb:5PKQ|rcsb pdb:5PKR|rcsb pdb:5PKS|rcsb pdb:5PKT|rcsb pdb:5PKU|rcsb pdb:5PKV|rcsb pdb:5PKW|rcsb pdb:5PKX|rcsb pdb:5PKY|rcsb pdb:5PKZ|rcsb pdb:5PL0|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072562"(blood microparticle)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|mint:Q6B0I6|rcsb pdb:3DXT|rcsb pdb:3DXU|rcsb pdb:4D6Q|rcsb pdb:4D6R|rcsb pdb:4D6S|rcsb pdb:4HON|rcsb pdb:5PL2|rcsb pdb:5PL3|rcsb pdb:5PL1|rcsb pdb:5PL4|rcsb pdb:5PL5|rcsb pdb:5PL6|rcsb pdb:5PL7|rcsb pdb:5PL8|rcsb pdb:5PL9|rcsb pdb:5PLA|rcsb pdb:5PLB|rcsb pdb:5PLC|rcsb pdb:5PLD|rcsb pdb:5PLE|rcsb pdb:5PLF|rcsb pdb:5PLG|rcsb pdb:5PLH|rcsb pdb:5PLI|rcsb pdb:5PLJ|rcsb pdb:5PLK|rcsb pdb:5PLL|rcsb pdb:5PLM|rcsb pdb:5PLN|rcsb pdb:5PLO|rcsb pdb:5PLP|rcsb pdb:5PLQ|rcsb pdb:5PLR|rcsb pdb:5PLS|rcsb pdb:5F5A|rcsb pdb:5F5C|rcsb pdb:5FP4|rcsb pdb:5FP7|rcsb pdb:5FP8|rcsb pdb:5FP9|rcsb pdb:5FPA|rcsb pdb:5FPB|rcsb pdb:5PH0|rcsb pdb:5PH1|rcsb pdb:5PH2|rcsb pdb:5PH3|rcsb pdb:5PH4|rcsb pdb:4HOO|rcsb pdb:5PH5|rcsb pdb:5PH6|rcsb pdb:5PH7|rcsb pdb:5PH8|rcsb pdb:5PH9|rcsb pdb:5PHA|rcsb pdb:5PHB|rcsb pdb:5PHC|rcsb pdb:5PHD|rcsb pdb:5PHE|rcsb pdb:5PLU|rcsb pdb:5PLV|rcsb pdb:5PLW|rcsb pdb:5PLX|rcsb pdb:5PLY|rcsb pdb:5PLZ|rcsb pdb:5PM0|rcsb pdb:5PM1|rcsb pdb:5PM2|rcsb pdb:5PM3|rcsb pdb:5PM4|rcsb pdb:5PM5|rcsb pdb:5PM6|rcsb pdb:5PM7|rcsb pdb:5PM8|rcsb pdb:5PM9|rcsb pdb:5PMA|rcsb pdb:5PMB|rcsb pdb:5PMC|rcsb pdb:5PMD|rcsb pdb:5PME|rcsb pdb:5PMF|rcsb pdb:5PMG|rcsb pdb:5PMH|rcsb pdb:5PMI|rcsb pdb:5PMJ|rcsb pdb:5PMK|rcsb pdb:5PML|rcsb pdb:5PMM|rcsb pdb:5PMN|rcsb pdb:5PMO|rcsb pdb:5PMP|rcsb pdb:5PMQ|rcsb pdb:5PMR|rcsb pdb:5PMS|rcsb pdb:5PMT|rcsb pdb:5PMU|rcsb pdb:5PMV|rcsb pdb:5PMW|rcsb pdb:5PMX|rcsb pdb:5PMY|rcsb pdb:5PMZ|rcsb pdb:5PN0|rcsb pdb:5PN1|rcsb pdb:5PN2|rcsb pdb:5PN3|rcsb pdb:5PN4|rcsb pdb:5PN5|rcsb pdb:5PN6|rcsb pdb:5PN7|rcsb pdb:5PN8|rcsb pdb:5PN9|rcsb pdb:5PNA|rcsb pdb:5PNB|rcsb pdb:5PNC|rcsb pdb:5PND|rcsb pdb:5PNE|rcsb pdb:5PNF|rcsb pdb:5PNG|rcsb pdb:5PNH|rcsb pdb:5PNI|rcsb pdb:5PNJ|rcsb pdb:5PNK|rcsb pdb:5PNL|rcsb pdb:5PNM|rcsb pdb:5PLT|rcsb pdb:5PNN|rcsb pdb:5PNO|rcsb pdb:5PNP|rcsb pdb:5PNQ|rcsb pdb:5PNR|rcsb pdb:5PNS|rcsb pdb:5PNU|rcsb pdb:5PNV|rcsb pdb:5PNW|rcsb pdb:6ETE|rcsb pdb:6ETG|rcsb pdb:6ETS|rcsb pdb:5PHJ|rcsb pdb:5PHK|rcsb pdb:5PHL|rcsb pdb:5PHM|rcsb pdb:5PHN|rcsb pdb:5PHO|rcsb pdb:5PHP|rcsb pdb:5PHQ|rcsb pdb:5PHR|rcsb pdb:5PHS|rcsb pdb:5PHT|rcsb pdb:5PHU|rcsb pdb:5PHV|rcsb pdb:5PHF|rcsb pdb:5PHG|rcsb pdb:5PHH|rcsb pdb:5PHI|rcsb pdb:5PHW|rcsb pdb:5PHX|rcsb pdb:5PHY|rcsb pdb:5PHZ|rcsb pdb:5PI0|rcsb pdb:5PI1|rcsb pdb:5PI2|rcsb pdb:5PI3|rcsb pdb:5PI4|dip:DIP-29606N ensembl:ENSG00000060339(gene)|ensembl:ENST00000265872(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR011992(EF-Hand type)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR025223|interpro:IPR025224|interpro:IPR025954|interpro:IPR036361|mint:Q8IX12|reactome:R-HSA-72163|refseq:NP_060707.2|refseq:NP_001269888.1|refseq:NP_001269889.1|dip:DIP-27607N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:svQfKWBCSAPSGFAV5YPZXFvcqkk9606 rogid:YnZve7StC4kAO8raUbp8T02jpe09606 rigid:7fqj2Gju3X4HbV0gQNAzWx9cUhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6B0I6 uniprotkb:Q05639 intact:EBI-4311651|uniprotkb:Q9NW76|uniprotkb:B3KPC4|uniprotkb:Q9NT41|uniprotkb:Q0VF39|ensembl:ENSP00000334181|ensembl:ENSP00000460897|ensembl:ENSP00000482224 intact:EBI-354943|ensembl:ENSP00000217182|uniprotkb:P54266|uniprotkb:Q0VGC7|uniprotkb:B5BUF3|uniprotkb:E1P5J1 psi-mi:kdm4d_human(display_long)|uniprotkb:KDM4D(gene name)|psi-mi:KDM4D(display_short)|uniprotkb:JHDM3D(gene name synonym)|uniprotkb:JMJD2D(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3D(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2D(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4D"(gene name synonym) psi-mi:ef1a2_human(display_long)|uniprotkb:EEF1A2(gene name)|psi-mi:EEF1A2(display_short)|uniprotkb:EEF1AL(gene name synonym)|uniprotkb:STN(gene name synonym)|uniprotkb:Eukaryotic elongation factor 1 A-2(gene name synonym)|uniprotkb:Statin-S1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480104|imex:IM-26985-481 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060509.2|rcsb pdb:5PI6|rcsb pdb:5PI7|rcsb pdb:5PI8|rcsb pdb:5PI9|rcsb pdb:5PIA|rcsb pdb:5PIB|rcsb pdb:5PIC|rcsb pdb:5PID|rcsb pdb:5PIE|rcsb pdb:5PIF|rcsb pdb:5PIG|rcsb pdb:5PIH|rcsb pdb:5PII|rcsb pdb:5PIJ|rcsb pdb:5PIK|rcsb pdb:5PIL|rcsb pdb:5PIM|rcsb pdb:5PIN|rcsb pdb:5PIO|rcsb pdb:5PIP|rcsb pdb:5PIQ|rcsb pdb:5PIR|rcsb pdb:5PIS|rcsb pdb:5PIT|rcsb pdb:5PIU|rcsb pdb:5PIV|rcsb pdb:5PIW|rcsb pdb:5PIX|rcsb pdb:5PIY|rcsb pdb:5PIZ|rcsb pdb:5PJ0|rcsb pdb:5PI5|rcsb pdb:5PJ1|rcsb pdb:5PJ2|rcsb pdb:5PJ3|rcsb pdb:5PJ4|rcsb pdb:5PJ6|rcsb pdb:5PJ7|rcsb pdb:5PJ8|rcsb pdb:5PJ9|rcsb pdb:5PJA|rcsb pdb:5PJB|rcsb pdb:5PJC|rcsb pdb:5PJD|rcsb pdb:5PJE|rcsb pdb:5PJF|rcsb pdb:5PJG|rcsb pdb:5PJ5|rcsb pdb:5PJH|rcsb pdb:5PJI|rcsb pdb:5PJJ|rcsb pdb:5PJK|rcsb pdb:5PJL|rcsb pdb:5PJM|rcsb pdb:5PJN|rcsb pdb:5PJO|rcsb pdb:5PJP|rcsb pdb:5PJQ|rcsb pdb:5PJR|rcsb pdb:5PJS|rcsb pdb:6ETT|rcsb pdb:6ETU|rcsb pdb:5PJT|rcsb pdb:6ETV|rcsb pdb:6ETW|rcsb pdb:6F5Q|rcsb pdb:6F5R|rcsb pdb:6F5S|rcsb pdb:6F5T|rcsb pdb:6H0W|rcsb pdb:6H0X|rcsb pdb:6H0Y|rcsb pdb:6H0Z|rcsb pdb:6H10|rcsb pdb:6H11|reactome:R-HSA-3214842|ensembl:ENSG00000186280(gene)|ensembl:ENST00000335080(transcript)|ensembl:ENST00000536741(transcript)|ensembl:ENST00000610872(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|rcsb pdb:5PJV|rcsb pdb:5PJW|rcsb pdb:5PJX|rcsb pdb:5PJY|rcsb pdb:5PJZ|rcsb pdb:5PK0|rcsb pdb:5PK1|rcsb pdb:5PK2|rcsb pdb:5PJU|rcsb pdb:5PK3|rcsb pdb:5PK4|rcsb pdb:5PK5|rcsb pdb:5PK6|rcsb pdb:5PK7|rcsb pdb:5PK8|rcsb pdb:5PK9|rcsb pdb:5PKA|rcsb pdb:5PKB|rcsb pdb:5PKC|rcsb pdb:5PKD|rcsb pdb:5PKE|rcsb pdb:5PKF|rcsb pdb:5PKG|rcsb pdb:5PKH|rcsb pdb:5PKI|rcsb pdb:5PKJ|rcsb pdb:5PKK|rcsb pdb:5PKL|rcsb pdb:5PKM|rcsb pdb:5PKN|rcsb pdb:5PKO|rcsb pdb:5PKP|rcsb pdb:5PKQ|rcsb pdb:5PKR|rcsb pdb:5PKS|rcsb pdb:5PKT|rcsb pdb:5PKU|rcsb pdb:5PKV|rcsb pdb:5PKW|rcsb pdb:5PKX|rcsb pdb:5PKY|rcsb pdb:5PKZ|rcsb pdb:5PL0|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072562"(blood microparticle)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|mint:Q6B0I6|rcsb pdb:3DXT|rcsb pdb:3DXU|rcsb pdb:4D6Q|rcsb pdb:4D6R|rcsb pdb:4D6S|rcsb pdb:4HON|rcsb pdb:5PL2|rcsb pdb:5PL3|rcsb pdb:5PL1|rcsb pdb:5PL4|rcsb pdb:5PL5|rcsb pdb:5PL6|rcsb pdb:5PL7|rcsb pdb:5PL8|rcsb pdb:5PL9|rcsb pdb:5PLA|rcsb pdb:5PLB|rcsb pdb:5PLC|rcsb pdb:5PLD|rcsb pdb:5PLE|rcsb pdb:5PLF|rcsb pdb:5PLG|rcsb pdb:5PLH|rcsb pdb:5PLI|rcsb pdb:5PLJ|rcsb pdb:5PLK|rcsb pdb:5PLL|rcsb pdb:5PLM|rcsb pdb:5PLN|rcsb pdb:5PLO|rcsb pdb:5PLP|rcsb pdb:5PLQ|rcsb pdb:5PLR|rcsb pdb:5PLS|rcsb pdb:5F5A|rcsb pdb:5F5C|rcsb pdb:5FP4|rcsb pdb:5FP7|rcsb pdb:5FP8|rcsb pdb:5FP9|rcsb pdb:5FPA|rcsb pdb:5FPB|rcsb pdb:5PH0|rcsb pdb:5PH1|rcsb pdb:5PH2|rcsb pdb:5PH3|rcsb pdb:5PH4|rcsb pdb:4HOO|rcsb pdb:5PH5|rcsb pdb:5PH6|rcsb pdb:5PH7|rcsb pdb:5PH8|rcsb pdb:5PH9|rcsb pdb:5PHA|rcsb pdb:5PHB|rcsb pdb:5PHC|rcsb pdb:5PHD|rcsb pdb:5PHE|rcsb pdb:5PLU|rcsb pdb:5PLV|rcsb pdb:5PLW|rcsb pdb:5PLX|rcsb pdb:5PLY|rcsb pdb:5PLZ|rcsb pdb:5PM0|rcsb pdb:5PM1|rcsb pdb:5PM2|rcsb pdb:5PM3|rcsb pdb:5PM4|rcsb pdb:5PM5|rcsb pdb:5PM6|rcsb pdb:5PM7|rcsb pdb:5PM8|rcsb pdb:5PM9|rcsb pdb:5PMA|rcsb pdb:5PMB|rcsb pdb:5PMC|rcsb pdb:5PMD|rcsb pdb:5PME|rcsb pdb:5PMF|rcsb pdb:5PMG|rcsb pdb:5PMH|rcsb pdb:5PMI|rcsb pdb:5PMJ|rcsb pdb:5PMK|rcsb pdb:5PML|rcsb pdb:5PMM|rcsb pdb:5PMN|rcsb pdb:5PMO|rcsb pdb:5PMP|rcsb pdb:5PMQ|rcsb pdb:5PMR|rcsb pdb:5PMS|rcsb pdb:5PMT|rcsb pdb:5PMU|rcsb pdb:5PMV|rcsb pdb:5PMW|rcsb pdb:5PMX|rcsb pdb:5PMY|rcsb pdb:5PMZ|rcsb pdb:5PN0|rcsb pdb:5PN1|rcsb pdb:5PN2|rcsb pdb:5PN3|rcsb pdb:5PN4|rcsb pdb:5PN5|rcsb pdb:5PN6|rcsb pdb:5PN7|rcsb pdb:5PN8|rcsb pdb:5PN9|rcsb pdb:5PNA|rcsb pdb:5PNB|rcsb pdb:5PNC|rcsb pdb:5PND|rcsb pdb:5PNE|rcsb pdb:5PNF|rcsb pdb:5PNG|rcsb pdb:5PNH|rcsb pdb:5PNI|rcsb pdb:5PNJ|rcsb pdb:5PNK|rcsb pdb:5PNL|rcsb pdb:5PNM|rcsb pdb:5PLT|rcsb pdb:5PNN|rcsb pdb:5PNO|rcsb pdb:5PNP|rcsb pdb:5PNQ|rcsb pdb:5PNR|rcsb pdb:5PNS|rcsb pdb:5PNU|rcsb pdb:5PNV|rcsb pdb:5PNW|rcsb pdb:6ETE|rcsb pdb:6ETG|rcsb pdb:6ETS|rcsb pdb:5PHJ|rcsb pdb:5PHK|rcsb pdb:5PHL|rcsb pdb:5PHM|rcsb pdb:5PHN|rcsb pdb:5PHO|rcsb pdb:5PHP|rcsb pdb:5PHQ|rcsb pdb:5PHR|rcsb pdb:5PHS|rcsb pdb:5PHT|rcsb pdb:5PHU|rcsb pdb:5PHV|rcsb pdb:5PHF|rcsb pdb:5PHG|rcsb pdb:5PHH|rcsb pdb:5PHI|rcsb pdb:5PHW|rcsb pdb:5PHX|rcsb pdb:5PHY|rcsb pdb:5PHZ|rcsb pdb:5PI0|rcsb pdb:5PI1|rcsb pdb:5PI2|rcsb pdb:5PI3|rcsb pdb:5PI4|dip:DIP-29606N ensembl:ENSG00000101210(gene)|ensembl:ENST00000217182(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0006412"(translation)|go:"GO:0006414"(translational elongation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0090218"(positive regulation of lipid kinase activity)|go:"GO:0098574"(cytoplasmic side of lysosomal membrane)|go:"GO:1904714"(regulation of chaperone-mediated autophagy)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR004539(Translation elongation factor EF1A, eukaryotic and archaeal)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|interpro:IPR031157|mint:Q05639|rcsb pdb:3C5J|reactome:R-HSA-156842|refseq:NP_001949.1|dip:DIP-40060N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:svQfKWBCSAPSGFAV5YPZXFvcqkk9606 rogid:vFXfcSRokxKo5RW0tRE1qEK0NKw9606 rigid:7fqj2Gju3X4HbV0gQNAzWx9cUhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6B0I6 uniprotkb:P19474 intact:EBI-4311651|uniprotkb:Q9NW76|uniprotkb:B3KPC4|uniprotkb:Q9NT41|uniprotkb:Q0VF39|ensembl:ENSP00000334181|ensembl:ENSP00000460897|ensembl:ENSP00000482224 intact:EBI-81290|uniprotkb:Q96RF8|uniprotkb:Q5XPV5|ensembl:ENSP00000254436 psi-mi:kdm4d_human(display_long)|uniprotkb:KDM4D(gene name)|psi-mi:KDM4D(display_short)|uniprotkb:JHDM3D(gene name synonym)|uniprotkb:JMJD2D(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3D(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2D(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4D"(gene name synonym) psi-mi:ro52_human(display_long)|uniprotkb:TRIM21(gene name)|psi-mi:TRIM21(display_short)|uniprotkb:RNF81(gene name synonym)|uniprotkb:Sjoegren syndrome type A antigen(gene name synonym)|uniprotkb:"Ro(SS-A)"(gene name synonym)|uniprotkb:52 kDa ribonucleoprotein autoantigen Ro/SS-A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 21(gene name synonym)|uniprotkb:RING finger protein 81(gene name synonym)|uniprotkb:52 kDa Ro protein(gene name synonym)|uniprotkb:RO52(gene name synonym)|uniprotkb:SSA1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM21(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480104|imex:IM-26985-481 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060509.2|rcsb pdb:5PI6|rcsb pdb:5PI7|rcsb pdb:5PI8|rcsb pdb:5PI9|rcsb pdb:5PIA|rcsb pdb:5PIB|rcsb pdb:5PIC|rcsb pdb:5PID|rcsb pdb:5PIE|rcsb pdb:5PIF|rcsb pdb:5PIG|rcsb pdb:5PIH|rcsb pdb:5PII|rcsb pdb:5PIJ|rcsb pdb:5PIK|rcsb pdb:5PIL|rcsb pdb:5PIM|rcsb pdb:5PIN|rcsb pdb:5PIO|rcsb pdb:5PIP|rcsb pdb:5PIQ|rcsb pdb:5PIR|rcsb pdb:5PIS|rcsb pdb:5PIT|rcsb pdb:5PIU|rcsb pdb:5PIV|rcsb pdb:5PIW|rcsb pdb:5PIX|rcsb pdb:5PIY|rcsb pdb:5PIZ|rcsb pdb:5PJ0|rcsb pdb:5PI5|rcsb pdb:5PJ1|rcsb pdb:5PJ2|rcsb pdb:5PJ3|rcsb pdb:5PJ4|rcsb pdb:5PJ6|rcsb pdb:5PJ7|rcsb pdb:5PJ8|rcsb pdb:5PJ9|rcsb pdb:5PJA|rcsb pdb:5PJB|rcsb pdb:5PJC|rcsb pdb:5PJD|rcsb pdb:5PJE|rcsb pdb:5PJF|rcsb pdb:5PJG|rcsb pdb:5PJ5|rcsb pdb:5PJH|rcsb pdb:5PJI|rcsb pdb:5PJJ|rcsb pdb:5PJK|rcsb pdb:5PJL|rcsb pdb:5PJM|rcsb pdb:5PJN|rcsb pdb:5PJO|rcsb pdb:5PJP|rcsb pdb:5PJQ|rcsb pdb:5PJR|rcsb pdb:5PJS|rcsb pdb:6ETT|rcsb pdb:6ETU|rcsb pdb:5PJT|rcsb pdb:6ETV|rcsb pdb:6ETW|rcsb pdb:6F5Q|rcsb pdb:6F5R|rcsb pdb:6F5S|rcsb pdb:6F5T|rcsb pdb:6H0W|rcsb pdb:6H0X|rcsb pdb:6H0Y|rcsb pdb:6H0Z|rcsb pdb:6H10|rcsb pdb:6H11|reactome:R-HSA-3214842|ensembl:ENSG00000186280(gene)|ensembl:ENST00000335080(transcript)|ensembl:ENST00000536741(transcript)|ensembl:ENST00000610872(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|rcsb pdb:5PJV|rcsb pdb:5PJW|rcsb pdb:5PJX|rcsb pdb:5PJY|rcsb pdb:5PJZ|rcsb pdb:5PK0|rcsb pdb:5PK1|rcsb pdb:5PK2|rcsb pdb:5PJU|rcsb pdb:5PK3|rcsb pdb:5PK4|rcsb pdb:5PK5|rcsb pdb:5PK6|rcsb pdb:5PK7|rcsb pdb:5PK8|rcsb pdb:5PK9|rcsb pdb:5PKA|rcsb pdb:5PKB|rcsb pdb:5PKC|rcsb pdb:5PKD|rcsb pdb:5PKE|rcsb pdb:5PKF|rcsb pdb:5PKG|rcsb pdb:5PKH|rcsb pdb:5PKI|rcsb pdb:5PKJ|rcsb pdb:5PKK|rcsb pdb:5PKL|rcsb pdb:5PKM|rcsb pdb:5PKN|rcsb pdb:5PKO|rcsb pdb:5PKP|rcsb pdb:5PKQ|rcsb pdb:5PKR|rcsb pdb:5PKS|rcsb pdb:5PKT|rcsb pdb:5PKU|rcsb pdb:5PKV|rcsb pdb:5PKW|rcsb pdb:5PKX|rcsb pdb:5PKY|rcsb pdb:5PKZ|rcsb pdb:5PL0|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072562"(blood microparticle)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|mint:Q6B0I6|rcsb pdb:3DXT|rcsb pdb:3DXU|rcsb pdb:4D6Q|rcsb pdb:4D6R|rcsb pdb:4D6S|rcsb pdb:4HON|rcsb pdb:5PL2|rcsb pdb:5PL3|rcsb pdb:5PL1|rcsb pdb:5PL4|rcsb pdb:5PL5|rcsb pdb:5PL6|rcsb pdb:5PL7|rcsb pdb:5PL8|rcsb pdb:5PL9|rcsb pdb:5PLA|rcsb pdb:5PLB|rcsb pdb:5PLC|rcsb pdb:5PLD|rcsb pdb:5PLE|rcsb pdb:5PLF|rcsb pdb:5PLG|rcsb pdb:5PLH|rcsb pdb:5PLI|rcsb pdb:5PLJ|rcsb pdb:5PLK|rcsb pdb:5PLL|rcsb pdb:5PLM|rcsb pdb:5PLN|rcsb pdb:5PLO|rcsb pdb:5PLP|rcsb pdb:5PLQ|rcsb pdb:5PLR|rcsb pdb:5PLS|rcsb pdb:5F5A|rcsb pdb:5F5C|rcsb pdb:5FP4|rcsb pdb:5FP7|rcsb pdb:5FP8|rcsb pdb:5FP9|rcsb pdb:5FPA|rcsb pdb:5FPB|rcsb pdb:5PH0|rcsb pdb:5PH1|rcsb pdb:5PH2|rcsb pdb:5PH3|rcsb pdb:5PH4|rcsb pdb:4HOO|rcsb pdb:5PH5|rcsb pdb:5PH6|rcsb pdb:5PH7|rcsb pdb:5PH8|rcsb pdb:5PH9|rcsb pdb:5PHA|rcsb pdb:5PHB|rcsb pdb:5PHC|rcsb pdb:5PHD|rcsb pdb:5PHE|rcsb pdb:5PLU|rcsb pdb:5PLV|rcsb pdb:5PLW|rcsb pdb:5PLX|rcsb pdb:5PLY|rcsb pdb:5PLZ|rcsb pdb:5PM0|rcsb pdb:5PM1|rcsb pdb:5PM2|rcsb pdb:5PM3|rcsb pdb:5PM4|rcsb pdb:5PM5|rcsb pdb:5PM6|rcsb pdb:5PM7|rcsb pdb:5PM8|rcsb pdb:5PM9|rcsb pdb:5PMA|rcsb pdb:5PMB|rcsb pdb:5PMC|rcsb pdb:5PMD|rcsb pdb:5PME|rcsb pdb:5PMF|rcsb pdb:5PMG|rcsb pdb:5PMH|rcsb pdb:5PMI|rcsb pdb:5PMJ|rcsb pdb:5PMK|rcsb pdb:5PML|rcsb pdb:5PMM|rcsb pdb:5PMN|rcsb pdb:5PMO|rcsb pdb:5PMP|rcsb pdb:5PMQ|rcsb pdb:5PMR|rcsb pdb:5PMS|rcsb pdb:5PMT|rcsb pdb:5PMU|rcsb pdb:5PMV|rcsb pdb:5PMW|rcsb pdb:5PMX|rcsb pdb:5PMY|rcsb pdb:5PMZ|rcsb pdb:5PN0|rcsb pdb:5PN1|rcsb pdb:5PN2|rcsb pdb:5PN3|rcsb pdb:5PN4|rcsb pdb:5PN5|rcsb pdb:5PN6|rcsb pdb:5PN7|rcsb pdb:5PN8|rcsb pdb:5PN9|rcsb pdb:5PNA|rcsb pdb:5PNB|rcsb pdb:5PNC|rcsb pdb:5PND|rcsb pdb:5PNE|rcsb pdb:5PNF|rcsb pdb:5PNG|rcsb pdb:5PNH|rcsb pdb:5PNI|rcsb pdb:5PNJ|rcsb pdb:5PNK|rcsb pdb:5PNL|rcsb pdb:5PNM|rcsb pdb:5PLT|rcsb pdb:5PNN|rcsb pdb:5PNO|rcsb pdb:5PNP|rcsb pdb:5PNQ|rcsb pdb:5PNR|rcsb pdb:5PNS|rcsb pdb:5PNU|rcsb pdb:5PNV|rcsb pdb:5PNW|rcsb pdb:6ETE|rcsb pdb:6ETG|rcsb pdb:6ETS|rcsb pdb:5PHJ|rcsb pdb:5PHK|rcsb pdb:5PHL|rcsb pdb:5PHM|rcsb pdb:5PHN|rcsb pdb:5PHO|rcsb pdb:5PHP|rcsb pdb:5PHQ|rcsb pdb:5PHR|rcsb pdb:5PHS|rcsb pdb:5PHT|rcsb pdb:5PHU|rcsb pdb:5PHV|rcsb pdb:5PHF|rcsb pdb:5PHG|rcsb pdb:5PHH|rcsb pdb:5PHI|rcsb pdb:5PHW|rcsb pdb:5PHX|rcsb pdb:5PHY|rcsb pdb:5PHZ|rcsb pdb:5PI0|rcsb pdb:5PI1|rcsb pdb:5PI2|rcsb pdb:5PI3|rcsb pdb:5PI4|dip:DIP-29606N refseq:NP_003132.2|go:"GO:0019901"(protein kinase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031648"(protein destabilization)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032479"(regulation of type I interferon production)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045087"(innate immune response)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0090086"(negative regulation of protein deubiquitination)|ensembl:ENSG00000132109(gene)|ensembl:ENST00000254436(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000932"(P-body)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR020457|interpro:IPR035831|interpro:IPR043136|mint:P19474|rcsb pdb:2IWG|rcsb pdb:5JPX|rcsb pdb:5OLM|rcsb pdb:6FGA|rcsb pdb:6S53|rcsb pdb:7BBD|reactome:R-HSA-1834941|reactome:R-HSA-3134975|reactome:R-HSA-877300|reactome:R-HSA-983168|go:"GO:1902187"|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003613(U box)|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like) - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:svQfKWBCSAPSGFAV5YPZXFvcqkk9606 rogid:/9rpwdudXQWv8z8JLmRecXf3YQM9606 rigid:7fqj2Gju3X4HbV0gQNAzWx9cUhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6B0I6 uniprotkb:P34932 intact:EBI-4311651|uniprotkb:Q9NW76|uniprotkb:B3KPC4|uniprotkb:Q9NT41|uniprotkb:Q0VF39|ensembl:ENSP00000334181|ensembl:ENSP00000460897|ensembl:ENSP00000482224 intact:EBI-356933|uniprotkb:O95756|uniprotkb:Q2TAL4|uniprotkb:Q9BUK9|ensembl:ENSP00000302961 psi-mi:kdm4d_human(display_long)|uniprotkb:KDM4D(gene name)|psi-mi:KDM4D(display_short)|uniprotkb:JHDM3D(gene name synonym)|uniprotkb:JMJD2D(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3D(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2D(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4D"(gene name synonym) psi-mi:hsp74_human(display_long)|uniprotkb:HSPA4(gene name)|psi-mi:HSPA4(display_short)|uniprotkb:APG2(gene name synonym)|uniprotkb:Heat shock 70-related protein APG-2(gene name synonym)|uniprotkb:HSP70RY(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480104|imex:IM-26985-481 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060509.2|rcsb pdb:5PI6|rcsb pdb:5PI7|rcsb pdb:5PI8|rcsb pdb:5PI9|rcsb pdb:5PIA|rcsb pdb:5PIB|rcsb pdb:5PIC|rcsb pdb:5PID|rcsb pdb:5PIE|rcsb pdb:5PIF|rcsb pdb:5PIG|rcsb pdb:5PIH|rcsb pdb:5PII|rcsb pdb:5PIJ|rcsb pdb:5PIK|rcsb pdb:5PIL|rcsb pdb:5PIM|rcsb pdb:5PIN|rcsb pdb:5PIO|rcsb pdb:5PIP|rcsb pdb:5PIQ|rcsb pdb:5PIR|rcsb pdb:5PIS|rcsb pdb:5PIT|rcsb pdb:5PIU|rcsb pdb:5PIV|rcsb pdb:5PIW|rcsb pdb:5PIX|rcsb pdb:5PIY|rcsb pdb:5PIZ|rcsb pdb:5PJ0|rcsb pdb:5PI5|rcsb pdb:5PJ1|rcsb pdb:5PJ2|rcsb pdb:5PJ3|rcsb pdb:5PJ4|rcsb pdb:5PJ6|rcsb pdb:5PJ7|rcsb pdb:5PJ8|rcsb pdb:5PJ9|rcsb pdb:5PJA|rcsb pdb:5PJB|rcsb pdb:5PJC|rcsb pdb:5PJD|rcsb pdb:5PJE|rcsb pdb:5PJF|rcsb pdb:5PJG|rcsb pdb:5PJ5|rcsb pdb:5PJH|rcsb pdb:5PJI|rcsb pdb:5PJJ|rcsb pdb:5PJK|rcsb pdb:5PJL|rcsb pdb:5PJM|rcsb pdb:5PJN|rcsb pdb:5PJO|rcsb pdb:5PJP|rcsb pdb:5PJQ|rcsb pdb:5PJR|rcsb pdb:5PJS|rcsb pdb:6ETT|rcsb pdb:6ETU|rcsb pdb:5PJT|rcsb pdb:6ETV|rcsb pdb:6ETW|rcsb pdb:6F5Q|rcsb pdb:6F5R|rcsb pdb:6F5S|rcsb pdb:6F5T|rcsb pdb:6H0W|rcsb pdb:6H0X|rcsb pdb:6H0Y|rcsb pdb:6H0Z|rcsb pdb:6H10|rcsb pdb:6H11|reactome:R-HSA-3214842|ensembl:ENSG00000186280(gene)|ensembl:ENST00000335080(transcript)|ensembl:ENST00000536741(transcript)|ensembl:ENST00000610872(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|rcsb pdb:5PJV|rcsb pdb:5PJW|rcsb pdb:5PJX|rcsb pdb:5PJY|rcsb pdb:5PJZ|rcsb pdb:5PK0|rcsb pdb:5PK1|rcsb pdb:5PK2|rcsb pdb:5PJU|rcsb pdb:5PK3|rcsb pdb:5PK4|rcsb pdb:5PK5|rcsb pdb:5PK6|rcsb pdb:5PK7|rcsb pdb:5PK8|rcsb pdb:5PK9|rcsb pdb:5PKA|rcsb pdb:5PKB|rcsb pdb:5PKC|rcsb pdb:5PKD|rcsb pdb:5PKE|rcsb pdb:5PKF|rcsb pdb:5PKG|rcsb pdb:5PKH|rcsb pdb:5PKI|rcsb pdb:5PKJ|rcsb pdb:5PKK|rcsb pdb:5PKL|rcsb pdb:5PKM|rcsb pdb:5PKN|rcsb pdb:5PKO|rcsb pdb:5PKP|rcsb pdb:5PKQ|rcsb pdb:5PKR|rcsb pdb:5PKS|rcsb pdb:5PKT|rcsb pdb:5PKU|rcsb pdb:5PKV|rcsb pdb:5PKW|rcsb pdb:5PKX|rcsb pdb:5PKY|rcsb pdb:5PKZ|rcsb pdb:5PL0|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072562"(blood microparticle)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|mint:Q6B0I6|rcsb pdb:3DXT|rcsb pdb:3DXU|rcsb pdb:4D6Q|rcsb pdb:4D6R|rcsb pdb:4D6S|rcsb pdb:4HON|rcsb pdb:5PL2|rcsb pdb:5PL3|rcsb pdb:5PL1|rcsb pdb:5PL4|rcsb pdb:5PL5|rcsb pdb:5PL6|rcsb pdb:5PL7|rcsb pdb:5PL8|rcsb pdb:5PL9|rcsb pdb:5PLA|rcsb pdb:5PLB|rcsb pdb:5PLC|rcsb pdb:5PLD|rcsb pdb:5PLE|rcsb pdb:5PLF|rcsb pdb:5PLG|rcsb pdb:5PLH|rcsb pdb:5PLI|rcsb pdb:5PLJ|rcsb pdb:5PLK|rcsb pdb:5PLL|rcsb pdb:5PLM|rcsb pdb:5PLN|rcsb pdb:5PLO|rcsb pdb:5PLP|rcsb pdb:5PLQ|rcsb pdb:5PLR|rcsb pdb:5PLS|rcsb pdb:5F5A|rcsb pdb:5F5C|rcsb pdb:5FP4|rcsb pdb:5FP7|rcsb pdb:5FP8|rcsb pdb:5FP9|rcsb pdb:5FPA|rcsb pdb:5FPB|rcsb pdb:5PH0|rcsb pdb:5PH1|rcsb pdb:5PH2|rcsb pdb:5PH3|rcsb pdb:5PH4|rcsb pdb:4HOO|rcsb pdb:5PH5|rcsb pdb:5PH6|rcsb pdb:5PH7|rcsb pdb:5PH8|rcsb pdb:5PH9|rcsb pdb:5PHA|rcsb pdb:5PHB|rcsb pdb:5PHC|rcsb pdb:5PHD|rcsb pdb:5PHE|rcsb pdb:5PLU|rcsb pdb:5PLV|rcsb pdb:5PLW|rcsb pdb:5PLX|rcsb pdb:5PLY|rcsb pdb:5PLZ|rcsb pdb:5PM0|rcsb pdb:5PM1|rcsb pdb:5PM2|rcsb pdb:5PM3|rcsb pdb:5PM4|rcsb pdb:5PM5|rcsb pdb:5PM6|rcsb pdb:5PM7|rcsb pdb:5PM8|rcsb pdb:5PM9|rcsb pdb:5PMA|rcsb pdb:5PMB|rcsb pdb:5PMC|rcsb pdb:5PMD|rcsb pdb:5PME|rcsb pdb:5PMF|rcsb pdb:5PMG|rcsb pdb:5PMH|rcsb pdb:5PMI|rcsb pdb:5PMJ|rcsb pdb:5PMK|rcsb pdb:5PML|rcsb pdb:5PMM|rcsb pdb:5PMN|rcsb pdb:5PMO|rcsb pdb:5PMP|rcsb pdb:5PMQ|rcsb pdb:5PMR|rcsb pdb:5PMS|rcsb pdb:5PMT|rcsb pdb:5PMU|rcsb pdb:5PMV|rcsb pdb:5PMW|rcsb pdb:5PMX|rcsb pdb:5PMY|rcsb pdb:5PMZ|rcsb pdb:5PN0|rcsb pdb:5PN1|rcsb pdb:5PN2|rcsb pdb:5PN3|rcsb pdb:5PN4|rcsb pdb:5PN5|rcsb pdb:5PN6|rcsb pdb:5PN7|rcsb pdb:5PN8|rcsb pdb:5PN9|rcsb pdb:5PNA|rcsb pdb:5PNB|rcsb pdb:5PNC|rcsb pdb:5PND|rcsb pdb:5PNE|rcsb pdb:5PNF|rcsb pdb:5PNG|rcsb pdb:5PNH|rcsb pdb:5PNI|rcsb pdb:5PNJ|rcsb pdb:5PNK|rcsb pdb:5PNL|rcsb pdb:5PNM|rcsb pdb:5PLT|rcsb pdb:5PNN|rcsb pdb:5PNO|rcsb pdb:5PNP|rcsb pdb:5PNQ|rcsb pdb:5PNR|rcsb pdb:5PNS|rcsb pdb:5PNU|rcsb pdb:5PNV|rcsb pdb:5PNW|rcsb pdb:6ETE|rcsb pdb:6ETG|rcsb pdb:6ETS|rcsb pdb:5PHJ|rcsb pdb:5PHK|rcsb pdb:5PHL|rcsb pdb:5PHM|rcsb pdb:5PHN|rcsb pdb:5PHO|rcsb pdb:5PHP|rcsb pdb:5PHQ|rcsb pdb:5PHR|rcsb pdb:5PHS|rcsb pdb:5PHT|rcsb pdb:5PHU|rcsb pdb:5PHV|rcsb pdb:5PHF|rcsb pdb:5PHG|rcsb pdb:5PHH|rcsb pdb:5PHI|rcsb pdb:5PHW|rcsb pdb:5PHX|rcsb pdb:5PHY|rcsb pdb:5PHZ|rcsb pdb:5PI0|rcsb pdb:5PI1|rcsb pdb:5PI2|rcsb pdb:5PI3|rcsb pdb:5PI4|dip:DIP-29606N refseq:NP_002145.3|dip:DIP-460N|ensembl:ENSG00000170606(gene)|ensembl:ENST00000304858(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0045040"(protein insertion into mitochondrial outer membrane)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042052|interpro:IPR043129|mint:P34932|reactome:R-HSA-3371453 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:svQfKWBCSAPSGFAV5YPZXFvcqkk9606 rogid:4OkTlG9p3IQQBYloiuHS8+t13TM9606 rigid:7fqj2Gju3X4HbV0gQNAzWx9cUhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6B0I6 uniprotkb:Q96I25 intact:EBI-4311651|uniprotkb:Q9NW76|uniprotkb:B3KPC4|uniprotkb:Q9NT41|uniprotkb:Q0VF39|ensembl:ENSP00000334181|ensembl:ENSP00000460897|ensembl:ENSP00000482224 intact:EBI-740272|uniprotkb:Q96GY6|ensembl:ENSP00000369218|ensembl:ENSP00000388638 psi-mi:kdm4d_human(display_long)|uniprotkb:KDM4D(gene name)|psi-mi:KDM4D(display_short)|uniprotkb:JHDM3D(gene name synonym)|uniprotkb:JMJD2D(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3D(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2D(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4D"(gene name synonym) psi-mi:spf45_human(display_long)|uniprotkb:45 kDa-splicing factor(gene name synonym)|uniprotkb:RNA-binding motif protein 17(gene name synonym)|uniprotkb:RBM17(gene name)|psi-mi:RBM17(display_short)|uniprotkb:SPF45(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480104|imex:IM-26985-481 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060509.2|rcsb pdb:5PI6|rcsb pdb:5PI7|rcsb pdb:5PI8|rcsb pdb:5PI9|rcsb pdb:5PIA|rcsb pdb:5PIB|rcsb pdb:5PIC|rcsb pdb:5PID|rcsb pdb:5PIE|rcsb pdb:5PIF|rcsb pdb:5PIG|rcsb pdb:5PIH|rcsb pdb:5PII|rcsb pdb:5PIJ|rcsb pdb:5PIK|rcsb pdb:5PIL|rcsb pdb:5PIM|rcsb pdb:5PIN|rcsb pdb:5PIO|rcsb pdb:5PIP|rcsb pdb:5PIQ|rcsb pdb:5PIR|rcsb pdb:5PIS|rcsb pdb:5PIT|rcsb pdb:5PIU|rcsb pdb:5PIV|rcsb pdb:5PIW|rcsb pdb:5PIX|rcsb pdb:5PIY|rcsb pdb:5PIZ|rcsb pdb:5PJ0|rcsb pdb:5PI5|rcsb pdb:5PJ1|rcsb pdb:5PJ2|rcsb pdb:5PJ3|rcsb pdb:5PJ4|rcsb pdb:5PJ6|rcsb pdb:5PJ7|rcsb pdb:5PJ8|rcsb pdb:5PJ9|rcsb pdb:5PJA|rcsb pdb:5PJB|rcsb pdb:5PJC|rcsb pdb:5PJD|rcsb pdb:5PJE|rcsb pdb:5PJF|rcsb pdb:5PJG|rcsb pdb:5PJ5|rcsb pdb:5PJH|rcsb pdb:5PJI|rcsb pdb:5PJJ|rcsb pdb:5PJK|rcsb pdb:5PJL|rcsb pdb:5PJM|rcsb pdb:5PJN|rcsb pdb:5PJO|rcsb pdb:5PJP|rcsb pdb:5PJQ|rcsb pdb:5PJR|rcsb pdb:5PJS|rcsb pdb:6ETT|rcsb pdb:6ETU|rcsb pdb:5PJT|rcsb pdb:6ETV|rcsb pdb:6ETW|rcsb pdb:6F5Q|rcsb pdb:6F5R|rcsb pdb:6F5S|rcsb pdb:6F5T|rcsb pdb:6H0W|rcsb pdb:6H0X|rcsb pdb:6H0Y|rcsb pdb:6H0Z|rcsb pdb:6H10|rcsb pdb:6H11|reactome:R-HSA-3214842|ensembl:ENSG00000186280(gene)|ensembl:ENST00000335080(transcript)|ensembl:ENST00000536741(transcript)|ensembl:ENST00000610872(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|rcsb pdb:5PJV|rcsb pdb:5PJW|rcsb pdb:5PJX|rcsb pdb:5PJY|rcsb pdb:5PJZ|rcsb pdb:5PK0|rcsb pdb:5PK1|rcsb pdb:5PK2|rcsb pdb:5PJU|rcsb pdb:5PK3|rcsb pdb:5PK4|rcsb pdb:5PK5|rcsb pdb:5PK6|rcsb pdb:5PK7|rcsb pdb:5PK8|rcsb pdb:5PK9|rcsb pdb:5PKA|rcsb pdb:5PKB|rcsb pdb:5PKC|rcsb pdb:5PKD|rcsb pdb:5PKE|rcsb pdb:5PKF|rcsb pdb:5PKG|rcsb pdb:5PKH|rcsb pdb:5PKI|rcsb pdb:5PKJ|rcsb pdb:5PKK|rcsb pdb:5PKL|rcsb pdb:5PKM|rcsb pdb:5PKN|rcsb pdb:5PKO|rcsb pdb:5PKP|rcsb pdb:5PKQ|rcsb pdb:5PKR|rcsb pdb:5PKS|rcsb pdb:5PKT|rcsb pdb:5PKU|rcsb pdb:5PKV|rcsb pdb:5PKW|rcsb pdb:5PKX|rcsb pdb:5PKY|rcsb pdb:5PKZ|rcsb pdb:5PL0|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072562"(blood microparticle)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|mint:Q6B0I6|rcsb pdb:3DXT|rcsb pdb:3DXU|rcsb pdb:4D6Q|rcsb pdb:4D6R|rcsb pdb:4D6S|rcsb pdb:4HON|rcsb pdb:5PL2|rcsb pdb:5PL3|rcsb pdb:5PL1|rcsb pdb:5PL4|rcsb pdb:5PL5|rcsb pdb:5PL6|rcsb pdb:5PL7|rcsb pdb:5PL8|rcsb pdb:5PL9|rcsb pdb:5PLA|rcsb pdb:5PLB|rcsb pdb:5PLC|rcsb pdb:5PLD|rcsb pdb:5PLE|rcsb pdb:5PLF|rcsb pdb:5PLG|rcsb pdb:5PLH|rcsb pdb:5PLI|rcsb pdb:5PLJ|rcsb pdb:5PLK|rcsb pdb:5PLL|rcsb pdb:5PLM|rcsb pdb:5PLN|rcsb pdb:5PLO|rcsb pdb:5PLP|rcsb pdb:5PLQ|rcsb pdb:5PLR|rcsb pdb:5PLS|rcsb pdb:5F5A|rcsb pdb:5F5C|rcsb pdb:5FP4|rcsb pdb:5FP7|rcsb pdb:5FP8|rcsb pdb:5FP9|rcsb pdb:5FPA|rcsb pdb:5FPB|rcsb pdb:5PH0|rcsb pdb:5PH1|rcsb pdb:5PH2|rcsb pdb:5PH3|rcsb pdb:5PH4|rcsb pdb:4HOO|rcsb pdb:5PH5|rcsb pdb:5PH6|rcsb pdb:5PH7|rcsb pdb:5PH8|rcsb pdb:5PH9|rcsb pdb:5PHA|rcsb pdb:5PHB|rcsb pdb:5PHC|rcsb pdb:5PHD|rcsb pdb:5PHE|rcsb pdb:5PLU|rcsb pdb:5PLV|rcsb pdb:5PLW|rcsb pdb:5PLX|rcsb pdb:5PLY|rcsb pdb:5PLZ|rcsb pdb:5PM0|rcsb pdb:5PM1|rcsb pdb:5PM2|rcsb pdb:5PM3|rcsb pdb:5PM4|rcsb pdb:5PM5|rcsb pdb:5PM6|rcsb pdb:5PM7|rcsb pdb:5PM8|rcsb pdb:5PM9|rcsb pdb:5PMA|rcsb pdb:5PMB|rcsb pdb:5PMC|rcsb pdb:5PMD|rcsb pdb:5PME|rcsb pdb:5PMF|rcsb pdb:5PMG|rcsb pdb:5PMH|rcsb pdb:5PMI|rcsb pdb:5PMJ|rcsb pdb:5PMK|rcsb pdb:5PML|rcsb pdb:5PMM|rcsb pdb:5PMN|rcsb pdb:5PMO|rcsb pdb:5PMP|rcsb pdb:5PMQ|rcsb pdb:5PMR|rcsb pdb:5PMS|rcsb pdb:5PMT|rcsb pdb:5PMU|rcsb pdb:5PMV|rcsb pdb:5PMW|rcsb pdb:5PMX|rcsb pdb:5PMY|rcsb pdb:5PMZ|rcsb pdb:5PN0|rcsb pdb:5PN1|rcsb pdb:5PN2|rcsb pdb:5PN3|rcsb pdb:5PN4|rcsb pdb:5PN5|rcsb pdb:5PN6|rcsb pdb:5PN7|rcsb pdb:5PN8|rcsb pdb:5PN9|rcsb pdb:5PNA|rcsb pdb:5PNB|rcsb pdb:5PNC|rcsb pdb:5PND|rcsb pdb:5PNE|rcsb pdb:5PNF|rcsb pdb:5PNG|rcsb pdb:5PNH|rcsb pdb:5PNI|rcsb pdb:5PNJ|rcsb pdb:5PNK|rcsb pdb:5PNL|rcsb pdb:5PNM|rcsb pdb:5PLT|rcsb pdb:5PNN|rcsb pdb:5PNO|rcsb pdb:5PNP|rcsb pdb:5PNQ|rcsb pdb:5PNR|rcsb pdb:5PNS|rcsb pdb:5PNU|rcsb pdb:5PNV|rcsb pdb:5PNW|rcsb pdb:6ETE|rcsb pdb:6ETG|rcsb pdb:6ETS|rcsb pdb:5PHJ|rcsb pdb:5PHK|rcsb pdb:5PHL|rcsb pdb:5PHM|rcsb pdb:5PHN|rcsb pdb:5PHO|rcsb pdb:5PHP|rcsb pdb:5PHQ|rcsb pdb:5PHR|rcsb pdb:5PHS|rcsb pdb:5PHT|rcsb pdb:5PHU|rcsb pdb:5PHV|rcsb pdb:5PHF|rcsb pdb:5PHG|rcsb pdb:5PHH|rcsb pdb:5PHI|rcsb pdb:5PHW|rcsb pdb:5PHX|rcsb pdb:5PHY|rcsb pdb:5PHZ|rcsb pdb:5PI0|rcsb pdb:5PI1|rcsb pdb:5PI2|rcsb pdb:5PI3|rcsb pdb:5PI4|dip:DIP-29606N refseq:NP_001139019.1|refseq:NP_116294.1|ensembl:ENSG00000134453(gene)|ensembl:ENST00000379888(transcript)|ensembl:ENST00000446108(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0043484"(regulation of RNA splicing)|interpro:IPR000467(D111/G-patch)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034653|interpro:IPR035979|interpro:IPR040052|mint:Q96I25|rcsb pdb:2PE8|rcsb pdb:2PEH|rcsb pdb:5LSO|rcsb pdb:6HIP|reactome:R-HSA-72163|dip:DIP-29409N - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:svQfKWBCSAPSGFAV5YPZXFvcqkk9606 rogid:Vhyfu0XQEzUpy7smEsSHj1s5O+49606 rigid:7fqj2Gju3X4HbV0gQNAzWx9cUhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6B0I6 uniprotkb:O75934 intact:EBI-4311651|uniprotkb:Q9NW76|uniprotkb:B3KPC4|uniprotkb:Q9NT41|uniprotkb:Q0VF39|ensembl:ENSP00000334181|ensembl:ENSP00000460897|ensembl:ENSP00000482224 intact:EBI-1050106|uniprotkb:Q6FGS0|ensembl:ENSP00000358554 psi-mi:kdm4d_human(display_long)|uniprotkb:KDM4D(gene name)|psi-mi:KDM4D(display_short)|uniprotkb:JHDM3D(gene name synonym)|uniprotkb:JMJD2D(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3D(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2D(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4D"(gene name synonym) psi-mi:spf27_human(display_long)|uniprotkb:Spliceosome-associated protein SPF 27(gene name synonym)|uniprotkb:Breast carcinoma-amplified sequence 2(gene name synonym)|uniprotkb:DNA amplified in mammary carcinoma 1 protein(gene name synonym)|uniprotkb:BCAS2(gene name)|psi-mi:BCAS2(display_short)|uniprotkb:DAM1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480104|imex:IM-26985-481 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060509.2|rcsb pdb:5PI6|rcsb pdb:5PI7|rcsb pdb:5PI8|rcsb pdb:5PI9|rcsb pdb:5PIA|rcsb pdb:5PIB|rcsb pdb:5PIC|rcsb pdb:5PID|rcsb pdb:5PIE|rcsb pdb:5PIF|rcsb pdb:5PIG|rcsb pdb:5PIH|rcsb pdb:5PII|rcsb pdb:5PIJ|rcsb pdb:5PIK|rcsb pdb:5PIL|rcsb pdb:5PIM|rcsb pdb:5PIN|rcsb pdb:5PIO|rcsb pdb:5PIP|rcsb pdb:5PIQ|rcsb pdb:5PIR|rcsb pdb:5PIS|rcsb pdb:5PIT|rcsb pdb:5PIU|rcsb pdb:5PIV|rcsb pdb:5PIW|rcsb pdb:5PIX|rcsb pdb:5PIY|rcsb pdb:5PIZ|rcsb pdb:5PJ0|rcsb pdb:5PI5|rcsb pdb:5PJ1|rcsb pdb:5PJ2|rcsb pdb:5PJ3|rcsb pdb:5PJ4|rcsb pdb:5PJ6|rcsb pdb:5PJ7|rcsb pdb:5PJ8|rcsb pdb:5PJ9|rcsb pdb:5PJA|rcsb pdb:5PJB|rcsb pdb:5PJC|rcsb pdb:5PJD|rcsb pdb:5PJE|rcsb pdb:5PJF|rcsb pdb:5PJG|rcsb pdb:5PJ5|rcsb pdb:5PJH|rcsb pdb:5PJI|rcsb pdb:5PJJ|rcsb pdb:5PJK|rcsb pdb:5PJL|rcsb pdb:5PJM|rcsb pdb:5PJN|rcsb pdb:5PJO|rcsb pdb:5PJP|rcsb pdb:5PJQ|rcsb pdb:5PJR|rcsb pdb:5PJS|rcsb pdb:6ETT|rcsb pdb:6ETU|rcsb pdb:5PJT|rcsb pdb:6ETV|rcsb pdb:6ETW|rcsb pdb:6F5Q|rcsb pdb:6F5R|rcsb pdb:6F5S|rcsb pdb:6F5T|rcsb pdb:6H0W|rcsb pdb:6H0X|rcsb pdb:6H0Y|rcsb pdb:6H0Z|rcsb pdb:6H10|rcsb pdb:6H11|reactome:R-HSA-3214842|ensembl:ENSG00000186280(gene)|ensembl:ENST00000335080(transcript)|ensembl:ENST00000536741(transcript)|ensembl:ENST00000610872(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|rcsb pdb:5PJV|rcsb pdb:5PJW|rcsb pdb:5PJX|rcsb pdb:5PJY|rcsb pdb:5PJZ|rcsb pdb:5PK0|rcsb pdb:5PK1|rcsb pdb:5PK2|rcsb pdb:5PJU|rcsb pdb:5PK3|rcsb pdb:5PK4|rcsb pdb:5PK5|rcsb pdb:5PK6|rcsb pdb:5PK7|rcsb pdb:5PK8|rcsb pdb:5PK9|rcsb pdb:5PKA|rcsb pdb:5PKB|rcsb pdb:5PKC|rcsb pdb:5PKD|rcsb pdb:5PKE|rcsb pdb:5PKF|rcsb pdb:5PKG|rcsb pdb:5PKH|rcsb pdb:5PKI|rcsb pdb:5PKJ|rcsb pdb:5PKK|rcsb pdb:5PKL|rcsb pdb:5PKM|rcsb pdb:5PKN|rcsb pdb:5PKO|rcsb pdb:5PKP|rcsb pdb:5PKQ|rcsb pdb:5PKR|rcsb pdb:5PKS|rcsb pdb:5PKT|rcsb pdb:5PKU|rcsb pdb:5PKV|rcsb pdb:5PKW|rcsb pdb:5PKX|rcsb pdb:5PKY|rcsb pdb:5PKZ|rcsb pdb:5PL0|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072562"(blood microparticle)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|mint:Q6B0I6|rcsb pdb:3DXT|rcsb pdb:3DXU|rcsb pdb:4D6Q|rcsb pdb:4D6R|rcsb pdb:4D6S|rcsb pdb:4HON|rcsb pdb:5PL2|rcsb pdb:5PL3|rcsb pdb:5PL1|rcsb pdb:5PL4|rcsb pdb:5PL5|rcsb pdb:5PL6|rcsb pdb:5PL7|rcsb pdb:5PL8|rcsb pdb:5PL9|rcsb pdb:5PLA|rcsb pdb:5PLB|rcsb pdb:5PLC|rcsb pdb:5PLD|rcsb pdb:5PLE|rcsb pdb:5PLF|rcsb pdb:5PLG|rcsb pdb:5PLH|rcsb pdb:5PLI|rcsb pdb:5PLJ|rcsb pdb:5PLK|rcsb pdb:5PLL|rcsb pdb:5PLM|rcsb pdb:5PLN|rcsb pdb:5PLO|rcsb pdb:5PLP|rcsb pdb:5PLQ|rcsb pdb:5PLR|rcsb pdb:5PLS|rcsb pdb:5F5A|rcsb pdb:5F5C|rcsb pdb:5FP4|rcsb pdb:5FP7|rcsb pdb:5FP8|rcsb pdb:5FP9|rcsb pdb:5FPA|rcsb pdb:5FPB|rcsb pdb:5PH0|rcsb pdb:5PH1|rcsb pdb:5PH2|rcsb pdb:5PH3|rcsb pdb:5PH4|rcsb pdb:4HOO|rcsb pdb:5PH5|rcsb pdb:5PH6|rcsb pdb:5PH7|rcsb pdb:5PH8|rcsb pdb:5PH9|rcsb pdb:5PHA|rcsb pdb:5PHB|rcsb pdb:5PHC|rcsb pdb:5PHD|rcsb pdb:5PHE|rcsb pdb:5PLU|rcsb pdb:5PLV|rcsb pdb:5PLW|rcsb pdb:5PLX|rcsb pdb:5PLY|rcsb pdb:5PLZ|rcsb pdb:5PM0|rcsb pdb:5PM1|rcsb pdb:5PM2|rcsb pdb:5PM3|rcsb pdb:5PM4|rcsb pdb:5PM5|rcsb pdb:5PM6|rcsb pdb:5PM7|rcsb pdb:5PM8|rcsb pdb:5PM9|rcsb pdb:5PMA|rcsb pdb:5PMB|rcsb pdb:5PMC|rcsb pdb:5PMD|rcsb pdb:5PME|rcsb pdb:5PMF|rcsb pdb:5PMG|rcsb pdb:5PMH|rcsb pdb:5PMI|rcsb pdb:5PMJ|rcsb pdb:5PMK|rcsb pdb:5PML|rcsb pdb:5PMM|rcsb pdb:5PMN|rcsb pdb:5PMO|rcsb pdb:5PMP|rcsb pdb:5PMQ|rcsb pdb:5PMR|rcsb pdb:5PMS|rcsb pdb:5PMT|rcsb pdb:5PMU|rcsb pdb:5PMV|rcsb pdb:5PMW|rcsb pdb:5PMX|rcsb pdb:5PMY|rcsb pdb:5PMZ|rcsb pdb:5PN0|rcsb pdb:5PN1|rcsb pdb:5PN2|rcsb pdb:5PN3|rcsb pdb:5PN4|rcsb pdb:5PN5|rcsb pdb:5PN6|rcsb pdb:5PN7|rcsb pdb:5PN8|rcsb pdb:5PN9|rcsb pdb:5PNA|rcsb pdb:5PNB|rcsb pdb:5PNC|rcsb pdb:5PND|rcsb pdb:5PNE|rcsb pdb:5PNF|rcsb pdb:5PNG|rcsb pdb:5PNH|rcsb pdb:5PNI|rcsb pdb:5PNJ|rcsb pdb:5PNK|rcsb pdb:5PNL|rcsb pdb:5PNM|rcsb pdb:5PLT|rcsb pdb:5PNN|rcsb pdb:5PNO|rcsb pdb:5PNP|rcsb pdb:5PNQ|rcsb pdb:5PNR|rcsb pdb:5PNS|rcsb pdb:5PNU|rcsb pdb:5PNV|rcsb pdb:5PNW|rcsb pdb:6ETE|rcsb pdb:6ETG|rcsb pdb:6ETS|rcsb pdb:5PHJ|rcsb pdb:5PHK|rcsb pdb:5PHL|rcsb pdb:5PHM|rcsb pdb:5PHN|rcsb pdb:5PHO|rcsb pdb:5PHP|rcsb pdb:5PHQ|rcsb pdb:5PHR|rcsb pdb:5PHS|rcsb pdb:5PHT|rcsb pdb:5PHU|rcsb pdb:5PHV|rcsb pdb:5PHF|rcsb pdb:5PHG|rcsb pdb:5PHH|rcsb pdb:5PHI|rcsb pdb:5PHW|rcsb pdb:5PHX|rcsb pdb:5PHY|rcsb pdb:5PHZ|rcsb pdb:5PI0|rcsb pdb:5PI1|rcsb pdb:5PI2|rcsb pdb:5PI3|rcsb pdb:5PI4|dip:DIP-29606N refseq:NP_005863.1|ensembl:ENSG00000116752(gene)|ensembl:ENST00000369541(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005813"(centrosome)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR008409(Breast carcinoma amplified sequence 2)|mint:O75934|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|reactome:R-HSA-72163 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:svQfKWBCSAPSGFAV5YPZXFvcqkk9606 rogid:yBhnwZOlEWsxnRIeuf/Z85O/QSQ9606 rigid:7fqj2Gju3X4HbV0gQNAzWx9cUhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6B0I6 uniprotkb:P09661 intact:EBI-4311651|uniprotkb:Q9NW76|uniprotkb:B3KPC4|uniprotkb:Q9NT41|uniprotkb:Q0VF39|ensembl:ENSP00000334181|ensembl:ENSP00000460897|ensembl:ENSP00000482224 intact:EBI-876439|uniprotkb:Q8TBD2|uniprotkb:B2R5I6|ensembl:ENSP00000254193 psi-mi:kdm4d_human(display_long)|uniprotkb:KDM4D(gene name)|psi-mi:KDM4D(display_short)|uniprotkb:JHDM3D(gene name synonym)|uniprotkb:JMJD2D(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3D(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2D(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4D"(gene name synonym) psi-mi:ru2a_human(display_long)|uniprotkb:SNRPA1(gene name)|psi-mi:SNRPA1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480104|imex:IM-26985-481 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060509.2|rcsb pdb:5PI6|rcsb pdb:5PI7|rcsb pdb:5PI8|rcsb pdb:5PI9|rcsb pdb:5PIA|rcsb pdb:5PIB|rcsb pdb:5PIC|rcsb pdb:5PID|rcsb pdb:5PIE|rcsb pdb:5PIF|rcsb pdb:5PIG|rcsb pdb:5PIH|rcsb pdb:5PII|rcsb pdb:5PIJ|rcsb pdb:5PIK|rcsb pdb:5PIL|rcsb pdb:5PIM|rcsb pdb:5PIN|rcsb pdb:5PIO|rcsb pdb:5PIP|rcsb pdb:5PIQ|rcsb pdb:5PIR|rcsb pdb:5PIS|rcsb pdb:5PIT|rcsb pdb:5PIU|rcsb pdb:5PIV|rcsb pdb:5PIW|rcsb pdb:5PIX|rcsb pdb:5PIY|rcsb pdb:5PIZ|rcsb pdb:5PJ0|rcsb pdb:5PI5|rcsb pdb:5PJ1|rcsb pdb:5PJ2|rcsb pdb:5PJ3|rcsb pdb:5PJ4|rcsb pdb:5PJ6|rcsb pdb:5PJ7|rcsb pdb:5PJ8|rcsb pdb:5PJ9|rcsb pdb:5PJA|rcsb pdb:5PJB|rcsb pdb:5PJC|rcsb pdb:5PJD|rcsb pdb:5PJE|rcsb pdb:5PJF|rcsb pdb:5PJG|rcsb pdb:5PJ5|rcsb pdb:5PJH|rcsb pdb:5PJI|rcsb pdb:5PJJ|rcsb pdb:5PJK|rcsb pdb:5PJL|rcsb pdb:5PJM|rcsb pdb:5PJN|rcsb pdb:5PJO|rcsb pdb:5PJP|rcsb pdb:5PJQ|rcsb pdb:5PJR|rcsb pdb:5PJS|rcsb pdb:6ETT|rcsb pdb:6ETU|rcsb pdb:5PJT|rcsb pdb:6ETV|rcsb pdb:6ETW|rcsb pdb:6F5Q|rcsb pdb:6F5R|rcsb pdb:6F5S|rcsb pdb:6F5T|rcsb pdb:6H0W|rcsb pdb:6H0X|rcsb pdb:6H0Y|rcsb pdb:6H0Z|rcsb pdb:6H10|rcsb pdb:6H11|reactome:R-HSA-3214842|ensembl:ENSG00000186280(gene)|ensembl:ENST00000335080(transcript)|ensembl:ENST00000536741(transcript)|ensembl:ENST00000610872(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|rcsb pdb:5PJV|rcsb pdb:5PJW|rcsb pdb:5PJX|rcsb pdb:5PJY|rcsb pdb:5PJZ|rcsb pdb:5PK0|rcsb pdb:5PK1|rcsb pdb:5PK2|rcsb pdb:5PJU|rcsb pdb:5PK3|rcsb pdb:5PK4|rcsb pdb:5PK5|rcsb pdb:5PK6|rcsb pdb:5PK7|rcsb pdb:5PK8|rcsb pdb:5PK9|rcsb pdb:5PKA|rcsb pdb:5PKB|rcsb pdb:5PKC|rcsb pdb:5PKD|rcsb pdb:5PKE|rcsb pdb:5PKF|rcsb pdb:5PKG|rcsb pdb:5PKH|rcsb pdb:5PKI|rcsb pdb:5PKJ|rcsb pdb:5PKK|rcsb pdb:5PKL|rcsb pdb:5PKM|rcsb pdb:5PKN|rcsb pdb:5PKO|rcsb pdb:5PKP|rcsb pdb:5PKQ|rcsb pdb:5PKR|rcsb pdb:5PKS|rcsb pdb:5PKT|rcsb pdb:5PKU|rcsb pdb:5PKV|rcsb pdb:5PKW|rcsb pdb:5PKX|rcsb pdb:5PKY|rcsb pdb:5PKZ|rcsb pdb:5PL0|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072562"(blood microparticle)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|mint:Q6B0I6|rcsb pdb:3DXT|rcsb pdb:3DXU|rcsb pdb:4D6Q|rcsb pdb:4D6R|rcsb pdb:4D6S|rcsb pdb:4HON|rcsb pdb:5PL2|rcsb pdb:5PL3|rcsb pdb:5PL1|rcsb pdb:5PL4|rcsb pdb:5PL5|rcsb pdb:5PL6|rcsb pdb:5PL7|rcsb pdb:5PL8|rcsb pdb:5PL9|rcsb pdb:5PLA|rcsb pdb:5PLB|rcsb pdb:5PLC|rcsb pdb:5PLD|rcsb pdb:5PLE|rcsb pdb:5PLF|rcsb pdb:5PLG|rcsb pdb:5PLH|rcsb pdb:5PLI|rcsb pdb:5PLJ|rcsb pdb:5PLK|rcsb pdb:5PLL|rcsb pdb:5PLM|rcsb pdb:5PLN|rcsb pdb:5PLO|rcsb pdb:5PLP|rcsb pdb:5PLQ|rcsb pdb:5PLR|rcsb pdb:5PLS|rcsb pdb:5F5A|rcsb pdb:5F5C|rcsb pdb:5FP4|rcsb pdb:5FP7|rcsb pdb:5FP8|rcsb pdb:5FP9|rcsb pdb:5FPA|rcsb pdb:5FPB|rcsb pdb:5PH0|rcsb pdb:5PH1|rcsb pdb:5PH2|rcsb pdb:5PH3|rcsb pdb:5PH4|rcsb pdb:4HOO|rcsb pdb:5PH5|rcsb pdb:5PH6|rcsb pdb:5PH7|rcsb pdb:5PH8|rcsb pdb:5PH9|rcsb pdb:5PHA|rcsb pdb:5PHB|rcsb pdb:5PHC|rcsb pdb:5PHD|rcsb pdb:5PHE|rcsb pdb:5PLU|rcsb pdb:5PLV|rcsb pdb:5PLW|rcsb pdb:5PLX|rcsb pdb:5PLY|rcsb pdb:5PLZ|rcsb pdb:5PM0|rcsb pdb:5PM1|rcsb pdb:5PM2|rcsb pdb:5PM3|rcsb pdb:5PM4|rcsb pdb:5PM5|rcsb pdb:5PM6|rcsb pdb:5PM7|rcsb pdb:5PM8|rcsb pdb:5PM9|rcsb pdb:5PMA|rcsb pdb:5PMB|rcsb pdb:5PMC|rcsb pdb:5PMD|rcsb pdb:5PME|rcsb pdb:5PMF|rcsb pdb:5PMG|rcsb pdb:5PMH|rcsb pdb:5PMI|rcsb pdb:5PMJ|rcsb pdb:5PMK|rcsb pdb:5PML|rcsb pdb:5PMM|rcsb pdb:5PMN|rcsb pdb:5PMO|rcsb pdb:5PMP|rcsb pdb:5PMQ|rcsb pdb:5PMR|rcsb pdb:5PMS|rcsb pdb:5PMT|rcsb pdb:5PMU|rcsb pdb:5PMV|rcsb pdb:5PMW|rcsb pdb:5PMX|rcsb pdb:5PMY|rcsb pdb:5PMZ|rcsb pdb:5PN0|rcsb pdb:5PN1|rcsb pdb:5PN2|rcsb pdb:5PN3|rcsb pdb:5PN4|rcsb pdb:5PN5|rcsb pdb:5PN6|rcsb pdb:5PN7|rcsb pdb:5PN8|rcsb pdb:5PN9|rcsb pdb:5PNA|rcsb pdb:5PNB|rcsb pdb:5PNC|rcsb pdb:5PND|rcsb pdb:5PNE|rcsb pdb:5PNF|rcsb pdb:5PNG|rcsb pdb:5PNH|rcsb pdb:5PNI|rcsb pdb:5PNJ|rcsb pdb:5PNK|rcsb pdb:5PNL|rcsb pdb:5PNM|rcsb pdb:5PLT|rcsb pdb:5PNN|rcsb pdb:5PNO|rcsb pdb:5PNP|rcsb pdb:5PNQ|rcsb pdb:5PNR|rcsb pdb:5PNS|rcsb pdb:5PNU|rcsb pdb:5PNV|rcsb pdb:5PNW|rcsb pdb:6ETE|rcsb pdb:6ETG|rcsb pdb:6ETS|rcsb pdb:5PHJ|rcsb pdb:5PHK|rcsb pdb:5PHL|rcsb pdb:5PHM|rcsb pdb:5PHN|rcsb pdb:5PHO|rcsb pdb:5PHP|rcsb pdb:5PHQ|rcsb pdb:5PHR|rcsb pdb:5PHS|rcsb pdb:5PHT|rcsb pdb:5PHU|rcsb pdb:5PHV|rcsb pdb:5PHF|rcsb pdb:5PHG|rcsb pdb:5PHH|rcsb pdb:5PHI|rcsb pdb:5PHW|rcsb pdb:5PHX|rcsb pdb:5PHY|rcsb pdb:5PHZ|rcsb pdb:5PI0|rcsb pdb:5PI1|rcsb pdb:5PI2|rcsb pdb:5PI3|rcsb pdb:5PI4|dip:DIP-29606N refseq:NP_003081.2|dip:DIP-625N|ensembl:ENSG00000131876(gene)|ensembl:ENST00000254193(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR032675|interpro:IPR044640|mint:P09661|rcsb pdb:1A9N|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|reactome:R-HSA-72163|reactome:R-HSA-8950505 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:svQfKWBCSAPSGFAV5YPZXFvcqkk9606 rogid:tmZyAPCvMg34GY4kVc6NcnycOeE9606 rigid:7fqj2Gju3X4HbV0gQNAzWx9cUhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6B0I6 uniprotkb:O43809 intact:EBI-4311651|uniprotkb:Q9NW76|uniprotkb:B3KPC4|uniprotkb:Q9NT41|uniprotkb:Q0VF39|ensembl:ENSP00000334181|ensembl:ENSP00000460897|ensembl:ENSP00000482224 intact:EBI-355720|uniprotkb:Q6IB85|uniprotkb:Q6NE84|ensembl:ENSP00000300291 psi-mi:kdm4d_human(display_long)|uniprotkb:KDM4D(gene name)|psi-mi:KDM4D(display_short)|uniprotkb:JHDM3D(gene name synonym)|uniprotkb:JMJD2D(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3D(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2D(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4D"(gene name synonym) psi-mi:cpsf5_human(display_long)|uniprotkb:NUDT21(gene name)|psi-mi:NUDT21(display_short)|uniprotkb:CFIM25(gene name synonym)|uniprotkb:CPSF25(gene name synonym)|uniprotkb:CPSF5(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 25 kDa subunit(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 21(gene name synonym)|uniprotkb:Cleavage factor Im complex 25 kDa subunit(gene name synonym)|uniprotkb:Nudix hydrolase 21(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 68 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480104|imex:IM-26985-481 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060509.2|rcsb pdb:5PI6|rcsb pdb:5PI7|rcsb pdb:5PI8|rcsb pdb:5PI9|rcsb pdb:5PIA|rcsb pdb:5PIB|rcsb pdb:5PIC|rcsb pdb:5PID|rcsb pdb:5PIE|rcsb pdb:5PIF|rcsb pdb:5PIG|rcsb pdb:5PIH|rcsb pdb:5PII|rcsb pdb:5PIJ|rcsb pdb:5PIK|rcsb pdb:5PIL|rcsb pdb:5PIM|rcsb pdb:5PIN|rcsb pdb:5PIO|rcsb pdb:5PIP|rcsb pdb:5PIQ|rcsb pdb:5PIR|rcsb pdb:5PIS|rcsb pdb:5PIT|rcsb pdb:5PIU|rcsb pdb:5PIV|rcsb pdb:5PIW|rcsb pdb:5PIX|rcsb pdb:5PIY|rcsb pdb:5PIZ|rcsb pdb:5PJ0|rcsb pdb:5PI5|rcsb pdb:5PJ1|rcsb pdb:5PJ2|rcsb pdb:5PJ3|rcsb pdb:5PJ4|rcsb pdb:5PJ6|rcsb pdb:5PJ7|rcsb pdb:5PJ8|rcsb pdb:5PJ9|rcsb pdb:5PJA|rcsb pdb:5PJB|rcsb pdb:5PJC|rcsb pdb:5PJD|rcsb pdb:5PJE|rcsb pdb:5PJF|rcsb pdb:5PJG|rcsb pdb:5PJ5|rcsb pdb:5PJH|rcsb pdb:5PJI|rcsb pdb:5PJJ|rcsb pdb:5PJK|rcsb pdb:5PJL|rcsb pdb:5PJM|rcsb pdb:5PJN|rcsb pdb:5PJO|rcsb pdb:5PJP|rcsb pdb:5PJQ|rcsb pdb:5PJR|rcsb pdb:5PJS|rcsb pdb:6ETT|rcsb pdb:6ETU|rcsb pdb:5PJT|rcsb pdb:6ETV|rcsb pdb:6ETW|rcsb pdb:6F5Q|rcsb pdb:6F5R|rcsb pdb:6F5S|rcsb pdb:6F5T|rcsb pdb:6H0W|rcsb pdb:6H0X|rcsb pdb:6H0Y|rcsb pdb:6H0Z|rcsb pdb:6H10|rcsb pdb:6H11|reactome:R-HSA-3214842|ensembl:ENSG00000186280(gene)|ensembl:ENST00000335080(transcript)|ensembl:ENST00000536741(transcript)|ensembl:ENST00000610872(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|rcsb pdb:5PJV|rcsb pdb:5PJW|rcsb pdb:5PJX|rcsb pdb:5PJY|rcsb pdb:5PJZ|rcsb pdb:5PK0|rcsb pdb:5PK1|rcsb pdb:5PK2|rcsb pdb:5PJU|rcsb pdb:5PK3|rcsb pdb:5PK4|rcsb pdb:5PK5|rcsb pdb:5PK6|rcsb pdb:5PK7|rcsb pdb:5PK8|rcsb pdb:5PK9|rcsb pdb:5PKA|rcsb pdb:5PKB|rcsb pdb:5PKC|rcsb pdb:5PKD|rcsb pdb:5PKE|rcsb pdb:5PKF|rcsb pdb:5PKG|rcsb pdb:5PKH|rcsb pdb:5PKI|rcsb pdb:5PKJ|rcsb pdb:5PKK|rcsb pdb:5PKL|rcsb pdb:5PKM|rcsb pdb:5PKN|rcsb pdb:5PKO|rcsb pdb:5PKP|rcsb pdb:5PKQ|rcsb pdb:5PKR|rcsb pdb:5PKS|rcsb pdb:5PKT|rcsb pdb:5PKU|rcsb pdb:5PKV|rcsb pdb:5PKW|rcsb pdb:5PKX|rcsb pdb:5PKY|rcsb pdb:5PKZ|rcsb pdb:5PL0|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072562"(blood microparticle)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|mint:Q6B0I6|rcsb pdb:3DXT|rcsb pdb:3DXU|rcsb pdb:4D6Q|rcsb pdb:4D6R|rcsb pdb:4D6S|rcsb pdb:4HON|rcsb pdb:5PL2|rcsb pdb:5PL3|rcsb pdb:5PL1|rcsb pdb:5PL4|rcsb pdb:5PL5|rcsb pdb:5PL6|rcsb pdb:5PL7|rcsb pdb:5PL8|rcsb pdb:5PL9|rcsb pdb:5PLA|rcsb pdb:5PLB|rcsb pdb:5PLC|rcsb pdb:5PLD|rcsb pdb:5PLE|rcsb pdb:5PLF|rcsb pdb:5PLG|rcsb pdb:5PLH|rcsb pdb:5PLI|rcsb pdb:5PLJ|rcsb pdb:5PLK|rcsb pdb:5PLL|rcsb pdb:5PLM|rcsb pdb:5PLN|rcsb pdb:5PLO|rcsb pdb:5PLP|rcsb pdb:5PLQ|rcsb pdb:5PLR|rcsb pdb:5PLS|rcsb pdb:5F5A|rcsb pdb:5F5C|rcsb pdb:5FP4|rcsb pdb:5FP7|rcsb pdb:5FP8|rcsb pdb:5FP9|rcsb pdb:5FPA|rcsb pdb:5FPB|rcsb pdb:5PH0|rcsb pdb:5PH1|rcsb pdb:5PH2|rcsb pdb:5PH3|rcsb pdb:5PH4|rcsb pdb:4HOO|rcsb pdb:5PH5|rcsb pdb:5PH6|rcsb pdb:5PH7|rcsb pdb:5PH8|rcsb pdb:5PH9|rcsb pdb:5PHA|rcsb pdb:5PHB|rcsb pdb:5PHC|rcsb pdb:5PHD|rcsb pdb:5PHE|rcsb pdb:5PLU|rcsb pdb:5PLV|rcsb pdb:5PLW|rcsb pdb:5PLX|rcsb pdb:5PLY|rcsb pdb:5PLZ|rcsb pdb:5PM0|rcsb pdb:5PM1|rcsb pdb:5PM2|rcsb pdb:5PM3|rcsb pdb:5PM4|rcsb pdb:5PM5|rcsb pdb:5PM6|rcsb pdb:5PM7|rcsb pdb:5PM8|rcsb pdb:5PM9|rcsb pdb:5PMA|rcsb pdb:5PMB|rcsb pdb:5PMC|rcsb pdb:5PMD|rcsb pdb:5PME|rcsb pdb:5PMF|rcsb pdb:5PMG|rcsb pdb:5PMH|rcsb pdb:5PMI|rcsb pdb:5PMJ|rcsb pdb:5PMK|rcsb pdb:5PML|rcsb pdb:5PMM|rcsb pdb:5PMN|rcsb pdb:5PMO|rcsb pdb:5PMP|rcsb pdb:5PMQ|rcsb pdb:5PMR|rcsb pdb:5PMS|rcsb pdb:5PMT|rcsb pdb:5PMU|rcsb pdb:5PMV|rcsb pdb:5PMW|rcsb pdb:5PMX|rcsb pdb:5PMY|rcsb pdb:5PMZ|rcsb pdb:5PN0|rcsb pdb:5PN1|rcsb pdb:5PN2|rcsb pdb:5PN3|rcsb pdb:5PN4|rcsb pdb:5PN5|rcsb pdb:5PN6|rcsb pdb:5PN7|rcsb pdb:5PN8|rcsb pdb:5PN9|rcsb pdb:5PNA|rcsb pdb:5PNB|rcsb pdb:5PNC|rcsb pdb:5PND|rcsb pdb:5PNE|rcsb pdb:5PNF|rcsb pdb:5PNG|rcsb pdb:5PNH|rcsb pdb:5PNI|rcsb pdb:5PNJ|rcsb pdb:5PNK|rcsb pdb:5PNL|rcsb pdb:5PNM|rcsb pdb:5PLT|rcsb pdb:5PNN|rcsb pdb:5PNO|rcsb pdb:5PNP|rcsb pdb:5PNQ|rcsb pdb:5PNR|rcsb pdb:5PNS|rcsb pdb:5PNU|rcsb pdb:5PNV|rcsb pdb:5PNW|rcsb pdb:6ETE|rcsb pdb:6ETG|rcsb pdb:6ETS|rcsb pdb:5PHJ|rcsb pdb:5PHK|rcsb pdb:5PHL|rcsb pdb:5PHM|rcsb pdb:5PHN|rcsb pdb:5PHO|rcsb pdb:5PHP|rcsb pdb:5PHQ|rcsb pdb:5PHR|rcsb pdb:5PHS|rcsb pdb:5PHT|rcsb pdb:5PHU|rcsb pdb:5PHV|rcsb pdb:5PHF|rcsb pdb:5PHG|rcsb pdb:5PHH|rcsb pdb:5PHI|rcsb pdb:5PHW|rcsb pdb:5PHX|rcsb pdb:5PHY|rcsb pdb:5PHZ|rcsb pdb:5PI0|rcsb pdb:5PI1|rcsb pdb:5PI2|rcsb pdb:5PI3|rcsb pdb:5PI4|dip:DIP-29606N refseq:NP_008937.1|ensembl:ENSG00000167005(gene)|ensembl:ENST00000300291(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006397"(mRNA processing)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0031439"(positive regulation of mRNA cleavage)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042382"(paraspeckles)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|go:"GO:1900365"(positive regulation of mRNA polyadenylation)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:2000738"(positive regulation of stem cell differentiation)|go:"GO:2000975"(positive regulation of pro-B cell differentiation)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR016706(Cleavage and polyadenylation specificity factor, 25 kDa subunit)|mint:O43809|rcsb pdb:2CL3|rcsb pdb:2J8Q|rcsb pdb:3BAP|rcsb pdb:3BHO|rcsb pdb:3MDG|rcsb pdb:3MDI|rcsb pdb:3N9U|rcsb pdb:3P5T|rcsb pdb:3P6Y|rcsb pdb:3Q2S|rcsb pdb:3Q2T|rcsb pdb:5R4P|rcsb pdb:5R4Q|rcsb pdb:5R4R|rcsb pdb:5R4S|rcsb pdb:5R4T|rcsb pdb:5R4U|rcsb pdb:5R64|rcsb pdb:5R65|rcsb pdb:5R66|rcsb pdb:5R67|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|dip:DIP-42502N - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:svQfKWBCSAPSGFAV5YPZXFvcqkk9606 rogid:Acad4mYVuS+Eox+X2CH8PYUkGAA9606 rigid:7fqj2Gju3X4HbV0gQNAzWx9cUhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6B0I6 uniprotkb:Q12874 intact:EBI-4311651|uniprotkb:Q9NW76|uniprotkb:B3KPC4|uniprotkb:Q9NT41|uniprotkb:Q0VF39|ensembl:ENSP00000334181|ensembl:ENSP00000460897|ensembl:ENSP00000482224 intact:EBI-1051880|uniprotkb:Q15460|uniprotkb:Q5VT87|uniprotkb:D3DPT5|ensembl:ENSP00000362110 psi-mi:kdm4d_human(display_long)|uniprotkb:KDM4D(gene name)|psi-mi:KDM4D(display_short)|uniprotkb:JHDM3D(gene name synonym)|uniprotkb:JMJD2D(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3D(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2D(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4D"(gene name synonym) psi-mi:sf3a3_human(display_long)|uniprotkb:Spliceosome-associated protein 61(gene name synonym)|uniprotkb:SF3a60(gene name synonym)|uniprotkb:SF3A3(gene name)|psi-mi:SF3A3(display_short)|uniprotkb:SAP61(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480104|imex:IM-26985-481 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060509.2|rcsb pdb:5PI6|rcsb pdb:5PI7|rcsb pdb:5PI8|rcsb pdb:5PI9|rcsb pdb:5PIA|rcsb pdb:5PIB|rcsb pdb:5PIC|rcsb pdb:5PID|rcsb pdb:5PIE|rcsb pdb:5PIF|rcsb pdb:5PIG|rcsb pdb:5PIH|rcsb pdb:5PII|rcsb pdb:5PIJ|rcsb pdb:5PIK|rcsb pdb:5PIL|rcsb pdb:5PIM|rcsb pdb:5PIN|rcsb pdb:5PIO|rcsb pdb:5PIP|rcsb pdb:5PIQ|rcsb pdb:5PIR|rcsb pdb:5PIS|rcsb pdb:5PIT|rcsb pdb:5PIU|rcsb pdb:5PIV|rcsb pdb:5PIW|rcsb pdb:5PIX|rcsb pdb:5PIY|rcsb pdb:5PIZ|rcsb pdb:5PJ0|rcsb pdb:5PI5|rcsb pdb:5PJ1|rcsb pdb:5PJ2|rcsb pdb:5PJ3|rcsb pdb:5PJ4|rcsb pdb:5PJ6|rcsb pdb:5PJ7|rcsb pdb:5PJ8|rcsb pdb:5PJ9|rcsb pdb:5PJA|rcsb pdb:5PJB|rcsb pdb:5PJC|rcsb pdb:5PJD|rcsb pdb:5PJE|rcsb pdb:5PJF|rcsb pdb:5PJG|rcsb pdb:5PJ5|rcsb pdb:5PJH|rcsb pdb:5PJI|rcsb pdb:5PJJ|rcsb pdb:5PJK|rcsb pdb:5PJL|rcsb pdb:5PJM|rcsb pdb:5PJN|rcsb pdb:5PJO|rcsb pdb:5PJP|rcsb pdb:5PJQ|rcsb pdb:5PJR|rcsb pdb:5PJS|rcsb pdb:6ETT|rcsb pdb:6ETU|rcsb pdb:5PJT|rcsb pdb:6ETV|rcsb pdb:6ETW|rcsb pdb:6F5Q|rcsb pdb:6F5R|rcsb pdb:6F5S|rcsb pdb:6F5T|rcsb pdb:6H0W|rcsb pdb:6H0X|rcsb pdb:6H0Y|rcsb pdb:6H0Z|rcsb pdb:6H10|rcsb pdb:6H11|reactome:R-HSA-3214842|ensembl:ENSG00000186280(gene)|ensembl:ENST00000335080(transcript)|ensembl:ENST00000536741(transcript)|ensembl:ENST00000610872(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|rcsb pdb:5PJV|rcsb pdb:5PJW|rcsb pdb:5PJX|rcsb pdb:5PJY|rcsb pdb:5PJZ|rcsb pdb:5PK0|rcsb pdb:5PK1|rcsb pdb:5PK2|rcsb pdb:5PJU|rcsb pdb:5PK3|rcsb pdb:5PK4|rcsb pdb:5PK5|rcsb pdb:5PK6|rcsb pdb:5PK7|rcsb pdb:5PK8|rcsb pdb:5PK9|rcsb pdb:5PKA|rcsb pdb:5PKB|rcsb pdb:5PKC|rcsb pdb:5PKD|rcsb pdb:5PKE|rcsb pdb:5PKF|rcsb pdb:5PKG|rcsb pdb:5PKH|rcsb pdb:5PKI|rcsb pdb:5PKJ|rcsb pdb:5PKK|rcsb pdb:5PKL|rcsb pdb:5PKM|rcsb pdb:5PKN|rcsb pdb:5PKO|rcsb pdb:5PKP|rcsb pdb:5PKQ|rcsb pdb:5PKR|rcsb pdb:5PKS|rcsb pdb:5PKT|rcsb pdb:5PKU|rcsb pdb:5PKV|rcsb pdb:5PKW|rcsb pdb:5PKX|rcsb pdb:5PKY|rcsb pdb:5PKZ|rcsb pdb:5PL0|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072562"(blood microparticle)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|mint:Q6B0I6|rcsb pdb:3DXT|rcsb pdb:3DXU|rcsb pdb:4D6Q|rcsb pdb:4D6R|rcsb pdb:4D6S|rcsb pdb:4HON|rcsb pdb:5PL2|rcsb pdb:5PL3|rcsb pdb:5PL1|rcsb pdb:5PL4|rcsb pdb:5PL5|rcsb pdb:5PL6|rcsb pdb:5PL7|rcsb pdb:5PL8|rcsb pdb:5PL9|rcsb pdb:5PLA|rcsb pdb:5PLB|rcsb pdb:5PLC|rcsb pdb:5PLD|rcsb pdb:5PLE|rcsb pdb:5PLF|rcsb pdb:5PLG|rcsb pdb:5PLH|rcsb pdb:5PLI|rcsb pdb:5PLJ|rcsb pdb:5PLK|rcsb pdb:5PLL|rcsb pdb:5PLM|rcsb pdb:5PLN|rcsb pdb:5PLO|rcsb pdb:5PLP|rcsb pdb:5PLQ|rcsb pdb:5PLR|rcsb pdb:5PLS|rcsb pdb:5F5A|rcsb pdb:5F5C|rcsb pdb:5FP4|rcsb pdb:5FP7|rcsb pdb:5FP8|rcsb pdb:5FP9|rcsb pdb:5FPA|rcsb pdb:5FPB|rcsb pdb:5PH0|rcsb pdb:5PH1|rcsb pdb:5PH2|rcsb pdb:5PH3|rcsb pdb:5PH4|rcsb pdb:4HOO|rcsb pdb:5PH5|rcsb pdb:5PH6|rcsb pdb:5PH7|rcsb pdb:5PH8|rcsb pdb:5PH9|rcsb pdb:5PHA|rcsb pdb:5PHB|rcsb pdb:5PHC|rcsb pdb:5PHD|rcsb pdb:5PHE|rcsb pdb:5PLU|rcsb pdb:5PLV|rcsb pdb:5PLW|rcsb pdb:5PLX|rcsb pdb:5PLY|rcsb pdb:5PLZ|rcsb pdb:5PM0|rcsb pdb:5PM1|rcsb pdb:5PM2|rcsb pdb:5PM3|rcsb pdb:5PM4|rcsb pdb:5PM5|rcsb pdb:5PM6|rcsb pdb:5PM7|rcsb pdb:5PM8|rcsb pdb:5PM9|rcsb pdb:5PMA|rcsb pdb:5PMB|rcsb pdb:5PMC|rcsb pdb:5PMD|rcsb pdb:5PME|rcsb pdb:5PMF|rcsb pdb:5PMG|rcsb pdb:5PMH|rcsb pdb:5PMI|rcsb pdb:5PMJ|rcsb pdb:5PMK|rcsb pdb:5PML|rcsb pdb:5PMM|rcsb pdb:5PMN|rcsb pdb:5PMO|rcsb pdb:5PMP|rcsb pdb:5PMQ|rcsb pdb:5PMR|rcsb pdb:5PMS|rcsb pdb:5PMT|rcsb pdb:5PMU|rcsb pdb:5PMV|rcsb pdb:5PMW|rcsb pdb:5PMX|rcsb pdb:5PMY|rcsb pdb:5PMZ|rcsb pdb:5PN0|rcsb pdb:5PN1|rcsb pdb:5PN2|rcsb pdb:5PN3|rcsb pdb:5PN4|rcsb pdb:5PN5|rcsb pdb:5PN6|rcsb pdb:5PN7|rcsb pdb:5PN8|rcsb pdb:5PN9|rcsb pdb:5PNA|rcsb pdb:5PNB|rcsb pdb:5PNC|rcsb pdb:5PND|rcsb pdb:5PNE|rcsb pdb:5PNF|rcsb pdb:5PNG|rcsb pdb:5PNH|rcsb pdb:5PNI|rcsb pdb:5PNJ|rcsb pdb:5PNK|rcsb pdb:5PNL|rcsb pdb:5PNM|rcsb pdb:5PLT|rcsb pdb:5PNN|rcsb pdb:5PNO|rcsb pdb:5PNP|rcsb pdb:5PNQ|rcsb pdb:5PNR|rcsb pdb:5PNS|rcsb pdb:5PNU|rcsb pdb:5PNV|rcsb pdb:5PNW|rcsb pdb:6ETE|rcsb pdb:6ETG|rcsb pdb:6ETS|rcsb pdb:5PHJ|rcsb pdb:5PHK|rcsb pdb:5PHL|rcsb pdb:5PHM|rcsb pdb:5PHN|rcsb pdb:5PHO|rcsb pdb:5PHP|rcsb pdb:5PHQ|rcsb pdb:5PHR|rcsb pdb:5PHS|rcsb pdb:5PHT|rcsb pdb:5PHU|rcsb pdb:5PHV|rcsb pdb:5PHF|rcsb pdb:5PHG|rcsb pdb:5PHH|rcsb pdb:5PHI|rcsb pdb:5PHW|rcsb pdb:5PHX|rcsb pdb:5PHY|rcsb pdb:5PHZ|rcsb pdb:5PI0|rcsb pdb:5PI1|rcsb pdb:5PI2|rcsb pdb:5PI3|rcsb pdb:5PI4|dip:DIP-29606N refseq:NP_006793.1|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1903241"(U2-type prespliceosome assembly)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR021966|interpro:IPR024598|interpro:IPR031774|interpro:IPR031776|mint:Q12874|rcsb pdb:2DT7|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|go:"GO:0000389"(mRNA 3'-splice site recognition)|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|reactome:R-HSA-72163|rcsb pdb:6Y53|ensembl:ENSG00000183431(gene)|ensembl:ENST00000373019(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|dip:DIP-882N - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:svQfKWBCSAPSGFAV5YPZXFvcqkk9606 rogid:fNjNguUOXqApr46rOAEpTs2geqY9606 rigid:7fqj2Gju3X4HbV0gQNAzWx9cUhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6B0I6 uniprotkb:Q8N954 intact:EBI-4311651|uniprotkb:Q9NW76|uniprotkb:B3KPC4|uniprotkb:Q9NT41|uniprotkb:Q0VF39|ensembl:ENSP00000334181|ensembl:ENSP00000460897|ensembl:ENSP00000482224 intact:EBI-2555378|uniprotkb:B7Z2G4|uniprotkb:A8K0D9|uniprotkb:B8ZZ44|ensembl:ENSP00000386772|uniprotkb:A0A0A0MSF9 psi-mi:kdm4d_human(display_long)|uniprotkb:KDM4D(gene name)|psi-mi:KDM4D(display_short)|uniprotkb:JHDM3D(gene name synonym)|uniprotkb:JMJD2D(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3D(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2D(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4D"(gene name synonym) psi-mi:gpt11_human(display_long)|uniprotkb:GPATCH11(gene name)|psi-mi:GPATCH11(display_short)|uniprotkb:CCDC75(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 75(gene name synonym)|uniprotkb:CENP-Y(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480104|imex:IM-26985-481 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060509.2|rcsb pdb:5PI6|rcsb pdb:5PI7|rcsb pdb:5PI8|rcsb pdb:5PI9|rcsb pdb:5PIA|rcsb pdb:5PIB|rcsb pdb:5PIC|rcsb pdb:5PID|rcsb pdb:5PIE|rcsb pdb:5PIF|rcsb pdb:5PIG|rcsb pdb:5PIH|rcsb pdb:5PII|rcsb pdb:5PIJ|rcsb pdb:5PIK|rcsb pdb:5PIL|rcsb pdb:5PIM|rcsb pdb:5PIN|rcsb pdb:5PIO|rcsb pdb:5PIP|rcsb pdb:5PIQ|rcsb pdb:5PIR|rcsb pdb:5PIS|rcsb pdb:5PIT|rcsb pdb:5PIU|rcsb pdb:5PIV|rcsb pdb:5PIW|rcsb pdb:5PIX|rcsb pdb:5PIY|rcsb pdb:5PIZ|rcsb pdb:5PJ0|rcsb pdb:5PI5|rcsb pdb:5PJ1|rcsb pdb:5PJ2|rcsb pdb:5PJ3|rcsb pdb:5PJ4|rcsb pdb:5PJ6|rcsb pdb:5PJ7|rcsb pdb:5PJ8|rcsb pdb:5PJ9|rcsb pdb:5PJA|rcsb pdb:5PJB|rcsb pdb:5PJC|rcsb pdb:5PJD|rcsb pdb:5PJE|rcsb pdb:5PJF|rcsb pdb:5PJG|rcsb pdb:5PJ5|rcsb pdb:5PJH|rcsb pdb:5PJI|rcsb pdb:5PJJ|rcsb pdb:5PJK|rcsb pdb:5PJL|rcsb pdb:5PJM|rcsb pdb:5PJN|rcsb pdb:5PJO|rcsb pdb:5PJP|rcsb pdb:5PJQ|rcsb pdb:5PJR|rcsb pdb:5PJS|rcsb pdb:6ETT|rcsb pdb:6ETU|rcsb pdb:5PJT|rcsb pdb:6ETV|rcsb pdb:6ETW|rcsb pdb:6F5Q|rcsb pdb:6F5R|rcsb pdb:6F5S|rcsb pdb:6F5T|rcsb pdb:6H0W|rcsb pdb:6H0X|rcsb pdb:6H0Y|rcsb pdb:6H0Z|rcsb pdb:6H10|rcsb pdb:6H11|reactome:R-HSA-3214842|ensembl:ENSG00000186280(gene)|ensembl:ENST00000335080(transcript)|ensembl:ENST00000536741(transcript)|ensembl:ENST00000610872(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|rcsb pdb:5PJV|rcsb pdb:5PJW|rcsb pdb:5PJX|rcsb pdb:5PJY|rcsb pdb:5PJZ|rcsb pdb:5PK0|rcsb pdb:5PK1|rcsb pdb:5PK2|rcsb pdb:5PJU|rcsb pdb:5PK3|rcsb pdb:5PK4|rcsb pdb:5PK5|rcsb pdb:5PK6|rcsb pdb:5PK7|rcsb pdb:5PK8|rcsb pdb:5PK9|rcsb pdb:5PKA|rcsb pdb:5PKB|rcsb pdb:5PKC|rcsb pdb:5PKD|rcsb pdb:5PKE|rcsb pdb:5PKF|rcsb pdb:5PKG|rcsb pdb:5PKH|rcsb pdb:5PKI|rcsb pdb:5PKJ|rcsb pdb:5PKK|rcsb pdb:5PKL|rcsb pdb:5PKM|rcsb pdb:5PKN|rcsb pdb:5PKO|rcsb pdb:5PKP|rcsb pdb:5PKQ|rcsb pdb:5PKR|rcsb pdb:5PKS|rcsb pdb:5PKT|rcsb pdb:5PKU|rcsb pdb:5PKV|rcsb pdb:5PKW|rcsb pdb:5PKX|rcsb pdb:5PKY|rcsb pdb:5PKZ|rcsb pdb:5PL0|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072562"(blood microparticle)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|mint:Q6B0I6|rcsb pdb:3DXT|rcsb pdb:3DXU|rcsb pdb:4D6Q|rcsb pdb:4D6R|rcsb pdb:4D6S|rcsb pdb:4HON|rcsb pdb:5PL2|rcsb pdb:5PL3|rcsb pdb:5PL1|rcsb pdb:5PL4|rcsb pdb:5PL5|rcsb pdb:5PL6|rcsb pdb:5PL7|rcsb pdb:5PL8|rcsb pdb:5PL9|rcsb pdb:5PLA|rcsb pdb:5PLB|rcsb pdb:5PLC|rcsb pdb:5PLD|rcsb pdb:5PLE|rcsb pdb:5PLF|rcsb pdb:5PLG|rcsb pdb:5PLH|rcsb pdb:5PLI|rcsb pdb:5PLJ|rcsb pdb:5PLK|rcsb pdb:5PLL|rcsb pdb:5PLM|rcsb pdb:5PLN|rcsb pdb:5PLO|rcsb pdb:5PLP|rcsb pdb:5PLQ|rcsb pdb:5PLR|rcsb pdb:5PLS|rcsb pdb:5F5A|rcsb pdb:5F5C|rcsb pdb:5FP4|rcsb pdb:5FP7|rcsb pdb:5FP8|rcsb pdb:5FP9|rcsb pdb:5FPA|rcsb pdb:5FPB|rcsb pdb:5PH0|rcsb pdb:5PH1|rcsb pdb:5PH2|rcsb pdb:5PH3|rcsb pdb:5PH4|rcsb pdb:4HOO|rcsb pdb:5PH5|rcsb pdb:5PH6|rcsb pdb:5PH7|rcsb pdb:5PH8|rcsb pdb:5PH9|rcsb pdb:5PHA|rcsb pdb:5PHB|rcsb pdb:5PHC|rcsb pdb:5PHD|rcsb pdb:5PHE|rcsb pdb:5PLU|rcsb pdb:5PLV|rcsb pdb:5PLW|rcsb pdb:5PLX|rcsb pdb:5PLY|rcsb pdb:5PLZ|rcsb pdb:5PM0|rcsb pdb:5PM1|rcsb pdb:5PM2|rcsb pdb:5PM3|rcsb pdb:5PM4|rcsb pdb:5PM5|rcsb pdb:5PM6|rcsb pdb:5PM7|rcsb pdb:5PM8|rcsb pdb:5PM9|rcsb pdb:5PMA|rcsb pdb:5PMB|rcsb pdb:5PMC|rcsb pdb:5PMD|rcsb pdb:5PME|rcsb pdb:5PMF|rcsb pdb:5PMG|rcsb pdb:5PMH|rcsb pdb:5PMI|rcsb pdb:5PMJ|rcsb pdb:5PMK|rcsb pdb:5PML|rcsb pdb:5PMM|rcsb pdb:5PMN|rcsb pdb:5PMO|rcsb pdb:5PMP|rcsb pdb:5PMQ|rcsb pdb:5PMR|rcsb pdb:5PMS|rcsb pdb:5PMT|rcsb pdb:5PMU|rcsb pdb:5PMV|rcsb pdb:5PMW|rcsb pdb:5PMX|rcsb pdb:5PMY|rcsb pdb:5PMZ|rcsb pdb:5PN0|rcsb pdb:5PN1|rcsb pdb:5PN2|rcsb pdb:5PN3|rcsb pdb:5PN4|rcsb pdb:5PN5|rcsb pdb:5PN6|rcsb pdb:5PN7|rcsb pdb:5PN8|rcsb pdb:5PN9|rcsb pdb:5PNA|rcsb pdb:5PNB|rcsb pdb:5PNC|rcsb pdb:5PND|rcsb pdb:5PNE|rcsb pdb:5PNF|rcsb pdb:5PNG|rcsb pdb:5PNH|rcsb pdb:5PNI|rcsb pdb:5PNJ|rcsb pdb:5PNK|rcsb pdb:5PNL|rcsb pdb:5PNM|rcsb pdb:5PLT|rcsb pdb:5PNN|rcsb pdb:5PNO|rcsb pdb:5PNP|rcsb pdb:5PNQ|rcsb pdb:5PNR|rcsb pdb:5PNS|rcsb pdb:5PNU|rcsb pdb:5PNV|rcsb pdb:5PNW|rcsb pdb:6ETE|rcsb pdb:6ETG|rcsb pdb:6ETS|rcsb pdb:5PHJ|rcsb pdb:5PHK|rcsb pdb:5PHL|rcsb pdb:5PHM|rcsb pdb:5PHN|rcsb pdb:5PHO|rcsb pdb:5PHP|rcsb pdb:5PHQ|rcsb pdb:5PHR|rcsb pdb:5PHS|rcsb pdb:5PHT|rcsb pdb:5PHU|rcsb pdb:5PHV|rcsb pdb:5PHF|rcsb pdb:5PHG|rcsb pdb:5PHH|rcsb pdb:5PHI|rcsb pdb:5PHW|rcsb pdb:5PHX|rcsb pdb:5PHY|rcsb pdb:5PHZ|rcsb pdb:5PI0|rcsb pdb:5PI1|rcsb pdb:5PI2|rcsb pdb:5PI3|rcsb pdb:5PI4|dip:DIP-29606N ensembl:ENSG00000152133(gene)|ensembl:ENST00000409774(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003676"(nucleic acid binding)|interpro:IPR000467(D111/G-patch)|interpro:IPR025239|interpro:IPR039249|mint:Q8N954|refseq:NP_001309178.1|refseq:NP_001265434.1|refseq:NP_777591.3|refseq:XP_016859237.1 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:svQfKWBCSAPSGFAV5YPZXFvcqkk9606 rogid:SGJyGylFtt7YkAqS1DRW5y3Yo089606 rigid:7fqj2Gju3X4HbV0gQNAzWx9cUhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6B0I6 uniprotkb:A6NHR9 intact:EBI-4311651|uniprotkb:Q9NW76|uniprotkb:B3KPC4|uniprotkb:Q9NT41|uniprotkb:Q0VF39|ensembl:ENSP00000334181|ensembl:ENSP00000460897|ensembl:ENSP00000482224 intact:EBI-2801919|uniprotkb:O75141|uniprotkb:Q6AHX6|uniprotkb:Q9H6Q2|uniprotkb:Q6ZTQ8|intact:EBI-3192385|uniprotkb:Q9UG39|ensembl:ENSP00000326603 psi-mi:kdm4d_human(display_long)|uniprotkb:KDM4D(gene name)|psi-mi:KDM4D(display_short)|uniprotkb:JHDM3D(gene name synonym)|uniprotkb:JMJD2D(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3D(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2D(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4D"(gene name synonym) psi-mi:smhd1_human(display_long)|uniprotkb:KIAA0650(gene name synonym)|uniprotkb:SMCHD1(gene name)|psi-mi:SMCHD1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480104|imex:IM-26985-481 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060509.2|rcsb pdb:5PI6|rcsb pdb:5PI7|rcsb pdb:5PI8|rcsb pdb:5PI9|rcsb pdb:5PIA|rcsb pdb:5PIB|rcsb pdb:5PIC|rcsb pdb:5PID|rcsb pdb:5PIE|rcsb pdb:5PIF|rcsb pdb:5PIG|rcsb pdb:5PIH|rcsb pdb:5PII|rcsb pdb:5PIJ|rcsb pdb:5PIK|rcsb pdb:5PIL|rcsb pdb:5PIM|rcsb pdb:5PIN|rcsb pdb:5PIO|rcsb pdb:5PIP|rcsb pdb:5PIQ|rcsb pdb:5PIR|rcsb pdb:5PIS|rcsb pdb:5PIT|rcsb pdb:5PIU|rcsb pdb:5PIV|rcsb pdb:5PIW|rcsb pdb:5PIX|rcsb pdb:5PIY|rcsb pdb:5PIZ|rcsb pdb:5PJ0|rcsb pdb:5PI5|rcsb pdb:5PJ1|rcsb pdb:5PJ2|rcsb pdb:5PJ3|rcsb pdb:5PJ4|rcsb pdb:5PJ6|rcsb pdb:5PJ7|rcsb pdb:5PJ8|rcsb pdb:5PJ9|rcsb pdb:5PJA|rcsb pdb:5PJB|rcsb pdb:5PJC|rcsb pdb:5PJD|rcsb pdb:5PJE|rcsb pdb:5PJF|rcsb pdb:5PJG|rcsb pdb:5PJ5|rcsb pdb:5PJH|rcsb pdb:5PJI|rcsb pdb:5PJJ|rcsb pdb:5PJK|rcsb pdb:5PJL|rcsb pdb:5PJM|rcsb pdb:5PJN|rcsb pdb:5PJO|rcsb pdb:5PJP|rcsb pdb:5PJQ|rcsb pdb:5PJR|rcsb pdb:5PJS|rcsb pdb:6ETT|rcsb pdb:6ETU|rcsb pdb:5PJT|rcsb pdb:6ETV|rcsb pdb:6ETW|rcsb pdb:6F5Q|rcsb pdb:6F5R|rcsb pdb:6F5S|rcsb pdb:6F5T|rcsb pdb:6H0W|rcsb pdb:6H0X|rcsb pdb:6H0Y|rcsb pdb:6H0Z|rcsb pdb:6H10|rcsb pdb:6H11|reactome:R-HSA-3214842|ensembl:ENSG00000186280(gene)|ensembl:ENST00000335080(transcript)|ensembl:ENST00000536741(transcript)|ensembl:ENST00000610872(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|rcsb pdb:5PJV|rcsb pdb:5PJW|rcsb pdb:5PJX|rcsb pdb:5PJY|rcsb pdb:5PJZ|rcsb pdb:5PK0|rcsb pdb:5PK1|rcsb pdb:5PK2|rcsb pdb:5PJU|rcsb pdb:5PK3|rcsb pdb:5PK4|rcsb pdb:5PK5|rcsb pdb:5PK6|rcsb pdb:5PK7|rcsb pdb:5PK8|rcsb pdb:5PK9|rcsb pdb:5PKA|rcsb pdb:5PKB|rcsb pdb:5PKC|rcsb pdb:5PKD|rcsb pdb:5PKE|rcsb pdb:5PKF|rcsb pdb:5PKG|rcsb pdb:5PKH|rcsb pdb:5PKI|rcsb pdb:5PKJ|rcsb pdb:5PKK|rcsb pdb:5PKL|rcsb pdb:5PKM|rcsb pdb:5PKN|rcsb pdb:5PKO|rcsb pdb:5PKP|rcsb pdb:5PKQ|rcsb pdb:5PKR|rcsb pdb:5PKS|rcsb pdb:5PKT|rcsb pdb:5PKU|rcsb pdb:5PKV|rcsb pdb:5PKW|rcsb pdb:5PKX|rcsb pdb:5PKY|rcsb pdb:5PKZ|rcsb pdb:5PL0|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072562"(blood microparticle)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|mint:Q6B0I6|rcsb pdb:3DXT|rcsb pdb:3DXU|rcsb pdb:4D6Q|rcsb pdb:4D6R|rcsb pdb:4D6S|rcsb pdb:4HON|rcsb pdb:5PL2|rcsb pdb:5PL3|rcsb pdb:5PL1|rcsb pdb:5PL4|rcsb pdb:5PL5|rcsb pdb:5PL6|rcsb pdb:5PL7|rcsb pdb:5PL8|rcsb pdb:5PL9|rcsb pdb:5PLA|rcsb pdb:5PLB|rcsb pdb:5PLC|rcsb pdb:5PLD|rcsb pdb:5PLE|rcsb pdb:5PLF|rcsb pdb:5PLG|rcsb pdb:5PLH|rcsb pdb:5PLI|rcsb pdb:5PLJ|rcsb pdb:5PLK|rcsb pdb:5PLL|rcsb pdb:5PLM|rcsb pdb:5PLN|rcsb pdb:5PLO|rcsb pdb:5PLP|rcsb pdb:5PLQ|rcsb pdb:5PLR|rcsb pdb:5PLS|rcsb pdb:5F5A|rcsb pdb:5F5C|rcsb pdb:5FP4|rcsb pdb:5FP7|rcsb pdb:5FP8|rcsb pdb:5FP9|rcsb pdb:5FPA|rcsb pdb:5FPB|rcsb pdb:5PH0|rcsb pdb:5PH1|rcsb pdb:5PH2|rcsb pdb:5PH3|rcsb pdb:5PH4|rcsb pdb:4HOO|rcsb pdb:5PH5|rcsb pdb:5PH6|rcsb pdb:5PH7|rcsb pdb:5PH8|rcsb pdb:5PH9|rcsb pdb:5PHA|rcsb pdb:5PHB|rcsb pdb:5PHC|rcsb pdb:5PHD|rcsb pdb:5PHE|rcsb pdb:5PLU|rcsb pdb:5PLV|rcsb pdb:5PLW|rcsb pdb:5PLX|rcsb pdb:5PLY|rcsb pdb:5PLZ|rcsb pdb:5PM0|rcsb pdb:5PM1|rcsb pdb:5PM2|rcsb pdb:5PM3|rcsb pdb:5PM4|rcsb pdb:5PM5|rcsb pdb:5PM6|rcsb pdb:5PM7|rcsb pdb:5PM8|rcsb pdb:5PM9|rcsb pdb:5PMA|rcsb pdb:5PMB|rcsb pdb:5PMC|rcsb pdb:5PMD|rcsb pdb:5PME|rcsb pdb:5PMF|rcsb pdb:5PMG|rcsb pdb:5PMH|rcsb pdb:5PMI|rcsb pdb:5PMJ|rcsb pdb:5PMK|rcsb pdb:5PML|rcsb pdb:5PMM|rcsb pdb:5PMN|rcsb pdb:5PMO|rcsb pdb:5PMP|rcsb pdb:5PMQ|rcsb pdb:5PMR|rcsb pdb:5PMS|rcsb pdb:5PMT|rcsb pdb:5PMU|rcsb pdb:5PMV|rcsb pdb:5PMW|rcsb pdb:5PMX|rcsb pdb:5PMY|rcsb pdb:5PMZ|rcsb pdb:5PN0|rcsb pdb:5PN1|rcsb pdb:5PN2|rcsb pdb:5PN3|rcsb pdb:5PN4|rcsb pdb:5PN5|rcsb pdb:5PN6|rcsb pdb:5PN7|rcsb pdb:5PN8|rcsb pdb:5PN9|rcsb pdb:5PNA|rcsb pdb:5PNB|rcsb pdb:5PNC|rcsb pdb:5PND|rcsb pdb:5PNE|rcsb pdb:5PNF|rcsb pdb:5PNG|rcsb pdb:5PNH|rcsb pdb:5PNI|rcsb pdb:5PNJ|rcsb pdb:5PNK|rcsb pdb:5PNL|rcsb pdb:5PNM|rcsb pdb:5PLT|rcsb pdb:5PNN|rcsb pdb:5PNO|rcsb pdb:5PNP|rcsb pdb:5PNQ|rcsb pdb:5PNR|rcsb pdb:5PNS|rcsb pdb:5PNU|rcsb pdb:5PNV|rcsb pdb:5PNW|rcsb pdb:6ETE|rcsb pdb:6ETG|rcsb pdb:6ETS|rcsb pdb:5PHJ|rcsb pdb:5PHK|rcsb pdb:5PHL|rcsb pdb:5PHM|rcsb pdb:5PHN|rcsb pdb:5PHO|rcsb pdb:5PHP|rcsb pdb:5PHQ|rcsb pdb:5PHR|rcsb pdb:5PHS|rcsb pdb:5PHT|rcsb pdb:5PHU|rcsb pdb:5PHV|rcsb pdb:5PHF|rcsb pdb:5PHG|rcsb pdb:5PHH|rcsb pdb:5PHI|rcsb pdb:5PHW|rcsb pdb:5PHX|rcsb pdb:5PHY|rcsb pdb:5PHZ|rcsb pdb:5PI0|rcsb pdb:5PI1|rcsb pdb:5PI2|rcsb pdb:5PI3|rcsb pdb:5PI4|dip:DIP-29606N refseq:NP_056110.2|ensembl:ENSG00000101596(gene)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR036277|interpro:IPR036890|interpro:IPR038892|mint:A6NHR9|rcsb pdb:6MW7|ensembl:ENST00000320876(transcript)|go:"GO:0001740"(Barr body)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006302"(double-strand break repair)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043584"(nose development)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0060820"(inactivation of X chromosome by heterochromatin assembly)|go:"GO:0060821"(obsolete inactivation of X chromosome by DNA methylation) - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:svQfKWBCSAPSGFAV5YPZXFvcqkk9606 rogid:7tHwsz7p8pAqG9grnerpgMTmt3Q9606 rigid:7fqj2Gju3X4HbV0gQNAzWx9cUhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6B0I6 uniprotkb:P62316 intact:EBI-4311651|uniprotkb:Q9NW76|uniprotkb:B3KPC4|uniprotkb:Q9NT41|uniprotkb:Q0VF39|ensembl:ENSP00000334181|ensembl:ENSP00000460897|ensembl:ENSP00000482224 intact:EBI-297993|uniprotkb:P43330|ensembl:ENSP00000342374|ensembl:ENSP00000465216|uniprotkb:A8K797|uniprotkb:J3KPM5 psi-mi:kdm4d_human(display_long)|uniprotkb:KDM4D(gene name)|psi-mi:KDM4D(display_short)|uniprotkb:JHDM3D(gene name synonym)|uniprotkb:JMJD2D(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3D(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2D(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4D"(gene name synonym) psi-mi:smd2_human(display_long)|uniprotkb:SNRPD2(gene name)|psi-mi:SNRPD2(display_short)|uniprotkb:snRNP core protein D2(gene name synonym)|uniprotkb:SNRPD1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480104|imex:IM-26985-481 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060509.2|rcsb pdb:5PI6|rcsb pdb:5PI7|rcsb pdb:5PI8|rcsb pdb:5PI9|rcsb pdb:5PIA|rcsb pdb:5PIB|rcsb pdb:5PIC|rcsb pdb:5PID|rcsb pdb:5PIE|rcsb pdb:5PIF|rcsb pdb:5PIG|rcsb pdb:5PIH|rcsb pdb:5PII|rcsb pdb:5PIJ|rcsb pdb:5PIK|rcsb pdb:5PIL|rcsb pdb:5PIM|rcsb pdb:5PIN|rcsb pdb:5PIO|rcsb pdb:5PIP|rcsb pdb:5PIQ|rcsb pdb:5PIR|rcsb pdb:5PIS|rcsb pdb:5PIT|rcsb pdb:5PIU|rcsb pdb:5PIV|rcsb pdb:5PIW|rcsb pdb:5PIX|rcsb pdb:5PIY|rcsb pdb:5PIZ|rcsb pdb:5PJ0|rcsb pdb:5PI5|rcsb pdb:5PJ1|rcsb pdb:5PJ2|rcsb pdb:5PJ3|rcsb pdb:5PJ4|rcsb pdb:5PJ6|rcsb pdb:5PJ7|rcsb pdb:5PJ8|rcsb pdb:5PJ9|rcsb pdb:5PJA|rcsb pdb:5PJB|rcsb pdb:5PJC|rcsb pdb:5PJD|rcsb pdb:5PJE|rcsb pdb:5PJF|rcsb pdb:5PJG|rcsb pdb:5PJ5|rcsb pdb:5PJH|rcsb pdb:5PJI|rcsb pdb:5PJJ|rcsb pdb:5PJK|rcsb pdb:5PJL|rcsb pdb:5PJM|rcsb pdb:5PJN|rcsb pdb:5PJO|rcsb pdb:5PJP|rcsb pdb:5PJQ|rcsb pdb:5PJR|rcsb pdb:5PJS|rcsb pdb:6ETT|rcsb pdb:6ETU|rcsb pdb:5PJT|rcsb pdb:6ETV|rcsb pdb:6ETW|rcsb pdb:6F5Q|rcsb pdb:6F5R|rcsb pdb:6F5S|rcsb pdb:6F5T|rcsb pdb:6H0W|rcsb pdb:6H0X|rcsb pdb:6H0Y|rcsb pdb:6H0Z|rcsb pdb:6H10|rcsb pdb:6H11|reactome:R-HSA-3214842|ensembl:ENSG00000186280(gene)|ensembl:ENST00000335080(transcript)|ensembl:ENST00000536741(transcript)|ensembl:ENST00000610872(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|rcsb pdb:5PJV|rcsb pdb:5PJW|rcsb pdb:5PJX|rcsb pdb:5PJY|rcsb pdb:5PJZ|rcsb pdb:5PK0|rcsb pdb:5PK1|rcsb pdb:5PK2|rcsb pdb:5PJU|rcsb pdb:5PK3|rcsb pdb:5PK4|rcsb pdb:5PK5|rcsb pdb:5PK6|rcsb pdb:5PK7|rcsb pdb:5PK8|rcsb pdb:5PK9|rcsb pdb:5PKA|rcsb pdb:5PKB|rcsb pdb:5PKC|rcsb pdb:5PKD|rcsb pdb:5PKE|rcsb pdb:5PKF|rcsb pdb:5PKG|rcsb pdb:5PKH|rcsb pdb:5PKI|rcsb pdb:5PKJ|rcsb pdb:5PKK|rcsb pdb:5PKL|rcsb pdb:5PKM|rcsb pdb:5PKN|rcsb pdb:5PKO|rcsb pdb:5PKP|rcsb pdb:5PKQ|rcsb pdb:5PKR|rcsb pdb:5PKS|rcsb pdb:5PKT|rcsb pdb:5PKU|rcsb pdb:5PKV|rcsb pdb:5PKW|rcsb pdb:5PKX|rcsb pdb:5PKY|rcsb pdb:5PKZ|rcsb pdb:5PL0|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072562"(blood microparticle)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|mint:Q6B0I6|rcsb pdb:3DXT|rcsb pdb:3DXU|rcsb pdb:4D6Q|rcsb pdb:4D6R|rcsb pdb:4D6S|rcsb pdb:4HON|rcsb pdb:5PL2|rcsb pdb:5PL3|rcsb pdb:5PL1|rcsb pdb:5PL4|rcsb pdb:5PL5|rcsb pdb:5PL6|rcsb pdb:5PL7|rcsb pdb:5PL8|rcsb pdb:5PL9|rcsb pdb:5PLA|rcsb pdb:5PLB|rcsb pdb:5PLC|rcsb pdb:5PLD|rcsb pdb:5PLE|rcsb pdb:5PLF|rcsb pdb:5PLG|rcsb pdb:5PLH|rcsb pdb:5PLI|rcsb pdb:5PLJ|rcsb pdb:5PLK|rcsb pdb:5PLL|rcsb pdb:5PLM|rcsb pdb:5PLN|rcsb pdb:5PLO|rcsb pdb:5PLP|rcsb pdb:5PLQ|rcsb pdb:5PLR|rcsb pdb:5PLS|rcsb pdb:5F5A|rcsb pdb:5F5C|rcsb pdb:5FP4|rcsb pdb:5FP7|rcsb pdb:5FP8|rcsb pdb:5FP9|rcsb pdb:5FPA|rcsb pdb:5FPB|rcsb pdb:5PH0|rcsb pdb:5PH1|rcsb pdb:5PH2|rcsb pdb:5PH3|rcsb pdb:5PH4|rcsb pdb:4HOO|rcsb pdb:5PH5|rcsb pdb:5PH6|rcsb pdb:5PH7|rcsb pdb:5PH8|rcsb pdb:5PH9|rcsb pdb:5PHA|rcsb pdb:5PHB|rcsb pdb:5PHC|rcsb pdb:5PHD|rcsb pdb:5PHE|rcsb pdb:5PLU|rcsb pdb:5PLV|rcsb pdb:5PLW|rcsb pdb:5PLX|rcsb pdb:5PLY|rcsb pdb:5PLZ|rcsb pdb:5PM0|rcsb pdb:5PM1|rcsb pdb:5PM2|rcsb pdb:5PM3|rcsb pdb:5PM4|rcsb pdb:5PM5|rcsb pdb:5PM6|rcsb pdb:5PM7|rcsb pdb:5PM8|rcsb pdb:5PM9|rcsb pdb:5PMA|rcsb pdb:5PMB|rcsb pdb:5PMC|rcsb pdb:5PMD|rcsb pdb:5PME|rcsb pdb:5PMF|rcsb pdb:5PMG|rcsb pdb:5PMH|rcsb pdb:5PMI|rcsb pdb:5PMJ|rcsb pdb:5PMK|rcsb pdb:5PML|rcsb pdb:5PMM|rcsb pdb:5PMN|rcsb pdb:5PMO|rcsb pdb:5PMP|rcsb pdb:5PMQ|rcsb pdb:5PMR|rcsb pdb:5PMS|rcsb pdb:5PMT|rcsb pdb:5PMU|rcsb pdb:5PMV|rcsb pdb:5PMW|rcsb pdb:5PMX|rcsb pdb:5PMY|rcsb pdb:5PMZ|rcsb pdb:5PN0|rcsb pdb:5PN1|rcsb pdb:5PN2|rcsb pdb:5PN3|rcsb pdb:5PN4|rcsb pdb:5PN5|rcsb pdb:5PN6|rcsb pdb:5PN7|rcsb pdb:5PN8|rcsb pdb:5PN9|rcsb pdb:5PNA|rcsb pdb:5PNB|rcsb pdb:5PNC|rcsb pdb:5PND|rcsb pdb:5PNE|rcsb pdb:5PNF|rcsb pdb:5PNG|rcsb pdb:5PNH|rcsb pdb:5PNI|rcsb pdb:5PNJ|rcsb pdb:5PNK|rcsb pdb:5PNL|rcsb pdb:5PNM|rcsb pdb:5PLT|rcsb pdb:5PNN|rcsb pdb:5PNO|rcsb pdb:5PNP|rcsb pdb:5PNQ|rcsb pdb:5PNR|rcsb pdb:5PNS|rcsb pdb:5PNU|rcsb pdb:5PNV|rcsb pdb:5PNW|rcsb pdb:6ETE|rcsb pdb:6ETG|rcsb pdb:6ETS|rcsb pdb:5PHJ|rcsb pdb:5PHK|rcsb pdb:5PHL|rcsb pdb:5PHM|rcsb pdb:5PHN|rcsb pdb:5PHO|rcsb pdb:5PHP|rcsb pdb:5PHQ|rcsb pdb:5PHR|rcsb pdb:5PHS|rcsb pdb:5PHT|rcsb pdb:5PHU|rcsb pdb:5PHV|rcsb pdb:5PHF|rcsb pdb:5PHG|rcsb pdb:5PHH|rcsb pdb:5PHI|rcsb pdb:5PHW|rcsb pdb:5PHX|rcsb pdb:5PHY|rcsb pdb:5PHZ|rcsb pdb:5PI0|rcsb pdb:5PI1|rcsb pdb:5PI2|rcsb pdb:5PI3|rcsb pdb:5PI4|dip:DIP-29606N ensembl:ENSG00000125743(gene)|ensembl:ENST00000342669(transcript)|ensembl:ENST00000588301(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990446"(U1 snRNP binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027248|mint:P62316|rcsb pdb:1B34|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:NP_004588.1|refseq:NP_808210.2|dip:DIP-31219N - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:svQfKWBCSAPSGFAV5YPZXFvcqkk9606 rogid:4OshNPT6N4dOcWMVXrF5Fm8dcnI9606 rigid:7fqj2Gju3X4HbV0gQNAzWx9cUhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6B0I6 uniprotkb:Q9Y3B4 intact:EBI-4311651|uniprotkb:Q9NW76|uniprotkb:B3KPC4|uniprotkb:Q9NT41|uniprotkb:Q0VF39|ensembl:ENSP00000334181|ensembl:ENSP00000460897|ensembl:ENSP00000482224 intact:EBI-1046261|ensembl:ENSP00000233468|uniprotkb:Q53TM1 psi-mi:kdm4d_human(display_long)|uniprotkb:KDM4D(gene name)|psi-mi:KDM4D(display_short)|uniprotkb:JHDM3D(gene name synonym)|uniprotkb:JMJD2D(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 3D(gene name synonym)|uniprotkb:Jumonji domain-containing protein 2D(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(9) demethylase 4D"(gene name synonym) psi-mi:sf3b6_human(display_long)|uniprotkb:SF3B6(gene name)|psi-mi:SF3B6(display_short)|uniprotkb:Pre-mRNA branch site protein p14(gene name synonym)|uniprotkb:SAP14(gene name synonym)|uniprotkb:SF3B14(gene name synonym)|uniprotkb:SF3B14A(gene name synonym)|uniprotkb:SF3b 14 kDa subunit(gene name synonym)|uniprotkb:Spliceosome-associated protein, 14-kDa(gene name synonym)|uniprotkb:Splicing factor 3b, subunit 6, 14kDa(gene name synonym)|uniprotkb:CGI-110(orf name)|uniprotkb:HSPC175(orf name)|uniprotkb:HT006(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480104|imex:IM-26985-481 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060509.2|rcsb pdb:5PI6|rcsb pdb:5PI7|rcsb pdb:5PI8|rcsb pdb:5PI9|rcsb pdb:5PIA|rcsb pdb:5PIB|rcsb pdb:5PIC|rcsb pdb:5PID|rcsb pdb:5PIE|rcsb pdb:5PIF|rcsb pdb:5PIG|rcsb pdb:5PIH|rcsb pdb:5PII|rcsb pdb:5PIJ|rcsb pdb:5PIK|rcsb pdb:5PIL|rcsb pdb:5PIM|rcsb pdb:5PIN|rcsb pdb:5PIO|rcsb pdb:5PIP|rcsb pdb:5PIQ|rcsb pdb:5PIR|rcsb pdb:5PIS|rcsb pdb:5PIT|rcsb pdb:5PIU|rcsb pdb:5PIV|rcsb pdb:5PIW|rcsb pdb:5PIX|rcsb pdb:5PIY|rcsb pdb:5PIZ|rcsb pdb:5PJ0|rcsb pdb:5PI5|rcsb pdb:5PJ1|rcsb pdb:5PJ2|rcsb pdb:5PJ3|rcsb pdb:5PJ4|rcsb pdb:5PJ6|rcsb pdb:5PJ7|rcsb pdb:5PJ8|rcsb pdb:5PJ9|rcsb pdb:5PJA|rcsb pdb:5PJB|rcsb pdb:5PJC|rcsb pdb:5PJD|rcsb pdb:5PJE|rcsb pdb:5PJF|rcsb pdb:5PJG|rcsb pdb:5PJ5|rcsb pdb:5PJH|rcsb pdb:5PJI|rcsb pdb:5PJJ|rcsb pdb:5PJK|rcsb pdb:5PJL|rcsb pdb:5PJM|rcsb pdb:5PJN|rcsb pdb:5PJO|rcsb pdb:5PJP|rcsb pdb:5PJQ|rcsb pdb:5PJR|rcsb pdb:5PJS|rcsb pdb:6ETT|rcsb pdb:6ETU|rcsb pdb:5PJT|rcsb pdb:6ETV|rcsb pdb:6ETW|rcsb pdb:6F5Q|rcsb pdb:6F5R|rcsb pdb:6F5S|rcsb pdb:6F5T|rcsb pdb:6H0W|rcsb pdb:6H0X|rcsb pdb:6H0Y|rcsb pdb:6H0Z|rcsb pdb:6H10|rcsb pdb:6H11|reactome:R-HSA-3214842|ensembl:ENSG00000186280(gene)|ensembl:ENST00000335080(transcript)|ensembl:ENST00000536741(transcript)|ensembl:ENST00000610872(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|rcsb pdb:5PJV|rcsb pdb:5PJW|rcsb pdb:5PJX|rcsb pdb:5PJY|rcsb pdb:5PJZ|rcsb pdb:5PK0|rcsb pdb:5PK1|rcsb pdb:5PK2|rcsb pdb:5PJU|rcsb pdb:5PK3|rcsb pdb:5PK4|rcsb pdb:5PK5|rcsb pdb:5PK6|rcsb pdb:5PK7|rcsb pdb:5PK8|rcsb pdb:5PK9|rcsb pdb:5PKA|rcsb pdb:5PKB|rcsb pdb:5PKC|rcsb pdb:5PKD|rcsb pdb:5PKE|rcsb pdb:5PKF|rcsb pdb:5PKG|rcsb pdb:5PKH|rcsb pdb:5PKI|rcsb pdb:5PKJ|rcsb pdb:5PKK|rcsb pdb:5PKL|rcsb pdb:5PKM|rcsb pdb:5PKN|rcsb pdb:5PKO|rcsb pdb:5PKP|rcsb pdb:5PKQ|rcsb pdb:5PKR|rcsb pdb:5PKS|rcsb pdb:5PKT|rcsb pdb:5PKU|rcsb pdb:5PKV|rcsb pdb:5PKW|rcsb pdb:5PKX|rcsb pdb:5PKY|rcsb pdb:5PKZ|rcsb pdb:5PL0|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0072562"(blood microparticle)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR003349(Transcription factor jumonji, JmjN)|mint:Q6B0I6|rcsb pdb:3DXT|rcsb pdb:3DXU|rcsb pdb:4D6Q|rcsb pdb:4D6R|rcsb pdb:4D6S|rcsb pdb:4HON|rcsb pdb:5PL2|rcsb pdb:5PL3|rcsb pdb:5PL1|rcsb pdb:5PL4|rcsb pdb:5PL5|rcsb pdb:5PL6|rcsb pdb:5PL7|rcsb pdb:5PL8|rcsb pdb:5PL9|rcsb pdb:5PLA|rcsb pdb:5PLB|rcsb pdb:5PLC|rcsb pdb:5PLD|rcsb pdb:5PLE|rcsb pdb:5PLF|rcsb pdb:5PLG|rcsb pdb:5PLH|rcsb pdb:5PLI|rcsb pdb:5PLJ|rcsb pdb:5PLK|rcsb pdb:5PLL|rcsb pdb:5PLM|rcsb pdb:5PLN|rcsb pdb:5PLO|rcsb pdb:5PLP|rcsb pdb:5PLQ|rcsb pdb:5PLR|rcsb pdb:5PLS|rcsb pdb:5F5A|rcsb pdb:5F5C|rcsb pdb:5FP4|rcsb pdb:5FP7|rcsb pdb:5FP8|rcsb pdb:5FP9|rcsb pdb:5FPA|rcsb pdb:5FPB|rcsb pdb:5PH0|rcsb pdb:5PH1|rcsb pdb:5PH2|rcsb pdb:5PH3|rcsb pdb:5PH4|rcsb pdb:4HOO|rcsb pdb:5PH5|rcsb pdb:5PH6|rcsb pdb:5PH7|rcsb pdb:5PH8|rcsb pdb:5PH9|rcsb pdb:5PHA|rcsb pdb:5PHB|rcsb pdb:5PHC|rcsb pdb:5PHD|rcsb pdb:5PHE|rcsb pdb:5PLU|rcsb pdb:5PLV|rcsb pdb:5PLW|rcsb pdb:5PLX|rcsb pdb:5PLY|rcsb pdb:5PLZ|rcsb pdb:5PM0|rcsb pdb:5PM1|rcsb pdb:5PM2|rcsb pdb:5PM3|rcsb pdb:5PM4|rcsb pdb:5PM5|rcsb pdb:5PM6|rcsb pdb:5PM7|rcsb pdb:5PM8|rcsb pdb:5PM9|rcsb pdb:5PMA|rcsb pdb:5PMB|rcsb pdb:5PMC|rcsb pdb:5PMD|rcsb pdb:5PME|rcsb pdb:5PMF|rcsb pdb:5PMG|rcsb pdb:5PMH|rcsb pdb:5PMI|rcsb pdb:5PMJ|rcsb pdb:5PMK|rcsb pdb:5PML|rcsb pdb:5PMM|rcsb pdb:5PMN|rcsb pdb:5PMO|rcsb pdb:5PMP|rcsb pdb:5PMQ|rcsb pdb:5PMR|rcsb pdb:5PMS|rcsb pdb:5PMT|rcsb pdb:5PMU|rcsb pdb:5PMV|rcsb pdb:5PMW|rcsb pdb:5PMX|rcsb pdb:5PMY|rcsb pdb:5PMZ|rcsb pdb:5PN0|rcsb pdb:5PN1|rcsb pdb:5PN2|rcsb pdb:5PN3|rcsb pdb:5PN4|rcsb pdb:5PN5|rcsb pdb:5PN6|rcsb pdb:5PN7|rcsb pdb:5PN8|rcsb pdb:5PN9|rcsb pdb:5PNA|rcsb pdb:5PNB|rcsb pdb:5PNC|rcsb pdb:5PND|rcsb pdb:5PNE|rcsb pdb:5PNF|rcsb pdb:5PNG|rcsb pdb:5PNH|rcsb pdb:5PNI|rcsb pdb:5PNJ|rcsb pdb:5PNK|rcsb pdb:5PNL|rcsb pdb:5PNM|rcsb pdb:5PLT|rcsb pdb:5PNN|rcsb pdb:5PNO|rcsb pdb:5PNP|rcsb pdb:5PNQ|rcsb pdb:5PNR|rcsb pdb:5PNS|rcsb pdb:5PNU|rcsb pdb:5PNV|rcsb pdb:5PNW|rcsb pdb:6ETE|rcsb pdb:6ETG|rcsb pdb:6ETS|rcsb pdb:5PHJ|rcsb pdb:5PHK|rcsb pdb:5PHL|rcsb pdb:5PHM|rcsb pdb:5PHN|rcsb pdb:5PHO|rcsb pdb:5PHP|rcsb pdb:5PHQ|rcsb pdb:5PHR|rcsb pdb:5PHS|rcsb pdb:5PHT|rcsb pdb:5PHU|rcsb pdb:5PHV|rcsb pdb:5PHF|rcsb pdb:5PHG|rcsb pdb:5PHH|rcsb pdb:5PHI|rcsb pdb:5PHW|rcsb pdb:5PHX|rcsb pdb:5PHY|rcsb pdb:5PHZ|rcsb pdb:5PI0|rcsb pdb:5PI1|rcsb pdb:5PI2|rcsb pdb:5PI3|rcsb pdb:5PI4|dip:DIP-29606N ensembl:ENST00000233468(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001825"(blastocyst formation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|ensembl:ENSG00000115128(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034150|interpro:IPR035979|mint:Q9Y3B4|rcsb pdb:2F9D|rcsb pdb:2F9J|rcsb pdb:2FHO|rcsb pdb:3LQV|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:NP_057131.1|dip:DIP-44132N - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:svQfKWBCSAPSGFAV5YPZXFvcqkk9606 rogid:7mhaXkmVqjfJGPdX1UDM+kN4vNI9606 rigid:7fqj2Gju3X4HbV0gQNAzWx9cUhM false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:P83881 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-1054835|uniprotkb:P09896|uniprotkb:P10661|uniprotkb:Q5J9I6|uniprotkb:Q08ES5|ensembl:ENSP00000446503 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:rl36a_human(display_long)|uniprotkb:60S ribosomal protein L44(gene name synonym)|uniprotkb:Cell migration-inducing gene 6 protein(gene name synonym)|uniprotkb:RPL36A(gene name)|psi-mi:RPL36A(display_short)|uniprotkb:MIG6(orf name)|uniprotkb:RPL44(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 15 protein(gene name synonym)|uniprotkb:GIG15(orf name)|uniprotkb:Large ribosomal subunit protein eL42(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480362|imex:IM-26985-101 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding) refseq:NP_066357.2|ensembl:ENSG00000241343(gene)|ensembl:ENST00000553110(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR000552(Ribosomal protein L44e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|mint:P83881|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:OrRyOEVJZbSdttK93KL/DS5YxJ89606 rigid:lGYgR3ayv6ZTfZBN4LrBP20DLZk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:P63167 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-349105|uniprotkb:Q15701|ensembl:ENSP00000242577|ensembl:ENSP00000376296|ensembl:ENSP00000376297|ensembl:ENSP00000446614|ensembl:ENSP00000447907 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:dyl1_human(display_long)|uniprotkb:DYNLL1(gene name)|psi-mi:DYNLL1(display_short)|uniprotkb:DLC1(gene name synonym)|uniprotkb:DNCLC1(gene name synonym)|uniprotkb:HDLC1(gene name synonym)|uniprotkb:Dynein light chain LC8-type 1(gene name synonym)|uniprotkb:8 kDa dynein light chain(gene name synonym)|uniprotkb:Protein inhibitor of neuronal nitric oxide synthase(gene name synonym)|uniprotkb:DNCL1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480362|imex:IM-26985-101 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding) refseq:NP_001032583.1|refseq:NP_001032584.1|refseq:NP_003737.1|go:"GO:0072686"(mitotic spindle)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097542"(ciliary tip)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:P63167|rcsb pdb:1CMI|rcsb pdb:3ZKE|rcsb pdb:3ZKF|rcsb pdb:6GZJ|rcsb pdb:6GZL|rcsb pdb:6RLB|rcsb pdb:6SC2|rcsb pdb:7D35|reactome:R-HSA-111446|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|go:"GO:0000776"(kinetochore)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0060271"(cilium assembly)|go:"GO:0005829"(cytosol)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007286"(spermatid development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030286"(dynein complex)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|ensembl:ENSG00000088986(gene)|ensembl:ENST00000242577(transcript)|ensembl:ENST00000392508(transcript)|ensembl:ENST00000392509(transcript)|ensembl:ENST00000548342(transcript)|ensembl:ENST00000549989(transcript)|dip:DIP-33150N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:Bra4LfaqYPMyo6xX9RD6G7Rdv809606 rigid:lGYgR3ayv6ZTfZBN4LrBP20DLZk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:Q9H1A4 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-395918|uniprotkb:Q2M3H8|uniprotkb:Q9BSE6|uniprotkb:Q9H8D0|ensembl:ENSP00000339109 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:apc1_human(display_long)|uniprotkb:ANAPC1(gene name)|psi-mi:ANAPC1(display_short)|uniprotkb:TSG24(gene name synonym)|uniprotkb:Cyclosome subunit 1(gene name synonym)|uniprotkb:Testis-specific gene 24 protein(gene name synonym)|uniprotkb:Mitotic checkpoint regulator(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480362|imex:IM-26985-101 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding) refseq:NP_073153.1|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENSG00000153107(gene)|rcsb pdb:4UI9|rcsb pdb:5A31|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|ensembl:ENST00000341068(transcript)|go:"GO:0005654"(nucleoplasm)|rcsb pdb:5L9U|go:"GO:0005680"(anaphase-promoting complex)|rcsb pdb:5LCW|go:"GO:0005829"(cytosol)|go:"GO:0007091"(metaphase/anaphase transition of mitotic cell cycle)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0051301"(cell division)|rcsb pdb:5LGG|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070979"(protein K11-linked ubiquitination)|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|interpro:IPR011989(Armadillo-like helical)|interpro:IPR024990|interpro:IPR041221|mint:Q9H1A4|dip:DIP-32940N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:GCcoaN+24WplwiaqcHwHsjyWn789606 rigid:lGYgR3ayv6ZTfZBN4LrBP20DLZk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:O75190 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-1053164|uniprotkb:A4D232|uniprotkb:O95806|uniprotkb:A8KAG0|uniprotkb:B4DN73|uniprotkb:E9PCZ2|uniprotkb:Q53EN8|uniprotkb:Q59EF2|uniprotkb:Q6FIC8|uniprotkb:Q75MA2|uniprotkb:Q9UIK6|uniprotkb:A8K7D8|ensembl:ENSP00000262177 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:dnjb6_human(display_long)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:MSJ-1(gene name synonym)|uniprotkb:HHDJ1(gene name synonym)|uniprotkb:DNAJB6(gene name)|psi-mi:DNAJB6(display_short)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:MSJ1(gene name synonym)|uniprotkb:MRJ(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480362|imex:IM-26985-101 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding) refseq:NP_005485.1|refseq:NP_490647.1|ensembl:ENSG00000105993(gene)|ensembl:ENST00000262177(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060710"(chorio-allantoic fusion)|go:"GO:0060715"(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:"GO:0060717"(chorion development)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:O75190|rcsb pdb:6U3R|rcsb pdb:6U3S|rcsb pdb:7JSQ|reactome:R-HSA-3371453|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process) - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:6X99Uu2SBlHsGCv61ZbwSz4LRp89606 rigid:lGYgR3ayv6ZTfZBN4LrBP20DLZk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:P62841 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-372635|uniprotkb:Q3KRA1|uniprotkb:P11174|uniprotkb:A5D8V9|uniprotkb:Q9UDC2|ensembl:ENSP00000467466 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:rs15_human(display_long)|uniprotkb:RIG protein(gene name synonym)|uniprotkb:RPS15(gene name)|psi-mi:RPS15(display_short)|uniprotkb:RIG(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS19(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480362|imex:IM-26985-101 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding) refseq:NP_001009.1|mint:P62841|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|ensembl:ENSG00000115268(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|ensembl:ENST00000592588(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0045202"(synapse)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0097421"(liver regeneration)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|interpro:IPR002222(Ribosomal protein S19/S15)|interpro:IPR005713(Ribosomal protein S15, eukaryotic/archaeal)|interpro:IPR020934|go:"GO:0003735"(structural constituent of ribosome)|interpro:IPR023575|rcsb pdb:6ZVH|rcsb pdb:6ZMT|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|rcsb pdb:6ZMW|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:lJJOew1txuTwFlhKu4Z+AkPS5H09606 rigid:lGYgR3ayv6ZTfZBN4LrBP20DLZk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:P52294 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-358383|uniprotkb:Q9BQ56|uniprotkb:Q6IBQ9|intact:EBI-1058734|ensembl:ENSP00000343701|uniprotkb:D3DN93 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:ima5_human(display_long)|uniprotkb:KPNA1(gene name)|psi-mi:KPNA1(display_short)|uniprotkb:RCH2(gene name synonym)|uniprotkb:Karyopherin subunit alpha-1(gene name synonym)|uniprotkb:SRP1-beta(gene name synonym)|uniprotkb:RAG cohort protein 2(gene name synonym)|uniprotkb:Nucleoprotein interactor 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480362|imex:IM-26985-101 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding) refseq:NP_002255.3|ensembl:ENSG00000114030(gene)|ensembl:ENST00000344337(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014841"(skeletal muscle satellite cell proliferation)|go:"GO:0014901"(satellite cell activation involved in skeletal muscle regeneration)|go:"GO:0030425"(dendrite)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:P52294|rcsb pdb:2JDQ|rcsb pdb:3TJ3|rcsb pdb:4B18|rcsb pdb:6WX9|reactome:R-HSA-1169408|reactome:R-HSA-140342|reactome:R-HSA-162592|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-180910|reactome:R-HSA-909733|reactome:R-HSA-9636249|dip:DIP-29296N|refseq:XP_005247494.1 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:eha8sOMYqe0OC6eXBA4eJLLsKFs9606 rigid:lGYgR3ayv6ZTfZBN4LrBP20DLZk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:Q9UJX4 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-395994|uniprotkb:Q8N4H7|uniprotkb:Q9BQD4|uniprotkb:E9PFB2|ensembl:ENSP00000261819 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:apc5_human(display_long)|uniprotkb:ANAPC5(gene name)|psi-mi:ANAPC5(display_short)|uniprotkb:APC5(gene name synonym)|uniprotkb:Cyclosome subunit 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480362|imex:IM-26985-101 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding) refseq:NP_057321.2|refseq:NP_001131031.1|refseq:NP_001317418.1|dip:DIP-32945N|rcsb pdb:5G04|rcsb pdb:5G05|rcsb pdb:5KHR|rcsb pdb:5KHU|rcsb pdb:5L9T|rcsb pdb:5L9U|rcsb pdb:5LCW|rcsb pdb:6Q6G|rcsb pdb:6Q6H|rcsb pdb:6TLJ|rcsb pdb:6TM5|rcsb pdb:6TNT|reactome:R-HSA-141430|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-176407|reactome:R-HSA-176408|reactome:R-HSA-176409|reactome:R-HSA-176412|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2559582|reactome:R-HSA-69017|reactome:R-HSA-8853884|reactome:R-HSA-9687136|reactome:R-HSA-983168|ensembl:ENSG00000089053(gene)|ensembl:ENST00000261819(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005680"(anaphase-promoting complex)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031145"(anaphase-promoting complex-dependent catabolic process)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0051301"(cell division)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR026000|interpro:IPR037679|mint:Q9UJX4|rcsb pdb:4UI9|rcsb pdb:5A31 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:Bg/ZL1IEXYdO6XblNQvxjhVX9tI9606 rigid:lGYgR3ayv6ZTfZBN4LrBP20DLZk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:Q8WW22 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-2555157|uniprotkb:Q8N7P2|uniprotkb:Q6AW87|ensembl:ENSP00000339581|ensembl:ENSP00000378321|uniprotkb:E9PDM9|uniprotkb:Q8N5Z4 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:dnja4_human(display_long)|uniprotkb:DNAJA4(gene name)|psi-mi:DNAJA4(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480362|imex:IM-26985-101 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding) refseq:NP_001123654.1|refseq:NP_001123655.1|refseq:NP_061072.3|ensembl:ENSG00000140403(gene)|ensembl:ENST00000343789(transcript)|ensembl:ENST00000394852(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0009408"(response to heat)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0042026"(protein refolding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0090084"(negative regulation of inclusion body assembly)|interpro:IPR001305(Heat shock protein DnaJ, cysteine-rich region)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR008971(HSP40/DnaJ peptide-binding)|interpro:IPR012724(Chaperone DnaJ)|interpro:IPR018253|interpro:IPR036410|interpro:IPR036869|interpro:IPR044713|mint:Q8WW22|reactome:R-HSA-3371497|refseq:XP_006720664.1|refseq:XP_005254592.1 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:GIrkxgRGaQvFml49F9iHH07gqTo9606 rigid:lGYgR3ayv6ZTfZBN4LrBP20DLZk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:P58557 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-2114647|uniprotkb:D3DSN2|uniprotkb:B7WPA9|uniprotkb:B7WPF7|ensembl:ENSP00000329614|ensembl:ENSP00000380805|ensembl:ENSP00000380813 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:ybey_human(display_long)|uniprotkb:YBEY(gene name)|psi-mi:YBEY(display_short)|uniprotkb:C21orf57(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480362|imex:IM-26985-101 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding) refseq:NP_478061.1|refseq:NP_001300951.1|refseq:NP_001300952.1|refseq:NP_001300953.1|refseq:NP_001300954.1|refseq:NP_001300955.1|ensembl:ENSG00000182362(gene)|ensembl:ENST00000329319(transcript)|ensembl:ENST00000397691(transcript)|ensembl:ENST00000397701(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0006364"(rRNA processing)|go:"GO:0046872"(metal ion binding)|interpro:IPR002036(Protein of unknown function UPF0054)|interpro:IPR020549|interpro:IPR023091|mint:P58557 - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:VOjeUF0iThxy1T2ywZGHB8ILorc9606 rigid:lGYgR3ayv6ZTfZBN4LrBP20DLZk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:Q9BRX2 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-1043580|uniprotkb:Q9GZS6|uniprotkb:Q9Y306|ensembl:ENSP00000274311 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:pelo_human(display_long)|uniprotkb:PELO(gene name)|psi-mi:PELO(display_short)|uniprotkb:CGI-17(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480362|imex:IM-26985-101 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding) ensembl:ENSG00000152684(gene)|ensembl:ENST00000274311(transcript)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0007049"(cell cycle)|go:"GO:0007492"(endoderm development)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0032790"(ribosome disassembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|go:"GO:0060231"(mesenchymal to epithelial transition)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0070966"(nuclear-transcribed mRNA catabolic process, no-go decay)|go:"GO:0071025"(RNA surveillance)|interpro:IPR004405(Probable translation factor pelota)|interpro:IPR005140(eRF1 domain 1)|interpro:IPR005141(eRF1 domain 2)|interpro:IPR005142(eRF1 domain 3)|interpro:IPR029064|interpro:IPR038069|interpro:IPR042226|mint:Q9BRX2|rcsb pdb:1X52|rcsb pdb:5EO3|rcsb pdb:5LZW|rcsb pdb:5LZX|rcsb pdb:5LZY|rcsb pdb:5LZZ|refseq:NP_057030.3 - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:EZIi8JN2tu0u4oH06fOus3LKjoo9606 rigid:lGYgR3ayv6ZTfZBN4LrBP20DLZk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:P62273 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-1054121|uniprotkb:P30054|uniprotkb:A8MZ73|ensembl:ENSP00000245458|ensembl:ENSP00000495033 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:rs29_human(display_long)|uniprotkb:RPS29(gene name)|psi-mi:RPS29(display_short)|uniprotkb:Small ribosomal subunit protein uS14(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480362|imex:IM-26985-101 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding) refseq:NP_001023.1|refseq:NP_001025172.1|ensembl:ENSG00000213741(gene)|ensembl:ENST00000245458(transcript)|ensembl:ENST00000556230(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|interpro:IPR001209(Ribosomal protein S14)|interpro:IPR018271|interpro:IPR039744|interpro:IPR043140|mint:P62273|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:vMgvFs6gwidbpv837yH2u0sSIAU9606 rigid:lGYgR3ayv6ZTfZBN4LrBP20DLZk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:Q15072 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-11914212|ensembl:ENSP00000392095|ensembl:ENSP00000400391|uniprotkb:Q2TB94 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:ozf_human(display_long)|uniprotkb:ZNF146(gene name)|psi-mi:ZNF146(display_short)|uniprotkb:OZF(gene name synonym)|uniprotkb:Only zinc finger protein(gene name synonym)|uniprotkb:Zinc finger protein 146(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480362|imex:IM-26985-101 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding) ensembl:ENSG00000167635(gene)|ensembl:ENST00000443387(transcript)|ensembl:ENST00000456324(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008201"(heparin binding)|go:"GO:0008270"(zinc ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q15072|refseq:NP_001093108.1|refseq:NP_001093109.1|refseq:NP_009076.2|refseq:XP_005259271.1|refseq:XP_016882733.1|refseq:XP_016882734.1|refseq:XP_016882735.1|refseq:XP_016882736.1 - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:N83ODeBIXcmLguIQ9eBIknUDsCs9606 rigid:lGYgR3ayv6ZTfZBN4LrBP20DLZk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:O75663 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-1054735|uniprotkb:Q5HYB2|uniprotkb:Q8IZ86|uniprotkb:B2R8V3|ensembl:ENSP00000356807 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:tiprl_human(display_long)|uniprotkb:Putative MAPK-activating protein PM10(gene name synonym)|uniprotkb:TIPRL(gene name)|psi-mi:TIPRL(display_short)|uniprotkb:Type 2A-interacting protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480362|imex:IM-26985-101 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding) refseq:NP_001026970.1|refseq:NP_690866.1|ensembl:ENSG00000143155(gene)|ensembl:ENST00000367833(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0005829"(cytosol)|go:"GO:0031929"(TOR signaling)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|interpro:IPR007303(TIP41-like protein)|mint:O75663|rcsb pdb:5D9G - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:Z+oUe9UFwPgBwdol1xGBq1k3b049606 rigid:lGYgR3ayv6ZTfZBN4LrBP20DLZk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:Q15773 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-1051875|intact:EBI-9357094|ensembl:ENSP00000203630|ensembl:ENSP00000403941|ensembl:ENSP00000446317 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:mlf2_human(display_long)|uniprotkb:Myelodysplasia-myeloid leukemia factor 2(gene name synonym)|uniprotkb:MLF2(gene name)|psi-mi:MLF2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480362|imex:IM-26985-101 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding) refseq:NP_005430.1|ensembl:ENSG00000089693(gene)|ensembl:ENST00000203630(transcript)|ensembl:ENST00000435120(transcript)|ensembl:ENST00000539187(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016020"(membrane)|interpro:IPR019376|mint:Q15773 - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:Ix7bMALTVwBVty3IAuUn+PP/0BU9606 rigid:lGYgR3ayv6ZTfZBN4LrBP20DLZk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y468 uniprotkb:P17029 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 intact:EBI-10199654|uniprotkb:Q8TBW5|uniprotkb:Q2M1U1|uniprotkb:A4D294|uniprotkb:Q8TEK7|uniprotkb:P52745|ensembl:ENSP00000323148 psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:zksc1_human(display_long)|uniprotkb:ZKSCAN1(gene name)|psi-mi:ZKSCAN1(display_short)|uniprotkb:KOX18(gene name synonym)|uniprotkb:ZNF139(gene name synonym)|uniprotkb:ZNF36(gene name synonym)|uniprotkb:Zinc finger protein 139(gene name synonym)|uniprotkb:Zinc finger protein 36(gene name synonym)|uniprotkb:Zinc finger protein KOX18(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480362|imex:IM-26985-101 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding) refseq:NP_003430.1|refseq:XP_011514861.1|ensembl:ENSG00000106261(gene)|ensembl:ENST00000324306(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003309(Transcriptional regulator SCAN)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|interpro:IPR038269|mint:P17029|reactome:R-HSA-212436|refseq:NP_001333510.1 - - comment:"author score: 36" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rogid:ZqlH+CM//MCv5xd6qF68dvc2xcM9606 rigid:lGYgR3ayv6ZTfZBN4LrBP20DLZk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N371 uniprotkb:P05114 intact:EBI-750326|uniprotkb:B4DLU9|uniprotkb:Q6VAK5|uniprotkb:Q9H8B1|ensembl:ENSP00000286096 intact:EBI-3915525|uniprotkb:Q3KQR8|ensembl:ENSP00000370125 psi-mi:kdm8_human(display_long)|uniprotkb:KDM8(gene name)|psi-mi:KDM8(display_short)|uniprotkb:JMJD5(gene name synonym)|uniprotkb:JmjC domain-containing protein 5(gene name synonym)|uniprotkb:Jumonji C domain-containing protein 5(gene name synonym)|uniprotkb:"L-arginine (3R)-hydroxylase KDM8"(gene name synonym) psi-mi:hmgn1_human(display_long)|uniprotkb:HMGN1(gene name)|psi-mi:HMGN1(display_short)|uniprotkb:HMG14(gene name synonym)|uniprotkb:High mobility group nucleosome-binding domain-containing protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480323|imex:IM-26985-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138820.1|refseq:NP_079049.2|ensembl:ENSG00000155666(gene)|ensembl:ENST00000286096(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003682"(chromatin binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0031648"(protein destabilization)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:0140554"|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR041667|mint:Q8N371|rcsb pdb:3UYJ|rcsb pdb:4AAP|rcsb pdb:6F4T|rcsb pdb:6I9L|rcsb pdb:6I9M|rcsb pdb:6I9N|rcsb pdb:4GAZ|rcsb pdb:4GJY|rcsb pdb:4GJZ|rcsb pdb:4QU1|rcsb pdb:5FBJ|rcsb pdb:6AVS|rcsb pdb:6AX3|rcsb pdb:6F4M|rcsb pdb:6F4N|rcsb pdb:6F4O|rcsb pdb:6F4P|rcsb pdb:6F4Q|rcsb pdb:6F4R|rcsb pdb:6F4S refseq:NP_004956.5|ensembl:ENSG00000205581(gene)|ensembl:ENST00000380749(transcript)|go:"GO:0000720"(pyrimidine dimer repair by nucleotide-excision repair)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010224"(response to UV-B)|go:"GO:0010225"(response to UV-C)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0048597"(post-embryonic camera-type eye morphogenesis)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:1901666"(positive regulation of NAD+ ADP-ribosyltransferase activity)|interpro:IPR000079(High mobility group protein HMG14 and HMG17)|mint:P05114|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xMY4ykJyXdyFo1lNfe6RekrAAhE9606 rogid:2Ns7EUwCgpj8Gj6uTuB1K6UZksc9606 rigid:eupzxLP4recmXfFtMzMZn/eVxOY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N371 uniprotkb:P05204 intact:EBI-750326|uniprotkb:B4DLU9|uniprotkb:Q6VAK5|uniprotkb:Q9H8B1|ensembl:ENSP00000286096 intact:EBI-1758689|uniprotkb:Q0VGD5|uniprotkb:Q6FGI5|uniprotkb:Q96C64|ensembl:ENSP00000355228|ensembl:ENSP00000481160 psi-mi:kdm8_human(display_long)|uniprotkb:KDM8(gene name)|psi-mi:KDM8(display_short)|uniprotkb:JMJD5(gene name synonym)|uniprotkb:JmjC domain-containing protein 5(gene name synonym)|uniprotkb:Jumonji C domain-containing protein 5(gene name synonym)|uniprotkb:"L-arginine (3R)-hydroxylase KDM8"(gene name synonym) psi-mi:hmgn2_human(display_long)|uniprotkb:HMGN2(gene name)|psi-mi:HMGN2(display_short)|uniprotkb:HMG17(gene name synonym)|uniprotkb:High mobility group nucleosome-binding domain-containing protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480323|imex:IM-26985-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138820.1|refseq:NP_079049.2|ensembl:ENSG00000155666(gene)|ensembl:ENST00000286096(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003682"(chromatin binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0031648"(protein destabilization)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:0140554"|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR041667|mint:Q8N371|rcsb pdb:3UYJ|rcsb pdb:4AAP|rcsb pdb:6F4T|rcsb pdb:6I9L|rcsb pdb:6I9M|rcsb pdb:6I9N|rcsb pdb:4GAZ|rcsb pdb:4GJY|rcsb pdb:4GJZ|rcsb pdb:4QU1|rcsb pdb:5FBJ|rcsb pdb:6AVS|rcsb pdb:6AX3|rcsb pdb:6F4M|rcsb pdb:6F4N|rcsb pdb:6F4O|rcsb pdb:6F4P|rcsb pdb:6F4Q|rcsb pdb:6F4R|rcsb pdb:6F4S refseq:NP_005508.1|ensembl:ENSG00000198830(gene)|ensembl:ENST00000361427(transcript)|ensembl:ENST00000619352(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000079(High mobility group protein HMG14 and HMG17)|mint:P05204 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xMY4ykJyXdyFo1lNfe6RekrAAhE9606 rogid:j8Khsp7BUJh0L9SicpVNR8LP6ZU9606 rigid:eupzxLP4recmXfFtMzMZn/eVxOY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N371 uniprotkb:Q8N9N8 intact:EBI-750326|uniprotkb:B4DLU9|uniprotkb:Q6VAK5|uniprotkb:Q9H8B1|ensembl:ENSP00000286096 intact:EBI-750700|uniprotkb:Q9BSC1|uniprotkb:B2R4N5|ensembl:ENSP00000309175|ensembl:ENSP00000434056|ensembl:ENSP00000435439|ensembl:ENSP00000435942|ensembl:ENSP00000436644 psi-mi:kdm8_human(display_long)|uniprotkb:KDM8(gene name)|psi-mi:KDM8(display_short)|uniprotkb:JMJD5(gene name synonym)|uniprotkb:JmjC domain-containing protein 5(gene name synonym)|uniprotkb:Jumonji C domain-containing protein 5(gene name synonym)|uniprotkb:"L-arginine (3R)-hydroxylase KDM8"(gene name synonym) psi-mi:eif1a_human(display_long)|uniprotkb:EIF1AD(gene name)|psi-mi:EIF1AD(display_short)|uniprotkb:Eukaryotic translation initiation factor 1A domain-containing protein(gene name synonym)|uniprotkb:Haponin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480323|imex:IM-26985-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138820.1|refseq:NP_079049.2|ensembl:ENSG00000155666(gene)|ensembl:ENST00000286096(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003682"(chromatin binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0031648"(protein destabilization)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:0140554"|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR041667|mint:Q8N371|rcsb pdb:3UYJ|rcsb pdb:4AAP|rcsb pdb:6F4T|rcsb pdb:6I9L|rcsb pdb:6I9M|rcsb pdb:6I9N|rcsb pdb:4GAZ|rcsb pdb:4GJY|rcsb pdb:4GJZ|rcsb pdb:4QU1|rcsb pdb:5FBJ|rcsb pdb:6AVS|rcsb pdb:6AX3|rcsb pdb:6F4M|rcsb pdb:6F4N|rcsb pdb:6F4O|rcsb pdb:6F4P|rcsb pdb:6F4Q|rcsb pdb:6F4R|rcsb pdb:6F4S refseq:NP_001229410.1|refseq:NP_001229411.1|refseq:NP_001229412.1|refseq:NP_001229413.1|refseq:NP_001229414.1|refseq:NP_001229415.1|refseq:NP_115701.2|refseq:XP_016873901.1|ensembl:ENSG00000175376(gene)|ensembl:ENST00000312234(transcript)|ensembl:ENST00000526451(transcript)|ensembl:ENST00000527249(transcript)|ensembl:ENST00000529964(transcript)|ensembl:ENST00000533544(transcript)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045111"(intermediate filament cytoskeleton)|interpro:IPR001253("Eukaryotic initiation factor 1A (eIF-1A)")|interpro:IPR006196(S1, IF1 type)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR039294|mint:Q8N9N8|rcsb pdb:2DGY|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xMY4ykJyXdyFo1lNfe6RekrAAhE9606 rogid:wzCkR1JRRdV7hxpmMBqthJKxJPY9606 rigid:eupzxLP4recmXfFtMzMZn/eVxOY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N371 uniprotkb:P58876 intact:EBI-750326|uniprotkb:B4DLU9|uniprotkb:Q6VAK5|uniprotkb:Q9H8B1|ensembl:ENSP00000286096 intact:EBI-4409942|ensembl:ENSP00000289316|ensembl:ENSP00000367008 psi-mi:kdm8_human(display_long)|uniprotkb:KDM8(gene name)|psi-mi:KDM8(display_short)|uniprotkb:JMJD5(gene name synonym)|uniprotkb:JmjC domain-containing protein 5(gene name synonym)|uniprotkb:Jumonji C domain-containing protein 5(gene name synonym)|uniprotkb:"L-arginine (3R)-hydroxylase KDM8"(gene name synonym) psi-mi:h2b1d_human(display_long)|uniprotkb:Histone H2B.b(gene name synonym)|uniprotkb:H2BC5(gene name)|psi-mi:H2BC5(display_short)|uniprotkb:H2B-clustered histone 5(gene name synonym)|uniprotkb:H2BFB(gene name synonym)|uniprotkb:HIRA-interacting protein 2(gene name synonym)|uniprotkb:HIRIP2(gene name synonym)|uniprotkb:HIST1H2BD(gene name synonym)|uniprotkb:Histone H2B.1 B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480323|imex:IM-26985-27 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138820.1|refseq:NP_079049.2|ensembl:ENSG00000155666(gene)|ensembl:ENST00000286096(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003682"(chromatin binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0031648"(protein destabilization)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:0140554"|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR041667|mint:Q8N371|rcsb pdb:3UYJ|rcsb pdb:4AAP|rcsb pdb:6F4T|rcsb pdb:6I9L|rcsb pdb:6I9M|rcsb pdb:6I9N|rcsb pdb:4GAZ|rcsb pdb:4GJY|rcsb pdb:4GJZ|rcsb pdb:4QU1|rcsb pdb:5FBJ|rcsb pdb:6AVS|rcsb pdb:6AX3|rcsb pdb:6F4M|rcsb pdb:6F4N|rcsb pdb:6F4O|rcsb pdb:6F4P|rcsb pdb:6F4Q|rcsb pdb:6F4R|rcsb pdb:6F4S refseq:NP_066407.1|refseq:NP_619790.1|ensembl:ENSG00000158373(gene)|ensembl:ENST00000289316(transcript)|ensembl:ENST00000377777(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P58876|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|go:"GO:0005634"(nucleus) - - comment:"author score: 30" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xMY4ykJyXdyFo1lNfe6RekrAAhE9606 rogid:07VBw5MCphdkMydMOPSjVqpGriI9606 rigid:eupzxLP4recmXfFtMzMZn/eVxOY false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13601 uniprotkb:Q01469 intact:EBI-744525|intact:EBI-28971604|ensembl:ENSP00000229214|uniprotkb:Q8NEA8|uniprotkb:Q8TC37|uniprotkb:Q96AT5|uniprotkb:A0FIK6|uniprotkb:A0JLP0|uniprotkb:B2R989|uniprotkb:E7EUQ0 intact:EBI-1054073|uniprotkb:B2R4K0|ensembl:ENSP00000297258 psi-mi:krr1_human(display_long)|uniprotkb:HIV-1 Rev-binding protein 2(gene name synonym)|uniprotkb:Rev-interacting protein 1(gene name synonym)|uniprotkb:KRR1(gene name)|psi-mi:KRR1(display_short)|uniprotkb:HRB2(gene name synonym)|uniprotkb:KRR-R motif-containing protein 1(gene name synonym) psi-mi:fabp5_human(display_long)|uniprotkb:Epidermal-type fatty acid-binding protein(gene name synonym)|uniprotkb:Psoriasis-associated fatty acid-binding protein homolog(gene name synonym)|uniprotkb:FABP5(gene name)|psi-mi:FABP5(display_short)|uniprotkb:Fatty acid-binding protein, epidermal(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480341|imex:IM-26985-483 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000229214|ensembl:ENST00000438169|ensembl:ENSP00000411740|ensembl:ENSG00000111615(gene)|ensembl:ENST00000229214(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0032040"(small-subunit processome)|go:"GO:0045171"(intercellular bridge)|interpro:IPR004087(K Homology)|interpro:IPR024166|interpro:IPR036612|interpro:IPR041174|mint:Q13601|refseq:NP_008974.5|reactome:R-HSA-6790901|reactome:R-HSA-6791226 refseq:NP_001435.1|ensembl:ENSG00000164687(gene)|ensembl:ENST00000297258(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0008289"(lipid binding)|go:"GO:0008544"(epidermis development)|go:"GO:0010829"(negative regulation of glucose transmembrane transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031392"(regulation of prostaglandin biosynthetic process)|go:"GO:0035360"(positive regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099178"(regulation of retrograde trans-synaptic signaling by endocanabinoid)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990379"(lipid transport across blood-brain barrier)|interpro:IPR000463(Cytosolic fatty-acid binding)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR012674(Calycin)|interpro:IPR031259|mint:Q01469|rcsb pdb:1B56|rcsb pdb:1JJJ|rcsb pdb:4AZM|rcsb pdb:4AZR|rcsb pdb:4LKP|rcsb pdb:4LKT|rcsb pdb:5HZ5|rcsb pdb:5UR9|reactome:R-HSA-163560|reactome:R-HSA-5362517|reactome:R-HSA-6798695 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:uBKNL/aw4wEssKJulbqQVWcH7ZI9606 rogid:vxp81/mezHcm5oo27QOmAM8Y5dI9606 rigid:Q7ZA0aNFQIC3+30qvtHcmWT5ZAE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13601 uniprotkb:P62277 intact:EBI-744525|intact:EBI-28971604|ensembl:ENSP00000229214|uniprotkb:Q8NEA8|uniprotkb:Q8TC37|uniprotkb:Q96AT5|uniprotkb:A0FIK6|uniprotkb:A0JLP0|uniprotkb:B2R989|uniprotkb:E7EUQ0 intact:EBI-351850|uniprotkb:P19116|uniprotkb:Q02546|uniprotkb:Q29200|uniprotkb:Q498Y0|uniprotkb:B2R549|ensembl:ENSP00000435777 psi-mi:krr1_human(display_long)|uniprotkb:HIV-1 Rev-binding protein 2(gene name synonym)|uniprotkb:Rev-interacting protein 1(gene name synonym)|uniprotkb:KRR1(gene name)|psi-mi:KRR1(display_short)|uniprotkb:HRB2(gene name synonym)|uniprotkb:KRR-R motif-containing protein 1(gene name synonym) psi-mi:rs13_human(display_long)|uniprotkb:RPS13(gene name)|psi-mi:RPS13(display_short)|uniprotkb:Small ribosomal subunit protein uS15(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480341|imex:IM-26985-483 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000229214|ensembl:ENST00000438169|ensembl:ENSP00000411740|ensembl:ENSG00000111615(gene)|ensembl:ENST00000229214(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0032040"(small-subunit processome)|go:"GO:0045171"(intercellular bridge)|interpro:IPR004087(K Homology)|interpro:IPR024166|interpro:IPR036612|interpro:IPR041174|mint:Q13601|refseq:NP_008974.5|reactome:R-HSA-6790901|reactome:R-HSA-6791226 refseq:NP_001008.1|ensembl:ENSG00000110700(gene)|ensembl:ENST00000525634(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR000589(Ribosomal protein S15)|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR012606(Ribosomal protein S13/S15, N-terminal)|interpro:IPR023029|mint:P62277|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6OM7|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:uBKNL/aw4wEssKJulbqQVWcH7ZI9606 rogid:GmlWYkXKxX6YwpEtzNABb+ZcytI9606 rigid:Q7ZA0aNFQIC3+30qvtHcmWT5ZAE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13601 uniprotkb:P47929 intact:EBI-744525|intact:EBI-28971604|ensembl:ENSP00000229214|uniprotkb:Q8NEA8|uniprotkb:Q8TC37|uniprotkb:Q96AT5|uniprotkb:A0FIK6|uniprotkb:A0JLP0|uniprotkb:B2R989|uniprotkb:E7EUQ0 intact:EBI-357504|ensembl:ENSP00000313571|ensembl:ENSP00000367891|ensembl:ENSP00000489395|ensembl:ENSP00000489582|uniprotkb:Q6IB87 psi-mi:krr1_human(display_long)|uniprotkb:HIV-1 Rev-binding protein 2(gene name synonym)|uniprotkb:Rev-interacting protein 1(gene name synonym)|uniprotkb:KRR1(gene name)|psi-mi:KRR1(display_short)|uniprotkb:HRB2(gene name synonym)|uniprotkb:KRR-R motif-containing protein 1(gene name synonym) psi-mi:leg7_human(display_long)|uniprotkb:LGALS7(gene name)|psi-mi:LGALS7(display_short)|uniprotkb:PIG1(gene name synonym)|uniprotkb:HKL-14(gene name synonym)|uniprotkb:PI7(gene name synonym)|uniprotkb:p53-induced gene 1 protein(gene name synonym)|uniprotkb:LGALS7B(gene name)|psi-mi:LGALS7B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480341|imex:IM-26985-483 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000229214|ensembl:ENST00000438169|ensembl:ENSP00000411740|ensembl:ENSG00000111615(gene)|ensembl:ENST00000229214(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0032040"(small-subunit processome)|go:"GO:0045171"(intercellular bridge)|interpro:IPR004087(K Homology)|interpro:IPR024166|interpro:IPR036612|interpro:IPR041174|mint:Q13601|refseq:NP_008974.5|reactome:R-HSA-6790901|reactome:R-HSA-6791226 ensembl:ENSG00000178934(gene)|ensembl:ENSG00000205076(gene)|ensembl:ENSG00000282902(gene)|ensembl:ENSG00000283082(gene)|ensembl:ENST00000314980(transcript)|ensembl:ENST00000378626(transcript)|ensembl:ENST00000634448(transcript)|ensembl:ENST00000634800(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016936"(galactoside binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000562"(negative regulation of CD4-positive, alpha-beta T cell proliferation)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR030640|interpro:IPR044156|mint:P47929|rcsb pdb:1BKZ|rcsb pdb:2GAL|rcsb pdb:3GAL|rcsb pdb:3ZXE|rcsb pdb:3ZXF|rcsb pdb:4GAL|rcsb pdb:4UW3|rcsb pdb:4UW4|rcsb pdb:4UW5|rcsb pdb:4UW6|rcsb pdb:4XBQ|rcsb pdb:4Y26|rcsb pdb:5GAL|rcsb pdb:5H9Q|rcsb pdb:5H9S|refseq:NP_001035972.1|refseq:NP_002298.1 - - comment:"author score: 33" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:uBKNL/aw4wEssKJulbqQVWcH7ZI9606 rogid:TIAlvVZ7rOYqTAGrYAFbJY231gc9606 rigid:Q7ZA0aNFQIC3+30qvtHcmWT5ZAE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13601 uniprotkb:Q96EW2 intact:EBI-744525|intact:EBI-28971604|ensembl:ENSP00000229214|uniprotkb:Q8NEA8|uniprotkb:Q8TC37|uniprotkb:Q96AT5|uniprotkb:A0FIK6|uniprotkb:A0JLP0|uniprotkb:B2R989|uniprotkb:E7EUQ0 intact:EBI-720457|uniprotkb:Q6P476|uniprotkb:Q8N8J4|uniprotkb:Q8NHH6|uniprotkb:Q8WWF0|ensembl:ENSP00000302562 psi-mi:krr1_human(display_long)|uniprotkb:HIV-1 Rev-binding protein 2(gene name synonym)|uniprotkb:Rev-interacting protein 1(gene name synonym)|uniprotkb:KRR1(gene name)|psi-mi:KRR1(display_short)|uniprotkb:HRB2(gene name synonym)|uniprotkb:KRR-R motif-containing protein 1(gene name synonym) psi-mi:hbap1_human(display_long)|uniprotkb:27 kDa heat shock protein-associated protein 1(gene name synonym)|uniprotkb:Protein associated with small stress protein 1(gene name synonym)|uniprotkb:HSPBAP1(gene name)|psi-mi:HSPBAP1(display_short)|uniprotkb:PASS1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480341|imex:IM-26985-483 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000229214|ensembl:ENST00000438169|ensembl:ENSP00000411740|ensembl:ENSG00000111615(gene)|ensembl:ENST00000229214(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0032040"(small-subunit processome)|go:"GO:0045171"(intercellular bridge)|interpro:IPR004087(K Homology)|interpro:IPR024166|interpro:IPR036612|interpro:IPR041174|mint:Q13601|refseq:NP_008974.5|reactome:R-HSA-6790901|reactome:R-HSA-6791226 refseq:NP_078886.2|ensembl:ENSG00000169087(gene)|ensembl:ENST00000306103(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR013296("Protein Associated with Small Stress protein 1 (PASS1)")|interpro:IPR041667|mint:Q96EW2|refseq:NP_001307657.1|refseq:XP_005247819.1 - - comment:"author score: 39" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:uBKNL/aw4wEssKJulbqQVWcH7ZI9606 rogid:5KvIFh1GwZSyAKD2EloRz2oweNk9606 rigid:Q7ZA0aNFQIC3+30qvtHcmWT5ZAE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13601 uniprotkb:Q8N9T8 intact:EBI-744525|intact:EBI-28971604|ensembl:ENSP00000229214|uniprotkb:Q8NEA8|uniprotkb:Q8TC37|uniprotkb:Q96AT5|uniprotkb:A0FIK6|uniprotkb:A0JLP0|uniprotkb:B2R989|uniprotkb:E7EUQ0 intact:EBI-724923|uniprotkb:Q2M1R5|uniprotkb:Q2M1R7|uniprotkb:Q7L5J7|uniprotkb:Q96G92|uniprotkb:Q9BU50|uniprotkb:Q9H6I1|uniprotkb:Q9H978|ensembl:ENSP00000320917 psi-mi:krr1_human(display_long)|uniprotkb:HIV-1 Rev-binding protein 2(gene name synonym)|uniprotkb:Rev-interacting protein 1(gene name synonym)|uniprotkb:KRR1(gene name)|psi-mi:KRR1(display_short)|uniprotkb:HRB2(gene name synonym)|uniprotkb:KRR-R motif-containing protein 1(gene name synonym) psi-mi:kri1_human(display_long)|uniprotkb:KRI1(gene name)|psi-mi:KRI1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480341|imex:IM-26985-483 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000229214|ensembl:ENST00000438169|ensembl:ENSP00000411740|ensembl:ENSG00000111615(gene)|ensembl:ENST00000229214(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0032040"(small-subunit processome)|go:"GO:0045171"(intercellular bridge)|interpro:IPR004087(K Homology)|interpro:IPR024166|interpro:IPR036612|interpro:IPR041174|mint:Q13601|refseq:NP_008974.5|reactome:R-HSA-6790901|reactome:R-HSA-6791226 refseq:NP_075384.3|ensembl:ENSG00000129347(gene)|ensembl:ENST00000312962(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0030686"(90S preribosome)|interpro:IPR018034|interpro:IPR024626|mint:Q8N9T8 - - comment:"author score: 97" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:uBKNL/aw4wEssKJulbqQVWcH7ZI9606 rogid:sIRmrP/c3tSmEAj1usRGN3R3Bh09606 rigid:Q7ZA0aNFQIC3+30qvtHcmWT5ZAE false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969R5 uniprotkb:Q9UBB4 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 intact:EBI-702390|uniprotkb:O14998|uniprotkb:O15009|uniprotkb:Q6I9X4|uniprotkb:A6NLC4|uniprotkb:B4DG05|ensembl:ENSP00000252934 psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:atx10_human(display_long)|uniprotkb:Spinocerebellar ataxia type 10 protein(gene name synonym)|uniprotkb:Brain protein E46 homolog(gene name synonym)|uniprotkb:ATXN10(gene name)|psi-mi:ATXN10(display_short)|uniprotkb:SCA10(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480413|imex:IM-26985-103 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750 refseq:NP_001161093.1|refseq:NP_037368.1|ensembl:ENSG00000130638(gene)|ensembl:ENST00000252934(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007399"(nervous system development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030425"(dendrite)|go:"GO:0031175"(neuron projection development)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060271"(cilium assembly)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019156|mint:Q9UBB4 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rogid:kQ+1aM5ZEzIlpH2lKWFGVSrCDww9606 rigid:VP+vsXKNjGNsAvmRbmlfyFjcswo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969R5 uniprotkb:P04004 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 intact:EBI-1036653|uniprotkb:P01141|uniprotkb:Q9BSH7|uniprotkb:B2R7G0|ensembl:ENSP00000226218 psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:vtnc_human(display_long)|uniprotkb:VTN(gene name)|psi-mi:VTN(display_short)|uniprotkb:Serum-spreading factor(gene name synonym)|uniprotkb:V75(gene name synonym)|uniprotkb:S-protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480413|imex:IM-26985-103 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750 refseq:NP_000629.3|ensembl:ENSG00000109072(gene)|ensembl:ENST00000226218(transcript)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008201"(heparin binding)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016477"(cell migration)|go:"GO:0030195"(negative regulation of blood coagulation)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030949"(positive regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0061302"(smooth muscle cell-matrix adhesion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071062"(alphav-beta3 integrin-vitronectin complex)|go:"GO:0072562"(blood microparticle)|go:"GO:0090303"(positive regulation of wound healing)|interpro:IPR000585(Hemopexin)|interpro:IPR001212(Somatomedin B)|interpro:IPR018486|interpro:IPR018487|interpro:IPR020436|interpro:IPR036024|interpro:IPR036375|mint:P04004|rcsb pdb:1OC0|rcsb pdb:1S4G|rcsb pdb:1SSU|rcsb pdb:2JQ8|rcsb pdb:3BT1|rcsb pdb:3BT2|rcsb pdb:4K24|rcsb pdb:6O5E|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-977606|dip:DIP-36566N - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rogid:07qxfQS6kbUZGwPyNj8/LTetT6I9606 rigid:VP+vsXKNjGNsAvmRbmlfyFjcswo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969R5 uniprotkb:P53396 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 intact:EBI-1042794|uniprotkb:Q13037|uniprotkb:Q9BRL0|uniprotkb:B4E3P0|uniprotkb:B4DIM0|ensembl:ENSP00000253792|ensembl:ENSP00000466259 psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:acly_human(display_long)|uniprotkb:ACLY(gene name)|psi-mi:ACLY(display_short)|uniprotkb:"ATP-citrate (pro-S-)-lyase"(gene name synonym)|uniprotkb:Citrate cleavage enzyme(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480413|imex:IM-26985-103 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750 refseq:NP_001087.2|refseq:NP_942127.1|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002020(Citrate synthase-like)|interpro:IPR003781(CoA-binding)|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR014608(ATP-citrate synthase)|ensembl:ENSG00000131473(gene)|ensembl:ENST00000352035(transcript)|ensembl:ENST00000590151(transcript)|go:"GO:0003878"(ATP citrate synthase activity)|interpro:IPR016102(Succinyl-CoA synthetase-like)|go:"GO:0005524"(ATP binding)|interpro:IPR016143(Citrate synthase-like, small alpha subdomain)|interpro:IPR017440(ATP-citrate lyase/succinyl-CoA ligase, active site)|interpro:IPR017866|interpro:IPR032263|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006085"(acetyl-CoA biosynthetic process)|go:"GO:0006101"(citrate metabolic process)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0046872"(metal ion binding)|interpro:IPR033847|rcsb pdb:6O0H|interpro:IPR036291|rcsb pdb:6POE|interpro:IPR036969|rcsb pdb:6POF|rcsb pdb:6QFB|mint:P53396|rcsb pdb:6UI9|rcsb pdb:6UIA|rcsb pdb:3MWD|rcsb pdb:6UUW|rcsb pdb:6UUZ|rcsb pdb:6UV5|rcsb pdb:6Z2H|rcsb pdb:7LIW|rcsb pdb:7LJ9|rcsb pdb:7LLA|reactome:R-HSA-163765|rcsb pdb:3MWE|reactome:R-HSA-6798695|reactome:R-HSA-75105|rcsb pdb:3PFF|rcsb pdb:5TDE|rcsb pdb:5TDF|rcsb pdb:5TDM|rcsb pdb:5TDZ|rcsb pdb:5TE1|rcsb pdb:5TEQ|rcsb pdb:5TES|rcsb pdb:5TET|rcsb pdb:6HXH|rcsb pdb:6HXK|rcsb pdb:6HXL|rcsb pdb:6HXM|refseq:XP_005257452.1|refseq:NP_001290203.1|refseq:NP_001290204.1 - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rogid:NaxO5aRi08GTrEV9aIboUdTlpAs9606 rigid:VP+vsXKNjGNsAvmRbmlfyFjcswo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969R5 uniprotkb:Q14188 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 intact:EBI-752268|uniprotkb:Q13331|uniprotkb:Q14187|uniprotkb:Q6R754|uniprotkb:Q8WU88|uniprotkb:F8WAI2|uniprotkb:Q9UG28|uniprotkb:D3DNG1|uniprotkb:B7Z8L5|uniprotkb:B7Z8C8|uniprotkb:E9PFC3|ensembl:ENSP00000420616 psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:tfdp2_human(display_long)|uniprotkb:E2F dimerization partner 2(gene name synonym)|uniprotkb:TFDP2(gene name)|psi-mi:TFDP2(display_short)|uniprotkb:DP2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480413|imex:IM-26985-103 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750 refseq:NP_001171609.1|refseq:NP_001171610.1|refseq:NP_006277.1|refseq:NP_001171612.1|refseq:NP_001171613.1|refseq:NP_001171611.1|refseq:XP_016862580.1|refseq:XP_016862585.1|refseq:XP_016862586.1|refseq:XP_016862587.1|refseq:XP_016862588.1|dip:DIP-294N|ensembl:ENSG00000114126(gene)|ensembl:ENST00000489671(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14188|rcsb pdb:1CF7|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9616222|reactome:R-HSA-9661069 - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rogid:Y+N26+kjBjMVwXdL4AEp0Sc1rYY9606 rigid:VP+vsXKNjGNsAvmRbmlfyFjcswo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969R5 uniprotkb:Q99496 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480413|imex:IM-26985-103 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750 refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 - - comment:"author score: 36" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rigid:VP+vsXKNjGNsAvmRbmlfyFjcswo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969R5 uniprotkb:P61244 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480413|imex:IM-26985-103 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750 refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750 - - comment:"author score: 44" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rogid:I5d1d/zT353OsLios95yEITNoWU9606 rigid:VP+vsXKNjGNsAvmRbmlfyFjcswo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969R5 uniprotkb:P83916 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480413|imex:IM-26985-103 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750 ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N - - comment:"author score: 54" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rigid:VP+vsXKNjGNsAvmRbmlfyFjcswo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969R5 uniprotkb:P61964 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480413|imex:IM-26985-103 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750 refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N - - comment:"author score: 61" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rigid:VP+vsXKNjGNsAvmRbmlfyFjcswo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969R5 uniprotkb:Q8IWI9 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 intact:EBI-2815196|uniprotkb:E7ENI0|uniprotkb:F5H7K2|uniprotkb:Q9H9N7|uniprotkb:Q9H8R3|uniprotkb:Q9Y4E9|uniprotkb:Q9UG69|intact:EBI-11143500|intact:EBI-10969960|ensembl:ENSP00000219905|uniprotkb:B9EGR5 psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:mgap_human(display_long)|uniprotkb:MGA(gene name)|psi-mi:MGA(display_short)|uniprotkb:KIAA0518(gene name synonym)|uniprotkb:MAD5(gene name synonym)|uniprotkb:MAX dimerization protein 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480413|imex:IM-26985-103 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750 refseq:NP_001074010.2|ensembl:ENSP00000219905|ensembl:ENST00000566586|ensembl:ENSP00000456141|ensembl:ENSG00000174197(gene)|ensembl:ENST00000219905(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR018186|interpro:IPR032060|interpro:IPR036638|interpro:IPR036960|interpro:IPR037935|mint:Q8IWI9|reactome:R-HSA-8953750|refseq:NP_001157745.1|dip:DIP-57615N - - comment:"author score: 78" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rogid:P4lo9EteCvikQQk5kyVkcobitLU9606 rigid:VP+vsXKNjGNsAvmRbmlfyFjcswo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969R5 uniprotkb:O75461 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480413|imex:IM-26985-103 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750 refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198 - - comment:"author score: 79" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rigid:VP+vsXKNjGNsAvmRbmlfyFjcswo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969R5 uniprotkb:Q9BYE7 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480413|imex:IM-26985-103 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750 refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N - - comment:"author score: 99" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 rigid:VP+vsXKNjGNsAvmRbmlfyFjcswo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NA19 uniprotkb:P23526 intact:EBI-8833581|uniprotkb:A8MTL8|uniprotkb:Q8IXS3|ensembl:ENSP00000382976 intact:EBI-1053240|uniprotkb:Q96A36|ensembl:ENSP00000217426|uniprotkb:B3KUN3|uniprotkb:F5H737|uniprotkb:A8K307|uniprotkb:E1P5P2 psi-mi:lmbl4_human(display_long)|uniprotkb:L3MBTL4(gene name)|psi-mi:L3MBTL4(display_short) psi-mi:sahh_human(display_long)|uniprotkb:S-adenosyl-L-homocysteine hydrolase(gene name synonym)|uniprotkb:AHCY(gene name)|psi-mi:AHCY(display_short)|uniprotkb:SAHH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480473|imex:IM-26985-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524063.1|refseq:NP_775735.2|ensembl:ENSG00000154655(gene)|ensembl:ENST00000400105(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q8NA19|interpro:IPR002515(Zinc finger, C2HC-type) refseq:NP_000678.1|refseq:NP_001155238.1|ensembl:ENSG00000101444(gene)|ensembl:ENST00000217426(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0002439"(chronic inflammatory response to antigenic stimulus)|go:"GO:0004013"(adenosylhomocysteinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0019510"(S-adenosylhomocysteine catabolic process)|go:"GO:0030554"(adenyl nucleotide binding)|go:"GO:0033353"(S-adenosylmethionine cycle)|go:"GO:0042470"(melanosome)|go:"GO:0042745"(circadian sleep/wake cycle)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000043(S-adenosyl-L-homocysteine hydrolase)|interpro:IPR015878(S-adenosyl-L-homocysteine hydrolase, NAD binding)|interpro:IPR020082|interpro:IPR036291|interpro:IPR042172|mint:P23526|rcsb pdb:1A7A|rcsb pdb:1LI4|refseq:XP_011526961.1|refseq:XP_005260374.1|refseq:NP_001309013.1|refseq:NP_001309014.1|rcsb pdb:3NJ4|rcsb pdb:4PFJ|rcsb pdb:4PGF|rcsb pdb:4YVF|rcsb pdb:5W49|rcsb pdb:5W4B|reactome:R-HSA-156581|reactome:R-HSA-1614635|reactome:R-HSA-2408508|reactome:R-HSA-5578997|refseq:XP_016883197.1|refseq:XP_016883198.1|dip:DIP-50557N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:3aoPBOJi3Hx/m4yM6uJ6h73p5949606 rogid:+y7rwgw9EIMaVrkt4/9kbZM44sg9606 rigid:UEAyph+q468EbSfNJQ0eLjcRCIs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NA19 uniprotkb:P36404 intact:EBI-8833581|uniprotkb:A8MTL8|uniprotkb:Q8IXS3|ensembl:ENSP00000382976 intact:EBI-752365|uniprotkb:Q9BUK8|uniprotkb:G3V184|ensembl:ENSP00000246747|ensembl:ENSP00000436021 psi-mi:lmbl4_human(display_long)|uniprotkb:L3MBTL4(gene name)|psi-mi:L3MBTL4(display_short) psi-mi:arl2_human(display_long)|uniprotkb:ARL2(gene name)|psi-mi:ARL2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480473|imex:IM-26985-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524063.1|refseq:NP_775735.2|ensembl:ENSG00000154655(gene)|ensembl:ENST00000400105(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q8NA19|interpro:IPR002515(Zinc finger, C2HC-type) refseq:NP_001186674.1|refseq:NP_001658.2|dip:DIP-47535N|ensembl:ENSG00000213465(gene)|ensembl:ENST00000246747(transcript)|ensembl:ENST00000529384(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007098"(centrosome cycle)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019003"(GDP binding)|go:"GO:0031113"(regulation of microtubule polymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070830"(bicellular tight junction assembly)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|interpro:IPR044612|mint:P36404|rcsb pdb:3DOE|rcsb pdb:3DOF|reactome:R-HSA-389977|reactome:R-HSA-83936|reactome:R-HSA-9648002 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:3aoPBOJi3Hx/m4yM6uJ6h73p5949606 rogid:ArQxx65a8vITU2O0Kr0Qo0hqiqU9606 rigid:UEAyph+q468EbSfNJQ0eLjcRCIs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NA19 uniprotkb:Q9Y468 intact:EBI-8833581|uniprotkb:A8MTL8|uniprotkb:Q8IXS3|ensembl:ENSP00000382976 intact:EBI-1265089|uniprotkb:B4DRC9|uniprotkb:E1P5W7|uniprotkb:Q5H8Y9|uniprotkb:Q5H8Y8|uniprotkb:Q8IUV7|uniprotkb:Q9H1E6|uniprotkb:Q9H1G5|uniprotkb:Q9UG06|uniprotkb:Q9UJB9|uniprotkb:Q9Y4C9|ensembl:ENSP00000402107 psi-mi:lmbl4_human(display_long)|uniprotkb:L3MBTL4(gene name)|psi-mi:L3MBTL4(display_short) psi-mi:lmbl1_human(display_long)|uniprotkb:L3MBTL1(gene name)|psi-mi:L3MBTL1(display_short)|uniprotkb:KIAA0681(gene name synonym)|uniprotkb:L3MBT(gene name synonym)|uniprotkb:L3MBTL1(gene name synonym)|uniprotkb:"L(3)mbt protein homolog"(gene name synonym)|uniprotkb:L3MBTL(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480473|imex:IM-26985-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524063.1|refseq:NP_775735.2|ensembl:ENSG00000154655(gene)|ensembl:ENST00000400105(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q8NA19|interpro:IPR002515(Zinc finger, C2HC-type) refseq:NP_056293.4|refseq:NP_115479.4|dip:DIP-29628N|ensembl:ENSG00000185513(gene)|ensembl:ENST00000427442(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031493"(obsolete nucleosomal histone binding)|go:"GO:0032093"(SAM domain binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR036060|mint:Q9Y468|rcsb pdb:1OYX|rcsb pdb:1OZ2|rcsb pdb:1OZ3|rcsb pdb:2PQW|rcsb pdb:2RHI|rcsb pdb:2RHU|rcsb pdb:2RHX|rcsb pdb:2RHY|rcsb pdb:2RHZ|rcsb pdb:2RI2|rcsb pdb:2RI3|rcsb pdb:2RI5|rcsb pdb:2RJC|rcsb pdb:2RJD|rcsb pdb:2RJE|rcsb pdb:2RJF|rcsb pdb:3OQ5|rcsb pdb:3P8H|rcsb pdb:3UWN|rcsb pdb:6BYB|reactome:R-HSA-6804760|go:"GO:0003682"(chromatin binding) - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:3aoPBOJi3Hx/m4yM6uJ6h73p5949606 rogid:hLkGs3Aq9xKCwsdSghESzw3LYcQ9606 rigid:UEAyph+q468EbSfNJQ0eLjcRCIs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NA19 uniprotkb:P52209 intact:EBI-8833581|uniprotkb:A8MTL8|uniprotkb:Q8IXS3|ensembl:ENSP00000382976 intact:EBI-372761|uniprotkb:Q9BWD8|intact:EBI-11020895|uniprotkb:A8K2Y9|ensembl:ENSP00000270776|uniprotkb:B4DQJ8 psi-mi:lmbl4_human(display_long)|uniprotkb:L3MBTL4(gene name)|psi-mi:L3MBTL4(display_short) psi-mi:6pgd_human(display_long)|uniprotkb:PGD(gene name)|psi-mi:PGD(display_short)|uniprotkb:PGDH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480473|imex:IM-26985-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524063.1|refseq:NP_775735.2|ensembl:ENSG00000154655(gene)|ensembl:ENST00000400105(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q8NA19|interpro:IPR002515(Zinc finger, C2HC-type) refseq:NP_001291380.1|refseq:NP_001291381.1|refseq:NP_002622.2|ensembl:ENSG00000142657(gene)|ensembl:ENST00000270776(transcript)|go:"GO:0004616"("phosphogluconate dehydrogenase (decarboxylating) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0009051"(pentose-phosphate shunt, oxidative branch)|go:"GO:0019322"(pentose biosynthetic process)|go:"GO:0046177"(D-gluconate catabolic process)|go:"GO:0050661"(NADP binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006113(6-phosphogluconate dehydrogenase, decarboxylating)|interpro:IPR006114(6-phosphogluconate dehydrogenase, C-terminal)|interpro:IPR006115(6-phosphogluconate dehydrogenase, NAD-binding)|interpro:IPR006183(6-phosphogluconate dehydrogenase)|interpro:IPR006184(6-phosphogluconate-binding site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR013328(Dehydrogenase, multihelical)|mint:P52209|rcsb pdb:2JKV|rcsb pdb:4GWG|rcsb pdb:4GWK|rcsb pdb:5UQ9|reactome:R-HSA-71336|interpro:IPR036291 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:3aoPBOJi3Hx/m4yM6uJ6h73p5949606 rogid:SgbOgCLmdWm3QnN6fQfkHG6iunw9606 rigid:UEAyph+q468EbSfNJQ0eLjcRCIs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NA19 uniprotkb:O14556 intact:EBI-8833581|uniprotkb:A8MTL8|uniprotkb:Q8IXS3|ensembl:ENSP00000382976 intact:EBI-1057431|uniprotkb:O60823|uniprotkb:Q6JTT9|uniprotkb:Q9HCU6|uniprotkb:B2RC82|ensembl:ENSP00000222286 psi-mi:lmbl4_human(display_long)|uniprotkb:L3MBTL4(gene name)|psi-mi:L3MBTL4(display_short) psi-mi:g3pt_human(display_long)|uniprotkb:GAPDHS(gene name)|psi-mi:GAPDHS(display_short)|uniprotkb:GAPD2(gene name synonym)|uniprotkb:GAPDH2(gene name synonym)|uniprotkb:GAPDS(gene name synonym)|uniprotkb:HSD35(orf name)|uniprotkb:HSD-35(orf name)|uniprotkb:Spermatogenic glyceraldehyde-3-phosphate dehydrogenase(gene name synonym)|uniprotkb:Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480473|imex:IM-26985-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524063.1|refseq:NP_775735.2|ensembl:ENSG00000154655(gene)|ensembl:ENST00000400105(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q8NA19|interpro:IPR002515(Zinc finger, C2HC-type) refseq:NP_055179.1|ensembl:ENSG00000105679(gene)|ensembl:ENST00000222286(transcript)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0050661"(NADP binding)|go:"GO:0051287"(NAD binding)|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|interpro:IPR020831|interpro:IPR036291|mint:O14556|rcsb pdb:3H9E|rcsb pdb:3PFW|rcsb pdb:5C7L|rcsb pdb:5C7O|reactome:R-HSA-390471|reactome:R-HSA-70171|reactome:R-HSA-70263 - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:3aoPBOJi3Hx/m4yM6uJ6h73p5949606 rogid:R2wl89TyWYfD57yzx6up8t7LfDE9606 rigid:UEAyph+q468EbSfNJQ0eLjcRCIs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NA19 uniprotkb:P58557 intact:EBI-8833581|uniprotkb:A8MTL8|uniprotkb:Q8IXS3|ensembl:ENSP00000382976 intact:EBI-2114647|uniprotkb:D3DSN2|uniprotkb:B7WPA9|uniprotkb:B7WPF7|ensembl:ENSP00000329614|ensembl:ENSP00000380805|ensembl:ENSP00000380813 psi-mi:lmbl4_human(display_long)|uniprotkb:L3MBTL4(gene name)|psi-mi:L3MBTL4(display_short) psi-mi:ybey_human(display_long)|uniprotkb:YBEY(gene name)|psi-mi:YBEY(display_short)|uniprotkb:C21orf57(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480473|imex:IM-26985-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524063.1|refseq:NP_775735.2|ensembl:ENSG00000154655(gene)|ensembl:ENST00000400105(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q8NA19|interpro:IPR002515(Zinc finger, C2HC-type) refseq:NP_478061.1|refseq:NP_001300951.1|refseq:NP_001300952.1|refseq:NP_001300953.1|refseq:NP_001300954.1|refseq:NP_001300955.1|ensembl:ENSG00000182362(gene)|ensembl:ENST00000329319(transcript)|ensembl:ENST00000397691(transcript)|ensembl:ENST00000397701(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0006364"(rRNA processing)|go:"GO:0046872"(metal ion binding)|interpro:IPR002036(Protein of unknown function UPF0054)|interpro:IPR020549|interpro:IPR023091|mint:P58557 - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:3aoPBOJi3Hx/m4yM6uJ6h73p5949606 rogid:VOjeUF0iThxy1T2ywZGHB8ILorc9606 rigid:UEAyph+q468EbSfNJQ0eLjcRCIs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NA19 uniprotkb:O15305 intact:EBI-8833581|uniprotkb:A8MTL8|uniprotkb:Q8IXS3|ensembl:ENSP00000382976 intact:EBI-10182608|uniprotkb:D3DUF3|uniprotkb:B7Z6R0|uniprotkb:A8K672|ensembl:ENSP00000268261 psi-mi:lmbl4_human(display_long)|uniprotkb:L3MBTL4(gene name)|psi-mi:L3MBTL4(display_short) psi-mi:pmm2_human(display_long)|uniprotkb:PMM2(gene name)|psi-mi:PMM2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480473|imex:IM-26985-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524063.1|refseq:NP_775735.2|ensembl:ENSG00000154655(gene)|ensembl:ENST00000400105(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q8NA19|interpro:IPR002515(Zinc finger, C2HC-type) refseq:NP_000294.1|ensembl:ENSG00000140650(gene)|ensembl:ENST00000268261(transcript)|go:"GO:0004615"(phosphomannomutase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006013"(mannose metabolic process)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0009298"(GDP-mannose biosynthetic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046872"(metal ion binding)|interpro:IPR005002(Eukaryotic phosphomannomutase)|interpro:IPR006379(HAD-superfamily hydrolase, subfamily IIB)|interpro:IPR023214|interpro:IPR036412|interpro:IPR043169|mint:O15305|rcsb pdb:2AMY|rcsb pdb:2Q4R|reactome:R-HSA-4043911|reactome:R-HSA-446205 - - comment:"author score: 30" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:3aoPBOJi3Hx/m4yM6uJ6h73p5949606 rogid:3PhPMapZgZUgnd1/ddww/ciXQKU9606 rigid:UEAyph+q468EbSfNJQ0eLjcRCIs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NA19 uniprotkb:P0CG04 intact:EBI-8833581|uniprotkb:A8MTL8|uniprotkb:Q8IXS3|ensembl:ENSP00000382976 intact:EBI-1221063|uniprotkb:P80423|uniprotkb:A0M8Q4|uniprotkb:P01842|uniprotkb:A0A075B6K8 psi-mi:lmbl4_human(display_long)|uniprotkb:L3MBTL4(gene name)|psi-mi:L3MBTL4(display_short) psi-mi:iglc1_human(display_long)|uniprotkb:IGLC1(gene name)|psi-mi:IGLC1(display_short)|uniprotkb:Ig lambda chain C region MGC(gene name synonym)|uniprotkb:Ig lambda-1 chain C region(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480473|imex:IM-26985-31 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524063.1|refseq:NP_775735.2|ensembl:ENSG00000154655(gene)|ensembl:ENST00000400105(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q8NA19|interpro:IPR002515(Zinc finger, C2HC-type) interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|mint:P0CG04|interpro:IPR036179|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0034987"(immunoglobulin receptor binding)|go:"GO:0042571"(immunoglobulin complex, circulating)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|rcsb pdb:1ZVO|rcsb pdb:2FB4|rcsb pdb:2IG2|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|go:"GO:0045087"(innate immune response)|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664422|reactome:R-HSA-977606|reactome:R-HSA-983695|reactome:R-HSA-9664323 - - comment:"author score: 46" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:3aoPBOJi3Hx/m4yM6uJ6h73p5949606 rogid:OOdxBXPI2Jzf9HxurFZjk3/L1DM9606 rigid:UEAyph+q468EbSfNJQ0eLjcRCIs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q03252 uniprotkb:P02545 intact:EBI-2830427|uniprotkb:O75292|uniprotkb:Q14734|uniprotkb:Q96DF6|ensembl:ENSP00000327054|intact:EBI-11044751|intact:EBI-20728818 intact:EBI-351935|uniprotkb:B4DI32|uniprotkb:E7EUI9|uniprotkb:P02546|uniprotkb:Q969I8|uniprotkb:Q96JA2|uniprotkb:D6RAQ3|uniprotkb:Q5I6Y4|uniprotkb:Q5I6Y6|uniprotkb:Q6UYC3|uniprotkb:Q5TCJ2|uniprotkb:Q5TCJ3|uniprotkb:D3DVB0|intact:EBI-28988787|ensembl:ENSP00000355292|ensembl:ENSP00000357283|ensembl:ENSP00000502256|ensembl:ENSP00000506771 psi-mi:lmnb2_human(display_long)|uniprotkb:LMNB2(gene name)|psi-mi:LMNB2(display_short)|uniprotkb:LMN2(gene name synonym) psi-mi:lmna_human(display_long)|uniprotkb:LMNA(gene name)|psi-mi:LMNA(display_short)|uniprotkb:LMN1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25480581|imex:IM-26985-413 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000176619(gene)|ensembl:ENST00000325327(transcript)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005882"(intermediate filament)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042802"(identical protein binding)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|mint:Q03252|rcsb pdb:2LLL|rcsb pdb:5BNW|refseq:NP_116126.3|dip:DIP-57724N refseq:NP_005563.1|refseq:NP_733821.1|refseq:NP_733822.1|refseq:NP_001244303.1|refseq:NP_001269553.1|refseq:NP_001269554.1|refseq:NP_001269555.1|ensembl:ENSG00000160789(gene)|ensembl:ENST00000361308(transcript)|ensembl:ENST00000368300(transcript)|ensembl:ENST00000675939(transcript)|ensembl:ENST00000683032(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005634"(nucleus)|go:"GO:0005638"(lamin filament)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0007517"(muscle organ development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055015"(ventricular cardiac muscle cell development)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0072201"(negative regulation of mesenchymal cell proliferation)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1990683"(DNA double-strand break attachment to nuclear envelope)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001322(Intermediate filament, C-terminal)|interpro:IPR018039|interpro:IPR036415|interpro:IPR039008|mint:P02545|rcsb pdb:1IFR|rcsb pdb:1IVT|rcsb pdb:1X8Y|rcsb pdb:2XV5|rcsb pdb:2YPT|rcsb pdb:3GEF|rcsb pdb:3V4Q|rcsb pdb:3V4W|rcsb pdb:3V5B|rcsb pdb:6GHD|rcsb pdb:6JLB|rcsb pdb:6RPR|rcsb pdb:6SNZ|rcsb pdb:6YF5|rcsb pdb:6YJD|reactome:R-HSA-1221632|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-352238|reactome:R-HSA-381038|reactome:R-HSA-4419969|reactome:R-HSA-6802952|reactome:R-HSA-8862803|ensembl:ENSP00000503633|ensembl:ENST00000682650|ensembl:ENSP00000506904|ensembl:ENST00000677389|ensembl:ENSP00000506771|ensembl:ENSP00000355292|ensembl:ENST00000368299|ensembl:ENSP00000357282|ensembl:ENSP00000357283|ensembl:ENST00000368301|ensembl:ENSP00000357284|ensembl:ENST00000448611|ensembl:ENSP00000395597|ensembl:ENST00000473598|ensembl:ENSP00000421821|ensembl:ENSP00000502256|ensembl:ENST00000676385|ensembl:ENSP00000502091|dip:DIP-32948N|dip:DIP-58162N - comment:"author score: 25" - figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Jt7rEo5Br8HidU+VAc0L6rtBU889606 rogid:OS/QDFLGOD2PElQ6mCpBtk6xh/09606 rigid:mQxqByHbVMxx3Xbp2ECYh/LrUsc false - tandem tag:n-n - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H9Z2 uniprotkb:P81605 intact:EBI-2462365|ensembl:ENSP00000254231|ensembl:ENSP00000363314 intact:EBI-395625|uniprotkb:P58461|uniprotkb:A5JHP2|uniprotkb:A5JHP3|uniprotkb:Q53YJ2|ensembl:ENSP00000293371 psi-mi:ln28a_human(display_long)|uniprotkb:LIN28A(gene name)|psi-mi:LIN28A(display_short)|uniprotkb:CSDD1(gene name synonym)|uniprotkb:LIN28(gene name synonym)|uniprotkb:ZCCHC1(gene name synonym)|uniprotkb:Zinc finger CCHC domain-containing protein 1(gene name synonym) psi-mi:dcd_human(display_long)|uniprotkb:AIDD(gene name synonym)|uniprotkb:DSEP(gene name synonym)|uniprotkb:Preproteolysin(gene name synonym)|uniprotkb:DCD(gene name)|psi-mi:DCD(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480521|imex:IM-26985-553 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540450.1|refseq:NP_078950.1|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0035198"(miRNA binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045686"(negative regulation of glial cell differentiation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071076"(RNA 3' uridylation)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:1901724"(positive regulation of cell proliferation involved in kidney development)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1905538"(polysome binding)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036875|mint:Q9H9Z2|rcsb pdb:2CQF|rcsb pdb:2LI8|rcsb pdb:5UDZ|reactome:R-HSA-452723|ensembl:ENSG00000131914(gene)|ensembl:ENST00000254231(transcript)|ensembl:ENST00000326279(transcript)|go:"GO:0000932"(P-body)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0031123"(RNA 3'-end processing) refseq:NP_444513.1|refseq:NP_001287783.1|ensembl:ENSG00000161634(gene)|ensembl:ENST00000293371(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008233"(peptidase activity)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR028130|interpro:IPR043557|mint:P81605|rcsb pdb:2KSG|rcsb pdb:2NDK|rcsb pdb:2YMK|rcsb pdb:6SHK|reactome:R-HSA-6803157 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+74ZEfwOtT0fztME4RpHlyYIlww9606 rogid:M8PkKVWx98nhtd79ods05mqw8Ls9606 rigid:QGPE2/NeTz45rv5KYDV7s/8IwvQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H9Z2 uniprotkb:P10412 intact:EBI-2462365|ensembl:ENSP00000254231|ensembl:ENSP00000363314 intact:EBI-358163|uniprotkb:Q4VB25|ensembl:ENSP00000307705 psi-mi:ln28a_human(display_long)|uniprotkb:LIN28A(gene name)|psi-mi:LIN28A(display_short)|uniprotkb:CSDD1(gene name synonym)|uniprotkb:LIN28(gene name synonym)|uniprotkb:ZCCHC1(gene name synonym)|uniprotkb:Zinc finger CCHC domain-containing protein 1(gene name synonym) psi-mi:h14_human(display_long)|uniprotkb:H1-4(gene name)|psi-mi:H1-4(display_short)|uniprotkb:H1F4(gene name synonym)|uniprotkb:HIST1H1E(gene name synonym)|uniprotkb:Histone H1b(gene name synonym)|uniprotkb:Histone H1s-4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480521|imex:IM-26985-553 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540450.1|refseq:NP_078950.1|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0035198"(miRNA binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045686"(negative regulation of glial cell differentiation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071076"(RNA 3' uridylation)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:1901724"(positive regulation of cell proliferation involved in kidney development)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1905538"(polysome binding)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036875|mint:Q9H9Z2|rcsb pdb:2CQF|rcsb pdb:2LI8|rcsb pdb:5UDZ|reactome:R-HSA-452723|ensembl:ENSG00000131914(gene)|ensembl:ENST00000254231(transcript)|ensembl:ENST00000326279(transcript)|go:"GO:0000932"(P-body)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0031123"(RNA 3'-end processing) refseq:NP_005312.1|rcsb pdb:6H8P|rcsb pdb:7K5Y|rcsb pdb:7K63|go:"GO:0032564"(dATP binding)|go:"GO:0043531"(ADP binding)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P10412|rcsb pdb:3TZD|rcsb pdb:5JJZ|reactome:R-HSA-140342|reactome:R-HSA-2559584|ensembl:ENSG00000168298(gene)|ensembl:ENST00000304218(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0000792"(heterochromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016208"(AMP binding)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing) - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+74ZEfwOtT0fztME4RpHlyYIlww9606 rogid:yT8wBbspLLR8G3DrgpFeWEOPgac9606 rigid:QGPE2/NeTz45rv5KYDV7s/8IwvQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H9Z2 uniprotkb:O00425 intact:EBI-2462365|ensembl:ENSP00000254231|ensembl:ENSP00000363314 intact:EBI-1058566|ensembl:ENSP00000258729|uniprotkb:Q63HM0|uniprotkb:A0A4Z5|uniprotkb:Q6MZZ2|uniprotkb:Q86VB1|intact:EBI-2560196 psi-mi:ln28a_human(display_long)|uniprotkb:LIN28A(gene name)|psi-mi:LIN28A(display_short)|uniprotkb:CSDD1(gene name synonym)|uniprotkb:LIN28(gene name synonym)|uniprotkb:ZCCHC1(gene name synonym)|uniprotkb:Zinc finger CCHC domain-containing protein 1(gene name synonym) psi-mi:if2b3_human(display_long)|uniprotkb:IGF2BP3(gene name)|psi-mi:IGF2BP3(display_short)|uniprotkb:IMP3(gene name synonym)|uniprotkb:KOC1(gene name synonym)|uniprotkb:VICKZ3(gene name synonym)|uniprotkb:IGF-II mRNA-binding protein 3(gene name synonym)|uniprotkb:KH domain-containing protein overexpressed in cancer(gene name synonym)|uniprotkb:VICKZ family member 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480521|imex:IM-26985-553 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540450.1|refseq:NP_078950.1|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0035198"(miRNA binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045686"(negative regulation of glial cell differentiation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071076"(RNA 3' uridylation)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:1901724"(positive regulation of cell proliferation involved in kidney development)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1905538"(polysome binding)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036875|mint:Q9H9Z2|rcsb pdb:2CQF|rcsb pdb:2LI8|rcsb pdb:5UDZ|reactome:R-HSA-452723|ensembl:ENSG00000131914(gene)|ensembl:ENST00000254231(transcript)|ensembl:ENST00000326279(transcript)|go:"GO:0000932"(P-body)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0031123"(RNA 3'-end processing) ensembl:ENSG00000136231(gene)|ensembl:ENST00000258729(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0007399"(nervous system development)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0045182"(translation regulator activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051252"(regulation of RNA metabolic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|refseq:NP_006538.2|interpro:IPR004087(K Homology)|dip:DIP-44171N|interpro:IPR004088(K Homology, type 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034844|interpro:IPR035979|interpro:IPR036612|mint:O00425|rcsb pdb:2E44|rcsb pdb:6FQ1|rcsb pdb:6FQR|rcsb pdb:6GQE|rcsb pdb:6GX6|reactome:R-HSA-428359 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+74ZEfwOtT0fztME4RpHlyYIlww9606 rogid:yGEnYHFP+P05J45ZnHUdcPXHlQA9606 rigid:QGPE2/NeTz45rv5KYDV7s/8IwvQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H9Z2 uniprotkb:P62899 intact:EBI-2462365|ensembl:ENSP00000254231|ensembl:ENSP00000363314 intact:EBI-1053664|intact:EBI-3867511|uniprotkb:B7Z4K2|uniprotkb:P12947|uniprotkb:Q53SQ5|uniprotkb:Q6LBJ6|uniprotkb:D3DVJ4|uniprotkb:Q6IRZ0|ensembl:ENSP00000264258|ensembl:ENSP00000386681 psi-mi:ln28a_human(display_long)|uniprotkb:LIN28A(gene name)|psi-mi:LIN28A(display_short)|uniprotkb:CSDD1(gene name synonym)|uniprotkb:LIN28(gene name synonym)|uniprotkb:ZCCHC1(gene name synonym)|uniprotkb:Zinc finger CCHC domain-containing protein 1(gene name synonym) psi-mi:rl31_human(display_long)|uniprotkb:RPL31(gene name)|psi-mi:RPL31(display_short)|uniprotkb:Large ribosomal subunit protein eL31(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480521|imex:IM-26985-553 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540450.1|refseq:NP_078950.1|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0035198"(miRNA binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045686"(negative regulation of glial cell differentiation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071076"(RNA 3' uridylation)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:1901724"(positive regulation of cell proliferation involved in kidney development)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1905538"(polysome binding)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036875|mint:Q9H9Z2|rcsb pdb:2CQF|rcsb pdb:2LI8|rcsb pdb:5UDZ|reactome:R-HSA-452723|ensembl:ENSG00000131914(gene)|ensembl:ENST00000254231(transcript)|ensembl:ENST00000326279(transcript)|go:"GO:0000932"(P-body)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0031123"(RNA 3'-end processing) refseq:NP_000984.1|refseq:NP_001092047.1|refseq:NP_001093163.1|ensembl:ENSG00000071082(gene)|ensembl:ENST00000264258(transcript)|ensembl:ENST00000409733(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000054(Ribosomal protein L31e)|interpro:IPR020052|interpro:IPR023621|mint:P62899|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+74ZEfwOtT0fztME4RpHlyYIlww9606 rogid:77LFR7/2somk6blVogZf1XFdJLk9606 rigid:QGPE2/NeTz45rv5KYDV7s/8IwvQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H9Z2 uniprotkb:P47914 intact:EBI-2462365|ensembl:ENSP00000254231|ensembl:ENSP00000363314 intact:EBI-714039|uniprotkb:Q6IPY3|ensembl:ENSP00000418346|ensembl:ENSP00000418868|ensembl:ENSP00000420673|ensembl:ENSP00000294189|ensembl:ENSP00000417048|ensembl:ENSP00000418153|uniprotkb:B2R4M8|uniprotkb:A8K0H3 psi-mi:ln28a_human(display_long)|uniprotkb:LIN28A(gene name)|psi-mi:LIN28A(display_short)|uniprotkb:CSDD1(gene name synonym)|uniprotkb:LIN28(gene name synonym)|uniprotkb:ZCCHC1(gene name synonym)|uniprotkb:Zinc finger CCHC domain-containing protein 1(gene name synonym) psi-mi:rl29_human(display_long)|uniprotkb:Cell surface heparin-binding protein HIP(gene name synonym)|uniprotkb:RPL29(gene name)|psi-mi:RPL29(display_short)|uniprotkb:Large ribosomal subunit protein eL29(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480521|imex:IM-26985-553 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540450.1|refseq:NP_078950.1|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0035198"(miRNA binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045686"(negative regulation of glial cell differentiation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071076"(RNA 3' uridylation)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:1901724"(positive regulation of cell proliferation involved in kidney development)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1905538"(polysome binding)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036875|mint:Q9H9Z2|rcsb pdb:2CQF|rcsb pdb:2LI8|rcsb pdb:5UDZ|reactome:R-HSA-452723|ensembl:ENSG00000131914(gene)|ensembl:ENST00000254231(transcript)|ensembl:ENST00000326279(transcript)|go:"GO:0000932"(P-body)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0031123"(RNA 3'-end processing) ensembl:ENST00000294189(transcript)|ensembl:ENST00000466397(transcript)|ensembl:ENST00000475248(transcript)|ensembl:ENST00000479017(transcript)|ensembl:ENST00000492277(transcript)|ensembl:ENST00000495383(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0007566"(embryo implantation)|go:"GO:0008201"(heparin binding)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR002673(Ribosomal protein L29e)|mint:P47914|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|ensembl:ENSG00000162244(gene)|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_000983.1|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+74ZEfwOtT0fztME4RpHlyYIlww9606 rogid:XZUSMDDzycAi6QEXYbljXaeVg0U9606 rigid:QGPE2/NeTz45rv5KYDV7s/8IwvQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H9Z2 uniprotkb:Q9NZI8 intact:EBI-2462365|ensembl:ENSP00000254231|ensembl:ENSP00000363314 intact:EBI-1053892|uniprotkb:C9JT33|ensembl:ENSP00000290341 psi-mi:ln28a_human(display_long)|uniprotkb:LIN28A(gene name)|psi-mi:LIN28A(display_short)|uniprotkb:CSDD1(gene name synonym)|uniprotkb:LIN28(gene name synonym)|uniprotkb:ZCCHC1(gene name synonym)|uniprotkb:Zinc finger CCHC domain-containing protein 1(gene name synonym) psi-mi:if2b1_human(display_long)|uniprotkb:ZBP1(gene name synonym)|uniprotkb:IGF-II mRNA-binding protein 1(gene name synonym)|uniprotkb:Coding region determinant-binding protein(gene name synonym)|uniprotkb:VICKZ family member 1(gene name synonym)|uniprotkb:IGF2BP1(gene name)|psi-mi:IGF2BP1(display_short)|uniprotkb:Zipcode-binding protein 1(gene name synonym)|uniprotkb:CRDBP(gene name synonym)|uniprotkb:VICKZ1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480521|imex:IM-26985-553 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540450.1|refseq:NP_078950.1|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0035198"(miRNA binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045686"(negative regulation of glial cell differentiation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071076"(RNA 3' uridylation)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:1901724"(positive regulation of cell proliferation involved in kidney development)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1905538"(polysome binding)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036875|mint:Q9H9Z2|rcsb pdb:2CQF|rcsb pdb:2LI8|rcsb pdb:5UDZ|reactome:R-HSA-452723|ensembl:ENSG00000131914(gene)|ensembl:ENST00000254231(transcript)|ensembl:ENST00000326279(transcript)|go:"GO:0000932"(P-body)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0031123"(RNA 3'-end processing) refseq:NP_006537.3|refseq:NP_001153895.1|ensembl:ENSG00000159217(gene)|ensembl:ENST00000290341(transcript)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007399"(nervous system development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010610"(regulation of mRNA stability involved in response to stress)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022013"(pallium cell proliferation in forebrain)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030426"(growth cone)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0045182"(translation regulator activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051028"(mRNA transport)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0140059"(dendrite arborization)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034837|interpro:IPR034842|interpro:IPR035979|interpro:IPR036612|mint:Q9NZI8|rcsb pdb:3KRM|rcsb pdb:6QEY|reactome:R-HSA-428359|reactome:R-HSA-5687128|dip:DIP-38139N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+74ZEfwOtT0fztME4RpHlyYIlww9606 rogid:3Ps/PWWYr0WpYcx3G/AOiQEj+vc9606 rigid:QGPE2/NeTz45rv5KYDV7s/8IwvQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H9Z2 uniprotkb:Q02878 intact:EBI-2462365|ensembl:ENSP00000254231|ensembl:ENSP00000363314 intact:EBI-359655|uniprotkb:Q2M3Q3|uniprotkb:Q8WW97|ensembl:ENSP00000202773|ensembl:ENSP00000403172 psi-mi:ln28a_human(display_long)|uniprotkb:LIN28A(gene name)|psi-mi:LIN28A(display_short)|uniprotkb:CSDD1(gene name synonym)|uniprotkb:LIN28(gene name synonym)|uniprotkb:ZCCHC1(gene name synonym)|uniprotkb:Zinc finger CCHC domain-containing protein 1(gene name synonym) psi-mi:rl6_human(display_long)|uniprotkb:RPL6(gene name)|psi-mi:RPL6(display_short)|uniprotkb:TXREB1(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 107(gene name synonym)|uniprotkb:Neoplasm-related protein C140(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480521|imex:IM-26985-553 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540450.1|refseq:NP_078950.1|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0035198"(miRNA binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045686"(negative regulation of glial cell differentiation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071076"(RNA 3' uridylation)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:1901724"(positive regulation of cell proliferation involved in kidney development)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1905538"(polysome binding)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036875|mint:Q9H9Z2|rcsb pdb:2CQF|rcsb pdb:2LI8|rcsb pdb:5UDZ|reactome:R-HSA-452723|ensembl:ENSG00000131914(gene)|ensembl:ENST00000254231(transcript)|ensembl:ENST00000326279(transcript)|go:"GO:0000932"(P-body)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0031123"(RNA 3'-end processing) refseq:NP_000961.2|refseq:NP_001019833.1|ensembl:ENSG00000089009(gene)|ensembl:ENST00000202773(transcript)|ensembl:ENST00000424576(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR000915(Ribosomal protein L6E)|interpro:IPR005568(Ribosomal protein L6, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041997|mint:Q02878|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001307066.1|refseq:NP_001307067.1|refseq:NP_001307068.1|refseq:NP_001307069.1|refseq:NP_001307070.1|refseq:XP_016875270.1|refseq:XP_016875271.1|dip:DIP-27547N - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+74ZEfwOtT0fztME4RpHlyYIlww9606 rogid:Y7fx3ToInzucV2QmI8KLSdHxai09606 rigid:QGPE2/NeTz45rv5KYDV7s/8IwvQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H9Z2 uniprotkb:P67809 intact:EBI-2462365|ensembl:ENSP00000254231|ensembl:ENSP00000363314 intact:EBI-354065|uniprotkb:P16990|uniprotkb:P16991|uniprotkb:Q14972|uniprotkb:Q15325|uniprotkb:Q5FVF0|ensembl:ENSP00000361626 psi-mi:ln28a_human(display_long)|uniprotkb:LIN28A(gene name)|psi-mi:LIN28A(display_short)|uniprotkb:CSDD1(gene name synonym)|uniprotkb:LIN28(gene name synonym)|uniprotkb:ZCCHC1(gene name synonym)|uniprotkb:Zinc finger CCHC domain-containing protein 1(gene name synonym) psi-mi:ybox1_human(display_long)|uniprotkb:YBX1(gene name)|psi-mi:YBX1(display_short)|uniprotkb:YB1(gene name synonym)|uniprotkb:NSEP1(gene name synonym)|uniprotkb:Y-box transcription factor(gene name synonym)|uniprotkb:CCAAT-binding transcription factor I subunit A(gene name synonym)|uniprotkb:Enhancer factor I subunit A(gene name synonym)|uniprotkb:DNA-binding protein B(gene name synonym)|uniprotkb:Nuclease-sensitive element-binding protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480521|imex:IM-26985-553 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540450.1|refseq:NP_078950.1|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0035198"(miRNA binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045686"(negative regulation of glial cell differentiation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071076"(RNA 3' uridylation)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:1901724"(positive regulation of cell proliferation involved in kidney development)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1905538"(polysome binding)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036875|mint:Q9H9Z2|rcsb pdb:2CQF|rcsb pdb:2LI8|rcsb pdb:5UDZ|reactome:R-HSA-452723|ensembl:ENSG00000131914(gene)|ensembl:ENST00000254231(transcript)|ensembl:ENST00000326279(transcript)|go:"GO:0000932"(P-body)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0031123"(RNA 3'-end processing) refseq:NP_004550.2|dip:DIP-29405N|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990428"(miRNA transport)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P67809|rcsb pdb:1H95|rcsb pdb:5YTS|rcsb pdb:5YTT|rcsb pdb:5YTV|rcsb pdb:5YTX|rcsb pdb:6A6L|rcsb pdb:6KTC|rcsb pdb:6KUG|rcsb pdb:6LMR|rcsb pdb:6LMS|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-9017802|ensembl:ENSG00000065978(gene)|ensembl:ENST00000321358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0008544"(epidermis development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035198"(miRNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050658"(RNA transport)|go:"GO:0051020"(GTPase binding)|go:"GO:0051031"(tRNA transport)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding) - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+74ZEfwOtT0fztME4RpHlyYIlww9606 rogid:0/mAXOzokPlDByFFzGTP8bp9nqo9606 rigid:QGPE2/NeTz45rv5KYDV7s/8IwvQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H9Z2 uniprotkb:P68363 intact:EBI-2462365|ensembl:ENSP00000254231|ensembl:ENSP00000363314 intact:EBI-487083|intact:EBI-1384226|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:Q27I68|ensembl:ENSP00000336799|uniprotkb:Q8WU19 psi-mi:ln28a_human(display_long)|uniprotkb:LIN28A(gene name)|psi-mi:LIN28A(display_short)|uniprotkb:CSDD1(gene name synonym)|uniprotkb:LIN28(gene name synonym)|uniprotkb:ZCCHC1(gene name synonym)|uniprotkb:Zinc finger CCHC domain-containing protein 1(gene name synonym) psi-mi:tba1b_human(display_long)|uniprotkb:TUBA1B(gene name)|psi-mi:TUBA1B(display_short)|uniprotkb:Tubulin alpha-ubiquitous chain(gene name synonym)|uniprotkb:Alpha-tubulin ubiquitous(gene name synonym)|uniprotkb:Tubulin K-alpha-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480521|imex:IM-26985-553 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540450.1|refseq:NP_078950.1|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0035198"(miRNA binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045686"(negative regulation of glial cell differentiation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071076"(RNA 3' uridylation)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:1901724"(positive regulation of cell proliferation involved in kidney development)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1905538"(polysome binding)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036875|mint:Q9H9Z2|rcsb pdb:2CQF|rcsb pdb:2LI8|rcsb pdb:5UDZ|reactome:R-HSA-452723|ensembl:ENSG00000131914(gene)|ensembl:ENST00000254231(transcript)|ensembl:ENST00000326279(transcript)|go:"GO:0000932"(P-body)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0031123"(RNA 3'-end processing) refseq:NP_006073.2|ensembl:ENSG00000123416(gene)|ensembl:ENST00000336023(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-983189|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|go:"GO:0045121"(membrane raft)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68363|rcsb pdb:2E4H|rcsb pdb:5IJ0|rcsb pdb:5IJ9|rcsb pdb:5N5N|rcsb pdb:6E7B|rcsb pdb:6E7C|rcsb pdb:6I2I|go:"GO:0051301"(cell division)|rcsb pdb:6J4V|rcsb pdb:6J8O|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|rcsb pdb:6S8L|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9013407|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-2132295|reactome:R-HSA-9668328 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+74ZEfwOtT0fztME4RpHlyYIlww9606 rogid:D4YpuLCXl/S+53qV7P7sF81aARY9606 rigid:QGPE2/NeTz45rv5KYDV7s/8IwvQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H9Z2 uniprotkb:P0C0S8 intact:EBI-2462365|ensembl:ENSP00000254231|ensembl:ENSP00000363314 intact:EBI-1390628|uniprotkb:P02261|uniprotkb:Q2M1R2|uniprotkb:Q76PA6|intact:EBI-1642354|ensembl:ENSP00000351589|ensembl:ENSP00000352119|ensembl:ENSP00000352627|ensembl:ENSP00000482431|ensembl:ENSP00000482538 psi-mi:ln28a_human(display_long)|uniprotkb:LIN28A(gene name)|psi-mi:LIN28A(display_short)|uniprotkb:CSDD1(gene name synonym)|uniprotkb:LIN28(gene name synonym)|uniprotkb:ZCCHC1(gene name synonym)|uniprotkb:Zinc finger CCHC domain-containing protein 1(gene name synonym) psi-mi:h2a1_human(display_long)|uniprotkb:H2AC11(gene name)|psi-mi:H2AC11(display_short)|uniprotkb:H2AC13(gene name)|psi-mi:H2AC13(display_short)|uniprotkb:H2AC15(gene name)|psi-mi:H2AC15(display_short)|uniprotkb:H2AC16(gene name)|psi-mi:H2AC16(display_short)|uniprotkb:H2AC17(gene name)|psi-mi:H2AC17(display_short)|uniprotkb:H2AFC(gene name synonym)|uniprotkb:H2AFD(gene name synonym)|uniprotkb:H2AFI(gene name synonym)|uniprotkb:H2AFN(gene name synonym)|uniprotkb:H2AFP(gene name synonym)|uniprotkb:HIST1H2AG(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:HIST1H2AK(gene name synonym)|uniprotkb:HIST1H2AL(gene name synonym)|uniprotkb:HIST1H2AM(gene name synonym)|uniprotkb:Histone H2A/ptl(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480521|imex:IM-26985-553 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540450.1|refseq:NP_078950.1|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0035198"(miRNA binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045686"(negative regulation of glial cell differentiation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071076"(RNA 3' uridylation)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:1901724"(positive regulation of cell proliferation involved in kidney development)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1905538"(polysome binding)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036875|mint:Q9H9Z2|rcsb pdb:2CQF|rcsb pdb:2LI8|rcsb pdb:5UDZ|reactome:R-HSA-452723|ensembl:ENSG00000131914(gene)|ensembl:ENST00000254231(transcript)|ensembl:ENST00000326279(transcript)|go:"GO:0000932"(P-body)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0031123"(RNA 3'-end processing) ensembl:ENSG00000196747(gene)|ensembl:ENSG00000196787(gene)|ensembl:ENSG00000275221(gene)|ensembl:ENSG00000276903(gene)|ensembl:ENSG00000278677(gene)|refseq:NP_003500.1|refseq:NP_003501.1|refseq:NP_003502.1|refseq:NP_003505.1|refseq:NP_066408.1|dip:DIP-39638N|ensembl:ENST00000358739(transcript)|ensembl:ENST00000359193(transcript)|ensembl:ENST00000359611(transcript)|ensembl:ENST00000613174(transcript)|ensembl:ENST00000618958(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0019899"(enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P0C0S8|rcsb pdb:4QYL|rcsb pdb:5KGF|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:7JO9|rcsb pdb:7JOA|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+74ZEfwOtT0fztME4RpHlyYIlww9606 rogid:dpZm9c7r9ihR4gW0TZWsVfXAWJ89606 rigid:QGPE2/NeTz45rv5KYDV7s/8IwvQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H9Z2 uniprotkb:Q6PKG0 intact:EBI-2462365|ensembl:ENSP00000254231|ensembl:ENSP00000363314 intact:EBI-1052114|uniprotkb:O94836|uniprotkb:Q8N4M2|uniprotkb:Q8NB73|uniprotkb:Q9UFD7|ensembl:ENSP00000428589 psi-mi:ln28a_human(display_long)|uniprotkb:LIN28A(gene name)|psi-mi:LIN28A(display_short)|uniprotkb:CSDD1(gene name synonym)|uniprotkb:LIN28(gene name synonym)|uniprotkb:ZCCHC1(gene name synonym)|uniprotkb:Zinc finger CCHC domain-containing protein 1(gene name synonym) psi-mi:larp1_human(display_long)|uniprotkb:La ribonucleoprotein domain family member 1(gene name synonym)|uniprotkb:LARP1(gene name)|psi-mi:LARP1(display_short)|uniprotkb:KIAA0731(gene name synonym)|uniprotkb:LARP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480521|imex:IM-26985-553 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540450.1|refseq:NP_078950.1|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0035198"(miRNA binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045686"(negative regulation of glial cell differentiation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071076"(RNA 3' uridylation)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:1901724"(positive regulation of cell proliferation involved in kidney development)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1905538"(polysome binding)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036875|mint:Q9H9Z2|rcsb pdb:2CQF|rcsb pdb:2LI8|rcsb pdb:5UDZ|reactome:R-HSA-452723|ensembl:ENSG00000131914(gene)|ensembl:ENST00000254231(transcript)|ensembl:ENST00000326279(transcript)|go:"GO:0000932"(P-body)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0031123"(RNA 3'-end processing) refseq:NP_056130.2|ensembl:ENST00000336314|ensembl:ENSP00000336721|ensembl:ENSP00000428589|refseq:XP_005268461.1|ensembl:ENSG00000155506(gene)|ensembl:ENST00000518297(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006413"(translational initiation)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008494"(translation activator activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031929"(TOR signaling)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0072752"(cellular response to rapamycin)|go:"GO:1990928"(response to amino acid starvation)|interpro:IPR006607(Protein of unknown function DM15)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR036388|interpro:IPR036390|mint:Q6PKG0|rcsb pdb:4ZC4|rcsb pdb:5C0V|rcsb pdb:5V4R|rcsb pdb:5V7C|rcsb pdb:5V87|rcsb pdb:6PW3 - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+74ZEfwOtT0fztME4RpHlyYIlww9606 rogid:TjQrZVRN3opAdFIWZtaEopFZf8I9606 rigid:QGPE2/NeTz45rv5KYDV7s/8IwvQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H9Z2 uniprotkb:P62750 intact:EBI-2462365|ensembl:ENSP00000254231|ensembl:ENSP00000363314 intact:EBI-353254|uniprotkb:P29316|uniprotkb:Q92774|uniprotkb:P39024|uniprotkb:B2R5B2|ensembl:ENSP00000389103 psi-mi:ln28a_human(display_long)|uniprotkb:LIN28A(gene name)|psi-mi:LIN28A(display_short)|uniprotkb:CSDD1(gene name synonym)|uniprotkb:LIN28(gene name synonym)|uniprotkb:ZCCHC1(gene name synonym)|uniprotkb:Zinc finger CCHC domain-containing protein 1(gene name synonym) psi-mi:rl23a_human(display_long)|uniprotkb:RPL23A(gene name)|psi-mi:RPL23A(display_short)|uniprotkb:Large ribosomal subunit protein uL23(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480521|imex:IM-26985-553 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540450.1|refseq:NP_078950.1|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0035198"(miRNA binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045686"(negative regulation of glial cell differentiation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071076"(RNA 3' uridylation)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:1901724"(positive regulation of cell proliferation involved in kidney development)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1905538"(polysome binding)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036875|mint:Q9H9Z2|rcsb pdb:2CQF|rcsb pdb:2LI8|rcsb pdb:5UDZ|reactome:R-HSA-452723|ensembl:ENSG00000131914(gene)|ensembl:ENST00000254231(transcript)|ensembl:ENST00000326279(transcript)|go:"GO:0000932"(P-body)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0031123"(RNA 3'-end processing) reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|refseq:NP_000975.2|ensembl:ENSG00000198242(gene)|ensembl:ENST00000422514(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904841"(TORC2 complex binding)|interpro:IPR001014(Ribosomal protein L23, conserved site)|interpro:IPR005633(Ribosomal protein L23/L25, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR013025(Ribosomal protein L25/L23)|interpro:IPR019985|mint:P62750|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+74ZEfwOtT0fztME4RpHlyYIlww9606 rogid:lA1ubRFO9/Tl54Z1dKUzoCKvpAo9606 rigid:QGPE2/NeTz45rv5KYDV7s/8IwvQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H9Z2 uniprotkb:P39019 intact:EBI-2462365|ensembl:ENSP00000254231|ensembl:ENSP00000363314 intact:EBI-354451|ensembl:ENSP00000469228|ensembl:ENSP00000470004|ensembl:ENSP00000470972 psi-mi:ln28a_human(display_long)|uniprotkb:LIN28A(gene name)|psi-mi:LIN28A(display_short)|uniprotkb:CSDD1(gene name synonym)|uniprotkb:LIN28(gene name synonym)|uniprotkb:ZCCHC1(gene name synonym)|uniprotkb:Zinc finger CCHC domain-containing protein 1(gene name synonym) psi-mi:rs19_human(display_long)|uniprotkb:RPS19(gene name)|psi-mi:RPS19(display_short)|uniprotkb:Small ribosomal subunit protein eS19(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480521|imex:IM-26985-553 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540450.1|refseq:NP_078950.1|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0035198"(miRNA binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045686"(negative regulation of glial cell differentiation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071076"(RNA 3' uridylation)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:1901724"(positive regulation of cell proliferation involved in kidney development)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1905538"(polysome binding)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036875|mint:Q9H9Z2|rcsb pdb:2CQF|rcsb pdb:2LI8|rcsb pdb:5UDZ|reactome:R-HSA-452723|ensembl:ENSG00000131914(gene)|ensembl:ENST00000254231(transcript)|ensembl:ENST00000326279(transcript)|go:"GO:0000932"(P-body)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0031123"(RNA 3'-end processing) refseq:NP_001013.1|ensembl:ENSG00000105372(gene)|ensembl:ENST00000593863(transcript)|ensembl:ENST00000598742(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003723"(RNA binding)|ensembl:ENST00000600467(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0007000"(nucleolus organization)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0060265"(positive regulation of respiratory burst involved in inflammatory response)|go:"GO:0060266"(negative regulation of respiratory burst involved in inflammatory response)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001266(Ribosomal protein S19e)|interpro:IPR018277|interpro:IPR036388|interpro:IPR036390|mint:P39019|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001308412.1|refseq:NP_001308413.1 - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+74ZEfwOtT0fztME4RpHlyYIlww9606 rogid:3YqdJJJG+2nqoBf3PLu1fs7pVkY9606 rigid:QGPE2/NeTz45rv5KYDV7s/8IwvQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H9Z2 uniprotkb:P42766 intact:EBI-2462365|ensembl:ENSP00000254231|ensembl:ENSP00000363314 intact:EBI-356819|uniprotkb:Q4VBY5|uniprotkb:Q9BYF4|uniprotkb:Q5JTN5|uniprotkb:Q6IBC7|uniprotkb:Q96QJ7|uniprotkb:A8K4V7|ensembl:ENSP00000259469 psi-mi:ln28a_human(display_long)|uniprotkb:LIN28A(gene name)|psi-mi:LIN28A(display_short)|uniprotkb:CSDD1(gene name synonym)|uniprotkb:LIN28(gene name synonym)|uniprotkb:ZCCHC1(gene name synonym)|uniprotkb:Zinc finger CCHC domain-containing protein 1(gene name synonym) psi-mi:rl35_human(display_long)|uniprotkb:RPL35(gene name)|psi-mi:RPL35(display_short)|uniprotkb:Large ribosomal subunit protein uL29(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480521|imex:IM-26985-553 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540450.1|refseq:NP_078950.1|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0035198"(miRNA binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045686"(negative regulation of glial cell differentiation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071076"(RNA 3' uridylation)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:1901724"(positive regulation of cell proliferation involved in kidney development)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1905538"(polysome binding)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036875|mint:Q9H9Z2|rcsb pdb:2CQF|rcsb pdb:2LI8|rcsb pdb:5UDZ|reactome:R-HSA-452723|ensembl:ENSG00000131914(gene)|ensembl:ENST00000254231(transcript)|ensembl:ENST00000326279(transcript)|go:"GO:0000932"(P-body)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0031123"(RNA 3'-end processing) refseq:NP_009140.1|ensembl:ENSG00000136942(gene)|ensembl:ENST00000348462(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|interpro:IPR001854(Ribosomal protein L29)|interpro:IPR018254|interpro:IPR036049|mint:P42766|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+74ZEfwOtT0fztME4RpHlyYIlww9606 rogid:jhzt7gCff2vdUb1Ff/VTBF698Pg9606 rigid:QGPE2/NeTz45rv5KYDV7s/8IwvQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H9Z2 uniprotkb:Q9BUE0 intact:EBI-2462365|ensembl:ENSP00000254231|ensembl:ENSP00000363314 intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184 psi-mi:ln28a_human(display_long)|uniprotkb:LIN28A(gene name)|psi-mi:LIN28A(display_short)|uniprotkb:CSDD1(gene name synonym)|uniprotkb:LIN28(gene name synonym)|uniprotkb:ZCCHC1(gene name synonym)|uniprotkb:Zinc finger CCHC domain-containing protein 1(gene name synonym) psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480521|imex:IM-26985-553 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540450.1|refseq:NP_078950.1|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0035198"(miRNA binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045686"(negative regulation of glial cell differentiation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071076"(RNA 3' uridylation)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:1901724"(positive regulation of cell proliferation involved in kidney development)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1905538"(polysome binding)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036875|mint:Q9H9Z2|rcsb pdb:2CQF|rcsb pdb:2LI8|rcsb pdb:5UDZ|reactome:R-HSA-452723|ensembl:ENSG00000131914(gene)|ensembl:ENST00000254231(transcript)|ensembl:ENST00000326279(transcript)|go:"GO:0000932"(P-body)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0031123"(RNA 3'-end processing) refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 - - comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+74ZEfwOtT0fztME4RpHlyYIlww9606 rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606 rigid:QGPE2/NeTz45rv5KYDV7s/8IwvQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H9Z2 uniprotkb:Q13310 intact:EBI-2462365|ensembl:ENSP00000254231|ensembl:ENSP00000363314 intact:EBI-372844|uniprotkb:Q6P0N3|uniprotkb:B1ANQ8|ensembl:ENSP00000361948|intact:EBI-877641|uniprotkb:Q4VC03 psi-mi:ln28a_human(display_long)|uniprotkb:LIN28A(gene name)|psi-mi:LIN28A(display_short)|uniprotkb:CSDD1(gene name synonym)|uniprotkb:LIN28(gene name synonym)|uniprotkb:ZCCHC1(gene name synonym)|uniprotkb:Zinc finger CCHC domain-containing protein 1(gene name synonym) psi-mi:pabp4_human(display_long)|uniprotkb:PABPC4(gene name)|psi-mi:PABPC4(display_short)|uniprotkb:APP1(gene name synonym)|uniprotkb:PABP4(gene name synonym)|uniprotkb:"Inducible poly(A)-binding protein"(gene name synonym)|uniprotkb:Activated-platelet protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480521|imex:IM-26985-553 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540450.1|refseq:NP_078950.1|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0035198"(miRNA binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045686"(negative regulation of glial cell differentiation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071076"(RNA 3' uridylation)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:1901724"(positive regulation of cell proliferation involved in kidney development)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1905538"(polysome binding)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036875|mint:Q9H9Z2|rcsb pdb:2CQF|rcsb pdb:2LI8|rcsb pdb:5UDZ|reactome:R-HSA-452723|ensembl:ENSG00000131914(gene)|ensembl:ENST00000254231(transcript)|ensembl:ENST00000326279(transcript)|go:"GO:0000932"(P-body)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0031123"(RNA 3'-end processing) refseq:NP_001129126.1|refseq:NP_003810.1|ensembl:ENSG00000090621(gene)|ensembl:ENST00000372857(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006412"(translation)|go:"GO:0007596"(blood coagulation)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0061515"(myeloid cell development)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:Q13310|refseq:NP_001129125.1 - - comment:"author score: 29" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+74ZEfwOtT0fztME4RpHlyYIlww9606 rogid:u1qCM3o5X7jLIa1vyqFCIH7v01w9606 rigid:QGPE2/NeTz45rv5KYDV7s/8IwvQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H9Z2 uniprotkb:P11940 intact:EBI-2462365|ensembl:ENSP00000254231|ensembl:ENSP00000363314 intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004 psi-mi:ln28a_human(display_long)|uniprotkb:LIN28A(gene name)|psi-mi:LIN28A(display_short)|uniprotkb:CSDD1(gene name synonym)|uniprotkb:LIN28(gene name synonym)|uniprotkb:ZCCHC1(gene name synonym)|uniprotkb:Zinc finger CCHC domain-containing protein 1(gene name synonym) psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480521|imex:IM-26985-553 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540450.1|refseq:NP_078950.1|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0035198"(miRNA binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045686"(negative regulation of glial cell differentiation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071076"(RNA 3' uridylation)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:1901724"(positive regulation of cell proliferation involved in kidney development)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1905538"(polysome binding)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036875|mint:Q9H9Z2|rcsb pdb:2CQF|rcsb pdb:2LI8|rcsb pdb:5UDZ|reactome:R-HSA-452723|ensembl:ENSG00000131914(gene)|ensembl:ENST00000254231(transcript)|ensembl:ENST00000326279(transcript)|go:"GO:0000932"(P-body)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0031123"(RNA 3'-end processing) interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N - - comment:"author score: 35" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+74ZEfwOtT0fztME4RpHlyYIlww9606 rogid:XudTSPq2h9ckKAc48X88RVafPRU9606 rigid:QGPE2/NeTz45rv5KYDV7s/8IwvQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H9Z2 uniprotkb:P18077 intact:EBI-2462365|ensembl:ENSP00000254231|ensembl:ENSP00000363314 intact:EBI-353383|uniprotkb:Q08ES9|uniprotkb:Q9BVN7|ensembl:ENSP00000393393|ensembl:ENSP00000495672 psi-mi:ln28a_human(display_long)|uniprotkb:LIN28A(gene name)|psi-mi:LIN28A(display_short)|uniprotkb:CSDD1(gene name synonym)|uniprotkb:LIN28(gene name synonym)|uniprotkb:ZCCHC1(gene name synonym)|uniprotkb:Zinc finger CCHC domain-containing protein 1(gene name synonym) psi-mi:rl35a_human(display_long)|uniprotkb:RPL35A(gene name)|psi-mi:RPL35A(display_short)|uniprotkb:Cell growth-inhibiting gene 33 protein(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL33(gene name synonym)|uniprotkb:GIG33(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480521|imex:IM-26985-553 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540450.1|refseq:NP_078950.1|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0035198"(miRNA binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045686"(negative regulation of glial cell differentiation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071076"(RNA 3' uridylation)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:1901724"(positive regulation of cell proliferation involved in kidney development)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1905538"(polysome binding)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001878(Zinc finger, CCHC-type)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR036875|mint:Q9H9Z2|rcsb pdb:2CQF|rcsb pdb:2LI8|rcsb pdb:5UDZ|reactome:R-HSA-452723|ensembl:ENSG00000131914(gene)|ensembl:ENST00000254231(transcript)|ensembl:ENST00000326279(transcript)|go:"GO:0000932"(P-body)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031054"(pre-miRNA processing)|go:"GO:0031123"(RNA 3'-end processing) refseq:NP_000987.2|refseq:NP_001303240.1|ensembl:ENST00000647248(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001780(Ribosomal protein L35Ae)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR018266|interpro:IPR038661|mint:P18077|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|ensembl:ENSG00000182899(gene)|ensembl:ENST00000448864(transcript)|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - comment:"author score: 37" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+74ZEfwOtT0fztME4RpHlyYIlww9606 rogid:fnUlL17LsiOp3lSkKNsoYO74IQQ9606 rigid:QGPE2/NeTz45rv5KYDV7s/8IwvQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N3X6 uniprotkb:P12532 intact:EBI-7138654|ensembl:ENSP00000371661|uniprotkb:Q96NK1|intact:MINT-8247449 intact:EBI-1050662|uniprotkb:Q0VAM3|uniprotkb:Q32NF6|uniprotkb:Q53FC4|uniprotkb:B4DIT8|uniprotkb:B7ZA09|ensembl:ENSP00000300283|ensembl:ENSP00000406577|ensembl:ENSP00000413165|ensembl:ENSP00000413255 psi-mi:lcorl_human(display_long)|uniprotkb:LCORL(gene name)|psi-mi:LCORL(display_short) psi-mi:kcru_human(display_long)|uniprotkb:Ubiquitous mitochondrial creatine kinase(gene name synonym)|uniprotkb:Acidic-type mitochondrial creatine kinase(gene name synonym)|uniprotkb:CKMT1A(gene name)|psi-mi:CKMT1A(display_short)|uniprotkb:CKMT(gene name synonym)|uniprotkb:CKMT1B(gene name)|psi-mi:CKMT1B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480503|imex:IM-26985-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000178177(gene)|ensembl:ENST00000382226(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|mint:Q8N3X6|refseq:NP_001159611.1|refseq:NP_710153.2 refseq:NP_001015001.1|refseq:NP_066270.1|refseq:NP_001308855.1|refseq:NP_001308856.1|refseq:NP_001308857.1|refseq:XP_016877858.1|refseq:XP_016877859.1|refseq:XP_011519496.1|refseq:XP_011519497.1|refseq:XP_011519498.1|refseq:XP_011519499.1|ensembl:ENSG00000223572(gene)|ensembl:ENSG00000237289(gene)|ensembl:ENST00000300283(transcript)|ensembl:ENST00000413453(transcript)|ensembl:ENST00000434505(transcript)|ensembl:ENST00000441322(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0046314"(phosphocreatine biosynthetic process)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:P12532|rcsb pdb:1QK1|reactome:R-HSA-71288 - comment:mint|comment:homomint comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:SdBCrM1WJt4MBqkxpIqhIbfWHjM9606 rogid:2ZgqE1XmbPXtjVY6lIdy+e0bSdU9606 rigid:L+hRUNQdxGCelV3DIhMNJ4bCWTc false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N3X6 uniprotkb:P56545 intact:EBI-7138654|ensembl:ENSP00000371661|uniprotkb:Q96NK1|intact:MINT-8247449 intact:EBI-741533|uniprotkb:O43449|uniprotkb:Q5SQP7|uniprotkb:Q69YI3|uniprotkb:Q86SV0|uniprotkb:Q9H2T8|uniprotkb:A8K2X5|ensembl:ENSP00000338615|ensembl:ENSP00000410474|ensembl:ENSP00000434630|ensembl:ENSP00000436285|uniprotkb:D3DRF5|uniprotkb:Q8IY44|intact:EBI-11742664 psi-mi:lcorl_human(display_long)|uniprotkb:LCORL(gene name)|psi-mi:LCORL(display_short) psi-mi:ctbp2_human(display_long)|uniprotkb:CTBP2(gene name)|psi-mi:CTBP2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480503|imex:IM-26985-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000178177(gene)|ensembl:ENST00000382226(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|mint:Q8N3X6|refseq:NP_001159611.1|refseq:NP_710153.2 refseq:NP_001077383.1|refseq:NP_001320.1|refseq:NP_073713.2|refseq:NP_001307943.1|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098882"(structural constituent of presynaptic active zone)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:P56545|rcsb pdb:2OME|rcsb pdb:4LCJ|rcsb pdb:6WKW|reactome:R-HSA-4641265|reactome:R-HSA-5339700|reactome:R-HSA-9662360|go:"GO:0048386"(positive regulation of retinoic acid receptor signaling pathway)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0098684"(photoreceptor ribbon synapse)|ensembl:ENSG00000175029(gene)|ensembl:ENST00000337195(transcript)|ensembl:ENST00000411419(transcript)|ensembl:ENST00000494626(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|ensembl:ENST00000531469(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019079"(viral genome replication)|go:"GO:0019901"(protein kinase binding)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|refseq:XP_011537653.1|refseq:XP_011537655.1|refseq:XP_011537656.1|refseq:XP_011537657.1|refseq:NP_001307941.1|refseq:NP_001307942.1|refseq:XP_005269618.1|refseq:XP_005269621.1|refseq:XP_005269624.1|refseq:XP_005269625.1|refseq:XP_005269626.1|refseq:XP_005269628.1|refseq:XP_005269629.1|refseq:NP_001277143.1|refseq:NP_001277144.1|refseq:XP_006717705.1|refseq:XP_016871245.1|refseq:XP_016871246.1|dip:DIP-42104N|refseq:XP_011537651.1 - comment:mint|comment:homomint comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:SdBCrM1WJt4MBqkxpIqhIbfWHjM9606 rogid:6sKiqjMRW/ViEvTbQJoaUjgvZtc9606 rigid:L+hRUNQdxGCelV3DIhMNJ4bCWTc false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N3X6 uniprotkb:Q13363 intact:EBI-7138654|ensembl:ENSP00000371661|uniprotkb:Q96NK1|intact:MINT-8247449 intact:EBI-908846|uniprotkb:Q4W5N3|uniprotkb:Q7Z2Q5|ensembl:ENSP00000290921 psi-mi:lcorl_human(display_long)|uniprotkb:LCORL(gene name)|psi-mi:LCORL(display_short) psi-mi:ctbp1_human(display_long)|uniprotkb:CTBP1(gene name)|psi-mi:CTBP1(display_short)|uniprotkb:CTBP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480503|imex:IM-26985-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000178177(gene)|ensembl:ENST00000382226(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|mint:Q8N3X6|refseq:NP_001159611.1|refseq:NP_710153.2 refseq:NP_001012632.1|refseq:NP_001319.1|refseq:XP_016863253.1|refseq:XP_016863254.1|refseq:XP_016863255.1|refseq:XP_016863256.1|dip:DIP-24245N|ensembl:ENSG00000159692(gene)|ensembl:ENST00000290921(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019079"(viral genome replication)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0035067"(negative regulation of histone acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051287"(NAD binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090241"(negative regulation of histone H4 acetylation)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|interpro:IPR043322|mint:Q13363|rcsb pdb:1MX3|rcsb pdb:4LCE|rcsb pdb:4U6Q|rcsb pdb:4U6S|rcsb pdb:6CDF|rcsb pdb:6CDR|rcsb pdb:6V89|rcsb pdb:6V8A|rcsb pdb:7KWM|reactome:R-HSA-3769402|reactome:R-HSA-3899300|reactome:R-HSA-4641265|reactome:R-HSA-5339700 - comment:mint|comment:homomint comment:"author score: 71" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:SdBCrM1WJt4MBqkxpIqhIbfWHjM9606 rogid:hhYGrtcr0oAQW5x5LfNmxfuRNj49606 rigid:L+hRUNQdxGCelV3DIhMNJ4bCWTc false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N3X6 uniprotkb:Q14839 intact:EBI-7138654|ensembl:ENSP00000371661|uniprotkb:Q96NK1|intact:MINT-8247449 intact:EBI-372916|uniprotkb:Q8IXZ5|intact:EBI-28978241|ensembl:ENSP00000440542 psi-mi:lcorl_human(display_long)|uniprotkb:LCORL(gene name)|psi-mi:LCORL(display_short) psi-mi:chd4_human(display_long)|uniprotkb:CHD4(gene name)|psi-mi:CHD4(display_short)|uniprotkb:ATP-dependent helicase CHD4(gene name synonym)|uniprotkb:Mi-2 autoantigen 218 kDa protein(gene name synonym)|uniprotkb:Mi2-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480503|imex:IM-26985-33 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000178177(gene)|ensembl:ENST00000382226(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|mint:Q8N3X6|refseq:NP_001159611.1|refseq:NP_710153.2 ensembl:ENSP00000440542|ensembl:ENST00000645095|ensembl:ENSP00000496634|refseq:NP_001264.2|refseq:XP_006719021.1|refseq:NP_001284482.1|ensembl:ENSG00000111642(gene)|ensembl:ENST00000544040(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070615"|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:Q14839|rcsb pdb:1MM2|rcsb pdb:1MM3|rcsb pdb:2EE1|rcsb pdb:2L5U|rcsb pdb:2L75|rcsb pdb:2N5N|rcsb pdb:4O9I|rcsb pdb:6BGG|rcsb pdb:6Q3M|rcsb pdb:6RYR|rcsb pdb:6RYU|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9031628|reactome:R-HSA-9679191|dip:DIP-31183N - comment:mint|comment:homomint comment:"author score: 129" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:SdBCrM1WJt4MBqkxpIqhIbfWHjM9606 rogid:E9eHT/41SIFRiz54J81hvPQeHIE9606 rigid:L+hRUNQdxGCelV3DIhMNJ4bCWTc false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JM7 uniprotkb:Q9GZS3 intact:EBI-2686809|uniprotkb:Q4VXE1|uniprotkb:Q6P9B5|uniprotkb:Q5VUM9|ensembl:ENSP00000354526|ensembl:ENSP00000357118 intact:EBI-358545|uniprotkb:D3DW84|uniprotkb:Q6IA22|uniprotkb:Q7Z4X4|ensembl:ENSP00000267973|ensembl:ENSP00000453801 psi-mi:lmbl3_human(display_long)|uniprotkb:KIAA1798(gene name synonym)|uniprotkb:MBT1(gene name synonym)|uniprotkb:MBT-1(gene name synonym)|uniprotkb:L3MBTL3(gene name)|psi-mi:L3MBTL3(display_short) psi-mi:wdr61_human(display_long)|uniprotkb:WDR61(gene name)|psi-mi:WDR61(display_short)|uniprotkb:Meiotic recombination REC14 protein homolog(gene name synonym)|uniprotkb:SKI8 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480452|imex:IM-26985-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011534481.1|refseq:XP_011534482.1|refseq:XP_011534483.1|refseq:XP_011534485.1|refseq:XP_011534486.1|refseq:NP_001007103.1|refseq:NP_115814.1|refseq:NP_001333480.1|refseq:NP_001333479.1|refseq:XP_005267218.1|refseq:XP_006715641.1|ensembl:ENSG00000198945(gene)|ensembl:ENST00000361794(transcript)|ensembl:ENST00000368136(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q96JM7|rcsb pdb:1WJQ|rcsb pdb:1WJS|rcsb pdb:3UT1|rcsb pdb:4FL6|rcsb pdb:4L59|go:"GO:0042802"(identical protein binding)|dip:DIP-42798N refseq:NP_079510.1|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9GZS3|rcsb pdb:3OW8|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-429958|reactome:R-HSA-674695|reactome:R-HSA-75955|ensembl:ENSG00000140395(gene)|ensembl:ENST00000267973(transcript)|ensembl:ENST00000558311(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0055087"(Ski complex)|reactome:R-HSA-8866654|refseq:XP_011520396.1|refseq:NP_001290176.1|refseq:NP_001290177.1|dip:DIP-36672N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FYLlz+1Skg07Aw8gqXDVDFevaEg9606 rogid:yVcjv2BXXr3VFSR7OcJ/1u9L6gw9606 rigid:x2k8vYPEQTG5ULX/tLyc8Q8YKgU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JM7 uniprotkb:Q8NA19 intact:EBI-2686809|uniprotkb:Q4VXE1|uniprotkb:Q6P9B5|uniprotkb:Q5VUM9|ensembl:ENSP00000354526|ensembl:ENSP00000357118 intact:EBI-8833581|uniprotkb:A8MTL8|uniprotkb:Q8IXS3|ensembl:ENSP00000382976 psi-mi:lmbl3_human(display_long)|uniprotkb:KIAA1798(gene name synonym)|uniprotkb:MBT1(gene name synonym)|uniprotkb:MBT-1(gene name synonym)|uniprotkb:L3MBTL3(gene name)|psi-mi:L3MBTL3(display_short) psi-mi:lmbl4_human(display_long)|uniprotkb:L3MBTL4(gene name)|psi-mi:L3MBTL4(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480452|imex:IM-26985-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011534481.1|refseq:XP_011534482.1|refseq:XP_011534483.1|refseq:XP_011534485.1|refseq:XP_011534486.1|refseq:NP_001007103.1|refseq:NP_115814.1|refseq:NP_001333480.1|refseq:NP_001333479.1|refseq:XP_005267218.1|refseq:XP_006715641.1|ensembl:ENSG00000198945(gene)|ensembl:ENST00000361794(transcript)|ensembl:ENST00000368136(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q96JM7|rcsb pdb:1WJQ|rcsb pdb:1WJS|rcsb pdb:3UT1|rcsb pdb:4FL6|rcsb pdb:4L59|go:"GO:0042802"(identical protein binding)|dip:DIP-42798N refseq:XP_011524063.1|refseq:NP_775735.2|ensembl:ENSG00000154655(gene)|ensembl:ENST00000400105(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q8NA19|interpro:IPR002515(Zinc finger, C2HC-type) - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FYLlz+1Skg07Aw8gqXDVDFevaEg9606 rogid:3aoPBOJi3Hx/m4yM6uJ6h73p5949606 rigid:x2k8vYPEQTG5ULX/tLyc8Q8YKgU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JM7 uniprotkb:Q5VXD3 intact:EBI-2686809|uniprotkb:Q4VXE1|uniprotkb:Q6P9B5|uniprotkb:Q5VUM9|ensembl:ENSP00000354526|ensembl:ENSP00000357118 intact:EBI-8833527|uniprotkb:Q5VXD4|uniprotkb:Q53AI4|uniprotkb:Q5VXD2|uniprotkb:D3DT11|uniprotkb:B3KPW8|ensembl:ENSP00000359705 psi-mi:lmbl3_human(display_long)|uniprotkb:KIAA1798(gene name synonym)|uniprotkb:MBT1(gene name synonym)|uniprotkb:MBT-1(gene name synonym)|uniprotkb:L3MBTL3(gene name)|psi-mi:L3MBTL3(display_short) psi-mi:sam13_human(display_long)|uniprotkb:HSD-42(orf name)|uniprotkb:HSD42(orf name)|uniprotkb:SAMD13(gene name)|psi-mi:SAMD13(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480452|imex:IM-26985-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011534481.1|refseq:XP_011534482.1|refseq:XP_011534483.1|refseq:XP_011534485.1|refseq:XP_011534486.1|refseq:NP_001007103.1|refseq:NP_115814.1|refseq:NP_001333480.1|refseq:NP_001333479.1|refseq:XP_005267218.1|refseq:XP_006715641.1|ensembl:ENSG00000198945(gene)|ensembl:ENST00000361794(transcript)|ensembl:ENST00000368136(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q96JM7|rcsb pdb:1WJQ|rcsb pdb:1WJS|rcsb pdb:3UT1|rcsb pdb:4FL6|rcsb pdb:4L59|go:"GO:0042802"(identical protein binding)|dip:DIP-42798N refseq:XP_016855866.1|refseq:NP_001010971.1|refseq:NP_001128135.1|refseq:NP_001128136.1|ensembl:ENSG00000203943(gene)|ensembl:ENST00000370671(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q5VXD3 - - comment:"author score: 54" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FYLlz+1Skg07Aw8gqXDVDFevaEg9606 rogid:ssoQPKJU+FtnYlYhHX3S4GO/klU9606 rigid:x2k8vYPEQTG5ULX/tLyc8Q8YKgU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JM7 uniprotkb:Q9UHJ3 intact:EBI-2686809|uniprotkb:Q4VXE1|uniprotkb:Q6P9B5|uniprotkb:Q5VUM9|ensembl:ENSP00000354526|ensembl:ENSP00000357118 intact:EBI-747398|uniprotkb:Q96C73|uniprotkb:Q9Y4Q9|uniprotkb:Q402F7|ensembl:ENSP00000378235 psi-mi:lmbl3_human(display_long)|uniprotkb:KIAA1798(gene name synonym)|uniprotkb:MBT1(gene name synonym)|uniprotkb:MBT-1(gene name synonym)|uniprotkb:L3MBTL3(gene name)|psi-mi:L3MBTL3(display_short) psi-mi:smbt1_human(display_long)|uniprotkb:Renal ubiquitous protein 1(gene name synonym)|uniprotkb:SFMBT1(gene name)|psi-mi:SFMBT1(display_short)|uniprotkb:RU1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480452|imex:IM-26985-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011534481.1|refseq:XP_011534482.1|refseq:XP_011534483.1|refseq:XP_011534485.1|refseq:XP_011534486.1|refseq:NP_001007103.1|refseq:NP_115814.1|refseq:NP_001333480.1|refseq:NP_001333479.1|refseq:XP_005267218.1|refseq:XP_006715641.1|ensembl:ENSG00000198945(gene)|ensembl:ENST00000361794(transcript)|ensembl:ENST00000368136(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q96JM7|rcsb pdb:1WJQ|rcsb pdb:1WJS|rcsb pdb:3UT1|rcsb pdb:4FL6|rcsb pdb:4L59|go:"GO:0042802"(identical protein binding)|dip:DIP-42798N refseq:XP_006713266.1|refseq:XP_006713267.1|refseq:NP_057413.2|refseq:XP_011532126.1|refseq:XP_011532127.1|refseq:XP_005265278.1|ensembl:ENSG00000163935(gene)|ensembl:ENST00000394752(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048635"(negative regulation of muscle organ development)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR037604|interpro:IPR038348|mint:Q9UHJ3 - - comment:"author score: 70" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FYLlz+1Skg07Aw8gqXDVDFevaEg9606 rogid:vh/dDMpcLQEo57Wcjnggufh6HRk9606 rigid:x2k8vYPEQTG5ULX/tLyc8Q8YKgU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96JM7 uniprotkb:Q6SPF0 intact:EBI-2686809|uniprotkb:Q4VXE1|uniprotkb:Q6P9B5|uniprotkb:Q5VUM9|ensembl:ENSP00000354526|ensembl:ENSP00000357118 intact:EBI-8833536|uniprotkb:Q96IM4|uniprotkb:Q6PIS7|uniprotkb:Q6P0R3 psi-mi:lmbl3_human(display_long)|uniprotkb:KIAA1798(gene name synonym)|uniprotkb:MBT1(gene name synonym)|uniprotkb:MBT-1(gene name synonym)|uniprotkb:L3MBTL3(gene name)|psi-mi:L3MBTL3(display_short) psi-mi:samd1_human(display_long)|uniprotkb:SAMD1(gene name)|psi-mi:SAMD1(display_short)|uniprotkb:Atherin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480452|imex:IM-26985-29 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011534481.1|refseq:XP_011534482.1|refseq:XP_011534483.1|refseq:XP_011534485.1|refseq:XP_011534486.1|refseq:NP_001007103.1|refseq:NP_115814.1|refseq:NP_001333480.1|refseq:NP_001333479.1|refseq:XP_005267218.1|refseq:XP_006715641.1|ensembl:ENSG00000198945(gene)|ensembl:ENST00000361794(transcript)|ensembl:ENST00000368136(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030851"(granulocyte differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0043249"(erythrocyte maturation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q96JM7|rcsb pdb:1WJQ|rcsb pdb:1WJS|rcsb pdb:3UT1|rcsb pdb:4FL6|rcsb pdb:4L59|go:"GO:0042802"(identical protein binding)|dip:DIP-42798N mint:Q6SPF0|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_612361.1|go:"GO:0005737"(cytoplasm)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|rcsb pdb:6LUI|rcsb pdb:6LUJ|rcsb pdb:6LUK|go:"GO:0003682"(chromatin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus) - - comment:"author score: 128" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FYLlz+1Skg07Aw8gqXDVDFevaEg9606 rogid:Cav/ZfHiZJ1xCBI6jAYrzv+CmZ49606 rigid:x2k8vYPEQTG5ULX/tLyc8Q8YKgU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y383 uniprotkb:Q9UKV3 intact:EBI-352851|ensembl:ENSP00000347005|uniprotkb:Q8IUP9|uniprotkb:Q9NVL3|uniprotkb:Q9NVN7|uniprotkb:Q9UQN1|uniprotkb:B7Z500 intact:EBI-396258|uniprotkb:O75158|uniprotkb:Q9UG91|uniprotkb:Q9UKV1|uniprotkb:Q9UKV2|uniprotkb:D3DS45|uniprotkb:B2RTT4|ensembl:ENSP00000262710 psi-mi:lc7l2_human(display_long)|uniprotkb:LUC7L2(gene name)|psi-mi:LUC7L2(display_short)|uniprotkb:CGI-59(orf name)|uniprotkb:CGI-74(orf name) psi-mi:acinu_human(display_long)|uniprotkb:ACIN1(gene name)|psi-mi:ACIN1(display_short)|uniprotkb:ACINUS(gene name synonym)|uniprotkb:KIAA0670(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480590|imex:IM-26985-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000146963(gene)|ensembl:ENST00000354926(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005685"(U1 snRNP)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR004882(LUC7 related)|mint:Q9Y383|refseq:NP_057103.2|refseq:NP_001231514.1|refseq:NP_001257572.1|dip:DIP-32513N refseq:NP_001158286.1|refseq:NP_001158287.1|refseq:NP_001158288.1|refseq:NP_001158289.1|refseq:NP_055792.1|refseq:XP_005267475.1|ensembl:ENSG00000100813(gene)|ensembl:ENST00000262710(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030263"(apoptotic chromosome condensation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0061574"(ASAP complex)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034257|interpro:IPR035979|interpro:IPR036361|mint:Q9UKV3|rcsb pdb:6G6S|reactome:R-HSA-111465|interpro:IPR032552|dip:DIP-32963N - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:WLp3u1YbXtdPGzIm6WxvAbrQKhM9606 rogid:dzHCIefdTYTGEk+qXNwlK2Phybw9606 rigid:eLOoZtNY1FlKVm/NFBcaPSXRrMo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y383 uniprotkb:O95232 intact:EBI-352851|ensembl:ENSP00000347005|uniprotkb:Q8IUP9|uniprotkb:Q9NVL3|uniprotkb:Q9NVN7|uniprotkb:Q9UQN1|uniprotkb:B7Z500 intact:EBI-395671|uniprotkb:Q6PHR9|uniprotkb:Q9NUY0|uniprotkb:Q9P2S7|uniprotkb:B3KN54|uniprotkb:D3DTY1|ensembl:ENSP00000240304|ensembl:ENSP00000425092 psi-mi:lc7l2_human(display_long)|uniprotkb:LUC7L2(gene name)|psi-mi:LUC7L2(display_short)|uniprotkb:CGI-59(orf name)|uniprotkb:CGI-74(orf name) psi-mi:lc7l3_human(display_long)|uniprotkb:LUC7L3(gene name)|psi-mi:LUC7L3(display_short)|uniprotkb:cAMP regulatory element-associated protein 1(gene name synonym)|uniprotkb:Luc7A(gene name synonym)|uniprotkb:Okadaic acid-inducible phosphoprotein OA48-18(gene name synonym)|uniprotkb:CREAP1(gene name synonym)|uniprotkb:O48(gene name synonym)|uniprotkb:CROP(gene name synonym)|uniprotkb:Cisplatin resistance-associated-overexpressed protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480590|imex:IM-26985-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000146963(gene)|ensembl:ENST00000354926(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005685"(U1 snRNP)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR004882(LUC7 related)|mint:Q9Y383|refseq:NP_057103.2|refseq:NP_001231514.1|refseq:NP_001257572.1|dip:DIP-32513N refseq:NP_006098.2|refseq:NP_057508.2|ensembl:ENSG00000108848(gene)|ensembl:ENST00000240304(transcript)|ensembl:ENST00000505658(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005685"(U1 snRNP)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR004882(LUC7 related)|mint:O95232 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:WLp3u1YbXtdPGzIm6WxvAbrQKhM9606 rogid:UywyrESxjWtcX7tXUEvhA6Dks709606 rigid:eLOoZtNY1FlKVm/NFBcaPSXRrMo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y383 uniprotkb:O95218 intact:EBI-352851|ensembl:ENSP00000347005|uniprotkb:Q8IUP9|uniprotkb:Q9NVL3|uniprotkb:Q9NVN7|uniprotkb:Q9UQN1|uniprotkb:B7Z500 intact:EBI-1051583|intact:EBI-1642120|intact:EBI-1163882|intact:EBI-1166395|uniprotkb:Q53GS3|uniprotkb:Q59F92|uniprotkb:Q5VV33|uniprotkb:Q8IXN6|uniprotkb:Q9UP63|uniprotkb:Q5VV34|uniprotkb:D3DQ75|ensembl:ENSP00000359958 psi-mi:lc7l2_human(display_long)|uniprotkb:LUC7L2(gene name)|psi-mi:LUC7L2(display_short)|uniprotkb:CGI-59(orf name)|uniprotkb:CGI-74(orf name) psi-mi:zrab2_human(display_long)|uniprotkb:ZRANB2(gene name)|psi-mi:ZRANB2(display_short)|uniprotkb:ZIS(gene name synonym)|uniprotkb:ZNF265(gene name synonym)|uniprotkb:Zinc finger protein 265(gene name synonym)|uniprotkb:Zinc finger, splicing(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480590|imex:IM-26985-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000146963(gene)|ensembl:ENST00000354926(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005685"(U1 snRNP)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR004882(LUC7 related)|mint:Q9Y383|refseq:NP_057103.2|refseq:NP_001231514.1|refseq:NP_001257572.1|dip:DIP-32513N refseq:NP_005446.2|refseq:NP_976225.1|ensembl:ENSG00000132485(gene)|ensembl:ENST00000370920(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR017337(Uncharacterised conserved protein UCP037956, zinc finger Ran-binding)|interpro:IPR036443|mint:O95218|rcsb pdb:1N0Z|rcsb pdb:2K1P|rcsb pdb:3G9Y - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:WLp3u1YbXtdPGzIm6WxvAbrQKhM9606 rogid:NSsZyRDwY5bF3I5OGvd1jGYTijY9606 rigid:eLOoZtNY1FlKVm/NFBcaPSXRrMo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y383 uniprotkb:Q9Y6A4 intact:EBI-352851|ensembl:ENSP00000347005|uniprotkb:Q8IUP9|uniprotkb:Q9NVL3|uniprotkb:Q9NVN7|uniprotkb:Q9UQN1|uniprotkb:B7Z500 intact:EBI-1046872|ensembl:ENSP00000262498 psi-mi:lc7l2_human(display_long)|uniprotkb:LUC7L2(gene name)|psi-mi:LUC7L2(display_short)|uniprotkb:CGI-59(orf name)|uniprotkb:CGI-74(orf name) psi-mi:cfa20_human(display_long)|uniprotkb:GTL3(gene name synonym)|uniprotkb:CFAP20(gene name)|psi-mi:CFAP20(display_short)|uniprotkb:BUG22(gene name synonym)|uniprotkb:Basal body up-regulated protein 22(gene name synonym)|uniprotkb:C16orf80(gene name synonym)|uniprotkb:Transcription factor IIB(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480590|imex:IM-26985-35 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000146963(gene)|ensembl:ENST00000354926(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005685"(U1 snRNP)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0071004"(U2-type prespliceosome)|interpro:IPR004882(LUC7 related)|mint:Q9Y383|refseq:NP_057103.2|refseq:NP_001231514.1|refseq:NP_001257572.1|dip:DIP-32513N ensembl:ENSG00000070761(gene)|ensembl:ENST00000262498(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0007275"(multicellular organism development)|go:"GO:0018095"(protein polyglutamylation)|go:"GO:0031514"(motile cilium)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|go:"GO:0060296"(regulation of cilium beat frequency involved in ciliary motility)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000147"(positive regulation of cell motility)|go:"GO:2000253"(positive regulation of feeding behavior)|interpro:IPR007714(Protein of unknown function DUF667)|interpro:IPR040441|mint:Q9Y6A4|refseq:NP_037374.1 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:WLp3u1YbXtdPGzIm6WxvAbrQKhM9606 rogid:S9Z+L4oH2cj0qCK00ZIAvreEqfU9606 rigid:eLOoZtNY1FlKVm/NFBcaPSXRrMo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61244 uniprotkb:Q7KZF4 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 intact:EBI-1044112|uniprotkb:Q13122|ensembl:ENSP00000346762|uniprotkb:Q96AG0 psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:snd1_human(display_long)|uniprotkb:100 kDa coactivator(gene name synonym)|uniprotkb:EBNA2 coactivator p100(gene name synonym)|uniprotkb:Tudor domain-containing protein 11(gene name synonym)|uniprotkb:SND1(gene name)|psi-mi:SND1(display_short)|uniprotkb:p100 co-activator(gene name synonym)|uniprotkb:TDRD11(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480608|imex:IM-26985-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750 refseq:NP_055205.2|ensembl:ENSG00000197157(gene)|ensembl:ENST00000354725(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0042470"(melanosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097433"(dense body)|go:"GO:1905172"(RISC complex binding)|interpro:IPR002071(Thermonuclease active site)|interpro:IPR002999(Tudor)|interpro:IPR016071("Staphylococcal nuclease (SNase-like), OB-fold")|interpro:IPR016685(RNA-induced silencing complex, nuclease component Tudor-SN)|interpro:IPR035437|mint:Q7KZF4|rcsb pdb:2E6N|rcsb pdb:2HQE|rcsb pdb:2HQX|rcsb pdb:2O4X|rcsb pdb:3BDL|rcsb pdb:3OMC|rcsb pdb:3OMG|rcsb pdb:4QMG|rcsb pdb:5M9O|reactome:R-HSA-6802952|dip:DIP-29613N - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:I5d1d/zT353OsLios95yEITNoWU9606 rogid:I9JNlRfASs5dwk0JZQ+F+GsW94g9606 rigid:NB/2TbYQCcvFln/Z9i2TFR4m/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61244 uniprotkb:Q9HC38 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 intact:EBI-1049764|uniprotkb:Q96B89|uniprotkb:Q9H3J8|uniprotkb:Q9HC37|uniprotkb:Q9NVN1|uniprotkb:D3DTG9|uniprotkb:D3DTH1|ensembl:ENSP00000301328 psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:glod4_human(display_long)|uniprotkb:GLOD4(gene name)|psi-mi:GLOD4(display_short)|uniprotkb:C17orf25(gene name synonym)|uniprotkb:CGI-150(orf name)|uniprotkb:My027(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480608|imex:IM-26985-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750 refseq:NP_057164.3|ensembl:ENSG00000167699(gene)|ensembl:ENST00000301328(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR029068|interpro:IPR037523|interpro:IPR043193|mint:Q9HC38|rcsb pdb:3ZI1|interpro:IPR043194 - - comment:"author score: 33" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:I5d1d/zT353OsLios95yEITNoWU9606 rogid:0Xu9EPSkmX9t8j0yLaCyBLhKcUs9606 rigid:NB/2TbYQCcvFln/Z9i2TFR4m/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61244 uniprotkb:Q8IWI9 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 intact:EBI-2815196|uniprotkb:E7ENI0|uniprotkb:F5H7K2|uniprotkb:Q9H9N7|uniprotkb:Q9H8R3|uniprotkb:Q9Y4E9|uniprotkb:Q9UG69|intact:EBI-11143500|intact:EBI-10969960|ensembl:ENSP00000219905|uniprotkb:B9EGR5 psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:mgap_human(display_long)|uniprotkb:MGA(gene name)|psi-mi:MGA(display_short)|uniprotkb:KIAA0518(gene name synonym)|uniprotkb:MAD5(gene name synonym)|uniprotkb:MAX dimerization protein 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480608|imex:IM-26985-37 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750 refseq:NP_001074010.2|ensembl:ENSP00000219905|ensembl:ENST00000566586|ensembl:ENSP00000456141|ensembl:ENSG00000174197(gene)|ensembl:ENST00000219905(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR018186|interpro:IPR032060|interpro:IPR036638|interpro:IPR036960|interpro:IPR037935|mint:Q8IWI9|reactome:R-HSA-8953750|refseq:NP_001157745.1|dip:DIP-57615N - - comment:"author score: 34" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:I5d1d/zT353OsLios95yEITNoWU9606 rogid:P4lo9EteCvikQQk5kyVkcobitLU9606 rigid:NB/2TbYQCcvFln/Z9i2TFR4m/3k false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05BQ5 uniprotkb:Q9Y2S7 intact:EBI-5666902|uniprotkb:Q9NXU1|uniprotkb:Q6ZVU7|ensembl:ENSP00000403946|ensembl:ENSP00000468304 intact:EBI-713000|ensembl:ENSP00000475924|uniprotkb:Q96JE4|uniprotkb:B2R846 psi-mi:mbtd1_human(display_long)|uniprotkb:MBTD1(gene name)|psi-mi:MBTD1(display_short) psi-mi:pdip2_human(display_long)|uniprotkb:38 kDa DNA polymerase delta interaction protein(gene name synonym)|uniprotkb:POLDIP2(gene name)|psi-mi:POLDIP2(display_short)|uniprotkb:PDIP38(gene name synonym)|uniprotkb:POLD4(gene name synonym)|uniprotkb:HSPC017(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480632|imex:IM-26985-105 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011523238.1|refseq:NP_060113.2|ensembl:ENSG00000011258(gene)|ensembl:ENST00000415868(transcript)|ensembl:ENST00000586178(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048706"(embryonic skeletal system development)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038603|mint:Q05BQ5|rcsb pdb:3FEO|rcsb pdb:4C5I|rcsb pdb:6NFX ensembl:ENSG00000004142(gene)|ensembl:ENST00000540200(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0016242"(negative regulation of macroautophagy)|go:"GO:0030496"(midbody)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0070987"(error-free translesion synthesis)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1903490"(positive regulation of mitotic cytokinesis)|go:"GO:1904531"(positive regulation of actin filament binding)|go:"GO:1990874"(vascular associated smooth muscle cell proliferation)|go:"GO:2001108"(positive regulation of Rho guanyl-nucleotide exchange factor activity)|interpro:IPR007474(ApaG)|interpro:IPR011722(Hemimethylated DNA-binding region)|interpro:IPR036623|interpro:IPR036767|mint:Q9Y2S7|rcsb pdb:6Z9C|refseq:NP_056399.1|refseq:NP_001277074.1 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Osdh7GfOtCTGyigRfOAYp5sL84Y9606 rogid:eZmek2xqphKowjP6zwsH6ydfz3g9606 rigid:iKYpKXnOBH5zICeMLsxR8zlwTNI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q05BQ5 uniprotkb:Q13242 intact:EBI-5666902|uniprotkb:Q9NXU1|uniprotkb:Q6ZVU7|ensembl:ENSP00000403946|ensembl:ENSP00000468304 intact:EBI-2949710|ensembl:ENSP00000229390|uniprotkb:Q52LD1 psi-mi:mbtd1_human(display_long)|uniprotkb:MBTD1(gene name)|psi-mi:MBTD1(display_short) psi-mi:srsf9_human(display_long)|uniprotkb:SRSF9(gene name)|psi-mi:SRSF9(display_short)|uniprotkb:SFRS9(gene name synonym)|uniprotkb:SRP30C(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SRp30C(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480632|imex:IM-26985-105 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011523238.1|refseq:NP_060113.2|ensembl:ENSG00000011258(gene)|ensembl:ENST00000415868(transcript)|ensembl:ENST00000586178(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048706"(embryonic skeletal system development)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038603|mint:Q05BQ5|rcsb pdb:3FEO|rcsb pdb:4C5I|rcsb pdb:6NFX go:"GO:0006397"(mRNA processing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043279"(response to alkaloid)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|go:"GO:0006376"(mRNA splice site selection)|interpro:IPR034503|interpro:IPR034995|interpro:IPR035979|mint:Q13242|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|ensembl:ENSG00000111786(gene)|ensembl:ENST00000229390(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|refseq:NP_003760.1|dip:DIP-40741N - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Osdh7GfOtCTGyigRfOAYp5sL84Y9606 rogid:9x6TWFk1zN1YodjXBiwi/MtNJe49606 rigid:iKYpKXnOBH5zICeMLsxR8zlwTNI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P82663 uniprotkb:Q9UJA3 intact:EBI-1046734|uniprotkb:Q9H7P5|ensembl:ENSP00000253686|uniprotkb:B4DFJ5|uniprotkb:B4DQG6 intact:EBI-8756095|uniprotkb:B2RBG7|uniprotkb:D3DW08|uniprotkb:E7EQU7|uniprotkb:Q495R4|uniprotkb:Q495R6|uniprotkb:Q495R7|uniprotkb:Q86US4|uniprotkb:Q969I5|ensembl:ENSP00000368174|ensembl:ENSP00000478141 psi-mi:rt25_human(display_long)|uniprotkb:MRPS25(gene name)|psi-mi:MRPS25(display_short)|uniprotkb:RPMS25(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS25(gene name synonym) psi-mi:mcm8_human(display_long)|uniprotkb:MCM8(gene name)|psi-mi:MCM8(display_short)|uniprotkb:C20orf154(gene name synonym)|uniprotkb:Minichromosome maintenance 8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25480644|imex:IM-26985-107 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_071942.1|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000131368(gene)|ensembl:ENST00000253686(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005840"(ribosome)|interpro:IPR007741(Mitochondrial ribosome)|interpro:IPR036249|interpro:IPR040049|mint:P82663|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5 refseq:XP_016883594.1|refseq:NP_115874.3|refseq:NP_877954.1|refseq:NP_001268449.1|refseq:NP_001268450.1|refseq:NP_001268451.1|ensembl:ENST00000378896(transcript)|ensembl:ENST00000610722(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003682"(chromatin binding)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|ensembl:ENSG00000125885(gene)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0007292"(female gamete generation)|go:"GO:0019899"(enzyme binding)|go:"GO:0032406"(MutLbeta complex binding)|go:"GO:0032407"(MutSalpha complex binding)|go:"GO:0032408"(MutSbeta complex binding)|go:"GO:0036298"(recombinational interstrand cross-link repair)|go:"GO:0042555"(MCM complex)|go:"GO:0048232"(male gamete generation)|go:"GO:0050821"(protein stabilization)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0097362"(MCM8-MCM9 complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001208(MCM)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR027417|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:Q9UJA3|rcsb pdb:6L0O|rcsb pdb:7DP3|reactome:R-HSA-113507|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68689|reactome:R-HSA-68827|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962 - comment:"author score: 13" - figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:DQMtBaQJW2Ic025zsKJYfN4aj1I9606 rogid:po4hzJ/+5JWxog5BnKAfHYKmE7w9606 rigid:tX3/mwGfCNvhfUgUHJ5uVGE1XPI false - tandem tag:n-n - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q03112 uniprotkb:Q9Y6H1 intact:EBI-1384862|uniprotkb:Q16122|uniprotkb:Q99917|uniprotkb:C9JAK0|uniprotkb:Q5HYI1|uniprotkb:Q6MZS6|uniprotkb:Q8NEI5|uniprotkb:A1L4F3|uniprotkb:A8KA00|uniprotkb:B7Z8W7|uniprotkb:B7ZLQ3|uniprotkb:B7ZLQ4|uniprotkb:D3DNP7|ensembl:ENSP00000417899|intact:EBI-8475192|intact:MINT-8417693|uniprotkb:E7EQ57|uniprotkb:Q13465|uniprotkb:Q13466|uniprotkb:Q6FH90 intact:EBI-2321769|uniprotkb:Q498C3|uniprotkb:Q6NZ50|ensembl:ENSP00000378812 psi-mi:mecom_human(display_long)|uniprotkb:MECOM(gene name)|psi-mi:MECOM(display_short)|uniprotkb:EVI1(gene name synonym)|uniprotkb:Ecotropic virus integration site 1 protein homolog(gene name synonym)|uniprotkb:MDS1(gene name synonym)|uniprotkb:Myelodysplasia syndrome 1 protein(gene name synonym)|uniprotkb:Myelodysplasia syndrome-associated protein 1(gene name synonym)|uniprotkb:MDS1 and EVI1 complex locus protein(gene name synonym)|uniprotkb:PRDM3(gene name synonym) psi-mi:chch2_human(display_long)|uniprotkb:CHCHD2(gene name)|psi-mi:CHCHD2(display_short)|uniprotkb:C7orf17(gene name synonym)|uniprotkb:HCV NS2 trans-regulated protein(gene name synonym)|uniprotkb:Aging-associated gene 10 protein(gene name synonym)|uniprotkb:AAG10(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480653|imex:IM-26985-485 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001098547.3|refseq:NP_001098548.2|refseq:NP_001157471.1|refseq:NP_001157472.1|refseq:NP_001192123.1|refseq:NP_004982.2|refseq:NP_005232.2|ensembl:ENSG00000085276(gene)|ensembl:ENST00000494292(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0071425"(hematopoietic stem cell proliferation)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR044411|mint:Q03112|rcsb pdb:6BW3|reactome:R-HSA-3214841|reactome:R-HSA-8943724|interpro:IPR036236|refseq:XP_016861363.1|refseq:XP_016861364.1|refseq:XP_016861365.1|refseq:XP_005247278.1|refseq:XP_005247280.1|refseq:XP_005247272.1|dip:DIP-38639N|refseq:XP_005247276.1|refseq:XP_005247277.1 refseq:NP_057223.1|ensembl:ENSG00000106153(gene)|ensembl:ENST00000395422(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900037"(regulation of cellular response to hypoxia)|go:"GO:1905448"(positive regulation of mitochondrial ATP synthesis coupled electron transport)|interpro:IPR010625(CHCH)|mint:Q9Y6H1|reactome:R-HSA-1268020 - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MAlEIuVZS4+BNoy50jejv2O30WA9606 rogid:fdx3lE51+yZ1k3uwh8/LDKJC+CQ9606 rigid:x74y79rgJtPYuODkmSwjhxDlAmM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q03112 uniprotkb:Q92624 intact:EBI-1384862|uniprotkb:Q16122|uniprotkb:Q99917|uniprotkb:C9JAK0|uniprotkb:Q5HYI1|uniprotkb:Q6MZS6|uniprotkb:Q8NEI5|uniprotkb:A1L4F3|uniprotkb:A8KA00|uniprotkb:B7Z8W7|uniprotkb:B7ZLQ3|uniprotkb:B7ZLQ4|uniprotkb:D3DNP7|ensembl:ENSP00000417899|intact:EBI-8475192|intact:MINT-8417693|uniprotkb:E7EQ57|uniprotkb:Q13465|uniprotkb:Q13466|uniprotkb:Q6FH90 intact:EBI-743771|uniprotkb:O95095|uniprotkb:Q8WVC9|uniprotkb:A8K862|ensembl:ENSP00000083182 psi-mi:mecom_human(display_long)|uniprotkb:MECOM(gene name)|psi-mi:MECOM(display_short)|uniprotkb:EVI1(gene name synonym)|uniprotkb:Ecotropic virus integration site 1 protein homolog(gene name synonym)|uniprotkb:MDS1(gene name synonym)|uniprotkb:Myelodysplasia syndrome 1 protein(gene name synonym)|uniprotkb:Myelodysplasia syndrome-associated protein 1(gene name synonym)|uniprotkb:MDS1 and EVI1 complex locus protein(gene name synonym)|uniprotkb:PRDM3(gene name synonym) psi-mi:apbp2_human(display_long)|uniprotkb:Amyloid beta precursor protein-binding protein 2(gene name synonym)|uniprotkb:Protein interacting with APP tail 1(gene name synonym)|uniprotkb:APPBP2(gene name)|psi-mi:APPBP2(display_short)|uniprotkb:KIAA0228(gene name synonym)|uniprotkb:PAT1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480653|imex:IM-26985-485 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001098547.3|refseq:NP_001098548.2|refseq:NP_001157471.1|refseq:NP_001157472.1|refseq:NP_001192123.1|refseq:NP_004982.2|refseq:NP_005232.2|ensembl:ENSG00000085276(gene)|ensembl:ENST00000494292(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0071425"(hematopoietic stem cell proliferation)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR044411|mint:Q03112|rcsb pdb:6BW3|reactome:R-HSA-3214841|reactome:R-HSA-8943724|interpro:IPR036236|refseq:XP_016861363.1|refseq:XP_016861364.1|refseq:XP_016861365.1|refseq:XP_005247278.1|refseq:XP_005247280.1|refseq:XP_005247272.1|dip:DIP-38639N|refseq:XP_005247276.1|refseq:XP_005247277.1 refseq:NP_001269405.1|refseq:NP_006371.2|ensembl:ENSG00000062725(gene)|ensembl:ENST00000083182(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046907"(intracellular transport)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q92624|interpro:IPR042476 - - comment:"author score: 27" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MAlEIuVZS4+BNoy50jejv2O30WA9606 rogid:v3OsJTC6qSupyl7flB7A/tYhIDU9606 rigid:x74y79rgJtPYuODkmSwjhxDlAmM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q03112 uniprotkb:Q99417 intact:EBI-1384862|uniprotkb:Q16122|uniprotkb:Q99917|uniprotkb:C9JAK0|uniprotkb:Q5HYI1|uniprotkb:Q6MZS6|uniprotkb:Q8NEI5|uniprotkb:A1L4F3|uniprotkb:A8KA00|uniprotkb:B7Z8W7|uniprotkb:B7ZLQ3|uniprotkb:B7ZLQ4|uniprotkb:D3DNP7|ensembl:ENSP00000417899|intact:EBI-8475192|intact:MINT-8417693|uniprotkb:E7EQ57|uniprotkb:Q13465|uniprotkb:Q13466|uniprotkb:Q6FH90 intact:EBI-716185|intact:EBI-2559925|uniprotkb:Q5TA64|uniprotkb:Q96HE2|uniprotkb:B2R4N0|ensembl:ENSP00000380702 psi-mi:mecom_human(display_long)|uniprotkb:MECOM(gene name)|psi-mi:MECOM(display_short)|uniprotkb:EVI1(gene name synonym)|uniprotkb:Ecotropic virus integration site 1 protein homolog(gene name synonym)|uniprotkb:MDS1(gene name synonym)|uniprotkb:Myelodysplasia syndrome 1 protein(gene name synonym)|uniprotkb:Myelodysplasia syndrome-associated protein 1(gene name synonym)|uniprotkb:MDS1 and EVI1 complex locus protein(gene name synonym)|uniprotkb:PRDM3(gene name synonym) psi-mi:mycbp_human(display_long)|uniprotkb:Associate of Myc 1(gene name synonym)|uniprotkb:MYCBP(gene name)|psi-mi:MYCBP(display_short)|uniprotkb:AMY1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480653|imex:IM-26985-485 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001098547.3|refseq:NP_001098548.2|refseq:NP_001157471.1|refseq:NP_001157472.1|refseq:NP_001192123.1|refseq:NP_004982.2|refseq:NP_005232.2|ensembl:ENSG00000085276(gene)|ensembl:ENST00000494292(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0071425"(hematopoietic stem cell proliferation)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR044411|mint:Q03112|rcsb pdb:6BW3|reactome:R-HSA-3214841|reactome:R-HSA-8943724|interpro:IPR036236|refseq:XP_016861363.1|refseq:XP_016861364.1|refseq:XP_016861365.1|refseq:XP_005247278.1|refseq:XP_005247280.1|refseq:XP_005247272.1|dip:DIP-38639N|refseq:XP_005247276.1|refseq:XP_005247277.1 refseq:NP_036465.2|ensembl:ENSG00000214114(gene)|ensembl:ENST00000397572(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007283"(spermatogenesis)|interpro:IPR026060|mint:Q99417|rcsb pdb:2YY0 - - comment:"author score: 30" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MAlEIuVZS4+BNoy50jejv2O30WA9606 rogid:jIStn1A10DDkgTuwVeKpDPJ6tIs9606 rigid:x74y79rgJtPYuODkmSwjhxDlAmM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P51608 uniprotkb:O00629 intact:EBI-1189067|uniprotkb:O15233|uniprotkb:Q6QHH9|uniprotkb:Q7Z384|ensembl:ENSP00000301948 intact:EBI-396343|uniprotkb:O00190|intact:EBI-28976443|ensembl:ENSP00000334373|uniprotkb:A8K4S6|uniprotkb:D3DNM2 psi-mi:mecp2_human(display_long)|uniprotkb:MECP2(gene name)|psi-mi:MECP2(display_short) psi-mi:ima3_human(display_long)|uniprotkb:KPNA4(gene name)|psi-mi:KPNA4(display_short)|uniprotkb:QIP1(gene name synonym)|uniprotkb:Karyopherin subunit alpha-4(gene name synonym)|uniprotkb:Importin alpha Q1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480668|imex:IM-26985-181 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001104262.1|refseq:NP_004983.1|refseq:NP_001303266.1|ensembl:ENSG00000169057(gene)|ensembl:ENST00000303391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0001662"(behavioral fear response)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001964"(startle response)|go:"GO:0001976"(nervous system process involved in regulation of systemic arterial blood pressure)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006020"(inositol metabolic process)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006576"(cellular biogenic amine metabolic process)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007416"(synapse assembly)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0007616"(long-term memory)|go:"GO:0008104"(protein localization)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016358"(dendrite development)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016571"(histone methylation)|go:"GO:0016573"(histone acetylation)|go:"GO:0019230"(proprioception)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021591"(ventricular system development)|go:"GO:0032048"(cardiolipin metabolic process)|go:"GO:0035176"(social behavior)|go:"GO:0035197"(siRNA binding)|go:"GO:0042551"(neuron maturation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051151"(negative regulation of smooth muscle cell differentiation)|go:"GO:0051707"(response to other organism)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0098794"(postsynapse)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|go:"GO:1905643"(positive regulation of DNA methylation)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000820"(negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR017353(Methyl-CpG binding protein MeCP2)|mint:P51608|rcsb pdb:1QK9|rcsb pdb:3C2I|rcsb pdb:5BT2|rcsb pdb:6C1Y|rcsb pdb:6OGJ|rcsb pdb:6OGK|reactome:R-HSA-8986944|reactome:R-HSA-9022534|reactome:R-HSA-9022535|reactome:R-HSA-9022537|reactome:R-HSA-9022538|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9022702|reactome:R-HSA-9022707|reactome:R-HSA-9022927|dip:DIP-39983N refseq:NP_002259.1|ensembl:ENSG00000186432(gene)|ensembl:ENST00000334256(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O00629|rcsb pdb:4UAE|rcsb pdb:5TBK|rcsb pdb:5XZX|rcsb pdb:6BVV|rcsb pdb:6BVZ|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|rcsb pdb:6WX8|rcsb pdb:7JJL|reactome:R-HSA-1169408|reactome:R-HSA-168276|ensembl:ENSP00000334373|dip:DIP-32982N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:7c5ZZAZsqV7AciGN4hzFNWJLeUk9606 rogid:/cng/xZ42E2juzHNOpuQTP+amx89606 rigid:8qu/QD/5itLG+dPNu2Y1J+dhoXM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P51608 uniprotkb:O00505 intact:EBI-1189067|uniprotkb:O15233|uniprotkb:Q6QHH9|uniprotkb:Q7Z384|ensembl:ENSP00000301948 intact:EBI-358297|intact:EBI-28976892|ensembl:ENSP00000261667|uniprotkb:O00191|uniprotkb:O43195|uniprotkb:Q96AA7|uniprotkb:Q5JVM9|intact:EBI-742146|uniprotkb:Q8IYQ9 psi-mi:mecp2_human(display_long)|uniprotkb:MECP2(gene name)|psi-mi:MECP2(display_short) psi-mi:ima4_human(display_long)|uniprotkb:KPNA3(gene name)|psi-mi:KPNA3(display_short)|uniprotkb:QIP2(gene name synonym)|uniprotkb:Karyopherin subunit alpha-3(gene name synonym)|uniprotkb:SRP1-gamma(gene name synonym)|uniprotkb:Importin alpha Q2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480668|imex:IM-26985-181 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001104262.1|refseq:NP_004983.1|refseq:NP_001303266.1|ensembl:ENSG00000169057(gene)|ensembl:ENST00000303391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0001662"(behavioral fear response)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001964"(startle response)|go:"GO:0001976"(nervous system process involved in regulation of systemic arterial blood pressure)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006020"(inositol metabolic process)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006576"(cellular biogenic amine metabolic process)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007416"(synapse assembly)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0007616"(long-term memory)|go:"GO:0008104"(protein localization)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016358"(dendrite development)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016571"(histone methylation)|go:"GO:0016573"(histone acetylation)|go:"GO:0019230"(proprioception)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021591"(ventricular system development)|go:"GO:0032048"(cardiolipin metabolic process)|go:"GO:0035176"(social behavior)|go:"GO:0035197"(siRNA binding)|go:"GO:0042551"(neuron maturation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051151"(negative regulation of smooth muscle cell differentiation)|go:"GO:0051707"(response to other organism)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0098794"(postsynapse)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|go:"GO:1905643"(positive regulation of DNA methylation)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000820"(negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR017353(Methyl-CpG binding protein MeCP2)|mint:P51608|rcsb pdb:1QK9|rcsb pdb:3C2I|rcsb pdb:5BT2|rcsb pdb:6C1Y|rcsb pdb:6OGJ|rcsb pdb:6OGK|reactome:R-HSA-8986944|reactome:R-HSA-9022534|reactome:R-HSA-9022535|reactome:R-HSA-9022537|reactome:R-HSA-9022538|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9022702|reactome:R-HSA-9022707|reactome:R-HSA-9022927|dip:DIP-39983N ensembl:ENSG00000102753(gene)|ensembl:ENST00000261667(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0043657"(host cell)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR000225(Armadillo)|refseq:NP_002258.2|ensembl:ENSP00000261667|dip:DIP-27586N|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O00505|reactome:R-HSA-1169408|reactome:R-HSA-168276 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:7c5ZZAZsqV7AciGN4hzFNWJLeUk9606 rogid:kx/oTYWMYG7dhwJHvr1POLD6FTU9606 rigid:8qu/QD/5itLG+dPNu2Y1J+dhoXM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVC6 uniprotkb:Q15528 intact:EBI-394562|uniprotkb:Q9HA81|uniprotkb:Q9UNP7|uniprotkb:Q9Y2W0|uniprotkb:Q9Y660|uniprotkb:B3KN07|ensembl:ENSP00000251871 intact:EBI-394687|uniprotkb:Q5T8U0|uniprotkb:O76072|uniprotkb:B3KW83|uniprotkb:B3KWX4|ensembl:ENSP00000342343|ensembl:ENSP00000482438|ensembl:ENSP00000485880|ensembl:ENSP00000487580 psi-mi:med17_human(display_long)|uniprotkb:TRAP80(gene name synonym)|uniprotkb:MED17(gene name)|psi-mi:MED17(display_short)|uniprotkb:ARC77(gene name synonym)|uniprotkb:DRIP80(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 6(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP77(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 80 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 80 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 77 kDa component(gene name synonym)|uniprotkb:CRSP6(gene name synonym)|uniprotkb:DRIP77(gene name synonym) psi-mi:med22_human(display_long)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:MED22(gene name)|psi-mi:MED22(display_short)|uniprotkb:Surfeit locus protein 5(gene name synonym)|uniprotkb:SURF5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480680|imex:IM-26985-183 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004259.3|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|ensembl:ENSG00000042429(gene)|ensembl:ENST00000251871(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019313|mint:Q9NVC6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31451N refseq:NP_598395.1|refseq:NP_852468.1|ensembl:ENSG00000148297(gene)|ensembl:ENSG00000281022(gene)|ensembl:ENST00000343730(transcript)|ensembl:ENST00000610672(transcript)|ensembl:ENST00000629522(transcript)|ensembl:ENST00000631196(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR009332(Surfeit locus 5)|mint:Q15528|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 - - comment:"author score: 118" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:P2hRQOjWEtjw5V+lt7J9TP3VbpU9606 rogid:bAtK0Srk81ujvVt2Gj0+py7RCZY9606 rigid:ZvZMhJM9WtGS7uphzqxUV1S9eBo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVC6 uniprotkb:Q9P086 intact:EBI-394562|uniprotkb:Q9HA81|uniprotkb:Q9UNP7|uniprotkb:Q9Y2W0|uniprotkb:Q9Y660|uniprotkb:B3KN07|ensembl:ENSP00000251871 intact:EBI-394704|uniprotkb:Q6NS89|ensembl:ENSP00000293777 psi-mi:med17_human(display_long)|uniprotkb:TRAP80(gene name synonym)|uniprotkb:MED17(gene name)|psi-mi:MED17(display_short)|uniprotkb:ARC77(gene name synonym)|uniprotkb:DRIP80(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 6(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP77(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 80 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 80 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 77 kDa component(gene name synonym)|uniprotkb:CRSP6(gene name synonym)|uniprotkb:DRIP77(gene name synonym) psi-mi:med11_human(display_long)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:MED11(gene name)|psi-mi:MED11(display_short)|uniprotkb:HSPC296(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480680|imex:IM-26985-183 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004259.3|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|ensembl:ENSG00000042429(gene)|ensembl:ENST00000251871(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019313|mint:Q9NVC6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31451N refseq:NP_001291929.1|refseq:NP_001001683.1|ensembl:ENSG00000161920(gene)|ensembl:ENST00000293777(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019404|mint:Q9P086|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|go:"GO:0003712"(transcription coregulator activity) - - comment:"author score: 151" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:P2hRQOjWEtjw5V+lt7J9TP3VbpU9606 rogid:y7SZi5hIo5aOatJSZi98Hqt082A9606 rigid:ZvZMhJM9WtGS7uphzqxUV1S9eBo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVC6 uniprotkb:Q9H204 intact:EBI-394562|uniprotkb:Q9HA81|uniprotkb:Q9UNP7|uniprotkb:Q9Y2W0|uniprotkb:Q9Y660|uniprotkb:B3KN07|ensembl:ENSP00000251871 intact:EBI-514199|uniprotkb:Q9BZJ5|ensembl:ENSP00000237380 psi-mi:med17_human(display_long)|uniprotkb:TRAP80(gene name synonym)|uniprotkb:MED17(gene name)|psi-mi:MED17(display_short)|uniprotkb:ARC77(gene name synonym)|uniprotkb:DRIP80(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 6(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP77(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 80 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 80 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 77 kDa component(gene name synonym)|uniprotkb:CRSP6(gene name synonym)|uniprotkb:DRIP77(gene name synonym) psi-mi:med28_human(display_long)|uniprotkb:Mediator complex subunit 28(gene name synonym)|uniprotkb:Tumor angiogenesis marker EG-1(gene name synonym)|uniprotkb:Endothelial-derived protein 1(gene name synonym)|uniprotkb:Merlin and Grb2-interacting cytoskeletal protein(gene name synonym)|uniprotkb:MED28(gene name)|psi-mi:MED28(display_short)|uniprotkb:EG1(gene name synonym)|uniprotkb:FKSG20(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480680|imex:IM-26985-183 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004259.3|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|ensembl:ENSG00000042429(gene)|ensembl:ENST00000251871(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019313|mint:Q9NVC6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31451N refseq:NP_079481.2|ensembl:ENSG00000118579(gene)|ensembl:ENST00000237380(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0051151"(negative regulation of smooth muscle cell differentiation)|interpro:IPR021640|mint:Q9H204|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 - - comment:"author score: 164" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:P2hRQOjWEtjw5V+lt7J9TP3VbpU9606 rogid:1gt/0vP7vWJ+M1fU+qZPcWGj34U9606 rigid:ZvZMhJM9WtGS7uphzqxUV1S9eBo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVC6 uniprotkb:Q6P2C8 intact:EBI-394562|uniprotkb:Q9HA81|uniprotkb:Q9UNP7|uniprotkb:Q9Y2W0|uniprotkb:Q9Y660|uniprotkb:B3KN07|ensembl:ENSP00000251871 intact:EBI-394603|uniprotkb:Q4F964|uniprotkb:O95401|uniprotkb:Q5VTA4|uniprotkb:Q5VTA5|uniprotkb:Q9BU57|uniprotkb:Q9NYR4|uniprotkb:V9GYV9|ensembl:ENSP00000292035 psi-mi:med17_human(display_long)|uniprotkb:TRAP80(gene name synonym)|uniprotkb:MED17(gene name)|psi-mi:MED17(display_short)|uniprotkb:ARC77(gene name synonym)|uniprotkb:DRIP80(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 6(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP77(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 80 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 80 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 77 kDa component(gene name synonym)|uniprotkb:CRSP6(gene name synonym)|uniprotkb:DRIP77(gene name synonym) psi-mi:med27_human(display_long)|uniprotkb:MED27(gene name)|psi-mi:MED27(display_short)|uniprotkb:Mediator complex subunit 27(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 8(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP34(gene name synonym)|uniprotkb:P37 TRAP/SMCC/PC2 subunit(gene name synonym)|uniprotkb:CRSP34(gene name synonym)|uniprotkb:CRSP8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480680|imex:IM-26985-183 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004259.3|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|ensembl:ENSG00000042429(gene)|ensembl:ENST00000251871(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019313|mint:Q9NVC6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31451N refseq:NP_001240811.1|refseq:NP_004260.2|refseq:NP_001240810.1|dip:DIP-31465N|ensembl:ENSG00000160563(gene)|ensembl:ENST00000292035(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021627|mint:Q6P2C8|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 - - comment:"author score: 167" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:P2hRQOjWEtjw5V+lt7J9TP3VbpU9606 rogid:V1clNhbtflCzCkC7OnaHGYrmQp89606 rigid:ZvZMhJM9WtGS7uphzqxUV1S9eBo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVC6 uniprotkb:Q96G25 intact:EBI-394562|uniprotkb:Q9HA81|uniprotkb:Q9UNP7|uniprotkb:Q9Y2W0|uniprotkb:Q9Y660|uniprotkb:B3KN07|ensembl:ENSP00000251871 intact:EBI-394405|uniprotkb:A9IZ91|uniprotkb:Q96FQ4|uniprotkb:A9IZ92|uniprotkb:Q5JUY8|ensembl:ENSP00000361535 psi-mi:med17_human(display_long)|uniprotkb:TRAP80(gene name synonym)|uniprotkb:MED17(gene name)|psi-mi:MED17(display_short)|uniprotkb:ARC77(gene name synonym)|uniprotkb:DRIP80(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 6(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP77(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 80 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 80 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 77 kDa component(gene name synonym)|uniprotkb:CRSP6(gene name synonym)|uniprotkb:DRIP77(gene name synonym) psi-mi:med8_human(display_long)|uniprotkb:MED8(gene name)|psi-mi:MED8(display_short)|uniprotkb:Mediator complex subunit 8(gene name synonym)|uniprotkb:Activator-recruited cofactor 32 kDa component(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480680|imex:IM-26985-183 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004259.3|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|ensembl:ENSG00000042429(gene)|ensembl:ENST00000251871(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019313|mint:Q9NVC6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31451N refseq:NP_443109.2|refseq:NP_963836.2|refseq:NP_001001653.1|ensembl:ENSG00000159479(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|mint:Q96G25|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENST00000372457(transcript) - - comment:"author score: 171" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:P2hRQOjWEtjw5V+lt7J9TP3VbpU9606 rogid:e/ye7rfa2E1XOPb5vVhI9Nvqmxw9606 rigid:ZvZMhJM9WtGS7uphzqxUV1S9eBo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVC6 uniprotkb:Q96HR3 intact:EBI-394562|uniprotkb:Q9HA81|uniprotkb:Q9UNP7|uniprotkb:Q9Y2W0|uniprotkb:Q9Y660|uniprotkb:B3KN07|ensembl:ENSP00000251871 intact:EBI-394659|uniprotkb:C6GKU9|intact:EBI-11137618|ensembl:ENSP00000297347 psi-mi:med17_human(display_long)|uniprotkb:TRAP80(gene name synonym)|uniprotkb:MED17(gene name)|psi-mi:MED17(display_short)|uniprotkb:ARC77(gene name synonym)|uniprotkb:DRIP80(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 6(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP77(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 80 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 80 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 77 kDa component(gene name synonym)|uniprotkb:CRSP6(gene name synonym)|uniprotkb:DRIP77(gene name synonym) psi-mi:med30_human(display_long)|uniprotkb:TRAP25(gene name synonym)|uniprotkb:MED30(gene name)|psi-mi:MED30(display_short)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)|uniprotkb:TRAP/Mediator complex component TRAP25(gene name synonym)|uniprotkb:THRAP6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480680|imex:IM-26985-183 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004259.3|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|ensembl:ENSG00000042429(gene)|ensembl:ENST00000251871(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019313|mint:Q9NVC6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31451N refseq:NP_542382.1|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|mint:Q96HR3|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001269915.1|ensembl:ENSG00000164758(gene)|ensembl:ENST00000297347(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity) - - comment:"author score: 181" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:P2hRQOjWEtjw5V+lt7J9TP3VbpU9606 rogid:dUgR7zxbKAcYqPKb8teHBLgUhWY9606 rigid:ZvZMhJM9WtGS7uphzqxUV1S9eBo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BUE0 uniprotkb:Q5T9A4 intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184 intact:EBI-1384144|uniprotkb:Q6ZRB5|uniprotkb:Q9BUK4|uniprotkb:Q9ULE7|uniprotkb:A8K3H1|ensembl:ENSP00000500094 psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym) psi-mi:atd3b_human(display_long)|uniprotkb:TOB3(gene name synonym)|uniprotkb:AAA-TOB3(gene name synonym)|uniprotkb:KIAA1273(gene name synonym)|uniprotkb:ATAD3B(gene name)|psi-mi:ATAD3B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480704|imex:IM-26985-335 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 refseq:NP_114127.3|refseq:NP_001304167.1|ensembl:ENSG00000160072(gene)|ensembl:ENST00000673477(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR021911|interpro:IPR027417|interpro:IPR039188|mint:Q5T9A4|reactome:R-HSA-6798695 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606 rogid:2W52iPQhTBU2apShm8xhfenV1mU9606 rigid:y+DgNPAjId00fa990t/7jp7XPoU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BUE0 uniprotkb:P52435 intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184 intact:EBI-394753|uniprotkb:O43375|uniprotkb:A5D6V8|ensembl:ENSP00000292614 psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym) psi-mi:rpb11_human(display_long)|uniprotkb:POLR2J(gene name)|psi-mi:POLR2J(display_short)|uniprotkb:POLR2J1(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II subunit J-1(gene name synonym)|uniprotkb:RNA polymerase II 13.3 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480704|imex:IM-26985-335 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 refseq:NP_006225.1|ensembl:ENSG00000005075(gene)|ensembl:ENST00000292614(transcript)|go:"GO:0001055"(RNA polymerase II activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0030275"(LRR domain binding)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR008193(DNA-directed RNA polymerase Rpb11, 13-16 kDa subunit, conserved site)|interpro:IPR009025(DNA-directed RNA polymerase, RBP11-like)|interpro:IPR036603|interpro:IPR037685|mint:P52435|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32913N - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606 rogid:jK/DlwFrHHuEJ0Ns3wRoB3icmsA9606 rigid:y+DgNPAjId00fa990t/7jp7XPoU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BUE0 uniprotkb:P62487 intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184 intact:EBI-347928|ensembl:ENSP00000301788|uniprotkb:P52433|uniprotkb:Q2M1Z4|uniprotkb:B2R5C0 psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym) psi-mi:rpb7_human(display_long)|uniprotkb:POLR2G(gene name)|psi-mi:POLR2G(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit G(gene name synonym)|uniprotkb:RPB7(gene name synonym)|uniprotkb:RNA polymerase II 19 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480704|imex:IM-26985-335 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 ensembl:ENSG00000168002(gene)|ensembl:ENST00000301788(transcript)|go:"GO:0000291"(nuclear-transcribed mRNA catabolic process, exonucleolytic)|go:"GO:0000932"(P-body)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006915"(apoptotic process)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR003029(S1, RNA binding)|interpro:IPR005576(RNA polymerase Rpb7, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR036898|mint:P62487|rcsb pdb:2C35|rcsb pdb:5IYA|rcsb pdb:5IY6|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|rcsb pdb:5IY7|reactome:R-HSA-167200|reactome:R-HSA-167238|rcsb pdb:5IY8|rcsb pdb:5IY9|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-5601884|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|refseq:NP_002687.1|dip:DIP-32663N - - comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606 rogid:MtnIweuhSqLFov0c40uOiwv8Eas9606 rigid:y+DgNPAjId00fa990t/7jp7XPoU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BUE0 uniprotkb:P52434 intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184 intact:EBI-359505|uniprotkb:P53802|uniprotkb:Q969R0|ensembl:ENSP00000392913|uniprotkb:C9J413|uniprotkb:C9JBJ6|uniprotkb:C9JCU7|uniprotkb:C9JUA8 psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym) psi-mi:rpab3_human(display_long)|uniprotkb:POLR2H(gene name)|psi-mi:POLR2H(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit H(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I, II, and III 17.1 kDa polypeptide(gene name synonym)|uniprotkb:RPB17(gene name synonym)|uniprotkb:RPB8 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480704|imex:IM-26985-335 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 ensembl:ENSG00000163882(gene)|ensembl:ENST00000456318(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032993"(protein-DNA complex)|interpro:IPR005570(RNA polymerase, Rpb8)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:P52434|rcsb pdb:2F3I|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|refseq:NP_006223.2|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|rcsb pdb:7AE3|reactome:R-HSA-1834949|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-427413|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-203927|refseq:NP_001265627.1|refseq:NP_001265628.1|refseq:NP_001265629.1|refseq:NP_001265644.1|refseq:NP_001265643.1|refseq:XP_006713729.1|refseq:XP_006713730.1|refseq:XP_016862125.1|refseq:XP_016862126.1|dip:DIP-27556N - - comment:"author score: 35" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606 rogid:h7BRWDi8wRbnw/FcFo25bnlVNkE9606 rigid:y+DgNPAjId00fa990t/7jp7XPoU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BUE0 uniprotkb:P24863 intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184 intact:EBI-395261|uniprotkb:Q9H543|ensembl:ENSP00000428982|uniprotkb:B4DPZ1 psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym) psi-mi:ccnc_human(display_long)|uniprotkb:CCNC(gene name)|psi-mi:CCNC(display_short)|uniprotkb:SRB11 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480704|imex:IM-26985-335 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 ensembl:ENSG00000112237(gene)|ensembl:ENST00000520429(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR028367|interpro:IPR036915|interpro:IPR043198|mint:P24863|rcsb pdb:5XQX|rcsb pdb:5XS2|rcsb pdb:6QTG|rcsb pdb:6QTJ|rcsb pdb:6R3S|rcsb pdb:6T41|rcsb pdb:6TPA|rcsb pdb:6Y0A|reactome:R-HSA-1989781|reactome:R-HSA-2122947|reactome:R-HSA-212436|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-381340|rcsb pdb:3RGF|rcsb pdb:4CRL|rcsb pdb:4F6S|rcsb pdb:4F6U|rcsb pdb:4F6W|rcsb pdb:4F70|rcsb pdb:4F7J|rcsb pdb:4F7L|rcsb pdb:4F7N|rcsb pdb:4F7S|rcsb pdb:4G6L|rcsb pdb:5BNJ|rcsb pdb:5CEI|rcsb pdb:5FGK|rcsb pdb:5HBE|rcsb pdb:5HBH|rcsb pdb:5HBJ|rcsb pdb:5HNB|rcsb pdb:5HVY|rcsb pdb:5I5Z|rcsb pdb:5ICP|rcsb pdb:5IDN|rcsb pdb:5IDP|refseq:NP_005181.2|refseq:NP_001013417.1|dip:DIP-32920N - - comment:"author score: 43" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606 rogid:Gu327q98H8ggQoYCb4UnR2Mcsyg9606 rigid:y+DgNPAjId00fa990t/7jp7XPoU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BUE0 uniprotkb:P19388 intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym) psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480704|imex:IM-26985-335 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N - - comment:"author score: 45" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rigid:y+DgNPAjId00fa990t/7jp7XPoU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BUE0 uniprotkb:P30876 intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184 intact:EBI-394712|uniprotkb:Q8IZ61|uniprotkb:A8K1A8|ensembl:ENSP00000312735|ensembl:ENSP00000370625 psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym) psi-mi:rpb2_human(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit B(gene name synonym)|uniprotkb:RNA polymerase II subunit B2(gene name synonym)|uniprotkb:RNA polymerase II subunit 2(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 140 kDa polypeptide(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480704|imex:IM-26985-335 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 refseq:NP_000929.1|refseq:NP_001290197.1|refseq:NP_001290198.1|ensembl:ENSG00000047315(gene)|ensembl:ENST00000314595(transcript)|ensembl:ENST00000381227(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|mint:P30876|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32910N - - comment:"author score: 47" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606 rogid:YhEjtfLk2QnbRPefOp8ZHX0ejak9606 rigid:y+DgNPAjId00fa990t/7jp7XPoU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BUE0 uniprotkb:P24928 intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184 intact:EBI-295301|uniprotkb:A6NN93|uniprotkb:B9EH88|uniprotkb:Q6NX41|intact:EBI-17957133|intact:EBI-14758660|intact:EBI-13324911|intact:EBI-23311874 psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym) psi-mi:rpb1_human(display_long)|uniprotkb:POLR2A(gene name)|psi-mi:POLR2A(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit A(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:POLR2(gene name synonym)|uniprotkb:RNA-directed RNA polymerase II subunit RPB1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480704|imex:IM-26985-335 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 refseq:NP_000928.1|mint:P24928|dip:DIP-29011N|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0019900"(kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:2GHQ|rcsb pdb:2GHT|rcsb pdb:2LTO|rcsb pdb:3D9K|rcsb pdb:3D9L|rcsb pdb:3D9M|rcsb pdb:3D9N|rcsb pdb:3D9O|rcsb pdb:3D9P|rcsb pdb:4JXT|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:5M3H|rcsb pdb:5M3J|rcsb pdb:6DRD|rcsb pdb:6F5P|rcsb pdb:6G0R|rcsb pdb:6IC8|rcsb pdb:6IC9|rcsb pdb:6O9L|rcsb pdb:6Q5Y|rcsb pdb:6XKB|rcsb pdb:6XRE|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095 - - comment:"author score: 47" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606 rogid:Si2fgh4AMaNtlzvSQhvsuPusX7s9606 rigid:y+DgNPAjId00fa990t/7jp7XPoU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BUE0 uniprotkb:P49336 intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184 intact:EBI-394377|uniprotkb:Q5VUF3|uniprotkb:Q6ISB5|ensembl:ENSP00000370938 psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym) psi-mi:cdk8_human(display_long)|uniprotkb:CDK8(gene name)|psi-mi:CDK8(display_short)|uniprotkb:Cell division protein kinase 8(gene name synonym)|uniprotkb:Mediator of RNA polymerase II transcription subunit CDK8(gene name synonym)|uniprotkb:Mediator complex subunit CDK8(gene name synonym)|uniprotkb:Protein kinase K35(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480704|imex:IM-26985-335 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 refseq:NP_001305297.1|refseq:NP_001251.1|ensembl:ENSG00000132964(gene)|ensembl:ENST00000381527(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006468"(protein phosphorylation)|rcsb pdb:5FGK|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0016592"(mediator complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P49336|rcsb pdb:3RGF|rcsb pdb:4CRL|rcsb pdb:4F6S|rcsb pdb:4F6U|rcsb pdb:4F6W|rcsb pdb:4F70|rcsb pdb:4F7J|rcsb pdb:4F7L|rcsb pdb:4F7N|rcsb pdb:4F7S|rcsb pdb:4G6L|rcsb pdb:5BNJ|rcsb pdb:5CEI|rcsb pdb:5HBE|rcsb pdb:5HBH|rcsb pdb:5HBJ|rcsb pdb:5HNB|rcsb pdb:5HVY|rcsb pdb:5I5Z|rcsb pdb:5ICP|rcsb pdb:5IDN|rcsb pdb:5IDP|rcsb pdb:5XQX|rcsb pdb:5XS2|rcsb pdb:6QTG|rcsb pdb:6QTJ|rcsb pdb:6R3S|rcsb pdb:6T41|rcsb pdb:6TPA|rcsb pdb:6Y0A|reactome:R-HSA-1989781|reactome:R-HSA-2122947|reactome:R-HSA-212436|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-381340|dip:DIP-32595N - - comment:"author score: 49" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606 rogid:f+78iyCfA9osCQ82uY6reu3JKzo9606 rigid:y+DgNPAjId00fa990t/7jp7XPoU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BUE0 uniprotkb:P19387 intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184 intact:EBI-394729|uniprotkb:O15161|ensembl:ENSP00000219252 psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym) psi-mi:rpb3_human(display_long)|uniprotkb:POLR2C(gene name)|psi-mi:POLR2C(display_short)|uniprotkb:A-152E5.7(orf name)|uniprotkb:DNA-directed RNA polymerase II subunit C(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 33 kDa polypeptide(gene name synonym)|uniprotkb:RPB31(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480704|imex:IM-26985-335 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 refseq:NP_116558.1|ensembl:ENSG00000102978(gene)|ensembl:ENST00000219252(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001514(DNA-directed RNA polymerase, 30-40 kDa subunit, conserved site)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR036603|interpro:IPR036643|mint:P19387|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32911N - - comment:"author score: 53" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606 rogid:UXFC+i+QqB2WRgL9OiYSQ66L36c9606 rigid:y+DgNPAjId00fa990t/7jp7XPoU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BUE0 uniprotkb:Q9UHV7 intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184 intact:EBI-394440|uniprotkb:O60334|uniprotkb:B2RU05|ensembl:ENSP00000380888 psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym) psi-mi:med13_human(display_long)|uniprotkb:TRAP240(gene name synonym)|uniprotkb:MED13(gene name)|psi-mi:MED13(display_short)|uniprotkb:ARC250(gene name synonym)|uniprotkb:KIAA0593(gene name synonym)|uniprotkb:Mediator complex subunit 13(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 240 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 1(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex component DRIP250(gene name synonym)|uniprotkb:Activator-recruited cofactor 250 kDa component(gene name synonym)|uniprotkb:THRAP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480704|imex:IM-26985-335 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 refseq:NP_005112.2|ensembl:ENSG00000108510(gene)|ensembl:ENST00000397786(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR009401(TRAP240)|interpro:IPR041285|mint:Q9UHV7|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31468N - - comment:"author score: 53" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606 rogid:ZNWwmsetsKLA56joRzRL0UKjq9Y9606 rigid:y+DgNPAjId00fa990t/7jp7XPoU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BUE0 uniprotkb:P36954 intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184 intact:EBI-395202|uniprotkb:Q6NW05|uniprotkb:B2R5J2|ensembl:ENSP00000221859 psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym) psi-mi:rpb9_human(display_long)|uniprotkb:POLR2I(gene name)|psi-mi:POLR2I(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit I(gene name synonym)|uniprotkb:RNA polymerase II 14.5 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480704|imex:IM-26985-335 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 refseq:NP_006224.1|ensembl:ENSG00000105258(gene)|ensembl:ENST00000221859(transcript)|go:"GO:0001193"(maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034012|mint:P36954|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32917N - - comment:"author score: 55" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606 rogid:YZUW2UDzj1RhCC46iaX1LvYayNA9606 rigid:y+DgNPAjId00fa990t/7jp7XPoU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BUE0 uniprotkb:Q71F56 intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184 intact:EBI-394435|uniprotkb:A1L469|uniprotkb:Q68DN4|uniprotkb:Q9H8C0|uniprotkb:Q9NSY9|uniprotkb:Q9UFD8|uniprotkb:Q9UPX5|ensembl:ENSP00000281928 psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym) psi-mi:md13l_human(display_long)|uniprotkb:Mediator complex subunit 13-like(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 2(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 240 kDa component-like(gene name synonym)|uniprotkb:MED13L(gene name)|psi-mi:MED13L(display_short)|uniprotkb:KIAA1025(gene name synonym)|uniprotkb:PROSIT240(gene name synonym)|uniprotkb:THRAP2(gene name synonym)|uniprotkb:TRAP240L(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480704|imex:IM-26985-335 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 refseq:NP_056150.1|ensembl:ENSG00000123066(gene)|ensembl:ENST00000281928(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR009401(TRAP240)|interpro:IPR021643|interpro:IPR041285|mint:Q71F56|reactome:R-HSA-1989781|reactome:R-HSA-381340 - - comment:"author score: 67" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606 rogid:Zdj5dM/HEWW8zS27yaXsR+ZOxZs9606 rigid:y+DgNPAjId00fa990t/7jp7XPoU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BUE0 uniprotkb:Q93074 intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184 intact:EBI-394357|uniprotkb:O15410|uniprotkb:O75557|uniprotkb:Q9UHV6|uniprotkb:Q9UND7|ensembl:ENSP00000363193 psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym) psi-mi:med12_human(display_long)|uniprotkb:TRAP230(gene name synonym)|uniprotkb:MED12(gene name)|psi-mi:MED12(display_short)|uniprotkb:ARC240(gene name synonym)|uniprotkb:CAGH45(gene name synonym)|uniprotkb:HOPA(gene name synonym)|uniprotkb:KIAA0192(gene name synonym)|uniprotkb:Mediator complex subunit 12(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 230 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 240 kDa component(gene name synonym)|uniprotkb:CAG repeat protein 45(gene name synonym)|uniprotkb:OPA-containing protein(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 11 protein(gene name synonym)|uniprotkb:TNRC11(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480704|imex:IM-26985-335 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 refseq:NP_005111.2|ensembl:ENSG00000184634(gene)|ensembl:ENST00000374080(transcript)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0090245"(axis elongation involved in somitogenesis)|go:"GO:1990403"(embryonic brain development)|interpro:IPR019035|interpro:IPR021989|interpro:IPR021990|mint:Q93074|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0014044"(Schwann cell development)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|dip:DIP-31459N - - comment:"author score: 76" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606 rogid:soNqTi3/n+qnj+P4AX/cPJzTK2U9606 rigid:y+DgNPAjId00fa990t/7jp7XPoU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BUE0 uniprotkb:Q9BTT4 intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184 intact:EBI-394354|uniprotkb:C6G491|ensembl:ENSP00000255764 psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym) psi-mi:med10_human(display_long)|uniprotkb:MED10(gene name)|psi-mi:MED10(display_short)|uniprotkb:L6(orf name)|uniprotkb:TRG17(orf name)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Transformation-related gene 17 protein(gene name synonym)|uniprotkb:Transformation-related gene 20 protein(gene name synonym)|uniprotkb:TRG20(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480704|imex:IM-26985-335 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 ensembl:ENSG00000133398(gene)|ensembl:ENST00000255764(transcript)|refseq:NP_115662.2|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019145|mint:Q9BTT4|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|go:"GO:0000151"(ubiquitin ligase complex)|dip:DIP-31457N - - comment:"author score: 88" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606 rogid:LzJW7C8kl2pWmffOjo8S/FNSS9I9606 rigid:y+DgNPAjId00fa990t/7jp7XPoU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BUE0 uniprotkb:Q15528 intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184 intact:EBI-394687|uniprotkb:Q5T8U0|uniprotkb:O76072|uniprotkb:B3KW83|uniprotkb:B3KWX4|ensembl:ENSP00000342343|ensembl:ENSP00000482438|ensembl:ENSP00000485880|ensembl:ENSP00000487580 psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym) psi-mi:med22_human(display_long)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:MED22(gene name)|psi-mi:MED22(display_short)|uniprotkb:Surfeit locus protein 5(gene name synonym)|uniprotkb:SURF5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480704|imex:IM-26985-335 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 refseq:NP_598395.1|refseq:NP_852468.1|ensembl:ENSG00000148297(gene)|ensembl:ENSG00000281022(gene)|ensembl:ENST00000343730(transcript)|ensembl:ENST00000610672(transcript)|ensembl:ENST00000629522(transcript)|ensembl:ENST00000631196(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR009332(Surfeit locus 5)|mint:Q15528|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 - - comment:"author score: 93" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606 rogid:bAtK0Srk81ujvVt2Gj0+py7RCZY9606 rigid:y+DgNPAjId00fa990t/7jp7XPoU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BUE0 uniprotkb:Q15648 intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184 intact:EBI-394459|uniprotkb:A2RRQ6|uniprotkb:O43810|uniprotkb:O75447|uniprotkb:Q6P9H7|uniprotkb:Q6PK58|uniprotkb:Q9HD39|ensembl:ENSP00000300651 psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym) psi-mi:med1_human(display_long)|uniprotkb:TRIP2(gene name synonym)|uniprotkb:MED1(gene name)|psi-mi:MED1(display_short)|uniprotkb:ARC205(gene name synonym)|uniprotkb:DRIP205(gene name synonym)|uniprotkb:TRAP220(gene name synonym)|uniprotkb:Activator-recruited cofactor 205 kDa component(gene name synonym)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-binding protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 220 kDa component(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 2(gene name synonym)|uniprotkb:p53 regulatory protein RB18A(gene name synonym)|uniprotkb:Vitamin D receptor-interacting protein complex component DRIP205(gene name synonym)|uniprotkb:CRSP1(gene name synonym)|uniprotkb:CRSP200(gene name synonym)|uniprotkb:DRIP230(gene name synonym)|uniprotkb:PBP(gene name synonym)|uniprotkb:PPARBP(gene name synonym)|uniprotkb:PPARGBP(gene name synonym)|uniprotkb:RB18A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480704|imex:IM-26985-335 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 refseq:NP_004765.2|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR019680|mint:Q15648|rcsb pdb:1RJK|rcsb pdb:1RK3|rcsb pdb:1RKG|rcsb pdb:1RKH|rcsb pdb:2O4J|rcsb pdb:2O4R|rcsb pdb:2ZFX|rcsb pdb:3A2H|rcsb pdb:3AUN|rcsb pdb:3VJS|rcsb pdb:3VJT|rcsb pdb:3VRT|rcsb pdb:3VRU|rcsb pdb:3VRV|rcsb pdb:3VRW|rcsb pdb:3W0G|rcsb pdb:3W0H|rcsb pdb:3W0I|rcsb pdb:3W0J|rcsb pdb:3W5P|rcsb pdb:3W5Q|rcsb pdb:3W5R|rcsb pdb:3W5T|rcsb pdb:3WT5|rcsb pdb:3WT6|rcsb pdb:3WT7|rcsb pdb:3WTQ|rcsb pdb:4YNK|rcsb pdb:5AWJ|rcsb pdb:5AWK|rcsb pdb:5B41|rcsb pdb:5B5B|rcsb pdb:5GIC|rcsb pdb:5GID|rcsb pdb:5GIE|rcsb pdb:5XPM|rcsb pdb:5XPN|rcsb pdb:5XPO|rcsb pdb:5XPP|rcsb pdb:5XUQ|rcsb pdb:5XZF|rcsb pdb:5XZH|rcsb pdb:5ZWE|rcsb pdb:5ZWF|rcsb pdb:5ZWH|rcsb pdb:5ZWI|rcsb pdb:6D94|rcsb pdb:6JEZ|rcsb pdb:6K5O|rcsb pdb:6ONJ|rcsb pdb:7C7V|rcsb pdb:7C7W|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9707564|reactome:R-HSA-9707616|ensembl:ENSG00000125686(gene)|ensembl:ENST00000300651(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003406"(retinal pigment epithelium development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0050693"(LBD domain binding)|dip:DIP-24212N - - comment:"author score: 93" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606 rogid:A4EIAri9zYycSlTA7s6NzbOi9n49606 rigid:y+DgNPAjId00fa990t/7jp7XPoU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BUE0 uniprotkb:A0JLT2 intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184 intact:EBI-394430|uniprotkb:Q8IV02|intact:EBI-394763|uniprotkb:Q8IZD1 psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym) psi-mi:med19_human(display_long)|uniprotkb:MED19(gene name)|psi-mi:MED19(display_short)|uniprotkb:LCMR1(gene name synonym)|uniprotkb:Lung cancer metastasis-related protein 1(gene name synonym)|uniprotkb:Mediator complex subunit 19(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480704|imex:IM-26985-335 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 refseq:NP_001304007.1|refseq:NP_703151.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR019403|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|mint:A0JLT2|dip:DIP-31467N - - comment:"author score: 94" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606 rogid:zcHhU2hQvuTpkFZz/xEKYmjrwOA9606 rigid:y+DgNPAjId00fa990t/7jp7XPoU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BUE0 uniprotkb:O95402 intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184 intact:EBI-394392|uniprotkb:A1A4S3|uniprotkb:Q0VGB6|intact:EBI-28974475|ensembl:ENSP00000263390 psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym) psi-mi:med26_human(display_long)|uniprotkb:ARC70(gene name synonym)|uniprotkb:MED26(gene name)|psi-mi:MED26(display_short)|uniprotkb:Mediator complex subunit 26(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 7(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP70(gene name synonym)|uniprotkb:Activator-recruited cofactor 70 kDa component(gene name synonym)|uniprotkb:CRSP7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480704|imex:IM-26985-335 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 ensembl:ENSP00000263390|ensembl:ENST00000611692|ensembl:ENSP00000484490|refseq:NP_004822.2|ensembl:ENSG00000105085(gene)|ensembl:ENST00000263390(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR017923|interpro:IPR031416|interpro:IPR031417|interpro:IPR035441|interpro:IPR042376|mint:O95402|rcsb pdb:5ODD|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31464N - - comment:"author score: 96" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606 rogid:1kRmQ+QH5uQkKVfjo2Rc2SkAyKc9606 rigid:y+DgNPAjId00fa990t/7jp7XPoU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BUE0 uniprotkb:O60244 intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184 intact:EBI-394489|uniprotkb:Q4KMR7|uniprotkb:Q9UNB3|ensembl:ENSP00000323720 psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym) psi-mi:med14_human(display_long)|uniprotkb:TRAP170(gene name synonym)|uniprotkb:MED14(gene name)|psi-mi:MED14(display_short)|uniprotkb:ARC150(gene name synonym)|uniprotkb:DRIP150(gene name synonym)|uniprotkb:EXLM1(gene name synonym)|uniprotkb:RGR1(gene name synonym)|uniprotkb:Mediator complex subunit 14(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 2(gene name synonym)|uniprotkb:RGR1 homolog(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP150(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 150 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 170 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 150 kDa component(gene name synonym)|uniprotkb:CRSP2(gene name synonym)|uniprotkb:CXorf4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480704|imex:IM-26985-335 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 refseq:NP_004220.2|ensembl:ENSG00000180182(gene)|ensembl:ENST00000324817(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR013947(Mediator complex, subunit MED14)|mint:O60244|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31460N - - comment:"author score: 96" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606 rogid:73RBAnwmB4Lyl/kcsg7NKSUmA4c9606 rigid:y+DgNPAjId00fa990t/7jp7XPoU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BUE0 uniprotkb:Q9H204 intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184 intact:EBI-514199|uniprotkb:Q9BZJ5|ensembl:ENSP00000237380 psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym) psi-mi:med28_human(display_long)|uniprotkb:Mediator complex subunit 28(gene name synonym)|uniprotkb:Tumor angiogenesis marker EG-1(gene name synonym)|uniprotkb:Endothelial-derived protein 1(gene name synonym)|uniprotkb:Merlin and Grb2-interacting cytoskeletal protein(gene name synonym)|uniprotkb:MED28(gene name)|psi-mi:MED28(display_short)|uniprotkb:EG1(gene name synonym)|uniprotkb:FKSG20(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480704|imex:IM-26985-335 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 refseq:NP_079481.2|ensembl:ENSG00000118579(gene)|ensembl:ENST00000237380(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0051151"(negative regulation of smooth muscle cell differentiation)|interpro:IPR021640|mint:Q9H204|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 - - comment:"author score: 102" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606 rogid:1gt/0vP7vWJ+M1fU+qZPcWGj34U9606 rigid:y+DgNPAjId00fa990t/7jp7XPoU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BUE0 uniprotkb:Q9NWA0 intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184 intact:EBI-394653|ensembl:ENSP00000268711 psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym) psi-mi:med9_human(display_long)|uniprotkb:MED9(gene name)|psi-mi:MED9(display_short)|uniprotkb:Mediator complex subunit 9(gene name synonym)|uniprotkb:MED25(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480704|imex:IM-26985-335 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 refseq:NP_060489.1|ensembl:ENSG00000141026(gene)|ensembl:ENST00000268711(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR011425(RNA polymerase II transcription mediator)|interpro:IPR037212|interpro:IPR039242|mint:Q9NWA0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 - - comment:"author score: 102" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606 rogid:VSYpA1Aqh2FEaZIEF/6iCIpoPEc9606 rigid:y+DgNPAjId00fa990t/7jp7XPoU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BUE0 uniprotkb:Q9H944 intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184 intact:EBI-394644|uniprotkb:Q9Y429|uniprotkb:O95821|uniprotkb:Q5T8J4|uniprotkb:B4DE08|ensembl:ENSP00000265350 psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym) psi-mi:med20_human(display_long)|uniprotkb:TRFP(gene name synonym)|uniprotkb:MED20(gene name)|psi-mi:MED20(display_short)|uniprotkb:Mediator complex subunit 20(gene name synonym)|uniprotkb:TRF-proximal protein homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480704|imex:IM-26985-335 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 refseq:NP_004266.2|refseq:NP_001292384.1|refseq:NP_001292385.1|refseq:NP_001292386.1|go:"GO:0016592"(mediator complex)|interpro:IPR013921(TATA-binding related factor)|mint:Q9H944|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000124641(gene)|ensembl:ENST00000265350(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|dip:DIP-31449N - - comment:"author score: 103" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606 rogid:MpYOrONH6+0lKIlO6J+Szjzkw2A9606 rigid:y+DgNPAjId00fa990t/7jp7XPoU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BUE0 uniprotkb:Q9NVC6 intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184 intact:EBI-394562|uniprotkb:Q9HA81|uniprotkb:Q9UNP7|uniprotkb:Q9Y2W0|uniprotkb:Q9Y660|uniprotkb:B3KN07|ensembl:ENSP00000251871 psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym) psi-mi:med17_human(display_long)|uniprotkb:TRAP80(gene name synonym)|uniprotkb:MED17(gene name)|psi-mi:MED17(display_short)|uniprotkb:ARC77(gene name synonym)|uniprotkb:DRIP80(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 6(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP77(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 80 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 80 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 77 kDa component(gene name synonym)|uniprotkb:CRSP6(gene name synonym)|uniprotkb:DRIP77(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480704|imex:IM-26985-335 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 refseq:NP_004259.3|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|ensembl:ENSG00000042429(gene)|ensembl:ENST00000251871(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019313|mint:Q9NVC6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31451N - - comment:"author score: 107" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606 rogid:P2hRQOjWEtjw5V+lt7J9TP3VbpU9606 rigid:y+DgNPAjId00fa990t/7jp7XPoU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BUE0 uniprotkb:Q9NPJ6 intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184 intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648 psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym) psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480704|imex:IM-26985-335 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 - - comment:"author score: 111" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606 rogid:Bept2Oec50gruA9e4pf+eEUiANM9606 rigid:y+DgNPAjId00fa990t/7jp7XPoU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BUE0 uniprotkb:Q96G25 intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184 intact:EBI-394405|uniprotkb:A9IZ91|uniprotkb:Q96FQ4|uniprotkb:A9IZ92|uniprotkb:Q5JUY8|ensembl:ENSP00000361535 psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym) psi-mi:med8_human(display_long)|uniprotkb:MED8(gene name)|psi-mi:MED8(display_short)|uniprotkb:Mediator complex subunit 8(gene name synonym)|uniprotkb:Activator-recruited cofactor 32 kDa component(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480704|imex:IM-26985-335 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 refseq:NP_443109.2|refseq:NP_963836.2|refseq:NP_001001653.1|ensembl:ENSG00000159479(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|mint:Q96G25|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENST00000372457(transcript) - - comment:"author score: 117" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606 rogid:e/ye7rfa2E1XOPb5vVhI9Nvqmxw9606 rigid:y+DgNPAjId00fa990t/7jp7XPoU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BUE0 uniprotkb:Q9P086 intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184 intact:EBI-394704|uniprotkb:Q6NS89|ensembl:ENSP00000293777 psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym) psi-mi:med11_human(display_long)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:MED11(gene name)|psi-mi:MED11(display_short)|uniprotkb:HSPC296(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480704|imex:IM-26985-335 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 refseq:NP_001291929.1|refseq:NP_001001683.1|ensembl:ENSG00000161920(gene)|ensembl:ENST00000293777(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019404|mint:Q9P086|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|go:"GO:0003712"(transcription coregulator activity) - - comment:"author score: 117" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606 rogid:y7SZi5hIo5aOatJSZi98Hqt082A9606 rigid:y+DgNPAjId00fa990t/7jp7XPoU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BUE0 uniprotkb:O75586 intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184 intact:EBI-394624|uniprotkb:Q6FHQ4|uniprotkb:Q9BTH1|uniprotkb:Q9UHL1|uniprotkb:O15401|uniprotkb:Q53FE3|uniprotkb:Q53HJ3|uniprotkb:B4DU17|uniprotkb:B4E2P0|ensembl:ENSP00000256379 psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym) psi-mi:med6_human(display_long)|uniprotkb:ARC33(gene name synonym)|uniprotkb:MED6(gene name)|psi-mi:MED6(display_short)|uniprotkb:Mediator complex subunit 6(gene name synonym)|uniprotkb:Activator-recruited cofactor 33 kDa component(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-28(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480704|imex:IM-26985-335 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 refseq:NP_005457.2|refseq:NP_001271138.1|refseq:NP_001271139.1|refseq:NP_001271140.1|ensembl:ENSG00000133997(gene)|ensembl:ENST00000256379(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR007018(MED6 mediator)|interpro:IPR016820(Mediator complex, subunit 6, metazoa/plant)|interpro:IPR038566|mint:O75586|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31456N - - comment:"author score: 119" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606 rogid:QYK+2tX/HC1OGGPu3b3S1v/ODR89606 rigid:y+DgNPAjId00fa990t/7jp7XPoU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BUE0 uniprotkb:Q6P2C8 intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184 intact:EBI-394603|uniprotkb:Q4F964|uniprotkb:O95401|uniprotkb:Q5VTA4|uniprotkb:Q5VTA5|uniprotkb:Q9BU57|uniprotkb:Q9NYR4|uniprotkb:V9GYV9|ensembl:ENSP00000292035 psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym) psi-mi:med27_human(display_long)|uniprotkb:MED27(gene name)|psi-mi:MED27(display_short)|uniprotkb:Mediator complex subunit 27(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 8(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP34(gene name synonym)|uniprotkb:P37 TRAP/SMCC/PC2 subunit(gene name synonym)|uniprotkb:CRSP34(gene name synonym)|uniprotkb:CRSP8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480704|imex:IM-26985-335 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 refseq:NP_001240811.1|refseq:NP_004260.2|refseq:NP_001240810.1|dip:DIP-31465N|ensembl:ENSG00000160563(gene)|ensembl:ENST00000292035(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021627|mint:Q6P2C8|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 - - comment:"author score: 125" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606 rogid:V1clNhbtflCzCkC7OnaHGYrmQp89606 rigid:y+DgNPAjId00fa990t/7jp7XPoU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13503 uniprotkb:Q5T9A4 intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892 intact:EBI-1384144|uniprotkb:Q6ZRB5|uniprotkb:Q9BUK4|uniprotkb:Q9ULE7|uniprotkb:A8K3H1|ensembl:ENSP00000500094 psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym) psi-mi:atd3b_human(display_long)|uniprotkb:TOB3(gene name synonym)|uniprotkb:AAA-TOB3(gene name synonym)|uniprotkb:KIAA1273(gene name synonym)|uniprotkb:ATAD3B(gene name)|psi-mi:ATAD3B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480797|imex:IM-26985-251 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N refseq:NP_114127.3|refseq:NP_001304167.1|ensembl:ENSG00000160072(gene)|ensembl:ENST00000673477(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR021911|interpro:IPR027417|interpro:IPR039188|mint:Q5T9A4|reactome:R-HSA-6798695 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606 rogid:2W52iPQhTBU2apShm8xhfenV1mU9606 rigid:1n3Z7k1EGmd6fLj18h2kXtW1Z7E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13503 uniprotkb:Q9ULK4 intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892 intact:EBI-311161|uniprotkb:Q5JWT3|uniprotkb:Q5JWT4|uniprotkb:Q6P9H6|uniprotkb:O95403|uniprotkb:Q9H0J2|uniprotkb:Q9NTT9|uniprotkb:Q9NTU0|uniprotkb:Q9Y5P7|uniprotkb:Q9Y667|ensembl:ENSP00000357047|uniprotkb:B9TX55 psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym) psi-mi:med23_human(display_long)|uniprotkb:MED23(gene name)|psi-mi:MED23(display_short)|uniprotkb:ARC130(gene name synonym)|uniprotkb:DRIP130(gene name synonym)|uniprotkb:KIAA1216(gene name synonym)|uniprotkb:SUR2(gene name synonym)|uniprotkb:CRSP3(gene name synonym)|uniprotkb:Mediator complex subunit 23(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 3(gene name synonym)|uniprotkb:Protein sur-2 homolog(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP130(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 130 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 130 kDa component(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480797|imex:IM-26985-251 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N refseq:NP_057063.2|refseq:NP_004821.2|ensembl:ENSG00000112282(gene)|ensembl:ENST00000368068(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016592"(mediator complex)|interpro:IPR021629|mint:Q9ULK4|rcsb pdb:6H02|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001257450.1|refseq:NP_001257451.1|dip:DIP-31461N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606 rogid:gO5TvUnko3zY/83OHbeVmh7b+f89606 rigid:1n3Z7k1EGmd6fLj18h2kXtW1Z7E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13503 uniprotkb:P02655 intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892 intact:EBI-1223594|uniprotkb:Q9BS39|uniprotkb:Q9UDE3|uniprotkb:Q9UNK3|uniprotkb:C0JYY4|ensembl:ENSP00000466775|ensembl:ENSP00000252490 psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym) psi-mi:apoc2_human(display_long)|uniprotkb:APOC2(gene name)|psi-mi:APOC2(display_short)|uniprotkb:APC2(gene name synonym)|uniprotkb:Apolipoprotein C2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480797|imex:IM-26985-251 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N refseq:NP_000474.2|ensembl:ENST00000252490(transcript)|ensembl:ENST00000590360(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005769"(early endosome)|go:"GO:0008289"(lipid binding)|go:"GO:0010518"(positive regulation of phospholipase activity)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0010902"(positive regulation of very-low-density lipoprotein particle remodeling)|go:"GO:0010916"(negative regulation of very-low-density lipoprotein particle clearance)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0032375"(negative regulation of cholesterol transport)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034363"(intermediate-density lipoprotein particle)|go:"GO:0034366"(spherical high-density lipoprotein particle)|go:"GO:0034370"(triglyceride-rich lipoprotein particle remodeling)|go:"GO:0034371"(chylomicron remodeling)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034382"(chylomicron remnant clearance)|go:"GO:0034384"(high-density lipoprotein particle clearance)|go:"GO:0042627"(chylomicron)|ensembl:ENSG00000234906(gene)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0045833"(negative regulation of lipid metabolic process)|go:"GO:0048261"(negative regulation of receptor-mediated endocytosis)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0055102"(lipase inhibitor activity)|go:"GO:0060230"(lipoprotein lipase activator activity)|go:"GO:0060697"(positive regulation of phospholipid catabolic process)|go:"GO:0070328"(triglyceride homeostasis)|interpro:IPR008019(Apolipoprotein C-II)|interpro:IPR023121|mint:P02655|rcsb pdb:1BY6|rcsb pdb:1I5J|rcsb pdb:1O8T|rcsb pdb:1SOH|reactome:R-HSA-8963888|reactome:R-HSA-8963889|reactome:R-HSA-8963901|reactome:R-HSA-8964058|reactome:R-HSA-9029569|reactome:R-HSA-975634 - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606 rogid:kuZbXiBCiqNW+LkINdKZODnrgho9606 rigid:1n3Z7k1EGmd6fLj18h2kXtW1Z7E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13503 uniprotkb:Q9Y2X0 intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892 intact:EBI-394541|uniprotkb:Q6PJT2|uniprotkb:Q96AD4|uniprotkb:Q96I35|uniprotkb:Q9Y652|ensembl:ENSP00000325612 psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym) psi-mi:med16_human(display_long)|uniprotkb:MED16(gene name)|psi-mi:MED16(display_short)|uniprotkb:Mediator complex subunit 16(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 95 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 5(gene name synonym)|uniprotkb:DRIP92(gene name synonym)|uniprotkb:THRAP5(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 92 kDa component(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480797|imex:IM-26985-251 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N refseq:NP_005472.2|ensembl:ENSG00000175221(gene)|ensembl:ENST00000325464(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR001680(WD40 repeat)|interpro:IPR011041(Soluble quinoprotein glucose dehydrogenase)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR021665|interpro:IPR036322|mint:Q9Y2X0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31463N - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606 rogid:nMHDmIPhzAalahGVVsO++rpQE/U9606 rigid:1n3Z7k1EGmd6fLj18h2kXtW1Z7E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13503 uniprotkb:Q86YW9 intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892 intact:EBI-3957138|uniprotkb:Q96PC7|uniprotkb:Q96PC8|uniprotkb:Q9H9M5|uniprotkb:Q9HCD7|uniprotkb:Q9UI69|ensembl:ENSP00000417235 psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym) psi-mi:md12l_human(display_long)|uniprotkb:MED12L(gene name)|psi-mi:MED12L(display_short)|uniprotkb:KIAA1635(gene name synonym)|uniprotkb:TNRC11L(gene name synonym)|uniprotkb:TRALP(gene name synonym)|uniprotkb:TRALPUSH(gene name synonym)|uniprotkb:Mediator complex subunit 12-like protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated-like protein(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 11 protein-like(gene name synonym)|uniprotkb:PRO0314(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480797|imex:IM-26985-251 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N refseq:XP_011510692.1|refseq:NP_443728.3|ensembl:ENST00000309237|ensembl:ENSP00000310760|ensembl:ENST00000422248|ensembl:ENSP00000403308|ensembl:ENSP00000417235|ensembl:ENSG00000144893(gene)|ensembl:ENST00000474524(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016592"(mediator complex)|interpro:IPR019035|interpro:IPR021989|interpro:IPR021990|mint:Q86YW9 - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606 rogid:85LCBTAduFNnKfHO0S10ocwWXyE9606 rigid:1n3Z7k1EGmd6fLj18h2kXtW1Z7E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13503 uniprotkb:Q709F0 intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892 intact:EBI-2880718|ensembl:ENSP00000264990|uniprotkb:Q8WUT6|uniprotkb:Q08AF0|uniprotkb:Q658Y2|uniprotkb:Q658N9|uniprotkb:Q6ZND2|uniprotkb:Q9H9R3 psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym) psi-mi:acd11_human(display_long)|uniprotkb:ACAD11(gene name)|psi-mi:ACAD11(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480797|imex:IM-26985-251 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N ensembl:ENSG00000240303(gene)|ensembl:ENST00000264990(transcript)|go:"GO:0003995"(acyl-CoA dehydrogenase activity)|go:"GO:0004466"(long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR002575(Aminoglycoside phosphotransferase)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|interpro:IPR041726|mint:Q709F0|rcsb pdb:2WBI|reactome:R-HSA-77289|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|refseq:NP_115545.3 - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606 rogid:Qknz1ZNcvX0q/3f5TuGQkJ6oHSk9606 rigid:1n3Z7k1EGmd6fLj18h2kXtW1Z7E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13503 uniprotkb:O75448 intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892 intact:EBI-394523|uniprotkb:Q14143|uniprotkb:Q9NNY5|uniprotkb:A8K4S5|uniprotkb:B3KMR9|ensembl:ENSP00000377686 psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym) psi-mi:med24_human(display_long)|uniprotkb:TRAP100(gene name synonym)|uniprotkb:MED24(gene name)|psi-mi:MED24(display_short)|uniprotkb:DRIP100(gene name synonym)|uniprotkb:KIAA0130(gene name synonym)|uniprotkb:Mediator complex subunit 24(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 100 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 100 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 100 kDa component(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 4(gene name synonym)|uniprotkb:ARC100(gene name synonym)|uniprotkb:CRSP4(gene name synonym)|uniprotkb:THRAP4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480797|imex:IM-26985-251 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N refseq:XP_016880955.1|refseq:NP_001072986.1|refseq:NP_055630.2|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021429|mint:O75448|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000008838(gene)|ensembl:ENST00000394128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|refseq:NP_001254726.1|dip:DIP-31462N - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606 rogid:H0iGOXcj8Qe1FOU7pOXkhaAS+pc9606 rigid:1n3Z7k1EGmd6fLj18h2kXtW1Z7E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13503 uniprotkb:Q96RN5 intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892 intact:EBI-394506|uniprotkb:O15413|uniprotkb:Q6IC31|uniprotkb:Q8NF16|uniprotkb:Q96CT0|uniprotkb:Q96IH7|uniprotkb:Q9P1T3|uniprotkb:D3DX31|uniprotkb:D3DX32|ensembl:ENSP00000263205 psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym) psi-mi:med15_human(display_long)|uniprotkb:MED15(gene name)|psi-mi:MED15(display_short)|uniprotkb:ARC105(gene name synonym)|uniprotkb:CTG7A(gene name synonym)|uniprotkb:Mediator complex subunit 15(gene name synonym)|uniprotkb:Positive cofactor 2 glutamine/Q-rich-associated protein(gene name synonym)|uniprotkb:TPA-inducible gene 1 protein(gene name synonym)|uniprotkb:Activator-recruited cofactor 105 kDa component(gene name synonym)|uniprotkb:CTG repeat protein 7a(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 7 protein(gene name synonym)|uniprotkb:TIG1(gene name synonym)|uniprotkb:PCQAP(gene name synonym)|uniprotkb:TNRC7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480797|imex:IM-26985-251 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N refseq:NP_001280164.1|refseq:NP_001280165.1|refseq:NP_001003891.1|refseq:NP_056973.2|ensembl:ENSG00000099917(gene)|ensembl:ENST00000263205(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|interpro:IPR019087|interpro:IPR036529|mint:Q96RN5|rcsb pdb:2GUT|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-32908N - - comment:"author score: 28" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606 rogid:8dqqSCXYc7Bp56sjogz0jpbTQLI9606 rigid:1n3Z7k1EGmd6fLj18h2kXtW1Z7E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13503 uniprotkb:P02652 intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892 intact:EBI-1171525|uniprotkb:B2R524|ensembl:ENSP00000356969 psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym) psi-mi:apoa2_human(display_long)|uniprotkb:APOA2(gene name)|psi-mi:APOA2(display_short)|uniprotkb:Apolipoprotein A2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480797|imex:IM-26985-251 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N refseq:NP_001634.1|ensembl:ENSG00000158874(gene)|ensembl:ENST00000367990(transcript)|go:"GO:0002526"(acute inflammatory response)|go:"GO:0002719"(negative regulation of cytokine production involved in immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0008289"(lipid binding)|go:"GO:0009395"(phospholipid catabolic process)|go:"GO:0009749"(response to glucose)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010903"(negative regulation of very-low-density lipoprotein particle remodeling)|go:"GO:0015485"(cholesterol binding)|go:"GO:0018158"(protein oxidation)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0018206"(peptidyl-methionine modification)|go:"GO:0030300"(regulation of intestinal cholesterol absorption)|go:"GO:0030301"(cholesterol transport)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032375"(negative regulation of cholesterol transport)|go:"GO:0005576"(extracellular region)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034190"(apolipoprotein receptor binding)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0005829"(cytosol)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0034366"(spherical high-density lipoprotein particle)|go:"GO:0034370"(triglyceride-rich lipoprotein particle remodeling)|go:"GO:0034374"(low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034384"(high-density lipoprotein particle clearance)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042493"|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043627"(response to estrogen)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0046340"(diacylglycerol catabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050821"(protein stabilization)|go:"GO:0050995"(negative regulation of lipid catabolic process)|go:"GO:0050996"(positive regulation of lipid catabolic process)|go:"GO:0051384"(response to glucocorticoid)|go:"GO:0055102"(lipase inhibitor activity)|go:"GO:0060192"(negative regulation of lipase activity)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0060621"(negative regulation of cholesterol import)|go:"GO:0060695"(negative regulation of cholesterol transporter activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070653"(high-density lipoprotein particle receptor binding)|go:"GO:0072562"(blood microparticle)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR006801("Apolipoprotein A-II (ApoA-II)")|interpro:IPR036172|mint:P02652|reactome:R-HSA-1989781|reactome:R-HSA-381426|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-8963901|reactome:R-HSA-975634 - - comment:"author score: 31" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606 rogid:uTkwkAwBXAMjDt6PkLhEazATi4g9606 rigid:1n3Z7k1EGmd6fLj18h2kXtW1Z7E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13503 uniprotkb:Q9NX70 intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892 intact:EBI-394656|uniprotkb:Q9NTF4|uniprotkb:Q5XX09|uniprotkb:B4DNQ6|uniprotkb:M0R2E4|ensembl:ENSP00000314343 psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym) psi-mi:med29_human(display_long)|uniprotkb:MED29(gene name)|psi-mi:MED29(display_short)|uniprotkb:Mediator complex subunit 29(gene name synonym)|uniprotkb:Intersex-like protein(gene name synonym)|uniprotkb:IXL(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480797|imex:IM-26985-251 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N refseq:NP_060062.1|refseq:NP_001304699.1|ensembl:ENSG00000063322(gene)|ensembl:ENST00000315588(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR021018|mint:Q9NX70|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-381340 - - comment:"author score: 35" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606 rogid:WOrt3DAoOape6p0CwWSLIW55hVg9606 rigid:1n3Z7k1EGmd6fLj18h2kXtW1Z7E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13503 uniprotkb:P49336 intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892 intact:EBI-394377|uniprotkb:Q5VUF3|uniprotkb:Q6ISB5|ensembl:ENSP00000370938 psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym) psi-mi:cdk8_human(display_long)|uniprotkb:CDK8(gene name)|psi-mi:CDK8(display_short)|uniprotkb:Cell division protein kinase 8(gene name synonym)|uniprotkb:Mediator of RNA polymerase II transcription subunit CDK8(gene name synonym)|uniprotkb:Mediator complex subunit CDK8(gene name synonym)|uniprotkb:Protein kinase K35(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480797|imex:IM-26985-251 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N refseq:NP_001305297.1|refseq:NP_001251.1|ensembl:ENSG00000132964(gene)|ensembl:ENST00000381527(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006468"(protein phosphorylation)|rcsb pdb:5FGK|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0016592"(mediator complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P49336|rcsb pdb:3RGF|rcsb pdb:4CRL|rcsb pdb:4F6S|rcsb pdb:4F6U|rcsb pdb:4F6W|rcsb pdb:4F70|rcsb pdb:4F7J|rcsb pdb:4F7L|rcsb pdb:4F7N|rcsb pdb:4F7S|rcsb pdb:4G6L|rcsb pdb:5BNJ|rcsb pdb:5CEI|rcsb pdb:5HBE|rcsb pdb:5HBH|rcsb pdb:5HBJ|rcsb pdb:5HNB|rcsb pdb:5HVY|rcsb pdb:5I5Z|rcsb pdb:5ICP|rcsb pdb:5IDN|rcsb pdb:5IDP|rcsb pdb:5XQX|rcsb pdb:5XS2|rcsb pdb:6QTG|rcsb pdb:6QTJ|rcsb pdb:6R3S|rcsb pdb:6T41|rcsb pdb:6TPA|rcsb pdb:6Y0A|reactome:R-HSA-1989781|reactome:R-HSA-2122947|reactome:R-HSA-212436|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-381340|dip:DIP-32595N - - comment:"author score: 43" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606 rogid:f+78iyCfA9osCQ82uY6reu3JKzo9606 rigid:1n3Z7k1EGmd6fLj18h2kXtW1Z7E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13503 uniprotkb:Q9BWU1 intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892 intact:EBI-394593|uniprotkb:Q5JQZ7|uniprotkb:Q5JR00|uniprotkb:Q8TC78|uniprotkb:Q9UPX2|intact:EBI-28987871|ensembl:ENSP00000357907 psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym) psi-mi:cdk19_human(display_long)|uniprotkb:CDK19(gene name)|psi-mi:CDK19(display_short)|uniprotkb:CDC2-related protein kinase 6(gene name synonym)|uniprotkb:Death-preventing kinase(gene name synonym)|uniprotkb:Cyclin-dependent kinase 11(gene name synonym)|uniprotkb:CDK11(gene name synonym)|uniprotkb:KIAA1028(gene name synonym)|uniprotkb:CDC2L6(gene name synonym)|uniprotkb:Cell division cycle 2-like protein kinase 6(gene name synonym)|uniprotkb:Cell division protein kinase 19(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480797|imex:IM-26985-251 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N refseq:NP_055891.1|refseq:NP_001287889.1|refseq:NP_001287892.1|refseq:NP_001287893.1|ensembl:ENSG00000155111(gene)|ensembl:ENST00000368911(transcript)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0016592"(mediator complex)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q9BWU1|reactome:R-HSA-1989781|reactome:R-HSA-381340|ensembl:ENST00000323817|ensembl:ENSP00000317665|ensembl:ENSP00000357907|dip:DIP-29013N - - comment:"author score: 44" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606 rogid:80Ngzl9uqRnqMjGnO5v7j72eY7E9606 rigid:1n3Z7k1EGmd6fLj18h2kXtW1Z7E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13503 uniprotkb:P24863 intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892 intact:EBI-395261|uniprotkb:Q9H543|ensembl:ENSP00000428982|uniprotkb:B4DPZ1 psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym) psi-mi:ccnc_human(display_long)|uniprotkb:CCNC(gene name)|psi-mi:CCNC(display_short)|uniprotkb:SRB11 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480797|imex:IM-26985-251 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N ensembl:ENSG00000112237(gene)|ensembl:ENST00000520429(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR028367|interpro:IPR036915|interpro:IPR043198|mint:P24863|rcsb pdb:5XQX|rcsb pdb:5XS2|rcsb pdb:6QTG|rcsb pdb:6QTJ|rcsb pdb:6R3S|rcsb pdb:6T41|rcsb pdb:6TPA|rcsb pdb:6Y0A|reactome:R-HSA-1989781|reactome:R-HSA-2122947|reactome:R-HSA-212436|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-381340|rcsb pdb:3RGF|rcsb pdb:4CRL|rcsb pdb:4F6S|rcsb pdb:4F6U|rcsb pdb:4F6W|rcsb pdb:4F70|rcsb pdb:4F7J|rcsb pdb:4F7L|rcsb pdb:4F7N|rcsb pdb:4F7S|rcsb pdb:4G6L|rcsb pdb:5BNJ|rcsb pdb:5CEI|rcsb pdb:5FGK|rcsb pdb:5HBE|rcsb pdb:5HBH|rcsb pdb:5HBJ|rcsb pdb:5HNB|rcsb pdb:5HVY|rcsb pdb:5I5Z|rcsb pdb:5ICP|rcsb pdb:5IDN|rcsb pdb:5IDP|refseq:NP_005181.2|refseq:NP_001013417.1|dip:DIP-32920N - - comment:"author score: 46" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606 rogid:Gu327q98H8ggQoYCb4UnR2Mcsyg9606 rigid:1n3Z7k1EGmd6fLj18h2kXtW1Z7E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13503 uniprotkb:Q9UHV7 intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892 intact:EBI-394440|uniprotkb:O60334|uniprotkb:B2RU05|ensembl:ENSP00000380888 psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym) psi-mi:med13_human(display_long)|uniprotkb:TRAP240(gene name synonym)|uniprotkb:MED13(gene name)|psi-mi:MED13(display_short)|uniprotkb:ARC250(gene name synonym)|uniprotkb:KIAA0593(gene name synonym)|uniprotkb:Mediator complex subunit 13(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 240 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 1(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex component DRIP250(gene name synonym)|uniprotkb:Activator-recruited cofactor 250 kDa component(gene name synonym)|uniprotkb:THRAP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480797|imex:IM-26985-251 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N refseq:NP_005112.2|ensembl:ENSG00000108510(gene)|ensembl:ENST00000397786(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR009401(TRAP240)|interpro:IPR041285|mint:Q9UHV7|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31468N - - comment:"author score: 49" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606 rogid:ZNWwmsetsKLA56joRzRL0UKjq9Y9606 rigid:1n3Z7k1EGmd6fLj18h2kXtW1Z7E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13503 uniprotkb:Q71F56 intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892 intact:EBI-394435|uniprotkb:A1L469|uniprotkb:Q68DN4|uniprotkb:Q9H8C0|uniprotkb:Q9NSY9|uniprotkb:Q9UFD8|uniprotkb:Q9UPX5|ensembl:ENSP00000281928 psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym) psi-mi:md13l_human(display_long)|uniprotkb:Mediator complex subunit 13-like(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 2(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 240 kDa component-like(gene name synonym)|uniprotkb:MED13L(gene name)|psi-mi:MED13L(display_short)|uniprotkb:KIAA1025(gene name synonym)|uniprotkb:PROSIT240(gene name synonym)|uniprotkb:THRAP2(gene name synonym)|uniprotkb:TRAP240L(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480797|imex:IM-26985-251 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N refseq:NP_056150.1|ensembl:ENSG00000123066(gene)|ensembl:ENST00000281928(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR009401(TRAP240)|interpro:IPR021643|interpro:IPR041285|mint:Q71F56|reactome:R-HSA-1989781|reactome:R-HSA-381340 - - comment:"author score: 71" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606 rogid:Zdj5dM/HEWW8zS27yaXsR+ZOxZs9606 rigid:1n3Z7k1EGmd6fLj18h2kXtW1Z7E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13503 uniprotkb:Q93074 intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892 intact:EBI-394357|uniprotkb:O15410|uniprotkb:O75557|uniprotkb:Q9UHV6|uniprotkb:Q9UND7|ensembl:ENSP00000363193 psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym) psi-mi:med12_human(display_long)|uniprotkb:TRAP230(gene name synonym)|uniprotkb:MED12(gene name)|psi-mi:MED12(display_short)|uniprotkb:ARC240(gene name synonym)|uniprotkb:CAGH45(gene name synonym)|uniprotkb:HOPA(gene name synonym)|uniprotkb:KIAA0192(gene name synonym)|uniprotkb:Mediator complex subunit 12(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 230 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 240 kDa component(gene name synonym)|uniprotkb:CAG repeat protein 45(gene name synonym)|uniprotkb:OPA-containing protein(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 11 protein(gene name synonym)|uniprotkb:TNRC11(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480797|imex:IM-26985-251 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N refseq:NP_005111.2|ensembl:ENSG00000184634(gene)|ensembl:ENST00000374080(transcript)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0090245"(axis elongation involved in somitogenesis)|go:"GO:1990403"(embryonic brain development)|interpro:IPR019035|interpro:IPR021989|interpro:IPR021990|mint:Q93074|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0014044"(Schwann cell development)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|dip:DIP-31459N - - comment:"author score: 91" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606 rogid:soNqTi3/n+qnj+P4AX/cPJzTK2U9606 rigid:1n3Z7k1EGmd6fLj18h2kXtW1Z7E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13503 uniprotkb:Q15528 intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892 intact:EBI-394687|uniprotkb:Q5T8U0|uniprotkb:O76072|uniprotkb:B3KW83|uniprotkb:B3KWX4|ensembl:ENSP00000342343|ensembl:ENSP00000482438|ensembl:ENSP00000485880|ensembl:ENSP00000487580 psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym) psi-mi:med22_human(display_long)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:MED22(gene name)|psi-mi:MED22(display_short)|uniprotkb:Surfeit locus protein 5(gene name synonym)|uniprotkb:SURF5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480797|imex:IM-26985-251 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N refseq:NP_598395.1|refseq:NP_852468.1|ensembl:ENSG00000148297(gene)|ensembl:ENSG00000281022(gene)|ensembl:ENST00000343730(transcript)|ensembl:ENST00000610672(transcript)|ensembl:ENST00000629522(transcript)|ensembl:ENST00000631196(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR009332(Surfeit locus 5)|mint:Q15528|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 - - comment:"author score: 96" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606 rogid:bAtK0Srk81ujvVt2Gj0+py7RCZY9606 rigid:1n3Z7k1EGmd6fLj18h2kXtW1Z7E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13503 uniprotkb:Q9BUE0 intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892 intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184 psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym) psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480797|imex:IM-26985-251 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 - - comment:"author score: 105" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606 rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606 rigid:1n3Z7k1EGmd6fLj18h2kXtW1Z7E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13503 uniprotkb:Q9P086 intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892 intact:EBI-394704|uniprotkb:Q6NS89|ensembl:ENSP00000293777 psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym) psi-mi:med11_human(display_long)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:MED11(gene name)|psi-mi:MED11(display_short)|uniprotkb:HSPC296(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480797|imex:IM-26985-251 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N refseq:NP_001291929.1|refseq:NP_001001683.1|ensembl:ENSG00000161920(gene)|ensembl:ENST00000293777(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019404|mint:Q9P086|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|go:"GO:0003712"(transcription coregulator activity) - - comment:"author score: 116" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606 rogid:y7SZi5hIo5aOatJSZi98Hqt082A9606 rigid:1n3Z7k1EGmd6fLj18h2kXtW1Z7E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13503 uniprotkb:O95402 intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892 intact:EBI-394392|uniprotkb:A1A4S3|uniprotkb:Q0VGB6|intact:EBI-28974475|ensembl:ENSP00000263390 psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym) psi-mi:med26_human(display_long)|uniprotkb:ARC70(gene name synonym)|uniprotkb:MED26(gene name)|psi-mi:MED26(display_short)|uniprotkb:Mediator complex subunit 26(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 7(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP70(gene name synonym)|uniprotkb:Activator-recruited cofactor 70 kDa component(gene name synonym)|uniprotkb:CRSP7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480797|imex:IM-26985-251 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N ensembl:ENSP00000263390|ensembl:ENST00000611692|ensembl:ENSP00000484490|refseq:NP_004822.2|ensembl:ENSG00000105085(gene)|ensembl:ENST00000263390(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR017923|interpro:IPR031416|interpro:IPR031417|interpro:IPR035441|interpro:IPR042376|mint:O95402|rcsb pdb:5ODD|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31464N - - comment:"author score: 124" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606 rogid:1kRmQ+QH5uQkKVfjo2Rc2SkAyKc9606 rigid:1n3Z7k1EGmd6fLj18h2kXtW1Z7E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13503 uniprotkb:O75586 intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892 intact:EBI-394624|uniprotkb:Q6FHQ4|uniprotkb:Q9BTH1|uniprotkb:Q9UHL1|uniprotkb:O15401|uniprotkb:Q53FE3|uniprotkb:Q53HJ3|uniprotkb:B4DU17|uniprotkb:B4E2P0|ensembl:ENSP00000256379 psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym) psi-mi:med6_human(display_long)|uniprotkb:ARC33(gene name synonym)|uniprotkb:MED6(gene name)|psi-mi:MED6(display_short)|uniprotkb:Mediator complex subunit 6(gene name synonym)|uniprotkb:Activator-recruited cofactor 33 kDa component(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-28(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480797|imex:IM-26985-251 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N refseq:NP_005457.2|refseq:NP_001271138.1|refseq:NP_001271139.1|refseq:NP_001271140.1|ensembl:ENSG00000133997(gene)|ensembl:ENST00000256379(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR007018(MED6 mediator)|interpro:IPR016820(Mediator complex, subunit 6, metazoa/plant)|interpro:IPR038566|mint:O75586|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31456N - - comment:"author score: 150" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606 rogid:QYK+2tX/HC1OGGPu3b3S1v/ODR89606 rigid:1n3Z7k1EGmd6fLj18h2kXtW1Z7E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13503 uniprotkb:Q96HR3 intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892 intact:EBI-394659|uniprotkb:C6GKU9|intact:EBI-11137618|ensembl:ENSP00000297347 psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym) psi-mi:med30_human(display_long)|uniprotkb:TRAP25(gene name synonym)|uniprotkb:MED30(gene name)|psi-mi:MED30(display_short)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)|uniprotkb:TRAP/Mediator complex component TRAP25(gene name synonym)|uniprotkb:THRAP6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480797|imex:IM-26985-251 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N refseq:NP_542382.1|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|mint:Q96HR3|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001269915.1|ensembl:ENSG00000164758(gene)|ensembl:ENST00000297347(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity) - - comment:"author score: 151" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606 rogid:dUgR7zxbKAcYqPKb8teHBLgUhWY9606 rigid:1n3Z7k1EGmd6fLj18h2kXtW1Z7E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13503 uniprotkb:Q9H944 intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892 intact:EBI-394644|uniprotkb:Q9Y429|uniprotkb:O95821|uniprotkb:Q5T8J4|uniprotkb:B4DE08|ensembl:ENSP00000265350 psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym) psi-mi:med20_human(display_long)|uniprotkb:TRFP(gene name synonym)|uniprotkb:MED20(gene name)|psi-mi:MED20(display_short)|uniprotkb:Mediator complex subunit 20(gene name synonym)|uniprotkb:TRF-proximal protein homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480797|imex:IM-26985-251 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N refseq:NP_004266.2|refseq:NP_001292384.1|refseq:NP_001292385.1|refseq:NP_001292386.1|go:"GO:0016592"(mediator complex)|interpro:IPR013921(TATA-binding related factor)|mint:Q9H944|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000124641(gene)|ensembl:ENST00000265350(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|dip:DIP-31449N - - comment:"author score: 157" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606 rogid:MpYOrONH6+0lKIlO6J+Szjzkw2A9606 rigid:1n3Z7k1EGmd6fLj18h2kXtW1Z7E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13503 uniprotkb:Q9H204 intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892 intact:EBI-514199|uniprotkb:Q9BZJ5|ensembl:ENSP00000237380 psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym) psi-mi:med28_human(display_long)|uniprotkb:Mediator complex subunit 28(gene name synonym)|uniprotkb:Tumor angiogenesis marker EG-1(gene name synonym)|uniprotkb:Endothelial-derived protein 1(gene name synonym)|uniprotkb:Merlin and Grb2-interacting cytoskeletal protein(gene name synonym)|uniprotkb:MED28(gene name)|psi-mi:MED28(display_short)|uniprotkb:EG1(gene name synonym)|uniprotkb:FKSG20(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480797|imex:IM-26985-251 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N refseq:NP_079481.2|ensembl:ENSG00000118579(gene)|ensembl:ENST00000237380(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0051151"(negative regulation of smooth muscle cell differentiation)|interpro:IPR021640|mint:Q9H204|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 - - comment:"author score: 158" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606 rogid:1gt/0vP7vWJ+M1fU+qZPcWGj34U9606 rigid:1n3Z7k1EGmd6fLj18h2kXtW1Z7E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13503 uniprotkb:Q6P2C8 intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892 intact:EBI-394603|uniprotkb:Q4F964|uniprotkb:O95401|uniprotkb:Q5VTA4|uniprotkb:Q5VTA5|uniprotkb:Q9BU57|uniprotkb:Q9NYR4|uniprotkb:V9GYV9|ensembl:ENSP00000292035 psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym) psi-mi:med27_human(display_long)|uniprotkb:MED27(gene name)|psi-mi:MED27(display_short)|uniprotkb:Mediator complex subunit 27(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 8(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP34(gene name synonym)|uniprotkb:P37 TRAP/SMCC/PC2 subunit(gene name synonym)|uniprotkb:CRSP34(gene name synonym)|uniprotkb:CRSP8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480797|imex:IM-26985-251 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N refseq:NP_001240811.1|refseq:NP_004260.2|refseq:NP_001240810.1|dip:DIP-31465N|ensembl:ENSG00000160563(gene)|ensembl:ENST00000292035(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021627|mint:Q6P2C8|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 - - comment:"author score: 161" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606 rogid:V1clNhbtflCzCkC7OnaHGYrmQp89606 rigid:1n3Z7k1EGmd6fLj18h2kXtW1Z7E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13503 uniprotkb:Q96G25 intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892 intact:EBI-394405|uniprotkb:A9IZ91|uniprotkb:Q96FQ4|uniprotkb:A9IZ92|uniprotkb:Q5JUY8|ensembl:ENSP00000361535 psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym) psi-mi:med8_human(display_long)|uniprotkb:MED8(gene name)|psi-mi:MED8(display_short)|uniprotkb:Mediator complex subunit 8(gene name synonym)|uniprotkb:Activator-recruited cofactor 32 kDa component(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480797|imex:IM-26985-251 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N refseq:NP_443109.2|refseq:NP_963836.2|refseq:NP_001001653.1|ensembl:ENSG00000159479(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|mint:Q96G25|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENST00000372457(transcript) - - comment:"author score: 162" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606 rogid:e/ye7rfa2E1XOPb5vVhI9Nvqmxw9606 rigid:1n3Z7k1EGmd6fLj18h2kXtW1Z7E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13503 uniprotkb:Q9NVC6 intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892 intact:EBI-394562|uniprotkb:Q9HA81|uniprotkb:Q9UNP7|uniprotkb:Q9Y2W0|uniprotkb:Q9Y660|uniprotkb:B3KN07|ensembl:ENSP00000251871 psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym) psi-mi:med17_human(display_long)|uniprotkb:TRAP80(gene name synonym)|uniprotkb:MED17(gene name)|psi-mi:MED17(display_short)|uniprotkb:ARC77(gene name synonym)|uniprotkb:DRIP80(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 6(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP77(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 80 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 80 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 77 kDa component(gene name synonym)|uniprotkb:CRSP6(gene name synonym)|uniprotkb:DRIP77(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480797|imex:IM-26985-251 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N refseq:NP_004259.3|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|ensembl:ENSG00000042429(gene)|ensembl:ENST00000251871(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019313|mint:Q9NVC6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31451N - - comment:"author score: 166" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606 rogid:P2hRQOjWEtjw5V+lt7J9TP3VbpU9606 rigid:1n3Z7k1EGmd6fLj18h2kXtW1Z7E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13503 uniprotkb:Q9NWA0 intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892 intact:EBI-394653|ensembl:ENSP00000268711 psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym) psi-mi:med9_human(display_long)|uniprotkb:MED9(gene name)|psi-mi:MED9(display_short)|uniprotkb:Mediator complex subunit 9(gene name synonym)|uniprotkb:MED25(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480797|imex:IM-26985-251 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N refseq:NP_060489.1|ensembl:ENSG00000141026(gene)|ensembl:ENST00000268711(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR011425(RNA polymerase II transcription mediator)|interpro:IPR037212|interpro:IPR039242|mint:Q9NWA0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 - - comment:"author score: 180" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606 rogid:VSYpA1Aqh2FEaZIEF/6iCIpoPEc9606 rigid:1n3Z7k1EGmd6fLj18h2kXtW1Z7E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13503 uniprotkb:Q15648 intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892 intact:EBI-394459|uniprotkb:A2RRQ6|uniprotkb:O43810|uniprotkb:O75447|uniprotkb:Q6P9H7|uniprotkb:Q6PK58|uniprotkb:Q9HD39|ensembl:ENSP00000300651 psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym) psi-mi:med1_human(display_long)|uniprotkb:TRIP2(gene name synonym)|uniprotkb:MED1(gene name)|psi-mi:MED1(display_short)|uniprotkb:ARC205(gene name synonym)|uniprotkb:DRIP205(gene name synonym)|uniprotkb:TRAP220(gene name synonym)|uniprotkb:Activator-recruited cofactor 205 kDa component(gene name synonym)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-binding protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 220 kDa component(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 2(gene name synonym)|uniprotkb:p53 regulatory protein RB18A(gene name synonym)|uniprotkb:Vitamin D receptor-interacting protein complex component DRIP205(gene name synonym)|uniprotkb:CRSP1(gene name synonym)|uniprotkb:CRSP200(gene name synonym)|uniprotkb:DRIP230(gene name synonym)|uniprotkb:PBP(gene name synonym)|uniprotkb:PPARBP(gene name synonym)|uniprotkb:PPARGBP(gene name synonym)|uniprotkb:RB18A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480797|imex:IM-26985-251 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N refseq:NP_004765.2|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR019680|mint:Q15648|rcsb pdb:1RJK|rcsb pdb:1RK3|rcsb pdb:1RKG|rcsb pdb:1RKH|rcsb pdb:2O4J|rcsb pdb:2O4R|rcsb pdb:2ZFX|rcsb pdb:3A2H|rcsb pdb:3AUN|rcsb pdb:3VJS|rcsb pdb:3VJT|rcsb pdb:3VRT|rcsb pdb:3VRU|rcsb pdb:3VRV|rcsb pdb:3VRW|rcsb pdb:3W0G|rcsb pdb:3W0H|rcsb pdb:3W0I|rcsb pdb:3W0J|rcsb pdb:3W5P|rcsb pdb:3W5Q|rcsb pdb:3W5R|rcsb pdb:3W5T|rcsb pdb:3WT5|rcsb pdb:3WT6|rcsb pdb:3WT7|rcsb pdb:3WTQ|rcsb pdb:4YNK|rcsb pdb:5AWJ|rcsb pdb:5AWK|rcsb pdb:5B41|rcsb pdb:5B5B|rcsb pdb:5GIC|rcsb pdb:5GID|rcsb pdb:5GIE|rcsb pdb:5XPM|rcsb pdb:5XPN|rcsb pdb:5XPO|rcsb pdb:5XPP|rcsb pdb:5XUQ|rcsb pdb:5XZF|rcsb pdb:5XZH|rcsb pdb:5ZWE|rcsb pdb:5ZWF|rcsb pdb:5ZWH|rcsb pdb:5ZWI|rcsb pdb:6D94|rcsb pdb:6JEZ|rcsb pdb:6K5O|rcsb pdb:6ONJ|rcsb pdb:7C7V|rcsb pdb:7C7W|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9707564|reactome:R-HSA-9707616|ensembl:ENSG00000125686(gene)|ensembl:ENST00000300651(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003406"(retinal pigment epithelium development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0050693"(LBD domain binding)|dip:DIP-24212N - - comment:"author score: 181" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606 rogid:A4EIAri9zYycSlTA7s6NzbOi9n49606 rigid:1n3Z7k1EGmd6fLj18h2kXtW1Z7E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13503 uniprotkb:O60244 intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892 intact:EBI-394489|uniprotkb:Q4KMR7|uniprotkb:Q9UNB3|ensembl:ENSP00000323720 psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym) psi-mi:med14_human(display_long)|uniprotkb:TRAP170(gene name synonym)|uniprotkb:MED14(gene name)|psi-mi:MED14(display_short)|uniprotkb:ARC150(gene name synonym)|uniprotkb:DRIP150(gene name synonym)|uniprotkb:EXLM1(gene name synonym)|uniprotkb:RGR1(gene name synonym)|uniprotkb:Mediator complex subunit 14(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 2(gene name synonym)|uniprotkb:RGR1 homolog(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP150(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 150 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 170 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 150 kDa component(gene name synonym)|uniprotkb:CRSP2(gene name synonym)|uniprotkb:CXorf4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480797|imex:IM-26985-251 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N refseq:NP_004220.2|ensembl:ENSG00000180182(gene)|ensembl:ENST00000324817(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR013947(Mediator complex, subunit MED14)|mint:O60244|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31460N - - comment:"author score: 191" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606 rogid:73RBAnwmB4Lyl/kcsg7NKSUmA4c9606 rigid:1n3Z7k1EGmd6fLj18h2kXtW1Z7E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13503 uniprotkb:A0JLT2 intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892 intact:EBI-394430|uniprotkb:Q8IV02|intact:EBI-394763|uniprotkb:Q8IZD1 psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym) psi-mi:med19_human(display_long)|uniprotkb:MED19(gene name)|psi-mi:MED19(display_short)|uniprotkb:LCMR1(gene name synonym)|uniprotkb:Lung cancer metastasis-related protein 1(gene name synonym)|uniprotkb:Mediator complex subunit 19(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480797|imex:IM-26985-251 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N refseq:NP_001304007.1|refseq:NP_703151.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR019403|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|mint:A0JLT2|dip:DIP-31467N - - comment:"author score: 203" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606 rogid:zcHhU2hQvuTpkFZz/xEKYmjrwOA9606 rigid:1n3Z7k1EGmd6fLj18h2kXtW1Z7E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13503 uniprotkb:Q9Y3C7 intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892 intact:EBI-394707|uniprotkb:B2R4L9|ensembl:ENSP00000225728 psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym) psi-mi:med31_human(display_long)|uniprotkb:CGI-125(orf name)|uniprotkb:SOH1(gene name synonym)|uniprotkb:MED31(gene name)|psi-mi:MED31(display_short)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480797|imex:IM-26985-251 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N refseq:NP_057144.1|ensembl:ENSG00000108590(gene)|ensembl:ENST00000225728(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|mint:Q9Y3C7|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 - - comment:"author score: 207" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606 rogid:QRmf6b+uoUOubBcvJbBfl9NgRTQ9606 rigid:1n3Z7k1EGmd6fLj18h2kXtW1Z7E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13503 uniprotkb:Q9BTT4 intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892 intact:EBI-394354|uniprotkb:C6G491|ensembl:ENSP00000255764 psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym) psi-mi:med10_human(display_long)|uniprotkb:MED10(gene name)|psi-mi:MED10(display_short)|uniprotkb:L6(orf name)|uniprotkb:TRG17(orf name)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Transformation-related gene 17 protein(gene name synonym)|uniprotkb:Transformation-related gene 20 protein(gene name synonym)|uniprotkb:TRG20(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480797|imex:IM-26985-251 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N ensembl:ENSG00000133398(gene)|ensembl:ENST00000255764(transcript)|refseq:NP_115662.2|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019145|mint:Q9BTT4|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|go:"GO:0000151"(ubiquitin ligase complex)|dip:DIP-31457N - - comment:"author score: 227" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606 rogid:LzJW7C8kl2pWmffOjo8S/FNSS9I9606 rigid:1n3Z7k1EGmd6fLj18h2kXtW1Z7E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13503 uniprotkb:Q9NPJ6 intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892 intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648 psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym) psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480797|imex:IM-26985-251 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 - - comment:"author score: 237" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606 rogid:Bept2Oec50gruA9e4pf+eEUiANM9606 rigid:1n3Z7k1EGmd6fLj18h2kXtW1Z7E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96HR3 uniprotkb:O75448 intact:EBI-394659|uniprotkb:C6GKU9|intact:EBI-11137618|ensembl:ENSP00000297347 intact:EBI-394523|uniprotkb:Q14143|uniprotkb:Q9NNY5|uniprotkb:A8K4S5|uniprotkb:B3KMR9|ensembl:ENSP00000377686 psi-mi:med30_human(display_long)|uniprotkb:TRAP25(gene name synonym)|uniprotkb:MED30(gene name)|psi-mi:MED30(display_short)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)|uniprotkb:TRAP/Mediator complex component TRAP25(gene name synonym)|uniprotkb:THRAP6(gene name synonym) psi-mi:med24_human(display_long)|uniprotkb:TRAP100(gene name synonym)|uniprotkb:MED24(gene name)|psi-mi:MED24(display_short)|uniprotkb:DRIP100(gene name synonym)|uniprotkb:KIAA0130(gene name synonym)|uniprotkb:Mediator complex subunit 24(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 100 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 100 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 100 kDa component(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 4(gene name synonym)|uniprotkb:ARC100(gene name synonym)|uniprotkb:CRSP4(gene name synonym)|uniprotkb:THRAP4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480905|imex:IM-26985-487 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_542382.1|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|mint:Q96HR3|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001269915.1|ensembl:ENSG00000164758(gene)|ensembl:ENST00000297347(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity) refseq:XP_016880955.1|refseq:NP_001072986.1|refseq:NP_055630.2|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021429|mint:O75448|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000008838(gene)|ensembl:ENST00000394128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|refseq:NP_001254726.1|dip:DIP-31462N - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dUgR7zxbKAcYqPKb8teHBLgUhWY9606 rogid:H0iGOXcj8Qe1FOU7pOXkhaAS+pc9606 rigid:nyMqHiCBy+SHw8GrglvfiFfj2Z4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96HR3 uniprotkb:Q96RN5 intact:EBI-394659|uniprotkb:C6GKU9|intact:EBI-11137618|ensembl:ENSP00000297347 intact:EBI-394506|uniprotkb:O15413|uniprotkb:Q6IC31|uniprotkb:Q8NF16|uniprotkb:Q96CT0|uniprotkb:Q96IH7|uniprotkb:Q9P1T3|uniprotkb:D3DX31|uniprotkb:D3DX32|ensembl:ENSP00000263205 psi-mi:med30_human(display_long)|uniprotkb:TRAP25(gene name synonym)|uniprotkb:MED30(gene name)|psi-mi:MED30(display_short)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)|uniprotkb:TRAP/Mediator complex component TRAP25(gene name synonym)|uniprotkb:THRAP6(gene name synonym) psi-mi:med15_human(display_long)|uniprotkb:MED15(gene name)|psi-mi:MED15(display_short)|uniprotkb:ARC105(gene name synonym)|uniprotkb:CTG7A(gene name synonym)|uniprotkb:Mediator complex subunit 15(gene name synonym)|uniprotkb:Positive cofactor 2 glutamine/Q-rich-associated protein(gene name synonym)|uniprotkb:TPA-inducible gene 1 protein(gene name synonym)|uniprotkb:Activator-recruited cofactor 105 kDa component(gene name synonym)|uniprotkb:CTG repeat protein 7a(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 7 protein(gene name synonym)|uniprotkb:TIG1(gene name synonym)|uniprotkb:PCQAP(gene name synonym)|uniprotkb:TNRC7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480905|imex:IM-26985-487 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_542382.1|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|mint:Q96HR3|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001269915.1|ensembl:ENSG00000164758(gene)|ensembl:ENST00000297347(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_001280164.1|refseq:NP_001280165.1|refseq:NP_001003891.1|refseq:NP_056973.2|ensembl:ENSG00000099917(gene)|ensembl:ENST00000263205(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|interpro:IPR019087|interpro:IPR036529|mint:Q96RN5|rcsb pdb:2GUT|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-32908N - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dUgR7zxbKAcYqPKb8teHBLgUhWY9606 rogid:8dqqSCXYc7Bp56sjogz0jpbTQLI9606 rigid:nyMqHiCBy+SHw8GrglvfiFfj2Z4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96HR3 uniprotkb:P0CAP2 intact:EBI-394659|uniprotkb:C6GKU9|intact:EBI-11137618|ensembl:ENSP00000297347 intact:EBI-9657655|uniprotkb:Q96NF5|uniprotkb:Q6EFN8|uniprotkb:Q6EEV3|uniprotkb:Q9Y3V6|uniprotkb:Q8NC58|uniprotkb:Q96DI5|uniprotkb:Q6EF02|uniprotkb:Q6K050|uniprotkb:Q6K046|uniprotkb:Q6K051|uniprotkb:Q6EF01|uniprotkb:Q6EES2|uniprotkb:Q8NCF3|uniprotkb:Q6EM48|uniprotkb:Q6EF46|uniprotkb:Q6ZQZ3|uniprotkb:Q6EER8|uniprotkb:Q96JB7|uniprotkb:Q6EF00|ensembl:ENSP00000299638 psi-mi:med30_human(display_long)|uniprotkb:TRAP25(gene name synonym)|uniprotkb:MED30(gene name)|psi-mi:MED30(display_short)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)|uniprotkb:TRAP/Mediator complex component TRAP25(gene name synonym)|uniprotkb:THRAP6(gene name synonym) psi-mi:grl1a_human(display_long)|uniprotkb:POLR2M(gene name)|psi-mi:POLR2M(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit M(gene name synonym)|uniprotkb:GRINL1A(gene name synonym)|uniprotkb:Glutamate receptor-like protein 1A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480905|imex:IM-26985-487 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_542382.1|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|mint:Q96HR3|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001269915.1|ensembl:ENSG00000164758(gene)|ensembl:ENST00000297347(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_001018112.1|refseq:NP_056347.1|dip:DIP-61933N|ensembl:ENSG00000255529(gene)|ensembl:ENST00000299638(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051685"(maintenance of ER location)|interpro:IPR026213|mint:P0CAP2|rcsb pdb:6DRD - - comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dUgR7zxbKAcYqPKb8teHBLgUhWY9606 rogid:G0QVxeD0uvJTl0VPn+b3pV6zLe89606 rigid:nyMqHiCBy+SHw8GrglvfiFfj2Z4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96HR3 uniprotkb:Q8IXW5 intact:EBI-394659|uniprotkb:C6GKU9|intact:EBI-11137618|ensembl:ENSP00000297347 intact:EBI-395878|uniprotkb:Q49AS7|uniprotkb:Q9H8Y2|ensembl:ENSP00000476948|uniprotkb:C9JKB5 psi-mi:med30_human(display_long)|uniprotkb:TRAP25(gene name synonym)|uniprotkb:MED30(gene name)|psi-mi:MED30(display_short)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)|uniprotkb:TRAP/Mediator complex component TRAP25(gene name synonym)|uniprotkb:THRAP6(gene name synonym) psi-mi:rpap2_human(display_long)|uniprotkb:RPAP2(gene name)|psi-mi:RPAP2(display_short)|uniprotkb:C1orf82(gene name synonym)|uniprotkb:RNA polymerase II-associated protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480905|imex:IM-26985-487 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_542382.1|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|mint:Q96HR3|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001269915.1|ensembl:ENSG00000164758(gene)|ensembl:ENST00000297347(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_079089.2|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008420"(RNA polymerase II CTD heptapeptide repeat phosphatase activity)|go:"GO:0009301"(snRNA transcription)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0043175"(RNA polymerase core enzyme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR007308(Protein of unknown function DUF408)|interpro:IPR038534|interpro:IPR039693|mint:Q8IXW5|rcsb pdb:7B7U|reactome:R-HSA-6807505|ensembl:ENSG00000122484(gene)|ensembl:ENST00000610020(transcript)|go:"GO:0005634"(nucleus)|dip:DIP-32939N - - comment:"author score: 27" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dUgR7zxbKAcYqPKb8teHBLgUhWY9606 rogid:niEFEvqkASycxkzfe9TYJuerUuY9606 rigid:nyMqHiCBy+SHw8GrglvfiFfj2Z4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96HR3 uniprotkb:P62487 intact:EBI-394659|uniprotkb:C6GKU9|intact:EBI-11137618|ensembl:ENSP00000297347 intact:EBI-347928|ensembl:ENSP00000301788|uniprotkb:P52433|uniprotkb:Q2M1Z4|uniprotkb:B2R5C0 psi-mi:med30_human(display_long)|uniprotkb:TRAP25(gene name synonym)|uniprotkb:MED30(gene name)|psi-mi:MED30(display_short)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)|uniprotkb:TRAP/Mediator complex component TRAP25(gene name synonym)|uniprotkb:THRAP6(gene name synonym) psi-mi:rpb7_human(display_long)|uniprotkb:POLR2G(gene name)|psi-mi:POLR2G(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit G(gene name synonym)|uniprotkb:RPB7(gene name synonym)|uniprotkb:RNA polymerase II 19 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480905|imex:IM-26985-487 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_542382.1|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|mint:Q96HR3|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001269915.1|ensembl:ENSG00000164758(gene)|ensembl:ENST00000297347(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity) ensembl:ENSG00000168002(gene)|ensembl:ENST00000301788(transcript)|go:"GO:0000291"(nuclear-transcribed mRNA catabolic process, exonucleolytic)|go:"GO:0000932"(P-body)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006915"(apoptotic process)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR003029(S1, RNA binding)|interpro:IPR005576(RNA polymerase Rpb7, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR036898|mint:P62487|rcsb pdb:2C35|rcsb pdb:5IYA|rcsb pdb:5IY6|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|rcsb pdb:5IY7|reactome:R-HSA-167200|reactome:R-HSA-167238|rcsb pdb:5IY8|rcsb pdb:5IY9|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-5601884|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|refseq:NP_002687.1|dip:DIP-32663N - - comment:"author score: 39" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dUgR7zxbKAcYqPKb8teHBLgUhWY9606 rogid:MtnIweuhSqLFov0c40uOiwv8Eas9606 rigid:nyMqHiCBy+SHw8GrglvfiFfj2Z4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96HR3 uniprotkb:P24863 intact:EBI-394659|uniprotkb:C6GKU9|intact:EBI-11137618|ensembl:ENSP00000297347 intact:EBI-395261|uniprotkb:Q9H543|ensembl:ENSP00000428982|uniprotkb:B4DPZ1 psi-mi:med30_human(display_long)|uniprotkb:TRAP25(gene name synonym)|uniprotkb:MED30(gene name)|psi-mi:MED30(display_short)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)|uniprotkb:TRAP/Mediator complex component TRAP25(gene name synonym)|uniprotkb:THRAP6(gene name synonym) psi-mi:ccnc_human(display_long)|uniprotkb:CCNC(gene name)|psi-mi:CCNC(display_short)|uniprotkb:SRB11 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480905|imex:IM-26985-487 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_542382.1|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|mint:Q96HR3|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001269915.1|ensembl:ENSG00000164758(gene)|ensembl:ENST00000297347(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity) ensembl:ENSG00000112237(gene)|ensembl:ENST00000520429(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR028367|interpro:IPR036915|interpro:IPR043198|mint:P24863|rcsb pdb:5XQX|rcsb pdb:5XS2|rcsb pdb:6QTG|rcsb pdb:6QTJ|rcsb pdb:6R3S|rcsb pdb:6T41|rcsb pdb:6TPA|rcsb pdb:6Y0A|reactome:R-HSA-1989781|reactome:R-HSA-2122947|reactome:R-HSA-212436|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-381340|rcsb pdb:3RGF|rcsb pdb:4CRL|rcsb pdb:4F6S|rcsb pdb:4F6U|rcsb pdb:4F6W|rcsb pdb:4F70|rcsb pdb:4F7J|rcsb pdb:4F7L|rcsb pdb:4F7N|rcsb pdb:4F7S|rcsb pdb:4G6L|rcsb pdb:5BNJ|rcsb pdb:5CEI|rcsb pdb:5FGK|rcsb pdb:5HBE|rcsb pdb:5HBH|rcsb pdb:5HBJ|rcsb pdb:5HNB|rcsb pdb:5HVY|rcsb pdb:5I5Z|rcsb pdb:5ICP|rcsb pdb:5IDN|rcsb pdb:5IDP|refseq:NP_005181.2|refseq:NP_001013417.1|dip:DIP-32920N - - comment:"author score: 43" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dUgR7zxbKAcYqPKb8teHBLgUhWY9606 rogid:Gu327q98H8ggQoYCb4UnR2Mcsyg9606 rigid:nyMqHiCBy+SHw8GrglvfiFfj2Z4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96HR3 uniprotkb:Q9BWU1 intact:EBI-394659|uniprotkb:C6GKU9|intact:EBI-11137618|ensembl:ENSP00000297347 intact:EBI-394593|uniprotkb:Q5JQZ7|uniprotkb:Q5JR00|uniprotkb:Q8TC78|uniprotkb:Q9UPX2|intact:EBI-28987871|ensembl:ENSP00000357907 psi-mi:med30_human(display_long)|uniprotkb:TRAP25(gene name synonym)|uniprotkb:MED30(gene name)|psi-mi:MED30(display_short)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)|uniprotkb:TRAP/Mediator complex component TRAP25(gene name synonym)|uniprotkb:THRAP6(gene name synonym) psi-mi:cdk19_human(display_long)|uniprotkb:CDK19(gene name)|psi-mi:CDK19(display_short)|uniprotkb:CDC2-related protein kinase 6(gene name synonym)|uniprotkb:Death-preventing kinase(gene name synonym)|uniprotkb:Cyclin-dependent kinase 11(gene name synonym)|uniprotkb:CDK11(gene name synonym)|uniprotkb:KIAA1028(gene name synonym)|uniprotkb:CDC2L6(gene name synonym)|uniprotkb:Cell division cycle 2-like protein kinase 6(gene name synonym)|uniprotkb:Cell division protein kinase 19(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480905|imex:IM-26985-487 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_542382.1|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|mint:Q96HR3|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001269915.1|ensembl:ENSG00000164758(gene)|ensembl:ENST00000297347(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_055891.1|refseq:NP_001287889.1|refseq:NP_001287892.1|refseq:NP_001287893.1|ensembl:ENSG00000155111(gene)|ensembl:ENST00000368911(transcript)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0016592"(mediator complex)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q9BWU1|reactome:R-HSA-1989781|reactome:R-HSA-381340|ensembl:ENST00000323817|ensembl:ENSP00000317665|ensembl:ENSP00000357907|dip:DIP-29013N - - comment:"author score: 51" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dUgR7zxbKAcYqPKb8teHBLgUhWY9606 rogid:80Ngzl9uqRnqMjGnO5v7j72eY7E9606 rigid:nyMqHiCBy+SHw8GrglvfiFfj2Z4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96HR3 uniprotkb:Q9UHV7 intact:EBI-394659|uniprotkb:C6GKU9|intact:EBI-11137618|ensembl:ENSP00000297347 intact:EBI-394440|uniprotkb:O60334|uniprotkb:B2RU05|ensembl:ENSP00000380888 psi-mi:med30_human(display_long)|uniprotkb:TRAP25(gene name synonym)|uniprotkb:MED30(gene name)|psi-mi:MED30(display_short)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)|uniprotkb:TRAP/Mediator complex component TRAP25(gene name synonym)|uniprotkb:THRAP6(gene name synonym) psi-mi:med13_human(display_long)|uniprotkb:TRAP240(gene name synonym)|uniprotkb:MED13(gene name)|psi-mi:MED13(display_short)|uniprotkb:ARC250(gene name synonym)|uniprotkb:KIAA0593(gene name synonym)|uniprotkb:Mediator complex subunit 13(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 240 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 1(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex component DRIP250(gene name synonym)|uniprotkb:Activator-recruited cofactor 250 kDa component(gene name synonym)|uniprotkb:THRAP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480905|imex:IM-26985-487 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_542382.1|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|mint:Q96HR3|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001269915.1|ensembl:ENSG00000164758(gene)|ensembl:ENST00000297347(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_005112.2|ensembl:ENSG00000108510(gene)|ensembl:ENST00000397786(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR009401(TRAP240)|interpro:IPR041285|mint:Q9UHV7|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31468N - - comment:"author score: 56" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dUgR7zxbKAcYqPKb8teHBLgUhWY9606 rogid:ZNWwmsetsKLA56joRzRL0UKjq9Y9606 rigid:nyMqHiCBy+SHw8GrglvfiFfj2Z4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96HR3 uniprotkb:P30876 intact:EBI-394659|uniprotkb:C6GKU9|intact:EBI-11137618|ensembl:ENSP00000297347 intact:EBI-394712|uniprotkb:Q8IZ61|uniprotkb:A8K1A8|ensembl:ENSP00000312735|ensembl:ENSP00000370625 psi-mi:med30_human(display_long)|uniprotkb:TRAP25(gene name synonym)|uniprotkb:MED30(gene name)|psi-mi:MED30(display_short)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)|uniprotkb:TRAP/Mediator complex component TRAP25(gene name synonym)|uniprotkb:THRAP6(gene name synonym) psi-mi:rpb2_human(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit B(gene name synonym)|uniprotkb:RNA polymerase II subunit B2(gene name synonym)|uniprotkb:RNA polymerase II subunit 2(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 140 kDa polypeptide(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480905|imex:IM-26985-487 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_542382.1|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|mint:Q96HR3|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001269915.1|ensembl:ENSG00000164758(gene)|ensembl:ENST00000297347(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_000929.1|refseq:NP_001290197.1|refseq:NP_001290198.1|ensembl:ENSG00000047315(gene)|ensembl:ENST00000314595(transcript)|ensembl:ENST00000381227(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|mint:P30876|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32910N - - comment:"author score: 66" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dUgR7zxbKAcYqPKb8teHBLgUhWY9606 rogid:YhEjtfLk2QnbRPefOp8ZHX0ejak9606 rigid:nyMqHiCBy+SHw8GrglvfiFfj2Z4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96HR3 uniprotkb:P24928 intact:EBI-394659|uniprotkb:C6GKU9|intact:EBI-11137618|ensembl:ENSP00000297347 intact:EBI-295301|uniprotkb:A6NN93|uniprotkb:B9EH88|uniprotkb:Q6NX41|intact:EBI-17957133|intact:EBI-14758660|intact:EBI-13324911|intact:EBI-23311874 psi-mi:med30_human(display_long)|uniprotkb:TRAP25(gene name synonym)|uniprotkb:MED30(gene name)|psi-mi:MED30(display_short)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)|uniprotkb:TRAP/Mediator complex component TRAP25(gene name synonym)|uniprotkb:THRAP6(gene name synonym) psi-mi:rpb1_human(display_long)|uniprotkb:POLR2A(gene name)|psi-mi:POLR2A(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit A(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:POLR2(gene name synonym)|uniprotkb:RNA-directed RNA polymerase II subunit RPB1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480905|imex:IM-26985-487 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_542382.1|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|mint:Q96HR3|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001269915.1|ensembl:ENSG00000164758(gene)|ensembl:ENST00000297347(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_000928.1|mint:P24928|dip:DIP-29011N|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0019900"(kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:2GHQ|rcsb pdb:2GHT|rcsb pdb:2LTO|rcsb pdb:3D9K|rcsb pdb:3D9L|rcsb pdb:3D9M|rcsb pdb:3D9N|rcsb pdb:3D9O|rcsb pdb:3D9P|rcsb pdb:4JXT|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:5M3H|rcsb pdb:5M3J|rcsb pdb:6DRD|rcsb pdb:6F5P|rcsb pdb:6G0R|rcsb pdb:6IC8|rcsb pdb:6IC9|rcsb pdb:6O9L|rcsb pdb:6Q5Y|rcsb pdb:6XKB|rcsb pdb:6XRE|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095 - - comment:"author score: 70" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dUgR7zxbKAcYqPKb8teHBLgUhWY9606 rogid:Si2fgh4AMaNtlzvSQhvsuPusX7s9606 rigid:nyMqHiCBy+SHw8GrglvfiFfj2Z4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96HR3 uniprotkb:Q71F56 intact:EBI-394659|uniprotkb:C6GKU9|intact:EBI-11137618|ensembl:ENSP00000297347 intact:EBI-394435|uniprotkb:A1L469|uniprotkb:Q68DN4|uniprotkb:Q9H8C0|uniprotkb:Q9NSY9|uniprotkb:Q9UFD8|uniprotkb:Q9UPX5|ensembl:ENSP00000281928 psi-mi:med30_human(display_long)|uniprotkb:TRAP25(gene name synonym)|uniprotkb:MED30(gene name)|psi-mi:MED30(display_short)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)|uniprotkb:TRAP/Mediator complex component TRAP25(gene name synonym)|uniprotkb:THRAP6(gene name synonym) psi-mi:md13l_human(display_long)|uniprotkb:Mediator complex subunit 13-like(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 2(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 240 kDa component-like(gene name synonym)|uniprotkb:MED13L(gene name)|psi-mi:MED13L(display_short)|uniprotkb:KIAA1025(gene name synonym)|uniprotkb:PROSIT240(gene name synonym)|uniprotkb:THRAP2(gene name synonym)|uniprotkb:TRAP240L(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480905|imex:IM-26985-487 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_542382.1|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|mint:Q96HR3|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001269915.1|ensembl:ENSG00000164758(gene)|ensembl:ENST00000297347(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_056150.1|ensembl:ENSG00000123066(gene)|ensembl:ENST00000281928(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR009401(TRAP240)|interpro:IPR021643|interpro:IPR041285|mint:Q71F56|reactome:R-HSA-1989781|reactome:R-HSA-381340 - - comment:"author score: 73" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dUgR7zxbKAcYqPKb8teHBLgUhWY9606 rogid:Zdj5dM/HEWW8zS27yaXsR+ZOxZs9606 rigid:nyMqHiCBy+SHw8GrglvfiFfj2Z4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96HR3 uniprotkb:P36954 intact:EBI-394659|uniprotkb:C6GKU9|intact:EBI-11137618|ensembl:ENSP00000297347 intact:EBI-395202|uniprotkb:Q6NW05|uniprotkb:B2R5J2|ensembl:ENSP00000221859 psi-mi:med30_human(display_long)|uniprotkb:TRAP25(gene name synonym)|uniprotkb:MED30(gene name)|psi-mi:MED30(display_short)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)|uniprotkb:TRAP/Mediator complex component TRAP25(gene name synonym)|uniprotkb:THRAP6(gene name synonym) psi-mi:rpb9_human(display_long)|uniprotkb:POLR2I(gene name)|psi-mi:POLR2I(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit I(gene name synonym)|uniprotkb:RNA polymerase II 14.5 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480905|imex:IM-26985-487 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_542382.1|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|mint:Q96HR3|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001269915.1|ensembl:ENSG00000164758(gene)|ensembl:ENST00000297347(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_006224.1|ensembl:ENSG00000105258(gene)|ensembl:ENST00000221859(transcript)|go:"GO:0001193"(maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034012|mint:P36954|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32917N - - comment:"author score: 78" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dUgR7zxbKAcYqPKb8teHBLgUhWY9606 rogid:YZUW2UDzj1RhCC46iaX1LvYayNA9606 rigid:nyMqHiCBy+SHw8GrglvfiFfj2Z4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96HR3 uniprotkb:P19387 intact:EBI-394659|uniprotkb:C6GKU9|intact:EBI-11137618|ensembl:ENSP00000297347 intact:EBI-394729|uniprotkb:O15161|ensembl:ENSP00000219252 psi-mi:med30_human(display_long)|uniprotkb:TRAP25(gene name synonym)|uniprotkb:MED30(gene name)|psi-mi:MED30(display_short)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)|uniprotkb:TRAP/Mediator complex component TRAP25(gene name synonym)|uniprotkb:THRAP6(gene name synonym) psi-mi:rpb3_human(display_long)|uniprotkb:POLR2C(gene name)|psi-mi:POLR2C(display_short)|uniprotkb:A-152E5.7(orf name)|uniprotkb:DNA-directed RNA polymerase II subunit C(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 33 kDa polypeptide(gene name synonym)|uniprotkb:RPB31(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480905|imex:IM-26985-487 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_542382.1|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|mint:Q96HR3|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001269915.1|ensembl:ENSG00000164758(gene)|ensembl:ENST00000297347(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_116558.1|ensembl:ENSG00000102978(gene)|ensembl:ENST00000219252(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001514(DNA-directed RNA polymerase, 30-40 kDa subunit, conserved site)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR036603|interpro:IPR036643|mint:P19387|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32911N - - comment:"author score: 83" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dUgR7zxbKAcYqPKb8teHBLgUhWY9606 rogid:UXFC+i+QqB2WRgL9OiYSQ66L36c9606 rigid:nyMqHiCBy+SHw8GrglvfiFfj2Z4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96HR3 uniprotkb:Q93074 intact:EBI-394659|uniprotkb:C6GKU9|intact:EBI-11137618|ensembl:ENSP00000297347 intact:EBI-394357|uniprotkb:O15410|uniprotkb:O75557|uniprotkb:Q9UHV6|uniprotkb:Q9UND7|ensembl:ENSP00000363193 psi-mi:med30_human(display_long)|uniprotkb:TRAP25(gene name synonym)|uniprotkb:MED30(gene name)|psi-mi:MED30(display_short)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)|uniprotkb:TRAP/Mediator complex component TRAP25(gene name synonym)|uniprotkb:THRAP6(gene name synonym) psi-mi:med12_human(display_long)|uniprotkb:TRAP230(gene name synonym)|uniprotkb:MED12(gene name)|psi-mi:MED12(display_short)|uniprotkb:ARC240(gene name synonym)|uniprotkb:CAGH45(gene name synonym)|uniprotkb:HOPA(gene name synonym)|uniprotkb:KIAA0192(gene name synonym)|uniprotkb:Mediator complex subunit 12(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 230 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 240 kDa component(gene name synonym)|uniprotkb:CAG repeat protein 45(gene name synonym)|uniprotkb:OPA-containing protein(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 11 protein(gene name synonym)|uniprotkb:TNRC11(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480905|imex:IM-26985-487 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_542382.1|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|mint:Q96HR3|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001269915.1|ensembl:ENSG00000164758(gene)|ensembl:ENST00000297347(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_005111.2|ensembl:ENSG00000184634(gene)|ensembl:ENST00000374080(transcript)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0090245"(axis elongation involved in somitogenesis)|go:"GO:1990403"(embryonic brain development)|interpro:IPR019035|interpro:IPR021989|interpro:IPR021990|mint:Q93074|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0014044"(Schwann cell development)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|dip:DIP-31459N - - comment:"author score: 97" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dUgR7zxbKAcYqPKb8teHBLgUhWY9606 rogid:soNqTi3/n+qnj+P4AX/cPJzTK2U9606 rigid:nyMqHiCBy+SHw8GrglvfiFfj2Z4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96HR3 uniprotkb:Q9BUE0 intact:EBI-394659|uniprotkb:C6GKU9|intact:EBI-11137618|ensembl:ENSP00000297347 intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184 psi-mi:med30_human(display_long)|uniprotkb:TRAP25(gene name synonym)|uniprotkb:MED30(gene name)|psi-mi:MED30(display_short)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)|uniprotkb:TRAP/Mediator complex component TRAP25(gene name synonym)|uniprotkb:THRAP6(gene name synonym) psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480905|imex:IM-26985-487 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_542382.1|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|mint:Q96HR3|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001269915.1|ensembl:ENSG00000164758(gene)|ensembl:ENST00000297347(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 - - comment:"author score: 106" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dUgR7zxbKAcYqPKb8teHBLgUhWY9606 rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606 rigid:nyMqHiCBy+SHw8GrglvfiFfj2Z4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96HR3 uniprotkb:O95402 intact:EBI-394659|uniprotkb:C6GKU9|intact:EBI-11137618|ensembl:ENSP00000297347 intact:EBI-394392|uniprotkb:A1A4S3|uniprotkb:Q0VGB6|intact:EBI-28974475|ensembl:ENSP00000263390 psi-mi:med30_human(display_long)|uniprotkb:TRAP25(gene name synonym)|uniprotkb:MED30(gene name)|psi-mi:MED30(display_short)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)|uniprotkb:TRAP/Mediator complex component TRAP25(gene name synonym)|uniprotkb:THRAP6(gene name synonym) psi-mi:med26_human(display_long)|uniprotkb:ARC70(gene name synonym)|uniprotkb:MED26(gene name)|psi-mi:MED26(display_short)|uniprotkb:Mediator complex subunit 26(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 7(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP70(gene name synonym)|uniprotkb:Activator-recruited cofactor 70 kDa component(gene name synonym)|uniprotkb:CRSP7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480905|imex:IM-26985-487 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_542382.1|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|mint:Q96HR3|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001269915.1|ensembl:ENSG00000164758(gene)|ensembl:ENST00000297347(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity) ensembl:ENSP00000263390|ensembl:ENST00000611692|ensembl:ENSP00000484490|refseq:NP_004822.2|ensembl:ENSG00000105085(gene)|ensembl:ENST00000263390(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR017923|interpro:IPR031416|interpro:IPR031417|interpro:IPR035441|interpro:IPR042376|mint:O95402|rcsb pdb:5ODD|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31464N - - comment:"author score: 119" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dUgR7zxbKAcYqPKb8teHBLgUhWY9606 rogid:1kRmQ+QH5uQkKVfjo2Rc2SkAyKc9606 rigid:nyMqHiCBy+SHw8GrglvfiFfj2Z4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96HR3 uniprotkb:Q15528 intact:EBI-394659|uniprotkb:C6GKU9|intact:EBI-11137618|ensembl:ENSP00000297347 intact:EBI-394687|uniprotkb:Q5T8U0|uniprotkb:O76072|uniprotkb:B3KW83|uniprotkb:B3KWX4|ensembl:ENSP00000342343|ensembl:ENSP00000482438|ensembl:ENSP00000485880|ensembl:ENSP00000487580 psi-mi:med30_human(display_long)|uniprotkb:TRAP25(gene name synonym)|uniprotkb:MED30(gene name)|psi-mi:MED30(display_short)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)|uniprotkb:TRAP/Mediator complex component TRAP25(gene name synonym)|uniprotkb:THRAP6(gene name synonym) psi-mi:med22_human(display_long)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:MED22(gene name)|psi-mi:MED22(display_short)|uniprotkb:Surfeit locus protein 5(gene name synonym)|uniprotkb:SURF5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480905|imex:IM-26985-487 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_542382.1|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|mint:Q96HR3|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001269915.1|ensembl:ENSG00000164758(gene)|ensembl:ENST00000297347(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_598395.1|refseq:NP_852468.1|ensembl:ENSG00000148297(gene)|ensembl:ENSG00000281022(gene)|ensembl:ENST00000343730(transcript)|ensembl:ENST00000610672(transcript)|ensembl:ENST00000629522(transcript)|ensembl:ENST00000631196(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR009332(Surfeit locus 5)|mint:Q15528|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 - - comment:"author score: 124" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dUgR7zxbKAcYqPKb8teHBLgUhWY9606 rogid:bAtK0Srk81ujvVt2Gj0+py7RCZY9606 rigid:nyMqHiCBy+SHw8GrglvfiFfj2Z4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96HR3 uniprotkb:Q9NWA0 intact:EBI-394659|uniprotkb:C6GKU9|intact:EBI-11137618|ensembl:ENSP00000297347 intact:EBI-394653|ensembl:ENSP00000268711 psi-mi:med30_human(display_long)|uniprotkb:TRAP25(gene name synonym)|uniprotkb:MED30(gene name)|psi-mi:MED30(display_short)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)|uniprotkb:TRAP/Mediator complex component TRAP25(gene name synonym)|uniprotkb:THRAP6(gene name synonym) psi-mi:med9_human(display_long)|uniprotkb:MED9(gene name)|psi-mi:MED9(display_short)|uniprotkb:Mediator complex subunit 9(gene name synonym)|uniprotkb:MED25(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480905|imex:IM-26985-487 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_542382.1|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|mint:Q96HR3|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001269915.1|ensembl:ENSG00000164758(gene)|ensembl:ENST00000297347(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_060489.1|ensembl:ENSG00000141026(gene)|ensembl:ENST00000268711(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR011425(RNA polymerase II transcription mediator)|interpro:IPR037212|interpro:IPR039242|mint:Q9NWA0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 - - comment:"author score: 136" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dUgR7zxbKAcYqPKb8teHBLgUhWY9606 rogid:VSYpA1Aqh2FEaZIEF/6iCIpoPEc9606 rigid:nyMqHiCBy+SHw8GrglvfiFfj2Z4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96HR3 uniprotkb:Q9Y3C7 intact:EBI-394659|uniprotkb:C6GKU9|intact:EBI-11137618|ensembl:ENSP00000297347 intact:EBI-394707|uniprotkb:B2R4L9|ensembl:ENSP00000225728 psi-mi:med30_human(display_long)|uniprotkb:TRAP25(gene name synonym)|uniprotkb:MED30(gene name)|psi-mi:MED30(display_short)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)|uniprotkb:TRAP/Mediator complex component TRAP25(gene name synonym)|uniprotkb:THRAP6(gene name synonym) psi-mi:med31_human(display_long)|uniprotkb:CGI-125(orf name)|uniprotkb:SOH1(gene name synonym)|uniprotkb:MED31(gene name)|psi-mi:MED31(display_short)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480905|imex:IM-26985-487 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_542382.1|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|mint:Q96HR3|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001269915.1|ensembl:ENSG00000164758(gene)|ensembl:ENST00000297347(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_057144.1|ensembl:ENSG00000108590(gene)|ensembl:ENST00000225728(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|mint:Q9Y3C7|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 - - comment:"author score: 137" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dUgR7zxbKAcYqPKb8teHBLgUhWY9606 rogid:QRmf6b+uoUOubBcvJbBfl9NgRTQ9606 rigid:nyMqHiCBy+SHw8GrglvfiFfj2Z4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96HR3 uniprotkb:Q15648 intact:EBI-394659|uniprotkb:C6GKU9|intact:EBI-11137618|ensembl:ENSP00000297347 intact:EBI-394459|uniprotkb:A2RRQ6|uniprotkb:O43810|uniprotkb:O75447|uniprotkb:Q6P9H7|uniprotkb:Q6PK58|uniprotkb:Q9HD39|ensembl:ENSP00000300651 psi-mi:med30_human(display_long)|uniprotkb:TRAP25(gene name synonym)|uniprotkb:MED30(gene name)|psi-mi:MED30(display_short)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)|uniprotkb:TRAP/Mediator complex component TRAP25(gene name synonym)|uniprotkb:THRAP6(gene name synonym) psi-mi:med1_human(display_long)|uniprotkb:TRIP2(gene name synonym)|uniprotkb:MED1(gene name)|psi-mi:MED1(display_short)|uniprotkb:ARC205(gene name synonym)|uniprotkb:DRIP205(gene name synonym)|uniprotkb:TRAP220(gene name synonym)|uniprotkb:Activator-recruited cofactor 205 kDa component(gene name synonym)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-binding protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 220 kDa component(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 2(gene name synonym)|uniprotkb:p53 regulatory protein RB18A(gene name synonym)|uniprotkb:Vitamin D receptor-interacting protein complex component DRIP205(gene name synonym)|uniprotkb:CRSP1(gene name synonym)|uniprotkb:CRSP200(gene name synonym)|uniprotkb:DRIP230(gene name synonym)|uniprotkb:PBP(gene name synonym)|uniprotkb:PPARBP(gene name synonym)|uniprotkb:PPARGBP(gene name synonym)|uniprotkb:RB18A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480905|imex:IM-26985-487 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_542382.1|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|mint:Q96HR3|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001269915.1|ensembl:ENSG00000164758(gene)|ensembl:ENST00000297347(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_004765.2|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR019680|mint:Q15648|rcsb pdb:1RJK|rcsb pdb:1RK3|rcsb pdb:1RKG|rcsb pdb:1RKH|rcsb pdb:2O4J|rcsb pdb:2O4R|rcsb pdb:2ZFX|rcsb pdb:3A2H|rcsb pdb:3AUN|rcsb pdb:3VJS|rcsb pdb:3VJT|rcsb pdb:3VRT|rcsb pdb:3VRU|rcsb pdb:3VRV|rcsb pdb:3VRW|rcsb pdb:3W0G|rcsb pdb:3W0H|rcsb pdb:3W0I|rcsb pdb:3W0J|rcsb pdb:3W5P|rcsb pdb:3W5Q|rcsb pdb:3W5R|rcsb pdb:3W5T|rcsb pdb:3WT5|rcsb pdb:3WT6|rcsb pdb:3WT7|rcsb pdb:3WTQ|rcsb pdb:4YNK|rcsb pdb:5AWJ|rcsb pdb:5AWK|rcsb pdb:5B41|rcsb pdb:5B5B|rcsb pdb:5GIC|rcsb pdb:5GID|rcsb pdb:5GIE|rcsb pdb:5XPM|rcsb pdb:5XPN|rcsb pdb:5XPO|rcsb pdb:5XPP|rcsb pdb:5XUQ|rcsb pdb:5XZF|rcsb pdb:5XZH|rcsb pdb:5ZWE|rcsb pdb:5ZWF|rcsb pdb:5ZWH|rcsb pdb:5ZWI|rcsb pdb:6D94|rcsb pdb:6JEZ|rcsb pdb:6K5O|rcsb pdb:6ONJ|rcsb pdb:7C7V|rcsb pdb:7C7W|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9707564|reactome:R-HSA-9707616|ensembl:ENSG00000125686(gene)|ensembl:ENST00000300651(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003406"(retinal pigment epithelium development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0050693"(LBD domain binding)|dip:DIP-24212N - - comment:"author score: 139" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dUgR7zxbKAcYqPKb8teHBLgUhWY9606 rogid:A4EIAri9zYycSlTA7s6NzbOi9n49606 rigid:nyMqHiCBy+SHw8GrglvfiFfj2Z4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96HR3 uniprotkb:Q96G25 intact:EBI-394659|uniprotkb:C6GKU9|intact:EBI-11137618|ensembl:ENSP00000297347 intact:EBI-394405|uniprotkb:A9IZ91|uniprotkb:Q96FQ4|uniprotkb:A9IZ92|uniprotkb:Q5JUY8|ensembl:ENSP00000361535 psi-mi:med30_human(display_long)|uniprotkb:TRAP25(gene name synonym)|uniprotkb:MED30(gene name)|psi-mi:MED30(display_short)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)|uniprotkb:TRAP/Mediator complex component TRAP25(gene name synonym)|uniprotkb:THRAP6(gene name synonym) psi-mi:med8_human(display_long)|uniprotkb:MED8(gene name)|psi-mi:MED8(display_short)|uniprotkb:Mediator complex subunit 8(gene name synonym)|uniprotkb:Activator-recruited cofactor 32 kDa component(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480905|imex:IM-26985-487 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_542382.1|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|mint:Q96HR3|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001269915.1|ensembl:ENSG00000164758(gene)|ensembl:ENST00000297347(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_443109.2|refseq:NP_963836.2|refseq:NP_001001653.1|ensembl:ENSG00000159479(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|mint:Q96G25|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENST00000372457(transcript) - - comment:"author score: 146" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dUgR7zxbKAcYqPKb8teHBLgUhWY9606 rogid:e/ye7rfa2E1XOPb5vVhI9Nvqmxw9606 rigid:nyMqHiCBy+SHw8GrglvfiFfj2Z4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96HR3 uniprotkb:O60244 intact:EBI-394659|uniprotkb:C6GKU9|intact:EBI-11137618|ensembl:ENSP00000297347 intact:EBI-394489|uniprotkb:Q4KMR7|uniprotkb:Q9UNB3|ensembl:ENSP00000323720 psi-mi:med30_human(display_long)|uniprotkb:TRAP25(gene name synonym)|uniprotkb:MED30(gene name)|psi-mi:MED30(display_short)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)|uniprotkb:TRAP/Mediator complex component TRAP25(gene name synonym)|uniprotkb:THRAP6(gene name synonym) psi-mi:med14_human(display_long)|uniprotkb:TRAP170(gene name synonym)|uniprotkb:MED14(gene name)|psi-mi:MED14(display_short)|uniprotkb:ARC150(gene name synonym)|uniprotkb:DRIP150(gene name synonym)|uniprotkb:EXLM1(gene name synonym)|uniprotkb:RGR1(gene name synonym)|uniprotkb:Mediator complex subunit 14(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 2(gene name synonym)|uniprotkb:RGR1 homolog(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP150(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 150 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 170 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 150 kDa component(gene name synonym)|uniprotkb:CRSP2(gene name synonym)|uniprotkb:CXorf4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480905|imex:IM-26985-487 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_542382.1|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|mint:Q96HR3|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001269915.1|ensembl:ENSG00000164758(gene)|ensembl:ENST00000297347(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_004220.2|ensembl:ENSG00000180182(gene)|ensembl:ENST00000324817(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR013947(Mediator complex, subunit MED14)|mint:O60244|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31460N - - comment:"author score: 153" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dUgR7zxbKAcYqPKb8teHBLgUhWY9606 rogid:73RBAnwmB4Lyl/kcsg7NKSUmA4c9606 rigid:nyMqHiCBy+SHw8GrglvfiFfj2Z4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96HR3 uniprotkb:O75586 intact:EBI-394659|uniprotkb:C6GKU9|intact:EBI-11137618|ensembl:ENSP00000297347 intact:EBI-394624|uniprotkb:Q6FHQ4|uniprotkb:Q9BTH1|uniprotkb:Q9UHL1|uniprotkb:O15401|uniprotkb:Q53FE3|uniprotkb:Q53HJ3|uniprotkb:B4DU17|uniprotkb:B4E2P0|ensembl:ENSP00000256379 psi-mi:med30_human(display_long)|uniprotkb:TRAP25(gene name synonym)|uniprotkb:MED30(gene name)|psi-mi:MED30(display_short)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)|uniprotkb:TRAP/Mediator complex component TRAP25(gene name synonym)|uniprotkb:THRAP6(gene name synonym) psi-mi:med6_human(display_long)|uniprotkb:ARC33(gene name synonym)|uniprotkb:MED6(gene name)|psi-mi:MED6(display_short)|uniprotkb:Mediator complex subunit 6(gene name synonym)|uniprotkb:Activator-recruited cofactor 33 kDa component(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-28(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480905|imex:IM-26985-487 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_542382.1|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|mint:Q96HR3|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001269915.1|ensembl:ENSG00000164758(gene)|ensembl:ENST00000297347(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_005457.2|refseq:NP_001271138.1|refseq:NP_001271139.1|refseq:NP_001271140.1|ensembl:ENSG00000133997(gene)|ensembl:ENST00000256379(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR007018(MED6 mediator)|interpro:IPR016820(Mediator complex, subunit 6, metazoa/plant)|interpro:IPR038566|mint:O75586|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31456N - - comment:"author score: 153" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dUgR7zxbKAcYqPKb8teHBLgUhWY9606 rogid:QYK+2tX/HC1OGGPu3b3S1v/ODR89606 rigid:nyMqHiCBy+SHw8GrglvfiFfj2Z4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96HR3 uniprotkb:Q9P086 intact:EBI-394659|uniprotkb:C6GKU9|intact:EBI-11137618|ensembl:ENSP00000297347 intact:EBI-394704|uniprotkb:Q6NS89|ensembl:ENSP00000293777 psi-mi:med30_human(display_long)|uniprotkb:TRAP25(gene name synonym)|uniprotkb:MED30(gene name)|psi-mi:MED30(display_short)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)|uniprotkb:TRAP/Mediator complex component TRAP25(gene name synonym)|uniprotkb:THRAP6(gene name synonym) psi-mi:med11_human(display_long)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:MED11(gene name)|psi-mi:MED11(display_short)|uniprotkb:HSPC296(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480905|imex:IM-26985-487 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_542382.1|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|mint:Q96HR3|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001269915.1|ensembl:ENSG00000164758(gene)|ensembl:ENST00000297347(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_001291929.1|refseq:NP_001001683.1|ensembl:ENSG00000161920(gene)|ensembl:ENST00000293777(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019404|mint:Q9P086|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|go:"GO:0003712"(transcription coregulator activity) - - comment:"author score: 155" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dUgR7zxbKAcYqPKb8teHBLgUhWY9606 rogid:y7SZi5hIo5aOatJSZi98Hqt082A9606 rigid:nyMqHiCBy+SHw8GrglvfiFfj2Z4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96HR3 uniprotkb:A0JLT2 intact:EBI-394659|uniprotkb:C6GKU9|intact:EBI-11137618|ensembl:ENSP00000297347 intact:EBI-394430|uniprotkb:Q8IV02|intact:EBI-394763|uniprotkb:Q8IZD1 psi-mi:med30_human(display_long)|uniprotkb:TRAP25(gene name synonym)|uniprotkb:MED30(gene name)|psi-mi:MED30(display_short)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)|uniprotkb:TRAP/Mediator complex component TRAP25(gene name synonym)|uniprotkb:THRAP6(gene name synonym) psi-mi:med19_human(display_long)|uniprotkb:MED19(gene name)|psi-mi:MED19(display_short)|uniprotkb:LCMR1(gene name synonym)|uniprotkb:Lung cancer metastasis-related protein 1(gene name synonym)|uniprotkb:Mediator complex subunit 19(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480905|imex:IM-26985-487 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_542382.1|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|mint:Q96HR3|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001269915.1|ensembl:ENSG00000164758(gene)|ensembl:ENST00000297347(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_001304007.1|refseq:NP_703151.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR019403|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|mint:A0JLT2|dip:DIP-31467N - - comment:"author score: 157" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dUgR7zxbKAcYqPKb8teHBLgUhWY9606 rogid:zcHhU2hQvuTpkFZz/xEKYmjrwOA9606 rigid:nyMqHiCBy+SHw8GrglvfiFfj2Z4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96HR3 uniprotkb:Q9H204 intact:EBI-394659|uniprotkb:C6GKU9|intact:EBI-11137618|ensembl:ENSP00000297347 intact:EBI-514199|uniprotkb:Q9BZJ5|ensembl:ENSP00000237380 psi-mi:med30_human(display_long)|uniprotkb:TRAP25(gene name synonym)|uniprotkb:MED30(gene name)|psi-mi:MED30(display_short)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)|uniprotkb:TRAP/Mediator complex component TRAP25(gene name synonym)|uniprotkb:THRAP6(gene name synonym) psi-mi:med28_human(display_long)|uniprotkb:Mediator complex subunit 28(gene name synonym)|uniprotkb:Tumor angiogenesis marker EG-1(gene name synonym)|uniprotkb:Endothelial-derived protein 1(gene name synonym)|uniprotkb:Merlin and Grb2-interacting cytoskeletal protein(gene name synonym)|uniprotkb:MED28(gene name)|psi-mi:MED28(display_short)|uniprotkb:EG1(gene name synonym)|uniprotkb:FKSG20(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480905|imex:IM-26985-487 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_542382.1|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|mint:Q96HR3|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001269915.1|ensembl:ENSG00000164758(gene)|ensembl:ENST00000297347(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_079481.2|ensembl:ENSG00000118579(gene)|ensembl:ENST00000237380(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0051151"(negative regulation of smooth muscle cell differentiation)|interpro:IPR021640|mint:Q9H204|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 - - comment:"author score: 158" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dUgR7zxbKAcYqPKb8teHBLgUhWY9606 rogid:1gt/0vP7vWJ+M1fU+qZPcWGj34U9606 rigid:nyMqHiCBy+SHw8GrglvfiFfj2Z4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96HR3 uniprotkb:Q9BTT4 intact:EBI-394659|uniprotkb:C6GKU9|intact:EBI-11137618|ensembl:ENSP00000297347 intact:EBI-394354|uniprotkb:C6G491|ensembl:ENSP00000255764 psi-mi:med30_human(display_long)|uniprotkb:TRAP25(gene name synonym)|uniprotkb:MED30(gene name)|psi-mi:MED30(display_short)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)|uniprotkb:TRAP/Mediator complex component TRAP25(gene name synonym)|uniprotkb:THRAP6(gene name synonym) psi-mi:med10_human(display_long)|uniprotkb:MED10(gene name)|psi-mi:MED10(display_short)|uniprotkb:L6(orf name)|uniprotkb:TRG17(orf name)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Transformation-related gene 17 protein(gene name synonym)|uniprotkb:Transformation-related gene 20 protein(gene name synonym)|uniprotkb:TRG20(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480905|imex:IM-26985-487 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_542382.1|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|mint:Q96HR3|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001269915.1|ensembl:ENSG00000164758(gene)|ensembl:ENST00000297347(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity) ensembl:ENSG00000133398(gene)|ensembl:ENST00000255764(transcript)|refseq:NP_115662.2|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019145|mint:Q9BTT4|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|go:"GO:0000151"(ubiquitin ligase complex)|dip:DIP-31457N - - comment:"author score: 164" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dUgR7zxbKAcYqPKb8teHBLgUhWY9606 rogid:LzJW7C8kl2pWmffOjo8S/FNSS9I9606 rigid:nyMqHiCBy+SHw8GrglvfiFfj2Z4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96HR3 uniprotkb:Q6P2C8 intact:EBI-394659|uniprotkb:C6GKU9|intact:EBI-11137618|ensembl:ENSP00000297347 intact:EBI-394603|uniprotkb:Q4F964|uniprotkb:O95401|uniprotkb:Q5VTA4|uniprotkb:Q5VTA5|uniprotkb:Q9BU57|uniprotkb:Q9NYR4|uniprotkb:V9GYV9|ensembl:ENSP00000292035 psi-mi:med30_human(display_long)|uniprotkb:TRAP25(gene name synonym)|uniprotkb:MED30(gene name)|psi-mi:MED30(display_short)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)|uniprotkb:TRAP/Mediator complex component TRAP25(gene name synonym)|uniprotkb:THRAP6(gene name synonym) psi-mi:med27_human(display_long)|uniprotkb:MED27(gene name)|psi-mi:MED27(display_short)|uniprotkb:Mediator complex subunit 27(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 8(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP34(gene name synonym)|uniprotkb:P37 TRAP/SMCC/PC2 subunit(gene name synonym)|uniprotkb:CRSP34(gene name synonym)|uniprotkb:CRSP8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480905|imex:IM-26985-487 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_542382.1|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|mint:Q96HR3|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001269915.1|ensembl:ENSG00000164758(gene)|ensembl:ENST00000297347(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_001240811.1|refseq:NP_004260.2|refseq:NP_001240810.1|dip:DIP-31465N|ensembl:ENSG00000160563(gene)|ensembl:ENST00000292035(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021627|mint:Q6P2C8|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 - - comment:"author score: 168" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dUgR7zxbKAcYqPKb8teHBLgUhWY9606 rogid:V1clNhbtflCzCkC7OnaHGYrmQp89606 rigid:nyMqHiCBy+SHw8GrglvfiFfj2Z4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96HR3 uniprotkb:Q9H944 intact:EBI-394659|uniprotkb:C6GKU9|intact:EBI-11137618|ensembl:ENSP00000297347 intact:EBI-394644|uniprotkb:Q9Y429|uniprotkb:O95821|uniprotkb:Q5T8J4|uniprotkb:B4DE08|ensembl:ENSP00000265350 psi-mi:med30_human(display_long)|uniprotkb:TRAP25(gene name synonym)|uniprotkb:MED30(gene name)|psi-mi:MED30(display_short)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)|uniprotkb:TRAP/Mediator complex component TRAP25(gene name synonym)|uniprotkb:THRAP6(gene name synonym) psi-mi:med20_human(display_long)|uniprotkb:TRFP(gene name synonym)|uniprotkb:MED20(gene name)|psi-mi:MED20(display_short)|uniprotkb:Mediator complex subunit 20(gene name synonym)|uniprotkb:TRF-proximal protein homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480905|imex:IM-26985-487 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_542382.1|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|mint:Q96HR3|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001269915.1|ensembl:ENSG00000164758(gene)|ensembl:ENST00000297347(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_004266.2|refseq:NP_001292384.1|refseq:NP_001292385.1|refseq:NP_001292386.1|go:"GO:0016592"(mediator complex)|interpro:IPR013921(TATA-binding related factor)|mint:Q9H944|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000124641(gene)|ensembl:ENST00000265350(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|dip:DIP-31449N - - comment:"author score: 175" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dUgR7zxbKAcYqPKb8teHBLgUhWY9606 rogid:MpYOrONH6+0lKIlO6J+Szjzkw2A9606 rigid:nyMqHiCBy+SHw8GrglvfiFfj2Z4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96HR3 uniprotkb:Q9NPJ6 intact:EBI-394659|uniprotkb:C6GKU9|intact:EBI-11137618|ensembl:ENSP00000297347 intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648 psi-mi:med30_human(display_long)|uniprotkb:TRAP25(gene name synonym)|uniprotkb:MED30(gene name)|psi-mi:MED30(display_short)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)|uniprotkb:TRAP/Mediator complex component TRAP25(gene name synonym)|uniprotkb:THRAP6(gene name synonym) psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25480905|imex:IM-26985-487 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_542382.1|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|mint:Q96HR3|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001269915.1|ensembl:ENSG00000164758(gene)|ensembl:ENST00000297347(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 - - comment:"author score: 178" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dUgR7zxbKAcYqPKb8teHBLgUhWY9606 rogid:Bept2Oec50gruA9e4pf+eEUiANM9606 rigid:nyMqHiCBy+SHw8GrglvfiFfj2Z4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3C7 uniprotkb:Q16637 intact:EBI-394707|uniprotkb:B2R4L9|ensembl:ENSP00000225728 intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421 psi-mi:med31_human(display_long)|uniprotkb:CGI-125(orf name)|uniprotkb:SOH1(gene name synonym)|uniprotkb:MED31(gene name)|psi-mi:MED31(display_short)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481001|imex:IM-26985-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057144.1|ensembl:ENSG00000108590(gene)|ensembl:ENST00000225728(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|mint:Q9Y3C7|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRmf6b+uoUOubBcvJbBfl9NgRTQ9606 rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606 rigid:jH9tNTkkkEB09CZepHtY/Gt+msA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3C7 uniprotkb:Q9ULK4 intact:EBI-394707|uniprotkb:B2R4L9|ensembl:ENSP00000225728 intact:EBI-311161|uniprotkb:Q5JWT3|uniprotkb:Q5JWT4|uniprotkb:Q6P9H6|uniprotkb:O95403|uniprotkb:Q9H0J2|uniprotkb:Q9NTT9|uniprotkb:Q9NTU0|uniprotkb:Q9Y5P7|uniprotkb:Q9Y667|ensembl:ENSP00000357047|uniprotkb:B9TX55 psi-mi:med31_human(display_long)|uniprotkb:CGI-125(orf name)|uniprotkb:SOH1(gene name synonym)|uniprotkb:MED31(gene name)|psi-mi:MED31(display_short)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:med23_human(display_long)|uniprotkb:MED23(gene name)|psi-mi:MED23(display_short)|uniprotkb:ARC130(gene name synonym)|uniprotkb:DRIP130(gene name synonym)|uniprotkb:KIAA1216(gene name synonym)|uniprotkb:SUR2(gene name synonym)|uniprotkb:CRSP3(gene name synonym)|uniprotkb:Mediator complex subunit 23(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 3(gene name synonym)|uniprotkb:Protein sur-2 homolog(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP130(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 130 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 130 kDa component(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481001|imex:IM-26985-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057144.1|ensembl:ENSG00000108590(gene)|ensembl:ENST00000225728(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|mint:Q9Y3C7|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 refseq:NP_057063.2|refseq:NP_004821.2|ensembl:ENSG00000112282(gene)|ensembl:ENST00000368068(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016592"(mediator complex)|interpro:IPR021629|mint:Q9ULK4|rcsb pdb:6H02|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001257450.1|refseq:NP_001257451.1|dip:DIP-31461N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRmf6b+uoUOubBcvJbBfl9NgRTQ9606 rogid:gO5TvUnko3zY/83OHbeVmh7b+f89606 rigid:jH9tNTkkkEB09CZepHtY/Gt+msA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3C7 uniprotkb:Q8IXW5 intact:EBI-394707|uniprotkb:B2R4L9|ensembl:ENSP00000225728 intact:EBI-395878|uniprotkb:Q49AS7|uniprotkb:Q9H8Y2|ensembl:ENSP00000476948|uniprotkb:C9JKB5 psi-mi:med31_human(display_long)|uniprotkb:CGI-125(orf name)|uniprotkb:SOH1(gene name synonym)|uniprotkb:MED31(gene name)|psi-mi:MED31(display_short)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:rpap2_human(display_long)|uniprotkb:RPAP2(gene name)|psi-mi:RPAP2(display_short)|uniprotkb:C1orf82(gene name synonym)|uniprotkb:RNA polymerase II-associated protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481001|imex:IM-26985-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057144.1|ensembl:ENSG00000108590(gene)|ensembl:ENST00000225728(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|mint:Q9Y3C7|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 refseq:NP_079089.2|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008420"(RNA polymerase II CTD heptapeptide repeat phosphatase activity)|go:"GO:0009301"(snRNA transcription)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0043175"(RNA polymerase core enzyme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR007308(Protein of unknown function DUF408)|interpro:IPR038534|interpro:IPR039693|mint:Q8IXW5|rcsb pdb:7B7U|reactome:R-HSA-6807505|ensembl:ENSG00000122484(gene)|ensembl:ENST00000610020(transcript)|go:"GO:0005634"(nucleus)|dip:DIP-32939N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRmf6b+uoUOubBcvJbBfl9NgRTQ9606 rogid:niEFEvqkASycxkzfe9TYJuerUuY9606 rigid:jH9tNTkkkEB09CZepHtY/Gt+msA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3C7 uniprotkb:Q9Y2X0 intact:EBI-394707|uniprotkb:B2R4L9|ensembl:ENSP00000225728 intact:EBI-394541|uniprotkb:Q6PJT2|uniprotkb:Q96AD4|uniprotkb:Q96I35|uniprotkb:Q9Y652|ensembl:ENSP00000325612 psi-mi:med31_human(display_long)|uniprotkb:CGI-125(orf name)|uniprotkb:SOH1(gene name synonym)|uniprotkb:MED31(gene name)|psi-mi:MED31(display_short)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:med16_human(display_long)|uniprotkb:MED16(gene name)|psi-mi:MED16(display_short)|uniprotkb:Mediator complex subunit 16(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 95 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 5(gene name synonym)|uniprotkb:DRIP92(gene name synonym)|uniprotkb:THRAP5(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 92 kDa component(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481001|imex:IM-26985-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057144.1|ensembl:ENSG00000108590(gene)|ensembl:ENST00000225728(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|mint:Q9Y3C7|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 refseq:NP_005472.2|ensembl:ENSG00000175221(gene)|ensembl:ENST00000325464(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR001680(WD40 repeat)|interpro:IPR011041(Soluble quinoprotein glucose dehydrogenase)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR021665|interpro:IPR036322|mint:Q9Y2X0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31463N - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRmf6b+uoUOubBcvJbBfl9NgRTQ9606 rogid:nMHDmIPhzAalahGVVsO++rpQE/U9606 rigid:jH9tNTkkkEB09CZepHtY/Gt+msA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3C7 uniprotkb:Q86YW9 intact:EBI-394707|uniprotkb:B2R4L9|ensembl:ENSP00000225728 intact:EBI-3957138|uniprotkb:Q96PC7|uniprotkb:Q96PC8|uniprotkb:Q9H9M5|uniprotkb:Q9HCD7|uniprotkb:Q9UI69|ensembl:ENSP00000417235 psi-mi:med31_human(display_long)|uniprotkb:CGI-125(orf name)|uniprotkb:SOH1(gene name synonym)|uniprotkb:MED31(gene name)|psi-mi:MED31(display_short)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:md12l_human(display_long)|uniprotkb:MED12L(gene name)|psi-mi:MED12L(display_short)|uniprotkb:KIAA1635(gene name synonym)|uniprotkb:TNRC11L(gene name synonym)|uniprotkb:TRALP(gene name synonym)|uniprotkb:TRALPUSH(gene name synonym)|uniprotkb:Mediator complex subunit 12-like protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated-like protein(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 11 protein-like(gene name synonym)|uniprotkb:PRO0314(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481001|imex:IM-26985-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057144.1|ensembl:ENSG00000108590(gene)|ensembl:ENST00000225728(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|mint:Q9Y3C7|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 refseq:XP_011510692.1|refseq:NP_443728.3|ensembl:ENST00000309237|ensembl:ENSP00000310760|ensembl:ENST00000422248|ensembl:ENSP00000403308|ensembl:ENSP00000417235|ensembl:ENSG00000144893(gene)|ensembl:ENST00000474524(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016592"(mediator complex)|interpro:IPR019035|interpro:IPR021989|interpro:IPR021990|mint:Q86YW9 - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRmf6b+uoUOubBcvJbBfl9NgRTQ9606 rogid:85LCBTAduFNnKfHO0S10ocwWXyE9606 rigid:jH9tNTkkkEB09CZepHtY/Gt+msA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3C7 uniprotkb:P62487 intact:EBI-394707|uniprotkb:B2R4L9|ensembl:ENSP00000225728 intact:EBI-347928|ensembl:ENSP00000301788|uniprotkb:P52433|uniprotkb:Q2M1Z4|uniprotkb:B2R5C0 psi-mi:med31_human(display_long)|uniprotkb:CGI-125(orf name)|uniprotkb:SOH1(gene name synonym)|uniprotkb:MED31(gene name)|psi-mi:MED31(display_short)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:rpb7_human(display_long)|uniprotkb:POLR2G(gene name)|psi-mi:POLR2G(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit G(gene name synonym)|uniprotkb:RPB7(gene name synonym)|uniprotkb:RNA polymerase II 19 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481001|imex:IM-26985-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057144.1|ensembl:ENSG00000108590(gene)|ensembl:ENST00000225728(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|mint:Q9Y3C7|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 ensembl:ENSG00000168002(gene)|ensembl:ENST00000301788(transcript)|go:"GO:0000291"(nuclear-transcribed mRNA catabolic process, exonucleolytic)|go:"GO:0000932"(P-body)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006915"(apoptotic process)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR003029(S1, RNA binding)|interpro:IPR005576(RNA polymerase Rpb7, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR036898|mint:P62487|rcsb pdb:2C35|rcsb pdb:5IYA|rcsb pdb:5IY6|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|rcsb pdb:5IY7|reactome:R-HSA-167200|reactome:R-HSA-167238|rcsb pdb:5IY8|rcsb pdb:5IY9|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-5601884|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|refseq:NP_002687.1|dip:DIP-32663N - - comment:"author score: 29" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRmf6b+uoUOubBcvJbBfl9NgRTQ9606 rogid:MtnIweuhSqLFov0c40uOiwv8Eas9606 rigid:jH9tNTkkkEB09CZepHtY/Gt+msA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3C7 uniprotkb:Q96RN5 intact:EBI-394707|uniprotkb:B2R4L9|ensembl:ENSP00000225728 intact:EBI-394506|uniprotkb:O15413|uniprotkb:Q6IC31|uniprotkb:Q8NF16|uniprotkb:Q96CT0|uniprotkb:Q96IH7|uniprotkb:Q9P1T3|uniprotkb:D3DX31|uniprotkb:D3DX32|ensembl:ENSP00000263205 psi-mi:med31_human(display_long)|uniprotkb:CGI-125(orf name)|uniprotkb:SOH1(gene name synonym)|uniprotkb:MED31(gene name)|psi-mi:MED31(display_short)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:med15_human(display_long)|uniprotkb:MED15(gene name)|psi-mi:MED15(display_short)|uniprotkb:ARC105(gene name synonym)|uniprotkb:CTG7A(gene name synonym)|uniprotkb:Mediator complex subunit 15(gene name synonym)|uniprotkb:Positive cofactor 2 glutamine/Q-rich-associated protein(gene name synonym)|uniprotkb:TPA-inducible gene 1 protein(gene name synonym)|uniprotkb:Activator-recruited cofactor 105 kDa component(gene name synonym)|uniprotkb:CTG repeat protein 7a(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 7 protein(gene name synonym)|uniprotkb:TIG1(gene name synonym)|uniprotkb:PCQAP(gene name synonym)|uniprotkb:TNRC7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481001|imex:IM-26985-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057144.1|ensembl:ENSG00000108590(gene)|ensembl:ENST00000225728(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|mint:Q9Y3C7|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 refseq:NP_001280164.1|refseq:NP_001280165.1|refseq:NP_001003891.1|refseq:NP_056973.2|ensembl:ENSG00000099917(gene)|ensembl:ENST00000263205(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|interpro:IPR019087|interpro:IPR036529|mint:Q96RN5|rcsb pdb:2GUT|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-32908N - - comment:"author score: 29" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRmf6b+uoUOubBcvJbBfl9NgRTQ9606 rogid:8dqqSCXYc7Bp56sjogz0jpbTQLI9606 rigid:jH9tNTkkkEB09CZepHtY/Gt+msA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3C7 uniprotkb:P19388 intact:EBI-394707|uniprotkb:B2R4L9|ensembl:ENSP00000225728 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 psi-mi:med31_human(display_long)|uniprotkb:CGI-125(orf name)|uniprotkb:SOH1(gene name synonym)|uniprotkb:MED31(gene name)|psi-mi:MED31(display_short)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481001|imex:IM-26985-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057144.1|ensembl:ENSG00000108590(gene)|ensembl:ENST00000225728(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|mint:Q9Y3C7|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N - - comment:"author score: 41" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRmf6b+uoUOubBcvJbBfl9NgRTQ9606 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rigid:jH9tNTkkkEB09CZepHtY/Gt+msA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3C7 uniprotkb:P49336 intact:EBI-394707|uniprotkb:B2R4L9|ensembl:ENSP00000225728 intact:EBI-394377|uniprotkb:Q5VUF3|uniprotkb:Q6ISB5|ensembl:ENSP00000370938 psi-mi:med31_human(display_long)|uniprotkb:CGI-125(orf name)|uniprotkb:SOH1(gene name synonym)|uniprotkb:MED31(gene name)|psi-mi:MED31(display_short)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:cdk8_human(display_long)|uniprotkb:CDK8(gene name)|psi-mi:CDK8(display_short)|uniprotkb:Cell division protein kinase 8(gene name synonym)|uniprotkb:Mediator of RNA polymerase II transcription subunit CDK8(gene name synonym)|uniprotkb:Mediator complex subunit CDK8(gene name synonym)|uniprotkb:Protein kinase K35(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481001|imex:IM-26985-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057144.1|ensembl:ENSG00000108590(gene)|ensembl:ENST00000225728(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|mint:Q9Y3C7|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 refseq:NP_001305297.1|refseq:NP_001251.1|ensembl:ENSG00000132964(gene)|ensembl:ENST00000381527(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006468"(protein phosphorylation)|rcsb pdb:5FGK|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0016592"(mediator complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P49336|rcsb pdb:3RGF|rcsb pdb:4CRL|rcsb pdb:4F6S|rcsb pdb:4F6U|rcsb pdb:4F6W|rcsb pdb:4F70|rcsb pdb:4F7J|rcsb pdb:4F7L|rcsb pdb:4F7N|rcsb pdb:4F7S|rcsb pdb:4G6L|rcsb pdb:5BNJ|rcsb pdb:5CEI|rcsb pdb:5HBE|rcsb pdb:5HBH|rcsb pdb:5HBJ|rcsb pdb:5HNB|rcsb pdb:5HVY|rcsb pdb:5I5Z|rcsb pdb:5ICP|rcsb pdb:5IDN|rcsb pdb:5IDP|rcsb pdb:5XQX|rcsb pdb:5XS2|rcsb pdb:6QTG|rcsb pdb:6QTJ|rcsb pdb:6R3S|rcsb pdb:6T41|rcsb pdb:6TPA|rcsb pdb:6Y0A|reactome:R-HSA-1989781|reactome:R-HSA-2122947|reactome:R-HSA-212436|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-381340|dip:DIP-32595N - - comment:"author score: 42" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRmf6b+uoUOubBcvJbBfl9NgRTQ9606 rogid:f+78iyCfA9osCQ82uY6reu3JKzo9606 rigid:jH9tNTkkkEB09CZepHtY/Gt+msA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3C7 uniprotkb:P36954 intact:EBI-394707|uniprotkb:B2R4L9|ensembl:ENSP00000225728 intact:EBI-395202|uniprotkb:Q6NW05|uniprotkb:B2R5J2|ensembl:ENSP00000221859 psi-mi:med31_human(display_long)|uniprotkb:CGI-125(orf name)|uniprotkb:SOH1(gene name synonym)|uniprotkb:MED31(gene name)|psi-mi:MED31(display_short)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:rpb9_human(display_long)|uniprotkb:POLR2I(gene name)|psi-mi:POLR2I(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit I(gene name synonym)|uniprotkb:RNA polymerase II 14.5 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481001|imex:IM-26985-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057144.1|ensembl:ENSG00000108590(gene)|ensembl:ENST00000225728(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|mint:Q9Y3C7|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 refseq:NP_006224.1|ensembl:ENSG00000105258(gene)|ensembl:ENST00000221859(transcript)|go:"GO:0001193"(maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034012|mint:P36954|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32917N - - comment:"author score: 45" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRmf6b+uoUOubBcvJbBfl9NgRTQ9606 rogid:YZUW2UDzj1RhCC46iaX1LvYayNA9606 rigid:jH9tNTkkkEB09CZepHtY/Gt+msA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3C7 uniprotkb:P52434 intact:EBI-394707|uniprotkb:B2R4L9|ensembl:ENSP00000225728 intact:EBI-359505|uniprotkb:P53802|uniprotkb:Q969R0|ensembl:ENSP00000392913|uniprotkb:C9J413|uniprotkb:C9JBJ6|uniprotkb:C9JCU7|uniprotkb:C9JUA8 psi-mi:med31_human(display_long)|uniprotkb:CGI-125(orf name)|uniprotkb:SOH1(gene name synonym)|uniprotkb:MED31(gene name)|psi-mi:MED31(display_short)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:rpab3_human(display_long)|uniprotkb:POLR2H(gene name)|psi-mi:POLR2H(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit H(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I, II, and III 17.1 kDa polypeptide(gene name synonym)|uniprotkb:RPB17(gene name synonym)|uniprotkb:RPB8 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481001|imex:IM-26985-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057144.1|ensembl:ENSG00000108590(gene)|ensembl:ENST00000225728(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|mint:Q9Y3C7|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 ensembl:ENSG00000163882(gene)|ensembl:ENST00000456318(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032993"(protein-DNA complex)|interpro:IPR005570(RNA polymerase, Rpb8)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:P52434|rcsb pdb:2F3I|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|refseq:NP_006223.2|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|rcsb pdb:7AE3|reactome:R-HSA-1834949|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-427413|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-203927|refseq:NP_001265627.1|refseq:NP_001265628.1|refseq:NP_001265629.1|refseq:NP_001265644.1|refseq:NP_001265643.1|refseq:XP_006713729.1|refseq:XP_006713730.1|refseq:XP_016862125.1|refseq:XP_016862126.1|dip:DIP-27556N - - comment:"author score: 47" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRmf6b+uoUOubBcvJbBfl9NgRTQ9606 rogid:h7BRWDi8wRbnw/FcFo25bnlVNkE9606 rigid:jH9tNTkkkEB09CZepHtY/Gt+msA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3C7 uniprotkb:P24863 intact:EBI-394707|uniprotkb:B2R4L9|ensembl:ENSP00000225728 intact:EBI-395261|uniprotkb:Q9H543|ensembl:ENSP00000428982|uniprotkb:B4DPZ1 psi-mi:med31_human(display_long)|uniprotkb:CGI-125(orf name)|uniprotkb:SOH1(gene name synonym)|uniprotkb:MED31(gene name)|psi-mi:MED31(display_short)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:ccnc_human(display_long)|uniprotkb:CCNC(gene name)|psi-mi:CCNC(display_short)|uniprotkb:SRB11 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481001|imex:IM-26985-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057144.1|ensembl:ENSG00000108590(gene)|ensembl:ENST00000225728(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|mint:Q9Y3C7|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 ensembl:ENSG00000112237(gene)|ensembl:ENST00000520429(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR028367|interpro:IPR036915|interpro:IPR043198|mint:P24863|rcsb pdb:5XQX|rcsb pdb:5XS2|rcsb pdb:6QTG|rcsb pdb:6QTJ|rcsb pdb:6R3S|rcsb pdb:6T41|rcsb pdb:6TPA|rcsb pdb:6Y0A|reactome:R-HSA-1989781|reactome:R-HSA-2122947|reactome:R-HSA-212436|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-381340|rcsb pdb:3RGF|rcsb pdb:4CRL|rcsb pdb:4F6S|rcsb pdb:4F6U|rcsb pdb:4F6W|rcsb pdb:4F70|rcsb pdb:4F7J|rcsb pdb:4F7L|rcsb pdb:4F7N|rcsb pdb:4F7S|rcsb pdb:4G6L|rcsb pdb:5BNJ|rcsb pdb:5CEI|rcsb pdb:5FGK|rcsb pdb:5HBE|rcsb pdb:5HBH|rcsb pdb:5HBJ|rcsb pdb:5HNB|rcsb pdb:5HVY|rcsb pdb:5I5Z|rcsb pdb:5ICP|rcsb pdb:5IDN|rcsb pdb:5IDP|refseq:NP_005181.2|refseq:NP_001013417.1|dip:DIP-32920N - - comment:"author score: 52" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRmf6b+uoUOubBcvJbBfl9NgRTQ9606 rogid:Gu327q98H8ggQoYCb4UnR2Mcsyg9606 rigid:jH9tNTkkkEB09CZepHtY/Gt+msA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3C7 uniprotkb:P30876 intact:EBI-394707|uniprotkb:B2R4L9|ensembl:ENSP00000225728 intact:EBI-394712|uniprotkb:Q8IZ61|uniprotkb:A8K1A8|ensembl:ENSP00000312735|ensembl:ENSP00000370625 psi-mi:med31_human(display_long)|uniprotkb:CGI-125(orf name)|uniprotkb:SOH1(gene name synonym)|uniprotkb:MED31(gene name)|psi-mi:MED31(display_short)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:rpb2_human(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit B(gene name synonym)|uniprotkb:RNA polymerase II subunit B2(gene name synonym)|uniprotkb:RNA polymerase II subunit 2(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 140 kDa polypeptide(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481001|imex:IM-26985-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057144.1|ensembl:ENSG00000108590(gene)|ensembl:ENST00000225728(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|mint:Q9Y3C7|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 refseq:NP_000929.1|refseq:NP_001290197.1|refseq:NP_001290198.1|ensembl:ENSG00000047315(gene)|ensembl:ENST00000314595(transcript)|ensembl:ENST00000381227(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|mint:P30876|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32910N - - comment:"author score: 52" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRmf6b+uoUOubBcvJbBfl9NgRTQ9606 rogid:YhEjtfLk2QnbRPefOp8ZHX0ejak9606 rigid:jH9tNTkkkEB09CZepHtY/Gt+msA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3C7 uniprotkb:P24928 intact:EBI-394707|uniprotkb:B2R4L9|ensembl:ENSP00000225728 intact:EBI-295301|uniprotkb:A6NN93|uniprotkb:B9EH88|uniprotkb:Q6NX41|intact:EBI-17957133|intact:EBI-14758660|intact:EBI-13324911|intact:EBI-23311874 psi-mi:med31_human(display_long)|uniprotkb:CGI-125(orf name)|uniprotkb:SOH1(gene name synonym)|uniprotkb:MED31(gene name)|psi-mi:MED31(display_short)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:rpb1_human(display_long)|uniprotkb:POLR2A(gene name)|psi-mi:POLR2A(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit A(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:POLR2(gene name synonym)|uniprotkb:RNA-directed RNA polymerase II subunit RPB1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481001|imex:IM-26985-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057144.1|ensembl:ENSG00000108590(gene)|ensembl:ENST00000225728(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|mint:Q9Y3C7|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 refseq:NP_000928.1|mint:P24928|dip:DIP-29011N|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0019900"(kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:2GHQ|rcsb pdb:2GHT|rcsb pdb:2LTO|rcsb pdb:3D9K|rcsb pdb:3D9L|rcsb pdb:3D9M|rcsb pdb:3D9N|rcsb pdb:3D9O|rcsb pdb:3D9P|rcsb pdb:4JXT|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:5M3H|rcsb pdb:5M3J|rcsb pdb:6DRD|rcsb pdb:6F5P|rcsb pdb:6G0R|rcsb pdb:6IC8|rcsb pdb:6IC9|rcsb pdb:6O9L|rcsb pdb:6Q5Y|rcsb pdb:6XKB|rcsb pdb:6XRE|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095 - - comment:"author score: 55" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRmf6b+uoUOubBcvJbBfl9NgRTQ9606 rogid:Si2fgh4AMaNtlzvSQhvsuPusX7s9606 rigid:jH9tNTkkkEB09CZepHtY/Gt+msA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3C7 uniprotkb:Q9BWU1 intact:EBI-394707|uniprotkb:B2R4L9|ensembl:ENSP00000225728 intact:EBI-394593|uniprotkb:Q5JQZ7|uniprotkb:Q5JR00|uniprotkb:Q8TC78|uniprotkb:Q9UPX2|intact:EBI-28987871|ensembl:ENSP00000357907 psi-mi:med31_human(display_long)|uniprotkb:CGI-125(orf name)|uniprotkb:SOH1(gene name synonym)|uniprotkb:MED31(gene name)|psi-mi:MED31(display_short)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:cdk19_human(display_long)|uniprotkb:CDK19(gene name)|psi-mi:CDK19(display_short)|uniprotkb:CDC2-related protein kinase 6(gene name synonym)|uniprotkb:Death-preventing kinase(gene name synonym)|uniprotkb:Cyclin-dependent kinase 11(gene name synonym)|uniprotkb:CDK11(gene name synonym)|uniprotkb:KIAA1028(gene name synonym)|uniprotkb:CDC2L6(gene name synonym)|uniprotkb:Cell division cycle 2-like protein kinase 6(gene name synonym)|uniprotkb:Cell division protein kinase 19(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481001|imex:IM-26985-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057144.1|ensembl:ENSG00000108590(gene)|ensembl:ENST00000225728(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|mint:Q9Y3C7|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 refseq:NP_055891.1|refseq:NP_001287889.1|refseq:NP_001287892.1|refseq:NP_001287893.1|ensembl:ENSG00000155111(gene)|ensembl:ENST00000368911(transcript)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0016592"(mediator complex)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q9BWU1|reactome:R-HSA-1989781|reactome:R-HSA-381340|ensembl:ENST00000323817|ensembl:ENSP00000317665|ensembl:ENSP00000357907|dip:DIP-29013N - - comment:"author score: 56" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRmf6b+uoUOubBcvJbBfl9NgRTQ9606 rogid:80Ngzl9uqRnqMjGnO5v7j72eY7E9606 rigid:jH9tNTkkkEB09CZepHtY/Gt+msA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3C7 uniprotkb:Q9UHV7 intact:EBI-394707|uniprotkb:B2R4L9|ensembl:ENSP00000225728 intact:EBI-394440|uniprotkb:O60334|uniprotkb:B2RU05|ensembl:ENSP00000380888 psi-mi:med31_human(display_long)|uniprotkb:CGI-125(orf name)|uniprotkb:SOH1(gene name synonym)|uniprotkb:MED31(gene name)|psi-mi:MED31(display_short)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:med13_human(display_long)|uniprotkb:TRAP240(gene name synonym)|uniprotkb:MED13(gene name)|psi-mi:MED13(display_short)|uniprotkb:ARC250(gene name synonym)|uniprotkb:KIAA0593(gene name synonym)|uniprotkb:Mediator complex subunit 13(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 240 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 1(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex component DRIP250(gene name synonym)|uniprotkb:Activator-recruited cofactor 250 kDa component(gene name synonym)|uniprotkb:THRAP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481001|imex:IM-26985-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057144.1|ensembl:ENSG00000108590(gene)|ensembl:ENST00000225728(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|mint:Q9Y3C7|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 refseq:NP_005112.2|ensembl:ENSG00000108510(gene)|ensembl:ENST00000397786(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR009401(TRAP240)|interpro:IPR041285|mint:Q9UHV7|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31468N - - comment:"author score: 62" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRmf6b+uoUOubBcvJbBfl9NgRTQ9606 rogid:ZNWwmsetsKLA56joRzRL0UKjq9Y9606 rigid:jH9tNTkkkEB09CZepHtY/Gt+msA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3C7 uniprotkb:Q71F56 intact:EBI-394707|uniprotkb:B2R4L9|ensembl:ENSP00000225728 intact:EBI-394435|uniprotkb:A1L469|uniprotkb:Q68DN4|uniprotkb:Q9H8C0|uniprotkb:Q9NSY9|uniprotkb:Q9UFD8|uniprotkb:Q9UPX5|ensembl:ENSP00000281928 psi-mi:med31_human(display_long)|uniprotkb:CGI-125(orf name)|uniprotkb:SOH1(gene name synonym)|uniprotkb:MED31(gene name)|psi-mi:MED31(display_short)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:md13l_human(display_long)|uniprotkb:Mediator complex subunit 13-like(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 2(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 240 kDa component-like(gene name synonym)|uniprotkb:MED13L(gene name)|psi-mi:MED13L(display_short)|uniprotkb:KIAA1025(gene name synonym)|uniprotkb:PROSIT240(gene name synonym)|uniprotkb:THRAP2(gene name synonym)|uniprotkb:TRAP240L(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481001|imex:IM-26985-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057144.1|ensembl:ENSG00000108590(gene)|ensembl:ENST00000225728(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|mint:Q9Y3C7|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 refseq:NP_056150.1|ensembl:ENSG00000123066(gene)|ensembl:ENST00000281928(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR009401(TRAP240)|interpro:IPR021643|interpro:IPR041285|mint:Q71F56|reactome:R-HSA-1989781|reactome:R-HSA-381340 - - comment:"author score: 69" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRmf6b+uoUOubBcvJbBfl9NgRTQ9606 rogid:Zdj5dM/HEWW8zS27yaXsR+ZOxZs9606 rigid:jH9tNTkkkEB09CZepHtY/Gt+msA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3C7 uniprotkb:P19387 intact:EBI-394707|uniprotkb:B2R4L9|ensembl:ENSP00000225728 intact:EBI-394729|uniprotkb:O15161|ensembl:ENSP00000219252 psi-mi:med31_human(display_long)|uniprotkb:CGI-125(orf name)|uniprotkb:SOH1(gene name synonym)|uniprotkb:MED31(gene name)|psi-mi:MED31(display_short)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:rpb3_human(display_long)|uniprotkb:POLR2C(gene name)|psi-mi:POLR2C(display_short)|uniprotkb:A-152E5.7(orf name)|uniprotkb:DNA-directed RNA polymerase II subunit C(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 33 kDa polypeptide(gene name synonym)|uniprotkb:RPB31(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481001|imex:IM-26985-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057144.1|ensembl:ENSG00000108590(gene)|ensembl:ENST00000225728(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|mint:Q9Y3C7|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 refseq:NP_116558.1|ensembl:ENSG00000102978(gene)|ensembl:ENST00000219252(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001514(DNA-directed RNA polymerase, 30-40 kDa subunit, conserved site)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR036603|interpro:IPR036643|mint:P19387|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32911N - - comment:"author score: 74" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRmf6b+uoUOubBcvJbBfl9NgRTQ9606 rogid:UXFC+i+QqB2WRgL9OiYSQ66L36c9606 rigid:jH9tNTkkkEB09CZepHtY/Gt+msA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3C7 uniprotkb:Q15528 intact:EBI-394707|uniprotkb:B2R4L9|ensembl:ENSP00000225728 intact:EBI-394687|uniprotkb:Q5T8U0|uniprotkb:O76072|uniprotkb:B3KW83|uniprotkb:B3KWX4|ensembl:ENSP00000342343|ensembl:ENSP00000482438|ensembl:ENSP00000485880|ensembl:ENSP00000487580 psi-mi:med31_human(display_long)|uniprotkb:CGI-125(orf name)|uniprotkb:SOH1(gene name synonym)|uniprotkb:MED31(gene name)|psi-mi:MED31(display_short)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:med22_human(display_long)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:MED22(gene name)|psi-mi:MED22(display_short)|uniprotkb:Surfeit locus protein 5(gene name synonym)|uniprotkb:SURF5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481001|imex:IM-26985-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057144.1|ensembl:ENSG00000108590(gene)|ensembl:ENST00000225728(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|mint:Q9Y3C7|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 refseq:NP_598395.1|refseq:NP_852468.1|ensembl:ENSG00000148297(gene)|ensembl:ENSG00000281022(gene)|ensembl:ENST00000343730(transcript)|ensembl:ENST00000610672(transcript)|ensembl:ENST00000629522(transcript)|ensembl:ENST00000631196(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR009332(Surfeit locus 5)|mint:Q15528|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 - - comment:"author score: 91" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRmf6b+uoUOubBcvJbBfl9NgRTQ9606 rogid:bAtK0Srk81ujvVt2Gj0+py7RCZY9606 rigid:jH9tNTkkkEB09CZepHtY/Gt+msA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3C7 uniprotkb:Q93074 intact:EBI-394707|uniprotkb:B2R4L9|ensembl:ENSP00000225728 intact:EBI-394357|uniprotkb:O15410|uniprotkb:O75557|uniprotkb:Q9UHV6|uniprotkb:Q9UND7|ensembl:ENSP00000363193 psi-mi:med31_human(display_long)|uniprotkb:CGI-125(orf name)|uniprotkb:SOH1(gene name synonym)|uniprotkb:MED31(gene name)|psi-mi:MED31(display_short)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:med12_human(display_long)|uniprotkb:TRAP230(gene name synonym)|uniprotkb:MED12(gene name)|psi-mi:MED12(display_short)|uniprotkb:ARC240(gene name synonym)|uniprotkb:CAGH45(gene name synonym)|uniprotkb:HOPA(gene name synonym)|uniprotkb:KIAA0192(gene name synonym)|uniprotkb:Mediator complex subunit 12(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 230 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 240 kDa component(gene name synonym)|uniprotkb:CAG repeat protein 45(gene name synonym)|uniprotkb:OPA-containing protein(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 11 protein(gene name synonym)|uniprotkb:TNRC11(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481001|imex:IM-26985-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057144.1|ensembl:ENSG00000108590(gene)|ensembl:ENST00000225728(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|mint:Q9Y3C7|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 refseq:NP_005111.2|ensembl:ENSG00000184634(gene)|ensembl:ENST00000374080(transcript)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0090245"(axis elongation involved in somitogenesis)|go:"GO:1990403"(embryonic brain development)|interpro:IPR019035|interpro:IPR021989|interpro:IPR021990|mint:Q93074|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0014044"(Schwann cell development)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|dip:DIP-31459N - - comment:"author score: 102" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRmf6b+uoUOubBcvJbBfl9NgRTQ9606 rogid:soNqTi3/n+qnj+P4AX/cPJzTK2U9606 rigid:jH9tNTkkkEB09CZepHtY/Gt+msA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3C7 uniprotkb:O95402 intact:EBI-394707|uniprotkb:B2R4L9|ensembl:ENSP00000225728 intact:EBI-394392|uniprotkb:A1A4S3|uniprotkb:Q0VGB6|intact:EBI-28974475|ensembl:ENSP00000263390 psi-mi:med31_human(display_long)|uniprotkb:CGI-125(orf name)|uniprotkb:SOH1(gene name synonym)|uniprotkb:MED31(gene name)|psi-mi:MED31(display_short)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:med26_human(display_long)|uniprotkb:ARC70(gene name synonym)|uniprotkb:MED26(gene name)|psi-mi:MED26(display_short)|uniprotkb:Mediator complex subunit 26(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 7(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP70(gene name synonym)|uniprotkb:Activator-recruited cofactor 70 kDa component(gene name synonym)|uniprotkb:CRSP7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481001|imex:IM-26985-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057144.1|ensembl:ENSG00000108590(gene)|ensembl:ENST00000225728(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|mint:Q9Y3C7|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 ensembl:ENSP00000263390|ensembl:ENST00000611692|ensembl:ENSP00000484490|refseq:NP_004822.2|ensembl:ENSG00000105085(gene)|ensembl:ENST00000263390(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR017923|interpro:IPR031416|interpro:IPR031417|interpro:IPR035441|interpro:IPR042376|mint:O95402|rcsb pdb:5ODD|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31464N - - comment:"author score: 114" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRmf6b+uoUOubBcvJbBfl9NgRTQ9606 rogid:1kRmQ+QH5uQkKVfjo2Rc2SkAyKc9606 rigid:jH9tNTkkkEB09CZepHtY/Gt+msA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3C7 uniprotkb:Q9BUE0 intact:EBI-394707|uniprotkb:B2R4L9|ensembl:ENSP00000225728 intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184 psi-mi:med31_human(display_long)|uniprotkb:CGI-125(orf name)|uniprotkb:SOH1(gene name synonym)|uniprotkb:MED31(gene name)|psi-mi:MED31(display_short)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481001|imex:IM-26985-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057144.1|ensembl:ENSG00000108590(gene)|ensembl:ENST00000225728(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|mint:Q9Y3C7|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 - - comment:"author score: 118" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRmf6b+uoUOubBcvJbBfl9NgRTQ9606 rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606 rigid:jH9tNTkkkEB09CZepHtY/Gt+msA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3C7 uniprotkb:Q9P086 intact:EBI-394707|uniprotkb:B2R4L9|ensembl:ENSP00000225728 intact:EBI-394704|uniprotkb:Q6NS89|ensembl:ENSP00000293777 psi-mi:med31_human(display_long)|uniprotkb:CGI-125(orf name)|uniprotkb:SOH1(gene name synonym)|uniprotkb:MED31(gene name)|psi-mi:MED31(display_short)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:med11_human(display_long)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:MED11(gene name)|psi-mi:MED11(display_short)|uniprotkb:HSPC296(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481001|imex:IM-26985-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057144.1|ensembl:ENSG00000108590(gene)|ensembl:ENST00000225728(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|mint:Q9Y3C7|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 refseq:NP_001291929.1|refseq:NP_001001683.1|ensembl:ENSG00000161920(gene)|ensembl:ENST00000293777(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019404|mint:Q9P086|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|go:"GO:0003712"(transcription coregulator activity) - - comment:"author score: 133" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRmf6b+uoUOubBcvJbBfl9NgRTQ9606 rogid:y7SZi5hIo5aOatJSZi98Hqt082A9606 rigid:jH9tNTkkkEB09CZepHtY/Gt+msA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3C7 uniprotkb:Q9H944 intact:EBI-394707|uniprotkb:B2R4L9|ensembl:ENSP00000225728 intact:EBI-394644|uniprotkb:Q9Y429|uniprotkb:O95821|uniprotkb:Q5T8J4|uniprotkb:B4DE08|ensembl:ENSP00000265350 psi-mi:med31_human(display_long)|uniprotkb:CGI-125(orf name)|uniprotkb:SOH1(gene name synonym)|uniprotkb:MED31(gene name)|psi-mi:MED31(display_short)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:med20_human(display_long)|uniprotkb:TRFP(gene name synonym)|uniprotkb:MED20(gene name)|psi-mi:MED20(display_short)|uniprotkb:Mediator complex subunit 20(gene name synonym)|uniprotkb:TRF-proximal protein homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481001|imex:IM-26985-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057144.1|ensembl:ENSG00000108590(gene)|ensembl:ENST00000225728(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|mint:Q9Y3C7|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 refseq:NP_004266.2|refseq:NP_001292384.1|refseq:NP_001292385.1|refseq:NP_001292386.1|go:"GO:0016592"(mediator complex)|interpro:IPR013921(TATA-binding related factor)|mint:Q9H944|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000124641(gene)|ensembl:ENST00000265350(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|dip:DIP-31449N - - comment:"author score: 135" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRmf6b+uoUOubBcvJbBfl9NgRTQ9606 rogid:MpYOrONH6+0lKIlO6J+Szjzkw2A9606 rigid:jH9tNTkkkEB09CZepHtY/Gt+msA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3C7 uniprotkb:Q6P2C8 intact:EBI-394707|uniprotkb:B2R4L9|ensembl:ENSP00000225728 intact:EBI-394603|uniprotkb:Q4F964|uniprotkb:O95401|uniprotkb:Q5VTA4|uniprotkb:Q5VTA5|uniprotkb:Q9BU57|uniprotkb:Q9NYR4|uniprotkb:V9GYV9|ensembl:ENSP00000292035 psi-mi:med31_human(display_long)|uniprotkb:CGI-125(orf name)|uniprotkb:SOH1(gene name synonym)|uniprotkb:MED31(gene name)|psi-mi:MED31(display_short)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:med27_human(display_long)|uniprotkb:MED27(gene name)|psi-mi:MED27(display_short)|uniprotkb:Mediator complex subunit 27(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 8(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP34(gene name synonym)|uniprotkb:P37 TRAP/SMCC/PC2 subunit(gene name synonym)|uniprotkb:CRSP34(gene name synonym)|uniprotkb:CRSP8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481001|imex:IM-26985-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057144.1|ensembl:ENSG00000108590(gene)|ensembl:ENST00000225728(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|mint:Q9Y3C7|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 refseq:NP_001240811.1|refseq:NP_004260.2|refseq:NP_001240810.1|dip:DIP-31465N|ensembl:ENSG00000160563(gene)|ensembl:ENST00000292035(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021627|mint:Q6P2C8|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 - - comment:"author score: 143" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRmf6b+uoUOubBcvJbBfl9NgRTQ9606 rogid:V1clNhbtflCzCkC7OnaHGYrmQp89606 rigid:jH9tNTkkkEB09CZepHtY/Gt+msA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3C7 uniprotkb:O75586 intact:EBI-394707|uniprotkb:B2R4L9|ensembl:ENSP00000225728 intact:EBI-394624|uniprotkb:Q6FHQ4|uniprotkb:Q9BTH1|uniprotkb:Q9UHL1|uniprotkb:O15401|uniprotkb:Q53FE3|uniprotkb:Q53HJ3|uniprotkb:B4DU17|uniprotkb:B4E2P0|ensembl:ENSP00000256379 psi-mi:med31_human(display_long)|uniprotkb:CGI-125(orf name)|uniprotkb:SOH1(gene name synonym)|uniprotkb:MED31(gene name)|psi-mi:MED31(display_short)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:med6_human(display_long)|uniprotkb:ARC33(gene name synonym)|uniprotkb:MED6(gene name)|psi-mi:MED6(display_short)|uniprotkb:Mediator complex subunit 6(gene name synonym)|uniprotkb:Activator-recruited cofactor 33 kDa component(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-28(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481001|imex:IM-26985-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057144.1|ensembl:ENSG00000108590(gene)|ensembl:ENST00000225728(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|mint:Q9Y3C7|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 refseq:NP_005457.2|refseq:NP_001271138.1|refseq:NP_001271139.1|refseq:NP_001271140.1|ensembl:ENSG00000133997(gene)|ensembl:ENST00000256379(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR007018(MED6 mediator)|interpro:IPR016820(Mediator complex, subunit 6, metazoa/plant)|interpro:IPR038566|mint:O75586|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31456N - - comment:"author score: 145" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRmf6b+uoUOubBcvJbBfl9NgRTQ9606 rogid:QYK+2tX/HC1OGGPu3b3S1v/ODR89606 rigid:jH9tNTkkkEB09CZepHtY/Gt+msA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3C7 uniprotkb:Q9NVC6 intact:EBI-394707|uniprotkb:B2R4L9|ensembl:ENSP00000225728 intact:EBI-394562|uniprotkb:Q9HA81|uniprotkb:Q9UNP7|uniprotkb:Q9Y2W0|uniprotkb:Q9Y660|uniprotkb:B3KN07|ensembl:ENSP00000251871 psi-mi:med31_human(display_long)|uniprotkb:CGI-125(orf name)|uniprotkb:SOH1(gene name synonym)|uniprotkb:MED31(gene name)|psi-mi:MED31(display_short)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:med17_human(display_long)|uniprotkb:TRAP80(gene name synonym)|uniprotkb:MED17(gene name)|psi-mi:MED17(display_short)|uniprotkb:ARC77(gene name synonym)|uniprotkb:DRIP80(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 6(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP77(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 80 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 80 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 77 kDa component(gene name synonym)|uniprotkb:CRSP6(gene name synonym)|uniprotkb:DRIP77(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481001|imex:IM-26985-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057144.1|ensembl:ENSG00000108590(gene)|ensembl:ENST00000225728(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|mint:Q9Y3C7|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 refseq:NP_004259.3|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|ensembl:ENSG00000042429(gene)|ensembl:ENST00000251871(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019313|mint:Q9NVC6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31451N - - comment:"author score: 147" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRmf6b+uoUOubBcvJbBfl9NgRTQ9606 rogid:P2hRQOjWEtjw5V+lt7J9TP3VbpU9606 rigid:jH9tNTkkkEB09CZepHtY/Gt+msA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3C7 uniprotkb:Q9H204 intact:EBI-394707|uniprotkb:B2R4L9|ensembl:ENSP00000225728 intact:EBI-514199|uniprotkb:Q9BZJ5|ensembl:ENSP00000237380 psi-mi:med31_human(display_long)|uniprotkb:CGI-125(orf name)|uniprotkb:SOH1(gene name synonym)|uniprotkb:MED31(gene name)|psi-mi:MED31(display_short)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:med28_human(display_long)|uniprotkb:Mediator complex subunit 28(gene name synonym)|uniprotkb:Tumor angiogenesis marker EG-1(gene name synonym)|uniprotkb:Endothelial-derived protein 1(gene name synonym)|uniprotkb:Merlin and Grb2-interacting cytoskeletal protein(gene name synonym)|uniprotkb:MED28(gene name)|psi-mi:MED28(display_short)|uniprotkb:EG1(gene name synonym)|uniprotkb:FKSG20(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481001|imex:IM-26985-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057144.1|ensembl:ENSG00000108590(gene)|ensembl:ENST00000225728(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|mint:Q9Y3C7|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 refseq:NP_079481.2|ensembl:ENSG00000118579(gene)|ensembl:ENST00000237380(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0051151"(negative regulation of smooth muscle cell differentiation)|interpro:IPR021640|mint:Q9H204|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 - - comment:"author score: 147" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRmf6b+uoUOubBcvJbBfl9NgRTQ9606 rogid:1gt/0vP7vWJ+M1fU+qZPcWGj34U9606 rigid:jH9tNTkkkEB09CZepHtY/Gt+msA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3C7 uniprotkb:Q96G25 intact:EBI-394707|uniprotkb:B2R4L9|ensembl:ENSP00000225728 intact:EBI-394405|uniprotkb:A9IZ91|uniprotkb:Q96FQ4|uniprotkb:A9IZ92|uniprotkb:Q5JUY8|ensembl:ENSP00000361535 psi-mi:med31_human(display_long)|uniprotkb:CGI-125(orf name)|uniprotkb:SOH1(gene name synonym)|uniprotkb:MED31(gene name)|psi-mi:MED31(display_short)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:med8_human(display_long)|uniprotkb:MED8(gene name)|psi-mi:MED8(display_short)|uniprotkb:Mediator complex subunit 8(gene name synonym)|uniprotkb:Activator-recruited cofactor 32 kDa component(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481001|imex:IM-26985-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057144.1|ensembl:ENSG00000108590(gene)|ensembl:ENST00000225728(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|mint:Q9Y3C7|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 refseq:NP_443109.2|refseq:NP_963836.2|refseq:NP_001001653.1|ensembl:ENSG00000159479(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|mint:Q96G25|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENST00000372457(transcript) - - comment:"author score: 156" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRmf6b+uoUOubBcvJbBfl9NgRTQ9606 rogid:e/ye7rfa2E1XOPb5vVhI9Nvqmxw9606 rigid:jH9tNTkkkEB09CZepHtY/Gt+msA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3C7 uniprotkb:Q15648 intact:EBI-394707|uniprotkb:B2R4L9|ensembl:ENSP00000225728 intact:EBI-394459|uniprotkb:A2RRQ6|uniprotkb:O43810|uniprotkb:O75447|uniprotkb:Q6P9H7|uniprotkb:Q6PK58|uniprotkb:Q9HD39|ensembl:ENSP00000300651 psi-mi:med31_human(display_long)|uniprotkb:CGI-125(orf name)|uniprotkb:SOH1(gene name synonym)|uniprotkb:MED31(gene name)|psi-mi:MED31(display_short)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:med1_human(display_long)|uniprotkb:TRIP2(gene name synonym)|uniprotkb:MED1(gene name)|psi-mi:MED1(display_short)|uniprotkb:ARC205(gene name synonym)|uniprotkb:DRIP205(gene name synonym)|uniprotkb:TRAP220(gene name synonym)|uniprotkb:Activator-recruited cofactor 205 kDa component(gene name synonym)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-binding protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 220 kDa component(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 2(gene name synonym)|uniprotkb:p53 regulatory protein RB18A(gene name synonym)|uniprotkb:Vitamin D receptor-interacting protein complex component DRIP205(gene name synonym)|uniprotkb:CRSP1(gene name synonym)|uniprotkb:CRSP200(gene name synonym)|uniprotkb:DRIP230(gene name synonym)|uniprotkb:PBP(gene name synonym)|uniprotkb:PPARBP(gene name synonym)|uniprotkb:PPARGBP(gene name synonym)|uniprotkb:RB18A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481001|imex:IM-26985-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057144.1|ensembl:ENSG00000108590(gene)|ensembl:ENST00000225728(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|mint:Q9Y3C7|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 refseq:NP_004765.2|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR019680|mint:Q15648|rcsb pdb:1RJK|rcsb pdb:1RK3|rcsb pdb:1RKG|rcsb pdb:1RKH|rcsb pdb:2O4J|rcsb pdb:2O4R|rcsb pdb:2ZFX|rcsb pdb:3A2H|rcsb pdb:3AUN|rcsb pdb:3VJS|rcsb pdb:3VJT|rcsb pdb:3VRT|rcsb pdb:3VRU|rcsb pdb:3VRV|rcsb pdb:3VRW|rcsb pdb:3W0G|rcsb pdb:3W0H|rcsb pdb:3W0I|rcsb pdb:3W0J|rcsb pdb:3W5P|rcsb pdb:3W5Q|rcsb pdb:3W5R|rcsb pdb:3W5T|rcsb pdb:3WT5|rcsb pdb:3WT6|rcsb pdb:3WT7|rcsb pdb:3WTQ|rcsb pdb:4YNK|rcsb pdb:5AWJ|rcsb pdb:5AWK|rcsb pdb:5B41|rcsb pdb:5B5B|rcsb pdb:5GIC|rcsb pdb:5GID|rcsb pdb:5GIE|rcsb pdb:5XPM|rcsb pdb:5XPN|rcsb pdb:5XPO|rcsb pdb:5XPP|rcsb pdb:5XUQ|rcsb pdb:5XZF|rcsb pdb:5XZH|rcsb pdb:5ZWE|rcsb pdb:5ZWF|rcsb pdb:5ZWH|rcsb pdb:5ZWI|rcsb pdb:6D94|rcsb pdb:6JEZ|rcsb pdb:6K5O|rcsb pdb:6ONJ|rcsb pdb:7C7V|rcsb pdb:7C7W|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9707564|reactome:R-HSA-9707616|ensembl:ENSG00000125686(gene)|ensembl:ENST00000300651(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003406"(retinal pigment epithelium development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0050693"(LBD domain binding)|dip:DIP-24212N - - comment:"author score: 167" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRmf6b+uoUOubBcvJbBfl9NgRTQ9606 rogid:A4EIAri9zYycSlTA7s6NzbOi9n49606 rigid:jH9tNTkkkEB09CZepHtY/Gt+msA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3C7 uniprotkb:O60244 intact:EBI-394707|uniprotkb:B2R4L9|ensembl:ENSP00000225728 intact:EBI-394489|uniprotkb:Q4KMR7|uniprotkb:Q9UNB3|ensembl:ENSP00000323720 psi-mi:med31_human(display_long)|uniprotkb:CGI-125(orf name)|uniprotkb:SOH1(gene name synonym)|uniprotkb:MED31(gene name)|psi-mi:MED31(display_short)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:med14_human(display_long)|uniprotkb:TRAP170(gene name synonym)|uniprotkb:MED14(gene name)|psi-mi:MED14(display_short)|uniprotkb:ARC150(gene name synonym)|uniprotkb:DRIP150(gene name synonym)|uniprotkb:EXLM1(gene name synonym)|uniprotkb:RGR1(gene name synonym)|uniprotkb:Mediator complex subunit 14(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 2(gene name synonym)|uniprotkb:RGR1 homolog(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP150(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 150 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 170 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 150 kDa component(gene name synonym)|uniprotkb:CRSP2(gene name synonym)|uniprotkb:CXorf4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481001|imex:IM-26985-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057144.1|ensembl:ENSG00000108590(gene)|ensembl:ENST00000225728(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|mint:Q9Y3C7|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 refseq:NP_004220.2|ensembl:ENSG00000180182(gene)|ensembl:ENST00000324817(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR013947(Mediator complex, subunit MED14)|mint:O60244|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31460N - - comment:"author score: 171" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRmf6b+uoUOubBcvJbBfl9NgRTQ9606 rogid:73RBAnwmB4Lyl/kcsg7NKSUmA4c9606 rigid:jH9tNTkkkEB09CZepHtY/Gt+msA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3C7 uniprotkb:A0JLT2 intact:EBI-394707|uniprotkb:B2R4L9|ensembl:ENSP00000225728 intact:EBI-394430|uniprotkb:Q8IV02|intact:EBI-394763|uniprotkb:Q8IZD1 psi-mi:med31_human(display_long)|uniprotkb:CGI-125(orf name)|uniprotkb:SOH1(gene name synonym)|uniprotkb:MED31(gene name)|psi-mi:MED31(display_short)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:med19_human(display_long)|uniprotkb:MED19(gene name)|psi-mi:MED19(display_short)|uniprotkb:LCMR1(gene name synonym)|uniprotkb:Lung cancer metastasis-related protein 1(gene name synonym)|uniprotkb:Mediator complex subunit 19(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481001|imex:IM-26985-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057144.1|ensembl:ENSG00000108590(gene)|ensembl:ENST00000225728(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|mint:Q9Y3C7|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 refseq:NP_001304007.1|refseq:NP_703151.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR019403|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|mint:A0JLT2|dip:DIP-31467N - - comment:"author score: 179" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRmf6b+uoUOubBcvJbBfl9NgRTQ9606 rogid:zcHhU2hQvuTpkFZz/xEKYmjrwOA9606 rigid:jH9tNTkkkEB09CZepHtY/Gt+msA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3C7 uniprotkb:Q9NWA0 intact:EBI-394707|uniprotkb:B2R4L9|ensembl:ENSP00000225728 intact:EBI-394653|ensembl:ENSP00000268711 psi-mi:med31_human(display_long)|uniprotkb:CGI-125(orf name)|uniprotkb:SOH1(gene name synonym)|uniprotkb:MED31(gene name)|psi-mi:MED31(display_short)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:med9_human(display_long)|uniprotkb:MED9(gene name)|psi-mi:MED9(display_short)|uniprotkb:Mediator complex subunit 9(gene name synonym)|uniprotkb:MED25(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481001|imex:IM-26985-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057144.1|ensembl:ENSG00000108590(gene)|ensembl:ENST00000225728(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|mint:Q9Y3C7|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 refseq:NP_060489.1|ensembl:ENSG00000141026(gene)|ensembl:ENST00000268711(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR011425(RNA polymerase II transcription mediator)|interpro:IPR037212|interpro:IPR039242|mint:Q9NWA0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 - - comment:"author score: 179" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRmf6b+uoUOubBcvJbBfl9NgRTQ9606 rogid:VSYpA1Aqh2FEaZIEF/6iCIpoPEc9606 rigid:jH9tNTkkkEB09CZepHtY/Gt+msA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3C7 uniprotkb:Q9BTT4 intact:EBI-394707|uniprotkb:B2R4L9|ensembl:ENSP00000225728 intact:EBI-394354|uniprotkb:C6G491|ensembl:ENSP00000255764 psi-mi:med31_human(display_long)|uniprotkb:CGI-125(orf name)|uniprotkb:SOH1(gene name synonym)|uniprotkb:MED31(gene name)|psi-mi:MED31(display_short)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:med10_human(display_long)|uniprotkb:MED10(gene name)|psi-mi:MED10(display_short)|uniprotkb:L6(orf name)|uniprotkb:TRG17(orf name)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Transformation-related gene 17 protein(gene name synonym)|uniprotkb:Transformation-related gene 20 protein(gene name synonym)|uniprotkb:TRG20(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481001|imex:IM-26985-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057144.1|ensembl:ENSG00000108590(gene)|ensembl:ENST00000225728(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|mint:Q9Y3C7|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 ensembl:ENSG00000133398(gene)|ensembl:ENST00000255764(transcript)|refseq:NP_115662.2|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019145|mint:Q9BTT4|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|go:"GO:0000151"(ubiquitin ligase complex)|dip:DIP-31457N - - comment:"author score: 190" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRmf6b+uoUOubBcvJbBfl9NgRTQ9606 rogid:LzJW7C8kl2pWmffOjo8S/FNSS9I9606 rigid:jH9tNTkkkEB09CZepHtY/Gt+msA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3C7 uniprotkb:Q9NPJ6 intact:EBI-394707|uniprotkb:B2R4L9|ensembl:ENSP00000225728 intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648 psi-mi:med31_human(display_long)|uniprotkb:CGI-125(orf name)|uniprotkb:SOH1(gene name synonym)|uniprotkb:MED31(gene name)|psi-mi:MED31(display_short)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481001|imex:IM-26985-39 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057144.1|ensembl:ENSG00000108590(gene)|ensembl:ENST00000225728(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|mint:Q9Y3C7|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 - - comment:"author score: 215" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRmf6b+uoUOubBcvJbBfl9NgRTQ9606 rogid:Bept2Oec50gruA9e4pf+eEUiANM9606 rigid:jH9tNTkkkEB09CZepHtY/Gt+msA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43513 uniprotkb:Q5T9A4 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-1384144|uniprotkb:Q6ZRB5|uniprotkb:Q9BUK4|uniprotkb:Q9ULE7|uniprotkb:A8K3H1|ensembl:ENSP00000500094 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:atd3b_human(display_long)|uniprotkb:TOB3(gene name synonym)|uniprotkb:AAA-TOB3(gene name synonym)|uniprotkb:KIAA1273(gene name synonym)|uniprotkb:ATAD3B(gene name)|psi-mi:ATAD3B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481112|imex:IM-26985-337 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM refseq:NP_114127.3|refseq:NP_001304167.1|ensembl:ENSG00000160072(gene)|ensembl:ENST00000673477(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR021911|interpro:IPR027417|interpro:IPR039188|mint:Q5T9A4|reactome:R-HSA-6798695 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:2W52iPQhTBU2apShm8xhfenV1mU9606 rigid:fkTGen4snam1YYN5NZM6kE3hSL8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43513 uniprotkb:P0CAP2 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-9657655|uniprotkb:Q96NF5|uniprotkb:Q6EFN8|uniprotkb:Q6EEV3|uniprotkb:Q9Y3V6|uniprotkb:Q8NC58|uniprotkb:Q96DI5|uniprotkb:Q6EF02|uniprotkb:Q6K050|uniprotkb:Q6K046|uniprotkb:Q6K051|uniprotkb:Q6EF01|uniprotkb:Q6EES2|uniprotkb:Q8NCF3|uniprotkb:Q6EM48|uniprotkb:Q6EF46|uniprotkb:Q6ZQZ3|uniprotkb:Q6EER8|uniprotkb:Q96JB7|uniprotkb:Q6EF00|ensembl:ENSP00000299638 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:grl1a_human(display_long)|uniprotkb:POLR2M(gene name)|psi-mi:POLR2M(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit M(gene name synonym)|uniprotkb:GRINL1A(gene name synonym)|uniprotkb:Glutamate receptor-like protein 1A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481112|imex:IM-26985-337 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM refseq:NP_001018112.1|refseq:NP_056347.1|dip:DIP-61933N|ensembl:ENSG00000255529(gene)|ensembl:ENST00000299638(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051685"(maintenance of ER location)|interpro:IPR026213|mint:P0CAP2|rcsb pdb:6DRD - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:G0QVxeD0uvJTl0VPn+b3pV6zLe89606 rigid:fkTGen4snam1YYN5NZM6kE3hSL8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43513 uniprotkb:Q9ULK4 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-311161|uniprotkb:Q5JWT3|uniprotkb:Q5JWT4|uniprotkb:Q6P9H6|uniprotkb:O95403|uniprotkb:Q9H0J2|uniprotkb:Q9NTT9|uniprotkb:Q9NTU0|uniprotkb:Q9Y5P7|uniprotkb:Q9Y667|ensembl:ENSP00000357047|uniprotkb:B9TX55 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:med23_human(display_long)|uniprotkb:MED23(gene name)|psi-mi:MED23(display_short)|uniprotkb:ARC130(gene name synonym)|uniprotkb:DRIP130(gene name synonym)|uniprotkb:KIAA1216(gene name synonym)|uniprotkb:SUR2(gene name synonym)|uniprotkb:CRSP3(gene name synonym)|uniprotkb:Mediator complex subunit 23(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 3(gene name synonym)|uniprotkb:Protein sur-2 homolog(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP130(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 130 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 130 kDa component(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481112|imex:IM-26985-337 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM refseq:NP_057063.2|refseq:NP_004821.2|ensembl:ENSG00000112282(gene)|ensembl:ENST00000368068(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016592"(mediator complex)|interpro:IPR021629|mint:Q9ULK4|rcsb pdb:6H02|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001257450.1|refseq:NP_001257451.1|dip:DIP-31461N - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:gO5TvUnko3zY/83OHbeVmh7b+f89606 rigid:fkTGen4snam1YYN5NZM6kE3hSL8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43513 uniprotkb:Q6F5E8 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-9513063|uniprotkb:B8X2Z3|ensembl:ENSP00000334958 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:carl2_human(display_long)|uniprotkb:CARMIL2(gene name)|psi-mi:CARMIL2(display_short)|uniprotkb:Capping protein regulator and myosin 1 linker 2(gene name synonym)|uniprotkb:F-actin-uncapping protein RLTPR(gene name synonym)|uniprotkb:LRRC16C(gene name synonym)|uniprotkb:Leucine-rich repeat-containing protein 16C(gene name synonym)|uniprotkb:RGD, leucine-rich repeat, tropomodulin and proline-rich-containing protein(gene name synonym)|uniprotkb:RLTPR(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481112|imex:IM-26985-337 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM refseq:NP_001303955.1|refseq:NP_001013860.1|ensembl:ENSG00000159753(gene)|ensembl:ENST00000334583(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031252"(cell leading edge)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0044354"(macropinosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051639"(actin filament network formation)|go:"GO:0061339"(establishment or maintenance of monopolar cell polarity)|go:"GO:0090091"(positive regulation of extracellular matrix disassembly)|go:"GO:1900029"(positive regulation of ruffle assembly)|go:"GO:1902745"(positive regulation of lamellipodium organization)|go:"GO:2000813"(negative regulation of barbed-end actin filament capping)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029763|interpro:IPR031943|interpro:IPR041245|mint:Q6F5E8 - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:gAT9BXBiOtVtPa/z6R0XqY0/H/49606 rigid:fkTGen4snam1YYN5NZM6kE3hSL8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43513 uniprotkb:Q8IXW5 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-395878|uniprotkb:Q49AS7|uniprotkb:Q9H8Y2|ensembl:ENSP00000476948|uniprotkb:C9JKB5 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:rpap2_human(display_long)|uniprotkb:RPAP2(gene name)|psi-mi:RPAP2(display_short)|uniprotkb:C1orf82(gene name synonym)|uniprotkb:RNA polymerase II-associated protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481112|imex:IM-26985-337 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM refseq:NP_079089.2|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008420"(RNA polymerase II CTD heptapeptide repeat phosphatase activity)|go:"GO:0009301"(snRNA transcription)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0043175"(RNA polymerase core enzyme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR007308(Protein of unknown function DUF408)|interpro:IPR038534|interpro:IPR039693|mint:Q8IXW5|rcsb pdb:7B7U|reactome:R-HSA-6807505|ensembl:ENSG00000122484(gene)|ensembl:ENST00000610020(transcript)|go:"GO:0005634"(nucleus)|dip:DIP-32939N - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:niEFEvqkASycxkzfe9TYJuerUuY9606 rigid:fkTGen4snam1YYN5NZM6kE3hSL8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43513 uniprotkb:Q9Y2X0 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-394541|uniprotkb:Q6PJT2|uniprotkb:Q96AD4|uniprotkb:Q96I35|uniprotkb:Q9Y652|ensembl:ENSP00000325612 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:med16_human(display_long)|uniprotkb:MED16(gene name)|psi-mi:MED16(display_short)|uniprotkb:Mediator complex subunit 16(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 95 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 5(gene name synonym)|uniprotkb:DRIP92(gene name synonym)|uniprotkb:THRAP5(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 92 kDa component(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481112|imex:IM-26985-337 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM refseq:NP_005472.2|ensembl:ENSG00000175221(gene)|ensembl:ENST00000325464(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR001680(WD40 repeat)|interpro:IPR011041(Soluble quinoprotein glucose dehydrogenase)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR021665|interpro:IPR036322|mint:Q9Y2X0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31463N - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:nMHDmIPhzAalahGVVsO++rpQE/U9606 rigid:fkTGen4snam1YYN5NZM6kE3hSL8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43513 uniprotkb:O75448 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-394523|uniprotkb:Q14143|uniprotkb:Q9NNY5|uniprotkb:A8K4S5|uniprotkb:B3KMR9|ensembl:ENSP00000377686 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:med24_human(display_long)|uniprotkb:TRAP100(gene name synonym)|uniprotkb:MED24(gene name)|psi-mi:MED24(display_short)|uniprotkb:DRIP100(gene name synonym)|uniprotkb:KIAA0130(gene name synonym)|uniprotkb:Mediator complex subunit 24(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 100 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 100 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 100 kDa component(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 4(gene name synonym)|uniprotkb:ARC100(gene name synonym)|uniprotkb:CRSP4(gene name synonym)|uniprotkb:THRAP4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481112|imex:IM-26985-337 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM refseq:XP_016880955.1|refseq:NP_001072986.1|refseq:NP_055630.2|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021429|mint:O75448|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000008838(gene)|ensembl:ENST00000394128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|refseq:NP_001254726.1|dip:DIP-31462N - - comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:H0iGOXcj8Qe1FOU7pOXkhaAS+pc9606 rigid:fkTGen4snam1YYN5NZM6kE3hSL8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43513 uniprotkb:P62487 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-347928|ensembl:ENSP00000301788|uniprotkb:P52433|uniprotkb:Q2M1Z4|uniprotkb:B2R5C0 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:rpb7_human(display_long)|uniprotkb:POLR2G(gene name)|psi-mi:POLR2G(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit G(gene name synonym)|uniprotkb:RPB7(gene name synonym)|uniprotkb:RNA polymerase II 19 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481112|imex:IM-26985-337 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM ensembl:ENSG00000168002(gene)|ensembl:ENST00000301788(transcript)|go:"GO:0000291"(nuclear-transcribed mRNA catabolic process, exonucleolytic)|go:"GO:0000932"(P-body)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006915"(apoptotic process)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR003029(S1, RNA binding)|interpro:IPR005576(RNA polymerase Rpb7, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR036898|mint:P62487|rcsb pdb:2C35|rcsb pdb:5IYA|rcsb pdb:5IY6|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|rcsb pdb:5IY7|reactome:R-HSA-167200|reactome:R-HSA-167238|rcsb pdb:5IY8|rcsb pdb:5IY9|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-5601884|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|refseq:NP_002687.1|dip:DIP-32663N - - comment:"author score: 27" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:MtnIweuhSqLFov0c40uOiwv8Eas9606 rigid:fkTGen4snam1YYN5NZM6kE3hSL8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43513 uniprotkb:Q86YW9 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-3957138|uniprotkb:Q96PC7|uniprotkb:Q96PC8|uniprotkb:Q9H9M5|uniprotkb:Q9HCD7|uniprotkb:Q9UI69|ensembl:ENSP00000417235 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:md12l_human(display_long)|uniprotkb:MED12L(gene name)|psi-mi:MED12L(display_short)|uniprotkb:KIAA1635(gene name synonym)|uniprotkb:TNRC11L(gene name synonym)|uniprotkb:TRALP(gene name synonym)|uniprotkb:TRALPUSH(gene name synonym)|uniprotkb:Mediator complex subunit 12-like protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated-like protein(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 11 protein-like(gene name synonym)|uniprotkb:PRO0314(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481112|imex:IM-26985-337 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM refseq:XP_011510692.1|refseq:NP_443728.3|ensembl:ENST00000309237|ensembl:ENSP00000310760|ensembl:ENST00000422248|ensembl:ENSP00000403308|ensembl:ENSP00000417235|ensembl:ENSG00000144893(gene)|ensembl:ENST00000474524(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016592"(mediator complex)|interpro:IPR019035|interpro:IPR021989|interpro:IPR021990|mint:Q86YW9 - - comment:"author score: 30" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:85LCBTAduFNnKfHO0S10ocwWXyE9606 rigid:fkTGen4snam1YYN5NZM6kE3hSL8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43513 uniprotkb:Q96RN5 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-394506|uniprotkb:O15413|uniprotkb:Q6IC31|uniprotkb:Q8NF16|uniprotkb:Q96CT0|uniprotkb:Q96IH7|uniprotkb:Q9P1T3|uniprotkb:D3DX31|uniprotkb:D3DX32|ensembl:ENSP00000263205 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:med15_human(display_long)|uniprotkb:MED15(gene name)|psi-mi:MED15(display_short)|uniprotkb:ARC105(gene name synonym)|uniprotkb:CTG7A(gene name synonym)|uniprotkb:Mediator complex subunit 15(gene name synonym)|uniprotkb:Positive cofactor 2 glutamine/Q-rich-associated protein(gene name synonym)|uniprotkb:TPA-inducible gene 1 protein(gene name synonym)|uniprotkb:Activator-recruited cofactor 105 kDa component(gene name synonym)|uniprotkb:CTG repeat protein 7a(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 7 protein(gene name synonym)|uniprotkb:TIG1(gene name synonym)|uniprotkb:PCQAP(gene name synonym)|uniprotkb:TNRC7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481112|imex:IM-26985-337 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM refseq:NP_001280164.1|refseq:NP_001280165.1|refseq:NP_001003891.1|refseq:NP_056973.2|ensembl:ENSG00000099917(gene)|ensembl:ENST00000263205(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|interpro:IPR019087|interpro:IPR036529|mint:Q96RN5|rcsb pdb:2GUT|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-32908N - - comment:"author score: 34" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:8dqqSCXYc7Bp56sjogz0jpbTQLI9606 rigid:fkTGen4snam1YYN5NZM6kE3hSL8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43513 uniprotkb:Q709F0 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-2880718|ensembl:ENSP00000264990|uniprotkb:Q8WUT6|uniprotkb:Q08AF0|uniprotkb:Q658Y2|uniprotkb:Q658N9|uniprotkb:Q6ZND2|uniprotkb:Q9H9R3 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:acd11_human(display_long)|uniprotkb:ACAD11(gene name)|psi-mi:ACAD11(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481112|imex:IM-26985-337 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM ensembl:ENSG00000240303(gene)|ensembl:ENST00000264990(transcript)|go:"GO:0003995"(acyl-CoA dehydrogenase activity)|go:"GO:0004466"(long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0017099"(very-long-chain-acyl-CoA dehydrogenase activity)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0033539"(fatty acid beta-oxidation using acyl-CoA dehydrogenase)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0070991"(medium-chain-acyl-CoA dehydrogenase activity)|interpro:IPR002575(Aminoglycoside phosphotransferase)|interpro:IPR009075(Acyl-CoA dehydrogenase/oxidase C-terminal)|interpro:IPR009100(Acyl-CoA dehydrogenase/oxidase, middle and N-terminal)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013786(Acyl-CoA dehydrogenase/oxidase, N-terminal)|interpro:IPR036250|interpro:IPR037069|interpro:IPR041726|mint:Q709F0|rcsb pdb:2WBI|reactome:R-HSA-77289|interpro:IPR006091(Acyl-CoA dehydrogenase/oxidase, central region)|refseq:NP_115545.3 - - comment:"author score: 34" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:Qknz1ZNcvX0q/3f5TuGQkJ6oHSk9606 rigid:fkTGen4snam1YYN5NZM6kE3hSL8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43513 uniprotkb:Q9NX70 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-394656|uniprotkb:Q9NTF4|uniprotkb:Q5XX09|uniprotkb:B4DNQ6|uniprotkb:M0R2E4|ensembl:ENSP00000314343 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:med29_human(display_long)|uniprotkb:MED29(gene name)|psi-mi:MED29(display_short)|uniprotkb:Mediator complex subunit 29(gene name synonym)|uniprotkb:Intersex-like protein(gene name synonym)|uniprotkb:IXL(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481112|imex:IM-26985-337 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM refseq:NP_060062.1|refseq:NP_001304699.1|ensembl:ENSG00000063322(gene)|ensembl:ENST00000315588(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR021018|mint:Q9NX70|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|reactome:R-HSA-1989781|reactome:R-HSA-381340 - - comment:"author score: 41" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:WOrt3DAoOape6p0CwWSLIW55hVg9606 rigid:fkTGen4snam1YYN5NZM6kE3hSL8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43513 uniprotkb:Q9BWU1 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-394593|uniprotkb:Q5JQZ7|uniprotkb:Q5JR00|uniprotkb:Q8TC78|uniprotkb:Q9UPX2|intact:EBI-28987871|ensembl:ENSP00000357907 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:cdk19_human(display_long)|uniprotkb:CDK19(gene name)|psi-mi:CDK19(display_short)|uniprotkb:CDC2-related protein kinase 6(gene name synonym)|uniprotkb:Death-preventing kinase(gene name synonym)|uniprotkb:Cyclin-dependent kinase 11(gene name synonym)|uniprotkb:CDK11(gene name synonym)|uniprotkb:KIAA1028(gene name synonym)|uniprotkb:CDC2L6(gene name synonym)|uniprotkb:Cell division cycle 2-like protein kinase 6(gene name synonym)|uniprotkb:Cell division protein kinase 19(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481112|imex:IM-26985-337 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM refseq:NP_055891.1|refseq:NP_001287889.1|refseq:NP_001287892.1|refseq:NP_001287893.1|ensembl:ENSG00000155111(gene)|ensembl:ENST00000368911(transcript)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0016592"(mediator complex)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q9BWU1|reactome:R-HSA-1989781|reactome:R-HSA-381340|ensembl:ENST00000323817|ensembl:ENSP00000317665|ensembl:ENSP00000357907|dip:DIP-29013N - - comment:"author score: 48" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:80Ngzl9uqRnqMjGnO5v7j72eY7E9606 rigid:fkTGen4snam1YYN5NZM6kE3hSL8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43513 uniprotkb:P52434 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-359505|uniprotkb:P53802|uniprotkb:Q969R0|ensembl:ENSP00000392913|uniprotkb:C9J413|uniprotkb:C9JBJ6|uniprotkb:C9JCU7|uniprotkb:C9JUA8 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:rpab3_human(display_long)|uniprotkb:POLR2H(gene name)|psi-mi:POLR2H(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit H(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I, II, and III 17.1 kDa polypeptide(gene name synonym)|uniprotkb:RPB17(gene name synonym)|uniprotkb:RPB8 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481112|imex:IM-26985-337 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM ensembl:ENSG00000163882(gene)|ensembl:ENST00000456318(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032993"(protein-DNA complex)|interpro:IPR005570(RNA polymerase, Rpb8)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:P52434|rcsb pdb:2F3I|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|refseq:NP_006223.2|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|rcsb pdb:7AE3|reactome:R-HSA-1834949|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-427413|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-203927|refseq:NP_001265627.1|refseq:NP_001265628.1|refseq:NP_001265629.1|refseq:NP_001265644.1|refseq:NP_001265643.1|refseq:XP_006713729.1|refseq:XP_006713730.1|refseq:XP_016862125.1|refseq:XP_016862126.1|dip:DIP-27556N - - comment:"author score: 50" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:h7BRWDi8wRbnw/FcFo25bnlVNkE9606 rigid:fkTGen4snam1YYN5NZM6kE3hSL8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43513 uniprotkb:P24863 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-395261|uniprotkb:Q9H543|ensembl:ENSP00000428982|uniprotkb:B4DPZ1 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:ccnc_human(display_long)|uniprotkb:CCNC(gene name)|psi-mi:CCNC(display_short)|uniprotkb:SRB11 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481112|imex:IM-26985-337 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM ensembl:ENSG00000112237(gene)|ensembl:ENST00000520429(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR028367|interpro:IPR036915|interpro:IPR043198|mint:P24863|rcsb pdb:5XQX|rcsb pdb:5XS2|rcsb pdb:6QTG|rcsb pdb:6QTJ|rcsb pdb:6R3S|rcsb pdb:6T41|rcsb pdb:6TPA|rcsb pdb:6Y0A|reactome:R-HSA-1989781|reactome:R-HSA-2122947|reactome:R-HSA-212436|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-381340|rcsb pdb:3RGF|rcsb pdb:4CRL|rcsb pdb:4F6S|rcsb pdb:4F6U|rcsb pdb:4F6W|rcsb pdb:4F70|rcsb pdb:4F7J|rcsb pdb:4F7L|rcsb pdb:4F7N|rcsb pdb:4F7S|rcsb pdb:4G6L|rcsb pdb:5BNJ|rcsb pdb:5CEI|rcsb pdb:5FGK|rcsb pdb:5HBE|rcsb pdb:5HBH|rcsb pdb:5HBJ|rcsb pdb:5HNB|rcsb pdb:5HVY|rcsb pdb:5I5Z|rcsb pdb:5ICP|rcsb pdb:5IDN|rcsb pdb:5IDP|refseq:NP_005181.2|refseq:NP_001013417.1|dip:DIP-32920N - - comment:"author score: 57" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:Gu327q98H8ggQoYCb4UnR2Mcsyg9606 rigid:fkTGen4snam1YYN5NZM6kE3hSL8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43513 uniprotkb:Q9UHV7 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-394440|uniprotkb:O60334|uniprotkb:B2RU05|ensembl:ENSP00000380888 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:med13_human(display_long)|uniprotkb:TRAP240(gene name synonym)|uniprotkb:MED13(gene name)|psi-mi:MED13(display_short)|uniprotkb:ARC250(gene name synonym)|uniprotkb:KIAA0593(gene name synonym)|uniprotkb:Mediator complex subunit 13(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 240 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 1(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex component DRIP250(gene name synonym)|uniprotkb:Activator-recruited cofactor 250 kDa component(gene name synonym)|uniprotkb:THRAP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481112|imex:IM-26985-337 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM refseq:NP_005112.2|ensembl:ENSG00000108510(gene)|ensembl:ENST00000397786(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|interpro:IPR009401(TRAP240)|interpro:IPR041285|mint:Q9UHV7|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31468N - - comment:"author score: 63" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:ZNWwmsetsKLA56joRzRL0UKjq9Y9606 rigid:fkTGen4snam1YYN5NZM6kE3hSL8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43513 uniprotkb:P49336 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-394377|uniprotkb:Q5VUF3|uniprotkb:Q6ISB5|ensembl:ENSP00000370938 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:cdk8_human(display_long)|uniprotkb:CDK8(gene name)|psi-mi:CDK8(display_short)|uniprotkb:Cell division protein kinase 8(gene name synonym)|uniprotkb:Mediator of RNA polymerase II transcription subunit CDK8(gene name synonym)|uniprotkb:Mediator complex subunit CDK8(gene name synonym)|uniprotkb:Protein kinase K35(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481112|imex:IM-26985-337 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM refseq:NP_001305297.1|refseq:NP_001251.1|ensembl:ENSG00000132964(gene)|ensembl:ENST00000381527(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006468"(protein phosphorylation)|rcsb pdb:5FGK|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0016592"(mediator complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P49336|rcsb pdb:3RGF|rcsb pdb:4CRL|rcsb pdb:4F6S|rcsb pdb:4F6U|rcsb pdb:4F6W|rcsb pdb:4F70|rcsb pdb:4F7J|rcsb pdb:4F7L|rcsb pdb:4F7N|rcsb pdb:4F7S|rcsb pdb:4G6L|rcsb pdb:5BNJ|rcsb pdb:5CEI|rcsb pdb:5HBE|rcsb pdb:5HBH|rcsb pdb:5HBJ|rcsb pdb:5HNB|rcsb pdb:5HVY|rcsb pdb:5I5Z|rcsb pdb:5ICP|rcsb pdb:5IDN|rcsb pdb:5IDP|rcsb pdb:5XQX|rcsb pdb:5XS2|rcsb pdb:6QTG|rcsb pdb:6QTJ|rcsb pdb:6R3S|rcsb pdb:6T41|rcsb pdb:6TPA|rcsb pdb:6Y0A|reactome:R-HSA-1989781|reactome:R-HSA-2122947|reactome:R-HSA-212436|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-381340|dip:DIP-32595N - - comment:"author score: 64" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:f+78iyCfA9osCQ82uY6reu3JKzo9606 rigid:fkTGen4snam1YYN5NZM6kE3hSL8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43513 uniprotkb:P36954 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-395202|uniprotkb:Q6NW05|uniprotkb:B2R5J2|ensembl:ENSP00000221859 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:rpb9_human(display_long)|uniprotkb:POLR2I(gene name)|psi-mi:POLR2I(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit I(gene name synonym)|uniprotkb:RNA polymerase II 14.5 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481112|imex:IM-26985-337 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM refseq:NP_006224.1|ensembl:ENSG00000105258(gene)|ensembl:ENST00000221859(transcript)|go:"GO:0001193"(maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034012|mint:P36954|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32917N - - comment:"author score: 67" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:YZUW2UDzj1RhCC46iaX1LvYayNA9606 rigid:fkTGen4snam1YYN5NZM6kE3hSL8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43513 uniprotkb:P30876 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-394712|uniprotkb:Q8IZ61|uniprotkb:A8K1A8|ensembl:ENSP00000312735|ensembl:ENSP00000370625 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:rpb2_human(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit B(gene name synonym)|uniprotkb:RNA polymerase II subunit B2(gene name synonym)|uniprotkb:RNA polymerase II subunit 2(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 140 kDa polypeptide(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481112|imex:IM-26985-337 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM refseq:NP_000929.1|refseq:NP_001290197.1|refseq:NP_001290198.1|ensembl:ENSG00000047315(gene)|ensembl:ENST00000314595(transcript)|ensembl:ENST00000381227(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|mint:P30876|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32910N - - comment:"author score: 67" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:YhEjtfLk2QnbRPefOp8ZHX0ejak9606 rigid:fkTGen4snam1YYN5NZM6kE3hSL8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43513 uniprotkb:P24928 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-295301|uniprotkb:A6NN93|uniprotkb:B9EH88|uniprotkb:Q6NX41|intact:EBI-17957133|intact:EBI-14758660|intact:EBI-13324911|intact:EBI-23311874 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:rpb1_human(display_long)|uniprotkb:POLR2A(gene name)|psi-mi:POLR2A(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit A(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:POLR2(gene name synonym)|uniprotkb:RNA-directed RNA polymerase II subunit RPB1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481112|imex:IM-26985-337 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM refseq:NP_000928.1|mint:P24928|dip:DIP-29011N|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0019900"(kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:2GHQ|rcsb pdb:2GHT|rcsb pdb:2LTO|rcsb pdb:3D9K|rcsb pdb:3D9L|rcsb pdb:3D9M|rcsb pdb:3D9N|rcsb pdb:3D9O|rcsb pdb:3D9P|rcsb pdb:4JXT|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:5M3H|rcsb pdb:5M3J|rcsb pdb:6DRD|rcsb pdb:6F5P|rcsb pdb:6G0R|rcsb pdb:6IC8|rcsb pdb:6IC9|rcsb pdb:6O9L|rcsb pdb:6Q5Y|rcsb pdb:6XKB|rcsb pdb:6XRE|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095 - - comment:"author score: 71" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:Si2fgh4AMaNtlzvSQhvsuPusX7s9606 rigid:fkTGen4snam1YYN5NZM6kE3hSL8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43513 uniprotkb:Q71F56 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-394435|uniprotkb:A1L469|uniprotkb:Q68DN4|uniprotkb:Q9H8C0|uniprotkb:Q9NSY9|uniprotkb:Q9UFD8|uniprotkb:Q9UPX5|ensembl:ENSP00000281928 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:md13l_human(display_long)|uniprotkb:Mediator complex subunit 13-like(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 2(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 240 kDa component-like(gene name synonym)|uniprotkb:MED13L(gene name)|psi-mi:MED13L(display_short)|uniprotkb:KIAA1025(gene name synonym)|uniprotkb:PROSIT240(gene name synonym)|uniprotkb:THRAP2(gene name synonym)|uniprotkb:TRAP240L(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481112|imex:IM-26985-337 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM refseq:NP_056150.1|ensembl:ENSG00000123066(gene)|ensembl:ENST00000281928(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR009401(TRAP240)|interpro:IPR021643|interpro:IPR041285|mint:Q71F56|reactome:R-HSA-1989781|reactome:R-HSA-381340 - - comment:"author score: 80" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:Zdj5dM/HEWW8zS27yaXsR+ZOxZs9606 rigid:fkTGen4snam1YYN5NZM6kE3hSL8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43513 uniprotkb:P19387 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-394729|uniprotkb:O15161|ensembl:ENSP00000219252 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:rpb3_human(display_long)|uniprotkb:POLR2C(gene name)|psi-mi:POLR2C(display_short)|uniprotkb:A-152E5.7(orf name)|uniprotkb:DNA-directed RNA polymerase II subunit C(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 33 kDa polypeptide(gene name synonym)|uniprotkb:RPB31(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481112|imex:IM-26985-337 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM refseq:NP_116558.1|ensembl:ENSG00000102978(gene)|ensembl:ENST00000219252(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001514(DNA-directed RNA polymerase, 30-40 kDa subunit, conserved site)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR036603|interpro:IPR036643|mint:P19387|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32911N - - comment:"author score: 92" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:UXFC+i+QqB2WRgL9OiYSQ66L36c9606 rigid:fkTGen4snam1YYN5NZM6kE3hSL8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43513 uniprotkb:Q15528 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-394687|uniprotkb:Q5T8U0|uniprotkb:O76072|uniprotkb:B3KW83|uniprotkb:B3KWX4|ensembl:ENSP00000342343|ensembl:ENSP00000482438|ensembl:ENSP00000485880|ensembl:ENSP00000487580 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:med22_human(display_long)|uniprotkb:Mediator complex subunit 22(gene name synonym)|uniprotkb:MED22(gene name)|psi-mi:MED22(display_short)|uniprotkb:Surfeit locus protein 5(gene name synonym)|uniprotkb:SURF5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481112|imex:IM-26985-337 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM refseq:NP_598395.1|refseq:NP_852468.1|ensembl:ENSG00000148297(gene)|ensembl:ENSG00000281022(gene)|ensembl:ENST00000343730(transcript)|ensembl:ENST00000610672(transcript)|ensembl:ENST00000629522(transcript)|ensembl:ENST00000631196(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR009332(Surfeit locus 5)|mint:Q15528|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 - - comment:"author score: 104" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:bAtK0Srk81ujvVt2Gj0+py7RCZY9606 rigid:fkTGen4snam1YYN5NZM6kE3hSL8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43513 uniprotkb:Q93074 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-394357|uniprotkb:O15410|uniprotkb:O75557|uniprotkb:Q9UHV6|uniprotkb:Q9UND7|ensembl:ENSP00000363193 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:med12_human(display_long)|uniprotkb:TRAP230(gene name synonym)|uniprotkb:MED12(gene name)|psi-mi:MED12(display_short)|uniprotkb:ARC240(gene name synonym)|uniprotkb:CAGH45(gene name synonym)|uniprotkb:HOPA(gene name synonym)|uniprotkb:KIAA0192(gene name synonym)|uniprotkb:Mediator complex subunit 12(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 230 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 240 kDa component(gene name synonym)|uniprotkb:CAG repeat protein 45(gene name synonym)|uniprotkb:OPA-containing protein(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 11 protein(gene name synonym)|uniprotkb:TNRC11(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481112|imex:IM-26985-337 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM refseq:NP_005111.2|ensembl:ENSG00000184634(gene)|ensembl:ENST00000374080(transcript)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0090245"(axis elongation involved in somitogenesis)|go:"GO:1990403"(embryonic brain development)|interpro:IPR019035|interpro:IPR021989|interpro:IPR021990|mint:Q93074|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0014044"(Schwann cell development)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021510"(spinal cord development)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048702"(embryonic neurocranium morphogenesis)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|dip:DIP-31459N - - comment:"author score: 109" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:soNqTi3/n+qnj+P4AX/cPJzTK2U9606 rigid:fkTGen4snam1YYN5NZM6kE3hSL8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43513 uniprotkb:Q9BUE0 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-394640|uniprotkb:Q9NXU9|uniprotkb:D3DPM1|ensembl:ENSP00000362948|ensembl:ENSP00000381963|ensembl:ENSP00000494048|ensembl:ENSP00000494184 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:med18_human(display_long)|uniprotkb:MED18(gene name)|psi-mi:MED18(display_short)|uniprotkb:Mediator complex subunit 18(gene name synonym)|uniprotkb:p28b(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481112|imex:IM-26985-337 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM refseq:NP_001120822.1|refseq:NP_060108.2|refseq:XP_005245971.1|ensembl:ENSG00000130772(gene)|ensembl:ENSG00000284944(gene)|ensembl:ENST00000373842(transcript)|ensembl:ENST00000398997(transcript)|ensembl:ENST00000645794(transcript)|ensembl:ENST00000647352(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006369"(termination of RNA polymerase II transcription)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR019095|mint:Q9BUE0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 - - comment:"author score: 123" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:Or+Q+iu65H7u4G0WU7AsIL0DM0c9606 rigid:fkTGen4snam1YYN5NZM6kE3hSL8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43513 uniprotkb:O95402 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-394392|uniprotkb:A1A4S3|uniprotkb:Q0VGB6|intact:EBI-28974475|ensembl:ENSP00000263390 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:med26_human(display_long)|uniprotkb:ARC70(gene name synonym)|uniprotkb:MED26(gene name)|psi-mi:MED26(display_short)|uniprotkb:Mediator complex subunit 26(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 7(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP70(gene name synonym)|uniprotkb:Activator-recruited cofactor 70 kDa component(gene name synonym)|uniprotkb:CRSP7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481112|imex:IM-26985-337 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM ensembl:ENSP00000263390|ensembl:ENST00000611692|ensembl:ENSP00000484490|refseq:NP_004822.2|ensembl:ENSG00000105085(gene)|ensembl:ENST00000263390(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR017923|interpro:IPR031416|interpro:IPR031417|interpro:IPR035441|interpro:IPR042376|mint:O95402|rcsb pdb:5ODD|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31464N - - comment:"author score: 134" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:1kRmQ+QH5uQkKVfjo2Rc2SkAyKc9606 rigid:fkTGen4snam1YYN5NZM6kE3hSL8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43513 uniprotkb:Q9P086 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-394704|uniprotkb:Q6NS89|ensembl:ENSP00000293777 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:med11_human(display_long)|uniprotkb:Mediator complex subunit 11(gene name synonym)|uniprotkb:MED11(gene name)|psi-mi:MED11(display_short)|uniprotkb:HSPC296(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481112|imex:IM-26985-337 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM refseq:NP_001291929.1|refseq:NP_001001683.1|ensembl:ENSG00000161920(gene)|ensembl:ENST00000293777(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019404|mint:Q9P086|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|go:"GO:0003712"(transcription coregulator activity) - - comment:"author score: 146" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:y7SZi5hIo5aOatJSZi98Hqt082A9606 rigid:fkTGen4snam1YYN5NZM6kE3hSL8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43513 uniprotkb:Q96G25 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-394405|uniprotkb:A9IZ91|uniprotkb:Q96FQ4|uniprotkb:A9IZ92|uniprotkb:Q5JUY8|ensembl:ENSP00000361535 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:med8_human(display_long)|uniprotkb:MED8(gene name)|psi-mi:MED8(display_short)|uniprotkb:Mediator complex subunit 8(gene name synonym)|uniprotkb:Activator-recruited cofactor 32 kDa component(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481112|imex:IM-26985-337 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM refseq:NP_443109.2|refseq:NP_963836.2|refseq:NP_001001653.1|ensembl:ENSG00000159479(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|mint:Q96G25|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENST00000372457(transcript) - - comment:"author score: 150" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:e/ye7rfa2E1XOPb5vVhI9Nvqmxw9606 rigid:fkTGen4snam1YYN5NZM6kE3hSL8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43513 uniprotkb:Q9H204 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-514199|uniprotkb:Q9BZJ5|ensembl:ENSP00000237380 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:med28_human(display_long)|uniprotkb:Mediator complex subunit 28(gene name synonym)|uniprotkb:Tumor angiogenesis marker EG-1(gene name synonym)|uniprotkb:Endothelial-derived protein 1(gene name synonym)|uniprotkb:Merlin and Grb2-interacting cytoskeletal protein(gene name synonym)|uniprotkb:MED28(gene name)|psi-mi:MED28(display_short)|uniprotkb:EG1(gene name synonym)|uniprotkb:FKSG20(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481112|imex:IM-26985-337 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM refseq:NP_079481.2|ensembl:ENSG00000118579(gene)|ensembl:ENST00000237380(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0051151"(negative regulation of smooth muscle cell differentiation)|interpro:IPR021640|mint:Q9H204|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 - - comment:"author score: 156" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:1gt/0vP7vWJ+M1fU+qZPcWGj34U9606 rigid:fkTGen4snam1YYN5NZM6kE3hSL8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43513 uniprotkb:O75586 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-394624|uniprotkb:Q6FHQ4|uniprotkb:Q9BTH1|uniprotkb:Q9UHL1|uniprotkb:O15401|uniprotkb:Q53FE3|uniprotkb:Q53HJ3|uniprotkb:B4DU17|uniprotkb:B4E2P0|ensembl:ENSP00000256379 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:med6_human(display_long)|uniprotkb:ARC33(gene name synonym)|uniprotkb:MED6(gene name)|psi-mi:MED6(display_short)|uniprotkb:Mediator complex subunit 6(gene name synonym)|uniprotkb:Activator-recruited cofactor 33 kDa component(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-28(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481112|imex:IM-26985-337 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM refseq:NP_005457.2|refseq:NP_001271138.1|refseq:NP_001271139.1|refseq:NP_001271140.1|ensembl:ENSG00000133997(gene)|ensembl:ENST00000256379(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR007018(MED6 mediator)|interpro:IPR016820(Mediator complex, subunit 6, metazoa/plant)|interpro:IPR038566|mint:O75586|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31456N - - comment:"author score: 158" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:QYK+2tX/HC1OGGPu3b3S1v/ODR89606 rigid:fkTGen4snam1YYN5NZM6kE3hSL8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43513 uniprotkb:Q9H944 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-394644|uniprotkb:Q9Y429|uniprotkb:O95821|uniprotkb:Q5T8J4|uniprotkb:B4DE08|ensembl:ENSP00000265350 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:med20_human(display_long)|uniprotkb:TRFP(gene name synonym)|uniprotkb:MED20(gene name)|psi-mi:MED20(display_short)|uniprotkb:Mediator complex subunit 20(gene name synonym)|uniprotkb:TRF-proximal protein homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481112|imex:IM-26985-337 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM refseq:NP_004266.2|refseq:NP_001292384.1|refseq:NP_001292385.1|refseq:NP_001292386.1|go:"GO:0016592"(mediator complex)|interpro:IPR013921(TATA-binding related factor)|mint:Q9H944|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000124641(gene)|ensembl:ENST00000265350(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|dip:DIP-31449N - - comment:"author score: 158" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:MpYOrONH6+0lKIlO6J+Szjzkw2A9606 rigid:fkTGen4snam1YYN5NZM6kE3hSL8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43513 uniprotkb:Q9NVC6 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-394562|uniprotkb:Q9HA81|uniprotkb:Q9UNP7|uniprotkb:Q9Y2W0|uniprotkb:Q9Y660|uniprotkb:B3KN07|ensembl:ENSP00000251871 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:med17_human(display_long)|uniprotkb:TRAP80(gene name synonym)|uniprotkb:MED17(gene name)|psi-mi:MED17(display_short)|uniprotkb:ARC77(gene name synonym)|uniprotkb:DRIP80(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 6(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP77(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 80 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 80 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 77 kDa component(gene name synonym)|uniprotkb:CRSP6(gene name synonym)|uniprotkb:DRIP77(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481112|imex:IM-26985-337 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM refseq:NP_004259.3|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|ensembl:ENSG00000042429(gene)|ensembl:ENST00000251871(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019313|mint:Q9NVC6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31451N - - comment:"author score: 158" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:P2hRQOjWEtjw5V+lt7J9TP3VbpU9606 rigid:fkTGen4snam1YYN5NZM6kE3hSL8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43513 uniprotkb:Q96HR3 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-394659|uniprotkb:C6GKU9|intact:EBI-11137618|ensembl:ENSP00000297347 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:med30_human(display_long)|uniprotkb:TRAP25(gene name synonym)|uniprotkb:MED30(gene name)|psi-mi:MED30(display_short)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)|uniprotkb:TRAP/Mediator complex component TRAP25(gene name synonym)|uniprotkb:THRAP6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481112|imex:IM-26985-337 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM refseq:NP_542382.1|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|mint:Q96HR3|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001269915.1|ensembl:ENSG00000164758(gene)|ensembl:ENST00000297347(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity) - - comment:"author score: 159" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:dUgR7zxbKAcYqPKb8teHBLgUhWY9606 rigid:fkTGen4snam1YYN5NZM6kE3hSL8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43513 uniprotkb:Q6P2C8 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-394603|uniprotkb:Q4F964|uniprotkb:O95401|uniprotkb:Q5VTA4|uniprotkb:Q5VTA5|uniprotkb:Q9BU57|uniprotkb:Q9NYR4|uniprotkb:V9GYV9|ensembl:ENSP00000292035 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:med27_human(display_long)|uniprotkb:MED27(gene name)|psi-mi:MED27(display_short)|uniprotkb:Mediator complex subunit 27(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 8(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP34(gene name synonym)|uniprotkb:P37 TRAP/SMCC/PC2 subunit(gene name synonym)|uniprotkb:CRSP34(gene name synonym)|uniprotkb:CRSP8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481112|imex:IM-26985-337 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM refseq:NP_001240811.1|refseq:NP_004260.2|refseq:NP_001240810.1|dip:DIP-31465N|ensembl:ENSG00000160563(gene)|ensembl:ENST00000292035(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021627|mint:Q6P2C8|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 - - comment:"author score: 166" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:V1clNhbtflCzCkC7OnaHGYrmQp89606 rigid:fkTGen4snam1YYN5NZM6kE3hSL8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43513 uniprotkb:Q9BTT4 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-394354|uniprotkb:C6G491|ensembl:ENSP00000255764 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:med10_human(display_long)|uniprotkb:MED10(gene name)|psi-mi:MED10(display_short)|uniprotkb:L6(orf name)|uniprotkb:TRG17(orf name)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Transformation-related gene 17 protein(gene name synonym)|uniprotkb:Transformation-related gene 20 protein(gene name synonym)|uniprotkb:TRG20(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481112|imex:IM-26985-337 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM ensembl:ENSG00000133398(gene)|ensembl:ENST00000255764(transcript)|refseq:NP_115662.2|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019145|mint:Q9BTT4|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|go:"GO:0000151"(ubiquitin ligase complex)|dip:DIP-31457N - - comment:"author score: 187" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:LzJW7C8kl2pWmffOjo8S/FNSS9I9606 rigid:fkTGen4snam1YYN5NZM6kE3hSL8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43513 uniprotkb:Q15648 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-394459|uniprotkb:A2RRQ6|uniprotkb:O43810|uniprotkb:O75447|uniprotkb:Q6P9H7|uniprotkb:Q6PK58|uniprotkb:Q9HD39|ensembl:ENSP00000300651 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:med1_human(display_long)|uniprotkb:TRIP2(gene name synonym)|uniprotkb:MED1(gene name)|psi-mi:MED1(display_short)|uniprotkb:ARC205(gene name synonym)|uniprotkb:DRIP205(gene name synonym)|uniprotkb:TRAP220(gene name synonym)|uniprotkb:Activator-recruited cofactor 205 kDa component(gene name synonym)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-binding protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 220 kDa component(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 2(gene name synonym)|uniprotkb:p53 regulatory protein RB18A(gene name synonym)|uniprotkb:Vitamin D receptor-interacting protein complex component DRIP205(gene name synonym)|uniprotkb:CRSP1(gene name synonym)|uniprotkb:CRSP200(gene name synonym)|uniprotkb:DRIP230(gene name synonym)|uniprotkb:PBP(gene name synonym)|uniprotkb:PPARBP(gene name synonym)|uniprotkb:PPARGBP(gene name synonym)|uniprotkb:RB18A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481112|imex:IM-26985-337 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM refseq:NP_004765.2|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR019680|mint:Q15648|rcsb pdb:1RJK|rcsb pdb:1RK3|rcsb pdb:1RKG|rcsb pdb:1RKH|rcsb pdb:2O4J|rcsb pdb:2O4R|rcsb pdb:2ZFX|rcsb pdb:3A2H|rcsb pdb:3AUN|rcsb pdb:3VJS|rcsb pdb:3VJT|rcsb pdb:3VRT|rcsb pdb:3VRU|rcsb pdb:3VRV|rcsb pdb:3VRW|rcsb pdb:3W0G|rcsb pdb:3W0H|rcsb pdb:3W0I|rcsb pdb:3W0J|rcsb pdb:3W5P|rcsb pdb:3W5Q|rcsb pdb:3W5R|rcsb pdb:3W5T|rcsb pdb:3WT5|rcsb pdb:3WT6|rcsb pdb:3WT7|rcsb pdb:3WTQ|rcsb pdb:4YNK|rcsb pdb:5AWJ|rcsb pdb:5AWK|rcsb pdb:5B41|rcsb pdb:5B5B|rcsb pdb:5GIC|rcsb pdb:5GID|rcsb pdb:5GIE|rcsb pdb:5XPM|rcsb pdb:5XPN|rcsb pdb:5XPO|rcsb pdb:5XPP|rcsb pdb:5XUQ|rcsb pdb:5XZF|rcsb pdb:5XZH|rcsb pdb:5ZWE|rcsb pdb:5ZWF|rcsb pdb:5ZWH|rcsb pdb:5ZWI|rcsb pdb:6D94|rcsb pdb:6JEZ|rcsb pdb:6K5O|rcsb pdb:6ONJ|rcsb pdb:7C7V|rcsb pdb:7C7W|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9707564|reactome:R-HSA-9707616|ensembl:ENSG00000125686(gene)|ensembl:ENST00000300651(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003406"(retinal pigment epithelium development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0050693"(LBD domain binding)|dip:DIP-24212N - - comment:"author score: 190" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:A4EIAri9zYycSlTA7s6NzbOi9n49606 rigid:fkTGen4snam1YYN5NZM6kE3hSL8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43513 uniprotkb:O60244 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-394489|uniprotkb:Q4KMR7|uniprotkb:Q9UNB3|ensembl:ENSP00000323720 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:med14_human(display_long)|uniprotkb:TRAP170(gene name synonym)|uniprotkb:MED14(gene name)|psi-mi:MED14(display_short)|uniprotkb:ARC150(gene name synonym)|uniprotkb:DRIP150(gene name synonym)|uniprotkb:EXLM1(gene name synonym)|uniprotkb:RGR1(gene name synonym)|uniprotkb:Mediator complex subunit 14(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 2(gene name synonym)|uniprotkb:RGR1 homolog(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP150(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 150 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 170 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 150 kDa component(gene name synonym)|uniprotkb:CRSP2(gene name synonym)|uniprotkb:CXorf4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481112|imex:IM-26985-337 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM refseq:NP_004220.2|ensembl:ENSG00000180182(gene)|ensembl:ENST00000324817(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR013947(Mediator complex, subunit MED14)|mint:O60244|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31460N - - comment:"author score: 194" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:73RBAnwmB4Lyl/kcsg7NKSUmA4c9606 rigid:fkTGen4snam1YYN5NZM6kE3hSL8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43513 uniprotkb:A0JLT2 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-394430|uniprotkb:Q8IV02|intact:EBI-394763|uniprotkb:Q8IZD1 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:med19_human(display_long)|uniprotkb:MED19(gene name)|psi-mi:MED19(display_short)|uniprotkb:LCMR1(gene name synonym)|uniprotkb:Lung cancer metastasis-related protein 1(gene name synonym)|uniprotkb:Mediator complex subunit 19(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481112|imex:IM-26985-337 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM refseq:NP_001304007.1|refseq:NP_703151.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR019403|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|mint:A0JLT2|dip:DIP-31467N - - comment:"author score: 195" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:zcHhU2hQvuTpkFZz/xEKYmjrwOA9606 rigid:fkTGen4snam1YYN5NZM6kE3hSL8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43513 uniprotkb:Q13503 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481112|imex:IM-26985-337 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N - - comment:"author score: 204" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606 rigid:fkTGen4snam1YYN5NZM6kE3hSL8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43513 uniprotkb:Q9NPJ6 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481112|imex:IM-26985-337 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 - - comment:"author score: 208" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:Bept2Oec50gruA9e4pf+eEUiANM9606 rigid:fkTGen4snam1YYN5NZM6kE3hSL8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43513 uniprotkb:Q9NWA0 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-394653|ensembl:ENSP00000268711 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:med9_human(display_long)|uniprotkb:MED9(gene name)|psi-mi:MED9(display_short)|uniprotkb:Mediator complex subunit 9(gene name synonym)|uniprotkb:MED25(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481112|imex:IM-26985-337 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM refseq:NP_060489.1|ensembl:ENSG00000141026(gene)|ensembl:ENST00000268711(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR011425(RNA polymerase II transcription mediator)|interpro:IPR037212|interpro:IPR039242|mint:Q9NWA0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 - - comment:"author score: 219" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:VSYpA1Aqh2FEaZIEF/6iCIpoPEc9606 rigid:fkTGen4snam1YYN5NZM6kE3hSL8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43513 uniprotkb:Q9Y3C7 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 intact:EBI-394707|uniprotkb:B2R4L9|ensembl:ENSP00000225728 psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:med31_human(display_long)|uniprotkb:CGI-125(orf name)|uniprotkb:SOH1(gene name synonym)|uniprotkb:MED31(gene name)|psi-mi:MED31(display_short)|uniprotkb:Mediator complex subunit 31(gene name synonym)|uniprotkb:Mediator complex subunit SOH1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481112|imex:IM-26985-337 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM refseq:NP_057144.1|ensembl:ENSG00000108590(gene)|ensembl:ENST00000225728(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0060173"(limb development)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR008831(SOH1)|interpro:IPR038089|mint:Q9Y3C7|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 - - comment:"author score: 222" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rogid:QRmf6b+uoUOubBcvJbBfl9NgRTQ9606 rigid:fkTGen4snam1YYN5NZM6kE3hSL8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92734 uniprotkb:O95243 intact:EBI-357061|uniprotkb:Q15656|intact:EBI-357314|uniprotkb:Q969I2|uniprotkb:D3DN49|uniprotkb:K0J5S8|uniprotkb:K0J6K2|intact:EBI-28969365|ensembl:ENSP00000240851|ensembl:ENSP00000419960|ensembl:ENSP00000420797|ensembl:ENSP00000501815|ensembl:ENSP00000502071|ensembl:ENSP00000502450|ensembl:ENSP00000502592|ensembl:ENSP00000502734|uniprotkb:G5E9V1 intact:EBI-348011|ensembl:ENSP00000249910|uniprotkb:Q7Z4T3|uniprotkb:Q96F09|uniprotkb:D3DNC3|uniprotkb:D3DNC4|uniprotkb:Q2MD36|uniprotkb:B4DZN2|uniprotkb:E9PEE4|intact:EBI-11018783 psi-mi:tfg_human(display_long)|uniprotkb:TFG(gene name)|psi-mi:TFG(display_short)|uniprotkb:TRK-fused gene protein(gene name synonym) psi-mi:mbd4_human(display_long)|uniprotkb:MBD4(gene name)|psi-mi:MBD4(display_short)|uniprotkb:MED1(gene name synonym)|uniprotkb:Methyl-CpG-binding protein MBD4(gene name synonym)|uniprotkb:Methyl-CpG-binding endonuclease 1(gene name synonym)|uniprotkb:Mismatch-specific DNA N-glycosylase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25480623|imex:IM-26985-179 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001007566.1|refseq:NP_001182407.1|refseq:NP_001182408.1|refseq:NP_006061.2|ensembl:ENSP00000240851|ensembl:ENST00000463568|ensembl:ENSP00000419504|ensembl:ENST00000476228|ensembl:ENSP00000417952|ensembl:ENSP00000420797|ensembl:ENSP00000419960|ensembl:ENST00000615993|ensembl:ENSP00000479269|ensembl:ENST00000620299|ensembl:ENSP00000479981|ensembl:ENSP00000502734|ensembl:ENST00000674645|ensembl:ENSP00000501892|ensembl:ENST00000674758|ensembl:ENSP00000502502|ensembl:ENST00000675047|ensembl:ENSP00000502497|ensembl:ENSP00000502592|ensembl:ENST00000675420|ensembl:ENSP00000502516|ensembl:ENSP00000502450|ensembl:ENST00000675543|ensembl:ENSP00000501815|ensembl:ENST00000675586|ensembl:ENSP00000502329|ensembl:ENST00000676111|ensembl:ENSP00000502139|ensembl:ENST00000676308|ensembl:ENSP00000502697|ensembl:ENSP00000502071|ensembl:ENST00000676431|ensembl:ENSP00000502698|ensembl:ENSP00000502229|refseq:XP_006713535.1|refseq:XP_006713536.1|ensembl:ENSG00000114354(gene)|ensembl:ENST00000240851(transcript)|ensembl:ENST00000487505(transcript)|ensembl:ENST00000490574(transcript)|ensembl:ENST00000674615(transcript)|ensembl:ENST00000675243(transcript)|ensembl:ENST00000675499(transcript)|ensembl:ENST00000675553(transcript)|ensembl:ENST00000676395(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0070971"(endoplasmic reticulum exit site)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR033512|interpro:IPR034857|mint:Q92734|reactome:R-HSA-204005|refseq:XP_011510636.1|refseq:XP_005247123.1|refseq:XP_016861016.1|refseq:XP_016861017.1|refseq:XP_016861018.1|refseq:XP_016861019.1 ensembl:ENSG00000129071(gene)|ensembl:ENST00000249910(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003696"(satellite DNA binding)|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0008263"(pyrimidine-specific mismatch base pair DNA N-glycosylase activity)|go:"GO:0019104"(DNA N-glycosylase activity)|go:"GO:0032355"(response to estradiol)|go:"GO:0045008"(depyrimidination)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR011257(DNA glycosylase)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR017352(Methyl-CpG binding protein MBD4)|mint:O95243|rcsb pdb:2MOE|rcsb pdb:3IHO|rcsb pdb:4DK9|rcsb pdb:4E9E|rcsb pdb:4E9F|rcsb pdb:4E9G|go:"GO:0016607"(nuclear speck)|rcsb pdb:4E9H|rcsb pdb:4EA4|rcsb pdb:4EA5|rcsb pdb:4LG7|rcsb pdb:4OFA|rcsb pdb:4OFE|rcsb pdb:4OFH|rcsb pdb:5CHZ|rcsb pdb:6VJW|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110357|refseq:NP_003916.1|refseq:NP_001263199.1|refseq:NP_001263201.1|refseq:NP_001263202.1|refseq:NP_001263200.1 - comment:"author score: 12" - figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y7aghh0X3Ewgpzcx5h5nB+X2dII9606 rogid:KnHKS0T8xT8in2vbu2jrHchcd5U9606 rigid:2ur5cQhgjcgebLzkF/eOk3qI5aA false - tandem tag:n-n - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P55197 uniprotkb:Q8TEK3 intact:EBI-1104952|ensembl:ENSP00000307411|ensembl:ENSP00000366258|ensembl:ENSP00000488569|uniprotkb:Q5JT37|uniprotkb:Q66K63|uniprotkb:B1ANA8|uniprotkb:Q5VX90|intact:EBI-11060398 intact:EBI-2619253|uniprotkb:O60379|uniprotkb:Q96JL1|ensembl:ENSP00000381657 psi-mi:af10_human(display_long)|uniprotkb:MLLT10(gene name)|psi-mi:MLLT10(display_short)|uniprotkb:AF10(gene name synonym)|uniprotkb:ALL1-fused gene from chromosome 10 protein(gene name synonym) psi-mi:dot1l_human(display_long)|uniprotkb:DOT1L(gene name)|psi-mi:DOT1L(display_short)|uniprotkb:KIAA1814(gene name synonym)|uniprotkb:KMT4(gene name synonym)|uniprotkb:Histone H3-K79 methyltransferase(gene name synonym)|uniprotkb:DOT1-like protein(gene name synonym)|uniprotkb:Lysine N-methyltransferase 4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481286|imex:IM-26985-109 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000078403(gene)|ensembl:ENSP00000307411|ensembl:ENSP00000366258|ensembl:ENST00000377072|ensembl:ENSP00000366272|ensembl:ENST00000377091|ensembl:ENSP00000366295|ensembl:ENST00000377100|ensembl:ENSP00000366304|ensembl:ENST00000621220|ensembl:ENSP00000484335|ensembl:ENSP00000488569|ensembl:ENST00000652497|ensembl:ENSP00000498595|refseq:NP_001182556.1|refseq:NP_004632.1|ensembl:ENST00000307729(transcript)|ensembl:ENST00000377059(transcript)|ensembl:ENST00000631589(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|mint:P55197|rcsb pdb:5DAG|rcsb pdb:5DAH|rcsb pdb:6CKN|rcsb pdb:6CKO|rcsb pdb:6JN2|refseq:NP_001182557.1|refseq:NP_001182559.1|refseq:NP_001182555.1|refseq:NP_001311225.1|dip:DIP-37633N refseq:NP_115871.1|interpro:IPR030445|mint:Q8TEK3|rcsb pdb:1NW3|rcsb pdb:2MV7|rcsb pdb:3QOW|rcsb pdb:3QOX|rcsb pdb:3SR4|rcsb pdb:3SX0|rcsb pdb:3UWP|rcsb pdb:4EK9|rcsb pdb:4EKG|rcsb pdb:4EKI|rcsb pdb:4EQZ|rcsb pdb:4ER0|rcsb pdb:4ER3|rcsb pdb:4ER5|rcsb pdb:4ER6|rcsb pdb:4ER7|rcsb pdb:4HRA|rcsb pdb:4WVL|rcsb pdb:5DRT|rcsb pdb:5DRY|rcsb pdb:5DSX|rcsb pdb:5DT2|rcsb pdb:5DTM|rcsb pdb:5DTQ|rcsb pdb:5DTR|rcsb pdb:5JUW|rcsb pdb:5MVS|rcsb pdb:5MW3|rcsb pdb:5MW4|rcsb pdb:6IN3|rcsb pdb:6J99|rcsb pdb:6JM9|rcsb pdb:6JMA|rcsb pdb:6JN2|rcsb pdb:6NJ9|rcsb pdb:6NN6|rcsb pdb:6NQA|rcsb pdb:6O96|rcsb pdb:6TE6|rcsb pdb:6TEL|rcsb pdb:6TEN|rcsb pdb:7BWD|rcsb pdb:7EDP|reactome:R-HSA-3214841|rcsb pdb:6NOG|ensembl:ENSG00000104885(gene)|ensembl:ENST00000398665(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006348"|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010467"(gene expression)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0003677"(DNA binding)|go:"GO:0031151"("histone methyltransferase activity (H3-K79 specific)")|go:"GO:0032200"(telomere organization)|go:"GO:0005634"(nucleus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034729"(histone H3-K79 methylation)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046425"(regulation of receptor signaling pathway via JAK-STAT)|go:"GO:2000677"(regulation of transcription regulatory region DNA binding)|interpro:IPR021169|interpro:IPR025789|interpro:IPR029063|dip:DIP-56410N - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:7jWr9+kJgTFVbZvq+BndUhHQstA9606 rogid:AaD+YTOZFAyvyecKC/4b6An2pFA9606 rigid:RC7zWVpsTDdYa69qvmjwzMkooNA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P55197 uniprotkb:P00441 intact:EBI-1104952|ensembl:ENSP00000307411|ensembl:ENSP00000366258|ensembl:ENSP00000488569|uniprotkb:Q5JT37|uniprotkb:Q66K63|uniprotkb:B1ANA8|uniprotkb:Q5VX90|intact:EBI-11060398 intact:EBI-990792|uniprotkb:A6NHJ0|uniprotkb:Q16669|uniprotkb:Q16711|uniprotkb:Q16838|uniprotkb:Q16839|uniprotkb:Q16840|uniprotkb:Q6NR85|ensembl:ENSP00000270142|uniprotkb:D3DSE4 psi-mi:af10_human(display_long)|uniprotkb:MLLT10(gene name)|psi-mi:MLLT10(display_short)|uniprotkb:AF10(gene name synonym)|uniprotkb:ALL1-fused gene from chromosome 10 protein(gene name synonym) psi-mi:sodc_human(display_long)|uniprotkb:Superoxide dismutase 1(gene name synonym)|uniprotkb:SOD1(gene name)|psi-mi:SOD1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481286|imex:IM-26985-109 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000078403(gene)|ensembl:ENSP00000307411|ensembl:ENSP00000366258|ensembl:ENST00000377072|ensembl:ENSP00000366272|ensembl:ENST00000377091|ensembl:ENSP00000366295|ensembl:ENST00000377100|ensembl:ENSP00000366304|ensembl:ENST00000621220|ensembl:ENSP00000484335|ensembl:ENSP00000488569|ensembl:ENST00000652497|ensembl:ENSP00000498595|refseq:NP_001182556.1|refseq:NP_004632.1|ensembl:ENST00000307729(transcript)|ensembl:ENST00000377059(transcript)|ensembl:ENST00000631589(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|mint:P55197|rcsb pdb:5DAG|rcsb pdb:5DAH|rcsb pdb:6CKN|rcsb pdb:6CKO|rcsb pdb:6JN2|refseq:NP_001182557.1|refseq:NP_001182559.1|refseq:NP_001182555.1|refseq:NP_001311225.1|dip:DIP-37633N ensembl:ENSG00000142168(gene)|ensembl:ENST00000270142(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000303"(response to superoxide)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001890"(placenta development)|go:"GO:0001895"(retina homeostasis)|go:"GO:0002262"(myeloid cell homeostasis)|go:"GO:0004784"(superoxide dismutase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005764"(lysosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007566"(embryo implantation)|go:"GO:0007569"(cell aging)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0001975"(response to amphetamine)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033081"(regulation of T cell differentiation in thymus)|go:"GO:0034465"(response to carbon monoxide)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009408"(response to heat)|go:"GO:0010033"(response to organic substance)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0031045"(dense core granule)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031667"(response to nutrient levels)|interpro:IPR024134|interpro:IPR036423|mint:P00441|rcsb pdb:1AZV|rcsb pdb:1BA9|rcsb pdb:1DSW|rcsb pdb:1FUN|rcsb pdb:1HL4|rcsb pdb:1HL5|rcsb pdb:1KMG|rcsb pdb:1L3N|rcsb pdb:1MFM|rcsb pdb:1N18|rcsb pdb:1N19|interpro:IPR018152|rcsb pdb:1OEZ|rcsb pdb:1OZT|rcsb pdb:1OZU|rcsb pdb:1P1V|rcsb pdb:1PTZ|rcsb pdb:1PU0|rcsb pdb:1RK7|rcsb pdb:1SOS|rcsb pdb:1SPD|rcsb pdb:1UXL|rcsb pdb:1UXM|rcsb pdb:2AF2|rcsb pdb:2C9S|rcsb pdb:2C9U|rcsb pdb:2C9V|rcsb pdb:2GBT|rcsb pdb:2GBU|rcsb pdb:2GBV|rcsb pdb:2LU5|rcsb pdb:2MP3|rcsb pdb:2NAM|rcsb pdb:2NNX|rcsb pdb:2R27|rcsb pdb:2V0A|rcsb pdb:2VR6|rcsb pdb:2VR7|rcsb pdb:2VR8|rcsb pdb:2WKO|rcsb pdb:2WYT|rcsb pdb:2WYZ|rcsb pdb:2WZ0|rcsb pdb:2WZ5|rcsb pdb:2WZ6|rcsb pdb:2XJK|rcsb pdb:2XJL|rcsb pdb:2ZKW|rcsb pdb:2ZKX|rcsb pdb:2ZKY|rcsb pdb:3CQP|rcsb pdb:3CQQ|rcsb pdb:3ECU|rcsb pdb:3ECV|rcsb pdb:3ECW|rcsb pdb:3GQF|rcsb pdb:3GTV|rcsb pdb:3GZO|rcsb pdb:3GZP|rcsb pdb:3GZQ|rcsb pdb:3H2P|rcsb pdb:3H2Q|rcsb pdb:3HFF|rcsb pdb:3K91|rcsb pdb:3KH3|rcsb pdb:3KH4|rcsb pdb:3LTV|rcsb pdb:3QQD|rcsb pdb:3RE0|rcsb pdb:3T5W|rcsb pdb:4A7G|rcsb pdb:4A7Q|rcsb pdb:4A7S|rcsb pdb:4A7T|rcsb pdb:4A7U|rcsb pdb:4A7V|rcsb pdb:4B3E|rcsb pdb:4BCY|rcsb pdb:4BCZ|rcsb pdb:4BD4|rcsb pdb:4FF9|rcsb pdb:4MCM|rcsb pdb:4MCN|rcsb pdb:4NIN|rcsb pdb:4NIO|rcsb pdb:4NIP|rcsb pdb:4OH2|rcsb pdb:4SOD|rcsb pdb:4XCR|rcsb pdb:5DLI|rcsb pdb:5IIW|rcsb pdb:5J07|rcsb pdb:5J0C|rcsb pdb:5J0F|rcsb pdb:5J0G|rcsb pdb:5K02|rcsb pdb:5O3Y|rcsb pdb:5O40|rcsb pdb:5U9M|rcsb pdb:5WOR|rcsb pdb:5YTO|rcsb pdb:5YTU|rcsb pdb:5YUL|rcsb pdb:6A9O|rcsb pdb:6B79|rcsb pdb:6DTK|rcsb pdb:6FFK|rcsb pdb:6FLH|rcsb pdb:6FOI|rcsb pdb:6FOL|rcsb pdb:6FON|rcsb pdb:6FP6|rcsb pdb:6SPA|rcsb pdb:6SPH|rcsb pdb:6SPI|rcsb pdb:6SPJ|rcsb pdb:6SPK|rcsb pdb:6Z3V|rcsb pdb:6Z4G|rcsb pdb:6Z4H|rcsb pdb:6Z4I|rcsb pdb:6Z4J|rcsb pdb:6Z4K|rcsb pdb:6Z4L|rcsb pdb:6Z4M|rcsb pdb:6Z4O|reactome:R-HSA-114608|reactome:R-HSA-3299685|reactome:R-HSA-8950505|rcsb pdb:5WMJ|go:"GO:0046688"(response to copper ion)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048538"(thymus development)|go:"GO:0048678"(response to axon injury)|go:"GO:0050665"(hydrogen peroxide biosynthetic process)|go:"GO:0046677"(response to antibiotic)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051087"(chaperone binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060047"(heart contraction)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0060087"(relaxation of vascular associated smooth muscle)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097332"(response to antipsychotic drug)|go:"GO:1902177"(positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001424(Superoxide dismutase, copper/zinc binding)|refseq:NP_000445.1|dip:DIP-44941N - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:7jWr9+kJgTFVbZvq+BndUhHQstA9606 rogid:W5O3CdnrxKm1kudXW04wxnCxTY09606 rigid:RC7zWVpsTDdYa69qvmjwzMkooNA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P55197 uniprotkb:P07737 intact:EBI-1104952|ensembl:ENSP00000307411|ensembl:ENSP00000366258|ensembl:ENSP00000488569|uniprotkb:Q5JT37|uniprotkb:Q66K63|uniprotkb:B1ANA8|uniprotkb:Q5VX90|intact:EBI-11060398 intact:EBI-713780|ensembl:ENSP00000225655|uniprotkb:Q53Y44 psi-mi:af10_human(display_long)|uniprotkb:MLLT10(gene name)|psi-mi:MLLT10(display_short)|uniprotkb:AF10(gene name synonym)|uniprotkb:ALL1-fused gene from chromosome 10 protein(gene name synonym) psi-mi:prof1_human(display_long)|uniprotkb:Profilin I(gene name synonym)|uniprotkb:PFN1(gene name)|psi-mi:PFN1(display_short)|uniprotkb:Epididymis tissue protein Li 184a(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481286|imex:IM-26985-109 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000078403(gene)|ensembl:ENSP00000307411|ensembl:ENSP00000366258|ensembl:ENST00000377072|ensembl:ENSP00000366272|ensembl:ENST00000377091|ensembl:ENSP00000366295|ensembl:ENST00000377100|ensembl:ENSP00000366304|ensembl:ENST00000621220|ensembl:ENSP00000484335|ensembl:ENSP00000488569|ensembl:ENST00000652497|ensembl:ENSP00000498595|refseq:NP_001182556.1|refseq:NP_004632.1|ensembl:ENST00000307729(transcript)|ensembl:ENST00000377059(transcript)|ensembl:ENST00000631589(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|mint:P55197|rcsb pdb:5DAG|rcsb pdb:5DAH|rcsb pdb:6CKN|rcsb pdb:6CKO|rcsb pdb:6JN2|refseq:NP_001182557.1|refseq:NP_001182559.1|refseq:NP_001182555.1|refseq:NP_001311225.1|dip:DIP-37633N ensembl:ENSG00000108518(gene)|ensembl:ENST00000225655(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0060074"(synapse maturation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0072562"(blood microparticle)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900029"(positive regulation of ruffle assembly)|interpro:IPR005454(Profilin, Mammalian)|interpro:IPR005455(Profilin, plant)|interpro:IPR027310|interpro:IPR029892|interpro:IPR036140|mint:P07737|rcsb pdb:1AWI|rcsb pdb:1CF0|rcsb pdb:1CJF|rcsb pdb:1FIK|rcsb pdb:1FIL|rcsb pdb:1PFL|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:3CHW|rcsb pdb:4X1L|rcsb pdb:4X1M|rcsb pdb:4X25|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6NBW|reactome:R-HSA-114608|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|reactome:R-HSA-4086400|reactome:R-HSA-5663220|reactome:R-HSA-376176|refseq:NP_005013.1|dip:DIP-30N - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:7jWr9+kJgTFVbZvq+BndUhHQstA9606 rogid:CncaC5RMylvzFLhqzpS+VbhQn6I9606 rigid:RC7zWVpsTDdYa69qvmjwzMkooNA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P55197 uniprotkb:P29692 intact:EBI-1104952|ensembl:ENSP00000307411|ensembl:ENSP00000366258|ensembl:ENSP00000488569|uniprotkb:Q5JT37|uniprotkb:Q66K63|uniprotkb:B1ANA8|uniprotkb:Q5VX90|intact:EBI-11060398 intact:EBI-358607|uniprotkb:Q969J1|uniprotkb:D3DWK3|intact:EBI-748782|uniprotkb:Q96I38|ensembl:ENSP00000317399|ensembl:ENSP00000378551|ensembl:ENSP00000388261|ensembl:ENSP00000433412|ensembl:ENSP00000433611|ensembl:ENSP00000434448|ensembl:ENSP00000434872|ensembl:ENSP00000436542|ensembl:ENSP00000436933|ensembl:ENSP00000478340|ensembl:ENSP00000479653|ensembl:ENSP00000483527|ensembl:ENSP00000487680|intact:EBI-11048966|uniprotkb:Q4VBZ6|uniprotkb:B4DDU4|uniprotkb:E9PBQ9 psi-mi:af10_human(display_long)|uniprotkb:MLLT10(gene name)|psi-mi:MLLT10(display_short)|uniprotkb:AF10(gene name synonym)|uniprotkb:ALL1-fused gene from chromosome 10 protein(gene name synonym) psi-mi:ef1d_human(display_long)|uniprotkb:EEF1D(gene name)|psi-mi:EEF1D(display_short)|uniprotkb:EF1D(gene name synonym)|uniprotkb:Antigen NY-CO-4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481286|imex:IM-26985-109 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000078403(gene)|ensembl:ENSP00000307411|ensembl:ENSP00000366258|ensembl:ENST00000377072|ensembl:ENSP00000366272|ensembl:ENST00000377091|ensembl:ENSP00000366295|ensembl:ENST00000377100|ensembl:ENSP00000366304|ensembl:ENST00000621220|ensembl:ENSP00000484335|ensembl:ENSP00000488569|ensembl:ENST00000652497|ensembl:ENSP00000498595|refseq:NP_001182556.1|refseq:NP_004632.1|ensembl:ENST00000307729(transcript)|ensembl:ENST00000377059(transcript)|ensembl:ENST00000631589(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|mint:P55197|rcsb pdb:5DAG|rcsb pdb:5DAH|rcsb pdb:6CKN|rcsb pdb:6CKO|rcsb pdb:6JN2|refseq:NP_001182557.1|refseq:NP_001182559.1|refseq:NP_001182555.1|refseq:NP_001311225.1|dip:DIP-37633N refseq:NP_001123528.1|refseq:NP_001123527.1|refseq:NP_001123529.1|refseq:NP_001951.2|refseq:XP_011515207.1|refseq:XP_011515208.1|ensembl:ENST00000419152(transcript)|ensembl:ENST00000529272(transcript)|ensembl:ENST00000530191(transcript)|ensembl:ENST00000530445(transcript)|ensembl:ENST00000531218(transcript)|ensembl:ENST00000533494(transcript)|ensembl:ENST00000534380(transcript)|ensembl:ENST00000614575(transcript)|ensembl:ENST00000615067(transcript)|ensembl:ENST00000615698(transcript)|ensembl:ENST00000632587(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0006414"(translational elongation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0009299"(mRNA transcription)|go:"GO:0010941"(regulation of cell death)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045296"(cadherin binding)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001326(Translation elongation factor EF1B, beta/delta chains, conserved site)|interpro:IPR014038(Translation elongation factor EF1B, beta and delta chains, guanine nucleotide exchange)|interpro:IPR014717(Translation elongation factor EF1B/ribosomal protein S6)|interpro:IPR018940|interpro:IPR036219|mint:P29692|rcsb pdb:2MVM|rcsb pdb:2MVN|rcsb pdb:2N51|rcsb pdb:5JPO|reactome:R-HSA-156842|ensembl:ENSG00000104529(gene)|ensembl:ENSG00000273594(gene)|ensembl:ENST00000317198(transcript)|ensembl:ENST00000395119(transcript)|refseq:NP_001304672.1|refseq:NP_001182132.1|refseq:NP_001276879.1|refseq:XP_006716585.1|refseq:XP_006716586.1|refseq:XP_006716587.1|refseq:XP_006716588.1|refseq:XP_005250880.1|refseq:NP_001317575.1|refseq:XP_016868659.1|refseq:NP_001123525.2|refseq:NP_115754.3 - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:7jWr9+kJgTFVbZvq+BndUhHQstA9606 rogid:9Mzpfofeg2W/GQ/JfjFxcCFJnKg9606 rigid:RC7zWVpsTDdYa69qvmjwzMkooNA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H8S9 uniprotkb:Q4FZB7 intact:EBI-748229|uniprotkb:Q53S34|uniprotkb:Q9H3T5|uniprotkb:Q9HAI0|uniprotkb:Q9NVE2|ensembl:ENSP00000379364 intact:EBI-1047962|uniprotkb:Q3SX56|uniprotkb:Q4V775|uniprotkb:Q6P150|uniprotkb:Q96E44|uniprotkb:Q9BUL0|uniprotkb:Q9H022|uniprotkb:Q9H2K3|uniprotkb:Q9NXV3|uniprotkb:Q9Y393|uniprotkb:B7WNX7|ensembl:ENSP00000305899|ensembl:ENSP00000484858|uniprotkb:A0A0A0MT19 psi-mi:mob1a_human(display_long)|uniprotkb:MOB1A(gene name)|psi-mi:MOB1A(display_short)|uniprotkb:C2orf6(gene name synonym)|uniprotkb:MOB4B(gene name synonym)|uniprotkb:MOBK1B(gene name synonym)|uniprotkb:MOBKL1B(gene name synonym)|uniprotkb:Mob1 alpha(gene name synonym)|uniprotkb:Mob1 homolog 1B(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 1B(gene name synonym) psi-mi:kmt5b_human(display_long)|uniprotkb:[histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:[histone H4]-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:CGI-85(orf name)|uniprotkb:KMT5B(gene name)|psi-mi:KMT5B(display_short)|uniprotkb:Lysine N-methyltransferase 5B(gene name synonym)|uniprotkb:Lysine-specific methyltransferase 5B(gene name synonym)|uniprotkb:SUV420H1(gene name synonym)|uniprotkb:Suppressor of variegation 4-20 homolog 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481304|imex:IM-26985-253 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001304039.1|refseq:NP_001304040.1|refseq:NP_001304041.1|refseq:NP_060691.2|ensembl:ENSG00000114978(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0035329"(hippo signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9H8S9|rcsb pdb:1PI1|rcsb pdb:4J1V|rcsb pdb:4JIZ|rcsb pdb:5BRK|rcsb pdb:5BRM|rcsb pdb:5TWF|rcsb pdb:5TWG|rcsb pdb:5TWH|rcsb pdb:5XQZ|rcsb pdb:6MCP|rcsb pdb:6MCQ|reactome:R-HSA-2028269|ensembl:ENST00000396049(transcript)|dip:DIP-36594N refseq:NP_057112.3|refseq:NP_060105.3|refseq:XP_011543393.1|refseq:XP_011543396.1|refseq:NP_001287838.1|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001214(SET)|interpro:IPR025790|interpro:IPR039977|interpro:IPR041938|interpro:IPR044424|mint:Q4FZB7|rcsb pdb:3S8P|rcsb pdb:5CPR|rcsb pdb:5WBV|reactome:R-HSA-3214841|ensembl:ENSG00000110066(gene)|ensembl:ENST00000304363(transcript)|ensembl:ENST00000615954(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0007517"(muscle organ development)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0034772"(histone H4-K20 dimethylation)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0046872"(metal ion binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|refseq:XP_005274092.2|dip:DIP-48656N|refseq:XP_011543395.1 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Gup4pRYJH3cfC6+XkgI27yiF7g89606 rogid:PtHlCj2DZzd3IA0joU5M307MqM49606 rigid:wdVzgWHtzxyn8KdLL/621UQ7khk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H8S9 uniprotkb:P01040 intact:EBI-748229|uniprotkb:Q53S34|uniprotkb:Q9H3T5|uniprotkb:Q9HAI0|uniprotkb:Q9NVE2|ensembl:ENSP00000379364 intact:EBI-724303|ensembl:ENSP00000264474|uniprotkb:Q6IB90 psi-mi:mob1a_human(display_long)|uniprotkb:MOB1A(gene name)|psi-mi:MOB1A(display_short)|uniprotkb:C2orf6(gene name synonym)|uniprotkb:MOB4B(gene name synonym)|uniprotkb:MOBK1B(gene name synonym)|uniprotkb:MOBKL1B(gene name synonym)|uniprotkb:Mob1 alpha(gene name synonym)|uniprotkb:Mob1 homolog 1B(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 1B(gene name synonym) psi-mi:cyta_human(display_long)|uniprotkb:Cystatin-AS(gene name synonym)|uniprotkb:Stefin-A(gene name synonym)|uniprotkb:CSTA(gene name)|psi-mi:CSTA(display_short)|uniprotkb:STF1(gene name synonym)|uniprotkb:STFA(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481304|imex:IM-26985-253 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001304039.1|refseq:NP_001304040.1|refseq:NP_001304041.1|refseq:NP_060691.2|ensembl:ENSG00000114978(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0035329"(hippo signaling)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005301(Mob1/phocein)|interpro:IPR036703|mint:Q9H8S9|rcsb pdb:1PI1|rcsb pdb:4J1V|rcsb pdb:4JIZ|rcsb pdb:5BRK|rcsb pdb:5BRM|rcsb pdb:5TWF|rcsb pdb:5TWG|rcsb pdb:5TWH|rcsb pdb:5XQZ|rcsb pdb:6MCP|rcsb pdb:6MCQ|reactome:R-HSA-2028269|ensembl:ENST00000396049(transcript)|dip:DIP-36594N refseq:NP_005204.1|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR001713(Proteinase inhibitor I25A, stefin A)|mint:P01040|rcsb pdb:1CYU|rcsb pdb:1CYV|rcsb pdb:1DVC|rcsb pdb:1DVD|rcsb pdb:1GD3|rcsb pdb:1GD4|rcsb pdb:1N9J|rcsb pdb:1NB3|rcsb pdb:1NB5|rcsb pdb:3K9M|rcsb pdb:3KFQ|interpro:IPR018073|rcsb pdb:3KSE|reactome:R-HSA-6809371|ensembl:ENSG00000121552(gene)|ensembl:ENST00000264474(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002020"(protease binding)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0045861"(negative regulation of proteolysis) - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Gup4pRYJH3cfC6+XkgI27yiF7g89606 rogid:SzbpyWUHlOtItIvffzuwhcqFsDI9606 rigid:wdVzgWHtzxyn8KdLL/621UQ7khk false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UBU8 uniprotkb:Q9Y605 intact:EBI-399246|uniprotkb:O95899|uniprotkb:Q5QTS1|uniprotkb:Q6NVX8|uniprotkb:Q86YT7|uniprotkb:Q9HBP6|uniprotkb:Q9NSW5|uniprotkb:B4DKN6|uniprotkb:D3DW88|ensembl:ENSP00000331310|uniprotkb:B7Z6R1 intact:EBI-995714|uniprotkb:B3KVT2|ensembl:ENSP00000318352|ensembl:ENSP00000372024|ensembl:ENSP00000422065|uniprotkb:D3DVT3 psi-mi:mo4l1_human(display_long)|uniprotkb:HSPC008(orf name)|uniprotkb:HSPC061(orf name)|uniprotkb:PP368(orf name)|uniprotkb:MORF4L1(gene name)|psi-mi:MORF4L1(display_short)|uniprotkb:MRG15(gene name synonym)|uniprotkb:MORF-related gene 15 protein(gene name synonym)|uniprotkb:Transcription factor-like protein MRG15(gene name synonym)|uniprotkb:Protein MSL3-1(gene name synonym)|uniprotkb:FWP006(orf name) psi-mi:mofa1_human(display_long)|uniprotkb:PGR1(gene name synonym)|uniprotkb:Protein PGR1(gene name synonym)|uniprotkb:Protein associated with MRG of 14 kDa(gene name synonym)|uniprotkb:MRFAP1(gene name)|psi-mi:MRFAP1(display_short)|uniprotkb:PAM14(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481316|imex:IM-26985-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006782.1|refseq:NP_996670.1|dip:DIP-29017N|refseq:NP_001252532.1|refseq:NP_001252533.1|refseq:NP_001252534.1|ensembl:ENSG00000185787(gene)|ensembl:ENST00000331268(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0016573"(histone acetylation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR008676(MRG)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR026541|interpro:IPR038011|interpro:IPR038217|mint:Q9UBU8|rcsb pdb:2AQL|rcsb pdb:2EFI|rcsb pdb:2F5J|rcsb pdb:2F5K|rcsb pdb:2LKM|rcsb pdb:2N1D|rcsb pdb:6AGO|rcsb pdb:6INE|reactome:R-HSA-3214847 refseq:NP_150638.1|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR029254|mint:Q9Y605|ensembl:ENSG00000179010(gene)|ensembl:ENST00000320912(transcript)|ensembl:ENST00000382581(transcript)|ensembl:ENST00000507420(transcript)|go:"GO:0005654"(nucleoplasm)|refseq:NP_001258982.1 - - comment:"author score: 43" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:28GQifqUMxwR32cneTXH+lpW4gM9606 rogid:qsRG2MjlSzgcyuUj0/45kBNrfw89606 rigid:LEhEri/UAg63rK5y1VHChW/66Fk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UBU8 uniprotkb:Q99417 intact:EBI-399246|uniprotkb:O95899|uniprotkb:Q5QTS1|uniprotkb:Q6NVX8|uniprotkb:Q86YT7|uniprotkb:Q9HBP6|uniprotkb:Q9NSW5|uniprotkb:B4DKN6|uniprotkb:D3DW88|ensembl:ENSP00000331310|uniprotkb:B7Z6R1 intact:EBI-716185|intact:EBI-2559925|uniprotkb:Q5TA64|uniprotkb:Q96HE2|uniprotkb:B2R4N0|ensembl:ENSP00000380702 psi-mi:mo4l1_human(display_long)|uniprotkb:HSPC008(orf name)|uniprotkb:HSPC061(orf name)|uniprotkb:PP368(orf name)|uniprotkb:MORF4L1(gene name)|psi-mi:MORF4L1(display_short)|uniprotkb:MRG15(gene name synonym)|uniprotkb:MORF-related gene 15 protein(gene name synonym)|uniprotkb:Transcription factor-like protein MRG15(gene name synonym)|uniprotkb:Protein MSL3-1(gene name synonym)|uniprotkb:FWP006(orf name) psi-mi:mycbp_human(display_long)|uniprotkb:Associate of Myc 1(gene name synonym)|uniprotkb:MYCBP(gene name)|psi-mi:MYCBP(display_short)|uniprotkb:AMY1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481316|imex:IM-26985-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006782.1|refseq:NP_996670.1|dip:DIP-29017N|refseq:NP_001252532.1|refseq:NP_001252533.1|refseq:NP_001252534.1|ensembl:ENSG00000185787(gene)|ensembl:ENST00000331268(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0016573"(histone acetylation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR008676(MRG)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR026541|interpro:IPR038011|interpro:IPR038217|mint:Q9UBU8|rcsb pdb:2AQL|rcsb pdb:2EFI|rcsb pdb:2F5J|rcsb pdb:2F5K|rcsb pdb:2LKM|rcsb pdb:2N1D|rcsb pdb:6AGO|rcsb pdb:6INE|reactome:R-HSA-3214847 refseq:NP_036465.2|ensembl:ENSG00000214114(gene)|ensembl:ENST00000397572(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007283"(spermatogenesis)|interpro:IPR026060|mint:Q99417|rcsb pdb:2YY0 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:28GQifqUMxwR32cneTXH+lpW4gM9606 rogid:jIStn1A10DDkgTuwVeKpDPJ6tIs9606 rigid:LEhEri/UAg63rK5y1VHChW/66Fk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UBU8 uniprotkb:Q9Y3Y2 intact:EBI-399246|uniprotkb:O95899|uniprotkb:Q5QTS1|uniprotkb:Q6NVX8|uniprotkb:Q86YT7|uniprotkb:Q9HBP6|uniprotkb:Q9NSW5|uniprotkb:B4DKN6|uniprotkb:D3DW88|ensembl:ENSP00000331310|uniprotkb:B7Z6R1 intact:EBI-347794|uniprotkb:Q2VPI9|uniprotkb:Q5T7Y8|uniprotkb:Q5T7Z0|uniprotkb:Q6NSM4|uniprotkb:Q6PB28|uniprotkb:Q8WYT9|uniprotkb:Q9BUC5|uniprotkb:Q9H034|uniprotkb:Q9H2L0|uniprotkb:Q0VAQ8|uniprotkb:D3DV55|uniprotkb:Q5T7Y9|ensembl:ENSP00000357683 psi-mi:mo4l1_human(display_long)|uniprotkb:HSPC008(orf name)|uniprotkb:HSPC061(orf name)|uniprotkb:PP368(orf name)|uniprotkb:MORF4L1(gene name)|psi-mi:MORF4L1(display_short)|uniprotkb:MRG15(gene name synonym)|uniprotkb:MORF-related gene 15 protein(gene name synonym)|uniprotkb:Transcription factor-like protein MRG15(gene name synonym)|uniprotkb:Protein MSL3-1(gene name synonym)|uniprotkb:FWP006(orf name) psi-mi:chtop_human(display_long)|uniprotkb:HT031(orf name)|uniprotkb:PP7704(orf name)|uniprotkb:FOP(gene name synonym)|uniprotkb:CHTOP(gene name)|psi-mi:CHTOP(display_short)|uniprotkb:C1orf77(gene name synonym)|uniprotkb:Friend of PRMT1 protein(gene name synonym)|uniprotkb:Small arginine- and glycine-rich protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481316|imex:IM-26985-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006782.1|refseq:NP_996670.1|dip:DIP-29017N|refseq:NP_001252532.1|refseq:NP_001252533.1|refseq:NP_001252534.1|ensembl:ENSG00000185787(gene)|ensembl:ENST00000331268(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0016573"(histone acetylation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR008676(MRG)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR026541|interpro:IPR038011|interpro:IPR038217|mint:Q9UBU8|rcsb pdb:2AQL|rcsb pdb:2EFI|rcsb pdb:2F5J|rcsb pdb:2F5K|rcsb pdb:2LKM|rcsb pdb:2N1D|rcsb pdb:6AGO|rcsb pdb:6INE|reactome:R-HSA-3214847 refseq:NP_001304006.1|refseq:NP_001193541.1|refseq:NP_056422.2|refseq:NP_001231593.1|ensembl:ENSG00000160679(gene)|ensembl:ENST00000368694(transcript)|go:"GO:0000346"(transcription export complex)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0051096"(positive regulation of helicase activity)|interpro:IPR025715|mint:Q9Y3Y2|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:28GQifqUMxwR32cneTXH+lpW4gM9606 rogid:mNq0QTGQnGABQwIL2S90Hbp3Nm89606 rigid:LEhEri/UAg63rK5y1VHChW/66Fk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UBU8 uniprotkb:P68363 intact:EBI-399246|uniprotkb:O95899|uniprotkb:Q5QTS1|uniprotkb:Q6NVX8|uniprotkb:Q86YT7|uniprotkb:Q9HBP6|uniprotkb:Q9NSW5|uniprotkb:B4DKN6|uniprotkb:D3DW88|ensembl:ENSP00000331310|uniprotkb:B7Z6R1 intact:EBI-487083|intact:EBI-1384226|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:Q27I68|ensembl:ENSP00000336799|uniprotkb:Q8WU19 psi-mi:mo4l1_human(display_long)|uniprotkb:HSPC008(orf name)|uniprotkb:HSPC061(orf name)|uniprotkb:PP368(orf name)|uniprotkb:MORF4L1(gene name)|psi-mi:MORF4L1(display_short)|uniprotkb:MRG15(gene name synonym)|uniprotkb:MORF-related gene 15 protein(gene name synonym)|uniprotkb:Transcription factor-like protein MRG15(gene name synonym)|uniprotkb:Protein MSL3-1(gene name synonym)|uniprotkb:FWP006(orf name) psi-mi:tba1b_human(display_long)|uniprotkb:TUBA1B(gene name)|psi-mi:TUBA1B(display_short)|uniprotkb:Tubulin alpha-ubiquitous chain(gene name synonym)|uniprotkb:Alpha-tubulin ubiquitous(gene name synonym)|uniprotkb:Tubulin K-alpha-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481316|imex:IM-26985-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006782.1|refseq:NP_996670.1|dip:DIP-29017N|refseq:NP_001252532.1|refseq:NP_001252533.1|refseq:NP_001252534.1|ensembl:ENSG00000185787(gene)|ensembl:ENST00000331268(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0016573"(histone acetylation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR008676(MRG)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR026541|interpro:IPR038011|interpro:IPR038217|mint:Q9UBU8|rcsb pdb:2AQL|rcsb pdb:2EFI|rcsb pdb:2F5J|rcsb pdb:2F5K|rcsb pdb:2LKM|rcsb pdb:2N1D|rcsb pdb:6AGO|rcsb pdb:6INE|reactome:R-HSA-3214847 refseq:NP_006073.2|ensembl:ENSG00000123416(gene)|ensembl:ENST00000336023(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-983189|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|go:"GO:0045121"(membrane raft)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68363|rcsb pdb:2E4H|rcsb pdb:5IJ0|rcsb pdb:5IJ9|rcsb pdb:5N5N|rcsb pdb:6E7B|rcsb pdb:6E7C|rcsb pdb:6I2I|go:"GO:0051301"(cell division)|rcsb pdb:6J4V|rcsb pdb:6J8O|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|rcsb pdb:6S8L|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9013407|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-2132295|reactome:R-HSA-9668328 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:28GQifqUMxwR32cneTXH+lpW4gM9606 rogid:D4YpuLCXl/S+53qV7P7sF81aARY9606 rigid:LEhEri/UAg63rK5y1VHChW/66Fk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UBU8 uniprotkb:Q96HT8 intact:EBI-399246|uniprotkb:O95899|uniprotkb:Q5QTS1|uniprotkb:Q6NVX8|uniprotkb:Q86YT7|uniprotkb:Q9HBP6|uniprotkb:Q9NSW5|uniprotkb:B4DKN6|uniprotkb:D3DW88|ensembl:ENSP00000331310|uniprotkb:B7Z6R1 intact:EBI-748896|uniprotkb:Q6NXT8|uniprotkb:Q9P0J5|uniprotkb:B2R6R0|ensembl:ENSP00000318154 psi-mi:mo4l1_human(display_long)|uniprotkb:HSPC008(orf name)|uniprotkb:HSPC061(orf name)|uniprotkb:PP368(orf name)|uniprotkb:MORF4L1(gene name)|psi-mi:MORF4L1(display_short)|uniprotkb:MRG15(gene name synonym)|uniprotkb:MORF-related gene 15 protein(gene name synonym)|uniprotkb:Transcription factor-like protein MRG15(gene name synonym)|uniprotkb:Protein MSL3-1(gene name synonym)|uniprotkb:FWP006(orf name) psi-mi:mr1l1_human(display_long)|uniprotkb:PP784(orf name)|uniprotkb:MRFAP1L1(gene name)|psi-mi:MRFAP1L1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481316|imex:IM-26985-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006782.1|refseq:NP_996670.1|dip:DIP-29017N|refseq:NP_001252532.1|refseq:NP_001252533.1|refseq:NP_001252534.1|ensembl:ENSG00000185787(gene)|ensembl:ENST00000331268(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0016573"(histone acetylation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR008676(MRG)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR026541|interpro:IPR038011|interpro:IPR038217|mint:Q9UBU8|rcsb pdb:2AQL|rcsb pdb:2EFI|rcsb pdb:2F5J|rcsb pdb:2F5K|rcsb pdb:2LKM|rcsb pdb:2N1D|rcsb pdb:6AGO|rcsb pdb:6INE|reactome:R-HSA-3214847 refseq:NP_982287.1|refseq:XP_005247989.1|ensembl:ENSG00000178988(gene)|ensembl:ENST00000320848(transcript)|go:"GO:0042802"(identical protein binding)|interpro:IPR029254|mint:Q96HT8|dip:DIP-29019N - - caution:This sequence has been withdrawn from Uniprot.|crc64:6C914B0B4BEECAE5|comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:28GQifqUMxwR32cneTXH+lpW4gM9606 rogid:hb4enqSS7DeieOByDoLDkXkSlIk9606 rigid:LEhEri/UAg63rK5y1VHChW/66Fk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UBU8 uniprotkb:Q16576 intact:EBI-399246|uniprotkb:O95899|uniprotkb:Q5QTS1|uniprotkb:Q6NVX8|uniprotkb:Q86YT7|uniprotkb:Q9HBP6|uniprotkb:Q9NSW5|uniprotkb:B4DKN6|uniprotkb:D3DW88|ensembl:ENSP00000331310|uniprotkb:B7Z6R1 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 psi-mi:mo4l1_human(display_long)|uniprotkb:HSPC008(orf name)|uniprotkb:HSPC061(orf name)|uniprotkb:PP368(orf name)|uniprotkb:MORF4L1(gene name)|psi-mi:MORF4L1(display_short)|uniprotkb:MRG15(gene name synonym)|uniprotkb:MORF-related gene 15 protein(gene name synonym)|uniprotkb:Transcription factor-like protein MRG15(gene name synonym)|uniprotkb:Protein MSL3-1(gene name synonym)|uniprotkb:FWP006(orf name) psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481316|imex:IM-26985-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006782.1|refseq:NP_996670.1|dip:DIP-29017N|refseq:NP_001252532.1|refseq:NP_001252533.1|refseq:NP_001252534.1|ensembl:ENSG00000185787(gene)|ensembl:ENST00000331268(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0016573"(histone acetylation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR008676(MRG)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR026541|interpro:IPR038011|interpro:IPR038217|mint:Q9UBU8|rcsb pdb:2AQL|rcsb pdb:2EFI|rcsb pdb:2F5J|rcsb pdb:2F5K|rcsb pdb:2LKM|rcsb pdb:2N1D|rcsb pdb:6AGO|rcsb pdb:6INE|reactome:R-HSA-3214847 refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:28GQifqUMxwR32cneTXH+lpW4gM9606 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rigid:LEhEri/UAg63rK5y1VHChW/66Fk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UBU8 uniprotkb:Q92769 intact:EBI-399246|uniprotkb:O95899|uniprotkb:Q5QTS1|uniprotkb:Q6NVX8|uniprotkb:Q86YT7|uniprotkb:Q9HBP6|uniprotkb:Q9NSW5|uniprotkb:B4DKN6|uniprotkb:D3DW88|ensembl:ENSP00000331310|uniprotkb:B7Z6R1 intact:EBI-301821|uniprotkb:Q5SRI8|uniprotkb:Q5SZ86|uniprotkb:Q8NEH4|uniprotkb:B4DL58|ensembl:ENSP00000430432|uniprotkb:E1P561|uniprotkb:B3KRS5 psi-mi:mo4l1_human(display_long)|uniprotkb:HSPC008(orf name)|uniprotkb:HSPC061(orf name)|uniprotkb:PP368(orf name)|uniprotkb:MORF4L1(gene name)|psi-mi:MORF4L1(display_short)|uniprotkb:MRG15(gene name synonym)|uniprotkb:MORF-related gene 15 protein(gene name synonym)|uniprotkb:Transcription factor-like protein MRG15(gene name synonym)|uniprotkb:Protein MSL3-1(gene name synonym)|uniprotkb:FWP006(orf name) psi-mi:hdac2_human(display_long)|uniprotkb:HDAC2(gene name)|psi-mi:HDAC2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481316|imex:IM-26985-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006782.1|refseq:NP_996670.1|dip:DIP-29017N|refseq:NP_001252532.1|refseq:NP_001252533.1|refseq:NP_001252534.1|ensembl:ENSG00000185787(gene)|ensembl:ENST00000331268(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0016573"(histone acetylation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR008676(MRG)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR026541|interpro:IPR038011|interpro:IPR038217|mint:Q9UBU8|rcsb pdb:2AQL|rcsb pdb:2EFI|rcsb pdb:2F5J|rcsb pdb:2F5K|rcsb pdb:2LKM|rcsb pdb:2N1D|rcsb pdb:6AGO|rcsb pdb:6INE|reactome:R-HSA-3214847 go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035094"(response to nicotine)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042220"(response to cocaine)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q92769|rcsb pdb:3MAX|rcsb pdb:4LXZ|rcsb pdb:4LY1|rcsb pdb:5IWG|rcsb pdb:5IX0|rcsb pdb:6G3O|rcsb pdb:6WBW|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|ensembl:ENSG00000196591(gene)|ensembl:ENST00000519065(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|rcsb pdb:6WHN|rcsb pdb:6WHO|rcsb pdb:6WHQ|rcsb pdb:6WHZ|rcsb pdb:6WI3|rcsb pdb:6XDM|rcsb pdb:6XEB|rcsb pdb:6XEC|rcsb pdb:7KBG|rcsb pdb:7KBH|rcsb pdb:7LTG|rcsb pdb:7LTK|rcsb pdb:7LTL|reactome:R-HSA-193670|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9615017|reactome:R-HSA-9619665|reactome:R-HSA-9679191|reactome:R-HSA-983231|rcsb pdb:6WBZ|refseq:NP_001518.3|dip:DIP-24220N|refseq:XP_011534090.1|refseq:XP_016866288.1 - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:28GQifqUMxwR32cneTXH+lpW4gM9606 rogid:K4PpGz9E9/TrQZsgvrJuc+uYCn89606 rigid:LEhEri/UAg63rK5y1VHChW/66Fk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UBU8 uniprotkb:O43175 intact:EBI-399246|uniprotkb:O95899|uniprotkb:Q5QTS1|uniprotkb:Q6NVX8|uniprotkb:Q86YT7|uniprotkb:Q9HBP6|uniprotkb:Q9NSW5|uniprotkb:B4DKN6|uniprotkb:D3DW88|ensembl:ENSP00000331310|uniprotkb:B7Z6R1 intact:EBI-350495|uniprotkb:Q5SZU3|uniprotkb:Q9BQ01|ensembl:ENSP00000493175|ensembl:ENSP00000493382|uniprotkb:B2RD08 psi-mi:mo4l1_human(display_long)|uniprotkb:HSPC008(orf name)|uniprotkb:HSPC061(orf name)|uniprotkb:PP368(orf name)|uniprotkb:MORF4L1(gene name)|psi-mi:MORF4L1(display_short)|uniprotkb:MRG15(gene name synonym)|uniprotkb:MORF-related gene 15 protein(gene name synonym)|uniprotkb:Transcription factor-like protein MRG15(gene name synonym)|uniprotkb:Protein MSL3-1(gene name synonym)|uniprotkb:FWP006(orf name) psi-mi:sera_human(display_long)|uniprotkb:PHGDH(gene name)|psi-mi:PHGDH(display_short)|uniprotkb:PGDH3(gene name synonym)|uniprotkb:2-oxoglutarate reductase(gene name synonym)|uniprotkb:Malate dehydrogenase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481316|imex:IM-26985-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006782.1|refseq:NP_996670.1|dip:DIP-29017N|refseq:NP_001252532.1|refseq:NP_001252533.1|refseq:NP_001252534.1|ensembl:ENSG00000185787(gene)|ensembl:ENST00000331268(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0016573"(histone acetylation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR008676(MRG)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR026541|interpro:IPR038011|interpro:IPR038217|mint:Q9UBU8|rcsb pdb:2AQL|rcsb pdb:2EFI|rcsb pdb:2F5J|rcsb pdb:2F5K|rcsb pdb:2LKM|rcsb pdb:2N1D|rcsb pdb:6AGO|rcsb pdb:6INE|reactome:R-HSA-3214847 refseq:NP_006614.2|go:"GO:0030060"(L-malate dehydrogenase activity)|go:"GO:0031175"(neuron projection development)|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070314"(G1 to G0 transition)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR006236(D-3-phosphoglycerate dehydrogenase)|interpro:IPR029009|interpro:IPR029752|interpro:IPR029753|interpro:IPR036291|mint:O43175|rcsb pdb:2G76|rcsb pdb:5N53|rcsb pdb:5N6C|rcsb pdb:5NZO|rcsb pdb:5NZP|rcsb pdb:5NZQ|rcsb pdb:5OFM|rcsb pdb:5OFV|ensembl:ENSG00000092621(gene)|ensembl:ENST00000641023(transcript)|ensembl:ENST00000641597(transcript)|go:"GO:0004617"(phosphoglycerate dehydrogenase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006544"(glycine metabolic process)|go:"GO:0006564"(L-serine biosynthetic process)|go:"GO:0006566"(threonine metabolic process)|go:"GO:0007420"(brain development)|go:"GO:0009055"(electron transfer activity)|go:"GO:0009448"(gamma-aminobutyric acid metabolic process)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0019530"(taurine metabolic process)|go:"GO:0021510"(spinal cord development)|go:"GO:0021782"(glial cell development)|go:"GO:0021915"(neural tube development)|rcsb pdb:5OFW|rcsb pdb:6CWA|rcsb pdb:6PLF|rcsb pdb:6PLG|rcsb pdb:6RIH|rcsb pdb:6RJ2|rcsb pdb:6RJ3|rcsb pdb:6RJ5|rcsb pdb:6RJ6|rcsb pdb:7CVP|reactome:R-HSA-977347 - - comment:"author score: 28" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:28GQifqUMxwR32cneTXH+lpW4gM9606 rogid:uzg4EVysd7/zLXBurqwTCFMvqiA9606 rigid:LEhEri/UAg63rK5y1VHChW/66Fk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UBU8 uniprotkb:Q86YC2 intact:EBI-399246|uniprotkb:O95899|uniprotkb:Q5QTS1|uniprotkb:Q6NVX8|uniprotkb:Q86YT7|uniprotkb:Q9HBP6|uniprotkb:Q9NSW5|uniprotkb:B4DKN6|uniprotkb:D3DW88|ensembl:ENSP00000331310|uniprotkb:B7Z6R1 intact:EBI-1222653|uniprotkb:Q8N7Y6|uniprotkb:Q8ND31|uniprotkb:Q9H6W1|uniprotkb:A6NIE1|ensembl:ENSP00000261584 psi-mi:mo4l1_human(display_long)|uniprotkb:HSPC008(orf name)|uniprotkb:HSPC061(orf name)|uniprotkb:PP368(orf name)|uniprotkb:MORF4L1(gene name)|psi-mi:MORF4L1(display_short)|uniprotkb:MRG15(gene name synonym)|uniprotkb:MORF-related gene 15 protein(gene name synonym)|uniprotkb:Transcription factor-like protein MRG15(gene name synonym)|uniprotkb:Protein MSL3-1(gene name synonym)|uniprotkb:FWP006(orf name) psi-mi:palb2_human(display_long)|uniprotkb:PALB2(gene name)|psi-mi:PALB2(display_short)|uniprotkb:FANCN(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481316|imex:IM-26985-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006782.1|refseq:NP_996670.1|dip:DIP-29017N|refseq:NP_001252532.1|refseq:NP_001252533.1|refseq:NP_001252534.1|ensembl:ENSG00000185787(gene)|ensembl:ENST00000331268(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0016573"(histone acetylation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR008676(MRG)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR026541|interpro:IPR038011|interpro:IPR038217|mint:Q9UBU8|rcsb pdb:2AQL|rcsb pdb:2EFI|rcsb pdb:2F5J|rcsb pdb:2F5K|rcsb pdb:2LKM|rcsb pdb:2N1D|rcsb pdb:6AGO|rcsb pdb:6INE|reactome:R-HSA-3214847 refseq:NP_078951.2|dip:DIP-38427N|ensembl:ENSG00000083093(gene)|ensembl:ENST00000261584(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0001756"(somitogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007498"(mesoderm development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048568"(embryonic organ development)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031920|interpro:IPR036322|interpro:IPR042417|mint:Q86YC2|rcsb pdb:2W18|rcsb pdb:3EU7|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|go:"GO:0001833"(inner cell mass cell proliferation) - - comment:"author score: 35" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:28GQifqUMxwR32cneTXH+lpW4gM9606 rogid:/CusSIimN2s+1JZ83gI0GtaHdz09606 rigid:LEhEri/UAg63rK5y1VHChW/66Fk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UBU8 uniprotkb:Q9H0E9 intact:EBI-399246|uniprotkb:O95899|uniprotkb:Q5QTS1|uniprotkb:Q6NVX8|uniprotkb:Q86YT7|uniprotkb:Q9HBP6|uniprotkb:Q9NSW5|uniprotkb:B4DKN6|uniprotkb:D3DW88|ensembl:ENSP00000331310|uniprotkb:B7Z6R1 intact:EBI-769266|uniprotkb:O43178|uniprotkb:Q15355|uniprotkb:Q58AB0|uniprotkb:Q59GN0|uniprotkb:Q969M9|intact:EBI-28979295|ensembl:ENSP00000254900 psi-mi:mo4l1_human(display_long)|uniprotkb:HSPC008(orf name)|uniprotkb:HSPC061(orf name)|uniprotkb:PP368(orf name)|uniprotkb:MORF4L1(gene name)|psi-mi:MORF4L1(display_short)|uniprotkb:MRG15(gene name synonym)|uniprotkb:MORF-related gene 15 protein(gene name synonym)|uniprotkb:Transcription factor-like protein MRG15(gene name synonym)|uniprotkb:Protein MSL3-1(gene name synonym)|uniprotkb:FWP006(orf name) psi-mi:brd8_human(display_long)|uniprotkb:p120(gene name synonym)|uniprotkb:Skeletal muscle abundant protein 2(gene name synonym)|uniprotkb:Skeletal muscle abundant protein(gene name synonym)|uniprotkb:Thyroid hormone receptor coactivating protein of 120 kDa(gene name synonym)|uniprotkb:BRD8(gene name)|psi-mi:BRD8(display_short)|uniprotkb:SMAP(gene name synonym)|uniprotkb:SMAP2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481316|imex:IM-26985-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006782.1|refseq:NP_996670.1|dip:DIP-29017N|refseq:NP_001252532.1|refseq:NP_001252533.1|refseq:NP_001252534.1|ensembl:ENSG00000185787(gene)|ensembl:ENST00000331268(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0016573"(histone acetylation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR008676(MRG)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR026541|interpro:IPR038011|interpro:IPR038217|mint:Q9UBU8|rcsb pdb:2AQL|rcsb pdb:2EFI|rcsb pdb:2F5J|rcsb pdb:2F5K|rcsb pdb:2LKM|rcsb pdb:2N1D|rcsb pdb:6AGO|rcsb pdb:6INE|reactome:R-HSA-3214847 refseq:NP_001157798.1|refseq:NP_006687.3|refseq:NP_631938.1|ensembl:ENST00000230901|ensembl:ENSP00000230901|ensembl:ENSP00000254900|ensembl:ENST00000411594|ensembl:ENSP00000394330|refseq:NP_001287890.1|refseq:NP_001287891.1|refseq:NP_001287895.1|dip:DIP-31762N|ensembl:ENSG00000112983(gene)|ensembl:ENST00000254900(transcript)|go:"GO:0000812"(Swr1 complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0016573"(histone acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|interpro:IPR001487(Bromodomain)|interpro:IPR036427|interpro:IPR037966|interpro:IPR038002|mint:Q9H0E9|reactome:R-HSA-3214847|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth) - - comment:"author score: 51" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:28GQifqUMxwR32cneTXH+lpW4gM9606 rogid:RUJbvq7VAMg7fzpCT4Hs6/FPej49606 rigid:LEhEri/UAg63rK5y1VHChW/66Fk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UBU8 uniprotkb:O75182 intact:EBI-399246|uniprotkb:O95899|uniprotkb:Q5QTS1|uniprotkb:Q6NVX8|uniprotkb:Q86YT7|uniprotkb:Q9HBP6|uniprotkb:Q9NSW5|uniprotkb:B4DKN6|uniprotkb:D3DW88|ensembl:ENSP00000331310|uniprotkb:B7Z6R1 intact:EBI-540462|uniprotkb:Q68GC2|uniprotkb:Q6P4B8|uniprotkb:Q8TB34|uniprotkb:Q9BSC8|uniprotkb:Q2NL91|ensembl:ENSP00000369131 psi-mi:mo4l1_human(display_long)|uniprotkb:HSPC008(orf name)|uniprotkb:HSPC061(orf name)|uniprotkb:PP368(orf name)|uniprotkb:MORF4L1(gene name)|psi-mi:MORF4L1(display_short)|uniprotkb:MRG15(gene name synonym)|uniprotkb:MORF-related gene 15 protein(gene name synonym)|uniprotkb:Transcription factor-like protein MRG15(gene name synonym)|uniprotkb:Protein MSL3-1(gene name synonym)|uniprotkb:FWP006(orf name) psi-mi:sin3b_human(display_long)|uniprotkb:Transcriptional corepressor Sin3b(gene name synonym)|uniprotkb:Histone deacetylase complex subunit Sin3b(gene name synonym)|uniprotkb:SIN3B(gene name)|psi-mi:SIN3B(display_short)|uniprotkb:KIAA0700(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481316|imex:IM-26985-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006782.1|refseq:NP_996670.1|dip:DIP-29017N|refseq:NP_001252532.1|refseq:NP_001252533.1|refseq:NP_001252534.1|ensembl:ENSG00000185787(gene)|ensembl:ENST00000331268(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0016573"(histone acetylation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR008676(MRG)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR026541|interpro:IPR038011|interpro:IPR038217|mint:Q9UBU8|rcsb pdb:2AQL|rcsb pdb:2EFI|rcsb pdb:2F5J|rcsb pdb:2F5K|rcsb pdb:2LKM|rcsb pdb:2N1D|rcsb pdb:6AGO|rcsb pdb:6INE|reactome:R-HSA-3214847 refseq:NP_056075.1|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0030849"(autosome)|interpro:IPR003822(Paired amphipathic helix)|interpro:IPR013194(Histone deacetylase interacting)|interpro:IPR031693|go:"GO:0003682"(chromatin binding)|interpro:IPR036600|interpro:IPR039774|mint:O75182|reactome:R-HSA-400206|reactome:R-HSA-427413|reactome:R-HSA-8936459|reactome:R-HSA-9707564|ensembl:ENSG00000127511(gene)|ensembl:ENST00000379803(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000805"(X chromosome)|go:"GO:0000806"(Y chromosome)|go:"GO:0001741"(XY body)|refseq:NP_001284524.1|refseq:NP_001284526.1 - - comment:"author score: 73" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:28GQifqUMxwR32cneTXH+lpW4gM9606 rogid:ney2nq8TMh2sFxskgXr+NgNCl349606 rigid:LEhEri/UAg63rK5y1VHChW/66Fk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UBU8 uniprotkb:Q15014 intact:EBI-399246|uniprotkb:O95899|uniprotkb:Q5QTS1|uniprotkb:Q6NVX8|uniprotkb:Q86YT7|uniprotkb:Q9HBP6|uniprotkb:Q9NSW5|uniprotkb:B4DKN6|uniprotkb:D3DW88|ensembl:ENSP00000331310|uniprotkb:B7Z6R1 intact:EBI-399257|uniprotkb:B3KP92|uniprotkb:Q567V0|uniprotkb:Q8J026|uniprotkb:D3DXA5|ensembl:ENSP00000353643|ensembl:ENSP00000391969|ensembl:ENSP00000410532|ensembl:ENSP00000415476 psi-mi:mo4l1_human(display_long)|uniprotkb:HSPC008(orf name)|uniprotkb:HSPC061(orf name)|uniprotkb:PP368(orf name)|uniprotkb:MORF4L1(gene name)|psi-mi:MORF4L1(display_short)|uniprotkb:MRG15(gene name synonym)|uniprotkb:MORF-related gene 15 protein(gene name synonym)|uniprotkb:Transcription factor-like protein MRG15(gene name synonym)|uniprotkb:Protein MSL3-1(gene name synonym)|uniprotkb:FWP006(orf name) psi-mi:mo4l2_human(display_long)|uniprotkb:MORF4L2(gene name)|psi-mi:MORF4L2(display_short)|uniprotkb:KIAA0026(gene name synonym)|uniprotkb:MRGX(gene name synonym)|uniprotkb:MORF-related gene X protein(gene name synonym)|uniprotkb:Transcription factor-like protein MRGX(gene name synonym)|uniprotkb:Protein MSL3-2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481316|imex:IM-26985-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006782.1|refseq:NP_996670.1|dip:DIP-29017N|refseq:NP_001252532.1|refseq:NP_001252533.1|refseq:NP_001252534.1|ensembl:ENSG00000185787(gene)|ensembl:ENST00000331268(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0016573"(histone acetylation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR008676(MRG)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR026541|interpro:IPR038011|interpro:IPR038217|mint:Q9UBU8|rcsb pdb:2AQL|rcsb pdb:2EFI|rcsb pdb:2F5J|rcsb pdb:2F5K|rcsb pdb:2LKM|rcsb pdb:2N1D|rcsb pdb:6AGO|rcsb pdb:6INE|reactome:R-HSA-3214847 refseq:NP_001135894.1|refseq:NP_001135895.1|refseq:NP_001135896.1|refseq:NP_001135897.1|refseq:NP_001135898.1|refseq:NP_001135899.1|refseq:NP_001135900.1|refseq:NP_001135901.1|refseq:NP_001135902.1|refseq:NP_001135903.1|refseq:NP_001135904.1|refseq:NP_036418.1|refseq:NP_001135890.1|refseq:NP_001135891.1|refseq:NP_001135892.1|refseq:NP_001135893.1|ensembl:ENSG00000123562(gene)|ensembl:ENST00000360458(transcript)|ensembl:ENST00000433176(transcript)|ensembl:ENST00000441076(transcript)|ensembl:ENST00000451301(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006342"|go:"GO:0016573"(histone acetylation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051155"(positive regulation of striated muscle cell differentiation)|interpro:IPR008676(MRG)|interpro:IPR026541|interpro:IPR038012|interpro:IPR038217|mint:Q15014|reactome:R-HSA-3214847 - - comment:"author score: 80" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:28GQifqUMxwR32cneTXH+lpW4gM9606 rogid:7SlnJWNVhfdzirTHBEseWbJQjyU9606 rigid:LEhEri/UAg63rK5y1VHChW/66Fk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UBU8 uniprotkb:Q9NV56 intact:EBI-399246|uniprotkb:O95899|uniprotkb:Q5QTS1|uniprotkb:Q6NVX8|uniprotkb:Q86YT7|uniprotkb:Q9HBP6|uniprotkb:Q9NSW5|uniprotkb:B4DKN6|uniprotkb:D3DW88|ensembl:ENSP00000331310|uniprotkb:B7Z6R1 intact:EBI-399076|uniprotkb:A8C4L5|ensembl:ENSP00000359518 psi-mi:mo4l1_human(display_long)|uniprotkb:HSPC008(orf name)|uniprotkb:HSPC061(orf name)|uniprotkb:PP368(orf name)|uniprotkb:MORF4L1(gene name)|psi-mi:MORF4L1(display_short)|uniprotkb:MRG15(gene name synonym)|uniprotkb:MORF-related gene 15 protein(gene name synonym)|uniprotkb:Transcription factor-like protein MRG15(gene name synonym)|uniprotkb:Protein MSL3-1(gene name synonym)|uniprotkb:FWP006(orf name) psi-mi:mrgbp_human(display_long)|uniprotkb:MRGBP(gene name)|psi-mi:MRGBP(display_short)|uniprotkb:C20orf20(gene name synonym)|uniprotkb:MRG-binding protein(gene name synonym)|uniprotkb:Up-regulated in colon cancer 4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481316|imex:IM-26985-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006782.1|refseq:NP_996670.1|dip:DIP-29017N|refseq:NP_001252532.1|refseq:NP_001252533.1|refseq:NP_001252534.1|ensembl:ENSG00000185787(gene)|ensembl:ENST00000331268(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0016573"(histone acetylation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR008676(MRG)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR026541|interpro:IPR038011|interpro:IPR038217|mint:Q9UBU8|rcsb pdb:2AQL|rcsb pdb:2EFI|rcsb pdb:2F5J|rcsb pdb:2F5K|rcsb pdb:2LKM|rcsb pdb:2N1D|rcsb pdb:6AGO|rcsb pdb:6INE|reactome:R-HSA-3214847 refseq:NP_060740.1|ensembl:ENSG00000101189(gene)|ensembl:ENST00000370487(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016573"(histone acetylation)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|interpro:IPR012423(CT20)|mint:Q9NV56|rcsb pdb:2N1D|reactome:R-HSA-3214847|dip:DIP-29018N - - comment:"author score: 86" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:28GQifqUMxwR32cneTXH+lpW4gM9606 rogid:4bfrpXA+a7207TVMYyOyu9MVmKQ9606 rigid:LEhEri/UAg63rK5y1VHChW/66Fk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UBU8 uniprotkb:Q96QT6 intact:EBI-399246|uniprotkb:O95899|uniprotkb:Q5QTS1|uniprotkb:Q6NVX8|uniprotkb:Q86YT7|uniprotkb:Q9HBP6|uniprotkb:Q9NSW5|uniprotkb:B4DKN6|uniprotkb:D3DW88|ensembl:ENSP00000331310|uniprotkb:B7Z6R1 intact:EBI-2803760|uniprotkb:Q9BV34|uniprotkb:Q9P205|uniprotkb:Q6ZML2|uniprotkb:Q0VAI5|uniprotkb:Q9H7U9|ensembl:ENSP00000329933|uniprotkb:Q2TAK2 psi-mi:mo4l1_human(display_long)|uniprotkb:HSPC008(orf name)|uniprotkb:HSPC061(orf name)|uniprotkb:PP368(orf name)|uniprotkb:MORF4L1(gene name)|psi-mi:MORF4L1(display_short)|uniprotkb:MRG15(gene name synonym)|uniprotkb:MORF-related gene 15 protein(gene name synonym)|uniprotkb:Transcription factor-like protein MRG15(gene name synonym)|uniprotkb:Protein MSL3-1(gene name synonym)|uniprotkb:FWP006(orf name) psi-mi:phf12_human(display_long)|uniprotkb:KIAA1523(gene name synonym)|uniprotkb:PHD factor 1(gene name synonym)|uniprotkb:PHF12(gene name)|psi-mi:PHF12(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481316|imex:IM-26985-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006782.1|refseq:NP_996670.1|dip:DIP-29017N|refseq:NP_001252532.1|refseq:NP_001252533.1|refseq:NP_001252534.1|ensembl:ENSG00000185787(gene)|ensembl:ENST00000331268(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0016573"(histone acetylation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR008676(MRG)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR026541|interpro:IPR038011|interpro:IPR038217|mint:Q9UBU8|rcsb pdb:2AQL|rcsb pdb:2EFI|rcsb pdb:2F5J|rcsb pdb:2F5K|rcsb pdb:2LKM|rcsb pdb:2N1D|rcsb pdb:6AGO|rcsb pdb:6INE|reactome:R-HSA-3214847 refseq:NP_001028733.1|refseq:NP_065940.1|ensembl:ENSG00000109118(gene)|ensembl:ENST00000332830(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016580"(Sin3 complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070822"(Sin3-type complex)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR031966|interpro:IPR038098|interpro:IPR042163|mint:Q96QT6|rcsb pdb:2L9S|rcsb pdb:2LKM|refseq:NP_001277060.1|dip:DIP-59632N - - comment:"author score: 95" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:28GQifqUMxwR32cneTXH+lpW4gM9606 rogid:PSctZ9CGOcztlg6VdcB1jkIOhjo9606 rigid:LEhEri/UAg63rK5y1VHChW/66Fk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UBU8 uniprotkb:Q7Z589 intact:EBI-399246|uniprotkb:O95899|uniprotkb:Q5QTS1|uniprotkb:Q6NVX8|uniprotkb:Q86YT7|uniprotkb:Q9HBP6|uniprotkb:Q9NSW5|uniprotkb:B4DKN6|uniprotkb:D3DW88|ensembl:ENSP00000331310|uniprotkb:B7Z6R1 intact:EBI-6598631|ensembl:ENSP00000334130|ensembl:ENSP00000432327|uniprotkb:Q4G109|uniprotkb:Q8NBU6|uniprotkb:Q8TE50|uniprotkb:Q9H8I9|uniprotkb:Q9NRH0|uniprotkb:B7ZKU0|uniprotkb:B7ZKT8|uniprotkb:B7ZKU2|uniprotkb:Q17RM7 psi-mi:mo4l1_human(display_long)|uniprotkb:HSPC008(orf name)|uniprotkb:HSPC061(orf name)|uniprotkb:PP368(orf name)|uniprotkb:MORF4L1(gene name)|psi-mi:MORF4L1(display_short)|uniprotkb:MRG15(gene name synonym)|uniprotkb:MORF-related gene 15 protein(gene name synonym)|uniprotkb:Transcription factor-like protein MRG15(gene name synonym)|uniprotkb:Protein MSL3-1(gene name synonym)|uniprotkb:FWP006(orf name) psi-mi:emsy_human(display_long)|uniprotkb:EMSY(gene name)|psi-mi:EMSY(display_short)|uniprotkb:C11orf30(gene name synonym)|uniprotkb:GL002(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481316|imex:IM-26985-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006782.1|refseq:NP_996670.1|dip:DIP-29017N|refseq:NP_001252532.1|refseq:NP_001252533.1|refseq:NP_001252534.1|ensembl:ENSG00000185787(gene)|ensembl:ENST00000331268(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0016573"(histone acetylation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR008676(MRG)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR026541|interpro:IPR038011|interpro:IPR038217|mint:Q9UBU8|rcsb pdb:2AQL|rcsb pdb:2EFI|rcsb pdb:2F5J|rcsb pdb:2F5K|rcsb pdb:2LKM|rcsb pdb:2N1D|rcsb pdb:6AGO|rcsb pdb:6INE|reactome:R-HSA-3214847 refseq:NP_001287871.1|refseq:NP_001287872.1|refseq:NP_001287873.1|ensembl:ENST00000334736(transcript)|ensembl:ENST00000529032(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0042802"(identical protein binding)|interpro:IPR005491(ENT)|interpro:IPR033482|interpro:IPR036142|mint:Q7Z589|rcsb pdb:1UTU|ensembl:ENSG00000158636(gene)|rcsb pdb:1UZ3|rcsb pdb:2FMM|refseq:NP_064578.2|ensembl:ENSP00000433634|ensembl:ENST00000533988|ensembl:ENSP00000434665|ensembl:ENSP00000334130|ensembl:ENST00000524767|ensembl:ENSP00000433205|ensembl:ENST00000525038|ensembl:ENSP00000436968|ensembl:ENST00000525919|ensembl:ENSP00000432010|ensembl:ENSP00000432327|ensembl:ENST00000533248|dip:DIP-29099N - - comment:"author score: 102" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:28GQifqUMxwR32cneTXH+lpW4gM9606 rogid:AlagiKsle+RG5HUine4x/QddsJc9606 rigid:LEhEri/UAg63rK5y1VHChW/66Fk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UBU8 uniprotkb:Q8WUU5 intact:EBI-399246|uniprotkb:O95899|uniprotkb:Q5QTS1|uniprotkb:Q6NVX8|uniprotkb:Q86YT7|uniprotkb:Q9HBP6|uniprotkb:Q9NSW5|uniprotkb:B4DKN6|uniprotkb:D3DW88|ensembl:ENSP00000331310|uniprotkb:B7Z6R1 intact:EBI-3916882|uniprotkb:D6W5Q5|uniprotkb:Q9H689|uniprotkb:Q8N5Y5|uniprotkb:Q99995|uniprotkb:B2RE37|ensembl:ENSP00000287957 psi-mi:mo4l1_human(display_long)|uniprotkb:HSPC008(orf name)|uniprotkb:HSPC061(orf name)|uniprotkb:PP368(orf name)|uniprotkb:MORF4L1(gene name)|psi-mi:MORF4L1(display_short)|uniprotkb:MRG15(gene name synonym)|uniprotkb:MORF-related gene 15 protein(gene name synonym)|uniprotkb:Transcription factor-like protein MRG15(gene name synonym)|uniprotkb:Protein MSL3-1(gene name synonym)|uniprotkb:FWP006(orf name) psi-mi:gatd1_human(display_long)|uniprotkb:GATAD1(gene name)|psi-mi:GATAD1(display_short)|uniprotkb:ODAG(gene name synonym)|uniprotkb:Ocular development-associated gene protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481316|imex:IM-26985-41 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006782.1|refseq:NP_996670.1|dip:DIP-29017N|refseq:NP_001252532.1|refseq:NP_001252533.1|refseq:NP_001252534.1|ensembl:ENSG00000185787(gene)|ensembl:ENST00000331268(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0016573"(histone acetylation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR008676(MRG)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR026541|interpro:IPR038011|interpro:IPR038217|mint:Q9UBU8|rcsb pdb:2AQL|rcsb pdb:2EFI|rcsb pdb:2F5J|rcsb pdb:2F5K|rcsb pdb:2LKM|rcsb pdb:2N1D|rcsb pdb:6AGO|rcsb pdb:6INE|reactome:R-HSA-3214847 refseq:NP_066990.3|ensembl:ENSG00000157259(gene)|ensembl:ENST00000287957(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR039050|mint:Q8WUU5 - - comment:"author score: 111" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:28GQifqUMxwR32cneTXH+lpW4gM9606 rogid:mwq5yOlZTelKYR0VGr822k9K0Nk9606 rigid:LEhEri/UAg63rK5y1VHChW/66Fk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P49959 uniprotkb:O60934 intact:EBI-396513|uniprotkb:O43475|uniprotkb:B3KTC7|ensembl:ENSP00000325863 intact:EBI-494844|uniprotkb:O60672|uniprotkb:Q32NF7|uniprotkb:Q53FM6|uniprotkb:Q63HR6|uniprotkb:Q7LDM2|uniprotkb:B2R626|uniprotkb:B2RNC5|ensembl:ENSP00000265433 psi-mi:mre11_human(display_long)|uniprotkb:MRE11(gene name)|psi-mi:MRE11(display_short)|uniprotkb:Double-strand break repair protein MRE11A(gene name synonym)|uniprotkb:HNGS1(gene name synonym)|uniprotkb:MRE11A(gene name synonym)|uniprotkb:Meiotic recombination 11 homolog 1(gene name synonym)|uniprotkb:Meiotic recombination 11 homolog A(gene name synonym) psi-mi:nbn_human(display_long)|uniprotkb:Nijmegen breakage syndrome protein 1(gene name synonym)|uniprotkb:Cell cycle regulatory protein p95(gene name synonym)|uniprotkb:NBN(gene name)|psi-mi:NBN(display_short)|uniprotkb:NBS1(gene name synonym)|uniprotkb:NBS(gene name synonym)|uniprotkb:P95(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481370|imex:IM-26985-489 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005581.2|refseq:NP_005582.1|refseq:XP_011541139.1|refseq:XP_016873261.1|dip:DIP-33238N|ensembl:ENSG00000020922(gene)|ensembl:ENST00000323929(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000019"(regulation of mitotic recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0016605"(PML body)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0097552"(mitochondrial double-strand break repair via homologous recombination)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|interpro:IPR003701(DNA repair exonuclease)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR007281(Mre11, DNA-binding)|interpro:IPR029052|interpro:IPR038487|interpro:IPR041796|mint:P49959|rcsb pdb:3T1I|reactome:R-HSA-1834949|reactome:R-HSA-2559586|reactome:R-HSA-3270619|reactome:R-HSA-5685938|reactome:R-HSA-5685939|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446 refseq:NP_002476.2|refseq:NP_001019859.1|refseq:XP_011515347.1|dip:DIP-33605N|ensembl:ENSG00000104320(gene)|ensembl:ENST00000265433(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001832"(blastocyst growth)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016605"(PML body)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042770"(signal transduction in response to DNA damage)|go:"GO:0045190"(isotype switching)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090656"(t-circle formation)|go:"GO:0090737"(telomere maintenance via telomere trimming)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1904354"(negative regulation of telomere capping)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR013908(DNA repair Nbs1, C-terminal)|interpro:IPR016592(Nibrin)|interpro:IPR032429|interpro:IPR036420|interpro:IPR040227|interpro:IPR043014|mint:O60934|rcsb pdb:5WQD|reactome:R-HSA-2559586|reactome:R-HSA-5685938|reactome:R-HSA-5685939|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616 - - comment:"author score: 35" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:fgwgA0BcNZ9phGBaOSYjkldDgeI9606 rogid:CTx61/3iHRb2kWfb5u/CSye5A2k9606 rigid:MsWVyU4qoXTuh61z4yjtfoPb7bw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P49959 uniprotkb:Q92878 intact:EBI-396513|uniprotkb:O43475|uniprotkb:B3KTC7|ensembl:ENSP00000325863 intact:EBI-495494|uniprotkb:O43254|uniprotkb:Q6GMT7|uniprotkb:Q6P5X3|uniprotkb:Q9UP86|uniprotkb:B9EGF5|ensembl:ENSP00000368100 psi-mi:mre11_human(display_long)|uniprotkb:MRE11(gene name)|psi-mi:MRE11(display_short)|uniprotkb:Double-strand break repair protein MRE11A(gene name synonym)|uniprotkb:HNGS1(gene name synonym)|uniprotkb:MRE11A(gene name synonym)|uniprotkb:Meiotic recombination 11 homolog 1(gene name synonym)|uniprotkb:Meiotic recombination 11 homolog A(gene name synonym) psi-mi:rad50_human(display_long)|uniprotkb:RAD50(gene name)|psi-mi:RAD50(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481370|imex:IM-26985-489 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005581.2|refseq:NP_005582.1|refseq:XP_011541139.1|refseq:XP_016873261.1|dip:DIP-33238N|ensembl:ENSG00000020922(gene)|ensembl:ENST00000323929(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000019"(regulation of mitotic recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0016605"(PML body)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0097552"(mitochondrial double-strand break repair via homologous recombination)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|interpro:IPR003701(DNA repair exonuclease)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR007281(Mre11, DNA-binding)|interpro:IPR029052|interpro:IPR038487|interpro:IPR041796|mint:P49959|rcsb pdb:3T1I|reactome:R-HSA-1834949|reactome:R-HSA-2559586|reactome:R-HSA-3270619|reactome:R-HSA-5685938|reactome:R-HSA-5685939|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446 refseq:NP_005723.2|dip:DIP-33606N|ensembl:ENSG00000113522(gene)|ensembl:ENST00000378823(transcript)|go:"GO:0000019"(regulation of mitotic recombination)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003691"(double-stranded telomeric DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:1904354"(negative regulation of telomere capping)|interpro:IPR013134(Zinc hook, Rad50)|interpro:IPR027417|interpro:IPR038729|mint:Q92878|rcsb pdb:5GOX|reactome:R-HSA-2559586|reactome:R-HSA-5685938|reactome:R-HSA-5685939|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446|interpro:IPR004584(Recombination/repair protein Rad50) - - comment:"author score: 52" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:fgwgA0BcNZ9phGBaOSYjkldDgeI9606 rogid:yZsT5GcpA9HeFMoK4Jb1HYhrdKQ9606 rigid:MsWVyU4qoXTuh61z4yjtfoPb7bw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H081 uniprotkb:Q8NG31 intact:EBI-1001205|uniprotkb:Q96N24|ensembl:ENSP00000370557|ensembl:ENSP00000461252|ensembl:ENSP00000484532 intact:EBI-1001161|intact:EBI-2555927|uniprotkb:Q8NHE1|uniprotkb:Q8WXA6|uniprotkb:Q9HCK2|uniprotkb:Q9NR92|ensembl:ENSP00000335463 psi-mi:mis12_human(display_long)|uniprotkb:MIS12(gene name)|psi-mi:MIS12(display_short) psi-mi:knl1_human(display_long)|uniprotkb:KNL1(gene name)|psi-mi:KNL1(display_short)|uniprotkb:ALL1-fused gene from chromosome 15q14 protein(gene name synonym)|uniprotkb:Bub-linking kinetochore protein(gene name synonym)|uniprotkb:CASC5(gene name synonym)|uniprotkb:Cancer susceptibility candidate gene 5 protein(gene name synonym)|uniprotkb:Cancer/testis antigen 29(gene name synonym)|uniprotkb:KIAA1570(gene name synonym)|uniprotkb:Kinetochore-null protein 1(gene name synonym)|uniprotkb:Protein CASC5(gene name synonym)|uniprotkb:Protein D40/AF15q14(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481244|imex:IM-26985-555 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245146.1|refseq:NP_001245147.1|refseq:NP_001245148.1|refseq:NP_001245149.1|refseq:XP_016880522.1|refseq:XP_016880523.1|refseq:XP_016880524.1|refseq:NP_076944.1|ensembl:ENSG00000167842(gene)|ensembl:ENST00000381165(transcript)|ensembl:ENST00000573759(transcript)|ensembl:ENST00000611091(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR008685(Mis12)|mint:Q9H081|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-5663220|refseq:XP_005256854.1 ensembl:ENSG00000137812(gene)|ensembl:ENST00000346991(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001675"(acrosome assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016604"(nuclear body)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|interpro:IPR037388|interpro:IPR040850|interpro:IPR043651|mint:Q8NG31|rcsb pdb:3SI5|rcsb pdb:4A1G|rcsb pdb:4NF9|rcsb pdb:4NFA|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-606279|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_653091.3|refseq:NP_733468.3|ensembl:ENSP00000335463|ensembl:ENST00000399668|ensembl:ENSP00000382576|dip:DIP-36474N - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:1qNMwDq3AYOWnRnPa2u3yt7O4109606 rogid:VrKgxXm7DGkpFhJjZ98oQhkr5Eo9606 rigid:Y9SPFQ7EkUZ80pEhDZa+coV+fRc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H081 uniprotkb:Q9HBM1 intact:EBI-1001205|uniprotkb:Q96N24|ensembl:ENSP00000370557|ensembl:ENSP00000461252|ensembl:ENSP00000484532 intact:EBI-999909|ensembl:ENSP00000282074|ensembl:ENSP00000481354|ensembl:ENSP00000483050|uniprotkb:D3DPC0|uniprotkb:A8K4X8 psi-mi:mis12_human(display_long)|uniprotkb:MIS12(gene name)|psi-mi:MIS12(display_short) psi-mi:spc25_human(display_long)|uniprotkb:AD024(orf name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)|uniprotkb:SPBC25(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481244|imex:IM-26985-555 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245146.1|refseq:NP_001245147.1|refseq:NP_001245148.1|refseq:NP_001245149.1|refseq:XP_016880522.1|refseq:XP_016880523.1|refseq:XP_016880524.1|refseq:NP_076944.1|ensembl:ENSG00000167842(gene)|ensembl:ENST00000381165(transcript)|ensembl:ENST00000573759(transcript)|ensembl:ENST00000611091(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR008685(Mis12)|mint:Q9H081|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-5663220|refseq:XP_005256854.1 refseq:NP_065726.1|ensembl:ENSG00000277909(gene)|ensembl:ENST00000282074(transcript)|ensembl:ENST00000611144(transcript)|ensembl:ENST00000616584(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|interpro:IPR013255(Kinetochore-Ndc80 subunit Spc25)|mint:Q9HBM1|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENSG00000152253(gene)|dip:DIP-35753N - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:1qNMwDq3AYOWnRnPa2u3yt7O4109606 rogid:qR1LJPKAJwXtOdzKs4Zg0PqJrBM9606 rigid:Y9SPFQ7EkUZ80pEhDZa+coV+fRc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H081 uniprotkb:O95229 intact:EBI-1001205|uniprotkb:Q96N24|ensembl:ENSP00000370557|ensembl:ENSP00000461252|ensembl:ENSP00000484532 intact:EBI-1001132|uniprotkb:Q9BWD0|ensembl:ENSP00000363055|ensembl:ENSP00000378801|uniprotkb:Q0D2I3|uniprotkb:A6NNV6 psi-mi:mis12_human(display_long)|uniprotkb:MIS12(gene name)|psi-mi:MIS12(display_short) psi-mi:zwint_human(display_long)|uniprotkb:ZW10-interacting protein 1(gene name synonym)|uniprotkb:ZWINT(gene name)|psi-mi:ZWINT(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481244|imex:IM-26985-555 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245146.1|refseq:NP_001245147.1|refseq:NP_001245148.1|refseq:NP_001245149.1|refseq:XP_016880522.1|refseq:XP_016880523.1|refseq:XP_016880524.1|refseq:NP_076944.1|ensembl:ENSG00000167842(gene)|ensembl:ENST00000381165(transcript)|ensembl:ENST00000573759(transcript)|ensembl:ENST00000611091(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR008685(Mis12)|mint:Q9H081|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-5663220|refseq:XP_005256854.1 refseq:NP_001005413.1|refseq:NP_008988.2|refseq:NP_127490.1|go:"GO:0030425"(dendrite)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051301"(cell division)|ensembl:ENSG00000122952(gene)|go:"GO:0051649"(establishment of localization in cell)|interpro:IPR029092|ensembl:ENST00000373944(transcript)|ensembl:ENST00000395405(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|mint:O95229|go:"GO:0005737"(cytoplasm)|reactome:R-HSA-141444|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|reactome:R-HSA-2467813|go:"GO:0016604"(nuclear body)|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025 - - comment:"author score: 27" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:1qNMwDq3AYOWnRnPa2u3yt7O4109606 rogid:iQ5h+pikwo8Yu1MnEjxLtkGg1NE9606 rigid:Y9SPFQ7EkUZ80pEhDZa+coV+fRc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H081 uniprotkb:Q8NBT2 intact:EBI-1001205|uniprotkb:Q96N24|ensembl:ENSP00000370557|ensembl:ENSP00000461252|ensembl:ENSP00000484532 intact:EBI-999900|uniprotkb:C9JGC4|ensembl:ENSP00000465075|uniprotkb:B4DZZ7 psi-mi:mis12_human(display_long)|uniprotkb:MIS12(gene name)|psi-mi:MIS12(display_short) psi-mi:spc24_human(display_long)|uniprotkb:SPBC24(gene name synonym)|uniprotkb:SPC24(gene name)|psi-mi:SPC24(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481244|imex:IM-26985-555 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245146.1|refseq:NP_001245147.1|refseq:NP_001245148.1|refseq:NP_001245149.1|refseq:XP_016880522.1|refseq:XP_016880523.1|refseq:XP_016880524.1|refseq:NP_076944.1|ensembl:ENSG00000167842(gene)|ensembl:ENST00000381165(transcript)|ensembl:ENST00000573759(transcript)|ensembl:ENST00000611091(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR008685(Mis12)|mint:Q9H081|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-5663220|refseq:XP_005256854.1 refseq:NP_872319.1|ensembl:ENSG00000161888(gene)|ensembl:ENST00000592540(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|mint:Q8NBT2|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001303960.1|refseq:NP_001303962.1|refseq:XP_005259810.1|dip:DIP-35754N - - comment:"author score: 29" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:1qNMwDq3AYOWnRnPa2u3yt7O4109606 rogid:ANMEuzMkpwcbiSjx6OaHAK8vVcA9606 rigid:Y9SPFQ7EkUZ80pEhDZa+coV+fRc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H081 uniprotkb:Q9NRX2 intact:EBI-1001205|uniprotkb:Q96N24|ensembl:ENSP00000370557|ensembl:ENSP00000461252|ensembl:ENSP00000484532 intact:EBI-7825154|ensembl:ENSP00000288937|uniprotkb:Q6IAH8|uniprotkb:Q9C066|uniprotkb:Q96Q53|uniprotkb:D3DQU3|intact:MINT-3064942 psi-mi:mis12_human(display_long)|uniprotkb:MIS12(gene name)|psi-mi:MIS12(display_short) psi-mi:rm17_human(display_long)|uniprotkb:Mitochondrial large ribosomal subunit protein bL17m(gene name synonym)|uniprotkb:MRPL17(gene name)|psi-mi:MRPL17(display_short)|uniprotkb:LIP2(gene name synonym)|uniprotkb:LYST-interacting protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481244|imex:IM-26985-555 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245146.1|refseq:NP_001245147.1|refseq:NP_001245148.1|refseq:NP_001245149.1|refseq:XP_016880522.1|refseq:XP_016880523.1|refseq:XP_016880524.1|refseq:NP_076944.1|ensembl:ENSG00000167842(gene)|ensembl:ENST00000381165(transcript)|ensembl:ENST00000573759(transcript)|ensembl:ENST00000611091(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR008685(Mis12)|mint:Q9H081|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-5663220|refseq:XP_005256854.1 ensembl:ENSG00000158042(gene)|ensembl:ENST00000288937(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0019904"(protein domain specific binding)|interpro:IPR000456(Ribosomal protein L17)|interpro:IPR036373|mint:Q9NRX2|rcsb pdb:2CQM|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:7OF7|refseq:NP_071344.1 - - comment:mint|comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:1qNMwDq3AYOWnRnPa2u3yt7O4109606 rogid:9IL43XtZbhcbaI7Gkq3X6O1M3XE9606 rigid:Y9SPFQ7EkUZ80pEhDZa+coV+fRc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H081 uniprotkb:Q9UJV8 intact:EBI-1001205|uniprotkb:Q96N24|ensembl:ENSP00000370557|ensembl:ENSP00000461252|ensembl:ENSP00000484532 intact:EBI-25478180|ensembl:ENSP00000418721|ensembl:ENSP00000466881|uniprotkb:Q8TE64 psi-mi:mis12_human(display_long)|uniprotkb:MIS12(gene name)|psi-mi:MIS12(display_short) psi-mi:purg_human(display_long)|uniprotkb:PURG(gene name)|psi-mi:PURG(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481244|imex:IM-26985-555 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245146.1|refseq:NP_001245147.1|refseq:NP_001245148.1|refseq:NP_001245149.1|refseq:XP_016880522.1|refseq:XP_016880523.1|refseq:XP_016880524.1|refseq:NP_076944.1|ensembl:ENSG00000167842(gene)|ensembl:ENST00000381165(transcript)|ensembl:ENST00000573759(transcript)|ensembl:ENST00000611091(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR008685(Mis12)|mint:Q9H081|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-5663220|refseq:XP_005256854.1 ensembl:ENSG00000172733(gene)|ensembl:ENST00000475541(transcript)|ensembl:ENST00000523392(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032422"(purine-rich negative regulatory element binding)|interpro:IPR006628(PUR-alpha/beta/gamma, DNA/RNA-binding)|interpro:IPR030501|mint:Q9UJV8|refseq:NP_001015508.1|refseq:NP_001310240.1|refseq:NP_001310241.1|refseq:NP_037489.1 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:1qNMwDq3AYOWnRnPa2u3yt7O4109606 rogid:L4p5p28XV86riOUCM/xZYzXXtlA9606 rigid:Y9SPFQ7EkUZ80pEhDZa+coV+fRc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H081 uniprotkb:Q9BYC9 intact:EBI-1001205|uniprotkb:Q96N24|ensembl:ENSP00000370557|ensembl:ENSP00000461252|ensembl:ENSP00000484532 intact:EBI-714361|uniprotkb:B2RE41|ensembl:ENSP00000341082|uniprotkb:B7Z746 psi-mi:mis12_human(display_long)|uniprotkb:MIS12(gene name)|psi-mi:MIS12(display_short) psi-mi:rm20_human(display_long)|uniprotkb:MRPL20(gene name)|psi-mi:MRPL20(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein bL20m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481244|imex:IM-26985-555 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245146.1|refseq:NP_001245147.1|refseq:NP_001245148.1|refseq:NP_001245149.1|refseq:XP_016880522.1|refseq:XP_016880523.1|refseq:XP_016880524.1|refseq:NP_076944.1|ensembl:ENSG00000167842(gene)|ensembl:ENST00000381165(transcript)|ensembl:ENST00000573759(transcript)|ensembl:ENST00000611091(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR008685(Mis12)|mint:Q9H081|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-5663220|refseq:XP_005256854.1 rcsb pdb:7OF4|rcsb pdb:7OG4|refseq:NP_060441.2|ensembl:ENSG00000242485(gene)|ensembl:ENST00000344843(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|interpro:IPR005813(Ribosomal protein L20)|interpro:IPR035566|mint:Q9BYC9|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:6VMI|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:1qNMwDq3AYOWnRnPa2u3yt7O4109606 rogid:x96Ntk82ZbcbF8ksg84k0sHgINc9606 rigid:Y9SPFQ7EkUZ80pEhDZa+coV+fRc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H081 uniprotkb:Q9ULX9 intact:EBI-1001205|uniprotkb:Q96N24|ensembl:ENSP00000370557|ensembl:ENSP00000461252|ensembl:ENSP00000484532 intact:EBI-721128|uniprotkb:B4DV49|uniprotkb:Q9Y525|ensembl:ENSP00000345393|ensembl:ENSP00000384094|ensembl:ENSP00000388882|ensembl:ENSP00000442060 psi-mi:mis12_human(display_long)|uniprotkb:MIS12(gene name)|psi-mi:MIS12(display_short) psi-mi:maff_human(display_long)|uniprotkb:V-maf musculoaponeurotic fibrosarcoma oncogene homolog F(gene name synonym)|uniprotkb:MAFF(gene name)|psi-mi:MAFF(display_short)|uniprotkb:U-Maf(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481244|imex:IM-26985-555 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245146.1|refseq:NP_001245147.1|refseq:NP_001245148.1|refseq:NP_001245149.1|refseq:XP_016880522.1|refseq:XP_016880523.1|refseq:XP_016880524.1|refseq:NP_076944.1|ensembl:ENSG00000167842(gene)|ensembl:ENST00000381165(transcript)|ensembl:ENST00000573759(transcript)|ensembl:ENST00000611091(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR008685(Mis12)|mint:Q9H081|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-5663220|refseq:XP_005256854.1 refseq:NP_001155044.1|refseq:NP_001155045.1|refseq:NP_001155046.1|refseq:NP_036455.1|ensembl:ENSG00000185022(gene)|ensembl:ENST00000338483(transcript)|ensembl:ENST00000407965(transcript)|ensembl:ENST00000426621(transcript)|ensembl:ENST00000538320(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007567"(parturition)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045604"(regulation of epidermal cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR024874|interpro:IPR033531|mint:Q9ULX9|reactome:R-HSA-983231 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:1qNMwDq3AYOWnRnPa2u3yt7O4109606 rogid:gMt7XusD+WbsF+JZ4vxJgdGJXO89606 rigid:Y9SPFQ7EkUZ80pEhDZa+coV+fRc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H081 uniprotkb:Q13405 intact:EBI-1001205|uniprotkb:Q96N24|ensembl:ENSP00000370557|ensembl:ENSP00000461252|ensembl:ENSP00000484532 intact:EBI-5325200|ensembl:ENSP00000279242|ensembl:ENSP00000434190|uniprotkb:B2R4G6 psi-mi:mis12_human(display_long)|uniprotkb:MIS12(gene name)|psi-mi:MIS12(display_short) psi-mi:rm49_human(display_long)|uniprotkb:Mitochondrial large ribosomal subunit protein mL49(gene name synonym)|uniprotkb:MRPL49(gene name)|psi-mi:MRPL49(display_short)|uniprotkb:C11orf4(gene name synonym)|uniprotkb:NOF1(gene name synonym)|uniprotkb:Neighbor of FAU(gene name synonym)|uniprotkb:Protein NOF1(gene name synonym)|uniprotkb:OK/SW-cl.67(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481244|imex:IM-26985-555 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245146.1|refseq:NP_001245147.1|refseq:NP_001245148.1|refseq:NP_001245149.1|refseq:XP_016880522.1|refseq:XP_016880523.1|refseq:XP_016880524.1|refseq:NP_076944.1|ensembl:ENSG00000167842(gene)|ensembl:ENST00000381165(transcript)|ensembl:ENST00000573759(transcript)|ensembl:ENST00000611091(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR008685(Mis12)|mint:Q9H081|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-5663220|refseq:XP_005256854.1 interpro:IPR007740(Ribosomal protein L49/IMG2)|mint:Q13405|rcsb pdb:3J7Y|ensembl:ENSG00000149792(gene)|ensembl:ENST00000279242(transcript)|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|ensembl:ENST00000526319(transcript)|go:"GO:0003735"(structural constituent of ribosome)|rcsb pdb:6I9R|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|go:"GO:0005762"(mitochondrial large ribosomal subunit)|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|go:"GO:0006412"(translation)|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|rcsb pdb:7OF6|reactome:R-HSA-5419276|refseq:NP_004918.1 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:1qNMwDq3AYOWnRnPa2u3yt7O4109606 rogid:rSs3oQ/ABEywPjx7fwVEuT6fsdQ9606 rigid:Y9SPFQ7EkUZ80pEhDZa+coV+fRc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H081 uniprotkb:P58557 intact:EBI-1001205|uniprotkb:Q96N24|ensembl:ENSP00000370557|ensembl:ENSP00000461252|ensembl:ENSP00000484532 intact:EBI-2114647|uniprotkb:D3DSN2|uniprotkb:B7WPA9|uniprotkb:B7WPF7|ensembl:ENSP00000329614|ensembl:ENSP00000380805|ensembl:ENSP00000380813 psi-mi:mis12_human(display_long)|uniprotkb:MIS12(gene name)|psi-mi:MIS12(display_short) psi-mi:ybey_human(display_long)|uniprotkb:YBEY(gene name)|psi-mi:YBEY(display_short)|uniprotkb:C21orf57(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481244|imex:IM-26985-555 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245146.1|refseq:NP_001245147.1|refseq:NP_001245148.1|refseq:NP_001245149.1|refseq:XP_016880522.1|refseq:XP_016880523.1|refseq:XP_016880524.1|refseq:NP_076944.1|ensembl:ENSG00000167842(gene)|ensembl:ENST00000381165(transcript)|ensembl:ENST00000573759(transcript)|ensembl:ENST00000611091(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR008685(Mis12)|mint:Q9H081|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-5663220|refseq:XP_005256854.1 refseq:NP_478061.1|refseq:NP_001300951.1|refseq:NP_001300952.1|refseq:NP_001300953.1|refseq:NP_001300954.1|refseq:NP_001300955.1|ensembl:ENSG00000182362(gene)|ensembl:ENST00000329319(transcript)|ensembl:ENST00000397691(transcript)|ensembl:ENST00000397701(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0006364"(rRNA processing)|go:"GO:0046872"(metal ion binding)|interpro:IPR002036(Protein of unknown function UPF0054)|interpro:IPR020549|interpro:IPR023091|mint:P58557 - - comment:"author score: 34" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:1qNMwDq3AYOWnRnPa2u3yt7O4109606 rogid:VOjeUF0iThxy1T2ywZGHB8ILorc9606 rigid:Y9SPFQ7EkUZ80pEhDZa+coV+fRc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H081 uniprotkb:Q96IY1 intact:EBI-1001205|uniprotkb:Q96N24|ensembl:ENSP00000370557|ensembl:ENSP00000461252|ensembl:ENSP00000484532 intact:EBI-2554690|uniprotkb:Q9H2M5|uniprotkb:Q5SY75|uniprotkb:Q9Y415|uniprotkb:Q9NRN8|ensembl:ENSP00000355944|uniprotkb:E7ETD5 psi-mi:mis12_human(display_long)|uniprotkb:MIS12(gene name)|psi-mi:MIS12(display_short) psi-mi:nsl1_human(display_long)|uniprotkb:C1orf48(gene name synonym)|uniprotkb:DC8(orf name)|uniprotkb:DC31(orf name)|uniprotkb:MIS14(orf name)|uniprotkb:NSL1(gene name)|psi-mi:NSL1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481244|imex:IM-26985-555 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245146.1|refseq:NP_001245147.1|refseq:NP_001245148.1|refseq:NP_001245149.1|refseq:XP_016880522.1|refseq:XP_016880523.1|refseq:XP_016880524.1|refseq:NP_076944.1|ensembl:ENSG00000167842(gene)|ensembl:ENST00000381165(transcript)|ensembl:ENST00000573759(transcript)|ensembl:ENST00000611091(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR008685(Mis12)|mint:Q9H081|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-5663220|refseq:XP_005256854.1 refseq:NP_056286.3|ensembl:ENSG00000117697(gene)|ensembl:ENST00000366977(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0005829"(cytosol)|go:"GO:0016607"(nuclear speck)|go:"GO:0051301"(cell division)|interpro:IPR013950(Kinetochore Mis14)|mint:Q96IY1|rcsb pdb:4NF9|rcsb pdb:5LSI|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-2500257|reactome:R-HSA-9648025|refseq:NP_001036014.1 - - comment:"author score: 138" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:1qNMwDq3AYOWnRnPa2u3yt7O4109606 rogid:w4K2MEHLfZvFECNhtDanXWF0LQk9606 rigid:Y9SPFQ7EkUZ80pEhDZa+coV+fRc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H081 uniprotkb:Q6P1K2 intact:EBI-1001205|uniprotkb:Q96N24|ensembl:ENSP00000370557|ensembl:ENSP00000461252|ensembl:ENSP00000484532 intact:EBI-713832|uniprotkb:Q5TCJ8|uniprotkb:Q5TCJ9|uniprotkb:Q5TCK3|uniprotkb:Q69YZ9|uniprotkb:Q6PHR4|uniprotkb:Q86VJ6|uniprotkb:Q8N4T6|uniprotkb:Q9UBQ3|uniprotkb:A8K0C5|intact:EBI-2554676|uniprotkb:Q5TCK0|ensembl:ENSP00000357260|uniprotkb:Q5TCK1|uniprotkb:Q6ZVE6 psi-mi:mis12_human(display_long)|uniprotkb:MIS12(gene name)|psi-mi:MIS12(display_short) psi-mi:pmf1_human(display_long)|uniprotkb:PMF1(gene name)|psi-mi:PMF1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481244|imex:IM-26985-555 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001245146.1|refseq:NP_001245147.1|refseq:NP_001245148.1|refseq:NP_001245149.1|refseq:XP_016880522.1|refseq:XP_016880523.1|refseq:XP_016880524.1|refseq:NP_076944.1|ensembl:ENSG00000167842(gene)|ensembl:ENST00000381165(transcript)|ensembl:ENST00000573759(transcript)|ensembl:ENST00000611091(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051382"(kinetochore assembly)|interpro:IPR008685(Mis12)|mint:Q9H081|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-68877|reactome:R-HSA-9648025|reactome:R-HSA-5663220|refseq:XP_005256854.1 ensembl:ENSG00000160783(gene)|ensembl:ENST00000368277(transcript)|go:"GO:0000444"(MIS12/MIND type complex)|go:"GO:0000776"(kinetochore)|go:"GO:0000818"(nuclear MIS12/MIND complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0051301"(cell division)|interpro:IPR007128(Nnf1)|mint:Q6P1K2|rcsb pdb:5LSJ|rcsb pdb:5LSK|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001186582.1|refseq:NP_001186583.1|refseq:NP_001186590.1|refseq:NP_001186592.1|refseq:NP_009152.2 - - comment:"author score: 146" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:1qNMwDq3AYOWnRnPa2u3yt7O4109606 rogid:76xPGmFgI3Pt1gsZMb3aD4hpPWM9606 rigid:Y9SPFQ7EkUZ80pEhDZa+coV+fRc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y483 uniprotkb:Q16576 intact:EBI-725816|uniprotkb:A6NGQ9|uniprotkb:Q9UES9|uniprotkb:Q9UP40|uniprotkb:A8K2Q3|uniprotkb:B1AKT5|intact:EBI-11028207|uniprotkb:Q96G26|uniprotkb:B1AKT6|ensembl:ENSP00000359321 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 psi-mi:mtf2_human(display_long)|uniprotkb:PCL2(gene name synonym)|uniprotkb:Metal-response element DNA-binding protein M96(gene name synonym)|uniprotkb:Metal regulatory transcription factor 2(gene name synonym)|uniprotkb:Polycomb-like protein 2(gene name synonym)|uniprotkb:MTF2(gene name)|psi-mi:MTF2(display_short) psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481400|imex:IM-26985-491 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001157863.1|refseq:NP_001157865.1|refseq:NP_031384.1|refseq:XP_011539318.1|refseq:XP_016856165.1|ensembl:ENSG00000143033(gene)|ensembl:ENST00000370298(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042015|mint:Q9Y483|rcsb pdb:5XFR|reactome:R-HSA-212300|interpro:IPR042014|refseq:NP_001157864.1 refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N - - comment:"author score: 36" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Im8E6U/OPb8AEir43AUUDlU6F2o9606 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rigid:7KdJ7GgIL/da92Jet16TLG3lP84 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y483 uniprotkb:Q96JN0 intact:EBI-725816|uniprotkb:A6NGQ9|uniprotkb:Q9UES9|uniprotkb:Q9UP40|uniprotkb:A8K2Q3|uniprotkb:B1AKT5|intact:EBI-11028207|uniprotkb:Q96G26|uniprotkb:B1AKT6|ensembl:ENSP00000359321 intact:EBI-746045|uniprotkb:Q9H945|uniprotkb:Q9Y457|ensembl:ENSP00000348298|ensembl:ENSP00000360138|ensembl:ENSP00000360144|ensembl:ENSP00000501560|ensembl:ENSP00000501639|ensembl:ENSP00000502633|intact:EBI-8833163|uniprotkb:D3DR47|uniprotkb:Q5VW16|uniprotkb:Q7Z723|uniprotkb:Q86T32|uniprotkb:Q86T33|uniprotkb:Q8N3L6|uniprotkb:Q8N655 psi-mi:mtf2_human(display_long)|uniprotkb:PCL2(gene name synonym)|uniprotkb:Metal-response element DNA-binding protein M96(gene name synonym)|uniprotkb:Metal regulatory transcription factor 2(gene name synonym)|uniprotkb:Polycomb-like protein 2(gene name synonym)|uniprotkb:MTF2(gene name)|psi-mi:MTF2(display_short) psi-mi:lcor_human(display_long)|uniprotkb:LCOR(gene name)|psi-mi:LCOR(display_short)|uniprotkb:C10orf12(gene name synonym)|uniprotkb:KIAA1795(gene name synonym)|uniprotkb:MLR2(gene name synonym)|uniprotkb:Mblk1-related protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481400|imex:IM-26985-491 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001157863.1|refseq:NP_001157865.1|refseq:NP_031384.1|refseq:XP_011539318.1|refseq:XP_016856165.1|ensembl:ENSG00000143033(gene)|ensembl:ENST00000370298(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042015|mint:Q9Y483|rcsb pdb:5XFR|reactome:R-HSA-212300|interpro:IPR042014|refseq:NP_001157864.1 ensembl:ENSG00000196233(gene)|ensembl:ENST00000356016(transcript)|ensembl:ENST00000371097(transcript)|ensembl:ENST00000371103(transcript)|ensembl:ENST00000675471(transcript)|ensembl:ENST00000675537(transcript)|ensembl:ENST00000675971(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|mint:Q96JN0|rcsb pdb:2COB|refseq:NP_001164236.1|refseq:NP_001164237.1|refseq:NP_115816.2|refseq:XP_016872275.1|refseq:XP_016872276.1|refseq:XP_016872277.1|refseq:NP_001333445.1 - - comment:"author score: 37" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Im8E6U/OPb8AEir43AUUDlU6F2o9606 rogid:cOnk6EDDff86yaG1uG+dxEQ1Z689606 rigid:7KdJ7GgIL/da92Jet16TLG3lP84 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y483 uniprotkb:Q09028 intact:EBI-725816|uniprotkb:A6NGQ9|uniprotkb:Q9UES9|uniprotkb:Q9UP40|uniprotkb:A8K2Q3|uniprotkb:B1AKT5|intact:EBI-11028207|uniprotkb:Q96G26|uniprotkb:B1AKT6|ensembl:ENSP00000359321 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 psi-mi:mtf2_human(display_long)|uniprotkb:PCL2(gene name synonym)|uniprotkb:Metal-response element DNA-binding protein M96(gene name synonym)|uniprotkb:Metal regulatory transcription factor 2(gene name synonym)|uniprotkb:Polycomb-like protein 2(gene name synonym)|uniprotkb:MTF2(gene name)|psi-mi:MTF2(display_short) psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481400|imex:IM-26985-491 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001157863.1|refseq:NP_001157865.1|refseq:NP_031384.1|refseq:XP_011539318.1|refseq:XP_016856165.1|ensembl:ENSG00000143033(gene)|ensembl:ENST00000370298(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042015|mint:Q9Y483|rcsb pdb:5XFR|reactome:R-HSA-212300|interpro:IPR042014|refseq:NP_001157864.1 ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N - - comment:"author score: 65" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Im8E6U/OPb8AEir43AUUDlU6F2o9606 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rigid:7KdJ7GgIL/da92Jet16TLG3lP84 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y483 uniprotkb:Q92800 intact:EBI-725816|uniprotkb:A6NGQ9|uniprotkb:Q9UES9|uniprotkb:Q9UP40|uniprotkb:A8K2Q3|uniprotkb:B1AKT5|intact:EBI-11028207|uniprotkb:Q96G26|uniprotkb:B1AKT6|ensembl:ENSP00000359321 intact:EBI-8830732|uniprotkb:B4E3R7|uniprotkb:O43287|uniprotkb:A6NCH6|uniprotkb:Q14459|uniprotkb:Q53XP3|uniprotkb:B4DSS2|uniprotkb:B4DIJ1|uniprotkb:B4DIZ7|ensembl:ENSP00000404658|ensembl:ENSP00000466924 psi-mi:mtf2_human(display_long)|uniprotkb:PCL2(gene name synonym)|uniprotkb:Metal-response element DNA-binding protein M96(gene name synonym)|uniprotkb:Metal regulatory transcription factor 2(gene name synonym)|uniprotkb:Polycomb-like protein 2(gene name synonym)|uniprotkb:MTF2(gene name)|psi-mi:MTF2(display_short) psi-mi:ezh1_human(display_long)|uniprotkb:ENX-2(gene name synonym)|uniprotkb:Enhancer of zeste homolog 1(gene name synonym)|uniprotkb:KIAA0388(gene name synonym)|uniprotkb:EZH1(gene name)|psi-mi:EZH1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481400|imex:IM-26985-491 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001157863.1|refseq:NP_001157865.1|refseq:NP_031384.1|refseq:XP_011539318.1|refseq:XP_016856165.1|ensembl:ENSG00000143033(gene)|ensembl:ENST00000370298(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042015|mint:Q9Y483|rcsb pdb:5XFR|reactome:R-HSA-212300|interpro:IPR042014|refseq:NP_001157864.1 refseq:NP_001308008.1|refseq:NP_001308010.1|refseq:NP_001308011.1|refseq:NP_001982.2|dip:DIP-58580N|ensembl:ENSG00000108799(gene)|ensembl:ENST00000428826(transcript)|ensembl:ENST00000592743(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0021766"(hippocampus development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0031507"(heterochromatin assembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR021654|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR032926|interpro:IPR041343|interpro:IPR041355|interpro:IPR044438|mint:Q92800|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP - - comment:"author score: 68" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Im8E6U/OPb8AEir43AUUDlU6F2o9606 rogid:qp3eqBCgiaoA6VSSyqpW1d9YKN49606 rigid:7KdJ7GgIL/da92Jet16TLG3lP84 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y483 uniprotkb:O75530 intact:EBI-725816|uniprotkb:A6NGQ9|uniprotkb:Q9UES9|uniprotkb:Q9UP40|uniprotkb:A8K2Q3|uniprotkb:B1AKT5|intact:EBI-11028207|uniprotkb:Q96G26|uniprotkb:B1AKT6|ensembl:ENSP00000359321 intact:EBI-923794|intact:EBI-2839778|intact:EBI-1177693|uniprotkb:A8K7V5|uniprotkb:Q6NTH2|uniprotkb:Q7LDA5|uniprotkb:Q7LDG8|uniprotkb:Q86VV2|uniprotkb:Q9UNY7|uniprotkb:O00149|ensembl:ENSP00000263360|ensembl:ENSP00000500834 psi-mi:mtf2_human(display_long)|uniprotkb:PCL2(gene name synonym)|uniprotkb:Metal-response element DNA-binding protein M96(gene name synonym)|uniprotkb:Metal regulatory transcription factor 2(gene name synonym)|uniprotkb:Polycomb-like protein 2(gene name synonym)|uniprotkb:MTF2(gene name)|psi-mi:MTF2(display_short) psi-mi:eed_human(display_long)|uniprotkb:EED(gene name)|psi-mi:EED(display_short)|uniprotkb:WD protein associating with integrin cytoplasmic tails 1(gene name synonym)|uniprotkb:Embryonic ectoderm development protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481400|imex:IM-26985-491 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001157863.1|refseq:NP_001157865.1|refseq:NP_031384.1|refseq:XP_011539318.1|refseq:XP_016856165.1|ensembl:ENSG00000143033(gene)|ensembl:ENST00000370298(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042015|mint:Q9Y483|rcsb pdb:5XFR|reactome:R-HSA-212300|interpro:IPR042014|refseq:NP_001157864.1 refseq:NP_003788.2|refseq:NP_001294936.1|dip:DIP-36673N|ensembl:ENSG00000074266(gene)|ensembl:ENST00000263360(transcript)|ensembl:ENST00000672825(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0021510"(spinal cord development)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:O75530|rcsb pdb:3IIW|rcsb pdb:3IIY|rcsb pdb:3IJ0|rcsb pdb:3IJ1|rcsb pdb:3IJC|rcsb pdb:3JPX|rcsb pdb:3JZG|rcsb pdb:3JZH|rcsb pdb:3JZN|rcsb pdb:3K26|rcsb pdb:3K27|rcsb pdb:4W2R|rcsb pdb:4X3E|rcsb pdb:5GSA|rcsb pdb:5H13|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5K0M|rcsb pdb:5LS6|rcsb pdb:5TTW|rcsb pdb:5U5H|rcsb pdb:5U5K|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5U69|rcsb pdb:5U6D|rcsb pdb:5U8A|rcsb pdb:5U8F|rcsb pdb:5WG6|rcsb pdb:5WP3|rcsb pdb:5WUK|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6SFB|rcsb pdb:6SFC|rcsb pdb:6U4Y|rcsb pdb:6V3X|rcsb pdb:6V3Y|rcsb pdb:6W7F|rcsb pdb:6W7G|rcsb pdb:6WKR|rcsb pdb:6YVI|rcsb pdb:6YVJ|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7KXT|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421 - - comment:"author score: 154" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Im8E6U/OPb8AEir43AUUDlU6F2o9606 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA9606 rigid:7KdJ7GgIL/da92Jet16TLG3lP84 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y483 uniprotkb:Q15910 intact:EBI-725816|uniprotkb:A6NGQ9|uniprotkb:Q9UES9|uniprotkb:Q9UP40|uniprotkb:A8K2Q3|uniprotkb:B1AKT5|intact:EBI-11028207|uniprotkb:Q96G26|uniprotkb:B1AKT6|ensembl:ENSP00000359321 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 psi-mi:mtf2_human(display_long)|uniprotkb:PCL2(gene name synonym)|uniprotkb:Metal-response element DNA-binding protein M96(gene name synonym)|uniprotkb:Metal regulatory transcription factor 2(gene name synonym)|uniprotkb:Polycomb-like protein 2(gene name synonym)|uniprotkb:MTF2(gene name)|psi-mi:MTF2(display_short) psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481400|imex:IM-26985-491 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001157863.1|refseq:NP_001157865.1|refseq:NP_031384.1|refseq:XP_011539318.1|refseq:XP_016856165.1|ensembl:ENSG00000143033(gene)|ensembl:ENST00000370298(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042015|mint:Q9Y483|rcsb pdb:5XFR|reactome:R-HSA-212300|interpro:IPR042014|refseq:NP_001157864.1 refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N - - comment:"author score: 160" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Im8E6U/OPb8AEir43AUUDlU6F2o9606 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 rigid:7KdJ7GgIL/da92Jet16TLG3lP84 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y483 uniprotkb:Q15022 intact:EBI-725816|uniprotkb:A6NGQ9|uniprotkb:Q9UES9|uniprotkb:Q9UP40|uniprotkb:A8K2Q3|uniprotkb:B1AKT5|intact:EBI-11028207|uniprotkb:Q96G26|uniprotkb:B1AKT6|ensembl:ENSP00000359321 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 psi-mi:mtf2_human(display_long)|uniprotkb:PCL2(gene name synonym)|uniprotkb:Metal-response element DNA-binding protein M96(gene name synonym)|uniprotkb:Metal regulatory transcription factor 2(gene name synonym)|uniprotkb:Polycomb-like protein 2(gene name synonym)|uniprotkb:MTF2(gene name)|psi-mi:MTF2(display_short) psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481400|imex:IM-26985-491 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001157863.1|refseq:NP_001157865.1|refseq:NP_031384.1|refseq:XP_011539318.1|refseq:XP_016856165.1|ensembl:ENSG00000143033(gene)|ensembl:ENST00000370298(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR040477|interpro:IPR042015|mint:Q9Y483|rcsb pdb:5XFR|reactome:R-HSA-212300|interpro:IPR042014|refseq:NP_001157864.1 dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421 - - comment:"author score: 165" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Im8E6U/OPb8AEir43AUUDlU6F2o9606 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 rigid:7KdJ7GgIL/da92Jet16TLG3lP84 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16352 uniprotkb:P55209 intact:EBI-366258|uniprotkb:Q9BRC5|uniprotkb:B1AQK0|ensembl:ENSP00000358865 intact:EBI-356392|ensembl:ENSP00000376947|ensembl:ENSP00000477538|uniprotkb:B3KV44|uniprotkb:B3KNT8 psi-mi:ainx_human(display_long)|uniprotkb:INA(gene name)|psi-mi:INA(display_short)|uniprotkb:66 kDa neurofilament protein(gene name synonym)|uniprotkb:Neurofilament 5(gene name synonym)|uniprotkb:NEF5(gene name synonym) psi-mi:np1l1_human(display_long)|uniprotkb:NAP1L1(gene name)|psi-mi:NAP1L1(display_short)|uniprotkb:NRP(gene name synonym)|uniprotkb:NAP-1-related protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25481427|imex:IM-26985-185 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116116.1|ensembl:ENSG00000148798(gene)|ensembl:ENST00000369849(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005615"(extracellular space)|go:"GO:0005883"(neurofilament)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030154"(cell differentiation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098973"(structural constituent of postsynaptic actin cytoskeleton)|go:"GO:0099184"(structural constituent of postsynaptic intermediate filament cytoskeleton)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR006821(Intermediate filament, DNA-binding region)|interpro:IPR018039|interpro:IPR027703|interpro:IPR039008|mint:Q16352 ensembl:ENSG00000187109(gene)|ensembl:ENST00000393263(transcript)|ensembl:ENST00000618691(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0042393"(histone binding)|go:"GO:0042470"(melanosome)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:P55209|rcsb pdb:7BP5|refseq:NP_004528.1|refseq:NP_631946.1|refseq:NP_001294853.1|refseq:XP_011536695.1|refseq:NP_001317160.1|refseq:NP_001317161.1|refseq:XP_016874827.1 - comment:"author score: 12" - figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:HXC2d0wajSa0s9r7b4qtpqi3g+s9606 rogid:PtjzXGuxpQqrIEt5cbwzsbUoze89606 rigid:+yYaHeNOjdEmsCmy3/Efq/fTX/k false - tandem tag:n-n - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P55209 uniprotkb:Q99733 intact:EBI-356392|ensembl:ENSP00000376947|ensembl:ENSP00000477538|uniprotkb:B3KV44|uniprotkb:B3KNT8 intact:EBI-2255116|uniprotkb:B2R6J4|uniprotkb:F5HFY4|ensembl:ENSP00000369915|ensembl:ENSP00000483728 psi-mi:np1l1_human(display_long)|uniprotkb:NAP1L1(gene name)|psi-mi:NAP1L1(display_short)|uniprotkb:NRP(gene name synonym)|uniprotkb:NAP-1-related protein(gene name synonym) psi-mi:np1l4_human(display_long)|uniprotkb:NAP1L4(gene name)|psi-mi:NAP1L4(display_short)|uniprotkb:NAP2(gene name synonym)|uniprotkb:Nucleosome assembly protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25481436|imex:IM-26985-111 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000187109(gene)|ensembl:ENST00000393263(transcript)|ensembl:ENST00000618691(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0042393"(histone binding)|go:"GO:0042470"(melanosome)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:P55209|rcsb pdb:7BP5|refseq:NP_004528.1|refseq:NP_631946.1|refseq:NP_001294853.1|refseq:XP_011536695.1|refseq:NP_001317160.1|refseq:NP_001317161.1|refseq:XP_016874827.1 refseq:NP_005960.1|ensembl:ENSG00000205531(gene)|ensembl:ENSG00000273562(gene)|ensembl:ENST00000380542(transcript)|ensembl:ENST00000619695(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031491"(nucleosome binding)|go:"GO:0042393"(histone binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q99733 - comment:"author score: 115" - figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:PtjzXGuxpQqrIEt5cbwzsbUoze89606 rogid:tES8IJDlW4JONR/pdC8dq49I/7Y9606 rigid:GRQpdwsZNuvdy/33QwhhdD1oBvc false - tandem tag:n-n - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96DG6 uniprotkb:P06899 intact:EBI-1044268|uniprotkb:Q8TED6|uniprotkb:D3DTC7|ensembl:ENSP00000296658 intact:EBI-6150252|uniprotkb:B2R4J4|uniprotkb:O60816|ensembl:ENSP00000342886|ensembl:ENSP00000476136 psi-mi:cmbl_human(display_long)|uniprotkb:CMBL(gene name)|psi-mi:CMBL(display_short) psi-mi:h2b1j_human(display_long)|uniprotkb:H2BC11(gene name)|psi-mi:H2BC11(display_short)|uniprotkb:H2BFR(gene name synonym)|uniprotkb:HIST1H2BJ(gene name synonym)|uniprotkb:Histone H2B.1(gene name synonym)|uniprotkb:Histone H2B.r(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481445|imex:IM-26985-113 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_620164.1|ensembl:ENSG00000164237(gene)|ensembl:ENST00000296658(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002925(Dienelactone hydrolase)|interpro:IPR029058|interpro:IPR042946|mint:Q96DG6|reactome:R-HSA-211945|refseq:XP_016864523.1|refseq:XP_016864524.1 refseq:NP_066402.2|dip:DIP-421N|ensembl:ENSG00000124635(gene)|ensembl:ENST00000339812(transcript)|ensembl:ENST00000607124(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P06899|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WAA|rcsb pdb:3WTP|rcsb pdb:4CAY|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5FUG|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5VEY|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6JXD|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6YOV|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7K5X|rcsb pdb:3WA9|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - comment:"author score: 25" comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nIOgS/jTgYbRXndPjCCMtqb0cHU9606 rogid:74GQlSjGG1Ez6Uog74VXPLryKBc9606 rigid:0P+C/xBUjFYfJBNpLJUmeJtFiVw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96DG6 uniprotkb:Q68D91 intact:EBI-1044268|uniprotkb:Q8TED6|uniprotkb:D3DTC7|ensembl:ENSP00000296658 intact:EBI-21018038|ensembl:ENSP00000314776|uniprotkb:D6RJI1|uniprotkb:Q8IY16|uniprotkb:Q8N8D8 psi-mi:cmbl_human(display_long)|uniprotkb:CMBL(gene name)|psi-mi:CMBL(display_short) psi-mi:mblc2_human(display_long)|uniprotkb:MBLAC2(gene name)|psi-mi:MBLAC2(display_short)|uniprotkb:Beta-lactamase MBLAC2(gene name synonym)|uniprotkb:Metallo-beta-lactamase domain-containing protein 2(gene name synonym)|uniprotkb:Palmitoyl-coenzyme A thioesterase MBLAC2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481445|imex:IM-26985-113 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_620164.1|ensembl:ENSG00000164237(gene)|ensembl:ENST00000296658(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002925(Dienelactone hydrolase)|interpro:IPR029058|interpro:IPR042946|mint:Q96DG6|reactome:R-HSA-211945|refseq:XP_016864523.1|refseq:XP_016864524.1 ensembl:ENSG00000176055(gene)|ensembl:ENST00000316610(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0016290"(palmitoyl-CoA hydrolase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001279(Beta-lactamase-like)|interpro:IPR036866|mint:Q68D91|refseq:NP_981951.1 - comment:"author score: 25" comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nIOgS/jTgYbRXndPjCCMtqb0cHU9606 rogid:hVVlxJgyWR3x03vg/EwJ1ktKUcM9606 rigid:0P+C/xBUjFYfJBNpLJUmeJtFiVw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96DG6 uniprotkb:Q96RQ3 intact:EBI-1044268|uniprotkb:Q8TED6|uniprotkb:D3DTC7|ensembl:ENSP00000296658 intact:EBI-2211703|uniprotkb:Q59ES4|uniprotkb:Q9H959|uniprotkb:Q9NS97|ensembl:ENSP00000265594 psi-mi:cmbl_human(display_long)|uniprotkb:CMBL(gene name)|psi-mi:CMBL(display_short) psi-mi:mcca_human(display_long)|uniprotkb:MCCC1(gene name)|psi-mi:MCCC1(display_short)|uniprotkb:MCCA(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase 1(gene name synonym)|uniprotkb:"3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha"(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase biotin-containing subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481445|imex:IM-26985-113 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_620164.1|ensembl:ENSG00000164237(gene)|ensembl:ENST00000296658(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002925(Dienelactone hydrolase)|interpro:IPR029058|interpro:IPR042946|mint:Q96DG6|reactome:R-HSA-211945|refseq:XP_016864523.1|refseq:XP_016864524.1 refseq:NP_064551.3|refseq:NP_001280202.1|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR016185(PreATP-grasp-like fold)|mint:Q96RQ3|rcsb pdb:2EJM|reactome:R-HSA-196780|reactome:R-HSA-3371599|reactome:R-HSA-70895|ensembl:ENSG00000078070(gene)|ensembl:ENST00000265594(transcript)|go:"GO:0002169"(3-methylcrotonyl-CoA carboxylase complex, mitochondrial)|go:"GO:0004075"(biotin carboxylase activity)|go:"GO:0004485"(methylcrotonoyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0006768"(biotin metabolic process)|go:"GO:0009374"(biotin binding)|go:"GO:0016421"(CoA carboxylase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:1905202"(methylcrotonoyl-CoA carboxylase complex)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001882(Biotin-binding site)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding) - comment:"author score: 25" comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nIOgS/jTgYbRXndPjCCMtqb0cHU9606 rogid:obze7v7i2yTIIcJjd7laIriNFg89606 rigid:0P+C/xBUjFYfJBNpLJUmeJtFiVw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96DG6 uniprotkb:Q9HCC0 intact:EBI-1044268|uniprotkb:Q8TED6|uniprotkb:D3DTC7|ensembl:ENSP00000296658 intact:EBI-2211296|uniprotkb:A6NIY9|uniprotkb:Q96C27|uniprotkb:Q9Y4L7|ensembl:ENSP00000343657 psi-mi:cmbl_human(display_long)|uniprotkb:CMBL(gene name)|psi-mi:CMBL(display_short) psi-mi:mccb_human(display_long)|uniprotkb:MCCC2(gene name)|psi-mi:MCCC2(display_short)|uniprotkb:MCCB(gene name synonym)|uniprotkb:"3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta"(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481445|imex:IM-26985-113 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_620164.1|ensembl:ENSG00000164237(gene)|ensembl:ENST00000296658(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002925(Dienelactone hydrolase)|interpro:IPR029058|interpro:IPR042946|mint:Q96DG6|reactome:R-HSA-211945|refseq:XP_016864523.1|refseq:XP_016864524.1 refseq:NP_071415.1|refseq:XP_005248624.1|ensembl:ENSG00000131844(gene)|ensembl:ENST00000340941(transcript)|go:"GO:0002169"(3-methylcrotonyl-CoA carboxylase complex, mitochondrial)|go:"GO:0004485"(methylcrotonoyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:1905202"(methylcrotonoyl-CoA carboxylase complex)|interpro:IPR011762(Acetyl-coenzyme A carboxyltransferase, N-terminal)|interpro:IPR011763(Acetyl-coenzyme A carboxyltransferase, C-terminal)|interpro:IPR029045|interpro:IPR034733|mint:Q9HCC0|reactome:R-HSA-196780|reactome:R-HSA-3371599|reactome:R-HSA-70895 - comment:"author score: 25" comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nIOgS/jTgYbRXndPjCCMtqb0cHU9606 rogid:5NkqDKqdX1wHsbqXW7v5+/Gld109606 rigid:0P+C/xBUjFYfJBNpLJUmeJtFiVw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96DG6 uniprotkb:Q70IA6 intact:EBI-1044268|uniprotkb:Q8TED6|uniprotkb:D3DTC7|ensembl:ENSP00000296658 intact:EBI-2558739|uniprotkb:Q96M67|uniprotkb:B4DKP3 psi-mi:cmbl_human(display_long)|uniprotkb:CMBL(gene name)|psi-mi:CMBL(display_short) psi-mi:mob2_human(display_long)|uniprotkb:MOB2(gene name)|psi-mi:MOB2(display_short)|uniprotkb:HCCA2(gene name synonym)|uniprotkb:Mob2 homolog(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481445|imex:IM-26985-113 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_620164.1|ensembl:ENSG00000164237(gene)|ensembl:ENST00000296658(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002925(Dienelactone hydrolase)|interpro:IPR029058|interpro:IPR042946|mint:Q96DG6|reactome:R-HSA-211945|refseq:XP_016864523.1|refseq:XP_016864524.1 refseq:NP_001165694.1|refseq:NP_443731.2|interpro:IPR005301(Mob1/phocein)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR036703|mint:Q70IA6 - comment:"author score: 25" comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nIOgS/jTgYbRXndPjCCMtqb0cHU9606 rogid:bPhfXMdT6x7s05Ufn4VZrMRgcL89606 rigid:0P+C/xBUjFYfJBNpLJUmeJtFiVw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96DG6 uniprotkb:Q9Y3C1 intact:EBI-1044268|uniprotkb:Q8TED6|uniprotkb:D3DTC7|ensembl:ENSP00000296658 intact:EBI-5453434|uniprotkb:Q6IAI6|uniprotkb:Q8IXL5|uniprotkb:Q6PIM0|uniprotkb:B4DV13|uniprotkb:D6RGD3|uniprotkb:Q05D05|ensembl:ENSP00000480832 psi-mi:cmbl_human(display_long)|uniprotkb:CMBL(gene name)|psi-mi:CMBL(display_short) psi-mi:nop16_human(display_long)|uniprotkb:NOP16(gene name)|psi-mi:NOP16(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 3(gene name synonym)|uniprotkb:CGI-117(orf name)|uniprotkb:HSPC111(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481445|imex:IM-26985-113 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_620164.1|ensembl:ENSG00000164237(gene)|ensembl:ENST00000296658(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002925(Dienelactone hydrolase)|interpro:IPR029058|interpro:IPR042946|mint:Q96DG6|reactome:R-HSA-211945|refseq:XP_016864523.1|refseq:XP_016864524.1 refseq:NP_057475.2|refseq:NP_001304904.1|refseq:NP_001243468.2|refseq:NP_001278234.1|refseq:NP_001278236.1|refseq:NP_001278237.1|refseq:NP_001243469.2|ensembl:ENSG00000048162(gene)|ensembl:ENST00000614830(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019002|mint:Q9Y3C1 - comment:"author score: 25" comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nIOgS/jTgYbRXndPjCCMtqb0cHU9606 rogid:HdIqgMgye+B+sa3XiPdqvLXbcR89606 rigid:0P+C/xBUjFYfJBNpLJUmeJtFiVw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96DG6 uniprotkb:P55209 intact:EBI-1044268|uniprotkb:Q8TED6|uniprotkb:D3DTC7|ensembl:ENSP00000296658 intact:EBI-356392|ensembl:ENSP00000376947|ensembl:ENSP00000477538|uniprotkb:B3KV44|uniprotkb:B3KNT8 psi-mi:cmbl_human(display_long)|uniprotkb:CMBL(gene name)|psi-mi:CMBL(display_short) psi-mi:np1l1_human(display_long)|uniprotkb:NAP1L1(gene name)|psi-mi:NAP1L1(display_short)|uniprotkb:NRP(gene name synonym)|uniprotkb:NAP-1-related protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481445|imex:IM-26985-113 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_620164.1|ensembl:ENSG00000164237(gene)|ensembl:ENST00000296658(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002925(Dienelactone hydrolase)|interpro:IPR029058|interpro:IPR042946|mint:Q96DG6|reactome:R-HSA-211945|refseq:XP_016864523.1|refseq:XP_016864524.1 ensembl:ENSG00000187109(gene)|ensembl:ENST00000393263(transcript)|ensembl:ENST00000618691(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0042393"(histone binding)|go:"GO:0042470"(melanosome)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:P55209|rcsb pdb:7BP5|refseq:NP_004528.1|refseq:NP_631946.1|refseq:NP_001294853.1|refseq:XP_011536695.1|refseq:NP_001317160.1|refseq:NP_001317161.1|refseq:XP_016874827.1 - comment:"author score: 25" comment:"author score: 66" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nIOgS/jTgYbRXndPjCCMtqb0cHU9606 rogid:PtjzXGuxpQqrIEt5cbwzsbUoze89606 rigid:0P+C/xBUjFYfJBNpLJUmeJtFiVw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96DG6 uniprotkb:Q99733 intact:EBI-1044268|uniprotkb:Q8TED6|uniprotkb:D3DTC7|ensembl:ENSP00000296658 intact:EBI-2255116|uniprotkb:B2R6J4|uniprotkb:F5HFY4|ensembl:ENSP00000369915|ensembl:ENSP00000483728 psi-mi:cmbl_human(display_long)|uniprotkb:CMBL(gene name)|psi-mi:CMBL(display_short) psi-mi:np1l4_human(display_long)|uniprotkb:NAP1L4(gene name)|psi-mi:NAP1L4(display_short)|uniprotkb:NAP2(gene name synonym)|uniprotkb:Nucleosome assembly protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481445|imex:IM-26985-113 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_620164.1|ensembl:ENSG00000164237(gene)|ensembl:ENST00000296658(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002925(Dienelactone hydrolase)|interpro:IPR029058|interpro:IPR042946|mint:Q96DG6|reactome:R-HSA-211945|refseq:XP_016864523.1|refseq:XP_016864524.1 refseq:NP_005960.1|ensembl:ENSG00000205531(gene)|ensembl:ENSG00000273562(gene)|ensembl:ENST00000380542(transcript)|ensembl:ENST00000619695(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0031491"(nucleosome binding)|go:"GO:0042393"(histone binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q99733 - comment:"author score: 25" comment:"author score: 84" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nIOgS/jTgYbRXndPjCCMtqb0cHU9606 rogid:tES8IJDlW4JONR/pdC8dq49I/7Y9606 rigid:0P+C/xBUjFYfJBNpLJUmeJtFiVw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96DG6 uniprotkb:Q96NT1 intact:EBI-1044268|uniprotkb:Q8TED6|uniprotkb:D3DTC7|ensembl:ENSP00000296658 intact:EBI-713627|ensembl:ENSP00000320488|intact:EBI-5774422 psi-mi:cmbl_human(display_long)|uniprotkb:CMBL(gene name)|psi-mi:CMBL(display_short) psi-mi:np1l5_human(display_long)|uniprotkb:NAP1L5(gene name)|psi-mi:NAP1L5(display_short)|uniprotkb:DRLM(gene name synonym)|uniprotkb:Down-regulated in liver malignancy(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481445|imex:IM-26985-113 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_620164.1|ensembl:ENSG00000164237(gene)|ensembl:ENST00000296658(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002925(Dienelactone hydrolase)|interpro:IPR029058|interpro:IPR042946|mint:Q96DG6|reactome:R-HSA-211945|refseq:XP_016864523.1|refseq:XP_016864524.1 ensembl:ENSG00000177432(gene)|ensembl:ENST00000323061(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0042393"(histone binding)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q96NT1|refseq:NP_715638.1 - comment:"author score: 25" - figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nIOgS/jTgYbRXndPjCCMtqb0cHU9606 rogid:VI8GuGWxjsUbTX2Yhi+57eb/hj49606 rigid:0P+C/xBUjFYfJBNpLJUmeJtFiVw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96DG6 uniprotkb:Q9NPF4 intact:EBI-1044268|uniprotkb:Q8TED6|uniprotkb:D3DTC7|ensembl:ENSP00000296658 intact:EBI-1056510|uniprotkb:Q6IAC3|ensembl:ENSP00000206542 psi-mi:cmbl_human(display_long)|uniprotkb:CMBL(gene name)|psi-mi:CMBL(display_short) psi-mi:osgep_human(display_long)|uniprotkb:"t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEP"(gene name synonym)|uniprotkb:OSGEP(gene name)|psi-mi:OSGEP(display_short)|uniprotkb:GCPL1(gene name synonym)|uniprotkb:O-sialoglycoprotein endopeptidase(gene name synonym)|uniprotkb:tRNA threonylcarbamoyladenosine biosynthesis protein OSGEP(gene name synonym)|uniprotkb:N6-L-threonylcarbamoyladenine synthase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481445|imex:IM-26985-113 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_620164.1|ensembl:ENSG00000164237(gene)|ensembl:ENST00000296658(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002925(Dienelactone hydrolase)|interpro:IPR029058|interpro:IPR042946|mint:Q96DG6|reactome:R-HSA-211945|refseq:XP_016864523.1|refseq:XP_016864524.1 refseq:NP_060277.1|ensembl:ENSG00000092094(gene)|ensembl:ENST00000206542(transcript)|go:"GO:0000408"(EKC/KEOPS complex)|go:"GO:0002949"(tRNA threonylcarbamoyladenosine modification)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0046872"(metal ion binding)|go:"GO:0061711"("N(6)-L-threonylcarbamoyladenine synthase activity")|interpro:IPR000905(Peptidase M22, glycoprotease)|interpro:IPR017860|interpro:IPR017861|interpro:IPR034680|interpro:IPR043129|mint:Q9NPF4|rcsb pdb:6GWJ|reactome:R-HSA-6782315 - comment:"author score: 25" comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nIOgS/jTgYbRXndPjCCMtqb0cHU9606 rogid:gdWaUekKJ7WFXfPlaleW9Dpmsi89606 rigid:0P+C/xBUjFYfJBNpLJUmeJtFiVw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96DG6 uniprotkb:Q16769 intact:EBI-1044268|uniprotkb:Q8TED6|uniprotkb:D3DTC7|ensembl:ENSP00000296658 intact:EBI-2856807|uniprotkb:Q3KRG6|uniprotkb:Q16770|uniprotkb:Q53TR4|ensembl:ENSP00000344829 psi-mi:cmbl_human(display_long)|uniprotkb:CMBL(gene name)|psi-mi:CMBL(display_short) psi-mi:qpct_human(display_long)|uniprotkb:QPCT(gene name)|psi-mi:QPCT(display_short)|uniprotkb:Glutaminyl cyclase(gene name synonym)|uniprotkb:Glutaminyl-tRNA cyclotransferase(gene name synonym)|uniprotkb:Glutamyl cyclase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481445|imex:IM-26985-113 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_620164.1|ensembl:ENSG00000164237(gene)|ensembl:ENST00000296658(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002925(Dienelactone hydrolase)|interpro:IPR029058|interpro:IPR042946|mint:Q96DG6|reactome:R-HSA-211945|refseq:XP_016864523.1|refseq:XP_016864524.1 refseq:NP_036545.1|ensembl:ENSG00000115828(gene)|ensembl:ENST00000338415(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016603"(glutaminyl-peptide cyclotransferase activity)|go:"GO:0017186"(peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase)|go:"GO:0035580"(specific granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR007484(Peptidase M28)|interpro:IPR037457|interpro:IPR040234|mint:Q16769|rcsb pdb:1MOI|rcsb pdb:2AFM|rcsb pdb:2AFO|rcsb pdb:2AFS|rcsb pdb:2AFU|rcsb pdb:2AFW|rcsb pdb:2AFX|rcsb pdb:2AFZ|rcsb pdb:2ZED|rcsb pdb:2ZEE|rcsb pdb:2ZEF|rcsb pdb:2ZEG|rcsb pdb:2ZEH|rcsb pdb:2ZEL|rcsb pdb:2ZEM|rcsb pdb:2ZEN|rcsb pdb:2ZEO|rcsb pdb:2ZEP|rcsb pdb:3PBB|rcsb pdb:3PBE|rcsb pdb:3SI0|rcsb pdb:4YU9|rcsb pdb:4YWY|rcsb pdb:6YI1|rcsb pdb:6YJY|rcsb pdb:7COZ|rcsb pdb:7CP0|reactome:R-HSA-6798695|rcsb pdb:6GBX - comment:"author score: 25" comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nIOgS/jTgYbRXndPjCCMtqb0cHU9606 rogid:P77dag9F4CgK4eLQHdFlYbz4Kxg9606 rigid:0P+C/xBUjFYfJBNpLJUmeJtFiVw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96DG6 uniprotkb:Q02878 intact:EBI-1044268|uniprotkb:Q8TED6|uniprotkb:D3DTC7|ensembl:ENSP00000296658 intact:EBI-359655|uniprotkb:Q2M3Q3|uniprotkb:Q8WW97|ensembl:ENSP00000202773|ensembl:ENSP00000403172 psi-mi:cmbl_human(display_long)|uniprotkb:CMBL(gene name)|psi-mi:CMBL(display_short) psi-mi:rl6_human(display_long)|uniprotkb:RPL6(gene name)|psi-mi:RPL6(display_short)|uniprotkb:TXREB1(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 107(gene name synonym)|uniprotkb:Neoplasm-related protein C140(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481445|imex:IM-26985-113 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_620164.1|ensembl:ENSG00000164237(gene)|ensembl:ENST00000296658(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002925(Dienelactone hydrolase)|interpro:IPR029058|interpro:IPR042946|mint:Q96DG6|reactome:R-HSA-211945|refseq:XP_016864523.1|refseq:XP_016864524.1 refseq:NP_000961.2|refseq:NP_001019833.1|ensembl:ENSG00000089009(gene)|ensembl:ENST00000202773(transcript)|ensembl:ENST00000424576(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR000915(Ribosomal protein L6E)|interpro:IPR005568(Ribosomal protein L6, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041997|mint:Q02878|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001307066.1|refseq:NP_001307067.1|refseq:NP_001307068.1|refseq:NP_001307069.1|refseq:NP_001307070.1|refseq:XP_016875270.1|refseq:XP_016875271.1|dip:DIP-27547N - comment:"author score: 25" comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nIOgS/jTgYbRXndPjCCMtqb0cHU9606 rogid:Y7fx3ToInzucV2QmI8KLSdHxai09606 rigid:0P+C/xBUjFYfJBNpLJUmeJtFiVw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96DG6 uniprotkb:Q9Y2H1 intact:EBI-1044268|uniprotkb:Q8TED6|uniprotkb:D3DTC7|ensembl:ENSP00000296658 intact:EBI-991501|uniprotkb:Q8TBX7|uniprotkb:A8K4U0|uniprotkb:B4E3J8|ensembl:ENSP00000373684 psi-mi:cmbl_human(display_long)|uniprotkb:CMBL(gene name)|psi-mi:CMBL(display_short) psi-mi:st38l_human(display_long)|uniprotkb:NDR2 protein kinase(gene name synonym)|uniprotkb:Nuclear Dbf2-related kinase 2(gene name synonym)|uniprotkb:STK38L(gene name)|psi-mi:STK38L(display_short)|uniprotkb:KIAA0965(gene name synonym)|uniprotkb:NDR2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481445|imex:IM-26985-113 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_620164.1|ensembl:ENSG00000164237(gene)|ensembl:ENST00000296658(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002925(Dienelactone hydrolase)|interpro:IPR029058|interpro:IPR042946|mint:Q96DG6|reactome:R-HSA-211945|refseq:XP_016864523.1|refseq:XP_016864524.1 refseq:XP_006719121.1|ensembl:ENSG00000211455(gene)|ensembl:ENST00000389032(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003779"(actin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0051128"(regulation of cellular component organization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0005524"(ATP binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|mint:Q9Y2H1|rcsb pdb:5XQZ|refseq:NP_055815.1|refseq:XP_011518915.1|refseq:XP_016874525.1 - comment:"author score: 25" comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nIOgS/jTgYbRXndPjCCMtqb0cHU9606 rogid:lKXWdkeLMD/YCxa1oQz9k0aoW3I9606 rigid:0P+C/xBUjFYfJBNpLJUmeJtFiVw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96DG6 uniprotkb:Q13595 intact:EBI-1044268|uniprotkb:Q8TED6|uniprotkb:D3DTC7|ensembl:ENSP00000296658 intact:EBI-2685506|uniprotkb:B4DUA9|uniprotkb:B4DQI6|uniprotkb:E9PD75|ensembl:ENSP00000297071 psi-mi:cmbl_human(display_long)|uniprotkb:CMBL(gene name)|psi-mi:CMBL(display_short) psi-mi:tra2a_human(display_long)|uniprotkb:Transformer-2 protein homolog A(gene name synonym)|uniprotkb:TRA2A(gene name)|psi-mi:TRA2A(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481445|imex:IM-26985-113 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_620164.1|ensembl:ENSG00000164237(gene)|ensembl:ENST00000296658(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002925(Dienelactone hydrolase)|interpro:IPR029058|interpro:IPR042946|mint:Q96DG6|reactome:R-HSA-211945|refseq:XP_016864523.1|refseq:XP_016864524.1 refseq:NP_001269686.1|refseq:NP_001269687.1|refseq:NP_001269688.1|refseq:XP_005249782.1|refseq:NP_037425.1|refseq:XP_016867578.1|refseq:XP_016867579.1|ensembl:ENSG00000164548(gene)|ensembl:ENST00000297071(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:Q13595 - comment:"author score: 25" comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nIOgS/jTgYbRXndPjCCMtqb0cHU9606 rogid:JvcdzipB7mCy8eV3z8TaVjucLLM9606 rigid:0P+C/xBUjFYfJBNpLJUmeJtFiVw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96DG6 uniprotkb:Q9UJ04 intact:EBI-1044268|uniprotkb:Q8TED6|uniprotkb:D3DTC7|ensembl:ENSP00000296658 intact:EBI-308511|ensembl:ENSP00000410943|uniprotkb:O94828|uniprotkb:Q96GW8|uniprotkb:B4DYQ2 psi-mi:cmbl_human(display_long)|uniprotkb:CMBL(gene name)|psi-mi:CMBL(display_short) psi-mi:tsyl4_human(display_long)|uniprotkb:TSPYL4(gene name)|psi-mi:TSPYL4(display_short)|uniprotkb:KIAA0721(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481445|imex:IM-26985-113 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_620164.1|ensembl:ENSG00000164237(gene)|ensembl:ENST00000296658(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002925(Dienelactone hydrolase)|interpro:IPR029058|interpro:IPR042946|mint:Q96DG6|reactome:R-HSA-211945|refseq:XP_016864523.1|refseq:XP_016864524.1 ensembl:ENSG00000187189(gene)|ensembl:ENST00000420283(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0042393"(histone binding)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q9UJ04|refseq:NP_067680.3 - comment:"author score: 25" comment:"author score: 27" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nIOgS/jTgYbRXndPjCCMtqb0cHU9606 rogid:xcAq3OJVo+H+zV8Tq/wwdwthb3M9606 rigid:0P+C/xBUjFYfJBNpLJUmeJtFiVw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N5Y2 uniprotkb:P68363 intact:EBI-2560796|ensembl:ENSP00000312244|uniprotkb:Q9Y5Z8|uniprotkb:Q9UG70|uniprotkb:B7Z227|uniprotkb:B4DUV8|uniprotkb:A6NCU2|uniprotkb:A6NHW8|uniprotkb:A8K165 intact:EBI-487083|intact:EBI-1384226|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:Q27I68|ensembl:ENSP00000336799|uniprotkb:Q8WU19 psi-mi:ms3l1_human(display_long)|uniprotkb:MSL3(gene name)|psi-mi:MSL3(display_short)|uniprotkb:MSL3L1(gene name synonym)|uniprotkb:Male-specific lethal-3 protein-like 1(gene name synonym)|uniprotkb:Male-specific lethal-3 homolog 1(gene name synonym) psi-mi:tba1b_human(display_long)|uniprotkb:TUBA1B(gene name)|psi-mi:TUBA1B(display_short)|uniprotkb:Tubulin alpha-ubiquitous chain(gene name synonym)|uniprotkb:Alpha-tubulin ubiquitous(gene name synonym)|uniprotkb:Tubulin K-alpha-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481382|imex:IM-26985-255 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000005302(gene)|ensembl:ENST00000312196(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016573"(histone acetylation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0046972"("histone acetyltransferase activity (H4-K16 specific)")|go:"GO:0072487"(MSL complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008676(MRG)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR026541|interpro:IPR037921|interpro:IPR038217|mint:Q8N5Y2|rcsb pdb:2Y0N|rcsb pdb:3OA6|rcsb pdb:3OB9|reactome:R-HSA-3214847|refseq:NP_001180199.1|refseq:NP_523352.1|refseq:NP_523353.2|refseq:NP_006791.2|refseq:NP_001269103.1|refseq:XP_005274497.1|dip:DIP-56857N refseq:NP_006073.2|ensembl:ENSG00000123416(gene)|ensembl:ENST00000336023(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-983189|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|go:"GO:0045121"(membrane raft)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68363|rcsb pdb:2E4H|rcsb pdb:5IJ0|rcsb pdb:5IJ9|rcsb pdb:5N5N|rcsb pdb:6E7B|rcsb pdb:6E7C|rcsb pdb:6I2I|go:"GO:0051301"(cell division)|rcsb pdb:6J4V|rcsb pdb:6J8O|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|rcsb pdb:6S8L|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9013407|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-2132295|reactome:R-HSA-9668328 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:uZsUcEHPwWI+o+d7aGwhfnxVltA9606 rogid:D4YpuLCXl/S+53qV7P7sF81aARY9606 rigid:mfnpTUnkT+b8PuFvtI15datBDKI false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N5Y2 uniprotkb:Q9HCI7 intact:EBI-2560796|ensembl:ENSP00000312244|uniprotkb:Q9Y5Z8|uniprotkb:Q9UG70|uniprotkb:B7Z227|uniprotkb:B4DUV8|uniprotkb:A6NCU2|uniprotkb:A6NHW8|uniprotkb:A8K165 intact:EBI-2560775|uniprotkb:Q8NDB4|uniprotkb:Q9NVS4|uniprotkb:Q0D2P1|ensembl:ENSP00000311827|uniprotkb:B4DYL4|uniprotkb:G5E9I1 psi-mi:ms3l1_human(display_long)|uniprotkb:MSL3(gene name)|psi-mi:MSL3(display_short)|uniprotkb:MSL3L1(gene name synonym)|uniprotkb:Male-specific lethal-3 protein-like 1(gene name synonym)|uniprotkb:Male-specific lethal-3 homolog 1(gene name synonym) psi-mi:msl2_human(display_long)|uniprotkb:MSL2(gene name)|psi-mi:MSL2(display_short)|uniprotkb:KIAA1585(gene name synonym)|uniprotkb:MSL2L1(gene name synonym)|uniprotkb:RNF184(gene name synonym)|uniprotkb:Male-specific lethal 2-like 1(gene name synonym)|uniprotkb:Male-specific lethal-2 homolog 1(gene name synonym)|uniprotkb:RING finger protein 184(gene name synonym)|uniprotkb:E3 ubiquitin-protein transferase MSL2(gene name synonym)|uniprotkb:Male-specific lethal-2 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481382|imex:IM-26985-255 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000005302(gene)|ensembl:ENST00000312196(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016573"(histone acetylation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0046972"("histone acetyltransferase activity (H4-K16 specific)")|go:"GO:0072487"(MSL complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008676(MRG)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR026541|interpro:IPR037921|interpro:IPR038217|mint:Q8N5Y2|rcsb pdb:2Y0N|rcsb pdb:3OA6|rcsb pdb:3OB9|reactome:R-HSA-3214847|refseq:NP_001180199.1|refseq:NP_523352.1|refseq:NP_523353.2|refseq:NP_006791.2|refseq:NP_001269103.1|refseq:XP_005274497.1|dip:DIP-56857N refseq:NP_001138889.1|refseq:NP_060603.2|refseq:XP_011511251.1|ensembl:ENSG00000174579(gene)|ensembl:ENST00000309993(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0072487"(MSL complex)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR032043|interpro:IPR032049|interpro:IPR033467|interpro:IPR037922|mint:Q9HCI7|rcsb pdb:4B7Y|rcsb pdb:4B86|reactome:R-HSA-3214847|refseq:XP_005247628.1|refseq:XP_006713747.1 - - comment:"author score: 58" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:uZsUcEHPwWI+o+d7aGwhfnxVltA9606 rogid:kJp6Yylwcfca/FBNpVGo7y8pbcE9606 rigid:mfnpTUnkT+b8PuFvtI15datBDKI false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N5Y2 uniprotkb:Q9H7Z6 intact:EBI-2560796|ensembl:ENSP00000312244|uniprotkb:Q9Y5Z8|uniprotkb:Q9UG70|uniprotkb:B7Z227|uniprotkb:B4DUV8|uniprotkb:A6NCU2|uniprotkb:A6NHW8|uniprotkb:A8K165 intact:EBI-896414|uniprotkb:Q659G0|uniprotkb:Q7LC17|uniprotkb:Q8IY59|uniprotkb:Q8WYB4|uniprotkb:Q8WZ14|uniprotkb:Q9HAC5|uniprotkb:Q9NR35|uniprotkb:A8K4Z1|intact:EBI-2560822|uniprotkb:G5E9P2|ensembl:ENSP00000219797|ensembl:ENSP00000456933 psi-mi:ms3l1_human(display_long)|uniprotkb:MSL3(gene name)|psi-mi:MSL3(display_short)|uniprotkb:MSL3L1(gene name synonym)|uniprotkb:Male-specific lethal-3 protein-like 1(gene name synonym)|uniprotkb:Male-specific lethal-3 homolog 1(gene name synonym) psi-mi:kat8_human(display_long)|uniprotkb:KAT8(gene name)|psi-mi:KAT8(display_short)|uniprotkb:MOF(gene name synonym)|uniprotkb:PP7073(orf name)|uniprotkb:MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1(gene name synonym)|uniprotkb:MYST1(gene name synonym)|uniprotkb:Lysine acetyltransferase 8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481382|imex:IM-26985-255 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000005302(gene)|ensembl:ENST00000312196(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016573"(histone acetylation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0046972"("histone acetyltransferase activity (H4-K16 specific)")|go:"GO:0072487"(MSL complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008676(MRG)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR026541|interpro:IPR037921|interpro:IPR038217|mint:Q8N5Y2|rcsb pdb:2Y0N|rcsb pdb:3OA6|rcsb pdb:3OB9|reactome:R-HSA-3214847|refseq:NP_001180199.1|refseq:NP_523352.1|refseq:NP_523353.2|refseq:NP_006791.2|refseq:NP_001269103.1|refseq:XP_005274497.1|dip:DIP-56857N refseq:NP_115564.2|refseq:NP_892003.2|ensembl:ENSG00000103510(gene)|ensembl:ENST00000219797(transcript)|ensembl:ENST00000543774(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000776"(kinetochore)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0043995"("histone acetyltransferase activity (H4-K5 specific)")|go:"GO:0043996"("histone acetyltransferase activity (H4-K8 specific)")|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046972"("histone acetyltransferase activity (H4-K16 specific)")|go:"GO:0071339"(MLL1 complex)|go:"GO:0072487"(MSL complex)|interpro:IPR000953(Chromo domain)|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR036388|interpro:IPR037906|interpro:IPR040706|mint:Q9H7Z6|rcsb pdb:2GIV|rcsb pdb:2PQ8|rcsb pdb:2Y0M|rcsb pdb:3QAH|rcsb pdb:3TOA|rcsb pdb:3TOB|rcsb pdb:4DNC|rcsb pdb:5H43|rcsb pdb:5J8C|rcsb pdb:5J8F|rcsb pdb:5WCI|rcsb pdb:6BA2|rcsb pdb:6BA4|rcsb pdb:6CT2|rcsb pdb:6OIN|rcsb pdb:6OIO|rcsb pdb:6OIP|rcsb pdb:6OIQ|rcsb pdb:6OIR|rcsb pdb:6OWH|rcsb pdb:6OWI|rcsb pdb:6PD8|rcsb pdb:6PD9|rcsb pdb:6PDA|rcsb pdb:6PDB|rcsb pdb:6PDC|rcsb pdb:6PDD|rcsb pdb:6PDE|rcsb pdb:6PDF|rcsb pdb:6PDG|rcsb pdb:7CMR|reactome:R-HSA-3214847 - - comment:"author score: 97" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:uZsUcEHPwWI+o+d7aGwhfnxVltA9606 rogid:CIkEOWd9OuFyigFJ02ORCqVbXHE9606 rigid:mfnpTUnkT+b8PuFvtI15datBDKI false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N5Y2 uniprotkb:Q68DK7 intact:EBI-2560796|ensembl:ENSP00000312244|uniprotkb:Q9Y5Z8|uniprotkb:Q9UG70|uniprotkb:B7Z227|uniprotkb:B4DUV8|uniprotkb:A6NCU2|uniprotkb:A6NHW8|uniprotkb:A8K165 intact:EBI-2560816|ensembl:ENSP00000381543|uniprotkb:Q69Z03|uniprotkb:Q0VF46|intact:EBI-2654071 psi-mi:ms3l1_human(display_long)|uniprotkb:MSL3(gene name)|psi-mi:MSL3(display_short)|uniprotkb:MSL3L1(gene name synonym)|uniprotkb:Male-specific lethal-3 protein-like 1(gene name synonym)|uniprotkb:Male-specific lethal-3 homolog 1(gene name synonym) psi-mi:msl1_human(display_long)|uniprotkb:MSL1(gene name)|psi-mi:MSL1(display_short)|uniprotkb:MSL1L1(gene name synonym)|uniprotkb:Male-specific lethal 1-like 1(gene name synonym)|uniprotkb:Male-specific lethal-1 homolog 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481382|imex:IM-26985-255 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000005302(gene)|ensembl:ENST00000312196(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016573"(histone acetylation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0046972"("histone acetyltransferase activity (H4-K16 specific)")|go:"GO:0072487"(MSL complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008676(MRG)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR026541|interpro:IPR037921|interpro:IPR038217|mint:Q8N5Y2|rcsb pdb:2Y0N|rcsb pdb:3OA6|rcsb pdb:3OB9|reactome:R-HSA-3214847|refseq:NP_001180199.1|refseq:NP_523352.1|refseq:NP_523353.2|refseq:NP_006791.2|refseq:NP_001269103.1|refseq:XP_005274497.1|dip:DIP-56857N ensembl:ENSG00000188895(gene)|ensembl:ENST00000398532(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016607"(nuclear speck)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0072487"(MSL complex)|interpro:IPR026711|interpro:IPR029332|interpro:IPR031840|mint:Q68DK7|rcsb pdb:4B7Y|rcsb pdb:4B86|rcsb pdb:4DNC|reactome:R-HSA-3214847|refseq:NP_001012241.1|refseq:XP_005257355.1|dip:DIP-56862N - - comment:"author score: 134" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:uZsUcEHPwWI+o+d7aGwhfnxVltA9606 rogid:sFenPEZNoGtpn1bDFoUzSJBPUBY9606 rigid:mfnpTUnkT+b8PuFvtI15datBDKI false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14777 uniprotkb:Q8WXF1 intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597 intact:EBI-1392258|uniprotkb:Q5JTQ3|uniprotkb:Q8NCZ9|uniprotkb:Q8WXE8|uniprotkb:Q9NV36|ensembl:ENSP00000343966|ensembl:ENSP00000481916 psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym) psi-mi:pspc1_human(display_long)|uniprotkb:PSPC1(gene name)|psi-mi:PSPC1(display_short)|uniprotkb:PSP1(gene name synonym)|uniprotkb:Paraspeckle protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481572|imex:IM-26985-189 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N refseq:XP_006719907.1|refseq:NP_001035879.1|dip:DIP-39028N|refseq:XP_016876139.1|ensembl:ENSG00000121390(gene)|ensembl:ENST00000338910(transcript)|ensembl:ENST00000619300(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034522|interpro:IPR034523|interpro:IPR035979|mint:Q8WXF1|rcsb pdb:3SDE|rcsb pdb:5IFN|rcsb pdb:5WPA - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606 rogid:voQ5zJMl7FYato9iDkUYfzZ3q/k9606 rigid:9CIjLRFrb8yt9pJ/nftgqbfmVbc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14777 uniprotkb:Q9HBM1 intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597 intact:EBI-999909|ensembl:ENSP00000282074|ensembl:ENSP00000481354|ensembl:ENSP00000483050|uniprotkb:D3DPC0|uniprotkb:A8K4X8 psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym) psi-mi:spc25_human(display_long)|uniprotkb:AD024(orf name)|uniprotkb:SPC25(gene name)|psi-mi:SPC25(display_short)|uniprotkb:SPBC25(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481572|imex:IM-26985-189 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N refseq:NP_065726.1|ensembl:ENSG00000277909(gene)|ensembl:ENST00000282074(transcript)|ensembl:ENST00000611144(transcript)|ensembl:ENST00000616584(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|interpro:IPR013255(Kinetochore-Ndc80 subunit Spc25)|mint:Q9HBM1|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENSG00000152253(gene)|dip:DIP-35753N - - comment:"author score: 82" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606 rogid:qR1LJPKAJwXtOdzKs4Zg0PqJrBM9606 rigid:9CIjLRFrb8yt9pJ/nftgqbfmVbc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14777 uniprotkb:Q8NBT2 intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597 intact:EBI-999900|uniprotkb:C9JGC4|ensembl:ENSP00000465075|uniprotkb:B4DZZ7 psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym) psi-mi:spc24_human(display_long)|uniprotkb:SPBC24(gene name synonym)|uniprotkb:SPC24(gene name)|psi-mi:SPC24(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481572|imex:IM-26985-189 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N refseq:NP_872319.1|ensembl:ENSG00000161888(gene)|ensembl:ENST00000592540(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0051301"(cell division)|interpro:IPR013252(Kinetochore-Ndc80 subunit Spc24)|mint:Q8NBT2|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|refseq:NP_001303960.1|refseq:NP_001303962.1|refseq:XP_005259810.1|dip:DIP-35754N - - comment:"author score: 88" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606 rogid:ANMEuzMkpwcbiSjx6OaHAK8vVcA9606 rigid:9CIjLRFrb8yt9pJ/nftgqbfmVbc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14777 uniprotkb:Q14247 intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597 intact:EBI-351886|intact:EBI-3959948|ensembl:ENSP00000301843|ensembl:ENSP00000500756|uniprotkb:Q8N707|uniprotkb:Q96H99 psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym) psi-mi:src8_human(display_long)|uniprotkb:CTTN(gene name)|psi-mi:CTTN(display_short)|uniprotkb:EMS1(gene name synonym)|uniprotkb:Amplaxin(gene name synonym)|uniprotkb:Oncogene EMS1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481572|imex:IM-26985-189 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N refseq:NP_005222.2|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097581"(lamellipodium organization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR015503(Cortactin)|interpro:IPR035716|interpro:IPR036028|mint:Q14247|rcsb pdb:1X69|rcsb pdb:2D1X|reactome:R-HSA-5627123|reactome:R-HSA-8856828|ensembl:ENSG00000085733(gene)|ensembl:ENSG00000288401(gene)|ensembl:ENST00000301843(transcript)|ensembl:ENST00000671805(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|refseq:NP_001171669.1|refseq:NP_612632.1|dip:DIP-33190N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606 rogid:uzhAnL5Fu9Mgg9/LWeNiaYIwNVU9606 rigid:9CIjLRFrb8yt9pJ/nftgqbfmVbc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14777 uniprotkb:Q99417 intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597 intact:EBI-716185|intact:EBI-2559925|uniprotkb:Q5TA64|uniprotkb:Q96HE2|uniprotkb:B2R4N0|ensembl:ENSP00000380702 psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym) psi-mi:mycbp_human(display_long)|uniprotkb:Associate of Myc 1(gene name synonym)|uniprotkb:MYCBP(gene name)|psi-mi:MYCBP(display_short)|uniprotkb:AMY1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481572|imex:IM-26985-189 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N refseq:NP_036465.2|ensembl:ENSG00000214114(gene)|ensembl:ENST00000397572(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007283"(spermatogenesis)|interpro:IPR026060|mint:Q99417|rcsb pdb:2YY0 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606 rogid:jIStn1A10DDkgTuwVeKpDPJ6tIs9606 rigid:9CIjLRFrb8yt9pJ/nftgqbfmVbc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14777 uniprotkb:Q8WWM7 intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597 intact:EBI-948363|ensembl:ENSP00000338718|uniprotkb:O95135|uniprotkb:Q6NVJ8|uniprotkb:Q6PJW6|uniprotkb:Q8IU61|uniprotkb:Q8IU95|uniprotkb:Q8WWM3|uniprotkb:Q8WWM4|uniprotkb:Q8WWM5|uniprotkb:Q8WWM6|uniprotkb:Q99703|uniprotkb:B9EGM2|uniprotkb:E9PAR9|uniprotkb:A8K1R6|uniprotkb:Q63ZY4 psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym) psi-mi:atx2l_human(display_long)|uniprotkb:Ataxin-2 domain protein(gene name synonym)|uniprotkb:Ataxin-2-related protein(gene name synonym)|uniprotkb:ATXN2L(gene name)|psi-mi:ATXN2L(display_short)|uniprotkb:A2D(gene name synonym)|uniprotkb:A2LG(gene name synonym)|uniprotkb:A2LP(gene name synonym)|uniprotkb:A2RP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481572|imex:IM-26985-189 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N ensembl:ENSG00000168488(gene)|ensembl:ENST00000336783(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045296"(cadherin binding)|interpro:IPR009604(Ataxin-2, N-terminal)|interpro:IPR009818(Ataxin-2, C-terminal)|interpro:IPR025852|mint:Q8WWM7|refseq:NP_009176.2|refseq:NP_663760.1|refseq:NP_680780.1|refseq:NP_680781.1|refseq:XP_005255123.1|refseq:NP_059867.3|refseq:NP_680782.1 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606 rogid:t7lrS10IM/5pt+rrbqBRowZ6b+09606 rigid:9CIjLRFrb8yt9pJ/nftgqbfmVbc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14777 uniprotkb:P50750 intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597 intact:EBI-1383449|uniprotkb:Q5JU24|uniprotkb:Q5JU25|uniprotkb:Q5U006|uniprotkb:Q96TF1|ensembl:ENSP00000362361 psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym) psi-mi:cdk9_human(display_long)|uniprotkb:CDK9(gene name)|psi-mi:CDK9(display_short)|uniprotkb:CDC2L4(gene name synonym)|uniprotkb:Cell division protein kinase 9(gene name synonym)|uniprotkb:Serine/threonine-protein kinase PITALRE(gene name synonym)|uniprotkb:Cell division cycle 2-like protein kinase 4(gene name synonym)|uniprotkb:C-2K(gene name synonym)|uniprotkb:TAK(gene name synonym)|uniprotkb:Tat-associated kinase complex catalytic subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481572|imex:IM-26985-189 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N refseq:NP_001252.1|dip:DIP-29016N|rcsb pdb:4BCI|rcsb pdb:4BCJ|rcsb pdb:4EC8|rcsb pdb:4EC9|rcsb pdb:4IMY|rcsb pdb:4OGR|rcsb pdb:4OR5|rcsb pdb:5L1Z|rcsb pdb:6CYT|rcsb pdb:6GZH|rcsb pdb:6Z45|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-176034|reactome:R-HSA-2173796|rcsb pdb:3MY1|rcsb pdb:3TN8|rcsb pdb:3TNH|rcsb pdb:3TNI|rcsb pdb:4BCF|rcsb pdb:4BCG|rcsb pdb:4BCH|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|reactome:R-HSA-9018519|ensembl:ENSG00000136807(gene)|ensembl:ENST00000373264(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008024"(cyclin/CDK positive transcription elongation factor complex)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008353"(RNA polymerase II CTD heptapeptide repeat kinase activity)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0016605"(PML body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031056"(regulation of histone modification)|go:"GO:0031297"(replication fork processing)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070691"(P-TEFb complex)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1903839"(positive regulation of mRNA 3'-UTR binding)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P50750|rcsb pdb:1PF6|rcsb pdb:3BLH|rcsb pdb:3BLQ|rcsb pdb:3BLR|rcsb pdb:3LQ5|rcsb pdb:3MI9|rcsb pdb:3MIA - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606 rogid:XSEmM4b5tp/WCJCJxnQYyP0stvM9606 rigid:9CIjLRFrb8yt9pJ/nftgqbfmVbc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14777 uniprotkb:O43290 intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597 intact:EBI-607761|ensembl:ENSP00000310448|uniprotkb:A6NDN1|uniprotkb:Q53GB5 psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym) psi-mi:snut1_human(display_long)|uniprotkb:U4/U6.U5 tri-snRNP-associated 110 kDa protein(gene name synonym)|uniprotkb:SART1(gene name)|psi-mi:SART1(display_short)|uniprotkb:SNU66 homolog(gene name synonym)|uniprotkb:Squamous cell carcinoma antigen recognized by T-cells 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481572|imex:IM-26985-189 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N ensembl:ENSG00000175467(gene)|ensembl:ENST00000312397(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000481"(maturation of 5S rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0045585"(positive regulation of cytotoxic T cell differentiation)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR005011(SART-1 protein)|mint:O43290|rcsb pdb:4PYU|rcsb pdb:5O9Z|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|reactome:R-HSA-72163|refseq:NP_005137.1|dip:DIP-33360N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606 rogid:egvWHy7UXW+MkGtGEW984yvRU9k9606 rigid:9CIjLRFrb8yt9pJ/nftgqbfmVbc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14777 uniprotkb:Q9H0G5 intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597 intact:EBI-5464397|uniprotkb:Q6FI71|ensembl:ENSP00000247026 psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym) psi-mi:nsrp1_human(display_long)|uniprotkb:NSRP1(gene name)|psi-mi:NSRP1(display_short)|uniprotkb:CCDC55(gene name synonym)|uniprotkb:NSRP70(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 55(gene name synonym)|uniprotkb:Nuclear speckle-related protein 70(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481572|imex:IM-26985-189 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N refseq:NP_115517.1|refseq:NP_001248396.1|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0032502"(developmental process)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR018612|interpro:IPR042816|mint:Q9H0G5|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000126653(gene)|ensembl:ENST00000247026(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus) - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606 rogid:Hp8MjUsGzGZWl+Y/zyzkOxjnLc49606 rigid:9CIjLRFrb8yt9pJ/nftgqbfmVbc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14777 uniprotkb:Q6UXN9 intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597 intact:EBI-1176082|uniprotkb:Q8TEB2|uniprotkb:A8K5R5|intact:EBI-2562464|ensembl:ENSP00000296490 psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym) psi-mi:wdr82_human(display_long)|uniprotkb:Protein TMEM113(gene name synonym)|uniprotkb:TMEM113(gene name synonym)|uniprotkb:WDR82(gene name)|psi-mi:WDR82(display_short)|uniprotkb:Swd2(gene name synonym)|uniprotkb:WDR82A(gene name synonym)|uniprotkb:UNQ9342/PRO34047(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481572|imex:IM-26985-189 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N refseq:NP_079498.2|ensembl:ENSG00000164091(gene)|ensembl:ENST00000296490(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005730"(nucleolus)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|interpro:IPR037867|mint:Q6UXN9 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606 rogid:0TyKYwpTLd22Cm+ihT1+n0oo12c9606 rigid:9CIjLRFrb8yt9pJ/nftgqbfmVbc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14777 uniprotkb:Q86XP3 intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597 intact:EBI-722353|uniprotkb:A6NML1|uniprotkb:O75619|uniprotkb:Q68G51|uniprotkb:Q96BK1|uniprotkb:Q96HR7|uniprotkb:Q9Y3V8|uniprotkb:A8KA43|intact:EBI-2555393|ensembl:ENSP00000374574|ensembl:ENSP00000463561|ensembl:ENSP00000464050 psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym) psi-mi:ddx42_human(display_long)|uniprotkb:DEAD box protein 42(gene name synonym)|uniprotkb:Splicing factor 3B-associated 125 kDa protein(gene name synonym)|uniprotkb:RNA helicase-related protein(gene name synonym)|uniprotkb:RNA helicase-like protein(gene name synonym)|uniprotkb:SF3b DEAD box protein(gene name synonym)|uniprotkb:DDX42(gene name)|psi-mi:DDX42(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481572|imex:IM-26985-189 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N refseq:NP_031398.2|refseq:NP_987095.1|refseq:XP_006721720.1|refseq:XP_016879600.1|ensembl:ENSG00000198231(gene)|ensembl:ENST00000389924(transcript)|ensembl:ENST00000578681(transcript)|ensembl:ENST00000583590(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008104"(protein localization)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q86XP3|reactome:R-HSA-72163|reactome:R-HSA-72165 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606 rogid:3vZn92rr6cO8qSZJdyq1fguSc489606 rigid:9CIjLRFrb8yt9pJ/nftgqbfmVbc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14777 uniprotkb:Q8N684 intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597 intact:EBI-746909|uniprotkb:C9K0Q4|uniprotkb:Q7Z3H9|uniprotkb:Q9H025|uniprotkb:Q9H9V1|uniprotkb:B3KU04|ensembl:ENSP00000378352 psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym) psi-mi:cpsf7_human(display_long)|uniprotkb:Cleavage and polyadenylation specificity factor 59 kDa subunit(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 59 kDa subunit(gene name synonym)|uniprotkb:CPSF7(gene name)|psi-mi:CPSF7(display_short)|uniprotkb:Cleavage factor Im complex 59 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481572|imex:IM-26985-189 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N refseq:NP_001129512.1|refseq:NP_001136037.1|refseq:NP_079087.3|refseq:XP_011543560.1|refseq:XP_011543561.1|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0016020"(membrane)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034770|interpro:IPR034772|interpro:IPR034773|interpro:IPR035979|mint:Q8N684|rcsb pdb:3N9U|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|ensembl:ENSG00000149532(gene)|ensembl:ENST00000394888(transcript)|refseq:XP_005274356.1|reactome:R-HSA-9013422 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606 rogid:bfliZhw27GRZMSQpYRZ/x/tWGh49606 rigid:9CIjLRFrb8yt9pJ/nftgqbfmVbc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14777 uniprotkb:Q4VCS5 intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597 intact:EBI-2511319|ensembl:ENSP00000361027|uniprotkb:Q504X5|uniprotkb:Q9UPT1|uniprotkb:Q9HD27 psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym) psi-mi:amot_human(display_long)|uniprotkb:AMOT(gene name)|psi-mi:AMOT(display_short)|uniprotkb:KIAA1071(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481572|imex:IM-26985-189 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N ensembl:ENSG00000126016(gene)|ensembl:ENST00000371959(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006935"(chemotaxis)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035329"(hippo signaling)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q4VCS5|rcsb pdb:6JJX|reactome:R-HSA-2028269|refseq:XP_011529177.1|refseq:NP_001106962.1|refseq:NP_573572.1|refseq:XP_005262144.1|refseq:XP_005262147.1|refseq:XP_016884778.1|dip:DIP-53711N - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606 rogid:5O9K+GgX1s0Hn5optTeKPOs+X1s9606 rigid:9CIjLRFrb8yt9pJ/nftgqbfmVbc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14777 uniprotkb:Q8WUA2 intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597 intact:EBI-2513119|ensembl:ENSP00000253329|uniprotkb:B2RD34|uniprotkb:Q7Z3Q5 psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym) psi-mi:ppil4_human(display_long)|uniprotkb:PPIL4(gene name)|psi-mi:PPIL4(display_short)|uniprotkb:Cyclophilin-like protein PPIL4(gene name synonym)|uniprotkb:Rotamase PPIL4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481572|imex:IM-26985-189 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N go:"GO:1901407"(regulation of phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029000|interpro:IPR035538|interpro:IPR035542|interpro:IPR035979|mint:Q8WUA2|reactome:R-HSA-72163|go:"GO:0005829"(cytosol)|ensembl:ENSG00000131013(gene)|ensembl:ENST00000253329(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|refseq:NP_624311.1 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606 rogid:kxM/VRcLUG5M5FAlHuuAKRBKrd89606 rigid:9CIjLRFrb8yt9pJ/nftgqbfmVbc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14777 uniprotkb:Q7Z417 intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597 intact:EBI-1210753|intact:EBI-10172018|uniprotkb:A1L3A7|uniprotkb:Q9P2M5|uniprotkb:A1L3A6|ensembl:ENSP00000225388 psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym) psi-mi:nufp2_human(display_long)|uniprotkb:NUFIP2(gene name)|psi-mi:NUFIP2(display_short)|uniprotkb:KIAA1321(gene name synonym)|uniprotkb:PIG1(orf name)|uniprotkb:FMRP-interacting protein 2(gene name synonym)|uniprotkb:82 kDa FMRP-interacting protein(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 1 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481572|imex:IM-26985-189 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N refseq:NP_065823.1|dip:DIP-29023N|ensembl:ENSG00000108256(gene)|ensembl:ENST00000225388(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR032747|mint:Q7Z417 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606 rogid:zdbkRisveP+8g70umfbEPHTnAgk9606 rigid:9CIjLRFrb8yt9pJ/nftgqbfmVbc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14777 uniprotkb:P26196 intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597 intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754 psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym) psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481572|imex:IM-26985-189 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606 rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606 rigid:9CIjLRFrb8yt9pJ/nftgqbfmVbc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14777 uniprotkb:Q3MHD2 intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597 intact:EBI-725133|uniprotkb:Q86YB1|uniprotkb:Q96NL5|ensembl:ENSP00000293406|ensembl:ENSP00000466718 psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym) psi-mi:lsm12_human(display_long)|uniprotkb:LSM12(gene name)|psi-mi:LSM12(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481572|imex:IM-26985-189 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N refseq:NP_689557.1|ensembl:ENSG00000161654(gene)|ensembl:ENST00000293406(transcript)|ensembl:ENST00000591247(transcript)|interpro:IPR019181|interpro:IPR039683|mint:Q3MHD2 - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606 rogid:SY9HUXXLZyXhttFb+AXkMh0QOek9606 rigid:9CIjLRFrb8yt9pJ/nftgqbfmVbc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14777 uniprotkb:P39019 intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597 intact:EBI-354451|ensembl:ENSP00000469228|ensembl:ENSP00000470004|ensembl:ENSP00000470972 psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym) psi-mi:rs19_human(display_long)|uniprotkb:RPS19(gene name)|psi-mi:RPS19(display_short)|uniprotkb:Small ribosomal subunit protein eS19(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481572|imex:IM-26985-189 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N refseq:NP_001013.1|ensembl:ENSG00000105372(gene)|ensembl:ENST00000593863(transcript)|ensembl:ENST00000598742(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003723"(RNA binding)|ensembl:ENST00000600467(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0007000"(nucleolus organization)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0060265"(positive regulation of respiratory burst involved in inflammatory response)|go:"GO:0060266"(negative regulation of respiratory burst involved in inflammatory response)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001266(Ribosomal protein S19e)|interpro:IPR018277|interpro:IPR036388|interpro:IPR036390|mint:P39019|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001308412.1|refseq:NP_001308413.1 - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606 rogid:3YqdJJJG+2nqoBf3PLu1fs7pVkY9606 rigid:9CIjLRFrb8yt9pJ/nftgqbfmVbc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14777 uniprotkb:P62750 intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597 intact:EBI-353254|uniprotkb:P29316|uniprotkb:Q92774|uniprotkb:P39024|uniprotkb:B2R5B2|ensembl:ENSP00000389103 psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym) psi-mi:rl23a_human(display_long)|uniprotkb:RPL23A(gene name)|psi-mi:RPL23A(display_short)|uniprotkb:Large ribosomal subunit protein uL23(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481572|imex:IM-26985-189 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|refseq:NP_000975.2|ensembl:ENSG00000198242(gene)|ensembl:ENST00000422514(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904841"(TORC2 complex binding)|interpro:IPR001014(Ribosomal protein L23, conserved site)|interpro:IPR005633(Ribosomal protein L23/L25, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR013025(Ribosomal protein L25/L23)|interpro:IPR019985|mint:P62750|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606 rogid:lA1ubRFO9/Tl54Z1dKUzoCKvpAo9606 rigid:9CIjLRFrb8yt9pJ/nftgqbfmVbc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14777 uniprotkb:P23246 intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597 intact:EBI-355453|uniprotkb:P30808|uniprotkb:Q5SZ71|ensembl:ENSP00000349748 psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym) psi-mi:sfpq_human(display_long)|uniprotkb:SFPQ(gene name)|psi-mi:SFPQ(display_short)|uniprotkb:PSF(gene name synonym)|uniprotkb:Polypyrimidine tract-binding protein-associated-splicing factor(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 100 kDa subunit(gene name synonym)|uniprotkb:100 kDa DNA-pairing protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481572|imex:IM-26985-189 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N refseq:NP_005057.1|ensembl:ENSG00000116560(gene)|ensembl:ENST00000357214(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0003723"(RNA binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0042382"(paraspeckles)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0005634"(nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0048511"(rhythmic process)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:1902177"(positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034525|interpro:IPR034526|interpro:IPR035979|mint:P23246|rcsb pdb:4WII|rcsb pdb:4WIJ|rcsb pdb:4WIK|rcsb pdb:5WPA|rcsb pdb:6NCQ|rcsb pdb:6OWJ|rcsb pdb:6WMZ|rcsb pdb:7LRQ|rcsb pdb:7LRU|reactome:R-HSA-8849468|reactome:R-HSA-9635465|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|refseq:XP_005271169.1|refseq:XP_005271170.1|refseq:XP_005271172.1|refseq:XP_016857542.1|refseq:XP_016857543.1|dip:DIP-31272N - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606 rogid:B7mSc6tthLbSHo0qz0SMZBSl3HA9606 rigid:9CIjLRFrb8yt9pJ/nftgqbfmVbc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14777 uniprotkb:Q9H3K6 intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597 intact:EBI-1642537|uniprotkb:A1L454|uniprotkb:A7YDY3|ensembl:ENSP00000331127|ensembl:ENSP00000498355 psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym) psi-mi:bola2_human(display_long)|uniprotkb:BOLA2(gene name)|psi-mi:BOLA2(display_short)|uniprotkb:BOLA2B(gene name)|psi-mi:BOLA2B(display_short)|uniprotkb:BOLA2A(gene name synonym)|uniprotkb:My016(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481572|imex:IM-26985-189 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N refseq:NP_001026997.1|refseq:NP_001034271.1|refseq:NP_001307508.1|refseq:XP_016855107.1|ensembl:ENSG00000169627(gene)|ensembl:ENSG00000183336(gene)|ensembl:ENST00000330978(transcript)|ensembl:ENST00000651894(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|mint:Q9H3K6|reactome:R-HSA-8950505 - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606 rogid:5TcFdmQcwx5trexmXkWp9Arn5zE9606 rigid:9CIjLRFrb8yt9pJ/nftgqbfmVbc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14777 uniprotkb:O43809 intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597 intact:EBI-355720|uniprotkb:Q6IB85|uniprotkb:Q6NE84|ensembl:ENSP00000300291 psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym) psi-mi:cpsf5_human(display_long)|uniprotkb:NUDT21(gene name)|psi-mi:NUDT21(display_short)|uniprotkb:CFIM25(gene name synonym)|uniprotkb:CPSF25(gene name synonym)|uniprotkb:CPSF5(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 25 kDa subunit(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 21(gene name synonym)|uniprotkb:Cleavage factor Im complex 25 kDa subunit(gene name synonym)|uniprotkb:Nudix hydrolase 21(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 68 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481572|imex:IM-26985-189 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N refseq:NP_008937.1|ensembl:ENSG00000167005(gene)|ensembl:ENST00000300291(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006397"(mRNA processing)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0031439"(positive regulation of mRNA cleavage)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042382"(paraspeckles)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|go:"GO:1900365"(positive regulation of mRNA polyadenylation)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:2000738"(positive regulation of stem cell differentiation)|go:"GO:2000975"(positive regulation of pro-B cell differentiation)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR016706(Cleavage and polyadenylation specificity factor, 25 kDa subunit)|mint:O43809|rcsb pdb:2CL3|rcsb pdb:2J8Q|rcsb pdb:3BAP|rcsb pdb:3BHO|rcsb pdb:3MDG|rcsb pdb:3MDI|rcsb pdb:3N9U|rcsb pdb:3P5T|rcsb pdb:3P6Y|rcsb pdb:3Q2S|rcsb pdb:3Q2T|rcsb pdb:5R4P|rcsb pdb:5R4Q|rcsb pdb:5R4R|rcsb pdb:5R4S|rcsb pdb:5R4T|rcsb pdb:5R4U|rcsb pdb:5R64|rcsb pdb:5R65|rcsb pdb:5R66|rcsb pdb:5R67|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|dip:DIP-42502N - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606 rogid:Acad4mYVuS+Eox+X2CH8PYUkGAA9606 rigid:9CIjLRFrb8yt9pJ/nftgqbfmVbc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14777 uniprotkb:P63241 intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597 intact:EBI-373150|uniprotkb:P10159|uniprotkb:Q16182|uniprotkb:Q7L7L3|uniprotkb:Q7Z4L1|uniprotkb:Q9D0G2|uniprotkb:A8K9A0|uniprotkb:D3DTP2|ensembl:ENSP00000336776|ensembl:ENSP00000390677|ensembl:ENSP00000396073|ensembl:ENSP00000458269|ensembl:ENSP00000459196|ensembl:ENSP00000459611|ensembl:ENSP00000499855|ensembl:ENSP00000499995|ensembl:ENSP00000500414|ensembl:ENSP00000500624|ensembl:ENSP00000500717|ensembl:ENSP00000500847 psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym) psi-mi:if5a1_human(display_long)|uniprotkb:EIF5A(gene name)|psi-mi:EIF5A(display_short)|uniprotkb:Eukaryotic initiation factor 5A isoform 1(gene name synonym)|uniprotkb:eIF-4D(gene name synonym)|uniprotkb:Rev-binding factor(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481572|imex:IM-26985-189 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N refseq:NP_001137232.1|refseq:NP_001137233.1|refseq:NP_001137234.1|refseq:NP_001961.1|refseq:XP_005256566.1|ensembl:ENSG00000132507(gene)|ensembl:ENSG00000288145(gene)|ensembl:ENST00000336458(transcript)|ensembl:ENST00000416016(transcript)|ensembl:ENST00000419711(transcript)|ensembl:ENST00000571955(transcript)|ensembl:ENST00000573542(transcript)|ensembl:ENST00000576930(transcript)|ensembl:ENST00000672250(transcript)|ensembl:ENST00000672755(transcript)|ensembl:ENST00000673099(transcript)|ensembl:ENST00000673210(transcript)|ensembl:ENST00000673259(transcript)|ensembl:ENST00000673304(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043022"(ribosome binding)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0045905"(positive regulation of translational termination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0098586"(cellular response to virus)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|interpro:IPR001884("Eukaryotic initiation factor 5A hypusine (eIF-5A)")|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR019769|interpro:IPR020189|mint:P63241|rcsb pdb:1FH4|rcsb pdb:3CPF|rcsb pdb:5DLQ|reactome:R-HSA-204626 - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606 rogid:/smk81DLs+XvrqXmIZpfvdHHauk9606 rigid:9CIjLRFrb8yt9pJ/nftgqbfmVbc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14777 uniprotkb:P11387 intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597 intact:EBI-876302|ensembl:ENSP00000354522|uniprotkb:Q15610|uniprotkb:Q5TFY3|uniprotkb:Q9UJN0|uniprotkb:O43256|uniprotkb:Q12855|uniprotkb:Q12856|uniprotkb:A8KA78|uniprotkb:E1P5W3 psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym) psi-mi:top1_human(display_long)|uniprotkb:DNA topoisomerase I(gene name synonym)|uniprotkb:TOP1(gene name)|psi-mi:TOP1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481572|imex:IM-26985-189 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N ensembl:ENSG00000198900(gene)|ensembl:ENST00000361337(transcript)|go:"GO:0000932"(P-body)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006265"(DNA topological change)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007623"(circadian rhythm)|go:"GO:0012501"(programmed cell death)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032922"(circadian regulation of gene expression)|refseq:NP_003277.1|dip:DIP-36356N|go:"GO:0032993"(protein-DNA complex)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042493"|go:"GO:0043204"(perikaryon)|go:"GO:0097100"(supercoiled DNA binding)|interpro:IPR001631(DNA topoisomerase I, C-terminal)|interpro:IPR008336(DNA topoisomerase I, DNA binding, eukaryotic-type)|interpro:IPR011010(DNA breaking-rejoining enzyme, catalytic core)|interpro:IPR013030(DNA topoisomerase I, DNA binding, mixed alpha/beta motif, eukaryotic-type)|interpro:IPR013034(DNA topoisomerase I, DNA binding, alpha helical motif, eukaryotic-type)|interpro:IPR013499(DNA topoisomerase I, C-terminal, eukaryotic-type)|interpro:IPR013500(DNA topoisomerase I, catalytic core, eukaryotic-type)|interpro:IPR014711(DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type)|interpro:IPR014727(DNA topoisomerase I, catalytic core, alpha/beta subdomain, eukaryotic-type)|interpro:IPR018521|interpro:IPR025834|interpro:IPR036202|mint:P11387|rcsb pdb:1A31|rcsb pdb:1A35|rcsb pdb:1A36|rcsb pdb:1EJ9|rcsb pdb:1K4S|rcsb pdb:1K4T|rcsb pdb:1LPQ|rcsb pdb:1NH3|rcsb pdb:1R49|rcsb pdb:1RR8|rcsb pdb:1RRJ|rcsb pdb:1SC7|rcsb pdb:1SEU|rcsb pdb:1T8I|rcsb pdb:1TL8|reactome:R-HSA-4615885 - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606 rogid:kB+3PVybgNp2mtOmDa7x8sygFuU9606 rigid:9CIjLRFrb8yt9pJ/nftgqbfmVbc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14777 uniprotkb:Q15233 intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597 intact:EBI-350527|ensembl:ENSP00000503233|uniprotkb:O00201|uniprotkb:P30807|uniprotkb:Q12786|uniprotkb:Q9BQC5|ensembl:ENSP00000276079|ensembl:ENSP00000362947|ensembl:ENSP00000406673|ensembl:ENSP00000410299|ensembl:ENSP00000415777|ensembl:ENSP00000503031|ensembl:ENSP00000504314|ensembl:ENSP00000504351|uniprotkb:D3DVV4|uniprotkb:B7Z4C2|uniprotkb:F5GYZ3 psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym) psi-mi:nono_human(display_long)|uniprotkb:NONO(gene name)|psi-mi:NONO(display_short)|uniprotkb:NRB54(gene name synonym)|uniprotkb:54 kDa nuclear RNA- and DNA-binding protein(gene name synonym)|uniprotkb:"p54(nrb)"(gene name synonym)|uniprotkb:55 kDa nuclear protein(gene name synonym)|uniprotkb:NMT55(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 52 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481572|imex:IM-26985-189 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N refseq:NP_001138880.1|refseq:NP_001138881.1|refseq:NP_001138882.1|refseq:NP_031389.3|ensembl:ENSG00000147140(gene)|ensembl:ENST00000276079(transcript)|ensembl:ENST00000373841(transcript)|ensembl:ENST00000420903(transcript)|ensembl:ENST00000450092(transcript)|ensembl:ENST00000454976(transcript)|ensembl:ENST00000677274(transcript)|ensembl:ENST00000677446(transcript)|ensembl:ENST00000677612(transcript)|ensembl:ENST00000678231(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0042382"(paraspeckles)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034552|interpro:IPR035979|mint:Q15233|rcsb pdb:3SDE|rcsb pdb:5IFM|rcsb pdb:6WMZ|rcsb pdb:7LRQ|dip:DIP-29951N - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606 rogid:5W3ooO4h0qh3GKO+WjDrLBhihHA9606 rigid:9CIjLRFrb8yt9pJ/nftgqbfmVbc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14777 uniprotkb:Q9H7H0 intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597 intact:EBI-749353|intact:EBI-948255|uniprotkb:Q9BSH1|uniprotkb:Q9BZH2|uniprotkb:Q9BZH3|ensembl:ENSP00000343041 psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym) psi-mi:met17_human(display_long)|uniprotkb:METT11D1(gene name synonym)|uniprotkb:Protein RSM22 homolog, mitochondrial(gene name synonym)|uniprotkb:METTL17(gene name)|psi-mi:METTL17(display_short)|uniprotkb:Methyltransferase 11 domain-containing protein 1(gene name synonym)|uniprotkb:False p73 target gene protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481572|imex:IM-26985-189 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N refseq:NP_001025162.1|refseq:NP_073571.1|ensembl:ENSG00000165792(gene)|ensembl:ENST00000339374(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006412"(translation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0032259"(methylation)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR015324(Ribosomal protein Rsm22, bacterial-type)|interpro:IPR029063|mint:Q9H7H0 - - comment:"author score: 31" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606 rogid:RAj8jOqwthd7a0Xzi5FWhVKc8OI9606 rigid:9CIjLRFrb8yt9pJ/nftgqbfmVbc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14777 uniprotkb:Q9H7C9 intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597 intact:EBI-10308705|uniprotkb:Q9Y6B1|uniprotkb:Q96AQ4|ensembl:ENSP00000377078|ensembl:ENSP00000431808 psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym) psi-mi:aamdc_human(display_long)|uniprotkb:AAMDC(gene name)|psi-mi:AAMDC(display_short)|uniprotkb:Adipogenesis associated Mth938 domain-containing protein(gene name synonym)|uniprotkb:C11orf67(gene name synonym)|uniprotkb:PTD015(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481572|imex:IM-26985-189 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N refseq:NP_001303886.1|refseq:NP_001303889.1|refseq:NP_001303890.1|refseq:NP_001303891.1|refseq:NP_078960.1|refseq:XP_011543271.1|ensembl:ENSG00000087884(gene)|ensembl:ENST00000393427(transcript)|ensembl:ENST00000526415(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0045600"(positive regulation of fat cell differentiation)|interpro:IPR007523(Protein of unknown function DUF498)|interpro:IPR034096|interpro:IPR036748|mint:Q9H7C9|rcsb pdb:2AB1|rcsb pdb:2Q4Q - - comment:"author score: 33" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606 rogid:K1kfbdCxyGTAglEl+pDfu4NjjMs9606 rigid:9CIjLRFrb8yt9pJ/nftgqbfmVbc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14777 uniprotkb:Q9BZD4 intact:EBI-715849|uniprotkb:Q6PJX2|ensembl:ENSP00000261597 intact:EBI-724102|ensembl:ENSP00000271452|ensembl:ENSP00000356875|uniprotkb:Q8WU69|uniprotkb:Q96HJ4|uniprotkb:Q96Q78 psi-mi:ndc80_human(display_long)|uniprotkb:Kinetochore protein Hec1(gene name synonym)|uniprotkb:Kinetochore-associated protein 2(gene name synonym)|uniprotkb:Highly expressed in cancer protein(gene name synonym)|uniprotkb:Retinoblastoma-associated protein HEC(gene name synonym)|uniprotkb:NDC80(gene name)|psi-mi:NDC80(display_short)|uniprotkb:HEC(gene name synonym)|uniprotkb:KNTC2(gene name synonym)|uniprotkb:HEC1(gene name synonym) psi-mi:nuf2_human(display_long)|uniprotkb:NUF2(gene name)|psi-mi:NUF2(display_short)|uniprotkb:CDCA1(gene name synonym)|uniprotkb:NUF2R(gene name synonym)|uniprotkb:Cell division cycle-associated protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481572|imex:IM-26985-189 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006092.1|ensembl:ENSG00000080986(gene)|ensembl:ENST00000261597(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000940"(outer kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|go:"GO:0016020"(membrane)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1905342"(positive regulation of protein localization to kinetochore)|interpro:IPR005550(HEC/Ndc80p)|interpro:IPR038273|interpro:IPR040967|mint:O14777|rcsb pdb:2IGP|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|dip:DIP-35100N refseq:NP_113611.2|refseq:NP_663735.2|ensembl:ENSG00000143228(gene)|ensembl:ENST00000271452(transcript)|ensembl:ENST00000367900(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0031262"(Ndc80 complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0051383"(kinetochore organization)|interpro:IPR005549(Nuf2)|interpro:IPR038275|mint:Q9BZD4|rcsb pdb:2VE7|rcsb pdb:3IZ0|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|go:"GO:0016020"(membrane)|dip:DIP-36119N - - comment:"author score: 74" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5OsXbZPvJTMWPepp7M+AXlJUQ649606 rogid:jyetvY/NG1CPYYsx5DZ4dVEPdEY9606 rigid:9CIjLRFrb8yt9pJ/nftgqbfmVbc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:P09012 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-607085|ensembl:ENSP00000243563 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:snrpa_human(display_long)|uniprotkb:SNRPA(gene name)|psi-mi:SNRPA(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481539|imex:IM-26985-187 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005685"(U1 snRNP)|go:"GO:0030619"(U1 snRNA binding)|ensembl:ENSG00000077312(gene)|go:"GO:0042802"(identical protein binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034407|interpro:IPR034409|interpro:IPR035979|mint:P09012|rcsb pdb:1AUD|ensembl:ENST00000243563(transcript)|rcsb pdb:1DRZ|rcsb pdb:1DZ5|rcsb pdb:1FHT|rcsb pdb:1M5K|rcsb pdb:1M5O|rcsb pdb:1M5P|rcsb pdb:1M5V|rcsb pdb:1NU4|rcsb pdb:1OIA|rcsb pdb:1SJ3|rcsb pdb:1SJ4|rcsb pdb:1SJF|rcsb pdb:1U6B|rcsb pdb:1URN|rcsb pdb:1VBX|rcsb pdb:1VBY|rcsb pdb:1VBZ|rcsb pdb:1VC0|rcsb pdb:1VC5|rcsb pdb:1VC6|rcsb pdb:1ZZN|rcsb pdb:2A3J|rcsb pdb:2NZ4|rcsb pdb:2OIH|rcsb pdb:2OJ3|rcsb pdb:2U1A|rcsb pdb:3BO2|rcsb pdb:3BO3|rcsb pdb:3BO4|rcsb pdb:3CUL|rcsb pdb:3CUN|rcsb pdb:3EGZ|rcsb pdb:3G8S|rcsb pdb:3G8T|rcsb pdb:3G96|rcsb pdb:3G9C|rcsb pdb:3HHN|rcsb pdb:3IIN|rcsb pdb:3IRW|rcsb pdb:3IWN|rcsb pdb:3K0J|rcsb pdb:3L3C|rcsb pdb:3MUM|rcsb pdb:3MUR|rcsb pdb:3MUT|rcsb pdb:3R1H|rcsb pdb:3R1L|rcsb pdb:3UCU|rcsb pdb:3UCZ|rcsb pdb:3UD3|rcsb pdb:3UD4|rcsb pdb:3MUV|rcsb pdb:3UTR|rcsb pdb:4C4W|rcsb pdb:4PR6|rcsb pdb:4PRF|rcsb pdb:4W90|rcsb pdb:4W92|rcsb pdb:3MXH|rcsb pdb:3P49|rcsb pdb:3PGW|rcsb pdb:4YB1|rcsb pdb:5DDO|rcsb pdb:5DDP|rcsb pdb:5DDQ|rcsb pdb:5DDR|rcsb pdb:5FJ4|rcsb pdb:6LAS|rcsb pdb:6LAU|rcsb pdb:6LAX|rcsb pdb:6LAZ|rcsb pdb:6QX9|rcsb pdb:6SQN|rcsb pdb:6SQQ|rcsb pdb:6SQT|rcsb pdb:6SQV|rcsb pdb:6SR7|rcsb pdb:6XH0|rcsb pdb:6XH1|rcsb pdb:6XH2|rcsb pdb:6XH3|rcsb pdb:7AEP|rcsb pdb:7B0Y|rcsb pdb:7D7V|rcsb pdb:7LHX|reactome:R-HSA-72163|refseq:NP_004587.1|dip:DIP-29407N - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:BJ9zdDzOPs9JYgU8lErj/maq0AY9606 rigid:vJoPA+inwxYSN8rU9sW375CST0c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:O00629 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-396343|uniprotkb:O00190|intact:EBI-28976443|ensembl:ENSP00000334373|uniprotkb:A8K4S6|uniprotkb:D3DNM2 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:ima3_human(display_long)|uniprotkb:KPNA4(gene name)|psi-mi:KPNA4(display_short)|uniprotkb:QIP1(gene name synonym)|uniprotkb:Karyopherin subunit alpha-4(gene name synonym)|uniprotkb:Importin alpha Q1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481539|imex:IM-26985-187 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N refseq:NP_002259.1|ensembl:ENSG00000186432(gene)|ensembl:ENST00000334256(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0031965"(nuclear membrane)|go:"GO:0061608"(nuclear import signal receptor activity)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O00629|rcsb pdb:4UAE|rcsb pdb:5TBK|rcsb pdb:5XZX|rcsb pdb:6BVV|rcsb pdb:6BVZ|rcsb pdb:6BW9|rcsb pdb:6BWA|rcsb pdb:6BWB|rcsb pdb:6WX8|rcsb pdb:7JJL|reactome:R-HSA-1169408|reactome:R-HSA-168276|ensembl:ENSP00000334373|dip:DIP-32982N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:/cng/xZ42E2juzHNOpuQTP+amx89606 rigid:vJoPA+inwxYSN8rU9sW375CST0c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:P52294 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-358383|uniprotkb:Q9BQ56|uniprotkb:Q6IBQ9|intact:EBI-1058734|ensembl:ENSP00000343701|uniprotkb:D3DN93 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:ima5_human(display_long)|uniprotkb:KPNA1(gene name)|psi-mi:KPNA1(display_short)|uniprotkb:RCH2(gene name synonym)|uniprotkb:Karyopherin subunit alpha-1(gene name synonym)|uniprotkb:SRP1-beta(gene name synonym)|uniprotkb:RAG cohort protein 2(gene name synonym)|uniprotkb:Nucleoprotein interactor 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481539|imex:IM-26985-187 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N refseq:NP_002255.3|ensembl:ENSG00000114030(gene)|ensembl:ENST00000344337(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014841"(skeletal muscle satellite cell proliferation)|go:"GO:0014901"(satellite cell activation involved in skeletal muscle regeneration)|go:"GO:0030425"(dendrite)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:P52294|rcsb pdb:2JDQ|rcsb pdb:3TJ3|rcsb pdb:4B18|rcsb pdb:6WX9|reactome:R-HSA-1169408|reactome:R-HSA-140342|reactome:R-HSA-162592|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-180910|reactome:R-HSA-909733|reactome:R-HSA-9636249|dip:DIP-29296N|refseq:XP_005247494.1 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:eha8sOMYqe0OC6eXBA4eJLLsKFs9606 rigid:vJoPA+inwxYSN8rU9sW375CST0c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:P52292 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-349938|uniprotkb:Q9BRU5|ensembl:ENSP00000504685|intact:EBI-28977049|ensembl:ENSP00000332455|ensembl:ENSP00000438483|ensembl:ENSP00000462331|ensembl:ENSP00000463602|ensembl:ENSP00000504655|uniprotkb:B9EJD6|uniprotkb:Q53YE3|intact:EBI-9377406|uniprotkb:Q6NVW7 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:ima1_human(display_long)|uniprotkb:KPNA2(gene name)|psi-mi:KPNA2(display_short)|uniprotkb:RCH1(gene name synonym)|uniprotkb:SRP1(gene name synonym)|uniprotkb:Karyopherin subunit alpha-2(gene name synonym)|uniprotkb:SRP1-alpha(gene name synonym)|uniprotkb:RAG cohort protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481539|imex:IM-26985-187 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N refseq:NP_002257.1|refseq:NP_001307540.1|ensembl:ENST00000330459(transcript)|ensembl:ENST00000537025(transcript)|ensembl:ENST00000579754(transcript)|ensembl:ENST00000584026(transcript)|ensembl:ENST00000677086(transcript)|ensembl:ENST00000679078(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043657"(host cell)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0075506"(entry of viral genome into host nucleus through nuclear pore complex via importin)|go:"GO:0098892"(extrinsic component of postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1903902"(positive regulation of viral life cycle)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:P52292|rcsb pdb:1EFX|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:3FEX|ensembl:ENSG00000182481(gene)|rcsb pdb:3FEY|rcsb pdb:3WPT|rcsb pdb:4E4V|rcsb pdb:4WV6|rcsb pdb:5H43|rcsb pdb:7N8J|reactome:R-HSA-111932|reactome:R-HSA-1169408|reactome:R-HSA-168276|reactome:R-HSA-442729|reactome:R-HSA-5693548|reactome:R-HSA-9018519|ensembl:ENSP00000332455|ensembl:ENSP00000438483|ensembl:ENSP00000462331|ensembl:ENSP00000463602|ensembl:ENSP00000504655|ensembl:ENSP00000504685|dip:DIP-6205N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:DFtAbvPxkzWJO/fRLPGxA6pEEJQ9606 rigid:vJoPA+inwxYSN8rU9sW375CST0c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:Q9UKX7 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-2371082|uniprotkb:O75644|uniprotkb:Q9NPM9|uniprotkb:Q9NPR6|uniprotkb:Q9P1K5|uniprotkb:B2RB15|uniprotkb:B1AHA4|uniprotkb:Q8N6V5|ensembl:ENSP00000345895 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:nup50_human(display_long)|uniprotkb:NUP50(gene name)|psi-mi:NUP50(display_short)|uniprotkb:NPAP60L(gene name synonym)|uniprotkb:Nuclear pore-associated protein 60 kDa-like(gene name synonym)|uniprotkb:PRO1146(orf name)|uniprotkb:Nucleoporin Nup50(gene name synonym)|uniprotkb:50 kDa nucleoporin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481539|imex:IM-26985-187 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N refseq:XP_011528135.1|refseq:NP_009103.2|refseq:NP_705931.1|refseq:XP_006724166.1|refseq:XP_006724167.1|refseq:XP_005261369.1|refseq:XP_005261371.1|refseq:XP_016884026.1|ensembl:ENSG00000093000(gene)|ensembl:ENST00000347635(transcript)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015007("NUP50 (Nucleoporin 50 kDa)")|mint:Q9UKX7|rcsb pdb:2EC1|rcsb pdb:3TJ3|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:tg/qpkdGAm/M6vLvvCzdTCZoxiA9606 rigid:vJoPA+inwxYSN8rU9sW375CST0c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:Q7Z3E1 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-373532|uniprotkb:Q68CY9|uniprotkb:Q86VP4|uniprotkb:Q9Y4P7|uniprotkb:D3DNK6|ensembl:ENSP00000295924|ensembl:ENSP00000418757|ensembl:ENSP00000420612|ensembl:ENSP00000438345 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:parpt_human(display_long)|uniprotkb:PARP7(gene name synonym)|uniprotkb:Poly [ADP-ribose] polymerase 7(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 14(gene name synonym)|uniprotkb:TIPARP(gene name)|psi-mi:TIPARP(display_short)|uniprotkb:TCDD-inducible poly [ADP-ribose] polymerase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481539|imex:IM-26985-187 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N refseq:NP_001171646.1|refseq:NP_001171647.1|refseq:NP_056323.2|ensembl:ENSG00000163659(gene)|ensembl:ENST00000295924(transcript)|ensembl:ENST00000461166(transcript)|ensembl:ENST00000486483(transcript)|ensembl:ENST00000542783(transcript)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001822"(kidney development)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008585"(female gonad development)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030097"(hemopoiesis)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0140289"(protein mono-ADP-ribosylation)|go:"GO:1990404"(protein ADP-ribosylase activity)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR004170(WWE)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR037197|mint:Q7Z3E1|go:"GO:1904612"(response to 2,3,7,8-tetrachlorodibenzodioxine) - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:ODupizIXgatRSdvMEtPwWWN+BoA9606 rigid:vJoPA+inwxYSN8rU9sW375CST0c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:Q9BXP5 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-712721|uniprotkb:A4D2E5|uniprotkb:A6NK22|uniprotkb:Q32MI4|uniprotkb:Q9Y4S4|ensembl:ENSP00000480421|uniprotkb:O95808|uniprotkb:Q9BWP6|uniprotkb:Q9BXP4|uniprotkb:A4D2E6|uniprotkb:B4DJL4|uniprotkb:B4DZA6|uniprotkb:Q6NT74|uniprotkb:Q8TDQ5 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:srrt_human(display_long)|uniprotkb:SRRT(gene name)|psi-mi:SRRT(display_short)|uniprotkb:ASR2(gene name synonym)|uniprotkb:ARS2(gene name synonym)|uniprotkb:Arsenite-resistance protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481539|imex:IM-26985-187 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N ensembl:ENST00000611405(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046685"(response to arsenic-containing substance)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0140262"(mRNA cap binding complex binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007042(Arsenite-resistance protein 2)|interpro:IPR021933|interpro:IPR035979|interpro:IPR039727|mint:Q9BXP5|rcsb pdb:5OO6|rcsb pdb:6F7J|rcsb pdb:6F7P|rcsb pdb:6F7S|rcsb pdb:6F8D|reactome:R-HSA-6807505|reactome:R-HSA-72163|ensembl:ENSG00000087087(gene)|refseq:NP_001122324.1|refseq:NP_001122325.1|refseq:NP_001122326.1|refseq:NP_056992.4 - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:upRnTwa7LTUzxnbGtfpJUejg2+w9606 rigid:vJoPA+inwxYSN8rU9sW375CST0c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:Q09161 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-464743|uniprotkb:Q59G76|uniprotkb:Q5T1V0|ensembl:ENSP00000364289|uniprotkb:B2R718|uniprotkb:Q5T7X2 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:ncbp1_human(display_long)|uniprotkb:NCBP1(gene name)|psi-mi:NCBP1(display_short)|uniprotkb:CBP80(gene name synonym)|uniprotkb:NCBP(gene name synonym)|uniprotkb:80 kDa nuclear cap-binding protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481539|imex:IM-26985-187 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:1905216"(positive regulation of RNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR015172(MIF4G-like, type 1)|interpro:IPR015174(MIF4G-like, type 2)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027159|mint:Q09161|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|go:"GO:0031047"(gene silencing by RNA)|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-167158|ensembl:ENSG00000136937(gene)|ensembl:ENST00000375147(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006406"(mRNA export from nucleus)|refseq:NP_002477.1|dip:DIP-33244N - - comment:"author score: 75" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:VpCpiIQQZAXyOpu4J7G2k6ilhxY9606 rigid:vJoPA+inwxYSN8rU9sW375CST0c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P52298 uniprotkb:Q9H814 intact:EBI-464729|ensembl:ENSP00000326806|uniprotkb:Q14924|uniprotkb:Q2TS50|uniprotkb:B2RE91|uniprotkb:B4DMK7|uniprotkb:E9PAR5 intact:EBI-5667190|uniprotkb:Q9H8W1|ensembl:ENSP00000297540 psi-mi:ncbp2_human(display_long)|uniprotkb:20 kDa nuclear cap-binding protein(gene name synonym)|uniprotkb:NCBP 20 kDa subunit(gene name synonym)|uniprotkb:NCBP-interacting protein 1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 55 protein(gene name synonym)|uniprotkb:NCBP2(gene name)|psi-mi:NCBP2(display_short)|uniprotkb:CBP20(gene name synonym)|uniprotkb:PIG55(orf name) psi-mi:phax_human(display_long)|uniprotkb:RNA U small nuclear RNA export adapter protein(gene name synonym)|uniprotkb:RNUXA(gene name synonym)|uniprotkb:PHAX(gene name)|psi-mi:PHAX(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481539|imex:IM-26985-187 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000114503(gene)|ensembl:ENST00000321256(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0005846"(nuclear cap binding complex)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008380"(RNA splicing)|go:"GO:0017069"(snRNA binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0034518"(RNA cap binding complex)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0046833"(positive regulation of RNA export from nucleus)|go:"GO:0051028"(mRNA transport)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P52298|rcsb pdb:1H2T|rcsb pdb:1H2U|rcsb pdb:1H2V|rcsb pdb:1H6K|rcsb pdb:1N52|rcsb pdb:1N54|rcsb pdb:3FEX|rcsb pdb:3FEY|rcsb pdb:5OO6|rcsb pdb:5OOB|rcsb pdb:6D0Y|rcsb pdb:7ABG|reactome:R-HSA-111367|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167242|reactome:R-HSA-191859|interpro:IPR034148|reactome:R-HSA-674695|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-72203|reactome:R-HSA-73856|reactome:R-HSA-77588|reactome:R-HSA-77595|reactome:R-HSA-8851708|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR027157|refseq:NP_001036005.1|refseq:NP_031388.2|refseq:NP_001294965.1|dip:DIP-33246N refseq:NP_115553.2|rcsb pdb:2XC7|reactome:R-HSA-191859|reactome:R-HSA-6807505|ensembl:ENSG00000164902(gene)|ensembl:ENST00000297540(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006408"(snRNA export from nucleus)|go:"GO:0015030"(Cajal body)|go:"GO:0015031"(protein transport)|go:"GO:0015643"(toxic substance binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043489"(RNA stabilization)|go:"GO:0140262"(mRNA cap binding complex binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR019385|interpro:IPR038092|interpro:IPR039047|mint:Q9H814 - - comment:"author score: 81" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:o6RiNMygBsTpGq5WzXytRBcC+us9606 rogid:5cyoxIMxtl/gBViCRP3lTsoH/RU9606 rigid:vJoPA+inwxYSN8rU9sW375CST0c false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BPX3 uniprotkb:P07477 intact:EBI-970214|uniprotkb:Q9HBI9|ensembl:ENSP00000251496|uniprotkb:Q3MJE0|uniprotkb:Q96SV9|uniprotkb:Q9BUR3|uniprotkb:Q9BVY1|uniprotkb:Q9H914|uniprotkb:Q9H9Z6 intact:EBI-1222902|uniprotkb:A6NJ71|uniprotkb:Q92955|uniprotkb:Q9HAN4|uniprotkb:Q9HAN5|uniprotkb:Q9HAN6|uniprotkb:Q9HAN7|intact:EBI-1760472|intact:EBI-1965533|uniprotkb:A1A509|uniprotkb:Q5NV57|uniprotkb:Q7M4N3|uniprotkb:Q7M4N4|uniprotkb:B2R5I5|ensembl:ENSP00000308720|ensembl:ENSP00000479217 psi-mi:cnd3_human(display_long)|uniprotkb:NCAPG(gene name)|psi-mi:NCAPG(display_short)|uniprotkb:NYMEL3(gene name synonym)|uniprotkb:CAPG(gene name synonym)|uniprotkb:Chromosome-associated protein G(gene name synonym)|uniprotkb:Condensin subunit CAP-G(gene name synonym)|uniprotkb:XCAP-G homolog(gene name synonym)|uniprotkb:Melanoma antigen NY-MEL-3(gene name synonym)|uniprotkb:Non-SMC condensin I complex subunit G(gene name synonym) psi-mi:try1_human(display_long)|uniprotkb:PRSS1(gene name)|psi-mi:PRSS1(display_short)|uniprotkb:TRP1(gene name synonym)|uniprotkb:TRY1(gene name synonym)|uniprotkb:TRYP1(gene name synonym)|uniprotkb:Trypsin I(gene name synonym)|uniprotkb:Cationic trypsinogen(gene name synonym)|uniprotkb:Serine protease 1(gene name synonym)|uniprotkb:Beta-trypsin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481512|imex:IM-26985-339 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000109805(gene)|ensembl:ENST00000251496(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000796"(condensin complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016020"(membrane)|go:"GO:0051301"(cell division)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025977|interpro:IPR027165|mint:Q9BPX3|rcsb pdb:6IGX|reactome:R-HSA-2514853|refseq:NP_071741.2|dip:DIP-34891N refseq:NP_002760.1|ensembl:ENSG00000204983(gene)|ensembl:ENSG00000274247(gene)|ensembl:ENST00000311737(transcript)|ensembl:ENST00000616256(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0007586"(digestion)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0072562"(blood microparticle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|mint:P07477|rcsb pdb:1FXY|rcsb pdb:1TRN|rcsb pdb:2RA3|rcsb pdb:4WWY|rcsb pdb:4WXV|reactome:R-HSA-1592389|reactome:R-HSA-196741 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:G45XQBcnTeSunRz57s6lJErxvjo9606 rogid:2elS/qMYj0sflxilyWfk3KPtGmo9606 rigid:RjV4Y8zQlJ5TmYuYf/rKqRS0OBU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BPX3 uniprotkb:O95347 intact:EBI-970214|uniprotkb:Q9HBI9|ensembl:ENSP00000251496|uniprotkb:Q3MJE0|uniprotkb:Q96SV9|uniprotkb:Q9BUR3|uniprotkb:Q9BVY1|uniprotkb:Q9H914|uniprotkb:Q9H9Z6 intact:EBI-355822|intact:EBI-1058371|uniprotkb:Q9P1P2|uniprotkb:Q6IEE0|ensembl:ENSP00000286398|ensembl:ENSP00000363919|ensembl:ENSP00000363925 psi-mi:cnd3_human(display_long)|uniprotkb:NCAPG(gene name)|psi-mi:NCAPG(display_short)|uniprotkb:NYMEL3(gene name synonym)|uniprotkb:CAPG(gene name synonym)|uniprotkb:Chromosome-associated protein G(gene name synonym)|uniprotkb:Condensin subunit CAP-G(gene name synonym)|uniprotkb:XCAP-G homolog(gene name synonym)|uniprotkb:Melanoma antigen NY-MEL-3(gene name synonym)|uniprotkb:Non-SMC condensin I complex subunit G(gene name synonym) psi-mi:smc2_human(display_long)|uniprotkb:PRO0324(orf name)|uniprotkb:SMC2(gene name)|psi-mi:SMC2(display_short)|uniprotkb:CAPE(gene name synonym)|uniprotkb:SMC2L1(gene name synonym)|uniprotkb:Chromosome-associated protein E(gene name synonym)|uniprotkb:XCAP-E homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481512|imex:IM-26985-339 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000109805(gene)|ensembl:ENST00000251496(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000796"(condensin complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016020"(membrane)|go:"GO:0051301"(cell division)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025977|interpro:IPR027165|mint:Q9BPX3|rcsb pdb:6IGX|reactome:R-HSA-2514853|refseq:NP_071741.2|dip:DIP-34891N refseq:NP_001036015.1|refseq:NP_001036016.1|refseq:NP_006435.2|refseq:XP_011516451.1|refseq:XP_011516455.1|refseq:XP_011516450.1|refseq:NP_001252531.1|refseq:XP_006716996.1|refseq:XP_016869695.1|refseq:XP_016869696.1|refseq:XP_016869697.1|dip:DIP-35422N|ensembl:ENSG00000136824(gene)|ensembl:ENST00000286398(transcript)|ensembl:ENST00000374787(transcript)|ensembl:ENST00000374793(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051383"(kinetochore organization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027120|interpro:IPR027417|interpro:IPR036277|mint:O95347|rcsb pdb:4U4P|reactome:R-HSA-2299718|reactome:R-HSA-2514853 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:G45XQBcnTeSunRz57s6lJErxvjo9606 rogid:k7RHRDmgiucuAOIfh8vjbqnlv3E9606 rigid:RjV4Y8zQlJ5TmYuYf/rKqRS0OBU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BPX3 uniprotkb:Q15021 intact:EBI-970214|uniprotkb:Q9HBI9|ensembl:ENSP00000251496|uniprotkb:Q3MJE0|uniprotkb:Q96SV9|uniprotkb:Q9BUR3|uniprotkb:Q9BVY1|uniprotkb:Q9H914|uniprotkb:Q9H9Z6 intact:EBI-1044041|uniprotkb:Q8N6U3|ensembl:ENSP00000325017|uniprotkb:D3DUR4 psi-mi:cnd3_human(display_long)|uniprotkb:NCAPG(gene name)|psi-mi:NCAPG(display_short)|uniprotkb:NYMEL3(gene name synonym)|uniprotkb:CAPG(gene name synonym)|uniprotkb:Chromosome-associated protein G(gene name synonym)|uniprotkb:Condensin subunit CAP-G(gene name synonym)|uniprotkb:XCAP-G homolog(gene name synonym)|uniprotkb:Melanoma antigen NY-MEL-3(gene name synonym)|uniprotkb:Non-SMC condensin I complex subunit G(gene name synonym) psi-mi:cnd1_human(display_long)|uniprotkb:NCAPD2(gene name)|psi-mi:NCAPD2(display_short)|uniprotkb:CAPD2(gene name synonym)|uniprotkb:KIAA0159(gene name synonym)|uniprotkb:Non-SMC condensin I complex subunit D2(gene name synonym)|uniprotkb:Chromosome condensation-related SMC-associated protein 1(gene name synonym)|uniprotkb:Chromosome-associated protein D2(gene name synonym)|uniprotkb:XCAP-D2 homolog(gene name synonym)|uniprotkb:CNAP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481512|imex:IM-26985-339 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000109805(gene)|ensembl:ENST00000251496(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000796"(condensin complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016020"(membrane)|go:"GO:0051301"(cell division)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025977|interpro:IPR027165|mint:Q9BPX3|rcsb pdb:6IGX|reactome:R-HSA-2514853|refseq:NP_071741.2|dip:DIP-34891N refseq:NP_055680.3|ensembl:ENSG00000010292(gene)|ensembl:ENST00000315579(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0016020"(membrane)|go:"GO:0042393"(histone binding)|go:"GO:0051301"(cell division)|interpro:IPR007673(Non-SMC condensin subunit, XCAP-D2/Cnd1)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024324|interpro:IPR026971|interpro:IPR032682|mint:Q15021|reactome:R-HSA-2514853 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:G45XQBcnTeSunRz57s6lJErxvjo9606 rogid:lFz1E3CjOD76OsuGtokfR7Ujvnw9606 rigid:RjV4Y8zQlJ5TmYuYf/rKqRS0OBU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BPX3 uniprotkb:P68363 intact:EBI-970214|uniprotkb:Q9HBI9|ensembl:ENSP00000251496|uniprotkb:Q3MJE0|uniprotkb:Q96SV9|uniprotkb:Q9BUR3|uniprotkb:Q9BVY1|uniprotkb:Q9H914|uniprotkb:Q9H9Z6 intact:EBI-487083|intact:EBI-1384226|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:Q27I68|ensembl:ENSP00000336799|uniprotkb:Q8WU19 psi-mi:cnd3_human(display_long)|uniprotkb:NCAPG(gene name)|psi-mi:NCAPG(display_short)|uniprotkb:NYMEL3(gene name synonym)|uniprotkb:CAPG(gene name synonym)|uniprotkb:Chromosome-associated protein G(gene name synonym)|uniprotkb:Condensin subunit CAP-G(gene name synonym)|uniprotkb:XCAP-G homolog(gene name synonym)|uniprotkb:Melanoma antigen NY-MEL-3(gene name synonym)|uniprotkb:Non-SMC condensin I complex subunit G(gene name synonym) psi-mi:tba1b_human(display_long)|uniprotkb:TUBA1B(gene name)|psi-mi:TUBA1B(display_short)|uniprotkb:Tubulin alpha-ubiquitous chain(gene name synonym)|uniprotkb:Alpha-tubulin ubiquitous(gene name synonym)|uniprotkb:Tubulin K-alpha-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481512|imex:IM-26985-339 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000109805(gene)|ensembl:ENST00000251496(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000796"(condensin complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016020"(membrane)|go:"GO:0051301"(cell division)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025977|interpro:IPR027165|mint:Q9BPX3|rcsb pdb:6IGX|reactome:R-HSA-2514853|refseq:NP_071741.2|dip:DIP-34891N refseq:NP_006073.2|ensembl:ENSG00000123416(gene)|ensembl:ENST00000336023(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-983189|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|go:"GO:0045121"(membrane raft)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68363|rcsb pdb:2E4H|rcsb pdb:5IJ0|rcsb pdb:5IJ9|rcsb pdb:5N5N|rcsb pdb:6E7B|rcsb pdb:6E7C|rcsb pdb:6I2I|go:"GO:0051301"(cell division)|rcsb pdb:6J4V|rcsb pdb:6J8O|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|rcsb pdb:6S8L|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9013407|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-2132295|reactome:R-HSA-9668328 - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:G45XQBcnTeSunRz57s6lJErxvjo9606 rogid:D4YpuLCXl/S+53qV7P7sF81aARY9606 rigid:RjV4Y8zQlJ5TmYuYf/rKqRS0OBU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BPX3 uniprotkb:Q9NTJ3 intact:EBI-970214|uniprotkb:Q9HBI9|ensembl:ENSP00000251496|uniprotkb:Q3MJE0|uniprotkb:Q96SV9|uniprotkb:Q9BUR3|uniprotkb:Q9BVY1|uniprotkb:Q9H914|uniprotkb:Q9H9Z6 intact:EBI-356173|uniprotkb:A6NLT9|uniprotkb:O95752|uniprotkb:Q8NDL4|uniprotkb:Q9UNT9|uniprotkb:D3DNL8|ensembl:ENSP00000341382|ensembl:ENSP00000349961 psi-mi:cnd3_human(display_long)|uniprotkb:NCAPG(gene name)|psi-mi:NCAPG(display_short)|uniprotkb:NYMEL3(gene name synonym)|uniprotkb:CAPG(gene name synonym)|uniprotkb:Chromosome-associated protein G(gene name synonym)|uniprotkb:Condensin subunit CAP-G(gene name synonym)|uniprotkb:XCAP-G homolog(gene name synonym)|uniprotkb:Melanoma antigen NY-MEL-3(gene name synonym)|uniprotkb:Non-SMC condensin I complex subunit G(gene name synonym) psi-mi:smc4_human(display_long)|uniprotkb:SMC4(gene name)|psi-mi:SMC4(display_short)|uniprotkb:CAPC(gene name synonym)|uniprotkb:SMC4L1(gene name synonym)|uniprotkb:Chromosome-associated polypeptide C(gene name synonym)|uniprotkb:XCAP-C homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481512|imex:IM-26985-339 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000109805(gene)|ensembl:ENST00000251496(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000796"(condensin complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016020"(membrane)|go:"GO:0051301"(cell division)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025977|interpro:IPR027165|mint:Q9BPX3|rcsb pdb:6IGX|reactome:R-HSA-2514853|refseq:NP_071741.2|dip:DIP-34891N refseq:NP_001002800.1|refseq:NP_005487.3|refseq:XP_011510613.1|refseq:NP_001275682.1|ensembl:ENSG00000113810(gene)|ensembl:ENST00000344722(transcript)|ensembl:ENST00000357388(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0010032"(meiotic chromosome condensation)|go:"GO:0016607"(nuclear speck)|go:"GO:0045132"(meiotic chromosome segregation)|go:"GO:0051301"(cell division)|go:"GO:0051383"(kinetochore organization)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041738|mint:Q9NTJ3|rcsb pdb:4U4P|reactome:R-HSA-2299718|reactome:R-HSA-2514853|dip:DIP-32946N - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:G45XQBcnTeSunRz57s6lJErxvjo9606 rogid:+2lnTSgTXZwRawJ/ASBRa6EDgv09606 rigid:RjV4Y8zQlJ5TmYuYf/rKqRS0OBU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BPX3 uniprotkb:Q5T1J5 intact:EBI-970214|uniprotkb:Q9HBI9|ensembl:ENSP00000251496|uniprotkb:Q3MJE0|uniprotkb:Q96SV9|uniprotkb:Q9BUR3|uniprotkb:Q9BVY1|uniprotkb:Q9H914|uniprotkb:Q9H9Z6 intact:EBI-5325274 psi-mi:cnd3_human(display_long)|uniprotkb:NCAPG(gene name)|psi-mi:NCAPG(display_short)|uniprotkb:NYMEL3(gene name synonym)|uniprotkb:CAPG(gene name synonym)|uniprotkb:Chromosome-associated protein G(gene name synonym)|uniprotkb:Condensin subunit CAP-G(gene name synonym)|uniprotkb:XCAP-G homolog(gene name synonym)|uniprotkb:Melanoma antigen NY-MEL-3(gene name synonym)|uniprotkb:Non-SMC condensin I complex subunit G(gene name synonym) psi-mi:chch9_human(display_long)|uniprotkb:CHCHD2P9(gene name)|psi-mi:CHCHD2P9(display_short)|uniprotkb:C9orf49(gene name synonym)|uniprotkb:CHCHD9(gene name synonym)|uniprotkb:Coiled-coil-helix-coiled-coil-helix domain-containing 2 pseudogene 9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481512|imex:IM-26985-339 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000109805(gene)|ensembl:ENST00000251496(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000796"(condensin complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016020"(membrane)|go:"GO:0051301"(cell division)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025977|interpro:IPR027165|mint:Q9BPX3|rcsb pdb:6IGX|reactome:R-HSA-2514853|refseq:NP_071741.2|dip:DIP-34891N go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|mint:Q5T1J5 - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:G45XQBcnTeSunRz57s6lJErxvjo9606 rogid:nxLtnxxMIGeGK2oC3BIhcwkacSs9606 rigid:RjV4Y8zQlJ5TmYuYf/rKqRS0OBU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BPX3 uniprotkb:Q15003 intact:EBI-970214|uniprotkb:Q9HBI9|ensembl:ENSP00000251496|uniprotkb:Q3MJE0|uniprotkb:Q96SV9|uniprotkb:Q9BUR3|uniprotkb:Q9BVY1|uniprotkb:Q9H914|uniprotkb:Q9H9Z6 intact:EBI-1046410|uniprotkb:Q8TB87|ensembl:ENSP00000240423|uniprotkb:B4E189 psi-mi:cnd3_human(display_long)|uniprotkb:NCAPG(gene name)|psi-mi:NCAPG(display_short)|uniprotkb:NYMEL3(gene name synonym)|uniprotkb:CAPG(gene name synonym)|uniprotkb:Chromosome-associated protein G(gene name synonym)|uniprotkb:Condensin subunit CAP-G(gene name synonym)|uniprotkb:XCAP-G homolog(gene name synonym)|uniprotkb:Melanoma antigen NY-MEL-3(gene name synonym)|uniprotkb:Non-SMC condensin I complex subunit G(gene name synonym) psi-mi:cnd2_human(display_long)|uniprotkb:Non-SMC condensin I complex subunit H(gene name synonym)|uniprotkb:Barren homolog protein 1(gene name synonym)|uniprotkb:Chromosome-associated protein H(gene name synonym)|uniprotkb:XCAP-H homolog(gene name synonym)|uniprotkb:NCAPH(gene name)|psi-mi:NCAPH(display_short)|uniprotkb:BRRN(gene name synonym)|uniprotkb:CAPH(gene name synonym)|uniprotkb:KIAA0074(gene name synonym)|uniprotkb:BRRN1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481512|imex:IM-26985-339 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000109805(gene)|ensembl:ENST00000251496(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000796"(condensin complex)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016020"(membrane)|go:"GO:0051301"(cell division)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR025977|interpro:IPR027165|mint:Q9BPX3|rcsb pdb:6IGX|reactome:R-HSA-2514853|refseq:NP_071741.2|dip:DIP-34891N ensembl:ENSG00000121152(gene)|ensembl:ENST00000240423(transcript)|go:"GO:0000796"(condensin complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016020"(membrane)|go:"GO:0051301"(cell division)|interpro:IPR022816|mint:Q15003|rcsb pdb:6IGX|reactome:R-HSA-2514853|refseq:NP_056156.2|refseq:NP_001268641.1|refseq:NP_001268639.1|refseq:NP_001268640.1|dip:DIP-43899N - - comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:G45XQBcnTeSunRz57s6lJErxvjo9606 rogid:1TTe7uDvFBhHAaS2ZcOwfHxyVnk9606 rigid:RjV4Y8zQlJ5TmYuYf/rKqRS0OBU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P49321 uniprotkb:Q01469 intact:EBI-716205|uniprotkb:Q53GW5|uniprotkb:Q5T625|uniprotkb:Q5T622|uniprotkb:Q96A69|uniprotkb:Q9BTW2|uniprotkb:A8K6H2|uniprotkb:B4DQP3|uniprotkb:F5H3J2|uniprotkb:D3DQ07|intact:EBI-28989159|ensembl:ENSP00000255120 intact:EBI-1054073|uniprotkb:B2R4K0|ensembl:ENSP00000297258 psi-mi:nasp_human(display_long)|uniprotkb:NASP(gene name)|psi-mi:NASP(display_short) psi-mi:fabp5_human(display_long)|uniprotkb:Epidermal-type fatty acid-binding protein(gene name synonym)|uniprotkb:Psoriasis-associated fatty acid-binding protein homolog(gene name synonym)|uniprotkb:FABP5(gene name)|psi-mi:FABP5(display_short)|uniprotkb:Fatty acid-binding protein, epidermal(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481494|imex:IM-26985-115 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001182122.1|refseq:NP_002473.2|refseq:NP_689511.2|ensembl:ENSG00000132780(gene)|ensembl:ENST00000350030(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0001824"(blastocyst development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0008584"(male gonad development)|go:"GO:0015031"(protein transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033574"(response to testosterone)|go:"GO:0034080"(CENP-A containing chromatin assembly)|go:"GO:0042393"(histone binding)|go:"GO:0043486"(histone exchange)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019544|interpro:IPR019734|mint:P49321|ensembl:ENSP00000255120|ensembl:ENST00000351223|ensembl:ENSP00000255121|ensembl:ENST00000537798|ensembl:ENSP00000438871|refseq:XP_005270945.1|dip:DIP-47269N refseq:NP_001435.1|ensembl:ENSG00000164687(gene)|ensembl:ENST00000297258(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0008289"(lipid binding)|go:"GO:0008544"(epidermis development)|go:"GO:0010829"(negative regulation of glucose transmembrane transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031392"(regulation of prostaglandin biosynthetic process)|go:"GO:0035360"(positive regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099178"(regulation of retrograde trans-synaptic signaling by endocanabinoid)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990379"(lipid transport across blood-brain barrier)|interpro:IPR000463(Cytosolic fatty-acid binding)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR012674(Calycin)|interpro:IPR031259|mint:Q01469|rcsb pdb:1B56|rcsb pdb:1JJJ|rcsb pdb:4AZM|rcsb pdb:4AZR|rcsb pdb:4LKP|rcsb pdb:4LKT|rcsb pdb:5HZ5|rcsb pdb:5UR9|reactome:R-HSA-163560|reactome:R-HSA-5362517|reactome:R-HSA-6798695 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8BOknyp+vOh6NF+fXZPYbbqFbH49606 rogid:vxp81/mezHcm5oo27QOmAM8Y5dI9606 rigid:oK363fC5tKLT7EJgrCtg1ZresMc false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P49321 uniprotkb:O14929 intact:EBI-716205|uniprotkb:Q53GW5|uniprotkb:Q5T625|uniprotkb:Q5T622|uniprotkb:Q96A69|uniprotkb:Q9BTW2|uniprotkb:A8K6H2|uniprotkb:B4DQP3|uniprotkb:F5H3J2|uniprotkb:D3DQ07|intact:EBI-28989159|ensembl:ENSP00000255120 intact:EBI-2339359|uniprotkb:Q53SU4|uniprotkb:Q53QF0|uniprotkb:Q49A44|uniprotkb:Q6P594|uniprotkb:Q8WWB9|ensembl:ENSP00000264108 psi-mi:nasp_human(display_long)|uniprotkb:NASP(gene name)|psi-mi:NASP(display_short) psi-mi:hat1_human(display_long)|uniprotkb:HAT1(gene name)|psi-mi:HAT1(display_short)|uniprotkb:KAT1(gene name synonym)|uniprotkb:Histone acetyltransferase 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481494|imex:IM-26985-115 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001182122.1|refseq:NP_002473.2|refseq:NP_689511.2|ensembl:ENSG00000132780(gene)|ensembl:ENST00000350030(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0001824"(blastocyst development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0008584"(male gonad development)|go:"GO:0015031"(protein transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033574"(response to testosterone)|go:"GO:0034080"(CENP-A containing chromatin assembly)|go:"GO:0042393"(histone binding)|go:"GO:0043486"(histone exchange)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019544|interpro:IPR019734|mint:P49321|ensembl:ENSP00000255120|ensembl:ENST00000351223|ensembl:ENSP00000255121|ensembl:ENST00000537798|ensembl:ENSP00000438871|refseq:XP_005270945.1|dip:DIP-47269N refseq:NP_003633.1|dip:DIP-52811N|ensembl:ENSG00000128708(gene)|ensembl:ENST00000264108(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006323"(DNA packaging)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006348"|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0007584"(response to nutrient)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR013523(Histone acetyltransferase HAT1, C-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017380(Histone acetyltransferase type B, catalytic subunit)|interpro:IPR019467|interpro:IPR037113|mint:O14929|rcsb pdb:2P0W|rcsb pdb:6VO5|reactome:R-HSA-3214847 - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8BOknyp+vOh6NF+fXZPYbbqFbH49606 rogid:80KgRaid3NeRfAUdTHMQ/r0VuGo9606 rigid:oK363fC5tKLT7EJgrCtg1ZresMc false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P49321 uniprotkb:P68431 intact:EBI-716205|uniprotkb:Q53GW5|uniprotkb:Q5T625|uniprotkb:Q5T622|uniprotkb:Q96A69|uniprotkb:Q9BTW2|uniprotkb:A8K6H2|uniprotkb:B4DQP3|uniprotkb:F5H3J2|uniprotkb:D3DQ07|intact:EBI-28989159|ensembl:ENSP00000255120 intact:EBI-79722|ensembl:ENSP00000352252|ensembl:ENSP00000358160|ensembl:ENSP00000366999|ensembl:ENSP00000480826|ensembl:ENSP00000482271|ensembl:ENSP00000483283|ensembl:ENSP00000484095|ensembl:ENSP00000484638|ensembl:ENSP00000484658|ensembl:ENSP00000484841|ensembl:ENSP00000489282|intact:EBI-1560041|uniprotkb:A0PJT7|uniprotkb:P02295|uniprotkb:P02296|uniprotkb:P16106|uniprotkb:Q6ISV8|uniprotkb:Q6NWP8|uniprotkb:Q6NWP9|uniprotkb:Q6NXU4|uniprotkb:Q71DJ3|uniprotkb:Q93081|uniprotkb:A5PLR1 psi-mi:nasp_human(display_long)|uniprotkb:NASP(gene name)|psi-mi:NASP(display_short) psi-mi:h31_human(display_long)|uniprotkb:H3FA(gene name synonym)|uniprotkb:H3FL(gene name synonym)|uniprotkb:H3FD(gene name synonym)|uniprotkb:H3FI(gene name synonym)|uniprotkb:H3FH(gene name synonym)|uniprotkb:H3FK(gene name synonym)|uniprotkb:H3FF(gene name synonym)|uniprotkb:H3FJ(gene name synonym)|uniprotkb:H3FB(gene name synonym)|uniprotkb:Histone H3/a(gene name synonym)|uniprotkb:Histone H3/b(gene name synonym)|uniprotkb:Histone H3/c(gene name synonym)|uniprotkb:Histone H3/d(gene name synonym)|uniprotkb:Histone H3/f(gene name synonym)|uniprotkb:Histone H3/h(gene name synonym)|uniprotkb:Histone H3/i(gene name synonym)|uniprotkb:Histone H3/j(gene name synonym)|uniprotkb:Histone H3/k(gene name synonym)|uniprotkb:Histone H3/l(gene name synonym)|uniprotkb:H3C1(gene name)|psi-mi:H3C1(display_short)|uniprotkb:HIST1H3A(gene name synonym)|uniprotkb:H3C2(gene name)|psi-mi:H3C2(display_short)|uniprotkb:HIST1H3B(gene name synonym)|uniprotkb:H3C3(gene name)|psi-mi:H3C3(display_short)|uniprotkb:H3FC HIST1H3C(gene name synonym)|uniprotkb:H3C4(gene name)|psi-mi:H3C4(display_short)|uniprotkb:HIST1H3D(gene name synonym)|uniprotkb:H3C6(gene name)|psi-mi:H3C6(display_short)|uniprotkb:HIST1H3E(gene name synonym)|uniprotkb:H3C7(gene name)|psi-mi:H3C7(display_short)|uniprotkb:HIST1H3F(gene name synonym)|uniprotkb:H3C8(gene name)|psi-mi:H3C8(display_short)|uniprotkb:HIST1H3G(gene name synonym)|uniprotkb:H3C10(gene name)|psi-mi:H3C10(display_short)|uniprotkb:HIST1H3H(gene name synonym)|uniprotkb:H3C11(gene name)|psi-mi:H3C11(display_short)|uniprotkb:HIST1H3I(gene name synonym)|uniprotkb:H3C12(gene name)|psi-mi:H3C12(display_short)|uniprotkb:HIST1H3J(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481494|imex:IM-26985-115 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001182122.1|refseq:NP_002473.2|refseq:NP_689511.2|ensembl:ENSG00000132780(gene)|ensembl:ENST00000350030(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0001824"(blastocyst development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0008584"(male gonad development)|go:"GO:0015031"(protein transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033574"(response to testosterone)|go:"GO:0034080"(CENP-A containing chromatin assembly)|go:"GO:0042393"(histone binding)|go:"GO:0043486"(histone exchange)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019544|interpro:IPR019734|mint:P49321|ensembl:ENSP00000255120|ensembl:ENST00000351223|ensembl:ENSP00000255121|ensembl:ENST00000537798|ensembl:ENSP00000438871|refseq:XP_005270945.1|dip:DIP-47269N rcsb pdb:4TN7|rcsb pdb:4U68|rcsb pdb:4UP0|rcsb pdb:4UY4|rcsb pdb:4X3K|rcsb pdb:4Y6L|rcsb pdb:4YHP|rcsb pdb:4YHZ|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z0R|rcsb pdb:4Z2M|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:4QBS|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B31|rcsb pdb:5C11|rcsb pdb:5C13|rcsb pdb:5C3I|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5D6Y|rcsb pdb:5DAH|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5FFV|rcsb pdb:5GH9|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5H6Q|rcsb pdb:5H6R|rcsb pdb:5HJB|rcsb pdb:5HJC|rcsb pdb:5HJD|rcsb pdb:5HYN|rcsb pdb:5IQL|rcsb pdb:5J3V|rcsb pdb:5J9S|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5B2J|rcsb pdb:5JRG|rcsb pdb:5KJH|rcsb pdb:5KJI|rcsb pdb:5KKL|rcsb pdb:5LUG|rcsb pdb:5M5G|rcsb pdb:5MR8|rcsb pdb:5NNC|rcsb pdb:5OY3|rcsb pdb:5SVX|rcsb pdb:5SVY|rcsb pdb:5SZB|rcsb pdb:5SZC|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5T1G|rcsb pdb:5T1I|rcsb pdb:5T8R|rcsb pdb:5TBN|rcsb pdb:5TDR|rcsb pdb:5TDW|rcsb pdb:5U2J|rcsb pdb:5V21|rcsb pdb:5V22|rcsb pdb:5VA6|rcsb pdb:5VAB|rcsb pdb:5VGE|rcsb pdb:5VNB|rcsb pdb:5NND|rcsb pdb:5WLE|rcsb pdb:5WVO|rcsb pdb:5WXG|rcsb pdb:5WXH|rcsb pdb:5WYI|rcsb pdb:5X60|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5XFQ|rcsb pdb:5XFR|rcsb pdb:5XNV|rcsb pdb:5XTZ|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Y20|rcsb pdb:5Y2F|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:6AXJ|rcsb pdb:6AZE|rcsb pdb:6BHD|rcsb pdb:6BHE|rcsb pdb:6BHG|rcsb pdb:6BHH|rcsb pdb:6BHI|rcsb pdb:6D07|rcsb pdb:6D08|rcsb pdb:6E83|rcsb pdb:6E86|rcsb pdb:5WFC|rcsb pdb:6F6D|rcsb pdb:6HTS|rcsb pdb:6IEU|rcsb pdb:6IIS|rcsb pdb:6IIT|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6JXD|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6LS6|rcsb pdb:6LSD|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MIL|rcsb pdb:6MIM|rcsb pdb:6MIN|rcsb pdb:6MIO|rcsb pdb:6MIQ|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6HKT|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2H|rcsb pdb:6V2K|rcsb pdb:6V3N|rcsb pdb:6V41|rcsb pdb:6V92|rcsb pdb:6VIL|rcsb pdb:6WAV|rcsb pdb:6WW4|rcsb pdb:6YIF|rcsb pdb:6YIH|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:6R92|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7KLR|rcsb pdb:7LYC|reactome:R-HSA-1266695|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|ensembl:ENSG00000197153(gene)|ensembl:ENSG00000197409(gene)|ensembl:ENSG00000273983(gene)|ensembl:ENSG00000274750(gene)|ensembl:ENSG00000275379(gene)|ensembl:ENSG00000275714(gene)|ensembl:ENSG00000277775(gene)|ensembl:ENSG00000278828(gene)|ensembl:ENSG00000286522(gene)|ensembl:ENSG00000287080(gene)|ensembl:ENST00000356476(transcript)|ensembl:ENST00000359303(transcript)|ensembl:ENST00000369163(transcript)|ensembl:ENST00000612966(transcript)|ensembl:ENST00000613854(transcript)|ensembl:ENST00000614378(transcript)|ensembl:ENST00000614911(transcript)|ensembl:ENST00000616365(transcript)|ensembl:ENST00000618052(transcript)|ensembl:ENST00000621411(transcript)|ensembl:ENST00000634733(transcript)|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-3247509|reactome:R-HSA-9710421|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060968"(obsolete regulation of gene silencing)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|interpro:IPR009072(Histone-fold)|mint:P68431|rcsb pdb:1CS9|rcsb pdb:1CT6|rcsb pdb:1O9S|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|rcsb pdb:1Q3L|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|rcsb pdb:2B2T|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|rcsb pdb:2B2U|rcsb pdb:2B2V|rcsb pdb:2B2W|rcsb pdb:2C1J|rcsb pdb:2C1N|go:"GO:0016020"(membrane)|rcsb pdb:2CO0|rcsb pdb:2CV5|rcsb pdb:2FSA|rcsb pdb:2KWJ|rcsb pdb:2KWK|rcsb pdb:2L75|rcsb pdb:2LBM|rcsb pdb:2LGG|rcsb pdb:2M0O|reactome:R-HSA-983231|reactome:R-HSA-977225|rcsb pdb:2NDG|rcsb pdb:2OQ6|rcsb pdb:2OT7|rcsb pdb:2OX0|rcsb pdb:2RI7|rcsb pdb:2RR4|rcsb pdb:2UXN|rcsb pdb:2V85|rcsb pdb:2V89|rcsb pdb:2VNF|rcsb pdb:2VPG|rcsb pdb:2X0L|rcsb pdb:3A1B|rcsb pdb:2NDF|rcsb pdb:3AFA|rcsb pdb:3AVR|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3B95|rcsb pdb:3FDT|rcsb pdb:3KMT|rcsb pdb:3KQI|rcsb pdb:3LQI|rcsb pdb:3LQJ|rcsb pdb:3MP1|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O37|rcsb pdb:3QJ6|rcsb pdb:3RIG|rcsb pdb:3RIY|rcsb pdb:3SOU|rcsb pdb:3SOW|rcsb pdb:3U31|rcsb pdb:3U3D|rcsb pdb:3U4S|rcsb pdb:3U5N|rcsb pdb:3U5O|rcsb pdb:3AZK|rcsb pdb:3U5P|rcsb pdb:3UEE|rcsb pdb:3UEF|rcsb pdb:3UII|rcsb pdb:3UIK|rcsb pdb:3V43|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:3ZG6|rcsb pdb:3ZVY|rcsb pdb:4A0J|rcsb pdb:4A0N|rcsb pdb:4A7J|rcsb pdb:3UIG|rcsb pdb:4BD3|rcsb pdb:4C1Q|rcsb pdb:4F4U|rcsb pdb:4F56|rcsb pdb:4FWF|rcsb pdb:4HON|rcsb pdb:4I51|rcsb pdb:4L7X|rcsb pdb:4LK9|rcsb pdb:4LKA|rcsb pdb:4LLB|rcsb pdb:4LXL|rcsb pdb:4N4H|rcsb pdb:4QBQ|rcsb pdb:4QBR|refseq:NP_003520.1|refseq:NP_003521.2|refseq:NP_003522.1|refseq:NP_003523.1|refseq:NP_003524.1|refseq:NP_003525.1|refseq:NP_003526.1|refseq:NP_003527.1|refseq:NP_003528.1|refseq:NP_066298.1|dip:DIP-29371N - - comment:"author score: 32" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8BOknyp+vOh6NF+fXZPYbbqFbH49606 rogid:ood0OohxZHuhsWZtO7U7GMc+LwM9606 rigid:oK363fC5tKLT7EJgrCtg1ZresMc false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P49321 uniprotkb:P01040 intact:EBI-716205|uniprotkb:Q53GW5|uniprotkb:Q5T625|uniprotkb:Q5T622|uniprotkb:Q96A69|uniprotkb:Q9BTW2|uniprotkb:A8K6H2|uniprotkb:B4DQP3|uniprotkb:F5H3J2|uniprotkb:D3DQ07|intact:EBI-28989159|ensembl:ENSP00000255120 intact:EBI-724303|ensembl:ENSP00000264474|uniprotkb:Q6IB90 psi-mi:nasp_human(display_long)|uniprotkb:NASP(gene name)|psi-mi:NASP(display_short) psi-mi:cyta_human(display_long)|uniprotkb:Cystatin-AS(gene name synonym)|uniprotkb:Stefin-A(gene name synonym)|uniprotkb:CSTA(gene name)|psi-mi:CSTA(display_short)|uniprotkb:STF1(gene name synonym)|uniprotkb:STFA(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481494|imex:IM-26985-115 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001182122.1|refseq:NP_002473.2|refseq:NP_689511.2|ensembl:ENSG00000132780(gene)|ensembl:ENST00000350030(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0001824"(blastocyst development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0008584"(male gonad development)|go:"GO:0015031"(protein transport)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033574"(response to testosterone)|go:"GO:0034080"(CENP-A containing chromatin assembly)|go:"GO:0042393"(histone binding)|go:"GO:0043486"(histone exchange)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019544|interpro:IPR019734|mint:P49321|ensembl:ENSP00000255120|ensembl:ENST00000351223|ensembl:ENSP00000255121|ensembl:ENST00000537798|ensembl:ENSP00000438871|refseq:XP_005270945.1|dip:DIP-47269N refseq:NP_005204.1|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR001713(Proteinase inhibitor I25A, stefin A)|mint:P01040|rcsb pdb:1CYU|rcsb pdb:1CYV|rcsb pdb:1DVC|rcsb pdb:1DVD|rcsb pdb:1GD3|rcsb pdb:1GD4|rcsb pdb:1N9J|rcsb pdb:1NB3|rcsb pdb:1NB5|rcsb pdb:3K9M|rcsb pdb:3KFQ|interpro:IPR018073|rcsb pdb:3KSE|reactome:R-HSA-6809371|ensembl:ENSG00000121552(gene)|ensembl:ENST00000264474(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002020"(protease binding)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0045861"(negative regulation of proteolysis) - - comment:"author score: 43" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8BOknyp+vOh6NF+fXZPYbbqFbH49606 rogid:SzbpyWUHlOtItIvffzuwhcqFsDI9606 rigid:oK363fC5tKLT7EJgrCtg1ZresMc false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P22626 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-299649|ensembl:ENSP00000346694|ensembl:ENSP00000349101|ensembl:ENSP00000354021|ensembl:ENSP00000503360|ensembl:ENSP00000503476|ensembl:ENSP00000503514|ensembl:ENSP00000503885|ensembl:ENSP00000504329|uniprotkb:P22627|uniprotkb:A8K064|uniprotkb:Q9UC98|uniprotkb:Q9UDJ2|uniprotkb:A0A024RA27|uniprotkb:A0A024RA61 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:roa2_human(display_long)|uniprotkb:HNRNPA2B1(gene name)|psi-mi:HNRNPA2B1(display_short)|uniprotkb:HNRPA2B1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|ensembl:ENST00000679001(transcript)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0050658"(RNA transport)|ensembl:ENST00000679021(transcript)|go:"GO:0070062"(extracellular exosome)|ensembl:ENST00000679123(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904358"(positive regulation of telomere maintenance via telomere lengthening)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|go:"GO:1990428"(miRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034486|interpro:IPR034489|interpro:IPR035979|mint:P22626|rcsb pdb:1X4B|rcsb pdb:5EN1|rcsb pdb:5HO4|rcsb pdb:5WWE|rcsb pdb:5WWF|rcsb pdb:5WWG|rcsb pdb:6WPQ|rcsb pdb:6WQK|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|ensembl:ENSG00000122566(gene)|ensembl:ENST00000354667(transcript)|ensembl:ENST00000356674(transcript)|ensembl:ENST00000360787(transcript)|ensembl:ENST00000676746(transcript)|ensembl:ENST00000678675(transcript)|refseq:NP_002128.1|refseq:NP_112533.1|dip:DIP-32877N|refseq:XP_005249786.1|refseq:XP_016867598.1|refseq:XP_016867599.1 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:N2NeJVio9eYQULNcdE1KXtd2KPw9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:Q01469 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-1054073|uniprotkb:B2R4K0|ensembl:ENSP00000297258 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:fabp5_human(display_long)|uniprotkb:Epidermal-type fatty acid-binding protein(gene name synonym)|uniprotkb:Psoriasis-associated fatty acid-binding protein homolog(gene name synonym)|uniprotkb:FABP5(gene name)|psi-mi:FABP5(display_short)|uniprotkb:Fatty acid-binding protein, epidermal(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_001435.1|ensembl:ENSG00000164687(gene)|ensembl:ENST00000297258(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0008289"(lipid binding)|go:"GO:0008544"(epidermis development)|go:"GO:0010829"(negative regulation of glucose transmembrane transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031392"(regulation of prostaglandin biosynthetic process)|go:"GO:0035360"(positive regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099178"(regulation of retrograde trans-synaptic signaling by endocanabinoid)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990379"(lipid transport across blood-brain barrier)|interpro:IPR000463(Cytosolic fatty-acid binding)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR012674(Calycin)|interpro:IPR031259|mint:Q01469|rcsb pdb:1B56|rcsb pdb:1JJJ|rcsb pdb:4AZM|rcsb pdb:4AZR|rcsb pdb:4LKP|rcsb pdb:4LKT|rcsb pdb:5HZ5|rcsb pdb:5UR9|reactome:R-HSA-163560|reactome:R-HSA-5362517|reactome:R-HSA-6798695 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:vxp81/mezHcm5oo27QOmAM8Y5dI9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P32119 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-1266300|uniprotkb:P31945|uniprotkb:P32118|uniprotkb:P35701|uniprotkb:Q6FHG4|uniprotkb:Q92763|uniprotkb:Q9UC23|uniprotkb:A8K0C0|ensembl:ENSP00000301522 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:prdx2_human(display_long)|uniprotkb:PRDX2(gene name)|psi-mi:PRDX2(display_short)|uniprotkb:NKEFB(gene name synonym)|uniprotkb:TDPX1(gene name synonym)|uniprotkb:Thioredoxin peroxidase 1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 1(gene name synonym)|uniprotkb:Thiol-specific antioxidant protein(gene name synonym)|uniprotkb:PRP(gene name synonym)|uniprotkb:Natural killer cell-enhancing factor B(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_005800.3|dip:DIP-39882N|ensembl:ENSG00000167815(gene)|ensembl:ENST00000301522(transcript)|go:"GO:0002357"(defense response to tumor cell)|go:"GO:0002536"(respiratory burst involved in inflammatory response)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0010310"(regulation of hydrogen peroxide metabolic process)|go:"GO:0016209"(antioxidant activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030194"(positive regulation of blood coagulation)|go:"GO:0031665"(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042098"(T cell proliferation)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0045581"(negative regulation of T cell differentiation)|go:"GO:0048538"(thymus development)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:P32119|rcsb pdb:1QMV|rcsb pdb:5B8A|rcsb pdb:5B8B|rcsb pdb:5IJT|rcsb pdb:7KIZ|rcsb pdb:7KJ0|rcsb pdb:7KJ1|reactome:R-HSA-3299685|reactome:R-HSA-5628897|reactome:R-HSA-8862803 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:F8+7/3HrAcJq7BjkZaig16mCOO89606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P15311 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-1056902|uniprotkb:P23714|uniprotkb:Q4VX75|uniprotkb:Q96CU8|uniprotkb:Q9NSJ4|uniprotkb:E1P5A8|ensembl:ENSP00000338934|ensembl:ENSP00000356042 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:ezri_human(display_long)|uniprotkb:EZR(gene name)|psi-mi:EZR(display_short)|uniprotkb:VIL2(gene name synonym)|uniprotkb:p81(gene name synonym)|uniprotkb:Cytovillin(gene name synonym)|uniprotkb:Villin-2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N ensembl:ENSP00000338934|ensembl:ENSP00000356042|refseq:NP_001104547.1|refseq:NP_003370.2|ensembl:ENSG00000092820(gene)|ensembl:ENST00000337147(transcript)|ensembl:ENST00000367075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0001726"(ruffle)|go:"GO:0001772"(immunological synapse)|go:"GO:0001931"(uropod)|go:"GO:0001951"(intestinal D-glucose absorption)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022614"(membrane to membrane docking)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030315"(T-tubule)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031623"(receptor internalization)|go:"GO:0031982"(vesicle)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034629"|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|go:"GO:0036064"(ciliary basal body)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0044297"(cell body)|go:"GO:0044393"(microspike)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0045296"(cadherin binding)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051286"(cell tip)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0072697"(protein localization to cell cortex)|go:"GO:0097449"(astrocyte projection)|go:"GO:0097454"(Schwann cell microvillus)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:1902896"(terminal web assembly)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|mint:P15311|rcsb pdb:1NI2|rcsb pdb:4RM8|rcsb pdb:4RM9|rcsb pdb:4RMA|reactome:R-HSA-373752|reactome:R-HSA-437239|reactome:R-HSA-9662360|reactome:R-HSA-9662361|dip:DIP-38868N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:tSSki5dutR2qqs2dyN3TqcHyiyM9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:Q08188 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-1050019|uniprotkb:A8K5N6|uniprotkb:Q32MM0|uniprotkb:O95933|uniprotkb:Q32ML9|uniprotkb:B2RCR6|uniprotkb:D3DVX1|ensembl:ENSP00000370867 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:tgm3_human(display_long)|uniprotkb:Transglutaminase-3(gene name synonym)|uniprotkb:TGM3(gene name)|psi-mi:TGM3(display_short)|uniprotkb:Transglutaminase E(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_003236.3|ensembl:ENSG00000125780(gene)|ensembl:ENST00000381458(transcript)|go:"GO:0003810"(protein-glutamine gamma-glutamyltransferase activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031424"(keratinization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043163"(cell envelope organization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001102(Transglutaminase, N-terminal)|interpro:IPR002931(Transglutaminase-like)|interpro:IPR008958(Transglutaminase, C-terminal)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013808(Transglutaminase, conserved site)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR023608|interpro:IPR036238|interpro:IPR036985|interpro:IPR038765|mint:Q08188|rcsb pdb:1L9M|rcsb pdb:1L9N|rcsb pdb:1NUD|rcsb pdb:1NUF|rcsb pdb:1NUG - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:5UuVUvhYOaQcLJQO2myrilPgFFw9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P09104 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-713154|ensembl:ENSP00000229277|ensembl:ENSP00000437402|ensembl:ENSP00000438873|uniprotkb:Q96J33|uniprotkb:B7Z2X9 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:enog_human(display_long)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Neural enolase(gene name synonym)|uniprotkb:Neuron-specific enolase(gene name synonym)|uniprotkb:Enolase 2(gene name synonym)|uniprotkb:ENO2(gene name)|psi-mi:ENO2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N rcsb pdb:2AKZ|rcsb pdb:3UCC|rcsb pdb:3UCD|rcsb pdb:3UJE|rcsb pdb:3UJF|rcsb pdb:3UJR|rcsb pdb:3UJS|rcsb pdb:4ZA0|rcsb pdb:4ZCW|rcsb pdb:5EU9|rcsb pdb:5IDZ|rcsb pdb:5TD9|rcsb pdb:5TIJ|reactome:R-HSA-70171|reactome:R-HSA-70263|ensembl:ENST00000229277(transcript)|ensembl:ENST00000535366(transcript)|ensembl:ENST00000541477(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0016020"(membrane)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0043204"(perikaryon)|ensembl:ENSG00000111674(gene)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P09104|rcsb pdb:1TE6|rcsb pdb:2AKM|refseq:NP_001966.1 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:gNa8zN8RaWDRXjw/Z0sY6TAa/aA9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:O75475 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-1801773|uniprotkb:O00256|uniprotkb:O95368|uniprotkb:Q6P391|uniprotkb:Q86YB9|uniprotkb:Q9NZI3|uniprotkb:Q9UER6|uniprotkb:D3DRI9|ensembl:ENSP00000370109|ensembl:ENSP00000370114 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:psip1_human(display_long)|uniprotkb:PSIP1(gene name)|psi-mi:PSIP1(display_short)|uniprotkb:DFS70(gene name synonym)|uniprotkb:LEDGF(gene name synonym)|uniprotkb:PSIP2(gene name synonym)|uniprotkb:Lens epithelium-derived growth factor(gene name synonym)|uniprotkb:Transcriptional coactivator p75/p52(gene name synonym)|uniprotkb:Dense fine speckles 70 kDa protein(gene name synonym)|uniprotkb:CLL-associated antigen KW-7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_001304827.1|refseq:NP_001304829.1|refseq:NP_001121689.1|refseq:NP_066967.3|refseq:NP_150091.2|dip:DIP-46656N|ensembl:ENSG00000164985(gene)|ensembl:ENST00000380733(transcript)|ensembl:ENST00000380738(transcript)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009408"(response to heat)|go:"GO:0034399"(nuclear periphery)|go:"GO:0035327"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0097100"(supercoiled DNA binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000313(PWWP)|interpro:IPR021567|interpro:IPR035441|interpro:IPR035496|interpro:IPR036218|mint:O75475|rcsb pdb:1Z9E|rcsb pdb:2B4J|rcsb pdb:2M16|rcsb pdb:2MSR|rcsb pdb:2MTN|rcsb pdb:2N3A|rcsb pdb:3F9K|rcsb pdb:3HPG|rcsb pdb:3HPH|rcsb pdb:3U88|rcsb pdb:3ZEH|rcsb pdb:4FU6|rcsb pdb:5N88|rcsb pdb:5OYM|rcsb pdb:5YI9|rcsb pdb:6EMO|rcsb pdb:6EMP|rcsb pdb:6EMQ|rcsb pdb:6EMR|rcsb pdb:6S01|rcsb pdb:6TRJ|rcsb pdb:6TVM|rcsb pdb:6Z2Y|reactome:R-HSA-162592|reactome:R-HSA-164843|reactome:R-HSA-175567|reactome:R-HSA-177539|reactome:R-HSA-180689|reactome:R-HSA-180910 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:MRtOw4kH/FxVku25dO5RQiNTjDA9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P06576 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-356231|ensembl:ENSP00000262030|uniprotkb:Q14283|uniprotkb:A8K4X0|intact:EBI-2322803 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:atpb_human(display_long)|uniprotkb:ATP5F1B(gene name)|psi-mi:ATP5F1B(display_short)|uniprotkb:ATP synthase F1 subunit beta(gene name synonym)|uniprotkb:ATP5B(gene name synonym)|uniprotkb:ATPMB(gene name synonym)|uniprotkb:ATPSB(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N ensembl:ENSG00000110955(gene)|ensembl:ENST00000262030(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005754"(mitochondrial proton-transporting ATP synthase, catalytic core)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR000194(ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004100(ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal)|interpro:IPR005722(ATPase, F1 complex, beta subunit)|interpro:IPR020003|interpro:IPR024034|interpro:IPR027417|interpro:IPR036121|mint:P06576|reactome:R-HSA-1268020|reactome:R-HSA-163210|reactome:R-HSA-2151201|reactome:R-HSA-8949613|go:"GO:0070062"(extracellular exosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042288"(MHC class I protein binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045259"(proton-transporting ATP synthase complex)|go:"GO:0045261"("proton-transporting ATP synthase complex, catalytic core F(1)")|go:"GO:0046933"(proton-transporting ATP synthase activity, rotational mechanism)|go:"GO:0046961"(proton-transporting ATPase activity, rotational mechanism)|go:"GO:0051453"(regulation of intracellular pH)|refseq:NP_001677.2 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:oLPUvG1tQkkzxzeAG6R0ZkZF+eg9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P09651 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-352662|uniprotkb:Q3MIB7|uniprotkb:Q6PJZ7|ensembl:ENSP00000341826|ensembl:ENSP00000503610|uniprotkb:A8K4Z8|intact:EBI-2556572 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:roa1_human(display_long)|uniprotkb:HNRNPA1(gene name)|psi-mi:HNRNPA1(display_short)|uniprotkb:HNRPA1(gene name synonym)|uniprotkb:Helix-destabilizing protein(gene name synonym)|uniprotkb:Single-strand RNA-binding protein(gene name synonym)|uniprotkb:hnRNP core protein A1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_002127.1|refseq:NP_112420.1|ensembl:ENSG00000135486(gene)|ensembl:ENST00000340913(transcript)|ensembl:ENST00000677210(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|rcsb pdb:2LYV|rcsb pdb:2UP1|rcsb pdb:4YOE|rcsb pdb:5MPG|rcsb pdb:5MPL|rcsb pdb:5ZGD|rcsb pdb:5ZGL|rcsb pdb:6BXX|rcsb pdb:6DCL|rcsb pdb:6J60|rcsb pdb:7BX7|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035198"(miRNA binding)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051168"(nuclear export)|go:"GO:0051170"(import into nucleus)|go:"GO:0061752"(telomeric repeat-containing RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1903936"(cellular response to sodium arsenite)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021662|interpro:IPR034803|interpro:IPR034845|interpro:IPR035979|mint:P09651|rcsb pdb:1HA1|rcsb pdb:1L3K|rcsb pdb:1PGZ|rcsb pdb:1PO6|rcsb pdb:1U1K|rcsb pdb:1U1L|rcsb pdb:1U1M|rcsb pdb:1U1N|rcsb pdb:1U1O|rcsb pdb:1U1P|rcsb pdb:1U1Q|rcsb pdb:1U1R|rcsb pdb:1UP1|rcsb pdb:2H4M|refseq:XP_005268883.1|dip:DIP-29338N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:ECXjsLRVtNc/aOw90tEFxowHc6c9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P62258 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335|ensembl:ENSP00000487356 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_006752.1|dip:DIP-36676N|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|ensembl:ENSG00000108953(gene)|ensembl:ENSG00000274474(gene)|ensembl:ENST00000264335(transcript)|ensembl:ENST00000627231(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003064"(regulation of heart rate by hormone)|go:"GO:0003723"(RNA binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|reactome:R-HSA-111447 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P07355 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8|ensembl:ENSP00000379342|ensembl:ENSP00000387545|ensembl:ENSP00000411352|ensembl:ENSP00000452858|ensembl:ENSP00000452895|ensembl:ENSP00000452981|ensembl:ENSP00000453694|ensembl:ENSP00000453859|ensembl:ENSP00000503447|ensembl:ENSP00000503757|ensembl:ENSP00000503855|ensembl:ENSP00000504035|ensembl:ENSP00000504164 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|refseq:XP_016877579.1|refseq:XP_016877580.1|ensembl:ENSG00000182718(gene)|ensembl:ENST00000396024(transcript)|ensembl:ENST00000421017(transcript)|ensembl:ENST00000451270(transcript)|ensembl:ENST00000557906(transcript)|ensembl:ENST00000558558(transcript)|ensembl:ENST00000559818(transcript)|ensembl:ENST00000559956(transcript)|ensembl:ENST00000560468(transcript)|ensembl:ENST00000677968(transcript)|ensembl:ENST00000678061(transcript)|ensembl:ENST00000678450(transcript)|ensembl:ENST00000678870(transcript)|ensembl:ENST00000679109(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0005509"(calcium ion binding)|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|go:"GO:0097066"(response to thyroid hormone) - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P61981 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-359832|uniprotkb:O70457|uniprotkb:P35214|uniprotkb:Q6FH52|uniprotkb:Q9UDP2|uniprotkb:Q9UN99|ensembl:ENSP00000306330 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:1433g_human(display_long)|uniprotkb:YWHAG(gene name)|psi-mi:YWHAG(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_036611.2|ensembl:ENSG00000170027(gene)|ensembl:ENST00000307630(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006605"(protein targeting)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0042802"(identical protein binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P61981|rcsb pdb:2B05|rcsb pdb:3UZD|rcsb pdb:4E2E|rcsb pdb:4J6S|rcsb pdb:4O46|rcsb pdb:5D3E|rcsb pdb:6A5S|rcsb pdb:6BYJ|rcsb pdb:6BYL|rcsb pdb:6BZD|rcsb pdb:6FEL|rcsb pdb:6GKF|rcsb pdb:6GKG|rcsb pdb:6S9K|rcsb pdb:6SAD|rcsb pdb:6Y4K|rcsb pdb:6Y6B|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-9614399|dip:DIP-33406N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:u1cd71h0RPgTOEMrQVhOelsxWnM9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P06753 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-355607|uniprotkb:P12324|uniprotkb:Q969Q2|uniprotkb:Q9NQH8|uniprotkb:Q5VU71|uniprotkb:Q2QD06|uniprotkb:D3DV71|ensembl:ENSP00000498577|intact:EBI-11063811|uniprotkb:Q5VU66|uniprotkb:Q5VU72|intact:EBI-4289841|uniprotkb:Q5VU58|uniprotkb:Q5VU63|uniprotkb:Q8TCG3 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:tpm3_human(display_long)|uniprotkb:TPM3(gene name)|psi-mi:TPM3(display_short)|uniprotkb:Tropomyosin-3(gene name synonym)|uniprotkb:Gamma-tropomyosin(gene name synonym)|uniprotkb:Tropomyosin-5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_001265120.1|refseq:NP_001036816.1|refseq:NP_001036817.1|refseq:NP_689476.2|refseq:NP_705935.1|ensembl:ENSG00000143549(gene)|ensembl:ENST00000651641(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005862"(muscle thin filament tropomyosin)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000533(Tropomyosin)|mint:P06753|rcsb pdb:6OTN|reactome:R-HSA-390522|reactome:R-HSA-445355|reactome:R-HSA-9013424|refseq:NP_001036818.1|refseq:NP_001265118.1 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:vHELhEyfZxpK8zHMEveODiYBZmM9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:Q01105 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P12277 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-357706|uniprotkb:Q2LE07|uniprotkb:A8K236|uniprotkb:B2R5R4|uniprotkb:Q6FG40|uniprotkb:Q9UC66|ensembl:ENSP00000299198 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:kcrb_human(display_long)|uniprotkb:CKB(gene name)|psi-mi:CKB(display_short)|uniprotkb:CKBB(gene name synonym)|uniprotkb:Creatine kinase B chain(gene name synonym)|uniprotkb:Brain creatine kinase(gene name synonym)|uniprotkb:Creatine phosphokinase B-type(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_001814.2|go:"GO:0005829"(cytosol)|ensembl:ENSG00000166165(gene)|ensembl:ENST00000348956(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0016301"(kinase activity)|go:"GO:0021549"(cerebellum development)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:P12277|rcsb pdb:3B6R|rcsb pdb:3DRB|rcsb pdb:3DRE|rcsb pdb:6V9H|go:"GO:0021762"(substantia nigra development)|go:"GO:0030425"(dendrite)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046314"(phosphocreatine biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|reactome:R-HSA-71288|reactome:R-HSA-9696264|dip:DIP-52968N - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:WLRnU8sRUfJQoaPY0edGi9xiR+g9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P06733 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:RmP7cr55H8ylcgBOEyivwljIE+09606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P40926 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-721232|uniprotkb:O43682|uniprotkb:B4DE44|uniprotkb:E9PDB2|uniprotkb:A8K414|uniprotkb:B2RE78|ensembl:ENSP00000327070 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:mdhm_human(display_long)|uniprotkb:MDH2(gene name)|psi-mi:MDH2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_005909.2|refseq:NP_001269332.1|refseq:NP_001269333.1|ensembl:ENSG00000146701(gene)|ensembl:ENST00000315758(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0006108"(malate metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0009060"(aerobic respiration)|go:"GO:0016020"(membrane)|go:"GO:0030060"(L-malate dehydrogenase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0046554"("malate dehydrogenase (NADP+) activity")|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001252(Malate dehydrogenase, active site)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR010097(Malate dehydrogenase, NAD-dependent, eukaryotes and gamma proteobacteria)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR022383|interpro:IPR036291|mint:P40926|rcsb pdb:2DFD|rcsb pdb:4WLE|rcsb pdb:4WLF|rcsb pdb:4WLN|rcsb pdb:4WLO|rcsb pdb:4WLU|rcsb pdb:4WLV|reactome:R-HSA-70263|reactome:R-HSA-71403 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:Ur2aO+2M7e/ftD8RlhPMHBc8/JU9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P0CG47 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-413034|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:Q29120|uniprotkb:Q6LBL4|uniprotkb:Q6LDU5|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9BWD6|uniprotkb:Q9BX98|uniprotkb:Q9UEF2|uniprotkb:Q9UEG1|uniprotkb:Q9UEK8|uniprotkb:Q9UPK7|uniprotkb:P62988|ensembl:ENSP00000304697|ensembl:ENSP00000379178|ensembl:ENSP00000379180|ensembl:ENSP00000478771 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:ubb_human(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_061828.1|refseq:NP_001268645.1|refseq:NP_001268646.1|refseq:NP_001268647.1|refseq:NP_001268648.1|refseq:NP_001268649.1|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG47|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060613"(fat pad development)|rcsb pdb:2KHW|rcsb pdb:2MBB|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:2MRO|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|rcsb pdb:2MSG|go:"GO:1901214"(regulation of neuron death)|rcsb pdb:2N13|rcsb pdb:4UEL|rcsb pdb:4UF6|rcsb pdb:4WHV|rcsb pdb:4WLR|rcsb pdb:4WUR|rcsb pdb:4XOF|rcsb pdb:4ZFR|rcsb pdb:4ZFT|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|rcsb pdb:4ZPZ|rcsb pdb:4ZUX|rcsb pdb:5BNB|rcsb pdb:5CAW|rcsb pdb:5CRA|rcsb pdb:5CVM|rcsb pdb:5CVN|rcsb pdb:5CVO|interpro:IPR000626(Ubiquitin)|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5DFL|rcsb pdb:5DK8|rcsb pdb:5E6J|rcsb pdb:5EDV|rcsb pdb:5EMZ|rcsb pdb:5EYA|rcsb pdb:5GJQ|rcsb pdb:5GO7|rcsb pdb:5GO8|rcsb pdb:5GOB|rcsb pdb:5GOC|rcsb pdb:5GOD|rcsb pdb:5GOG|rcsb pdb:5GOH|rcsb pdb:5GOI|rcsb pdb:5GOJ|rcsb pdb:5GOK|rcsb pdb:5H7S|rcsb pdb:5IBK|rcsb pdb:5IFR|rcsb pdb:5JBY|rcsb pdb:5JG6|rcsb pdb:5JP3|rcsb pdb:5JTJ|rcsb pdb:5JTV|rcsb pdb:5K9P|rcsb pdb:5KGF|rcsb pdb:5KHY|rcsb pdb:5KYC|rcsb pdb:5KYD|rcsb pdb:5KYE|rcsb pdb:5KYF|rcsb pdb:5L8H|rcsb pdb:5L8W|rcsb pdb:5L9T|rcsb pdb:5LN1|rcsb pdb:5LRV|rcsb pdb:5LRW|rcsb pdb:5LRX|rcsb pdb:5M93|rcsb pdb:5MNJ|rcsb pdb:5N2W|rcsb pdb:5N38|rcsb pdb:5NL5|rcsb pdb:5NLJ|rcsb pdb:5NVG|rcsb pdb:5O44|rcsb pdb:5O6T|rcsb pdb:5OHK|rcsb pdb:5OHL|rcsb pdb:5OHN|rcsb pdb:5OHP|rcsb pdb:5TOF|rcsb pdb:5TOG|rcsb pdb:5TUT|rcsb pdb:5TXK|rcsb pdb:5UJL|rcsb pdb:5UJN|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5V1Y|rcsb pdb:5V1Z|rcsb pdb:5VEY|rcsb pdb:5VF0|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5VZM|rcsb pdb:5VZW|rcsb pdb:5W46|rcsb pdb:5WFI|rcsb pdb:5X3M|rcsb pdb:5X3N|rcsb pdb:5X3O|rcsb pdb:5XBO|rcsb pdb:5XDP|rcsb pdb:5XK4|rcsb pdb:5XK5|rcsb pdb:5XPK|rcsb pdb:5YDR|rcsb pdb:5YIJ|rcsb pdb:5YIK|rcsb pdb:5YMY|rcsb pdb:5YT6|rcsb pdb:5ZBU|rcsb pdb:5ZD0|rcsb pdb:6ASR|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6CP2|rcsb pdb:6DGF|rcsb pdb:6EI1|rcsb pdb:6FDK|rcsb pdb:6FGE|rcsb pdb:6FTX|rcsb pdb:6FX4|rcsb pdb:6FYH|rcsb pdb:6GLC|rcsb pdb:6GZS|rcsb pdb:6H4H|rcsb pdb:6HEI|rcsb pdb:6HEK|rcsb pdb:6IF1|rcsb pdb:6ISU|rcsb pdb:6JB6|rcsb pdb:6JB7|rcsb pdb:6JMA|rcsb pdb:6K4I|rcsb pdb:6K9P|rcsb pdb:6KOW|rcsb pdb:6KOX|rcsb pdb:6LP2|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6N13|rcsb pdb:6NJ9|rcsb pdb:6NJG|rcsb pdb:6O96|rcsb pdb:6OAM|rcsb pdb:6PGV|rcsb pdb:6PZV|rcsb pdb:6QF8|rcsb pdb:6QK9|rcsb pdb:6QML|rcsb pdb:6TBM|rcsb pdb:6UH5|rcsb pdb:6XAA|rcsb pdb:7AY2|rcsb pdb:7BBD|rcsb pdb:7CAP|rcsb pdb:7JMS|rcsb pdb:7LYC|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|reactome:R-HSA-1253288|reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-162588|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-168928|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174184|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-211733|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2173788|reactome:R-HSA-2173791|reactome:R-HSA-174178|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2467813|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-349425|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69231|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-983168|reactome:R-HSA-8852276|reactome:R-HSA-8941858|reactome:R-HSA-8854050|reactome:R-HSA-8856825|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-8856828|reactome:R-HSA-8951664|reactome:R-HSA-8863795|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9683683|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-975163|reactome:R-HSA-977225|ensembl:ENSG00000170315(gene)|ensembl:ENST00000302182(transcript)|ensembl:ENST00000395837(transcript)|ensembl:ENST00000395839(transcript)|ensembl:ENST00000614404(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031386"(protein tag)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body) - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:X2Y1hzv2uGZd9FObQD2Qq3SECRo9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P56537 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-372243|uniprotkb:Q6IBN8|uniprotkb:Q96TD5|uniprotkb:B7ZBG9|ensembl:ENSP00000363559|ensembl:ENSP00000363574|ensembl:ENSP00000502429 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:if6_human(display_long)|uniprotkb:EIF6(gene name)|psi-mi:EIF6(display_short)|uniprotkb:ITGB4BP(gene name synonym)|uniprotkb:OK/SW-cl.27(orf name)|uniprotkb:B4 integrin interactor(gene name synonym)|uniprotkb:CAB(gene name synonym)|uniprotkb:"p27(BBP)"(gene name synonym)|uniprotkb:"B(2)GCN homolog"(gene name synonym)|uniprotkb:EIF3A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_002203.1|refseq:NP_852131.1|refseq:NP_852133.1|refseq:NP_001254739.1|ensembl:ENSG00000242372(gene)|ensembl:ENST00000374436(transcript)|ensembl:ENST00000374450(transcript)|ensembl:ENST00000675032(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005638"(lamin filament)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0032868"(response to insulin)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0042304"(regulation of fatty acid biosynthetic process)|go:"GO:0043022"(ribosome binding)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902626"(assembly of large subunit precursor of preribosome)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR002769(Translation initiation factor IF6)|mint:P56537|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:A0pOylQptNBlSiBKiZre7INejF49606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:Q9NZT1 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-1051681|uniprotkb:Q8IXU8|uniprotkb:Q5SQI3|ensembl:ENSP00000369689 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:call5_human(display_long)|uniprotkb:Calmodulin-like skin protein(gene name synonym)|uniprotkb:CALML5(gene name)|psi-mi:CALML5(display_short)|uniprotkb:CLSP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_059118.2|ensembl:ENST00000380332(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007165"(signal transduction)|go:"GO:0008544"(epidermis development)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q9NZT1|rcsb pdb:2B1U|reactome:R-HSA-6798695|ensembl:ENSG00000178372(gene) - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:uPD/avsoqpiogqHCK5TGJQwvCX89606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P39687 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-359234|uniprotkb:Q53FK4|uniprotkb:Q5J8L8|uniprotkb:Q7M4N6|uniprotkb:B2R6T4|ensembl:ENSP00000417864 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:an32a_human(display_long)|uniprotkb:ANP32A(gene name)|psi-mi:ANP32A(display_short)|uniprotkb:LANP(gene name synonym)|uniprotkb:PHAP1(gene name synonym)|uniprotkb:C15orf1(gene name synonym)|uniprotkb:MAPM(gene name synonym)|uniprotkb:Potent heat-stable protein phosphatase 2A inhibitor I1PP2A(gene name synonym)|uniprotkb:Acidic nuclear phosphoprotein pp32(gene name synonym)|uniprotkb:Leucine-rich acidic nuclear protein(gene name synonym)|uniprotkb:Putative HLA-DR-associated protein I(gene name synonym)|uniprotkb:Mapmodulin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_006296.1|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR032675|mint:P39687|rcsb pdb:2JE0|rcsb pdb:2JE1|rcsb pdb:4XOS|rcsb pdb:6XZQ|reactome:R-HSA-450520|ensembl:ENSG00000140350(gene)|ensembl:ENST00000465139(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm) - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:uyR/0ZiQuJsE2V1LbRJQiLs+IH49606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:Q9HCY8 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-751842|uniprotkb:Q5RHT0|ensembl:ENSP00000340463|ensembl:ENSP00000357690|ensembl:ENSP00000357691|ensembl:ENSP00000420296 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:s10ae_human(display_long)|uniprotkb:S100 calcium-binding protein A14(gene name synonym)|uniprotkb:S100A14(gene name)|psi-mi:S100A14(display_short)|uniprotkb:S100A15(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_065723.1|refseq:XP_005245419.1|refseq:XP_016857364.1|ensembl:ENSG00000189334(gene)|ensembl:ENST00000344616(transcript)|ensembl:ENST00000368701(transcript)|ensembl:ENST00000368702(transcript)|ensembl:ENST00000476873(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0006915"(apoptotic process)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0042379"(chemokine receptor binding)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071624"(positive regulation of granulocyte chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028493|mint:Q9HCY8|rcsb pdb:2M0R - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:8XSIQKZSb+jAmTmawRUTHjcGwb49606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P31151 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-357520|uniprotkb:Q6FGE3|uniprotkb:Q5SY67|uniprotkb:Q9H1E2|ensembl:ENSP00000357711|ensembl:ENSP00000357712 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:s10a7_human(display_long)|uniprotkb:S100A7(gene name)|psi-mi:S100A7(display_short)|uniprotkb:PSOR1(gene name synonym)|uniprotkb:S100A7C(gene name synonym)|uniprotkb:S100 calcium-binding protein A7(gene name synonym)|uniprotkb:Psoriasin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N ensembl:ENSG00000143556(gene)|ensembl:ENST00000368722(transcript)|ensembl:ENST00000368723(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001525"(angiogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008544"(epidermis development)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045087"(innate immune response)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051238"(sequestering of metal ion)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071624"(positive regulation of granulocyte chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028477|interpro:IPR034325|mint:P31151|rcsb pdb:1PSR|rcsb pdb:2PSR|rcsb pdb:2WND|rcsb pdb:2WOR|rcsb pdb:2WOS|rcsb pdb:3PSR|rcsb pdb:4AQJ|reactome:R-HSA-6798695|reactome:R-HSA-6799990|refseq:NP_002954.2 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:/v8+XQ7rCMTYzq9k/KqjcSm/G0A9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:Q04917 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-306940|ensembl:ENSP00000248975|intact:EBI-11759595 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:1433f_human(display_long)|uniprotkb:YWHAH(gene name)|psi-mi:YWHAH(display_short)|uniprotkb:YWHA1(gene name synonym)|uniprotkb:Protein AS1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0050774"(negative regulation of dendrite morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086010"(membrane depolarization during action potential)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:Q04917|rcsb pdb:2C63|rcsb pdb:2C74|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|ensembl:ENSG00000128245(gene)|ensembl:ENST00000248975(transcript)|go:"GO:0002028"(regulation of sodium ion transport)|go:"GO:0003779"(actin binding)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006713"(glucocorticoid catabolic process)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0014704"(intercalated disc)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|refseq:NP_003396.1|dip:DIP-27566N - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:VhFYPSsW3IRC388FTlmwwN37HnU9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P60174 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-717475|uniprotkb:D3DUS9|uniprotkb:P00938|uniprotkb:Q6IS07|uniprotkb:Q8WWD0|uniprotkb:Q96AG5|uniprotkb:Q6FHP9|uniprotkb:B7Z5D8|ensembl:ENSP00000379933 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:tpis_human(display_long)|uniprotkb:Triose-phosphate isomerase(gene name synonym)|uniprotkb:TPI1(gene name)|psi-mi:TPI1(display_short)|uniprotkb:TPI(gene name synonym)|uniprotkb:Methylglyoxal synthase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_000356.1|refseq:NP_001152759.1|refseq:NP_001244955.1|ensembl:ENSG00000111669(gene)|ensembl:ENST00000396705(transcript)|go:"GO:0004807"(triose-phosphate isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0008929"(methylglyoxal synthase activity)|go:"GO:0019242"(methylglyoxal biosynthetic process)|go:"GO:0019563"(glycerol catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046166"(glyceraldehyde-3-phosphate biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000652(Triosephosphate isomerase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR020861|interpro:IPR022896|interpro:IPR035990|mint:P60174|rcsb pdb:1HTI|rcsb pdb:1KLG|rcsb pdb:1KLU|rcsb pdb:1WYI|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2JK2|rcsb pdb:2VOM|rcsb pdb:4BR1|rcsb pdb:4E41|rcsb pdb:4POC|rcsb pdb:4POD|rcsb pdb:4UNK|rcsb pdb:4UNL|rcsb pdb:4ZVJ|rcsb pdb:6C2G|rcsb pdb:6D43|rcsb pdb:6NLH|rcsb pdb:6UP1|rcsb pdb:6UP5|rcsb pdb:6UP8|rcsb pdb:6UPF|reactome:R-HSA-70171|reactome:R-HSA-70263 - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:FaLt6wGI1Bz2Z81gX35p7sOiMbE9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:Q00688 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-1044081|uniprotkb:Q14317|ensembl:ENSP00000216330|ensembl:ENSP00000379374|uniprotkb:B2R4Q9 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:fkbp3_human(display_long)|uniprotkb:FKBP3(gene name)|psi-mi:FKBP3(display_short)|uniprotkb:FKBP25(gene name synonym)|uniprotkb:FK506-binding protein 3(gene name synonym)|uniprotkb:Rotamase(gene name synonym)|uniprotkb:Immunophilin FKBP25(gene name synonym)|uniprotkb:Rapamycin-selective 25 kDa immunophilin(gene name synonym)|uniprotkb:25 kDa FK506-binding protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_002004.1|ensembl:ENSG00000100442(gene)|ensembl:ENST00000216330(transcript)|ensembl:ENST00000396062(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005528"(FK506 binding)|go:"GO:0005634"(nucleus)|go:"GO:0038023"(signaling receptor activity)|interpro:IPR041200|interpro:IPR043368|mint:Q00688|rcsb pdb:1PBK|rcsb pdb:2KFV|rcsb pdb:2MPH|rcsb pdb:5D75|rcsb pdb:5GPG|interpro:IPR001179(Peptidyl-prolyl cis-trans isomerase, FKBP-type) - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:xU5FDlTZzy8veAtOaoLtQMeBsr09606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:Q13867 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-718504|uniprotkb:Q53F86|uniprotkb:Q9UER9|uniprotkb:B2R796|ensembl:ENSP00000261714 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:blmh_human(display_long)|uniprotkb:BLMH(gene name)|psi-mi:BLMH(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_000377.1|ensembl:ENSG00000108578(gene)|ensembl:ENST00000261714(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043418"(homocysteine catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR004134(Peptidase C1B, bleomycin hydrolase)|interpro:IPR038765|mint:Q13867|rcsb pdb:1CB5|rcsb pdb:2CB5|reactome:R-HSA-983168 - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:THDv63DC81eQzFvmyWs1rlCBMyk9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P31946 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-359815|uniprotkb:A8K9K2|uniprotkb:E1P616|ensembl:ENSP00000300161|ensembl:ENSP00000361930 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:1433b_human(display_long)|uniprotkb:YWHAB(gene name)|psi-mi:YWHAB(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Protein 1054(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_003395.1|refseq:NP_647539.1|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P31946|rcsb pdb:2BQ0|rcsb pdb:2C23|rcsb pdb:4DNK|rcsb pdb:5N10|rcsb pdb:6A5Q|rcsb pdb:6BYK|rcsb pdb:6GN0|rcsb pdb:6GN8|rcsb pdb:6GNJ|rcsb pdb:6GNK|rcsb pdb:6GNN|rcsb pdb:6HEP|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-170968|reactome:R-HSA-170984|reactome:R-HSA-2028269|reactome:R-HSA-392517|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|ensembl:ENSG00000166913(gene)|ensembl:ENST00000353703(transcript)|ensembl:ENST00000372839(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:XP_016883528.1|dip:DIP-743N - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:rp43CodPzsPadWEPtbnpKFAVIIU9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P30048 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-748336|intact:EBI-10975142|uniprotkb:P35690|uniprotkb:Q0D2H1|uniprotkb:Q13776|uniprotkb:Q5T5V2|uniprotkb:Q96HK4|uniprotkb:B2R7Z0|uniprotkb:D3DRC9|uniprotkb:E9PH29|ensembl:ENSP00000298510 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:prdx3_human(display_long)|uniprotkb:Peroxiredoxin-3(gene name synonym)|uniprotkb:Peroxiredoxin III(gene name synonym)|uniprotkb:Antioxidant protein 1(gene name synonym)|uniprotkb:Protein MER5 homolog(gene name synonym)|uniprotkb:HBC189(gene name synonym)|uniprotkb:PRDX3(gene name)|psi-mi:PRDX3(display_short)|uniprotkb:AOP1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_001289201.1|refseq:NP_006784.1|ensembl:ENSG00000165672(gene)|ensembl:ENST00000298510(transcript)|go:"GO:0001893"(maternal placenta development)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0008785"(alkyl hydroperoxide reductase activity)|go:"GO:0018171"(peptidyl-cysteine oxidation)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033673"(negative regulation of kinase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR036249|mint:P30048|rcsb pdb:5JCG|rcsb pdb:5UCX|reactome:R-HSA-3299685|go:"GO:0005769"(early endosome)|dip:DIP-33600N - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:+J/zV8u0jGCSzTGXafxgecTv/149606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P14625 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-359129|uniprotkb:Q96A97|ensembl:ENSP00000299767 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:enpl_human(display_long)|uniprotkb:HSP90B1(gene name)|psi-mi:HSP90B1(display_short)|uniprotkb:TRA1(gene name synonym)|uniprotkb:Heat shock protein 90 kDa beta member 1(gene name synonym)|uniprotkb:94 kDa glucose-regulated protein(gene name synonym)|uniprotkb:GRP94(gene name synonym)|uniprotkb:gp96 homolog(gene name synonym)|uniprotkb:Tumor rejection antigen 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_003290.1|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051208"(sequestering of calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071682"(endocytic vesicle lumen)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P14625|rcsb pdb:4NH9|reactome:R-HSA-1679131|reactome:R-HSA-3000480|reactome:R-HSA-381183|reactome:R-HSA-381426|reactome:R-HSA-6785807|reactome:R-HSA-8957275|ensembl:ENSG00000166598(gene)|ensembl:ENST00000299767(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030496"(midbody)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031247"(actin rod assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|dip:DIP-36060N - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:m5CdlplqVyMUWYe75aKDuMzztMY9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P14314 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-716953|uniprotkb:Q96BU9|uniprotkb:Q96D06|uniprotkb:Q9P0W9|uniprotkb:A8K318|ensembl:ENSP00000465461 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:glu2b_human(display_long)|uniprotkb:Glucosidase II subunit beta(gene name synonym)|uniprotkb:Protein kinase C substrate 60.1 kDa protein heavy chain(gene name synonym)|uniprotkb:80K-H protein(gene name synonym)|uniprotkb:PRKCSH(gene name)|psi-mi:PRKCSH(display_short)|uniprotkb:G19P1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_001001329.1|refseq:NP_002734.2|refseq:XP_011526433.1|refseq:XP_011526434.1|refseq:NP_001276031.1|ensembl:ENSG00000130175(gene)|ensembl:ENST00000589838(transcript)|go:"GO:0001889"(liver development)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006491"(N-glycan processing)|go:"GO:0017177"(glucosidase II complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR002172(Low density lipoprotein-receptor, class A, cysteine-rich)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR028146|interpro:IPR036055|interpro:IPR036607|interpro:IPR039794|interpro:IPR044865|mint:P14314|reactome:R-HSA-381426|reactome:R-HSA-532668|reactome:R-HSA-879415|reactome:R-HSA-8957275|reactome:R-HSA-901042|reactome:R-HSA-9683686|reactome:R-HSA-9694548|refseq:XP_016882466.1 - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:hs2AZthZKK6KVW8Blm1RuZVh1QM9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P26583 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-1057009|uniprotkb:Q5U072|uniprotkb:D3DP37|uniprotkb:B2R4K8|ensembl:ENSP00000296503|ensembl:ENSP00000393448|ensembl:ENSP00000404912 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:hmgb2_human(display_long)|uniprotkb:HMGB2(gene name)|psi-mi:HMGB2(display_short)|uniprotkb:HMG2(gene name synonym)|uniprotkb:High mobility group protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_001124160.1|refseq:NP_001124161.1|refseq:NP_002120.1|ensembl:ENSG00000164104(gene)|ensembl:ENST00000296503(transcript)|ensembl:ENST00000438704(transcript)|ensembl:ENST00000446922(transcript)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006265"(DNA topological change)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006325"(chromatin organization)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0008584"(male gonad development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032075"(positive regulation of nuclease activity)|go:"GO:0032392"(DNA geometric change)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033151"("V(D)J recombination")|go:"GO:0042056"(chemoattractant activity)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0044378"(non-sequence-specific DNA binding, bending)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045654"(positive regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0097100"(supercoiled DNA binding)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR017967|interpro:IPR036910|mint:P26583|reactome:R-HSA-140342 - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:ACzaSeIwT3vM4ZgpCSSlzA6nd4U9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:Q99497 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-1164361|uniprotkb:O14805|uniprotkb:Q6DR95|uniprotkb:Q7LFU2|uniprotkb:B2R4Z1|ensembl:ENSP00000340278|ensembl:ENSP00000366708|ensembl:ENSP00000366711|ensembl:ENSP00000418770|ensembl:ENSP00000465404 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:park7_human(display_long)|uniprotkb:PARK7(gene name)|psi-mi:PARK7(display_short)|uniprotkb:Oncogene DJ1(gene name synonym)|uniprotkb:Parkinsonism-associated deglycase(gene name synonym)|uniprotkb:Maillard deglycase(gene name synonym)|uniprotkb:Protein DJ-1(gene name synonym)|uniprotkb:Protein/nucleic acid deglycase DJ-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_001116849.1|refseq:NP_009193.2|refseq:XP_005263481.1|go:"GO:0046295"(glycolate biosynthetic process)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050787"(detoxification of mercury ion)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051899"(membrane depolarization)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061727"(methylglyoxal catabolic process to lactate)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070994"(detection of oxidative stress)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098793"(presynapse)|go:"GO:0106044"(guanine deglycation)|go:"GO:0106045"(guanine deglycation, methylglyoxal removal)|go:"GO:0106046"(guanine deglycation, glyoxal removal)|go:"GO:0110095"(cellular detoxification of aldehyde)|go:"GO:0140041"(cellular detoxification of methylglyoxal)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901671"(positive regulation of superoxide dismutase activity)|go:"GO:1901984"(negative regulation of protein acetylation)|go:"GO:1902177"(positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902903"(regulation of supramolecular fiber organization)|go:"GO:1902958"(positive regulation of mitochondrial electron transport, NADH to ubiquinone)|go:"GO:1903073"(negative regulation of death-inducing signaling complex assembly)|go:"GO:1903094"(negative regulation of protein K48-linked deubiquitination)|go:"GO:1903122"(negative regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1903135"(cupric ion binding)|go:"GO:1903136"(cuprous ion binding)|go:"GO:1903168"(positive regulation of pyrroline-5-carboxylate reductase activity)|go:"GO:1903178"(positive regulation of tyrosine 3-monooxygenase activity)|go:"GO:1903181"(positive regulation of dopamine biosynthetic process)|go:"GO:1903189"(glyoxal metabolic process)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1903200"(positive regulation of L-dopa decarboxylase activity)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|go:"GO:1903208"(negative regulation of hydrogen peroxide-induced neuron death)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903384"(negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1905259"(negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990422"("glyoxalase (glycolic acid-forming) activity")|go:"GO:2000157"(negative regulation of ubiquitin-specific protease activity)|go:"GO:2000277"(positive regulation of oxidative phosphorylation uncoupler activity)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2000825"(positive regulation of androgen receptor activity)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001268"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR002818(ThiJ/PfpI)|interpro:IPR006287(DJ-1)|interpro:IPR029062|go:"GO:1903197"(positive regulation of L-dopa biosynthetic process)|rcsb pdb:3B36|rcsb pdb:3B38|rcsb pdb:3B3A|rcsb pdb:3BWE|rcsb pdb:3CY6|rcsb pdb:3CYF|rcsb pdb:3CZ9|rcsb pdb:3CZA|rcsb pdb:3EZG|mint:Q99497|rcsb pdb:1J42|rcsb pdb:1P5F|rcsb pdb:3F71|rcsb pdb:1PDV|rcsb pdb:1PDW|rcsb pdb:1PE0|rcsb pdb:1Q2U|rcsb pdb:3SF8|rcsb pdb:1SOA|rcsb pdb:1UCF|rcsb pdb:2OR3|rcsb pdb:2R1T|rcsb pdb:2R1U|rcsb pdb:2R1V|rcsb pdb:4BTE|rcsb pdb:2RK3|rcsb pdb:2RK4|rcsb pdb:2RK6|ensembl:ENSG00000116288(gene)|ensembl:ENST00000338639(transcript)|ensembl:ENST00000377488(transcript)|ensembl:ENST00000377491(transcript)|ensembl:ENST00000493678(transcript)|ensembl:ENST00000493373(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002866"(positive regulation of acute inflammatory response to antigenic stimulus)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006281"(DNA repair)|rcsb pdb:4MTC|rcsb pdb:4N0M|rcsb pdb:4N12|rcsb pdb:4OGF|rcsb pdb:4OQ4|rcsb pdb:4P2G|rcsb pdb:4P34|rcsb pdb:4P35|rcsb pdb:4P36|rcsb pdb:4RKW|rcsb pdb:4RKY|rcsb pdb:4S0Z|rcsb pdb:4ZGG|rcsb pdb:5IP5|rcsb pdb:5SY6|rcsb pdb:5SY9|rcsb pdb:5SYA|rcsb pdb:6AF5|rcsb pdb:6AF7|rcsb pdb:6AF9|rcsb pdb:6AFA|rcsb pdb:6AFB|rcsb pdb:6AFC|rcsb pdb:6AFD|rcsb pdb:6AFE|rcsb pdb:6AFF|rcsb pdb:6AFG|rcsb pdb:6AFH|rcsb pdb:6AFI|rcsb pdb:6AFJ|rcsb pdb:6AFL|rcsb pdb:6E5Z|rcsb pdb:6M8Z|rcsb pdb:7C62|reactome:R-HSA-3899300|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9646399|rcsb pdb:4MNT|go:"GO:0006517"(protein deglycosylation)|go:"GO:0006914"(autophagy)|go:"GO:0006954"(inflammatory response)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007338"(single fertilization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009438"(methylglyoxal metabolic process)|go:"GO:0010273"(detoxification of copper ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016532"(superoxide dismutase copper chaperone activity)|go:"GO:0016570"(histone modification)|go:"GO:0016605"(PML body)|go:"GO:0016684"(oxidoreductase activity, acting on peroxide as acceptor)|go:"GO:0019249"(lactate biosynthetic process)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0030424"(axon)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033864"("positive regulation of NAD(P)H oxidase activity")|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0036470"(tyrosine 3-monooxygenase activator activity)|go:"GO:0036471"(cellular response to glyoxal)|go:"GO:0036478"(L-dopa decarboxylase activator activity)|go:"GO:0036524"(protein deglycase activity)|go:"GO:0036526"(peptidyl-cysteine deglycation)|go:"GO:0036527"(peptidyl-arginine deglycation)|go:"GO:0036528"(peptidyl-lysine deglycation)|go:"GO:0036529"(protein deglycation, glyoxal removal)|go:"GO:0036530"(protein deglycation, methylglyoxal removal)|go:"GO:0036531"(glutathione deglycation)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042743"(hydrogen peroxide metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0030073"(insulin secretion)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045340"(mercury ion binding)|dip:DIP-35515N - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:i5ah4UPCf+4cD51ClZNggMFJMDo9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:Q9Y5S9 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-447231|uniprotkb:Q6FHD1|uniprotkb:Q6IQ40|uniprotkb:Q9GZX8|uniprotkb:Q9NZI4|uniprotkb:B3KQI9|intact:EBI-28979675|ensembl:ENSP00000463058|ensembl:ENSP00000488265 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:rbm8a_human(display_long)|uniprotkb:HSPC114(orf name)|uniprotkb:MDS014(orf name)|uniprotkb:RNA-binding motif protein 8A(gene name synonym)|uniprotkb:Ribonucleoprotein RBM8A(gene name synonym)|uniprotkb:RNA-binding protein Y14(gene name synonym)|uniprotkb:Binder of OVCA1-1(gene name synonym)|uniprotkb:RBM8A(gene name)|psi-mi:RBM8A(display_short)|uniprotkb:RBM8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_005096.1|ensembl:ENST00000369307|ensembl:ENSP00000358313|ensembl:ENSP00000463058|ensembl:ENSP00000488265|dip:DIP-33070N|ensembl:ENSG00000265241(gene)|ensembl:ENST00000583313(transcript)|ensembl:ENST00000632555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0030425"(dendrite)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051028"(mRNA transport)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR008111(RNA binding motif protein 8)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033744|interpro:IPR035979|mint:Q9Y5S9|rcsb pdb:1P27|rcsb pdb:2HYI|rcsb pdb:2J0Q|rcsb pdb:2J0S|rcsb pdb:2XB2|rcsb pdb:3EX7|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:6ICZ|rcsb pdb:6QDV|rcsb pdb:7A5P|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9010553|reactome:R-HSA-975957 - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:7WdTcDs4RqjiKDSkHF0fFD8rAb09606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P18669 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-717905|uniprotkb:Q9BWC0|ensembl:ENSP00000359991 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:pgam1_human(display_long)|uniprotkb:Phosphoglycerate mutase isozyme B(gene name synonym)|uniprotkb:BPG-dependent PGAM 1(gene name synonym)|uniprotkb:PGAM1(gene name)|psi-mi:PGAM1(display_short)|uniprotkb:CDABP0006(orf name)|uniprotkb:PGAMA(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_002620.1|ensembl:ENSG00000171314(gene)|ensembl:ENST00000334828(transcript)|go:"GO:0004082"(bisphosphoglycerate mutase activity)|go:"GO:0004619"(phosphoglycerate mutase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006096"(glycolytic process)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043456"(regulation of pentose-phosphate shunt)|go:"GO:0045730"(respiratory burst)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001345(Phosphoglycerate/bisphosphoglycerate mutase)|interpro:IPR005952(Phosphoglycerate mutase 1)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR029033|mint:P18669|rcsb pdb:1LJD|rcsb pdb:1YFK|rcsb pdb:1YJX|rcsb pdb:4GPI|rcsb pdb:4GPZ|rcsb pdb:5Y2I|rcsb pdb:5Y2U|rcsb pdb:5Y35|rcsb pdb:5Y64|rcsb pdb:5Y65|rcsb pdb:5ZRM|rcsb pdb:5ZS8|rcsb pdb:6ISN|reactome:R-HSA-6798695|reactome:R-HSA-70171|reactome:R-HSA-70263 - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:GI6jwRrX08owCyzx8KnRU8QP2rg9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P29401 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-1050560|uniprotkb:Q8TBA3|uniprotkb:Q96HH3|uniprotkb:A8K089|uniprotkb:B4DE31|uniprotkb:E7EPA7|ensembl:ENSP00000405455|ensembl:ENSP00000417773|intact:EBI-11110174 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:tkt_human(display_long)|uniprotkb:TKT(gene name)|psi-mi:TKT(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_001055.1|refseq:NP_001128527.1|refseq:NP_001244957.1|ensembl:ENSG00000163931(gene)|ensembl:ENST00000423525(transcript)|ensembl:ENST00000462138(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004802"(transketolase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0009052"(pentose-phosphate shunt, non-oxidative branch)|go:"GO:0016604"(nuclear body)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0031982"(vesicle)|go:"GO:0040008"(regulation of growth)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046166"(glyceraldehyde-3-phosphate biosynthetic process)|go:"GO:0046390"(ribose phosphate biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005474(Transketolase, N-terminal)|interpro:IPR005475(Transketolase, central region)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR020826|interpro:IPR029061|interpro:IPR033248|mint:P29401|rcsb pdb:3MOS|rcsb pdb:3OOY|rcsb pdb:4KXU|rcsb pdb:4KXV|rcsb pdb:4KXW|rcsb pdb:4KXX|rcsb pdb:4KXY|rcsb pdb:6HA3|rcsb pdb:6HAD|rcsb pdb:6RJB|reactome:R-HSA-163754|reactome:R-HSA-71336|refseq:XP_011532356.1 - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:Z3Ad5GdEd0rFCT9uHv85N+2KAAY9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P14174 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-372712|uniprotkb:A5Z1R8|uniprotkb:B2R4S3|uniprotkb:Q6FHV0|uniprotkb:Q2V4Y5|ensembl:ENSP00000215754|ensembl:ENSP00000482779 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:mif_human(display_long)|uniprotkb:MIF(gene name)|psi-mi:MIF(display_short)|uniprotkb:MMIF(gene name synonym)|uniprotkb:GLIF(gene name synonym)|uniprotkb:Phenylpyruvate tautomerase(gene name synonym)|uniprotkb:Glycosylation-inhibiting factor(gene name synonym)|uniprotkb:L-dopachrome tautomerase(gene name synonym)|uniprotkb:L-dopachrome isomerase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_002406.1|ensembl:ENST00000215754(transcript)|ensembl:ENST00000613839(transcript)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004167"(dopachrome isomerase activity)|go:"GO:0005125"(cytokine activity)|go:"GO:0005126"(cytokine receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|ensembl:ENSG00000276701(gene)|go:"GO:0006954"(inflammatory response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010739"(positive regulation of protein kinase A signaling)|go:"GO:0010760"(negative regulation of macrophage chemotaxis)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031982"(vesicle)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|ensembl:ENSG00000240972(gene)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045087"(innate immune response)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0050178"(phenylpyruvate tautomerase activity)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001398(Macrophage migration inhibitory factor)|interpro:IPR014347(Tautomerase)|interpro:IPR019829|mint:P14174|rcsb pdb:1CGQ|rcsb pdb:1GCZ|rcsb pdb:1GD0|rcsb pdb:1GIF|rcsb pdb:1LJT|rcsb pdb:1MIF|rcsb pdb:1P1G|rcsb pdb:2OOH|rcsb pdb:2OOW|rcsb pdb:2OOZ|rcsb pdb:3B9S|rcsb pdb:3CE4|rcsb pdb:3DJH|rcsb pdb:3DJI|rcsb pdb:3HOF|rcsb pdb:3IJG|rcsb pdb:3IJJ|rcsb pdb:3JSF|rcsb pdb:3JSG|rcsb pdb:3JTU|rcsb pdb:3L5P|rcsb pdb:3L5R|rcsb pdb:3L5S|rcsb pdb:3L5T|rcsb pdb:3L5U|rcsb pdb:3L5V|rcsb pdb:3SMB|rcsb pdb:3SMC|rcsb pdb:3U18|rcsb pdb:3WNR|rcsb pdb:3WNS|rcsb pdb:3WNT|rcsb pdb:4ETG|rcsb pdb:4EUI|rcsb pdb:4EVG|rcsb pdb:4F2K|rcsb pdb:4GRN|rcsb pdb:4GRO|rcsb pdb:4GRP|rcsb pdb:4GRQ|rcsb pdb:4GRR|rcsb pdb:4GRU|rcsb pdb:4GUM|rcsb pdb:4K9G|rcsb pdb:4OSF|rcsb pdb:4OYQ|rcsb pdb:4P01|rcsb pdb:4P0H|rcsb pdb:4PKK|rcsb pdb:4PKZ|rcsb pdb:4PLU|rcsb pdb:4TRF|rcsb pdb:4TRU|rcsb pdb:4WR8|rcsb pdb:4WRB|rcsb pdb:4XX7|rcsb pdb:4XX8|rcsb pdb:4Z15|rcsb pdb:4Z1T|rcsb pdb:4Z1U|rcsb pdb:5B4O|rcsb pdb:5BS9|rcsb pdb:5BSC|rcsb pdb:5BSI|rcsb pdb:5BSJ|rcsb pdb:5EIZ|rcsb pdb:5HVS|rcsb pdb:5HVT|rcsb pdb:5HVV|rcsb pdb:5J7P|rcsb pdb:5J7Q|rcsb pdb:5UMJ|rcsb pdb:5UMK|rcsb pdb:5UZY|rcsb pdb:5V70|rcsb pdb:5V73|rcsb pdb:5XEJ|rcsb pdb:1CA7|rcsb pdb:6B1C|rcsb pdb:6B1K|rcsb pdb:6B2C|rcsb pdb:6BG6|rcsb pdb:6BG7|rcsb pdb:6CB5|rcsb pdb:6CBF|rcsb pdb:6CBG|rcsb pdb:6FVE|rcsb pdb:6FVH|rcsb pdb:6OY8|rcsb pdb:6OYB|rcsb pdb:6OYE|rcsb pdb:6OYG|rcsb pdb:6PEG|reactome:R-HSA-202733|reactome:R-HSA-6798695|reactome:R-HSA-8950505|rcsb pdb:6CBH|dip:DIP-31137N - - comment:"author score: 27" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:Vk+Sfaz5c59y8dKKJ4Qn+7fjwvQ9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P06454 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-2682091|uniprotkb:Q15249|uniprotkb:Q15592|ensembl:ENSP00000344547 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:ptma_human(display_long)|uniprotkb:TMSA(gene name synonym)|uniprotkb:PTMA(gene name)|psi-mi:PTMA(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_001092755.1|refseq:NP_002814.3|ensembl:ENSG00000187514(gene)|ensembl:ENST00000341369(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR004931(Prothymosin/parathymosin)|mint:P06454|rcsb pdb:2L9I|rcsb pdb:2MNQ|dip:DIP-40743N - - comment:"author score: 27" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:scRCSTJyl5e12uNhBR+L4CKQ6Ac9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P17096 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-746843|uniprotkb:P10910|uniprotkb:Q9UKB0|uniprotkb:Q5T6U9|ensembl:ENSP00000308227|ensembl:ENSP00000399888 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:hmga1_human(display_long)|uniprotkb:High mobility group AT-hook protein 1(gene name synonym)|uniprotkb:HMGA1(gene name)|psi-mi:HMGA1(display_short)|uniprotkb:HMGIY(gene name synonym)|uniprotkb:High mobility group protein R(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_002122.1|refseq:NP_665906.1|refseq:NP_665908.1|refseq:NP_665909.1|refseq:NP_665910.1|refseq:NP_665912.1|refseq:NP_001306006.1|refseq:NP_001306007.1|refseq:NP_001306008.1|refseq:NP_001306009.1|refseq:NP_001306010.1|refseq:NP_001306011.1|ensembl:ENSG00000137309(gene)|ensembl:ENST00000311487(transcript)|ensembl:ENST00000447654(transcript)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0019899"(enzyme binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030527"(structural constituent of chromatin)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0035985"(senescence-associated heterochromatin focus)|go:"GO:0035986"(obsolete senescence-associated heterochromatin focus assembly)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0090402"(oncogene-induced cell senescence)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR000116(High mobility group, HMG-I and HMG-Y)|interpro:IPR000637(HMG-I and HMG-Y, DNA-binding)|interpro:IPR017956|interpro:IPR031079|mint:P17096|rcsb pdb:2EZD|rcsb pdb:2EZE|rcsb pdb:2EZF|rcsb pdb:2EZG|reactome:R-HSA-162592|reactome:R-HSA-164843|reactome:R-HSA-175567|reactome:R-HSA-177539|reactome:R-HSA-180689|reactome:R-HSA-180910|reactome:R-HSA-2559584|dip:DIP-29687N - - comment:"author score: 28" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:hhCMZ6CUf3e+PD0RNIauCZ8EThM9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P29966 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-1047781|uniprotkb:E1P560|uniprotkb:Q2LA83|uniprotkb:Q5TDB7|ensembl:ENSP00000478061 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:marcs_human(display_long)|uniprotkb:Protein kinase C substrate, 80 kDa protein, light chain(gene name synonym)|uniprotkb:MARCKS(gene name)|psi-mi:MARCKS(display_short)|uniprotkb:MACS(gene name synonym)|uniprotkb:PRKCSL(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_002347.5|ensembl:ENSG00000277443(gene)|ensembl:ENST00000612661(transcript)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007417"(central nervous system development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032432"(actin filament bundle)|go:"GO:0042585"(germinal vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002101(Myristoylated alanine-rich C-kinase substrate MARCKS)|mint:P29966|reactome:R-HSA-399997 - - comment:"author score: 29" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:28v6sOqwULr0AvfJr7yAal9Yh1g9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:Q13838 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-348622|uniprotkb:B0S8C0|uniprotkb:Q5STB8|uniprotkb:O43496|uniprotkb:Q0EFA1|uniprotkb:Q2L6F9|uniprotkb:Q53GL9|uniprotkb:Q5RJ64|uniprotkb:Q5RJ66|uniprotkb:Q5ST94|uniprotkb:Q5STB4|uniprotkb:Q5STB5|uniprotkb:Q5STB7|uniprotkb:Q5STU4|uniprotkb:Q5STU5|uniprotkb:Q5STU6|uniprotkb:Q5STU8|uniprotkb:Q71V76|ensembl:ENSP00000373000|ensembl:ENSP00000379475|ensembl:ENSP00000383151|ensembl:ENSP00000383152|ensembl:ENSP00000387994|ensembl:ENSP00000388880|ensembl:ENSP00000390999|ensembl:ENSP00000391463|ensembl:ENSP00000393712|ensembl:ENSP00000394160|ensembl:ENSP00000398775|ensembl:ENSP00000399030|ensembl:ENSP00000400326|ensembl:ENSP00000404695|ensembl:ENSP00000405560|ensembl:ENSP00000407419|ensembl:ENSP00000411136|ensembl:ENSP00000411853|ensembl:ENSP00000416269 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:dx39b_human(display_long)|uniprotkb:UAP56(gene name synonym)|uniprotkb:DDX39B(gene name)|psi-mi:DDX39B(display_short)|uniprotkb:DEAD box protein UAP56(gene name synonym)|uniprotkb:56 kDa U2AF65-associated protein(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p47(gene name synonym)|uniprotkb:HLA-B-associated transcript 1 protein(gene name synonym)|uniprotkb:BAT1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_004631.1|refseq:NP_542165.1|ensembl:ENSG00000198563(gene)|ensembl:ENSG00000215425(gene)|ensembl:ENSG00000225073(gene)|ensembl:ENSG00000225859(gene)|ensembl:ENSG00000229496(gene)|ensembl:ENSG00000230624(gene)|ensembl:ENSG00000235439(gene)|ensembl:ENST00000383508(transcript)|ensembl:ENST00000396172(transcript)|ensembl:ENST00000400295(transcript)|ensembl:ENST00000400296(transcript)|ensembl:ENST00000412106(transcript)|ensembl:ENST00000412330(transcript)|ensembl:ENST00000413678(transcript)|ensembl:ENST00000414440(transcript)|ensembl:ENST00000415689(transcript)|ensembl:ENST00000416863(transcript)|ensembl:ENST00000430784(transcript)|ensembl:ENST00000431360(transcript)|ensembl:ENST00000441425(transcript)|ensembl:ENST00000445218(transcript)|ensembl:ENST00000448296(transcript)|ensembl:ENST00000453138(transcript)|ensembl:ENST00000456476(transcript)|ensembl:ENST00000456666(transcript)|ensembl:ENST00000458640(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000346"(transcription export complex)|go:"GO:0001889"(liver development)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0008380"(RNA splicing)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2000002"(negative regulation of DNA damage checkpoint)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q13838|rcsb pdb:1T5I|rcsb pdb:1T6N|rcsb pdb:1XTI|rcsb pdb:1XTJ|rcsb pdb:1XTK|rcsb pdb:7APK|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9013418 - - comment:"author score: 29" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:Cl/rf1oq31fZbLHC2foUXu9MBOE9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:Q13765 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-712216|ensembl:ENSP00000349212|ensembl:ENSP00000377469|ensembl:ENSP00000446801|ensembl:ENSP00000447821|ensembl:ENSP00000503345|uniprotkb:Q3KQV4|uniprotkb:Q53A18|uniprotkb:Q53G46|uniprotkb:A8MTN7|uniprotkb:B2R4P8|uniprotkb:F8VU71 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:naca_human(display_long)|uniprotkb:Alpha-NAC(gene name synonym)|uniprotkb:NACA(gene name)|psi-mi:NACA(display_short)|uniprotkb:HSD48(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N ensembl:ENSG00000196531(gene)|ensembl:ENST00000356769(transcript)|ensembl:ENST00000393891(transcript)|ensembl:ENST00000546392(transcript)|ensembl:ENST00000552540(transcript)|ensembl:ENST00000678066(transcript)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005854"(nascent polypeptide-associated complex)|go:"GO:0006412"(translation)|go:"GO:0010664"(negative regulation of striated muscle cell apoptotic process)|go:"GO:0015031"(protein transport)|go:"GO:0042060"(wound healing)|go:"GO:0048633"(positive regulation of skeletal muscle tissue growth)|go:"GO:0048742"(regulation of skeletal muscle fiber development)|go:"GO:0061384"(heart trabecula morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901227"(negative regulation of transcription from RNA polymerase II promoter involved in heart development)|go:"GO:1901228"(positive regulation of transcription from RNA polymerase II promoter involved in heart development)|go:"GO:2000138"(positive regulation of cell proliferation involved in heart morphogenesis)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR016641(Nascent polypeptide-associated complex, alpha subunit)|interpro:IPR038187|interpro:IPR044034|mint:Q13765|rcsb pdb:3LKX|rcsb pdb:3MCB|rcsb pdb:3MCE|go:"GO:0043403"(skeletal muscle tissue regeneration)|refseq:NP_001106672.1|refseq:NP_001307122.1|refseq:NP_001307123.1|refseq:NP_005585.1|refseq:NP_001106673.1|refseq:NP_001106674.2|dip:DIP-43878N - - comment:"author score: 29" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:l8QKB8mfSwvDDSSObGLQ7i1LgWo9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P30086 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-716384|uniprotkb:B2R4S1|ensembl:ENSP00000261313 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:pebp1_human(display_long)|uniprotkb:Prostatic-binding protein(gene name synonym)|uniprotkb:HCNPpp(gene name synonym)|uniprotkb:Neuropolypeptide h3(gene name synonym)|uniprotkb:Raf kinase inhibitor protein(gene name synonym)|uniprotkb:PEBP1(gene name)|psi-mi:PEBP1(display_short)|uniprotkb:PEBP(gene name synonym)|uniprotkb:PBP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_002558.1|ensembl:ENSG00000089220(gene)|ensembl:ENST00000261313(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001858(Phosphatidylethanolamine-binding, conserved site)|interpro:IPR008914(Phosphatidylethanolamine-binding protein PEBP)|interpro:IPR035810|interpro:IPR036610|mint:P30086|rcsb pdb:1BD9|rcsb pdb:1BEH|rcsb pdb:2L7W|rcsb pdb:2QYQ|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|dip:DIP-44269N - - comment:"author score: 30" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:6NY/YmyO5c8tNYfXtujwvP2chIc9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:Q92688 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-762428|uniprotkb:O00655|uniprotkb:P78458|uniprotkb:P78459|uniprotkb:B2R9C7|ensembl:ENSP00000345848 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:an32b_human(display_long)|uniprotkb:Acidic protein rich in leucines(gene name synonym)|uniprotkb:Silver-stainable protein SSP29(gene name synonym)|uniprotkb:ANP32B(gene name)|psi-mi:ANP32B(display_short)|uniprotkb:APRIL(gene name synonym)|uniprotkb:PHAPI2(gene name synonym)|uniprotkb:Putative HLA-DR-associated protein I-2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_006392.1|ensembl:ENSG00000136938(gene)|ensembl:ENST00000339399(transcript)|go:"GO:0001944"(vasculature development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0021591"(ventricular system development)|go:"GO:0042393"(histone binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048839"(inner ear development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675|mint:Q92688|rcsb pdb:2ELL|rcsb pdb:2RR6|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal) - - comment:"author score: 30" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:8eu0C8oHWUrZ28F2fIup9o5MDYk9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P13667 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-1054653|uniprotkb:A8K4K6|uniprotkb:Q549T6|ensembl:ENSP00000499129 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:pdia4_human(display_long)|uniprotkb:Endoplasmic reticulum resident protein 72(gene name synonym)|uniprotkb:PDIA4(gene name)|psi-mi:PDIA4(display_short)|uniprotkb:ERP70(gene name synonym)|uniprotkb:ERP72(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 70(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_004902.1|ensembl:ENSG00000155660(gene)|ensembl:ENST00000652332(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0009306"(protein secretion)|go:"GO:0009986"(cell surface)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017068(Protein disulphide-isomerase A4)|interpro:IPR017937|interpro:IPR036249|interpro:IPR041866|mint:P13667|rcsb pdb:3IDV - - comment:"author score: 30" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:m9nI8RSOEnIsBjDnQa4fbkT+v2Y9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P61604 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-711483|uniprotkb:O95421|uniprotkb:Q04984|uniprotkb:Q53X54|ensembl:ENSP00000233893|uniprotkb:Q9UDH0 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:ch10_human(display_long)|uniprotkb:HSPE1(gene name)|psi-mi:HSPE1(display_short)|uniprotkb:10 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 10(gene name synonym)|uniprotkb:Early-pregnancy factor(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N interpro:IPR020818|interpro:IPR037124|mint:P61604|rcsb pdb:4PJ1|rcsb pdb:6HT7|rcsb pdb:6MRC|rcsb pdb:6MRD|reactome:R-HSA-9013408|ensembl:ENSG00000115541(gene)|ensembl:ENST00000233893(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR011032(GroES-like)|interpro:IPR018369|refseq:NP_002148.1 - - comment:"author score: 30" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:BmnGoMnA2QIr3Dr0fElMtTgRztA9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P00558 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-709599|uniprotkb:A8K4W6|uniprotkb:Q5J7W1|uniprotkb:Q6IBT6|uniprotkb:Q8NI87|uniprotkb:B7Z7A9|ensembl:ENSP00000362413 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:pgk1_human(display_long)|uniprotkb:Primer recognition protein 2(gene name synonym)|uniprotkb:Cell migration-inducing gene 10 protein(gene name synonym)|uniprotkb:PGK1(gene name)|psi-mi:PGK1(display_short)|uniprotkb:PGKA(gene name synonym)|uniprotkb:OK/SW-cl.110(orf name)|uniprotkb:MIG10(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_000282.1|dip:DIP-33679N|ensembl:ENSG00000102144(gene)|ensembl:ENST00000373316(transcript)|go:"GO:0004618"(phosphoglycerate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0016020"(membrane)|go:"GO:0016310"(phosphorylation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031639"(plasminogen activation)|go:"GO:0043531"(ADP binding)|go:"GO:0045121"(membrane raft)|go:"GO:0047134"("protein-disulfide reductase (NAD(P)) activity")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR001576(Phosphoglycerate kinase)|interpro:IPR015824(Phosphoglycerate kinase, N-terminal)|interpro:IPR015911(Phosphoglycerate kinase, conserved site)|interpro:IPR036043|mint:P00558|rcsb pdb:2WZB|rcsb pdb:2WZC|rcsb pdb:2WZD|rcsb pdb:2X13|rcsb pdb:2X14|rcsb pdb:2X15|rcsb pdb:2XE6|rcsb pdb:2XE7|rcsb pdb:2XE8|rcsb pdb:2Y3I|rcsb pdb:2YBE|rcsb pdb:2ZGV|rcsb pdb:3C39|rcsb pdb:3C3A|rcsb pdb:3C3B|rcsb pdb:3C3C|rcsb pdb:3ZOZ|rcsb pdb:4AXX|rcsb pdb:4O33|rcsb pdb:5M1R|rcsb pdb:5M3U|rcsb pdb:5M6Z|rcsb pdb:5MXM|rcsb pdb:5NP8|rcsb pdb:5O7D|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667 - - comment:"author score: 31" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:fkyBDnIx/ii6vfJjWJsxWi0piOQ9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:Q9UII2 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-718459|uniprotkb:Q5JXL8|uniprotkb:Q6IAQ7|uniprotkb:Q9BSL9|ensembl:ENSP00000335203|ensembl:ENSP00000494248 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:atif1_human(display_long)|uniprotkb:ATP synthase F1 subunit epsilon(gene name synonym)|uniprotkb:ATPI(gene name synonym)|uniprotkb:ATPIF1(gene name synonym)|uniprotkb:"Inhibitor of F(1)F(o)-ATPase"(gene name synonym)|uniprotkb:ATP5IF1(gene name)|psi-mi:ATP5IF1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_057395.1|refseq:NP_835497.1|refseq:NP_835498.1|ensembl:ENSG00000130770(gene)|ensembl:ENSG00000285390(gene)|ensembl:ENST00000335514(transcript)|ensembl:ENST00000647074(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0009986"(cell surface)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042030"(ATPase inhibitor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043532"(angiostatin binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051882"(mitochondrial depolarization)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0140260"(mitochondrial proton-transporting ATP synthase complex binding)|go:"GO:1901030"(positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1903052"(positive regulation of proteolysis involved in cellular protein catabolic process)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:1903578"(regulation of ATP metabolic process)|go:"GO:1904925"(positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization)|interpro:IPR007648(Mitochondrial ATPase inhibitor, IATP)|mint:Q9UII2|go:"GO:0051346"(negative regulation of hydrolase activity) - - comment:"author score: 32" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:KLbFWln/ZxNq87OFWJRU6OzkHtc9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:Q9NQG5 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-747925|uniprotkb:Q1WDE7|uniprotkb:Q6PKF4|ensembl:ENSP00000362532 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:rpr1b_human(display_long)|uniprotkb:RPRD1B(gene name)|psi-mi:RPRD1B(display_short)|uniprotkb:C20orf77(gene name synonym)|uniprotkb:CREPT(gene name synonym)|uniprotkb:Cell cycle-related and expression-elevated protein in tumor(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_067038.1|ensembl:ENSG00000101413(gene)|ensembl:ENST00000373433(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q9NQG5|rcsb pdb:4FLA|rcsb pdb:4FU3|rcsb pdb:4HFG|rcsb pdb:4NAD|rcsb pdb:4Q94|rcsb pdb:4Q96|reactome:R-HSA-6807505|dip:DIP-61537N - - comment:"author score: 33" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:1P0sOiLV5eQXrRj+vENpc6L/z/Q9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P30101 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-979862|uniprotkb:Q13453|uniprotkb:Q14255|uniprotkb:Q8IYF8|uniprotkb:Q9UMU7|ensembl:ENSP00000300289 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:pdia3_human(display_long)|uniprotkb:Disulfide isomerase ER-60(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 60(gene name synonym)|uniprotkb:58 kDa microsomal protein(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 57(gene name synonym)|uniprotkb:58 kDa glucose-regulated protein(gene name synonym)|uniprotkb:PDIA3(gene name)|psi-mi:PDIA3(display_short)|uniprotkb:ERP60(gene name synonym)|uniprotkb:GRP58(gene name synonym)|uniprotkb:ERP57(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N interpro:IPR036249|interpro:IPR041868|mint:P30101|rcsb pdb:2ALB|rcsb pdb:2DMM|rcsb pdb:2H8L|rcsb pdb:3F8U|rcsb pdb:6ENY|reactome:R-HSA-1236974|reactome:R-HSA-901042|reactome:R-HSA-983170|interpro:IPR017937|ensembl:ENSG00000167004(gene)|ensembl:ENST00000300289(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004629"(phospholipase C activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0009986"(cell surface)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|refseq:NP_005304.3|dip:DIP-29132N - - comment:"author score: 33" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:N/XktiLWB/cPju9nCq6yeyXnO1Q9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:B2RPK0 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-13943428 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:hgb1a_human(display_long)|uniprotkb:HMGB1P1(gene name)|psi-mi:HMGB1P1(display_short)|uniprotkb:HMG1L1(gene name synonym)|uniprotkb:HMGB1L1(gene name synonym)|uniprotkb:High mobility group protein B1 pseudogene 1(gene name synonym)|uniprotkb:Putative high mobility group protein 1-like 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008301"(DNA binding, bending)|mint:B2RPK0|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR031076|interpro:IPR036910 - - comment:"author score: 34" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:ppgkTWseGeSKMW8zLWwg1AmkhlY9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P80723 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-358583|uniprotkb:D3DTD5|uniprotkb:O43596|uniprotkb:Q5U0S0|uniprotkb:Q9BWA5|uniprotkb:B4DJA8|ensembl:ENSP00000319281|ensembl:ENSP00000482066 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:basp1_human(display_long)|uniprotkb:BASP1(gene name)|psi-mi:BASP1(display_short)|uniprotkb:NAP22(gene name synonym)|uniprotkb:Neuronal axonal membrane protein NAP-22(gene name synonym)|uniprotkb:22 kDa neuronal tissue-enriched acidic protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_006308.3|refseq:NP_001258535.1|ensembl:ENSG00000176788(gene)|ensembl:ENST00000322611(transcript)|ensembl:ENST00000616743(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0008406"(gonad development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030054"(cell junction)|go:"GO:0030426"(growth cone)|go:"GO:0031982"(vesicle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0060231"(mesenchymal to epithelial transition)|go:"GO:0060421"(positive regulation of heart growth)|go:"GO:0060539"(diaphragm development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072075"(metanephric mesenchyme development)|go:"GO:0072112"(glomerular visceral epithelial cell differentiation)|go:"GO:2001076"(positive regulation of metanephric ureteric bud development)|interpro:IPR008408(Brain acid soluble protein 1)|mint:P80723|reactome:R-HSA-9035034 - - comment:"author score: 36" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:X+L20HKimV3J+vLnQljg+x78+e09606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P16949 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-445909|uniprotkb:A2A2D1|uniprotkb:B7Z8N4|uniprotkb:D3DPJ5|uniprotkb:B2R4E7|ensembl:ENSP00000350531|ensembl:ENSP00000363409|ensembl:ENSP00000382633|ensembl:ENSP00000387858 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:stmn1_human(display_long)|uniprotkb:Phosphoprotein p19(gene name synonym)|uniprotkb:Leukemia-associated phosphoprotein p18(gene name synonym)|uniprotkb:Oncoprotein 18(gene name synonym)|uniprotkb:pp17(gene name synonym)|uniprotkb:Prosolin(gene name synonym)|uniprotkb:Metablastin(gene name synonym)|uniprotkb:Protein Pr22(gene name synonym)|uniprotkb:STMN1(gene name)|psi-mi:STMN1(display_short)|uniprotkb:LAP18(gene name synonym)|uniprotkb:OP18(gene name synonym)|uniprotkb:C1orf215(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_001138926.1|refseq:NP_005554.1|refseq:NP_981944.1|refseq:NP_981946.1|ensembl:ENST00000357865(transcript)|ensembl:ENST00000374291(transcript)|ensembl:ENST00000399728(transcript)|ensembl:ENST00000455785(transcript)|go:"GO:0000281"(mitotic cytokinesis)|ensembl:ENSG00000117632(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0009615"(response to virus)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0031115"(negative regulation of microtubule polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043005"(neuron projection)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|mint:P16949|interpro:IPR000956(Stathmin)|interpro:IPR030514|interpro:IPR036002|reactome:R-HSA-1251985 - - comment:"author score: 37" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:gew+NqUuLLolCLCXOyXIZkRieIs9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P08758 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-296601|ensembl:ENSP00000296511|uniprotkb:Q6FI16|uniprotkb:Q8WV69|uniprotkb:Q6FHB3|uniprotkb:Q9UDH9|uniprotkb:D3DNW7 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:anxa5_human(display_long)|uniprotkb:ANXA5(gene name)|psi-mi:ANXA5(display_short)|uniprotkb:ANX5(gene name synonym)|uniprotkb:ENX2(gene name synonym)|uniprotkb:PP4(gene name synonym)|uniprotkb:Annexin-5(gene name synonym)|uniprotkb:Annexin V(gene name synonym)|uniprotkb:Lipocortin V(gene name synonym)|uniprotkb:Endonexin II(gene name synonym)|uniprotkb:Calphobindin I(gene name synonym)|uniprotkb:Placental anticoagulant protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein 4(gene name synonym)|uniprotkb:Thromboplastin inhibitor(gene name synonym)|uniprotkb:Vascular anticoagulant-alpha(gene name synonym)|uniprotkb:Anchorin CII(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N ensembl:ENSG00000164111(gene)|ensembl:ENST00000296511(transcript)|go:"GO:0004859"(phospholipase inhibitor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007596"(blood coagulation)|go:"GO:0016020"(membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050819"(negative regulation of coagulation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001464(Annexin)|interpro:IPR002392(Annexin, type V)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P08758|rcsb pdb:1ANW|rcsb pdb:1ANX|rcsb pdb:1AVH|rcsb pdb:1AVR|rcsb pdb:1HAK|rcsb pdb:1HVD|rcsb pdb:1HVE|rcsb pdb:1HVF|rcsb pdb:1HVG|rcsb pdb:1SAV|rcsb pdb:2XO2|rcsb pdb:2XO3|rcsb pdb:6K22|rcsb pdb:6K25|reactome:R-HSA-114608|refseq:NP_001145.1 - - comment:"author score: 40" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:vIp2wWkAz7uOtQSzbUJick5bT5o9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P20962 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-724050|ensembl:ENSP00000310088 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:ptms_human(display_long)|uniprotkb:PTMS(gene name)|psi-mi:PTMS(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_002815.3|ensembl:ENSG00000159335(gene)|ensembl:ENST00000309083(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|interpro:IPR004931(Prothymosin/parathymosin)|mint:P20962 - - comment:"author score: 41" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:iELnzobQCJMa28yQCYCaO4h6/nE9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P05114 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-3915525|uniprotkb:Q3KQR8|ensembl:ENSP00000370125 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:hmgn1_human(display_long)|uniprotkb:HMGN1(gene name)|psi-mi:HMGN1(display_short)|uniprotkb:HMG14(gene name synonym)|uniprotkb:High mobility group nucleosome-binding domain-containing protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_004956.5|ensembl:ENSG00000205581(gene)|ensembl:ENST00000380749(transcript)|go:"GO:0000720"(pyrimidine dimer repair by nucleotide-excision repair)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010224"(response to UV-B)|go:"GO:0010225"(response to UV-C)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0048597"(post-embryonic camera-type eye morphogenesis)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:1901666"(positive regulation of NAD+ ADP-ribosyltransferase activity)|interpro:IPR000079(High mobility group protein HMG14 and HMG17)|mint:P05114|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210 - - comment:"author score: 41" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:2Ns7EUwCgpj8Gj6uTuB1K6UZksc9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P00441 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-990792|uniprotkb:A6NHJ0|uniprotkb:Q16669|uniprotkb:Q16711|uniprotkb:Q16838|uniprotkb:Q16839|uniprotkb:Q16840|uniprotkb:Q6NR85|ensembl:ENSP00000270142|uniprotkb:D3DSE4 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:sodc_human(display_long)|uniprotkb:Superoxide dismutase 1(gene name synonym)|uniprotkb:SOD1(gene name)|psi-mi:SOD1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N ensembl:ENSG00000142168(gene)|ensembl:ENST00000270142(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000303"(response to superoxide)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001890"(placenta development)|go:"GO:0001895"(retina homeostasis)|go:"GO:0002262"(myeloid cell homeostasis)|go:"GO:0004784"(superoxide dismutase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005764"(lysosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007566"(embryo implantation)|go:"GO:0007569"(cell aging)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0001975"(response to amphetamine)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033081"(regulation of T cell differentiation in thymus)|go:"GO:0034465"(response to carbon monoxide)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009408"(response to heat)|go:"GO:0010033"(response to organic substance)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0031045"(dense core granule)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031667"(response to nutrient levels)|interpro:IPR024134|interpro:IPR036423|mint:P00441|rcsb pdb:1AZV|rcsb pdb:1BA9|rcsb pdb:1DSW|rcsb pdb:1FUN|rcsb pdb:1HL4|rcsb pdb:1HL5|rcsb pdb:1KMG|rcsb pdb:1L3N|rcsb pdb:1MFM|rcsb pdb:1N18|rcsb pdb:1N19|interpro:IPR018152|rcsb pdb:1OEZ|rcsb pdb:1OZT|rcsb pdb:1OZU|rcsb pdb:1P1V|rcsb pdb:1PTZ|rcsb pdb:1PU0|rcsb pdb:1RK7|rcsb pdb:1SOS|rcsb pdb:1SPD|rcsb pdb:1UXL|rcsb pdb:1UXM|rcsb pdb:2AF2|rcsb pdb:2C9S|rcsb pdb:2C9U|rcsb pdb:2C9V|rcsb pdb:2GBT|rcsb pdb:2GBU|rcsb pdb:2GBV|rcsb pdb:2LU5|rcsb pdb:2MP3|rcsb pdb:2NAM|rcsb pdb:2NNX|rcsb pdb:2R27|rcsb pdb:2V0A|rcsb pdb:2VR6|rcsb pdb:2VR7|rcsb pdb:2VR8|rcsb pdb:2WKO|rcsb pdb:2WYT|rcsb pdb:2WYZ|rcsb pdb:2WZ0|rcsb pdb:2WZ5|rcsb pdb:2WZ6|rcsb pdb:2XJK|rcsb pdb:2XJL|rcsb pdb:2ZKW|rcsb pdb:2ZKX|rcsb pdb:2ZKY|rcsb pdb:3CQP|rcsb pdb:3CQQ|rcsb pdb:3ECU|rcsb pdb:3ECV|rcsb pdb:3ECW|rcsb pdb:3GQF|rcsb pdb:3GTV|rcsb pdb:3GZO|rcsb pdb:3GZP|rcsb pdb:3GZQ|rcsb pdb:3H2P|rcsb pdb:3H2Q|rcsb pdb:3HFF|rcsb pdb:3K91|rcsb pdb:3KH3|rcsb pdb:3KH4|rcsb pdb:3LTV|rcsb pdb:3QQD|rcsb pdb:3RE0|rcsb pdb:3T5W|rcsb pdb:4A7G|rcsb pdb:4A7Q|rcsb pdb:4A7S|rcsb pdb:4A7T|rcsb pdb:4A7U|rcsb pdb:4A7V|rcsb pdb:4B3E|rcsb pdb:4BCY|rcsb pdb:4BCZ|rcsb pdb:4BD4|rcsb pdb:4FF9|rcsb pdb:4MCM|rcsb pdb:4MCN|rcsb pdb:4NIN|rcsb pdb:4NIO|rcsb pdb:4NIP|rcsb pdb:4OH2|rcsb pdb:4SOD|rcsb pdb:4XCR|rcsb pdb:5DLI|rcsb pdb:5IIW|rcsb pdb:5J07|rcsb pdb:5J0C|rcsb pdb:5J0F|rcsb pdb:5J0G|rcsb pdb:5K02|rcsb pdb:5O3Y|rcsb pdb:5O40|rcsb pdb:5U9M|rcsb pdb:5WOR|rcsb pdb:5YTO|rcsb pdb:5YTU|rcsb pdb:5YUL|rcsb pdb:6A9O|rcsb pdb:6B79|rcsb pdb:6DTK|rcsb pdb:6FFK|rcsb pdb:6FLH|rcsb pdb:6FOI|rcsb pdb:6FOL|rcsb pdb:6FON|rcsb pdb:6FP6|rcsb pdb:6SPA|rcsb pdb:6SPH|rcsb pdb:6SPI|rcsb pdb:6SPJ|rcsb pdb:6SPK|rcsb pdb:6Z3V|rcsb pdb:6Z4G|rcsb pdb:6Z4H|rcsb pdb:6Z4I|rcsb pdb:6Z4J|rcsb pdb:6Z4K|rcsb pdb:6Z4L|rcsb pdb:6Z4M|rcsb pdb:6Z4O|reactome:R-HSA-114608|reactome:R-HSA-3299685|reactome:R-HSA-8950505|rcsb pdb:5WMJ|go:"GO:0046688"(response to copper ion)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048538"(thymus development)|go:"GO:0048678"(response to axon injury)|go:"GO:0050665"(hydrogen peroxide biosynthetic process)|go:"GO:0046677"(response to antibiotic)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051087"(chaperone binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060047"(heart contraction)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0060087"(relaxation of vascular associated smooth muscle)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097332"(response to antipsychotic drug)|go:"GO:1902177"(positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001424(Superoxide dismutase, copper/zinc binding)|refseq:NP_000445.1|dip:DIP-44941N - - comment:"author score: 42" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:W5O3CdnrxKm1kudXW04wxnCxTY09606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P27797 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-1049597|uniprotkb:Q6IAT4|uniprotkb:Q9UDG2|ensembl:ENSP00000320866|ensembl:ENSP00000466037 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:calr_human(display_long)|uniprotkb:CRP55(gene name synonym)|uniprotkb:Calregulin(gene name synonym)|uniprotkb:HACBP(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 60(gene name synonym)|uniprotkb:grp60(gene name synonym)|uniprotkb:CALR(gene name)|psi-mi:CALR(display_short)|uniprotkb:CRTC(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_004334.1|ensembl:ENSG00000179218(gene)|ensembl:ENST00000316448(transcript)|ensembl:ENST00000586967(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0002502"(peptide antigen assembly with MHC class I protein complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005506"(iron ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0033574"(response to testosterone)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0042277"(peptide binding)|go:"GO:0042493"|go:"GO:0042562"(hormone binding)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051208"(sequestering of calcium ion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060473"(cortical granule)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0090398"(cellular senescence)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901164"(negative regulation of trophoblast cell migration)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR009169(Calreticulin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27797|rcsb pdb:2CLR|rcsb pdb:3DOW|rcsb pdb:3POS|rcsb pdb:3POW|rcsb pdb:5LK5|rcsb pdb:5V90|rcsb pdb:6ENY|reactome:R-HSA-1236974|reactome:R-HSA-168316|reactome:R-HSA-3000480|reactome:R-HSA-3000484|reactome:R-HSA-381183|reactome:R-HSA-901042|reactome:R-HSA-983170|dip:DIP-104N - - comment:"author score: 44" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:FSPSiiN6YTaETDyAWwAP3wV6zRI9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P23284 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-359252|uniprotkb:Q9BVK5|uniprotkb:A8K534|uniprotkb:Q6IBH5|ensembl:ENSP00000300026 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:ppib_human(display_long)|uniprotkb:PPIB(gene name)|psi-mi:PPIB(display_short)|uniprotkb:CYPB(gene name synonym)|uniprotkb:Cyclophilin B(gene name synonym)|uniprotkb:S-cyclophilin(gene name synonym)|uniprotkb:CYP-S1(gene name synonym)|uniprotkb:Rotamase B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N refseq:NP_000933.1|ensembl:ENSG00000166794(gene)|ensembl:ENST00000300026(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003723"(RNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016020"(membrane)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042470"(melanosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0060348"(bone development)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000|mint:P23284|rcsb pdb:1CYN|rcsb pdb:3ICH|rcsb pdb:3ICI|reactome:R-HSA-1650814 - - comment:"author score: 45" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:h6nKaPUyEYUctYuu/3XfFhM4y9c9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P07737 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-713780|ensembl:ENSP00000225655|uniprotkb:Q53Y44 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:prof1_human(display_long)|uniprotkb:Profilin I(gene name synonym)|uniprotkb:PFN1(gene name)|psi-mi:PFN1(display_short)|uniprotkb:Epididymis tissue protein Li 184a(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N ensembl:ENSG00000108518(gene)|ensembl:ENST00000225655(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0060074"(synapse maturation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0072562"(blood microparticle)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900029"(positive regulation of ruffle assembly)|interpro:IPR005454(Profilin, Mammalian)|interpro:IPR005455(Profilin, plant)|interpro:IPR027310|interpro:IPR029892|interpro:IPR036140|mint:P07737|rcsb pdb:1AWI|rcsb pdb:1CF0|rcsb pdb:1CJF|rcsb pdb:1FIK|rcsb pdb:1FIL|rcsb pdb:1PFL|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:3CHW|rcsb pdb:4X1L|rcsb pdb:4X1M|rcsb pdb:4X25|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6NBW|reactome:R-HSA-114608|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|reactome:R-HSA-4086400|reactome:R-HSA-5663220|reactome:R-HSA-376176|refseq:NP_005013.1|dip:DIP-30N - - comment:"author score: 48" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:CncaC5RMylvzFLhqzpS+VbhQn6I9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P61956 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-473220|uniprotkb:P55855|uniprotkb:Q6IPZ6|ensembl:ENSP00000405965|uniprotkb:Q32Q42|uniprotkb:Q96HK1|intact:EBI-2512339|uniprotkb:B2R4I2 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:sumo2_human(display_long)|uniprotkb:SMT3 homolog 2(gene name synonym)|uniprotkb:Sentrin-2(gene name synonym)|uniprotkb:HSMT3(gene name synonym)|uniprotkb:SUMO-3(gene name synonym)|uniprotkb:SUMO2(gene name)|psi-mi:SUMO2(display_short)|uniprotkb:SMT3H2(gene name synonym)|uniprotkb:SMT3B(gene name synonym)|uniprotkb:Ubiquitin-like protein SMT3B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N rcsb pdb:1Z5Q|rcsb pdb:2AWT|rcsb pdb:2CKH|rcsb pdb:2D07|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|mint:P61956|rcsb pdb:1WM2|rcsb pdb:1WM3|rcsb pdb:1WZ0|rcsb pdb:2IO0|ensembl:ENSG00000188612(gene)|ensembl:ENST00000420826(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|refseq:NP_001005849.1|refseq:NP_008868.3|rcsb pdb:2IO3|rcsb pdb:6JXW|rcsb pdb:6JXX|reactome:R-HSA-196791|reactome:R-HSA-3065676|reactome:R-HSA-3065678|reactome:R-HSA-3065679|reactome:R-HSA-3108214|reactome:R-HSA-3232118|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5693607|reactome:R-HSA-5696395|rcsb pdb:5GHC|rcsb pdb:5D2M|rcsb pdb:5ELU|rcsb pdb:5EQL|rcsb pdb:5GHB|rcsb pdb:2IYD|rcsb pdb:2N1W|rcsb pdb:2N9E|rcsb pdb:2RPQ|rcsb pdb:3UIN|rcsb pdb:3UIO|rcsb pdb:3ZO5|rcsb pdb:4BKG|rcsb pdb:4NPN|dip:DIP-29253N - - comment:"author score: 49" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:WgudlZhwtQbQInv29BniecTYGY89606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P46934 uniprotkb:P62158 intact:EBI-726944|ensembl:ENSP00000424827|uniprotkb:A1KY35|uniprotkb:A6ND72|uniprotkb:A7MD29|uniprotkb:B4E2R7|uniprotkb:B7ZM59|uniprotkb:B7ZM60|uniprotkb:B9EGN5|uniprotkb:D6RF89|intact:EBI-28969445 intact:EBI-397435|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q13942|uniprotkb:Q53S29|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q96HK3|uniprotkb:P0DP25|uniprotkb:P0DP24|uniprotkb:P0DP23 psi-mi:nedd4_human(display_long)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 4(gene name synonym)|uniprotkb:NEDD4(gene name)|psi-mi:NEDD4(display_short)|uniprotkb:KIAA0093(gene name synonym)|uniprotkb:NEDD4-1(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 53 protein(gene name synonym)|uniprotkb:PIG53(orf name)|uniprotkb:HECT-type E3 ubiquitin transferase NEDD4(gene name synonym) psi-mi:calm_human(display_long)|uniprotkb:CALM1(gene name)|psi-mi:CALM1(display_short)|uniprotkb:CALM(gene name synonym)|uniprotkb:CAM(gene name synonym)|uniprotkb:CAM1(gene name synonym)|uniprotkb:CALM2(gene name)|psi-mi:CALM2(display_short)|uniprotkb:CAMB(gene name synonym)|uniprotkb:CALM3(gene name)|psi-mi:CALM3(display_short)|uniprotkb:CAM3(gene name synonym)|uniprotkb:CAMC(gene name synonym)|uniprotkb:CAMIII(gene name synonym)|uniprotkb:CAM2(gene name synonym)|uniprotkb:CALML2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481662|imex:IM-26985-257 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271267.1|refseq:NP_001271268.1|refseq:NP_001271269.1|ensembl:ENSG00000069869(gene)|ensembl:ENST00000508342(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0010766"(negative regulation of sodium ion transport)|go:"GO:0010768"(negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031175"(neuron projection development)|go:"GO:0031623"(receptor internalization)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043197"(dendritic spine)|go:"GO:0044111"(formation of structure involved in a symbiotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046755"(viral budding)|go:"GO:0046824"(positive regulation of nucleocytoplasmic transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0050816"(phosphothreonine residue binding)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051592"(response to calcium ion)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|mint:P46934|rcsb pdb:2KPZ|rcsb pdb:2KQ0|go:"GO:0050815"(phosphoserine residue binding)|rcsb pdb:2M3O|rcsb pdb:2XBB|rcsb pdb:2XBF|rcsb pdb:3B7Y|rcsb pdb:4BBN|rcsb pdb:4BE8|rcsb pdb:4N7F|rcsb pdb:4N7H|rcsb pdb:5AHT|rcsb pdb:5C7J|rcsb pdb:5C91|reactome:R-HSA-1169408|reactome:R-HSA-1253288|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-983168|refseq:NP_006145.2|refseq:NP_940682.2|ensembl:ENST00000338963|ensembl:ENSP00000345530|ensembl:ENST00000435532|ensembl:ENSP00000410613|ensembl:ENST00000506154|ensembl:ENSP00000422705|ensembl:ENSP00000424827|refseq:NP_001316141.1|dip:DIP-29815N rcsb pdb:3SUI|rcsb pdb:2LGF|rcsb pdb:2LQC|rcsb pdb:2LQP|rcsb pdb:2Y4V|rcsb pdb:4JQ0|rcsb pdb:4LZX|rcsb pdb:4M1L|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:3J41|rcsb pdb:2LL6|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0030017"(sarcomere)|go:"GO:0030801"(obsolete positive regulation of cyclic nucleotide metabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|rcsb pdb:2LV6|rcsb pdb:2N6A|refseq:NP_001734.1|refseq:NP_005175.2|refseq:NP_008819.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0000922"(spindle pole)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006936"(muscle contraction)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0002576"(platelet degranulation)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0050999"(regulation of nitric-oxide synthase activity)|rcsb pdb:1AJI|rcsb pdb:1CDL|rcsb pdb:1CLL|rcsb pdb:1CTR|rcsb pdb:1IWQ|rcsb pdb:1J7O|rcsb pdb:1J7P|rcsb pdb:1K90|rcsb pdb:1K93|rcsb pdb:1L7Z|rcsb pdb:1LVC|rcsb pdb:1NKF|rcsb pdb:1PK0|rcsb pdb:1S26|rcsb pdb:1SK6|rcsb pdb:1SW8|rcsb pdb:1WRZ|rcsb pdb:1XFU|rcsb pdb:1XFV|rcsb pdb:1XFW|rcsb pdb:1XFX|rcsb pdb:1XFY|rcsb pdb:1XFZ|rcsb pdb:1Y6W|rcsb pdb:1YR5|rcsb pdb:1YRT|rcsb pdb:1YRU|rcsb pdb:1ZOT|rcsb pdb:1ZUZ|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2HF5|rcsb pdb:2I08|rcsb pdb:2JZI|rcsb pdb:2K0E|rcsb pdb:2K0F|rcsb pdb:2K0J|rcsb pdb:2K61|rcsb pdb:2KNE|rcsb pdb:2KUG|rcsb pdb:2KUH|rcsb pdb:2L53|rcsb pdb:2L7L|rcsb pdb:2R28|rcsb pdb:2V01|rcsb pdb:2V02|rcsb pdb:2VAY|rcsb pdb:2W73|rcsb pdb:2WEL|rcsb pdb:2X0G|rcsb pdb:3BYA|rcsb pdb:3DVE|rcsb pdb:3DVJ|rcsb pdb:3DVK|rcsb pdb:3DVM|rcsb pdb:3EWT|rcsb pdb:3EWV|rcsb pdb:3G43|rcsb pdb:3HR4|rcsb pdb:3O77|rcsb pdb:3O78|rcsb pdb:3OXQ|rcsb pdb:3UCT|rcsb pdb:3UCW|rcsb pdb:3UCY|rcsb pdb:4DCK|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0000165"(MAPK cascade)|rcsb pdb:2M0J|rcsb pdb:2M0K|rcsb pdb:4UMO|rcsb pdb:4V0C|go:"GO:0031982"(vesicle)|rcsb pdb:4Q5U|rcsb pdb:4UPU|reactome:R-HSA-2672351|reactome:R-HSA-418359|reactome:R-HSA-425561|reactome:R-HSA-5576892|reactome:R-HSA-5578775|reactome:R-HSA-936837|refseq:NP_001292555.1|rcsb pdb:4OVN|rcsb pdb:5COC|go:"GO:0021762"(substantia nigra development)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:4BW7|rcsb pdb:4BW8|rcsb pdb:4L79|rcsb pdb:5DBR|rcsb pdb:4DJC|rcsb pdb:2M55|rcsb pdb:2LL7|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030426"(growth cone)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051412"(response to corticosterone)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|rcsb pdb:2N77|go:"GO:0032991"(protein-containing complex)|go:"GO:0006479"(protein methylation)|go:"GO:0014069"(postsynaptic density)|rcsb pdb:5DSU|reactome:R-HSA-8876725|rcsb pdb:4GOW|rcsb pdb:4Q57|go:"GO:0043647"(inositol phosphate metabolic process)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031432"(titin binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0031997"(N-terminal myristoylation domain binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055117"(regulation of cardiac muscle contraction)|rcsb pdb:2MG5|go:"GO:0005088"|go:"GO:0007223"(Wnt signaling pathway, calcium modulating pathway)|go:"GO:0008440"(inositol-1,4,5-trisphosphate 3-kinase activity)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0005634"(nucleus)|rcsb pdb:4JPZ|ensembl:ENST00000272298|ensembl:ENST00000291295|ensembl:ENST00000356978|ensembl:ENST00000596362|refseq:NP_001292553.1|refseq:NP_001292554.1|rcsb pdb:4BYF|reactome:R-HSA-111932|reactome:R-HSA-111933|reactome:R-HSA-111957|reactome:R-HSA-111997|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-1474151|reactome:R-HSA-180024|reactome:R-HSA-1855204|reactome:R-HSA-203615|reactome:R-HSA-2514859|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-442717|reactome:R-HSA-442729|reactome:R-HSA-442745|reactome:R-HSA-442982|reactome:R-HSA-445355|reactome:R-HSA-451308|reactome:R-HSA-5218920|reactome:R-HSA-5218921|reactome:R-HSA-5607763|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5673001|reactome:R-HSA-70221|reactome:R-HSA-983695|ensembl:ENSG00000143933|ensembl:ENSG00000160014|ensembl:ENSG00000198668|ensembl:ENSP00000272298|ensembl:ENSP00000291295|ensembl:ENSP00000349467|ensembl:ENSP00000472141|rcsb pdb:5NIN|rcsb pdb:5VMS|rcsb pdb:5WSU|rcsb pdb:5WSV|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|rcsb pdb:2N8J|rcsb pdb:5GGM|rcsb pdb:5J8H|reactome:R-HSA-163615|reactome:R-HSA-5210891|refseq:NP_001316851.1|refseq:NP_001316852.1|refseq:NP_001316853.1|refseq:NP_001316854.1|refseq:NP_001316855.1|rcsb pdb:2N27|rcsb pdb:5DOW|rcsb pdb:5I0I|rcsb pdb:5J03|rcsb pdb:5K7L|rcsb pdb:5K8Q|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0043388"(positive regulation of DNA binding)|dip:DIP-31794N|rcsb pdb:1UP5|rcsb pdb:5JQA|rcsb pdb:5JTH|rcsb pdb:5OEO|rcsb pdb:5TP5|rcsb pdb:5TP6|rcsb pdb:5V02|rcsb pdb:5V03|rcsb pdb:5V7X|rcsb pdb:5WBX|rcsb pdb:5WC5|rcsb pdb:6B8L|rcsb pdb:6B8M|rcsb pdb:6B8N|rcsb pdb:6B8P|rcsb pdb:6B8Q|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6CNM|rcsb pdb:6CNN|rcsb pdb:6CNO|rcsb pdb:6FEG|rcsb pdb:6FEH|reactome:R-HSA-2025928|reactome:R-HSA-2151201|go:"GO:0034704"(calcium channel complex)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0051186"(obsolete cofactor metabolic process)|go:"GO:0075206"(obsolete positive regulation by host of symbiont cAMP-mediated signal transduction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|interpro:IPR039030|go:"GO:1902494"(catalytic complex)|go:"GO:0043234"|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0030819"(obsolete positive regulation of cAMP biosynthetic process)|rcsb pdb:6BUT|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6DAF|rcsb pdb:6DAH|rcsb pdb:6E2F|rcsb pdb:6E2G|rcsb pdb:6EEB|rcsb pdb:6GDK|rcsb pdb:6GDL|rcsb pdb:6HCS|rcsb pdb:6JI8|rcsb pdb:6JII|rcsb pdb:6JIU|rcsb pdb:6JIY|rcsb pdb:6JRS|rcsb pdb:6JV2|rcsb pdb:6K4K|rcsb pdb:6K4L|rcsb pdb:6K4R|rcsb pdb:6MUD|rcsb pdb:6MUE|rcsb pdb:6N5W|rcsb pdb:6O5G|reactome:R-HSA-438066|reactome:R-HSA-442720|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802949|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9009391|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9617324|reactome:R-HSA-9619229|reactome:R-HSA-9619483|reactome:R-HSA-9620244|go:"GO:0019722"(calcium-mediated signaling)|rcsb pdb:6PBX|rcsb pdb:6PBY|reactome:R-HSA-9649948|go:"GO:0005623"(obsolete cell)|rcsb pdb:6HR1|rcsb pdb:6OS4|rcsb pdb:6Y4P|rcsb pdb:6Y94|rcsb pdb:6Y95|reactome:R-HSA-9664323|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0016032"(viral process)|rcsb pdb:6M7H|rcsb pdb:6UZZ|rcsb pdb:6V00|rcsb pdb:6V01|rcsb pdb:6PLM|rcsb pdb:6S5T|rcsb pdb:6SZ5|rcsb pdb:6XXF|rcsb pdb:6Y4O - - comment:"author score: 54" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:R0IvurHHFLE8EYZK1hRLsSwbs5I9606 rogid:tTYcOd9bOh211njZVz7cYVybAMQ9606 rigid:pMwFAv2dz826iMTBYZaq3Cb0K9U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96PU5 uniprotkb:Q4VCS5 intact:EBI-717962|uniprotkb:O43165|uniprotkb:Q7Z5F1|uniprotkb:Q7Z5F2|uniprotkb:Q7Z5N3|uniprotkb:Q8N5A7|uniprotkb:Q8WUU9|uniprotkb:Q9BW58|uniprotkb:Q9H2W4|uniprotkb:Q9NT88|uniprotkb:Q3LSM7|intact:EBI-28979180|ensembl:ENSP00000383199 intact:EBI-2511319|ensembl:ENSP00000361027|uniprotkb:Q504X5|uniprotkb:Q9UPT1|uniprotkb:Q9HD27 psi-mi:ned4l_human(display_long)|uniprotkb:Nedd4-2(gene name synonym)|uniprotkb:NEDD4.2(gene name synonym)|uniprotkb:NEDD4L(gene name)|psi-mi:NEDD4L(display_short)|uniprotkb:KIAA0439(gene name synonym)|uniprotkb:NEDL3(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase NED4L(gene name synonym) psi-mi:amot_human(display_long)|uniprotkb:AMOT(gene name)|psi-mi:AMOT(display_short)|uniprotkb:KIAA1071(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481854|imex:IM-26985-259 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138436.1|refseq:NP_001138437.1|refseq:NP_001138438.1|refseq:NP_001138439.1|refseq:NP_001138440.1|refseq:NP_001138441.1|refseq:NP_001138442.1|refseq:NP_056092.2|refseq:NP_001230889.1|ensembl:ENSP00000383199|ensembl:ENSP00000372301|ensembl:ENST00000431212|ensembl:ENSP00000389406|ensembl:ENST00000435432|ensembl:ENSP00000393395|ensembl:ENST00000456173|ensembl:ENSP00000405440|ensembl:ENST00000456986|ensembl:ENSP00000411947|ensembl:ENST00000586263|ensembl:ENSP00000468546|ensembl:ENST00000674517|ensembl:ENSP00000501665|ensembl:ENST00000675502|ensembl:ENSP00000502428|ensembl:ENST00000675801|ensembl:ENSP00000502688|ensembl:ENST00000675865|ensembl:ENSP00000502003|ensembl:ENST00000676226|ensembl:ENSP00000502325|ensembl:ENST00000256830|ensembl:ENSP00000256830|ensembl:ENST00000356462|ensembl:ENSP00000348847|ensembl:ENST00000357895|ensembl:ENSP00000350569|ensembl:ENST00000382850|refseq:XP_016881168.1|refseq:NP_001138443.1|ensembl:ENSG00000049759(gene)|ensembl:ENST00000400345(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007588"(excretion)|go:"GO:0010038"(response to metal ion)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0030104"(water homeostasis)|go:"GO:0030154"(cell differentiation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR024928|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|rcsb pdb:2LAJ|rcsb pdb:2LB2|rcsb pdb:2LTY|rcsb pdb:2MPT|rcsb pdb:2NSQ|rcsb pdb:2ONI|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:5HPK|reactome:R-HSA-162588|reactome:R-HSA-2173788|reactome:R-HSA-2173795|reactome:R-HSA-2672351|reactome:R-HSA-983168|mint:Q96PU5|dip:DIP-41935N ensembl:ENSG00000126016(gene)|ensembl:ENST00000371959(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006935"(chemotaxis)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035329"(hippo signaling)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q4VCS5|rcsb pdb:6JJX|reactome:R-HSA-2028269|refseq:XP_011529177.1|refseq:NP_001106962.1|refseq:NP_573572.1|refseq:XP_005262144.1|refseq:XP_005262147.1|refseq:XP_016884778.1|dip:DIP-53711N - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:HrKtKY/e1+GYwm5PbBxMO+7XOc09606 rogid:5O9K+GgX1s0Hn5optTeKPOs+X1s9606 rigid:/O+M6dQQVn+IyVuIxCueM/vqBgQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96PU5 uniprotkb:P81605 intact:EBI-717962|uniprotkb:O43165|uniprotkb:Q7Z5F1|uniprotkb:Q7Z5F2|uniprotkb:Q7Z5N3|uniprotkb:Q8N5A7|uniprotkb:Q8WUU9|uniprotkb:Q9BW58|uniprotkb:Q9H2W4|uniprotkb:Q9NT88|uniprotkb:Q3LSM7|intact:EBI-28979180|ensembl:ENSP00000383199 intact:EBI-395625|uniprotkb:P58461|uniprotkb:A5JHP2|uniprotkb:A5JHP3|uniprotkb:Q53YJ2|ensembl:ENSP00000293371 psi-mi:ned4l_human(display_long)|uniprotkb:Nedd4-2(gene name synonym)|uniprotkb:NEDD4.2(gene name synonym)|uniprotkb:NEDD4L(gene name)|psi-mi:NEDD4L(display_short)|uniprotkb:KIAA0439(gene name synonym)|uniprotkb:NEDL3(gene name synonym)|uniprotkb:HECT-type E3 ubiquitin transferase NED4L(gene name synonym) psi-mi:dcd_human(display_long)|uniprotkb:AIDD(gene name synonym)|uniprotkb:DSEP(gene name synonym)|uniprotkb:Preproteolysin(gene name synonym)|uniprotkb:DCD(gene name)|psi-mi:DCD(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481854|imex:IM-26985-259 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001138436.1|refseq:NP_001138437.1|refseq:NP_001138438.1|refseq:NP_001138439.1|refseq:NP_001138440.1|refseq:NP_001138441.1|refseq:NP_001138442.1|refseq:NP_056092.2|refseq:NP_001230889.1|ensembl:ENSP00000383199|ensembl:ENSP00000372301|ensembl:ENST00000431212|ensembl:ENSP00000389406|ensembl:ENST00000435432|ensembl:ENSP00000393395|ensembl:ENST00000456173|ensembl:ENSP00000405440|ensembl:ENST00000456986|ensembl:ENSP00000411947|ensembl:ENST00000586263|ensembl:ENSP00000468546|ensembl:ENST00000674517|ensembl:ENSP00000501665|ensembl:ENST00000675502|ensembl:ENSP00000502428|ensembl:ENST00000675801|ensembl:ENSP00000502688|ensembl:ENST00000675865|ensembl:ENSP00000502003|ensembl:ENST00000676226|ensembl:ENSP00000502325|ensembl:ENST00000256830|ensembl:ENSP00000256830|ensembl:ENST00000356462|ensembl:ENSP00000348847|ensembl:ENST00000357895|ensembl:ENSP00000350569|ensembl:ENST00000382850|refseq:XP_016881168.1|refseq:NP_001138443.1|ensembl:ENSG00000049759(gene)|ensembl:ENST00000400345(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0003254"(regulation of membrane depolarization)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006814"(sodium ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0007588"(excretion)|go:"GO:0010038"(response to metal ion)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019870"(potassium channel inhibitor activity)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0030104"(water homeostasis)|go:"GO:0030154"(cell differentiation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0042176"(regulation of protein catabolic process)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048814"(regulation of dendrite morphogenesis)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901017"(negative regulation of potassium ion transmembrane transporter activity)|go:"GO:1901380"(negative regulation of potassium ion transmembrane transport)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:1903861"(positive regulation of dendrite extension)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000650"(negative regulation of sodium ion transmembrane transporter activity)|go:"GO:2001288"(positive regulation of caveolin-mediated endocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000569(HECT)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR024928|interpro:IPR035892|interpro:IPR035983|interpro:IPR036020|rcsb pdb:2LAJ|rcsb pdb:2LB2|rcsb pdb:2LTY|rcsb pdb:2MPT|rcsb pdb:2NSQ|rcsb pdb:2ONI|rcsb pdb:3JVZ|rcsb pdb:3JW0|rcsb pdb:5HPK|reactome:R-HSA-162588|reactome:R-HSA-2173788|reactome:R-HSA-2173795|reactome:R-HSA-2672351|reactome:R-HSA-983168|mint:Q96PU5|dip:DIP-41935N refseq:NP_444513.1|refseq:NP_001287783.1|ensembl:ENSG00000161634(gene)|ensembl:ENST00000293371(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008233"(peptidase activity)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR028130|interpro:IPR043557|mint:P81605|rcsb pdb:2KSG|rcsb pdb:2NDK|rcsb pdb:2YMK|rcsb pdb:6SHK|reactome:R-HSA-6803157 - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:HrKtKY/e1+GYwm5PbBxMO+7XOc09606 rogid:M8PkKVWx98nhtd79ods05mqw8Ls9606 rigid:/O+M6dQQVn+IyVuIxCueM/vqBgQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WX92 uniprotkb:Q01469 intact:EBI-347721|uniprotkb:Q96EW5|uniprotkb:Q9H9R4|uniprotkb:Q9ULN8|uniprotkb:Q9Y3W0|uniprotkb:A2BFA3|uniprotkb:A0A0X1KG71 intact:EBI-1054073|uniprotkb:B2R4K0|ensembl:ENSP00000297258 psi-mi:nelfb_human(display_long)|uniprotkb:NELFB(gene name)|psi-mi:NELFB(display_short)|uniprotkb:COBRA1(gene name synonym)|uniprotkb:Cofactor of BRCA1(gene name synonym)|uniprotkb:KIAA1182(gene name synonym) psi-mi:fabp5_human(display_long)|uniprotkb:Epidermal-type fatty acid-binding protein(gene name synonym)|uniprotkb:Psoriasis-associated fatty acid-binding protein homolog(gene name synonym)|uniprotkb:FABP5(gene name)|psi-mi:FABP5(display_short)|uniprotkb:Fatty acid-binding protein, epidermal(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481866|imex:IM-26985-191 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056271.3|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-9603505|reactome:R-HSA-167290|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008283"(cell population proliferation)|go:"GO:0032021"(NELF complex)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0048863"(stem cell differentiation)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR010405(Cofactor of BRCA1)|rcsb pdb:6GML|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|mint:Q8WX92|dip:DIP-32670N refseq:NP_001435.1|ensembl:ENSG00000164687(gene)|ensembl:ENST00000297258(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0008289"(lipid binding)|go:"GO:0008544"(epidermis development)|go:"GO:0010829"(negative regulation of glucose transmembrane transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031392"(regulation of prostaglandin biosynthetic process)|go:"GO:0035360"(positive regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099178"(regulation of retrograde trans-synaptic signaling by endocanabinoid)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990379"(lipid transport across blood-brain barrier)|interpro:IPR000463(Cytosolic fatty-acid binding)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR012674(Calycin)|interpro:IPR031259|mint:Q01469|rcsb pdb:1B56|rcsb pdb:1JJJ|rcsb pdb:4AZM|rcsb pdb:4AZR|rcsb pdb:4LKP|rcsb pdb:4LKT|rcsb pdb:5HZ5|rcsb pdb:5UR9|reactome:R-HSA-163560|reactome:R-HSA-5362517|reactome:R-HSA-6798695 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:riNpwaKKh9L9WBarWlYQrmWgrXY9606 rogid:vxp81/mezHcm5oo27QOmAM8Y5dI9606 rigid:4FdLoWWUTmVrxB7pUmqHPXpEYgI false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WX92 uniprotkb:Q07955 intact:EBI-347721|uniprotkb:Q96EW5|uniprotkb:Q9H9R4|uniprotkb:Q9ULN8|uniprotkb:Q9Y3W0|uniprotkb:A2BFA3|uniprotkb:A0A0X1KG71 intact:EBI-398920|uniprotkb:Q13809|uniprotkb:B2R6Z7|uniprotkb:D3DTZ3|ensembl:ENSP00000258962 psi-mi:nelfb_human(display_long)|uniprotkb:NELFB(gene name)|psi-mi:NELFB(display_short)|uniprotkb:COBRA1(gene name synonym)|uniprotkb:Cofactor of BRCA1(gene name synonym)|uniprotkb:KIAA1182(gene name synonym) psi-mi:srsf1_human(display_long)|uniprotkb:SF2(gene name synonym)|uniprotkb:SF2P33(gene name synonym)|uniprotkb:OK/SW-cl.3(orf name)|uniprotkb:SRSF1(gene name)|psi-mi:SRSF1(display_short)|uniprotkb:ASF(gene name synonym)|uniprotkb:pre-mRNA-splicing factor SF2, P33 subunit(gene name synonym)|uniprotkb:Alternative-splicing factor 1(gene name synonym)|uniprotkb:SFRS1(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481866|imex:IM-26985-191 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056271.3|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-9603505|reactome:R-HSA-167290|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008283"(cell population proliferation)|go:"GO:0032021"(NELF complex)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0048863"(stem cell differentiation)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR010405(Cofactor of BRCA1)|rcsb pdb:6GML|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|mint:Q8WX92|dip:DIP-32670N refseq:NP_001071634.1|refseq:NP_008855.1|dip:DIP-2155N|ensembl:ENSG00000136450(gene)|ensembl:ENST00000258962(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0051028"(mRNA transport)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097421"(liver regeneration)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034520|interpro:IPR035979|mint:Q07955|rcsb pdb:2M7S|rcsb pdb:2M8D|rcsb pdb:2O3D|rcsb pdb:3BEG|rcsb pdb:4C0O|rcsb pdb:6HPJ|rcsb pdb:7ABG|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:1X4A - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:riNpwaKKh9L9WBarWlYQrmWgrXY9606 rogid:6/IA4a3btkfSBtMH32iCe+rqZ8Y9606 rigid:4FdLoWWUTmVrxB7pUmqHPXpEYgI false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WX92 uniprotkb:P35030 intact:EBI-347721|uniprotkb:Q96EW5|uniprotkb:Q9H9R4|uniprotkb:Q9ULN8|uniprotkb:Q9Y3W0|uniprotkb:A2BFA3|uniprotkb:A0A0X1KG71 intact:EBI-1221209|uniprotkb:Q5VXV0|intact:EBI-2825937|uniprotkb:A8CED3|uniprotkb:F8W7P3|uniprotkb:Q6ISJ4|uniprotkb:P15951|uniprotkb:Q15665|uniprotkb:Q9UQV3|uniprotkb:A9Z1Y4|uniprotkb:E7ES07|uniprotkb:A8CED1 psi-mi:nelfb_human(display_long)|uniprotkb:NELFB(gene name)|psi-mi:NELFB(display_short)|uniprotkb:COBRA1(gene name synonym)|uniprotkb:Cofactor of BRCA1(gene name synonym)|uniprotkb:KIAA1182(gene name synonym) psi-mi:try3_human(display_long)|uniprotkb:PRSS3(gene name)|psi-mi:PRSS3(display_short)|uniprotkb:PRSS4(gene name synonym)|uniprotkb:TRY3(gene name synonym)|uniprotkb:TRY4(gene name synonym)|uniprotkb:Trypsin III(gene name synonym)|uniprotkb:Brain trypsinogen(gene name synonym)|uniprotkb:Mesotrypsinogen(gene name synonym)|uniprotkb:Trypsin IV(gene name synonym)|uniprotkb:Serine protease 3(gene name synonym)|uniprotkb:Serine protease 4(gene name synonym)|uniprotkb:Mesotrypsin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481866|imex:IM-26985-191 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056271.3|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-9603505|reactome:R-HSA-167290|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008283"(cell population proliferation)|go:"GO:0032021"(NELF complex)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0048863"(stem cell differentiation)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR010405(Cofactor of BRCA1)|rcsb pdb:6GML|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|mint:Q8WX92|dip:DIP-32670N refseq:NP_002762.2|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|refseq:NP_001184026.2|refseq:NP_031369.2|refseq:NP_001184027.1|mint:P35030|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0007586"(digestion)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0031638"(zymogen activation)|go:"GO:0043542"(endothelial cell migration)|go:"GO:1904724"(tertiary granule lumen)|rcsb pdb:1H4W|rcsb pdb:2R9P|rcsb pdb:3L33|rcsb pdb:3L3T|rcsb pdb:3P92|rcsb pdb:3P95|rcsb pdb:4DG4|rcsb pdb:4U30|rcsb pdb:4U32|rcsb pdb:5C67|rcsb pdb:5JBT|rcsb pdb:5TP0|rcsb pdb:6BX8|rcsb pdb:6GFI|reactome:R-HSA-1462054|reactome:R-HSA-196741|reactome:R-HSA-6798695|reactome:R-HSA-6803157|interpro:IPR043504 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:riNpwaKKh9L9WBarWlYQrmWgrXY9606 rogid:AEfz7orXeNoasizB5N76AkF4WMk9606 rigid:4FdLoWWUTmVrxB7pUmqHPXpEYgI false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXH7 uniprotkb:Q01469 intact:EBI-536725|uniprotkb:Q9BYL2|uniprotkb:Q9H405|uniprotkb:Q9H888|uniprotkb:Q9H8T3|uniprotkb:Q9NVX5|uniprotkb:Q9P029|uniprotkb:Q9UGN1|uniprotkb:Q9UGN2|uniprotkb:Q9UGN3|uniprotkb:B4DE06 intact:EBI-1054073|uniprotkb:B2R4K0|ensembl:ENSP00000297258 psi-mi:nelfd_human(display_long)|uniprotkb:NELFCD(gene name)|psi-mi:NELFCD(display_short)|uniprotkb:NELFD(gene name synonym)|uniprotkb:TH1(gene name synonym)|uniprotkb:TH1-like protein(gene name synonym)|uniprotkb:TH1L(gene name synonym)|uniprotkb:HSPC130(orf name) psi-mi:fabp5_human(display_long)|uniprotkb:Epidermal-type fatty acid-binding protein(gene name synonym)|uniprotkb:Psoriasis-associated fatty acid-binding protein homolog(gene name synonym)|uniprotkb:FABP5(gene name)|psi-mi:FABP5(display_short)|uniprotkb:Fatty acid-binding protein, epidermal(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481881|imex:IM-26985-557 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0032021"(NELF complex)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR006942(TH1 protein)|rcsb pdb:5L3X|rcsb pdb:6GML|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|refseq:NP_945327.2|mint:Q8IXH7|dip:DIP-34061N refseq:NP_001435.1|ensembl:ENSG00000164687(gene)|ensembl:ENST00000297258(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0008289"(lipid binding)|go:"GO:0008544"(epidermis development)|go:"GO:0010829"(negative regulation of glucose transmembrane transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031392"(regulation of prostaglandin biosynthetic process)|go:"GO:0035360"(positive regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099178"(regulation of retrograde trans-synaptic signaling by endocanabinoid)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990379"(lipid transport across blood-brain barrier)|interpro:IPR000463(Cytosolic fatty-acid binding)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR012674(Calycin)|interpro:IPR031259|mint:Q01469|rcsb pdb:1B56|rcsb pdb:1JJJ|rcsb pdb:4AZM|rcsb pdb:4AZR|rcsb pdb:4LKP|rcsb pdb:4LKT|rcsb pdb:5HZ5|rcsb pdb:5UR9|reactome:R-HSA-163560|reactome:R-HSA-5362517|reactome:R-HSA-6798695 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5x+m/j9x6zagup2Ptb1uFoNtDUE9606 rogid:vxp81/mezHcm5oo27QOmAM8Y5dI9606 rigid:nqgoAWO5/F/doNVgzy7tH/zKUv4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXH7 uniprotkb:P68363 intact:EBI-536725|uniprotkb:Q9BYL2|uniprotkb:Q9H405|uniprotkb:Q9H888|uniprotkb:Q9H8T3|uniprotkb:Q9NVX5|uniprotkb:Q9P029|uniprotkb:Q9UGN1|uniprotkb:Q9UGN2|uniprotkb:Q9UGN3|uniprotkb:B4DE06 intact:EBI-487083|intact:EBI-1384226|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:Q27I68|ensembl:ENSP00000336799|uniprotkb:Q8WU19 psi-mi:nelfd_human(display_long)|uniprotkb:NELFCD(gene name)|psi-mi:NELFCD(display_short)|uniprotkb:NELFD(gene name synonym)|uniprotkb:TH1(gene name synonym)|uniprotkb:TH1-like protein(gene name synonym)|uniprotkb:TH1L(gene name synonym)|uniprotkb:HSPC130(orf name) psi-mi:tba1b_human(display_long)|uniprotkb:TUBA1B(gene name)|psi-mi:TUBA1B(display_short)|uniprotkb:Tubulin alpha-ubiquitous chain(gene name synonym)|uniprotkb:Alpha-tubulin ubiquitous(gene name synonym)|uniprotkb:Tubulin K-alpha-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481881|imex:IM-26985-557 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0032021"(NELF complex)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR006942(TH1 protein)|rcsb pdb:5L3X|rcsb pdb:6GML|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|refseq:NP_945327.2|mint:Q8IXH7|dip:DIP-34061N refseq:NP_006073.2|ensembl:ENSG00000123416(gene)|ensembl:ENST00000336023(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-983189|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|go:"GO:0045121"(membrane raft)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68363|rcsb pdb:2E4H|rcsb pdb:5IJ0|rcsb pdb:5IJ9|rcsb pdb:5N5N|rcsb pdb:6E7B|rcsb pdb:6E7C|rcsb pdb:6I2I|go:"GO:0051301"(cell division)|rcsb pdb:6J4V|rcsb pdb:6J8O|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|rcsb pdb:6S8L|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9013407|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-2132295|reactome:R-HSA-9668328 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5x+m/j9x6zagup2Ptb1uFoNtDUE9606 rogid:D4YpuLCXl/S+53qV7P7sF81aARY9606 rigid:nqgoAWO5/F/doNVgzy7tH/zKUv4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXH7 uniprotkb:P16403 intact:EBI-536725|uniprotkb:Q9BYL2|uniprotkb:Q9H405|uniprotkb:Q9H888|uniprotkb:Q9H8T3|uniprotkb:Q9NVX5|uniprotkb:Q9P029|uniprotkb:Q9UGN1|uniprotkb:Q9UGN2|uniprotkb:Q9UGN3|uniprotkb:B4DE06 intact:EBI-358372|ensembl:ENSP00000339566|uniprotkb:A8K4I2 psi-mi:nelfd_human(display_long)|uniprotkb:NELFCD(gene name)|psi-mi:NELFCD(display_short)|uniprotkb:NELFD(gene name synonym)|uniprotkb:TH1(gene name synonym)|uniprotkb:TH1-like protein(gene name synonym)|uniprotkb:TH1L(gene name synonym)|uniprotkb:HSPC130(orf name) psi-mi:h12_human(display_long)|uniprotkb:H1-2(gene name)|psi-mi:H1-2(display_short)|uniprotkb:H1F2(gene name synonym)|uniprotkb:HIST1H1C(gene name synonym)|uniprotkb:Histone H1c(gene name synonym)|uniprotkb:Histone H1d(gene name synonym)|uniprotkb:Histone H1s-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481881|imex:IM-26985-557 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0032021"(NELF complex)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR006942(TH1 protein)|rcsb pdb:5L3X|rcsb pdb:6GML|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|refseq:NP_945327.2|mint:Q8IXH7|dip:DIP-34061N refseq:NP_005310.1|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P16403|reactome:R-HSA-140342|reactome:R-HSA-2559584|ensembl:ENSG00000187837(gene)|ensembl:ENST00000343677(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|dip:DIP-36359N - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5x+m/j9x6zagup2Ptb1uFoNtDUE9606 rogid:eRT5bTyBJUg6nRANMRYZekT4N+g9606 rigid:nqgoAWO5/F/doNVgzy7tH/zKUv4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXH7 uniprotkb:Q13247 intact:EBI-536725|uniprotkb:Q9BYL2|uniprotkb:Q9H405|uniprotkb:Q9H888|uniprotkb:Q9H8T3|uniprotkb:Q9NVX5|uniprotkb:Q9P029|uniprotkb:Q9UGN1|uniprotkb:Q9UGN2|uniprotkb:Q9UGN3|uniprotkb:B4DE06 intact:EBI-745230|uniprotkb:Q13244|uniprotkb:Q13245|uniprotkb:Q96J06|uniprotkb:Q9UJB8|uniprotkb:Q9Y3N7|uniprotkb:B7Z6J3|uniprotkb:E1P5W6|ensembl:ENSP00000244020 psi-mi:nelfd_human(display_long)|uniprotkb:NELFCD(gene name)|psi-mi:NELFCD(display_short)|uniprotkb:NELFD(gene name synonym)|uniprotkb:TH1(gene name synonym)|uniprotkb:TH1-like protein(gene name synonym)|uniprotkb:TH1L(gene name synonym)|uniprotkb:HSPC130(orf name) psi-mi:srsf6_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SRP55(gene name synonym)|uniprotkb:SRSF6(gene name)|psi-mi:SRSF6(display_short)|uniprotkb:SRP55(gene name synonym)|uniprotkb:SFRS6(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481881|imex:IM-26985-557 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0032021"(NELF complex)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR006942(TH1 protein)|rcsb pdb:5L3X|rcsb pdb:6GML|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|refseq:NP_945327.2|mint:Q8IXH7|dip:DIP-34061N refseq:NP_006266.2|ensembl:ENSG00000124193(gene)|ensembl:ENST00000244020(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0032868"(response to insulin)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0045617"(negative regulation of keratinocyte differentiation)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0060501"(positive regulation of epithelial cell proliferation involved in lung morphogenesis)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061041"(regulation of wound healing)|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029541|interpro:IPR034511|interpro:IPR035979|mint:Q13247|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5x+m/j9x6zagup2Ptb1uFoNtDUE9606 rogid:vU4nobP3g/hsgnll0mQgjJcME2k9606 rigid:nqgoAWO5/F/doNVgzy7tH/zKUv4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXH7 uniprotkb:P35030 intact:EBI-536725|uniprotkb:Q9BYL2|uniprotkb:Q9H405|uniprotkb:Q9H888|uniprotkb:Q9H8T3|uniprotkb:Q9NVX5|uniprotkb:Q9P029|uniprotkb:Q9UGN1|uniprotkb:Q9UGN2|uniprotkb:Q9UGN3|uniprotkb:B4DE06 intact:EBI-1221209|uniprotkb:Q5VXV0|intact:EBI-2825937|uniprotkb:A8CED3|uniprotkb:F8W7P3|uniprotkb:Q6ISJ4|uniprotkb:P15951|uniprotkb:Q15665|uniprotkb:Q9UQV3|uniprotkb:A9Z1Y4|uniprotkb:E7ES07|uniprotkb:A8CED1 psi-mi:nelfd_human(display_long)|uniprotkb:NELFCD(gene name)|psi-mi:NELFCD(display_short)|uniprotkb:NELFD(gene name synonym)|uniprotkb:TH1(gene name synonym)|uniprotkb:TH1-like protein(gene name synonym)|uniprotkb:TH1L(gene name synonym)|uniprotkb:HSPC130(orf name) psi-mi:try3_human(display_long)|uniprotkb:PRSS3(gene name)|psi-mi:PRSS3(display_short)|uniprotkb:PRSS4(gene name synonym)|uniprotkb:TRY3(gene name synonym)|uniprotkb:TRY4(gene name synonym)|uniprotkb:Trypsin III(gene name synonym)|uniprotkb:Brain trypsinogen(gene name synonym)|uniprotkb:Mesotrypsinogen(gene name synonym)|uniprotkb:Trypsin IV(gene name synonym)|uniprotkb:Serine protease 3(gene name synonym)|uniprotkb:Serine protease 4(gene name synonym)|uniprotkb:Mesotrypsin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481881|imex:IM-26985-557 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0032021"(NELF complex)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR006942(TH1 protein)|rcsb pdb:5L3X|rcsb pdb:6GML|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|refseq:NP_945327.2|mint:Q8IXH7|dip:DIP-34061N refseq:NP_002762.2|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|refseq:NP_001184026.2|refseq:NP_031369.2|refseq:NP_001184027.1|mint:P35030|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0007586"(digestion)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0031638"(zymogen activation)|go:"GO:0043542"(endothelial cell migration)|go:"GO:1904724"(tertiary granule lumen)|rcsb pdb:1H4W|rcsb pdb:2R9P|rcsb pdb:3L33|rcsb pdb:3L3T|rcsb pdb:3P92|rcsb pdb:3P95|rcsb pdb:4DG4|rcsb pdb:4U30|rcsb pdb:4U32|rcsb pdb:5C67|rcsb pdb:5JBT|rcsb pdb:5TP0|rcsb pdb:6BX8|rcsb pdb:6GFI|reactome:R-HSA-1462054|reactome:R-HSA-196741|reactome:R-HSA-6798695|reactome:R-HSA-6803157|interpro:IPR043504 - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5x+m/j9x6zagup2Ptb1uFoNtDUE9606 rogid:AEfz7orXeNoasizB5N76AkF4WMk9606 rigid:nqgoAWO5/F/doNVgzy7tH/zKUv4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXH7 uniprotkb:Q07955 intact:EBI-536725|uniprotkb:Q9BYL2|uniprotkb:Q9H405|uniprotkb:Q9H888|uniprotkb:Q9H8T3|uniprotkb:Q9NVX5|uniprotkb:Q9P029|uniprotkb:Q9UGN1|uniprotkb:Q9UGN2|uniprotkb:Q9UGN3|uniprotkb:B4DE06 intact:EBI-398920|uniprotkb:Q13809|uniprotkb:B2R6Z7|uniprotkb:D3DTZ3|ensembl:ENSP00000258962 psi-mi:nelfd_human(display_long)|uniprotkb:NELFCD(gene name)|psi-mi:NELFCD(display_short)|uniprotkb:NELFD(gene name synonym)|uniprotkb:TH1(gene name synonym)|uniprotkb:TH1-like protein(gene name synonym)|uniprotkb:TH1L(gene name synonym)|uniprotkb:HSPC130(orf name) psi-mi:srsf1_human(display_long)|uniprotkb:SF2(gene name synonym)|uniprotkb:SF2P33(gene name synonym)|uniprotkb:OK/SW-cl.3(orf name)|uniprotkb:SRSF1(gene name)|psi-mi:SRSF1(display_short)|uniprotkb:ASF(gene name synonym)|uniprotkb:pre-mRNA-splicing factor SF2, P33 subunit(gene name synonym)|uniprotkb:Alternative-splicing factor 1(gene name synonym)|uniprotkb:SFRS1(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481881|imex:IM-26985-557 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0032021"(NELF complex)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR006942(TH1 protein)|rcsb pdb:5L3X|rcsb pdb:6GML|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|refseq:NP_945327.2|mint:Q8IXH7|dip:DIP-34061N refseq:NP_001071634.1|refseq:NP_008855.1|dip:DIP-2155N|ensembl:ENSG00000136450(gene)|ensembl:ENST00000258962(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0051028"(mRNA transport)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097421"(liver regeneration)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034520|interpro:IPR035979|mint:Q07955|rcsb pdb:2M7S|rcsb pdb:2M8D|rcsb pdb:2O3D|rcsb pdb:3BEG|rcsb pdb:4C0O|rcsb pdb:6HPJ|rcsb pdb:7ABG|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:1X4A - - comment:"author score: 27" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5x+m/j9x6zagup2Ptb1uFoNtDUE9606 rogid:6/IA4a3btkfSBtMH32iCe+rqZ8Y9606 rigid:nqgoAWO5/F/doNVgzy7tH/zKUv4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXH7 uniprotkb:Q9H3P2 intact:EBI-536725|uniprotkb:Q9BYL2|uniprotkb:Q9H405|uniprotkb:Q9H888|uniprotkb:Q9H8T3|uniprotkb:Q9NVX5|uniprotkb:Q9P029|uniprotkb:Q9UGN1|uniprotkb:Q9UGN2|uniprotkb:Q9UGN3|uniprotkb:B4DE06 intact:EBI-5461341|uniprotkb:A2A2T1|uniprotkb:O95392|ensembl:ENSP00000372335 psi-mi:nelfd_human(display_long)|uniprotkb:NELFCD(gene name)|psi-mi:NELFCD(display_short)|uniprotkb:NELFD(gene name synonym)|uniprotkb:TH1(gene name synonym)|uniprotkb:TH1-like protein(gene name synonym)|uniprotkb:TH1L(gene name synonym)|uniprotkb:HSPC130(orf name) psi-mi:nelfa_human(display_long)|uniprotkb:NELFA(gene name)|psi-mi:NELFA(display_short)|uniprotkb:WHSC2(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 2 protein(gene name synonym)|uniprotkb:P/OKcl.15(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481881|imex:IM-26985-557 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0032021"(NELF complex)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR006942(TH1 protein)|rcsb pdb:5L3X|rcsb pdb:6GML|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|refseq:NP_945327.2|mint:Q8IXH7|dip:DIP-34061N refseq:NP_005654.3|dip:DIP-48478N|ensembl:ENSP00000372335|reactome:R-HSA-75955|ensembl:ENSG00000185049(gene)|ensembl:ENST00000382882(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007275"(multicellular organism development)|go:"GO:0016604"(nuclear body)|go:"GO:0032021"(NELF complex)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR037517|mint:Q9H3P2|rcsb pdb:5L3X|rcsb pdb:6GML|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|go:"GO:0051571"(positive regulation of histone H3-K4 methylation) - - comment:"author score: 73" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5x+m/j9x6zagup2Ptb1uFoNtDUE9606 rogid:5p43n+2CBfrTYOtRcnBf13uqM0o9606 rigid:nqgoAWO5/F/doNVgzy7tH/zKUv4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXH7 uniprotkb:Q8WX92 intact:EBI-536725|uniprotkb:Q9BYL2|uniprotkb:Q9H405|uniprotkb:Q9H888|uniprotkb:Q9H8T3|uniprotkb:Q9NVX5|uniprotkb:Q9P029|uniprotkb:Q9UGN1|uniprotkb:Q9UGN2|uniprotkb:Q9UGN3|uniprotkb:B4DE06 intact:EBI-347721|uniprotkb:Q96EW5|uniprotkb:Q9H9R4|uniprotkb:Q9ULN8|uniprotkb:Q9Y3W0|uniprotkb:A2BFA3|uniprotkb:A0A0X1KG71 psi-mi:nelfd_human(display_long)|uniprotkb:NELFCD(gene name)|psi-mi:NELFCD(display_short)|uniprotkb:NELFD(gene name synonym)|uniprotkb:TH1(gene name synonym)|uniprotkb:TH1-like protein(gene name synonym)|uniprotkb:TH1L(gene name synonym)|uniprotkb:HSPC130(orf name) psi-mi:nelfb_human(display_long)|uniprotkb:NELFB(gene name)|psi-mi:NELFB(display_short)|uniprotkb:COBRA1(gene name synonym)|uniprotkb:Cofactor of BRCA1(gene name synonym)|uniprotkb:KIAA1182(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481881|imex:IM-26985-557 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0032021"(NELF complex)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR006942(TH1 protein)|rcsb pdb:5L3X|rcsb pdb:6GML|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|refseq:NP_945327.2|mint:Q8IXH7|dip:DIP-34061N refseq:NP_056271.3|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-9603505|reactome:R-HSA-167290|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008283"(cell population proliferation)|go:"GO:0032021"(NELF complex)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0048863"(stem cell differentiation)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR010405(Cofactor of BRCA1)|rcsb pdb:6GML|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|mint:Q8WX92|dip:DIP-32670N - - comment:"author score: 99" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5x+m/j9x6zagup2Ptb1uFoNtDUE9606 rogid:riNpwaKKh9L9WBarWlYQrmWgrXY9606 rigid:nqgoAWO5/F/doNVgzy7tH/zKUv4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXH7 uniprotkb:P18615 intact:EBI-536725|uniprotkb:Q9BYL2|uniprotkb:Q9H405|uniprotkb:Q9H888|uniprotkb:Q9H8T3|uniprotkb:Q9NVX5|uniprotkb:Q9P029|uniprotkb:Q9UGN1|uniprotkb:Q9UGN2|uniprotkb:Q9UGN3|uniprotkb:B4DE06 intact:EBI-348444|uniprotkb:B4DUN1|uniprotkb:B4DYX9|ensembl:ENSP00000364578|ensembl:ENSP00000372660|ensembl:ENSP00000372834|ensembl:ENSP00000393005|ensembl:ENSP00000394879|ensembl:ENSP00000403623|uniprotkb:Q5JP74|uniprotkb:Q5JP75|uniprotkb:Q96F56|uniprotkb:Q9NPK2|uniprotkb:A2BE08 psi-mi:nelfd_human(display_long)|uniprotkb:NELFCD(gene name)|psi-mi:NELFCD(display_short)|uniprotkb:NELFD(gene name synonym)|uniprotkb:TH1(gene name synonym)|uniprotkb:TH1-like protein(gene name synonym)|uniprotkb:TH1L(gene name synonym)|uniprotkb:HSPC130(orf name) psi-mi:nelfe_human(display_long)|uniprotkb:NELFE(gene name)|psi-mi:NELFE(display_short)|uniprotkb:RD(gene name synonym)|uniprotkb:RDBP(gene name synonym)|uniprotkb:RNA-binding protein RD(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481881|imex:IM-26985-557 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0032021"(NELF complex)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|interpro:IPR006942(TH1 protein)|rcsb pdb:5L3X|rcsb pdb:6GML|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|refseq:NP_945327.2|mint:Q8IXH7|dip:DIP-34061N refseq:NP_002895.3|ensembl:ENSG00000204356(gene)|ensembl:ENSG00000206268(gene)|ensembl:ENSG00000206357(gene)|ensembl:ENSG00000229363(gene)|ensembl:ENSG00000231044(gene)|ensembl:ENSG00000233801(gene)|ensembl:ENST00000375429(transcript)|ensembl:ENST00000383174(transcript)|ensembl:ENST00000383343(transcript)|ensembl:ENST00000429857(transcript)|ensembl:ENST00000448628(transcript)|ensembl:ENST00000457397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0032021"(NELF complex)|go:"GO:0005634"(nucleus)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033102|interpro:IPR034637|interpro:IPR035979|mint:P18615|rcsb pdb:1X5P|rcsb pdb:2BZ2|rcsb pdb:2JX2|rcsb pdb:5OOB|rcsb pdb:6GML|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|dip:DIP-32669N - - comment:"author score: 99" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5x+m/j9x6zagup2Ptb1uFoNtDUE9606 rogid:AaBoPxRk9kFoijQiehOZtEZ+/OI9606 rigid:nqgoAWO5/F/doNVgzy7tH/zKUv4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35240 uniprotkb:P62750 intact:EBI-1014472|uniprotkb:O95683|uniprotkb:Q8WUJ2|uniprotkb:Q969N0|uniprotkb:Q969Q3|uniprotkb:Q96T30|uniprotkb:Q96T31|uniprotkb:Q96T32|uniprotkb:Q96T33|uniprotkb:Q9BTW3|uniprotkb:Q9UNG9|uniprotkb:Q9UNH3|uniprotkb:Q9UNH4|ensembl:ENSP00000344666 intact:EBI-353254|uniprotkb:P29316|uniprotkb:Q92774|uniprotkb:P39024|uniprotkb:B2R5B2|ensembl:ENSP00000389103 psi-mi:merl_human(display_long)|uniprotkb:Moesin-ezrin-radixin-like protein(gene name synonym)|uniprotkb:Neurofibromin-2(gene name synonym)|uniprotkb:Schwannomin(gene name synonym)|uniprotkb:Schwannomerlin(gene name synonym)|uniprotkb:NF2(gene name)|psi-mi:NF2(display_short)|uniprotkb:SCH(gene name synonym) psi-mi:rl23a_human(display_long)|uniprotkb:RPL23A(gene name)|psi-mi:RPL23A(display_short)|uniprotkb:Large ribosomal subunit protein uL23(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481947|imex:IM-26985-193 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000259.1|refseq:NP_057502.2|refseq:NP_861546.1|refseq:NP_861966.1|refseq:NP_861967.1|refseq:NP_861968.1|refseq:NP_861969.1|refseq:NP_861970.1|refseq:NP_861971.1|ensembl:ENSG00000186575(gene)|ensembl:ENST00000338641(transcript)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007398"(ectoderm development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014010"(Schwann cell proliferation)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0016020"(membrane)|go:"GO:0021766"(hippocampus development)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035330"(regulation of hippo signaling)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044297"(cell body)|go:"GO:0045177"(apical part of cell)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|mint:P35240|rcsb pdb:1H4R|rcsb pdb:3U8Z|rcsb pdb:4ZRI|rcsb pdb:4ZRJ|rcsb pdb:6CDS|reactome:R-HSA-2029482|reactome:R-HSA-5627123|dip:DIP-35389N reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|refseq:NP_000975.2|ensembl:ENSG00000198242(gene)|ensembl:ENST00000422514(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904841"(TORC2 complex binding)|interpro:IPR001014(Ribosomal protein L23, conserved site)|interpro:IPR005633(Ribosomal protein L23/L25, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR013025(Ribosomal protein L25/L23)|interpro:IPR019985|mint:P62750|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:YyzGKX6SmAvbiIgejNTvu/64uXc9606 rogid:lA1ubRFO9/Tl54Z1dKUzoCKvpAo9606 rigid:LYRDZgW86aLdZ/ijw4xojf68Ic4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35240 uniprotkb:Q9H7H0 intact:EBI-1014472|uniprotkb:O95683|uniprotkb:Q8WUJ2|uniprotkb:Q969N0|uniprotkb:Q969Q3|uniprotkb:Q96T30|uniprotkb:Q96T31|uniprotkb:Q96T32|uniprotkb:Q96T33|uniprotkb:Q9BTW3|uniprotkb:Q9UNG9|uniprotkb:Q9UNH3|uniprotkb:Q9UNH4|ensembl:ENSP00000344666 intact:EBI-749353|intact:EBI-948255|uniprotkb:Q9BSH1|uniprotkb:Q9BZH2|uniprotkb:Q9BZH3|ensembl:ENSP00000343041 psi-mi:merl_human(display_long)|uniprotkb:Moesin-ezrin-radixin-like protein(gene name synonym)|uniprotkb:Neurofibromin-2(gene name synonym)|uniprotkb:Schwannomin(gene name synonym)|uniprotkb:Schwannomerlin(gene name synonym)|uniprotkb:NF2(gene name)|psi-mi:NF2(display_short)|uniprotkb:SCH(gene name synonym) psi-mi:met17_human(display_long)|uniprotkb:METT11D1(gene name synonym)|uniprotkb:Protein RSM22 homolog, mitochondrial(gene name synonym)|uniprotkb:METTL17(gene name)|psi-mi:METTL17(display_short)|uniprotkb:Methyltransferase 11 domain-containing protein 1(gene name synonym)|uniprotkb:False p73 target gene protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481947|imex:IM-26985-193 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000259.1|refseq:NP_057502.2|refseq:NP_861546.1|refseq:NP_861966.1|refseq:NP_861967.1|refseq:NP_861968.1|refseq:NP_861969.1|refseq:NP_861970.1|refseq:NP_861971.1|ensembl:ENSG00000186575(gene)|ensembl:ENST00000338641(transcript)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007398"(ectoderm development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014010"(Schwann cell proliferation)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0016020"(membrane)|go:"GO:0021766"(hippocampus development)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035330"(regulation of hippo signaling)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044297"(cell body)|go:"GO:0045177"(apical part of cell)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|mint:P35240|rcsb pdb:1H4R|rcsb pdb:3U8Z|rcsb pdb:4ZRI|rcsb pdb:4ZRJ|rcsb pdb:6CDS|reactome:R-HSA-2029482|reactome:R-HSA-5627123|dip:DIP-35389N refseq:NP_001025162.1|refseq:NP_073571.1|ensembl:ENSG00000165792(gene)|ensembl:ENST00000339374(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006412"(translation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0032259"(methylation)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR015324(Ribosomal protein Rsm22, bacterial-type)|interpro:IPR029063|mint:Q9H7H0 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:YyzGKX6SmAvbiIgejNTvu/64uXc9606 rogid:RAj8jOqwthd7a0Xzi5FWhVKc8OI9606 rigid:LYRDZgW86aLdZ/ijw4xojf68Ic4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35240 uniprotkb:Q8IY63 intact:EBI-1014472|uniprotkb:O95683|uniprotkb:Q8WUJ2|uniprotkb:Q969N0|uniprotkb:Q969Q3|uniprotkb:Q96T30|uniprotkb:Q96T31|uniprotkb:Q96T32|uniprotkb:Q96T33|uniprotkb:Q9BTW3|uniprotkb:Q9UNG9|uniprotkb:Q9UNH3|uniprotkb:Q9UNH4|ensembl:ENSP00000344666 intact:EBI-1057112|uniprotkb:Q63HK7|uniprotkb:Q8NDN0|uniprotkb:Q8WXD1|uniprotkb:Q96CM5|intact:EBI-2514012|uniprotkb:Q8TEN8|intact:EBI-28986258|ensembl:ENSP00000387739 psi-mi:merl_human(display_long)|uniprotkb:Moesin-ezrin-radixin-like protein(gene name synonym)|uniprotkb:Neurofibromin-2(gene name synonym)|uniprotkb:Schwannomin(gene name synonym)|uniprotkb:Schwannomerlin(gene name synonym)|uniprotkb:NF2(gene name)|psi-mi:NF2(display_short)|uniprotkb:SCH(gene name synonym) psi-mi:amol1_human(display_long)|uniprotkb:AMOTL1(gene name)|psi-mi:AMOTL1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481947|imex:IM-26985-193 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000259.1|refseq:NP_057502.2|refseq:NP_861546.1|refseq:NP_861966.1|refseq:NP_861967.1|refseq:NP_861968.1|refseq:NP_861969.1|refseq:NP_861970.1|refseq:NP_861971.1|ensembl:ENSG00000186575(gene)|ensembl:ENST00000338641(transcript)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007398"(ectoderm development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014010"(Schwann cell proliferation)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0016020"(membrane)|go:"GO:0021766"(hippocampus development)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035330"(regulation of hippo signaling)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044297"(cell body)|go:"GO:0045177"(apical part of cell)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|mint:P35240|rcsb pdb:1H4R|rcsb pdb:3U8Z|rcsb pdb:4ZRI|rcsb pdb:4ZRJ|rcsb pdb:6CDS|reactome:R-HSA-2029482|reactome:R-HSA-5627123|dip:DIP-35389N refseq:NP_001287936.1|refseq:NP_570899.1|ensembl:ENST00000317829|ensembl:ENSP00000320968|ensembl:ENSP00000387739|ensembl:ENSG00000166025(gene)|ensembl:ENST00000433060(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035329"(hippo signaling)|go:"GO:0042802"(identical protein binding)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q8IY63|reactome:R-HSA-2028269|dip:DIP-50682N - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:YyzGKX6SmAvbiIgejNTvu/64uXc9606 rogid:yveF+96pkmFC0XntrVNmwhrVzK09606 rigid:LYRDZgW86aLdZ/ijw4xojf68Ic4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35240 uniprotkb:Q969Q0 intact:EBI-1014472|uniprotkb:O95683|uniprotkb:Q8WUJ2|uniprotkb:Q969N0|uniprotkb:Q969Q3|uniprotkb:Q96T30|uniprotkb:Q96T31|uniprotkb:Q96T32|uniprotkb:Q96T33|uniprotkb:Q9BTW3|uniprotkb:Q9UNG9|uniprotkb:Q9UNH3|uniprotkb:Q9UNH4|ensembl:ENSP00000344666 intact:EBI-2877705|ensembl:ENSP00000346012|uniprotkb:Q3B7A5 psi-mi:merl_human(display_long)|uniprotkb:Moesin-ezrin-radixin-like protein(gene name synonym)|uniprotkb:Neurofibromin-2(gene name synonym)|uniprotkb:Schwannomin(gene name synonym)|uniprotkb:Schwannomerlin(gene name synonym)|uniprotkb:NF2(gene name)|psi-mi:NF2(display_short)|uniprotkb:SCH(gene name synonym) psi-mi:rl36l_human(display_long)|uniprotkb:RPL36AL(gene name)|psi-mi:RPL36AL(display_short)|uniprotkb:Large ribosomal subunit protein eL42-like(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481947|imex:IM-26985-193 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000259.1|refseq:NP_057502.2|refseq:NP_861546.1|refseq:NP_861966.1|refseq:NP_861967.1|refseq:NP_861968.1|refseq:NP_861969.1|refseq:NP_861970.1|refseq:NP_861971.1|ensembl:ENSG00000186575(gene)|ensembl:ENST00000338641(transcript)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007398"(ectoderm development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014010"(Schwann cell proliferation)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0016020"(membrane)|go:"GO:0021766"(hippocampus development)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035330"(regulation of hippo signaling)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044297"(cell body)|go:"GO:0045177"(apical part of cell)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|mint:P35240|rcsb pdb:1H4R|rcsb pdb:3U8Z|rcsb pdb:4ZRI|rcsb pdb:4ZRJ|rcsb pdb:6CDS|reactome:R-HSA-2029482|reactome:R-HSA-5627123|dip:DIP-35389N ensembl:ENSG00000165502(gene)|ensembl:ENST00000298289(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR000552(Ribosomal protein L44e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|mint:Q969Q0|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-9633012|refseq:NP_000992.1 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:YyzGKX6SmAvbiIgejNTvu/64uXc9606 rogid:+jT5oFy79StEavkvHz6j/36g/qg9606 rigid:LYRDZgW86aLdZ/ijw4xojf68Ic4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35240 uniprotkb:Q4VCS5 intact:EBI-1014472|uniprotkb:O95683|uniprotkb:Q8WUJ2|uniprotkb:Q969N0|uniprotkb:Q969Q3|uniprotkb:Q96T30|uniprotkb:Q96T31|uniprotkb:Q96T32|uniprotkb:Q96T33|uniprotkb:Q9BTW3|uniprotkb:Q9UNG9|uniprotkb:Q9UNH3|uniprotkb:Q9UNH4|ensembl:ENSP00000344666 intact:EBI-2511319|ensembl:ENSP00000361027|uniprotkb:Q504X5|uniprotkb:Q9UPT1|uniprotkb:Q9HD27 psi-mi:merl_human(display_long)|uniprotkb:Moesin-ezrin-radixin-like protein(gene name synonym)|uniprotkb:Neurofibromin-2(gene name synonym)|uniprotkb:Schwannomin(gene name synonym)|uniprotkb:Schwannomerlin(gene name synonym)|uniprotkb:NF2(gene name)|psi-mi:NF2(display_short)|uniprotkb:SCH(gene name synonym) psi-mi:amot_human(display_long)|uniprotkb:AMOT(gene name)|psi-mi:AMOT(display_short)|uniprotkb:KIAA1071(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481947|imex:IM-26985-193 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000259.1|refseq:NP_057502.2|refseq:NP_861546.1|refseq:NP_861966.1|refseq:NP_861967.1|refseq:NP_861968.1|refseq:NP_861969.1|refseq:NP_861970.1|refseq:NP_861971.1|ensembl:ENSG00000186575(gene)|ensembl:ENST00000338641(transcript)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007398"(ectoderm development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014010"(Schwann cell proliferation)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0016020"(membrane)|go:"GO:0021766"(hippocampus development)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035330"(regulation of hippo signaling)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044297"(cell body)|go:"GO:0045177"(apical part of cell)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|mint:P35240|rcsb pdb:1H4R|rcsb pdb:3U8Z|rcsb pdb:4ZRI|rcsb pdb:4ZRJ|rcsb pdb:6CDS|reactome:R-HSA-2029482|reactome:R-HSA-5627123|dip:DIP-35389N ensembl:ENSG00000126016(gene)|ensembl:ENST00000371959(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003365"(establishment of cell polarity involved in ameboidal cell migration)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006935"(chemotaxis)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035329"(hippo signaling)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0042074"(cell migration involved in gastrulation)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043532"(angiostatin binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051496"(positive regulation of stress fiber assembly)|interpro:IPR009114(Angiomotin)|interpro:IPR024646|mint:Q4VCS5|rcsb pdb:6JJX|reactome:R-HSA-2028269|refseq:XP_011529177.1|refseq:NP_001106962.1|refseq:NP_573572.1|refseq:XP_005262144.1|refseq:XP_005262147.1|refseq:XP_016884778.1|dip:DIP-53711N - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:YyzGKX6SmAvbiIgejNTvu/64uXc9606 rogid:5O9K+GgX1s0Hn5optTeKPOs+X1s9606 rigid:LYRDZgW86aLdZ/ijw4xojf68Ic4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P18615 uniprotkb:P16403 intact:EBI-348444|uniprotkb:B4DUN1|uniprotkb:B4DYX9|ensembl:ENSP00000364578|ensembl:ENSP00000372660|ensembl:ENSP00000372834|ensembl:ENSP00000393005|ensembl:ENSP00000394879|ensembl:ENSP00000403623|uniprotkb:Q5JP74|uniprotkb:Q5JP75|uniprotkb:Q96F56|uniprotkb:Q9NPK2|uniprotkb:A2BE08 intact:EBI-358372|ensembl:ENSP00000339566|uniprotkb:A8K4I2 psi-mi:nelfe_human(display_long)|uniprotkb:NELFE(gene name)|psi-mi:NELFE(display_short)|uniprotkb:RD(gene name synonym)|uniprotkb:RDBP(gene name synonym)|uniprotkb:RNA-binding protein RD(gene name synonym) psi-mi:h12_human(display_long)|uniprotkb:H1-2(gene name)|psi-mi:H1-2(display_short)|uniprotkb:H1F2(gene name synonym)|uniprotkb:HIST1H1C(gene name synonym)|uniprotkb:Histone H1c(gene name synonym)|uniprotkb:Histone H1d(gene name synonym)|uniprotkb:Histone H1s-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481917|imex:IM-26985-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002895.3|ensembl:ENSG00000204356(gene)|ensembl:ENSG00000206268(gene)|ensembl:ENSG00000206357(gene)|ensembl:ENSG00000229363(gene)|ensembl:ENSG00000231044(gene)|ensembl:ENSG00000233801(gene)|ensembl:ENST00000375429(transcript)|ensembl:ENST00000383174(transcript)|ensembl:ENST00000383343(transcript)|ensembl:ENST00000429857(transcript)|ensembl:ENST00000448628(transcript)|ensembl:ENST00000457397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0032021"(NELF complex)|go:"GO:0005634"(nucleus)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033102|interpro:IPR034637|interpro:IPR035979|mint:P18615|rcsb pdb:1X5P|rcsb pdb:2BZ2|rcsb pdb:2JX2|rcsb pdb:5OOB|rcsb pdb:6GML|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|dip:DIP-32669N refseq:NP_005310.1|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P16403|reactome:R-HSA-140342|reactome:R-HSA-2559584|ensembl:ENSG00000187837(gene)|ensembl:ENST00000343677(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|dip:DIP-36359N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:AaBoPxRk9kFoijQiehOZtEZ+/OI9606 rogid:eRT5bTyBJUg6nRANMRYZekT4N+g9606 rigid:JwXrBRAPjOtb6ozRzYuV9l84nME false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P18615 uniprotkb:Q01469 intact:EBI-348444|uniprotkb:B4DUN1|uniprotkb:B4DYX9|ensembl:ENSP00000364578|ensembl:ENSP00000372660|ensembl:ENSP00000372834|ensembl:ENSP00000393005|ensembl:ENSP00000394879|ensembl:ENSP00000403623|uniprotkb:Q5JP74|uniprotkb:Q5JP75|uniprotkb:Q96F56|uniprotkb:Q9NPK2|uniprotkb:A2BE08 intact:EBI-1054073|uniprotkb:B2R4K0|ensembl:ENSP00000297258 psi-mi:nelfe_human(display_long)|uniprotkb:NELFE(gene name)|psi-mi:NELFE(display_short)|uniprotkb:RD(gene name synonym)|uniprotkb:RDBP(gene name synonym)|uniprotkb:RNA-binding protein RD(gene name synonym) psi-mi:fabp5_human(display_long)|uniprotkb:Epidermal-type fatty acid-binding protein(gene name synonym)|uniprotkb:Psoriasis-associated fatty acid-binding protein homolog(gene name synonym)|uniprotkb:FABP5(gene name)|psi-mi:FABP5(display_short)|uniprotkb:Fatty acid-binding protein, epidermal(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481917|imex:IM-26985-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002895.3|ensembl:ENSG00000204356(gene)|ensembl:ENSG00000206268(gene)|ensembl:ENSG00000206357(gene)|ensembl:ENSG00000229363(gene)|ensembl:ENSG00000231044(gene)|ensembl:ENSG00000233801(gene)|ensembl:ENST00000375429(transcript)|ensembl:ENST00000383174(transcript)|ensembl:ENST00000383343(transcript)|ensembl:ENST00000429857(transcript)|ensembl:ENST00000448628(transcript)|ensembl:ENST00000457397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0032021"(NELF complex)|go:"GO:0005634"(nucleus)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033102|interpro:IPR034637|interpro:IPR035979|mint:P18615|rcsb pdb:1X5P|rcsb pdb:2BZ2|rcsb pdb:2JX2|rcsb pdb:5OOB|rcsb pdb:6GML|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|dip:DIP-32669N refseq:NP_001435.1|ensembl:ENSG00000164687(gene)|ensembl:ENST00000297258(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0008289"(lipid binding)|go:"GO:0008544"(epidermis development)|go:"GO:0010829"(negative regulation of glucose transmembrane transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031392"(regulation of prostaglandin biosynthetic process)|go:"GO:0035360"(positive regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099178"(regulation of retrograde trans-synaptic signaling by endocanabinoid)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990379"(lipid transport across blood-brain barrier)|interpro:IPR000463(Cytosolic fatty-acid binding)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR012674(Calycin)|interpro:IPR031259|mint:Q01469|rcsb pdb:1B56|rcsb pdb:1JJJ|rcsb pdb:4AZM|rcsb pdb:4AZR|rcsb pdb:4LKP|rcsb pdb:4LKT|rcsb pdb:5HZ5|rcsb pdb:5UR9|reactome:R-HSA-163560|reactome:R-HSA-5362517|reactome:R-HSA-6798695 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:AaBoPxRk9kFoijQiehOZtEZ+/OI9606 rogid:vxp81/mezHcm5oo27QOmAM8Y5dI9606 rigid:JwXrBRAPjOtb6ozRzYuV9l84nME false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P18615 uniprotkb:P23490 intact:EBI-348444|uniprotkb:B4DUN1|uniprotkb:B4DYX9|ensembl:ENSP00000364578|ensembl:ENSP00000372660|ensembl:ENSP00000372834|ensembl:ENSP00000393005|ensembl:ENSP00000394879|ensembl:ENSP00000403623|uniprotkb:Q5JP74|uniprotkb:Q5JP75|uniprotkb:Q96F56|uniprotkb:Q9NPK2|uniprotkb:A2BE08 intact:EBI-715902|uniprotkb:Q5T869|uniprotkb:Q5XKF8|ensembl:ENSP00000357731 psi-mi:nelfe_human(display_long)|uniprotkb:NELFE(gene name)|psi-mi:NELFE(display_short)|uniprotkb:RD(gene name synonym)|uniprotkb:RDBP(gene name synonym)|uniprotkb:RNA-binding protein RD(gene name synonym) psi-mi:lori_human(display_long)|uniprotkb:LORICRIN(gene name)|psi-mi:LORICRIN(display_short)|uniprotkb:LOR(gene name synonym)|uniprotkb:LRN(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481917|imex:IM-26985-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002895.3|ensembl:ENSG00000204356(gene)|ensembl:ENSG00000206268(gene)|ensembl:ENSG00000206357(gene)|ensembl:ENSG00000229363(gene)|ensembl:ENSG00000231044(gene)|ensembl:ENSG00000233801(gene)|ensembl:ENST00000375429(transcript)|ensembl:ENST00000383174(transcript)|ensembl:ENST00000383343(transcript)|ensembl:ENST00000429857(transcript)|ensembl:ENST00000448628(transcript)|ensembl:ENST00000457397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0032021"(NELF complex)|go:"GO:0005634"(nucleus)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033102|interpro:IPR034637|interpro:IPR035979|mint:P18615|rcsb pdb:1X5P|rcsb pdb:2BZ2|rcsb pdb:2JX2|rcsb pdb:5OOB|rcsb pdb:6GML|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|dip:DIP-32669N refseq:NP_000418.2|ensembl:ENSG00000203782(gene)|ensembl:ENST00000368742(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030280"(structural constituent of skin epidermis)|go:"GO:0031424"(keratinization)|interpro:IPR031700|mint:P23490|reactome:R-HSA-6809371 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:AaBoPxRk9kFoijQiehOZtEZ+/OI9606 rogid:ISIQk0W6vIOc/aityV1tebyaTE89606 rigid:JwXrBRAPjOtb6ozRzYuV9l84nME false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P18615 uniprotkb:Q5T750 intact:EBI-348444|uniprotkb:B4DUN1|uniprotkb:B4DYX9|ensembl:ENSP00000364578|ensembl:ENSP00000372660|ensembl:ENSP00000372834|ensembl:ENSP00000393005|ensembl:ENSP00000394879|ensembl:ENSP00000403623|uniprotkb:Q5JP74|uniprotkb:Q5JP75|uniprotkb:Q96F56|uniprotkb:Q9NPK2|uniprotkb:A2BE08 intact:EBI-2563033|ensembl:ENSP00000357764|uniprotkb:O14634 psi-mi:nelfe_human(display_long)|uniprotkb:NELFE(gene name)|psi-mi:NELFE(display_short)|uniprotkb:RD(gene name synonym)|uniprotkb:RDBP(gene name synonym)|uniprotkb:RNA-binding protein RD(gene name synonym) psi-mi:xp32_human(display_long)|uniprotkb:XP32(gene name)|psi-mi:XP32(display_short)|uniprotkb:C1orf68(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481917|imex:IM-26985-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002895.3|ensembl:ENSG00000204356(gene)|ensembl:ENSG00000206268(gene)|ensembl:ENSG00000206357(gene)|ensembl:ENSG00000229363(gene)|ensembl:ENSG00000231044(gene)|ensembl:ENSG00000233801(gene)|ensembl:ENST00000375429(transcript)|ensembl:ENST00000383174(transcript)|ensembl:ENST00000383343(transcript)|ensembl:ENST00000429857(transcript)|ensembl:ENST00000448628(transcript)|ensembl:ENST00000457397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0032021"(NELF complex)|go:"GO:0005634"(nucleus)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033102|interpro:IPR034637|interpro:IPR035979|mint:P18615|rcsb pdb:1X5P|rcsb pdb:2BZ2|rcsb pdb:2JX2|rcsb pdb:5OOB|rcsb pdb:6GML|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|dip:DIP-32669N refseq:NP_001019850.1|ensembl:ENSG00000198854(gene)|ensembl:ENST00000368775(transcript)|go:"GO:0008544"(epidermis development)|interpro:IPR026078|mint:Q5T750 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:AaBoPxRk9kFoijQiehOZtEZ+/OI9606 rogid:QHKngjyz/pqUrpu1XJ8NINDtmm49606 rigid:JwXrBRAPjOtb6ozRzYuV9l84nME false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P18615 uniprotkb:P35030 intact:EBI-348444|uniprotkb:B4DUN1|uniprotkb:B4DYX9|ensembl:ENSP00000364578|ensembl:ENSP00000372660|ensembl:ENSP00000372834|ensembl:ENSP00000393005|ensembl:ENSP00000394879|ensembl:ENSP00000403623|uniprotkb:Q5JP74|uniprotkb:Q5JP75|uniprotkb:Q96F56|uniprotkb:Q9NPK2|uniprotkb:A2BE08 intact:EBI-1221209|uniprotkb:Q5VXV0|intact:EBI-2825937|uniprotkb:A8CED3|uniprotkb:F8W7P3|uniprotkb:Q6ISJ4|uniprotkb:P15951|uniprotkb:Q15665|uniprotkb:Q9UQV3|uniprotkb:A9Z1Y4|uniprotkb:E7ES07|uniprotkb:A8CED1 psi-mi:nelfe_human(display_long)|uniprotkb:NELFE(gene name)|psi-mi:NELFE(display_short)|uniprotkb:RD(gene name synonym)|uniprotkb:RDBP(gene name synonym)|uniprotkb:RNA-binding protein RD(gene name synonym) psi-mi:try3_human(display_long)|uniprotkb:PRSS3(gene name)|psi-mi:PRSS3(display_short)|uniprotkb:PRSS4(gene name synonym)|uniprotkb:TRY3(gene name synonym)|uniprotkb:TRY4(gene name synonym)|uniprotkb:Trypsin III(gene name synonym)|uniprotkb:Brain trypsinogen(gene name synonym)|uniprotkb:Mesotrypsinogen(gene name synonym)|uniprotkb:Trypsin IV(gene name synonym)|uniprotkb:Serine protease 3(gene name synonym)|uniprotkb:Serine protease 4(gene name synonym)|uniprotkb:Mesotrypsin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481917|imex:IM-26985-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002895.3|ensembl:ENSG00000204356(gene)|ensembl:ENSG00000206268(gene)|ensembl:ENSG00000206357(gene)|ensembl:ENSG00000229363(gene)|ensembl:ENSG00000231044(gene)|ensembl:ENSG00000233801(gene)|ensembl:ENST00000375429(transcript)|ensembl:ENST00000383174(transcript)|ensembl:ENST00000383343(transcript)|ensembl:ENST00000429857(transcript)|ensembl:ENST00000448628(transcript)|ensembl:ENST00000457397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0032021"(NELF complex)|go:"GO:0005634"(nucleus)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033102|interpro:IPR034637|interpro:IPR035979|mint:P18615|rcsb pdb:1X5P|rcsb pdb:2BZ2|rcsb pdb:2JX2|rcsb pdb:5OOB|rcsb pdb:6GML|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|dip:DIP-32669N refseq:NP_002762.2|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|refseq:NP_001184026.2|refseq:NP_031369.2|refseq:NP_001184027.1|mint:P35030|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0007586"(digestion)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0031638"(zymogen activation)|go:"GO:0043542"(endothelial cell migration)|go:"GO:1904724"(tertiary granule lumen)|rcsb pdb:1H4W|rcsb pdb:2R9P|rcsb pdb:3L33|rcsb pdb:3L3T|rcsb pdb:3P92|rcsb pdb:3P95|rcsb pdb:4DG4|rcsb pdb:4U30|rcsb pdb:4U32|rcsb pdb:5C67|rcsb pdb:5JBT|rcsb pdb:5TP0|rcsb pdb:6BX8|rcsb pdb:6GFI|reactome:R-HSA-1462054|reactome:R-HSA-196741|reactome:R-HSA-6798695|reactome:R-HSA-6803157|interpro:IPR043504 - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:AaBoPxRk9kFoijQiehOZtEZ+/OI9606 rogid:AEfz7orXeNoasizB5N76AkF4WMk9606 rigid:JwXrBRAPjOtb6ozRzYuV9l84nME false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P18615 uniprotkb:Q07955 intact:EBI-348444|uniprotkb:B4DUN1|uniprotkb:B4DYX9|ensembl:ENSP00000364578|ensembl:ENSP00000372660|ensembl:ENSP00000372834|ensembl:ENSP00000393005|ensembl:ENSP00000394879|ensembl:ENSP00000403623|uniprotkb:Q5JP74|uniprotkb:Q5JP75|uniprotkb:Q96F56|uniprotkb:Q9NPK2|uniprotkb:A2BE08 intact:EBI-398920|uniprotkb:Q13809|uniprotkb:B2R6Z7|uniprotkb:D3DTZ3|ensembl:ENSP00000258962 psi-mi:nelfe_human(display_long)|uniprotkb:NELFE(gene name)|psi-mi:NELFE(display_short)|uniprotkb:RD(gene name synonym)|uniprotkb:RDBP(gene name synonym)|uniprotkb:RNA-binding protein RD(gene name synonym) psi-mi:srsf1_human(display_long)|uniprotkb:SF2(gene name synonym)|uniprotkb:SF2P33(gene name synonym)|uniprotkb:OK/SW-cl.3(orf name)|uniprotkb:SRSF1(gene name)|psi-mi:SRSF1(display_short)|uniprotkb:ASF(gene name synonym)|uniprotkb:pre-mRNA-splicing factor SF2, P33 subunit(gene name synonym)|uniprotkb:Alternative-splicing factor 1(gene name synonym)|uniprotkb:SFRS1(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481917|imex:IM-26985-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002895.3|ensembl:ENSG00000204356(gene)|ensembl:ENSG00000206268(gene)|ensembl:ENSG00000206357(gene)|ensembl:ENSG00000229363(gene)|ensembl:ENSG00000231044(gene)|ensembl:ENSG00000233801(gene)|ensembl:ENST00000375429(transcript)|ensembl:ENST00000383174(transcript)|ensembl:ENST00000383343(transcript)|ensembl:ENST00000429857(transcript)|ensembl:ENST00000448628(transcript)|ensembl:ENST00000457397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0032021"(NELF complex)|go:"GO:0005634"(nucleus)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033102|interpro:IPR034637|interpro:IPR035979|mint:P18615|rcsb pdb:1X5P|rcsb pdb:2BZ2|rcsb pdb:2JX2|rcsb pdb:5OOB|rcsb pdb:6GML|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|dip:DIP-32669N refseq:NP_001071634.1|refseq:NP_008855.1|dip:DIP-2155N|ensembl:ENSG00000136450(gene)|ensembl:ENST00000258962(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0051028"(mRNA transport)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097421"(liver regeneration)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034520|interpro:IPR035979|mint:Q07955|rcsb pdb:2M7S|rcsb pdb:2M8D|rcsb pdb:2O3D|rcsb pdb:3BEG|rcsb pdb:4C0O|rcsb pdb:6HPJ|rcsb pdb:7ABG|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:1X4A - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:AaBoPxRk9kFoijQiehOZtEZ+/OI9606 rogid:6/IA4a3btkfSBtMH32iCe+rqZ8Y9606 rigid:JwXrBRAPjOtb6ozRzYuV9l84nME false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P18615 uniprotkb:Q9H3P2 intact:EBI-348444|uniprotkb:B4DUN1|uniprotkb:B4DYX9|ensembl:ENSP00000364578|ensembl:ENSP00000372660|ensembl:ENSP00000372834|ensembl:ENSP00000393005|ensembl:ENSP00000394879|ensembl:ENSP00000403623|uniprotkb:Q5JP74|uniprotkb:Q5JP75|uniprotkb:Q96F56|uniprotkb:Q9NPK2|uniprotkb:A2BE08 intact:EBI-5461341|uniprotkb:A2A2T1|uniprotkb:O95392|ensembl:ENSP00000372335 psi-mi:nelfe_human(display_long)|uniprotkb:NELFE(gene name)|psi-mi:NELFE(display_short)|uniprotkb:RD(gene name synonym)|uniprotkb:RDBP(gene name synonym)|uniprotkb:RNA-binding protein RD(gene name synonym) psi-mi:nelfa_human(display_long)|uniprotkb:NELFA(gene name)|psi-mi:NELFA(display_short)|uniprotkb:WHSC2(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 2 protein(gene name synonym)|uniprotkb:P/OKcl.15(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481917|imex:IM-26985-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002895.3|ensembl:ENSG00000204356(gene)|ensembl:ENSG00000206268(gene)|ensembl:ENSG00000206357(gene)|ensembl:ENSG00000229363(gene)|ensembl:ENSG00000231044(gene)|ensembl:ENSG00000233801(gene)|ensembl:ENST00000375429(transcript)|ensembl:ENST00000383174(transcript)|ensembl:ENST00000383343(transcript)|ensembl:ENST00000429857(transcript)|ensembl:ENST00000448628(transcript)|ensembl:ENST00000457397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0032021"(NELF complex)|go:"GO:0005634"(nucleus)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033102|interpro:IPR034637|interpro:IPR035979|mint:P18615|rcsb pdb:1X5P|rcsb pdb:2BZ2|rcsb pdb:2JX2|rcsb pdb:5OOB|rcsb pdb:6GML|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|dip:DIP-32669N refseq:NP_005654.3|dip:DIP-48478N|ensembl:ENSP00000372335|reactome:R-HSA-75955|ensembl:ENSG00000185049(gene)|ensembl:ENST00000382882(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007275"(multicellular organism development)|go:"GO:0016604"(nuclear body)|go:"GO:0032021"(NELF complex)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR037517|mint:Q9H3P2|rcsb pdb:5L3X|rcsb pdb:6GML|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|go:"GO:0051571"(positive regulation of histone H3-K4 methylation) - - comment:"author score: 52" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:AaBoPxRk9kFoijQiehOZtEZ+/OI9606 rogid:5p43n+2CBfrTYOtRcnBf13uqM0o9606 rigid:JwXrBRAPjOtb6ozRzYuV9l84nME false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P18615 uniprotkb:Q8WX92 intact:EBI-348444|uniprotkb:B4DUN1|uniprotkb:B4DYX9|ensembl:ENSP00000364578|ensembl:ENSP00000372660|ensembl:ENSP00000372834|ensembl:ENSP00000393005|ensembl:ENSP00000394879|ensembl:ENSP00000403623|uniprotkb:Q5JP74|uniprotkb:Q5JP75|uniprotkb:Q96F56|uniprotkb:Q9NPK2|uniprotkb:A2BE08 intact:EBI-347721|uniprotkb:Q96EW5|uniprotkb:Q9H9R4|uniprotkb:Q9ULN8|uniprotkb:Q9Y3W0|uniprotkb:A2BFA3|uniprotkb:A0A0X1KG71 psi-mi:nelfe_human(display_long)|uniprotkb:NELFE(gene name)|psi-mi:NELFE(display_short)|uniprotkb:RD(gene name synonym)|uniprotkb:RDBP(gene name synonym)|uniprotkb:RNA-binding protein RD(gene name synonym) psi-mi:nelfb_human(display_long)|uniprotkb:NELFB(gene name)|psi-mi:NELFB(display_short)|uniprotkb:COBRA1(gene name synonym)|uniprotkb:Cofactor of BRCA1(gene name synonym)|uniprotkb:KIAA1182(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481917|imex:IM-26985-43 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002895.3|ensembl:ENSG00000204356(gene)|ensembl:ENSG00000206268(gene)|ensembl:ENSG00000206357(gene)|ensembl:ENSG00000229363(gene)|ensembl:ENSG00000231044(gene)|ensembl:ENSG00000233801(gene)|ensembl:ENST00000375429(transcript)|ensembl:ENST00000383174(transcript)|ensembl:ENST00000383343(transcript)|ensembl:ENST00000429857(transcript)|ensembl:ENST00000448628(transcript)|ensembl:ENST00000457397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0032021"(NELF complex)|go:"GO:0005634"(nucleus)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033102|interpro:IPR034637|interpro:IPR035979|mint:P18615|rcsb pdb:1X5P|rcsb pdb:2BZ2|rcsb pdb:2JX2|rcsb pdb:5OOB|rcsb pdb:6GML|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|dip:DIP-32669N refseq:NP_056271.3|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-9603505|reactome:R-HSA-167290|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008283"(cell population proliferation)|go:"GO:0032021"(NELF complex)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0048863"(stem cell differentiation)|go:"GO:2000737"(negative regulation of stem cell differentiation)|interpro:IPR010405(Cofactor of BRCA1)|rcsb pdb:6GML|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|mint:Q8WX92|dip:DIP-32670N - - comment:"author score: 122" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:AaBoPxRk9kFoijQiehOZtEZ+/OI9606 rogid:riNpwaKKh9L9WBarWlYQrmWgrXY9606 rigid:JwXrBRAPjOtb6ozRzYuV9l84nME false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N7H5 uniprotkb:Q9HCC0 intact:EBI-2607770|uniprotkb:O75239|uniprotkb:Q9H166|uniprotkb:Q9NUU9|ensembl:ENSP00000221265|uniprotkb:M0QX35 intact:EBI-2211296|uniprotkb:A6NIY9|uniprotkb:Q96C27|uniprotkb:Q9Y4L7|ensembl:ENSP00000343657 psi-mi:paf1_human(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:PD2(gene name synonym)|uniprotkb:Pancreatic differentiation protein 2(gene name synonym) psi-mi:mccb_human(display_long)|uniprotkb:MCCC2(gene name)|psi-mi:MCCC2(display_short)|uniprotkb:MCCB(gene name synonym)|uniprotkb:"3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta"(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482127|imex:IM-26985-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061961.2|ensembl:ENSG00000006712(gene)|ensembl:ENST00000221265(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030054"(cell junction)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|mint:Q8N7H5|rcsb pdb:4M6T|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|refseq:NP_001243755.1|dip:DIP-48673N refseq:NP_071415.1|refseq:XP_005248624.1|ensembl:ENSG00000131844(gene)|ensembl:ENST00000340941(transcript)|go:"GO:0002169"(3-methylcrotonyl-CoA carboxylase complex, mitochondrial)|go:"GO:0004485"(methylcrotonoyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0015936"(coenzyme A metabolic process)|go:"GO:1905202"(methylcrotonoyl-CoA carboxylase complex)|interpro:IPR011762(Acetyl-coenzyme A carboxyltransferase, N-terminal)|interpro:IPR011763(Acetyl-coenzyme A carboxyltransferase, C-terminal)|interpro:IPR029045|interpro:IPR034733|mint:Q9HCC0|reactome:R-HSA-196780|reactome:R-HSA-3371599|reactome:R-HSA-70895 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5Bf9gSdxgaufI30DVL8QAyVLqNk9606 rogid:5NkqDKqdX1wHsbqXW7v5+/Gld109606 rigid:JfZBVozhexwR33K0zwRXy0YfvvU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N7H5 uniprotkb:P54709 intact:EBI-2607770|uniprotkb:O75239|uniprotkb:Q9H166|uniprotkb:Q9NUU9|ensembl:ENSP00000221265|uniprotkb:M0QX35 intact:EBI-1054481|uniprotkb:B7Z1N7|ensembl:ENSP00000286371 psi-mi:paf1_human(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:PD2(gene name synonym)|uniprotkb:Pancreatic differentiation protein 2(gene name synonym) psi-mi:at1b3_human(display_long)|uniprotkb:Sodium/potassium-dependent ATPase subunit beta-3(gene name synonym)|uniprotkb:ATP1B3(gene name)|psi-mi:ATP1B3(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482127|imex:IM-26985-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061961.2|ensembl:ENSG00000006712(gene)|ensembl:ENST00000221265(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030054"(cell junction)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|mint:Q8N7H5|rcsb pdb:4M6T|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|refseq:NP_001243755.1|dip:DIP-48673N refseq:NP_001670.1|ensembl:ENSG00000069849(gene)|ensembl:ENST00000286371(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005391"("P-type sodium:potassium-exchanging transporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005890"("sodium:potassium-exchanging ATPase complex")|go:"GO:0005901"(caveola)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0042470"(melanosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0051117"(ATPase binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086009"(membrane repolarization)|go:"GO:1901018"(positive regulation of potassium ion transmembrane transporter activity)|go:"GO:1903278"(positive regulation of sodium ion export across plasma membrane)|go:"GO:1903288"(positive regulation of potassium ion import across plasma membrane)|go:"GO:1990573"(potassium ion import across plasma membrane)|interpro:IPR000402(ATPase, P-type cation exchange, beta subunit)|interpro:IPR038702|mint:P54709|reactome:R-HSA-210991|reactome:R-HSA-5578775|reactome:R-HSA-936837|reactome:R-HSA-9679191|dip:DIP-50717N - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5Bf9gSdxgaufI30DVL8QAyVLqNk9606 rogid:M7gSVe1bjKF7LqCZh/raoHBvp7M9606 rigid:JfZBVozhexwR33K0zwRXy0YfvvU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N7H5 uniprotkb:P00387 intact:EBI-2607770|uniprotkb:O75239|uniprotkb:Q9H166|uniprotkb:Q9NUU9|ensembl:ENSP00000221265|uniprotkb:M0QX35 intact:EBI-1046040|uniprotkb:O75675|uniprotkb:Q8TDL8|uniprotkb:Q8WTS8|uniprotkb:Q9UEN4|uniprotkb:Q9UEN5|uniprotkb:Q9UL55|uniprotkb:Q9UL56|uniprotkb:B1AHF2|uniprotkb:B7Z7L3|ensembl:ENSP00000338461 psi-mi:paf1_human(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:PD2(gene name synonym)|uniprotkb:Pancreatic differentiation protein 2(gene name synonym) psi-mi:nb5r3_human(display_long)|uniprotkb:Diaphorase-1(gene name synonym)|uniprotkb:CYB5R3(gene name)|psi-mi:CYB5R3(display_short)|uniprotkb:DIA1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482127|imex:IM-26985-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061961.2|ensembl:ENSG00000006712(gene)|ensembl:ENST00000221265(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030054"(cell junction)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|mint:Q8N7H5|rcsb pdb:4M6T|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|refseq:NP_001243755.1|dip:DIP-48673N refseq:NP_001165132.1|refseq:NP_000389.1|refseq:NP_001123291.1|refseq:NP_015565.1|refseq:NP_001165131.1|ensembl:ENSG00000100243(gene)|ensembl:ENST00000352397(transcript)|go:"GO:0004128"("cytochrome-b5 reductase activity, acting on NAD(P)H")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006809"(nitric oxide biosynthetic process)|go:"GO:0008015"(blood circulation)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043531"(ADP binding)|go:"GO:0051287"(NAD binding)|go:"GO:0071949"(FAD binding)|go:"GO:1903958"(nitric-oxide synthase complex)|interpro:IPR001433("Oxidoreductase FAD/NAD(P)-binding")|interpro:IPR001709(Flavoprotein pyridine nucleotide cytochrome reductase)|interpro:IPR001834("NADH:cytochrome b5 reductase (CBR)")|interpro:IPR008333(Oxidoreductase FAD-binding region)|interpro:IPR017927|interpro:IPR017938|mint:P00387|rcsb pdb:1M91|rcsb pdb:1UMK|reactome:R-HSA-196836|reactome:R-HSA-211945|reactome:R-HSA-6798695|interpro:IPR039261|dip:DIP-50463N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5Bf9gSdxgaufI30DVL8QAyVLqNk9606 rogid:Q8JTO6AXZ8LE4FXZAzOw2p4b6HY9606 rigid:JfZBVozhexwR33K0zwRXy0YfvvU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N7H5 uniprotkb:P35232 intact:EBI-2607770|uniprotkb:O75239|uniprotkb:Q9H166|uniprotkb:Q9NUU9|ensembl:ENSP00000221265|uniprotkb:M0QX35 intact:EBI-354213|uniprotkb:Q4VBQ0|uniprotkb:B4DY47|ensembl:ENSP00000300408|ensembl:ENSP00000393320|ensembl:ENSP00000422182|ensembl:ENSP00000425035|ensembl:ENSP00000426433|ensembl:ENSP00000479488|ensembl:ENSP00000484113 psi-mi:paf1_human(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:PD2(gene name synonym)|uniprotkb:Pancreatic differentiation protein 2(gene name synonym) psi-mi:phb_human(display_long)|uniprotkb:PHB(gene name)|psi-mi:PHB(display_short)|uniprotkb:PHB1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482127|imex:IM-26985-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061961.2|ensembl:ENSG00000006712(gene)|ensembl:ENST00000221265(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030054"(cell junction)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|mint:Q8N7H5|rcsb pdb:4M6T|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|refseq:NP_001243755.1|dip:DIP-48673N refseq:NP_001268426.1|refseq:NP_002625.1|refseq:NP_001268425.1|refseq:NP_001268644.1|refseq:XP_016880252.1|dip:DIP-24248N|ensembl:ENSG00000167085(gene)|ensembl:ENST00000300408(transcript)|ensembl:ENST00000419140(transcript)|ensembl:ENST00000504124(transcript)|ensembl:ENST00000511832(transcript)|ensembl:ENST00000512041(transcript)|ensembl:ENST00000614445(transcript)|ensembl:ENST00000617874(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001850"(complement component C3a binding)|go:"GO:0001851"(complement component C3b binding)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0010944"(negative regulation of transcription by competitive promoter binding)|go:"GO:0016020"(membrane)|go:"GO:0016575"(histone deacetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031871"(proteinase activated receptor binding)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0035632"(mitochondrial prohibitin complex)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0042113"(B cell activation)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045745"(positive regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045917"(positive regulation of complement activation)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1990051"(activation of protein kinase C activity)|go:"GO:2000323"(negative regulation of glucocorticoid receptor signaling pathway)|interpro:IPR000163(Prohibitin)|interpro:IPR001107(Band 7 protein)|interpro:IPR036013|mint:P35232|rcsb pdb:1LU7|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802955|reactome:R-HSA-8949664|reactome:R-HSA-9649948 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5Bf9gSdxgaufI30DVL8QAyVLqNk9606 rogid:aIJj/q/3JKXuEVRELjKJb2SjCKQ9606 rigid:JfZBVozhexwR33K0zwRXy0YfvvU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N7H5 uniprotkb:P06899 intact:EBI-2607770|uniprotkb:O75239|uniprotkb:Q9H166|uniprotkb:Q9NUU9|ensembl:ENSP00000221265|uniprotkb:M0QX35 intact:EBI-6150252|uniprotkb:B2R4J4|uniprotkb:O60816|ensembl:ENSP00000342886|ensembl:ENSP00000476136 psi-mi:paf1_human(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:PD2(gene name synonym)|uniprotkb:Pancreatic differentiation protein 2(gene name synonym) psi-mi:h2b1j_human(display_long)|uniprotkb:H2BC11(gene name)|psi-mi:H2BC11(display_short)|uniprotkb:H2BFR(gene name synonym)|uniprotkb:HIST1H2BJ(gene name synonym)|uniprotkb:Histone H2B.1(gene name synonym)|uniprotkb:Histone H2B.r(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482127|imex:IM-26985-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061961.2|ensembl:ENSG00000006712(gene)|ensembl:ENST00000221265(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030054"(cell junction)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|mint:Q8N7H5|rcsb pdb:4M6T|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|refseq:NP_001243755.1|dip:DIP-48673N refseq:NP_066402.2|dip:DIP-421N|ensembl:ENSG00000124635(gene)|ensembl:ENST00000339812(transcript)|ensembl:ENST00000607124(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P06899|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WAA|rcsb pdb:3WTP|rcsb pdb:4CAY|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5FUG|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5VEY|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6JXD|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6YOV|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7K5X|rcsb pdb:3WA9|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5Bf9gSdxgaufI30DVL8QAyVLqNk9606 rogid:74GQlSjGG1Ez6Uog74VXPLryKBc9606 rigid:JfZBVozhexwR33K0zwRXy0YfvvU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N7H5 uniprotkb:Q13011 intact:EBI-2607770|uniprotkb:O75239|uniprotkb:Q9H166|uniprotkb:Q9NUU9|ensembl:ENSP00000221265|uniprotkb:M0QX35 intact:EBI-711968|ensembl:ENSP00000221418|ensembl:ENSP00000489530|uniprotkb:Q8WVX0|uniprotkb:Q96EZ9|uniprotkb:A8K745 psi-mi:paf1_human(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:PD2(gene name synonym)|uniprotkb:Pancreatic differentiation protein 2(gene name synonym) psi-mi:ech1_human(display_long)|uniprotkb:ECH1(gene name)|psi-mi:ECH1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482127|imex:IM-26985-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061961.2|ensembl:ENSG00000006712(gene)|ensembl:ENST00000221265(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030054"(cell junction)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|mint:Q8N7H5|rcsb pdb:4M6T|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|refseq:NP_001243755.1|dip:DIP-48673N ensembl:ENSG00000104823(gene)|ensembl:ENSG00000282853(gene)|ensembl:ENST00000221418(transcript)|ensembl:ENST00000634245(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0016020"(membrane)|go:"GO:0051750"("delta(3,5)-delta(2,4)-dienoyl-CoA isomerase activity")|go:"GO:0070062"(extracellular exosome)|interpro:IPR001753(Crotonase, core)|interpro:IPR014748(Crontonase, C-terminal)|interpro:IPR018376|interpro:IPR029045|mint:Q13011|rcsb pdb:2VRE|reactome:R-HSA-9033241|refseq:NP_001389.2 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5Bf9gSdxgaufI30DVL8QAyVLqNk9606 rogid:gh0bwdUu9tkSTHWuySCaTXIQGzI9606 rigid:JfZBVozhexwR33K0zwRXy0YfvvU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N7H5 uniprotkb:O00264 intact:EBI-2607770|uniprotkb:O75239|uniprotkb:Q9H166|uniprotkb:Q9NUU9|ensembl:ENSP00000221265|uniprotkb:M0QX35 intact:EBI-1045534|uniprotkb:Q9UGJ9|ensembl:ENSP00000217971|uniprotkb:B7Z1L3 psi-mi:paf1_human(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:PD2(gene name synonym)|uniprotkb:Pancreatic differentiation protein 2(gene name synonym) psi-mi:pgrc1_human(display_long)|uniprotkb:Dap1(gene name synonym)|uniprotkb:IZA(gene name synonym)|uniprotkb:PGRMC1(gene name)|psi-mi:PGRMC1(display_short)|uniprotkb:HPR6.6(gene name synonym)|uniprotkb:PGRMC(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482127|imex:IM-26985-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061961.2|ensembl:ENSG00000006712(gene)|ensembl:ENST00000221265(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030054"(cell junction)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|mint:Q8N7H5|rcsb pdb:4M6T|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|refseq:NP_001243755.1|dip:DIP-48673N refseq:NP_001269550.1|ensembl:ENST00000217971(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005496"(steroid binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0020037"(heme binding)|go:"GO:0030868"(smooth endoplasmic reticulum membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|interpro:IPR001199(Cytochrome b5)|interpro:IPR036400|mint:O00264|rcsb pdb:4X8Y|reactome:R-HSA-6798695|ensembl:ENSG00000101856(gene)|refseq:NP_006658.1 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5Bf9gSdxgaufI30DVL8QAyVLqNk9606 rogid:fjKpwgj9042mPhLsvS/wu1wBEi89606 rigid:JfZBVozhexwR33K0zwRXy0YfvvU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N7H5 uniprotkb:Q96RQ3 intact:EBI-2607770|uniprotkb:O75239|uniprotkb:Q9H166|uniprotkb:Q9NUU9|ensembl:ENSP00000221265|uniprotkb:M0QX35 intact:EBI-2211703|uniprotkb:Q59ES4|uniprotkb:Q9H959|uniprotkb:Q9NS97|ensembl:ENSP00000265594 psi-mi:paf1_human(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:PD2(gene name synonym)|uniprotkb:Pancreatic differentiation protein 2(gene name synonym) psi-mi:mcca_human(display_long)|uniprotkb:MCCC1(gene name)|psi-mi:MCCC1(display_short)|uniprotkb:MCCA(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase 1(gene name synonym)|uniprotkb:"3-methylcrotonyl-CoA:carbon dioxide ligase subunit alpha"(gene name synonym)|uniprotkb:3-methylcrotonyl-CoA carboxylase biotin-containing subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482127|imex:IM-26985-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061961.2|ensembl:ENSG00000006712(gene)|ensembl:ENST00000221265(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030054"(cell junction)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|mint:Q8N7H5|rcsb pdb:4M6T|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|refseq:NP_001243755.1|dip:DIP-48673N refseq:NP_064551.3|refseq:NP_001280202.1|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR016185(PreATP-grasp-like fold)|mint:Q96RQ3|rcsb pdb:2EJM|reactome:R-HSA-196780|reactome:R-HSA-3371599|reactome:R-HSA-70895|ensembl:ENSG00000078070(gene)|ensembl:ENST00000265594(transcript)|go:"GO:0002169"(3-methylcrotonyl-CoA carboxylase complex, mitochondrial)|go:"GO:0004075"(biotin carboxylase activity)|go:"GO:0004485"(methylcrotonoyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0006768"(biotin metabolic process)|go:"GO:0009374"(biotin binding)|go:"GO:0016421"(CoA carboxylase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:1905202"(methylcrotonoyl-CoA carboxylase complex)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001882(Biotin-binding site)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding) - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5Bf9gSdxgaufI30DVL8QAyVLqNk9606 rogid:obze7v7i2yTIIcJjd7laIriNFg89606 rigid:JfZBVozhexwR33K0zwRXy0YfvvU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N7H5 uniprotkb:P21796 intact:EBI-2607770|uniprotkb:O75239|uniprotkb:Q9H166|uniprotkb:Q9NUU9|ensembl:ENSP00000221265|uniprotkb:M0QX35 intact:EBI-354158|uniprotkb:Q5FVE7|uniprotkb:Q9UIQ5|uniprotkb:Q9UPL0|uniprotkb:B3KVK4|uniprotkb:D3DQ93|ensembl:ENSP00000265333|ensembl:ENSP00000378484|ensembl:ENSP00000378487 psi-mi:paf1_human(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:PD2(gene name synonym)|uniprotkb:Pancreatic differentiation protein 2(gene name synonym) psi-mi:vdac1_human(display_long)|uniprotkb:VDAC1(gene name)|psi-mi:VDAC1(display_short)|uniprotkb:VDAC(gene name synonym)|uniprotkb:Outer mitochondrial membrane protein porin 1(gene name synonym)|uniprotkb:Plasmalemmal porin(gene name synonym)|uniprotkb:Porin 31HL(gene name synonym)|uniprotkb:Porin 31HM(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482127|imex:IM-26985-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061961.2|ensembl:ENSG00000006712(gene)|ensembl:ENST00000221265(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030054"(cell junction)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|mint:Q8N7H5|rcsb pdb:4M6T|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|refseq:NP_001243755.1|dip:DIP-48673N refseq:NP_003365.1|refseq:XP_005272132.1|refseq:XP_016865310.1|refseq:XP_016865311.1|refseq:XP_016865312.1|dip:DIP-32862N|ensembl:ENSG00000213585(gene)|ensembl:ENST00000265333(transcript)|ensembl:ENST00000395044(transcript)|ensembl:ENST00000395047(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005757"(mitochondrial permeability transition pore complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006820"(anion transport)|go:"GO:0006851"(mitochondrial calcium ion transmembrane transport)|go:"GO:0006915"(apoptotic process)|go:"GO:0007270"(neuron-neuron synaptic transmission)|go:"GO:0007612"(learning)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008308"(voltage-gated anion channel activity)|go:"GO:0015288"(porin activity)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046930"(pore complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097001"(ceramide binding)|go:"GO:0110099"(negative regulation of calcium import into the mitochondrion)|go:"GO:1901526"(positive regulation of mitophagy)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|interpro:IPR001925(Porin, eukaryotic type)|interpro:IPR023614|interpro:IPR027246|interpro:IPR030270|mint:P21796|rcsb pdb:2JK4|rcsb pdb:2K4T|rcsb pdb:5JDP|rcsb pdb:5XDN|rcsb pdb:5XDO|rcsb pdb:6G6U|rcsb pdb:6G73|rcsb pdb:6TIQ|rcsb pdb:6TIR|reactome:R-HSA-1268020|reactome:R-HSA-5205685|reactome:R-HSA-5689880|reactome:R-HSA-70268|reactome:R-HSA-8949215 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5Bf9gSdxgaufI30DVL8QAyVLqNk9606 rogid:8Fqe6Ga3NmwwuICa4L45ga2i1nk9606 rigid:JfZBVozhexwR33K0zwRXy0YfvvU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N7H5 uniprotkb:Q9H9S4 intact:EBI-2607770|uniprotkb:O75239|uniprotkb:Q9H166|uniprotkb:Q9NUU9|ensembl:ENSP00000221265|uniprotkb:M0QX35 intact:EBI-1047244|uniprotkb:Q5TAW6|uniprotkb:Q6WG71|uniprotkb:Q96FG1|uniprotkb:Q9BZ33|ensembl:ENSP00000261669|ensembl:ENSP00000348113|ensembl:ENSP00000386328|ensembl:ENSP00000386375|ensembl:ENSP00000479669 psi-mi:paf1_human(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:PD2(gene name synonym)|uniprotkb:Pancreatic differentiation protein 2(gene name synonym) psi-mi:cb39l_human(display_long)|uniprotkb:Mo25-like protein(gene name synonym)|uniprotkb:Antigen MLAA-34(gene name synonym)|uniprotkb:CAB39L(gene name)|psi-mi:CAB39L(display_short)|uniprotkb:MO25beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482127|imex:IM-26985-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061961.2|ensembl:ENSG00000006712(gene)|ensembl:ENST00000221265(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030054"(cell junction)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|mint:Q8N7H5|rcsb pdb:4M6T|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|refseq:NP_001243755.1|dip:DIP-48673N ensembl:ENSG00000102547(gene)|ensembl:ENST00000347776(transcript)|ensembl:ENST00000355854(transcript)|ensembl:ENST00000409308(transcript)|ensembl:ENST00000410043(transcript)|ensembl:ENST00000610540(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013878(Mo25-like)|interpro:IPR016024(Armadillo-type fold)|mint:Q9H9S4|rcsb pdb:3ZHP|reactome:R-HSA-380972|refseq:NP_001073138.1|refseq:NP_112187.2|refseq:XP_011533556.1|refseq:XP_011533557.1|refseq:XP_011533558.1|refseq:NP_001274266.1|refseq:NP_001274267.1|refseq:NP_001274268.1|refseq:XP_016876274.1|refseq:XP_016876275.1|refseq:XP_016876276.1|refseq:XP_016876277.1 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5Bf9gSdxgaufI30DVL8QAyVLqNk9606 rogid:YmPStpkw+Uhuh5A+NHcCAVGaUtQ9606 rigid:JfZBVozhexwR33K0zwRXy0YfvvU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N7H5 uniprotkb:P14406 intact:EBI-2607770|uniprotkb:O75239|uniprotkb:Q9H166|uniprotkb:Q9NUU9|ensembl:ENSP00000221265|uniprotkb:M0QX35 intact:EBI-2606666|uniprotkb:Q5TF59|uniprotkb:Q6FGI2|uniprotkb:Q3MIH5|uniprotkb:B2R5E1|ensembl:ENSP00000506727 psi-mi:paf1_human(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:PD2(gene name synonym)|uniprotkb:Pancreatic differentiation protein 2(gene name synonym) psi-mi:cx7a2_human(display_long)|uniprotkb:COX7AL(gene name synonym)|uniprotkb:Cytochrome c oxidase subunit VIIa-liver/heart(gene name synonym)|uniprotkb:COX7A2(gene name)|psi-mi:COX7A2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482127|imex:IM-26985-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061961.2|ensembl:ENSG00000006712(gene)|ensembl:ENST00000221265(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030054"(cell junction)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|mint:Q8N7H5|rcsb pdb:4M6T|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|refseq:NP_001243755.1|dip:DIP-48673N refseq:NP_001856.2|ensembl:ENSG00000112695(gene)|ensembl:ENST00000684430(transcript)|go:"GO:0002082"(regulation of oxidative phosphorylation)|go:"GO:0005746"(mitochondrial respirasome)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0097250"(mitochondrial respirasome assembly)|interpro:IPR003177(Cytochrome c oxidase, subunit VIIa)|interpro:IPR036539|interpro:IPR039297|mint:P14406|rcsb pdb:5Z62 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5Bf9gSdxgaufI30DVL8QAyVLqNk9606 rogid:krjTK658npBV4G6gH28GJhVqBkY9606 rigid:JfZBVozhexwR33K0zwRXy0YfvvU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N7H5 uniprotkb:P05166 intact:EBI-2607770|uniprotkb:O75239|uniprotkb:Q9H166|uniprotkb:Q9NUU9|ensembl:ENSP00000221265|uniprotkb:M0QX35 intact:EBI-1371908|uniprotkb:Q16813|uniprotkb:Q96CX0|uniprotkb:B7Z2Z4|ensembl:ENSP00000251654 psi-mi:paf1_human(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:PD2(gene name synonym)|uniprotkb:Pancreatic differentiation protein 2(gene name synonym) psi-mi:pccb_human(display_long)|uniprotkb:PCCB(gene name)|psi-mi:PCCB(display_short)|uniprotkb:"Propanoyl-CoA:carbon dioxide ligase subunit beta"(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482127|imex:IM-26985-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061961.2|ensembl:ENSG00000006712(gene)|ensembl:ENST00000221265(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030054"(cell junction)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|mint:Q8N7H5|rcsb pdb:4M6T|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|refseq:NP_001243755.1|dip:DIP-48673N refseq:NP_000523.2|refseq:NP_001171485.1|dip:DIP-38244N|mint:P05166|reactome:R-HSA-196780|reactome:R-HSA-3371599|reactome:R-HSA-71032|interpro:IPR034733|ensembl:ENSG00000114054(gene)|ensembl:ENST00000251654(transcript)|go:"GO:0004658"(propionyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0019626"(short-chain fatty acid catabolic process)|interpro:IPR011762(Acetyl-coenzyme A carboxyltransferase, N-terminal)|interpro:IPR011763(Acetyl-coenzyme A carboxyltransferase, C-terminal)|interpro:IPR029045 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5Bf9gSdxgaufI30DVL8QAyVLqNk9606 rogid:QyhO7MHvNRxNMg7ohwi1xS+VxQE9606 rigid:JfZBVozhexwR33K0zwRXy0YfvvU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N7H5 uniprotkb:P18859 intact:EBI-2607770|uniprotkb:O75239|uniprotkb:Q9H166|uniprotkb:Q9NUU9|ensembl:ENSP00000221265|uniprotkb:M0QX35 intact:EBI-2606700|ensembl:ENSP00000284971|ensembl:ENSP00000382959|ensembl:ENSP00000382962|ensembl:ENSP00000382965|ensembl:ENSP00000382966|uniprotkb:J3KQ83 psi-mi:paf1_human(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:PD2(gene name synonym)|uniprotkb:Pancreatic differentiation protein 2(gene name synonym) psi-mi:atp5j_human(display_long)|uniprotkb:ATP5PF(gene name)|psi-mi:ATP5PF(display_short)|uniprotkb:ATP synthase peripheral stalk subunit F6(gene name synonym)|uniprotkb:ATP5A(gene name synonym)|uniprotkb:ATP5J(gene name synonym)|uniprotkb:ATPM(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482127|imex:IM-26985-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061961.2|ensembl:ENSG00000006712(gene)|ensembl:ENST00000221265(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030054"(cell junction)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|mint:Q8N7H5|rcsb pdb:4M6T|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|refseq:NP_001243755.1|dip:DIP-48673N refseq:NP_001003696.1|refseq:NP_001003697.1|refseq:NP_001003701.1|refseq:NP_001003703.1|refseq:NP_001676.2|go:"GO:0005615"(extracellular space)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0009986"(cell surface)|go:"GO:0010460"(positive regulation of heart rate)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0021762"(substantia nigra development)|go:"GO:0032307"(negative regulation of prostaglandin secretion)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045777"(positive regulation of blood pressure)|go:"GO:1900139"(negative regulation of arachidonic acid secretion)|interpro:IPR008387(ATPase, F0 complex, subunit F6, mitochondrial)|interpro:IPR036204|mint:P18859|reactome:R-HSA-163210|reactome:R-HSA-8949613|ensembl:ENSG00000154723(gene)|ensembl:ENST00000284971(transcript)|ensembl:ENST00000400087(transcript)|ensembl:ENST00000400090(transcript)|ensembl:ENST00000400093(transcript)|ensembl:ENST00000400094(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|refseq:NP_001307195.1|refseq:NP_001307196.1 - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5Bf9gSdxgaufI30DVL8QAyVLqNk9606 rogid:0swdCmCT2TBep9+xToVV0Ntl2ZA9606 rigid:JfZBVozhexwR33K0zwRXy0YfvvU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N7H5 uniprotkb:P20674 intact:EBI-2607770|uniprotkb:O75239|uniprotkb:Q9H166|uniprotkb:Q9NUU9|ensembl:ENSP00000221265|uniprotkb:M0QX35 intact:EBI-715032|uniprotkb:P30045|intact:EBI-1043629|uniprotkb:Q8TB65|ensembl:ENSP00000317780|ensembl:ENSP00000456386 psi-mi:paf1_human(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:PD2(gene name synonym)|uniprotkb:Pancreatic differentiation protein 2(gene name synonym) psi-mi:cox5a_human(display_long)|uniprotkb:Cytochrome c oxidase polypeptide Va(gene name synonym)|uniprotkb:COX5A(gene name)|psi-mi:COX5A(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482127|imex:IM-26985-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061961.2|ensembl:ENSG00000006712(gene)|ensembl:ENST00000221265(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030054"(cell junction)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|mint:Q8N7H5|rcsb pdb:4M6T|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|refseq:NP_001243755.1|dip:DIP-48673N refseq:NP_004246.2|interpro:IPR003204(Cytochrome c oxidase, subunit Va)|interpro:IPR036545|mint:P20674|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564|go:"GO:0046872"(metal ion binding)|ensembl:ENSG00000178741(gene)|ensembl:ENST00000322347(transcript)|ensembl:ENST00000564811(transcript)|go:"GO:0004129"(cytochrome-c oxidase activity)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0009055"(electron transfer activity) - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5Bf9gSdxgaufI30DVL8QAyVLqNk9606 rogid:dWvZKYawyJQwN29Mhkm44DXXqhg9606 rigid:JfZBVozhexwR33K0zwRXy0YfvvU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N7H5 uniprotkb:P11498 intact:EBI-2607770|uniprotkb:O75239|uniprotkb:Q9H166|uniprotkb:Q9NUU9|ensembl:ENSP00000221265|uniprotkb:M0QX35 intact:EBI-2211322|uniprotkb:Q16705|uniprotkb:B4DN00|ensembl:ENSP00000377527|ensembl:ENSP00000377530|ensembl:ENSP00000377532|ensembl:ENSP00000435905|ensembl:ENSP00000498302|ensembl:ENSP00000498406|ensembl:ENSP00000498994 psi-mi:paf1_human(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:PD2(gene name synonym)|uniprotkb:Pancreatic differentiation protein 2(gene name synonym) psi-mi:pyc_human(display_long)|uniprotkb:PC(gene name)|psi-mi:PC(display_short)|uniprotkb:Pyruvic carboxylase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482127|imex:IM-26985-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061961.2|ensembl:ENSG00000006712(gene)|ensembl:ENST00000221265(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030054"(cell junction)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|mint:Q8N7H5|rcsb pdb:4M6T|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|refseq:NP_001243755.1|dip:DIP-48673N refseq:XP_011543388.1|refseq:XP_016873357.1|refseq:XP_016873358.1|refseq:XP_016873359.1|refseq:XP_016873360.1|refseq:XP_016873361.1|refseq:NP_000911.2|refseq:NP_001035806.1|refseq:NP_071504.2|refseq:XP_005274088.1|refseq:XP_005274089.1|refseq:XP_006718641.1|dip:DIP-46372N|ensembl:ENSG00000173599(gene)|ensembl:ENST00000393955(transcript)|ensembl:ENST00000393958(transcript)|ensembl:ENST00000393960(transcript)|ensembl:ENST00000529047(transcript)|ensembl:ENST00000651036(transcript)|ensembl:ENST00000651854(transcript)|ensembl:ENST00000652125(transcript)|go:"GO:0004736"(pyruvate carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006090"(pyruvate metabolic process)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0009374"(biotin binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0042802"(identical protein binding)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0046872"(metal ion binding)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR000891(Pyruvate carboxyltransferase)|interpro:IPR001882(Biotin-binding site)|interpro:IPR003379(Conserved carboxylase region)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR005930(Pyruvate carboxylase)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR016185(PreATP-grasp-like fold)|mint:P11498|rcsb pdb:3BG3|rcsb pdb:3BG9|reactome:R-HSA-196780|reactome:R-HSA-3371599|reactome:R-HSA-70263 - - comment:"author score: 27" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5Bf9gSdxgaufI30DVL8QAyVLqNk9606 rogid:0xXv1wxe0AC1EO7wxSDVhBpHCUU9606 rigid:JfZBVozhexwR33K0zwRXy0YfvvU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N7H5 uniprotkb:P05165 intact:EBI-2607770|uniprotkb:O75239|uniprotkb:Q9H166|uniprotkb:Q9NUU9|ensembl:ENSP00000221265|uniprotkb:M0QX35 intact:EBI-2211679|uniprotkb:B4DPF9|uniprotkb:C9JPQ8|uniprotkb:B4DKY8|uniprotkb:Q15979|intact:EBI-2803938|uniprotkb:Q8WXQ7|ensembl:ENSP00000365462 psi-mi:paf1_human(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:PD2(gene name synonym)|uniprotkb:Pancreatic differentiation protein 2(gene name synonym) psi-mi:pcca_human(display_long)|uniprotkb:PCCA(gene name)|psi-mi:PCCA(display_short)|uniprotkb:"Propanoyl-CoA:carbon dioxide ligase subunit alpha"(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482127|imex:IM-26985-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061961.2|ensembl:ENSG00000006712(gene)|ensembl:ENST00000221265(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030054"(cell junction)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|mint:Q8N7H5|rcsb pdb:4M6T|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|refseq:NP_001243755.1|dip:DIP-48673N refseq:NP_000273.2|refseq:NP_001121164.1|refseq:NP_001171475.1|dip:DIP-57493N|ensembl:ENSG00000175198(gene)|ensembl:ENST00000376285(transcript)|go:"GO:0004658"(propionyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0009374"(biotin binding)|go:"GO:0016421"(CoA carboxylase activity)|go:"GO:0019626"(short-chain fatty acid catabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001882(Biotin-binding site)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR041265|mint:P05165|rcsb pdb:2CQY|rcsb pdb:2JKU|reactome:R-HSA-196780|reactome:R-HSA-3371599|reactome:R-HSA-71032 - - comment:"author score: 31" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5Bf9gSdxgaufI30DVL8QAyVLqNk9606 rogid:IR3jXR6XjVwD8WRNlN4N5+AOk049606 rigid:JfZBVozhexwR33K0zwRXy0YfvvU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N7H5 uniprotkb:Q13085 intact:EBI-2607770|uniprotkb:O75239|uniprotkb:Q9H166|uniprotkb:Q9NUU9|ensembl:ENSP00000221265|uniprotkb:M0QX35 intact:EBI-717681|intact:EBI-3962262|uniprotkb:B2ZZ90|uniprotkb:Q6KEV6|uniprotkb:Q6XDA8|uniprotkb:Q7Z2G8|uniprotkb:Q7Z561|uniprotkb:Q7Z563|uniprotkb:Q7Z564|uniprotkb:Q86WB2|uniprotkb:Q86WB3|uniprotkb:B2RP68|ensembl:ENSP00000478547|ensembl:ENSP00000483674 psi-mi:paf1_human(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:PD2(gene name synonym)|uniprotkb:Pancreatic differentiation protein 2(gene name synonym) psi-mi:acaca_human(display_long)|uniprotkb:ACACA(gene name)|psi-mi:ACACA(display_short)|uniprotkb:ACAC(gene name synonym)|uniprotkb:ACC1(gene name synonym)|uniprotkb:ACCA(gene name synonym)|uniprotkb:Acetyl-Coenzyme A carboxylase alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482127|imex:IM-26985-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061961.2|ensembl:ENSG00000006712(gene)|ensembl:ENST00000221265(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030054"(cell junction)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|mint:Q8N7H5|rcsb pdb:4M6T|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|refseq:NP_001243755.1|dip:DIP-48673N refseq:NP_942131.1|refseq:NP_942133.1|refseq:NP_942134.1|refseq:NP_942135.1|refseq:NP_942136.1|refseq:XP_016880044.1|refseq:XP_011523005.1|ensembl:ENSG00000275176(gene)|ensembl:ENSG00000278540(gene)|ensembl:ENST00000613687(transcript)|ensembl:ENST00000614428(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003989"(acetyl-CoA carboxylase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019538"(protein metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046949"(fatty-acyl-CoA biosynthetic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:2001295"(malonyl-CoA biosynthetic process)|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001882(Biotin-binding site)|interpro:IPR005479(Carbamoyl phosphate synthetase, large subunit, ATP-binding)|interpro:IPR005481(Carbamoyl phosphate synthase, large subunit, N-terminal)|interpro:IPR005482(Biotin carboxylase, C-terminal)|interpro:IPR011053(Single hybrid motif)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|interpro:IPR011762(Acetyl-coenzyme A carboxyltransferase, N-terminal)|interpro:IPR011763(Acetyl-coenzyme A carboxyltransferase, C-terminal)|interpro:IPR011764(Biotin carboxylation region)|interpro:IPR013537(Acetyl-CoA carboxylase, central region)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|interpro:IPR016185(PreATP-grasp-like fold)|interpro:IPR029045|interpro:IPR034733|mint:Q13085|rcsb pdb:2YL2|rcsb pdb:3COJ|rcsb pdb:4ASI|rcsb pdb:6G2D|rcsb pdb:6G2H|rcsb pdb:6G2I|reactome:R-HSA-163765|reactome:R-HSA-196780|reactome:R-HSA-200425|reactome:R-HSA-2426168|reactome:R-HSA-3371599|reactome:R-HSA-75105|dip:DIP-36122N - - comment:"author score: 43" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5Bf9gSdxgaufI30DVL8QAyVLqNk9606 rogid:P9d0QlkoP1zrBdF1WOrK68ueGng9606 rigid:JfZBVozhexwR33K0zwRXy0YfvvU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N7H5 uniprotkb:Q8WVC0 intact:EBI-2607770|uniprotkb:O75239|uniprotkb:Q9H166|uniprotkb:Q9NUU9|ensembl:ENSP00000221265|uniprotkb:M0QX35 intact:EBI-932432|uniprotkb:Q96N99|ensembl:ENSP00000299601 psi-mi:paf1_human(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:PD2(gene name synonym)|uniprotkb:Pancreatic differentiation protein 2(gene name synonym) psi-mi:leo1_human(display_long)|uniprotkb:LEO1(gene name)|psi-mi:LEO1(display_short)|uniprotkb:RDL(gene name synonym)|uniprotkb:Replicative senescence down-regulated leo1-like protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482127|imex:IM-26985-45 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061961.2|ensembl:ENSG00000006712(gene)|ensembl:ENST00000221265(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030054"(cell junction)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|mint:Q8N7H5|rcsb pdb:4M6T|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|refseq:NP_001243755.1|dip:DIP-48673N refseq:NP_001273359.1|refseq:NP_620147.1|dip:DIP-37885N|ensembl:ENSG00000166477(gene)|ensembl:ENST00000299601(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|interpro:IPR007149(Leo1-like protein)|mint:Q8WVC0|rcsb pdb:4M6T|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-201722|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654 - - comment:"author score: 86" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5Bf9gSdxgaufI30DVL8QAyVLqNk9606 rogid:o0aaW4nxzWuPZ8/pMZpa9Qz9oEA9606 rigid:JfZBVozhexwR33K0zwRXy0YfvvU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N5Y8 uniprotkb:Q9P035 intact:EBI-10266912|uniprotkb:Q9NX03|uniprotkb:Q6PK64|uniprotkb:A0A024R5Y7|ensembl:ENSP00000496935 intact:EBI-359013|intact:EBI-1049123|uniprotkb:A0PJA1|uniprotkb:Q280Z3|uniprotkb:Q6PD63|uniprotkb:Q8IUI5|uniprotkb:Q8NC86|uniprotkb:Q8NCB1|uniprotkb:Q96T12|uniprotkb:Q9NQA7|uniprotkb:B4DRF4|intact:EBI-28973764|ensembl:ENSP00000261875 psi-mi:par16_human(display_long)|uniprotkb:PARP16(gene name)|psi-mi:PARP16(display_short)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 15(gene name synonym)|uniprotkb:ARTD15(gene name synonym)|uniprotkb:C15orf30(gene name synonym)|uniprotkb:Poly [ADP-ribose] polymerase 16(gene name synonym) psi-mi:hacd3_human(display_long)|uniprotkb:Butyrate-induced protein 1(gene name synonym)|uniprotkb:PTPLAD1(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase-like A domain-containing protein 1(gene name synonym)|uniprotkb:HACD3(gene name)|psi-mi:HACD3(display_short)|uniprotkb:3-hydroxyacyl-CoA dehydratase 3(gene name synonym)|uniprotkb:BIND1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482187|imex:IM-26985-117 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001303872.1|refseq:NP_001303873.1|refseq:NP_060321.3|ensembl:ENSG00000138617(gene)|ensembl:ENST00000649807(transcript)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0019900"(kinase binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034356"(NAD biosynthesis via nicotinamide riboside salvage pathway)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0140289"(protein mono-ADP-ribosylation)|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR041400|mint:Q8N5Y8|rcsb pdb:4F0D|rcsb pdb:6HXR|rcsb pdb:6HXS|rcsb pdb:6W65|reactome:R-HSA-197264|reactome:R-HSA-9683610|reactome:R-HSA-9694631 ensembl:ENSP00000261875|ensembl:ENST00000442729|ensembl:ENSP00000392491|refseq:NP_057479.2|ensembl:ENSG00000074696(gene)|ensembl:ENST00000261875(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005925"(focal adhesion)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0018812"(3-hydroxyacyl-CoA dehydratase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030497"(fatty acid elongation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042761"(very long-chain fatty acid biosynthetic process)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0046726"(positive regulation by virus of viral protein levels in host cell)|go:"GO:0102158"(very-long-chain 3-hydroxyacyl-CoA dehydratase activity)|go:"GO:0102343"(3-hydroxy-arachidoyl-CoA dehydratase activity)|go:"GO:0102344"(3-hydroxy-behenoyl-CoA dehydratase activity)|go:"GO:0102345"(3-hydroxy-lignoceroyl-CoA dehydratase activity)|interpro:IPR007052(CS domain)|interpro:IPR007482(Protein-tyrosine phosphatase-like, PTPLA)|interpro:IPR008978(HSP20-like chaperone)|mint:Q9P035|reactome:R-HSA-75876 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yKfTQw98LCuMIwB4Sm99uB24QUU9606 rogid:U31K6H8I2f5j7FRhfHiY0cG4smA9606 rigid:fr6O3PoYpW1jB+8U8AKqMqOjga8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N5Y8 uniprotkb:O00483 intact:EBI-10266912|uniprotkb:Q9NX03|uniprotkb:Q6PK64|uniprotkb:A0A024R5Y7|ensembl:ENSP00000496935 intact:EBI-1049381|uniprotkb:Q6FHN5|uniprotkb:A4D109|ensembl:ENSP00000339720 psi-mi:par16_human(display_long)|uniprotkb:PARP16(gene name)|psi-mi:PARP16(display_short)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 15(gene name synonym)|uniprotkb:ARTD15(gene name synonym)|uniprotkb:C15orf30(gene name synonym)|uniprotkb:Poly [ADP-ribose] polymerase 16(gene name synonym) psi-mi:ndua4_human(display_long)|uniprotkb:NADH-ubiquinone oxidoreductase MLRQ subunit(gene name synonym)|uniprotkb:Complex I-MLRQ(gene name synonym)|uniprotkb:NDUFA4(gene name)|psi-mi:NDUFA4(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482187|imex:IM-26985-117 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001303872.1|refseq:NP_001303873.1|refseq:NP_060321.3|ensembl:ENSG00000138617(gene)|ensembl:ENST00000649807(transcript)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0019900"(kinase binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034356"(NAD biosynthesis via nicotinamide riboside salvage pathway)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0140289"(protein mono-ADP-ribosylation)|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR041400|mint:Q8N5Y8|rcsb pdb:4F0D|rcsb pdb:6HXR|rcsb pdb:6HXS|rcsb pdb:6W65|reactome:R-HSA-197264|reactome:R-HSA-9683610|reactome:R-HSA-9694631 refseq:NP_002480.1|ensembl:ENSG00000189043(gene)|ensembl:ENST00000339600(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005747"(mitochondrial respiratory chain complex I)|go:"GO:0005751"(mitochondrial respiratory chain complex IV)|go:"GO:0006120"(mitochondrial electron transport, NADH to ubiquinone)|go:"GO:0008137"("NADH dehydrogenase (ubiquinone) activity")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1904960"(positive regulation of cytochrome-c oxidase activity)|interpro:IPR010530(B12D)|mint:O00483|rcsb pdb:5Z62|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9707564 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yKfTQw98LCuMIwB4Sm99uB24QUU9606 rogid:TnrYlkH8abl42/yGsvfc8Bh6Mu09606 rigid:fr6O3PoYpW1jB+8U8AKqMqOjga8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N5Y8 uniprotkb:P50402 intact:EBI-10266912|uniprotkb:Q9NX03|uniprotkb:Q6PK64|uniprotkb:A0A024R5Y7|ensembl:ENSP00000496935 intact:EBI-489887|uniprotkb:Q6FI02|ensembl:ENSP00000358857|ensembl:ENSP00000507533 psi-mi:par16_human(display_long)|uniprotkb:PARP16(gene name)|psi-mi:PARP16(display_short)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 15(gene name synonym)|uniprotkb:ARTD15(gene name synonym)|uniprotkb:C15orf30(gene name synonym)|uniprotkb:Poly [ADP-ribose] polymerase 16(gene name synonym) psi-mi:emd_human(display_long)|uniprotkb:EDMD(gene name synonym)|uniprotkb:STA(gene name synonym)|uniprotkb:EMD(gene name)|psi-mi:EMD(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482187|imex:IM-26985-117 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001303872.1|refseq:NP_001303873.1|refseq:NP_060321.3|ensembl:ENSG00000138617(gene)|ensembl:ENST00000649807(transcript)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0019900"(kinase binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034356"(NAD biosynthesis via nicotinamide riboside salvage pathway)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0140289"(protein mono-ADP-ribosylation)|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR041400|mint:Q8N5Y8|rcsb pdb:4F0D|rcsb pdb:6HXR|rcsb pdb:6HXS|rcsb pdb:6W65|reactome:R-HSA-197264|reactome:R-HSA-9683610|reactome:R-HSA-9694631 refseq:NP_000108.1|ensembl:ENSP00000358857|ensembl:ENSP00000507533|ensembl:ENSG00000102119(gene)|ensembl:ENST00000369842(transcript)|ensembl:ENST00000683627(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071763"(nuclear membrane organization)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR011015(LEM-like fold)|interpro:IPR034989|interpro:IPR035004|mint:P50402|rcsb pdb:1JEI|rcsb pdb:2ODC|rcsb pdb:2ODG|rcsb pdb:6GHD|rcsb pdb:6RPR|rcsb pdb:7NDY|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609523|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|dip:DIP-34638N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yKfTQw98LCuMIwB4Sm99uB24QUU9606 rogid:hqH2sFjAGwjIGtGX/rjVVFgaYsE9606 rigid:fr6O3PoYpW1jB+8U8AKqMqOjga8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N5Y8 uniprotkb:Q01650 intact:EBI-10266912|uniprotkb:Q9NX03|uniprotkb:Q6PK64|uniprotkb:A0A024R5Y7|ensembl:ENSP00000496935 intact:EBI-6138761|uniprotkb:Q8IV97|uniprotkb:Q9UBN8|uniprotkb:Q9UP15|uniprotkb:Q9UQC0|ensembl:ENSP00000261622 psi-mi:par16_human(display_long)|uniprotkb:PARP16(gene name)|psi-mi:PARP16(display_short)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 15(gene name synonym)|uniprotkb:ARTD15(gene name synonym)|uniprotkb:C15orf30(gene name synonym)|uniprotkb:Poly [ADP-ribose] polymerase 16(gene name synonym) psi-mi:lat1_human(display_long)|uniprotkb:SLC7A5(gene name)|psi-mi:SLC7A5(display_short)|uniprotkb:CD98LC(gene name synonym)|uniprotkb:LAT1(gene name synonym)|uniprotkb:MPE16(gene name synonym)|uniprotkb:4F2 light chain(gene name synonym)|uniprotkb:CD98 light chain(gene name synonym)|uniprotkb:Integral membrane protein E16(gene name synonym)|uniprotkb:L-type amino acid transporter 1(gene name synonym)|uniprotkb:Solute carrier family 7 member 5(gene name synonym)|uniprotkb:y+ system cationic amino acid transporter(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482187|imex:IM-26985-117 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001303872.1|refseq:NP_001303873.1|refseq:NP_060321.3|ensembl:ENSG00000138617(gene)|ensembl:ENST00000649807(transcript)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0019900"(kinase binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034356"(NAD biosynthesis via nicotinamide riboside salvage pathway)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0140289"(protein mono-ADP-ribosylation)|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR041400|mint:Q8N5Y8|rcsb pdb:4F0D|rcsb pdb:6HXR|rcsb pdb:6HXS|rcsb pdb:6W65|reactome:R-HSA-197264|reactome:R-HSA-9683610|reactome:R-HSA-9694631 refseq:NP_003477.4|ensembl:ENSG00000103257(gene)|ensembl:ENST00000261622(transcript)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015173"(aromatic amino acid transmembrane transporter activity)|go:"GO:0015175"(neutral amino acid transmembrane transporter activity)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015190"(L-leucine transmembrane transporter activity)|go:"GO:0015196"(L-tryptophan transmembrane transporter activity)|go:"GO:0015349"(thyroid hormone transmembrane transporter activity)|go:"GO:0015823"(phenylalanine transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032740"(positive regulation of interleukin-17 production)|go:"GO:0032753"(positive regulation of interleukin-4 production)|go:"GO:0042605"(peptide antigen binding)|go:"GO:0042908"(xenobiotic transport)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070327"(thyroid hormone transport)|go:"GO:0089718"(amino acid import across plasma membrane)|go:"GO:0098591"(external side of apical plasma membrane)|go:"GO:0098713"(leucine import across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1903801"(L-leucine import across plasma membrane)|go:"GO:1904556"(L-tryptophan transmembrane transport)|go:"GO:1990184"(amino acid transport complex)|interpro:IPR002293(Amino acid/polyamine transporter I)|interpro:IPR004760(L-type amino acid transporter)|mint:Q01650|rcsb pdb:6IRS|rcsb pdb:6IRT|rcsb pdb:6JMQ|rcsb pdb:7DSK|rcsb pdb:7DSL|rcsb pdb:7DSN|rcsb pdb:7DSQ|reactome:R-HSA-210991|reactome:R-HSA-352230|reactome:R-HSA-71240|go:"GO:0015804"(neutral amino acid transport) - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yKfTQw98LCuMIwB4Sm99uB24QUU9606 rogid:GrXTCUhrHMNCnvscgx1ink2opoU9606 rigid:fr6O3PoYpW1jB+8U8AKqMqOjga8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N5Y8 uniprotkb:O00264 intact:EBI-10266912|uniprotkb:Q9NX03|uniprotkb:Q6PK64|uniprotkb:A0A024R5Y7|ensembl:ENSP00000496935 intact:EBI-1045534|uniprotkb:Q9UGJ9|ensembl:ENSP00000217971|uniprotkb:B7Z1L3 psi-mi:par16_human(display_long)|uniprotkb:PARP16(gene name)|psi-mi:PARP16(display_short)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 15(gene name synonym)|uniprotkb:ARTD15(gene name synonym)|uniprotkb:C15orf30(gene name synonym)|uniprotkb:Poly [ADP-ribose] polymerase 16(gene name synonym) psi-mi:pgrc1_human(display_long)|uniprotkb:Dap1(gene name synonym)|uniprotkb:IZA(gene name synonym)|uniprotkb:PGRMC1(gene name)|psi-mi:PGRMC1(display_short)|uniprotkb:HPR6.6(gene name synonym)|uniprotkb:PGRMC(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482187|imex:IM-26985-117 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001303872.1|refseq:NP_001303873.1|refseq:NP_060321.3|ensembl:ENSG00000138617(gene)|ensembl:ENST00000649807(transcript)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0019900"(kinase binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0034356"(NAD biosynthesis via nicotinamide riboside salvage pathway)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070213"(protein auto-ADP-ribosylation)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0140289"(protein mono-ADP-ribosylation)|go:"GO:1990404"(protein ADP-ribosylase activity)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR041400|mint:Q8N5Y8|rcsb pdb:4F0D|rcsb pdb:6HXR|rcsb pdb:6HXS|rcsb pdb:6W65|reactome:R-HSA-197264|reactome:R-HSA-9683610|reactome:R-HSA-9694631 refseq:NP_001269550.1|ensembl:ENST00000217971(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005496"(steroid binding)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006783"(heme biosynthetic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0020037"(heme binding)|go:"GO:0030868"(smooth endoplasmic reticulum membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|interpro:IPR001199(Cytochrome b5)|interpro:IPR036400|mint:O00264|rcsb pdb:4X8Y|reactome:R-HSA-6798695|ensembl:ENSG00000101856(gene)|refseq:NP_006658.1 - - comment:"author score: 34" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yKfTQw98LCuMIwB4Sm99uB24QUU9606 rogid:fjKpwgj9042mPhLsvS/wu1wBEi89606 rigid:fr6O3PoYpW1jB+8U8AKqMqOjga8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UM07 uniprotkb:Q92665 intact:EBI-1042511|uniprotkb:Q5VTZ8|uniprotkb:Q70SX4|uniprotkb:A8K392|uniprotkb:B2RBW0|ensembl:ENSP00000364597|ensembl:ENSP00000487021 intact:EBI-720602|uniprotkb:Q8WTV8|uniprotkb:Q5VYC8|uniprotkb:B2RCS3|ensembl:ENSP00000315397 psi-mi:padi4_human(display_long)|uniprotkb:PADI4(gene name)|psi-mi:PADI4(display_short)|uniprotkb:PADI5(gene name synonym)|uniprotkb:PDI5(gene name synonym)|uniprotkb:Protein-arginine deiminase type IV(gene name synonym)|uniprotkb:Peptidylarginine deiminase IV(gene name synonym)|uniprotkb:HL-60 PAD(gene name synonym)|uniprotkb:PAD4(gene name synonym) psi-mi:rt31_human(display_long)|uniprotkb:Imogen 38(gene name synonym)|uniprotkb:MRPS31(gene name)|psi-mi:MRPS31(display_short)|uniprotkb:IMOGN38(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS31(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482106|imex:IM-26985-559 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036519.2|ensembl:ENSG00000159339(gene)|ensembl:ENSG00000280908(gene)|ensembl:ENST00000375448(transcript)|ensembl:ENST00000628229(transcript)|go:"GO:0004668"(protein-arginine deiminase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0018101"(protein citrullination)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034618"(arginine binding)|go:"GO:0036413"(histone H3-R26 citrullination)|go:"GO:0036414"(histone citrullination)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR004303(Protein-arginine deiminase)|interpro:IPR008972(Cupredoxin)|interpro:IPR013530(Protein-arginine deiminase, C-terminal)|interpro:IPR013732("Protein-arginine deiminase (PAD) N-terminal")|interpro:IPR013733("Protein-arginine deiminase (PAD) central region")|interpro:IPR036556|interpro:IPR038685|mint:Q9UM07|rcsb pdb:1WD8|rcsb pdb:1WD9|rcsb pdb:1WDA|rcsb pdb:2DEW|rcsb pdb:2DEX|rcsb pdb:2DEY|rcsb pdb:2DW5|rcsb pdb:3APM|rcsb pdb:3APN|rcsb pdb:3B1T|rcsb pdb:3B1U|rcsb pdb:4DKT|rcsb pdb:4X8C|rcsb pdb:4X8G|rcsb pdb:5N0M|rcsb pdb:5N0Y|rcsb pdb:5N0Z|rcsb pdb:5N1B|reactome:R-HSA-3247509|dip:DIP-50397N refseq:NP_005821.2|ensembl:ENSG00000102738(gene)|ensembl:ENST00000323563(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0019904"(protein domain specific binding)|interpro:IPR026299|mint:Q92665|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wr0T9z51tfvyT0h062Juwgnn3jM9606 rogid:Le0Lq+WW56dP5NLuMB2eKFeg6b09606 rigid:dKEDrm3bFkOgIMRFTQ/M9ai15+s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UM07 uniprotkb:P82650 intact:EBI-1042511|uniprotkb:Q5VTZ8|uniprotkb:Q70SX4|uniprotkb:A8K392|uniprotkb:B2RBW0|ensembl:ENSP00000364597|ensembl:ENSP00000487021 intact:EBI-1050752|ensembl:ENSP00000418008|ensembl:ENSP00000505414|uniprotkb:Q9H3I1 psi-mi:padi4_human(display_long)|uniprotkb:PADI4(gene name)|psi-mi:PADI4(display_short)|uniprotkb:PADI5(gene name synonym)|uniprotkb:PDI5(gene name synonym)|uniprotkb:Protein-arginine deiminase type IV(gene name synonym)|uniprotkb:Peptidylarginine deiminase IV(gene name synonym)|uniprotkb:HL-60 PAD(gene name synonym)|uniprotkb:PAD4(gene name synonym) psi-mi:rt22_human(display_long)|uniprotkb:MRPS22(gene name)|psi-mi:MRPS22(display_short)|uniprotkb:C3orf5(gene name synonym)|uniprotkb:RPMS22(gene name synonym)|uniprotkb:GK002(orf name)|uniprotkb:Mitochondrial small ribosomal subunit protein mS22(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482106|imex:IM-26985-559 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036519.2|ensembl:ENSG00000159339(gene)|ensembl:ENSG00000280908(gene)|ensembl:ENST00000375448(transcript)|ensembl:ENST00000628229(transcript)|go:"GO:0004668"(protein-arginine deiminase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0018101"(protein citrullination)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034618"(arginine binding)|go:"GO:0036413"(histone H3-R26 citrullination)|go:"GO:0036414"(histone citrullination)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR004303(Protein-arginine deiminase)|interpro:IPR008972(Cupredoxin)|interpro:IPR013530(Protein-arginine deiminase, C-terminal)|interpro:IPR013732("Protein-arginine deiminase (PAD) N-terminal")|interpro:IPR013733("Protein-arginine deiminase (PAD) central region")|interpro:IPR036556|interpro:IPR038685|mint:Q9UM07|rcsb pdb:1WD8|rcsb pdb:1WD9|rcsb pdb:1WDA|rcsb pdb:2DEW|rcsb pdb:2DEX|rcsb pdb:2DEY|rcsb pdb:2DW5|rcsb pdb:3APM|rcsb pdb:3APN|rcsb pdb:3B1T|rcsb pdb:3B1U|rcsb pdb:4DKT|rcsb pdb:4X8C|rcsb pdb:4X8G|rcsb pdb:5N0M|rcsb pdb:5N0Y|rcsb pdb:5N0Z|rcsb pdb:5N1B|reactome:R-HSA-3247509|dip:DIP-50397N refseq:NP_064576.1|ensembl:ENSG00000175110(gene)|ensembl:ENST00000495075(transcript)|ensembl:ENST00000680020(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|interpro:IPR019374|mint:P82650|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wr0T9z51tfvyT0h062Juwgnn3jM9606 rogid:T0htF4/rvOZUZ3RcuCjWvEg9iTE9606 rigid:dKEDrm3bFkOgIMRFTQ/M9ai15+s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UM07 uniprotkb:P50990 intact:EBI-1042511|uniprotkb:Q5VTZ8|uniprotkb:Q70SX4|uniprotkb:A8K392|uniprotkb:B2RBW0|ensembl:ENSP00000364597|ensembl:ENSP00000487021 intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788 psi-mi:padi4_human(display_long)|uniprotkb:PADI4(gene name)|psi-mi:PADI4(display_short)|uniprotkb:PADI5(gene name synonym)|uniprotkb:PDI5(gene name synonym)|uniprotkb:Protein-arginine deiminase type IV(gene name synonym)|uniprotkb:Peptidylarginine deiminase IV(gene name synonym)|uniprotkb:HL-60 PAD(gene name synonym)|uniprotkb:PAD4(gene name synonym) psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482106|imex:IM-26985-559 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036519.2|ensembl:ENSG00000159339(gene)|ensembl:ENSG00000280908(gene)|ensembl:ENST00000375448(transcript)|ensembl:ENST00000628229(transcript)|go:"GO:0004668"(protein-arginine deiminase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0018101"(protein citrullination)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034618"(arginine binding)|go:"GO:0036413"(histone H3-R26 citrullination)|go:"GO:0036414"(histone citrullination)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR004303(Protein-arginine deiminase)|interpro:IPR008972(Cupredoxin)|interpro:IPR013530(Protein-arginine deiminase, C-terminal)|interpro:IPR013732("Protein-arginine deiminase (PAD) N-terminal")|interpro:IPR013733("Protein-arginine deiminase (PAD) central region")|interpro:IPR036556|interpro:IPR038685|mint:Q9UM07|rcsb pdb:1WD8|rcsb pdb:1WD9|rcsb pdb:1WDA|rcsb pdb:2DEW|rcsb pdb:2DEX|rcsb pdb:2DEY|rcsb pdb:2DW5|rcsb pdb:3APM|rcsb pdb:3APN|rcsb pdb:3B1T|rcsb pdb:3B1U|rcsb pdb:4DKT|rcsb pdb:4X8C|rcsb pdb:4X8G|rcsb pdb:5N0M|rcsb pdb:5N0Y|rcsb pdb:5N0Z|rcsb pdb:5N1B|reactome:R-HSA-3247509|dip:DIP-50397N refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wr0T9z51tfvyT0h062Juwgnn3jM9606 rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606 rigid:dKEDrm3bFkOgIMRFTQ/M9ai15+s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UM07 uniprotkb:P82921 intact:EBI-1042511|uniprotkb:Q5VTZ8|uniprotkb:Q70SX4|uniprotkb:A8K392|uniprotkb:B2RBW0|ensembl:ENSP00000364597|ensembl:ENSP00000487021 intact:EBI-2372155|uniprotkb:Q9BST6|uniprotkb:A0A075B746|uniprotkb:Q5TB11|ensembl:ENSP00000461930|ensembl:ENSP00000480129 psi-mi:padi4_human(display_long)|uniprotkb:PADI4(gene name)|psi-mi:PADI4(display_short)|uniprotkb:PADI5(gene name synonym)|uniprotkb:PDI5(gene name synonym)|uniprotkb:Protein-arginine deiminase type IV(gene name synonym)|uniprotkb:Peptidylarginine deiminase IV(gene name synonym)|uniprotkb:HL-60 PAD(gene name synonym)|uniprotkb:PAD4(gene name synonym) psi-mi:rt21_human(display_long)|uniprotkb:MRPS21(gene name)|psi-mi:MRPS21(display_short)|uniprotkb:RPMS21(gene name synonym)|uniprotkb:MDS016(orf name)|uniprotkb:Mitochondrial small ribosomal subunit protein bS21m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482106|imex:IM-26985-559 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036519.2|ensembl:ENSG00000159339(gene)|ensembl:ENSG00000280908(gene)|ensembl:ENST00000375448(transcript)|ensembl:ENST00000628229(transcript)|go:"GO:0004668"(protein-arginine deiminase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0018101"(protein citrullination)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034618"(arginine binding)|go:"GO:0036413"(histone H3-R26 citrullination)|go:"GO:0036414"(histone citrullination)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR004303(Protein-arginine deiminase)|interpro:IPR008972(Cupredoxin)|interpro:IPR013530(Protein-arginine deiminase, C-terminal)|interpro:IPR013732("Protein-arginine deiminase (PAD) N-terminal")|interpro:IPR013733("Protein-arginine deiminase (PAD) central region")|interpro:IPR036556|interpro:IPR038685|mint:Q9UM07|rcsb pdb:1WD8|rcsb pdb:1WD9|rcsb pdb:1WDA|rcsb pdb:2DEW|rcsb pdb:2DEX|rcsb pdb:2DEY|rcsb pdb:2DW5|rcsb pdb:3APM|rcsb pdb:3APN|rcsb pdb:3B1T|rcsb pdb:3B1U|rcsb pdb:4DKT|rcsb pdb:4X8C|rcsb pdb:4X8G|rcsb pdb:5N0M|rcsb pdb:5N0Y|rcsb pdb:5N0Z|rcsb pdb:5N1B|reactome:R-HSA-3247509|dip:DIP-50397N refseq:NP_061870.1|refseq:NP_114107.1|ensembl:ENSG00000266472(gene)|ensembl:ENST00000581066(transcript)|ensembl:ENST00000614145(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR001911(Ribosomal protein S21)|interpro:IPR038380|mint:P82921|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wr0T9z51tfvyT0h062Juwgnn3jM9606 rogid:AGyHmum6PLo+BxY+wgQvG2894A49606 rigid:dKEDrm3bFkOgIMRFTQ/M9ai15+s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UM07 uniprotkb:Q96IJ6 intact:EBI-1042511|uniprotkb:Q5VTZ8|uniprotkb:Q70SX4|uniprotkb:A8K392|uniprotkb:B2RBW0|ensembl:ENSP00000364597|ensembl:ENSP00000487021 intact:EBI-750953|uniprotkb:A6NJ74|uniprotkb:A8K3Q6|uniprotkb:Q53GI0|uniprotkb:Q9NWC3|uniprotkb:Q9Y5P5|uniprotkb:B3KMT4|ensembl:ENSP00000315925|ensembl:ENSP00000340760|ensembl:ENSP00000350949|ensembl:ENSP00000363016|ensembl:ENSP00000478700|ensembl:ENSP00000506941 psi-mi:padi4_human(display_long)|uniprotkb:PADI4(gene name)|psi-mi:PADI4(display_short)|uniprotkb:PADI5(gene name synonym)|uniprotkb:PDI5(gene name synonym)|uniprotkb:Protein-arginine deiminase type IV(gene name synonym)|uniprotkb:Peptidylarginine deiminase IV(gene name synonym)|uniprotkb:HL-60 PAD(gene name synonym)|uniprotkb:PAD4(gene name synonym) psi-mi:gmppa_human(display_long)|uniprotkb:GMPPA(gene name)|psi-mi:GMPPA(display_short)|uniprotkb:GTP-mannose-1-phosphate guanylyltransferase alpha(gene name synonym)|uniprotkb:GDP-mannose pyrophosphorylase A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482106|imex:IM-26985-559 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036519.2|ensembl:ENSG00000159339(gene)|ensembl:ENSG00000280908(gene)|ensembl:ENST00000375448(transcript)|ensembl:ENST00000628229(transcript)|go:"GO:0004668"(protein-arginine deiminase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0018101"(protein citrullination)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034618"(arginine binding)|go:"GO:0036413"(histone H3-R26 citrullination)|go:"GO:0036414"(histone citrullination)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|interpro:IPR004303(Protein-arginine deiminase)|interpro:IPR008972(Cupredoxin)|interpro:IPR013530(Protein-arginine deiminase, C-terminal)|interpro:IPR013732("Protein-arginine deiminase (PAD) N-terminal")|interpro:IPR013733("Protein-arginine deiminase (PAD) central region")|interpro:IPR036556|interpro:IPR038685|mint:Q9UM07|rcsb pdb:1WD8|rcsb pdb:1WD9|rcsb pdb:1WDA|rcsb pdb:2DEW|rcsb pdb:2DEX|rcsb pdb:2DEY|rcsb pdb:2DW5|rcsb pdb:3APM|rcsb pdb:3APN|rcsb pdb:3B1T|rcsb pdb:3B1U|rcsb pdb:4DKT|rcsb pdb:4X8C|rcsb pdb:4X8G|rcsb pdb:5N0M|rcsb pdb:5N0Y|rcsb pdb:5N0Z|rcsb pdb:5N1B|reactome:R-HSA-3247509|dip:DIP-50397N refseq:NP_037467.2|refseq:NP_995319.1|refseq:XP_005246543.1|refseq:XP_016859398.1|refseq:XP_016859399.1|refseq:XP_016859400.1|ensembl:ENSG00000144591(gene)|ensembl:ENST00000313597(transcript)|ensembl:ENST00000341142(transcript)|ensembl:ENST00000358215(transcript)|ensembl:ENST00000373908(transcript)|ensembl:ENST00000622191(transcript)|ensembl:ENST00000683946(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0009058"(biosynthetic process)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001451(Bacterial transferase hexapeptide repeat)|interpro:IPR005835(Nucleotidyl transferase)|interpro:IPR018357|interpro:IPR029044|mint:Q96IJ6|rcsb pdb:7D72|rcsb pdb:7D73|rcsb pdb:7D74|reactome:R-HSA-446205 - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wr0T9z51tfvyT0h062Juwgnn3jM9606 rogid:ASWzJoQB8W+e2OKYEenXpUJxflI9606 rigid:dKEDrm3bFkOgIMRFTQ/M9ai15+s false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75607 uniprotkb:Q9H4L4 intact:EBI-721544|uniprotkb:Q9UNY6|intact:EBI-28974425|ensembl:ENSP00000359128 intact:EBI-2880236|ensembl:ENSP00000314029|ensembl:ENSP00000403712|uniprotkb:Q96PS4|uniprotkb:Q66K15|uniprotkb:Q86VS7|uniprotkb:Q9Y3W9 psi-mi:npm3_human(display_long)|uniprotkb:NPM3(gene name)|psi-mi:NPM3(display_short) psi-mi:senp3_human(display_long)|uniprotkb:SENP3(gene name)|psi-mi:SENP3(display_short)|uniprotkb:SSP3(gene name synonym)|uniprotkb:SUSP3(gene name synonym)|uniprotkb:SUMO-1-specific protease 3(gene name synonym)|uniprotkb:Sentrin/SUMO-specific protease SENP3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481968|imex:IM-26985-415 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008924.1|ensembl:ENSP00000359128|ensembl:ENSG00000107833(gene)|ensembl:ENST00000370110(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0009303"(rRNA transcription)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0042393"(histone binding)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR036824|mint:O75607 ensembl:ENSG00000161956(gene)|ensembl:ENST00000321337(transcript)|ensembl:ENST00000429205(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0016926"(protein desumoylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR003653(Peptidase C48, SUMO/Sentrin/Ubl1)|interpro:IPR037945|interpro:IPR038765|mint:Q9H4L4|reactome:R-HSA-6791226|refseq:NP_056485.2|dip:DIP-47511N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lryH+qFG3/zmXWyn25dmU44prpk9606 rogid:sE4k87ORoxSjBkbccPsXLYzuqII9606 rigid:Qhqedyyj/Y617inKhjB75dhEEmE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75607 uniprotkb:Q5SY16 intact:EBI-721544|uniprotkb:Q9UNY6|intact:EBI-28974425|ensembl:ENSP00000359128 intact:EBI-1055462|uniprotkb:Q4VBY3|uniprotkb:Q6P472|uniprotkb:Q7L4D6|uniprotkb:Q96EE0|uniprotkb:Q9H5L4|uniprotkb:Q2NL84|ensembl:ENSP00000366934 psi-mi:npm3_human(display_long)|uniprotkb:NPM3(gene name)|psi-mi:NPM3(display_short) psi-mi:nol9_human(display_long)|uniprotkb:NOL9(gene name)|psi-mi:NOL9(display_short)|uniprotkb:Nucleolar protein 9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481968|imex:IM-26985-415 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008924.1|ensembl:ENSP00000359128|ensembl:ENSG00000107833(gene)|ensembl:ENST00000370110(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0009303"(rRNA transcription)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0042393"(histone binding)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR036824|mint:O75607 refseq:NP_078930.3|refseq:XP_011540449.1|ensembl:ENST00000377705(transcript)|go:"GO:0000448"("cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006396"(RNA processing)|go:"GO:0016020"(membrane)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0051731"(polynucleotide 5'-hydroxyl-kinase activity)|interpro:IPR027417|interpro:IPR032319|mint:Q5SY16|reactome:R-HSA-6791226|ensembl:ENSG00000162408(gene)|refseq:XP_016857827.1|refseq:XP_016857828.1 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lryH+qFG3/zmXWyn25dmU44prpk9606 rogid:IWGhuh/G+MlTxlSXEcIml8tvK7Y9606 rigid:Qhqedyyj/Y617inKhjB75dhEEmE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75607 uniprotkb:O00505 intact:EBI-721544|uniprotkb:Q9UNY6|intact:EBI-28974425|ensembl:ENSP00000359128 intact:EBI-358297|intact:EBI-28976892|ensembl:ENSP00000261667|uniprotkb:O00191|uniprotkb:O43195|uniprotkb:Q96AA7|uniprotkb:Q5JVM9|intact:EBI-742146|uniprotkb:Q8IYQ9 psi-mi:npm3_human(display_long)|uniprotkb:NPM3(gene name)|psi-mi:NPM3(display_short) psi-mi:ima4_human(display_long)|uniprotkb:KPNA3(gene name)|psi-mi:KPNA3(display_short)|uniprotkb:QIP2(gene name synonym)|uniprotkb:Karyopherin subunit alpha-3(gene name synonym)|uniprotkb:SRP1-gamma(gene name synonym)|uniprotkb:Importin alpha Q2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481968|imex:IM-26985-415 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008924.1|ensembl:ENSP00000359128|ensembl:ENSG00000107833(gene)|ensembl:ENST00000370110(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0009303"(rRNA transcription)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0042393"(histone binding)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR036824|mint:O75607 ensembl:ENSG00000102753(gene)|ensembl:ENST00000261667(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0043657"(host cell)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR000225(Armadillo)|refseq:NP_002258.2|ensembl:ENSP00000261667|dip:DIP-27586N|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O00505|reactome:R-HSA-1169408|reactome:R-HSA-168276 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lryH+qFG3/zmXWyn25dmU44prpk9606 rogid:kx/oTYWMYG7dhwJHvr1POLD6FTU9606 rigid:Qhqedyyj/Y617inKhjB75dhEEmE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75607 uniprotkb:Q9UN30 intact:EBI-721544|uniprotkb:Q9UNY6|intact:EBI-28974425|ensembl:ENSP00000359128 intact:EBI-6911404|ensembl:ENSP00000369380|uniprotkb:B2RA08|uniprotkb:Q5H969|uniprotkb:B0FZN6|uniprotkb:Q5H968 psi-mi:npm3_human(display_long)|uniprotkb:NPM3(gene name)|psi-mi:NPM3(display_short) psi-mi:scml1_human(display_long)|uniprotkb:SCML1(gene name)|psi-mi:SCML1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481968|imex:IM-26985-415 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008924.1|ensembl:ENSP00000359128|ensembl:ENSG00000107833(gene)|ensembl:ENST00000370110(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0009303"(rRNA transcription)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0042393"(histone binding)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR036824|mint:O75607 ensembl:ENSG00000047634(gene)|ensembl:ENST00000380041(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|mint:Q9UN30|refseq:XP_016885212.1|refseq:XP_006724571.1|refseq:NP_001032624.1|refseq:NP_001032625.1|refseq:NP_001032629.1|refseq:NP_006737.2 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lryH+qFG3/zmXWyn25dmU44prpk9606 rogid:/eJ/2Xuw4P5GzHy1wGRxnYZ4hvY9606 rigid:Qhqedyyj/Y617inKhjB75dhEEmE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75607 uniprotkb:Q8IZL8 intact:EBI-721544|uniprotkb:Q9UNY6|intact:EBI-28974425|ensembl:ENSP00000359128 intact:EBI-716449|intact:EBI-28969510|ensembl:ENSP00000460300|ensembl:ENSP00000461625|uniprotkb:O15450|uniprotkb:Q5EGN3|uniprotkb:Q6NTE6|uniprotkb:Q96FT1|uniprotkb:Q9BU60 psi-mi:npm3_human(display_long)|uniprotkb:NPM3(gene name)|psi-mi:NPM3(display_short) psi-mi:pelp1_human(display_long)|uniprotkb:Modulator of non-genomic activity of estrogen receptor(gene name synonym)|uniprotkb:Transcription factor HMX3(gene name synonym)|uniprotkb:PELP1(gene name)|psi-mi:PELP1(display_short)|uniprotkb:HMX3(gene name synonym)|uniprotkb:MNAR(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481968|imex:IM-26985-415 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008924.1|ensembl:ENSP00000359128|ensembl:ENSG00000107833(gene)|ensembl:ENST00000370110(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0009303"(rRNA transcription)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0042393"(histone binding)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR036824|mint:O75607 ensembl:ENSG00000141456(gene)|ensembl:ENST00000572293(transcript)|ensembl:ENST00000574876(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0035327"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071391"(cellular response to estrogen stimulus)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012583(NUC201)|interpro:IPR016024(Armadillo-type fold)|mint:Q8IZL8|reactome:R-HSA-6791226|reactome:R-HSA-8849473|interpro:IPR012980(Protein of unknown function NUC202)|ensembl:ENSP00000460300|ensembl:ENSP00000461625|refseq:NP_055204.3|refseq:NP_001265170.1 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lryH+qFG3/zmXWyn25dmU44prpk9606 rogid:iu03DsintVoo3gWzZX14SlHE0ao9606 rigid:Qhqedyyj/Y617inKhjB75dhEEmE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75607 uniprotkb:P61313 intact:EBI-721544|uniprotkb:Q9UNY6|intact:EBI-28974425|ensembl:ENSP00000359128 intact:EBI-443462|ensembl:ENSP00000309334|ensembl:ENSP00000346867|ensembl:ENSP00000388529|ensembl:ENSP00000416692|ensembl:ENSP00000483260|ensembl:ENSP00000493759|uniprotkb:Q642I1|uniprotkb:Q9H2E5|uniprotkb:P39030|uniprotkb:P41051|uniprotkb:Q6IPX6|uniprotkb:Q8WYP2|uniprotkb:Q96C44|uniprotkb:Q5U0C0|intact:EBI-2877712 psi-mi:npm3_human(display_long)|uniprotkb:NPM3(gene name)|psi-mi:NPM3(display_short) psi-mi:rl15_human(display_long)|uniprotkb:RPL15(gene name)|psi-mi:RPL15(display_short)|uniprotkb:EC45(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL15(gene name synonym)|uniprotkb:TCBAP0781(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481968|imex:IM-26985-415 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008924.1|ensembl:ENSP00000359128|ensembl:ENSG00000107833(gene)|ensembl:ENST00000370110(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0009303"(rRNA transcription)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0042393"(histone binding)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR036824|mint:O75607 ensembl:ENSG00000174748(gene)|ensembl:ENST00000307839(transcript)|ensembl:ENST00000354811(transcript)|ensembl:ENST00000413699(transcript)|ensembl:ENST00000415719(transcript)|ensembl:ENST00000611050(transcript)|ensembl:ENST00000644185(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031672"(A band)|go:"GO:0045296"(cadherin binding)|go:"GO:0045471"(response to ethanol)|interpro:IPR000439(Ribosomal protein L15e)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR020925|interpro:IPR024794|mint:P61313|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_002939.2|refseq:NP_001240308.1|refseq:NP_001240309.1|refseq:NP_001240311.1|refseq:NP_001240312.1|refseq:NP_001240313.1 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lryH+qFG3/zmXWyn25dmU44prpk9606 rogid:wllGpJicgC5uwkZV6e4QRwDcrBo9606 rigid:Qhqedyyj/Y617inKhjB75dhEEmE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75607 uniprotkb:P62750 intact:EBI-721544|uniprotkb:Q9UNY6|intact:EBI-28974425|ensembl:ENSP00000359128 intact:EBI-353254|uniprotkb:P29316|uniprotkb:Q92774|uniprotkb:P39024|uniprotkb:B2R5B2|ensembl:ENSP00000389103 psi-mi:npm3_human(display_long)|uniprotkb:NPM3(gene name)|psi-mi:NPM3(display_short) psi-mi:rl23a_human(display_long)|uniprotkb:RPL23A(gene name)|psi-mi:RPL23A(display_short)|uniprotkb:Large ribosomal subunit protein uL23(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481968|imex:IM-26985-415 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008924.1|ensembl:ENSP00000359128|ensembl:ENSG00000107833(gene)|ensembl:ENST00000370110(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0009303"(rRNA transcription)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0042393"(histone binding)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR036824|mint:O75607 reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|refseq:NP_000975.2|ensembl:ENSG00000198242(gene)|ensembl:ENST00000422514(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904841"(TORC2 complex binding)|interpro:IPR001014(Ribosomal protein L23, conserved site)|interpro:IPR005633(Ribosomal protein L23/L25, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR013025(Ribosomal protein L25/L23)|interpro:IPR019985|mint:P62750|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lryH+qFG3/zmXWyn25dmU44prpk9606 rogid:lA1ubRFO9/Tl54Z1dKUzoCKvpAo9606 rigid:Qhqedyyj/Y617inKhjB75dhEEmE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75607 uniprotkb:Q9BYC9 intact:EBI-721544|uniprotkb:Q9UNY6|intact:EBI-28974425|ensembl:ENSP00000359128 intact:EBI-714361|uniprotkb:B2RE41|ensembl:ENSP00000341082|uniprotkb:B7Z746 psi-mi:npm3_human(display_long)|uniprotkb:NPM3(gene name)|psi-mi:NPM3(display_short) psi-mi:rm20_human(display_long)|uniprotkb:MRPL20(gene name)|psi-mi:MRPL20(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein bL20m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481968|imex:IM-26985-415 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008924.1|ensembl:ENSP00000359128|ensembl:ENSG00000107833(gene)|ensembl:ENST00000370110(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0009303"(rRNA transcription)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0042393"(histone binding)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR036824|mint:O75607 rcsb pdb:7OF4|rcsb pdb:7OG4|refseq:NP_060441.2|ensembl:ENSG00000242485(gene)|ensembl:ENST00000344843(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|interpro:IPR005813(Ribosomal protein L20)|interpro:IPR035566|mint:Q9BYC9|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:6VMI|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lryH+qFG3/zmXWyn25dmU44prpk9606 rogid:x96Ntk82ZbcbF8ksg84k0sHgINc9606 rigid:Qhqedyyj/Y617inKhjB75dhEEmE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75607 uniprotkb:P62841 intact:EBI-721544|uniprotkb:Q9UNY6|intact:EBI-28974425|ensembl:ENSP00000359128 intact:EBI-372635|uniprotkb:Q3KRA1|uniprotkb:P11174|uniprotkb:A5D8V9|uniprotkb:Q9UDC2|ensembl:ENSP00000467466 psi-mi:npm3_human(display_long)|uniprotkb:NPM3(gene name)|psi-mi:NPM3(display_short) psi-mi:rs15_human(display_long)|uniprotkb:RIG protein(gene name synonym)|uniprotkb:RPS15(gene name)|psi-mi:RPS15(display_short)|uniprotkb:RIG(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS19(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481968|imex:IM-26985-415 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008924.1|ensembl:ENSP00000359128|ensembl:ENSG00000107833(gene)|ensembl:ENST00000370110(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0009303"(rRNA transcription)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0042393"(histone binding)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR036824|mint:O75607 refseq:NP_001009.1|mint:P62841|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|ensembl:ENSG00000115268(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|ensembl:ENST00000592588(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0045202"(synapse)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0097421"(liver regeneration)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|interpro:IPR002222(Ribosomal protein S19/S15)|interpro:IPR005713(Ribosomal protein S15, eukaryotic/archaeal)|interpro:IPR020934|go:"GO:0003735"(structural constituent of ribosome)|interpro:IPR023575|rcsb pdb:6ZVH|rcsb pdb:6ZMT|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|rcsb pdb:6ZMW|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lryH+qFG3/zmXWyn25dmU44prpk9606 rogid:lJJOew1txuTwFlhKu4Z+AkPS5H09606 rigid:Qhqedyyj/Y617inKhjB75dhEEmE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75607 uniprotkb:Q02878 intact:EBI-721544|uniprotkb:Q9UNY6|intact:EBI-28974425|ensembl:ENSP00000359128 intact:EBI-359655|uniprotkb:Q2M3Q3|uniprotkb:Q8WW97|ensembl:ENSP00000202773|ensembl:ENSP00000403172 psi-mi:npm3_human(display_long)|uniprotkb:NPM3(gene name)|psi-mi:NPM3(display_short) psi-mi:rl6_human(display_long)|uniprotkb:RPL6(gene name)|psi-mi:RPL6(display_short)|uniprotkb:TXREB1(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 107(gene name synonym)|uniprotkb:Neoplasm-related protein C140(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481968|imex:IM-26985-415 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008924.1|ensembl:ENSP00000359128|ensembl:ENSG00000107833(gene)|ensembl:ENST00000370110(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0009303"(rRNA transcription)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0042393"(histone binding)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR036824|mint:O75607 refseq:NP_000961.2|refseq:NP_001019833.1|ensembl:ENSG00000089009(gene)|ensembl:ENST00000202773(transcript)|ensembl:ENST00000424576(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR000915(Ribosomal protein L6E)|interpro:IPR005568(Ribosomal protein L6, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041997|mint:Q02878|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001307066.1|refseq:NP_001307067.1|refseq:NP_001307068.1|refseq:NP_001307069.1|refseq:NP_001307070.1|refseq:XP_016875270.1|refseq:XP_016875271.1|dip:DIP-27547N - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lryH+qFG3/zmXWyn25dmU44prpk9606 rogid:Y7fx3ToInzucV2QmI8KLSdHxai09606 rigid:Qhqedyyj/Y617inKhjB75dhEEmE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75607 uniprotkb:Q9BV38 intact:EBI-721544|uniprotkb:Q9UNY6|intact:EBI-28974425|ensembl:ENSP00000359128 intact:EBI-727429|uniprotkb:O60390|uniprotkb:Q9BWR2|intact:EBI-28969560|ensembl:ENSP00000476117 psi-mi:npm3_human(display_long)|uniprotkb:NPM3(gene name)|psi-mi:NPM3(display_short) psi-mi:wdr18_human(display_long)|uniprotkb:WDR18(gene name)|psi-mi:WDR18(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481968|imex:IM-26985-415 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008924.1|ensembl:ENSP00000359128|ensembl:ENSG00000107833(gene)|ensembl:ENST00000370110(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0009303"(rRNA transcription)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0042393"(histone binding)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR036824|mint:O75607 refseq:NP_077005.2|ensembl:ENSP00000476117|go:"GO:0097344"(Rix1 complex)|go:"GO:0120293"(dynein axonemal particle)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR026987|interpro:IPR036322|mint:Q9BV38|reactome:R-HSA-6791226|ensembl:ENSG00000065268(gene)|ensembl:ENST00000585809(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005656"(nuclear pre-replicative complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation) - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lryH+qFG3/zmXWyn25dmU44prpk9606 rogid:03RKz4c6MKJvOePaNrKeInnS6Lg9606 rigid:Qhqedyyj/Y617inKhjB75dhEEmE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75607 uniprotkb:Q9UMY1 intact:EBI-721544|uniprotkb:Q9UNY6|intact:EBI-28974425|ensembl:ENSP00000359128 intact:EBI-2862609|uniprotkb:Q9Y3U7|uniprotkb:Q5T297|ensembl:ENSP00000405674 psi-mi:npm3_human(display_long)|uniprotkb:NPM3(gene name)|psi-mi:NPM3(display_short) psi-mi:nol7_human(display_long)|uniprotkb:NOL7(gene name)|psi-mi:NOL7(display_short)|uniprotkb:C6orf90(gene name synonym)|uniprotkb:NOP27(gene name synonym)|uniprotkb:Nucleolar protein of 27 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481968|imex:IM-26985-415 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008924.1|ensembl:ENSP00000359128|ensembl:ENSG00000107833(gene)|ensembl:ENST00000370110(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0009303"(rRNA transcription)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0042393"(histone binding)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR036824|mint:O75607 refseq:NP_057251.2|refseq:NP_001304653.1|ensembl:ENSG00000225921(gene)|ensembl:ENST00000451315(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|interpro:IPR012579(NUC129)|interpro:IPR039626|mint:Q9UMY1 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lryH+qFG3/zmXWyn25dmU44prpk9606 rogid:4I1C2wd0qGg9CWZDodm/Bp+tptA9606 rigid:Qhqedyyj/Y617inKhjB75dhEEmE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75607 uniprotkb:Q9NXF1 intact:EBI-721544|uniprotkb:Q9UNY6|intact:EBI-28974425|ensembl:ENSP00000359128 intact:EBI-2371062|uniprotkb:Q5T722|uniprotkb:Q5T723|uniprotkb:Q8NCN8|uniprotkb:Q8TDY0|uniprotkb:B4DYV2|ensembl:ENSP00000364037 psi-mi:npm3_human(display_long)|uniprotkb:NPM3(gene name)|psi-mi:NPM3(display_short) psi-mi:tex10_human(display_long)|uniprotkb:TEX10(gene name)|psi-mi:TEX10(display_short)|uniprotkb:L18(orf name)|uniprotkb:Nbla10363(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481968|imex:IM-26985-415 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008924.1|ensembl:ENSP00000359128|ensembl:ENSG00000107833(gene)|ensembl:ENST00000370110(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0009303"(rRNA transcription)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0042393"(histone binding)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR036824|mint:O75607 refseq:NP_060216.2|refseq:NP_001155056.1|ensembl:ENSG00000136891(gene)|ensembl:ENST00000374902(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0071339"(MLL1 complex)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR024679|interpro:IPR037947|mint:Q9NXF1|reactome:R-HSA-6791226 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lryH+qFG3/zmXWyn25dmU44prpk9606 rogid:cQcRo1eExRkr/an7wvBN8Ttyatc9606 rigid:Qhqedyyj/Y617inKhjB75dhEEmE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75607 uniprotkb:Q9Y4W2 intact:EBI-721544|uniprotkb:Q9UNY6|intact:EBI-28974425|ensembl:ENSP00000359128 intact:EBI-1051591|uniprotkb:Q5JXQ0|uniprotkb:Q8TEN5|uniprotkb:Q9H9V5|uniprotkb:A9X410|ensembl:ENSP00000363944 psi-mi:npm3_human(display_long)|uniprotkb:NPM3(gene name)|psi-mi:NPM3(display_short) psi-mi:las1l_human(display_long)|uniprotkb:LAS1L(gene name)|psi-mi:LAS1L(display_short)|uniprotkb:Protein LAS1 homolog(gene name synonym)|uniprotkb:MSTP060(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481968|imex:IM-26985-415 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008924.1|ensembl:ENSP00000359128|ensembl:ENSG00000107833(gene)|ensembl:ENST00000370110(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0009303"(rRNA transcription)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0042393"(histone binding)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR036824|mint:O75607 refseq:NP_001164120.1|refseq:NP_001164121.1|refseq:NP_112483.1|ensembl:ENSG00000001497(gene)|ensembl:ENST00000374811(transcript)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090730"(Las1 complex)|interpro:IPR007174(Las1-like)|mint:Q9Y4W2|reactome:R-HSA-6791226 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lryH+qFG3/zmXWyn25dmU44prpk9606 rogid:1TTE2TCMIwczNaT2SSMLioLkALA9606 rigid:Qhqedyyj/Y617inKhjB75dhEEmE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75607 uniprotkb:Q9NRX1 intact:EBI-721544|uniprotkb:Q9UNY6|intact:EBI-28974425|ensembl:ENSP00000359128 intact:EBI-712787|ensembl:ENSP00000263657|uniprotkb:Q53G13|uniprotkb:Q8WVB8|uniprotkb:A8K6Q0 psi-mi:npm3_human(display_long)|uniprotkb:NPM3(gene name)|psi-mi:NPM3(display_short) psi-mi:pno1_human(display_long)|uniprotkb:Partner of NOB1(gene name synonym)|uniprotkb:PNO1(gene name)|psi-mi:PNO1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481968|imex:IM-26985-415 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008924.1|ensembl:ENSP00000359128|ensembl:ENSG00000107833(gene)|ensembl:ENST00000370110(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0009303"(rRNA transcription)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0042393"(histone binding)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR036824|mint:O75607 ensembl:ENSG00000115946(gene)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|interpro:IPR004087(K Homology)|interpro:IPR036612|interpro:IPR039912|mint:Q9NRX1|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5I|rcsb pdb:6ZUO|rcsb pdb:6ZXD|rcsb pdb:6ZXE|reactome:R-HSA-6790901|reactome:R-HSA-6791226|ensembl:ENST00000263657(transcript)|refseq:NP_064528.1 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lryH+qFG3/zmXWyn25dmU44prpk9606 rogid:zxUnBMJ/10/uydzhq1t1UaNAwmo9606 rigid:Qhqedyyj/Y617inKhjB75dhEEmE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75607 uniprotkb:Q8TDN6 intact:EBI-721544|uniprotkb:Q9UNY6|intact:EBI-28974425|ensembl:ENSP00000359128 intact:EBI-1052326|uniprotkb:Q3ZTT4|uniprotkb:Q8N453|uniprotkb:Q96DH1|uniprotkb:A8K0P5|ensembl:ENSP00000338862 psi-mi:npm3_human(display_long)|uniprotkb:NPM3(gene name)|psi-mi:NPM3(display_short) psi-mi:brx1_human(display_long)|uniprotkb:BRIX1(gene name)|psi-mi:BRIX1(display_short)|uniprotkb:BXDC2(gene name synonym)|uniprotkb:BRIX(gene name synonym)|uniprotkb:Brix domain-containing protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481968|imex:IM-26985-415 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008924.1|ensembl:ENSP00000359128|ensembl:ENSG00000107833(gene)|ensembl:ENST00000370110(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0009303"(rRNA transcription)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0042393"(histone binding)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR036824|mint:O75607 refseq:NP_060791.3|ensembl:ENSG00000113460(gene)|ensembl:ENST00000336767(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0019843"(rRNA binding)|interpro:IPR007109(Brix)|interpro:IPR026532|mint:Q8TDN6 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lryH+qFG3/zmXWyn25dmU44prpk9606 rogid:Xa2UDOXgdmWyJ7qBZsdInDt9Vaw9606 rigid:Qhqedyyj/Y617inKhjB75dhEEmE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75607 uniprotkb:P06748 intact:EBI-721544|uniprotkb:Q9UNY6|intact:EBI-28974425|ensembl:ENSP00000359128 intact:EBI-78579|uniprotkb:P08693|uniprotkb:Q12826|uniprotkb:Q13440|uniprotkb:Q13441|uniprotkb:Q14115|uniprotkb:Q5EU94|uniprotkb:Q5EU95|uniprotkb:Q5EU96|uniprotkb:Q5EU97|uniprotkb:Q5EU98|uniprotkb:Q5EU99|uniprotkb:Q6V962|uniprotkb:Q8WTW5|uniprotkb:Q96AT6|uniprotkb:Q96DC4|uniprotkb:Q96EA5|uniprotkb:A8K3N7|uniprotkb:B5BU00|uniprotkb:Q9UDJ7|uniprotkb:D3DQL6|uniprotkb:Q9BYG9|ensembl:ENSP00000296930|ensembl:ENSP00000428755 psi-mi:npm3_human(display_long)|uniprotkb:NPM3(gene name)|psi-mi:NPM3(display_short) psi-mi:npm_human(display_long)|uniprotkb:NPM1(gene name)|psi-mi:NPM1(display_short)|uniprotkb:NPM(gene name synonym)|uniprotkb:Nucleolar phosphoprotein B23(gene name synonym)|uniprotkb:Numatrin(gene name synonym)|uniprotkb:Nucleolar protein NO38(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481968|imex:IM-26985-415 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008924.1|ensembl:ENSP00000359128|ensembl:ENSG00000107833(gene)|ensembl:ENST00000370110(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0009303"(rRNA transcription)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0042393"(histone binding)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR036824|mint:O75607 refseq:NP_002511.1|refseq:NP_954654.1|refseq:NP_001032827.1|dip:DIP-30932N|ensembl:ENSG00000181163(gene)|ensembl:ENST00000296930(transcript)|ensembl:ENST00000517671(transcript)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001652"(granular component)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006407"(rRNA export from nucleus)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0010825"(positive regulation of centrosome duplication)|go:"GO:0010826"(negative regulation of centrosome duplication)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0019843"(rRNA binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030957"(Tat protein binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0032071"(regulation of endodeoxyribonuclease activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042255"(ribosome assembly)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0044387"(negative regulation of protein kinase activity by regulation of protein phosphorylation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0050821"(protein stabilization)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060699"(regulation of endoribonuclease activity)|go:"GO:0060735"(regulation of eIF2 alpha phosphorylation by dsRNA)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902629"(regulation of mRNA stability involved in cellular response to UV)|go:"GO:1902751"(positive regulation of cell cycle G2/M phase transition)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR032569|interpro:IPR036824|mint:P06748|rcsb pdb:2LLH|rcsb pdb:2P1B|rcsb pdb:2VXD|rcsb pdb:5EHD|reactome:R-HSA-180746|reactome:R-HSA-3899300|reactome:R-HSA-606279|reactome:R-HSA-6804115|reactome:R-HSA-8869496 - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lryH+qFG3/zmXWyn25dmU44prpk9606 rogid:HJ7Mg+XsIhuJiScPKiI0dIa6KpM9606 rigid:Qhqedyyj/Y617inKhjB75dhEEmE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75607 uniprotkb:Q6NW34 intact:EBI-721544|uniprotkb:Q9UNY6|intact:EBI-28974425|ensembl:ENSP00000359128 intact:EBI-2514392|ensembl:ENSP00000320251|uniprotkb:Q9H7U0|uniprotkb:Q9UFM4|uniprotkb:Q68DM6|uniprotkb:D3DN69 psi-mi:npm3_human(display_long)|uniprotkb:NPM3(gene name)|psi-mi:NPM3(display_short) psi-mi:nepro_human(display_long)|uniprotkb:NEPRO(gene name)|psi-mi:NEPRO(display_short)|uniprotkb:C3orf17(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481968|imex:IM-26985-415 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008924.1|ensembl:ENSP00000359128|ensembl:ENSG00000107833(gene)|ensembl:ENST00000370110(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0009303"(rRNA transcription)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0042393"(histone binding)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR036824|mint:O75607 refseq:NP_001306038.1|refseq:NP_001306039.1|refseq:NP_001306040.1|refseq:NP_001306041.1|refseq:NP_001306043.1|refseq:NP_001306044.1|ensembl:ENSG00000163608(gene)|ensembl:ENST00000314400(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|interpro:IPR027951|mint:Q6NW34|refseq:NP_056227.2 - - comment:"author score: 36" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lryH+qFG3/zmXWyn25dmU44prpk9606 rogid:br4UAJBanB0yJJzizE1yXlJqtwQ9606 rigid:Qhqedyyj/Y617inKhjB75dhEEmE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O75607 uniprotkb:Q9H6Y2 intact:EBI-721544|uniprotkb:Q9UNY6|intact:EBI-28974425|ensembl:ENSP00000359128 intact:EBI-5280144|uniprotkb:Q9NXK4|ensembl:ENSP00000351100 psi-mi:npm3_human(display_long)|uniprotkb:NPM3(gene name)|psi-mi:NPM3(display_short) psi-mi:wdr55_human(display_long)|uniprotkb:WDR55(gene name)|psi-mi:WDR55(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25481968|imex:IM-26985-415 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_008924.1|ensembl:ENSP00000359128|ensembl:ENSG00000107833(gene)|ensembl:ENST00000370110(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0009303"(rRNA transcription)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0042393"(histone binding)|interpro:IPR004301(Nucleoplasmin)|interpro:IPR024057|interpro:IPR036824|mint:O75607 refseq:NP_060176.2|refseq:XP_005268526.1|interpro:IPR017422(WD repeat protein 55)|interpro:IPR019775|interpro:IPR024977|interpro:IPR036322|mint:Q9H6Y2|rcsb pdb:7KQQ|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|ensembl:ENSG00000120314(gene)|ensembl:ENST00000358337(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus) - - comment:"author score: 48" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lryH+qFG3/zmXWyn25dmU44prpk9606 rogid:bAd2buaMSAqVqEt4vIB11NSh+z09606 rigid:Qhqedyyj/Y617inKhjB75dhEEmE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NFH4 uniprotkb:Q13242 intact:EBI-2563158|ensembl:ENSP00000251074|ensembl:ENSP00000448054|uniprotkb:Q9H644 intact:EBI-2949710|ensembl:ENSP00000229390|uniprotkb:Q52LD1 psi-mi:nup37_human(display_long)|uniprotkb:Nup107-160 subcomplex subunit Nup37(gene name synonym)|uniprotkb:NUP37(gene name)|psi-mi:NUP37(display_short) psi-mi:srsf9_human(display_long)|uniprotkb:SRSF9(gene name)|psi-mi:SRSF9(display_short)|uniprotkb:SFRS9(gene name synonym)|uniprotkb:SRP30C(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SRp30C(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482031|imex:IM-26985-417 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_076962.2|ensembl:ENSG00000075188(gene)|ensembl:ENST00000251074(transcript)|ensembl:ENST00000552283(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0015031"(protein transport)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037626|mint:Q8NFH4|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025 go:"GO:0006397"(mRNA processing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043279"(response to alkaloid)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|go:"GO:0006376"(mRNA splice site selection)|interpro:IPR034503|interpro:IPR034995|interpro:IPR035979|mint:Q13242|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|ensembl:ENSG00000111786(gene)|ensembl:ENST00000229390(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|refseq:NP_003760.1|dip:DIP-40741N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:mOkDLvRNOkSg/v6jnvOox6ZNTzo9606 rogid:9x6TWFk1zN1YodjXBiwi/MtNJe49606 rigid:kzBznVpd7okN5YZt35IDlddR2BM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NFH4 uniprotkb:O75494 intact:EBI-2563158|ensembl:ENSP00000251074|ensembl:ENSP00000448054|uniprotkb:Q9H644 intact:EBI-353655|uniprotkb:Q5JRI3|uniprotkb:Q5JRI4|uniprotkb:A6NFM6|uniprotkb:A6NI42|uniprotkb:A6NIU7|uniprotkb:Q5JRH9|uniprotkb:Q5JRI2|uniprotkb:O60572|uniprotkb:Q96G09|uniprotkb:Q96P17|uniprotkb:Q5JRI0|intact:EBI-11103259|ensembl:ENSP00000420195|uniprotkb:B4DJP9 psi-mi:nup37_human(display_long)|uniprotkb:Nup107-160 subcomplex subunit Nup37(gene name synonym)|uniprotkb:NUP37(gene name)|psi-mi:NUP37(display_short) psi-mi:srs10_human(display_long)|uniprotkb:FUSIP1(gene name synonym)|uniprotkb:TASR(gene name synonym)|uniprotkb:FUS-interacting serine-arginine-rich protein 1(gene name synonym)|uniprotkb:FUSIP2(gene name synonym)|uniprotkb:TLS-associated protein with Ser-Arg repeats(gene name synonym)|uniprotkb:TLS-associated serine-arginine protein(gene name synonym)|uniprotkb:40 kDa SR-repressor protein(gene name synonym)|uniprotkb:SRSF10(gene name)|psi-mi:SRSF10(display_short)|uniprotkb:Splicing factor SRp38(gene name synonym)|uniprotkb:SFRS13A(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 13A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482031|imex:IM-26985-417 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_076962.2|ensembl:ENSG00000075188(gene)|ensembl:ENST00000251074(transcript)|ensembl:ENST00000552283(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0015031"(protein transport)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037626|mint:Q8NFH4|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025 refseq:NP_001177936.1|refseq:NP_001177934.1|refseq:NP_001177935.1|refseq:NP_006616.1|refseq:NP_473357.1|ensembl:ENSG00000188529(gene)|ensembl:ENST00000492112(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0016482"(cytosolic transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0050733"(RS domain binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034476|interpro:IPR035979|mint:O75494|reactome:R-HSA-72163|refseq:NP_001177938.1 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:mOkDLvRNOkSg/v6jnvOox6ZNTzo9606 rogid:abrRZLYWl3wlG2rHzVZMgej5EWk9606 rigid:kzBznVpd7okN5YZt35IDlddR2BM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NFH4 uniprotkb:Q86U42 intact:EBI-2563158|ensembl:ENSP00000251074|ensembl:ENSP00000448054|uniprotkb:Q9H644 intact:EBI-1226435|uniprotkb:O43484|uniprotkb:D3DS49|ensembl:ENSP00000216727 psi-mi:nup37_human(display_long)|uniprotkb:Nup107-160 subcomplex subunit Nup37(gene name synonym)|uniprotkb:NUP37(gene name)|psi-mi:NUP37(display_short) psi-mi:pabp2_human(display_long)|uniprotkb:PABPN1(gene name)|psi-mi:PABPN1(display_short)|uniprotkb:PAB2(gene name synonym)|uniprotkb:PABP2(gene name synonym)|uniprotkb:"Poly(A)-binding protein II"(gene name synonym)|uniprotkb:Polyadenylate-binding nuclear protein 1(gene name synonym)|uniprotkb:"Nuclear poly(A)-binding protein 1"(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482031|imex:IM-26985-417 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_076962.2|ensembl:ENSG00000075188(gene)|ensembl:ENST00000251074(transcript)|ensembl:ENST00000552283(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0015031"(protein transport)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037626|mint:Q8NFH4|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025 refseq:NP_004634.1|dip:DIP-37968N|go:"GO:0000165"(MAPK cascade)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006396"(RNA processing)|go:"GO:0006397"(mRNA processing)|ensembl:ENSG00000100836(gene)|ensembl:ENST00000216727(transcript)|go:"GO:0006936"(muscle contraction)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1904247"(positive regulation of polynucleotide adenylyltransferase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034911|interpro:IPR035979|mint:Q86U42|rcsb pdb:3B4D|rcsb pdb:3B4M|rcsb pdb:3UCG|reactome:R-HSA-168315|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|go:"GO:0070063"(RNA polymerase binding) - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:mOkDLvRNOkSg/v6jnvOox6ZNTzo9606 rogid:NxWuFTvVqshfu+ZIsZMIZEdSk2k9606 rigid:kzBznVpd7okN5YZt35IDlddR2BM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NFH4 uniprotkb:P62987 intact:EBI-2563158|ensembl:ENSP00000251074|ensembl:ENSP00000448054|uniprotkb:Q9H644 intact:EBI-357304|ensembl:ENSP00000388107|ensembl:ENSP00000396910|ensembl:ENSP00000470419|ensembl:ENSP00000470507|ensembl:ENSP00000471062|ensembl:ENSP00000471464|ensembl:ENSP00000471622|ensembl:ENSP00000472264|ensembl:ENSP00000472545|ensembl:ENSP00000473048|uniprotkb:P14793|uniprotkb:Q9BX98|uniprotkb:Q9UPK7|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62988|uniprotkb:Q29120|uniprotkb:Q6LBL4|uniprotkb:Q6LDU5|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9BWD6|uniprotkb:Q9UEF2|uniprotkb:Q9UEG1|uniprotkb:Q9UEK8 psi-mi:nup37_human(display_long)|uniprotkb:Nup107-160 subcomplex subunit Nup37(gene name synonym)|uniprotkb:NUP37(gene name)|psi-mi:NUP37(display_short) psi-mi:rl40_human(display_long)|uniprotkb:UBA52(gene name)|psi-mi:UBA52(display_short)|uniprotkb:UBCEP2(gene name synonym)|uniprotkb:CEP52(gene name synonym)|uniprotkb:Ubiquitin A-52 residue ribosomal protein fusion product 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482031|imex:IM-26985-417 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_076962.2|ensembl:ENSG00000075188(gene)|ensembl:ENST00000251074(transcript)|ensembl:ENST00000552283(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0015031"(protein transport)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037626|mint:Q8NFH4|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025 ensembl:ENSG00000221983(gene)|ensembl:ENST00000430157(transcript)|ensembl:ENST00000442744(transcript)|ensembl:ENST00000595158(transcript)|rcsb pdb:2MBH|rcsb pdb:2MJB|rcsb pdb:2MUR|ensembl:ENST00000595683(transcript)|ensembl:ENST00000596273(transcript)|rcsb pdb:2N3U|rcsb pdb:2N3V|rcsb pdb:2N3W|rcsb pdb:2NBD|ensembl:ENST00000596304(transcript)|rcsb pdb:2NBE|rcsb pdb:2RSU|rcsb pdb:4HJK|ensembl:ENST00000597451(transcript)|ensembl:ENST00000598780(transcript)|rcsb pdb:4JIO|rcsb pdb:4P4H|rcsb pdb:4PIG|ensembl:ENST00000599551(transcript)|ensembl:ENST00000599595(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|rcsb pdb:4PIH|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017085"(response to insecticide)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000626(Ubiquitin)|interpro:IPR001975(Ribosomal protein L40e)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038587|mint:P62987|rcsb pdb:2LJ5|rcsb pdb:4PIJ|rcsb pdb:4RF0|rcsb pdb:4S1Z|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:4XKL|rcsb pdb:5AJ0|rcsb pdb:5GO7|rcsb pdb:5GO8|rcsb pdb:5GOB|rcsb pdb:5GOC|rcsb pdb:5GOD|rcsb pdb:5GOG|rcsb pdb:5GOH|rcsb pdb:5GOI|rcsb pdb:5GOJ|rcsb pdb:5GOK|rcsb pdb:5HPK|rcsb pdb:5HPL|rcsb pdb:5HPS|rcsb pdb:5HPT|rcsb pdb:5J26|rcsb pdb:5J8P|rcsb pdb:5JBV|rcsb pdb:5JBY|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:4RF1|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7AY1|rcsb pdb:7BHP|rcsb pdb:7M3Q|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|rcsb pdb:6Z6N|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|reactome:R-HSA-1253288|reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-162588|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-1799339|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|reactome:R-HSA-192823|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-211733|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2173788|reactome:R-HSA-2173791|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2408557|reactome:R-HSA-2467813|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-168928|reactome:R-HSA-174048|reactome:R-HSA-349425|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6791226|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8863795|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-69231|reactome:R-HSA-8951664|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9633012|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9683683|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-975163|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-977225|reactome:R-HSA-983168|refseq:NP_001029102.1|refseq:NP_003324.1|refseq:NP_001307947.1|refseq:NP_001307948.1|refseq:NP_001307949.1|refseq:NP_001307946.1 - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:mOkDLvRNOkSg/v6jnvOox6ZNTzo9606 rogid:x9O/Pbww4D28M1+hIj+p0xrUXgU9606 rigid:kzBznVpd7okN5YZt35IDlddR2BM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NFH4 uniprotkb:Q8WYP5 intact:EBI-2563158|ensembl:ENSP00000251074|ensembl:ENSP00000448054|uniprotkb:Q9H644 intact:EBI-396018|uniprotkb:Q7Z4E3|uniprotkb:Q8IZA4|uniprotkb:Q96EH9|uniprotkb:Q9Y4Q6|uniprotkb:A6NGM0|uniprotkb:A8MSG9|uniprotkb:A8MZ86|ensembl:ENSP00000497061 psi-mi:nup37_human(display_long)|uniprotkb:Nup107-160 subcomplex subunit Nup37(gene name synonym)|uniprotkb:NUP37(gene name)|psi-mi:NUP37(display_short) psi-mi:elys_human(display_long)|uniprotkb:Protein MEL-28(gene name synonym)|uniprotkb:Putative AT-hook-containing transcription factor 1(gene name synonym)|uniprotkb:AHCTF1(gene name)|psi-mi:AHCTF1(display_short)|uniprotkb:Embryonic large molecule derived from yolk sac(gene name synonym)|uniprotkb:ELYS(gene name synonym)|uniprotkb:TMBS62(gene name synonym)|uniprotkb:MSTP108(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482031|imex:IM-26985-417 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_076962.2|ensembl:ENSG00000075188(gene)|ensembl:ENST00000251074(transcript)|ensembl:ENST00000552283(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0015031"(protein transport)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037626|mint:Q8NFH4|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025 refseq:NP_056261.4|refseq:XP_006711821.1|refseq:NP_001310271.1|ensembl:ENSG00000153207(gene)|ensembl:ENST00000648844(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0015031"(protein transport)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR025151|interpro:IPR032040|mint:Q8WYP5|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9615933|reactome:R-HSA-9648025 - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:mOkDLvRNOkSg/v6jnvOox6ZNTzo9606 rogid:ydOhjwcpt7Vl1X/urbAgH7EQrtE9606 rigid:kzBznVpd7okN5YZt35IDlddR2BM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NFH4 uniprotkb:Q8ND56 intact:EBI-2563158|ensembl:ENSP00000251074|ensembl:ENSP00000448054|uniprotkb:Q9H644 intact:EBI-1384320|uniprotkb:Q76LX7|uniprotkb:Q96AR3|uniprotkb:Q96K73|uniprotkb:Q96SN5|uniprotkb:Q9UFR3|intact:EBI-2563702|uniprotkb:B4DTG6|ensembl:ENSP00000413964|ensembl:ENSP00000459843 psi-mi:nup37_human(display_long)|uniprotkb:Nup107-160 subcomplex subunit Nup37(gene name synonym)|uniprotkb:NUP37(gene name)|psi-mi:NUP37(display_short) psi-mi:ls14a_human(display_long)|uniprotkb:C19orf13(gene name synonym)|uniprotkb:FAM61A(gene name synonym)|uniprotkb:Protein SCD6 homolog(gene name synonym)|uniprotkb:Protein FAM61A(gene name synonym)|uniprotkb:Putative alpha-synuclein-binding protein(gene name synonym)|uniprotkb:LSM14A(gene name)|psi-mi:LSM14A(display_short)|uniprotkb:RAP55(gene name synonym)|uniprotkb:RAP55A(gene name synonym)|uniprotkb:RNA-associated protein 55A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482031|imex:IM-26985-417 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_076962.2|ensembl:ENSG00000075188(gene)|ensembl:ENST00000251074(transcript)|ensembl:ENST00000552283(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0015031"(protein transport)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037626|mint:Q8NFH4|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025 refseq:NP_001107565.1|refseq:NP_056393.2|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR019050|interpro:IPR025609|interpro:IPR025761|interpro:IPR025762|interpro:IPR025768|mint:Q8ND56|rcsb pdb:6F9W|ensembl:ENSG00000257103(gene)|ensembl:ENSG00000262860(gene)|ensembl:ENST00000433627(transcript)|ensembl:ENST00000570462(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway) - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:mOkDLvRNOkSg/v6jnvOox6ZNTzo9606 rogid:YW/zx4XyhcZZr3WCZIr1OVpyakA9606 rigid:kzBznVpd7okN5YZt35IDlddR2BM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NFH4 uniprotkb:Q8NFH3 intact:EBI-2563158|ensembl:ENSP00000251074|ensembl:ENSP00000448054|uniprotkb:Q9H644 intact:EBI-1059321|ensembl:ENSP00000342262|uniprotkb:B4E2F0|uniprotkb:Q9H8S0|intact:EBI-2563163 psi-mi:nup37_human(display_long)|uniprotkb:Nup107-160 subcomplex subunit Nup37(gene name synonym)|uniprotkb:NUP37(gene name)|psi-mi:NUP37(display_short) psi-mi:nup43_human(display_long)|uniprotkb:NUP43(gene name)|psi-mi:NUP43(display_short)|uniprotkb:Nup107-160 subcomplex subunit Nup43(gene name synonym)|uniprotkb:p42(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482031|imex:IM-26985-417 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_076962.2|ensembl:ENSG00000075188(gene)|ensembl:ENST00000251074(transcript)|ensembl:ENST00000552283(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0015031"(protein transport)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037626|mint:Q8NFH4|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025 go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0015031"(protein transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR036322|mint:Q8NFH3|rcsb pdb:4I79|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|go:"GO:0000776"(kinetochore)|ensembl:ENSG00000120253(gene)|ensembl:ENST00000340413(transcript)|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-4085377|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-159227|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|refseq:NP_942590.1 - - comment:"author score: 29" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:mOkDLvRNOkSg/v6jnvOox6ZNTzo9606 rogid:9dnsBBdsFhkUGq330asCg5EKM2w9606 rigid:kzBznVpd7okN5YZt35IDlddR2BM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NFH4 uniprotkb:Q8WUM0 intact:EBI-2563158|ensembl:ENSP00000251074|ensembl:ENSP00000448054|uniprotkb:Q9H644 intact:EBI-295695|uniprotkb:Q5T8N0|uniprotkb:Q9H9W2|uniprotkb:Q9NV71|uniprotkb:Q9NVC4|uniprotkb:B2RAZ8|ensembl:ENSP00000261396 psi-mi:nup37_human(display_long)|uniprotkb:Nup107-160 subcomplex subunit Nup37(gene name synonym)|uniprotkb:NUP37(gene name)|psi-mi:NUP37(display_short) psi-mi:nu133_human(display_long)|uniprotkb:NUP133(gene name)|psi-mi:NUP133(display_short)|uniprotkb:Nucleoporin Nup133(gene name synonym)|uniprotkb:133 kDa nucleoporin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482031|imex:IM-26985-417 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_076962.2|ensembl:ENSG00000075188(gene)|ensembl:ENST00000251074(transcript)|ensembl:ENST00000552283(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0015031"(protein transport)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037626|mint:Q8NFH4|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025 refseq:NP_060700.2|ensembl:ENSG00000069248(gene)|ensembl:ENST00000261396(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0021915"(neural tube development)|go:"GO:0022008"(neurogenesis)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0061053"(somite development)|go:"GO:0072006"(nephron development)|interpro:IPR007187(Nucleoporin, Nup133-like, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037624|mint:Q8WUM0|rcsb pdb:1XKS|rcsb pdb:3CQC|rcsb pdb:3CQG|rcsb pdb:3I4R|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025 - - comment:"author score: 33" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:mOkDLvRNOkSg/v6jnvOox6ZNTzo9606 rogid:J89Ja9KNryxKNUd9rqNbi8EC09g9606 rigid:kzBznVpd7okN5YZt35IDlddR2BM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NFH4 uniprotkb:Q12769 intact:EBI-2563158|ensembl:ENSP00000251074|ensembl:ENSP00000448054|uniprotkb:Q9H644 intact:EBI-295715|uniprotkb:Q96GB3|uniprotkb:Q9H660|uniprotkb:B4DYE8|uniprotkb:B4E2J9|uniprotkb:Q08AD3|uniprotkb:Q7Z5X6|intact:EBI-2563140|ensembl:ENSP00000367721 psi-mi:nup37_human(display_long)|uniprotkb:Nup107-160 subcomplex subunit Nup37(gene name synonym)|uniprotkb:NUP37(gene name)|psi-mi:NUP37(display_short) psi-mi:nu160_human(display_long)|uniprotkb:NUP160(gene name)|psi-mi:NUP160(display_short)|uniprotkb:KIAA0197(gene name synonym)|uniprotkb:NUP120(gene name synonym)|uniprotkb:Nucleoporin Nup160(gene name synonym)|uniprotkb:160 kDa nucleoporin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482031|imex:IM-26985-417 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_076962.2|ensembl:ENSG00000075188(gene)|ensembl:ENST00000251074(transcript)|ensembl:ENST00000552283(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0015031"(protein transport)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037626|mint:Q8NFH4|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025 refseq:NP_056046.1|refseq:NP_001305328.1|dip:DIP-31262N|ensembl:ENSG00000030066(gene)|ensembl:ENST00000378460(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0015031"(protein transport)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0072006"(nephron development)|interpro:IPR021717|mint:Q12769|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025 - - comment:"author score: 36" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:mOkDLvRNOkSg/v6jnvOox6ZNTzo9606 rogid:15tRpv4+wvw31oJPxM42NxWdRUc9606 rigid:kzBznVpd7okN5YZt35IDlddR2BM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NFH4 uniprotkb:P55735 intact:EBI-2563158|ensembl:ENSP00000251074|ensembl:ENSP00000448054|uniprotkb:Q9H644 intact:EBI-1046596|ensembl:ENSP00000312122|uniprotkb:Q5BJF0|uniprotkb:Q9BRM6|uniprotkb:Q9BUG7|uniprotkb:A8MV37|uniprotkb:B4DXJ1 psi-mi:nup37_human(display_long)|uniprotkb:Nup107-160 subcomplex subunit Nup37(gene name synonym)|uniprotkb:NUP37(gene name)|psi-mi:NUP37(display_short) psi-mi:sec13_human(display_long)|uniprotkb:SEC13(gene name)|psi-mi:SEC13(display_short)|uniprotkb:D3S1231E(gene name synonym)|uniprotkb:SEC13L1(gene name synonym)|uniprotkb:SEC13R(gene name synonym)|uniprotkb:SEC13-related protein(gene name synonym)|uniprotkb:SEC13-like protein 1(gene name synonym)|uniprotkb:GATOR complex protein SEC13(gene name synonym)|uniprotkb:SEC13A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482031|imex:IM-26985-417 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_076962.2|ensembl:ENSG00000075188(gene)|ensembl:ENST00000251074(transcript)|ensembl:ENST00000552283(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0015031"(protein transport)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037626|mint:Q8NFH4|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025 go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0005829"(cytosol)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051028"(mRNA transport)|go:"GO:0061700"(GATOR2 complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037363|interpro:IPR037596|mint:P55735|rcsb pdb:3BG0|rcsb pdb:3BG1|go:"GO:0006886"(intracellular protein transport)|rcsb pdb:5A9Q|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|reactome:R-HSA-1169408|reactome:R-HSA-141444|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0031080"(nuclear pore outer ring)|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-168333|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9639288|reactome:R-HSA-9648025|reactome:R-HSA-983170|ensembl:ENSG00000157020(gene)|ensembl:ENST00000350697(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|refseq:NP_001129704.1|refseq:NP_899195.1|refseq:XP_016862508.1|refseq:NP_001129498.1|refseq:NP_109598.2|refseq:XP_005265436.1|dip:DIP-39091N - - comment:"author score: 37" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:mOkDLvRNOkSg/v6jnvOox6ZNTzo9606 rogid:vaNNziH0RNn0+mHITi5+FST0E0s9606 rigid:kzBznVpd7okN5YZt35IDlddR2BM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NFH4 uniprotkb:P57740 intact:EBI-2563158|ensembl:ENSP00000251074|ensembl:ENSP00000448054|uniprotkb:Q9H644 intact:EBI-295687|uniprotkb:B4DZ67|uniprotkb:Q6PJE1|intact:EBI-10966404|ensembl:ENSP00000229179 psi-mi:nup37_human(display_long)|uniprotkb:Nup107-160 subcomplex subunit Nup37(gene name synonym)|uniprotkb:NUP37(gene name)|psi-mi:NUP37(display_short) psi-mi:nu107_human(display_long)|uniprotkb:NUP107(gene name)|psi-mi:NUP107(display_short)|uniprotkb:Nucleoporin Nup107(gene name synonym)|uniprotkb:107 kDa nucleoporin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482031|imex:IM-26985-417 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_076962.2|ensembl:ENSG00000075188(gene)|ensembl:ENST00000251074(transcript)|ensembl:ENST00000552283(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0015031"(protein transport)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037626|mint:Q8NFH4|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025 refseq:NP_065134.1|refseq:NP_001317121.1|ensembl:ENSG00000111581(gene)|ensembl:ENST00000229179(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008585"(female gonad development)|go:"GO:0016020"(membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0072006"(nephron development)|interpro:IPR007252(Nuclear pore protein 84/107)|mint:P57740|rcsb pdb:3CQC|rcsb pdb:3CQG|rcsb pdb:3I4R|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025 - - comment:"author score: 40" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:mOkDLvRNOkSg/v6jnvOox6ZNTzo9606 rogid:76eAOFdL5JLBp0giaH8nhc3BMEI9606 rigid:kzBznVpd7okN5YZt35IDlddR2BM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NFH4 uniprotkb:Q9BW27 intact:EBI-2563158|ensembl:ENSP00000251074|ensembl:ENSP00000448054|uniprotkb:Q9H644 intact:EBI-716392|intact:EBI-2563151|uniprotkb:Q9H9U1|uniprotkb:Q8NDI4|uniprotkb:B4DMQ3|uniprotkb:B4DPW1|ensembl:ENSP00000245544 psi-mi:nup37_human(display_long)|uniprotkb:Nup107-160 subcomplex subunit Nup37(gene name synonym)|uniprotkb:NUP37(gene name)|psi-mi:NUP37(display_short) psi-mi:nup85_human(display_long)|uniprotkb:PCNT1(gene name synonym)|uniprotkb:Nucleoporin Nup85(gene name synonym)|uniprotkb:85 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin Nup75(gene name synonym)|uniprotkb:Pericentrin-1(gene name synonym)|uniprotkb:FROUNT(gene name synonym)|uniprotkb:NUP85(gene name)|psi-mi:NUP85(display_short)|uniprotkb:NUP75(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482031|imex:IM-26985-417 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_076962.2|ensembl:ENSG00000075188(gene)|ensembl:ENST00000251074(transcript)|ensembl:ENST00000552283(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0015031"(protein transport)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037626|mint:Q8NFH4|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025 refseq:NP_079120.1|refseq:NP_001290205.1|ensembl:ENSG00000125450(gene)|ensembl:ENST00000245544(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0016020"(membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0072006"(nephron development)|interpro:IPR011502(Nucleoporin, Nup85-like)|mint:Q9BW27|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025 - - comment:"author score: 40" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:mOkDLvRNOkSg/v6jnvOox6ZNTzo9606 rogid:MWeo3e2aXVKhP1gFV8ZZrgyFSeI9606 rigid:kzBznVpd7okN5YZt35IDlddR2BM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NFH4 uniprotkb:P52948 intact:EBI-2563158|ensembl:ENSP00000251074|ensembl:ENSP00000448054|uniprotkb:Q9H644 intact:EBI-295727|uniprotkb:Q8IUT2|uniprotkb:Q8WYB0|uniprotkb:Q96E54|uniprotkb:Q9H3Q4|uniprotkb:Q9NT02|uniprotkb:Q9UF57|uniprotkb:Q9UHX0|uniprotkb:Q9Y6J4|uniprotkb:Q9Y6J5|ensembl:ENSP00000352091 psi-mi:nup37_human(display_long)|uniprotkb:Nup107-160 subcomplex subunit Nup37(gene name synonym)|uniprotkb:NUP37(gene name)|psi-mi:NUP37(display_short) psi-mi:nup98_human(display_long)|uniprotkb:NUP98(gene name)|psi-mi:NUP98(display_short)|uniprotkb:ADAR2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482031|imex:IM-26985-417 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_076962.2|ensembl:ENSG00000075188(gene)|ensembl:ENST00000251074(transcript)|ensembl:ENST00000552283(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0015031"(protein transport)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037626|mint:Q8NFH4|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025 refseq:NP_005378.4|refseq:NP_057404.2|refseq:NP_624357.1|refseq:NP_624358.2|ensembl:ENST00000324932|ensembl:ENSP00000316032|ensembl:ENST00000355260|ensembl:ENSP00000347404|ensembl:ENSP00000352091|ensembl:ENST00000397004|ensembl:ENSP00000380199|ensembl:ENST00000397007|ensembl:ENSP00000380202|dip:DIP-32484N|ensembl:ENSG00000110713(gene)|ensembl:ENST00000359171(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005215"(transporter activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR021967|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|mint:P52948|rcsb pdb:1KO6|rcsb pdb:2Q5X|rcsb pdb:2Q5Y|rcsb pdb:3MMY|rcsb pdb:4OWR|rcsb pdb:5A9Q|rcsb pdb:6BZM|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025 - - comment:"author score: 46" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:mOkDLvRNOkSg/v6jnvOox6ZNTzo9606 rogid:aW9NaKgLZti0wLEiVQogGukcWdE9606 rigid:kzBznVpd7okN5YZt35IDlddR2BM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NFH3 uniprotkb:Q96EE3 intact:EBI-1059321|ensembl:ENSP00000342262|uniprotkb:B4E2F0|uniprotkb:Q9H8S0|intact:EBI-2563163 intact:EBI-922818|uniprotkb:Q8NFU6|uniprotkb:Q96MH3|uniprotkb:Q9C069|uniprotkb:A8K5B1|ensembl:ENSP00000262124 psi-mi:nup43_human(display_long)|uniprotkb:NUP43(gene name)|psi-mi:NUP43(display_short)|uniprotkb:Nup107-160 subcomplex subunit Nup43(gene name synonym)|uniprotkb:p42(gene name synonym) psi-mi:seh1_human(display_long)|uniprotkb:Nup107-160 subcomplex subunit SEH1(gene name synonym)|uniprotkb:SEH1L(gene name)|psi-mi:SEH1L(display_short)|uniprotkb:SEC13L(gene name synonym)|uniprotkb:SEH1(gene name synonym)|uniprotkb:SEC13-like protein(gene name synonym)|uniprotkb:GATOR complex protein SEH1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482076|imex:IM-26985-261 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0015031"(protein transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR036322|mint:Q8NFH3|rcsb pdb:4I79|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|go:"GO:0000776"(kinetochore)|ensembl:ENSG00000120253(gene)|ensembl:ENST00000340413(transcript)|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-4085377|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-159227|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|refseq:NP_942590.1 refseq:NP_001013455.1|refseq:NP_112493.2|ensembl:ENSP00000262124|ensembl:ENST00000399892|ensembl:ENSP00000382779|ensembl:ENSG00000085415(gene)|ensembl:ENST00000262124(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0015031"(protein transport)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034629"|go:"GO:0035859"(Seh1-associated complex)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0061700"(GATOR2 complex)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|interpro:IPR037363|interpro:IPR037597|mint:Q96EE3|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9639288|reactome:R-HSA-9648025 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:9dnsBBdsFhkUGq330asCg5EKM2w9606 rogid:I/aUTa3zTawK6QwtkrUkO8B51W49606 rigid:llX2Xcz5dXmArz7g5jYZp6RFXpc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NFH3 uniprotkb:P37802 intact:EBI-1059321|ensembl:ENSP00000342262|uniprotkb:B4E2F0|uniprotkb:Q9H8S0|intact:EBI-2563163 intact:EBI-1056740|intact:EBI-2825986|uniprotkb:Q5JRQ6|uniprotkb:Q5JRQ7|uniprotkb:Q9BUH5|uniprotkb:Q9H4P0|uniprotkb:Q6FGI1|uniprotkb:E9KL39|ensembl:ENSP00000357075|ensembl:ENSP00000357077 psi-mi:nup43_human(display_long)|uniprotkb:NUP43(gene name)|psi-mi:NUP43(display_short)|uniprotkb:Nup107-160 subcomplex subunit Nup43(gene name synonym)|uniprotkb:p42(gene name synonym) psi-mi:tagl2_human(display_long)|uniprotkb:TAGLN2(gene name)|psi-mi:TAGLN2(display_short)|uniprotkb:KIAA0120(gene name synonym)|uniprotkb:SM22-alpha homolog(gene name synonym)|uniprotkb:CDABP0035(orf name)|uniprotkb:Epididymis tissue protein Li 7e(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482076|imex:IM-26985-261 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0015031"(protein transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR036322|mint:Q8NFH3|rcsb pdb:4I79|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|go:"GO:0000776"(kinetochore)|ensembl:ENSG00000120253(gene)|ensembl:ENST00000340413(transcript)|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-4085377|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-159227|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|refseq:NP_942590.1 refseq:NP_003555.1|refseq:NP_001264152.1|refseq:NP_001264153.1|ensembl:ENSG00000158710(gene)|ensembl:ENST00000320307(transcript)|ensembl:ENST00000368097(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031982"(vesicle)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000557(Calponin repeat)|interpro:IPR001061("Transgelin (SM22-alpha)")|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR036872|mint:P37802|rcsb pdb:1WYM|reactome:R-HSA-114608 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:9dnsBBdsFhkUGq330asCg5EKM2w9606 rogid:JxbMK5SbZWQd+XA9iYc/xuNaVQc9606 rigid:llX2Xcz5dXmArz7g5jYZp6RFXpc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NFH3 uniprotkb:P57721 intact:EBI-1059321|ensembl:ENSP00000342262|uniprotkb:B4E2F0|uniprotkb:Q9H8S0|intact:EBI-2563163 intact:EBI-954627|uniprotkb:Q8N9K6|uniprotkb:Q96EP6|uniprotkb:A8MPS2|uniprotkb:A8MQ26|uniprotkb:B7WNN9|uniprotkb:B7WPC1|ensembl:ENSP00000383168|ensembl:ENSP00000505796|intact:EBI-2555264 psi-mi:nup43_human(display_long)|uniprotkb:NUP43(gene name)|psi-mi:NUP43(display_short)|uniprotkb:Nup107-160 subcomplex subunit Nup43(gene name synonym)|uniprotkb:p42(gene name synonym) psi-mi:pcbp3_human(display_long)|uniprotkb:PCBP3-overlapping transcript(gene name synonym)|uniprotkb:PCBP3-overlapping transcript 1(gene name synonym)|uniprotkb:PCBP3OT(gene name synonym)|uniprotkb:PCBP3(gene name)|psi-mi:PCBP3(display_short)|uniprotkb:Alpha-CP3(gene name synonym)|uniprotkb:PCBP3-OT1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482076|imex:IM-26985-261 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0015031"(protein transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR036322|mint:Q8NFH3|rcsb pdb:4I79|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|go:"GO:0000776"(kinetochore)|ensembl:ENSG00000120253(gene)|ensembl:ENST00000340413(transcript)|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-4085377|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-159227|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|refseq:NP_942590.1 ensembl:ENSG00000183570(gene)|ensembl:ENST00000400314(transcript)|ensembl:ENST00000681687(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016071"(mRNA metabolic process)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:P57721|refseq:NP_001123613.1|refseq:NP_065389.2|refseq:NP_001335167.1|refseq:NP_001335171.1|refseq:NP_001335173.1 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:9dnsBBdsFhkUGq330asCg5EKM2w9606 rogid:FM/z2+gksm+t2UY+BhMIl/myjqk9606 rigid:llX2Xcz5dXmArz7g5jYZp6RFXpc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NFH3 uniprotkb:P55735 intact:EBI-1059321|ensembl:ENSP00000342262|uniprotkb:B4E2F0|uniprotkb:Q9H8S0|intact:EBI-2563163 intact:EBI-1046596|ensembl:ENSP00000312122|uniprotkb:Q5BJF0|uniprotkb:Q9BRM6|uniprotkb:Q9BUG7|uniprotkb:A8MV37|uniprotkb:B4DXJ1 psi-mi:nup43_human(display_long)|uniprotkb:NUP43(gene name)|psi-mi:NUP43(display_short)|uniprotkb:Nup107-160 subcomplex subunit Nup43(gene name synonym)|uniprotkb:p42(gene name synonym) psi-mi:sec13_human(display_long)|uniprotkb:SEC13(gene name)|psi-mi:SEC13(display_short)|uniprotkb:D3S1231E(gene name synonym)|uniprotkb:SEC13L1(gene name synonym)|uniprotkb:SEC13R(gene name synonym)|uniprotkb:SEC13-related protein(gene name synonym)|uniprotkb:SEC13-like protein 1(gene name synonym)|uniprotkb:GATOR complex protein SEC13(gene name synonym)|uniprotkb:SEC13A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482076|imex:IM-26985-261 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0015031"(protein transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR036322|mint:Q8NFH3|rcsb pdb:4I79|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|go:"GO:0000776"(kinetochore)|ensembl:ENSG00000120253(gene)|ensembl:ENST00000340413(transcript)|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-4085377|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-159227|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|refseq:NP_942590.1 go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0032527"(protein exit from endoplasmic reticulum)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0005829"(cytosol)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051028"(mRNA transport)|go:"GO:0061700"(GATOR2 complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:1904263"(positive regulation of TORC1 signaling)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR037363|interpro:IPR037596|mint:P55735|rcsb pdb:3BG0|rcsb pdb:3BG1|go:"GO:0006886"(intracellular protein transport)|rcsb pdb:5A9Q|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|reactome:R-HSA-1169408|reactome:R-HSA-141444|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0031080"(nuclear pore outer ring)|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-168333|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9639288|reactome:R-HSA-9648025|reactome:R-HSA-983170|ensembl:ENSG00000157020(gene)|ensembl:ENST00000350697(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|refseq:NP_001129704.1|refseq:NP_899195.1|refseq:XP_016862508.1|refseq:NP_001129498.1|refseq:NP_109598.2|refseq:XP_005265436.1|dip:DIP-39091N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:9dnsBBdsFhkUGq330asCg5EKM2w9606 rogid:vaNNziH0RNn0+mHITi5+FST0E0s9606 rigid:llX2Xcz5dXmArz7g5jYZp6RFXpc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NFH3 uniprotkb:Q9BW27 intact:EBI-1059321|ensembl:ENSP00000342262|uniprotkb:B4E2F0|uniprotkb:Q9H8S0|intact:EBI-2563163 intact:EBI-716392|intact:EBI-2563151|uniprotkb:Q9H9U1|uniprotkb:Q8NDI4|uniprotkb:B4DMQ3|uniprotkb:B4DPW1|ensembl:ENSP00000245544 psi-mi:nup43_human(display_long)|uniprotkb:NUP43(gene name)|psi-mi:NUP43(display_short)|uniprotkb:Nup107-160 subcomplex subunit Nup43(gene name synonym)|uniprotkb:p42(gene name synonym) psi-mi:nup85_human(display_long)|uniprotkb:PCNT1(gene name synonym)|uniprotkb:Nucleoporin Nup85(gene name synonym)|uniprotkb:85 kDa nucleoporin(gene name synonym)|uniprotkb:Nucleoporin Nup75(gene name synonym)|uniprotkb:Pericentrin-1(gene name synonym)|uniprotkb:FROUNT(gene name synonym)|uniprotkb:NUP85(gene name)|psi-mi:NUP85(display_short)|uniprotkb:NUP75(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482076|imex:IM-26985-261 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0015031"(protein transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR036322|mint:Q8NFH3|rcsb pdb:4I79|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|go:"GO:0000776"(kinetochore)|ensembl:ENSG00000120253(gene)|ensembl:ENST00000340413(transcript)|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-4085377|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-159227|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|refseq:NP_942590.1 refseq:NP_079120.1|refseq:NP_001290205.1|ensembl:ENSG00000125450(gene)|ensembl:ENST00000245544(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0016020"(membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048246"(macrophage chemotaxis)|go:"GO:0072006"(nephron development)|interpro:IPR011502(Nucleoporin, Nup85-like)|mint:Q9BW27|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:9dnsBBdsFhkUGq330asCg5EKM2w9606 rogid:MWeo3e2aXVKhP1gFV8ZZrgyFSeI9606 rigid:llX2Xcz5dXmArz7g5jYZp6RFXpc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NFH3 uniprotkb:Q8WUM0 intact:EBI-1059321|ensembl:ENSP00000342262|uniprotkb:B4E2F0|uniprotkb:Q9H8S0|intact:EBI-2563163 intact:EBI-295695|uniprotkb:Q5T8N0|uniprotkb:Q9H9W2|uniprotkb:Q9NV71|uniprotkb:Q9NVC4|uniprotkb:B2RAZ8|ensembl:ENSP00000261396 psi-mi:nup43_human(display_long)|uniprotkb:NUP43(gene name)|psi-mi:NUP43(display_short)|uniprotkb:Nup107-160 subcomplex subunit Nup43(gene name synonym)|uniprotkb:p42(gene name synonym) psi-mi:nu133_human(display_long)|uniprotkb:NUP133(gene name)|psi-mi:NUP133(display_short)|uniprotkb:Nucleoporin Nup133(gene name synonym)|uniprotkb:133 kDa nucleoporin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482076|imex:IM-26985-261 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0015031"(protein transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR036322|mint:Q8NFH3|rcsb pdb:4I79|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|go:"GO:0000776"(kinetochore)|ensembl:ENSG00000120253(gene)|ensembl:ENST00000340413(transcript)|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-4085377|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-159227|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|refseq:NP_942590.1 refseq:NP_060700.2|ensembl:ENSG00000069248(gene)|ensembl:ENST00000261396(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0016020"(membrane)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0021915"(neural tube development)|go:"GO:0022008"(neurogenesis)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0061053"(somite development)|go:"GO:0072006"(nephron development)|interpro:IPR007187(Nucleoporin, Nup133-like, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037624|mint:Q8WUM0|rcsb pdb:1XKS|rcsb pdb:3CQC|rcsb pdb:3CQG|rcsb pdb:3I4R|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025 - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:9dnsBBdsFhkUGq330asCg5EKM2w9606 rogid:J89Ja9KNryxKNUd9rqNbi8EC09g9606 rigid:llX2Xcz5dXmArz7g5jYZp6RFXpc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NFH3 uniprotkb:P57740 intact:EBI-1059321|ensembl:ENSP00000342262|uniprotkb:B4E2F0|uniprotkb:Q9H8S0|intact:EBI-2563163 intact:EBI-295687|uniprotkb:B4DZ67|uniprotkb:Q6PJE1|intact:EBI-10966404|ensembl:ENSP00000229179 psi-mi:nup43_human(display_long)|uniprotkb:NUP43(gene name)|psi-mi:NUP43(display_short)|uniprotkb:Nup107-160 subcomplex subunit Nup43(gene name synonym)|uniprotkb:p42(gene name synonym) psi-mi:nu107_human(display_long)|uniprotkb:NUP107(gene name)|psi-mi:NUP107(display_short)|uniprotkb:Nucleoporin Nup107(gene name synonym)|uniprotkb:107 kDa nucleoporin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482076|imex:IM-26985-261 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0015031"(protein transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR036322|mint:Q8NFH3|rcsb pdb:4I79|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|go:"GO:0000776"(kinetochore)|ensembl:ENSG00000120253(gene)|ensembl:ENST00000340413(transcript)|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-4085377|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-159227|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|refseq:NP_942590.1 refseq:NP_065134.1|refseq:NP_001317121.1|ensembl:ENSG00000111581(gene)|ensembl:ENST00000229179(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000973"(posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008585"(female gonad development)|go:"GO:0016020"(membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0072006"(nephron development)|interpro:IPR007252(Nuclear pore protein 84/107)|mint:P57740|rcsb pdb:3CQC|rcsb pdb:3CQG|rcsb pdb:3I4R|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025 - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:9dnsBBdsFhkUGq330asCg5EKM2w9606 rogid:76eAOFdL5JLBp0giaH8nhc3BMEI9606 rigid:llX2Xcz5dXmArz7g5jYZp6RFXpc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NFH3 uniprotkb:P52948 intact:EBI-1059321|ensembl:ENSP00000342262|uniprotkb:B4E2F0|uniprotkb:Q9H8S0|intact:EBI-2563163 intact:EBI-295727|uniprotkb:Q8IUT2|uniprotkb:Q8WYB0|uniprotkb:Q96E54|uniprotkb:Q9H3Q4|uniprotkb:Q9NT02|uniprotkb:Q9UF57|uniprotkb:Q9UHX0|uniprotkb:Q9Y6J4|uniprotkb:Q9Y6J5|ensembl:ENSP00000352091 psi-mi:nup43_human(display_long)|uniprotkb:NUP43(gene name)|psi-mi:NUP43(display_short)|uniprotkb:Nup107-160 subcomplex subunit Nup43(gene name synonym)|uniprotkb:p42(gene name synonym) psi-mi:nup98_human(display_long)|uniprotkb:NUP98(gene name)|psi-mi:NUP98(display_short)|uniprotkb:ADAR2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482076|imex:IM-26985-261 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0015031"(protein transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0051028"(mRNA transport)|go:"GO:0051301"(cell division)|interpro:IPR001680(WD40 repeat)|interpro:IPR019775|interpro:IPR036322|mint:Q8NFH3|rcsb pdb:4I79|rcsb pdb:5A9Q|reactome:R-HSA-1169408|reactome:R-HSA-141444|go:"GO:0000776"(kinetochore)|ensembl:ENSG00000120253(gene)|ensembl:ENST00000340413(transcript)|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-4085377|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-159227|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|refseq:NP_942590.1 refseq:NP_005378.4|refseq:NP_057404.2|refseq:NP_624357.1|refseq:NP_624358.2|ensembl:ENST00000324932|ensembl:ENSP00000316032|ensembl:ENST00000355260|ensembl:ENSP00000347404|ensembl:ENSP00000352091|ensembl:ENST00000397004|ensembl:ENSP00000380199|ensembl:ENST00000397007|ensembl:ENSP00000380202|dip:DIP-32484N|ensembl:ENSG00000110713(gene)|ensembl:ENST00000359171(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005215"(transporter activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006913"(nucleocytoplasmic transport)|go:"GO:0006999"(nuclear pore organization)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031080"(nuclear pore outer ring)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR007230(Peptidase S59, nucleoporin)|interpro:IPR021967|interpro:IPR036903|interpro:IPR037637|interpro:IPR037665|mint:P52948|rcsb pdb:1KO6|rcsb pdb:2Q5X|rcsb pdb:2Q5Y|rcsb pdb:3MMY|rcsb pdb:4OWR|rcsb pdb:5A9Q|rcsb pdb:6BZM|reactome:R-HSA-1169408|reactome:R-HSA-141444|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-5663220|reactome:R-HSA-6784531|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9615933|reactome:R-HSA-9648025 - - comment:"author score: 27" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:9dnsBBdsFhkUGq330asCg5EKM2w9606 rogid:aW9NaKgLZti0wLEiVQogGukcWdE9606 rigid:llX2Xcz5dXmArz7g5jYZp6RFXpc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N3A8 uniprotkb:Q06265 intact:EBI-8796778|ensembl:ENSP00000281631|ensembl:ENSP00000422217|uniprotkb:Q9H754|uniprotkb:Q3KRB7|uniprotkb:Q6DHZ1 intact:EBI-347966|ensembl:ENSP00000243498|uniprotkb:Q12883|uniprotkb:Q86Y41|uniprotkb:Q86Y48|uniprotkb:Q4W5P5 psi-mi:parp8_human(display_long)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 16(gene name synonym)|uniprotkb:PARP8(gene name)|psi-mi:PARP8(display_short)|uniprotkb:Poly [ADP-ribose] polymerase 8(gene name synonym) psi-mi:exos9_human(display_long)|uniprotkb:EXOSC9(gene name)|psi-mi:EXOSC9(display_short)|uniprotkb:PMSCL1(gene name synonym)|uniprotkb:Exosome component 9(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 1(gene name synonym)|uniprotkb:Autoantigen PM/Scl 1(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 75 kDa(gene name synonym)|uniprotkb:P75 polymyositis-scleroderma overlap syndrome-associated autoantigen(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482208|imex:IM-26985-493 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0140289"(protein mono-ADP-ribosylation)|go:"GO:1990404"(protein ADP-ribosylase activity)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|mint:Q8N3A8|reactome:R-HSA-197264|reactome:R-HSA-9683610|reactome:R-HSA-9694631|go:"GO:0070213"(protein auto-ADP-ribosylation)|ensembl:ENSG00000151883(gene)|ensembl:ENST00000281631(transcript)|ensembl:ENST00000505697(transcript)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0006471"(protein ADP-ribosylation)|refseq:XP_011541934.2|refseq:XP_011541933.1|refseq:NP_001171526.1|refseq:NP_001171527.1|refseq:NP_078891.2 go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006955"(immune response)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033100|interpro:IPR036345|mint:Q06265|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|ensembl:ENSG00000123737(gene)|ensembl:ENST00000243498(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|refseq:NP_001029366.1|refseq:NP_005024.2|dip:DIP-31286N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:40j9kPtn+p1lGYBXWsL+a6aKcyo9606 rogid:COzGZISdlfGlht1FhyxPhzbV9hY9606 rigid:d4/W5keR9MGdw9KV+jJ9C+XKR9E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N3A8 uniprotkb:P81605 intact:EBI-8796778|ensembl:ENSP00000281631|ensembl:ENSP00000422217|uniprotkb:Q9H754|uniprotkb:Q3KRB7|uniprotkb:Q6DHZ1 intact:EBI-395625|uniprotkb:P58461|uniprotkb:A5JHP2|uniprotkb:A5JHP3|uniprotkb:Q53YJ2|ensembl:ENSP00000293371 psi-mi:parp8_human(display_long)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 16(gene name synonym)|uniprotkb:PARP8(gene name)|psi-mi:PARP8(display_short)|uniprotkb:Poly [ADP-ribose] polymerase 8(gene name synonym) psi-mi:dcd_human(display_long)|uniprotkb:AIDD(gene name synonym)|uniprotkb:DSEP(gene name synonym)|uniprotkb:Preproteolysin(gene name synonym)|uniprotkb:DCD(gene name)|psi-mi:DCD(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482208|imex:IM-26985-493 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0140289"(protein mono-ADP-ribosylation)|go:"GO:1990404"(protein ADP-ribosylase activity)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|mint:Q8N3A8|reactome:R-HSA-197264|reactome:R-HSA-9683610|reactome:R-HSA-9694631|go:"GO:0070213"(protein auto-ADP-ribosylation)|ensembl:ENSG00000151883(gene)|ensembl:ENST00000281631(transcript)|ensembl:ENST00000505697(transcript)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0006471"(protein ADP-ribosylation)|refseq:XP_011541934.2|refseq:XP_011541933.1|refseq:NP_001171526.1|refseq:NP_001171527.1|refseq:NP_078891.2 refseq:NP_444513.1|refseq:NP_001287783.1|ensembl:ENSG00000161634(gene)|ensembl:ENST00000293371(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008233"(peptidase activity)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR028130|interpro:IPR043557|mint:P81605|rcsb pdb:2KSG|rcsb pdb:2NDK|rcsb pdb:2YMK|rcsb pdb:6SHK|reactome:R-HSA-6803157 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:40j9kPtn+p1lGYBXWsL+a6aKcyo9606 rogid:M8PkKVWx98nhtd79ods05mqw8Ls9606 rigid:d4/W5keR9MGdw9KV+jJ9C+XKR9E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N3A8 uniprotkb:Q15024 intact:EBI-8796778|ensembl:ENSP00000281631|ensembl:ENSP00000422217|uniprotkb:Q9H754|uniprotkb:Q3KRB7|uniprotkb:Q6DHZ1 intact:EBI-371841|uniprotkb:Q96E72|ensembl:ENSP00000265564 psi-mi:parp8_human(display_long)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 16(gene name synonym)|uniprotkb:PARP8(gene name)|psi-mi:PARP8(display_short)|uniprotkb:Poly [ADP-ribose] polymerase 8(gene name synonym) psi-mi:exos7_human(display_long)|uniprotkb:KIAA0116(gene name synonym)|uniprotkb:RRP42(gene name synonym)|uniprotkb:EXOSC7(gene name)|psi-mi:EXOSC7(display_short)|uniprotkb:Ribosomal RNA-processing protein 42(gene name synonym)|uniprotkb:Exosome component 7(gene name synonym)|uniprotkb:p8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482208|imex:IM-26985-493 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0140289"(protein mono-ADP-ribosylation)|go:"GO:1990404"(protein ADP-ribosylase activity)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|mint:Q8N3A8|reactome:R-HSA-197264|reactome:R-HSA-9683610|reactome:R-HSA-9694631|go:"GO:0070213"(protein auto-ADP-ribosylation)|ensembl:ENSG00000151883(gene)|ensembl:ENST00000281631(transcript)|ensembl:ENST00000505697(transcript)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0006471"(protein ADP-ribosylation)|refseq:XP_011541934.2|refseq:XP_011541933.1|refseq:NP_001171526.1|refseq:NP_001171527.1|refseq:NP_078891.2 refseq:NP_055819.2|ensembl:ENSG00000075914(gene)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|ensembl:ENST00000265564(transcript)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q15024|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|go:"GO:0034475"(U4 snRNA 3'-end processing)|dip:DIP-31266N - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:40j9kPtn+p1lGYBXWsL+a6aKcyo9606 rogid:gFGj7nvYM3a56Pu7vryrP+XfUxE9606 rigid:d4/W5keR9MGdw9KV+jJ9C+XKR9E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N3A8 uniprotkb:P01040 intact:EBI-8796778|ensembl:ENSP00000281631|ensembl:ENSP00000422217|uniprotkb:Q9H754|uniprotkb:Q3KRB7|uniprotkb:Q6DHZ1 intact:EBI-724303|ensembl:ENSP00000264474|uniprotkb:Q6IB90 psi-mi:parp8_human(display_long)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 16(gene name synonym)|uniprotkb:PARP8(gene name)|psi-mi:PARP8(display_short)|uniprotkb:Poly [ADP-ribose] polymerase 8(gene name synonym) psi-mi:cyta_human(display_long)|uniprotkb:Cystatin-AS(gene name synonym)|uniprotkb:Stefin-A(gene name synonym)|uniprotkb:CSTA(gene name)|psi-mi:CSTA(display_short)|uniprotkb:STF1(gene name synonym)|uniprotkb:STFA(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482208|imex:IM-26985-493 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0140289"(protein mono-ADP-ribosylation)|go:"GO:1990404"(protein ADP-ribosylase activity)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|mint:Q8N3A8|reactome:R-HSA-197264|reactome:R-HSA-9683610|reactome:R-HSA-9694631|go:"GO:0070213"(protein auto-ADP-ribosylation)|ensembl:ENSG00000151883(gene)|ensembl:ENST00000281631(transcript)|ensembl:ENST00000505697(transcript)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0006471"(protein ADP-ribosylation)|refseq:XP_011541934.2|refseq:XP_011541933.1|refseq:NP_001171526.1|refseq:NP_001171527.1|refseq:NP_078891.2 refseq:NP_005204.1|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR001713(Proteinase inhibitor I25A, stefin A)|mint:P01040|rcsb pdb:1CYU|rcsb pdb:1CYV|rcsb pdb:1DVC|rcsb pdb:1DVD|rcsb pdb:1GD3|rcsb pdb:1GD4|rcsb pdb:1N9J|rcsb pdb:1NB3|rcsb pdb:1NB5|rcsb pdb:3K9M|rcsb pdb:3KFQ|interpro:IPR018073|rcsb pdb:3KSE|reactome:R-HSA-6809371|ensembl:ENSG00000121552(gene)|ensembl:ENST00000264474(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002020"(protease binding)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0045861"(negative regulation of proteolysis) - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:40j9kPtn+p1lGYBXWsL+a6aKcyo9606 rogid:SzbpyWUHlOtItIvffzuwhcqFsDI9606 rigid:d4/W5keR9MGdw9KV+jJ9C+XKR9E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N3A8 uniprotkb:O60678 intact:EBI-8796778|ensembl:ENSP00000281631|ensembl:ENSP00000422217|uniprotkb:Q9H754|uniprotkb:Q3KRB7|uniprotkb:Q6DHZ1 intact:EBI-2809009|uniprotkb:B4DUC7|uniprotkb:A0A0A0MSN7|ensembl:ENSP00000331879 psi-mi:parp8_human(display_long)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 16(gene name synonym)|uniprotkb:PARP8(gene name)|psi-mi:PARP8(display_short)|uniprotkb:Poly [ADP-ribose] polymerase 8(gene name synonym) psi-mi:anm3_human(display_long)|uniprotkb:PRMT3(gene name)|psi-mi:PRMT3(display_short)|uniprotkb:HRMT1L3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482208|imex:IM-26985-493 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0140289"(protein mono-ADP-ribosylation)|go:"GO:1990404"(protein ADP-ribosylase activity)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|mint:Q8N3A8|reactome:R-HSA-197264|reactome:R-HSA-9683610|reactome:R-HSA-9694631|go:"GO:0070213"(protein auto-ADP-ribosylation)|ensembl:ENSG00000151883(gene)|ensembl:ENST00000281631(transcript)|ensembl:ENST00000505697(transcript)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0006471"(protein ADP-ribosylation)|refseq:XP_011541934.2|refseq:XP_011541933.1|refseq:NP_001171526.1|refseq:NP_001171527.1|refseq:NP_078891.2 refseq:NP_005779.1|ensembl:ENSG00000185238(gene)|ensembl:ENST00000331079(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0043022"(ribosome binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1900053"(negative regulation of retinoic acid biosynthetic process)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR025799|interpro:IPR029063|interpro:IPR036236|mint:O60678|rcsb pdb:2FYT|rcsb pdb:3SMQ|rcsb pdb:4HSG|rcsb pdb:4QQN|rcsb pdb:4RYL|reactome:R-HSA-3214858|reactome:R-HSA-8876725 - - comment:"author score: 57" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:40j9kPtn+p1lGYBXWsL+a6aKcyo9606 rogid:XtFHON3qMCvjDhtN8RpXJo9KODU9606 rigid:d4/W5keR9MGdw9KV+jJ9C+XKR9E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96J94 uniprotkb:O95816 intact:EBI-527417|uniprotkb:O95404|uniprotkb:Q8NA60|uniprotkb:Q8TBY5|uniprotkb:Q96JD5|uniprotkb:A4F266|ensembl:ENSP00000245255|ensembl:ENSP00000481042 intact:EBI-355275|uniprotkb:Q08AS9|uniprotkb:Q6FID0|uniprotkb:B4DXE2|ensembl:ENSP00000359727|intact:EBI-11068407 psi-mi:piwl1_human(display_long)|uniprotkb:PIWIL1(gene name)|psi-mi:PIWIL1(display_short)|uniprotkb:HIWI(gene name synonym) psi-mi:bag2_human(display_long)|uniprotkb:BAG2(gene name)|psi-mi:BAG2(display_short)|uniprotkb:Bcl-2-associated athanogene 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482526|imex:IM-26985-123 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-33534N|refseq:NP_001177900.1|refseq:NP_004755.2|refseq:XP_011537304.1|refseq:XP_011537305.1|refseq:XP_011537306.1|rcsb pdb:3O6E|rcsb pdb:3O7V|ensembl:ENSG00000125207(gene)|ensembl:ENSG00000275051(gene)|ensembl:ENST00000245255(transcript)|ensembl:ENST00000613226(transcript)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033391"(chromatoid body)|go:"GO:0034584"(piRNA binding)|go:"GO:0034587"(piRNA metabolic process)|go:"GO:0035093"(spermatogenesis, exchange of chromosomal proteins)|go:"GO:0043186"(P granule)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0097433"(dense body)|go:"GO:0140262"(mRNA cap binding complex binding)|go:"GO:1905538"(polysome binding)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR031320|interpro:IPR031326|interpro:IPR036085|interpro:IPR036397|mint:Q96J94|rcsb pdb:2L5C|rcsb pdb:2L5D|rcsb pdb:3O3I|rcsb pdb:6PI7|reactome:R-HSA-5601884 refseq:NP_004273.1|refseq:XP_011513301.1|refseq:XP_005249547.1|ensembl:ENSG00000112208(gene)|ensembl:ENST00000370693(transcript)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0019538"(protein metabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1901588"(dendritic microtubule)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|mint:O95816|reactome:R-HSA-3371453|refseq:XP_011513300.1 - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:cffy1VShng63XG+ArewNgwF/RQM9606 rogid:nBGGBIQc/3P0mwp7N/XuTGLOrg89606 rigid:xb2GaoKGkR6mMpU8R1Q869OI8TE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96J94 uniprotkb:Q9Y2W6 intact:EBI-527417|uniprotkb:O95404|uniprotkb:Q8NA60|uniprotkb:Q8TBY5|uniprotkb:Q96JD5|uniprotkb:A4F266|ensembl:ENSP00000245255|ensembl:ENSP00000481042 intact:EBI-12842466|ensembl:ENSP00000357812|ensembl:ENSP00000357815|ensembl:ENSP00000357819|ensembl:ENSP00000395718|uniprotkb:D3DV24|uniprotkb:Q5SZR3|uniprotkb:Q5SZR5|uniprotkb:Q8N582|uniprotkb:Q9NYV5 psi-mi:piwl1_human(display_long)|uniprotkb:PIWIL1(gene name)|psi-mi:PIWIL1(display_short)|uniprotkb:HIWI(gene name synonym) psi-mi:tdrkh_human(display_long)|uniprotkb:TDRKH(gene name)|psi-mi:TDRKH(display_short)|uniprotkb:TDRD2(gene name synonym)|uniprotkb:Tudor domain-containing protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482526|imex:IM-26985-123 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-33534N|refseq:NP_001177900.1|refseq:NP_004755.2|refseq:XP_011537304.1|refseq:XP_011537305.1|refseq:XP_011537306.1|rcsb pdb:3O6E|rcsb pdb:3O7V|ensembl:ENSG00000125207(gene)|ensembl:ENSG00000275051(gene)|ensembl:ENST00000245255(transcript)|ensembl:ENST00000613226(transcript)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033391"(chromatoid body)|go:"GO:0034584"(piRNA binding)|go:"GO:0034587"(piRNA metabolic process)|go:"GO:0035093"(spermatogenesis, exchange of chromosomal proteins)|go:"GO:0043186"(P granule)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0097433"(dense body)|go:"GO:0140262"(mRNA cap binding complex binding)|go:"GO:1905538"(polysome binding)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR014811(Region of unknown function DUF1785)|interpro:IPR031320|interpro:IPR031326|interpro:IPR036085|interpro:IPR036397|mint:Q96J94|rcsb pdb:2L5C|rcsb pdb:2L5D|rcsb pdb:3O3I|rcsb pdb:6PI7|reactome:R-HSA-5601884 ensembl:ENSG00000182134(gene)|ensembl:ENST00000368822(transcript)|ensembl:ENST00000368824(transcript)|ensembl:ENST00000368827(transcript)|ensembl:ENST00000458431(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009566"(fertilization)|go:"GO:0030154"(cell differentiation)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0034587"(piRNA metabolic process)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0071546"(pi-body)|go:"GO:0071547"(piP-body)|interpro:IPR002999(Tudor)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR035437|interpro:IPR036612|mint:Q9Y2W6|rcsb pdb:2DIQ|rcsb pdb:3FDR|rcsb pdb:5J39|rcsb pdb:6B57|rcsb pdb:6PI7|reactome:R-HSA-5601884|refseq:NP_001077432.1|refseq:NP_001077433.1|refseq:NP_001077434.1|refseq:NP_006853.2|refseq:XP_016855611.1|refseq:XP_016855612.1|refseq:XP_016855613.1|refseq:XP_016855614.1|refseq:XP_016855615.1|refseq:XP_016855616.1|dip:DIP-59459N - - comment:"author score: 52" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:cffy1VShng63XG+ArewNgwF/RQM9606 rogid:pP4akpV5Kqvd0p+5V750mkXASPg9606 rigid:xb2GaoKGkR6mMpU8R1Q869OI8TE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7RTV0 uniprotkb:P49790 intact:EBI-2555365|uniprotkb:Q9UH06|ensembl:ENSP00000216252 intact:EBI-286779|uniprotkb:Q5T9I7|intact:EBI-1237421|uniprotkb:E7EPX5|uniprotkb:Q4LE47|uniprotkb:Q7Z743|uniprotkb:B4DIK2|uniprotkb:F6QR24|ensembl:ENSP00000262077 psi-mi:phf5a_human(display_long)|uniprotkb:Splicing factor 3B-associated 14 kDa protein(gene name synonym)|uniprotkb:PHF5A(gene name)|psi-mi:PHF5A(display_short) psi-mi:nu153_human(display_long)|uniprotkb:Nucleoporin Nup153(gene name synonym)|uniprotkb:153 kDa nucleoporin(gene name synonym)|uniprotkb:NUP153(gene name)|psi-mi:NUP153(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482472|imex:IM-26985-121 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116147.1|ensembl:ENSG00000100410(gene)|ensembl:ENST00000216252(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR005345(PHF5-like)|mint:Q7RTV0|rcsb pdb:5IFE|rcsb pdb:5O9Z|rcsb pdb:5SYB|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:5ZYA|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|go:"GO:0048863"(stem cell differentiation) ensembl:ENSP00000262077|ensembl:ENST00000537253|ensembl:ENSP00000444029|ensembl:ENST00000613258|ensembl:ENSP00000478627|refseq:NP_005115.2|refseq:NP_001265138.1|refseq:NP_001265139.1|dip:DIP-38185N|ensembl:ENSG00000124789(gene)|ensembl:ENST00000262077(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042802"(identical protein binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043657"(host cell)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046832"(negative regulation of RNA export from nucleus)|go:"GO:0046872"(metal ion binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0075732"(viral penetration into host nucleus)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR013913(Nucleoporin, Nup153-like)|interpro:IPR018892|interpro:IPR026054|interpro:IPR036443|mint:P49790|rcsb pdb:2EBQ|rcsb pdb:2EBR|rcsb pdb:2EBV|rcsb pdb:2GQE|rcsb pdb:4U0C|rcsb pdb:4U0D|rcsb pdb:5TSV|rcsb pdb:5TSX|rcsb pdb:6AYA|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TrngLk+KyJ+qRs8HGvH1LZH2Tsg9606 rogid:rOax/ikcAu5fmDiCOauVr7Y/fzY9606 rigid:jzXZSO8XG9D/BO3F0VpzJYpf+bg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7RTV0 uniprotkb:Q15459 intact:EBI-2555365|uniprotkb:Q9UH06|ensembl:ENSP00000216252 intact:EBI-1054743|uniprotkb:E9PAW1|ensembl:ENSP00000215793 psi-mi:phf5a_human(display_long)|uniprotkb:Splicing factor 3B-associated 14 kDa protein(gene name synonym)|uniprotkb:PHF5A(gene name)|psi-mi:PHF5A(display_short) psi-mi:sf3a1_human(display_long)|uniprotkb:Spliceosome-associated protein 114(gene name synonym)|uniprotkb:SF3a120(gene name synonym)|uniprotkb:SF3A1(gene name)|psi-mi:SF3A1(display_short)|uniprotkb:SAP114(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482472|imex:IM-26985-121 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116147.1|ensembl:ENSG00000100410(gene)|ensembl:ENST00000216252(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR005345(PHF5-like)|mint:Q7RTV0|rcsb pdb:5IFE|rcsb pdb:5O9Z|rcsb pdb:5SYB|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:5ZYA|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|go:"GO:0048863"(stem cell differentiation) refseq:NP_005868.1|ensembl:ENSG00000099995(gene)|ensembl:ENST00000215793(transcript)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|rcsb pdb:2DT6|go:"GO:0071004"(U2-type prespliceosome)|rcsb pdb:2DT7|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6QX9|go:"GO:0071005"(U2-type precatalytic spliceosome)|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABI|reactome:R-HSA-72163|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1903241"(U2-type prespliceosome assembly)|interpro:IPR000061(SWAP/Surp)|interpro:IPR000626(Ubiquitin)|interpro:IPR022030|interpro:IPR029071|interpro:IPR035563|interpro:IPR035967|mint:Q15459|rcsb pdb:1ZKH|dip:DIP-29164N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TrngLk+KyJ+qRs8HGvH1LZH2Tsg9606 rogid:YrIs3RwfjUcDsHCJDgTLMnOUJZM9606 rigid:jzXZSO8XG9D/BO3F0VpzJYpf+bg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7RTV0 uniprotkb:Q12874 intact:EBI-2555365|uniprotkb:Q9UH06|ensembl:ENSP00000216252 intact:EBI-1051880|uniprotkb:Q15460|uniprotkb:Q5VT87|uniprotkb:D3DPT5|ensembl:ENSP00000362110 psi-mi:phf5a_human(display_long)|uniprotkb:Splicing factor 3B-associated 14 kDa protein(gene name synonym)|uniprotkb:PHF5A(gene name)|psi-mi:PHF5A(display_short) psi-mi:sf3a3_human(display_long)|uniprotkb:Spliceosome-associated protein 61(gene name synonym)|uniprotkb:SF3a60(gene name synonym)|uniprotkb:SF3A3(gene name)|psi-mi:SF3A3(display_short)|uniprotkb:SAP61(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482472|imex:IM-26985-121 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116147.1|ensembl:ENSG00000100410(gene)|ensembl:ENST00000216252(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR005345(PHF5-like)|mint:Q7RTV0|rcsb pdb:5IFE|rcsb pdb:5O9Z|rcsb pdb:5SYB|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:5ZYA|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|go:"GO:0048863"(stem cell differentiation) refseq:NP_006793.1|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1903241"(U2-type prespliceosome assembly)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR021966|interpro:IPR024598|interpro:IPR031774|interpro:IPR031776|mint:Q12874|rcsb pdb:2DT7|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|go:"GO:0000389"(mRNA 3'-splice site recognition)|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|reactome:R-HSA-72163|rcsb pdb:6Y53|ensembl:ENSG00000183431(gene)|ensembl:ENST00000373019(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|dip:DIP-882N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TrngLk+KyJ+qRs8HGvH1LZH2Tsg9606 rogid:fNjNguUOXqApr46rOAEpTs2geqY9606 rigid:jzXZSO8XG9D/BO3F0VpzJYpf+bg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7RTV0 uniprotkb:Q15428 intact:EBI-2555365|uniprotkb:Q9UH06|ensembl:ENSP00000216252 intact:EBI-2462271|uniprotkb:O75245|uniprotkb:B2RBU1|uniprotkb:D6W605|intact:EBI-28985293|ensembl:ENSP00000221494 psi-mi:phf5a_human(display_long)|uniprotkb:Splicing factor 3B-associated 14 kDa protein(gene name synonym)|uniprotkb:PHF5A(gene name)|psi-mi:PHF5A(display_short) psi-mi:sf3a2_human(display_long)|uniprotkb:SF3A2(gene name)|psi-mi:SF3A2(display_short)|uniprotkb:SAP62(gene name synonym)|uniprotkb:Spliceosome-associated protein 62(gene name synonym)|uniprotkb:SF3a66(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482472|imex:IM-26985-121 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116147.1|ensembl:ENSG00000100410(gene)|ensembl:ENST00000216252(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR005345(PHF5-like)|mint:Q7RTV0|rcsb pdb:5IFE|rcsb pdb:5O9Z|rcsb pdb:5SYB|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:5ZYA|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|go:"GO:0048863"(stem cell differentiation) refseq:NP_009096.2|ensembl:ENSP00000221494|dip:DIP-42521N|ensembl:ENSG00000104897(gene)|ensembl:ENST00000221494(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016607"(nuclear speck)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1903241"(U2-type prespliceosome assembly)|interpro:IPR000690(Zinc finger, C2H2-type matrin)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR031781|interpro:IPR036236|mint:Q15428|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|reactome:R-HSA-72163 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TrngLk+KyJ+qRs8HGvH1LZH2Tsg9606 rogid:ME4xzpqT37HjPl/xy683FS1Vns89606 rigid:jzXZSO8XG9D/BO3F0VpzJYpf+bg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7RTV0 uniprotkb:Q96F63 intact:EBI-2555365|uniprotkb:Q9UH06|ensembl:ENSP00000216252 intact:EBI-2555410|uniprotkb:Q96IF3|uniprotkb:Q658N6|ensembl:ENSP00000269967 psi-mi:phf5a_human(display_long)|uniprotkb:Splicing factor 3B-associated 14 kDa protein(gene name synonym)|uniprotkb:PHF5A(gene name)|psi-mi:PHF5A(display_short) psi-mi:ccd97_human(display_long)|uniprotkb:CCDC97(gene name)|psi-mi:CCDC97(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482472|imex:IM-26985-121 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116147.1|ensembl:ENSG00000100410(gene)|ensembl:ENST00000216252(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR005345(PHF5-like)|mint:Q7RTV0|rcsb pdb:5IFE|rcsb pdb:5O9Z|rcsb pdb:5SYB|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:5ZYA|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|go:"GO:0048863"(stem cell differentiation) refseq:NP_443080.1|ensembl:ENSG00000142039(gene)|ensembl:ENST00000269967(transcript)|interpro:IPR018613|interpro:IPR040233|mint:Q96F63 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TrngLk+KyJ+qRs8HGvH1LZH2Tsg9606 rogid:qNZAVYVMzqfscBiRFIA6CIMZaAY9606 rigid:jzXZSO8XG9D/BO3F0VpzJYpf+bg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7RTV0 uniprotkb:P09661 intact:EBI-2555365|uniprotkb:Q9UH06|ensembl:ENSP00000216252 intact:EBI-876439|uniprotkb:Q8TBD2|uniprotkb:B2R5I6|ensembl:ENSP00000254193 psi-mi:phf5a_human(display_long)|uniprotkb:Splicing factor 3B-associated 14 kDa protein(gene name synonym)|uniprotkb:PHF5A(gene name)|psi-mi:PHF5A(display_short) psi-mi:ru2a_human(display_long)|uniprotkb:SNRPA1(gene name)|psi-mi:SNRPA1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482472|imex:IM-26985-121 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116147.1|ensembl:ENSG00000100410(gene)|ensembl:ENST00000216252(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR005345(PHF5-like)|mint:Q7RTV0|rcsb pdb:5IFE|rcsb pdb:5O9Z|rcsb pdb:5SYB|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:5ZYA|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|go:"GO:0048863"(stem cell differentiation) refseq:NP_003081.2|dip:DIP-625N|ensembl:ENSG00000131876(gene)|ensembl:ENST00000254193(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0030620"(U2 snRNA binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003603(U2A'/phosphoprotein 32 family A, C-terminal)|interpro:IPR032675|interpro:IPR044640|mint:P09661|rcsb pdb:1A9N|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|reactome:R-HSA-72163|reactome:R-HSA-8950505 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TrngLk+KyJ+qRs8HGvH1LZH2Tsg9606 rogid:tmZyAPCvMg34GY4kVc6NcnycOeE9606 rigid:jzXZSO8XG9D/BO3F0VpzJYpf+bg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7RTV0 uniprotkb:P08579 intact:EBI-2555365|uniprotkb:Q9UH06|ensembl:ENSP00000216252 intact:EBI-1053651|uniprotkb:Q9UJD4|uniprotkb:B2R7J3|uniprotkb:D3DW21|ensembl:ENSP00000246071|ensembl:ENSP00000367178 psi-mi:phf5a_human(display_long)|uniprotkb:Splicing factor 3B-associated 14 kDa protein(gene name synonym)|uniprotkb:PHF5A(gene name)|psi-mi:PHF5A(display_short) psi-mi:ru2b_human(display_long)|uniprotkb:SNRPB2(gene name)|psi-mi:SNRPB2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482472|imex:IM-26985-121 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116147.1|ensembl:ENSG00000100410(gene)|ensembl:ENST00000216252(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR005345(PHF5-like)|mint:Q7RTV0|rcsb pdb:5IFE|rcsb pdb:5O9Z|rcsb pdb:5SYB|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:5ZYA|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|go:"GO:0048863"(stem cell differentiation) refseq:NP_003083.1|refseq:NP_937863.1|ensembl:ENSG00000125870(gene)|ensembl:ENST00000246071(transcript)|ensembl:ENST00000377943(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0016607"(nuclear speck)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0070990"(snRNP binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034562|interpro:IPR034564|interpro:IPR035979|mint:P08579|rcsb pdb:1A9N|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|reactome:R-HSA-72163 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TrngLk+KyJ+qRs8HGvH1LZH2Tsg9606 rogid:AzDL3wfFG4HmOfTs8NJL6bWjgrc9606 rigid:jzXZSO8XG9D/BO3F0VpzJYpf+bg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7RTV0 uniprotkb:Q9BWU0 intact:EBI-2555365|uniprotkb:Q9UH06|ensembl:ENSP00000216252 intact:EBI-1999704|uniprotkb:A6NJ39|uniprotkb:Q4KMT1|uniprotkb:Q4KMX0|uniprotkb:Q7Z5Q9|uniprotkb:Q9NVN2|ensembl:ENSP00000323837|ensembl:ENSP00000479964 psi-mi:phf5a_human(display_long)|uniprotkb:Splicing factor 3B-associated 14 kDa protein(gene name synonym)|uniprotkb:PHF5A(gene name)|psi-mi:PHF5A(display_short) psi-mi:nadap_human(display_long)|uniprotkb:SLC4A1AP(gene name)|psi-mi:SLC4A1AP(display_short)|uniprotkb:Kidney anion exchanger adapter protein(gene name synonym)|uniprotkb:Solute carrier family 4 anion exchanger member 1 adapter protein(gene name synonym)|uniprotkb:Human lung cancer oncogene 3 protein(gene name synonym)|uniprotkb:HLC3(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482472|imex:IM-26985-121 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116147.1|ensembl:ENSG00000100410(gene)|ensembl:ENST00000216252(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR005345(PHF5-like)|mint:Q7RTV0|rcsb pdb:5IFE|rcsb pdb:5O9Z|rcsb pdb:5SYB|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:5ZYA|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|go:"GO:0048863"(stem cell differentiation) refseq:NP_060628.2|ensembl:ENSG00000163798(gene)|ensembl:ENST00000326019(transcript)|ensembl:ENST00000613058(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|mint:Q9BWU0|rcsb pdb:4H87 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TrngLk+KyJ+qRs8HGvH1LZH2Tsg9606 rogid:z28F2N7dfIFPIVaNMT0gb05iRNw9606 rigid:jzXZSO8XG9D/BO3F0VpzJYpf+bg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7RTV0 uniprotkb:Q15427 intact:EBI-2555365|uniprotkb:Q9UH06|ensembl:ENSP00000216252 intact:EBI-348469|ensembl:ENSP00000271628|intact:EBI-1047735|uniprotkb:Q5SZ63 psi-mi:phf5a_human(display_long)|uniprotkb:Splicing factor 3B-associated 14 kDa protein(gene name synonym)|uniprotkb:PHF5A(gene name)|psi-mi:PHF5A(display_short) psi-mi:sf3b4_human(display_long)|uniprotkb:SF3B4(gene name)|psi-mi:SF3B4(display_short)|uniprotkb:SAP49(gene name synonym)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 49 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482472|imex:IM-26985-121 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116147.1|ensembl:ENSG00000100410(gene)|ensembl:ENST00000216252(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR005345(PHF5-like)|mint:Q7RTV0|rcsb pdb:5IFE|rcsb pdb:5O9Z|rcsb pdb:5SYB|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:5ZYA|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|go:"GO:0048863"(stem cell differentiation) refseq:NP_005841.1|ensembl:ENSG00000143368(gene)|ensembl:ENST00000271628(transcript)|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|rcsb pdb:6AHD|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034158|go:"GO:0000375"(RNA splicing, via transesterification reactions)|interpro:IPR034159|interpro:IPR035979|mint:Q15427|rcsb pdb:1X5T|rcsb pdb:5GVQ|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TrngLk+KyJ+qRs8HGvH1LZH2Tsg9606 rogid:Jgy6WmBFKkphpZLLte2GgsagUVI9606 rigid:jzXZSO8XG9D/BO3F0VpzJYpf+bg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7RTV0 uniprotkb:Q13435 intact:EBI-2555365|uniprotkb:Q9UH06|ensembl:ENSP00000216252 intact:EBI-749111|uniprotkb:A8K485|uniprotkb:B4DT19|uniprotkb:Q7Z627|uniprotkb:Q969K1|uniprotkb:Q96CM6|uniprotkb:Q9BWD2|intact:EBI-1052093|intact:EBI-2688256|uniprotkb:Q7L4T5|ensembl:ENSP00000318861 psi-mi:phf5a_human(display_long)|uniprotkb:Splicing factor 3B-associated 14 kDa protein(gene name synonym)|uniprotkb:PHF5A(gene name)|psi-mi:PHF5A(display_short) psi-mi:sf3b2_human(display_long)|uniprotkb:SF3B2(gene name)|psi-mi:SF3B2(display_short)|uniprotkb:SAP145(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 145 kDa subunit(gene name synonym)|uniprotkb:Spliceosome-associated protein 145(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482472|imex:IM-26985-121 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116147.1|ensembl:ENSG00000100410(gene)|ensembl:ENST00000216252(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR005345(PHF5-like)|mint:Q7RTV0|rcsb pdb:5IFE|rcsb pdb:5O9Z|rcsb pdb:5SYB|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:5ZYA|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|go:"GO:0048863"(stem cell differentiation) refseq:NP_006833.2|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR006568(PSP, proline-rich)|ensembl:ENSG00000087365(gene)|ensembl:ENST00000322535(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|interpro:IPR007180(Protein of unknown function DUF382)|rcsb pdb:2DO5|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y53|mint:Q13435|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165 - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TrngLk+KyJ+qRs8HGvH1LZH2Tsg9606 rogid:Y9uCV2x4J5kqyxeO8iXjojkXocA9606 rigid:jzXZSO8XG9D/BO3F0VpzJYpf+bg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7RTV0 uniprotkb:Q15393 intact:EBI-2555365|uniprotkb:Q9UH06|ensembl:ENSP00000216252 intact:EBI-346977|uniprotkb:Q6NTI8|uniprotkb:Q96GC0|uniprotkb:Q9BPY2|uniprotkb:Q9UFX7|uniprotkb:Q9UJ29|ensembl:ENSP00000305790 psi-mi:phf5a_human(display_long)|uniprotkb:Splicing factor 3B-associated 14 kDa protein(gene name synonym)|uniprotkb:PHF5A(gene name)|psi-mi:PHF5A(display_short) psi-mi:sf3b3_human(display_long)|uniprotkb:SF3B3(gene name)|psi-mi:SF3B3(display_short)|uniprotkb:KIAA0017(gene name synonym)|uniprotkb:SAP130(gene name synonym)|uniprotkb:Spliceosome-associated protein 130(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 130 kDa subunit(gene name synonym)|uniprotkb:STAF130(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482472|imex:IM-26985-121 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116147.1|ensembl:ENSG00000100410(gene)|ensembl:ENST00000216252(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR005345(PHF5-like)|mint:Q7RTV0|rcsb pdb:5IFE|rcsb pdb:5O9Z|rcsb pdb:5SYB|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:5ZYA|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|go:"GO:0048863"(stem cell differentiation) refseq:NP_036558.3|dip:DIP-28152N|ensembl:ENSG00000189091(gene)|ensembl:ENST00000302516(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|rcsb pdb:5O9Z|go:"GO:0005654"(nucleoplasm)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|go:"GO:0005730"(nucleolus)|go:"GO:0008380"(RNA splicing)|rcsb pdb:5ZYA|rcsb pdb:6AH0|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:6AHD|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR036322|mint:Q15393|rcsb pdb:5IFE - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TrngLk+KyJ+qRs8HGvH1LZH2Tsg9606 rogid:gnCSXjZ/bwNXair6kyQUKoKIwbM9606 rigid:jzXZSO8XG9D/BO3F0VpzJYpf+bg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7RTV0 uniprotkb:O75533 intact:EBI-2555365|uniprotkb:Q9UH06|ensembl:ENSP00000216252 intact:EBI-876542|ensembl:ENSP00000335321|uniprotkb:E9PCH3 psi-mi:phf5a_human(display_long)|uniprotkb:Splicing factor 3B-associated 14 kDa protein(gene name synonym)|uniprotkb:PHF5A(gene name)|psi-mi:PHF5A(display_short) psi-mi:sf3b1_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SF3b 155 kDa subunit(gene name synonym)|uniprotkb:Spliceosome-associated protein 155(gene name synonym)|uniprotkb:SF3B1(gene name)|psi-mi:SF3B1(display_short)|uniprotkb:SAP155(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482472|imex:IM-26985-121 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116147.1|ensembl:ENSG00000100410(gene)|ensembl:ENST00000216252(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR005345(PHF5-like)|mint:Q7RTV0|rcsb pdb:5IFE|rcsb pdb:5O9Z|rcsb pdb:5SYB|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:5ZYA|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|go:"GO:0048863"(stem cell differentiation) ensembl:ENSG00000115524(gene)|ensembl:ENST00000335508(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0034693"(U11/U12 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015016(Splicing factor 3B subunit 1)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038737|mint:O75533|rcsb pdb:2F9D|rcsb pdb:2F9J|rcsb pdb:2FHO|rcsb pdb:2PEH|rcsb pdb:3LQV|rcsb pdb:4OZ1|rcsb pdb:5IFE|rcsb pdb:5O9Z|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:5ZYA|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6N3E|refseq:NP_036565.2|dip:DIP-29411N|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-5250924|reactome:R-HSA-72163|reactome:R-HSA-72165 - - comment:"author score: 37" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TrngLk+KyJ+qRs8HGvH1LZH2Tsg9606 rogid:2KqZNVdZoItavA0DFR3zZ16U0tI9606 rigid:jzXZSO8XG9D/BO3F0VpzJYpf+bg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7RTV0 uniprotkb:Q9BWJ5 intact:EBI-2555365|uniprotkb:Q9UH06|ensembl:ENSP00000216252 intact:EBI-2555428|uniprotkb:Q7RTV1|uniprotkb:B2R568|ensembl:ENSP00000356541 psi-mi:phf5a_human(display_long)|uniprotkb:Splicing factor 3B-associated 14 kDa protein(gene name synonym)|uniprotkb:PHF5A(gene name)|psi-mi:PHF5A(display_short) psi-mi:sf3b5_human(display_long)|uniprotkb:SF3B10(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 10 kDa subunit(gene name synonym)|uniprotkb:SF3B5(gene name)|psi-mi:SF3B5(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482472|imex:IM-26985-121 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116147.1|ensembl:ENSG00000100410(gene)|ensembl:ENST00000216252(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR005345(PHF5-like)|mint:Q7RTV0|rcsb pdb:5IFE|rcsb pdb:5O9Z|rcsb pdb:5SYB|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:5ZYA|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|go:"GO:0048863"(stem cell differentiation) refseq:NP_112577.1|ensembl:ENSG00000169976(gene)|ensembl:ENST00000367569(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR009846(Splicing factor 3B subunit 5/RDS3 complex subunit 10)|interpro:IPR017089(Splicing factor 3B, subunit 5)|mint:Q9BWJ5|rcsb pdb:5IFE|rcsb pdb:5O9Z|rcsb pdb:5Z56|rcsb pdb:5Z58|rcsb pdb:5ZYA|rcsb pdb:6AH0|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|rcsb pdb:5Z57 - - comment:"author score: 47" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TrngLk+KyJ+qRs8HGvH1LZH2Tsg9606 rogid:wuQBsSytGhSg64IQSmEJXe+26zQ9606 rigid:jzXZSO8XG9D/BO3F0VpzJYpf+bg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7RTV0 uniprotkb:Q9Y3B4 intact:EBI-2555365|uniprotkb:Q9UH06|ensembl:ENSP00000216252 intact:EBI-1046261|ensembl:ENSP00000233468|uniprotkb:Q53TM1 psi-mi:phf5a_human(display_long)|uniprotkb:Splicing factor 3B-associated 14 kDa protein(gene name synonym)|uniprotkb:PHF5A(gene name)|psi-mi:PHF5A(display_short) psi-mi:sf3b6_human(display_long)|uniprotkb:SF3B6(gene name)|psi-mi:SF3B6(display_short)|uniprotkb:Pre-mRNA branch site protein p14(gene name synonym)|uniprotkb:SAP14(gene name synonym)|uniprotkb:SF3B14(gene name synonym)|uniprotkb:SF3B14A(gene name synonym)|uniprotkb:SF3b 14 kDa subunit(gene name synonym)|uniprotkb:Spliceosome-associated protein, 14-kDa(gene name synonym)|uniprotkb:Splicing factor 3b, subunit 6, 14kDa(gene name synonym)|uniprotkb:CGI-110(orf name)|uniprotkb:HSPC175(orf name)|uniprotkb:HT006(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482472|imex:IM-26985-121 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116147.1|ensembl:ENSG00000100410(gene)|ensembl:ENST00000216252(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR005345(PHF5-like)|mint:Q7RTV0|rcsb pdb:5IFE|rcsb pdb:5O9Z|rcsb pdb:5SYB|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:5ZYA|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|go:"GO:0048863"(stem cell differentiation) ensembl:ENST00000233468(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001825"(blastocyst formation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|ensembl:ENSG00000115128(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034150|interpro:IPR035979|mint:Q9Y3B4|rcsb pdb:2F9D|rcsb pdb:2F9J|rcsb pdb:2FHO|rcsb pdb:3LQV|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:NP_057131.1|dip:DIP-44132N - - comment:"author score: 54" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TrngLk+KyJ+qRs8HGvH1LZH2Tsg9606 rogid:7mhaXkmVqjfJGPdX1UDM+kN4vNI9606 rigid:jzXZSO8XG9D/BO3F0VpzJYpf+bg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7RTV0 uniprotkb:Q9GZS3 intact:EBI-2555365|uniprotkb:Q9UH06|ensembl:ENSP00000216252 intact:EBI-358545|uniprotkb:D3DW84|uniprotkb:Q6IA22|uniprotkb:Q7Z4X4|ensembl:ENSP00000267973|ensembl:ENSP00000453801 psi-mi:phf5a_human(display_long)|uniprotkb:Splicing factor 3B-associated 14 kDa protein(gene name synonym)|uniprotkb:PHF5A(gene name)|psi-mi:PHF5A(display_short) psi-mi:wdr61_human(display_long)|uniprotkb:WDR61(gene name)|psi-mi:WDR61(display_short)|uniprotkb:Meiotic recombination REC14 protein homolog(gene name synonym)|uniprotkb:SKI8 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482472|imex:IM-26985-121 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116147.1|ensembl:ENSG00000100410(gene)|ensembl:ENST00000216252(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR005345(PHF5-like)|mint:Q7RTV0|rcsb pdb:5IFE|rcsb pdb:5O9Z|rcsb pdb:5SYB|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:5ZYA|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|go:"GO:0048863"(stem cell differentiation) refseq:NP_079510.1|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9GZS3|rcsb pdb:3OW8|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-429958|reactome:R-HSA-674695|reactome:R-HSA-75955|ensembl:ENSG00000140395(gene)|ensembl:ENST00000267973(transcript)|ensembl:ENST00000558311(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0055087"(Ski complex)|reactome:R-HSA-8866654|refseq:XP_011520396.1|refseq:NP_001290176.1|refseq:NP_001290177.1|dip:DIP-36672N - - comment:"author score: 59" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TrngLk+KyJ+qRs8HGvH1LZH2Tsg9606 rogid:yVcjv2BXXr3VFSR7OcJ/1u9L6gw9606 rigid:jzXZSO8XG9D/BO3F0VpzJYpf+bg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7RTV0 uniprotkb:Q6PID6 intact:EBI-2555365|uniprotkb:Q9UH06|ensembl:ENSP00000216252 intact:EBI-2555404|uniprotkb:O95105|uniprotkb:B2R6G0|ensembl:ENSP00000338533 psi-mi:phf5a_human(display_long)|uniprotkb:Splicing factor 3B-associated 14 kDa protein(gene name synonym)|uniprotkb:PHF5A(gene name)|psi-mi:PHF5A(display_short) psi-mi:ttc33_human(display_long)|uniprotkb:Osmosis-responsive factor(gene name synonym)|uniprotkb:TTC33(gene name)|psi-mi:TTC33(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482472|imex:IM-26985-121 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_116147.1|ensembl:ENSG00000100410(gene)|ensembl:ENST00000216252(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR005345(PHF5-like)|mint:Q7RTV0|rcsb pdb:5IFE|rcsb pdb:5O9Z|rcsb pdb:5SYB|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:5ZYA|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|go:"GO:0048863"(stem cell differentiation) refseq:NP_036514.1|refseq:XP_011512305.1|ensembl:ENSG00000113638(gene)|ensembl:ENST00000337702(transcript)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q6PID6 - - comment:"author score: 70" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:TrngLk+KyJ+qRs8HGvH1LZH2Tsg9606 rogid:E83noPN1tHU7Ow6YNDDE+vuJkHo9606 rigid:jzXZSO8XG9D/BO3F0VpzJYpf+bg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BUL5 uniprotkb:P01743 intact:EBI-722852|uniprotkb:A1DZ74|uniprotkb:Q8IZK0|uniprotkb:Q96HG7|uniprotkb:Q9H5X0|intact:EBI-28985443|ensembl:ENSP00000322579|uniprotkb:B4DLK6|uniprotkb:B3KVH8|uniprotkb:D3DTN4 intact:EBI-25418662|ensembl:ENSP00000375031|ensembl:ENSP00000488713|uniprotkb:A0A0B4J1V4|uniprotkb:P06326|uniprotkb:P80421 psi-mi:phf23_human(display_long)|uniprotkb:PDH-containing protein JUNE-1(gene name synonym)|uniprotkb:PHF23(gene name)|psi-mi:PHF23(display_short) psi-mi:hv146_human(display_long)|uniprotkb:IGHV1-46(gene name)|psi-mi:IGHV1-46(display_short)|uniprotkb:Ig heavy chain V-I region DOT(gene name synonym)|uniprotkb:Ig heavy chain V-I region HG3(gene name synonym)|uniprotkb:Ig heavy chain V-I region Mot(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482457|imex:IM-26985-561 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271446.1|refseq:NP_001271447.1|refseq:NP_077273.2|ensembl:ENSG00000040633(gene)|ensembl:ENST00000320316(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006914"(autophagy)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1901097"(negative regulation of autophagosome maturation)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|mint:Q9BUL5|rcsb pdb:6WXK|ensembl:ENST00000454255|ensembl:ENSP00000414607|ensembl:ENST00000571362|ensembl:ENSP00000460738|ensembl:ENSP00000322579 reactome:R-HSA-2871809|ensembl:ENSG00000211962(gene)|ensembl:ENSG00000282131(gene)|ensembl:ENST00000390622(transcript)|ensembl:ENST00000632105(transcript)|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0034987"(immunoglobulin receptor binding)|go:"GO:0042571"(immunoglobulin complex, circulating)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050871"(positive regulation of B cell activation)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|mint:P01743|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-5690714|reactome:R-HSA-9664323|reactome:R-HSA-9664422|reactome:R-HSA-977606|reactome:R-HSA-983695|reactome:R-HSA-2871837 - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:KD4rKZSoxyxX7U3GOa9BtF6EGco9606 rogid:DT3St0YpBK1Zd7HxjR6b/w+/2oE9606 rigid:Pgyhk9b4ThGAT2Wfu7UbrxhcpRw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BUL5 uniprotkb:P0CG04 intact:EBI-722852|uniprotkb:A1DZ74|uniprotkb:Q8IZK0|uniprotkb:Q96HG7|uniprotkb:Q9H5X0|intact:EBI-28985443|ensembl:ENSP00000322579|uniprotkb:B4DLK6|uniprotkb:B3KVH8|uniprotkb:D3DTN4 intact:EBI-1221063|uniprotkb:P80423|uniprotkb:A0M8Q4|uniprotkb:P01842|uniprotkb:A0A075B6K8 psi-mi:phf23_human(display_long)|uniprotkb:PDH-containing protein JUNE-1(gene name synonym)|uniprotkb:PHF23(gene name)|psi-mi:PHF23(display_short) psi-mi:iglc1_human(display_long)|uniprotkb:IGLC1(gene name)|psi-mi:IGLC1(display_short)|uniprotkb:Ig lambda chain C region MGC(gene name synonym)|uniprotkb:Ig lambda-1 chain C region(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482457|imex:IM-26985-561 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271446.1|refseq:NP_001271447.1|refseq:NP_077273.2|ensembl:ENSG00000040633(gene)|ensembl:ENST00000320316(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006914"(autophagy)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1901097"(negative regulation of autophagosome maturation)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|mint:Q9BUL5|rcsb pdb:6WXK|ensembl:ENST00000454255|ensembl:ENSP00000414607|ensembl:ENST00000571362|ensembl:ENSP00000460738|ensembl:ENSP00000322579 interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|mint:P0CG04|interpro:IPR036179|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0034987"(immunoglobulin receptor binding)|go:"GO:0042571"(immunoglobulin complex, circulating)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|rcsb pdb:1ZVO|rcsb pdb:2FB4|rcsb pdb:2IG2|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|go:"GO:0045087"(innate immune response)|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664422|reactome:R-HSA-977606|reactome:R-HSA-983695|reactome:R-HSA-9664323 - - comment:"author score: 36" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:KD4rKZSoxyxX7U3GOa9BtF6EGco9606 rogid:OOdxBXPI2Jzf9HxurFZjk3/L1DM9606 rigid:Pgyhk9b4ThGAT2Wfu7UbrxhcpRw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BUL5 uniprotkb:P53701 intact:EBI-722852|uniprotkb:A1DZ74|uniprotkb:Q8IZK0|uniprotkb:Q96HG7|uniprotkb:Q9H5X0|intact:EBI-28985443|ensembl:ENSP00000322579|uniprotkb:B4DLK6|uniprotkb:B3KVH8|uniprotkb:D3DTN4 intact:EBI-10763431|uniprotkb:B3KUS1|uniprotkb:Q502X8|ensembl:ENSP00000326579|ensembl:ENSP00000370139|ensembl:ENSP00000370140 psi-mi:phf23_human(display_long)|uniprotkb:PDH-containing protein JUNE-1(gene name synonym)|uniprotkb:PHF23(gene name)|psi-mi:PHF23(display_short) psi-mi:cchl_human(display_long)|uniprotkb:Cytochrome c-type heme lyase(gene name synonym)|uniprotkb:HCCS(gene name)|psi-mi:HCCS(display_short)|uniprotkb:CCHL(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482457|imex:IM-26985-561 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001271446.1|refseq:NP_001271447.1|refseq:NP_077273.2|ensembl:ENSG00000040633(gene)|ensembl:ENST00000320316(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006914"(autophagy)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1901097"(negative regulation of autophagosome maturation)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|mint:Q9BUL5|rcsb pdb:6WXK|ensembl:ENST00000454255|ensembl:ENSP00000414607|ensembl:ENST00000571362|ensembl:ENSP00000460738|ensembl:ENSP00000322579 refseq:NP_001116080.1|refseq:NP_001165462.1|refseq:NP_005324.3|ensembl:ENSG00000004961(gene)|ensembl:ENST00000321143(transcript)|ensembl:ENST00000380762(transcript)|ensembl:ENST00000380763(transcript)|go:"GO:0004408"(holocytochrome-c synthase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016020"(membrane)|go:"GO:0018063"(cytochrome c-heme linkage)|go:"GO:0020037"(heme binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000511(Cytochrome c and c1 haem-lyase)|mint:P53701 - - comment:"author score: 78" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:KD4rKZSoxyxX7U3GOa9BtF6EGco9606 rogid:bJhUeXcA+kpWK7qF33e5hBwQops9606 rigid:Pgyhk9b4ThGAT2Wfu7UbrxhcpRw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96EK2 uniprotkb:Q5PSV4 intact:EBI-16472119|ensembl:ENSP00000324403|uniprotkb:B0QYW3|uniprotkb:B0QYW4|uniprotkb:B3KRU4|uniprotkb:B7Z4F8|uniprotkb:Q5TFL2|uniprotkb:Q6ICC0 intact:EBI-5666615|intact:EBI-11060846|uniprotkb:Q9BRI4|uniprotkb:A6NFW5|uniprotkb:A6NH45|uniprotkb:B2RD65|ensembl:ENSP00000216807 psi-mi:pf21b_human(display_long)|uniprotkb:PHF21B(gene name)|psi-mi:PHF21B(display_short)|uniprotkb:KIAA1661(gene name synonym) psi-mi:brm1l_human(display_long)|uniprotkb:BRMS1-homolog protein p40(gene name synonym)|uniprotkb:BRMS1-like protein p40(gene name synonym)|uniprotkb:BRMS1L(gene name)|psi-mi:BRMS1L(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482406|imex:IM-26985-419 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000056487(gene)|ensembl:ENST00000313237(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|mint:Q96EK2|refseq:NP_001129334.1|refseq:NP_001229379.1|refseq:NP_001271225.1|refseq:NP_612424.1|refseq:XP_006724185.1 refseq:XP_006720338.1|refseq:NP_115728.2|refseq:XP_016877193.1|refseq:XP_016877194.1|ensembl:ENSG00000100916(gene)|ensembl:ENST00000216807(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0016575"(histone deacetylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0070822"(Sin3-type complex)|interpro:IPR013907(Sds3-like)|mint:Q5PSV4 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FhssIBtwxKIFiyGylNLhTTFcyrI9606 rogid:jVvtmlOL9vQdYz5kAnOi6GksVng9606 rigid:7NjI4eHLAdqggBuMeiILRJUlWBI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96EK2 uniprotkb:P04040 intact:EBI-16472119|ensembl:ENSP00000324403|uniprotkb:B0QYW3|uniprotkb:B0QYW4|uniprotkb:B3KRU4|uniprotkb:B7Z4F8|uniprotkb:Q5TFL2|uniprotkb:Q6ICC0 intact:EBI-2432181|uniprotkb:A8K6C0|uniprotkb:B2RCZ9|uniprotkb:Q9UC85|uniprotkb:Q2M1U4|uniprotkb:Q4VXX5|uniprotkb:Q9BWT9|uniprotkb:D3DR07|ensembl:ENSP00000241052 psi-mi:pf21b_human(display_long)|uniprotkb:PHF21B(gene name)|psi-mi:PHF21B(display_short)|uniprotkb:KIAA1661(gene name synonym) psi-mi:cata_human(display_long)|uniprotkb:CAT(gene name)|psi-mi:CAT(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482406|imex:IM-26985-419 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000056487(gene)|ensembl:ENST00000313237(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|mint:Q96EK2|refseq:NP_001129334.1|refseq:NP_001229379.1|refseq:NP_001271225.1|refseq:NP_612424.1|refseq:XP_006724185.1 refseq:NP_001743.1|ensembl:ENSG00000121691(gene)|ensembl:ENST00000241052(transcript)|go:"GO:0000268"(peroxisome targeting sequence binding)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004046"(aminoacylase activity)|go:"GO:0004096"(catalase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005764"(lysosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007568"(aging)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009060"(aerobic respiration)|go:"GO:0009642"(response to light intensity)|go:"GO:0009650"(UV protection)|go:"GO:0010193"(response to ozone)|go:"GO:0010288"(response to lead ion)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014823"(response to activity)|go:"GO:0014854"(response to inactivity)|go:"GO:0016020"(membrane)|go:"GO:0016209"(antioxidant activity)|go:"GO:0016684"(oxidoreductase activity, acting on peroxide as acceptor)|go:"GO:0019899"(enzyme binding)|go:"GO:0020027"(hemoglobin metabolic process)|go:"GO:0020037"(heme binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032355"(response to estradiol)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033189"(response to vitamin A)|go:"GO:0033197"(response to vitamin E)|go:"GO:0033591"(response to L-ascorbic acid)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045471"(response to ethanol)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0046872"(metal ion binding)|go:"GO:0050661"(NADP binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0080184"(response to phenylpropanoid)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002226(Catalase)|interpro:IPR010582(Catalase-related)|interpro:IPR011614(Catalase, N-terminal)|interpro:IPR018028|interpro:IPR020835|interpro:IPR024708|interpro:IPR024711|interpro:IPR040333|mint:P04040|rcsb pdb:1DGB|rcsb pdb:1DGF|rcsb pdb:1DGG|rcsb pdb:1DGH|rcsb pdb:1F4J|rcsb pdb:1QQW|reactome:R-HSA-3299685|reactome:R-HSA-6798695|reactome:R-HSA-9033241|reactome:R-HSA-9615017 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FhssIBtwxKIFiyGylNLhTTFcyrI9606 rogid:IWdPQIuCq9vCj8I0HmshkJwAAqg9606 rigid:7NjI4eHLAdqggBuMeiILRJUlWBI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96EK2 uniprotkb:Q96ST3 intact:EBI-16472119|ensembl:ENSP00000324403|uniprotkb:B0QYW3|uniprotkb:B0QYW4|uniprotkb:B3KRU4|uniprotkb:B7Z4F8|uniprotkb:Q5TFL2|uniprotkb:Q6ICC0 intact:EBI-347218|uniprotkb:Q8N8N4|uniprotkb:Q8NC83|uniprotkb:Q8WV18|uniprotkb:Q96L98|uniprotkb:Q9UFQ1|intact:EBI-28985143|ensembl:ENSP00000353622|ensembl:ENSP00000378402|ensembl:ENSP00000378403|uniprotkb:B2RNS5 psi-mi:pf21b_human(display_long)|uniprotkb:PHF21B(gene name)|psi-mi:PHF21B(display_short)|uniprotkb:KIAA1661(gene name synonym) psi-mi:sin3a_human(display_long)|uniprotkb:SIN3A(gene name)|psi-mi:SIN3A(display_short)|uniprotkb:Transcriptional corepressor Sin3a(gene name synonym)|uniprotkb:Histone deacetylase complex subunit Sin3a(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482406|imex:IM-26985-419 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000056487(gene)|ensembl:ENST00000313237(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|mint:Q96EK2|refseq:NP_001129334.1|refseq:NP_001229379.1|refseq:NP_001271225.1|refseq:NP_612424.1|refseq:XP_006724185.1 refseq:XP_006720528.1|ensembl:ENSG00000169375(gene)|ensembl:ENST00000360439(transcript)|ensembl:ENST00000394947(transcript)|ensembl:ENST00000394949(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007568"(aging)|go:"GO:0010817"(regulation of hormone levels)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0031937"(obsolete positive regulation of chromatin silencing)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0051595"(response to methylglyoxal)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1901675"(negative regulation of histone H3-K27 acetylation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR003822(Paired amphipathic helix)|interpro:IPR013194(Histone deacetylase interacting)|interpro:IPR031693|interpro:IPR036600|interpro:IPR037969|interpro:IPR039774|mint:Q96ST3|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-427413|reactome:R-HSA-8936459|reactome:R-HSA-9022538|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9022702|rcsb pdb:1PO4|reactome:R-HSA-9615017|reactome:R-HSA-9707564|reactome:R-HSA-983231|refseq:XP_006720529.1|refseq:XP_006720530.1|refseq:NP_001138829.1|refseq:NP_001138830.1|refseq:NP_056292.1|ensembl:ENSP00000353622|ensembl:ENSP00000378402|ensembl:ENSP00000378403|dip:DIP-31515N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FhssIBtwxKIFiyGylNLhTTFcyrI9606 rogid:pO/FziDcMNQRfy6ePi6eNKELXVM9606 rigid:7NjI4eHLAdqggBuMeiILRJUlWBI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96EK2 uniprotkb:P24158 intact:EBI-16472119|ensembl:ENSP00000324403|uniprotkb:B0QYW3|uniprotkb:B0QYW4|uniprotkb:B3KRU4|uniprotkb:B7Z4F8|uniprotkb:Q5TFL2|uniprotkb:Q6ICC0 intact:EBI-465028|uniprotkb:Q9UQD8|ensembl:ENSP00000234347|ensembl:ENSP00000478977|uniprotkb:P15637|uniprotkb:P18078|uniprotkb:Q4VB09|uniprotkb:Q6LBM7|uniprotkb:Q4VB08|uniprotkb:Q6LBN2|uniprotkb:Q9UD25 psi-mi:pf21b_human(display_long)|uniprotkb:PHF21B(gene name)|psi-mi:PHF21B(display_short)|uniprotkb:KIAA1661(gene name synonym) psi-mi:prtn3_human(display_long)|uniprotkb:MBN(gene name synonym)|uniprotkb:PRTN3(gene name)|psi-mi:PRTN3(display_short)|uniprotkb:Leukocyte proteinase 3(gene name synonym)|uniprotkb:AGP7(gene name synonym)|uniprotkb:Wegener autoantigen(gene name synonym)|uniprotkb:P29(gene name synonym)|uniprotkb:C-ANCA antigen(gene name synonym)|uniprotkb:Neutrophil proteinase 4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482406|imex:IM-26985-419 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000056487(gene)|ensembl:ENST00000313237(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|mint:Q96EK2|refseq:NP_001129334.1|refseq:NP_001229379.1|refseq:NP_001271225.1|refseq:NP_612424.1|refseq:XP_006724185.1 ensembl:ENSG00000196415(gene)|ensembl:ENSG00000277804(gene)|ensembl:ENST00000234347(transcript)|ensembl:ENST00000612112(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006909"(phagocytosis)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0019899"(enzyme binding)|go:"GO:0030574"(collagen catabolic process)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045217"(cell-cell junction maintenance)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072672"(neutrophil extravasation)|go:"GO:0097029"(mature conventional dendritic cell differentiation)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|mint:P24158|rcsb pdb:1FUJ|reactome:R-HSA-140875|reactome:R-HSA-449836|reactome:R-HSA-6798695|reactome:R-HSA-6803157|interpro:IPR001314(Peptidase S1A, chymotrypsin)|refseq:NP_002768.3|dip:DIP-31107N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FhssIBtwxKIFiyGylNLhTTFcyrI9606 rogid:+28oFrY+yAY4MtIR0vfAfItyhrM9606 rigid:7NjI4eHLAdqggBuMeiILRJUlWBI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96EK2 uniprotkb:O75150 intact:EBI-16472119|ensembl:ENSP00000324403|uniprotkb:B0QYW3|uniprotkb:B0QYW4|uniprotkb:B3KRU4|uniprotkb:B7Z4F8|uniprotkb:Q5TFL2|uniprotkb:Q6ICC0 intact:EBI-744408|uniprotkb:Q6AHZ6|uniprotkb:Q6N005|uniprotkb:Q7L3T6|uniprotkb:Q8N615|uniprotkb:Q96T18|uniprotkb:Q9BSV9|uniprotkb:Q9HC82|ensembl:ENSP00000325677|uniprotkb:A0A024QZG0 psi-mi:pf21b_human(display_long)|uniprotkb:PHF21B(gene name)|psi-mi:PHF21B(display_short)|uniprotkb:KIAA1661(gene name synonym) psi-mi:bre1b_human(display_long)|uniprotkb:95 kDa retinoblastoma-associated protein(gene name synonym)|uniprotkb:RING finger protein 40(gene name synonym)|uniprotkb:RNF40(gene name)|psi-mi:RNF40(display_short)|uniprotkb:BRE1B(gene name synonym)|uniprotkb:KIAA0661(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase BRE1B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482406|imex:IM-26985-419 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000056487(gene)|ensembl:ENST00000313237(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|mint:Q96EK2|refseq:NP_001129334.1|refseq:NP_001229379.1|refseq:NP_001271225.1|refseq:NP_612424.1|refseq:XP_006724185.1 refseq:NP_001273501.1|refseq:NP_001193962.1|refseq:NP_001193963.1|refseq:NP_055586.1|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1902916"(positive regulation of protein polyubiquitination)|go:"GO:2001168"(positive regulation of histone H2B ubiquitination)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013956(E3 ubiquitin ligase, BRE1)|interpro:IPR017907|mint:O75150|reactome:R-HSA-8866654|go:"GO:0046872"(metal ion binding)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043679"(axon terminus)|go:"GO:0044877"(protein-containing complex binding)|ensembl:ENSG00000103549(gene)|ensembl:ENST00000324685(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031624"(ubiquitin conjugating enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033503"(HULC complex) - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FhssIBtwxKIFiyGylNLhTTFcyrI9606 rogid:POkQZhEBe4cw3Y9V3YOwJDgvYJ89606 rigid:7NjI4eHLAdqggBuMeiILRJUlWBI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96EK2 uniprotkb:Q13547 intact:EBI-16472119|ensembl:ENSP00000324403|uniprotkb:B0QYW3|uniprotkb:B0QYW4|uniprotkb:B3KRU4|uniprotkb:B7Z4F8|uniprotkb:Q5TFL2|uniprotkb:Q6ICC0 intact:EBI-301834|uniprotkb:Q92534|ensembl:ENSP00000362649 psi-mi:pf21b_human(display_long)|uniprotkb:PHF21B(gene name)|psi-mi:PHF21B(display_short)|uniprotkb:KIAA1661(gene name synonym) psi-mi:hdac1_human(display_long)|uniprotkb:HDAC1(gene name)|psi-mi:HDAC1(display_short)|uniprotkb:RPD3L1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482406|imex:IM-26985-419 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000056487(gene)|ensembl:ENST00000313237(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|mint:Q96EK2|refseq:NP_001129334.1|refseq:NP_001229379.1|refseq:NP_001271225.1|refseq:NP_612424.1|refseq:XP_006724185.1 ensembl:ENSG00000116478(gene)|ensembl:ENST00000373548(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001975"(response to amphetamine)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007492"(endoderm development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031000"(response to caffeine)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043044"|go:"GO:0019213"(deacetylase activity)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070888"(E-box binding)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900221"(regulation of amyloid-beta clearance)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000343"("positive regulation of chemokine (C-X-C motif) ligand 2 production")|go:"GO:2000676"(positive regulation of type B pancreatic cell apoptotic process)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q13547|rcsb pdb:1TYI|rcsb pdb:4BKX|rcsb pdb:5ICN|rcsb pdb:6Z2J|rcsb pdb:6Z2K|rcsb pdb:7AO8|rcsb pdb:7AO9|rcsb pdb:7AOA|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-193670|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-3769402|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-4641265|reactome:R-HSA-6804758|reactome:R-HSA-69205|reactome:R-HSA-73762|reactome:R-HSA-8936459|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9022538|reactome:R-HSA-9022692|go:"GO:0017053"(transcription repressor complex)|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-9022699|reactome:R-HSA-9022702|reactome:R-HSA-9615017|reactome:R-HSA-9679191|reactome:R-HSA-983231|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0052548"(regulation of endopeptidase activity)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:NP_004955.2|dip:DIP-24184N - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FhssIBtwxKIFiyGylNLhTTFcyrI9606 rogid:RP+yIBWH55NgoPTY1nKXqeJL/xY9606 rigid:7NjI4eHLAdqggBuMeiILRJUlWBI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96EK2 uniprotkb:P05109 intact:EBI-16472119|ensembl:ENSP00000324403|uniprotkb:B0QYW3|uniprotkb:B0QYW4|uniprotkb:B3KRU4|uniprotkb:B7Z4F8|uniprotkb:Q5TFL2|uniprotkb:Q6ICC0 intact:EBI-355281|uniprotkb:Q5SY70|uniprotkb:Q9UC92|uniprotkb:Q9UCJ0|uniprotkb:A8K5L3|uniprotkb:Q9UC84|uniprotkb:Q9UCM6|uniprotkb:D3DV37|ensembl:ENSP00000357721|ensembl:ENSP00000357722 psi-mi:pf21b_human(display_long)|uniprotkb:PHF21B(gene name)|psi-mi:PHF21B(display_short)|uniprotkb:KIAA1661(gene name synonym) psi-mi:s10a8_human(display_long)|uniprotkb:S100A8(gene name)|psi-mi:S100A8(display_short)|uniprotkb:CAGA(gene name synonym)|uniprotkb:MRP8(gene name synonym)|uniprotkb:CFAG(gene name synonym)|uniprotkb:S100 calcium-binding protein A8(gene name synonym)|uniprotkb:Calgranulin-A(gene name synonym)|uniprotkb:Migration inhibitory factor-related protein 8(gene name synonym)|uniprotkb:Cystic fibrosis antigen(gene name synonym)|uniprotkb:Leukocyte L1 complex light chain(gene name synonym)|uniprotkb:Calprotectin L1L subunit(gene name synonym)|uniprotkb:Urinary stone protein band A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482406|imex:IM-26985-419 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000056487(gene)|ensembl:ENST00000313237(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|mint:Q96EK2|refseq:NP_001129334.1|refseq:NP_001229379.1|refseq:NP_001271225.1|refseq:NP_612424.1|refseq:XP_006724185.1 refseq:NP_001306126.1|refseq:NP_001306127.1|refseq:NP_001306130.1|refseq:NP_002955.2|go:"GO:0042060"(wound healing)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045471"(response to ethanol)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070488"(neutrophil aggregation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028474|go:"GO:0035662"(Toll-like receptor 4 binding)|mint:P05109|rcsb pdb:1MR8|rcsb pdb:1XK4|rcsb pdb:4GGF|rcsb pdb:4XJK|rcsb pdb:5HLO|rcsb pdb:5HLV|rcsb pdb:5W1F|rcsb pdb:6DS2|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5668599|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-6799990|ensembl:ENST00000368732(transcript)|ensembl:ENST00000368733(transcript)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002526"(acute inflammatory response)|ensembl:ENSG00000143546(gene)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0002793"(positive regulation of peptide secretion)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010043"(response to zinc ion)|go:"GO:0014002"(astrocyte development)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032119"(sequestering of zinc ion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035425"(autocrine signaling)|dip:DIP-1165N - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FhssIBtwxKIFiyGylNLhTTFcyrI9606 rogid:3Okfhj8fxclZ0Uo/Fa1Z89qC8Ec9606 rigid:7NjI4eHLAdqggBuMeiILRJUlWBI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96EK2 uniprotkb:P06702 intact:EBI-16472119|ensembl:ENSP00000324403|uniprotkb:B0QYW3|uniprotkb:B0QYW4|uniprotkb:B3KRU4|uniprotkb:B7Z4F8|uniprotkb:Q5TFL2|uniprotkb:Q6ICC0 intact:EBI-1055001|uniprotkb:Q6FGA1|uniprotkb:Q9NYM0|uniprotkb:Q9UCJ1|uniprotkb:D3DV36|ensembl:ENSP00000357727 psi-mi:pf21b_human(display_long)|uniprotkb:PHF21B(gene name)|psi-mi:PHF21B(display_short)|uniprotkb:KIAA1661(gene name synonym) psi-mi:s10a9_human(display_long)|uniprotkb:S100 calcium-binding protein A9(gene name synonym)|uniprotkb:Calgranulin-B(gene name synonym)|uniprotkb:Migration inhibitory factor-related protein 14(gene name synonym)|uniprotkb:Leukocyte L1 complex heavy chain(gene name synonym)|uniprotkb:Calprotectin L1H subunit(gene name synonym)|uniprotkb:S100A9(gene name)|psi-mi:S100A9(display_short)|uniprotkb:CAGB(gene name synonym)|uniprotkb:CFAG(gene name synonym)|uniprotkb:MRP14(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482406|imex:IM-26985-419 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000056487(gene)|ensembl:ENST00000313237(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|mint:Q96EK2|refseq:NP_001129334.1|refseq:NP_001229379.1|refseq:NP_001271225.1|refseq:NP_612424.1|refseq:XP_006724185.1 refseq:NP_002956.1|rcsb pdb:1XK4|rcsb pdb:4GGF|rcsb pdb:4XJK|rcsb pdb:5I8N|rcsb pdb:5W1F|rcsb pdb:6DS2|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5668599|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-6799990|ensembl:ENSG00000163220(gene)|ensembl:ENST00000368738(transcript)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035662"(Toll-like receptor 4 binding)|go:"GO:0035821"(modulation of process of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0045113"(regulation of integrin biosynthetic process)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070488"(neutrophil aggregation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|mint:P06702|rcsb pdb:1IRJ|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016209"(antioxidant activity)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0030054"(cell junction)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032119"(sequestering of zinc ion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035425"(autocrine signaling)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|dip:DIP-1166N - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FhssIBtwxKIFiyGylNLhTTFcyrI9606 rogid:IGnX4DSnv8xMr5pY4T7X7vYos5A9606 rigid:7NjI4eHLAdqggBuMeiILRJUlWBI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96EK2 uniprotkb:P05164 intact:EBI-16472119|ensembl:ENSP00000324403|uniprotkb:B0QYW3|uniprotkb:B0QYW4|uniprotkb:B3KRU4|uniprotkb:B7Z4F8|uniprotkb:Q5TFL2|uniprotkb:Q6ICC0 intact:EBI-2556173|uniprotkb:Q14862|uniprotkb:Q9UCL7|uniprotkb:A1L4B8|uniprotkb:Q4PJH5|ensembl:ENSP00000225275 psi-mi:pf21b_human(display_long)|uniprotkb:PHF21B(gene name)|psi-mi:PHF21B(display_short)|uniprotkb:KIAA1661(gene name synonym) psi-mi:perm_human(display_long)|uniprotkb:MPO(gene name)|psi-mi:MPO(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482406|imex:IM-26985-419 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000056487(gene)|ensembl:ENST00000313237(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|mint:Q96EK2|refseq:NP_001129334.1|refseq:NP_001229379.1|refseq:NP_001271225.1|refseq:NP_612424.1|refseq:XP_006724185.1 refseq:NP_000241.1|ensembl:ENSG00000005381(gene)|go:"GO:0002149"(hypochlorous acid biosynthetic process)|go:"GO:0002679"(respiratory burst involved in defense response)|go:"GO:0003682"(chromatin binding)|ensembl:ENST00000225275(transcript)|go:"GO:0001878"(response to yeast)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0006952"(defense response)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007568"(aging)|go:"GO:0008201"(heparin binding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0020037"(heme binding)|go:"GO:0030141"(secretory granule)|go:"GO:0032094"(response to food)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034374"(low-density lipoprotein particle remodeling)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042582"(azurophil granule)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|go:"GO:0050832"(defense response to fungus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1990268"(response to gold nanoparticle)|interpro:IPR010255(Haem peroxidase)|interpro:IPR019791|interpro:IPR029609|interpro:IPR037120|mint:P05164|rcsb pdb:1CXP|rcsb pdb:1D2V|rcsb pdb:1D5L|rcsb pdb:1D7W|rcsb pdb:1DNU|rcsb pdb:1DNW|rcsb pdb:1MHL|rcsb pdb:1MYP|rcsb pdb:3F9P|rcsb pdb:3ZS0|rcsb pdb:3ZS1|rcsb pdb:4C1M|rcsb pdb:4DL1|rcsb pdb:4EJX|rcsb pdb:5FIW|rcsb pdb:5MFA|rcsb pdb:5UZU|rcsb pdb:6AZP|rcsb pdb:6BMT|reactome:R-HSA-6798695|reactome:R-HSA-8941413 - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FhssIBtwxKIFiyGylNLhTTFcyrI9606 rogid:SNoAXb3csr/iOyGWeyWcUyJTZLY9606 rigid:7NjI4eHLAdqggBuMeiILRJUlWBI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96EK2 uniprotkb:Q92769 intact:EBI-16472119|ensembl:ENSP00000324403|uniprotkb:B0QYW3|uniprotkb:B0QYW4|uniprotkb:B3KRU4|uniprotkb:B7Z4F8|uniprotkb:Q5TFL2|uniprotkb:Q6ICC0 intact:EBI-301821|uniprotkb:Q5SRI8|uniprotkb:Q5SZ86|uniprotkb:Q8NEH4|uniprotkb:B4DL58|ensembl:ENSP00000430432|uniprotkb:E1P561|uniprotkb:B3KRS5 psi-mi:pf21b_human(display_long)|uniprotkb:PHF21B(gene name)|psi-mi:PHF21B(display_short)|uniprotkb:KIAA1661(gene name synonym) psi-mi:hdac2_human(display_long)|uniprotkb:HDAC2(gene name)|psi-mi:HDAC2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482406|imex:IM-26985-419 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000056487(gene)|ensembl:ENST00000313237(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|mint:Q96EK2|refseq:NP_001129334.1|refseq:NP_001229379.1|refseq:NP_001271225.1|refseq:NP_612424.1|refseq:XP_006724185.1 go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035094"(response to nicotine)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042220"(response to cocaine)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q92769|rcsb pdb:3MAX|rcsb pdb:4LXZ|rcsb pdb:4LY1|rcsb pdb:5IWG|rcsb pdb:5IX0|rcsb pdb:6G3O|rcsb pdb:6WBW|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|ensembl:ENSG00000196591(gene)|ensembl:ENST00000519065(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|rcsb pdb:6WHN|rcsb pdb:6WHO|rcsb pdb:6WHQ|rcsb pdb:6WHZ|rcsb pdb:6WI3|rcsb pdb:6XDM|rcsb pdb:6XEB|rcsb pdb:6XEC|rcsb pdb:7KBG|rcsb pdb:7KBH|rcsb pdb:7LTG|rcsb pdb:7LTK|rcsb pdb:7LTL|reactome:R-HSA-193670|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9615017|reactome:R-HSA-9619665|reactome:R-HSA-9679191|reactome:R-HSA-983231|rcsb pdb:6WBZ|refseq:NP_001518.3|dip:DIP-24220N|refseq:XP_011534090.1|refseq:XP_016866288.1 - - comment:"author score: 36" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FhssIBtwxKIFiyGylNLhTTFcyrI9606 rogid:K4PpGz9E9/TrQZsgvrJuc+uYCn89606 rigid:7NjI4eHLAdqggBuMeiILRJUlWBI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96EK2 uniprotkb:P02788 intact:EBI-16472119|ensembl:ENSP00000324403|uniprotkb:B0QYW3|uniprotkb:B0QYW4|uniprotkb:B3KRU4|uniprotkb:B7Z4F8|uniprotkb:Q5TFL2|uniprotkb:Q6ICC0 intact:EBI-1058602|ensembl:ENSP00000231751|uniprotkb:O00756|uniprotkb:Q16780|uniprotkb:Q16785|uniprotkb:Q16786|uniprotkb:Q16789|uniprotkb:Q8IU92|uniprotkb:Q8IZH6|uniprotkb:Q8TCD2|uniprotkb:Q96KZ4|uniprotkb:Q96KZ5|uniprotkb:Q9H1Z3|uniprotkb:Q9UCY5|uniprotkb:B7Z4X2|uniprotkb:E7EQH5|uniprotkb:B2MV13|uniprotkb:Q5DSM0|uniprotkb:A8K9U8 psi-mi:pf21b_human(display_long)|uniprotkb:PHF21B(gene name)|psi-mi:PHF21B(display_short)|uniprotkb:KIAA1661(gene name synonym) psi-mi:trfl_human(display_long)|uniprotkb:LTF(gene name)|psi-mi:LTF(display_short)|uniprotkb:LF(gene name synonym)|uniprotkb:Talalactoferrin(gene name synonym)|uniprotkb:GIG12(gene name synonym)|uniprotkb:Growth-inhibiting protein 12(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482406|imex:IM-26985-419 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000056487(gene)|ensembl:ENST00000313237(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|mint:Q96EK2|refseq:NP_001129334.1|refseq:NP_001229379.1|refseq:NP_001271225.1|refseq:NP_612424.1|refseq:XP_006724185.1 refseq:NP_001308050.1|ensembl:ENST00000231751(transcript)|go:"GO:0001503"(ossification)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0001895"(retina homeostasis)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006826"(iron ion transport)|go:"GO:0006959"(humoral immune response)|go:"GO:0008201"(heparin binding)|ensembl:ENSG00000012223(gene)|refseq:NP_001186078.1|refseq:NP_002334.2|go:"GO:0009986"(cell surface)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0019732"(antifungal humoral response)|go:"GO:0030141"(secretory granule)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0031665"(negative regulation of lipopolysaccharide-mediated signaling pathway)|go:"GO:0032680"(regulation of tumor necrosis factor production)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0055037"(recycling endosome)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0060349"(bone morphogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033690"(positive regulation of osteoblast proliferation)|go:"GO:0034145"(positive regulation of toll-like receptor 4 signaling pathway)|go:"GO:0035580"(specific granule lumen)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097013"(phagocytic vesicle lumen)|go:"GO:1900159"(positive regulation of bone mineralization involved in bone maturation)|go:"GO:1900229"(negative regulation of single-species biofilm formation in or on host organism)|go:"GO:0042581"(specific granule)|go:"GO:1902732"(positive regulation of chondrocyte proliferation)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:2000117"(negative regulation of cysteine-type endopeptidase activity)|go:"GO:2000308"("negative regulation of tumor necrosis factor (ligand) superfamily member 11 production")|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:2001205"(negative regulation of osteoclast development)|go:"GO:0044793"(negative regulation by host of viral process)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|interpro:IPR001156(Peptidase S60, transferrin lactoferrin)|go:"GO:0045837"(negative regulation of membrane potential)|go:"GO:0048525"(negative regulation of viral process)|interpro:IPR016357(Transferrin)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051673"(membrane disruption in another organism)|interpro:IPR018195|interpro:IPR030684|mint:P02788|rcsb pdb:1B0L|rcsb pdb:1BKA|rcsb pdb:1CB6|rcsb pdb:1DSN|rcsb pdb:1EH3|rcsb pdb:1FCK|rcsb pdb:1H43|rcsb pdb:1H44|rcsb pdb:1H45|rcsb pdb:1HSE|rcsb pdb:1L5T|rcsb pdb:1LCF|rcsb pdb:1LCT|rcsb pdb:1LFG|rcsb pdb:1LFH|rcsb pdb:1LFI|rcsb pdb:1LGB|rcsb pdb:1N76|rcsb pdb:1SQY|rcsb pdb:1VFD|rcsb pdb:1VFE|rcsb pdb:1XV4|rcsb pdb:1XV7|rcsb pdb:1Z6V|rcsb pdb:1Z6W|rcsb pdb:2BJJ|rcsb pdb:2DP4|rcsb pdb:2GMC|rcsb pdb:2GMD|rcsb pdb:2HD4|rcsb pdb:2PMS|reactome:R-HSA-1222449|reactome:R-HSA-6798695|reactome:R-HSA-6799990|reactome:R-HSA-6803157|reactome:R-HSA-977225|rcsb pdb:1U62|refseq:NP_001308051.1|dip:DIP-41354N - - comment:"author score: 44" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FhssIBtwxKIFiyGylNLhTTFcyrI9606 rogid:OLhbdYXPaD10eAg3HyhCA5Akw8o9606 rigid:7NjI4eHLAdqggBuMeiILRJUlWBI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96EK2 uniprotkb:Q86YI8 intact:EBI-16472119|ensembl:ENSP00000324403|uniprotkb:B0QYW3|uniprotkb:B0QYW4|uniprotkb:B3KRU4|uniprotkb:B7Z4F8|uniprotkb:Q5TFL2|uniprotkb:Q6ICC0 intact:EBI-3925468|uniprotkb:Q9UJP2|uniprotkb:Q59FB6|uniprotkb:Q5TH65|uniprotkb:Q8N551|uniprotkb:B3KUQ7|ensembl:ENSP00000366876 psi-mi:pf21b_human(display_long)|uniprotkb:PHF21B(gene name)|psi-mi:PHF21B(display_short)|uniprotkb:KIAA1661(gene name synonym) psi-mi:phf13_human(display_long)|uniprotkb:PHF13(gene name)|psi-mi:PHF13(display_short)|uniprotkb:Survival time-associated PHD finger protein in ovarian cancer 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482406|imex:IM-26985-419 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000056487(gene)|ensembl:ENST00000313237(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|mint:Q96EK2|refseq:NP_001129334.1|refseq:NP_001229379.1|refseq:NP_001271225.1|refseq:NP_612424.1|refseq:XP_006724185.1 refseq:NP_722519.2|ensembl:ENSG00000116273(gene)|ensembl:ENST00000377648(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR041947|mint:Q86YI8|rcsb pdb:3O70|rcsb pdb:3O7A - - comment:"author score: 53" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FhssIBtwxKIFiyGylNLhTTFcyrI9606 rogid:srKPJn9CZJxhg8kNezGDdiz1GDw9606 rigid:7NjI4eHLAdqggBuMeiILRJUlWBI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96EK2 uniprotkb:Q9P2K3 intact:EBI-16472119|ensembl:ENSP00000324403|uniprotkb:B0QYW3|uniprotkb:B0QYW4|uniprotkb:B3KRU4|uniprotkb:B7Z4F8|uniprotkb:Q5TFL2|uniprotkb:Q6ICC0 intact:EBI-743428|uniprotkb:B3KYA2|uniprotkb:B4DYY7|uniprotkb:Q5VT47|uniprotkb:Q7L9I5|uniprotkb:Q8N5U3|uniprotkb:Q9NV83|ensembl:ENSP00000355972 psi-mi:pf21b_human(display_long)|uniprotkb:PHF21B(gene name)|psi-mi:PHF21B(display_short)|uniprotkb:KIAA1661(gene name synonym) psi-mi:rcor3_human(display_long)|uniprotkb:RCOR3(gene name)|psi-mi:RCOR3(display_short)|uniprotkb:KIAA1343(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482406|imex:IM-26985-419 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000056487(gene)|ensembl:ENST00000313237(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|mint:Q96EK2|refseq:NP_001129334.1|refseq:NP_001229379.1|refseq:NP_001271225.1|refseq:NP_612424.1|refseq:XP_006724185.1 rcsb pdb:4CZZ|refseq:NP_001129695.1|refseq:NP_001129696.2|refseq:NP_001129697.1|refseq:NP_060724.1|ensembl:ENSG00000117625(gene)|ensembl:ENST00000367005(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016575"(histone deacetylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|mint:Q9P2K3 - - comment:"author score: 57" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FhssIBtwxKIFiyGylNLhTTFcyrI9606 rogid:hzuKCK7o/85XbN65z8Ua+XNaSJc9606 rigid:7NjI4eHLAdqggBuMeiILRJUlWBI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96EK2 uniprotkb:Q9UKL0 intact:EBI-16472119|ensembl:ENSP00000324403|uniprotkb:B0QYW3|uniprotkb:B0QYW4|uniprotkb:B3KRU4|uniprotkb:B7Z4F8|uniprotkb:Q5TFL2|uniprotkb:Q6ICC0 intact:EBI-926563|uniprotkb:Q15044|uniprotkb:Q6P2I9|uniprotkb:Q86VG5|intact:EBI-11087913|uniprotkb:J3KN32|ensembl:ENSP00000262241 psi-mi:pf21b_human(display_long)|uniprotkb:PHF21B(gene name)|psi-mi:PHF21B(display_short)|uniprotkb:KIAA1661(gene name synonym) psi-mi:rcor1_human(display_long)|uniprotkb:RCOR1(gene name)|psi-mi:RCOR1(display_short)|uniprotkb:KIAA0071(gene name synonym)|uniprotkb:RCOR(gene name synonym)|uniprotkb:Protein CoREST(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482406|imex:IM-26985-419 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000056487(gene)|ensembl:ENST00000313237(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|mint:Q96EK2|refseq:NP_001129334.1|refseq:NP_001229379.1|refseq:NP_001271225.1|refseq:NP_612424.1|refseq:XP_006724185.1 refseq:NP_055971.2|dip:DIP-35263N|ensembl:ENSG00000089902(gene)|ensembl:ENST00000262241(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0045654"(positive regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:1990391"(DNA repair complex)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|mint:Q9UKL0|rcsb pdb:2IW5|rcsb pdb:2UXN|rcsb pdb:2UXX|rcsb pdb:2V1D|rcsb pdb:2X0L|rcsb pdb:2XAF|rcsb pdb:2XAG|rcsb pdb:2XAH|rcsb pdb:2XAJ|rcsb pdb:2XAQ|rcsb pdb:2XAS|rcsb pdb:2Y48|rcsb pdb:3ZMS|rcsb pdb:3ZMT|rcsb pdb:3ZMU|rcsb pdb:3ZMV|rcsb pdb:3ZMZ|rcsb pdb:3ZN0|rcsb pdb:3ZN1|rcsb pdb:4BAY|rcsb pdb:4KUM|rcsb pdb:4UV8|rcsb pdb:4UV9|rcsb pdb:4UVA|rcsb pdb:4UVB|rcsb pdb:4UVC|rcsb pdb:4UXN|rcsb pdb:4XBF|rcsb pdb:5H6Q|rcsb pdb:5H6R|rcsb pdb:5L3B|rcsb pdb:5L3C|rcsb pdb:5L3D|rcsb pdb:5L3E|rcsb pdb:5L3F|rcsb pdb:5L3G|rcsb pdb:5LBQ|rcsb pdb:5LGN|rcsb pdb:5LGT|rcsb pdb:5LGU|rcsb pdb:5LHG|rcsb pdb:5LHH|rcsb pdb:5LHI|rcsb pdb:5X60|rcsb pdb:5YJB|rcsb pdb:6K3E|rcsb pdb:6KGK|rcsb pdb:6KGL|rcsb pdb:6KGM|rcsb pdb:6KGN|rcsb pdb:6S35|rcsb pdb:6TE1|rcsb pdb:6VYP|rcsb pdb:6W4K|rcsb pdb:6WC6|rcsb pdb:7CDC|rcsb pdb:7CDD|rcsb pdb:7CDE|rcsb pdb:7CDF|rcsb pdb:7CDG|reactome:R-HSA-3214815|reactome:R-HSA-8943724|reactome:R-HSA-9679191|reactome:R-HSA-983231 - - comment:"author score: 72" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FhssIBtwxKIFiyGylNLhTTFcyrI9606 rogid:B1KfnjicGzKdWGnGGrZwjgpMQ309606 rigid:7NjI4eHLAdqggBuMeiILRJUlWBI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96EK2 uniprotkb:O60341 intact:EBI-16472119|ensembl:ENSP00000324403|uniprotkb:B0QYW3|uniprotkb:B0QYW4|uniprotkb:B3KRU4|uniprotkb:B7Z4F8|uniprotkb:Q5TFL2|uniprotkb:Q6ICC0 intact:EBI-710124|uniprotkb:Q5TH94|uniprotkb:Q5TH95|uniprotkb:Q86VT7|uniprotkb:Q8IXK4|uniprotkb:Q8NDP6|uniprotkb:Q8TAZ3|uniprotkb:Q96AW4|ensembl:ENSP00000349049|uniprotkb:A8MWP9 psi-mi:pf21b_human(display_long)|uniprotkb:PHF21B(gene name)|psi-mi:PHF21B(display_short)|uniprotkb:KIAA1661(gene name synonym) psi-mi:kdm1a_human(display_long)|uniprotkb:Flavin-containing amine oxidase domain-containing protein 2(gene name synonym)|uniprotkb:BRAF35-HDAC complex protein BHC110(gene name synonym)|uniprotkb:KDM1A(gene name)|psi-mi:KDM1A(display_short)|uniprotkb:KIAA0601(gene name synonym)|uniprotkb:LSD1(gene name synonym)|uniprotkb:AOF2(gene name synonym)|uniprotkb:KDM1(gene name synonym)|uniprotkb:"[histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A"(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482406|imex:IM-26985-419 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000056487(gene)|ensembl:ENST00000313237(transcript)|go:"GO:0046872"(metal ion binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|mint:Q96EK2|refseq:NP_001129334.1|refseq:NP_001229379.1|refseq:NP_001271225.1|refseq:NP_612424.1|refseq:XP_006724185.1 go:"GO:0021987"(cerebral cortex development)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032451"(demethylase activity)|refseq:NP_001009999.1|refseq:NP_055828.2|ensembl:ENSG00000004487(gene)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|ensembl:ENST00000356634(transcript)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|dip:DIP-34641N|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0033184"(positive regulation of histone ubiquitination)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042551"(neuron maturation)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043426"(MRF binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046098"(guanine metabolic process)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0060992"(response to fungicide)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061752"(telomeric repeat-containing RNA binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1903827"|go:"GO:1990391"(DNA repair complex)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2000648"(positive regulation of stem cell proliferation)|interpro:IPR002937(Amine oxidase)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017366(Histone lysine-specific demethylase)|interpro:IPR036188|interpro:IPR036388|mint:O60341|rcsb pdb:2COM|rcsb pdb:2DW4|rcsb pdb:2EJR|rcsb pdb:2H94|rcsb pdb:2HKO|rcsb pdb:2IW5|rcsb pdb:2L3D|rcsb pdb:2UXN|rcsb pdb:2UXX|rcsb pdb:2V1D|rcsb pdb:2X0L|rcsb pdb:2XAF|rcsb pdb:2XAG|rcsb pdb:2XAH|rcsb pdb:2XAJ|rcsb pdb:2XAQ|rcsb pdb:2XAS|rcsb pdb:2Y48|rcsb pdb:2Z3Y|rcsb pdb:2Z5U|rcsb pdb:3ABT|rcsb pdb:3ABU|rcsb pdb:3ZMS|rcsb pdb:3ZMT|rcsb pdb:3ZMU|rcsb pdb:3ZMV|rcsb pdb:3ZMZ|rcsb pdb:3ZN0|rcsb pdb:3ZN1|rcsb pdb:4BAY|rcsb pdb:4CZZ|rcsb pdb:4KUM|rcsb pdb:4UV8|rcsb pdb:4UV9|rcsb pdb:4UVA|rcsb pdb:4UVB|rcsb pdb:4UVC|rcsb pdb:4UXN|rcsb pdb:4XBF|rcsb pdb:5AFW|rcsb pdb:5H6Q|rcsb pdb:5H6R|rcsb pdb:5IT3|rcsb pdb:5L3B|rcsb pdb:5L3C|rcsb pdb:5L3D|rcsb pdb:5L3E|rcsb pdb:5L3F|rcsb pdb:5L3G|rcsb pdb:5LBQ|rcsb pdb:5LGN|rcsb pdb:5LGT|rcsb pdb:5LGU|rcsb pdb:5LHG|rcsb pdb:5LHH|rcsb pdb:5LHI|rcsb pdb:5X60|rcsb pdb:5YJB|rcsb pdb:6E1F|rcsb pdb:6K3E|rcsb pdb:6KGK|rcsb pdb:6KGL|rcsb pdb:6KGM|rcsb pdb:6KGN|rcsb pdb:6KGO|rcsb pdb:6KGP|rcsb pdb:6KGQ|rcsb pdb:6KGR|rcsb pdb:6NQM|rcsb pdb:6NQU|rcsb pdb:6NR5|rcsb pdb:6S35|rcsb pdb:6TE1|rcsb pdb:6VYP|rcsb pdb:6W4K|rcsb pdb:6WC6|rcsb pdb:7CDC|rcsb pdb:7CDD|rcsb pdb:7CDE|rcsb pdb:7CDF|rcsb pdb:7CDG|rcsb pdb:7E0G|rcsb pdb:7JJL|rcsb pdb:7JJM|rcsb pdb:7JK7|reactome:R-HSA-3214815|reactome:R-HSA-3214842|reactome:R-HSA-5625886|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9029569|reactome:R-HSA-9679191|reactome:R-HSA-983231 - - comment:"author score: 85" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FhssIBtwxKIFiyGylNLhTTFcyrI9606 rogid:rS9F23Rg1Ha6XOQSisWQfhKVFfs9606 rigid:7NjI4eHLAdqggBuMeiILRJUlWBI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IE81 uniprotkb:Q9H6Z4 intact:EBI-954672|uniprotkb:Q4W5D5|uniprotkb:Q6ZSL7|uniprotkb:Q8NC41|uniprotkb:Q96JL8|uniprotkb:Q96SQ1|uniprotkb:Q9H692|uniprotkb:D3DNY0|uniprotkb:D3DNY1|ensembl:ENSP00000226319|ensembl:ENSP00000425730|ensembl:ENSP00000482212|ensembl:ENSP00000483219 intact:EBI-992681|uniprotkb:O60405|uniprotkb:O75759|uniprotkb:O75760|uniprotkb:Q9BT47|uniprotkb:Q9UG74|uniprotkb:B2RAT8|intact:EBI-28977370|ensembl:ENSP00000341483 psi-mi:jade1_human(display_long)|uniprotkb:JADE1(gene name)|psi-mi:JADE1(display_short)|uniprotkb:Jade family PHD finger protein 1(gene name synonym)|uniprotkb:KIAA1807(gene name synonym)|uniprotkb:PHD finger protein 17(gene name synonym)|uniprotkb:PHF17(gene name synonym) psi-mi:ranb3_human(display_long)|uniprotkb:RANBP3(gene name)|psi-mi:RANBP3(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482337|imex:IM-26985-341 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079176.2|refseq:NP_955352.1|refseq:NP_001274372.1|refseq:NP_001274366.1|refseq:NP_001274368.1|refseq:NP_001274369.1|refseq:NP_001274370.1|refseq:NP_001274371.1|ensembl:ENSG00000077684(gene)|ensembl:ENST00000226319(transcript)|ensembl:ENST00000512960(transcript)|ensembl:ENST00000610919(transcript)|ensembl:ENST00000611140(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR039546|mint:Q6IE81|reactome:R-HSA-3214847|refseq:XP_005263289.1 ensembl:ENSG00000031823(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0031267"(small GTPase binding)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070412"(R-SMAD binding)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR011993(Pleckstrin homology-type)|mint:Q9H6Z4|rcsb pdb:2CRF|rcsb pdb:2Y8F|rcsb pdb:2Y8G|rcsb pdb:5XZX|ensembl:ENST00000340578(transcript)|ensembl:ENST00000034275|ensembl:ENSP00000034275|ensembl:ENSP00000341483|ensembl:ENST00000439268|ensembl:ENSP00000404837|refseq:NP_001287794.1|refseq:NP_003615.2|refseq:NP_015559.2|refseq:NP_015561.1 - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:brla9icZHYnZBj+2WtExolD2Z489606 rogid:6yarcNQk5YtZzq6Pq9e9aBGjBO09606 rigid:SBtv0PJkCBV4y4DOwAbMsoBx26A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IE81 uniprotkb:P09211 intact:EBI-954672|uniprotkb:Q4W5D5|uniprotkb:Q6ZSL7|uniprotkb:Q8NC41|uniprotkb:Q96JL8|uniprotkb:Q96SQ1|uniprotkb:Q9H692|uniprotkb:D3DNY0|uniprotkb:D3DNY1|ensembl:ENSP00000226319|ensembl:ENSP00000425730|ensembl:ENSP00000482212|ensembl:ENSP00000483219 intact:EBI-353467|uniprotkb:O00460|uniprotkb:Q15690|ensembl:ENSP00000381607|uniprotkb:Q5TZY3 psi-mi:jade1_human(display_long)|uniprotkb:JADE1(gene name)|psi-mi:JADE1(display_short)|uniprotkb:Jade family PHD finger protein 1(gene name synonym)|uniprotkb:KIAA1807(gene name synonym)|uniprotkb:PHD finger protein 17(gene name synonym)|uniprotkb:PHF17(gene name synonym) psi-mi:gstp1_human(display_long)|uniprotkb:GSTP1(gene name)|psi-mi:GSTP1(display_short)|uniprotkb:GST3(gene name synonym)|uniprotkb:FAEES3(gene name synonym)|uniprotkb:GST class-pi(gene name synonym)|uniprotkb:GSTP1-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482337|imex:IM-26985-341 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079176.2|refseq:NP_955352.1|refseq:NP_001274372.1|refseq:NP_001274366.1|refseq:NP_001274368.1|refseq:NP_001274369.1|refseq:NP_001274370.1|refseq:NP_001274371.1|ensembl:ENSG00000077684(gene)|ensembl:ENST00000226319(transcript)|ensembl:ENST00000512960(transcript)|ensembl:ENST00000610919(transcript)|ensembl:ENST00000611140(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR039546|mint:Q6IE81|reactome:R-HSA-3214847|refseq:XP_005263289.1 refseq:NP_000843.1|ensembl:ENSG00000084207(gene)|go:"GO:0000302"(response to reactive oxygen species)|ensembl:ENST00000398606(transcript)|go:"GO:0002674"(negative regulation of acute inflammatory response)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006693"(prostaglandin metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0009890"(negative regulation of biosynthetic process)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0014003"(oligodendrocyte development)|go:"GO:0019207"(kinase regulator activity)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031982"(vesicle)|go:"GO:0032355"(response to estradiol)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0033591"(response to L-ascorbic acid)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035726"(common myeloid progenitor cell proliferation)|go:"GO:0035730"(S-nitrosoglutathione binding)|go:"GO:0035731"(dinitrosyl-iron complex binding)|go:"GO:0035732"(nitric oxide storage)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0043651"(linoleic acid metabolic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0051122"(hepoxilin biosynthetic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003082(Glutathione S-transferase, Pi class)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR040079|mint:P09211|rcsb pdb:10GS|rcsb pdb:11GS|rcsb pdb:12GS|rcsb pdb:13GS|rcsb pdb:14GS|rcsb pdb:16GS|rcsb pdb:17GS|rcsb pdb:18GS|rcsb pdb:19GS|rcsb pdb:1AQV|rcsb pdb:1AQW|rcsb pdb:1AQX|rcsb pdb:1EOG|rcsb pdb:1EOH|rcsb pdb:1GSS|rcsb pdb:1KBN|rcsb pdb:1LBK|rcsb pdb:1MD3|rcsb pdb:1MD4|rcsb pdb:1PGT|rcsb pdb:1PX6|rcsb pdb:1PX7|rcsb pdb:1ZGN|rcsb pdb:20GS|rcsb pdb:22GS|rcsb pdb:2A2R|rcsb pdb:2A2S|rcsb pdb:2GSS|rcsb pdb:2J9H|rcsb pdb:2PGT|rcsb pdb:3CSH|rcsb pdb:3CSI|rcsb pdb:3CSJ|rcsb pdb:3DD3|rcsb pdb:3DGQ|rcsb pdb:3GSS|rcsb pdb:3GUS|rcsb pdb:3HJM|rcsb pdb:3HJO|rcsb pdb:3HKR|rcsb pdb:3IE3|rcsb pdb:3KM6|rcsb pdb:3KMN|rcsb pdb:3KMO|rcsb pdb:3N9J|rcsb pdb:3PGT|rcsb pdb:4GSS|rcsb pdb:4PGT|rcsb pdb:5DAK|rcsb pdb:5DAL|rcsb pdb:5DCG|rcsb pdb:5DDL|rcsb pdb:5DJL|rcsb pdb:5DJM|rcsb pdb:5GSS|rcsb pdb:5J41|rcsb pdb:5JCW|rcsb pdb:5L6X|rcsb pdb:5X79|rcsb pdb:6AP9|rcsb pdb:6GSS|rcsb pdb:6LLX|rcsb pdb:6Y1E|rcsb pdb:7GSS|rcsb pdb:8GSS|rcsb pdb:9GSS|reactome:R-HSA-156590|reactome:R-HSA-3299685|reactome:R-HSA-6798695|go:"GO:0051771"(negative regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0070026"(nitric oxide binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070664"(negative regulation of leukocyte proliferation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071460"(cellular response to cell-matrix adhesion)|go:"GO:0071638"(negative regulation of monocyte chemotactic protein-1 production)|go:"GO:0071672"(negative regulation of smooth muscle cell chemotaxis)|go:"GO:0097057"(TRAF2-GSTP1 complex)|go:"GO:1901687"(glutathione derivative biosynthetic process)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation) - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:brla9icZHYnZBj+2WtExolD2Z489606 rogid:JxqbNusNIvkTg3Cq+7pmygP/EIA9606 rigid:SBtv0PJkCBV4y4DOwAbMsoBx26A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IE81 uniprotkb:Q7L2J0 intact:EBI-954672|uniprotkb:Q4W5D5|uniprotkb:Q6ZSL7|uniprotkb:Q8NC41|uniprotkb:Q96JL8|uniprotkb:Q96SQ1|uniprotkb:Q9H692|uniprotkb:D3DNY0|uniprotkb:D3DNY1|ensembl:ENSP00000226319|ensembl:ENSP00000425730|ensembl:ENSP00000482212|ensembl:ENSP00000483219 intact:EBI-2371983|uniprotkb:Q9NPD4|uniprotkb:B3KP86|uniprotkb:D6W5V7|ensembl:ENSP00000308546 psi-mi:jade1_human(display_long)|uniprotkb:JADE1(gene name)|psi-mi:JADE1(display_short)|uniprotkb:Jade family PHD finger protein 1(gene name synonym)|uniprotkb:KIAA1807(gene name synonym)|uniprotkb:PHD finger protein 17(gene name synonym)|uniprotkb:PHF17(gene name synonym) psi-mi:mepce_human(display_long)|uniprotkb:MEPCE(gene name)|psi-mi:MEPCE(display_short)|uniprotkb:BCDIN3(gene name synonym)|uniprotkb:Bicoid-interacting protein 3 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482337|imex:IM-26985-341 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079176.2|refseq:NP_955352.1|refseq:NP_001274372.1|refseq:NP_001274366.1|refseq:NP_001274368.1|refseq:NP_001274369.1|refseq:NP_001274370.1|refseq:NP_001274371.1|ensembl:ENSG00000077684(gene)|ensembl:ENST00000226319(transcript)|ensembl:ENST00000512960(transcript)|ensembl:ENST00000610919(transcript)|ensembl:ENST00000611140(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR039546|mint:Q6IE81|reactome:R-HSA-3214847|refseq:XP_005263289.1 refseq:XP_011514712.1|refseq:NP_001181919.1|refseq:NP_001181920.1|refseq:NP_001181921.1|refseq:NP_062552.2|ensembl:ENSG00000146834(gene)|ensembl:ENST00000310512(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001510"(RNA methylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0008171"(O-methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0016073"(snRNA metabolic process)|go:"GO:0017069"(snRNA binding)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0040031"(snRNA modification)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1905382"(positive regulation of snRNA transcription by RNA polymerase II)|go:"GO:1990276"(RNA 5'-methyltransferase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR010675(Bicoid-interacting 3)|interpro:IPR024160|interpro:IPR025714|interpro:IPR029063|interpro:IPR039772|mint:Q7L2J0|rcsb pdb:5UNA|rcsb pdb:6DCB|rcsb pdb:6DCC - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:brla9icZHYnZBj+2WtExolD2Z489606 rogid:VGhJoO3FD7nsJPVSBsKuKsPJzEM9606 rigid:SBtv0PJkCBV4y4DOwAbMsoBx26A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IE81 uniprotkb:P62750 intact:EBI-954672|uniprotkb:Q4W5D5|uniprotkb:Q6ZSL7|uniprotkb:Q8NC41|uniprotkb:Q96JL8|uniprotkb:Q96SQ1|uniprotkb:Q9H692|uniprotkb:D3DNY0|uniprotkb:D3DNY1|ensembl:ENSP00000226319|ensembl:ENSP00000425730|ensembl:ENSP00000482212|ensembl:ENSP00000483219 intact:EBI-353254|uniprotkb:P29316|uniprotkb:Q92774|uniprotkb:P39024|uniprotkb:B2R5B2|ensembl:ENSP00000389103 psi-mi:jade1_human(display_long)|uniprotkb:JADE1(gene name)|psi-mi:JADE1(display_short)|uniprotkb:Jade family PHD finger protein 1(gene name synonym)|uniprotkb:KIAA1807(gene name synonym)|uniprotkb:PHD finger protein 17(gene name synonym)|uniprotkb:PHF17(gene name synonym) psi-mi:rl23a_human(display_long)|uniprotkb:RPL23A(gene name)|psi-mi:RPL23A(display_short)|uniprotkb:Large ribosomal subunit protein uL23(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482337|imex:IM-26985-341 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079176.2|refseq:NP_955352.1|refseq:NP_001274372.1|refseq:NP_001274366.1|refseq:NP_001274368.1|refseq:NP_001274369.1|refseq:NP_001274370.1|refseq:NP_001274371.1|ensembl:ENSG00000077684(gene)|ensembl:ENST00000226319(transcript)|ensembl:ENST00000512960(transcript)|ensembl:ENST00000610919(transcript)|ensembl:ENST00000611140(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR039546|mint:Q6IE81|reactome:R-HSA-3214847|refseq:XP_005263289.1 reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|refseq:NP_000975.2|ensembl:ENSG00000198242(gene)|ensembl:ENST00000422514(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904841"(TORC2 complex binding)|interpro:IPR001014(Ribosomal protein L23, conserved site)|interpro:IPR005633(Ribosomal protein L23/L25, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR013025(Ribosomal protein L25/L23)|interpro:IPR019985|mint:P62750|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:brla9icZHYnZBj+2WtExolD2Z489606 rogid:lA1ubRFO9/Tl54Z1dKUzoCKvpAo9606 rigid:SBtv0PJkCBV4y4DOwAbMsoBx26A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IE81 uniprotkb:P04792 intact:EBI-954672|uniprotkb:Q4W5D5|uniprotkb:Q6ZSL7|uniprotkb:Q8NC41|uniprotkb:Q96JL8|uniprotkb:Q96SQ1|uniprotkb:Q9H692|uniprotkb:D3DNY0|uniprotkb:D3DNY1|ensembl:ENSP00000226319|ensembl:ENSP00000425730|ensembl:ENSP00000482212|ensembl:ENSP00000483219 intact:EBI-352682|uniprotkb:Q6FI47|uniprotkb:Q96C20|uniprotkb:Q96EI7|uniprotkb:Q9UC34|uniprotkb:Q9UC35|uniprotkb:Q9UC36|uniprotkb:Q9UC31|ensembl:ENSP00000248553|uniprotkb:B2R4N8 psi-mi:jade1_human(display_long)|uniprotkb:JADE1(gene name)|psi-mi:JADE1(display_short)|uniprotkb:Jade family PHD finger protein 1(gene name synonym)|uniprotkb:KIAA1807(gene name synonym)|uniprotkb:PHD finger protein 17(gene name synonym)|uniprotkb:PHF17(gene name synonym) psi-mi:hspb1_human(display_long)|uniprotkb:HSPB1(gene name)|psi-mi:HSPB1(display_short)|uniprotkb:HSP27(gene name synonym)|uniprotkb:HSP28(gene name synonym)|uniprotkb:Heat shock 27 kDa protein(gene name synonym)|uniprotkb:Stress-responsive protein 27(gene name synonym)|uniprotkb:Estrogen-regulated 24 kDa protein(gene name synonym)|uniprotkb:28 kDa heat shock protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482337|imex:IM-26985-341 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079176.2|refseq:NP_955352.1|refseq:NP_001274372.1|refseq:NP_001274366.1|refseq:NP_001274368.1|refseq:NP_001274369.1|refseq:NP_001274370.1|refseq:NP_001274371.1|ensembl:ENSG00000077684(gene)|ensembl:ENST00000226319(transcript)|ensembl:ENST00000512960(transcript)|ensembl:ENST00000610919(transcript)|ensembl:ENST00000611140(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR039546|mint:Q6IE81|reactome:R-HSA-3214847|refseq:XP_005263289.1 refseq:NP_001531.1|ensembl:ENSG00000106211(gene)|ensembl:ENST00000248553(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0038033"(positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037876|mint:P04792|rcsb pdb:2N3J|rcsb pdb:3Q9P|rcsb pdb:3Q9Q|rcsb pdb:4MJH|rcsb pdb:6DV5|rcsb pdb:6GJH|reactome:R-HSA-4420097|reactome:R-HSA-450408|reactome:R-HSA-5687128|reactome:R-HSA-9009391|dip:DIP-412N - - crc64:1B4DC44A6F6606D5|comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:brla9icZHYnZBj+2WtExolD2Z489606 rogid:vrDXIdzP30aHSDLHOh2D4x54eJY9606 rigid:SBtv0PJkCBV4y4DOwAbMsoBx26A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IE81 uniprotkb:Q15517 intact:EBI-954672|uniprotkb:Q4W5D5|uniprotkb:Q6ZSL7|uniprotkb:Q8NC41|uniprotkb:Q96JL8|uniprotkb:Q96SQ1|uniprotkb:Q9H692|uniprotkb:D3DNY0|uniprotkb:D3DNY1|ensembl:ENSP00000226319|ensembl:ENSP00000425730|ensembl:ENSP00000482212|ensembl:ENSP00000483219 intact:EBI-953708|ensembl:ENSP00000259726|ensembl:ENSP00000388386|ensembl:ENSP00000392863|ensembl:ENSP00000399604|uniprotkb:Q9NRH4|uniprotkb:Q9NRH5|uniprotkb:Q9NRH6|uniprotkb:Q9NRH7|uniprotkb:Q9NRH8|uniprotkb:Q9UBH8|uniprotkb:Q9UIN6|uniprotkb:Q9UIN7|uniprotkb:Q9UIN8|uniprotkb:Q9UIN9|uniprotkb:Q9UIP0|uniprotkb:O43509|uniprotkb:Q5SQ85|uniprotkb:Q5STD2|uniprotkb:Q7LA70|uniprotkb:Q7LA71|uniprotkb:Q86Z04|uniprotkb:Q8IZU4|uniprotkb:Q8IZU5|uniprotkb:Q8IZU6|uniprotkb:Q8N5P3|uniprotkb:Q95IF9|uniprotkb:Q9NP52|uniprotkb:Q9NPE0|uniprotkb:Q9NPG5|uniprotkb:B0S7V2|uniprotkb:B0UYZ7 psi-mi:jade1_human(display_long)|uniprotkb:JADE1(gene name)|psi-mi:JADE1(display_short)|uniprotkb:Jade family PHD finger protein 1(gene name synonym)|uniprotkb:KIAA1807(gene name synonym)|uniprotkb:PHD finger protein 17(gene name synonym)|uniprotkb:PHF17(gene name synonym) psi-mi:cdsn_human(display_long)|uniprotkb:CDSN(gene name)|psi-mi:CDSN(display_short)|uniprotkb:S protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482337|imex:IM-26985-341 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079176.2|refseq:NP_955352.1|refseq:NP_001274372.1|refseq:NP_001274366.1|refseq:NP_001274368.1|refseq:NP_001274369.1|refseq:NP_001274370.1|refseq:NP_001274371.1|ensembl:ENSG00000077684(gene)|ensembl:ENST00000226319(transcript)|ensembl:ENST00000512960(transcript)|ensembl:ENST00000610919(transcript)|ensembl:ENST00000611140(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR039546|mint:Q6IE81|reactome:R-HSA-3214847|refseq:XP_005263289.1 ensembl:ENSG00000137197(gene)|ensembl:ENSG00000237114(gene)|ensembl:ENSG00000237123(gene)|ensembl:ENSG00000237165(gene)|ensembl:ENST00000259726(transcript)|ensembl:ENST00000418599(transcript)|ensembl:ENST00000445893(transcript)|ensembl:ENST00000457875(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0003336"(corneocyte desquamation)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008544"(epidermis development)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1905716"(negative regulation of cornification)|interpro:IPR026087|mint:Q15517|reactome:R-HSA-6809371|refseq:NP_001255.3 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:brla9icZHYnZBj+2WtExolD2Z489606 rogid:2SaKSq9Py2cPLlytyEiH8znQcd49606 rigid:SBtv0PJkCBV4y4DOwAbMsoBx26A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IE81 uniprotkb:Q13835 intact:EBI-954672|uniprotkb:Q4W5D5|uniprotkb:Q6ZSL7|uniprotkb:Q8NC41|uniprotkb:Q96JL8|uniprotkb:Q96SQ1|uniprotkb:Q9H692|uniprotkb:D3DNY0|uniprotkb:D3DNY1|ensembl:ENSP00000226319|ensembl:ENSP00000425730|ensembl:ENSP00000482212|ensembl:ENSP00000483219 intact:EBI-2513407|ensembl:ENSP00000263946|ensembl:ENSP00000295597|uniprotkb:O00645|uniprotkb:Q14CA0|uniprotkb:Q15152 psi-mi:jade1_human(display_long)|uniprotkb:JADE1(gene name)|psi-mi:JADE1(display_short)|uniprotkb:Jade family PHD finger protein 1(gene name synonym)|uniprotkb:KIAA1807(gene name synonym)|uniprotkb:PHD finger protein 17(gene name synonym)|uniprotkb:PHF17(gene name synonym) psi-mi:pkp1_human(display_long)|uniprotkb:PKP1(gene name)|psi-mi:PKP1(display_short)|uniprotkb:Band 6 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482337|imex:IM-26985-341 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079176.2|refseq:NP_955352.1|refseq:NP_001274372.1|refseq:NP_001274366.1|refseq:NP_001274368.1|refseq:NP_001274369.1|refseq:NP_001274370.1|refseq:NP_001274371.1|ensembl:ENSG00000077684(gene)|ensembl:ENST00000226319(transcript)|ensembl:ENST00000512960(transcript)|ensembl:ENST00000610919(transcript)|ensembl:ENST00000611140(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR039546|mint:Q6IE81|reactome:R-HSA-3214847|refseq:XP_005263289.1 go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0005912"(adherens junction)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0030057"(desmosome)|go:"GO:0030280"(structural constituent of skin epidermis)|go:"GO:0045110"(intermediate filament bundle assembly)|go:"GO:0045296"(cadherin binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1902373"(negative regulation of mRNA catabolic process)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028432|interpro:IPR028435|mint:Q13835|reactome:R-HSA-351906|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371|rcsb pdb:1XM9|ensembl:ENSG00000081277(gene)|ensembl:ENST00000263946(transcript)|ensembl:ENST00000352845(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|refseq:NP_000290.2|refseq:NP_001005337.1 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:brla9icZHYnZBj+2WtExolD2Z489606 rogid:j2bzqEmWBUDLVnjl2JX/i4nI8P49606 rigid:SBtv0PJkCBV4y4DOwAbMsoBx26A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IE81 uniprotkb:P31944 intact:EBI-954672|uniprotkb:Q4W5D5|uniprotkb:Q6ZSL7|uniprotkb:Q8NC41|uniprotkb:Q96JL8|uniprotkb:Q96SQ1|uniprotkb:Q9H692|uniprotkb:D3DNY0|uniprotkb:D3DNY1|ensembl:ENSP00000226319|ensembl:ENSP00000425730|ensembl:ENSP00000482212|ensembl:ENSP00000483219 intact:EBI-2510738|ensembl:ENSP00000393417|uniprotkb:O95823|uniprotkb:Q3SYC9 psi-mi:jade1_human(display_long)|uniprotkb:JADE1(gene name)|psi-mi:JADE1(display_short)|uniprotkb:Jade family PHD finger protein 1(gene name synonym)|uniprotkb:KIAA1807(gene name synonym)|uniprotkb:PHD finger protein 17(gene name synonym)|uniprotkb:PHF17(gene name synonym) psi-mi:caspe_human(display_long)|uniprotkb:CASP14(gene name)|psi-mi:CASP14(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482337|imex:IM-26985-341 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079176.2|refseq:NP_955352.1|refseq:NP_001274372.1|refseq:NP_001274366.1|refseq:NP_001274368.1|refseq:NP_001274369.1|refseq:NP_001274370.1|refseq:NP_001274371.1|ensembl:ENSG00000077684(gene)|ensembl:ENST00000226319(transcript)|ensembl:ENST00000512960(transcript)|ensembl:ENST00000610919(transcript)|ensembl:ENST00000611140(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR039546|mint:Q6IE81|reactome:R-HSA-3214847|refseq:XP_005263289.1 interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR029030|interpro:IPR033139|interpro:IPR033174|mint:P31944|reactome:R-HSA-6809371|ensembl:ENSG00000105141(gene)|ensembl:ENST00000427043(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0031424"(keratinization)|go:"GO:0045095"(keratin filament)|go:"GO:0070268"(cornification)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|refseq:NP_036246.1 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:brla9icZHYnZBj+2WtExolD2Z489606 rogid:e8QPsuebgXeKJEuMm/KU0WAOs3k9606 rigid:SBtv0PJkCBV4y4DOwAbMsoBx26A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IE81 uniprotkb:Q13867 intact:EBI-954672|uniprotkb:Q4W5D5|uniprotkb:Q6ZSL7|uniprotkb:Q8NC41|uniprotkb:Q96JL8|uniprotkb:Q96SQ1|uniprotkb:Q9H692|uniprotkb:D3DNY0|uniprotkb:D3DNY1|ensembl:ENSP00000226319|ensembl:ENSP00000425730|ensembl:ENSP00000482212|ensembl:ENSP00000483219 intact:EBI-718504|uniprotkb:Q53F86|uniprotkb:Q9UER9|uniprotkb:B2R796|ensembl:ENSP00000261714 psi-mi:jade1_human(display_long)|uniprotkb:JADE1(gene name)|psi-mi:JADE1(display_short)|uniprotkb:Jade family PHD finger protein 1(gene name synonym)|uniprotkb:KIAA1807(gene name synonym)|uniprotkb:PHD finger protein 17(gene name synonym)|uniprotkb:PHF17(gene name synonym) psi-mi:blmh_human(display_long)|uniprotkb:BLMH(gene name)|psi-mi:BLMH(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482337|imex:IM-26985-341 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079176.2|refseq:NP_955352.1|refseq:NP_001274372.1|refseq:NP_001274366.1|refseq:NP_001274368.1|refseq:NP_001274369.1|refseq:NP_001274370.1|refseq:NP_001274371.1|ensembl:ENSG00000077684(gene)|ensembl:ENST00000226319(transcript)|ensembl:ENST00000512960(transcript)|ensembl:ENST00000610919(transcript)|ensembl:ENST00000611140(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR039546|mint:Q6IE81|reactome:R-HSA-3214847|refseq:XP_005263289.1 refseq:NP_000377.1|ensembl:ENSG00000108578(gene)|ensembl:ENST00000261714(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043418"(homocysteine catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR004134(Peptidase C1B, bleomycin hydrolase)|interpro:IPR038765|mint:Q13867|rcsb pdb:1CB5|rcsb pdb:2CB5|reactome:R-HSA-983168 - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:brla9icZHYnZBj+2WtExolD2Z489606 rogid:THDv63DC81eQzFvmyWs1rlCBMyk9606 rigid:SBtv0PJkCBV4y4DOwAbMsoBx26A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IE81 uniprotkb:P29508 intact:EBI-954672|uniprotkb:Q4W5D5|uniprotkb:Q6ZSL7|uniprotkb:Q8NC41|uniprotkb:Q96JL8|uniprotkb:Q96SQ1|uniprotkb:Q9H692|uniprotkb:D3DNY0|uniprotkb:D3DNY1|ensembl:ENSP00000226319|ensembl:ENSP00000425730|ensembl:ENSP00000482212|ensembl:ENSP00000483219 intact:EBI-359110|uniprotkb:Q53H28|uniprotkb:Q86VF3|uniprotkb:Q86W04|uniprotkb:Q8IWL4|uniprotkb:Q8IXI3|uniprotkb:Q9BYF8|uniprotkb:Q53YB5|uniprotkb:Q96J21|uniprotkb:B2RBT5|uniprotkb:A6NDM2|uniprotkb:B3W5Y6|ensembl:ENSP00000283752 psi-mi:jade1_human(display_long)|uniprotkb:JADE1(gene name)|psi-mi:JADE1(display_short)|uniprotkb:Jade family PHD finger protein 1(gene name synonym)|uniprotkb:KIAA1807(gene name synonym)|uniprotkb:PHD finger protein 17(gene name synonym)|uniprotkb:PHF17(gene name synonym) psi-mi:spb3_human(display_long)|uniprotkb:SERPINB3(gene name)|psi-mi:SERPINB3(display_short)|uniprotkb:SCCA(gene name synonym)|uniprotkb:SCCA1(gene name synonym)|uniprotkb:Squamous cell carcinoma antigen 1(gene name synonym)|uniprotkb:Protein T4-A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482337|imex:IM-26985-341 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079176.2|refseq:NP_955352.1|refseq:NP_001274372.1|refseq:NP_001274366.1|refseq:NP_001274368.1|refseq:NP_001274369.1|refseq:NP_001274370.1|refseq:NP_001274371.1|ensembl:ENSG00000077684(gene)|ensembl:ENST00000226319(transcript)|ensembl:ENST00000512960(transcript)|ensembl:ENST00000610919(transcript)|ensembl:ENST00000611140(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR039546|mint:Q6IE81|reactome:R-HSA-3214847|refseq:XP_005263289.1 refseq:NP_008850.1|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0035425"(autocrine signaling)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0038001"(paracrine signaling)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P29508|rcsb pdb:2ZV6|rcsb pdb:4ZK0|rcsb pdb:4ZK3|reactome:R-HSA-6798695|ensembl:ENSG00000057149(gene)|ensembl:ENST00000283752(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002020"(protease binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity) - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:brla9icZHYnZBj+2WtExolD2Z489606 rogid:Q6rcSr7BU3XXRUX39SbdLT6Nm5s9606 rigid:SBtv0PJkCBV4y4DOwAbMsoBx26A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IE81 uniprotkb:P47914 intact:EBI-954672|uniprotkb:Q4W5D5|uniprotkb:Q6ZSL7|uniprotkb:Q8NC41|uniprotkb:Q96JL8|uniprotkb:Q96SQ1|uniprotkb:Q9H692|uniprotkb:D3DNY0|uniprotkb:D3DNY1|ensembl:ENSP00000226319|ensembl:ENSP00000425730|ensembl:ENSP00000482212|ensembl:ENSP00000483219 intact:EBI-714039|uniprotkb:Q6IPY3|ensembl:ENSP00000418346|ensembl:ENSP00000418868|ensembl:ENSP00000420673|ensembl:ENSP00000294189|ensembl:ENSP00000417048|ensembl:ENSP00000418153|uniprotkb:B2R4M8|uniprotkb:A8K0H3 psi-mi:jade1_human(display_long)|uniprotkb:JADE1(gene name)|psi-mi:JADE1(display_short)|uniprotkb:Jade family PHD finger protein 1(gene name synonym)|uniprotkb:KIAA1807(gene name synonym)|uniprotkb:PHD finger protein 17(gene name synonym)|uniprotkb:PHF17(gene name synonym) psi-mi:rl29_human(display_long)|uniprotkb:Cell surface heparin-binding protein HIP(gene name synonym)|uniprotkb:RPL29(gene name)|psi-mi:RPL29(display_short)|uniprotkb:Large ribosomal subunit protein eL29(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482337|imex:IM-26985-341 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079176.2|refseq:NP_955352.1|refseq:NP_001274372.1|refseq:NP_001274366.1|refseq:NP_001274368.1|refseq:NP_001274369.1|refseq:NP_001274370.1|refseq:NP_001274371.1|ensembl:ENSG00000077684(gene)|ensembl:ENST00000226319(transcript)|ensembl:ENST00000512960(transcript)|ensembl:ENST00000610919(transcript)|ensembl:ENST00000611140(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR039546|mint:Q6IE81|reactome:R-HSA-3214847|refseq:XP_005263289.1 ensembl:ENST00000294189(transcript)|ensembl:ENST00000466397(transcript)|ensembl:ENST00000475248(transcript)|ensembl:ENST00000479017(transcript)|ensembl:ENST00000492277(transcript)|ensembl:ENST00000495383(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0007566"(embryo implantation)|go:"GO:0008201"(heparin binding)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR002673(Ribosomal protein L29e)|mint:P47914|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|ensembl:ENSG00000162244(gene)|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_000983.1|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339 - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:brla9icZHYnZBj+2WtExolD2Z489606 rogid:XZUSMDDzycAi6QEXYbljXaeVg0U9606 rigid:SBtv0PJkCBV4y4DOwAbMsoBx26A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IE81 uniprotkb:P62736 intact:EBI-954672|uniprotkb:Q4W5D5|uniprotkb:Q6ZSL7|uniprotkb:Q8NC41|uniprotkb:Q96JL8|uniprotkb:Q96SQ1|uniprotkb:Q9H692|uniprotkb:D3DNY0|uniprotkb:D3DNY1|ensembl:ENSP00000226319|ensembl:ENSP00000425730|ensembl:ENSP00000482212|ensembl:ENSP00000483219 intact:EBI-698810|uniprotkb:P03996|uniprotkb:P04108|uniprotkb:Q6FI19|uniprotkb:B2R8A4|ensembl:ENSP00000224784 psi-mi:jade1_human(display_long)|uniprotkb:JADE1(gene name)|psi-mi:JADE1(display_short)|uniprotkb:Jade family PHD finger protein 1(gene name synonym)|uniprotkb:KIAA1807(gene name synonym)|uniprotkb:PHD finger protein 17(gene name synonym)|uniprotkb:PHF17(gene name synonym) psi-mi:acta_human(display_long)|uniprotkb:Alpha-actin-2(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 46 protein(gene name synonym)|uniprotkb:ACTA2(gene name)|psi-mi:ACTA2(display_short)|uniprotkb:ACTSA(gene name synonym)|uniprotkb:ACTVS(gene name synonym)|uniprotkb:GIG46(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482337|imex:IM-26985-341 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079176.2|refseq:NP_955352.1|refseq:NP_001274372.1|refseq:NP_001274366.1|refseq:NP_001274368.1|refseq:NP_001274369.1|refseq:NP_001274370.1|refseq:NP_001274371.1|ensembl:ENSG00000077684(gene)|ensembl:ENST00000226319(transcript)|ensembl:ENST00000512960(transcript)|ensembl:ENST00000610919(transcript)|ensembl:ENST00000611140(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR039546|mint:Q6IE81|reactome:R-HSA-3214847|refseq:XP_005263289.1 refseq:NP_001135417.1|refseq:NP_001604.1|refseq:NP_001307784.1|ensembl:ENSG00000107796(gene)|ensembl:ENST00000224784(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0009615"(response to virus)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014829"(vascular associated smooth muscle contraction)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030485"(smooth muscle contractile fiber)|go:"GO:0032991"(protein-containing complex)|go:"GO:0044297"(cell body)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072144"(glomerular mesangial cell development)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P62736|reactome:R-HSA-445355|reactome:R-HSA-9013695 - - comment:"author score: 32" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:brla9icZHYnZBj+2WtExolD2Z489606 rogid:mRZGUdL/jBuj6nVHtxoasZuA7yA9606 rigid:SBtv0PJkCBV4y4DOwAbMsoBx26A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IE81 uniprotkb:P07339 intact:EBI-954672|uniprotkb:Q4W5D5|uniprotkb:Q6ZSL7|uniprotkb:Q8NC41|uniprotkb:Q96JL8|uniprotkb:Q96SQ1|uniprotkb:Q9H692|uniprotkb:D3DNY0|uniprotkb:D3DNY1|ensembl:ENSP00000226319|ensembl:ENSP00000425730|ensembl:ENSP00000482212|ensembl:ENSP00000483219 intact:EBI-2115097|uniprotkb:Q6IB57|ensembl:ENSP00000236671 psi-mi:jade1_human(display_long)|uniprotkb:JADE1(gene name)|psi-mi:JADE1(display_short)|uniprotkb:Jade family PHD finger protein 1(gene name synonym)|uniprotkb:KIAA1807(gene name synonym)|uniprotkb:PHD finger protein 17(gene name synonym)|uniprotkb:PHF17(gene name synonym) psi-mi:catd_human(display_long)|uniprotkb:CTSD(gene name)|psi-mi:CTSD(display_short)|uniprotkb:CPSD(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482337|imex:IM-26985-341 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079176.2|refseq:NP_955352.1|refseq:NP_001274372.1|refseq:NP_001274366.1|refseq:NP_001274368.1|refseq:NP_001274369.1|refseq:NP_001274370.1|refseq:NP_001274371.1|ensembl:ENSG00000077684(gene)|ensembl:ENST00000226319(transcript)|ensembl:ENST00000512960(transcript)|ensembl:ENST00000610919(transcript)|ensembl:ENST00000611140(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR039546|mint:Q6IE81|reactome:R-HSA-3214847|refseq:XP_005263289.1 refseq:NP_001900.1|dip:DIP-43906N|ensembl:ENSG00000117984(gene)|ensembl:ENST00000236671(transcript)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0008233"(peptidase activity)|go:"GO:0010008"(endosome membrane)|go:"GO:0019886"(antigen processing and presentation of exogenous peptide antigen via MHC class II)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042159"(lipoprotein catabolic process)|go:"GO:0042470"(melanosome)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070001"(aspartic-type peptidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001461(Peptidase A1)|interpro:IPR001969(Peptidase aspartic, active site)|interpro:IPR012848(Propeptide, peptidase A1)|interpro:IPR021109|interpro:IPR033121|interpro:IPR033144|mint:P07339|rcsb pdb:1LYA|rcsb pdb:1LYB|rcsb pdb:1LYW|rcsb pdb:4OBZ|rcsb pdb:4OC6|rcsb pdb:4OD9|reactome:R-HSA-1442490|reactome:R-HSA-2022377|reactome:R-HSA-2132295|reactome:R-HSA-6798695|reactome:R-HSA-9018519 - - comment:"author score: 33" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:brla9icZHYnZBj+2WtExolD2Z489606 rogid:M1qLQBlL2DSCZiAwIPee9Vza3dU9606 rigid:SBtv0PJkCBV4y4DOwAbMsoBx26A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IE81 uniprotkb:P36952 intact:EBI-954672|uniprotkb:Q4W5D5|uniprotkb:Q6ZSL7|uniprotkb:Q8NC41|uniprotkb:Q96JL8|uniprotkb:Q96SQ1|uniprotkb:Q9H692|uniprotkb:D3DNY0|uniprotkb:D3DNY1|ensembl:ENSP00000226319|ensembl:ENSP00000425730|ensembl:ENSP00000482212|ensembl:ENSP00000483219 intact:EBI-2371394|uniprotkb:B2R6Y4|uniprotkb:Q6N0B4|uniprotkb:Q8WW89|ensembl:ENSP00000372221 psi-mi:jade1_human(display_long)|uniprotkb:JADE1(gene name)|psi-mi:JADE1(display_short)|uniprotkb:Jade family PHD finger protein 1(gene name synonym)|uniprotkb:KIAA1807(gene name synonym)|uniprotkb:PHD finger protein 17(gene name synonym)|uniprotkb:PHF17(gene name synonym) psi-mi:spb5_human(display_long)|uniprotkb:SERPINB5(gene name)|psi-mi:SERPINB5(display_short)|uniprotkb:PI5(gene name synonym)|uniprotkb:Peptidase inhibitor 5(gene name synonym)|uniprotkb:Maspin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482337|imex:IM-26985-341 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079176.2|refseq:NP_955352.1|refseq:NP_001274372.1|refseq:NP_001274366.1|refseq:NP_001274368.1|refseq:NP_001274369.1|refseq:NP_001274370.1|refseq:NP_001274371.1|ensembl:ENSG00000077684(gene)|ensembl:ENST00000226319(transcript)|ensembl:ENST00000512960(transcript)|ensembl:ENST00000610919(transcript)|ensembl:ENST00000611140(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR039546|mint:Q6IE81|reactome:R-HSA-3214847|refseq:XP_005263289.1 refseq:NP_002630.2|ensembl:ENSG00000206075(gene)|ensembl:ENST00000382771(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0060512"(prostate gland morphogenesis)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR000240(Serpin B9 and maspin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR033836|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P36952|rcsb pdb:1WZ9|rcsb pdb:1XQG|rcsb pdb:1XQJ|rcsb pdb:1XU8 - - comment:"author score: 39" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:brla9icZHYnZBj+2WtExolD2Z489606 rogid:p2g5mTsqtSjgS73Zvoy64BV5Zes9606 rigid:SBtv0PJkCBV4y4DOwAbMsoBx26A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IE81 uniprotkb:P07476 intact:EBI-954672|uniprotkb:Q4W5D5|uniprotkb:Q6ZSL7|uniprotkb:Q8NC41|uniprotkb:Q96JL8|uniprotkb:Q96SQ1|uniprotkb:Q9H692|uniprotkb:D3DNY0|uniprotkb:D3DNY1|ensembl:ENSP00000226319|ensembl:ENSP00000425730|ensembl:ENSP00000482212|ensembl:ENSP00000483219 intact:EBI-11307220|uniprotkb:Q5T7P4|intact:EBI-28974501|ensembl:ENSP00000357753 psi-mi:jade1_human(display_long)|uniprotkb:JADE1(gene name)|psi-mi:JADE1(display_short)|uniprotkb:Jade family PHD finger protein 1(gene name synonym)|uniprotkb:KIAA1807(gene name synonym)|uniprotkb:PHD finger protein 17(gene name synonym)|uniprotkb:PHF17(gene name synonym) psi-mi:invo_human(display_long)|uniprotkb:IVL(gene name)|psi-mi:IVL(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482337|imex:IM-26985-341 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079176.2|refseq:NP_955352.1|refseq:NP_001274372.1|refseq:NP_001274366.1|refseq:NP_001274368.1|refseq:NP_001274369.1|refseq:NP_001274370.1|refseq:NP_001274371.1|ensembl:ENSG00000077684(gene)|ensembl:ENST00000226319(transcript)|ensembl:ENST00000512960(transcript)|ensembl:ENST00000610919(transcript)|ensembl:ENST00000611140(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR039546|mint:Q6IE81|reactome:R-HSA-3214847|refseq:XP_005263289.1 ensembl:ENSP00000357753|refseq:NP_005538.2|ensembl:ENSG00000163207(gene)|ensembl:ENST00000368764(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0010224"(response to UV-B)|go:"GO:0016604"(nuclear body)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0018153"("isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine")|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0031424"(keratinization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000354(Involucrin repeat)|interpro:IPR002360(Involucrin)|interpro:IPR019571|interpro:IPR019743|mint:P07476|rcsb pdb:1EU0|reactome:R-HSA-6809371 - - comment:"author score: 39" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:brla9icZHYnZBj+2WtExolD2Z489606 rogid:1ZHgB7J+AXcC45RMlCMkoEwUta49606 rigid:SBtv0PJkCBV4y4DOwAbMsoBx26A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IE81 uniprotkb:P31947 intact:EBI-954672|uniprotkb:Q4W5D5|uniprotkb:Q6ZSL7|uniprotkb:Q8NC41|uniprotkb:Q96JL8|uniprotkb:Q96SQ1|uniprotkb:Q9H692|uniprotkb:D3DNY0|uniprotkb:D3DNY1|ensembl:ENSP00000226319|ensembl:ENSP00000425730|ensembl:ENSP00000482212|ensembl:ENSP00000483219 intact:EBI-476295|uniprotkb:Q6FH30|uniprotkb:Q6FH51|uniprotkb:Q96DH0|ensembl:ENSP00000340989|intact:EBI-28970316 psi-mi:jade1_human(display_long)|uniprotkb:JADE1(gene name)|psi-mi:JADE1(display_short)|uniprotkb:Jade family PHD finger protein 1(gene name synonym)|uniprotkb:KIAA1807(gene name synonym)|uniprotkb:PHD finger protein 17(gene name synonym)|uniprotkb:PHF17(gene name synonym) psi-mi:1433s_human(display_long)|uniprotkb:Stratifin(gene name synonym)|uniprotkb:Epithelial cell marker protein 1(gene name synonym)|uniprotkb:HME1(gene name synonym)|uniprotkb:SFN(gene name)|psi-mi:SFN(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482337|imex:IM-26985-341 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079176.2|refseq:NP_955352.1|refseq:NP_001274372.1|refseq:NP_001274366.1|refseq:NP_001274368.1|refseq:NP_001274369.1|refseq:NP_001274370.1|refseq:NP_001274371.1|ensembl:ENSG00000077684(gene)|ensembl:ENST00000226319(transcript)|ensembl:ENST00000512960(transcript)|ensembl:ENST00000610919(transcript)|ensembl:ENST00000611140(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR039546|mint:Q6IE81|reactome:R-HSA-3214847|refseq:XP_005263289.1 ensembl:ENSP00000340989|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031424"(keratinization)|ensembl:ENSG00000175793(gene)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|ensembl:ENST00000339276(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0045606"(positive regulation of epidermal cell differentiation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|go:"GO:0003334"(keratinocyte development)|interpro:IPR023409|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007165"(signal transduction)|go:"GO:0008426"(protein kinase C inhibitor activity)|interpro:IPR023410|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010482"(regulation of epidermal cell division)|interpro:IPR036815|interpro:IPR037435|mint:P31947|rcsb pdb:1YWT|rcsb pdb:3IQJ|rcsb pdb:3IQU|rcsb pdb:3IQV|rcsb pdb:3LW1|rcsb pdb:3MHR|rcsb pdb:3O8I|rcsb pdb:3P1N|rcsb pdb:3P1O|rcsb pdb:3P1P|rcsb pdb:3P1Q|rcsb pdb:3P1R|rcsb pdb:3P1S|rcsb pdb:3SMK|rcsb pdb:3SML|rcsb pdb:3SMM|rcsb pdb:3SMN|rcsb pdb:3SMO|rcsb pdb:3SP5|rcsb pdb:3SPR|rcsb pdb:3T0L|rcsb pdb:3T0M|rcsb pdb:3U9X|rcsb pdb:3UX0|rcsb pdb:4DAT|rcsb pdb:4DAU|rcsb pdb:4DHM|rcsb pdb:4DHN|rcsb pdb:4DHO|rcsb pdb:4DHP|rcsb pdb:4DHQ|rcsb pdb:4DHR|rcsb pdb:4DHS|rcsb pdb:4DHT|rcsb pdb:4DHU|rcsb pdb:4FL5|rcsb pdb:4FR3|rcsb pdb:4IEA|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4QLI|rcsb pdb:4Y32|rcsb pdb:4Y3B|rcsb pdb:4Y5I|rcsb pdb:5BTV|rcsb pdb:5HF3|rcsb pdb:1YZ5|rcsb pdb:5LTW|rcsb pdb:5LU1|rcsb pdb:5LU2|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5MXO|rcsb pdb:7O34|rcsb pdb:7O3A|rcsb pdb:7O3F|rcsb pdb:7O3P|rcsb pdb:7O3Q|rcsb pdb:7NZV|rcsb pdb:7O3R|rcsb pdb:7O3S|rcsb pdb:7O57|rcsb pdb:7O59|rcsb pdb:7O5A|rcsb pdb:7O5C|rcsb pdb:7O5D|rcsb pdb:7O5F|rcsb pdb:7O5G|rcsb pdb:7O5O|rcsb pdb:7O5P|rcsb pdb:7O5S|rcsb pdb:7O5U|rcsb pdb:7O5X|rcsb pdb:7O6F|rcsb pdb:7O6G|rcsb pdb:7O6I|rcsb pdb:7O6J|rcsb pdb:7O6K|rcsb pdb:7O6M|rcsb pdb:7O6O|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|rcsb pdb:6GHP|rcsb pdb:6HHP|rcsb pdb:6HKB|rcsb pdb:6HKF|rcsb pdb:6HMT|rcsb pdb:6G8Q|rcsb pdb:6HMU|rcsb pdb:6HN2|rcsb pdb:6NV2|rcsb pdb:6QDR|rcsb pdb:6QDS|rcsb pdb:6QDT|rcsb pdb:6QDU|rcsb pdb:6QHL|rcsb pdb:6QHM|rcsb pdb:6QIU|rcsb pdb:6QZR|rcsb pdb:6QZS|rcsb pdb:6R5L|rcsb pdb:6RHC|rcsb pdb:6RJL|rcsb pdb:6RJQ|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RP6|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:5MYC|rcsb pdb:5N5R|rcsb pdb:5N5T|rcsb pdb:5N5W|rcsb pdb:5N75|rcsb pdb:5OEG|rcsb pdb:5OEH|rcsb pdb:5OK9|rcsb pdb:5OKF|rcsb pdb:5OM0|rcsb pdb:5OMA|rcsb pdb:6FAU|rcsb pdb:6FAV|rcsb pdb:6FAW|rcsb pdb:6FBB|rcsb pdb:6FBW|rcsb pdb:6FBY|rcsb pdb:6FCP|rcsb pdb:6FI4|rcsb pdb:6FI5|rcsb pdb:6G6X|rcsb pdb:6G8I|rcsb pdb:5MY9|rcsb pdb:6G8J|rcsb pdb:6G8K|rcsb pdb:6G8L|rcsb pdb:6G8P|rcsb pdb:6RWS|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6RWU|rcsb pdb:6TLF|rcsb pdb:6TLG|rcsb pdb:6TM7|rcsb pdb:6TWZ|rcsb pdb:6W0L|rcsb pdb:6XWD|rcsb pdb:6XXC|rcsb pdb:6XY5|rcsb pdb:6Y18|rcsb pdb:6Y1D|rcsb pdb:6Y1J|rcsb pdb:6RX2|rcsb pdb:6S39|rcsb pdb:6S3C|rcsb pdb:6S40|rcsb pdb:6Y3M|rcsb pdb:6Y3O|rcsb pdb:6Y3R|rcsb pdb:6Y3S|rcsb pdb:6Y3V|rcsb pdb:6Y3W|rcsb pdb:6Y40|rcsb pdb:6S9Q|rcsb pdb:6Y44|rcsb pdb:6SIN|rcsb pdb:6Y58|rcsb pdb:6SIO|rcsb pdb:6Y7T|rcsb pdb:6SIP|rcsb pdb:6Y8A|rcsb pdb:6Y8B|rcsb pdb:6Y8D|rcsb pdb:6SIQ|rcsb pdb:6Y8E|rcsb pdb:6YE9|rcsb pdb:6YIA|rcsb pdb:6SLV|rcsb pdb:6YIB|rcsb pdb:6YIC|rcsb pdb:6YLU|rcsb pdb:6YOW|rcsb pdb:6YOX|rcsb pdb:6YOY|rcsb pdb:6YP2|rcsb pdb:6YP3|rcsb pdb:6YP8|rcsb pdb:6SLW|rcsb pdb:6SLX|rcsb pdb:6T5F|rcsb pdb:6T5H|rcsb pdb:6T80|rcsb pdb:6TCH|rcsb pdb:6YPL|rcsb pdb:6YPY|rcsb pdb:6YQ2|rcsb pdb:6ZCJ|rcsb pdb:7AEW|rcsb pdb:7AOG|rcsb pdb:7AXN|rcsb pdb:7AYF|rcsb pdb:7AZ1|rcsb pdb:7AZ2|rcsb pdb:7BDP|rcsb pdb:7BDT|rcsb pdb:7BDY|rcsb pdb:7BFW|rcsb pdb:7BG3|rcsb pdb:7BGQ|rcsb pdb:7BGR|rcsb pdb:7BGV|rcsb pdb:7BGW|rcsb pdb:7BI3|rcsb pdb:7BIQ|rcsb pdb:7BIY|rcsb pdb:7BJF|rcsb pdb:7BJL|rcsb pdb:7BJW|rcsb pdb:7BKH|rcsb pdb:7NFW|rcsb pdb:7NIF|rcsb pdb:7NIG|rcsb pdb:7NIX|rcsb pdb:7NJ6|rcsb pdb:7NJ8|rcsb pdb:7NJ9|rcsb pdb:7NJA|rcsb pdb:7NJB|rcsb pdb:7NK3|rcsb pdb:7NK5|rcsb pdb:7NLA|rcsb pdb:7NLE|rcsb pdb:7NM1|rcsb pdb:7NM3|rcsb pdb:7NM9|rcsb pdb:7NQP|rcsb pdb:7NR7|rcsb pdb:7NRK|rcsb pdb:7NRL|rcsb pdb:7NSV|rcsb pdb:7NV4|rcsb pdb:7NVI|rcsb pdb:7NWS|rcsb pdb:7NXS|rcsb pdb:7NXT|rcsb pdb:7NXW|rcsb pdb:7NXY|rcsb pdb:7NY4|rcsb pdb:7NYE|rcsb pdb:7NYF|rcsb pdb:7NYG|rcsb pdb:7NZ6|rcsb pdb:7NZG|rcsb pdb:7NZK|reactome:R-HSA-6804114|reactome:R-HSA-75035|reactome:R-HSA-9614399|refseq:NP_006133.1|dip:DIP-29861N - - comment:"author score: 41" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:brla9icZHYnZBj+2WtExolD2Z489606 rogid:HI+I1sXZRxVaRy9nzl3O0HmaSSE9606 rigid:SBtv0PJkCBV4y4DOwAbMsoBx26A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IE81 uniprotkb:Q13283 intact:EBI-954672|uniprotkb:Q4W5D5|uniprotkb:Q6ZSL7|uniprotkb:Q8NC41|uniprotkb:Q96JL8|uniprotkb:Q96SQ1|uniprotkb:Q9H692|uniprotkb:D3DNY0|uniprotkb:D3DNY1|ensembl:ENSP00000226319|ensembl:ENSP00000425730|ensembl:ENSP00000482212|ensembl:ENSP00000483219 intact:EBI-1047359|intact:EBI-1384154|ensembl:ENSP00000348578|ensembl:ENSP00000377681|ensembl:ENSP00000430480|ensembl:ENSP00000502880|ensembl:ENSP00000503039|ensembl:ENSP00000503699|ensembl:ENSP00000503939|ensembl:ENSP00000504140|ensembl:ENSP00000504627|uniprotkb:Q5HYE9 psi-mi:jade1_human(display_long)|uniprotkb:JADE1(gene name)|psi-mi:JADE1(display_short)|uniprotkb:Jade family PHD finger protein 1(gene name synonym)|uniprotkb:KIAA1807(gene name synonym)|uniprotkb:PHD finger protein 17(gene name synonym)|uniprotkb:PHF17(gene name synonym) psi-mi:g3bp1_human(display_long)|uniprotkb:G3BP1(gene name)|psi-mi:G3BP1(display_short)|uniprotkb:G3BP(gene name synonym)|uniprotkb:ATP-dependent DNA helicase VIII(gene name synonym)|uniprotkb:GAP SH3 domain-binding protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482337|imex:IM-26985-341 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079176.2|refseq:NP_955352.1|refseq:NP_001274372.1|refseq:NP_001274366.1|refseq:NP_001274368.1|refseq:NP_001274369.1|refseq:NP_001274370.1|refseq:NP_001274371.1|ensembl:ENSG00000077684(gene)|ensembl:ENST00000226319(transcript)|ensembl:ENST00000512960(transcript)|ensembl:ENST00000610919(transcript)|ensembl:ENST00000611140(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR039546|mint:Q6IE81|reactome:R-HSA-3214847|refseq:XP_005263289.1 refseq:NP_005745.1|refseq:NP_938405.1|ensembl:ENSG00000145907(gene)|go:"GO:0003729"(mRNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0033677"(DNA/RNA helicase activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043204"(perikaryon)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0062029"(positive regulation of stress granule assembly)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018222|interpro:IPR032710|interpro:IPR034374|interpro:IPR034375|interpro:IPR035979|interpro:IPR039539|mint:Q13283|ensembl:ENST00000356245(transcript)|rcsb pdb:3Q90|rcsb pdb:4FCJ|rcsb pdb:4FCM|rcsb pdb:4IIA|rcsb pdb:5FW5|rcsb pdb:6TA7|ensembl:ENST00000394123(transcript)|ensembl:ENST00000522761(transcript)|ensembl:ENST00000676827(transcript)|ensembl:ENST00000676978(transcript)|ensembl:ENST00000677323(transcript)|ensembl:ENST00000678070(transcript)|ensembl:ENST00000678101(transcript)|ensembl:ENST00000678925(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|refseq:XP_006714812.1|refseq:XP_006714813.1|refseq:XP_016864411.1|refseq:XP_016864412.1 - - comment:"author score: 42" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:brla9icZHYnZBj+2WtExolD2Z489606 rogid:0ZRCHNVEmmtGEOASNwg3kIm2uys9606 rigid:SBtv0PJkCBV4y4DOwAbMsoBx26A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IE81 uniprotkb:Q8WVV4 intact:EBI-954672|uniprotkb:Q4W5D5|uniprotkb:Q6ZSL7|uniprotkb:Q8NC41|uniprotkb:Q96JL8|uniprotkb:Q96SQ1|uniprotkb:Q9H692|uniprotkb:D3DNY0|uniprotkb:D3DNY1|ensembl:ENSP00000226319|ensembl:ENSP00000425730|ensembl:ENSP00000482212|ensembl:ENSP00000483219 intact:EBI-2877727|ensembl:ENSP00000262753|uniprotkb:Q9H738|uniprotkb:Q9H744|uniprotkb:Q5H9F0|uniprotkb:Q8NG12|uniprotkb:Q5H9E9|uniprotkb:Q9H5Y2|uniprotkb:A8K2U5 psi-mi:jade1_human(display_long)|uniprotkb:JADE1(gene name)|psi-mi:JADE1(display_short)|uniprotkb:Jade family PHD finger protein 1(gene name synonym)|uniprotkb:KIAA1807(gene name synonym)|uniprotkb:PHD finger protein 17(gene name synonym)|uniprotkb:PHF17(gene name synonym) psi-mi:pof1b_human(display_long)|uniprotkb:POF1B(gene name)|psi-mi:POF1B(display_short)|uniprotkb:Premature ovarian failure protein 1B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482337|imex:IM-26985-341 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079176.2|refseq:NP_955352.1|refseq:NP_001274372.1|refseq:NP_001274366.1|refseq:NP_001274368.1|refseq:NP_001274369.1|refseq:NP_001274370.1|refseq:NP_001274371.1|ensembl:ENSG00000077684(gene)|ensembl:ENST00000226319(transcript)|ensembl:ENST00000512960(transcript)|ensembl:ENST00000610919(transcript)|ensembl:ENST00000611140(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR039546|mint:Q6IE81|reactome:R-HSA-3214847|refseq:XP_005263289.1 ensembl:ENST00000262753(transcript)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005884"(actin filament)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030057"(desmosome)|go:"GO:0051015"(actin filament binding)|go:"GO:0070830"(bicellular tight junction assembly)|interpro:IPR026186|mint:Q8WVV4|rcsb pdb:3BH9|ensembl:ENSG00000124429(gene)|refseq:NP_001294869.1|refseq:NP_079197.3|ensembl:ENSP00000262753|ensembl:ENST00000373145|ensembl:ENSP00000362238 - - comment:"author score: 53" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:brla9icZHYnZBj+2WtExolD2Z489606 rogid:rigOH+ulgEPejDWfjfmcn2M2B2M9606 rigid:SBtv0PJkCBV4y4DOwAbMsoBx26A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IE81 uniprotkb:Q9NZT1 intact:EBI-954672|uniprotkb:Q4W5D5|uniprotkb:Q6ZSL7|uniprotkb:Q8NC41|uniprotkb:Q96JL8|uniprotkb:Q96SQ1|uniprotkb:Q9H692|uniprotkb:D3DNY0|uniprotkb:D3DNY1|ensembl:ENSP00000226319|ensembl:ENSP00000425730|ensembl:ENSP00000482212|ensembl:ENSP00000483219 intact:EBI-1051681|uniprotkb:Q8IXU8|uniprotkb:Q5SQI3|ensembl:ENSP00000369689 psi-mi:jade1_human(display_long)|uniprotkb:JADE1(gene name)|psi-mi:JADE1(display_short)|uniprotkb:Jade family PHD finger protein 1(gene name synonym)|uniprotkb:KIAA1807(gene name synonym)|uniprotkb:PHD finger protein 17(gene name synonym)|uniprotkb:PHF17(gene name synonym) psi-mi:call5_human(display_long)|uniprotkb:Calmodulin-like skin protein(gene name synonym)|uniprotkb:CALML5(gene name)|psi-mi:CALML5(display_short)|uniprotkb:CLSP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482337|imex:IM-26985-341 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079176.2|refseq:NP_955352.1|refseq:NP_001274372.1|refseq:NP_001274366.1|refseq:NP_001274368.1|refseq:NP_001274369.1|refseq:NP_001274370.1|refseq:NP_001274371.1|ensembl:ENSG00000077684(gene)|ensembl:ENST00000226319(transcript)|ensembl:ENST00000512960(transcript)|ensembl:ENST00000610919(transcript)|ensembl:ENST00000611140(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR039546|mint:Q6IE81|reactome:R-HSA-3214847|refseq:XP_005263289.1 refseq:NP_059118.2|ensembl:ENST00000380332(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007165"(signal transduction)|go:"GO:0008544"(epidermis development)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q9NZT1|rcsb pdb:2B1U|reactome:R-HSA-6798695|ensembl:ENSG00000178372(gene) - - comment:"author score: 54" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:brla9icZHYnZBj+2WtExolD2Z489606 rogid:uPD/avsoqpiogqHCK5TGJQwvCX89606 rigid:SBtv0PJkCBV4y4DOwAbMsoBx26A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IE81 uniprotkb:P47929 intact:EBI-954672|uniprotkb:Q4W5D5|uniprotkb:Q6ZSL7|uniprotkb:Q8NC41|uniprotkb:Q96JL8|uniprotkb:Q96SQ1|uniprotkb:Q9H692|uniprotkb:D3DNY0|uniprotkb:D3DNY1|ensembl:ENSP00000226319|ensembl:ENSP00000425730|ensembl:ENSP00000482212|ensembl:ENSP00000483219 intact:EBI-357504|ensembl:ENSP00000313571|ensembl:ENSP00000367891|ensembl:ENSP00000489395|ensembl:ENSP00000489582|uniprotkb:Q6IB87 psi-mi:jade1_human(display_long)|uniprotkb:JADE1(gene name)|psi-mi:JADE1(display_short)|uniprotkb:Jade family PHD finger protein 1(gene name synonym)|uniprotkb:KIAA1807(gene name synonym)|uniprotkb:PHD finger protein 17(gene name synonym)|uniprotkb:PHF17(gene name synonym) psi-mi:leg7_human(display_long)|uniprotkb:LGALS7(gene name)|psi-mi:LGALS7(display_short)|uniprotkb:PIG1(gene name synonym)|uniprotkb:HKL-14(gene name synonym)|uniprotkb:PI7(gene name synonym)|uniprotkb:p53-induced gene 1 protein(gene name synonym)|uniprotkb:LGALS7B(gene name)|psi-mi:LGALS7B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482337|imex:IM-26985-341 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079176.2|refseq:NP_955352.1|refseq:NP_001274372.1|refseq:NP_001274366.1|refseq:NP_001274368.1|refseq:NP_001274369.1|refseq:NP_001274370.1|refseq:NP_001274371.1|ensembl:ENSG00000077684(gene)|ensembl:ENST00000226319(transcript)|ensembl:ENST00000512960(transcript)|ensembl:ENST00000610919(transcript)|ensembl:ENST00000611140(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR039546|mint:Q6IE81|reactome:R-HSA-3214847|refseq:XP_005263289.1 ensembl:ENSG00000178934(gene)|ensembl:ENSG00000205076(gene)|ensembl:ENSG00000282902(gene)|ensembl:ENSG00000283082(gene)|ensembl:ENST00000314980(transcript)|ensembl:ENST00000378626(transcript)|ensembl:ENST00000634448(transcript)|ensembl:ENST00000634800(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016936"(galactoside binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000562"(negative regulation of CD4-positive, alpha-beta T cell proliferation)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR030640|interpro:IPR044156|mint:P47929|rcsb pdb:1BKZ|rcsb pdb:2GAL|rcsb pdb:3GAL|rcsb pdb:3ZXE|rcsb pdb:3ZXF|rcsb pdb:4GAL|rcsb pdb:4UW3|rcsb pdb:4UW4|rcsb pdb:4UW5|rcsb pdb:4UW6|rcsb pdb:4XBQ|rcsb pdb:4Y26|rcsb pdb:5GAL|rcsb pdb:5H9Q|rcsb pdb:5H9S|refseq:NP_001035972.1|refseq:NP_002298.1 - - comment:"author score: 110" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:brla9icZHYnZBj+2WtExolD2Z489606 rogid:TIAlvVZ7rOYqTAGrYAFbJY231gc9606 rigid:SBtv0PJkCBV4y4DOwAbMsoBx26A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IE81 uniprotkb:O95251 intact:EBI-954672|uniprotkb:Q4W5D5|uniprotkb:Q6ZSL7|uniprotkb:Q8NC41|uniprotkb:Q96JL8|uniprotkb:Q96SQ1|uniprotkb:Q9H692|uniprotkb:D3DNY0|uniprotkb:D3DNY1|ensembl:ENSP00000226319|ensembl:ENSP00000425730|ensembl:ENSP00000482212|ensembl:ENSP00000483219 intact:EBI-473199|uniprotkb:B3KN74|uniprotkb:B4DFB4|uniprotkb:B4DFE0|uniprotkb:B4DF85|uniprotkb:B4DGY4|uniprotkb:E7ER15|uniprotkb:G5E9K7|intact:EBI-10986821|ensembl:ENSP00000259021 psi-mi:jade1_human(display_long)|uniprotkb:JADE1(gene name)|psi-mi:JADE1(display_short)|uniprotkb:Jade family PHD finger protein 1(gene name synonym)|uniprotkb:KIAA1807(gene name synonym)|uniprotkb:PHD finger protein 17(gene name synonym)|uniprotkb:PHF17(gene name synonym) psi-mi:kat7_human(display_long)|uniprotkb:KAT7(gene name)|psi-mi:KAT7(display_short)|uniprotkb:HBO1(gene name synonym)|uniprotkb:HBOa(gene name synonym)|uniprotkb:MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2(gene name synonym)|uniprotkb:Histone acetyltransferase binding to ORC1(gene name synonym)|uniprotkb:MYST2(gene name synonym)|uniprotkb:Lysine acetyltransferase 7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482337|imex:IM-26985-341 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079176.2|refseq:NP_955352.1|refseq:NP_001274372.1|refseq:NP_001274366.1|refseq:NP_001274368.1|refseq:NP_001274369.1|refseq:NP_001274370.1|refseq:NP_001274371.1|ensembl:ENSG00000077684(gene)|ensembl:ENST00000226319(transcript)|ensembl:ENST00000512960(transcript)|ensembl:ENST00000610919(transcript)|ensembl:ENST00000611140(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016607"(nuclear speck)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019542|interpro:IPR019786|interpro:IPR019787|interpro:IPR034732|interpro:IPR039546|mint:Q6IE81|reactome:R-HSA-3214847|refseq:XP_005263289.1 refseq:NP_001186084.1|refseq:NP_001186085.1|refseq:NP_001186086.1|refseq:NP_001186087.1|refseq:NP_008998.1|dip:DIP-29697N|ensembl:ENSG00000136504(gene)|ensembl:ENST00000259021(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001779"(natural killer cell differentiation)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0018393"(internal peptidyl-lysine acetylation)|go:"GO:0030174"(regulation of DNA-dependent DNA replication initiation)|go:"GO:0031098"(stress-activated protein kinase signaling cascade)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0036409"(histone H3-K14 acetyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043983"(histone H4-K12 acetylation)|go:"GO:0044154"(histone H3-K14 acetylation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0072708"(response to sorbitol)|go:"GO:0072710"(response to hydroxyurea)|go:"GO:0072716"(response to actinomycin D)|go:"GO:0072720"(response to dithiothreitol)|go:"GO:0072739"(response to anisomycin)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:0090734"(site of DNA damage)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902035"(positive regulation of hematopoietic stem cell proliferation)|go:"GO:2000819"(regulation of nucleotide-excision repair)|interpro:IPR002515(Zinc finger, C2HC-type)|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR036060|interpro:IPR036388|interpro:IPR040706|mint:O95251|rcsb pdb:5GK9|rcsb pdb:6MAJ|rcsb pdb:6MAK|reactome:R-HSA-3214847 - - comment:"author score: 136" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:brla9icZHYnZBj+2WtExolD2Z489606 rogid:K27pgvPEe1/+rZXYUkPfMY7PZMs9606 rigid:SBtv0PJkCBV4y4DOwAbMsoBx26A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96ST3 uniprotkb:Q86YI8 intact:EBI-347218|uniprotkb:Q8N8N4|uniprotkb:Q8NC83|uniprotkb:Q8WV18|uniprotkb:Q96L98|uniprotkb:Q9UFQ1|intact:EBI-28985143|ensembl:ENSP00000353622|ensembl:ENSP00000378402|ensembl:ENSP00000378403|uniprotkb:B2RNS5 intact:EBI-3925468|uniprotkb:Q9UJP2|uniprotkb:Q59FB6|uniprotkb:Q5TH65|uniprotkb:Q8N551|uniprotkb:B3KUQ7|ensembl:ENSP00000366876 psi-mi:sin3a_human(display_long)|uniprotkb:SIN3A(gene name)|psi-mi:SIN3A(display_short)|uniprotkb:Transcriptional corepressor Sin3a(gene name synonym)|uniprotkb:Histone deacetylase complex subunit Sin3a(gene name synonym) psi-mi:phf13_human(display_long)|uniprotkb:PHF13(gene name)|psi-mi:PHF13(display_short)|uniprotkb:Survival time-associated PHD finger protein in ovarian cancer 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25482328|imex:IM-26985-497 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006720528.1|ensembl:ENSG00000169375(gene)|ensembl:ENST00000360439(transcript)|ensembl:ENST00000394947(transcript)|ensembl:ENST00000394949(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007568"(aging)|go:"GO:0010817"(regulation of hormone levels)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0031937"(obsolete positive regulation of chromatin silencing)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0051595"(response to methylglyoxal)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1901675"(negative regulation of histone H3-K27 acetylation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR003822(Paired amphipathic helix)|interpro:IPR013194(Histone deacetylase interacting)|interpro:IPR031693|interpro:IPR036600|interpro:IPR037969|interpro:IPR039774|mint:Q96ST3|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-427413|reactome:R-HSA-8936459|reactome:R-HSA-9022538|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9022702|rcsb pdb:1PO4|reactome:R-HSA-9615017|reactome:R-HSA-9707564|reactome:R-HSA-983231|refseq:XP_006720529.1|refseq:XP_006720530.1|refseq:NP_001138829.1|refseq:NP_001138830.1|refseq:NP_056292.1|ensembl:ENSP00000353622|ensembl:ENSP00000378402|ensembl:ENSP00000378403|dip:DIP-31515N refseq:NP_722519.2|ensembl:ENSG00000116273(gene)|ensembl:ENST00000377648(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051301"(cell division)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR041947|mint:Q86YI8|rcsb pdb:3O70|rcsb pdb:3O7A - comment:"author score: 13" - figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pO/FziDcMNQRfy6ePi6eNKELXVM9606 rogid:srKPJn9CZJxhg8kNezGDdiz1GDw9606 rigid:L6vski2E6JD/bCUzC7Y3mx2KBI0 false - tandem tag:n-n - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUB8 uniprotkb:Q86U86 intact:EBI-716462|uniprotkb:Q2YDA3|uniprotkb:Q9BXD2|uniprotkb:Q53HG8|uniprotkb:Q9NV26|ensembl:ENSP00000341805 intact:EBI-637807|uniprotkb:Q9H2T3|uniprotkb:Q9H2T4|uniprotkb:Q9H2T5|uniprotkb:Q9H301|uniprotkb:Q9H314|uniprotkb:A1L381|uniprotkb:A1L382|uniprotkb:A4FUJ7|uniprotkb:Q1RMD1|uniprotkb:Q1RMD2|uniprotkb:Q96MS2|ensembl:ENSP00000296302 psi-mi:phf10_human(display_long)|uniprotkb:XAP135(gene name synonym)|uniprotkb:PHF10(gene name)|psi-mi:PHF10(display_short)|uniprotkb:BAF45A(gene name synonym)|uniprotkb:BRG1-associated factor 45a(gene name synonym) psi-mi:pb1_human(display_long)|uniprotkb:Polybromo-1D(gene name synonym)|uniprotkb:BRG1-associated factor 180(gene name synonym)|uniprotkb:PBRM1(gene name)|psi-mi:PBRM1(display_short)|uniprotkb:PB1(gene name synonym)|uniprotkb:BAF180(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482286|imex:IM-26985-195 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060758.2|refseq:NP_579866.2|ensembl:ENSG00000130024(gene)|ensembl:ENST00000339209(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071564"(npBAF complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR038045|mint:Q8WUB8 refseq:NP_060783.3|ensembl:ENSG00000163939(gene)|ensembl:ENST00000296302(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016586"(RSC-type complex)|go:"GO:0043044"|interpro:IPR001025(Bromo adjacent region)|interpro:IPR001487(Bromodomain)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR018359|interpro:IPR036427|interpro:IPR036910|interpro:IPR037382|interpro:IPR037968|interpro:IPR043151|mint:Q86U86|rcsb pdb:2KTB|rcsb pdb:3G0J|rcsb pdb:3HMF|rcsb pdb:3IU5|rcsb pdb:3IU6|rcsb pdb:3K2J|rcsb pdb:3LJW|rcsb pdb:3MB4|rcsb pdb:3TLP|rcsb pdb:4Q0N|rcsb pdb:4Q0O|rcsb pdb:4Y03|rcsb pdb:5E7D|rcsb pdb:5FH6|rcsb pdb:5FH7|rcsb pdb:5FH8|rcsb pdb:5HRV|rcsb pdb:5HRW|rcsb pdb:5HRX|rcsb pdb:5II1|rcsb pdb:5II2|rcsb pdb:5IID|rcsb pdb:6OXB|rcsb pdb:6ZN6|rcsb pdb:6ZNV|rcsb pdb:6ZS3|rcsb pdb:6ZS4|reactome:R-HSA-3214858|reactome:R-HSA-8939243|dip:DIP-33045N|refseq:XP_016862237.1|refseq:XP_016862238.1|refseq:XP_016862239.1|refseq:XP_016862246.1|refseq:XP_016862247.1|refseq:NP_851385.1 - - comment:"author score: 30" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QppOFkomM0Lm/7EjW4Fov8NhB049606 rogid:nJp9kwLE9qxj6DcyEO8dUok6k/Q9606 rigid:1I08gBJxqy3nSjJrYQ55mQy/rD4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUB8 uniprotkb:Q68CP9 intact:EBI-716462|uniprotkb:Q2YDA3|uniprotkb:Q9BXD2|uniprotkb:Q53HG8|uniprotkb:Q9NV26|ensembl:ENSP00000341805 intact:EBI-637818|uniprotkb:Q15KG9|uniprotkb:Q5EB51|uniprotkb:Q645I3|uniprotkb:Q6ZRY5|uniprotkb:Q7Z3I5|uniprotkb:Q86T28|uniprotkb:Q96SJ6|uniprotkb:Q9HCL5|ensembl:ENSP00000335044 psi-mi:phf10_human(display_long)|uniprotkb:XAP135(gene name synonym)|uniprotkb:PHF10(gene name)|psi-mi:PHF10(display_short)|uniprotkb:BAF45A(gene name synonym)|uniprotkb:BRG1-associated factor 45a(gene name synonym) psi-mi:arid2_human(display_long)|uniprotkb:BRG1-associated factor 200(gene name synonym)|uniprotkb:Zinc finger protein with activation potential(gene name synonym)|uniprotkb:Zipzap/p200(gene name synonym)|uniprotkb:ARID2(gene name)|psi-mi:ARID2(display_short)|uniprotkb:KIAA1557(gene name synonym)|uniprotkb:BAF200(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482286|imex:IM-26985-195 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060758.2|refseq:NP_579866.2|ensembl:ENSG00000130024(gene)|ensembl:ENST00000339209(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071564"(npBAF complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR038045|mint:Q8WUB8 refseq:NP_689854.2|ensembl:ENSG00000189079(gene)|ensembl:ENST00000334344(transcript)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042592"(homeostatic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048568"(embryonic organ development)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003150(DNA-binding RFX)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR036388|interpro:IPR036390|interpro:IPR036431|mint:Q68CP9|reactome:R-HSA-3214858|reactome:R-HSA-8939243|dip:DIP-33391N|refseq:NP_001334768.1|ensembl:ENSP00000335044 - - comment:"author score: 42" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QppOFkomM0Lm/7EjW4Fov8NhB049606 rogid:7AJ6PqICERVZS+s3sZBIBODzs/I9606 rigid:1I08gBJxqy3nSjJrYQ55mQy/rD4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUB8 uniprotkb:Q5RKV6 intact:EBI-716462|uniprotkb:Q2YDA3|uniprotkb:Q9BXD2|uniprotkb:Q53HG8|uniprotkb:Q9NV26|ensembl:ENSP00000341805 intact:EBI-2841747|ensembl:ENSP00000398597 psi-mi:phf10_human(display_long)|uniprotkb:XAP135(gene name synonym)|uniprotkb:PHF10(gene name)|psi-mi:PHF10(display_short)|uniprotkb:BAF45A(gene name synonym)|uniprotkb:BRG1-associated factor 45a(gene name synonym) psi-mi:exos6_human(display_long)|uniprotkb:EXOSC6(gene name)|psi-mi:EXOSC6(display_short)|uniprotkb:MTR3(gene name synonym)|uniprotkb:Exosome component 6(gene name synonym)|uniprotkb:mRNA transport regulator 3 homolog(gene name synonym)|uniprotkb:p11(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482286|imex:IM-26985-195 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060758.2|refseq:NP_579866.2|ensembl:ENSG00000130024(gene)|ensembl:ENST00000339209(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071564"(npBAF complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR038045|mint:Q8WUB8 refseq:NP_478126.1|ensembl:ENSG00000223496(gene)|ensembl:ENST00000435634(transcript)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0045006"(DNA deamination)|go:"GO:0045190"(isotype switching)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|interpro:IPR020568|interpro:IPR027408|interpro:IPR036345|mint:Q5RKV6|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|dip:DIP-61038N - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QppOFkomM0Lm/7EjW4Fov8NhB049606 rogid:tHH05GXmmH4GgRjtChjaGSLJ7Cc9606 rigid:1I08gBJxqy3nSjJrYQ55mQy/rD4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUB8 uniprotkb:P51532 intact:EBI-716462|uniprotkb:Q2YDA3|uniprotkb:Q9BXD2|uniprotkb:Q53HG8|uniprotkb:Q9NV26|ensembl:ENSP00000341805 intact:EBI-302489|uniprotkb:O95052|uniprotkb:Q9HBD3|uniprotkb:B1A8Z4|uniprotkb:B1A8Z5|uniprotkb:B1A8Z6|uniprotkb:B1A8Z7|uniprotkb:E9PBR8|ensembl:ENSP00000343896|ensembl:ENSP00000395654 psi-mi:phf10_human(display_long)|uniprotkb:XAP135(gene name synonym)|uniprotkb:PHF10(gene name)|psi-mi:PHF10(display_short)|uniprotkb:BAF45A(gene name synonym)|uniprotkb:BRG1-associated factor 45a(gene name synonym) psi-mi:smca4_human(display_long)|uniprotkb:SMARCA4(gene name)|psi-mi:SMARCA4(display_short)|uniprotkb:BRG1(gene name synonym)|uniprotkb:SNF2B(gene name synonym)|uniprotkb:SNF2L4(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA4(gene name synonym)|uniprotkb:SNF2-beta(gene name synonym)|uniprotkb:BAF190A(gene name synonym)|uniprotkb:Mitotic growth and transcription activator(gene name synonym)|uniprotkb:Protein BRG-1(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4(gene name synonym)|uniprotkb:Protein brahma homolog 1(gene name synonym)|uniprotkb:BRG1-associated factor 190A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482286|imex:IM-26985-195 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060758.2|refseq:NP_579866.2|ensembl:ENSG00000130024(gene)|ensembl:ENST00000339209(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071564"(npBAF complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR038045|mint:Q8WUB8 refseq:NP_001122316.1|refseq:NP_003063.2|refseq:NP_001122317.1|refseq:NP_001122318.1|refseq:NP_001122319.1|refseq:NP_001122320.1|dip:DIP-24249N|refseq:XP_016882654.1|refseq:XP_016882655.1|refseq:XP_016882656.1|refseq:XP_016882657.1|ensembl:ENSG00000127616(gene)|ensembl:ENST00000344626(transcript)|ensembl:ENST00000429416(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0002039"(p53 binding)|go:"GO:0003407"(neural retina development)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030100|interpro:IPR036427|interpro:IPR037259|interpro:IPR038718|mint:P51532|rcsb pdb:2GRC|rcsb pdb:2H60|rcsb pdb:3UVD|rcsb pdb:5DKD|rcsb pdb:5EA1|rcsb pdb:6BGH|rcsb pdb:6HR2|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6SY2|rcsb pdb:6ZS2|reactome:R-HSA-1266695|reactome:R-HSA-201722|reactome:R-HSA-3214858|reactome:R-HSA-3247509|reactome:R-HSA-8939243|reactome:R-HSA-9619665 - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QppOFkomM0Lm/7EjW4Fov8NhB049606 rogid:Ztr+2IXfAxueSUaNYG2A47HoMes9606 rigid:1I08gBJxqy3nSjJrYQ55mQy/rD4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUB8 uniprotkb:Q13868 intact:EBI-716462|uniprotkb:Q2YDA3|uniprotkb:Q9BXD2|uniprotkb:Q53HG8|uniprotkb:Q9NV26|ensembl:ENSP00000341805 intact:EBI-301735|uniprotkb:Q9NUY4|uniprotkb:A3KFL3|ensembl:ENSP00000361433|uniprotkb:A3KFL4|uniprotkb:B4DKK6 psi-mi:phf10_human(display_long)|uniprotkb:XAP135(gene name synonym)|uniprotkb:PHF10(gene name)|psi-mi:PHF10(display_short)|uniprotkb:BAF45A(gene name synonym)|uniprotkb:BRG1-associated factor 45a(gene name synonym) psi-mi:exos2_human(display_long)|uniprotkb:EXOSC2(gene name)|psi-mi:EXOSC2(display_short)|uniprotkb:RRP4(gene name synonym)|uniprotkb:Ribosomal RNA-processing protein 4(gene name synonym)|uniprotkb:Exosome component 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482286|imex:IM-26985-195 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060758.2|refseq:NP_579866.2|ensembl:ENSG00000130024(gene)|ensembl:ENST00000339209(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071564"(npBAF complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR038045|mint:Q8WUB8 refseq:NP_055100.2|ensembl:ENSG00000130713(gene)|ensembl:ENST00000372358(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0071034"(CUT catabolic process)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071049"|go:"GO:0071051"(polyadenylation-dependent snoRNA 3'-end processing)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR025721|interpro:IPR026699|interpro:IPR036612|mint:Q13868|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|refseq:NP_001269638.1|dip:DIP-31264N|refseq:NP_001269637.1 - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QppOFkomM0Lm/7EjW4Fov8NhB049606 rogid:Lpl4OBbEYV2DRbYzLCPvbQdtaro9606 rigid:1I08gBJxqy3nSjJrYQ55mQy/rD4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUB8 uniprotkb:Q8TAQ2 intact:EBI-716462|uniprotkb:Q2YDA3|uniprotkb:Q9BXD2|uniprotkb:Q53HG8|uniprotkb:Q9NV26|ensembl:ENSP00000341805 intact:EBI-357418|ensembl:ENSP00000267064|uniprotkb:Q92923|uniprotkb:Q96E12|uniprotkb:Q96GY4|intact:EBI-1759986|intact:EBI-1965079|uniprotkb:F8VTJ5|uniprotkb:Q59GV3 psi-mi:phf10_human(display_long)|uniprotkb:XAP135(gene name synonym)|uniprotkb:PHF10(gene name)|psi-mi:PHF10(display_short)|uniprotkb:BAF45A(gene name synonym)|uniprotkb:BRG1-associated factor 45a(gene name synonym) psi-mi:smrc2_human(display_long)|uniprotkb:SMARCC2(gene name)|psi-mi:SMARCC2(display_short)|uniprotkb:BAF170(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2(gene name synonym)|uniprotkb:SWI/SNF complex 170 kDa subunit(gene name synonym)|uniprotkb:BRG1-associated factor 170(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482286|imex:IM-26985-195 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060758.2|refseq:NP_579866.2|ensembl:ENSG00000130024(gene)|ensembl:ENST00000339209(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071564"(npBAF complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR038045|mint:Q8WUB8 ensembl:ENSG00000139613(gene)|ensembl:ENST00000267064(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR000953(Chromo domain)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR032448|interpro:IPR032450|interpro:IPR032451|interpro:IPR036388|interpro:IPR036420|interpro:IPR038044|mint:Q8TAQ2|rcsb pdb:6KAG|rcsb pdb:6LTH|rcsb pdb:6LTJ|reactome:R-HSA-3214858|reactome:R-HSA-8939243|refseq:NP_003066.2|refseq:NP_001123892.1|refseq:NP_620706.1|refseq:NP_001317217.1|dip:DIP-27611N - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QppOFkomM0Lm/7EjW4Fov8NhB049606 rogid:60gIB3J1YI/FzqVCzdoSg1Oj3ME9606 rigid:1I08gBJxqy3nSjJrYQ55mQy/rD4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUB8 uniprotkb:O96019 intact:EBI-716462|uniprotkb:Q2YDA3|uniprotkb:Q9BXD2|uniprotkb:Q53HG8|uniprotkb:Q9NV26|ensembl:ENSP00000341805 intact:EBI-355018|uniprotkb:Q8TAE5|uniprotkb:Q9BVS8|uniprotkb:Q9H0W6|uniprotkb:B3KMN1|uniprotkb:D3DNR9|ensembl:ENSP00000397552 psi-mi:phf10_human(display_long)|uniprotkb:XAP135(gene name synonym)|uniprotkb:PHF10(gene name)|psi-mi:PHF10(display_short)|uniprotkb:BAF45A(gene name synonym)|uniprotkb:BRG1-associated factor 45a(gene name synonym) psi-mi:acl6a_human(display_long)|uniprotkb:53 kDa BRG1-associated factor A(gene name synonym)|uniprotkb:Actin-related protein Baf53a(gene name synonym)|uniprotkb:ArpNbeta(gene name synonym)|uniprotkb:BAF53A(gene name synonym)|uniprotkb:ACTL6A(gene name)|psi-mi:ACTL6A(display_short)|uniprotkb:BAF53(gene name synonym)|uniprotkb:INO80K(gene name synonym)|uniprotkb:INO80 complex subunit K(gene name synonym)|uniprotkb:BRG1-associated factor 53A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482286|imex:IM-26985-195 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060758.2|refseq:NP_579866.2|ensembl:ENSG00000130024(gene)|ensembl:ENST00000339209(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071564"(npBAF complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR038045|mint:Q8WUB8 refseq:NP_004292.1|refseq:NP_817126.1|refseq:NP_829888.1|ensembl:ENSG00000136518(gene)|ensembl:ENST00000429709(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0003407"(neural retina development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0021510"(spinal cord development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043044"|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0071564"(npBAF complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR043129|mint:O96019|rcsb pdb:6LTJ|reactome:R-HSA-3214847|reactome:R-HSA-3214858|go:"GO:0000785"(chromatin)|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8939243|ensembl:ENST00000392662|ensembl:ENSP00000376430|ensembl:ENSP00000397552|ensembl:ENST00000450518|ensembl:ENSP00000394014|dip:DIP-27565N - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QppOFkomM0Lm/7EjW4Fov8NhB049606 rogid:FV8zvQxf2aeHbwFNUpo9JOpj5U49606 rigid:1I08gBJxqy3nSjJrYQ55mQy/rD4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUB8 uniprotkb:Q92922 intact:EBI-716462|uniprotkb:Q2YDA3|uniprotkb:Q9BXD2|uniprotkb:Q53HG8|uniprotkb:Q9NV26|ensembl:ENSP00000341805 intact:EBI-355653|uniprotkb:Q6P172|uniprotkb:Q8IWH2|uniprotkb:Q17RS0|ensembl:ENSP00000254480 psi-mi:phf10_human(display_long)|uniprotkb:XAP135(gene name synonym)|uniprotkb:PHF10(gene name)|psi-mi:PHF10(display_short)|uniprotkb:BAF45A(gene name synonym)|uniprotkb:BRG1-associated factor 45a(gene name synonym) psi-mi:smrc1_human(display_long)|uniprotkb:SMARCC1(gene name)|psi-mi:SMARCC1(display_short)|uniprotkb:BAF155(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1(gene name synonym)|uniprotkb:SWI/SNF complex 155 kDa subunit(gene name synonym)|uniprotkb:BRG1-associated factor 155(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482286|imex:IM-26985-195 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060758.2|refseq:NP_579866.2|ensembl:ENSG00000130024(gene)|ensembl:ENST00000339209(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071564"(npBAF complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR038045|mint:Q8WUB8 refseq:NP_003065.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR000953(Chromo domain)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR030087|interpro:IPR032448|interpro:IPR032450|interpro:IPR032451|interpro:IPR036388|interpro:IPR036420|mint:Q92922|rcsb pdb:2YUS|rcsb pdb:5GJK|rcsb pdb:6KZ7|rcsb pdb:6YXO|rcsb pdb:6YXP|reactome:R-HSA-3214858|reactome:R-HSA-8939243|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|ensembl:ENSG00000173473(gene)|ensembl:ENST00000254480(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001741"(XY body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030850"(prostate gland development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|ensembl:ENSP00000254480|dip:DIP-27545N|dip:DIP-33044N - - comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QppOFkomM0Lm/7EjW4Fov8NhB049606 rogid:Uv0bjPkUICLtOXJcETUXDTLIQhY9606 rigid:1I08gBJxqy3nSjJrYQ55mQy/rD4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUB8 uniprotkb:Q06265 intact:EBI-716462|uniprotkb:Q2YDA3|uniprotkb:Q9BXD2|uniprotkb:Q53HG8|uniprotkb:Q9NV26|ensembl:ENSP00000341805 intact:EBI-347966|ensembl:ENSP00000243498|uniprotkb:Q12883|uniprotkb:Q86Y41|uniprotkb:Q86Y48|uniprotkb:Q4W5P5 psi-mi:phf10_human(display_long)|uniprotkb:XAP135(gene name synonym)|uniprotkb:PHF10(gene name)|psi-mi:PHF10(display_short)|uniprotkb:BAF45A(gene name synonym)|uniprotkb:BRG1-associated factor 45a(gene name synonym) psi-mi:exos9_human(display_long)|uniprotkb:EXOSC9(gene name)|psi-mi:EXOSC9(display_short)|uniprotkb:PMSCL1(gene name synonym)|uniprotkb:Exosome component 9(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 1(gene name synonym)|uniprotkb:Autoantigen PM/Scl 1(gene name synonym)|uniprotkb:Polymyositis/scleroderma autoantigen 75 kDa(gene name synonym)|uniprotkb:P75 polymyositis-scleroderma overlap syndrome-associated autoantigen(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482286|imex:IM-26985-195 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060758.2|refseq:NP_579866.2|ensembl:ENSG00000130024(gene)|ensembl:ENST00000339209(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071564"(npBAF complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR038045|mint:Q8WUB8 go:"GO:0000178"("exosome (RNase complex)")|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000467"("exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006955"(immune response)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0034473"(U1 snRNA 3'-end processing)|go:"GO:0034475"(U4 snRNA 3'-end processing)|go:"GO:0034476"(U5 snRNA 3'-end processing)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0000177"("cytoplasmic exosome (RNase complex)")|go:"GO:0043928"(exonucleolytic catabolism of deadenylated mRNA)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071038"(nuclear polyadenylation-dependent tRNA catabolic process)|go:"GO:0071042"(nuclear polyadenylation-dependent mRNA catabolic process)|interpro:IPR001247(Exoribonuclease, phosphorolytic domain 1)|go:"GO:0071035"(nuclear polyadenylation-dependent rRNA catabolic process)|interpro:IPR015847(Exoribonuclease, phosphorolytic domain 2)|interpro:IPR020568|interpro:IPR027408|interpro:IPR033100|interpro:IPR036345|mint:Q06265|rcsb pdb:2NN6|rcsb pdb:6D6Q|rcsb pdb:6D6R|rcsb pdb:6H25|reactome:R-HSA-380994|reactome:R-HSA-429958|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-450604|reactome:R-HSA-6791226|ensembl:ENSG00000123737(gene)|ensembl:ENST00000243498(transcript)|go:"GO:0000175"(3'-5'-exoribonuclease activity)|go:"GO:0000176"("nuclear exosome (RNase complex)")|refseq:NP_001029366.1|refseq:NP_005024.2|dip:DIP-31286N - - comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QppOFkomM0Lm/7EjW4Fov8NhB049606 rogid:COzGZISdlfGlht1FhyxPhzbV9hY9606 rigid:1I08gBJxqy3nSjJrYQ55mQy/rD4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUB8 uniprotkb:Q96GM5 intact:EBI-716462|uniprotkb:Q2YDA3|uniprotkb:Q9BXD2|uniprotkb:Q53HG8|uniprotkb:Q9NV26|ensembl:ENSP00000341805 intact:EBI-358489|intact:EBI-1760001|ensembl:ENSP00000378414|uniprotkb:Q92924|uniprotkb:Q9Y635|intact:EBI-1965109|uniprotkb:A6NN27|intact:EBI-28976725 psi-mi:phf10_human(display_long)|uniprotkb:XAP135(gene name synonym)|uniprotkb:PHF10(gene name)|psi-mi:PHF10(display_short)|uniprotkb:BAF45A(gene name synonym)|uniprotkb:BRG1-associated factor 45a(gene name synonym) psi-mi:smrd1_human(display_long)|uniprotkb:SMARCD1(gene name)|psi-mi:SMARCD1(display_short)|uniprotkb:BAF60A(gene name synonym)|uniprotkb:SWI/SNF complex 60 kDa subunit(gene name synonym)|uniprotkb:60 kDa BRG-1/Brm-associated factor subunit A(gene name synonym)|uniprotkb:BRG1-associated factor 60A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482286|imex:IM-26985-195 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060758.2|refseq:NP_579866.2|ensembl:ENSG00000130024(gene)|ensembl:ENST00000339209(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071564"(npBAF complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR038045|mint:Q8WUB8 ensembl:ENSG00000066117(gene)|ensembl:ENST00000394963(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048096"|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071564"(npBAF complex)|refseq:NP_003067.3|refseq:NP_620710.2|ensembl:ENST00000381513|ensembl:ENSP00000370924|ensembl:ENSP00000378414|go:"GO:0071565"(nBAF complex)|interpro:IPR003121(SWIB/MDM2)|interpro:IPR019835|interpro:IPR036885|interpro:IPR038041|mint:Q96GM5|rcsb pdb:6LTH|rcsb pdb:6LTJ|reactome:R-HSA-3214858|reactome:R-HSA-8939243|dip:DIP-33390N - - comment:"author score: 29" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QppOFkomM0Lm/7EjW4Fov8NhB049606 rogid:cwqYnl+J8glG8YjW1ps77Dd105Y9606 rigid:1I08gBJxqy3nSjJrYQ55mQy/rD4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUB8 uniprotkb:Q92925 intact:EBI-716462|uniprotkb:Q2YDA3|uniprotkb:Q9BXD2|uniprotkb:Q53HG8|uniprotkb:Q9NV26|ensembl:ENSP00000341805 intact:EBI-358441|uniprotkb:Q7L2I6|uniprotkb:Q9UHZ1|uniprotkb:A5PLL5|uniprotkb:A6NNQ7|uniprotkb:B4DV56|uniprotkb:B4E1R6|ensembl:ENSP00000392617 psi-mi:phf10_human(display_long)|uniprotkb:XAP135(gene name synonym)|uniprotkb:PHF10(gene name)|psi-mi:PHF10(display_short)|uniprotkb:BAF45A(gene name synonym)|uniprotkb:BRG1-associated factor 45a(gene name synonym) psi-mi:smrd2_human(display_long)|uniprotkb:PRO2451(orf name)|uniprotkb:SMARCD2(gene name)|psi-mi:SMARCD2(display_short)|uniprotkb:BAF60B(gene name synonym)|uniprotkb:60 kDa BRG-1/Brm-associated factor subunit B(gene name synonym)|uniprotkb:BRG1-associated factor 60B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482286|imex:IM-26985-195 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060758.2|refseq:NP_579866.2|ensembl:ENSG00000130024(gene)|ensembl:ENST00000339209(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071564"(npBAF complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR038045|mint:Q8WUB8 refseq:NP_001091896.1|dip:DIP-31182N|refseq:NP_001317369.1|ensembl:ENSG00000108604(gene)|ensembl:ENST00000448276(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR003121(SWIB/MDM2)|interpro:IPR019835|interpro:IPR030090|interpro:IPR036885|mint:Q92925|reactome:R-HSA-3214858|reactome:R-HSA-8939243 - - comment:"author score: 34" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QppOFkomM0Lm/7EjW4Fov8NhB049606 rogid:n6YHBJ+cqEmVcXwMYsTZGOfL86A9606 rigid:1I08gBJxqy3nSjJrYQ55mQy/rD4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WUB8 uniprotkb:Q9NPI1 intact:EBI-716462|uniprotkb:Q2YDA3|uniprotkb:Q9BXD2|uniprotkb:Q53HG8|uniprotkb:Q9NV26|ensembl:ENSP00000341805 intact:EBI-711221|uniprotkb:Q4VC09|uniprotkb:Q8N2L9|uniprotkb:Q96KA4|uniprotkb:Q9BV48|uniprotkb:Q9UH59|intact:EBI-2560548|ensembl:ENSP00000378180 psi-mi:phf10_human(display_long)|uniprotkb:XAP135(gene name synonym)|uniprotkb:PHF10(gene name)|psi-mi:PHF10(display_short)|uniprotkb:BAF45A(gene name synonym)|uniprotkb:BRG1-associated factor 45a(gene name synonym) psi-mi:brd7_human(display_long)|uniprotkb:75 kDa bromodomain protein(gene name synonym)|uniprotkb:Protein CELTIX-1(gene name synonym)|uniprotkb:BRD7(gene name)|psi-mi:BRD7(display_short)|uniprotkb:BP75(gene name synonym)|uniprotkb:CELTIX1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482286|imex:IM-26985-195 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060758.2|refseq:NP_579866.2|ensembl:ENSG00000130024(gene)|ensembl:ENST00000339209(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071564"(npBAF complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR038045|mint:Q8WUB8 refseq:NP_001167455.1|refseq:NP_037395.2|dip:DIP-32509N|ensembl:ENSG00000166164(gene)|ensembl:ENST00000394688(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001487(Bromodomain)|interpro:IPR021900|interpro:IPR036427|mint:Q9NPI1|rcsb pdb:2I7K|rcsb pdb:5MQ1|rcsb pdb:6PPA|rcsb pdb:6V0Q|rcsb pdb:6V16|rcsb pdb:6V17|rcsb pdb:6V1E|rcsb pdb:6V1F|rcsb pdb:6V1H|reactome:R-HSA-6804758 - - comment:"author score: 42" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QppOFkomM0Lm/7EjW4Fov8NhB049606 rogid:F1N3XsdbpPy8TgHdMLSmnhdKNYs9606 rigid:1I08gBJxqy3nSjJrYQ55mQy/rD4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23760 uniprotkb:Q8N6M3 intact:EBI-1167564|uniprotkb:Q16448|uniprotkb:Q53T90|uniprotkb:Q6GSJ9|uniprotkb:Q86UQ2|uniprotkb:Q86UQ3|uniprotkb:Q494Z3|uniprotkb:Q494Z4|uniprotkb:G5E9C1|ensembl:ENSP00000343052 intact:EBI-11722638|uniprotkb:A1L492|uniprotkb:B9EGQ4|uniprotkb:Q5TE59|uniprotkb:Q9H3Y1|ensembl:ENSP00000380037 psi-mi:pax3_human(display_long)|uniprotkb:PAX3(gene name)|psi-mi:PAX3(display_short)|uniprotkb:HUP2(gene name synonym)|uniprotkb:HuP2(gene name synonym) psi-mi:fitm2_human(display_long)|uniprotkb:Fat storage-inducing transmembrane protein 2(gene name synonym)|uniprotkb:FITM2(gene name)|psi-mi:FITM2(display_short)|uniprotkb:C20orf142(gene name synonym)|uniprotkb:FIT2(gene name synonym)|uniprotkb:Fat-inducing protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482229|imex:IM-26985-495 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000429.2|refseq:NP_039230.1|refseq:NP_852122.1|refseq:NP_001120838.1|refseq:NP_852123.1|refseq:NP_852124.1|refseq:NP_852125.1|refseq:NP_852126.1|ensembl:ENSG00000135903(gene)|ensembl:ENST00000350526(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR022106|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565|mint:P23760|rcsb pdb:3CMY|reactome:R-HSA-3214847 refseq:NP_001073941.1|ensembl:ENSG00000197296(gene)|ensembl:ENST00000396825(transcript)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008654"(phospholipid biosynthetic process)|go:"GO:0010866"(regulation of triglyceride biosynthetic process)|go:"GO:0010890"(positive regulation of sequestering of triglyceride)|go:"GO:0010945"(CoA pyrophosphatase activity)|go:"GO:0017129"(triglyceride binding)|go:"GO:0019915"(lipid storage)|go:"GO:0019992"(diacylglycerol binding)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030730"(sequestering of triglyceride)|go:"GO:0034389"(lipid droplet organization)|go:"GO:0035356"(cellular triglyceride homeostasis)|go:"GO:0036115"(fatty-acyl-CoA catabolic process)|go:"GO:0055088"(lipid homeostasis)|go:"GO:0140042"(lipid droplet formation)|interpro:IPR019388|mint:Q8N6M3|reactome:R-HSA-8964572 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W/MFjTf3d4mRzCXRWgl0sk/mdX49606 rogid:u9+KyPWVwAP5y+ocBi3cYwwS1o49606 rigid:uXi79XFQL2FYImWOabR1VWj5GWk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23760 uniprotkb:P02461 intact:EBI-1167564|uniprotkb:Q16448|uniprotkb:Q53T90|uniprotkb:Q6GSJ9|uniprotkb:Q86UQ2|uniprotkb:Q86UQ3|uniprotkb:Q494Z3|uniprotkb:Q494Z4|uniprotkb:G5E9C1|ensembl:ENSP00000343052 intact:EBI-2431491|uniprotkb:P78429|uniprotkb:Q15112|uniprotkb:Q9UC90|uniprotkb:Q9UC91|uniprotkb:Q16403|uniprotkb:Q53S91|uniprotkb:Q541P8|uniprotkb:Q6LDB3|uniprotkb:Q6LDJ2|uniprotkb:Q6LDJ3|uniprotkb:Q7KZ56|uniprotkb:Q8N6U4|uniprotkb:Q9UC88|uniprotkb:Q9UC89|uniprotkb:D2JYH5|uniprotkb:R4N3C5|uniprotkb:V9GZI1|uniprotkb:D3DPH4|ensembl:ENSP00000304408 psi-mi:pax3_human(display_long)|uniprotkb:PAX3(gene name)|psi-mi:PAX3(display_short)|uniprotkb:HUP2(gene name synonym)|uniprotkb:HuP2(gene name synonym) psi-mi:co3a1_human(display_long)|uniprotkb:COL3A1(gene name)|psi-mi:COL3A1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482229|imex:IM-26985-495 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000429.2|refseq:NP_039230.1|refseq:NP_852122.1|refseq:NP_001120838.1|refseq:NP_852123.1|refseq:NP_852124.1|refseq:NP_852125.1|refseq:NP_852126.1|ensembl:ENSG00000135903(gene)|ensembl:ENST00000350526(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR022106|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565|mint:P23760|rcsb pdb:3CMY|reactome:R-HSA-3214847 refseq:NP_000081.1|dip:DIP-57177N|ensembl:ENSG00000168542(gene)|ensembl:ENST00000304636(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0002020"(protease binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005586"(collagen type III trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0009314"(response to radiation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030020"(extracellular matrix structural constituent conferring tensile strength)|go:"GO:0030168"(platelet activation)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0034097"(response to cytokine)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0042060"(wound healing)|go:"GO:0043588"(skin development)|go:"GO:0046872"(metal ion binding)|go:"GO:0048407"(platelet-derived growth factor binding)|go:"GO:0050777"(negative regulation of immune response)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0097435"(supramolecular fiber organization)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000885(Fibrillar collagen, C-terminal)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR008160(Collagen triple helix repeat)|mint:P02461|rcsb pdb:2V53|rcsb pdb:3DMW|rcsb pdb:4AE2|rcsb pdb:4AEJ|rcsb pdb:4AK3|rcsb pdb:4GYX|rcsb pdb:6FZV|rcsb pdb:6FZW|reactome:R-HSA-1442490|reactome:R-HSA-1474244|reactome:R-HSA-1650814|reactome:R-HSA-186797|reactome:R-HSA-198933|reactome:R-HSA-2022090|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-3000480|reactome:R-HSA-419037|reactome:R-HSA-8874081|reactome:R-HSA-8948216 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W/MFjTf3d4mRzCXRWgl0sk/mdX49606 rogid:mJwvNKDtUVF6OMwaeEO2xcjKYWE9606 rigid:uXi79XFQL2FYImWOabR1VWj5GWk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23760 uniprotkb:P08123 intact:EBI-1167564|uniprotkb:Q16448|uniprotkb:Q53T90|uniprotkb:Q6GSJ9|uniprotkb:Q86UQ2|uniprotkb:Q86UQ3|uniprotkb:Q494Z3|uniprotkb:Q494Z4|uniprotkb:G5E9C1|ensembl:ENSP00000343052 intact:EBI-983038|uniprotkb:P02464|uniprotkb:Q13897|uniprotkb:Q13997|ensembl:ENSP00000297268|uniprotkb:Q7Z5S6|uniprotkb:Q9UEB6|uniprotkb:Q9UEF9|uniprotkb:Q9UM83|uniprotkb:Q9UMI1|uniprotkb:Q9UML5|uniprotkb:Q9UMM6|uniprotkb:Q9UPH0|uniprotkb:Q13998|uniprotkb:Q14038|uniprotkb:Q14057|uniprotkb:Q15177|uniprotkb:Q15947|uniprotkb:Q16480|uniprotkb:Q16511 psi-mi:pax3_human(display_long)|uniprotkb:PAX3(gene name)|psi-mi:PAX3(display_short)|uniprotkb:HUP2(gene name synonym)|uniprotkb:HuP2(gene name synonym) psi-mi:co1a2_human(display_long)|uniprotkb:Alpha-2 type I collagen(gene name synonym)|uniprotkb:COL1A2(gene name)|psi-mi:COL1A2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482229|imex:IM-26985-495 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000429.2|refseq:NP_039230.1|refseq:NP_852122.1|refseq:NP_001120838.1|refseq:NP_852123.1|refseq:NP_852124.1|refseq:NP_852125.1|refseq:NP_852126.1|ensembl:ENSG00000135903(gene)|ensembl:ENST00000350526(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR022106|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565|mint:P23760|rcsb pdb:3CMY|reactome:R-HSA-3214847 ensembl:ENSG00000164692(gene)|ensembl:ENST00000297268(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001568"(blood vessel development)|go:"GO:0002020"(protease binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005584"(collagen type I trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0030020"(extracellular matrix structural constituent conferring tensile strength)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030282"(bone mineralization)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031012"(extracellular matrix)|go:"GO:0032963"(collagen metabolic process)|go:"GO:0042476"(odontogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048407"(platelet-derived growth factor binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070208"(protein heterotrimerization)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0085029"(extracellular matrix assembly)|interpro:IPR000885(Fibrillar collagen, C-terminal)|interpro:IPR008160(Collagen triple helix repeat)|mint:P08123|rcsb pdb:5CTD|rcsb pdb:5CTI|rcsb pdb:5CVA|rcsb pdb:6JEC|reactome:R-HSA-114604|reactome:R-HSA-1442490|reactome:R-HSA-1474244|reactome:R-HSA-1650814|reactome:R-HSA-198933|reactome:R-HSA-2022090|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-2214320|reactome:R-HSA-2243919|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-3000480|reactome:R-HSA-430116|reactome:R-HSA-6785807|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-8874081|reactome:R-HSA-8948216|refseq:NP_000080.2|dip:DIP-36079N - - comment:"author score: 28" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W/MFjTf3d4mRzCXRWgl0sk/mdX49606 rogid:vRxr0tOWziIyQf9or1gC6sDlN8I9606 rigid:uXi79XFQL2FYImWOabR1VWj5GWk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23760 uniprotkb:P68871 intact:EBI-1167564|uniprotkb:Q16448|uniprotkb:Q53T90|uniprotkb:Q6GSJ9|uniprotkb:Q86UQ2|uniprotkb:Q86UQ3|uniprotkb:Q494Z3|uniprotkb:Q494Z4|uniprotkb:G5E9C1|ensembl:ENSP00000343052 intact:EBI-715554|ensembl:ENSP00000333994|ensembl:ENSP00000494175|uniprotkb:P02023|uniprotkb:Q13852|uniprotkb:Q14481|uniprotkb:Q14510|uniprotkb:Q45KT0|uniprotkb:Q6FI08|uniprotkb:Q8IZI1|uniprotkb:Q9BX96|uniprotkb:Q9UCP8|uniprotkb:Q9UCP9|uniprotkb:A4GX73|uniprotkb:B2ZUE0|uniprotkb:Q549N7|uniprotkb:Q6R7N2|uniprotkb:Q9UCD6 psi-mi:pax3_human(display_long)|uniprotkb:PAX3(gene name)|psi-mi:PAX3(display_short)|uniprotkb:HUP2(gene name synonym)|uniprotkb:HuP2(gene name synonym) psi-mi:hbb_human(display_long)|uniprotkb:Hemoglobin beta chain(gene name synonym)|uniprotkb:Beta-globin(gene name synonym)|uniprotkb:HBB(gene name)|psi-mi:HBB(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482229|imex:IM-26985-495 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000429.2|refseq:NP_039230.1|refseq:NP_852122.1|refseq:NP_001120838.1|refseq:NP_852123.1|refseq:NP_852124.1|refseq:NP_852125.1|refseq:NP_852126.1|ensembl:ENSG00000135903(gene)|ensembl:ENST00000350526(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR022106|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565|mint:P23760|rcsb pdb:3CMY|reactome:R-HSA-3214847 ensembl:ENSG00000244734(gene)|ensembl:ENST00000335295(transcript)|ensembl:ENST00000647020(transcript)|refseq:NP_000509.1|rcsb pdb:1XZ4|rcsb pdb:1XZ2|rcsb pdb:1XZ5|rcsb pdb:1XZ7|rcsb pdb:1XZU|rcsb pdb:1XZV|rcsb pdb:1Y09|rcsb pdb:1Y0A|rcsb pdb:1Y0C|rcsb pdb:1Y0D|rcsb pdb:1Y0T|rcsb pdb:1Y0W|rcsb pdb:1Y22|rcsb pdb:1Y2Z|rcsb pdb:1Y31|rcsb pdb:1Y35|rcsb pdb:1Y45|rcsb pdb:1Y46|rcsb pdb:1Y4B|rcsb pdb:1Y4F|rcsb pdb:1Y4G|rcsb pdb:1Y4P|rcsb pdb:1Y4Q|rcsb pdb:1Y4R|rcsb pdb:1Y4V|rcsb pdb:1Y5F|rcsb pdb:1Y5J|rcsb pdb:1Y5K|rcsb pdb:1Y7C|rcsb pdb:1Y7D|rcsb pdb:1Y7G|rcsb pdb:1Y7Z|rcsb pdb:1Y83|rcsb pdb:1Y85|rcsb pdb:1Y8W|rcsb pdb:1YDZ|rcsb pdb:1YE0|rcsb pdb:1YE1|rcsb pdb:1YE2|rcsb pdb:1YEN|rcsb pdb:1YEO|rcsb pdb:1YEQ|rcsb pdb:1YEU|rcsb pdb:1YEV|rcsb pdb:1YFF|rcsb pdb:1YG5|rcsb pdb:1YGD|rcsb pdb:1YGF|rcsb pdb:1YH9|rcsb pdb:1YHE|rcsb pdb:1YHR|rcsb pdb:1YIE|rcsb pdb:1YIH|rcsb pdb:1YVQ|rcsb pdb:1YZI|rcsb pdb:2D5Z|rcsb pdb:2D60|rcsb pdb:2DN1|rcsb pdb:2DN2|rcsb pdb:2DN3|rcsb pdb:2DXM|rcsb pdb:1YVT|rcsb pdb:2H35|rcsb pdb:2HBC|rcsb pdb:2HBD|rcsb pdb:2HBE|rcsb pdb:2HBF|rcsb pdb:2HBS|rcsb pdb:2HCO|rcsb pdb:2HHB|rcsb pdb:2HHD|rcsb pdb:2HHE|rcsb pdb:2M6Z|rcsb pdb:2W6V|rcsb pdb:2W72|rcsb pdb:2YRS|rcsb pdb:3B75|rcsb pdb:3D17|rcsb pdb:3D7O|rcsb pdb:3DUT|rcsb pdb:3HHB|rcsb pdb:3IC0|rcsb pdb:3IC2|rcsb pdb:3HXN|rcsb pdb:3KMF|rcsb pdb:3NL7|rcsb pdb:3NMM|rcsb pdb:3ODQ|rcsb pdb:3ONZ|rcsb pdb:3OO4|rcsb pdb:3OO5|rcsb pdb:3P5Q|rcsb pdb:3QJB|rcsb pdb:3QJC|rcsb pdb:3QJD|rcsb pdb:3QJE|rcsb pdb:3R5I|rcsb pdb:3S65|rcsb pdb:3S66|rcsb pdb:3SZK|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0015671"(oxygen transport)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0030185"(nitric oxide transport)|go:"GO:0030492"(hemoglobin binding)|go:"GO:0031721"(hemoglobin alpha binding)|go:"GO:0031838"(haptoglobin-hemoglobin complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043177"(organic acid binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070293"(renal absorption)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0098869"(cellular oxidant detoxification)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000971(Globin, subset)|interpro:IPR002337(Haemoglobin, beta)|interpro:IPR009050(Globin-like)|interpro:IPR012292(Globin)|mint:P68871|rcsb pdb:1A00|rcsb pdb:1A01|rcsb pdb:1A0U|rcsb pdb:1A0Z|rcsb pdb:1A3N|go:"GO:0072562"(blood microparticle)|rcsb pdb:1A3O|rcsb pdb:1ABW|rcsb pdb:1ABY|rcsb pdb:1AJ9|rcsb pdb:1B86|rcsb pdb:1BAB|rcsb pdb:1BBB|rcsb pdb:1BIJ|rcsb pdb:1BUW|rcsb pdb:1BZ0|rcsb pdb:1BZ1|rcsb pdb:1BZZ|rcsb pdb:1C7B|rcsb pdb:1C7C|rcsb pdb:1C7D|rcsb pdb:1CBL|rcsb pdb:1CBM|rcsb pdb:1CH4|rcsb pdb:1CLS|rcsb pdb:1CMY|rcsb pdb:1COH|rcsb pdb:1DKE|rcsb pdb:1DXT|rcsb pdb:1DXU|rcsb pdb:1DXV|rcsb pdb:1FN3|rcsb pdb:1G9V|rcsb pdb:1GBU|rcsb pdb:1GBV|rcsb pdb:1GLI|rcsb pdb:1GZX|rcsb pdb:1HAB|rcsb pdb:1HAC|rcsb pdb:1HBA|rcsb pdb:1HBB|rcsb pdb:1HBS|rcsb pdb:1HCO|rcsb pdb:1HDB|rcsb pdb:1HGA|rcsb pdb:1HGB|rcsb pdb:1HGC|rcsb pdb:1HHO|rcsb pdb:1IRD|rcsb pdb:1J3Y|rcsb pdb:1J40|rcsb pdb:1J41|rcsb pdb:1J7S|rcsb pdb:1J7W|rcsb pdb:1J7Y|rcsb pdb:1JY7|rcsb pdb:1J3Z|rcsb pdb:1K0Y|rcsb pdb:1K1K|rcsb pdb:1KD2|rcsb pdb:1LFL|rcsb pdb:1LFQ|rcsb pdb:1LFT|rcsb pdb:1LFV|rcsb pdb:1LFY|rcsb pdb:1LFZ|rcsb pdb:1LJW|rcsb pdb:1M9P|rcsb pdb:1MKO|rcsb pdb:1NEJ|rcsb pdb:1NIH|rcsb pdb:1NQP|rcsb pdb:1O1I|rcsb pdb:1O1J|rcsb pdb:1O1K|rcsb pdb:1O1L|rcsb pdb:1O1M|rcsb pdb:1O1N|rcsb pdb:1O1O|rcsb pdb:1O1P|rcsb pdb:1QI8|rcsb pdb:1QSH|rcsb pdb:1QSI|rcsb pdb:1QXD|rcsb pdb:1QXE|rcsb pdb:1R1X|rcsb pdb:1R1Y|rcsb pdb:1RPS|rcsb pdb:1RQ3|rcsb pdb:1RQ4|rcsb pdb:1RQA|rcsb pdb:1RVW|rcsb pdb:1SDK|rcsb pdb:1SDL|rcsb pdb:1THB|rcsb pdb:1UIW|rcsb pdb:1VWT|rcsb pdb:1XXT|rcsb pdb:1XY0|rcsb pdb:1XYE|reactome:R-HSA-1237044|reactome:R-HSA-1247673|reactome:R-HSA-2168880|reactome:R-HSA-6798695|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9707564|reactome:R-HSA-9707616|reactome:R-HSA-983231|rcsb pdb:7JY3|rcsb pdb:3WCP|rcsb pdb:3WHM|rcsb pdb:4FC3|rcsb pdb:4HHB|rcsb pdb:4IJ2|rcsb pdb:4L7Y|rcsb pdb:4M4A|rcsb pdb:4M4B|rcsb pdb:4MQC|rcsb pdb:4MQG|rcsb pdb:4MQH|rcsb pdb:4MQI|rcsb pdb:4N7N|rcsb pdb:4N7O|rcsb pdb:4N7P|rcsb pdb:4N8T|rcsb pdb:4NI0|rcsb pdb:3W4U|rcsb pdb:4NI1|rcsb pdb:4ROL|rcsb pdb:4WJG|rcsb pdb:4X0L|rcsb pdb:4XS0|rcsb pdb:5E29|rcsb pdb:5E6E|rcsb pdb:5E83|rcsb pdb:5EE4|rcsb pdb:5HU6|rcsb pdb:5HY8|rcsb pdb:5JDO|rcsb pdb:5KDQ|rcsb pdb:5KSI|rcsb pdb:5KSJ|rcsb pdb:5NI1|rcsb pdb:5SW7|rcsb pdb:5U3I|rcsb pdb:5UCU|rcsb pdb:5UFJ|rcsb pdb:5URC|rcsb pdb:5VMM|rcsb pdb:5WOG|rcsb pdb:5WOH|rcsb pdb:5X2R|rcsb pdb:5X2S|rcsb pdb:5X2T|rcsb pdb:5X2U|rcsb pdb:6BB5|rcsb pdb:6BNR|rcsb pdb:6BWP|rcsb pdb:6BWU|rcsb pdb:6DI4|rcsb pdb:6FQF|rcsb pdb:6HAL|rcsb pdb:4ROM|rcsb pdb:6HBW|rcsb pdb:6HK2|rcsb pdb:6KA9|rcsb pdb:6KAE|rcsb pdb:6KAH|rcsb pdb:6KAI|rcsb pdb:6KAO|rcsb pdb:6KAP|rcsb pdb:6KAQ|rcsb pdb:6KAR|rcsb pdb:6KAS|rcsb pdb:6KAT|rcsb pdb:6KAU|rcsb pdb:6KAV|rcsb pdb:6KYE|rcsb pdb:6L5V|rcsb pdb:6L5W|rcsb pdb:6L5X|rcsb pdb:6L5Y|rcsb pdb:6LCW|rcsb pdb:6LCX|rcsb pdb:6NBC|rcsb pdb:6NBD|rcsb pdb:6NQ5|rcsb pdb:6TB2|rcsb pdb:6XD9|rcsb pdb:6XDT|rcsb pdb:6XE7|rcsb pdb:7AET|rcsb pdb:7AEU|rcsb pdb:7AEV|rcsb pdb:7JJQ|rcsb pdb:7JXZ|rcsb pdb:7JY0|rcsb pdb:7JY1|dip:DIP-35526N - - comment:"author score: 30" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W/MFjTf3d4mRzCXRWgl0sk/mdX49606 rogid:Y5tl4dXE3PBfaK/0lROD6QJ4U+c9606 rigid:uXi79XFQL2FYImWOabR1VWj5GWk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23760 uniprotkb:Q9BSD7 intact:EBI-1167564|uniprotkb:Q16448|uniprotkb:Q53T90|uniprotkb:Q6GSJ9|uniprotkb:Q86UQ2|uniprotkb:Q86UQ3|uniprotkb:Q494Z3|uniprotkb:Q494Z4|uniprotkb:G5E9C1|ensembl:ENSP00000343052 intact:EBI-2689235|ensembl:ENSP00000355587 psi-mi:pax3_human(display_long)|uniprotkb:PAX3(gene name)|psi-mi:PAX3(display_short)|uniprotkb:HUP2(gene name synonym)|uniprotkb:HuP2(gene name synonym) psi-mi:ntpcr_human(display_long)|uniprotkb:Nucleoside triphosphate phosphohydrolase(gene name synonym)|uniprotkb:NTPCR(gene name)|psi-mi:NTPCR(display_short)|uniprotkb:C1orf57(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482229|imex:IM-26985-495 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000429.2|refseq:NP_039230.1|refseq:NP_852122.1|refseq:NP_001120838.1|refseq:NP_852123.1|refseq:NP_852124.1|refseq:NP_852125.1|refseq:NP_852126.1|ensembl:ENSG00000135903(gene)|ensembl:ENST00000350526(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR022106|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565|mint:P23760|rcsb pdb:3CMY|reactome:R-HSA-3214847 refseq:NP_115700.1|interpro:IPR027417|mint:Q9BSD7|rcsb pdb:2I3B|ensembl:ENSG00000135778(gene)|ensembl:ENST00000366628(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0016020"(membrane)|go:"GO:0017111"(nucleoside-triphosphatase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004948(Protein of unknown function DUF265)|refseq:NP_001316382.1 - - comment:"author score: 32" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W/MFjTf3d4mRzCXRWgl0sk/mdX49606 rogid:tJoP+XQzoa4urq6g1rdZhMWO49g9606 rigid:uXi79XFQL2FYImWOabR1VWj5GWk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23760 uniprotkb:P02452 intact:EBI-1167564|uniprotkb:Q16448|uniprotkb:Q53T90|uniprotkb:Q6GSJ9|uniprotkb:Q86UQ2|uniprotkb:Q86UQ3|uniprotkb:Q494Z3|uniprotkb:Q494Z4|uniprotkb:G5E9C1|ensembl:ENSP00000343052 intact:EBI-982999|uniprotkb:O76045|uniprotkb:P78441|uniprotkb:Q13896|uniprotkb:Q13902|uniprotkb:Q13903|uniprotkb:Q14037|uniprotkb:Q14992|uniprotkb:Q15176|uniprotkb:Q15201|uniprotkb:Q16050|uniprotkb:Q59F64|uniprotkb:Q7KZ30|uniprotkb:Q7KZ34|uniprotkb:Q8IVI5|ensembl:ENSP00000225964|uniprotkb:Q8N473|uniprotkb:Q9UML6|uniprotkb:Q9UMM7 psi-mi:pax3_human(display_long)|uniprotkb:PAX3(gene name)|psi-mi:PAX3(display_short)|uniprotkb:HUP2(gene name synonym)|uniprotkb:HuP2(gene name synonym) psi-mi:co1a1_human(display_long)|uniprotkb:Alpha-1 type I collagen(gene name synonym)|uniprotkb:COL1A1(gene name)|psi-mi:COL1A1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482229|imex:IM-26985-495 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000429.2|refseq:NP_039230.1|refseq:NP_852122.1|refseq:NP_001120838.1|refseq:NP_852123.1|refseq:NP_852124.1|refseq:NP_852125.1|refseq:NP_852126.1|ensembl:ENSG00000135903(gene)|ensembl:ENST00000350526(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR022106|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565|mint:P23760|rcsb pdb:3CMY|reactome:R-HSA-3214847 refseq:NP_000079.2|ensembl:ENSG00000108821(gene)|ensembl:ENST00000225964(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001503"(ossification)|go:"GO:0001568"(blood vessel development)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001957"(intramembranous ossification)|go:"GO:0001958"(endochondral ossification)|go:"GO:0002020"(protease binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005584"(collagen type I trimer)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007601"(visual perception)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0015031"(protein transport)|go:"GO:0030020"(extracellular matrix structural constituent conferring tensile strength)|go:"GO:0030141"(secretory granule)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031960"(response to corticosteroid)|go:"GO:0032355"(response to estradiol)|go:"GO:0032964"(collagen biosynthetic process)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034505"(tooth mineralization)|go:"GO:0038063"(collagen-activated tyrosine kinase receptor signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0043588"(skin development)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0044344"(cellular response to fibroblast growth factor stimulus)|go:"GO:0044691"(tooth eruption)|go:"GO:0046872"(metal ion binding)|go:"GO:0048407"(platelet-derived growth factor binding)|go:"GO:0048706"(embryonic skeletal system development)|go:"GO:0051591"(response to cAMP)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060325"(face morphogenesis)|go:"GO:0060346"(bone trabecula formation)|go:"GO:0060351"(cartilage development involved in endochondral bone morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071306"(cellular response to vitamin E)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:1902618"(cellular response to fluoride)|interpro:IPR000885(Fibrillar collagen, C-terminal)|interpro:IPR001007(von Willebrand factor, type C)|interpro:IPR008160(Collagen triple helix repeat)|mint:P02452|rcsb pdb:1Q7D|rcsb pdb:2LLP|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:5CTD|rcsb pdb:5CTI|rcsb pdb:5CVA|rcsb pdb:5CVB|rcsb pdb:5K31|rcsb pdb:5OU8|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|rcsb pdb:5OU9|rcsb pdb:7E7B|rcsb pdb:7E7D|reactome:R-HSA-114604|reactome:R-HSA-1442490|reactome:R-HSA-1474244|reactome:R-HSA-1650814|reactome:R-HSA-198933|reactome:R-HSA-2022090|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-2214320|reactome:R-HSA-2243919|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-3000480|reactome:R-HSA-430116|reactome:R-HSA-75892|reactome:R-HSA-76009|reactome:R-HSA-8874081|reactome:R-HSA-8940973|reactome:R-HSA-8948216|dip:DIP-36077N - - comment:"author score: 40" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W/MFjTf3d4mRzCXRWgl0sk/mdX49606 rogid:x83+B64Cl9zkAVeZ9RCo0BukkwU9606 rigid:uXi79XFQL2FYImWOabR1VWj5GWk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23760 uniprotkb:P0CG04 intact:EBI-1167564|uniprotkb:Q16448|uniprotkb:Q53T90|uniprotkb:Q6GSJ9|uniprotkb:Q86UQ2|uniprotkb:Q86UQ3|uniprotkb:Q494Z3|uniprotkb:Q494Z4|uniprotkb:G5E9C1|ensembl:ENSP00000343052 intact:EBI-1221063|uniprotkb:P80423|uniprotkb:A0M8Q4|uniprotkb:P01842|uniprotkb:A0A075B6K8 psi-mi:pax3_human(display_long)|uniprotkb:PAX3(gene name)|psi-mi:PAX3(display_short)|uniprotkb:HUP2(gene name synonym)|uniprotkb:HuP2(gene name synonym) psi-mi:iglc1_human(display_long)|uniprotkb:IGLC1(gene name)|psi-mi:IGLC1(display_short)|uniprotkb:Ig lambda chain C region MGC(gene name synonym)|uniprotkb:Ig lambda-1 chain C region(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482229|imex:IM-26985-495 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000429.2|refseq:NP_039230.1|refseq:NP_852122.1|refseq:NP_001120838.1|refseq:NP_852123.1|refseq:NP_852124.1|refseq:NP_852125.1|refseq:NP_852126.1|ensembl:ENSG00000135903(gene)|ensembl:ENST00000350526(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR022106|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565|mint:P23760|rcsb pdb:3CMY|reactome:R-HSA-3214847 interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|mint:P0CG04|interpro:IPR036179|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0034987"(immunoglobulin receptor binding)|go:"GO:0042571"(immunoglobulin complex, circulating)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|rcsb pdb:1ZVO|rcsb pdb:2FB4|rcsb pdb:2IG2|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|go:"GO:0045087"(innate immune response)|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664422|reactome:R-HSA-977606|reactome:R-HSA-983695|reactome:R-HSA-9664323 - - comment:"author score: 51" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W/MFjTf3d4mRzCXRWgl0sk/mdX49606 rogid:OOdxBXPI2Jzf9HxurFZjk3/L1DM9606 rigid:uXi79XFQL2FYImWOabR1VWj5GWk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23760 uniprotkb:Q12778 intact:EBI-1167564|uniprotkb:Q16448|uniprotkb:Q53T90|uniprotkb:Q6GSJ9|uniprotkb:Q86UQ2|uniprotkb:Q86UQ3|uniprotkb:Q494Z3|uniprotkb:Q494Z4|uniprotkb:G5E9C1|ensembl:ENSP00000343052 intact:EBI-1108782|uniprotkb:O43523|uniprotkb:Q5VYC7|uniprotkb:Q6NSK6|ensembl:ENSP00000368880 psi-mi:pax3_human(display_long)|uniprotkb:PAX3(gene name)|psi-mi:PAX3(display_short)|uniprotkb:HUP2(gene name synonym)|uniprotkb:HuP2(gene name synonym) psi-mi:foxo1_human(display_long)|uniprotkb:FOXO1(gene name)|psi-mi:FOXO1(display_short)|uniprotkb:FKHR(gene name synonym)|uniprotkb:FOXO1A(gene name synonym)|uniprotkb:Forkhead box protein O1A(gene name synonym)|uniprotkb:Forkhead in rhabdomyosarcoma(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482229|imex:IM-26985-495 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000429.2|refseq:NP_039230.1|refseq:NP_852122.1|refseq:NP_001120838.1|refseq:NP_852123.1|refseq:NP_852124.1|refseq:NP_852125.1|refseq:NP_852126.1|ensembl:ENSG00000135903(gene)|ensembl:ENST00000350526(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0007517"(muscle organ development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048856"(anatomical structure development)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001523(Paired box protein, N-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR022106|interpro:IPR036388|interpro:IPR043182|interpro:IPR043565|mint:P23760|rcsb pdb:3CMY|reactome:R-HSA-3214847 ensembl:ENSG00000150907(gene)|ensembl:ENST00000379561(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006473"(protein acetylation)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0070166"(enamel mineralization)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070417"(cellular response to cold)|go:"GO:0070542"(response to fatty acid)|go:"GO:0071455"(cellular response to hyperoxia)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0097009"(energy homeostasis)|go:"GO:1902617"(response to fluoride)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|interpro:IPR001766(Fork head transcription factor)|interpro:IPR030456|interpro:IPR032067|interpro:IPR032068|interpro:IPR036388|interpro:IPR036390|mint:Q12778|rcsb pdb:3CO6|rcsb pdb:3CO7|rcsb pdb:3COA|rcsb pdb:4LG0|rcsb pdb:5DUI|rcsb pdb:6LBI|rcsb pdb:6QVW|rcsb pdb:6QZR|rcsb pdb:6QZS|reactome:R-HSA-198693|reactome:R-HSA-210745|reactome:R-HSA-211163|reactome:R-HSA-5674400|reactome:R-HSA-5687128|reactome:R-HSA-6785807|reactome:R-HSA-9614399|reactome:R-HSA-9614657|reactome:R-HSA-9615017|reactome:R-HSA-9617629|reactome:R-HSA-9617828|refseq:NP_002006.2|dip:DIP-35654N - - comment:"author score: 147" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W/MFjTf3d4mRzCXRWgl0sk/mdX49606 rogid:oc4WR5KxeJntPcwhZU8zHFyTHCQ9606 rigid:uXi79XFQL2FYImWOabR1VWj5GWk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43189 uniprotkb:Q16576 intact:EBI-530034|uniprotkb:B1AZX2|uniprotkb:B1AZX3|uniprotkb:O60929|uniprotkb:Q96KM7|uniprotkb:Q5SU07|uniprotkb:Q5SU08|ensembl:ENSP00000363640|ensembl:ENSP00000391901|ensembl:ENSP00000407295 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 psi-mi:phf1_human(display_long)|uniprotkb:PCL1(gene name synonym)|uniprotkb:Polycomb-like protein 1(gene name synonym)|uniprotkb:PHF1(gene name)|psi-mi:PHF1(display_short) psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482259|imex:IM-26985-119 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011512964.1|refseq:NP_002627.1|refseq:NP_077084.1|ensembl:ENSG00000112511(gene)|ensembl:ENSG00000225553(gene)|ensembl:ENST00000374516(transcript)|ensembl:ENST00000427869(transcript)|ensembl:ENST00000454914(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR031202|interpro:IPR040477|mint:O43189|rcsb pdb:2E5P|rcsb pdb:2M0O|rcsb pdb:4HCZ|rcsb pdb:5XFN|rcsb pdb:5XFO|rcsb pdb:5XFP|rcsb pdb:6WAT|rcsb pdb:6WAV|reactome:R-HSA-212300|dip:DIP-34001N refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N - - comment:"author score: 30" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8n8g2LqzuOQb8cFC7tE1j/xBvkI9606 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rigid:eyaJxd/r+7+B9jesAbeOR5peeMo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43189 uniprotkb:Q96JN0 intact:EBI-530034|uniprotkb:B1AZX2|uniprotkb:B1AZX3|uniprotkb:O60929|uniprotkb:Q96KM7|uniprotkb:Q5SU07|uniprotkb:Q5SU08|ensembl:ENSP00000363640|ensembl:ENSP00000391901|ensembl:ENSP00000407295 intact:EBI-746045|uniprotkb:Q9H945|uniprotkb:Q9Y457|ensembl:ENSP00000348298|ensembl:ENSP00000360138|ensembl:ENSP00000360144|ensembl:ENSP00000501560|ensembl:ENSP00000501639|ensembl:ENSP00000502633|intact:EBI-8833163|uniprotkb:D3DR47|uniprotkb:Q5VW16|uniprotkb:Q7Z723|uniprotkb:Q86T32|uniprotkb:Q86T33|uniprotkb:Q8N3L6|uniprotkb:Q8N655 psi-mi:phf1_human(display_long)|uniprotkb:PCL1(gene name synonym)|uniprotkb:Polycomb-like protein 1(gene name synonym)|uniprotkb:PHF1(gene name)|psi-mi:PHF1(display_short) psi-mi:lcor_human(display_long)|uniprotkb:LCOR(gene name)|psi-mi:LCOR(display_short)|uniprotkb:C10orf12(gene name synonym)|uniprotkb:KIAA1795(gene name synonym)|uniprotkb:MLR2(gene name synonym)|uniprotkb:Mblk1-related protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482259|imex:IM-26985-119 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011512964.1|refseq:NP_002627.1|refseq:NP_077084.1|ensembl:ENSG00000112511(gene)|ensembl:ENSG00000225553(gene)|ensembl:ENST00000374516(transcript)|ensembl:ENST00000427869(transcript)|ensembl:ENST00000454914(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR031202|interpro:IPR040477|mint:O43189|rcsb pdb:2E5P|rcsb pdb:2M0O|rcsb pdb:4HCZ|rcsb pdb:5XFN|rcsb pdb:5XFO|rcsb pdb:5XFP|rcsb pdb:6WAT|rcsb pdb:6WAV|reactome:R-HSA-212300|dip:DIP-34001N ensembl:ENSG00000196233(gene)|ensembl:ENST00000356016(transcript)|ensembl:ENST00000371097(transcript)|ensembl:ENST00000371103(transcript)|ensembl:ENST00000675471(transcript)|ensembl:ENST00000675537(transcript)|ensembl:ENST00000675971(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|mint:Q96JN0|rcsb pdb:2COB|refseq:NP_001164236.1|refseq:NP_001164237.1|refseq:NP_115816.2|refseq:XP_016872275.1|refseq:XP_016872276.1|refseq:XP_016872277.1|refseq:NP_001333445.1 - - comment:"author score: 43" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8n8g2LqzuOQb8cFC7tE1j/xBvkI9606 rogid:cOnk6EDDff86yaG1uG+dxEQ1Z689606 rigid:eyaJxd/r+7+B9jesAbeOR5peeMo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43189 uniprotkb:Q09028 intact:EBI-530034|uniprotkb:B1AZX2|uniprotkb:B1AZX3|uniprotkb:O60929|uniprotkb:Q96KM7|uniprotkb:Q5SU07|uniprotkb:Q5SU08|ensembl:ENSP00000363640|ensembl:ENSP00000391901|ensembl:ENSP00000407295 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 psi-mi:phf1_human(display_long)|uniprotkb:PCL1(gene name synonym)|uniprotkb:Polycomb-like protein 1(gene name synonym)|uniprotkb:PHF1(gene name)|psi-mi:PHF1(display_short) psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482259|imex:IM-26985-119 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011512964.1|refseq:NP_002627.1|refseq:NP_077084.1|ensembl:ENSG00000112511(gene)|ensembl:ENSG00000225553(gene)|ensembl:ENST00000374516(transcript)|ensembl:ENST00000427869(transcript)|ensembl:ENST00000454914(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR031202|interpro:IPR040477|mint:O43189|rcsb pdb:2E5P|rcsb pdb:2M0O|rcsb pdb:4HCZ|rcsb pdb:5XFN|rcsb pdb:5XFO|rcsb pdb:5XFP|rcsb pdb:6WAT|rcsb pdb:6WAV|reactome:R-HSA-212300|dip:DIP-34001N ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N - - comment:"author score: 58" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8n8g2LqzuOQb8cFC7tE1j/xBvkI9606 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rigid:eyaJxd/r+7+B9jesAbeOR5peeMo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43189 uniprotkb:Q92800 intact:EBI-530034|uniprotkb:B1AZX2|uniprotkb:B1AZX3|uniprotkb:O60929|uniprotkb:Q96KM7|uniprotkb:Q5SU07|uniprotkb:Q5SU08|ensembl:ENSP00000363640|ensembl:ENSP00000391901|ensembl:ENSP00000407295 intact:EBI-8830732|uniprotkb:B4E3R7|uniprotkb:O43287|uniprotkb:A6NCH6|uniprotkb:Q14459|uniprotkb:Q53XP3|uniprotkb:B4DSS2|uniprotkb:B4DIJ1|uniprotkb:B4DIZ7|ensembl:ENSP00000404658|ensembl:ENSP00000466924 psi-mi:phf1_human(display_long)|uniprotkb:PCL1(gene name synonym)|uniprotkb:Polycomb-like protein 1(gene name synonym)|uniprotkb:PHF1(gene name)|psi-mi:PHF1(display_short) psi-mi:ezh1_human(display_long)|uniprotkb:ENX-2(gene name synonym)|uniprotkb:Enhancer of zeste homolog 1(gene name synonym)|uniprotkb:KIAA0388(gene name synonym)|uniprotkb:EZH1(gene name)|psi-mi:EZH1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482259|imex:IM-26985-119 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011512964.1|refseq:NP_002627.1|refseq:NP_077084.1|ensembl:ENSG00000112511(gene)|ensembl:ENSG00000225553(gene)|ensembl:ENST00000374516(transcript)|ensembl:ENST00000427869(transcript)|ensembl:ENST00000454914(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR031202|interpro:IPR040477|mint:O43189|rcsb pdb:2E5P|rcsb pdb:2M0O|rcsb pdb:4HCZ|rcsb pdb:5XFN|rcsb pdb:5XFO|rcsb pdb:5XFP|rcsb pdb:6WAT|rcsb pdb:6WAV|reactome:R-HSA-212300|dip:DIP-34001N refseq:NP_001308008.1|refseq:NP_001308010.1|refseq:NP_001308011.1|refseq:NP_001982.2|dip:DIP-58580N|ensembl:ENSG00000108799(gene)|ensembl:ENST00000428826(transcript)|ensembl:ENST00000592743(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0021766"(hippocampus development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0031507"(heterochromatin assembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR021654|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR032926|interpro:IPR041343|interpro:IPR041355|interpro:IPR044438|mint:Q92800|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP - - comment:"author score: 61" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8n8g2LqzuOQb8cFC7tE1j/xBvkI9606 rogid:qp3eqBCgiaoA6VSSyqpW1d9YKN49606 rigid:eyaJxd/r+7+B9jesAbeOR5peeMo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43189 uniprotkb:Q15022 intact:EBI-530034|uniprotkb:B1AZX2|uniprotkb:B1AZX3|uniprotkb:O60929|uniprotkb:Q96KM7|uniprotkb:Q5SU07|uniprotkb:Q5SU08|ensembl:ENSP00000363640|ensembl:ENSP00000391901|ensembl:ENSP00000407295 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 psi-mi:phf1_human(display_long)|uniprotkb:PCL1(gene name synonym)|uniprotkb:Polycomb-like protein 1(gene name synonym)|uniprotkb:PHF1(gene name)|psi-mi:PHF1(display_short) psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482259|imex:IM-26985-119 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011512964.1|refseq:NP_002627.1|refseq:NP_077084.1|ensembl:ENSG00000112511(gene)|ensembl:ENSG00000225553(gene)|ensembl:ENST00000374516(transcript)|ensembl:ENST00000427869(transcript)|ensembl:ENST00000454914(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR031202|interpro:IPR040477|mint:O43189|rcsb pdb:2E5P|rcsb pdb:2M0O|rcsb pdb:4HCZ|rcsb pdb:5XFN|rcsb pdb:5XFO|rcsb pdb:5XFP|rcsb pdb:6WAT|rcsb pdb:6WAV|reactome:R-HSA-212300|dip:DIP-34001N dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421 - - comment:"author score: 132" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8n8g2LqzuOQb8cFC7tE1j/xBvkI9606 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 rigid:eyaJxd/r+7+B9jesAbeOR5peeMo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43189 uniprotkb:Q15910 intact:EBI-530034|uniprotkb:B1AZX2|uniprotkb:B1AZX3|uniprotkb:O60929|uniprotkb:Q96KM7|uniprotkb:Q5SU07|uniprotkb:Q5SU08|ensembl:ENSP00000363640|ensembl:ENSP00000391901|ensembl:ENSP00000407295 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 psi-mi:phf1_human(display_long)|uniprotkb:PCL1(gene name synonym)|uniprotkb:Polycomb-like protein 1(gene name synonym)|uniprotkb:PHF1(gene name)|psi-mi:PHF1(display_short) psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482259|imex:IM-26985-119 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011512964.1|refseq:NP_002627.1|refseq:NP_077084.1|ensembl:ENSG00000112511(gene)|ensembl:ENSG00000225553(gene)|ensembl:ENST00000374516(transcript)|ensembl:ENST00000427869(transcript)|ensembl:ENST00000454914(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR031202|interpro:IPR040477|mint:O43189|rcsb pdb:2E5P|rcsb pdb:2M0O|rcsb pdb:4HCZ|rcsb pdb:5XFN|rcsb pdb:5XFO|rcsb pdb:5XFP|rcsb pdb:6WAT|rcsb pdb:6WAV|reactome:R-HSA-212300|dip:DIP-34001N refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N - - comment:"author score: 138" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8n8g2LqzuOQb8cFC7tE1j/xBvkI9606 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 rigid:eyaJxd/r+7+B9jesAbeOR5peeMo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43189 uniprotkb:O75530 intact:EBI-530034|uniprotkb:B1AZX2|uniprotkb:B1AZX3|uniprotkb:O60929|uniprotkb:Q96KM7|uniprotkb:Q5SU07|uniprotkb:Q5SU08|ensembl:ENSP00000363640|ensembl:ENSP00000391901|ensembl:ENSP00000407295 intact:EBI-923794|intact:EBI-2839778|intact:EBI-1177693|uniprotkb:A8K7V5|uniprotkb:Q6NTH2|uniprotkb:Q7LDA5|uniprotkb:Q7LDG8|uniprotkb:Q86VV2|uniprotkb:Q9UNY7|uniprotkb:O00149|ensembl:ENSP00000263360|ensembl:ENSP00000500834 psi-mi:phf1_human(display_long)|uniprotkb:PCL1(gene name synonym)|uniprotkb:Polycomb-like protein 1(gene name synonym)|uniprotkb:PHF1(gene name)|psi-mi:PHF1(display_short) psi-mi:eed_human(display_long)|uniprotkb:EED(gene name)|psi-mi:EED(display_short)|uniprotkb:WD protein associating with integrin cytoplasmic tails 1(gene name synonym)|uniprotkb:Embryonic ectoderm development protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482259|imex:IM-26985-119 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011512964.1|refseq:NP_002627.1|refseq:NP_077084.1|ensembl:ENSG00000112511(gene)|ensembl:ENSG00000225553(gene)|ensembl:ENST00000374516(transcript)|ensembl:ENST00000427869(transcript)|ensembl:ENST00000454914(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0061087"(positive regulation of histone H3-K27 methylation)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR025894|interpro:IPR031202|interpro:IPR040477|mint:O43189|rcsb pdb:2E5P|rcsb pdb:2M0O|rcsb pdb:4HCZ|rcsb pdb:5XFN|rcsb pdb:5XFO|rcsb pdb:5XFP|rcsb pdb:6WAT|rcsb pdb:6WAV|reactome:R-HSA-212300|dip:DIP-34001N refseq:NP_003788.2|refseq:NP_001294936.1|dip:DIP-36673N|ensembl:ENSG00000074266(gene)|ensembl:ENST00000263360(transcript)|ensembl:ENST00000672825(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0021510"(spinal cord development)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:O75530|rcsb pdb:3IIW|rcsb pdb:3IIY|rcsb pdb:3IJ0|rcsb pdb:3IJ1|rcsb pdb:3IJC|rcsb pdb:3JPX|rcsb pdb:3JZG|rcsb pdb:3JZH|rcsb pdb:3JZN|rcsb pdb:3K26|rcsb pdb:3K27|rcsb pdb:4W2R|rcsb pdb:4X3E|rcsb pdb:5GSA|rcsb pdb:5H13|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5K0M|rcsb pdb:5LS6|rcsb pdb:5TTW|rcsb pdb:5U5H|rcsb pdb:5U5K|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5U69|rcsb pdb:5U6D|rcsb pdb:5U8A|rcsb pdb:5U8F|rcsb pdb:5WG6|rcsb pdb:5WP3|rcsb pdb:5WUK|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6SFB|rcsb pdb:6SFC|rcsb pdb:6U4Y|rcsb pdb:6V3X|rcsb pdb:6V3Y|rcsb pdb:6W7F|rcsb pdb:6W7G|rcsb pdb:6WKR|rcsb pdb:6YVI|rcsb pdb:6YVJ|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7KXT|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421 - - comment:"author score: 142" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8n8g2LqzuOQb8cFC7tE1j/xBvkI9606 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA9606 rigid:eyaJxd/r+7+B9jesAbeOR5peeMo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86WI1 uniprotkb:P24928 intact:EBI-16247978|ensembl:ENSP00000367655|uniprotkb:Q567P2|uniprotkb:Q9UF27 intact:EBI-295301|uniprotkb:A6NN93|uniprotkb:B9EH88|uniprotkb:Q6NX41|intact:EBI-17957133|intact:EBI-14758660|intact:EBI-13324911|intact:EBI-23311874 psi-mi:pkhl1_human(display_long)|uniprotkb:PKHD1L1(gene name)|psi-mi:PKHD1L1(display_short)|uniprotkb:Polycystic kidney and hepatic disease 1-like protein 1(gene name synonym) psi-mi:rpb1_human(display_long)|uniprotkb:POLR2A(gene name)|psi-mi:POLR2A(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit A(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:POLR2(gene name synonym)|uniprotkb:RNA-directed RNA polymerase II subunit RPB1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25482622|imex:IM-26985-499 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000205038(gene)|ensembl:ENST00000378402(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006955"(immune response)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032426"(stereocilium tip)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0120234"(stereocilium coat)|interpro:IPR002909(Cell surface receptor IPT/TIG)|interpro:IPR006626(Parallel beta-helix repeat)|interpro:IPR008972(Cupredoxin)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR011658(PA14)|interpro:IPR012334(Pectin lyase fold)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR019316|interpro:IPR029927|interpro:IPR037524|mint:Q86WI1|refseq:NP_803875.2|dip:DIP-59023N refseq:NP_000928.1|mint:P24928|dip:DIP-29011N|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0019900"(kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:2GHQ|rcsb pdb:2GHT|rcsb pdb:2LTO|rcsb pdb:3D9K|rcsb pdb:3D9L|rcsb pdb:3D9M|rcsb pdb:3D9N|rcsb pdb:3D9O|rcsb pdb:3D9P|rcsb pdb:4JXT|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:5M3H|rcsb pdb:5M3J|rcsb pdb:6DRD|rcsb pdb:6F5P|rcsb pdb:6G0R|rcsb pdb:6IC8|rcsb pdb:6IC9|rcsb pdb:6O9L|rcsb pdb:6Q5Y|rcsb pdb:6XKB|rcsb pdb:6XRE|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095 - comment:"author score: 12" - figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:tObc1NvU3eHNgVwd5V5onbUAFMU9606 rogid:Si2fgh4AMaNtlzvSQhvsuPusX7s9606 rigid:kpJDzLQC/1SUioVYXq5dP7Jbymc false - tandem tag:n-n - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00444 uniprotkb:Q9Y2H1 intact:EBI-746202|uniprotkb:Q8IYF0|uniprotkb:Q96Q95|uniprotkb:B2RAL0|uniprotkb:B7Z837|uniprotkb:B7Z8G7|uniprotkb:Q9UD84|uniprotkb:Q9UDE2|ensembl:ENSP00000270861 intact:EBI-991501|uniprotkb:Q8TBX7|uniprotkb:A8K4U0|uniprotkb:B4E3J8|ensembl:ENSP00000373684 psi-mi:plk4_human(display_long)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym)|uniprotkb:PLK4(gene name)|psi-mi:PLK4(display_short)|uniprotkb:SAK(gene name synonym)|uniprotkb:STK18(gene name synonym) psi-mi:st38l_human(display_long)|uniprotkb:NDR2 protein kinase(gene name synonym)|uniprotkb:Nuclear Dbf2-related kinase 2(gene name synonym)|uniprotkb:STK38L(gene name)|psi-mi:STK38L(display_short)|uniprotkb:KIAA0965(gene name synonym)|uniprotkb:NDR2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482559|imex:IM-26985-197 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177728.1|refseq:NP_001177730.1|refseq:NP_055079.3|dip:DIP-34467N|rcsb pdb:5LHZ|rcsb pdb:6N45|rcsb pdb:6N46|rcsb pdb:6W38|rcsb pdb:6W3I|rcsb pdb:6W3J|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|rcsb pdb:5LHY|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000142731(gene)|ensembl:ENST00000270861(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:O00444|rcsb pdb:2N19|rcsb pdb:3COK|rcsb pdb:4JXF|rcsb pdb:4N7V|rcsb pdb:4N7Z|rcsb pdb:4N9J|rcsb pdb:4YUR|rcsb pdb:4YYP refseq:XP_006719121.1|ensembl:ENSG00000211455(gene)|ensembl:ENST00000389032(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003779"(actin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0051128"(regulation of cellular component organization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0005524"(ATP binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|mint:Q9Y2H1|rcsb pdb:5XQZ|refseq:NP_055815.1|refseq:XP_011518915.1|refseq:XP_016874525.1 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xqjVEnoGXDk/+2AzLRAkyPK80OI9606 rogid:lKXWdkeLMD/YCxa1oQz9k0aoW3I9606 rigid:lbKLlozX9PaMOzH1CB/kW5Zt8no false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00444 uniprotkb:Q9UPU3 intact:EBI-746202|uniprotkb:Q8IYF0|uniprotkb:Q96Q95|uniprotkb:B2RAL0|uniprotkb:B7Z837|uniprotkb:B7Z8G7|uniprotkb:Q9UD84|uniprotkb:Q9UDE2|ensembl:ENSP00000270861 intact:EBI-7484437|uniprotkb:Q9NQJ2|intact:MINT-1326895|uniprotkb:Q5VXF9|ensembl:ENSP00000358715 psi-mi:plk4_human(display_long)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym)|uniprotkb:PLK4(gene name)|psi-mi:PLK4(display_short)|uniprotkb:SAK(gene name synonym)|uniprotkb:STK18(gene name synonym) psi-mi:sorc3_human(display_long)|uniprotkb:SORCS3(gene name)|psi-mi:SORCS3(display_short)|uniprotkb:KIAA1059(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482559|imex:IM-26985-197 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177728.1|refseq:NP_001177730.1|refseq:NP_055079.3|dip:DIP-34467N|rcsb pdb:5LHZ|rcsb pdb:6N45|rcsb pdb:6N46|rcsb pdb:6W38|rcsb pdb:6W3I|rcsb pdb:6W3J|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|rcsb pdb:5LHY|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000142731(gene)|ensembl:ENST00000270861(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:O00444|rcsb pdb:2N19|rcsb pdb:3COK|rcsb pdb:4JXF|rcsb pdb:4N7V|rcsb pdb:4N7Z|rcsb pdb:4N9J|rcsb pdb:4YUR|rcsb pdb:4YYP refseq:NP_055793.1|ensembl:ENSG00000156395(gene)|ensembl:ENST00000369701(transcript)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0008188"(neuropeptide receptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|go:"GO:1900452"(regulation of long-term synaptic depression)|interpro:IPR000601(PKD)|interpro:IPR006581(VPS10)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031777|interpro:IPR031778|interpro:IPR035986|mint:Q9UPU3 - - comment:mint|comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xqjVEnoGXDk/+2AzLRAkyPK80OI9606 rogid:lT3HTfWJN1KbRETpE8RIBNCRtYM9606 rigid:lbKLlozX9PaMOzH1CB/kW5Zt8no false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00444 uniprotkb:Q15393 intact:EBI-746202|uniprotkb:Q8IYF0|uniprotkb:Q96Q95|uniprotkb:B2RAL0|uniprotkb:B7Z837|uniprotkb:B7Z8G7|uniprotkb:Q9UD84|uniprotkb:Q9UDE2|ensembl:ENSP00000270861 intact:EBI-346977|uniprotkb:Q6NTI8|uniprotkb:Q96GC0|uniprotkb:Q9BPY2|uniprotkb:Q9UFX7|uniprotkb:Q9UJ29|ensembl:ENSP00000305790 psi-mi:plk4_human(display_long)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym)|uniprotkb:PLK4(gene name)|psi-mi:PLK4(display_short)|uniprotkb:SAK(gene name synonym)|uniprotkb:STK18(gene name synonym) psi-mi:sf3b3_human(display_long)|uniprotkb:SF3B3(gene name)|psi-mi:SF3B3(display_short)|uniprotkb:KIAA0017(gene name synonym)|uniprotkb:SAP130(gene name synonym)|uniprotkb:Spliceosome-associated protein 130(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 130 kDa subunit(gene name synonym)|uniprotkb:STAF130(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482559|imex:IM-26985-197 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177728.1|refseq:NP_001177730.1|refseq:NP_055079.3|dip:DIP-34467N|rcsb pdb:5LHZ|rcsb pdb:6N45|rcsb pdb:6N46|rcsb pdb:6W38|rcsb pdb:6W3I|rcsb pdb:6W3J|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|rcsb pdb:5LHY|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000142731(gene)|ensembl:ENST00000270861(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:O00444|rcsb pdb:2N19|rcsb pdb:3COK|rcsb pdb:4JXF|rcsb pdb:4N7V|rcsb pdb:4N7Z|rcsb pdb:4N9J|rcsb pdb:4YUR|rcsb pdb:4YYP refseq:NP_036558.3|dip:DIP-28152N|ensembl:ENSG00000189091(gene)|ensembl:ENST00000302516(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|rcsb pdb:5O9Z|go:"GO:0005654"(nucleoplasm)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|go:"GO:0005730"(nucleolus)|go:"GO:0008380"(RNA splicing)|rcsb pdb:5ZYA|rcsb pdb:6AH0|go:"GO:0030620"(U2 snRNA binding)|rcsb pdb:6AHD|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR004871(Cleavage and polyadenylation specificity factor, A subunit, C-terminal)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR018846|interpro:IPR036322|mint:Q15393|rcsb pdb:5IFE - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xqjVEnoGXDk/+2AzLRAkyPK80OI9606 rogid:gnCSXjZ/bwNXair6kyQUKoKIwbM9606 rigid:lbKLlozX9PaMOzH1CB/kW5Zt8no false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00444 uniprotkb:Q9Y657 intact:EBI-746202|uniprotkb:Q8IYF0|uniprotkb:Q96Q95|uniprotkb:B2RAL0|uniprotkb:B7Z837|uniprotkb:B7Z8G7|uniprotkb:Q9UD84|uniprotkb:Q9UDE2|ensembl:ENSP00000270861 intact:EBI-727129|uniprotkb:Q7KZJ8|uniprotkb:Q9GZT2|uniprotkb:Q9H0N7|uniprotkb:A8K0X6|uniprotkb:B3KRQ4|ensembl:ENSP00000365019 psi-mi:plk4_human(display_long)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym)|uniprotkb:PLK4(gene name)|psi-mi:PLK4(display_short)|uniprotkb:SAK(gene name synonym)|uniprotkb:STK18(gene name synonym) psi-mi:spin1_human(display_long)|uniprotkb:Ovarian cancer-related protein(gene name synonym)|uniprotkb:SPIN1(gene name)|psi-mi:SPIN1(display_short)|uniprotkb:OCR(gene name synonym)|uniprotkb:SPIN(gene name synonym)|uniprotkb:Spindlin1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482559|imex:IM-26985-197 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177728.1|refseq:NP_001177730.1|refseq:NP_055079.3|dip:DIP-34467N|rcsb pdb:5LHZ|rcsb pdb:6N45|rcsb pdb:6N46|rcsb pdb:6W38|rcsb pdb:6W3I|rcsb pdb:6W3J|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|rcsb pdb:5LHY|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000142731(gene)|ensembl:ENST00000270861(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:O00444|rcsb pdb:2N19|rcsb pdb:3COK|rcsb pdb:4JXF|rcsb pdb:4N7V|rcsb pdb:4N7Z|rcsb pdb:4N9J|rcsb pdb:4YUR|rcsb pdb:4YYP refseq:NP_006708.2|ensembl:ENSG00000106723(gene)|ensembl:ENST00000375859(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007276"(gamete generation)|go:"GO:0009303"(rRNA transcription)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR003671(Spindlin/spermiogenesis-specific protein)|interpro:IPR029565|interpro:IPR042567|mint:Q9Y657|rcsb pdb:2NS2|rcsb pdb:4H75|rcsb pdb:4MZF|rcsb pdb:4MZG|rcsb pdb:4MZH|rcsb pdb:5JSG|rcsb pdb:5JSJ|rcsb pdb:5Y5W|rcsb pdb:6I8B|rcsb pdb:6I8L|rcsb pdb:6I8Y|rcsb pdb:6QPL|rcsb pdb:7BQZ|rcsb pdb:7BU9|rcsb pdb:7CNA|dip:DIP-40062N - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xqjVEnoGXDk/+2AzLRAkyPK80OI9606 rogid:OY/wCdms/yjDXj5aY2QffHXXXUY9606 rigid:lbKLlozX9PaMOzH1CB/kW5Zt8no false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00444 uniprotkb:P23588 intact:EBI-746202|uniprotkb:Q8IYF0|uniprotkb:Q96Q95|uniprotkb:B2RAL0|uniprotkb:B7Z837|uniprotkb:B7Z8G7|uniprotkb:Q9UD84|uniprotkb:Q9UDE2|ensembl:ENSP00000270861 intact:EBI-970310|ensembl:ENSP00000262056|uniprotkb:Q4G0E3|uniprotkb:Q53HQ2|uniprotkb:Q6GPH5|uniprotkb:Q6IB46|uniprotkb:Q8WYK5|uniprotkb:B4DS13 psi-mi:plk4_human(display_long)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym)|uniprotkb:PLK4(gene name)|psi-mi:PLK4(display_short)|uniprotkb:SAK(gene name synonym)|uniprotkb:STK18(gene name synonym) psi-mi:if4b_human(display_long)|uniprotkb:EIF4B(gene name)|psi-mi:EIF4B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482559|imex:IM-26985-197 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177728.1|refseq:NP_001177730.1|refseq:NP_055079.3|dip:DIP-34467N|rcsb pdb:5LHZ|rcsb pdb:6N45|rcsb pdb:6N46|rcsb pdb:6W38|rcsb pdb:6W3I|rcsb pdb:6W3J|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|rcsb pdb:5LHY|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000142731(gene)|ensembl:ENST00000270861(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:O00444|rcsb pdb:2N19|rcsb pdb:3COK|rcsb pdb:4JXF|rcsb pdb:4N7V|rcsb pdb:4N7Z|rcsb pdb:4N9J|rcsb pdb:4YUR|rcsb pdb:4YYP ensembl:ENSG00000063046(gene)|ensembl:ENST00000262056(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0030425"(dendrite)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034057"(RNA strand-exchange activity)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0097010"(eukaryotic translation initiation factor 4F complex assembly)|go:"GO:0098794"(postsynapse)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033107|interpro:IPR035979|mint:P23588|rcsb pdb:1WI8|rcsb pdb:2J76|rcsb pdb:6FEC|reactome:R-HSA-156827|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_001408.2|refseq:NP_001317583.1 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xqjVEnoGXDk/+2AzLRAkyPK80OI9606 rogid:6QlRkSj6suC5apkUxdZhOq+OMBc9606 rigid:lbKLlozX9PaMOzH1CB/kW5Zt8no false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00444 uniprotkb:Q9GZS3 intact:EBI-746202|uniprotkb:Q8IYF0|uniprotkb:Q96Q95|uniprotkb:B2RAL0|uniprotkb:B7Z837|uniprotkb:B7Z8G7|uniprotkb:Q9UD84|uniprotkb:Q9UDE2|ensembl:ENSP00000270861 intact:EBI-358545|uniprotkb:D3DW84|uniprotkb:Q6IA22|uniprotkb:Q7Z4X4|ensembl:ENSP00000267973|ensembl:ENSP00000453801 psi-mi:plk4_human(display_long)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym)|uniprotkb:PLK4(gene name)|psi-mi:PLK4(display_short)|uniprotkb:SAK(gene name synonym)|uniprotkb:STK18(gene name synonym) psi-mi:wdr61_human(display_long)|uniprotkb:WDR61(gene name)|psi-mi:WDR61(display_short)|uniprotkb:Meiotic recombination REC14 protein homolog(gene name synonym)|uniprotkb:SKI8 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482559|imex:IM-26985-197 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177728.1|refseq:NP_001177730.1|refseq:NP_055079.3|dip:DIP-34467N|rcsb pdb:5LHZ|rcsb pdb:6N45|rcsb pdb:6N46|rcsb pdb:6W38|rcsb pdb:6W3I|rcsb pdb:6W3J|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|rcsb pdb:5LHY|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000142731(gene)|ensembl:ENST00000270861(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:O00444|rcsb pdb:2N19|rcsb pdb:3COK|rcsb pdb:4JXF|rcsb pdb:4N7V|rcsb pdb:4N7Z|rcsb pdb:4N9J|rcsb pdb:4YUR|rcsb pdb:4YYP refseq:NP_079510.1|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9GZS3|rcsb pdb:3OW8|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-429958|reactome:R-HSA-674695|reactome:R-HSA-75955|ensembl:ENSG00000140395(gene)|ensembl:ENST00000267973(transcript)|ensembl:ENST00000558311(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0055087"(Ski complex)|reactome:R-HSA-8866654|refseq:XP_011520396.1|refseq:NP_001290176.1|refseq:NP_001290177.1|dip:DIP-36672N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xqjVEnoGXDk/+2AzLRAkyPK80OI9606 rogid:yVcjv2BXXr3VFSR7OcJ/1u9L6gw9606 rigid:lbKLlozX9PaMOzH1CB/kW5Zt8no false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00444 uniprotkb:P98175 intact:EBI-746202|uniprotkb:Q8IYF0|uniprotkb:Q96Q95|uniprotkb:B2RAL0|uniprotkb:B7Z837|uniprotkb:B7Z8G7|uniprotkb:Q9UD84|uniprotkb:Q9UDE2|ensembl:ENSP00000270861 intact:EBI-721525|uniprotkb:Q14136|uniprotkb:C4AM81|uniprotkb:Q9BTE4|intact:EBI-1642096|intact:EBI-739959|uniprotkb:Q5JRR2|uniprotkb:Q9BTX0|uniprotkb:Q9NTB1|uniprotkb:A0A0A0MR66|ensembl:ENSP00000366829 psi-mi:plk4_human(display_long)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym)|uniprotkb:PLK4(gene name)|psi-mi:PLK4(display_short)|uniprotkb:SAK(gene name synonym)|uniprotkb:STK18(gene name synonym) psi-mi:rbm10_human(display_long)|uniprotkb:RNA-binding motif protein 10(gene name synonym)|uniprotkb:G patch domain-containing protein 9(gene name synonym)|uniprotkb:RBM10(gene name)|psi-mi:RBM10(display_short)|uniprotkb:KIAA0122(gene name synonym)|uniprotkb:DXS8237E(gene name synonym)|uniprotkb:GPATC9(gene name synonym)|uniprotkb:GPATCH9(gene name synonym)|uniprotkb:RNA-binding protein S1-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482559|imex:IM-26985-197 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177728.1|refseq:NP_001177730.1|refseq:NP_055079.3|dip:DIP-34467N|rcsb pdb:5LHZ|rcsb pdb:6N45|rcsb pdb:6N46|rcsb pdb:6W38|rcsb pdb:6W3I|rcsb pdb:6W3J|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|rcsb pdb:5LHY|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000142731(gene)|ensembl:ENST00000270861(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:O00444|rcsb pdb:2N19|rcsb pdb:3COK|rcsb pdb:4JXF|rcsb pdb:4N7V|rcsb pdb:4N7Z|rcsb pdb:4N9J|rcsb pdb:4YUR|rcsb pdb:4YYP refseq:NP_001191395.1|refseq:NP_001191396.1|refseq:NP_005667.2|refseq:NP_690595.1|refseq:NP_001191397.1|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR033095|interpro:IPR034992|interpro:IPR035618|interpro:IPR035979|interpro:IPR036443|interpro:IPR041591|mint:P98175|rcsb pdb:2LXI|rcsb pdb:2M2B|rcsb pdb:2MXV|rcsb pdb:2MXW|rcsb pdb:5ZSW|rcsb pdb:5ZSY|ensembl:ENSG00000182872(gene)|ensembl:ENST00000377604(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016607"(nuclear speck)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034393"(positive regulation of smooth muscle cell apoptotic process)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|interpro:IPR000467(D111/G-patch)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait) - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xqjVEnoGXDk/+2AzLRAkyPK80OI9606 rogid:LOhPGCjbvCh2MDG5JRHlrMrElW49606 rigid:lbKLlozX9PaMOzH1CB/kW5Zt8no false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00444 uniprotkb:P46821 intact:EBI-746202|uniprotkb:Q8IYF0|uniprotkb:Q96Q95|uniprotkb:B2RAL0|uniprotkb:B7Z837|uniprotkb:B7Z8G7|uniprotkb:Q9UD84|uniprotkb:Q9UDE2|ensembl:ENSP00000270861 intact:EBI-764611|uniprotkb:A2BDK5|ensembl:ENSP00000296755 psi-mi:plk4_human(display_long)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym)|uniprotkb:PLK4(gene name)|psi-mi:PLK4(display_short)|uniprotkb:SAK(gene name synonym)|uniprotkb:STK18(gene name synonym) psi-mi:map1b_human(display_long)|uniprotkb:MAP1B(gene name)|psi-mi:MAP1B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482559|imex:IM-26985-197 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177728.1|refseq:NP_001177730.1|refseq:NP_055079.3|dip:DIP-34467N|rcsb pdb:5LHZ|rcsb pdb:6N45|rcsb pdb:6N46|rcsb pdb:6W38|rcsb pdb:6W3I|rcsb pdb:6W3J|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|rcsb pdb:5LHY|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000142731(gene)|ensembl:ENST00000270861(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:O00444|rcsb pdb:2N19|rcsb pdb:3COK|rcsb pdb:4JXF|rcsb pdb:4N7V|rcsb pdb:4N7Z|rcsb pdb:4N9J|rcsb pdb:4YUR|rcsb pdb:4YYP refseq:NP_005900.2|dip:DIP-33474N|ensembl:ENSG00000131711(gene)|ensembl:ENST00000296755(transcript)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001764"(neuron migration)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007416"(synapse assembly)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009987"(cellular process)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016358"(dendrite development)|go:"GO:0021700"(developmental maturation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031114"(regulation of microtubule depolymerization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0032355"(response to estradiol)|go:"GO:0032387"(negative regulation of intracellular transport)|go:"GO:0033189"(response to vitamin A)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042493"|go:"GO:0043025"(neuronal cell body)|go:"GO:0043196"(varicosity)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0017085"(response to insecticide)|go:"GO:0045202"(synapse)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0051915"(induction of synaptic plasticity by chemical substance)|go:"GO:0061162"(establishment of monopolar cell polarity)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0097440"(apical dendrite)|go:"GO:0097441"(basal dendrite)|go:"GO:0097457"(hippocampal mossy fiber)|interpro:IPR000102(Neuraxin/MAP1B repeat)|go:"GO:0044877"(protein-containing complex binding)|interpro:IPR027321|mint:P46821|interpro:IPR026074 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xqjVEnoGXDk/+2AzLRAkyPK80OI9606 rogid:uSRzrWaYU/dmkItUkCK4zex+/TM9606 rigid:lbKLlozX9PaMOzH1CB/kW5Zt8no false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00444 uniprotkb:Q15208 intact:EBI-746202|uniprotkb:Q8IYF0|uniprotkb:Q96Q95|uniprotkb:B2RAL0|uniprotkb:B7Z837|uniprotkb:B7Z8G7|uniprotkb:Q9UD84|uniprotkb:Q9UDE2|ensembl:ENSP00000270861 intact:EBI-458376|ensembl:ENSP00000229812|uniprotkb:Q503A1 psi-mi:plk4_human(display_long)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym)|uniprotkb:PLK4(gene name)|psi-mi:PLK4(display_short)|uniprotkb:SAK(gene name synonym)|uniprotkb:STK18(gene name synonym) psi-mi:stk38_human(display_long)|uniprotkb:NDR1(gene name synonym)|uniprotkb:STK38(gene name)|psi-mi:STK38(display_short)|uniprotkb:NDR1 protein kinase(gene name synonym)|uniprotkb:Nuclear Dbf2-related kinase 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482559|imex:IM-26985-197 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177728.1|refseq:NP_001177730.1|refseq:NP_055079.3|dip:DIP-34467N|rcsb pdb:5LHZ|rcsb pdb:6N45|rcsb pdb:6N46|rcsb pdb:6W38|rcsb pdb:6W3I|rcsb pdb:6W3J|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|rcsb pdb:5LHY|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000142731(gene)|ensembl:ENST00000270861(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:O00444|rcsb pdb:2N19|rcsb pdb:3COK|rcsb pdb:4JXF|rcsb pdb:4N7V|rcsb pdb:4N7Z|rcsb pdb:4N9J|rcsb pdb:4YUR|rcsb pdb:4YYP ensembl:ENSG00000112079(gene)|ensembl:ENST00000229812(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|mint:Q15208|rcsb pdb:1PSB|rcsb pdb:6BXI|reactome:R-HSA-9013418|reactome:R-HSA-9013422|refseq:NP_009202.1|refseq:XP_006715051.1|refseq:XP_006715052.1|refseq:NP_001292031.1 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xqjVEnoGXDk/+2AzLRAkyPK80OI9606 rogid:YHzdDrPEH6YdhOXtcnLWArqftck9606 rigid:lbKLlozX9PaMOzH1CB/kW5Zt8no false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00444 uniprotkb:P84090 intact:EBI-746202|uniprotkb:Q8IYF0|uniprotkb:Q96Q95|uniprotkb:B2RAL0|uniprotkb:B7Z837|uniprotkb:B7Z8G7|uniprotkb:Q9UD84|uniprotkb:Q9UDE2|ensembl:ENSP00000270861 intact:EBI-711389|uniprotkb:P70659|uniprotkb:Q14259|ensembl:ENSP00000451080|uniprotkb:B2R5H2 psi-mi:plk4_human(display_long)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym)|uniprotkb:PLK4(gene name)|psi-mi:PLK4(display_short)|uniprotkb:SAK(gene name synonym)|uniprotkb:STK18(gene name synonym) psi-mi:erh_human(display_long)|uniprotkb:ERH(gene name)|psi-mi:ERH(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482559|imex:IM-26985-197 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177728.1|refseq:NP_001177730.1|refseq:NP_055079.3|dip:DIP-34467N|rcsb pdb:5LHZ|rcsb pdb:6N45|rcsb pdb:6N46|rcsb pdb:6W38|rcsb pdb:6W3I|rcsb pdb:6W3J|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|rcsb pdb:5LHY|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000142731(gene)|ensembl:ENST00000270861(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:O00444|rcsb pdb:2N19|rcsb pdb:3COK|rcsb pdb:4JXF|rcsb pdb:4N7V|rcsb pdb:4N7Z|rcsb pdb:4N9J|rcsb pdb:4YUR|rcsb pdb:4YYP ensembl:ENSG00000100632(gene)|ensembl:ENST00000557016(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006213"(pyrimidine nucleoside metabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0030496"(midbody)|go:"GO:0034709"(methylosome)|interpro:IPR000781(Enhancer of rudimentary)|interpro:IPR035912|mint:P84090|rcsb pdb:1W9G|rcsb pdb:2NML|rcsb pdb:7CNC|refseq:NP_004441.1|dip:DIP-42473N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xqjVEnoGXDk/+2AzLRAkyPK80OI9606 rogid:foMOmvZ9wQyH0rrzBB2YlQhrT0g9606 rigid:lbKLlozX9PaMOzH1CB/kW5Zt8no false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00444 uniprotkb:O75533 intact:EBI-746202|uniprotkb:Q8IYF0|uniprotkb:Q96Q95|uniprotkb:B2RAL0|uniprotkb:B7Z837|uniprotkb:B7Z8G7|uniprotkb:Q9UD84|uniprotkb:Q9UDE2|ensembl:ENSP00000270861 intact:EBI-876542|ensembl:ENSP00000335321|uniprotkb:E9PCH3 psi-mi:plk4_human(display_long)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym)|uniprotkb:PLK4(gene name)|psi-mi:PLK4(display_short)|uniprotkb:SAK(gene name synonym)|uniprotkb:STK18(gene name synonym) psi-mi:sf3b1_human(display_long)|uniprotkb:Pre-mRNA-splicing factor SF3b 155 kDa subunit(gene name synonym)|uniprotkb:Spliceosome-associated protein 155(gene name synonym)|uniprotkb:SF3B1(gene name)|psi-mi:SF3B1(display_short)|uniprotkb:SAP155(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482559|imex:IM-26985-197 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177728.1|refseq:NP_001177730.1|refseq:NP_055079.3|dip:DIP-34467N|rcsb pdb:5LHZ|rcsb pdb:6N45|rcsb pdb:6N46|rcsb pdb:6W38|rcsb pdb:6W3I|rcsb pdb:6W3J|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|rcsb pdb:5LHY|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000142731(gene)|ensembl:ENST00000270861(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:O00444|rcsb pdb:2N19|rcsb pdb:3COK|rcsb pdb:4JXF|rcsb pdb:4N7V|rcsb pdb:4N7Z|rcsb pdb:4N9J|rcsb pdb:4YUR|rcsb pdb:4YYP ensembl:ENSG00000115524(gene)|ensembl:ENST00000335508(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0034693"(U11/U12 snRNP)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR015016(Splicing factor 3B subunit 1)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR038737|mint:O75533|rcsb pdb:2F9D|rcsb pdb:2F9J|rcsb pdb:2FHO|rcsb pdb:2PEH|rcsb pdb:3LQV|rcsb pdb:4OZ1|rcsb pdb:5IFE|rcsb pdb:5O9Z|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:5ZYA|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6N3E|refseq:NP_036565.2|dip:DIP-29411N|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-5250924|reactome:R-HSA-72163|reactome:R-HSA-72165 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xqjVEnoGXDk/+2AzLRAkyPK80OI9606 rogid:2KqZNVdZoItavA0DFR3zZ16U0tI9606 rigid:lbKLlozX9PaMOzH1CB/kW5Zt8no false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00444 uniprotkb:O75688 intact:EBI-746202|uniprotkb:Q8IYF0|uniprotkb:Q96Q95|uniprotkb:B2RAL0|uniprotkb:B7Z837|uniprotkb:B7Z8G7|uniprotkb:Q9UD84|uniprotkb:Q9UDE2|ensembl:ENSP00000270861 intact:EBI-1047039|uniprotkb:Q9HAY8|uniprotkb:Q461Q2|uniprotkb:Q658R4|ensembl:ENSP00000282412|uniprotkb:Q96ER6|uniprotkb:Q4J6C1|uniprotkb:Q4J6C2 psi-mi:plk4_human(display_long)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym)|uniprotkb:PLK4(gene name)|psi-mi:PLK4(display_short)|uniprotkb:SAK(gene name synonym)|uniprotkb:STK18(gene name synonym) psi-mi:ppm1b_human(display_long)|uniprotkb:Protein phosphatase 2C isoform beta(gene name synonym)|uniprotkb:PPM1B(gene name)|psi-mi:PPM1B(display_short)|uniprotkb:PP2CB(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482559|imex:IM-26985-197 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177728.1|refseq:NP_001177730.1|refseq:NP_055079.3|dip:DIP-34467N|rcsb pdb:5LHZ|rcsb pdb:6N45|rcsb pdb:6N46|rcsb pdb:6W38|rcsb pdb:6W3I|rcsb pdb:6W3J|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|rcsb pdb:5LHY|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000142731(gene)|ensembl:ENST00000270861(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:O00444|rcsb pdb:2N19|rcsb pdb:3COK|rcsb pdb:4JXF|rcsb pdb:4N7V|rcsb pdb:4N7Z|rcsb pdb:4N9J|rcsb pdb:4YUR|rcsb pdb:4YYP refseq:NP_001028729.1|refseq:NP_002697.1|refseq:NP_808907.1|refseq:NP_808908.1|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|interpro:IPR000222(Protein phosphatase 2C, manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR012911(Protein serine/threonine phosphatase 2C, C-terminal)|interpro:IPR036457|interpro:IPR036580|mint:O75688|rcsb pdb:2P8E|reactome:R-HSA-1169408|ensembl:ENSG00000138032(gene)|ensembl:ENST00000282412(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006499"(N-terminal protein myristoylation)|go:"GO:0016020"(membrane)|go:"GO:0030145"(manganese ion binding)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0035970"(peptidyl-threonine dephosphorylation) - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xqjVEnoGXDk/+2AzLRAkyPK80OI9606 rogid:cwwfGSSTv9pR/XNLa9UxQ/6hpD89606 rigid:lbKLlozX9PaMOzH1CB/kW5Zt8no false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00444 uniprotkb:P54105 intact:EBI-746202|uniprotkb:Q8IYF0|uniprotkb:Q96Q95|uniprotkb:B2RAL0|uniprotkb:B7Z837|uniprotkb:B7Z8G7|uniprotkb:Q9UD84|uniprotkb:Q9UDE2|ensembl:ENSP00000270861 intact:EBI-724693|uniprotkb:Q0VDK6|uniprotkb:Q9NRD2|uniprotkb:Q9NRD3|uniprotkb:B2RCS9|ensembl:ENSP00000433919|ensembl:ENSP00000434311 psi-mi:plk4_human(display_long)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym)|uniprotkb:PLK4(gene name)|psi-mi:PLK4(display_short)|uniprotkb:SAK(gene name synonym)|uniprotkb:STK18(gene name synonym) psi-mi:icln_human(display_long)|uniprotkb:Chloride conductance regulatory protein ICln(gene name synonym)|uniprotkb:Chloride channel, nucleotide sensitive 1A(gene name synonym)|uniprotkb:Chloride ion current inducer protein(gene name synonym)|uniprotkb:Reticulocyte pICln(gene name synonym)|uniprotkb:CLNS1A(gene name)|psi-mi:CLNS1A(display_short)|uniprotkb:ICLN(gene name synonym)|uniprotkb:CLCI(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482559|imex:IM-26985-197 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177728.1|refseq:NP_001177730.1|refseq:NP_055079.3|dip:DIP-34467N|rcsb pdb:5LHZ|rcsb pdb:6N45|rcsb pdb:6N46|rcsb pdb:6W38|rcsb pdb:6W3I|rcsb pdb:6W3J|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|rcsb pdb:5LHY|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000142731(gene)|ensembl:ENST00000270861(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:O00444|rcsb pdb:2N19|rcsb pdb:3COK|rcsb pdb:4JXF|rcsb pdb:4N7V|rcsb pdb:4N7Z|rcsb pdb:4N9J|rcsb pdb:4YUR|rcsb pdb:4YYP refseq:NP_001284.1|refseq:NP_001298128.1|refseq:NP_001298129.1|refseq:NP_001298130.1|refseq:NP_001298131.1|ensembl:ENSG00000074201(gene)|ensembl:ENST00000525428(transcript)|ensembl:ENST00000528364(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006821"(chloride transport)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|interpro:IPR003521(Nucleotide-sensitive chloride conductance regulator)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039924|mint:P54105|rcsb pdb:6V0O|reactome:R-HSA-191859|dip:DIP-44185N - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xqjVEnoGXDk/+2AzLRAkyPK80OI9606 rogid:dGx9UwPj9VBp1CiPTRCXnT3IYt89606 rigid:lbKLlozX9PaMOzH1CB/kW5Zt8no false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00444 uniprotkb:P12821 intact:EBI-746202|uniprotkb:Q8IYF0|uniprotkb:Q96Q95|uniprotkb:B2RAL0|uniprotkb:B7Z837|uniprotkb:B7Z8G7|uniprotkb:Q9UD84|uniprotkb:Q9UDE2|ensembl:ENSP00000270861 intact:EBI-9512350|uniprotkb:B0LPF0|uniprotkb:B4DXI3|uniprotkb:E7EU16|uniprotkb:P22966|uniprotkb:Q53YX9|uniprotkb:Q59GY8|uniprotkb:Q7M4L4|ensembl:ENSP00000290866 psi-mi:plk4_human(display_long)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym)|uniprotkb:PLK4(gene name)|psi-mi:PLK4(display_short)|uniprotkb:SAK(gene name synonym)|uniprotkb:STK18(gene name synonym) psi-mi:ace_human(display_long)|uniprotkb:ACE(gene name)|psi-mi:ACE(display_short)|uniprotkb:DCP(gene name synonym)|uniprotkb:DCP1(gene name synonym)|uniprotkb:Dipeptidyl carboxypeptidase I(gene name synonym)|uniprotkb:Kininase II(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482559|imex:IM-26985-197 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177728.1|refseq:NP_001177730.1|refseq:NP_055079.3|dip:DIP-34467N|rcsb pdb:5LHZ|rcsb pdb:6N45|rcsb pdb:6N46|rcsb pdb:6W38|rcsb pdb:6W3I|rcsb pdb:6W3J|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|rcsb pdb:5LHY|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000142731(gene)|ensembl:ENST00000270861(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:O00444|rcsb pdb:2N19|rcsb pdb:3COK|rcsb pdb:4JXF|rcsb pdb:4N7V|rcsb pdb:4N7Z|rcsb pdb:4N9J|rcsb pdb:4YUR|rcsb pdb:4YYP refseq:NP_000780.1|refseq:NP_001171528.1|refseq:NP_690043.1|ensembl:ENSG00000159640(gene)|ensembl:ENST00000290866(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002003"(angiotensin maturation)|go:"GO:0002019"(regulation of renal output by angiotensin)|go:"GO:0002446"(neutrophil mediated immunity)|go:"GO:0002474"(antigen processing and presentation of peptide antigen via MHC class I)|go:"GO:0003081"(regulation of systemic arterial blood pressure by renin-angiotensin)|go:"GO:0003084"(positive regulation of systemic arterial blood pressure)|go:"GO:0003779"(actin binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0008238"(exopeptidase activity)|go:"GO:0008240"(tripeptidyl-peptidase activity)|go:"GO:0008241"(peptidyl-dipeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014910"(regulation of smooth muscle cell migration)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019229"(regulation of vasoconstriction)|go:"GO:0031404"(chloride ion binding)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031711"(bradykinin receptor binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032943"(mononuclear cell proliferation)|go:"GO:0042447"(hormone catabolic process)|go:"GO:0043171"(peptide catabolic process)|go:"GO:0050435"(amyloid-beta metabolic process)|go:"GO:0050482"(arachidonic acid secretion)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0060047"(heart contraction)|go:"GO:0060177"(regulation of angiotensin metabolic process)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070573"(metallodipeptidase activity)|go:"GO:0071838"(cell proliferation in bone marrow)|go:"GO:0097746"(blood vessel diameter maintenance)|go:"GO:1900086"(positive regulation of peptidyl-tyrosine autophosphorylation)|go:"GO:1902033"(regulation of hematopoietic stem cell proliferation)|go:"GO:1903597"(negative regulation of gap junction assembly)|go:"GO:2000170"(positive regulation of peptidyl-cysteine S-nitrosylation)|interpro:IPR001548(Peptidase M2, peptidyl-dipeptidase A)|mint:P12821|rcsb pdb:1O86|rcsb pdb:1O8A|rcsb pdb:1UZE|rcsb pdb:1UZF|rcsb pdb:2C6F|rcsb pdb:2C6N|rcsb pdb:2IUL|rcsb pdb:2IUX|rcsb pdb:2OC2|rcsb pdb:2XY9|rcsb pdb:2XYD|rcsb pdb:2YDM|rcsb pdb:3BKK|rcsb pdb:3BKL|rcsb pdb:3L3N|rcsb pdb:3NXQ|rcsb pdb:4APH|rcsb pdb:4APJ|rcsb pdb:4BXK|rcsb pdb:4BZR|rcsb pdb:4BZS|rcsb pdb:4C2N|rcsb pdb:4C2O|rcsb pdb:4C2P|rcsb pdb:4C2Q|rcsb pdb:4C2R|rcsb pdb:4CA5|rcsb pdb:4CA6|rcsb pdb:4UFA|rcsb pdb:4UFB|rcsb pdb:5AM8|rcsb pdb:5AM9|rcsb pdb:5AMA|rcsb pdb:5AMB|rcsb pdb:5AMC|rcsb pdb:6EN5|rcsb pdb:6EN6|rcsb pdb:6F9R|rcsb pdb:6F9T|rcsb pdb:6F9U|rcsb pdb:6F9V|rcsb pdb:6H5W|rcsb pdb:6H5X|rcsb pdb:6QS1|rcsb pdb:6TT1|rcsb pdb:6TT3|rcsb pdb:6TT4|rcsb pdb:6ZPQ|rcsb pdb:6ZPT|rcsb pdb:6ZPU|reactome:R-HSA-2022377 - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xqjVEnoGXDk/+2AzLRAkyPK80OI9606 rogid:Ta44N/vjlStlVIzNX634OjHzyrM9606 rigid:lbKLlozX9PaMOzH1CB/kW5Zt8no false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00444 uniprotkb:P68363 intact:EBI-746202|uniprotkb:Q8IYF0|uniprotkb:Q96Q95|uniprotkb:B2RAL0|uniprotkb:B7Z837|uniprotkb:B7Z8G7|uniprotkb:Q9UD84|uniprotkb:Q9UDE2|ensembl:ENSP00000270861 intact:EBI-487083|intact:EBI-1384226|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:Q27I68|ensembl:ENSP00000336799|uniprotkb:Q8WU19 psi-mi:plk4_human(display_long)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym)|uniprotkb:PLK4(gene name)|psi-mi:PLK4(display_short)|uniprotkb:SAK(gene name synonym)|uniprotkb:STK18(gene name synonym) psi-mi:tba1b_human(display_long)|uniprotkb:TUBA1B(gene name)|psi-mi:TUBA1B(display_short)|uniprotkb:Tubulin alpha-ubiquitous chain(gene name synonym)|uniprotkb:Alpha-tubulin ubiquitous(gene name synonym)|uniprotkb:Tubulin K-alpha-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482559|imex:IM-26985-197 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177728.1|refseq:NP_001177730.1|refseq:NP_055079.3|dip:DIP-34467N|rcsb pdb:5LHZ|rcsb pdb:6N45|rcsb pdb:6N46|rcsb pdb:6W38|rcsb pdb:6W3I|rcsb pdb:6W3J|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|rcsb pdb:5LHY|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000142731(gene)|ensembl:ENST00000270861(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:O00444|rcsb pdb:2N19|rcsb pdb:3COK|rcsb pdb:4JXF|rcsb pdb:4N7V|rcsb pdb:4N7Z|rcsb pdb:4N9J|rcsb pdb:4YUR|rcsb pdb:4YYP refseq:NP_006073.2|ensembl:ENSG00000123416(gene)|ensembl:ENST00000336023(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-983189|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|go:"GO:0045121"(membrane raft)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68363|rcsb pdb:2E4H|rcsb pdb:5IJ0|rcsb pdb:5IJ9|rcsb pdb:5N5N|rcsb pdb:6E7B|rcsb pdb:6E7C|rcsb pdb:6I2I|go:"GO:0051301"(cell division)|rcsb pdb:6J4V|rcsb pdb:6J8O|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|rcsb pdb:6S8L|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9013407|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-2132295|reactome:R-HSA-9668328 - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xqjVEnoGXDk/+2AzLRAkyPK80OI9606 rogid:D4YpuLCXl/S+53qV7P7sF81aARY9606 rigid:lbKLlozX9PaMOzH1CB/kW5Zt8no false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00444 uniprotkb:P04745 intact:EBI-746202|uniprotkb:Q8IYF0|uniprotkb:Q96Q95|uniprotkb:B2RAL0|uniprotkb:B7Z837|uniprotkb:B7Z8G7|uniprotkb:Q9UD84|uniprotkb:Q9UDE2|ensembl:ENSP00000270861 intact:EBI-738586|uniprotkb:Q13763|uniprotkb:A6NJS5|uniprotkb:A8K8H6|uniprotkb:Q5T083 psi-mi:plk4_human(display_long)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym)|uniprotkb:PLK4(gene name)|psi-mi:PLK4(display_short)|uniprotkb:SAK(gene name synonym)|uniprotkb:STK18(gene name synonym) psi-mi:amy1a_human(display_long)|uniprotkb:AMY1A(gene name)|psi-mi:AMY1A(display_short)|uniprotkb:AMY1(gene name synonym)|uniprotkb:1,4-alpha-D-glucan glucanohydrolase 1(gene name synonym)|uniprotkb:Salivary alpha-amylase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482559|imex:IM-26985-197 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177728.1|refseq:NP_001177730.1|refseq:NP_055079.3|dip:DIP-34467N|rcsb pdb:5LHZ|rcsb pdb:6N45|rcsb pdb:6N46|rcsb pdb:6W38|rcsb pdb:6W3I|rcsb pdb:6W3J|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|rcsb pdb:5LHY|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000142731(gene)|ensembl:ENST00000270861(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:O00444|rcsb pdb:2N19|rcsb pdb:3COK|rcsb pdb:4JXF|rcsb pdb:4N7V|rcsb pdb:4N7Z|rcsb pdb:4N9J|rcsb pdb:4YUR|rcsb pdb:4YYP ensembl:ENST00000330330|ensembl:ENST00000370079|ensembl:ENST00000370080|ensembl:ENST00000370083|refseq:NP_001008219.1|refseq:NP_001008220.1|refseq:NP_001008222.1|refseq:NP_004029.2|interpro:IPR006048(Alpha-amylase, C-terminal all beta)|interpro:IPR006046(Glycoside hydrolase family 13)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|go:"GO:0004556"(alpha-amylase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0005975"(carbohydrate metabolic process)|rcsb pdb:1C8Q|rcsb pdb:1JXJ|rcsb pdb:1JXK|rcsb pdb:1MFU|rcsb pdb:1MFV|rcsb pdb:1NM9|rcsb pdb:1Q4N|rcsb pdb:1SMD|rcsb pdb:1XV8|rcsb pdb:1Z32|rcsb pdb:3BLK|rcsb pdb:3BLP|rcsb pdb:3DHP|refseq:XP_016856547.1|interpro:IPR031319|reactome:R-HSA-189085|go:"GO:0005615"(extracellular space)|go:"GO:0070062"(extracellular exosome)|refseq:XP_011539564.1|refseq:NP_001333709.1|ensembl:ENSG00000174876|ensembl:ENSG00000187733|ensembl:ENSG00000237763|ensembl:ENSP00000330484|ensembl:ENSP00000359096|ensembl:ENSP00000359097|ensembl:ENSP00000359100|go:"GO:0103025"|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta) - - caution:This sequence has been withdrawn from Uniprot.|comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xqjVEnoGXDk/+2AzLRAkyPK80OI9606 rogid:Gwt64Wrt6IUZmCIxM3CXQxe7W509606 rigid:lbKLlozX9PaMOzH1CB/kW5Zt8no false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00444 uniprotkb:P04908 intact:EBI-746202|uniprotkb:Q8IYF0|uniprotkb:Q96Q95|uniprotkb:B2RAL0|uniprotkb:B7Z837|uniprotkb:B7Z8G7|uniprotkb:Q9UD84|uniprotkb:Q9UDE2|ensembl:ENSP00000270861 intact:EBI-358971|uniprotkb:Q76P63|uniprotkb:P28001|ensembl:ENSP00000303373|ensembl:ENSP00000483842 psi-mi:plk4_human(display_long)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym)|uniprotkb:PLK4(gene name)|psi-mi:PLK4(display_short)|uniprotkb:SAK(gene name synonym)|uniprotkb:STK18(gene name synonym) psi-mi:h2a1b_human(display_long)|uniprotkb:H2AC4(gene name)|psi-mi:H2AC4(display_short)|uniprotkb:H2AC8(gene name)|psi-mi:H2AC8(display_short)|uniprotkb:H2AFA(gene name synonym)|uniprotkb:H2AFM(gene name synonym)|uniprotkb:HIST1H2AB(gene name synonym)|uniprotkb:HIST1H2AE(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/a(gene name synonym)|uniprotkb:Histone H2A/m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482559|imex:IM-26985-197 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177728.1|refseq:NP_001177730.1|refseq:NP_055079.3|dip:DIP-34467N|rcsb pdb:5LHZ|rcsb pdb:6N45|rcsb pdb:6N46|rcsb pdb:6W38|rcsb pdb:6W3I|rcsb pdb:6W3J|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|rcsb pdb:5LHY|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000142731(gene)|ensembl:ENST00000270861(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:O00444|rcsb pdb:2N19|rcsb pdb:3COK|rcsb pdb:4JXF|rcsb pdb:4N7V|rcsb pdb:4N7Z|rcsb pdb:4N9J|rcsb pdb:4YUR|rcsb pdb:4YYP refseq:NP_003504.2|refseq:NP_066390.1|ensembl:ENSG00000277075(gene)|ensembl:ENSG00000278463(gene)|ensembl:ENST00000303910(transcript)|ensembl:ENST00000615868(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P04908|rcsb pdb:2CV5|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1V|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACL|rcsb pdb:6AEE|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6KE9|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V92|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|rcsb pdb:6JXD|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|dip:DIP-44197N - - comment:"author score: 32" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xqjVEnoGXDk/+2AzLRAkyPK80OI9606 rogid:4Qno1mMYZB6FdNoojrzulWLVq849606 rigid:lbKLlozX9PaMOzH1CB/kW5Zt8no false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00444 uniprotkb:Q15427 intact:EBI-746202|uniprotkb:Q8IYF0|uniprotkb:Q96Q95|uniprotkb:B2RAL0|uniprotkb:B7Z837|uniprotkb:B7Z8G7|uniprotkb:Q9UD84|uniprotkb:Q9UDE2|ensembl:ENSP00000270861 intact:EBI-348469|ensembl:ENSP00000271628|intact:EBI-1047735|uniprotkb:Q5SZ63 psi-mi:plk4_human(display_long)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym)|uniprotkb:PLK4(gene name)|psi-mi:PLK4(display_short)|uniprotkb:SAK(gene name synonym)|uniprotkb:STK18(gene name synonym) psi-mi:sf3b4_human(display_long)|uniprotkb:SF3B4(gene name)|psi-mi:SF3B4(display_short)|uniprotkb:SAP49(gene name synonym)|uniprotkb:Spliceosome-associated protein 49(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 49 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482559|imex:IM-26985-197 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177728.1|refseq:NP_001177730.1|refseq:NP_055079.3|dip:DIP-34467N|rcsb pdb:5LHZ|rcsb pdb:6N45|rcsb pdb:6N46|rcsb pdb:6W38|rcsb pdb:6W3I|rcsb pdb:6W3J|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|rcsb pdb:5LHY|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000142731(gene)|ensembl:ENST00000270861(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:O00444|rcsb pdb:2N19|rcsb pdb:3COK|rcsb pdb:4JXF|rcsb pdb:4N7V|rcsb pdb:4N7Z|rcsb pdb:4N9J|rcsb pdb:4YUR|rcsb pdb:4YYP refseq:NP_005841.1|ensembl:ENSG00000143368(gene)|ensembl:ENST00000271628(transcript)|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|rcsb pdb:6AHD|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034158|go:"GO:0000375"(RNA splicing, via transesterification reactions)|interpro:IPR034159|interpro:IPR035979|mint:Q15427|rcsb pdb:1X5T|rcsb pdb:5GVQ|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0 - - comment:"author score: 35" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xqjVEnoGXDk/+2AzLRAkyPK80OI9606 rogid:Jgy6WmBFKkphpZLLte2GgsagUVI9606 rigid:lbKLlozX9PaMOzH1CB/kW5Zt8no false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00444 uniprotkb:P16403 intact:EBI-746202|uniprotkb:Q8IYF0|uniprotkb:Q96Q95|uniprotkb:B2RAL0|uniprotkb:B7Z837|uniprotkb:B7Z8G7|uniprotkb:Q9UD84|uniprotkb:Q9UDE2|ensembl:ENSP00000270861 intact:EBI-358372|ensembl:ENSP00000339566|uniprotkb:A8K4I2 psi-mi:plk4_human(display_long)|uniprotkb:Polo-like kinase 4(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Sak(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 18(gene name synonym)|uniprotkb:PLK4(gene name)|psi-mi:PLK4(display_short)|uniprotkb:SAK(gene name synonym)|uniprotkb:STK18(gene name synonym) psi-mi:h12_human(display_long)|uniprotkb:H1-2(gene name)|psi-mi:H1-2(display_short)|uniprotkb:H1F2(gene name synonym)|uniprotkb:HIST1H1C(gene name synonym)|uniprotkb:Histone H1c(gene name synonym)|uniprotkb:Histone H1d(gene name synonym)|uniprotkb:Histone H1s-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482559|imex:IM-26985-197 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001177728.1|refseq:NP_001177730.1|refseq:NP_055079.3|dip:DIP-34467N|rcsb pdb:5LHZ|rcsb pdb:6N45|rcsb pdb:6N46|rcsb pdb:6W38|rcsb pdb:6W3I|rcsb pdb:6W3J|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|rcsb pdb:5LHY|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000142731(gene)|ensembl:ENST00000270861(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0001741"(XY body)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007099"(centriole replication)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0046601"(positive regulation of centriole replication)|go:"GO:0060271"(cilium assembly)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0098535"(de novo centriole assembly involved in multi-ciliated epithelial cell differentiation)|go:"GO:0098536"(deuterosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033696|interpro:IPR033698|interpro:IPR033699|interpro:IPR033700|mint:O00444|rcsb pdb:2N19|rcsb pdb:3COK|rcsb pdb:4JXF|rcsb pdb:4N7V|rcsb pdb:4N7Z|rcsb pdb:4N9J|rcsb pdb:4YUR|rcsb pdb:4YYP refseq:NP_005310.1|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P16403|reactome:R-HSA-140342|reactome:R-HSA-2559584|ensembl:ENSG00000187837(gene)|ensembl:ENST00000343677(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|dip:DIP-36359N - - comment:"author score: 36" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xqjVEnoGXDk/+2AzLRAkyPK80OI9606 rogid:eRT5bTyBJUg6nRANMRYZekT4N+g9606 rigid:lbKLlozX9PaMOzH1CB/kW5Zt8no false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7Z3Z4 uniprotkb:Q5T749 intact:EBI-528601|uniprotkb:Q68CZ4|uniprotkb:Q8N8G9|uniprotkb:Q8N9V8|uniprotkb:Q8NEH2|uniprotkb:B4DEG5|ensembl:ENSP00000299001 intact:EBI-10981970|ensembl:ENSP00000475216 psi-mi:piwl4_human(display_long)|uniprotkb:PIWIL4(gene name)|psi-mi:PIWIL4(display_short)|uniprotkb:HIWI2(gene name synonym)|uniprotkb:PIWI(gene name synonym) psi-mi:kprp_human(display_long)|uniprotkb:KPRP(gene name)|psi-mi:KPRP(display_short)|uniprotkb:C1orf45(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482538|imex:IM-26985-125 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_689644.2|ensembl:ENST00000299001(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0030154"(cell differentiation)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0034584"(piRNA binding)|go:"GO:0034587"(piRNA metabolic process)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0043186"(P granule)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0071547"(piP-body)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036085|interpro:IPR036397|mint:Q7Z3Z4|reactome:R-HSA-5601884|ensembl:ENSG00000134627(gene) refseq:NP_001020402.1|refseq:XP_011507873.1|ensembl:ENSG00000203786(gene)|ensembl:ENST00000606109(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0070062"(extracellular exosome)|mint:Q5T749 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wcvVa2Z0CqemBieD8X12ovmdfpc9606 rogid:y5a5hbvzlv8VDmCY169of+RrNKo9606 rigid:ULkXxqUZasN3NwFLEIpypCMFIO4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7Z3Z4 uniprotkb:Q01469 intact:EBI-528601|uniprotkb:Q68CZ4|uniprotkb:Q8N8G9|uniprotkb:Q8N9V8|uniprotkb:Q8NEH2|uniprotkb:B4DEG5|ensembl:ENSP00000299001 intact:EBI-1054073|uniprotkb:B2R4K0|ensembl:ENSP00000297258 psi-mi:piwl4_human(display_long)|uniprotkb:PIWIL4(gene name)|psi-mi:PIWIL4(display_short)|uniprotkb:HIWI2(gene name synonym)|uniprotkb:PIWI(gene name synonym) psi-mi:fabp5_human(display_long)|uniprotkb:Epidermal-type fatty acid-binding protein(gene name synonym)|uniprotkb:Psoriasis-associated fatty acid-binding protein homolog(gene name synonym)|uniprotkb:FABP5(gene name)|psi-mi:FABP5(display_short)|uniprotkb:Fatty acid-binding protein, epidermal(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482538|imex:IM-26985-125 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_689644.2|ensembl:ENST00000299001(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0030154"(cell differentiation)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0034584"(piRNA binding)|go:"GO:0034587"(piRNA metabolic process)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0043186"(P granule)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0071547"(piP-body)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036085|interpro:IPR036397|mint:Q7Z3Z4|reactome:R-HSA-5601884|ensembl:ENSG00000134627(gene) refseq:NP_001435.1|ensembl:ENSG00000164687(gene)|ensembl:ENST00000297258(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0008289"(lipid binding)|go:"GO:0008544"(epidermis development)|go:"GO:0010829"(negative regulation of glucose transmembrane transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031392"(regulation of prostaglandin biosynthetic process)|go:"GO:0035360"(positive regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099178"(regulation of retrograde trans-synaptic signaling by endocanabinoid)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990379"(lipid transport across blood-brain barrier)|interpro:IPR000463(Cytosolic fatty-acid binding)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR012674(Calycin)|interpro:IPR031259|mint:Q01469|rcsb pdb:1B56|rcsb pdb:1JJJ|rcsb pdb:4AZM|rcsb pdb:4AZR|rcsb pdb:4LKP|rcsb pdb:4LKT|rcsb pdb:5HZ5|rcsb pdb:5UR9|reactome:R-HSA-163560|reactome:R-HSA-5362517|reactome:R-HSA-6798695 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wcvVa2Z0CqemBieD8X12ovmdfpc9606 rogid:vxp81/mezHcm5oo27QOmAM8Y5dI9606 rigid:ULkXxqUZasN3NwFLEIpypCMFIO4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7Z3Z4 uniprotkb:P81605 intact:EBI-528601|uniprotkb:Q68CZ4|uniprotkb:Q8N8G9|uniprotkb:Q8N9V8|uniprotkb:Q8NEH2|uniprotkb:B4DEG5|ensembl:ENSP00000299001 intact:EBI-395625|uniprotkb:P58461|uniprotkb:A5JHP2|uniprotkb:A5JHP3|uniprotkb:Q53YJ2|ensembl:ENSP00000293371 psi-mi:piwl4_human(display_long)|uniprotkb:PIWIL4(gene name)|psi-mi:PIWIL4(display_short)|uniprotkb:HIWI2(gene name synonym)|uniprotkb:PIWI(gene name synonym) psi-mi:dcd_human(display_long)|uniprotkb:AIDD(gene name synonym)|uniprotkb:DSEP(gene name synonym)|uniprotkb:Preproteolysin(gene name synonym)|uniprotkb:DCD(gene name)|psi-mi:DCD(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482538|imex:IM-26985-125 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_689644.2|ensembl:ENST00000299001(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0030154"(cell differentiation)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0034584"(piRNA binding)|go:"GO:0034587"(piRNA metabolic process)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0043186"(P granule)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0071547"(piP-body)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036085|interpro:IPR036397|mint:Q7Z3Z4|reactome:R-HSA-5601884|ensembl:ENSG00000134627(gene) refseq:NP_444513.1|refseq:NP_001287783.1|ensembl:ENSG00000161634(gene)|ensembl:ENST00000293371(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008233"(peptidase activity)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR028130|interpro:IPR043557|mint:P81605|rcsb pdb:2KSG|rcsb pdb:2NDK|rcsb pdb:2YMK|rcsb pdb:6SHK|reactome:R-HSA-6803157 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wcvVa2Z0CqemBieD8X12ovmdfpc9606 rogid:M8PkKVWx98nhtd79ods05mqw8Ls9606 rigid:ULkXxqUZasN3NwFLEIpypCMFIO4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7Z3Z4 uniprotkb:P01040 intact:EBI-528601|uniprotkb:Q68CZ4|uniprotkb:Q8N8G9|uniprotkb:Q8N9V8|uniprotkb:Q8NEH2|uniprotkb:B4DEG5|ensembl:ENSP00000299001 intact:EBI-724303|ensembl:ENSP00000264474|uniprotkb:Q6IB90 psi-mi:piwl4_human(display_long)|uniprotkb:PIWIL4(gene name)|psi-mi:PIWIL4(display_short)|uniprotkb:HIWI2(gene name synonym)|uniprotkb:PIWI(gene name synonym) psi-mi:cyta_human(display_long)|uniprotkb:Cystatin-AS(gene name synonym)|uniprotkb:Stefin-A(gene name synonym)|uniprotkb:CSTA(gene name)|psi-mi:CSTA(display_short)|uniprotkb:STF1(gene name synonym)|uniprotkb:STFA(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482538|imex:IM-26985-125 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_689644.2|ensembl:ENST00000299001(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0030154"(cell differentiation)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0034584"(piRNA binding)|go:"GO:0034587"(piRNA metabolic process)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0043186"(P granule)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0071547"(piP-body)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036085|interpro:IPR036397|mint:Q7Z3Z4|reactome:R-HSA-5601884|ensembl:ENSG00000134627(gene) refseq:NP_005204.1|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR001713(Proteinase inhibitor I25A, stefin A)|mint:P01040|rcsb pdb:1CYU|rcsb pdb:1CYV|rcsb pdb:1DVC|rcsb pdb:1DVD|rcsb pdb:1GD3|rcsb pdb:1GD4|rcsb pdb:1N9J|rcsb pdb:1NB3|rcsb pdb:1NB5|rcsb pdb:3K9M|rcsb pdb:3KFQ|interpro:IPR018073|rcsb pdb:3KSE|reactome:R-HSA-6809371|ensembl:ENSG00000121552(gene)|ensembl:ENST00000264474(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002020"(protease binding)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0045861"(negative regulation of proteolysis) - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wcvVa2Z0CqemBieD8X12ovmdfpc9606 rogid:SzbpyWUHlOtItIvffzuwhcqFsDI9606 rigid:ULkXxqUZasN3NwFLEIpypCMFIO4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7Z3Z4 uniprotkb:P07477 intact:EBI-528601|uniprotkb:Q68CZ4|uniprotkb:Q8N8G9|uniprotkb:Q8N9V8|uniprotkb:Q8NEH2|uniprotkb:B4DEG5|ensembl:ENSP00000299001 intact:EBI-1222902|uniprotkb:A6NJ71|uniprotkb:Q92955|uniprotkb:Q9HAN4|uniprotkb:Q9HAN5|uniprotkb:Q9HAN6|uniprotkb:Q9HAN7|intact:EBI-1760472|intact:EBI-1965533|uniprotkb:A1A509|uniprotkb:Q5NV57|uniprotkb:Q7M4N3|uniprotkb:Q7M4N4|uniprotkb:B2R5I5|ensembl:ENSP00000308720|ensembl:ENSP00000479217 psi-mi:piwl4_human(display_long)|uniprotkb:PIWIL4(gene name)|psi-mi:PIWIL4(display_short)|uniprotkb:HIWI2(gene name synonym)|uniprotkb:PIWI(gene name synonym) psi-mi:try1_human(display_long)|uniprotkb:PRSS1(gene name)|psi-mi:PRSS1(display_short)|uniprotkb:TRP1(gene name synonym)|uniprotkb:TRY1(gene name synonym)|uniprotkb:TRYP1(gene name synonym)|uniprotkb:Trypsin I(gene name synonym)|uniprotkb:Cationic trypsinogen(gene name synonym)|uniprotkb:Serine protease 1(gene name synonym)|uniprotkb:Beta-trypsin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482538|imex:IM-26985-125 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_689644.2|ensembl:ENST00000299001(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0030154"(cell differentiation)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0034584"(piRNA binding)|go:"GO:0034587"(piRNA metabolic process)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0043186"(P granule)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0071547"(piP-body)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR003100(Argonaute and Dicer protein, PAZ)|interpro:IPR003165(Stem cell self-renewal protein Piwi)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036085|interpro:IPR036397|mint:Q7Z3Z4|reactome:R-HSA-5601884|ensembl:ENSG00000134627(gene) refseq:NP_002760.1|ensembl:ENSG00000204983(gene)|ensembl:ENSG00000274247(gene)|ensembl:ENST00000311737(transcript)|ensembl:ENST00000616256(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0007586"(digestion)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0072562"(blood microparticle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|mint:P07477|rcsb pdb:1FXY|rcsb pdb:1TRN|rcsb pdb:2RA3|rcsb pdb:4WWY|rcsb pdb:4WXV|reactome:R-HSA-1592389|reactome:R-HSA-196741 - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wcvVa2Z0CqemBieD8X12ovmdfpc9606 rogid:2elS/qMYj0sflxilyWfk3KPtGmo9606 rigid:ULkXxqUZasN3NwFLEIpypCMFIO4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15514 uniprotkb:Q9HAN9 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 intact:EBI-3917542|uniprotkb:Q8TAE9|uniprotkb:Q9H6B6|uniprotkb:Q9H247|uniprotkb:B1AN63|ensembl:ENSP00000366410|ensembl:ENSP00000435134 psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:nmna1_human(display_long)|uniprotkb:NMNAT1(gene name)|psi-mi:NMNAT1(display_short)|uniprotkb:NMNAT(gene name synonym)|uniprotkb:Nicotinate-nucleotide adenylyltransferase 1(gene name synonym)|uniprotkb:Nicotinamide-nucleotide adenylyltransferase 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482631|imex:IM-26985-343 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N refseq:NP_001284707.1|refseq:NP_073624.2|ensembl:ENSG00000173614(gene)|ensembl:ENST00000377205(transcript)|ensembl:ENST00000462686(transcript)|go:"GO:0000309"(nicotinamide-nucleotide adenylyltransferase activity)|go:"GO:0004515"(nicotinate-nucleotide adenylyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0009165"(nucleotide biosynthetic process)|go:"GO:0009435"(NAD biosynthetic process)|go:"GO:0009611"(response to wounding)|go:"GO:0016604"(nuclear body)|go:"GO:0042802"(identical protein binding)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:1902511"(negative regulation of apoptotic DNA fragmentation)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|interpro:IPR004821(Cytidyltransferase-related)|interpro:IPR005248(Probable nicotinate-nucleotide adenylyltransferase)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|mint:Q9HAN9|rcsb pdb:1GZU|rcsb pdb:1KKU|rcsb pdb:1KQN|rcsb pdb:1KQO|rcsb pdb:1KR2|reactome:R-HSA-196807|refseq:XP_016857596.1|dip:DIP-60881N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rogid:KwV9lz04z3ptlVpKu3b534Yekpc9606 rigid:s3ifZ+l90wvENEOPfdOzqDZH6E0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15514 uniprotkb:O75586 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 intact:EBI-394624|uniprotkb:Q6FHQ4|uniprotkb:Q9BTH1|uniprotkb:Q9UHL1|uniprotkb:O15401|uniprotkb:Q53FE3|uniprotkb:Q53HJ3|uniprotkb:B4DU17|uniprotkb:B4E2P0|ensembl:ENSP00000256379 psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:med6_human(display_long)|uniprotkb:ARC33(gene name synonym)|uniprotkb:MED6(gene name)|psi-mi:MED6(display_short)|uniprotkb:Mediator complex subunit 6(gene name synonym)|uniprotkb:Activator-recruited cofactor 33 kDa component(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-28(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482631|imex:IM-26985-343 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N refseq:NP_005457.2|refseq:NP_001271138.1|refseq:NP_001271139.1|refseq:NP_001271140.1|ensembl:ENSG00000133997(gene)|ensembl:ENST00000256379(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR007018(MED6 mediator)|interpro:IPR016820(Mediator complex, subunit 6, metazoa/plant)|interpro:IPR038566|mint:O75586|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31456N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rogid:QYK+2tX/HC1OGGPu3b3S1v/ODR89606 rigid:s3ifZ+l90wvENEOPfdOzqDZH6E0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15514 uniprotkb:Q96HR3 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 intact:EBI-394659|uniprotkb:C6GKU9|intact:EBI-11137618|ensembl:ENSP00000297347 psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:med30_human(display_long)|uniprotkb:TRAP25(gene name synonym)|uniprotkb:MED30(gene name)|psi-mi:MED30(display_short)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)|uniprotkb:TRAP/Mediator complex component TRAP25(gene name synonym)|uniprotkb:THRAP6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482631|imex:IM-26985-343 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N refseq:NP_542382.1|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|mint:Q96HR3|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001269915.1|ensembl:ENSG00000164758(gene)|ensembl:ENST00000297347(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity) - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rogid:dUgR7zxbKAcYqPKb8teHBLgUhWY9606 rigid:s3ifZ+l90wvENEOPfdOzqDZH6E0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15514 uniprotkb:Q15648 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 intact:EBI-394459|uniprotkb:A2RRQ6|uniprotkb:O43810|uniprotkb:O75447|uniprotkb:Q6P9H7|uniprotkb:Q6PK58|uniprotkb:Q9HD39|ensembl:ENSP00000300651 psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:med1_human(display_long)|uniprotkb:TRIP2(gene name synonym)|uniprotkb:MED1(gene name)|psi-mi:MED1(display_short)|uniprotkb:ARC205(gene name synonym)|uniprotkb:DRIP205(gene name synonym)|uniprotkb:TRAP220(gene name synonym)|uniprotkb:Activator-recruited cofactor 205 kDa component(gene name synonym)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-binding protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 220 kDa component(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 2(gene name synonym)|uniprotkb:p53 regulatory protein RB18A(gene name synonym)|uniprotkb:Vitamin D receptor-interacting protein complex component DRIP205(gene name synonym)|uniprotkb:CRSP1(gene name synonym)|uniprotkb:CRSP200(gene name synonym)|uniprotkb:DRIP230(gene name synonym)|uniprotkb:PBP(gene name synonym)|uniprotkb:PPARBP(gene name synonym)|uniprotkb:PPARGBP(gene name synonym)|uniprotkb:RB18A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482631|imex:IM-26985-343 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N refseq:NP_004765.2|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR019680|mint:Q15648|rcsb pdb:1RJK|rcsb pdb:1RK3|rcsb pdb:1RKG|rcsb pdb:1RKH|rcsb pdb:2O4J|rcsb pdb:2O4R|rcsb pdb:2ZFX|rcsb pdb:3A2H|rcsb pdb:3AUN|rcsb pdb:3VJS|rcsb pdb:3VJT|rcsb pdb:3VRT|rcsb pdb:3VRU|rcsb pdb:3VRV|rcsb pdb:3VRW|rcsb pdb:3W0G|rcsb pdb:3W0H|rcsb pdb:3W0I|rcsb pdb:3W0J|rcsb pdb:3W5P|rcsb pdb:3W5Q|rcsb pdb:3W5R|rcsb pdb:3W5T|rcsb pdb:3WT5|rcsb pdb:3WT6|rcsb pdb:3WT7|rcsb pdb:3WTQ|rcsb pdb:4YNK|rcsb pdb:5AWJ|rcsb pdb:5AWK|rcsb pdb:5B41|rcsb pdb:5B5B|rcsb pdb:5GIC|rcsb pdb:5GID|rcsb pdb:5GIE|rcsb pdb:5XPM|rcsb pdb:5XPN|rcsb pdb:5XPO|rcsb pdb:5XPP|rcsb pdb:5XUQ|rcsb pdb:5XZF|rcsb pdb:5XZH|rcsb pdb:5ZWE|rcsb pdb:5ZWF|rcsb pdb:5ZWH|rcsb pdb:5ZWI|rcsb pdb:6D94|rcsb pdb:6JEZ|rcsb pdb:6K5O|rcsb pdb:6ONJ|rcsb pdb:7C7V|rcsb pdb:7C7W|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9707564|reactome:R-HSA-9707616|ensembl:ENSG00000125686(gene)|ensembl:ENST00000300651(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003406"(retinal pigment epithelium development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0050693"(LBD domain binding)|dip:DIP-24212N - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rogid:A4EIAri9zYycSlTA7s6NzbOi9n49606 rigid:s3ifZ+l90wvENEOPfdOzqDZH6E0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15514 uniprotkb:A0JLT2 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 intact:EBI-394430|uniprotkb:Q8IV02|intact:EBI-394763|uniprotkb:Q8IZD1 psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:med19_human(display_long)|uniprotkb:MED19(gene name)|psi-mi:MED19(display_short)|uniprotkb:LCMR1(gene name synonym)|uniprotkb:Lung cancer metastasis-related protein 1(gene name synonym)|uniprotkb:Mediator complex subunit 19(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482631|imex:IM-26985-343 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N refseq:NP_001304007.1|refseq:NP_703151.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR019403|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|mint:A0JLT2|dip:DIP-31467N - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rogid:zcHhU2hQvuTpkFZz/xEKYmjrwOA9606 rigid:s3ifZ+l90wvENEOPfdOzqDZH6E0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15514 uniprotkb:O95402 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 intact:EBI-394392|uniprotkb:A1A4S3|uniprotkb:Q0VGB6|intact:EBI-28974475|ensembl:ENSP00000263390 psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:med26_human(display_long)|uniprotkb:ARC70(gene name synonym)|uniprotkb:MED26(gene name)|psi-mi:MED26(display_short)|uniprotkb:Mediator complex subunit 26(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 7(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP70(gene name synonym)|uniprotkb:Activator-recruited cofactor 70 kDa component(gene name synonym)|uniprotkb:CRSP7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482631|imex:IM-26985-343 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N ensembl:ENSP00000263390|ensembl:ENST00000611692|ensembl:ENSP00000484490|refseq:NP_004822.2|ensembl:ENSG00000105085(gene)|ensembl:ENST00000263390(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR017923|interpro:IPR031416|interpro:IPR031417|interpro:IPR035441|interpro:IPR042376|mint:O95402|rcsb pdb:5ODD|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31464N - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rogid:1kRmQ+QH5uQkKVfjo2Rc2SkAyKc9606 rigid:s3ifZ+l90wvENEOPfdOzqDZH6E0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15514 uniprotkb:Q7KZ85 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 intact:EBI-2515547|ensembl:ENSP00000319104|ensembl:ENSP00000338143|uniprotkb:Q96AH3|uniprotkb:Q7KYW9|uniprotkb:Q6GMQ4|uniprotkb:Q8N526|uniprotkb:Q15737|uniprotkb:Q9BTI2|uniprotkb:Q92775|uniprotkb:Q9BTH9|uniprotkb:Q7LDK4|uniprotkb:A7E2B4 psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:spt6h_human(display_long)|uniprotkb:SUPT6H(gene name)|psi-mi:SUPT6H(display_short)|uniprotkb:KIAA0162(gene name synonym)|uniprotkb:SPT6H(gene name synonym)|uniprotkb:Tat-cotransactivator 2 protein(gene name synonym)|uniprotkb:Histone chaperone suppressor of Ty6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482631|imex:IM-26985-343 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006397"(mRNA processing)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008380"(RNA splicing)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034728"(nucleosome organization)|go:"GO:0035327"|go:"GO:0042393"(histone binding)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045191"(regulation of isotype switching)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0051028"(mRNA transport)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0070827"(obsolete chromatin maintenance)|interpro:IPR000980(SH2 motif)|interpro:IPR003029(S1, RNA binding)|interpro:IPR006641(Resolvase, RNase H-like fold)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR017072(Transcription elongation factor Spt6)|interpro:IPR022967|interpro:IPR023319|interpro:IPR028083|interpro:IPR028088|interpro:IPR028231|interpro:IPR032706|interpro:IPR035018|interpro:IPR035019|interpro:IPR035420|interpro:IPR036860|interpro:IPR037027|interpro:IPR041692|interpro:IPR042066|mint:Q7KZ85|rcsb pdb:6GME|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|interpro:IPR023323|ensembl:ENSG00000109111(gene)|ensembl:ENST00000314616(transcript)|ensembl:ENST00000347486(transcript)|go:"GO:0001825"(blastocyst formation)|refseq:XP_016880467.1|refseq:XP_016880468.1|refseq:XP_016880469.1|refseq:NP_003161.2|refseq:NP_001307684.1|dip:DIP-42615N - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rogid:G1HKe2xEnti5tcZvbH4uqLOwKNg9606 rigid:s3ifZ+l90wvENEOPfdOzqDZH6E0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15514 uniprotkb:Q9H7N4 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 intact:EBI-1222181|uniprotkb:Q7Z5V7|uniprotkb:Q8WVA1|uniprotkb:Q9NR59|ensembl:ENSP00000353769 psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:sfr19_human(display_long)|uniprotkb:SCAF1(gene name)|psi-mi:SCAF1(display_short)|uniprotkb:SRA1(gene name synonym)|uniprotkb:SFRS19(gene name synonym)|uniprotkb:Serine arginine-rich pre-mRNA splicing factor SR-A1(gene name synonym)|uniprotkb:SR-related-CTD-associated factor(gene name synonym)|uniprotkb:SR-related C-terminal domain-associated factor 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482631|imex:IM-26985-343 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N refseq:NP_067051.2|refseq:XP_005259179.1|ensembl:ENSG00000126461(gene)|ensembl:ENST00000360565(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|interpro:IPR042841|mint:Q9H7N4 - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rogid:pF10w7xZFQgiVOiZ/mmPKKArwHE9606 rigid:s3ifZ+l90wvENEOPfdOzqDZH6E0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15514 uniprotkb:O60942 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 intact:EBI-1237132|uniprotkb:O43483|uniprotkb:O60257|uniprotkb:O60351|uniprotkb:Q5TCW8|uniprotkb:Q8WUM8|uniprotkb:E1P513|uniprotkb:E1P514|ensembl:ENSP00000358497 psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:mce1_human(display_long)|uniprotkb:RNGTT(gene name)|psi-mi:RNGTT(display_short)|uniprotkb:CAP1A(gene name synonym)|uniprotkb:HCE(gene name synonym)|uniprotkb:HCAP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482631|imex:IM-26985-343 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N refseq:NP_001273355.1|refseq:NP_001273357.1|refseq:NP_003791.3|dip:DIP-61014N|ensembl:ENSG00000111880(gene)|ensembl:ENST00000369485(transcript)|go:"GO:0004484"(mRNA guanylyltransferase activity)|go:"GO:0004651"(polynucleotide 5'-phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0006396"(RNA processing)|go:"GO:0008192"(RNA guanylyltransferase activity)|go:"GO:0050355"(triphosphatase activity)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR001339(mRNA capping enzyme)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013846(mRNA capping enzyme, C-terminal)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR017074(mRNA capping enzyme, bifunctional)|interpro:IPR020422|interpro:IPR029021|mint:O60942|rcsb pdb:2C46|rcsb pdb:3S24|reactome:R-HSA-167160|reactome:R-HSA-72086|reactome:R-HSA-77075 - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rogid:xiqdXQd75dIqosHNWDCIs1ORyJQ9606 rigid:s3ifZ+l90wvENEOPfdOzqDZH6E0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15514 uniprotkb:Q6P2C8 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 intact:EBI-394603|uniprotkb:Q4F964|uniprotkb:O95401|uniprotkb:Q5VTA4|uniprotkb:Q5VTA5|uniprotkb:Q9BU57|uniprotkb:Q9NYR4|uniprotkb:V9GYV9|ensembl:ENSP00000292035 psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:med27_human(display_long)|uniprotkb:MED27(gene name)|psi-mi:MED27(display_short)|uniprotkb:Mediator complex subunit 27(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 8(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP34(gene name synonym)|uniprotkb:P37 TRAP/SMCC/PC2 subunit(gene name synonym)|uniprotkb:CRSP34(gene name synonym)|uniprotkb:CRSP8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482631|imex:IM-26985-343 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N refseq:NP_001240811.1|refseq:NP_004260.2|refseq:NP_001240810.1|dip:DIP-31465N|ensembl:ENSG00000160563(gene)|ensembl:ENST00000292035(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021627|mint:Q6P2C8|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rogid:V1clNhbtflCzCkC7OnaHGYrmQp89606 rigid:s3ifZ+l90wvENEOPfdOzqDZH6E0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15514 uniprotkb:Q9H204 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 intact:EBI-514199|uniprotkb:Q9BZJ5|ensembl:ENSP00000237380 psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:med28_human(display_long)|uniprotkb:Mediator complex subunit 28(gene name synonym)|uniprotkb:Tumor angiogenesis marker EG-1(gene name synonym)|uniprotkb:Endothelial-derived protein 1(gene name synonym)|uniprotkb:Merlin and Grb2-interacting cytoskeletal protein(gene name synonym)|uniprotkb:MED28(gene name)|psi-mi:MED28(display_short)|uniprotkb:EG1(gene name synonym)|uniprotkb:FKSG20(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482631|imex:IM-26985-343 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N refseq:NP_079481.2|ensembl:ENSG00000118579(gene)|ensembl:ENST00000237380(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0051151"(negative regulation of smooth muscle cell differentiation)|interpro:IPR021640|mint:Q9H204|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rogid:1gt/0vP7vWJ+M1fU+qZPcWGj34U9606 rigid:s3ifZ+l90wvENEOPfdOzqDZH6E0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15514 uniprotkb:O60244 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 intact:EBI-394489|uniprotkb:Q4KMR7|uniprotkb:Q9UNB3|ensembl:ENSP00000323720 psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:med14_human(display_long)|uniprotkb:TRAP170(gene name synonym)|uniprotkb:MED14(gene name)|psi-mi:MED14(display_short)|uniprotkb:ARC150(gene name synonym)|uniprotkb:DRIP150(gene name synonym)|uniprotkb:EXLM1(gene name synonym)|uniprotkb:RGR1(gene name synonym)|uniprotkb:Mediator complex subunit 14(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 2(gene name synonym)|uniprotkb:RGR1 homolog(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP150(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 150 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 170 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 150 kDa component(gene name synonym)|uniprotkb:CRSP2(gene name synonym)|uniprotkb:CXorf4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482631|imex:IM-26985-343 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N refseq:NP_004220.2|ensembl:ENSG00000180182(gene)|ensembl:ENST00000324817(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR013947(Mediator complex, subunit MED14)|mint:O60244|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31460N - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rogid:73RBAnwmB4Lyl/kcsg7NKSUmA4c9606 rigid:s3ifZ+l90wvENEOPfdOzqDZH6E0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15514 uniprotkb:Q96G25 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 intact:EBI-394405|uniprotkb:A9IZ91|uniprotkb:Q96FQ4|uniprotkb:A9IZ92|uniprotkb:Q5JUY8|ensembl:ENSP00000361535 psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:med8_human(display_long)|uniprotkb:MED8(gene name)|psi-mi:MED8(display_short)|uniprotkb:Mediator complex subunit 8(gene name synonym)|uniprotkb:Activator-recruited cofactor 32 kDa component(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482631|imex:IM-26985-343 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N refseq:NP_443109.2|refseq:NP_963836.2|refseq:NP_001001653.1|ensembl:ENSG00000159479(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|mint:Q96G25|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENST00000372457(transcript) - - comment:"author score: 28" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rogid:e/ye7rfa2E1XOPb5vVhI9Nvqmxw9606 rigid:s3ifZ+l90wvENEOPfdOzqDZH6E0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15514 uniprotkb:Q9NVC6 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 intact:EBI-394562|uniprotkb:Q9HA81|uniprotkb:Q9UNP7|uniprotkb:Q9Y2W0|uniprotkb:Q9Y660|uniprotkb:B3KN07|ensembl:ENSP00000251871 psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:med17_human(display_long)|uniprotkb:TRAP80(gene name synonym)|uniprotkb:MED17(gene name)|psi-mi:MED17(display_short)|uniprotkb:ARC77(gene name synonym)|uniprotkb:DRIP80(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 6(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP77(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 80 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 80 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 77 kDa component(gene name synonym)|uniprotkb:CRSP6(gene name synonym)|uniprotkb:DRIP77(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482631|imex:IM-26985-343 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N refseq:NP_004259.3|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|ensembl:ENSG00000042429(gene)|ensembl:ENST00000251871(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019313|mint:Q9NVC6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31451N - - comment:"author score: 29" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rogid:P2hRQOjWEtjw5V+lt7J9TP3VbpU9606 rigid:s3ifZ+l90wvENEOPfdOzqDZH6E0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15514 uniprotkb:Q9H944 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 intact:EBI-394644|uniprotkb:Q9Y429|uniprotkb:O95821|uniprotkb:Q5T8J4|uniprotkb:B4DE08|ensembl:ENSP00000265350 psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:med20_human(display_long)|uniprotkb:TRFP(gene name synonym)|uniprotkb:MED20(gene name)|psi-mi:MED20(display_short)|uniprotkb:Mediator complex subunit 20(gene name synonym)|uniprotkb:TRF-proximal protein homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482631|imex:IM-26985-343 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N refseq:NP_004266.2|refseq:NP_001292384.1|refseq:NP_001292385.1|refseq:NP_001292386.1|go:"GO:0016592"(mediator complex)|interpro:IPR013921(TATA-binding related factor)|mint:Q9H944|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000124641(gene)|ensembl:ENST00000265350(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|dip:DIP-31449N - - comment:"author score: 30" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rogid:MpYOrONH6+0lKIlO6J+Szjzkw2A9606 rigid:s3ifZ+l90wvENEOPfdOzqDZH6E0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15514 uniprotkb:O95104 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 intact:EBI-2854897|uniprotkb:Q6P1M5|uniprotkb:Q8N3I8|uniprotkb:Q9ULP8|uniprotkb:Q0P5W8|uniprotkb:Q9UFM1|uniprotkb:C9JLZ0|ensembl:ENSP00000286835 psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:scaf4_human(display_long)|uniprotkb:SCAF4(gene name)|psi-mi:SCAF4(display_short)|uniprotkb:Splicing factor, arginine/serine-rich 15(gene name synonym)|uniprotkb:SFRS15(gene name synonym)|uniprotkb:KIAA1172(gene name synonym)|uniprotkb:CTD-binding SR-like protein RA4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482631|imex:IM-26985-343 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N refseq:NP_001138916.1|refseq:NP_001138917.1|refseq:NP_065757.1|ensembl:ENSG00000156304(gene)|ensembl:ENST00000286835(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2000805"("negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled")|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034369|interpro:IPR035979|mint:O95104|rcsb pdb:6XKB - - comment:"author score: 34" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rogid:l++VfjjY/kfVHl+bhXTWsyyL4Zc9606 rigid:s3ifZ+l90wvENEOPfdOzqDZH6E0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15514 uniprotkb:Q9NPJ6 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648 psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482631|imex:IM-26985-343 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 - - comment:"author score: 34" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rogid:Bept2Oec50gruA9e4pf+eEUiANM9606 rigid:s3ifZ+l90wvENEOPfdOzqDZH6E0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15514 uniprotkb:Q9BTT4 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 intact:EBI-394354|uniprotkb:C6G491|ensembl:ENSP00000255764 psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:med10_human(display_long)|uniprotkb:MED10(gene name)|psi-mi:MED10(display_short)|uniprotkb:L6(orf name)|uniprotkb:TRG17(orf name)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Transformation-related gene 17 protein(gene name synonym)|uniprotkb:Transformation-related gene 20 protein(gene name synonym)|uniprotkb:TRG20(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482631|imex:IM-26985-343 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N ensembl:ENSG00000133398(gene)|ensembl:ENST00000255764(transcript)|refseq:NP_115662.2|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019145|mint:Q9BTT4|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|go:"GO:0000151"(ubiquitin ligase complex)|dip:DIP-31457N - - comment:"author score: 40" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rogid:LzJW7C8kl2pWmffOjo8S/FNSS9I9606 rigid:s3ifZ+l90wvENEOPfdOzqDZH6E0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15514 uniprotkb:Q13503 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892 psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482631|imex:IM-26985-343 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N - - comment:"author score: 42" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606 rigid:s3ifZ+l90wvENEOPfdOzqDZH6E0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15514 uniprotkb:P61218 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 intact:EBI-395180|uniprotkb:P41584|uniprotkb:Q6IAY3|ensembl:ENSP00000403852 psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:rpab2_human(display_long)|uniprotkb:POLRF(gene name synonym)|uniprotkb:POLR2F(gene name)|psi-mi:POLR2F(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit F(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I, II, and III 14.4 kDa polypeptide(gene name synonym)|uniprotkb:RPABC14.4(gene name synonym)|uniprotkb:RPB6 homolog(gene name synonym)|uniprotkb:RPC15(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482631|imex:IM-26985-343 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N refseq:NP_068809.1|interpro:IPR036161|mint:P61218|rcsb pdb:1QKL|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|ensembl:ENSG00000100142(gene)|ensembl:ENST00000442738(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR006110(RNA polymerase Rpb6)|interpro:IPR006111(DNA-directed RNA polymerase, 14 to 18 kDa subunit)|interpro:IPR012293(RNA polymerase subunit, RPB6/omega)|interpro:IPR020708|interpro:IPR028363|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|dip:DIP-32915N - - comment:"author score: 51" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rogid:ljFKMfBLzZ3qRT27we7Gqdh0jv89606 rigid:s3ifZ+l90wvENEOPfdOzqDZH6E0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15514 uniprotkb:O94762 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 intact:EBI-395321|ensembl:ENSP00000317636|uniprotkb:Q9P1W7|uniprotkb:Q9UNC8|uniprotkb:Q9H0B1|uniprotkb:Q6P4G0 psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:recq5_human(display_long)|uniprotkb:RECQ5(gene name synonym)|uniprotkb:RECQL5(gene name)|psi-mi:RECQL5(display_short)|uniprotkb:RecQ protein-like 5(gene name synonym)|uniprotkb:DNA helicase, RecQ-like type 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482631|imex:IM-26985-343 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N ensembl:ENSG00000108469(gene)|ensembl:ENST00000317905(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006260"(DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0051301"(cell division)|go:"GO:0051304"(chromosome separation)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR010716(RecQ helicase-like 5)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR032284|interpro:IPR001650(DNA/RNA helicase, C-terminal)|refseq:NP_001003715.1|refseq:NP_001003716.1|refseq:NP_004250.4|mint:O94762|rcsb pdb:4BK0|rcsb pdb:5LB3|rcsb pdb:5LB5|rcsb pdb:5LB8|rcsb pdb:5LBA|refseq:XP_016880832.1|refseq:XP_016880833.1|dip:DIP-32964N - - comment:"author score: 75" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rogid:lOMr1rIrRi78aQO2pQod/1V3Ku49606 rigid:s3ifZ+l90wvENEOPfdOzqDZH6E0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15514 uniprotkb:Q8IXW5 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 intact:EBI-395878|uniprotkb:Q49AS7|uniprotkb:Q9H8Y2|ensembl:ENSP00000476948|uniprotkb:C9JKB5 psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:rpap2_human(display_long)|uniprotkb:RPAP2(gene name)|psi-mi:RPAP2(display_short)|uniprotkb:C1orf82(gene name synonym)|uniprotkb:RNA polymerase II-associated protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482631|imex:IM-26985-343 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N refseq:NP_079089.2|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008420"(RNA polymerase II CTD heptapeptide repeat phosphatase activity)|go:"GO:0009301"(snRNA transcription)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0043175"(RNA polymerase core enzyme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR007308(Protein of unknown function DUF408)|interpro:IPR038534|interpro:IPR039693|mint:Q8IXW5|rcsb pdb:7B7U|reactome:R-HSA-6807505|ensembl:ENSG00000122484(gene)|ensembl:ENST00000610020(transcript)|go:"GO:0005634"(nucleus)|dip:DIP-32939N - - comment:"author score: 102" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rogid:niEFEvqkASycxkzfe9TYJuerUuY9606 rigid:s3ifZ+l90wvENEOPfdOzqDZH6E0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15514 uniprotkb:P53803 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 intact:EBI-395357|uniprotkb:Q6IBD4|ensembl:ENSP00000342889 psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:rpab4_human(display_long)|uniprotkb:POLR2K(gene name)|psi-mi:POLR2K(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit K(gene name synonym)|uniprotkb:RPB10alpha(gene name synonym)|uniprotkb:RNA polymerase II 7.0 kDa subunit(gene name synonym)|uniprotkb:ABC10-alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482631|imex:IM-26985-343 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N refseq:NP_005025.1|ensembl:ENSG00000147669(gene)|ensembl:ENST00000353107(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006356"(regulation of transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0008270"(zinc ion binding)|interpro:IPR006591(RNA polymerase Rbp10)|interpro:IPR029040|interpro:IPR039747|mint:P53803|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-72086|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32968N - - comment:"author score: 109" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rogid:dVF/14F1klTHtGh1gfpkGB3YMoU9606 rigid:s3ifZ+l90wvENEOPfdOzqDZH6E0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15514 uniprotkb:Q5VT52 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 intact:EBI-372367|uniprotkb:O75048|uniprotkb:Q5VT53|uniprotkb:Q6MZL4|uniprotkb:Q86XD2|uniprotkb:A8K6N8|uniprotkb:B3KPT1|uniprotkb:Q5VT51|uniprotkb:Q9P0D7|uniprotkb:B4E2Q6|ensembl:ENSP00000358064 psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:rprd2_human(display_long)|uniprotkb:RPRD2(gene name)|psi-mi:RPRD2(display_short)|uniprotkb:KIAA0460(gene name synonym)|uniprotkb:HSPC099(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482631|imex:IM-26985-343 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N refseq:NP_056018.2|ensembl:ENSG00000163125(gene)|ensembl:ENST00000369068(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q5VT52|rcsb pdb:4FLB|reactome:R-HSA-6807505|refseq:NP_001284602.1|refseq:NP_001284603.1|dip:DIP-31155N - - comment:"author score: 118" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rogid:HbkwBBEJ+MNQOjJ2nezU7MJMHYQ9606 rigid:s3ifZ+l90wvENEOPfdOzqDZH6E0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15514 uniprotkb:P0CAP2 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 intact:EBI-9657655|uniprotkb:Q96NF5|uniprotkb:Q6EFN8|uniprotkb:Q6EEV3|uniprotkb:Q9Y3V6|uniprotkb:Q8NC58|uniprotkb:Q96DI5|uniprotkb:Q6EF02|uniprotkb:Q6K050|uniprotkb:Q6K046|uniprotkb:Q6K051|uniprotkb:Q6EF01|uniprotkb:Q6EES2|uniprotkb:Q8NCF3|uniprotkb:Q6EM48|uniprotkb:Q6EF46|uniprotkb:Q6ZQZ3|uniprotkb:Q6EER8|uniprotkb:Q96JB7|uniprotkb:Q6EF00|ensembl:ENSP00000299638 psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:grl1a_human(display_long)|uniprotkb:POLR2M(gene name)|psi-mi:POLR2M(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit M(gene name synonym)|uniprotkb:GRINL1A(gene name synonym)|uniprotkb:Glutamate receptor-like protein 1A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482631|imex:IM-26985-343 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N refseq:NP_001018112.1|refseq:NP_056347.1|dip:DIP-61933N|ensembl:ENSG00000255529(gene)|ensembl:ENST00000299638(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051685"(maintenance of ER location)|interpro:IPR026213|mint:P0CAP2|rcsb pdb:6DRD - - comment:"author score: 146" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rogid:G0QVxeD0uvJTl0VPn+b3pV6zLe89606 rigid:s3ifZ+l90wvENEOPfdOzqDZH6E0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15514 uniprotkb:P24928 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 intact:EBI-295301|uniprotkb:A6NN93|uniprotkb:B9EH88|uniprotkb:Q6NX41|intact:EBI-17957133|intact:EBI-14758660|intact:EBI-13324911|intact:EBI-23311874 psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:rpb1_human(display_long)|uniprotkb:POLR2A(gene name)|psi-mi:POLR2A(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit A(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:POLR2(gene name synonym)|uniprotkb:RNA-directed RNA polymerase II subunit RPB1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482631|imex:IM-26985-343 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N refseq:NP_000928.1|mint:P24928|dip:DIP-29011N|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0019900"(kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:2GHQ|rcsb pdb:2GHT|rcsb pdb:2LTO|rcsb pdb:3D9K|rcsb pdb:3D9L|rcsb pdb:3D9M|rcsb pdb:3D9N|rcsb pdb:3D9O|rcsb pdb:3D9P|rcsb pdb:4JXT|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:5M3H|rcsb pdb:5M3J|rcsb pdb:6DRD|rcsb pdb:6F5P|rcsb pdb:6G0R|rcsb pdb:6IC8|rcsb pdb:6IC9|rcsb pdb:6O9L|rcsb pdb:6Q5Y|rcsb pdb:6XKB|rcsb pdb:6XRE|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095 - - comment:"author score: 162" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rogid:Si2fgh4AMaNtlzvSQhvsuPusX7s9606 rigid:s3ifZ+l90wvENEOPfdOzqDZH6E0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15514 uniprotkb:P30876 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 intact:EBI-394712|uniprotkb:Q8IZ61|uniprotkb:A8K1A8|ensembl:ENSP00000312735|ensembl:ENSP00000370625 psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:rpb2_human(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit B(gene name synonym)|uniprotkb:RNA polymerase II subunit B2(gene name synonym)|uniprotkb:RNA polymerase II subunit 2(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 140 kDa polypeptide(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482631|imex:IM-26985-343 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N refseq:NP_000929.1|refseq:NP_001290197.1|refseq:NP_001290198.1|ensembl:ENSG00000047315(gene)|ensembl:ENST00000314595(transcript)|ensembl:ENST00000381227(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|mint:P30876|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32910N - - comment:"author score: 174" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rogid:YhEjtfLk2QnbRPefOp8ZHX0ejak9606 rigid:s3ifZ+l90wvENEOPfdOzqDZH6E0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15514 uniprotkb:P62875 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 intact:EBI-359527|ensembl:ENSP00000324124|ensembl:ENSP00000432807|uniprotkb:P52436|uniprotkb:Q6FHX3 psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:rpab5_human(display_long)|uniprotkb:POLR2L(gene name)|psi-mi:POLR2L(display_short)|uniprotkb:DNA-directed RNA polymerase III subunit L(gene name synonym)|uniprotkb:RPB10 homolog(gene name synonym)|uniprotkb:RNA polymerase II 7.6 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482631|imex:IM-26985-343 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N ensembl:ENSG00000177700(gene)|ensembl:ENST00000322028(transcript)|ensembl:ENST00000534030(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006356"(regulation of transcription by RNA polymerase I)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR000268(RNA polymerases, N/8 Kd subunits)|interpro:IPR020789|interpro:IPR023580|mint:P62875|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|refseq:NP_066951.1|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-75955|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-203927|dip:DIP-32960N - - comment:"author score: 184" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rogid:uDzgKgHzFTPxFaV1GeUYdYMa4Gk9606 rigid:s3ifZ+l90wvENEOPfdOzqDZH6E0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15514 uniprotkb:P19387 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 intact:EBI-394729|uniprotkb:O15161|ensembl:ENSP00000219252 psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:rpb3_human(display_long)|uniprotkb:POLR2C(gene name)|psi-mi:POLR2C(display_short)|uniprotkb:A-152E5.7(orf name)|uniprotkb:DNA-directed RNA polymerase II subunit C(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 33 kDa polypeptide(gene name synonym)|uniprotkb:RPB31(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482631|imex:IM-26985-343 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N refseq:NP_116558.1|ensembl:ENSG00000102978(gene)|ensembl:ENST00000219252(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001514(DNA-directed RNA polymerase, 30-40 kDa subunit, conserved site)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR036603|interpro:IPR036643|mint:P19387|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32911N - - comment:"author score: 195" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rogid:UXFC+i+QqB2WRgL9OiYSQ66L36c9606 rigid:s3ifZ+l90wvENEOPfdOzqDZH6E0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15514 uniprotkb:P52434 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 intact:EBI-359505|uniprotkb:P53802|uniprotkb:Q969R0|ensembl:ENSP00000392913|uniprotkb:C9J413|uniprotkb:C9JBJ6|uniprotkb:C9JCU7|uniprotkb:C9JUA8 psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:rpab3_human(display_long)|uniprotkb:POLR2H(gene name)|psi-mi:POLR2H(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit H(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I, II, and III 17.1 kDa polypeptide(gene name synonym)|uniprotkb:RPB17(gene name synonym)|uniprotkb:RPB8 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482631|imex:IM-26985-343 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N ensembl:ENSG00000163882(gene)|ensembl:ENST00000456318(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032993"(protein-DNA complex)|interpro:IPR005570(RNA polymerase, Rpb8)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:P52434|rcsb pdb:2F3I|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|refseq:NP_006223.2|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|rcsb pdb:7AE3|reactome:R-HSA-1834949|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-427413|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-203927|refseq:NP_001265627.1|refseq:NP_001265628.1|refseq:NP_001265629.1|refseq:NP_001265644.1|refseq:NP_001265643.1|refseq:XP_006713729.1|refseq:XP_006713730.1|refseq:XP_016862125.1|refseq:XP_016862126.1|dip:DIP-27556N - - comment:"author score: 203" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rogid:h7BRWDi8wRbnw/FcFo25bnlVNkE9606 rigid:s3ifZ+l90wvENEOPfdOzqDZH6E0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15514 uniprotkb:P52435 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 intact:EBI-394753|uniprotkb:O43375|uniprotkb:A5D6V8|ensembl:ENSP00000292614 psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:rpb11_human(display_long)|uniprotkb:POLR2J(gene name)|psi-mi:POLR2J(display_short)|uniprotkb:POLR2J1(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II subunit J-1(gene name synonym)|uniprotkb:RNA polymerase II 13.3 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482631|imex:IM-26985-343 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N refseq:NP_006225.1|ensembl:ENSG00000005075(gene)|ensembl:ENST00000292614(transcript)|go:"GO:0001055"(RNA polymerase II activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0030275"(LRR domain binding)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR008193(DNA-directed RNA polymerase Rpb11, 13-16 kDa subunit, conserved site)|interpro:IPR009025(DNA-directed RNA polymerase, RBP11-like)|interpro:IPR036603|interpro:IPR037685|mint:P52435|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32913N - - comment:"author score: 214" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rogid:jK/DlwFrHHuEJ0Ns3wRoB3icmsA9606 rigid:s3ifZ+l90wvENEOPfdOzqDZH6E0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15514 uniprotkb:P36954 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 intact:EBI-395202|uniprotkb:Q6NW05|uniprotkb:B2R5J2|ensembl:ENSP00000221859 psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:rpb9_human(display_long)|uniprotkb:POLR2I(gene name)|psi-mi:POLR2I(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit I(gene name synonym)|uniprotkb:RNA polymerase II 14.5 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482631|imex:IM-26985-343 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N refseq:NP_006224.1|ensembl:ENSG00000105258(gene)|ensembl:ENST00000221859(transcript)|go:"GO:0001193"(maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034012|mint:P36954|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32917N - - comment:"author score: 224" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rogid:YZUW2UDzj1RhCC46iaX1LvYayNA9606 rigid:s3ifZ+l90wvENEOPfdOzqDZH6E0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15514 uniprotkb:Q96P16 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 intact:EBI-1053506|uniprotkb:Q7Z5G8|uniprotkb:Q96FY9|uniprotkb:Q9NVL4|uniprotkb:A8KA42|uniprotkb:B2RBA3|ensembl:ENSP00000349955|ensembl:ENSP00000381984 psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:rpr1a_human(display_long)|uniprotkb:RPRD1A(gene name)|psi-mi:RPRD1A(display_short)|uniprotkb:p15INK4B-related protein(gene name synonym)|uniprotkb:P15RS(gene name synonym)|uniprotkb:Cyclin-dependent kinase inhibitor 2B-related protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482631|imex:IM-26985-343 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N refseq:XP_011524350.1|refseq:XP_011524351.1|refseq:XP_011524352.1|refseq:NP_060640.2|refseq:NP_001290340.1|refseq:NP_001290341.1|refseq:NP_001290342.1|ensembl:ENSG00000141425(gene)|ensembl:ENST00000357384(transcript)|ensembl:ENST00000399022(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q96P16|rcsb pdb:4JXT|rcsb pdb:4NAC|reactome:R-HSA-6807505|dip:DIP-50901N - - comment:"author score: 225" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rogid:RGCJx8nL9gil6DmtiiFboxeNUSU9606 rigid:s3ifZ+l90wvENEOPfdOzqDZH6E0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15514 uniprotkb:P62487 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 intact:EBI-347928|ensembl:ENSP00000301788|uniprotkb:P52433|uniprotkb:Q2M1Z4|uniprotkb:B2R5C0 psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:rpb7_human(display_long)|uniprotkb:POLR2G(gene name)|psi-mi:POLR2G(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit G(gene name synonym)|uniprotkb:RPB7(gene name synonym)|uniprotkb:RNA polymerase II 19 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482631|imex:IM-26985-343 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N ensembl:ENSG00000168002(gene)|ensembl:ENST00000301788(transcript)|go:"GO:0000291"(nuclear-transcribed mRNA catabolic process, exonucleolytic)|go:"GO:0000932"(P-body)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006915"(apoptotic process)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR003029(S1, RNA binding)|interpro:IPR005576(RNA polymerase Rpb7, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR036898|mint:P62487|rcsb pdb:2C35|rcsb pdb:5IYA|rcsb pdb:5IY6|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|rcsb pdb:5IY7|reactome:R-HSA-167200|reactome:R-HSA-167238|rcsb pdb:5IY8|rcsb pdb:5IY9|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-5601884|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|refseq:NP_002687.1|dip:DIP-32663N - - comment:"author score: 275" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rogid:MtnIweuhSqLFov0c40uOiwv8Eas9606 rigid:s3ifZ+l90wvENEOPfdOzqDZH6E0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:O15212 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-356973|ensembl:ENSP00000363734|ensembl:ENSP00000363735|ensembl:ENSP00000363738|ensembl:ENSP00000372694|ensembl:ENSP00000378563|ensembl:ENSP00000382314|ensembl:ENSP00000382316|ensembl:ENSP00000395462|ensembl:ENSP00000398171|ensembl:ENSP00000400152|ensembl:ENSP00000402212|ensembl:ENSP00000402553|ensembl:ENSP00000403771|ensembl:ENSP00000404773|ensembl:ENSP00000412319|ensembl:ENSP00000415678|ensembl:ENSP00000447540|ensembl:ENSP00000448607|ensembl:ENSP00000448784|ensembl:ENSP00000449925 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:pfd6_human(display_long)|uniprotkb:PFDN6(gene name)|psi-mi:PFDN6(display_short)|uniprotkb:HKE2(gene name synonym)|uniprotkb:PFD6(gene name synonym)|uniprotkb:Protein Ke2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_001172110.1|refseq:NP_055075.1|refseq:NP_001252524.1|refseq:NP_001252525.1|dip:DIP-50304N|ensembl:ENSG00000204220(gene)|ensembl:ENSG00000206283(gene)|ensembl:ENSG00000224782(gene)|ensembl:ENSG00000235692(gene)|ensembl:ENSG00000237335(gene)|ensembl:ENST00000374606(transcript)|ensembl:ENST00000374607(transcript)|ensembl:ENST00000374610(transcript)|ensembl:ENST00000383207(transcript)|ensembl:ENST00000395131(transcript)|ensembl:ENST00000399383(transcript)|ensembl:ENST00000399385(transcript)|ensembl:ENST00000412289(transcript)|ensembl:ENST00000425878(transcript)|ensembl:ENST00000431830(transcript)|ensembl:ENST00000432391(transcript)|ensembl:ENST00000442285(transcript)|ensembl:ENST00000445559(transcript)|ensembl:ENST00000448594(transcript)|ensembl:ENST00000451970(transcript)|ensembl:ENST00000452658(transcript)|ensembl:ENST00000547641(transcript)|ensembl:ENST00000547952(transcript)|ensembl:ENST00000548040(transcript)|ensembl:ENST00000552711(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|mint:O15212|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957 - - crc64:8F138EAAE512A312|comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:t7Z68vuvmprxLIGDh4JhqCGvX+A9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:Q7KZ85 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-2515547|ensembl:ENSP00000319104|ensembl:ENSP00000338143|uniprotkb:Q96AH3|uniprotkb:Q7KYW9|uniprotkb:Q6GMQ4|uniprotkb:Q8N526|uniprotkb:Q15737|uniprotkb:Q9BTI2|uniprotkb:Q92775|uniprotkb:Q9BTH9|uniprotkb:Q7LDK4|uniprotkb:A7E2B4 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:spt6h_human(display_long)|uniprotkb:SUPT6H(gene name)|psi-mi:SUPT6H(display_short)|uniprotkb:KIAA0162(gene name synonym)|uniprotkb:SPT6H(gene name synonym)|uniprotkb:Tat-cotransactivator 2 protein(gene name synonym)|uniprotkb:Histone chaperone suppressor of Ty6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006397"(mRNA processing)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008380"(RNA splicing)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034728"(nucleosome organization)|go:"GO:0035327"|go:"GO:0042393"(histone binding)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045191"(regulation of isotype switching)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0051028"(mRNA transport)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0070827"(obsolete chromatin maintenance)|interpro:IPR000980(SH2 motif)|interpro:IPR003029(S1, RNA binding)|interpro:IPR006641(Resolvase, RNase H-like fold)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR017072(Transcription elongation factor Spt6)|interpro:IPR022967|interpro:IPR023319|interpro:IPR028083|interpro:IPR028088|interpro:IPR028231|interpro:IPR032706|interpro:IPR035018|interpro:IPR035019|interpro:IPR035420|interpro:IPR036860|interpro:IPR037027|interpro:IPR041692|interpro:IPR042066|mint:Q7KZ85|rcsb pdb:6GME|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|interpro:IPR023323|ensembl:ENSG00000109111(gene)|ensembl:ENST00000314616(transcript)|ensembl:ENST00000347486(transcript)|go:"GO:0001825"(blastocyst formation)|refseq:XP_016880467.1|refseq:XP_016880468.1|refseq:XP_016880469.1|refseq:NP_003161.2|refseq:NP_001307684.1|dip:DIP-42615N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:G1HKe2xEnti5tcZvbH4uqLOwKNg9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:Q9H7N4 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-1222181|uniprotkb:Q7Z5V7|uniprotkb:Q8WVA1|uniprotkb:Q9NR59|ensembl:ENSP00000353769 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:sfr19_human(display_long)|uniprotkb:SCAF1(gene name)|psi-mi:SCAF1(display_short)|uniprotkb:SRA1(gene name synonym)|uniprotkb:SFRS19(gene name synonym)|uniprotkb:Serine arginine-rich pre-mRNA splicing factor SR-A1(gene name synonym)|uniprotkb:SR-related-CTD-associated factor(gene name synonym)|uniprotkb:SR-related C-terminal domain-associated factor 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_067051.2|refseq:XP_005259179.1|ensembl:ENSG00000126461(gene)|ensembl:ENST00000360565(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|interpro:IPR042841|mint:Q9H7N4 - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:pF10w7xZFQgiVOiZ/mmPKKArwHE9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:Q9HCN4 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-745137|uniprotkb:O76004|uniprotkb:B4DQJ5|uniprotkb:B4DXU4|uniprotkb:B4DQM4|ensembl:ENSP00000476446|uniprotkb:B5MBZ5 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:gpn1_human(display_long)|uniprotkb:XAB1(gene name synonym)|uniprotkb:XPA-binding protein 1(gene name synonym)|uniprotkb:MBD2-interacting protein(gene name synonym)|uniprotkb:GPN1(gene name)|psi-mi:GPN1(display_short)|uniprotkb:MBDIN(gene name synonym)|uniprotkb:HUSSY-23(orf name)|uniprotkb:RNAPII-associated protein 4(gene name synonym)|uniprotkb:RPAP4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_001138519.1|refseq:NP_001138520.1|refseq:NP_001138521.1|refseq:NP_009197.2|ensembl:ENSG00000198522(gene)|ensembl:ENST00000610189(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004130(Protein of unknown function, ATP binding)|interpro:IPR027417|interpro:IPR030230|mint:Q9HCN4 - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:QZOTFh9d1hOcoG1DxAueYEwbOpc9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:O95104 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-2854897|uniprotkb:Q6P1M5|uniprotkb:Q8N3I8|uniprotkb:Q9ULP8|uniprotkb:Q0P5W8|uniprotkb:Q9UFM1|uniprotkb:C9JLZ0|ensembl:ENSP00000286835 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:scaf4_human(display_long)|uniprotkb:SCAF4(gene name)|psi-mi:SCAF4(display_short)|uniprotkb:Splicing factor, arginine/serine-rich 15(gene name synonym)|uniprotkb:SFRS15(gene name synonym)|uniprotkb:KIAA1172(gene name synonym)|uniprotkb:CTD-binding SR-like protein RA4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_001138916.1|refseq:NP_001138917.1|refseq:NP_065757.1|ensembl:ENSG00000156304(gene)|ensembl:ENST00000286835(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2000805"("negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled")|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034369|interpro:IPR035979|mint:O95104|rcsb pdb:6XKB - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:l++VfjjY/kfVHl+bhXTWsyyL4Zc9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:Q9Y2Y1 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-11023785|ensembl:ENSP00000293860|uniprotkb:Q96S35|uniprotkb:Q1W6H4 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:rpc10_human(display_long)|uniprotkb:POLR3K(gene name)|psi-mi:POLR3K(display_short)|uniprotkb:DNA-directed RNA polymerase III subunit K(gene name synonym)|uniprotkb:RNA polymerase III 12.5 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase III subunit C11(gene name synonym)|uniprotkb:RPC11(gene name synonym)|uniprotkb:My010(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N ensembl:ENSG00000161980(gene)|ensembl:ENST00000293860(transcript)|go:"GO:0003676"(nucleic acid binding)|refseq:NP_057394.3|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0006386"(termination of RNA polymerase III transcription)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042779"(tRNA 3'-trailer cleavage)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034014|mint:Q9Y2Y1|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|reactome:R-HSA-1834949|reactome:R-HSA-73780|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071 - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:26KXQBPLU2oVOA1DSPeu4y5LjLM9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:Q9NUG6 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-307050|uniprotkb:Q96GP3|uniprotkb:Q9BUW8|ensembl:ENSP00000202017|uniprotkb:B2R511 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:pdrg1_human(display_long)|uniprotkb:PDRG1(gene name)|psi-mi:PDRG1(display_short)|uniprotkb:C20orf126(gene name synonym)|uniprotkb:PDRG(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N ensembl:ENSG00000088356(gene)|ensembl:ENST00000202017(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR030482|mint:Q9NUG6|refseq:NP_110442.1|dip:DIP-27568N - - comment:"author score: 37" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:Q6qLyEyyEFBqxYhfx2lYg05nixQ9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:P61218 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-395180|uniprotkb:P41584|uniprotkb:Q6IAY3|ensembl:ENSP00000403852 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:rpab2_human(display_long)|uniprotkb:POLRF(gene name synonym)|uniprotkb:POLR2F(gene name)|psi-mi:POLR2F(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit F(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I, II, and III 14.4 kDa polypeptide(gene name synonym)|uniprotkb:RPABC14.4(gene name synonym)|uniprotkb:RPB6 homolog(gene name synonym)|uniprotkb:RPC15(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_068809.1|interpro:IPR036161|mint:P61218|rcsb pdb:1QKL|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|ensembl:ENSG00000100142(gene)|ensembl:ENST00000442738(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR006110(RNA polymerase Rpb6)|interpro:IPR006111(DNA-directed RNA polymerase, 14 to 18 kDa subunit)|interpro:IPR012293(RNA polymerase subunit, RPB6/omega)|interpro:IPR020708|interpro:IPR028363|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|dip:DIP-32915N - - comment:"author score: 39" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:ljFKMfBLzZ3qRT27we7Gqdh0jv89606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:Q9UHV9 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-359873|uniprotkb:Q9P0P7|uniprotkb:Q9UN05|ensembl:ENSP00000356989 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:pfd2_human(display_long)|uniprotkb:HSPC231(orf name)|uniprotkb:PFDN2(gene name)|psi-mi:PFDN2(display_short)|uniprotkb:PFD2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_036526.2|refseq:XP_011507926.1|ensembl:ENSG00000143256(gene)|ensembl:ENST00000368010(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|interpro:IPR027235|mint:Q9UHV9|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957|dip:DIP-27557N - - comment:"author score: 40" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:rgr14h3vGyzHxHoNJtlHBQkvhUE9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:Q9UBK9 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-357355|ensembl:ENSP00000327797|uniprotkb:B2R561|uniprotkb:Q5JZG3|uniprotkb:Q9Y6E5|uniprotkb:A0A0C4DFR8 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:uxt_human(display_long)|uniprotkb:UXT(gene name)|psi-mi:UXT(display_short)|uniprotkb:HSPC024(orf name)|uniprotkb:Ubiquitously expressed transcript protein(gene name synonym)|uniprotkb:Androgen receptor trapped clone 27 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N ensembl:ENSG00000126756(gene)|ensembl:ENST00000333119(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000785"(chromatin)|go:"GO:0000922"(spindle pole)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048487"(beta-tubulin binding)|interpro:IPR003994(Prefoldin related, ubiquitously expressed transcript)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|mint:Q9UBK9|reactome:R-HSA-8953750|go:"GO:0003714"(transcription corepressor activity)|refseq:NP_004173.1|refseq:NP_705582.1 - - comment:"author score: 40" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:XhE14Q7CfwVXxJ4fTiRQTm3Idvk9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:O15446 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-359424|ensembl:ENSP00000310966|uniprotkb:Q32N11|uniprotkb:Q7Z5U2|uniprotkb:Q9UPF6 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:rpa34_human(display_long)|uniprotkb:RNA polymerase I-associated factor PAF49(gene name synonym)|uniprotkb:POLR1G(gene name)|psi-mi:POLR1G(display_short)|uniprotkb:A34.5(gene name synonym)|uniprotkb:ASE1(gene name synonym)|uniprotkb:Antisense to ERCC-1 protein(gene name synonym)|uniprotkb:CAST(gene name synonym)|uniprotkb:CD3-epsilon-associated protein(gene name synonym)|uniprotkb:CD3EAP(gene name synonym)|uniprotkb:DNA-directed RNA polymerase I subunit G(gene name synonym)|uniprotkb:PAF49(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N go:"GO:0001650"(fibrillar center)|ensembl:ENSG00000117877(gene)|ensembl:ENST00000309424(transcript)|go:"GO:0000120"(RNA polymerase I transcription regulator complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0009303"(rRNA transcription)|interpro:IPR013240(RNA polymerase I, subunit RPA34.5, fungi)|mint:O15446|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73863|refseq:NP_036231.1|refseq:NP_001284519.1|dip:DIP-27616N - - comment:"author score: 40" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:SRxVaX6wEST5kHqhdnE0j24EeSo9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:Q9GZS1 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-359458|uniprotkb:Q5VZT3|uniprotkb:Q8NBA9|uniprotkb:Q96L20|ensembl:ENSP00000367029|intact:EBI-21026140 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:rpa49_human(display_long)|uniprotkb:POLR1E(gene name)|psi-mi:POLR1E(display_short)|uniprotkb:PAF53(gene name synonym)|uniprotkb:PRAF1(gene name synonym)|uniprotkb:DNA-directed RNA polymerase I subunit E(gene name synonym)|uniprotkb:RNA polymerase I-associated factor 1(gene name synonym)|uniprotkb:RNA polymerase I-associated factor 53(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_001269695.1|refseq:NP_071935.1|ensembl:ENSG00000137054(gene)|ensembl:ENST00000377798(transcript)|go:"GO:0001179"(RNA polymerase I general transcription initiation factor binding)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0042790"(nucleolar large rRNA transcription by RNA polymerase I)|interpro:IPR009668(RNA polymerase I associated factor, A49-like)|mint:Q9GZS1|reactome:R-HSA-5250924|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73863|reactome:R-HSA-427413|refseq:XP_005251604.1|dip:DIP-27546N - - comment:"author score: 46" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:3cidLGlybOTCIJGQ6xweDrvBBYM9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:O75575 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-2654687|uniprotkb:Q8IXL4|uniprotkb:Q3KRA3|uniprotkb:A8MW23|uniprotkb:B2R4H4|intact:EBI-2855843|uniprotkb:Q5HYF1|uniprotkb:B4E198|intact:EBI-28977752|ensembl:ENSP00000378736|uniprotkb:A8MUZ4 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:rpc9_human(display_long)|uniprotkb:Calcitonin gene-related peptide-receptor component protein(gene name synonym)|uniprotkb:CRCP(gene name)|psi-mi:CRCP(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_001035738.1|ensembl:ENST00000338592|ensembl:ENSP00000340044|ensembl:ENSP00000378736|ensembl:ENST00000398684|ensembl:ENSP00000381674|ensembl:ENST00000431089|ensembl:ENSP00000388653|refseq:NP_001035737.1|refseq:NP_055293.1|refseq:NP_001135886.1|ensembl:ENSG00000241258(gene)|ensembl:ENST00000395326(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001635"(calcitonin gene-related peptide receptor activity)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0006384"(transcription initiation from RNA polymerase III promoter)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0009360"(DNA polymerase III complex)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|interpro:IPR038846|mint:O75575|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|reactome:R-HSA-1834949|reactome:R-HSA-73780|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071 - - comment:"author score: 47" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:Xrb72g8eT2zV3NAFFyJXEBrloro9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:Q9NWA0 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-394653|ensembl:ENSP00000268711 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:med9_human(display_long)|uniprotkb:MED9(gene name)|psi-mi:MED9(display_short)|uniprotkb:Mediator complex subunit 9(gene name synonym)|uniprotkb:MED25(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_060489.1|ensembl:ENSG00000141026(gene)|ensembl:ENST00000268711(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|interpro:IPR011425(RNA polymerase II transcription mediator)|interpro:IPR037212|interpro:IPR039242|mint:Q9NWA0|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 - - comment:"author score: 49" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:VSYpA1Aqh2FEaZIEF/6iCIpoPEc9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:O75586 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-394624|uniprotkb:Q6FHQ4|uniprotkb:Q9BTH1|uniprotkb:Q9UHL1|uniprotkb:O15401|uniprotkb:Q53FE3|uniprotkb:Q53HJ3|uniprotkb:B4DU17|uniprotkb:B4E2P0|ensembl:ENSP00000256379 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:med6_human(display_long)|uniprotkb:ARC33(gene name synonym)|uniprotkb:MED6(gene name)|psi-mi:MED6(display_short)|uniprotkb:Mediator complex subunit 6(gene name synonym)|uniprotkb:Activator-recruited cofactor 33 kDa component(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-28(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_005457.2|refseq:NP_001271138.1|refseq:NP_001271139.1|refseq:NP_001271140.1|ensembl:ENSG00000133997(gene)|ensembl:ENST00000256379(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR007018(MED6 mediator)|interpro:IPR016820(Mediator complex, subunit 6, metazoa/plant)|interpro:IPR038566|mint:O75586|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31456N - - comment:"author score: 57" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:QYK+2tX/HC1OGGPu3b3S1v/ODR89606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:Q9NWS0 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-357318|intact:EBI-748162|uniprotkb:B4DGN7|uniprotkb:B4E2X7|uniprotkb:Q9BVL0|ensembl:ENSP00000262265|ensembl:ENSP00000470445 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:pihd1_human(display_long)|uniprotkb:PIH1D1(gene name)|psi-mi:PIH1D1(display_short)|uniprotkb:NOP17(gene name synonym)|uniprotkb:Nucleolar protein 17 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_060386.1|ensembl:ENSG00000104872(gene)|ensembl:ENST00000262265(transcript)|ensembl:ENST00000596049(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0001164"(RNA polymerase I core promoter sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006364"(rRNA processing)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0042393"(histone binding)|go:"GO:0048254"(snoRNA localization)|go:"GO:0051117"(ATPase binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0070761"(pre-snoRNP complex)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:0097255"(R2TP complex)|go:"GO:1900110"(negative regulation of histone H3-K9 dimethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|go:"GO:2000619"(negative regulation of histone H4-K16 acetylation)|go:"GO:2001268"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR012981(Nop17p)|interpro:IPR041442|mint:Q9NWS0|rcsb pdb:4PSF|rcsb pdb:4PSI|rcsb pdb:6GXZ|rcsb pdb:7AVC - - comment:"author score: 60" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:lugKS0BlzZYpMZn/7LFHODnFk0Q9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:Q9P1U0 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-355434|ensembl:ENSP00000407364|ensembl:ENSP00000407715|ensembl:ENSP00000410127|ensembl:ENSP00000410530|ensembl:ENSP00000410954|ensembl:ENSP00000412369|ensembl:ENSP00000413265|ensembl:ENSP00000414110|ensembl:ENSP00000414720|ensembl:ENSP00000416599|ensembl:ENSP00000405636|ensembl:ENSP00000331111|ensembl:ENSP00000352333|ensembl:ENSP00000365978|ensembl:ENSP00000365981|ensembl:ENSP00000373108|ensembl:ENSP00000383500|ensembl:ENSP00000383501|ensembl:ENSP00000383503|ensembl:ENSP00000387914|ensembl:ENSP00000391809|ensembl:ENSP00000393236|ensembl:ENSP00000394779|ensembl:ENSP00000395065|ensembl:ENSP00000395397|ensembl:ENSP00000396661|ensembl:ENSP00000396922|ensembl:ENSP00000397636|ensembl:ENSP00000399302|ensembl:ENSP00000399966|ensembl:ENSP00000402198|ensembl:ENSP00000405264 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:rpa12_human(display_long)|uniprotkb:POLR1H(gene name)|psi-mi:POLR1H(display_short)|uniprotkb:DNA-directed RNA polymerase I subunit H(gene name synonym)|uniprotkb:RPA12(gene name synonym)|uniprotkb:ZNRD1(gene name synonym)|uniprotkb:Zinc ribbon domain-containing protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_055411.1|refseq:NP_740753.1|refseq:NP_001265714.1|refseq:NP_001265715.1|ensembl:ENST00000332435(transcript)|ensembl:ENST00000359374(transcript)|ensembl:ENST00000376782(transcript)|ensembl:ENST00000376785(transcript)|ensembl:ENST00000383613(transcript)|ensembl:ENST00000400659(transcript)|ensembl:ENST00000400660(transcript)|ensembl:ENST00000400662(transcript)|ensembl:ENST00000412396(transcript)|ensembl:ENST00000417275(transcript)|ensembl:ENST00000417738(transcript)|ensembl:ENST00000420100(transcript)|ensembl:ENST00000428913(transcript)|ensembl:ENST00000429558(transcript)|ensembl:ENST00000431032(transcript)|ensembl:ENST00000431416(transcript)|ensembl:ENST00000432227(transcript)|ensembl:ENST00000432545(transcript)|ensembl:ENST00000432904(transcript)|ensembl:ENST00000433264(transcript)|ensembl:ENST00000437373(transcript)|ensembl:ENST00000437507(transcript)|ensembl:ENST00000441251(transcript)|ensembl:ENST00000442585(transcript)|ensembl:ENST00000443142(transcript)|ensembl:ENST00000443494(transcript)|ensembl:ENST00000444027(transcript)|ensembl:ENST00000444794(transcript)|ensembl:ENST00000446493(transcript)|ensembl:ENST00000451875(transcript)|ensembl:ENST00000455948(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006363"(termination of RNA polymerase I transcription)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034004|mint:Q9P1U0|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73863|ensembl:ENST00000453694(transcript)|ensembl:ENSG00000066379(gene)|ensembl:ENSG00000206502(gene)|ensembl:ENSG00000224859(gene)|ensembl:ENSG00000233795(gene)|ensembl:ENSG00000235176(gene)|ensembl:ENSG00000235443(gene)|ensembl:ENSG00000236808(gene)|ensembl:ENSG00000236949(gene) - - comment:"author score: 60" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:zWLcgopYhtpCPeyhS887IK1ZhNw9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:Q9NW08 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-2515106|uniprotkb:A8K6H0|uniprotkb:Q9NW59|uniprotkb:B3KV73|uniprotkb:F5H1E6|ensembl:ENSP00000228347 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:rpc2_human(display_long)|uniprotkb:POLR3B(gene name)|psi-mi:POLR3B(display_short)|uniprotkb:DNA-directed RNA polymerase III subunit B(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III 127.6 kDa polypeptide(gene name synonym)|uniprotkb:C128(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_060552.4|refseq:NP_001154180.1|ensembl:ENSG00000013503(gene)|ensembl:ENST00000228347(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|mint:Q9NW08|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|reactome:R-HSA-1834949|reactome:R-HSA-73780|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071 - - comment:"author score: 60" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:wHQRBDeUbMtfpXmUd/LkiE6GNaM9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:A0JLT2 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-394430|uniprotkb:Q8IV02|intact:EBI-394763|uniprotkb:Q8IZD1 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:med19_human(display_long)|uniprotkb:MED19(gene name)|psi-mi:MED19(display_short)|uniprotkb:LCMR1(gene name synonym)|uniprotkb:Lung cancer metastasis-related protein 1(gene name synonym)|uniprotkb:Mediator complex subunit 19(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_001304007.1|refseq:NP_703151.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR019403|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|mint:A0JLT2|dip:DIP-31467N - - comment:"author score: 61" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:zcHhU2hQvuTpkFZz/xEKYmjrwOA9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:Q6P2C8 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-394603|uniprotkb:Q4F964|uniprotkb:O95401|uniprotkb:Q5VTA4|uniprotkb:Q5VTA5|uniprotkb:Q9BU57|uniprotkb:Q9NYR4|uniprotkb:V9GYV9|ensembl:ENSP00000292035 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:med27_human(display_long)|uniprotkb:MED27(gene name)|psi-mi:MED27(display_short)|uniprotkb:Mediator complex subunit 27(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 8(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP34(gene name synonym)|uniprotkb:P37 TRAP/SMCC/PC2 subunit(gene name synonym)|uniprotkb:CRSP34(gene name synonym)|uniprotkb:CRSP8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_001240811.1|refseq:NP_004260.2|refseq:NP_001240810.1|dip:DIP-31465N|ensembl:ENSG00000160563(gene)|ensembl:ENST00000292035(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021627|mint:Q6P2C8|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 - - comment:"author score: 61" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:V1clNhbtflCzCkC7OnaHGYrmQp89606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:Q9NVC6 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-394562|uniprotkb:Q9HA81|uniprotkb:Q9UNP7|uniprotkb:Q9Y2W0|uniprotkb:Q9Y660|uniprotkb:B3KN07|ensembl:ENSP00000251871 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:med17_human(display_long)|uniprotkb:TRAP80(gene name synonym)|uniprotkb:MED17(gene name)|psi-mi:MED17(display_short)|uniprotkb:ARC77(gene name synonym)|uniprotkb:DRIP80(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 6(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP77(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 80 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 80 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 77 kDa component(gene name synonym)|uniprotkb:CRSP6(gene name synonym)|uniprotkb:DRIP77(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_004259.3|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|ensembl:ENSG00000042429(gene)|ensembl:ENST00000251871(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019313|mint:Q9NVC6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31451N - - comment:"author score: 62" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:P2hRQOjWEtjw5V+lt7J9TP3VbpU9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:O43513 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-394632|ensembl:ENSP00000286317|ensembl:ENSP00000401046 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:med7_human(display_long)|uniprotkb:MED7(gene name)|psi-mi:MED7(display_short)|uniprotkb:CRSP9(gene name synonym)|uniprotkb:ARC34(gene name synonym)|uniprotkb:Mediator complex subunit 7(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 9(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP33(gene name synonym)|uniprotkb:RNA polymerase transcriptional regulation mediator subunit 7 homolog(gene name synonym)|uniprotkb:Activator-recruited cofactor 34 kDa component(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_001094286.1|refseq:NP_004261.1|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000155868(gene)|ensembl:ENST00000286317(transcript)|ensembl:ENST00000420343(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR009244(MED7)|interpro:IPR037212|mint:O43513|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM - - comment:"author score: 63" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:K6K10aETITT6OIwedZj5qvG2OmI9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:P53803 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-395357|uniprotkb:Q6IBD4|ensembl:ENSP00000342889 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:rpab4_human(display_long)|uniprotkb:POLR2K(gene name)|psi-mi:POLR2K(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit K(gene name synonym)|uniprotkb:RPB10alpha(gene name synonym)|uniprotkb:RNA polymerase II 7.0 kDa subunit(gene name synonym)|uniprotkb:ABC10-alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_005025.1|ensembl:ENSG00000147669(gene)|ensembl:ENST00000353107(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006356"(regulation of transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0008270"(zinc ion binding)|interpro:IPR006591(RNA polymerase Rbp10)|interpro:IPR029040|interpro:IPR039747|mint:P53803|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-72086|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32968N - - comment:"author score: 63" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:dVF/14F1klTHtGh1gfpkGB3YMoU9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:O95402 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-394392|uniprotkb:A1A4S3|uniprotkb:Q0VGB6|intact:EBI-28974475|ensembl:ENSP00000263390 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:med26_human(display_long)|uniprotkb:ARC70(gene name synonym)|uniprotkb:MED26(gene name)|psi-mi:MED26(display_short)|uniprotkb:Mediator complex subunit 26(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 7(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP70(gene name synonym)|uniprotkb:Activator-recruited cofactor 70 kDa component(gene name synonym)|uniprotkb:CRSP7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N ensembl:ENSP00000263390|ensembl:ENST00000611692|ensembl:ENSP00000484490|refseq:NP_004822.2|ensembl:ENSG00000105085(gene)|ensembl:ENST00000263390(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR017923|interpro:IPR031416|interpro:IPR031417|interpro:IPR035441|interpro:IPR042376|mint:O95402|rcsb pdb:5ODD|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31464N - - comment:"author score: 65" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:1kRmQ+QH5uQkKVfjo2Rc2SkAyKc9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:O60244 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-394489|uniprotkb:Q4KMR7|uniprotkb:Q9UNB3|ensembl:ENSP00000323720 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:med14_human(display_long)|uniprotkb:TRAP170(gene name synonym)|uniprotkb:MED14(gene name)|psi-mi:MED14(display_short)|uniprotkb:ARC150(gene name synonym)|uniprotkb:DRIP150(gene name synonym)|uniprotkb:EXLM1(gene name synonym)|uniprotkb:RGR1(gene name synonym)|uniprotkb:Mediator complex subunit 14(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 2(gene name synonym)|uniprotkb:RGR1 homolog(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP150(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 150 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 170 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 150 kDa component(gene name synonym)|uniprotkb:CRSP2(gene name synonym)|uniprotkb:CXorf4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_004220.2|ensembl:ENSG00000180182(gene)|ensembl:ENST00000324817(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR013947(Mediator complex, subunit MED14)|mint:O60244|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31460N - - comment:"author score: 65" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:73RBAnwmB4Lyl/kcsg7NKSUmA4c9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:Q15648 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-394459|uniprotkb:A2RRQ6|uniprotkb:O43810|uniprotkb:O75447|uniprotkb:Q6P9H7|uniprotkb:Q6PK58|uniprotkb:Q9HD39|ensembl:ENSP00000300651 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:med1_human(display_long)|uniprotkb:TRIP2(gene name synonym)|uniprotkb:MED1(gene name)|psi-mi:MED1(display_short)|uniprotkb:ARC205(gene name synonym)|uniprotkb:DRIP205(gene name synonym)|uniprotkb:TRAP220(gene name synonym)|uniprotkb:Activator-recruited cofactor 205 kDa component(gene name synonym)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-binding protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 220 kDa component(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 2(gene name synonym)|uniprotkb:p53 regulatory protein RB18A(gene name synonym)|uniprotkb:Vitamin D receptor-interacting protein complex component DRIP205(gene name synonym)|uniprotkb:CRSP1(gene name synonym)|uniprotkb:CRSP200(gene name synonym)|uniprotkb:DRIP230(gene name synonym)|uniprotkb:PBP(gene name synonym)|uniprotkb:PPARBP(gene name synonym)|uniprotkb:PPARGBP(gene name synonym)|uniprotkb:RB18A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_004765.2|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR019680|mint:Q15648|rcsb pdb:1RJK|rcsb pdb:1RK3|rcsb pdb:1RKG|rcsb pdb:1RKH|rcsb pdb:2O4J|rcsb pdb:2O4R|rcsb pdb:2ZFX|rcsb pdb:3A2H|rcsb pdb:3AUN|rcsb pdb:3VJS|rcsb pdb:3VJT|rcsb pdb:3VRT|rcsb pdb:3VRU|rcsb pdb:3VRV|rcsb pdb:3VRW|rcsb pdb:3W0G|rcsb pdb:3W0H|rcsb pdb:3W0I|rcsb pdb:3W0J|rcsb pdb:3W5P|rcsb pdb:3W5Q|rcsb pdb:3W5R|rcsb pdb:3W5T|rcsb pdb:3WT5|rcsb pdb:3WT6|rcsb pdb:3WT7|rcsb pdb:3WTQ|rcsb pdb:4YNK|rcsb pdb:5AWJ|rcsb pdb:5AWK|rcsb pdb:5B41|rcsb pdb:5B5B|rcsb pdb:5GIC|rcsb pdb:5GID|rcsb pdb:5GIE|rcsb pdb:5XPM|rcsb pdb:5XPN|rcsb pdb:5XPO|rcsb pdb:5XPP|rcsb pdb:5XUQ|rcsb pdb:5XZF|rcsb pdb:5XZH|rcsb pdb:5ZWE|rcsb pdb:5ZWF|rcsb pdb:5ZWH|rcsb pdb:5ZWI|rcsb pdb:6D94|rcsb pdb:6JEZ|rcsb pdb:6K5O|rcsb pdb:6ONJ|rcsb pdb:7C7V|rcsb pdb:7C7W|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9707564|reactome:R-HSA-9707616|ensembl:ENSG00000125686(gene)|ensembl:ENST00000300651(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003406"(retinal pigment epithelium development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0050693"(LBD domain binding)|dip:DIP-24212N - - comment:"author score: 65" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:A4EIAri9zYycSlTA7s6NzbOi9n49606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:Q9H944 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-394644|uniprotkb:Q9Y429|uniprotkb:O95821|uniprotkb:Q5T8J4|uniprotkb:B4DE08|ensembl:ENSP00000265350 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:med20_human(display_long)|uniprotkb:TRFP(gene name synonym)|uniprotkb:MED20(gene name)|psi-mi:MED20(display_short)|uniprotkb:Mediator complex subunit 20(gene name synonym)|uniprotkb:TRF-proximal protein homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_004266.2|refseq:NP_001292384.1|refseq:NP_001292385.1|refseq:NP_001292386.1|go:"GO:0016592"(mediator complex)|interpro:IPR013921(TATA-binding related factor)|mint:Q9H944|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000124641(gene)|ensembl:ENST00000265350(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|dip:DIP-31449N - - comment:"author score: 65" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:MpYOrONH6+0lKIlO6J+Szjzkw2A9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:Q96G25 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-394405|uniprotkb:A9IZ91|uniprotkb:Q96FQ4|uniprotkb:A9IZ92|uniprotkb:Q5JUY8|ensembl:ENSP00000361535 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:med8_human(display_long)|uniprotkb:MED8(gene name)|psi-mi:MED8(display_short)|uniprotkb:Mediator complex subunit 8(gene name synonym)|uniprotkb:Activator-recruited cofactor 32 kDa component(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_443109.2|refseq:NP_963836.2|refseq:NP_001001653.1|ensembl:ENSG00000159479(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|mint:Q96G25|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENST00000372457(transcript) - - comment:"author score: 66" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:e/ye7rfa2E1XOPb5vVhI9Nvqmxw9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:P05423 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-2687556|uniprotkb:Q9BXB3|uniprotkb:Q9BPZ1|uniprotkb:Q6FI28|uniprotkb:Q9BPV7|ensembl:ENSP00000303088|ensembl:ENSP00000380904 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:rpc4_human(display_long)|uniprotkb:BN51(gene name synonym)|uniprotkb:BN51T(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III subunit D(gene name synonym)|uniprotkb:Protein BN51(gene name synonym)|uniprotkb:RNA polymerase III 47 kDa subunit(gene name synonym)|uniprotkb:RPC53 homolog(gene name synonym)|uniprotkb:POLR3D(gene name)|psi-mi:POLR3D(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_001713.2|ensembl:ENSG00000168495(gene)|ensembl:ENST00000306433(transcript)|ensembl:ENST00000397802(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005829"(cytosol)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0045087"(innate immune response)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR007811(RNA polymerase III Rpc4)|mint:P05423|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|reactome:R-HSA-1834949|reactome:R-HSA-73780|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|dip:DIP-56155N - - comment:"author score: 67" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:nhavqSwnCIqzs0e5Gn/kabUmAXA9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:Q96HR3 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-394659|uniprotkb:C6GKU9|intact:EBI-11137618|ensembl:ENSP00000297347 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:med30_human(display_long)|uniprotkb:TRAP25(gene name synonym)|uniprotkb:MED30(gene name)|psi-mi:MED30(display_short)|uniprotkb:Mediator complex subunit 30(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein 6(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 25 kDa component(gene name synonym)|uniprotkb:TRAP/Mediator complex component TRAP25(gene name synonym)|uniprotkb:THRAP6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_542382.1|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021019|mint:Q96HR3|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|refseq:NP_001269915.1|ensembl:ENSG00000164758(gene)|ensembl:ENST00000297347(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003712"(transcription coregulator activity) - - comment:"author score: 67" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:dUgR7zxbKAcYqPKb8teHBLgUhWY9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:Q9H204 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-514199|uniprotkb:Q9BZJ5|ensembl:ENSP00000237380 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:med28_human(display_long)|uniprotkb:Mediator complex subunit 28(gene name synonym)|uniprotkb:Tumor angiogenesis marker EG-1(gene name synonym)|uniprotkb:Endothelial-derived protein 1(gene name synonym)|uniprotkb:Merlin and Grb2-interacting cytoskeletal protein(gene name synonym)|uniprotkb:MED28(gene name)|psi-mi:MED28(display_short)|uniprotkb:EG1(gene name synonym)|uniprotkb:FKSG20(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_079481.2|ensembl:ENSG00000118579(gene)|ensembl:ENST00000237380(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0051151"(negative regulation of smooth muscle cell differentiation)|interpro:IPR021640|mint:Q9H204|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 - - comment:"author score: 69" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:1gt/0vP7vWJ+M1fU+qZPcWGj34U9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:Q13503 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N - - comment:"author score: 71" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:O94763 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-357067|uniprotkb:A8K805|uniprotkb:Q9UNU3|intact:EBI-2683009|uniprotkb:H7BY42|uniprotkb:Q8TC23|ensembl:ENSP00000376097 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:rmp_human(display_long)|uniprotkb:URI1(gene name)|psi-mi:URI1(display_short)|uniprotkb:C19orf2(gene name synonym)|uniprotkb:NNX3(gene name synonym)|uniprotkb:PPP1R19(gene name synonym)|uniprotkb:Protein NNX3(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 19(gene name synonym)|uniprotkb:RMP(gene name synonym)|uniprotkb:RNA polymerase II subunit 5-mediating protein(gene name synonym)|uniprotkb:URI(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_003787.2|ensembl:ENSG00000105176(gene)|refseq:NP_001239570.1|ensembl:ENST00000392271(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009615"(response to virus)|go:"GO:0010923"(negative regulation of phosphatase activity)|go:"GO:0019212"(phosphatase inhibitor activity)|go:"GO:0030425"(dendrite)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|mint:O94763 - - comment:"author score: 73" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:izqLgjD5/WAkdmUp7K8hIQ+cGxE9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:Q9NPJ6 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 - - comment:"author score: 74" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:Bept2Oec50gruA9e4pf+eEUiANM9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:Q9H6T3 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-356928|uniprotkb:Q6PHR5|uniprotkb:B4DRW9|ensembl:ENSP00000005386 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:rpap3_human(display_long)|uniprotkb:RPAP3(gene name)|psi-mi:RPAP3(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_001139547.1|refseq:NP_001139548.1|refseq:NP_078880.2|dip:DIP-47508N|ensembl:ENSG00000005175(gene)|ensembl:ENST00000005386(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0097255"(R2TP complex)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR025986|mint:Q9H6T3|rcsb pdb:4CGV|rcsb pdb:4CGW|rcsb pdb:6EZ4|rcsb pdb:6FD7|rcsb pdb:6FDP|rcsb pdb:6FDT|rcsb pdb:6FM8|rcsb pdb:6FO1|rcsb pdb:6GXZ|rcsb pdb:6ZBK - - comment:"author score: 76" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:pN6/ClY+oonHFRAFtpcGeZ/OTEQ9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:Q9BTT4 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-394354|uniprotkb:C6G491|ensembl:ENSP00000255764 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:med10_human(display_long)|uniprotkb:MED10(gene name)|psi-mi:MED10(display_short)|uniprotkb:L6(orf name)|uniprotkb:TRG17(orf name)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Transformation-related gene 17 protein(gene name synonym)|uniprotkb:Transformation-related gene 20 protein(gene name synonym)|uniprotkb:TRG20(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N ensembl:ENSG00000133398(gene)|ensembl:ENST00000255764(transcript)|refseq:NP_115662.2|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019145|mint:Q9BTT4|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|go:"GO:0000151"(ubiquitin ligase complex)|dip:DIP-31457N - - comment:"author score: 77" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:LzJW7C8kl2pWmffOjo8S/FNSS9I9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:Q9Y535 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-2515065|uniprotkb:Q9BY95|uniprotkb:Q96AE3|uniprotkb:B0QYH9|uniprotkb:Q5M7Y8|ensembl:ENSP00000347345|ensembl:ENSP00000379761|ensembl:ENSP00000385315 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:rpc8_human(display_long)|uniprotkb:POLR3H(gene name)|psi-mi:POLR3H(display_short)|uniprotkb:KIAA1665(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III subunit H(gene name synonym)|uniprotkb:RPC8(gene name synonym)|uniprotkb:RNA polymerase III subunit 22.9 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_001269813.1|refseq:NP_001269814.1|refseq:NP_001018060.1|refseq:NP_001018062.1|refseq:NP_612211.1|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|ensembl:ENSG00000100413(gene)|ensembl:ENST00000355209(transcript)|ensembl:ENST00000396504(transcript)|ensembl:ENST00000407461(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0006384"(transcription initiation from RNA polymerase III promoter)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR004519(DNA-directed RNA polymerase)|interpro:IPR005576(RNA polymerase Rpb7, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013238(RNA polymerase III, subunit Rpc25)|interpro:IPR036898|mint:Q9Y535|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|reactome:R-HSA-1834949|reactome:R-HSA-73780 - - comment:"author score: 78" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:iZrzO9t581Oy9db2/+cpcy7uLL09606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:O14802 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-2515113|ensembl:ENSP00000361446|uniprotkb:Q8TCW5|uniprotkb:Q8IW34 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:rpc1_human(display_long)|uniprotkb:POLR3A(gene name)|psi-mi:POLR3A(display_short)|uniprotkb:DNA-directed RNA polymerase III subunit A(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:RNA polymerase III 155 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase III subunit C160(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N ensembl:ENSG00000148606(gene)|ensembl:ENST00000372371(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0016020"(membrane)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0045087"(innate immune response)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR035697|interpro:IPR035698|interpro:IPR038120|interpro:IPR042102|mint:O14802|rcsb pdb:7A6H|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|reactome:R-HSA-1834949|reactome:R-HSA-73780|reactome:R-HSA-73980|reactome:R-HSA-749476|rcsb pdb:7AE1|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|refseq:NP_008986.2 - - comment:"author score: 79" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:aIkROXC0f3CXTeRzAvW+lyXSmTE9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:Q9NVU0 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-2515048|ensembl:ENSP00000299853|ensembl:ENSP00000492514|ensembl:ENSP00000492263|uniprotkb:B4DL24|uniprotkb:Q9H8W8|uniprotkb:Q9H907|uniprotkb:Q9BWF7|uniprotkb:Q9P276|uniprotkb:B4DUP6|uniprotkb:H3BT11 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:rpc5_human(display_long)|uniprotkb:POLR3E(gene name)|psi-mi:POLR3E(display_short)|uniprotkb:KIAA1452(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III 80 kDa polypeptide(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N ensembl:ENSG00000058600(gene)|ensembl:ENSG00000284282(gene)|ensembl:ENST00000299853(transcript)|ensembl:ENST00000639550(transcript)|ensembl:ENST00000640588(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR006886(Sin-like protein conserved region)|mint:Q9NVU0|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7ASU|rcsb pdb:7ASV|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DU2|reactome:R-HSA-1834949|reactome:R-HSA-73780|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|rcsb pdb:7DN3|refseq:NP_060589.1|refseq:NP_001244964.1|refseq:NP_001244965.1|refseq:NP_001244962.1|refseq:NP_001244963.1|refseq:XP_006721126.1|refseq:XP_006726676.1 - - comment:"author score: 82" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:X4MAZK4RTaqr2QmPSRgaSnxD8zY9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:P0DPB6 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-359498|uniprotkb:Q9Y2S0|ensembl:ENSP00000302478|uniprotkb:Q5TBX2|uniprotkb:Q96BR3 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:rpac2_human(display_long)|uniprotkb:POLR1D(gene name)|psi-mi:POLR1D(display_short)|uniprotkb:DNA-directed RNA polymerase I subunit D(gene name synonym)|uniprotkb:RPC16(gene name synonym)|uniprotkb:hRPA19(gene name synonym)|uniprotkb:AC19(gene name synonym)|uniprotkb:RNA polymerase I 16 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N mint:P0DPB6|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|ensembl:ENSG00000186184(gene)|ensembl:ENST00000302979(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR008193(DNA-directed RNA polymerase Rpb11, 13-16 kDa subunit, conserved site)|interpro:IPR009025(DNA-directed RNA polymerase, RBP11-like)|interpro:IPR033898|interpro:IPR036603|refseq:NP_057056.1|refseq:XP_005266469.1 - - comment:"author score: 85" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:rDbtR47SoszVxupqkWmoxVTS4/E9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:Q96MX6 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-2434101|uniprotkb:Q96CR6|ensembl:ENSP00000295121 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:daa10_human(display_long)|uniprotkb:DNAAF10(gene name)|psi-mi:DNAAF10(display_short)|uniprotkb:WD repeat-containing protein 92(gene name synonym)|uniprotkb:WD repeat-containing protein Monad(gene name synonym)|uniprotkb:WDR92(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_612467.1|refseq:NP_001243405.1|ensembl:ENSG00000243667(gene)|ensembl:ENST00000295121(transcript)|go:"GO:0006915"(apoptotic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0070286"(axonemal dynein complex assembly)|go:"GO:0120293"(dynein axonemal particle)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q96MX6|rcsb pdb:3I2N - - comment:"author score: 85" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:mMEdSK0cmIF+8Bayok/snQBKYMg9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:Q9H9Y6 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-355441|uniprotkb:Q6ZRR2|uniprotkb:Q9H9D3|uniprotkb:Q585T5|uniprotkb:B7Z6Y7|uniprotkb:B7Z823|uniprotkb:F5GZX4|uniprotkb:F8W898|uniprotkb:Q2TAM4|ensembl:ENSP00000263331 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:rpa2_human(display_long)|uniprotkb:POLR1B(gene name)|psi-mi:POLR1B(display_short)|uniprotkb:DNA-directed RNA polymerase I 135 kDa polypeptide(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_001131076.1|refseq:NP_061887.2|refseq:NP_001269703.1|refseq:NP_001269705.1|refseq:NP_001269706.1|refseq:NP_001269708.1|refseq:NP_001269701.1|dip:DIP-27538N|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR009674(RNA polymerase I, Rpa2 specific)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|mint:Q9H9Y6|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73863|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|ensembl:ENSG00000125630(gene)|ensembl:ENST00000263331(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0007566"(embryo implantation)|go:"GO:0009303"(rRNA transcription)|go:"GO:0014029"(neural crest formation)|go:"GO:0017126"(nucleologenesis)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding) - - comment:"author score: 99" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:enAJckjxEU6bE3J3OA5pFREXC3U9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:Q5VT52 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-372367|uniprotkb:O75048|uniprotkb:Q5VT53|uniprotkb:Q6MZL4|uniprotkb:Q86XD2|uniprotkb:A8K6N8|uniprotkb:B3KPT1|uniprotkb:Q5VT51|uniprotkb:Q9P0D7|uniprotkb:B4E2Q6|ensembl:ENSP00000358064 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:rprd2_human(display_long)|uniprotkb:RPRD2(gene name)|psi-mi:RPRD2(display_short)|uniprotkb:KIAA0460(gene name synonym)|uniprotkb:HSPC099(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_056018.2|ensembl:ENSG00000163125(gene)|ensembl:ENST00000369068(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q5VT52|rcsb pdb:4FLB|reactome:R-HSA-6807505|refseq:NP_001284602.1|refseq:NP_001284603.1|dip:DIP-31155N - - comment:"author score: 113" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:HbkwBBEJ+MNQOjJ2nezU7MJMHYQ9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:O95602 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-359472|uniprotkb:Q9UEH0|uniprotkb:Q9UFT9|uniprotkb:Q0VG05|uniprotkb:B7Z7T0|uniprotkb:D6W5M0|ensembl:ENSP00000263857 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:rpa1_human(display_long)|uniprotkb:POLR1A(gene name)|psi-mi:POLR1A(display_short)|uniprotkb:DNA-directed RNA polymerase I subunit A(gene name synonym)|uniprotkb:DNA-directed RNA polymerase I largest subunit(gene name synonym)|uniprotkb:RNA polymerase I 194 kDa subunit(gene name synonym)|uniprotkb:A190(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_056240.2|ensembl:ENST00000263857(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0008270"(zinc ion binding)|go:"GO:1904750"(negative regulation of protein localization to nucleolus)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR015699(DNA-directed RNA pol I, largest subunit)|interpro:IPR038120|interpro:IPR042102|mint:O95602|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73863|ensembl:ENSG00000068654(gene)|dip:DIP-27537N - - comment:"author score: 123" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:EDNwLyujEW01bH48PD19pr3/lgU9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:O15160 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-1055079|uniprotkb:O75395|uniprotkb:Q5JTE3|ensembl:ENSP00000496044 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:rpac1_human(display_long)|uniprotkb:DNA-directed RNA polymerases I and III 40 kDa polypeptide(gene name synonym)|uniprotkb:RPC40(gene name synonym)|uniprotkb:AC40(gene name synonym)|uniprotkb:RPA39(gene name synonym)|uniprotkb:POLR1C(gene name)|psi-mi:POLR1C(display_short)|uniprotkb:POLR1E(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_001305805.1|refseq:NP_976035.1|ensembl:ENSG00000171453(gene)|ensembl:ENST00000642195(transcript)|go:"GO:0001054"(RNA polymerase I activity)|go:"GO:0001056"(RNA polymerase III activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001514(DNA-directed RNA polymerase, 30-40 kDa subunit, conserved site)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR033901|interpro:IPR036603|interpro:IPR036643|mint:O15160|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|reactome:R-HSA-1834949|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|dip:DIP-27587N - - comment:"author score: 134" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:xSIuJ9kjLRZ6Vc9EnLdvX/CBJKU9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:Q8IXW5 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-395878|uniprotkb:Q49AS7|uniprotkb:Q9H8Y2|ensembl:ENSP00000476948|uniprotkb:C9JKB5 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:rpap2_human(display_long)|uniprotkb:RPAP2(gene name)|psi-mi:RPAP2(display_short)|uniprotkb:C1orf82(gene name synonym)|uniprotkb:RNA polymerase II-associated protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_079089.2|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008420"(RNA polymerase II CTD heptapeptide repeat phosphatase activity)|go:"GO:0009301"(snRNA transcription)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0043175"(RNA polymerase core enzyme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR007308(Protein of unknown function DUF408)|interpro:IPR038534|interpro:IPR039693|mint:Q8IXW5|rcsb pdb:7B7U|reactome:R-HSA-6807505|ensembl:ENSG00000122484(gene)|ensembl:ENST00000610020(transcript)|go:"GO:0005634"(nucleus)|dip:DIP-32939N - - comment:"author score: 149" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:niEFEvqkASycxkzfe9TYJuerUuY9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:P0CAP2 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-9657655|uniprotkb:Q96NF5|uniprotkb:Q6EFN8|uniprotkb:Q6EEV3|uniprotkb:Q9Y3V6|uniprotkb:Q8NC58|uniprotkb:Q96DI5|uniprotkb:Q6EF02|uniprotkb:Q6K050|uniprotkb:Q6K046|uniprotkb:Q6K051|uniprotkb:Q6EF01|uniprotkb:Q6EES2|uniprotkb:Q8NCF3|uniprotkb:Q6EM48|uniprotkb:Q6EF46|uniprotkb:Q6ZQZ3|uniprotkb:Q6EER8|uniprotkb:Q96JB7|uniprotkb:Q6EF00|ensembl:ENSP00000299638 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:grl1a_human(display_long)|uniprotkb:POLR2M(gene name)|psi-mi:POLR2M(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit M(gene name synonym)|uniprotkb:GRINL1A(gene name synonym)|uniprotkb:Glutamate receptor-like protein 1A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_001018112.1|refseq:NP_056347.1|dip:DIP-61933N|ensembl:ENSG00000255529(gene)|ensembl:ENST00000299638(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051685"(maintenance of ER location)|interpro:IPR026213|mint:P0CAP2|rcsb pdb:6DRD - - comment:"author score: 156" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:G0QVxeD0uvJTl0VPn+b3pV6zLe89606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:P62875 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-359527|ensembl:ENSP00000324124|ensembl:ENSP00000432807|uniprotkb:P52436|uniprotkb:Q6FHX3 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:rpab5_human(display_long)|uniprotkb:POLR2L(gene name)|psi-mi:POLR2L(display_short)|uniprotkb:DNA-directed RNA polymerase III subunit L(gene name synonym)|uniprotkb:RPB10 homolog(gene name synonym)|uniprotkb:RNA polymerase II 7.6 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N ensembl:ENSG00000177700(gene)|ensembl:ENST00000322028(transcript)|ensembl:ENST00000534030(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006356"(regulation of transcription by RNA polymerase I)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR000268(RNA polymerases, N/8 Kd subunits)|interpro:IPR020789|interpro:IPR023580|mint:P62875|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|refseq:NP_066951.1|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-75955|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-203927|dip:DIP-32960N - - comment:"author score: 156" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:uDzgKgHzFTPxFaV1GeUYdYMa4Gk9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:O15514 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N - - comment:"author score: 211" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:Q9NQG5 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-747925|uniprotkb:Q1WDE7|uniprotkb:Q6PKF4|ensembl:ENSP00000362532 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:rpr1b_human(display_long)|uniprotkb:RPRD1B(gene name)|psi-mi:RPRD1B(display_short)|uniprotkb:C20orf77(gene name synonym)|uniprotkb:CREPT(gene name synonym)|uniprotkb:Cell cycle-related and expression-elevated protein in tumor(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_067038.1|ensembl:ENSG00000101413(gene)|ensembl:ENST00000373433(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q9NQG5|rcsb pdb:4FLA|rcsb pdb:4FU3|rcsb pdb:4HFG|rcsb pdb:4NAD|rcsb pdb:4Q94|rcsb pdb:4Q96|reactome:R-HSA-6807505|dip:DIP-61537N - - comment:"author score: 211" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:1P0sOiLV5eQXrRj+vENpc6L/z/Q9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:P52435 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-394753|uniprotkb:O43375|uniprotkb:A5D6V8|ensembl:ENSP00000292614 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:rpb11_human(display_long)|uniprotkb:POLR2J(gene name)|psi-mi:POLR2J(display_short)|uniprotkb:POLR2J1(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II subunit J-1(gene name synonym)|uniprotkb:RNA polymerase II 13.3 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_006225.1|ensembl:ENSG00000005075(gene)|ensembl:ENST00000292614(transcript)|go:"GO:0001055"(RNA polymerase II activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0030275"(LRR domain binding)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR008193(DNA-directed RNA polymerase Rpb11, 13-16 kDa subunit, conserved site)|interpro:IPR009025(DNA-directed RNA polymerase, RBP11-like)|interpro:IPR036603|interpro:IPR037685|mint:P52435|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32913N - - comment:"author score: 219" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:jK/DlwFrHHuEJ0Ns3wRoB3icmsA9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:Q96P16 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-1053506|uniprotkb:Q7Z5G8|uniprotkb:Q96FY9|uniprotkb:Q9NVL4|uniprotkb:A8KA42|uniprotkb:B2RBA3|ensembl:ENSP00000349955|ensembl:ENSP00000381984 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:rpr1a_human(display_long)|uniprotkb:RPRD1A(gene name)|psi-mi:RPRD1A(display_short)|uniprotkb:p15INK4B-related protein(gene name synonym)|uniprotkb:P15RS(gene name synonym)|uniprotkb:Cyclin-dependent kinase inhibitor 2B-related protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:XP_011524350.1|refseq:XP_011524351.1|refseq:XP_011524352.1|refseq:NP_060640.2|refseq:NP_001290340.1|refseq:NP_001290341.1|refseq:NP_001290342.1|ensembl:ENSG00000141425(gene)|ensembl:ENST00000357384(transcript)|ensembl:ENST00000399022(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q96P16|rcsb pdb:4JXT|rcsb pdb:4NAC|reactome:R-HSA-6807505|dip:DIP-50901N - - comment:"author score: 220" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:RGCJx8nL9gil6DmtiiFboxeNUSU9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:P30876 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-394712|uniprotkb:Q8IZ61|uniprotkb:A8K1A8|ensembl:ENSP00000312735|ensembl:ENSP00000370625 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:rpb2_human(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit B(gene name synonym)|uniprotkb:RNA polymerase II subunit B2(gene name synonym)|uniprotkb:RNA polymerase II subunit 2(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 140 kDa polypeptide(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_000929.1|refseq:NP_001290197.1|refseq:NP_001290198.1|ensembl:ENSG00000047315(gene)|ensembl:ENST00000314595(transcript)|ensembl:ENST00000381227(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|mint:P30876|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32910N - - comment:"author score: 262" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:YhEjtfLk2QnbRPefOp8ZHX0ejak9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:P24928 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-295301|uniprotkb:A6NN93|uniprotkb:B9EH88|uniprotkb:Q6NX41|intact:EBI-17957133|intact:EBI-14758660|intact:EBI-13324911|intact:EBI-23311874 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:rpb1_human(display_long)|uniprotkb:POLR2A(gene name)|psi-mi:POLR2A(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit A(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:POLR2(gene name synonym)|uniprotkb:RNA-directed RNA polymerase II subunit RPB1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_000928.1|mint:P24928|dip:DIP-29011N|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0019900"(kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:2GHQ|rcsb pdb:2GHT|rcsb pdb:2LTO|rcsb pdb:3D9K|rcsb pdb:3D9L|rcsb pdb:3D9M|rcsb pdb:3D9N|rcsb pdb:3D9O|rcsb pdb:3D9P|rcsb pdb:4JXT|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:5M3H|rcsb pdb:5M3J|rcsb pdb:6DRD|rcsb pdb:6F5P|rcsb pdb:6G0R|rcsb pdb:6IC8|rcsb pdb:6IC9|rcsb pdb:6O9L|rcsb pdb:6Q5Y|rcsb pdb:6XKB|rcsb pdb:6XRE|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095 - - comment:"author score: 266" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:Si2fgh4AMaNtlzvSQhvsuPusX7s9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:P62487 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-347928|ensembl:ENSP00000301788|uniprotkb:P52433|uniprotkb:Q2M1Z4|uniprotkb:B2R5C0 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:rpb7_human(display_long)|uniprotkb:POLR2G(gene name)|psi-mi:POLR2G(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit G(gene name synonym)|uniprotkb:RPB7(gene name synonym)|uniprotkb:RNA polymerase II 19 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N ensembl:ENSG00000168002(gene)|ensembl:ENST00000301788(transcript)|go:"GO:0000291"(nuclear-transcribed mRNA catabolic process, exonucleolytic)|go:"GO:0000932"(P-body)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006915"(apoptotic process)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR003029(S1, RNA binding)|interpro:IPR005576(RNA polymerase Rpb7, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR036898|mint:P62487|rcsb pdb:2C35|rcsb pdb:5IYA|rcsb pdb:5IY6|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|rcsb pdb:5IY7|reactome:R-HSA-167200|reactome:R-HSA-167238|rcsb pdb:5IY8|rcsb pdb:5IY9|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-5601884|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|refseq:NP_002687.1|dip:DIP-32663N - - comment:"author score: 267" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:MtnIweuhSqLFov0c40uOiwv8Eas9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:P36954 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-395202|uniprotkb:Q6NW05|uniprotkb:B2R5J2|ensembl:ENSP00000221859 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:rpb9_human(display_long)|uniprotkb:POLR2I(gene name)|psi-mi:POLR2I(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit I(gene name synonym)|uniprotkb:RNA polymerase II 14.5 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_006224.1|ensembl:ENSG00000105258(gene)|ensembl:ENST00000221859(transcript)|go:"GO:0001193"(maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034012|mint:P36954|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32917N - - comment:"author score: 293" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:YZUW2UDzj1RhCC46iaX1LvYayNA9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:P52434 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-359505|uniprotkb:P53802|uniprotkb:Q969R0|ensembl:ENSP00000392913|uniprotkb:C9J413|uniprotkb:C9JBJ6|uniprotkb:C9JCU7|uniprotkb:C9JUA8 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:rpab3_human(display_long)|uniprotkb:POLR2H(gene name)|psi-mi:POLR2H(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit H(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I, II, and III 17.1 kDa polypeptide(gene name synonym)|uniprotkb:RPB17(gene name synonym)|uniprotkb:RPB8 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N ensembl:ENSG00000163882(gene)|ensembl:ENST00000456318(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032993"(protein-DNA complex)|interpro:IPR005570(RNA polymerase, Rpb8)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:P52434|rcsb pdb:2F3I|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|refseq:NP_006223.2|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|rcsb pdb:7AE3|reactome:R-HSA-1834949|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-427413|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-203927|refseq:NP_001265627.1|refseq:NP_001265628.1|refseq:NP_001265629.1|refseq:NP_001265644.1|refseq:NP_001265643.1|refseq:XP_006713729.1|refseq:XP_006713730.1|refseq:XP_016862125.1|refseq:XP_016862126.1|dip:DIP-27556N - - comment:"author score: 295" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:h7BRWDi8wRbnw/FcFo25bnlVNkE9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P19388 uniprotkb:P19387 intact:EBI-395189|uniprotkb:O43380|uniprotkb:Q6PIH5|uniprotkb:Q9BT06|uniprotkb:B2R6L4|uniprotkb:D6W5Y1|ensembl:ENSP00000464739|ensembl:ENSP00000478303|ensembl:ENSP00000485021 intact:EBI-394729|uniprotkb:O15161|ensembl:ENSP00000219252 psi-mi:rpab1_human(display_long)|uniprotkb:POLR2E(gene name)|psi-mi:POLR2E(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit E(gene name synonym)|uniprotkb:RPB5 homolog(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 23 kDa polypeptide(gene name synonym)|uniprotkb:XAP4(gene name synonym) psi-mi:rpb3_human(display_long)|uniprotkb:POLR2C(gene name)|psi-mi:POLR2C(display_short)|uniprotkb:A-152E5.7(orf name)|uniprotkb:DNA-directed RNA polymerase II subunit C(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 33 kDa polypeptide(gene name synonym)|uniprotkb:RPB31(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482739|imex:IM-26985-421 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002686.2|ensembl:ENSG00000099817(gene)|ensembl:ENST00000586746(transcript)|ensembl:ENST00000612655(transcript)|ensembl:ENST00000615234(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR000783(RNA polymerase, subunit H/Rpb5 C-terminal)|interpro:IPR005571(RNA polymerase, Rpb5, N-terminal)|interpro:IPR014381(DNA-directed RNA polymerase, RPB5 subunit)|interpro:IPR020608|interpro:IPR020609|interpro:IPR035913|interpro:IPR036710|interpro:IPR039531|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|mint:P19388|rcsb pdb:5IY6|rcsb pdb:5IY7|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-167246|dip:DIP-56N refseq:NP_116558.1|ensembl:ENSG00000102978(gene)|ensembl:ENST00000219252(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001514(DNA-directed RNA polymerase, 30-40 kDa subunit, conserved site)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR036603|interpro:IPR036643|mint:P19387|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32911N - - comment:"author score: 296" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BIVesx7KODhdpcgjhU6CghhXNQE9606 rogid:UXFC+i+QqB2WRgL9OiYSQ66L36c9606 rigid:Nl1g1tErfUBX32/a67DjqO/LUO8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNP9 uniprotkb:P51608 intact:EBI-591818|uniprotkb:Q3S611|uniprotkb:Q5TGA3|uniprotkb:O43634|uniprotkb:O43635|uniprotkb:Q32Q72|uniprotkb:Q5TGA0|uniprotkb:Q5TGA2|uniprotkb:Q9UIZ5|uniprotkb:B2R971|ensembl:ENSP00000312769 intact:EBI-1189067|uniprotkb:O15233|uniprotkb:Q6QHH9|uniprotkb:Q7Z384|ensembl:ENSP00000301948 psi-mi:ppie_human(display_long)|uniprotkb:Cyclophilin E(gene name synonym)|uniprotkb:Cyclophilin-33(gene name synonym)|uniprotkb:PPIE(gene name)|psi-mi:PPIE(display_short)|uniprotkb:CYP33(gene name synonym)|uniprotkb:Rotamase E(gene name synonym) psi-mi:mecp2_human(display_long)|uniprotkb:MECP2(gene name)|psi-mi:MECP2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483015|imex:IM-26985-199 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006103.1|refseq:NP_982281.1|refseq:NP_001181936.1|refseq:XP_016855540.1|dip:DIP-34757N|ensembl:ENSG00000084072(gene)|ensembl:ENST00000324379(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR016304(Peptidyl-prolyl cis-trans isomerase E)|interpro:IPR020892|interpro:IPR029000|interpro:IPR034168|interpro:IPR035979|mint:Q9UNP9|rcsb pdb:1ZMF|rcsb pdb:2CQB|rcsb pdb:2KU7|rcsb pdb:2KYX|rcsb pdb:2R99|rcsb pdb:3LPY|rcsb pdb:3MDF|rcsb pdb:3UCH|rcsb pdb:5MQF|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6798695|reactome:R-HSA-72163 refseq:NP_001104262.1|refseq:NP_004983.1|refseq:NP_001303266.1|ensembl:ENSG00000169057(gene)|ensembl:ENST00000303391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0001662"(behavioral fear response)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001964"(startle response)|go:"GO:0001976"(nervous system process involved in regulation of systemic arterial blood pressure)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006020"(inositol metabolic process)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006576"(cellular biogenic amine metabolic process)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007416"(synapse assembly)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0007616"(long-term memory)|go:"GO:0008104"(protein localization)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016358"(dendrite development)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016571"(histone methylation)|go:"GO:0016573"(histone acetylation)|go:"GO:0019230"(proprioception)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021591"(ventricular system development)|go:"GO:0032048"(cardiolipin metabolic process)|go:"GO:0035176"(social behavior)|go:"GO:0035197"(siRNA binding)|go:"GO:0042551"(neuron maturation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051151"(negative regulation of smooth muscle cell differentiation)|go:"GO:0051707"(response to other organism)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0098794"(postsynapse)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|go:"GO:1905643"(positive regulation of DNA methylation)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000820"(negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR017353(Methyl-CpG binding protein MeCP2)|mint:P51608|rcsb pdb:1QK9|rcsb pdb:3C2I|rcsb pdb:5BT2|rcsb pdb:6C1Y|rcsb pdb:6OGJ|rcsb pdb:6OGK|reactome:R-HSA-8986944|reactome:R-HSA-9022534|reactome:R-HSA-9022535|reactome:R-HSA-9022537|reactome:R-HSA-9022538|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9022702|reactome:R-HSA-9022707|reactome:R-HSA-9022927|dip:DIP-39983N - - comment:"author score: 39" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:zMkadgyIl5RwvoD3h3vetTqLjg49606 rogid:7c5ZZAZsqV7AciGN4hzFNWJLeUk9606 rigid:ePN9/9kkv7wxoUtWV71kSSRrIwQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNP9 uniprotkb:O60306 intact:EBI-591818|uniprotkb:Q3S611|uniprotkb:Q5TGA3|uniprotkb:O43634|uniprotkb:O43635|uniprotkb:Q32Q72|uniprotkb:Q5TGA0|uniprotkb:Q5TGA2|uniprotkb:Q9UIZ5|uniprotkb:B2R971|ensembl:ENSP00000312769 intact:EBI-2512328|ensembl:ENSP00000156471|uniprotkb:Q2YDX9|uniprotkb:Q6PIC8|uniprotkb:Q6IRU8|uniprotkb:A0JP17|uniprotkb:A5YKK3 psi-mi:ppie_human(display_long)|uniprotkb:Cyclophilin E(gene name synonym)|uniprotkb:Cyclophilin-33(gene name synonym)|uniprotkb:PPIE(gene name)|psi-mi:PPIE(display_short)|uniprotkb:CYP33(gene name synonym)|uniprotkb:Rotamase E(gene name synonym) psi-mi:aqr_human(display_long)|uniprotkb:AQR(gene name)|psi-mi:AQR(display_short)|uniprotkb:KIAA0560(gene name synonym)|uniprotkb:Intron-binding protein of 160 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483015|imex:IM-26985-199 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006103.1|refseq:NP_982281.1|refseq:NP_001181936.1|refseq:XP_016855540.1|dip:DIP-34757N|ensembl:ENSG00000084072(gene)|ensembl:ENST00000324379(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR016304(Peptidyl-prolyl cis-trans isomerase E)|interpro:IPR020892|interpro:IPR029000|interpro:IPR034168|interpro:IPR035979|mint:Q9UNP9|rcsb pdb:1ZMF|rcsb pdb:2CQB|rcsb pdb:2KU7|rcsb pdb:2KYX|rcsb pdb:2R99|rcsb pdb:3LPY|rcsb pdb:3MDF|rcsb pdb:3UCH|rcsb pdb:5MQF|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6798695|reactome:R-HSA-72163 ensembl:ENSG00000021776(gene)|ensembl:ENST00000156471(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0034458"(3'-5' RNA helicase activity)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR026300|interpro:IPR027417|interpro:IPR032174|interpro:IPR041677|interpro:IPR041679|mint:O60306|rcsb pdb:4PJ3|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163|refseq:NP_055506.1|dip:DIP-53576N - - comment:"author score: 52" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:zMkadgyIl5RwvoD3h3vetTqLjg49606 rogid:ZkD96by9PXxdrXPBXE+ZTaZeGnM9606 rigid:ePN9/9kkv7wxoUtWV71kSSRrIwQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNP9 uniprotkb:Q96NB3 intact:EBI-591818|uniprotkb:Q3S611|uniprotkb:Q5TGA3|uniprotkb:O43634|uniprotkb:O43635|uniprotkb:Q32Q72|uniprotkb:Q5TGA0|uniprotkb:Q5TGA2|uniprotkb:Q9UIZ5|uniprotkb:B2R971|ensembl:ENSP00000312769 intact:EBI-3920997|ensembl:ENSP00000354518|uniprotkb:Q96F60|uniprotkb:Q96GZ5|uniprotkb:Q9BU38 psi-mi:ppie_human(display_long)|uniprotkb:Cyclophilin E(gene name synonym)|uniprotkb:Cyclophilin-33(gene name synonym)|uniprotkb:PPIE(gene name)|psi-mi:PPIE(display_short)|uniprotkb:CYP33(gene name synonym)|uniprotkb:Rotamase E(gene name synonym) psi-mi:zn830_human(display_long)|uniprotkb:ZNF830(gene name)|psi-mi:ZNF830(display_short)|uniprotkb:CCDC16(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 16(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483015|imex:IM-26985-199 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006103.1|refseq:NP_982281.1|refseq:NP_001181936.1|refseq:XP_016855540.1|dip:DIP-34757N|ensembl:ENSG00000084072(gene)|ensembl:ENST00000324379(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR016304(Peptidyl-prolyl cis-trans isomerase E)|interpro:IPR020892|interpro:IPR029000|interpro:IPR034168|interpro:IPR035979|mint:Q9UNP9|rcsb pdb:1ZMF|rcsb pdb:2CQB|rcsb pdb:2KU7|rcsb pdb:2KYX|rcsb pdb:2R99|rcsb pdb:3LPY|rcsb pdb:3MDF|rcsb pdb:3UCH|rcsb pdb:5MQF|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6798695|reactome:R-HSA-72163 ensembl:ENSG00000198783(gene)|ensembl:ENST00000361952(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001546"(preantral ovarian follicle growth)|go:"GO:0001832"(blastocyst growth)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005694"(chromosome)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033260"(nuclear DNA replication)|go:"GO:0033314"(mitotic DNA replication checkpoint signaling)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044773"(mitotic DNA damage checkpoint signaling)|go:"GO:0048478"(replication fork protection)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|go:"GO:0060729"(intestinal epithelial structure maintenance)|interpro:IPR003604(Zinc finger, U1-type)|interpro:IPR036236|interpro:IPR040050|mint:Q96NB3|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|refseq:NP_443089.3|dip:DIP-61544N - - comment:"author score: 72" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:zMkadgyIl5RwvoD3h3vetTqLjg49606 rogid:4PbBUxZP6ipr8qKoU7JWlkldInE9606 rigid:ePN9/9kkv7wxoUtWV71kSSRrIwQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNP9 uniprotkb:Q9ULR0 intact:EBI-591818|uniprotkb:Q3S611|uniprotkb:Q5TGA3|uniprotkb:O43634|uniprotkb:O43635|uniprotkb:Q32Q72|uniprotkb:Q5TGA0|uniprotkb:Q5TGA2|uniprotkb:Q9UIZ5|uniprotkb:B2R971|ensembl:ENSP00000312769 intact:EBI-2557660|uniprotkb:Q9BT05|uniprotkb:Q96IL2|ensembl:ENSP00000376973 psi-mi:ppie_human(display_long)|uniprotkb:Cyclophilin E(gene name synonym)|uniprotkb:Cyclophilin-33(gene name synonym)|uniprotkb:PPIE(gene name)|psi-mi:PPIE(display_short)|uniprotkb:CYP33(gene name synonym)|uniprotkb:Rotamase E(gene name synonym) psi-mi:isy1_human(display_long)|uniprotkb:ISY1(gene name)|psi-mi:ISY1(display_short)|uniprotkb:KIAA1160(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483015|imex:IM-26985-199 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006103.1|refseq:NP_982281.1|refseq:NP_001181936.1|refseq:XP_016855540.1|dip:DIP-34757N|ensembl:ENSG00000084072(gene)|ensembl:ENST00000324379(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR016304(Peptidyl-prolyl cis-trans isomerase E)|interpro:IPR020892|interpro:IPR029000|interpro:IPR034168|interpro:IPR035979|mint:Q9UNP9|rcsb pdb:1ZMF|rcsb pdb:2CQB|rcsb pdb:2KU7|rcsb pdb:2KYX|rcsb pdb:2R99|rcsb pdb:3LPY|rcsb pdb:3MDF|rcsb pdb:3UCH|rcsb pdb:5MQF|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6798695|reactome:R-HSA-72163 refseq:NP_001186398.1|refseq:NP_001191819.1|refseq:NP_065752.1|dip:DIP-56636N|ensembl:ENSG00000240682(gene)|ensembl:ENST00000393295(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0071020"(post-spliceosomal complex)|interpro:IPR009360(Isy1-like splicing)|interpro:IPR029012|interpro:IPR037200|mint:Q9ULR0|rcsb pdb:5YZG|rcsb pdb:6FF7|rcsb pdb:6ZYM|rcsb pdb:7A5P|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163 - - comment:"author score: 103" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:zMkadgyIl5RwvoD3h3vetTqLjg49606 rogid:t4QKu0uotUIJIzR8DTXWje21U1A9606 rigid:ePN9/9kkv7wxoUtWV71kSSRrIwQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UNP9 uniprotkb:Q9HCS7 intact:EBI-591818|uniprotkb:Q3S611|uniprotkb:Q5TGA3|uniprotkb:O43634|uniprotkb:O43635|uniprotkb:Q32Q72|uniprotkb:Q5TGA0|uniprotkb:Q5TGA2|uniprotkb:Q9UIZ5|uniprotkb:B2R971|ensembl:ENSP00000312769 intact:EBI-295232|uniprotkb:Q8TET6|uniprotkb:Q96HB0|uniprotkb:Q96IW0|uniprotkb:Q9NRG6|uniprotkb:Q9ULP3|ensembl:ENSP00000351137 psi-mi:ppie_human(display_long)|uniprotkb:Cyclophilin E(gene name synonym)|uniprotkb:Cyclophilin-33(gene name synonym)|uniprotkb:PPIE(gene name)|psi-mi:PPIE(display_short)|uniprotkb:CYP33(gene name synonym)|uniprotkb:Rotamase E(gene name synonym) psi-mi:syf1_human(display_long)|uniprotkb:XAB2(gene name)|psi-mi:XAB2(display_short)|uniprotkb:HCNP(gene name synonym)|uniprotkb:KIAA1177(gene name synonym)|uniprotkb:PP3898(orf name)|uniprotkb:SYF1(gene name synonym)|uniprotkb:XPA-binding protein 2(gene name synonym)|uniprotkb:Protein HCNP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483015|imex:IM-26985-199 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006103.1|refseq:NP_982281.1|refseq:NP_001181936.1|refseq:XP_016855540.1|dip:DIP-34757N|ensembl:ENSG00000084072(gene)|ensembl:ENST00000324379(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR016304(Peptidyl-prolyl cis-trans isomerase E)|interpro:IPR020892|interpro:IPR029000|interpro:IPR034168|interpro:IPR035979|mint:Q9UNP9|rcsb pdb:1ZMF|rcsb pdb:2CQB|rcsb pdb:2KU7|rcsb pdb:2KYX|rcsb pdb:2R99|rcsb pdb:3LPY|rcsb pdb:3MDF|rcsb pdb:3UCH|rcsb pdb:5MQF|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6798695|reactome:R-HSA-72163 refseq:NP_064581.2|dip:DIP-31646N|ensembl:ENSG00000076924(gene)|ensembl:ENST00000358368(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0016020"(membrane)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9HCS7|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163 - - comment:"author score: 125" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:zMkadgyIl5RwvoD3h3vetTqLjg49606 rogid:6+Vu8QmYaVK/kd5ADY6uaUY35SQ9606 rigid:ePN9/9kkv7wxoUtWV71kSSRrIwQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P50502 uniprotkb:O75626 intact:EBI-357285|ensembl:ENSP00000216218|uniprotkb:O14999|uniprotkb:Q2TU77 intact:EBI-948789|ensembl:ENSP00000358092|uniprotkb:B2REA6|uniprotkb:E1P5E0|uniprotkb:Q86WM7 psi-mi:f10a1_human(display_long)|uniprotkb:ST13(gene name)|psi-mi:ST13(display_short)|uniprotkb:HIP(gene name synonym)|uniprotkb:SNC6(gene name synonym)|uniprotkb:AAG2(gene name synonym)|uniprotkb:Aging-associated protein 2(gene name synonym)|uniprotkb:FAM10A1(gene name synonym)|uniprotkb:Suppression of tumorigenicity 13 protein(gene name synonym)|uniprotkb:Putative tumor suppressor ST13(gene name synonym)|uniprotkb:Protein FAM10A1(gene name synonym)|uniprotkb:Progesterone receptor-associated p48 protein(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-33(gene name synonym) psi-mi:prdm1_human(display_long)|uniprotkb:PR domain-containing protein 1(gene name synonym)|uniprotkb:Beta-interferon gene positive regulatory domain I-binding factor(gene name synonym)|uniprotkb:BLIMP-1(gene name synonym)|uniprotkb:Positive regulatory domain I-binding factor 1(gene name synonym)|uniprotkb:PRDM1(gene name)|psi-mi:PRDM1(display_short)|uniprotkb:BLIMP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25483036|imex:IM-26985-501 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000100380(gene)|ensembl:ENST00000216218(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0009617"(response to bacterium)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032564"(dATP binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0061084"(negative regulation of protein refolding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR034649|interpro:IPR041243|mint:P50502|rcsb pdb:1UZS|reactome:R-HSA-3371453|refseq:NP_003923.2 ensembl:ENSG00000057657(gene)|ensembl:ENST00000369096(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001763"(morphogenesis of a branching structure)|go:"GO:0001822"(kidney development)|go:"GO:0001893"(maternal placenta development)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003170"(heart valve development)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007281"(germ cell development)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0009791"(post-embryonic development)|interpro:IPR044413|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0032259"(methylation)|go:"GO:0032823"(regulation of natural killer cell differentiation)|go:"GO:0033082"(regulation of extrathymic T cell differentiation)|go:"GO:0035904"(aorta development)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042462"(eye photoreceptor cell development)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045165"(cell fate commitment)|go:"GO:0046872"(metal ion binding)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0051136"(regulation of NK T cell differentiation)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0060707"(trophoblast giant cell differentiation)|go:"GO:0060976"(coronary vasculature development)|go:"GO:1990654"(sebum secreting cell proliferation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR016608(PR-domain zinc finger protein PRDM1)|interpro:IPR036236|rcsb pdb:3DAL|reactome:R-HSA-6804754|mint:O75626|refseq:XP_016866676.1|refseq:NP_001189.2|refseq:XP_011534365.1|refseq:NP_878911.1 - comment:"author score: 24" - figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yqG5t4Kuj7ZzfNwlJzGZYscKiM89606 rogid:Wc1HnBei0Xhkps6Wf65Gjc3nllw9606 rigid:pNhlLZ+bobyO5wQptq07VykBigE false - tandem tag:n-n - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQV5 uniprotkb:Q6P1K8 intact:EBI-12941246|ensembl:ENSP00000435976|uniprotkb:Q8N9F1 intact:EBI-8469755|uniprotkb:A6NED9|uniprotkb:A8K8J6|uniprotkb:B2RCU4|uniprotkb:B7ZW39|intact:MINT-4906733|ensembl:ENSP00000370105|ensembl:ENSP00000422907|ensembl:ENSP00000480471|ensembl:ENSP00000483148 psi-mi:prd11_human(display_long)|uniprotkb:PRDM11(gene name)|psi-mi:PRDM11(display_short)|uniprotkb:PFM8(gene name synonym) psi-mi:t2h2l_human(display_long)|uniprotkb:GTF2H2C(gene name)|psi-mi:GTF2H2C(display_short)|uniprotkb:GTF2H2C_2(gene name)|psi-mi:GTF2H2C_2(display_short)|uniprotkb:GTF2H2D(gene name synonym)|uniprotkb:General transcription factor IIH polypeptide 2-like protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483045|imex:IM-26985-263 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000019485(gene)|ensembl:ENST00000530656(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0032259"(methylation)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2000271"(positive regulation of fibroblast apoptotic process)|interpro:IPR001214(SET)|interpro:IPR044405|mint:Q9NQV5|rcsb pdb:3RAY|refseq:NP_001243624.1|refseq:NP_001243625.1|refseq:XP_011518533.1 refseq:NP_001035955.1|refseq:NP_001092198.1|refseq:XP_005248645.1|refseq:XP_005248647.1|refseq:XP_006714751.1|ensembl:ENSG00000183474(gene)|ensembl:ENSG00000274675(gene)|ensembl:ENST00000380729(transcript)|ensembl:ENST00000510979(transcript)|ensembl:ENST00000619699(transcript)|ensembl:ENST00000621406(transcript)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016607"(nuclear speck)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR004595(TFIIH C1-like, C-terminal)|interpro:IPR007198(Ssl1-like)|interpro:IPR012170(TFIIH basal transcription factor complex, subunit SSL1)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036465|mint:Q6P1K8 - - comment:mint|comment:homomint|comment:"author score: 88" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:++n803wz0/TjJJJu+JVe0WgQrKU9606 rogid:T36j4FIYLk1oSgzWnshu2uW/UbI9606 rigid:JoCKIYczpN+F4+Zd4PxRRAbnzTs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQV5 uniprotkb:P42677 intact:EBI-12941246|ensembl:ENSP00000435976|uniprotkb:Q8N9F1 intact:EBI-356336|ensembl:ENSP00000499044|uniprotkb:Q5T4L6 psi-mi:prd11_human(display_long)|uniprotkb:PRDM11(gene name)|psi-mi:PRDM11(display_short)|uniprotkb:PFM8(gene name synonym) psi-mi:rs27_human(display_long)|uniprotkb:RPS27(gene name)|psi-mi:RPS27(display_short)|uniprotkb:MPS1(gene name synonym)|uniprotkb:Metallopan-stimulin 1(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS27(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483045|imex:IM-26985-263 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000019485(gene)|ensembl:ENST00000530656(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0032259"(methylation)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2000271"(positive regulation of fibroblast apoptotic process)|interpro:IPR001214(SET)|interpro:IPR044405|mint:Q9NQV5|rcsb pdb:3RAY|refseq:NP_001243624.1|refseq:NP_001243625.1|refseq:XP_011518533.1 refseq:NP_001021.1|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|ensembl:ENSG00000177954(gene)|ensembl:ENST00000651669(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|interpro:IPR000592(Ribosomal protein S27e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR023407|mint:P42677|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-141444|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-2467813|reactome:R-HSA-2500257|rcsb pdb:6OM7|reactome:R-HSA-5663220|reactome:R-HSA-6791226|reactome:R-HSA-68877|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-9648025|reactome:R-HSA-975956|reactome:R-HSA-975957|dip:DIP-44182N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:++n803wz0/TjJJJu+JVe0WgQrKU9606 rogid:OA5IWAJDBpY5FFdVnun7Sq/jI7g9606 rigid:JoCKIYczpN+F4+Zd4PxRRAbnzTs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQV5 uniprotkb:P24666 intact:EBI-12941246|ensembl:ENSP00000435976|uniprotkb:Q8N9F1 intact:EBI-717701|uniprotkb:P24667|uniprotkb:Q16035|uniprotkb:Q53RU0|uniprotkb:Q16036|uniprotkb:Q16725|uniprotkb:Q3KQX8|uniprotkb:A8K1L9|uniprotkb:B5MCC7|ensembl:ENSP00000272065 psi-mi:prd11_human(display_long)|uniprotkb:PRDM11(gene name)|psi-mi:PRDM11(display_short)|uniprotkb:PFM8(gene name synonym) psi-mi:ppac_human(display_long)|uniprotkb:Low molecular weight cytosolic acid phosphatase(gene name synonym)|uniprotkb:Red cell acid phosphatase 1(gene name synonym)|uniprotkb:Adipocyte acid phosphatase(gene name synonym)|uniprotkb:ACP1(gene name)|psi-mi:ACP1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483045|imex:IM-26985-263 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000019485(gene)|ensembl:ENST00000530656(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0032259"(methylation)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2000271"(positive regulation of fibroblast apoptotic process)|interpro:IPR001214(SET)|interpro:IPR044405|mint:Q9NQV5|rcsb pdb:3RAY|refseq:NP_001243624.1|refseq:NP_001243625.1|refseq:XP_011518533.1 refseq:NP_004291.1|refseq:NP_009030.1|ensembl:ENSG00000143727(gene)|ensembl:ENST00000272065(transcript)|go:"GO:0003993"(acid phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0004726"(non-membrane spanning protein tyrosine phosphatase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0042383"(sarcolemma)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002115(Protein-tyrosine phosphatase, low molecular weight, mammalian)|interpro:IPR017867|interpro:IPR023485|interpro:IPR036196|mint:P24666|rcsb pdb:1XWW|rcsb pdb:3N8I|rcsb pdb:4Z99|rcsb pdb:4Z9A|rcsb pdb:4Z9B|rcsb pdb:5JNR|rcsb pdb:5JNS|rcsb pdb:5JNT|rcsb pdb:5KQG|rcsb pdb:5KQL|rcsb pdb:5KQM|rcsb pdb:5KQP|rcsb pdb:5PNT|rcsb pdb:6Y2V|rcsb pdb:6Y2W|rcsb pdb:7KH8 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:++n803wz0/TjJJJu+JVe0WgQrKU9606 rogid:j4VyGaaWO8l/Ah8i1HBU6EnbK289606 rigid:JoCKIYczpN+F4+Zd4PxRRAbnzTs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQV5 uniprotkb:Q5T1J5 intact:EBI-12941246|ensembl:ENSP00000435976|uniprotkb:Q8N9F1 intact:EBI-5325274 psi-mi:prd11_human(display_long)|uniprotkb:PRDM11(gene name)|psi-mi:PRDM11(display_short)|uniprotkb:PFM8(gene name synonym) psi-mi:chch9_human(display_long)|uniprotkb:CHCHD2P9(gene name)|psi-mi:CHCHD2P9(display_short)|uniprotkb:C9orf49(gene name synonym)|uniprotkb:CHCHD9(gene name synonym)|uniprotkb:Coiled-coil-helix-coiled-coil-helix domain-containing 2 pseudogene 9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483045|imex:IM-26985-263 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000019485(gene)|ensembl:ENST00000530656(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0032259"(methylation)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2000271"(positive regulation of fibroblast apoptotic process)|interpro:IPR001214(SET)|interpro:IPR044405|mint:Q9NQV5|rcsb pdb:3RAY|refseq:NP_001243624.1|refseq:NP_001243625.1|refseq:XP_011518533.1 go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|mint:Q5T1J5 - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:++n803wz0/TjJJJu+JVe0WgQrKU9606 rogid:nxLtnxxMIGeGK2oC3BIhcwkacSs9606 rigid:JoCKIYczpN+F4+Zd4PxRRAbnzTs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQV5 uniprotkb:P55345 intact:EBI-12941246|ensembl:ENSP00000435976|uniprotkb:Q8N9F1 intact:EBI-78458|uniprotkb:P78350|uniprotkb:Q9BW15|uniprotkb:Q9UMC2|ensembl:ENSP00000347906|ensembl:ENSP00000380759|ensembl:ENSP00000380760|uniprotkb:Q6FHF0|uniprotkb:Q99781|uniprotkb:Q498Y5|uniprotkb:B7U630|uniprotkb:B7U631|uniprotkb:B7U632|uniprotkb:Q5U7D4 psi-mi:prd11_human(display_long)|uniprotkb:PRDM11(gene name)|psi-mi:PRDM11(display_short)|uniprotkb:PFM8(gene name synonym) psi-mi:anm2_human(display_long)|uniprotkb:PRMT2(gene name)|psi-mi:PRMT2(display_short)|uniprotkb:HMT1(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT2(gene name synonym)|uniprotkb:HRMT1L1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483045|imex:IM-26985-263 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000019485(gene)|ensembl:ENST00000530656(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0032259"(methylation)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2000271"(positive regulation of fibroblast apoptotic process)|interpro:IPR001214(SET)|interpro:IPR044405|mint:Q9NQV5|rcsb pdb:3RAY|refseq:NP_001243624.1|refseq:NP_001243625.1|refseq:XP_011518533.1 ensembl:ENSG00000160310(gene)|ensembl:ENST00000355680(transcript)|ensembl:ENST00000397637(transcript)|ensembl:ENST00000397638(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048588"(developmental cell growth)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001452(Src homology-3)|interpro:IPR007848(Methyltransferase small)|interpro:IPR025799|interpro:IPR029063|interpro:IPR036028|mint:P55345|rcsb pdb:1X2P|refseq:NP_001526.2|refseq:NP_996845.1|refseq:NP_001273605.1|refseq:NP_001273606.1|refseq:NP_001273607.1|refseq:NP_001229794.1|refseq:NP_001229793.1|refseq:XP_005261168.1|refseq:NP_001229795.1|refseq:XP_006724061.1|refseq:XP_006724063.1 - - comment:"author score: 41" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:++n803wz0/TjJJJu+JVe0WgQrKU9606 rogid:+xna8Cy+5sQWV6hvKfg4rNrQKBw9606 rigid:JoCKIYczpN+F4+Zd4PxRRAbnzTs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQV5 uniprotkb:Q92759 intact:EBI-12941246|ensembl:ENSP00000435976|uniprotkb:Q8N9F1 intact:EBI-6380495|ensembl:ENSP00000259895|ensembl:ENSP00000365493|ensembl:ENSP00000365504|ensembl:ENSP00000383300|ensembl:ENSP00000387980|ensembl:ENSP00000388227|ensembl:ENSP00000395497|ensembl:ENSP00000396251|ensembl:ENSP00000399554|ensembl:ENSP00000401105|ensembl:ENSP00000403156|ensembl:ENSP00000409483|uniprotkb:Q76KU4|uniprotkb:B4DTJ5 psi-mi:prd11_human(display_long)|uniprotkb:PRDM11(gene name)|psi-mi:PRDM11(display_short)|uniprotkb:PFM8(gene name synonym) psi-mi:tf2h4_human(display_long)|uniprotkb:GTF2H4(gene name)|psi-mi:GTF2H4(display_short)|uniprotkb:Basic transcription factor 2 52 kDa subunit(gene name synonym)|uniprotkb:General transcription factor IIH polypeptide 4(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p52 subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483045|imex:IM-26985-263 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000019485(gene)|ensembl:ENST00000530656(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0032259"(methylation)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2000271"(positive regulation of fibroblast apoptotic process)|interpro:IPR001214(SET)|interpro:IPR044405|mint:Q9NQV5|rcsb pdb:3RAY|refseq:NP_001243624.1|refseq:NP_001243625.1|refseq:XP_011518533.1 rcsb pdb:5OF4|rcsb pdb:6NMI|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:6RO4|reactome:R-HSA-167158|rcsb pdb:7EGB|reactome:R-HSA-167160|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|reactome:R-HSA-167161|rcsb pdb:7NVR|rcsb pdb:7NVV|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-72086|reactome:R-HSA-73762|rcsb pdb:7NVW|reactome:R-HSA-73772|rcsb pdb:7NVX|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|rcsb pdb:7NVY|reactome:R-HSA-77075|rcsb pdb:7NVZ|ensembl:ENSG00000213780(gene)|ensembl:ENSG00000221974(gene)|ensembl:ENSG00000226384(gene)|ensembl:ENSG00000233149(gene)|ensembl:ENSG00000234370(gene)|ensembl:ENSG00000236895(gene)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|ensembl:ENST00000259895(transcript)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0016607"(nuclear speck)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR004598(Transcription factor Tfb2)|interpro:IPR040662|mint:Q92759|rcsb pdb:5IVW|rcsb pdb:5IY6|rcsb pdb:5IY7|ensembl:ENST00000376316(transcript)|ensembl:ENST00000376326(transcript)|rcsb pdb:5IY8|ensembl:ENST00000400450(transcript)|ensembl:ENST00000413314(transcript)|rcsb pdb:5IY9|ensembl:ENST00000416773(transcript)|ensembl:ENST00000423881(transcript)|ensembl:ENST00000434226(transcript)|ensembl:ENST00000435498(transcript)|ensembl:ENST00000438348(transcript)|ensembl:ENST00000440824(transcript)|ensembl:ENST00000456968(transcript)|go:"GO:0000438"(core TFIIH complex portion of holo TFIIH complex)|dip:DIP-48376N|refseq:NP_001508.1 - - comment:"author score: 58" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:++n803wz0/TjJJJu+JVe0WgQrKU9606 rogid:vQJkQt6yfTyMyQ6oYP1HpNv7hlY9606 rigid:JoCKIYczpN+F4+Zd4PxRRAbnzTs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQV5 uniprotkb:P32780 intact:EBI-12941246|ensembl:ENSP00000435976|uniprotkb:Q8N9F1 intact:EBI-715539|uniprotkb:Q9H5K5|uniprotkb:Q9NQD9|uniprotkb:Q6I9Y7|uniprotkb:B3KXE0|uniprotkb:D3DQY2|ensembl:ENSP00000265963|ensembl:ENSP00000393638|ensembl:ENSP00000500178|ensembl:ENSP00000500852 psi-mi:prd11_human(display_long)|uniprotkb:PRDM11(gene name)|psi-mi:PRDM11(display_short)|uniprotkb:PFM8(gene name synonym) psi-mi:tf2h1_human(display_long)|uniprotkb:General transcription factor IIH polypeptide 1(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p62 subunit(gene name synonym)|uniprotkb:Basic transcription factor 2 62 kDa subunit(gene name synonym)|uniprotkb:GTF2H1(gene name)|psi-mi:GTF2H1(display_short)|uniprotkb:BTF2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483045|imex:IM-26985-263 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000019485(gene)|ensembl:ENST00000530656(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0032259"(methylation)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2000271"(positive regulation of fibroblast apoptotic process)|interpro:IPR001214(SET)|interpro:IPR044405|mint:Q9NQV5|rcsb pdb:3RAY|refseq:NP_001243624.1|refseq:NP_001243625.1|refseq:XP_011518533.1 refseq:NP_001135779.1|refseq:NP_005307.1|ensembl:ENSG00000110768(gene)|ensembl:ENSG00000288114(gene)|ensembl:ENST00000265963(transcript)|ensembl:ENST00000453096(transcript)|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|ensembl:ENST00000672827(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0009755"(hormone-mediated signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR005607(BSD)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013876(TFIIH p62 subunit, N-terminal)|interpro:IPR027079|interpro:IPR035925|mint:P32780|rcsb pdb:1PFJ|rcsb pdb:2DII|rcsb pdb:2RNR|rcsb pdb:2RUK|rcsb pdb:2RVB|rcsb pdb:5GOW|rcsb pdb:5XV8|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:7BUL|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|ensembl:ENST00000672527(transcript)|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|refseq:XP_006718271.1|dip:DIP-708N - - comment:"author score: 59" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:++n803wz0/TjJJJu+JVe0WgQrKU9606 rogid:X5tWUeZYcYgB31HZSn8Ndi9w3V89606 rigid:JoCKIYczpN+F4+Zd4PxRRAbnzTs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQV5 uniprotkb:P35269 intact:EBI-12941246|ensembl:ENSP00000435976|uniprotkb:Q8N9F1 intact:EBI-457886|uniprotkb:Q9BWN0|ensembl:ENSP00000377969|uniprotkb:B2RCS0 psi-mi:prd11_human(display_long)|uniprotkb:PRDM11(gene name)|psi-mi:PRDM11(display_short)|uniprotkb:PFM8(gene name synonym) psi-mi:t2fa_human(display_long)|uniprotkb:Transcription initiation factor IIF subunit alpha(gene name synonym)|uniprotkb:GTF2F1(gene name)|psi-mi:GTF2F1(display_short)|uniprotkb:RAP74(gene name synonym)|uniprotkb:Transcription initiation factor RAP74(gene name synonym)|uniprotkb:General transcription factor IIF 74 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483045|imex:IM-26985-263 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000019485(gene)|ensembl:ENST00000530656(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0032259"(methylation)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2000271"(positive regulation of fibroblast apoptotic process)|interpro:IPR001214(SET)|interpro:IPR044405|mint:Q9NQV5|rcsb pdb:3RAY|refseq:NP_001243624.1|refseq:NP_001243625.1|refseq:XP_011518533.1 go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR008851(Transcription initiation factor IIF, alpha subunit)|interpro:IPR011039(Transcription Factor IIF, Rap30/Rap74, interaction)|interpro:IPR036388|interpro:IPR036390|mint:P35269|rcsb pdb:1F3U|rcsb pdb:1I27|rcsb pdb:1J2X|rcsb pdb:1NHA|rcsb pdb:1ONV|rcsb pdb:2K7L|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009615"(response to virus)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|rcsb pdb:6O9L|refseq:NP_002087.2|go:"GO:0001096"(TFIIF-class transcription factor complex binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005674"(transcription factor TFIIF complex)|go:"GO:0006366"(transcription by RNA polymerase II)|ensembl:ENSG00000125651(gene)|ensembl:ENST00000394456(transcript)|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|rcsb pdb:7EDX|rcsb pdb:7EG7|rcsb pdb:7EG8|rcsb pdb:7EG9|rcsb pdb:7EGA|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVS|rcsb pdb:7NVT|rcsb pdb:7NVU|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|dip:DIP-677N - - comment:"author score: 73" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:++n803wz0/TjJJJu+JVe0WgQrKU9606 rogid:UHTMke+O4hI3MIvpMB6opKwV3Go9606 rigid:JoCKIYczpN+F4+Zd4PxRRAbnzTs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQV5 uniprotkb:P19447 intact:EBI-12941246|ensembl:ENSP00000435976|uniprotkb:Q8N9F1 intact:EBI-1183307|uniprotkb:Q53QM0|ensembl:ENSP00000285398 psi-mi:prd11_human(display_long)|uniprotkb:PRDM11(gene name)|psi-mi:PRDM11(display_short)|uniprotkb:PFM8(gene name synonym) psi-mi:ercc3_human(display_long)|uniprotkb:ERCC3(gene name)|psi-mi:ERCC3(display_short)|uniprotkb:XPB(gene name synonym)|uniprotkb:XPBC(gene name synonym)|uniprotkb:Basic transcription factor 2 89 kDa subunit(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex 89 kDa subunit(gene name synonym)|uniprotkb:DNA repair protein complementing XP-B cells(gene name synonym)|uniprotkb:Xeroderma pigmentosum group B-complementing protein(gene name synonym)|uniprotkb:DNA excision repair protein ERCC-3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483045|imex:IM-26985-263 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000019485(gene)|ensembl:ENST00000530656(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0032259"(methylation)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2000271"(positive regulation of fibroblast apoptotic process)|interpro:IPR001214(SET)|interpro:IPR044405|mint:Q9NQV5|rcsb pdb:3RAY|refseq:NP_001243624.1|refseq:NP_001243625.1|refseq:XP_011518533.1 refseq:NP_000113.1|ensembl:ENSG00000163161(gene)|ensembl:ENST00000285398(transcript)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0000717"(nucleotide-excision repair, DNA duplex unwinding)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006265"(DNA topological change)|go:"GO:0006281"(DNA repair)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006362"(transcription elongation from RNA polymerase I promoter)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006915"(apoptotic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0009411"(response to UV)|go:"GO:0009650"(UV protection)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0033683"(nucleotide-excision repair, DNA incision)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048568"(embryonic organ development)|go:"GO:0097550"(transcription preinitiation complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001161("Xeroderma pigmentosum group B protein (XP-B)")|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006935(Restriction endonuclease, type I, R subunit/Type III, Res subunit)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR032438|interpro:IPR032830|mint:P19447|rcsb pdb:4ERN|rcsb pdb:5IVW|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5OF4|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:6RO4|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVV|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|go:"GO:0000112"(nucleotide-excision repair factor 3 complex)|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-73863|dip:DIP-83N - - comment:"author score: 77" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:++n803wz0/TjJJJu+JVe0WgQrKU9606 rogid:KOM9+f636LHK8qfTFkLIm0X0VoY9606 rigid:JoCKIYczpN+F4+Zd4PxRRAbnzTs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQV5 uniprotkb:Q13889 intact:EBI-12941246|ensembl:ENSP00000435976|uniprotkb:Q8N9F1 intact:EBI-6380459|uniprotkb:B4DNZ6|ensembl:ENSP00000445162|uniprotkb:B2R819|uniprotkb:Q7L0G0|uniprotkb:Q96AT7 psi-mi:prd11_human(display_long)|uniprotkb:PRDM11(gene name)|psi-mi:PRDM11(display_short)|uniprotkb:PFM8(gene name synonym) psi-mi:tf2h3_human(display_long)|uniprotkb:GTF2H3(gene name)|psi-mi:GTF2H3(display_short)|uniprotkb:Basic transcription factor 2 34 kDa subunit(gene name synonym)|uniprotkb:General transcription factor IIH polypeptide 3(gene name synonym)|uniprotkb:TFIIH basal transcription factor complex p34 subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483045|imex:IM-26985-263 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000019485(gene)|ensembl:ENST00000530656(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0032259"(methylation)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:2000271"(positive regulation of fibroblast apoptotic process)|interpro:IPR001214(SET)|interpro:IPR044405|mint:Q9NQV5|rcsb pdb:3RAY|refseq:NP_001243624.1|refseq:NP_001243625.1|refseq:XP_011518533.1 ensembl:ENSG00000111358(gene)|ensembl:ENST00000543341(transcript)|go:"GO:0000438"(core TFIIH complex portion of holo TFIIH complex)|go:"GO:0000439"(transcription factor TFIIH core complex)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005669"(transcription factor TFIID complex)|go:"GO:0005675"(transcription factor TFIIH holo complex)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0016251"(RNA polymerase II general transcription initiation factor activity)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070816"(phosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0097550"(transcription preinitiation complex)|interpro:IPR004600(Transcription factor Tfb4)|interpro:IPR036465|mint:Q13889|rcsb pdb:5IVW|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5O85|rcsb pdb:5OF4|rcsb pdb:6NMI|rcsb pdb:6O9L|rcsb pdb:6O9M|rcsb pdb:6RO4|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7LBM|rcsb pdb:7NVR|rcsb pdb:7NVW|rcsb pdb:7NVX|rcsb pdb:7NVY|rcsb pdb:7NVZ|rcsb pdb:7NW0|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167246|reactome:R-HSA-427413|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-72086|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73863|reactome:R-HSA-75953|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-75955|dip:DIP-787N|refseq:NP_001258795.1|refseq:NP_001258796.1|refseq:NP_001258797.1|refseq:NP_001507.2 - - comment:"author score: 141" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:++n803wz0/TjJJJu+JVe0WgQrKU9606 rogid:Ca5tFYnStJdHF1eNPEwLZtKB0+09606 rigid:JoCKIYczpN+F4+Zd4PxRRAbnzTs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H4Q3 uniprotkb:O60814 intact:EBI-20833301|ensembl:ENSP00000358217|uniprotkb:Q5TGC1|uniprotkb:Q5TGC2 intact:EBI-4409738|uniprotkb:A8K7P7|uniprotkb:Q2VPI7|ensembl:ENSP00000349430 psi-mi:prd13_human(display_long)|uniprotkb:PR domain-containing protein 13(gene name synonym)|uniprotkb:PRDM13(gene name)|psi-mi:PRDM13(display_short)|uniprotkb:PFM10(gene name synonym) psi-mi:h2b1k_human(display_long)|uniprotkb:H2BC12(gene name)|psi-mi:H2BC12(display_short)|uniprotkb:H2BFT(gene name synonym)|uniprotkb:HIRA-interacting protein 1(gene name synonym)|uniprotkb:HIRIP1(gene name synonym)|uniprotkb:HIST1H2BK(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483081|imex:IM-26985-345 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000112238(gene)|ensembl:ENST00000369215(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0032259"(methylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044407|mint:Q9H4Q3|refseq:NP_067633.2 refseq:NP_542160.1|refseq:NP_001299582.1|dip:DIP-48935N|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|ensembl:ENSG00000197903(gene)|ensembl:ENST00000356950(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:O60814|rcsb pdb:2CV5|rcsb pdb:6KE9|rcsb pdb:6L9H|rcsb pdb:6LE9|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6V92|rcsb pdb:6Y5D|rcsb pdb:7BWD|rcsb pdb:7DBP|rcsb pdb:7JZV|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:sajk2ZFdCR+sxkeEtBzYoQxx7Ps9606 rogid:aBHcFUkMIdiiZov716H7kxmHzj09606 rigid:ipMrIXhvqd329d+tFXIlCQa2GrE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H4Q3 uniprotkb:O75688 intact:EBI-20833301|ensembl:ENSP00000358217|uniprotkb:Q5TGC1|uniprotkb:Q5TGC2 intact:EBI-1047039|uniprotkb:Q9HAY8|uniprotkb:Q461Q2|uniprotkb:Q658R4|ensembl:ENSP00000282412|uniprotkb:Q96ER6|uniprotkb:Q4J6C1|uniprotkb:Q4J6C2 psi-mi:prd13_human(display_long)|uniprotkb:PR domain-containing protein 13(gene name synonym)|uniprotkb:PRDM13(gene name)|psi-mi:PRDM13(display_short)|uniprotkb:PFM10(gene name synonym) psi-mi:ppm1b_human(display_long)|uniprotkb:Protein phosphatase 2C isoform beta(gene name synonym)|uniprotkb:PPM1B(gene name)|psi-mi:PPM1B(display_short)|uniprotkb:PP2CB(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483081|imex:IM-26985-345 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000112238(gene)|ensembl:ENST00000369215(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0032259"(methylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044407|mint:Q9H4Q3|refseq:NP_067633.2 refseq:NP_001028729.1|refseq:NP_002697.1|refseq:NP_808907.1|refseq:NP_808908.1|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|interpro:IPR000222(Protein phosphatase 2C, manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR012911(Protein serine/threonine phosphatase 2C, C-terminal)|interpro:IPR036457|interpro:IPR036580|mint:O75688|rcsb pdb:2P8E|reactome:R-HSA-1169408|ensembl:ENSG00000138032(gene)|ensembl:ENST00000282412(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006499"(N-terminal protein myristoylation)|go:"GO:0016020"(membrane)|go:"GO:0030145"(manganese ion binding)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0035970"(peptidyl-threonine dephosphorylation) - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:sajk2ZFdCR+sxkeEtBzYoQxx7Ps9606 rogid:cwwfGSSTv9pR/XNLa9UxQ/6hpD89606 rigid:ipMrIXhvqd329d+tFXIlCQa2GrE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H4Q3 uniprotkb:P62805 intact:EBI-20833301|ensembl:ENSP00000358217|uniprotkb:Q5TGC1|uniprotkb:Q5TGC2 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:prd13_human(display_long)|uniprotkb:PR domain-containing protein 13(gene name synonym)|uniprotkb:PRDM13(gene name)|psi-mi:PRDM13(display_short)|uniprotkb:PFM10(gene name synonym) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483081|imex:IM-26985-345 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000112238(gene)|ensembl:ENST00000369215(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0032259"(methylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044407|mint:Q9H4Q3|refseq:NP_067633.2 ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:sajk2ZFdCR+sxkeEtBzYoQxx7Ps9606 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 rigid:ipMrIXhvqd329d+tFXIlCQa2GrE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H4Q3 uniprotkb:P04908 intact:EBI-20833301|ensembl:ENSP00000358217|uniprotkb:Q5TGC1|uniprotkb:Q5TGC2 intact:EBI-358971|uniprotkb:Q76P63|uniprotkb:P28001|ensembl:ENSP00000303373|ensembl:ENSP00000483842 psi-mi:prd13_human(display_long)|uniprotkb:PR domain-containing protein 13(gene name synonym)|uniprotkb:PRDM13(gene name)|psi-mi:PRDM13(display_short)|uniprotkb:PFM10(gene name synonym) psi-mi:h2a1b_human(display_long)|uniprotkb:H2AC4(gene name)|psi-mi:H2AC4(display_short)|uniprotkb:H2AC8(gene name)|psi-mi:H2AC8(display_short)|uniprotkb:H2AFA(gene name synonym)|uniprotkb:H2AFM(gene name synonym)|uniprotkb:HIST1H2AB(gene name synonym)|uniprotkb:HIST1H2AE(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/a(gene name synonym)|uniprotkb:Histone H2A/m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483081|imex:IM-26985-345 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000112238(gene)|ensembl:ENST00000369215(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0032259"(methylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044407|mint:Q9H4Q3|refseq:NP_067633.2 refseq:NP_003504.2|refseq:NP_066390.1|ensembl:ENSG00000277075(gene)|ensembl:ENSG00000278463(gene)|ensembl:ENST00000303910(transcript)|ensembl:ENST00000615868(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P04908|rcsb pdb:2CV5|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1V|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACL|rcsb pdb:6AEE|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6KE9|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V92|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|rcsb pdb:6JXD|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|dip:DIP-44197N - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:sajk2ZFdCR+sxkeEtBzYoQxx7Ps9606 rogid:4Qno1mMYZB6FdNoojrzulWLVq849606 rigid:ipMrIXhvqd329d+tFXIlCQa2GrE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H4Q3 uniprotkb:P16403 intact:EBI-20833301|ensembl:ENSP00000358217|uniprotkb:Q5TGC1|uniprotkb:Q5TGC2 intact:EBI-358372|ensembl:ENSP00000339566|uniprotkb:A8K4I2 psi-mi:prd13_human(display_long)|uniprotkb:PR domain-containing protein 13(gene name synonym)|uniprotkb:PRDM13(gene name)|psi-mi:PRDM13(display_short)|uniprotkb:PFM10(gene name synonym) psi-mi:h12_human(display_long)|uniprotkb:H1-2(gene name)|psi-mi:H1-2(display_short)|uniprotkb:H1F2(gene name synonym)|uniprotkb:HIST1H1C(gene name synonym)|uniprotkb:Histone H1c(gene name synonym)|uniprotkb:Histone H1d(gene name synonym)|uniprotkb:Histone H1s-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483081|imex:IM-26985-345 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000112238(gene)|ensembl:ENST00000369215(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0032259"(methylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044407|mint:Q9H4Q3|refseq:NP_067633.2 refseq:NP_005310.1|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P16403|reactome:R-HSA-140342|reactome:R-HSA-2559584|ensembl:ENSG00000187837(gene)|ensembl:ENST00000343677(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|dip:DIP-36359N - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:sajk2ZFdCR+sxkeEtBzYoQxx7Ps9606 rogid:eRT5bTyBJUg6nRANMRYZekT4N+g9606 rigid:ipMrIXhvqd329d+tFXIlCQa2GrE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H4Q3 uniprotkb:P23588 intact:EBI-20833301|ensembl:ENSP00000358217|uniprotkb:Q5TGC1|uniprotkb:Q5TGC2 intact:EBI-970310|ensembl:ENSP00000262056|uniprotkb:Q4G0E3|uniprotkb:Q53HQ2|uniprotkb:Q6GPH5|uniprotkb:Q6IB46|uniprotkb:Q8WYK5|uniprotkb:B4DS13 psi-mi:prd13_human(display_long)|uniprotkb:PR domain-containing protein 13(gene name synonym)|uniprotkb:PRDM13(gene name)|psi-mi:PRDM13(display_short)|uniprotkb:PFM10(gene name synonym) psi-mi:if4b_human(display_long)|uniprotkb:EIF4B(gene name)|psi-mi:EIF4B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483081|imex:IM-26985-345 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000112238(gene)|ensembl:ENST00000369215(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0032259"(methylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044407|mint:Q9H4Q3|refseq:NP_067633.2 ensembl:ENSG00000063046(gene)|ensembl:ENST00000262056(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0030425"(dendrite)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034057"(RNA strand-exchange activity)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0097010"(eukaryotic translation initiation factor 4F complex assembly)|go:"GO:0098794"(postsynapse)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033107|interpro:IPR035979|mint:P23588|rcsb pdb:1WI8|rcsb pdb:2J76|rcsb pdb:6FEC|reactome:R-HSA-156827|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_001408.2|refseq:NP_001317583.1 - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:sajk2ZFdCR+sxkeEtBzYoQxx7Ps9606 rogid:6QlRkSj6suC5apkUxdZhOq+OMBc9606 rigid:ipMrIXhvqd329d+tFXIlCQa2GrE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H4Q3 uniprotkb:P68363 intact:EBI-20833301|ensembl:ENSP00000358217|uniprotkb:Q5TGC1|uniprotkb:Q5TGC2 intact:EBI-487083|intact:EBI-1384226|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:Q27I68|ensembl:ENSP00000336799|uniprotkb:Q8WU19 psi-mi:prd13_human(display_long)|uniprotkb:PR domain-containing protein 13(gene name synonym)|uniprotkb:PRDM13(gene name)|psi-mi:PRDM13(display_short)|uniprotkb:PFM10(gene name synonym) psi-mi:tba1b_human(display_long)|uniprotkb:TUBA1B(gene name)|psi-mi:TUBA1B(display_short)|uniprotkb:Tubulin alpha-ubiquitous chain(gene name synonym)|uniprotkb:Alpha-tubulin ubiquitous(gene name synonym)|uniprotkb:Tubulin K-alpha-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483081|imex:IM-26985-345 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000112238(gene)|ensembl:ENST00000369215(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0032259"(methylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044407|mint:Q9H4Q3|refseq:NP_067633.2 refseq:NP_006073.2|ensembl:ENSG00000123416(gene)|ensembl:ENST00000336023(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-983189|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|go:"GO:0045121"(membrane raft)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68363|rcsb pdb:2E4H|rcsb pdb:5IJ0|rcsb pdb:5IJ9|rcsb pdb:5N5N|rcsb pdb:6E7B|rcsb pdb:6E7C|rcsb pdb:6I2I|go:"GO:0051301"(cell division)|rcsb pdb:6J4V|rcsb pdb:6J8O|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|rcsb pdb:6S8L|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9013407|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-2132295|reactome:R-HSA-9668328 - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:sajk2ZFdCR+sxkeEtBzYoQxx7Ps9606 rogid:D4YpuLCXl/S+53qV7P7sF81aARY9606 rigid:ipMrIXhvqd329d+tFXIlCQa2GrE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HAZ2 uniprotkb:Q9BQE3 intact:EBI-2795620|uniprotkb:A6NHQ8|uniprotkb:B1AJP7|uniprotkb:B1AJP8|uniprotkb:B1AJP9|uniprotkb:B1WB48|uniprotkb:Q8WYJ9|uniprotkb:Q9C0I8|ensembl:ENSP00000270722 intact:EBI-1103245|ensembl:ENSP00000301072 psi-mi:prd16_human(display_long)|uniprotkb:PRDM16(gene name)|psi-mi:PRDM16(display_short)|uniprotkb:KIAA1675(gene name synonym)|uniprotkb:MEL1(gene name synonym)|uniprotkb:PFM13(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym)|uniprotkb:PR domain zinc finger protein 16(gene name synonym) psi-mi:tba1c_human(display_long)|uniprotkb:TUBA1C(gene name)|psi-mi:TUBA1C(display_short)|uniprotkb:TUBA6(gene name synonym)|uniprotkb:Tubulin alpha-6 chain(gene name synonym)|uniprotkb:Alpha-tubulin 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483108|imex:IM-26985-347 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540247.1|refseq:NP_071397.3|refseq:NP_955533.2|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:Q9HAZ2|rcsb pdb:2N1I|rcsb pdb:6BW4|reactome:R-HSA-3214841|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|ensembl:ENSG00000142611(gene)|ensembl:ENST00000270722(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0003712"(transcription coregulator activity) reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|ensembl:ENSG00000167553(gene)|ensembl:ENST00000301072(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031982"(vesicle)|go:"GO:0051301"(cell division)|interpro:IPR000217(Tubulin)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:Q9BQE3|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-9668328|reactome:R-HSA-983189|refseq:NP_116093.1 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:1adjB6FTm5Cp3QK0QQK2Iwmkk809606 rogid:53r1CNUJNgCreVCw4riUsTPh+yw9606 rigid:jg1/GgBhsIdyHcjbvmFbzJ/6u+s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HAZ2 uniprotkb:P62854 intact:EBI-2795620|uniprotkb:A6NHQ8|uniprotkb:B1AJP7|uniprotkb:B1AJP8|uniprotkb:B1AJP9|uniprotkb:B1WB48|uniprotkb:Q8WYJ9|uniprotkb:Q9C0I8|ensembl:ENSP00000270722 intact:EBI-353438|uniprotkb:P02383|uniprotkb:Q3MHD8|uniprotkb:P70394|uniprotkb:Q06722|uniprotkb:Q6IRY4|ensembl:ENSP00000348849|ensembl:ENSP00000450339|ensembl:ENSP00000496643 psi-mi:prd16_human(display_long)|uniprotkb:PRDM16(gene name)|psi-mi:PRDM16(display_short)|uniprotkb:KIAA1675(gene name synonym)|uniprotkb:MEL1(gene name synonym)|uniprotkb:PFM13(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym)|uniprotkb:PR domain zinc finger protein 16(gene name synonym) psi-mi:rs26_human(display_long)|uniprotkb:RPS26(gene name)|psi-mi:RPS26(display_short)|uniprotkb:Small ribosomal subunit protein eS26(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483108|imex:IM-26985-347 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540247.1|refseq:NP_071397.3|refseq:NP_955533.2|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:Q9HAZ2|rcsb pdb:2N1I|rcsb pdb:6BW4|reactome:R-HSA-3214841|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|ensembl:ENSG00000142611(gene)|ensembl:ENST00000270722(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_001020.2|refseq:XP_005276741.1|rcsb pdb:6OLG|rcsb pdb:6OLF|ensembl:ENST00000356464(transcript)|ensembl:ENST00000552361(transcript)|ensembl:ENST00000646449(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|interpro:IPR000892(Ribosomal protein S26e)|interpro:IPR038551|mint:P62854|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6G5H|ensembl:ENSG00000197728(gene)|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-156827 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:1adjB6FTm5Cp3QK0QQK2Iwmkk809606 rogid:bo2ruYMNjjLCMo/kwAWzmlJrrjU9606 rigid:jg1/GgBhsIdyHcjbvmFbzJ/6u+s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HAZ2 uniprotkb:Q9HCY8 intact:EBI-2795620|uniprotkb:A6NHQ8|uniprotkb:B1AJP7|uniprotkb:B1AJP8|uniprotkb:B1AJP9|uniprotkb:B1WB48|uniprotkb:Q8WYJ9|uniprotkb:Q9C0I8|ensembl:ENSP00000270722 intact:EBI-751842|uniprotkb:Q5RHT0|ensembl:ENSP00000340463|ensembl:ENSP00000357690|ensembl:ENSP00000357691|ensembl:ENSP00000420296 psi-mi:prd16_human(display_long)|uniprotkb:PRDM16(gene name)|psi-mi:PRDM16(display_short)|uniprotkb:KIAA1675(gene name synonym)|uniprotkb:MEL1(gene name synonym)|uniprotkb:PFM13(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym)|uniprotkb:PR domain zinc finger protein 16(gene name synonym) psi-mi:s10ae_human(display_long)|uniprotkb:S100 calcium-binding protein A14(gene name synonym)|uniprotkb:S100A14(gene name)|psi-mi:S100A14(display_short)|uniprotkb:S100A15(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483108|imex:IM-26985-347 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540247.1|refseq:NP_071397.3|refseq:NP_955533.2|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:Q9HAZ2|rcsb pdb:2N1I|rcsb pdb:6BW4|reactome:R-HSA-3214841|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|ensembl:ENSG00000142611(gene)|ensembl:ENST00000270722(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_065723.1|refseq:XP_005245419.1|refseq:XP_016857364.1|ensembl:ENSG00000189334(gene)|ensembl:ENST00000344616(transcript)|ensembl:ENST00000368701(transcript)|ensembl:ENST00000368702(transcript)|ensembl:ENST00000476873(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0006915"(apoptotic process)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0042379"(chemokine receptor binding)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071624"(positive regulation of granulocyte chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028493|mint:Q9HCY8|rcsb pdb:2M0R - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:1adjB6FTm5Cp3QK0QQK2Iwmkk809606 rogid:8XSIQKZSb+jAmTmawRUTHjcGwb49606 rigid:jg1/GgBhsIdyHcjbvmFbzJ/6u+s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HAZ2 uniprotkb:Q9UGM3 intact:EBI-2795620|uniprotkb:A6NHQ8|uniprotkb:B1AJP7|uniprotkb:B1AJP8|uniprotkb:B1AJP9|uniprotkb:B1WB48|uniprotkb:Q8WYJ9|uniprotkb:Q9C0I8|ensembl:ENSP00000270722 intact:EBI-1044970|uniprotkb:Q59EX0|uniprotkb:Q5JR26|uniprotkb:Q6MZN4|uniprotkb:Q96DU4|uniprotkb:Q9UGM2|uniprotkb:Q9UJ57|uniprotkb:Q9UKJ4|uniprotkb:Q9Y211|uniprotkb:Q9Y4V9|uniprotkb:A6NDG4|uniprotkb:A6NDJ5|uniprotkb:A8E4R5|uniprotkb:B1ARE7|uniprotkb:B1ARE8|uniprotkb:B1ARE9|uniprotkb:B1ARF0|uniprotkb:B7Z8Y2|uniprotkb:F8WEF7|ensembl:ENSP00000357905|ensembl:ENSP00000484603|ensembl:ENSP00000498825 psi-mi:prd16_human(display_long)|uniprotkb:PRDM16(gene name)|psi-mi:PRDM16(display_short)|uniprotkb:KIAA1675(gene name synonym)|uniprotkb:MEL1(gene name synonym)|uniprotkb:PFM13(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym)|uniprotkb:PR domain zinc finger protein 16(gene name synonym) psi-mi:dmbt1_human(display_long)|uniprotkb:Glycoprotein 340(gene name synonym)|uniprotkb:Surfactant pulmonary-associated D-binding protein(gene name synonym)|uniprotkb:Hensin(gene name synonym)|uniprotkb:DMBT1(gene name)|psi-mi:DMBT1(display_short)|uniprotkb:GP340(gene name synonym)|uniprotkb:Salivary agglutinin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483108|imex:IM-26985-347 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540247.1|refseq:NP_071397.3|refseq:NP_955533.2|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:Q9HAZ2|rcsb pdb:2N1I|rcsb pdb:6BW4|reactome:R-HSA-3214841|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|ensembl:ENSG00000142611(gene)|ensembl:ENST00000270722(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_004397.2|refseq:NP_015568.2|refseq:NP_060049.2|refseq:XP_011537690.1|refseq:XP_011537693.1|refseq:XP_011537707.1|refseq:NP_001307573.1|dip:DIP-50763N|ensembl:ENSG00000187908(gene)|ensembl:ENST00000368909(transcript)|ensembl:ENST00000619379(transcript)|ensembl:ENST00000652446(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006952"(defense response)|go:"GO:0015031"(protein transport)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035375"(zymogen binding)|go:"GO:0038187"(pattern recognition receptor activity)|go:"GO:0042494"(detection of bacterial lipoprotein)|go:"GO:0042589"(zymogen granule membrane)|go:"GO:0043152"(induction of bacterial agglutination)|go:"GO:0045087"(innate immune response)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050840"(extracellular matrix binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070891"(lipoteichoic acid binding)|go:"GO:1904399"(heparan sulfate binding)|interpro:IPR000859(CUB)|interpro:IPR001190(Speract/scavenger receptor)|interpro:IPR001507(Endoglin/CD105 antigen)|interpro:IPR017448(Speract/scavenger receptor related)|interpro:IPR017977|interpro:IPR035914|interpro:IPR036772|interpro:IPR042235|mint:Q9UGM3|rcsb pdb:6SA4|rcsb pdb:6SA5|rcsb pdb:6SAN|reactome:R-HSA-5683826 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:1adjB6FTm5Cp3QK0QQK2Iwmkk809606 rogid:A0Aw2F/rHW8mFmPDg4xOTy8NGzg9606 rigid:jg1/GgBhsIdyHcjbvmFbzJ/6u+s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HAZ2 uniprotkb:P35030 intact:EBI-2795620|uniprotkb:A6NHQ8|uniprotkb:B1AJP7|uniprotkb:B1AJP8|uniprotkb:B1AJP9|uniprotkb:B1WB48|uniprotkb:Q8WYJ9|uniprotkb:Q9C0I8|ensembl:ENSP00000270722 intact:EBI-1221209|uniprotkb:Q5VXV0|intact:EBI-2825937|uniprotkb:A8CED3|uniprotkb:F8W7P3|uniprotkb:Q6ISJ4|uniprotkb:P15951|uniprotkb:Q15665|uniprotkb:Q9UQV3|uniprotkb:A9Z1Y4|uniprotkb:E7ES07|uniprotkb:A8CED1 psi-mi:prd16_human(display_long)|uniprotkb:PRDM16(gene name)|psi-mi:PRDM16(display_short)|uniprotkb:KIAA1675(gene name synonym)|uniprotkb:MEL1(gene name synonym)|uniprotkb:PFM13(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym)|uniprotkb:PR domain zinc finger protein 16(gene name synonym) psi-mi:try3_human(display_long)|uniprotkb:PRSS3(gene name)|psi-mi:PRSS3(display_short)|uniprotkb:PRSS4(gene name synonym)|uniprotkb:TRY3(gene name synonym)|uniprotkb:TRY4(gene name synonym)|uniprotkb:Trypsin III(gene name synonym)|uniprotkb:Brain trypsinogen(gene name synonym)|uniprotkb:Mesotrypsinogen(gene name synonym)|uniprotkb:Trypsin IV(gene name synonym)|uniprotkb:Serine protease 3(gene name synonym)|uniprotkb:Serine protease 4(gene name synonym)|uniprotkb:Mesotrypsin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483108|imex:IM-26985-347 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540247.1|refseq:NP_071397.3|refseq:NP_955533.2|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:Q9HAZ2|rcsb pdb:2N1I|rcsb pdb:6BW4|reactome:R-HSA-3214841|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|ensembl:ENSG00000142611(gene)|ensembl:ENST00000270722(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_002762.2|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|refseq:NP_001184026.2|refseq:NP_031369.2|refseq:NP_001184027.1|mint:P35030|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0007586"(digestion)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0031638"(zymogen activation)|go:"GO:0043542"(endothelial cell migration)|go:"GO:1904724"(tertiary granule lumen)|rcsb pdb:1H4W|rcsb pdb:2R9P|rcsb pdb:3L33|rcsb pdb:3L3T|rcsb pdb:3P92|rcsb pdb:3P95|rcsb pdb:4DG4|rcsb pdb:4U30|rcsb pdb:4U32|rcsb pdb:5C67|rcsb pdb:5JBT|rcsb pdb:5TP0|rcsb pdb:6BX8|rcsb pdb:6GFI|reactome:R-HSA-1462054|reactome:R-HSA-196741|reactome:R-HSA-6798695|reactome:R-HSA-6803157|interpro:IPR043504 - - comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:1adjB6FTm5Cp3QK0QQK2Iwmkk809606 rogid:AEfz7orXeNoasizB5N76AkF4WMk9606 rigid:jg1/GgBhsIdyHcjbvmFbzJ/6u+s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HAZ2 uniprotkb:O14556 intact:EBI-2795620|uniprotkb:A6NHQ8|uniprotkb:B1AJP7|uniprotkb:B1AJP8|uniprotkb:B1AJP9|uniprotkb:B1WB48|uniprotkb:Q8WYJ9|uniprotkb:Q9C0I8|ensembl:ENSP00000270722 intact:EBI-1057431|uniprotkb:O60823|uniprotkb:Q6JTT9|uniprotkb:Q9HCU6|uniprotkb:B2RC82|ensembl:ENSP00000222286 psi-mi:prd16_human(display_long)|uniprotkb:PRDM16(gene name)|psi-mi:PRDM16(display_short)|uniprotkb:KIAA1675(gene name synonym)|uniprotkb:MEL1(gene name synonym)|uniprotkb:PFM13(gene name synonym)|uniprotkb:PR domain-containing protein 16(gene name synonym)|uniprotkb:Transcription factor MEL1(gene name synonym)|uniprotkb:PR domain zinc finger protein 16(gene name synonym) psi-mi:g3pt_human(display_long)|uniprotkb:GAPDHS(gene name)|psi-mi:GAPDHS(display_short)|uniprotkb:GAPD2(gene name synonym)|uniprotkb:GAPDH2(gene name synonym)|uniprotkb:GAPDS(gene name synonym)|uniprotkb:HSD35(orf name)|uniprotkb:HSD-35(orf name)|uniprotkb:Spermatogenic glyceraldehyde-3-phosphate dehydrogenase(gene name synonym)|uniprotkb:Spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483108|imex:IM-26985-347 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011540247.1|refseq:NP_071397.3|refseq:NP_955533.2|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR044410|mint:Q9HAZ2|rcsb pdb:2N1I|rcsb pdb:6BW4|reactome:R-HSA-3214841|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|ensembl:ENSG00000142611(gene)|ensembl:ENST00000270722(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016235"(aggresome)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030853"(negative regulation of granulocyte differentiation)|go:"GO:0043457"(regulation of cellular respiration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0070828"(heterochromatin organization)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_055179.1|ensembl:ENSG00000105679(gene)|ensembl:ENST00000222286(transcript)|go:"GO:0004365"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity")|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0050661"(NADP binding)|go:"GO:0051287"(NAD binding)|interpro:IPR006424(Glyceraldehyde-3-phosphate dehydrogenase, type I)|interpro:IPR020828|interpro:IPR020829|interpro:IPR020830|interpro:IPR020831|interpro:IPR036291|mint:O14556|rcsb pdb:3H9E|rcsb pdb:3PFW|rcsb pdb:5C7L|rcsb pdb:5C7O|reactome:R-HSA-390471|reactome:R-HSA-70171|reactome:R-HSA-70263 - - comment:"author score: 36" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:1adjB6FTm5Cp3QK0QQK2Iwmkk809606 rogid:R2wl89TyWYfD57yzx6up8t7LfDE9606 rigid:jg1/GgBhsIdyHcjbvmFbzJ/6u+s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UKN5 uniprotkb:P49902 intact:EBI-2803427|uniprotkb:Q9UFA6|ensembl:ENSP00000228437 intact:EBI-742084|uniprotkb:Q5JUV5|uniprotkb:D3DR91|ensembl:ENSP00000339479|ensembl:ENSP00000383960|ensembl:ENSP00000501689|ensembl:ENSP00000502205|ensembl:ENSP00000502679|ensembl:ENSP00000502801|uniprotkb:B7Z382 psi-mi:prdm4_human(display_long)|uniprotkb:PFM1(gene name synonym)|uniprotkb:PR domain-containing protein 4(gene name synonym)|uniprotkb:PRDM4(gene name)|psi-mi:PRDM4(display_short) psi-mi:5ntc_human(display_long)|uniprotkb:Cytosolic 5'-nucleotidase II(gene name synonym)|uniprotkb:NT5C2(gene name)|psi-mi:NT5C2(display_short)|uniprotkb:NT5B(gene name synonym)|uniprotkb:NT5CP(gene name synonym)|uniprotkb:PNT5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483132|imex:IM-26985-265 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000110851(gene)|ensembl:ENST00000228437(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017124(PR-domain zinc finger protein PRDM4)|interpro:IPR036236|interpro:IPR044404|mint:Q9UKN5|rcsb pdb:2L9Z|rcsb pdb:3DB5|reactome:R-HSA-193670|interpro:IPR041493|ensembl:ENSP00000228437|refseq:NP_036538.3 ensembl:ENST00000675326(transcript)|refseq:NP_001127845.1|refseq:NP_036361.1|ensembl:ENSG00000076685(gene)|ensembl:ENST00000343289(transcript)|ensembl:ENST00000404739(transcript)|ensembl:ENST00000674696(transcript)|ensembl:ENST00000676449(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005829"(cytosol)|go:"GO:0006204"(IMP catabolic process)|go:"GO:0008253"(5'-nucleotidase activity)|go:"GO:0019428"(allantoin biosynthetic process)|go:"GO:0046040"(IMP metabolic process)|go:"GO:0046085"(adenosine metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0050483"(IMP 5'-nucleotidase activity)|interpro:IPR008380(HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase)|interpro:IPR016695(Purine 5'-nucleotidase)|interpro:IPR023214|interpro:IPR036412|mint:P49902|rcsb pdb:2J2C|rcsb pdb:2JC9|rcsb pdb:2JCM|rcsb pdb:2XCV|rcsb pdb:2XCW|rcsb pdb:2XCX|rcsb pdb:2XJB|rcsb pdb:2XJC|rcsb pdb:2XJD|rcsb pdb:2XJE|rcsb pdb:2XJF|rcsb pdb:4H4B|rcsb pdb:5CQZ|rcsb pdb:5CR7|rcsb pdb:5K7Y|rcsb pdb:5L4Z|rcsb pdb:5L50|rcsb pdb:5OPK|rcsb pdb:5OPL|rcsb pdb:5OPM|rcsb pdb:5OPN|rcsb pdb:5OPO|rcsb pdb:5OPP|rcsb pdb:6DD3|rcsb pdb:6DDB|rcsb pdb:6DDC|rcsb pdb:6DDH|rcsb pdb:6DDK|rcsb pdb:6DDL|ensembl:ENST00000676428(transcript)|rcsb pdb:6DDO|rcsb pdb:6DDQ|rcsb pdb:6DDX|rcsb pdb:6DDY|rcsb pdb:6DDZ|rcsb pdb:6DE0|rcsb pdb:6DE1|rcsb pdb:6DE2|rcsb pdb:6DE3|rcsb pdb:6FIR|rcsb pdb:6FIS|rcsb pdb:6FIU|rcsb pdb:6FIW|rcsb pdb:6FXH|reactome:R-HSA-2161541|reactome:R-HSA-74259|refseq:XP_005269693.1|refseq:XP_005269696.1 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:VgdQaAPRDNbqz3qdRq7kNYvL39g9606 rogid:5CDp+/pOJ1IRk/ndDr4SGP0Ext89606 rigid:mu9mh+PQ8lCVQeST+PJMbJWVSVU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UKN5 uniprotkb:Q15208 intact:EBI-2803427|uniprotkb:Q9UFA6|ensembl:ENSP00000228437 intact:EBI-458376|ensembl:ENSP00000229812|uniprotkb:Q503A1 psi-mi:prdm4_human(display_long)|uniprotkb:PFM1(gene name synonym)|uniprotkb:PR domain-containing protein 4(gene name synonym)|uniprotkb:PRDM4(gene name)|psi-mi:PRDM4(display_short) psi-mi:stk38_human(display_long)|uniprotkb:NDR1(gene name synonym)|uniprotkb:STK38(gene name)|psi-mi:STK38(display_short)|uniprotkb:NDR1 protein kinase(gene name synonym)|uniprotkb:Nuclear Dbf2-related kinase 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483132|imex:IM-26985-265 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000110851(gene)|ensembl:ENST00000228437(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017124(PR-domain zinc finger protein PRDM4)|interpro:IPR036236|interpro:IPR044404|mint:Q9UKN5|rcsb pdb:2L9Z|rcsb pdb:3DB5|reactome:R-HSA-193670|interpro:IPR041493|ensembl:ENSP00000228437|refseq:NP_036538.3 ensembl:ENSG00000112079(gene)|ensembl:ENST00000229812(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|mint:Q15208|rcsb pdb:1PSB|rcsb pdb:6BXI|reactome:R-HSA-9013418|reactome:R-HSA-9013422|refseq:NP_009202.1|refseq:XP_006715051.1|refseq:XP_006715052.1|refseq:NP_001292031.1 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:VgdQaAPRDNbqz3qdRq7kNYvL39g9606 rogid:YHzdDrPEH6YdhOXtcnLWArqftck9606 rigid:mu9mh+PQ8lCVQeST+PJMbJWVSVU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UKN5 uniprotkb:P84090 intact:EBI-2803427|uniprotkb:Q9UFA6|ensembl:ENSP00000228437 intact:EBI-711389|uniprotkb:P70659|uniprotkb:Q14259|ensembl:ENSP00000451080|uniprotkb:B2R5H2 psi-mi:prdm4_human(display_long)|uniprotkb:PFM1(gene name synonym)|uniprotkb:PR domain-containing protein 4(gene name synonym)|uniprotkb:PRDM4(gene name)|psi-mi:PRDM4(display_short) psi-mi:erh_human(display_long)|uniprotkb:ERH(gene name)|psi-mi:ERH(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483132|imex:IM-26985-265 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000110851(gene)|ensembl:ENST00000228437(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017124(PR-domain zinc finger protein PRDM4)|interpro:IPR036236|interpro:IPR044404|mint:Q9UKN5|rcsb pdb:2L9Z|rcsb pdb:3DB5|reactome:R-HSA-193670|interpro:IPR041493|ensembl:ENSP00000228437|refseq:NP_036538.3 ensembl:ENSG00000100632(gene)|ensembl:ENST00000557016(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006213"(pyrimidine nucleoside metabolic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0030496"(midbody)|go:"GO:0034709"(methylosome)|interpro:IPR000781(Enhancer of rudimentary)|interpro:IPR035912|mint:P84090|rcsb pdb:1W9G|rcsb pdb:2NML|rcsb pdb:7CNC|refseq:NP_004441.1|dip:DIP-42473N - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:VgdQaAPRDNbqz3qdRq7kNYvL39g9606 rogid:foMOmvZ9wQyH0rrzBB2YlQhrT0g9606 rigid:mu9mh+PQ8lCVQeST+PJMbJWVSVU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UKN5 uniprotkb:P47929 intact:EBI-2803427|uniprotkb:Q9UFA6|ensembl:ENSP00000228437 intact:EBI-357504|ensembl:ENSP00000313571|ensembl:ENSP00000367891|ensembl:ENSP00000489395|ensembl:ENSP00000489582|uniprotkb:Q6IB87 psi-mi:prdm4_human(display_long)|uniprotkb:PFM1(gene name synonym)|uniprotkb:PR domain-containing protein 4(gene name synonym)|uniprotkb:PRDM4(gene name)|psi-mi:PRDM4(display_short) psi-mi:leg7_human(display_long)|uniprotkb:LGALS7(gene name)|psi-mi:LGALS7(display_short)|uniprotkb:PIG1(gene name synonym)|uniprotkb:HKL-14(gene name synonym)|uniprotkb:PI7(gene name synonym)|uniprotkb:p53-induced gene 1 protein(gene name synonym)|uniprotkb:LGALS7B(gene name)|psi-mi:LGALS7B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483132|imex:IM-26985-265 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000110851(gene)|ensembl:ENST00000228437(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017124(PR-domain zinc finger protein PRDM4)|interpro:IPR036236|interpro:IPR044404|mint:Q9UKN5|rcsb pdb:2L9Z|rcsb pdb:3DB5|reactome:R-HSA-193670|interpro:IPR041493|ensembl:ENSP00000228437|refseq:NP_036538.3 ensembl:ENSG00000178934(gene)|ensembl:ENSG00000205076(gene)|ensembl:ENSG00000282902(gene)|ensembl:ENSG00000283082(gene)|ensembl:ENST00000314980(transcript)|ensembl:ENST00000378626(transcript)|ensembl:ENST00000634448(transcript)|ensembl:ENST00000634800(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016936"(galactoside binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000562"(negative regulation of CD4-positive, alpha-beta T cell proliferation)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR030640|interpro:IPR044156|mint:P47929|rcsb pdb:1BKZ|rcsb pdb:2GAL|rcsb pdb:3GAL|rcsb pdb:3ZXE|rcsb pdb:3ZXF|rcsb pdb:4GAL|rcsb pdb:4UW3|rcsb pdb:4UW4|rcsb pdb:4UW5|rcsb pdb:4UW6|rcsb pdb:4XBQ|rcsb pdb:4Y26|rcsb pdb:5GAL|rcsb pdb:5H9Q|rcsb pdb:5H9S|refseq:NP_001035972.1|refseq:NP_002298.1 - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:VgdQaAPRDNbqz3qdRq7kNYvL39g9606 rogid:TIAlvVZ7rOYqTAGrYAFbJY231gc9606 rigid:mu9mh+PQ8lCVQeST+PJMbJWVSVU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UKN5 uniprotkb:P13861 intact:EBI-2803427|uniprotkb:Q9UFA6|ensembl:ENSP00000228437 intact:EBI-2556122|intact:EBI-6116682|uniprotkb:Q9BUB1|uniprotkb:Q16823|ensembl:ENSP00000265563|ensembl:ENSP00000394041|intact:EBI-10961724 psi-mi:prdm4_human(display_long)|uniprotkb:PFM1(gene name synonym)|uniprotkb:PR domain-containing protein 4(gene name synonym)|uniprotkb:PRDM4(gene name)|psi-mi:PRDM4(display_short) psi-mi:kap2_human(display_long)|uniprotkb:PKR2(gene name synonym)|uniprotkb:PRKAR2(gene name synonym)|uniprotkb:PRKAR2A(gene name)|psi-mi:PRKAR2A(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483132|imex:IM-26985-265 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000110851(gene)|ensembl:ENST00000228437(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017124(PR-domain zinc finger protein PRDM4)|interpro:IPR036236|interpro:IPR044404|mint:Q9UKN5|rcsb pdb:2L9Z|rcsb pdb:3DB5|reactome:R-HSA-193670|interpro:IPR041493|ensembl:ENSP00000228437|refseq:NP_036538.3 dip:DIP-552N|refseq:XP_011532244.1|interpro:IPR000595(Cyclic nucleotide-binding)|interpro:IPR003117(cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta)|interpro:IPR012198(cAMP-dependent protein kinase regulatory subunit)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR018488|interpro:IPR018490|mint:P13861|rcsb pdb:2IZX|rcsb pdb:2KYG|rcsb pdb:4ZP3|rcsb pdb:5H78|rcsb pdb:5XBY|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-180024|reactome:R-HSA-381676|reactome:R-HSA-432040|reactome:R-HSA-442720|reactome:R-HSA-5610787|reactome:R-HSA-9010642|reactome:R-HSA-9660821|reactome:R-HSA-9664323|reactome:R-HSA-983231|ensembl:ENSG00000114302(gene)|ensembl:ENST00000265563(transcript)|ensembl:ENST00000454963(transcript)|go:"GO:0004862"(cAMP-dependent protein kinase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005952"(cAMP-dependent protein kinase complex)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010738"(regulation of protein kinase A signaling)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030552"(cAMP binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043949"(regulation of cAMP-mediated signaling)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097546"(ciliary base)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|refseq:NP_001308911.1|refseq:NP_001308912.1|refseq:NP_004148.1|refseq:XP_016862304.1 - - comment:"author score: 33" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:VgdQaAPRDNbqz3qdRq7kNYvL39g9606 rogid:9Jf7EDZ9CZjeRERWwLAR0NyqFGQ9606 rigid:mu9mh+PQ8lCVQeST+PJMbJWVSVU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UKN5 uniprotkb:P11182 intact:EBI-2803427|uniprotkb:Q9UFA6|ensembl:ENSP00000228437 intact:EBI-359002|uniprotkb:Q5VVL8|uniprotkb:B2R811|intact:EBI-1058407|ensembl:ENSP00000359151 psi-mi:prdm4_human(display_long)|uniprotkb:PFM1(gene name synonym)|uniprotkb:PR domain-containing protein 4(gene name synonym)|uniprotkb:PRDM4(gene name)|psi-mi:PRDM4(display_short) psi-mi:odb2_human(display_long)|uniprotkb:DBT(gene name)|psi-mi:DBT(display_short)|uniprotkb:BCATE2(gene name synonym)|uniprotkb:"Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase"(gene name synonym)|uniprotkb:Dihydrolipoamide branched chain transacylase(gene name synonym)|uniprotkb:Dihydrolipoamide acetyltransferase component of branched-chain alpha-keto acid dehydrogenase complex(gene name synonym)|uniprotkb:Branched-chain alpha-keto acid dehydrogenase complex component E2(gene name synonym)|uniprotkb:52 kDa mitochondrial autoantigen of primary biliary cirrhosis(gene name synonym)|uniprotkb:Branched chain 2-oxo-acid dehydrogenase complex component E2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483132|imex:IM-26985-265 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000110851(gene)|ensembl:ENST00000228437(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017124(PR-domain zinc finger protein PRDM4)|interpro:IPR036236|interpro:IPR044404|mint:Q9UKN5|rcsb pdb:2L9Z|rcsb pdb:3DB5|reactome:R-HSA-193670|interpro:IPR041493|ensembl:ENSP00000228437|refseq:NP_036538.3 refseq:NP_001909.3|ensembl:ENSG00000137992(gene)|ensembl:ENST00000370132(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005947"(mitochondrial alpha-ketoglutarate dehydrogenase complex)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0031405"(lipoic acid binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043754"("dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity")|interpro:IPR000089(Biotin/lipoyl attachment)|interpro:IPR001078(Catalytic domain of components of various dehydrogenase complexes)|interpro:IPR003016(2-oxo acid dehydrogenase, lipoyl-binding site)|interpro:IPR004167(E3 binding)|interpro:IPR011053(Single hybrid motif)|interpro:IPR023213|interpro:IPR036625|mint:P11182|rcsb pdb:1K8M|rcsb pdb:1K8O|rcsb pdb:1ZWV|rcsb pdb:2COO|rcsb pdb:3RNM|reactome:R-HSA-389661|reactome:R-HSA-70895|reactome:R-HSA-9013407 - - comment:"author score: 40" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:VgdQaAPRDNbqz3qdRq7kNYvL39g9606 rogid:Q+c6k43BrkvtPPFCOW5pfJltPsU9606 rigid:mu9mh+PQ8lCVQeST+PJMbJWVSVU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQX1 uniprotkb:P10599 intact:EBI-4292031|uniprotkb:Q0VAJ0|uniprotkb:Q6NXQ7|ensembl:ENSP00000264808|uniprotkb:Q0VAI9 intact:EBI-594644|uniprotkb:B1ALW1|uniprotkb:O60744|uniprotkb:Q53X69|uniprotkb:Q96KI3|uniprotkb:Q9UDG5|intact:EBI-1042712|ensembl:ENSP00000363641 psi-mi:prdm5_human(display_long)|uniprotkb:PRDM5(gene name)|psi-mi:PRDM5(display_short)|uniprotkb:PFM2(gene name synonym)|uniprotkb:PR domain-containing protein 5(gene name synonym) psi-mi:thio_human(display_long)|uniprotkb:ATL-derived factor(gene name synonym)|uniprotkb:Surface-associated sulphydryl protein(gene name synonym)|uniprotkb:TXN(gene name)|psi-mi:TXN(display_short)|uniprotkb:TRDX(gene name synonym)|uniprotkb:TRX(gene name synonym)|uniprotkb:TRX1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483156|imex:IM-26985-563 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061169.2|refseq:NP_001287752.1|refseq:NP_001287753.1|ensembl:ENSG00000138738(gene)|ensembl:ENST00000264808(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016575"(histone deacetylation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051567"(histone H3-K9 methylation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017125(PR-domain zinc finger protein PRDM5)|interpro:IPR036236|interpro:IPR044415|mint:Q9NQX1|rcsb pdb:6XAZ|go:"GO:0016604"(nuclear body) refseq:NP_003320.2|refseq:NP_001231867.1|dip:DIP-6129N|ensembl:ENSG00000136810(gene)|ensembl:ENST00000374517(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006662"(glycerol ether metabolic process)|go:"GO:0009314"(response to radiation)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0047134"("protein-disulfide reductase (NAD(P)) activity")|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071731"(response to nitric oxide)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|go:"GO:2000170"(positive regulation of peptidyl-cysteine S-nitrosylation)|interpro:IPR005746(Thioredoxin)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:P10599|rcsb pdb:1AIU|rcsb pdb:1AUC|rcsb pdb:1CQG|rcsb pdb:1CQH|rcsb pdb:1ERT|rcsb pdb:1ERU|rcsb pdb:1ERV|rcsb pdb:1ERW|rcsb pdb:1M7T|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1TRS|rcsb pdb:1TRU|rcsb pdb:1TRV|rcsb pdb:1TRW|rcsb pdb:1W1C|rcsb pdb:1W1E|rcsb pdb:2HSH|rcsb pdb:2HXK|rcsb pdb:2IFQ|rcsb pdb:2IIY|rcsb pdb:3E3E|rcsb pdb:3KD0|rcsb pdb:3M9J|rcsb pdb:3M9K|rcsb pdb:3QFA|rcsb pdb:3QFB|rcsb pdb:3TRX|rcsb pdb:4LL1|rcsb pdb:4LL4|rcsb pdb:4OO4|rcsb pdb:4OO5|rcsb pdb:4POK|rcsb pdb:4POL|rcsb pdb:4POM|rcsb pdb:4PUF|rcsb pdb:4TRX|rcsb pdb:5DQY|reactome:R-HSA-2559580|reactome:R-HSA-3299685|reactome:R-HSA-499943|reactome:R-HSA-5628897|reactome:R-HSA-5676934|reactome:R-HSA-844456|reactome:R-HSA-9617629|reactome:R-HSA-9660826 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:VkUwoQb2LqxOCXK74Q3vvMT6JjE9606 rogid:5u+iJJtwAwAKXljKHnpY8h5uRkQ9606 rigid:e6kTgH72H1vy6R2Iys6vDvjTvH8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQX1 uniprotkb:P07477 intact:EBI-4292031|uniprotkb:Q0VAJ0|uniprotkb:Q6NXQ7|ensembl:ENSP00000264808|uniprotkb:Q0VAI9 intact:EBI-1222902|uniprotkb:A6NJ71|uniprotkb:Q92955|uniprotkb:Q9HAN4|uniprotkb:Q9HAN5|uniprotkb:Q9HAN6|uniprotkb:Q9HAN7|intact:EBI-1760472|intact:EBI-1965533|uniprotkb:A1A509|uniprotkb:Q5NV57|uniprotkb:Q7M4N3|uniprotkb:Q7M4N4|uniprotkb:B2R5I5|ensembl:ENSP00000308720|ensembl:ENSP00000479217 psi-mi:prdm5_human(display_long)|uniprotkb:PRDM5(gene name)|psi-mi:PRDM5(display_short)|uniprotkb:PFM2(gene name synonym)|uniprotkb:PR domain-containing protein 5(gene name synonym) psi-mi:try1_human(display_long)|uniprotkb:PRSS1(gene name)|psi-mi:PRSS1(display_short)|uniprotkb:TRP1(gene name synonym)|uniprotkb:TRY1(gene name synonym)|uniprotkb:TRYP1(gene name synonym)|uniprotkb:Trypsin I(gene name synonym)|uniprotkb:Cationic trypsinogen(gene name synonym)|uniprotkb:Serine protease 1(gene name synonym)|uniprotkb:Beta-trypsin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483156|imex:IM-26985-563 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_061169.2|refseq:NP_001287752.1|refseq:NP_001287753.1|ensembl:ENSG00000138738(gene)|ensembl:ENST00000264808(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016575"(histone deacetylation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051567"(histone H3-K9 methylation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001214(SET)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017125(PR-domain zinc finger protein PRDM5)|interpro:IPR036236|interpro:IPR044415|mint:Q9NQX1|rcsb pdb:6XAZ|go:"GO:0016604"(nuclear body) refseq:NP_002760.1|ensembl:ENSG00000204983(gene)|ensembl:ENSG00000274247(gene)|ensembl:ENST00000311737(transcript)|ensembl:ENST00000616256(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0007586"(digestion)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0072562"(blood microparticle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|mint:P07477|rcsb pdb:1FXY|rcsb pdb:1TRN|rcsb pdb:2RA3|rcsb pdb:4WWY|rcsb pdb:4WXV|reactome:R-HSA-1592389|reactome:R-HSA-196741 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:VkUwoQb2LqxOCXK74Q3vvMT6JjE9606 rogid:2elS/qMYj0sflxilyWfk3KPtGmo9606 rigid:e6kTgH72H1vy6R2Iys6vDvjTvH8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQW5 uniprotkb:P62979 intact:EBI-10312471|uniprotkb:A4Q9G8|uniprotkb:Q9NQW4|uniprotkb:Q08EM4|ensembl:ENSP00000396732 intact:EBI-357375|ensembl:ENSP00000272317|ensembl:ENSP00000383981|ensembl:ENSP00000385659|uniprotkb:P14798|uniprotkb:Q6LBL4|uniprotkb:Q9BQ77|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62988|uniprotkb:Q29120|uniprotkb:Q6LDU5|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9BWD6|uniprotkb:Q9BX98|uniprotkb:Q9UEF2|uniprotkb:Q9UEG1|uniprotkb:Q9UEK8|uniprotkb:Q9UPK7 psi-mi:prdm7_human(display_long)|uniprotkb:[histone H3]-lysine4 N-methyltransferase PRDM7(gene name synonym)|uniprotkb:PRDM7(gene name)|psi-mi:PRDM7(display_short)|uniprotkb:PFM4(gene name synonym)|uniprotkb:PR domain zinc finger protein 7(gene name synonym)|uniprotkb:PR domain-containing protein 7(gene name synonym) psi-mi:rs27a_human(display_long)|uniprotkb:RPS27A(gene name)|psi-mi:RPS27A(display_short)|uniprotkb:UBA80(gene name synonym)|uniprotkb:UBCEP1(gene name synonym)|uniprotkb:Ubiquitin carboxyl extension protein 80(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483197|imex:IM-26985-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001091643.1|refseq:XP_005256331.1|ensembl:ENSG00000126856(gene)|ensembl:ENST00000449207(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010844"(recombination hotspot binding)|go:"GO:0010845"(positive regulation of reciprocal meiotic recombination)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR001214(SET)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003655(Krueppel-associated box-related)|interpro:IPR019041|interpro:IPR036051|mint:Q9NQW5|reactome:R-HSA-212436|interpro:IPR044417 reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8863795|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-8854050|reactome:R-HSA-8951664|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9633012|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9683683|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-975110|reactome:R-HSA-975163|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-977225|reactome:R-HSA-983168|reactome:R-HSA-975144|ensembl:ENSG00000143947(gene)|ensembl:ENST00000272317(transcript)|ensembl:ENST00000402285(transcript)|ensembl:ENST00000404735(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0010008"(endosome membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000626(Ubiquitin)|interpro:IPR002906(Ribosomal protein S27a)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038582|mint:P62979|rcsb pdb:2KHW|rcsb pdb:2KOX|rcsb pdb:2KTF|rcsb pdb:2KWU|rcsb pdb:2KWV|rcsb pdb:2L0F|rcsb pdb:2L0T|rcsb pdb:2XK5|rcsb pdb:3AXC|rcsb pdb:3I3T|rcsb pdb:3K9P|rcsb pdb:3N30|rcsb pdb:3N32|rcsb pdb:3NHE|rcsb pdb:3NOB|rcsb pdb:3NS8|rcsb pdb:3PHD|rcsb pdb:3PHW|rcsb pdb:3TBL|rcsb pdb:3VDZ|rcsb pdb:4R62|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:5A2Q|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:5AJ0|rcsb pdb:6IP8|rcsb pdb:6J99|rcsb pdb:5FLX|rcsb pdb:6KFP|rcsb pdb:5LKS|rcsb pdb:6KG6|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SQO|rcsb pdb:5T2C|rcsb pdb:5WVO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:5YDK|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6DC6|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:7K5I|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|reactome:R-HSA-1253288|reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6ZXF|reactome:R-HSA-162588|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-168928|rcsb pdb:6ZXG|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|rcsb pdb:6ZXH|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-1799339|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|rcsb pdb:7A09|rcsb pdb:7BWD|reactome:R-HSA-192823|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-2565942|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-349425|reactome:R-HSA-211733|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-2122947|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-2122948|reactome:R-HSA-4641258|reactome:R-HSA-2173788|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-2173791|reactome:R-HSA-5357905|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2408557|reactome:R-HSA-2467813|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-2559585|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5656169|reactome:R-HSA-5656121|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6791226|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69231|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-8852276|refseq:NP_001129064.1|refseq:NP_001170884.1|refseq:NP_002945.1 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BpQEMtF3jbZDafR2joepeE2py+09606 rogid:2LSJafy6vjKHYZcZVx8zZaOXRis9606 rigid:OOBKBrP+FY5bH2YShqeuFnk/6Ww false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQW5 uniprotkb:P62316 intact:EBI-10312471|uniprotkb:A4Q9G8|uniprotkb:Q9NQW4|uniprotkb:Q08EM4|ensembl:ENSP00000396732 intact:EBI-297993|uniprotkb:P43330|ensembl:ENSP00000342374|ensembl:ENSP00000465216|uniprotkb:A8K797|uniprotkb:J3KPM5 psi-mi:prdm7_human(display_long)|uniprotkb:[histone H3]-lysine4 N-methyltransferase PRDM7(gene name synonym)|uniprotkb:PRDM7(gene name)|psi-mi:PRDM7(display_short)|uniprotkb:PFM4(gene name synonym)|uniprotkb:PR domain zinc finger protein 7(gene name synonym)|uniprotkb:PR domain-containing protein 7(gene name synonym) psi-mi:smd2_human(display_long)|uniprotkb:SNRPD2(gene name)|psi-mi:SNRPD2(display_short)|uniprotkb:snRNP core protein D2(gene name synonym)|uniprotkb:SNRPD1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483197|imex:IM-26985-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001091643.1|refseq:XP_005256331.1|ensembl:ENSG00000126856(gene)|ensembl:ENST00000449207(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010844"(recombination hotspot binding)|go:"GO:0010845"(positive regulation of reciprocal meiotic recombination)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR001214(SET)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003655(Krueppel-associated box-related)|interpro:IPR019041|interpro:IPR036051|mint:Q9NQW5|reactome:R-HSA-212436|interpro:IPR044417 ensembl:ENSG00000125743(gene)|ensembl:ENST00000342669(transcript)|ensembl:ENST00000588301(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990446"(U1 snRNP binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027248|mint:P62316|rcsb pdb:1B34|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:NP_004588.1|refseq:NP_808210.2|dip:DIP-31219N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BpQEMtF3jbZDafR2joepeE2py+09606 rogid:4OshNPT6N4dOcWMVXrF5Fm8dcnI9606 rigid:OOBKBrP+FY5bH2YShqeuFnk/6Ww false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQW5 uniprotkb:Q5JUX0 intact:EBI-10312471|uniprotkb:A4Q9G8|uniprotkb:Q9NQW4|uniprotkb:Q08EM4|ensembl:ENSP00000396732 intact:EBI-1642527|uniprotkb:Q8N5D9|uniprotkb:B7Z8W2|uniprotkb:B2RUW3|ensembl:ENSP00000364054|ensembl:ENSP00000491179|ensembl:ENSP00000491624|ensembl:ENSP00000491751|ensembl:ENSP00000492344|ensembl:ENSP00000492381|ensembl:ENSP00000492795 psi-mi:prdm7_human(display_long)|uniprotkb:[histone H3]-lysine4 N-methyltransferase PRDM7(gene name synonym)|uniprotkb:PRDM7(gene name)|psi-mi:PRDM7(display_short)|uniprotkb:PFM4(gene name synonym)|uniprotkb:PR domain zinc finger protein 7(gene name synonym)|uniprotkb:PR domain-containing protein 7(gene name synonym) psi-mi:spin3_human(display_long)|uniprotkb:SPIN3(gene name)|psi-mi:SPIN3(display_short)|uniprotkb:Spindlin-like protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483197|imex:IM-26985-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001091643.1|refseq:XP_005256331.1|ensembl:ENSG00000126856(gene)|ensembl:ENST00000449207(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010844"(recombination hotspot binding)|go:"GO:0010845"(positive regulation of reciprocal meiotic recombination)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR001214(SET)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003655(Krueppel-associated box-related)|interpro:IPR019041|interpro:IPR036051|mint:Q9NQW5|reactome:R-HSA-212436|interpro:IPR044417 refseq:NP_001010862.2|refseq:XP_006724640.1|refseq:XP_006724641.1|refseq:XP_016884804.1|ensembl:ENSG00000204271(gene)|ensembl:ENST00000374919(transcript)|ensembl:ENST00000638257(transcript)|ensembl:ENST00000638289(transcript)|ensembl:ENST00000638386(transcript)|ensembl:ENST00000638712(transcript)|ensembl:ENST00000639007(transcript)|ensembl:ENST00000639605(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007276"(gamete generation)|go:"GO:0035064"(methylated histone binding)|interpro:IPR003671(Spindlin/spermiogenesis-specific protein)|interpro:IPR029567|interpro:IPR042567|mint:Q5JUX0|rcsb pdb:5A1H - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BpQEMtF3jbZDafR2joepeE2py+09606 rogid:Z4PHGiFUPGeFRxSjg6rzBFnXv7g9606 rigid:OOBKBrP+FY5bH2YShqeuFnk/6Ww false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQW5 uniprotkb:Q13643 intact:EBI-10312471|uniprotkb:A4Q9G8|uniprotkb:Q9NQW4|uniprotkb:Q08EM4|ensembl:ENSP00000396732 intact:EBI-741101|ensembl:ENSP00000362107|uniprotkb:Q6I9T0|uniprotkb:Q9BVA2|uniprotkb:D3DPT6 psi-mi:prdm7_human(display_long)|uniprotkb:[histone H3]-lysine4 N-methyltransferase PRDM7(gene name synonym)|uniprotkb:PRDM7(gene name)|psi-mi:PRDM7(display_short)|uniprotkb:PFM4(gene name synonym)|uniprotkb:PR domain zinc finger protein 7(gene name synonym)|uniprotkb:PR domain-containing protein 7(gene name synonym) psi-mi:fhl3_human(display_long)|uniprotkb:FHL3(gene name)|psi-mi:FHL3(display_short)|uniprotkb:SLIM2(gene name synonym)|uniprotkb:Skeletal muscle LIM-protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483197|imex:IM-26985-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001091643.1|refseq:XP_005256331.1|ensembl:ENSG00000126856(gene)|ensembl:ENST00000449207(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010844"(recombination hotspot binding)|go:"GO:0010845"(positive regulation of reciprocal meiotic recombination)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR001214(SET)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003655(Krueppel-associated box-related)|interpro:IPR019041|interpro:IPR036051|mint:Q9NQW5|reactome:R-HSA-212436|interpro:IPR044417 refseq:NP_004459.2|ensembl:ENSG00000183386(gene)|ensembl:ENST00000373016(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005925"(focal adhesion)|go:"GO:0007517"(muscle organ development)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0046872"(metal ion binding)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q13643|rcsb pdb:1WYH|rcsb pdb:2CUQ|rcsb pdb:2EHE|interpro:IPR037987|refseq:NP_001230807.1|dip:DIP-42030N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BpQEMtF3jbZDafR2joepeE2py+09606 rogid:RAo+b/VgFSnHSbgR+zXuxJvypxM9606 rigid:OOBKBrP+FY5bH2YShqeuFnk/6Ww false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQW5 uniprotkb:Q99865 intact:EBI-10312471|uniprotkb:A4Q9G8|uniprotkb:Q9NQW4|uniprotkb:Q08EM4|ensembl:ENSP00000396732 intact:EBI-25483168|ensembl:ENSP00000364041|ensembl:ENSP00000364043|uniprotkb:O75650|uniprotkb:Q6IPW2|uniprotkb:Q9UJJ0 psi-mi:prdm7_human(display_long)|uniprotkb:[histone H3]-lysine4 N-methyltransferase PRDM7(gene name synonym)|uniprotkb:PRDM7(gene name)|psi-mi:PRDM7(display_short)|uniprotkb:PFM4(gene name synonym)|uniprotkb:PR domain zinc finger protein 7(gene name synonym)|uniprotkb:PR domain-containing protein 7(gene name synonym) psi-mi:spi2a_human(display_long)|uniprotkb:SPIN2A(gene name)|psi-mi:SPIN2A(display_short)|uniprotkb:DXF34(gene name synonym)|uniprotkb:SPIN2(gene name synonym)|uniprotkb:Protein DXF34(gene name synonym)|uniprotkb:Spindlin-like protein 2A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483197|imex:IM-26985-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001091643.1|refseq:XP_005256331.1|ensembl:ENSG00000126856(gene)|ensembl:ENST00000449207(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010844"(recombination hotspot binding)|go:"GO:0010845"(positive regulation of reciprocal meiotic recombination)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR001214(SET)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003655(Krueppel-associated box-related)|interpro:IPR019041|interpro:IPR036051|mint:Q9NQW5|reactome:R-HSA-212436|interpro:IPR044417 ensembl:ENSG00000147059(gene)|ensembl:ENST00000374906(transcript)|ensembl:ENST00000374908(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0007276"(gamete generation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0051726"(regulation of cell cycle)|interpro:IPR003671(Spindlin/spermiogenesis-specific protein)|interpro:IPR029564|interpro:IPR042567|mint:Q99865|refseq:NP_061876.3|refseq:XP_005262073.3|refseq:XP_005262074.3|refseq:XP_005262076.1|refseq:XP_016885087.1 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BpQEMtF3jbZDafR2joepeE2py+09606 rogid:fd0LwjY2zf4PeaRNs2aUbx8wJG89606 rigid:OOBKBrP+FY5bH2YShqeuFnk/6Ww false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQW5 uniprotkb:Q9Y281 intact:EBI-10312471|uniprotkb:A4Q9G8|uniprotkb:Q9NQW4|uniprotkb:Q08EM4|ensembl:ENSP00000396732 intact:EBI-351218|uniprotkb:G3V5P4|ensembl:ENSP00000298159|ensembl:ENSP00000340635|ensembl:ENSP00000500375|ensembl:ENSP00000500532 psi-mi:prdm7_human(display_long)|uniprotkb:[histone H3]-lysine4 N-methyltransferase PRDM7(gene name synonym)|uniprotkb:PRDM7(gene name)|psi-mi:PRDM7(display_short)|uniprotkb:PFM4(gene name synonym)|uniprotkb:PR domain zinc finger protein 7(gene name synonym)|uniprotkb:PR domain-containing protein 7(gene name synonym) psi-mi:cof2_human(display_long)|uniprotkb:CFL2(gene name)|psi-mi:CFL2(display_short)|uniprotkb:Cofilin, muscle isoform(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483197|imex:IM-26985-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001091643.1|refseq:XP_005256331.1|ensembl:ENSG00000126856(gene)|ensembl:ENST00000449207(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010844"(recombination hotspot binding)|go:"GO:0010845"(positive regulation of reciprocal meiotic recombination)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR001214(SET)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003655(Krueppel-associated box-related)|interpro:IPR019041|interpro:IPR036051|mint:Q9NQW5|reactome:R-HSA-212436|interpro:IPR044417 refseq:NP_068733.1|refseq:NP_619579.1|refseq:XP_011534665.1|refseq:NP_001230574.1|dip:DIP-33178N|ensembl:ENSG00000165410(gene)|ensembl:ENST00000298159(transcript)|ensembl:ENST00000341223(transcript)|ensembl:ENST00000672163(transcript)|ensembl:ENST00000672517(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030018"(Z disc)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030043"(actin filament fragmentation)|go:"GO:0030836"(positive regulation of actin filament depolymerization)|go:"GO:0031674"(I band)|go:"GO:0045214"(sarcomere organization)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048870"(cell motility)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR017904|interpro:IPR029006|mint:Q9Y281 - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BpQEMtF3jbZDafR2joepeE2py+09606 rogid:HwYoUPZRkuRzqMLvuQctwNCOREA9606 rigid:OOBKBrP+FY5bH2YShqeuFnk/6Ww false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQW5 uniprotkb:Q9UBQ7 intact:EBI-10312471|uniprotkb:A4Q9G8|uniprotkb:Q9NQW4|uniprotkb:Q08EM4|ensembl:ENSP00000396732 intact:EBI-372445|uniprotkb:Q9H3E9|uniprotkb:Q9UKX1|ensembl:ENSP00000313432|uniprotkb:Q5T945|uniprotkb:Q9H636 psi-mi:prdm7_human(display_long)|uniprotkb:[histone H3]-lysine4 N-methyltransferase PRDM7(gene name synonym)|uniprotkb:PRDM7(gene name)|psi-mi:PRDM7(display_short)|uniprotkb:PFM4(gene name synonym)|uniprotkb:PR domain zinc finger protein 7(gene name synonym)|uniprotkb:PR domain-containing protein 7(gene name synonym) psi-mi:grhpr_human(display_long)|uniprotkb:MSTP035(orf name)|uniprotkb:GRHPR(gene name)|psi-mi:GRHPR(display_short)|uniprotkb:GLXR(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483197|imex:IM-26985-47 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001091643.1|refseq:XP_005256331.1|ensembl:ENSG00000126856(gene)|ensembl:ENST00000449207(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010844"(recombination hotspot binding)|go:"GO:0010845"(positive regulation of reciprocal meiotic recombination)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR001214(SET)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003655(Krueppel-associated box-related)|interpro:IPR019041|interpro:IPR036051|mint:Q9NQW5|reactome:R-HSA-212436|interpro:IPR044417 refseq:NP_036335.1|go:"GO:0043648"(dicarboxylic acid metabolic process)|go:"GO:0046487"(glyoxylate metabolic process)|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070402"(NADPH binding)|go:"GO:1902494"(catalytic complex)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029753|interpro:IPR036291|mint:Q9UBQ7|rcsb pdb:2GCG|rcsb pdb:2H1S|rcsb pdb:2Q50|rcsb pdb:2WWR|reactome:R-HSA-389661|ensembl:ENSG00000137106(gene)|ensembl:ENST00000318158(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0007588"(excretion)|go:"GO:0008465"(glycerate dehydrogenase activity)|go:"GO:0016618"(hydroxypyruvate reductase activity)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0030267"("glyoxylate reductase (NADP+) activity")|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0042803"(protein homodimerization activity) - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:BpQEMtF3jbZDafR2joepeE2py+09606 rogid:qPHrh5I5wHI5MWba4zncz26cUnQ9606 rigid:OOBKBrP+FY5bH2YShqeuFnk/6Ww false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQV7 uniprotkb:P67809 intact:EBI-17257586|uniprotkb:B4DX22|uniprotkb:Q27Q50|ensembl:ENSP00000296682 intact:EBI-354065|uniprotkb:P16990|uniprotkb:P16991|uniprotkb:Q14972|uniprotkb:Q15325|uniprotkb:Q5FVF0|ensembl:ENSP00000361626 psi-mi:prdm9_human(display_long)|uniprotkb:Protein-lysine N-methyltransferase PRDM9(gene name synonym)|uniprotkb:PRDM9(gene name)|psi-mi:PRDM9(display_short)|uniprotkb:PFM6(gene name synonym)|uniprotkb:[histone H3]-lysine36 N-trimethyltransferase PRDM9(gene name synonym)|uniprotkb:PR domain zinc finger protein 9(gene name synonym)|uniprotkb:PR domain-containing protein 9(gene name synonym)|uniprotkb:[histone H3]-lysine4 N-trimethyltransferase PRDM9(gene name synonym)|uniprotkb:[histone H3]-lysine9 N-trimethyltransferase PRDM9(gene name synonym)|uniprotkb:[histone H4]-N-methyl-L-lysine20 N-methyltransferase PRDM9(gene name synonym)|uniprotkb:[histone H4]-lysine20 N-methyltransferase PRDM9(gene name synonym) psi-mi:ybox1_human(display_long)|uniprotkb:YBX1(gene name)|psi-mi:YBX1(display_short)|uniprotkb:YB1(gene name synonym)|uniprotkb:NSEP1(gene name synonym)|uniprotkb:Y-box transcription factor(gene name synonym)|uniprotkb:CCAAT-binding transcription factor I subunit A(gene name synonym)|uniprotkb:Enhancer factor I subunit A(gene name synonym)|uniprotkb:DNA-binding protein B(gene name synonym)|uniprotkb:Nuclease-sensitive element-binding protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483259|imex:IM-26985-503 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001297143.1|refseq:NP_064612.2|ensembl:ENSG00000164256(gene)|ensembl:ENST00000296682(transcript)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006311"(meiotic gene conversion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007292"(female gamete generation)|go:"GO:0048232"(male gamete generation)|go:"GO:0051567"(histone H3-K9 methylation)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097198"(histone H3-K36 trimethylation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0097676"(histone H3-K36 dimethylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:0010844"(recombination hotspot binding)|go:"GO:1905437"(positive regulation of histone H3-K4 trimethylation)|go:"GO:1905516"(positive regulation of fertilization)|go:"GO:0010845"(positive regulation of reciprocal meiotic recombination)|go:"GO:1990918"(double-strand break repair involved in meiotic recombination)|go:"GO:0016584"(nucleosome positioning)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR001214(SET)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003655(Krueppel-associated box-related)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR019041|interpro:IPR036051|interpro:IPR036236|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|interpro:IPR044417|mint:Q9NQV7|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|rcsb pdb:4IJD|rcsb pdb:5EGB|rcsb pdb:5EH2|rcsb pdb:5EI9|rcsb pdb:6NM4|reactome:R-HSA-3214841|reactome:R-HSA-912446 refseq:NP_004550.2|dip:DIP-29405N|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990428"(miRNA transport)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P67809|rcsb pdb:1H95|rcsb pdb:5YTS|rcsb pdb:5YTT|rcsb pdb:5YTV|rcsb pdb:5YTX|rcsb pdb:6A6L|rcsb pdb:6KTC|rcsb pdb:6KUG|rcsb pdb:6LMR|rcsb pdb:6LMS|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-9017802|ensembl:ENSG00000065978(gene)|ensembl:ENST00000321358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0008544"(epidermis development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035198"(miRNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050658"(RNA transport)|go:"GO:0051020"(GTPase binding)|go:"GO:0051031"(tRNA transport)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding) - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pj+BI9XftnXTGBd2Q6WY4ptZU8g9606 rogid:0/mAXOzokPlDByFFzGTP8bp9nqo9606 rigid:B1C5MdFohTdfnQK2K/uipUJgW0E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQV7 uniprotkb:Q9Y6H1 intact:EBI-17257586|uniprotkb:B4DX22|uniprotkb:Q27Q50|ensembl:ENSP00000296682 intact:EBI-2321769|uniprotkb:Q498C3|uniprotkb:Q6NZ50|ensembl:ENSP00000378812 psi-mi:prdm9_human(display_long)|uniprotkb:Protein-lysine N-methyltransferase PRDM9(gene name synonym)|uniprotkb:PRDM9(gene name)|psi-mi:PRDM9(display_short)|uniprotkb:PFM6(gene name synonym)|uniprotkb:[histone H3]-lysine36 N-trimethyltransferase PRDM9(gene name synonym)|uniprotkb:PR domain zinc finger protein 9(gene name synonym)|uniprotkb:PR domain-containing protein 9(gene name synonym)|uniprotkb:[histone H3]-lysine4 N-trimethyltransferase PRDM9(gene name synonym)|uniprotkb:[histone H3]-lysine9 N-trimethyltransferase PRDM9(gene name synonym)|uniprotkb:[histone H4]-N-methyl-L-lysine20 N-methyltransferase PRDM9(gene name synonym)|uniprotkb:[histone H4]-lysine20 N-methyltransferase PRDM9(gene name synonym) psi-mi:chch2_human(display_long)|uniprotkb:CHCHD2(gene name)|psi-mi:CHCHD2(display_short)|uniprotkb:C7orf17(gene name synonym)|uniprotkb:HCV NS2 trans-regulated protein(gene name synonym)|uniprotkb:Aging-associated gene 10 protein(gene name synonym)|uniprotkb:AAG10(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483259|imex:IM-26985-503 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001297143.1|refseq:NP_064612.2|ensembl:ENSG00000164256(gene)|ensembl:ENST00000296682(transcript)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006311"(meiotic gene conversion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007292"(female gamete generation)|go:"GO:0048232"(male gamete generation)|go:"GO:0051567"(histone H3-K9 methylation)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097198"(histone H3-K36 trimethylation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0097676"(histone H3-K36 dimethylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:0010844"(recombination hotspot binding)|go:"GO:1905437"(positive regulation of histone H3-K4 trimethylation)|go:"GO:1905516"(positive regulation of fertilization)|go:"GO:0010845"(positive regulation of reciprocal meiotic recombination)|go:"GO:1990918"(double-strand break repair involved in meiotic recombination)|go:"GO:0016584"(nucleosome positioning)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR001214(SET)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003655(Krueppel-associated box-related)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR019041|interpro:IPR036051|interpro:IPR036236|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|interpro:IPR044417|mint:Q9NQV7|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|rcsb pdb:4IJD|rcsb pdb:5EGB|rcsb pdb:5EH2|rcsb pdb:5EI9|rcsb pdb:6NM4|reactome:R-HSA-3214841|reactome:R-HSA-912446 refseq:NP_057223.1|ensembl:ENSG00000106153(gene)|ensembl:ENST00000395422(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900037"(regulation of cellular response to hypoxia)|go:"GO:1905448"(positive regulation of mitochondrial ATP synthesis coupled electron transport)|interpro:IPR010625(CHCH)|mint:Q9Y6H1|reactome:R-HSA-1268020 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pj+BI9XftnXTGBd2Q6WY4ptZU8g9606 rogid:fdx3lE51+yZ1k3uwh8/LDKJC+CQ9606 rigid:B1C5MdFohTdfnQK2K/uipUJgW0E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQV7 uniprotkb:Q13501 intact:EBI-17257586|uniprotkb:B4DX22|uniprotkb:Q27Q50|ensembl:ENSP00000296682 intact:EBI-307104|uniprotkb:Q13446|uniprotkb:Q9BUV7|uniprotkb:Q9BVS6|uniprotkb:Q9UEU1|uniprotkb:A6NFN7|uniprotkb:B2R661|uniprotkb:B3KUW5|intact:EBI-28976133|ensembl:ENSP00000374455 psi-mi:prdm9_human(display_long)|uniprotkb:Protein-lysine N-methyltransferase PRDM9(gene name synonym)|uniprotkb:PRDM9(gene name)|psi-mi:PRDM9(display_short)|uniprotkb:PFM6(gene name synonym)|uniprotkb:[histone H3]-lysine36 N-trimethyltransferase PRDM9(gene name synonym)|uniprotkb:PR domain zinc finger protein 9(gene name synonym)|uniprotkb:PR domain-containing protein 9(gene name synonym)|uniprotkb:[histone H3]-lysine4 N-trimethyltransferase PRDM9(gene name synonym)|uniprotkb:[histone H3]-lysine9 N-trimethyltransferase PRDM9(gene name synonym)|uniprotkb:[histone H4]-N-methyl-L-lysine20 N-methyltransferase PRDM9(gene name synonym)|uniprotkb:[histone H4]-lysine20 N-methyltransferase PRDM9(gene name synonym) psi-mi:sqstm_human(display_long)|uniprotkb:SQSTM1(gene name)|psi-mi:SQSTM1(display_short)|uniprotkb:ORCA(gene name synonym)|uniprotkb:OSIL(gene name synonym)|uniprotkb:Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa(gene name synonym)|uniprotkb:Ubiquitin-binding protein p62(gene name synonym)|uniprotkb:EBI3-associated protein of 60 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483259|imex:IM-26985-503 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001297143.1|refseq:NP_064612.2|ensembl:ENSG00000164256(gene)|ensembl:ENST00000296682(transcript)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006311"(meiotic gene conversion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007292"(female gamete generation)|go:"GO:0048232"(male gamete generation)|go:"GO:0051567"(histone H3-K9 methylation)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097198"(histone H3-K36 trimethylation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0097676"(histone H3-K36 dimethylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:0010844"(recombination hotspot binding)|go:"GO:1905437"(positive regulation of histone H3-K4 trimethylation)|go:"GO:1905516"(positive regulation of fertilization)|go:"GO:0010845"(positive regulation of reciprocal meiotic recombination)|go:"GO:1990918"(double-strand break repair involved in meiotic recombination)|go:"GO:0016584"(nucleosome positioning)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR001214(SET)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003655(Krueppel-associated box-related)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR019041|interpro:IPR036051|interpro:IPR036236|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|interpro:IPR044417|mint:Q9NQV7|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|rcsb pdb:4IJD|rcsb pdb:5EGB|rcsb pdb:5EH2|rcsb pdb:5EI9|rcsb pdb:6NM4|reactome:R-HSA-3214841|reactome:R-HSA-912446 ensembl:ENST00000360718|ensembl:ENSP00000353944|ensembl:ENSP00000374455|ensembl:ENSG00000161011(gene)|ensembl:ENST00000389805(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0000423"(mitophagy)|go:"GO:0000932"(P-body)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002376"(immune system process)|go:"GO:0002931"(response to ischemia)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0007032"(endosome organization)|go:"GO:0008104"(protein localization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016234"(inclusion body)|go:"GO:0016235"(aggresome)|go:"GO:0016236"(macroautophagy)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030154"(cell differentiation)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035973"(aggrephagy)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046578"(regulation of Ras protein signal transduction)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061912"(selective autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097413"(Lewy body)|go:"GO:0098780"(response to mitochondrial depolarisation)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905719"(protein localization to perinuclear region of cytoplasm)|interpro:IPR000270(Octicosapeptide/Phox/Bem1p)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR009060(UBA-like)|go:"GO:0043130"(ubiquitin binding)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR033741|go:"GO:0044753"(amphisome)|interpro:IPR034866|interpro:IPR043145|mint:Q13501|rcsb pdb:1Q02|rcsb pdb:2JY7|rcsb pdb:2JY8|rcsb pdb:2K0B|rcsb pdb:2KNV|go:"GO:0044754"(autolysosome)|rcsb pdb:4MJS|rcsb pdb:4UF8|rcsb pdb:4UF9|go:"GO:0044877"(protein-containing complex binding)|rcsb pdb:5YP7|rcsb pdb:5YP8|rcsb pdb:5YPA|rcsb pdb:5YPB|rcsb pdb:5YPC|rcsb pdb:5YPE|rcsb pdb:5YPF|rcsb pdb:5YPG|rcsb pdb:5YPH|rcsb pdb:6JM4|rcsb pdb:6KHZ|rcsb pdb:6MJ7|rcsb pdb:6TGY|rcsb pdb:6TH3|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-5205685|reactome:R-HSA-9020702|reactome:R-HSA-9664873|refseq:NP_001135770.1|refseq:NP_001135771.1|refseq:NP_003891.1|dip:DIP-34443N|refseq:XP_016865499.1 - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pj+BI9XftnXTGBd2Q6WY4ptZU8g9606 rogid:paIcBLmyiv1+D9QMym5MY3yc8MI9606 rigid:B1C5MdFohTdfnQK2K/uipUJgW0E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQV7 uniprotkb:A4D256 intact:EBI-17257586|uniprotkb:B4DX22|uniprotkb:Q27Q50|ensembl:ENSP00000296682 intact:EBI-25483224|ensembl:ENSP00000497792|uniprotkb:Q2VIP7|uniprotkb:Q6NUS3|uniprotkb:Q8NCT2 psi-mi:prdm9_human(display_long)|uniprotkb:Protein-lysine N-methyltransferase PRDM9(gene name synonym)|uniprotkb:PRDM9(gene name)|psi-mi:PRDM9(display_short)|uniprotkb:PFM6(gene name synonym)|uniprotkb:[histone H3]-lysine36 N-trimethyltransferase PRDM9(gene name synonym)|uniprotkb:PR domain zinc finger protein 9(gene name synonym)|uniprotkb:PR domain-containing protein 9(gene name synonym)|uniprotkb:[histone H3]-lysine4 N-trimethyltransferase PRDM9(gene name synonym)|uniprotkb:[histone H3]-lysine9 N-trimethyltransferase PRDM9(gene name synonym)|uniprotkb:[histone H4]-N-methyl-L-lysine20 N-methyltransferase PRDM9(gene name synonym)|uniprotkb:[histone H4]-lysine20 N-methyltransferase PRDM9(gene name synonym) psi-mi:cc14c_human(display_long)|uniprotkb:CDC14C(gene name)|psi-mi:CDC14C(display_short)|uniprotkb:CDC14B2(gene name synonym)|uniprotkb:CDC14Bretro(gene name synonym)|uniprotkb:CDC14 cell division cycle 14 homolog C(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483259|imex:IM-26985-503 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001297143.1|refseq:NP_064612.2|ensembl:ENSG00000164256(gene)|ensembl:ENST00000296682(transcript)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006311"(meiotic gene conversion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007292"(female gamete generation)|go:"GO:0048232"(male gamete generation)|go:"GO:0051567"(histone H3-K9 methylation)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097198"(histone H3-K36 trimethylation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0097676"(histone H3-K36 dimethylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:0010844"(recombination hotspot binding)|go:"GO:1905437"(positive regulation of histone H3-K4 trimethylation)|go:"GO:1905516"(positive regulation of fertilization)|go:"GO:0010845"(positive regulation of reciprocal meiotic recombination)|go:"GO:1990918"(double-strand break repair involved in meiotic recombination)|go:"GO:0016584"(nucleosome positioning)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR001214(SET)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003655(Krueppel-associated box-related)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR019041|interpro:IPR036051|interpro:IPR036236|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|interpro:IPR044417|mint:Q9NQV7|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|rcsb pdb:4IJD|rcsb pdb:5EGB|rcsb pdb:5EH2|rcsb pdb:5EI9|rcsb pdb:6NM4|reactome:R-HSA-3214841|reactome:R-HSA-912446 ensembl:ENSG00000218305(gene)|ensembl:ENST00000650262(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005813"(centrosome)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060271"(cilium assembly)|go:"GO:0072686"(mitotic spindle)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR029021|interpro:IPR029260|interpro:IPR044506|mint:A4D256|go:"GO:0000226"(microtubule cytoskeleton organization) - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pj+BI9XftnXTGBd2Q6WY4ptZU8g9606 rogid:tAI9gzD00WlM680vIsxxGQkZRlU9606 rigid:B1C5MdFohTdfnQK2K/uipUJgW0E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQV7 uniprotkb:Q9UBQ7 intact:EBI-17257586|uniprotkb:B4DX22|uniprotkb:Q27Q50|ensembl:ENSP00000296682 intact:EBI-372445|uniprotkb:Q9H3E9|uniprotkb:Q9UKX1|ensembl:ENSP00000313432|uniprotkb:Q5T945|uniprotkb:Q9H636 psi-mi:prdm9_human(display_long)|uniprotkb:Protein-lysine N-methyltransferase PRDM9(gene name synonym)|uniprotkb:PRDM9(gene name)|psi-mi:PRDM9(display_short)|uniprotkb:PFM6(gene name synonym)|uniprotkb:[histone H3]-lysine36 N-trimethyltransferase PRDM9(gene name synonym)|uniprotkb:PR domain zinc finger protein 9(gene name synonym)|uniprotkb:PR domain-containing protein 9(gene name synonym)|uniprotkb:[histone H3]-lysine4 N-trimethyltransferase PRDM9(gene name synonym)|uniprotkb:[histone H3]-lysine9 N-trimethyltransferase PRDM9(gene name synonym)|uniprotkb:[histone H4]-N-methyl-L-lysine20 N-methyltransferase PRDM9(gene name synonym)|uniprotkb:[histone H4]-lysine20 N-methyltransferase PRDM9(gene name synonym) psi-mi:grhpr_human(display_long)|uniprotkb:MSTP035(orf name)|uniprotkb:GRHPR(gene name)|psi-mi:GRHPR(display_short)|uniprotkb:GLXR(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483259|imex:IM-26985-503 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001297143.1|refseq:NP_064612.2|ensembl:ENSG00000164256(gene)|ensembl:ENST00000296682(transcript)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006311"(meiotic gene conversion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007292"(female gamete generation)|go:"GO:0048232"(male gamete generation)|go:"GO:0051567"(histone H3-K9 methylation)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097198"(histone H3-K36 trimethylation)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0097676"(histone H3-K36 dimethylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:0010844"(recombination hotspot binding)|go:"GO:1905437"(positive regulation of histone H3-K4 trimethylation)|go:"GO:1905516"(positive regulation of fertilization)|go:"GO:0010845"(positive regulation of reciprocal meiotic recombination)|go:"GO:1990918"(double-strand break repair involved in meiotic recombination)|go:"GO:0016584"(nucleosome positioning)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR001214(SET)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR003655(Krueppel-associated box-related)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR019041|interpro:IPR036051|interpro:IPR036236|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|interpro:IPR044417|mint:Q9NQV7|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|rcsb pdb:4IJD|rcsb pdb:5EGB|rcsb pdb:5EH2|rcsb pdb:5EI9|rcsb pdb:6NM4|reactome:R-HSA-3214841|reactome:R-HSA-912446 refseq:NP_036335.1|go:"GO:0043648"(dicarboxylic acid metabolic process)|go:"GO:0046487"(glyoxylate metabolic process)|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070402"(NADPH binding)|go:"GO:1902494"(catalytic complex)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029753|interpro:IPR036291|mint:Q9UBQ7|rcsb pdb:2GCG|rcsb pdb:2H1S|rcsb pdb:2Q50|rcsb pdb:2WWR|reactome:R-HSA-389661|ensembl:ENSG00000137106(gene)|ensembl:ENST00000318158(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0007588"(excretion)|go:"GO:0008465"(glycerate dehydrogenase activity)|go:"GO:0016618"(hydroxypyruvate reductase activity)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0030267"("glyoxylate reductase (NADP+) activity")|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0042803"(protein homodimerization activity) - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pj+BI9XftnXTGBd2Q6WY4ptZU8g9606 rogid:qPHrh5I5wHI5MWba4zncz26cUnQ9606 rigid:B1C5MdFohTdfnQK2K/uipUJgW0E false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P55345 uniprotkb:Q5T1J5 intact:EBI-78458|uniprotkb:P78350|uniprotkb:Q9BW15|uniprotkb:Q9UMC2|ensembl:ENSP00000347906|ensembl:ENSP00000380759|ensembl:ENSP00000380760|uniprotkb:Q6FHF0|uniprotkb:Q99781|uniprotkb:Q498Y5|uniprotkb:B7U630|uniprotkb:B7U631|uniprotkb:B7U632|uniprotkb:Q5U7D4 intact:EBI-5325274 psi-mi:anm2_human(display_long)|uniprotkb:PRMT2(gene name)|psi-mi:PRMT2(display_short)|uniprotkb:HMT1(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT2(gene name synonym)|uniprotkb:HRMT1L1(gene name synonym) psi-mi:chch9_human(display_long)|uniprotkb:CHCHD2P9(gene name)|psi-mi:CHCHD2P9(display_short)|uniprotkb:C9orf49(gene name synonym)|uniprotkb:CHCHD9(gene name synonym)|uniprotkb:Coiled-coil-helix-coiled-coil-helix domain-containing 2 pseudogene 9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483280|imex:IM-26985-565 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000160310(gene)|ensembl:ENST00000355680(transcript)|ensembl:ENST00000397637(transcript)|ensembl:ENST00000397638(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048588"(developmental cell growth)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001452(Src homology-3)|interpro:IPR007848(Methyltransferase small)|interpro:IPR025799|interpro:IPR029063|interpro:IPR036028|mint:P55345|rcsb pdb:1X2P|refseq:NP_001526.2|refseq:NP_996845.1|refseq:NP_001273605.1|refseq:NP_001273606.1|refseq:NP_001273607.1|refseq:NP_001229794.1|refseq:NP_001229793.1|refseq:XP_005261168.1|refseq:NP_001229795.1|refseq:XP_006724061.1|refseq:XP_006724063.1 go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|mint:Q5T1J5 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+xna8Cy+5sQWV6hvKfg4rNrQKBw9606 rogid:nxLtnxxMIGeGK2oC3BIhcwkacSs9606 rigid:51rUXMWt0QbjcwpUyQmeFagzxnQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P55345 uniprotkb:Q9UHV9 intact:EBI-78458|uniprotkb:P78350|uniprotkb:Q9BW15|uniprotkb:Q9UMC2|ensembl:ENSP00000347906|ensembl:ENSP00000380759|ensembl:ENSP00000380760|uniprotkb:Q6FHF0|uniprotkb:Q99781|uniprotkb:Q498Y5|uniprotkb:B7U630|uniprotkb:B7U631|uniprotkb:B7U632|uniprotkb:Q5U7D4 intact:EBI-359873|uniprotkb:Q9P0P7|uniprotkb:Q9UN05|ensembl:ENSP00000356989 psi-mi:anm2_human(display_long)|uniprotkb:PRMT2(gene name)|psi-mi:PRMT2(display_short)|uniprotkb:HMT1(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT2(gene name synonym)|uniprotkb:HRMT1L1(gene name synonym) psi-mi:pfd2_human(display_long)|uniprotkb:HSPC231(orf name)|uniprotkb:PFDN2(gene name)|psi-mi:PFDN2(display_short)|uniprotkb:PFD2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483280|imex:IM-26985-565 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000160310(gene)|ensembl:ENST00000355680(transcript)|ensembl:ENST00000397637(transcript)|ensembl:ENST00000397638(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0033142"(progesterone receptor binding)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048588"(developmental cell growth)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001452(Src homology-3)|interpro:IPR007848(Methyltransferase small)|interpro:IPR025799|interpro:IPR029063|interpro:IPR036028|mint:P55345|rcsb pdb:1X2P|refseq:NP_001526.2|refseq:NP_996845.1|refseq:NP_001273605.1|refseq:NP_001273606.1|refseq:NP_001273607.1|refseq:NP_001229794.1|refseq:NP_001229793.1|refseq:XP_005261168.1|refseq:NP_001229795.1|refseq:XP_006724061.1|refseq:XP_006724063.1 refseq:NP_036526.2|refseq:XP_011507926.1|ensembl:ENSG00000143256(gene)|ensembl:ENST00000368010(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|interpro:IPR027235|mint:Q9UHV9|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957|dip:DIP-27557N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+xna8Cy+5sQWV6hvKfg4rNrQKBw9606 rogid:rgr14h3vGyzHxHoNJtlHBQkvhUE9606 rigid:51rUXMWt0QbjcwpUyQmeFagzxnQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60678 uniprotkb:P10412 intact:EBI-2809009|uniprotkb:B4DUC7|uniprotkb:A0A0A0MSN7|ensembl:ENSP00000331879 intact:EBI-358163|uniprotkb:Q4VB25|ensembl:ENSP00000307705 psi-mi:anm3_human(display_long)|uniprotkb:PRMT3(gene name)|psi-mi:PRMT3(display_short)|uniprotkb:HRMT1L3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3(gene name synonym) psi-mi:h14_human(display_long)|uniprotkb:H1-4(gene name)|psi-mi:H1-4(display_short)|uniprotkb:H1F4(gene name synonym)|uniprotkb:HIST1H1E(gene name synonym)|uniprotkb:Histone H1b(gene name synonym)|uniprotkb:Histone H1s-4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483292|imex:IM-26985-505 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005779.1|ensembl:ENSG00000185238(gene)|ensembl:ENST00000331079(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0043022"(ribosome binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1900053"(negative regulation of retinoic acid biosynthetic process)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR025799|interpro:IPR029063|interpro:IPR036236|mint:O60678|rcsb pdb:2FYT|rcsb pdb:3SMQ|rcsb pdb:4HSG|rcsb pdb:4QQN|rcsb pdb:4RYL|reactome:R-HSA-3214858|reactome:R-HSA-8876725 refseq:NP_005312.1|rcsb pdb:6H8P|rcsb pdb:7K5Y|rcsb pdb:7K63|go:"GO:0032564"(dATP binding)|go:"GO:0043531"(ADP binding)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P10412|rcsb pdb:3TZD|rcsb pdb:5JJZ|reactome:R-HSA-140342|reactome:R-HSA-2559584|ensembl:ENSG00000168298(gene)|ensembl:ENST00000304218(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0000792"(heterochromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016208"(AMP binding)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing) - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:XtFHON3qMCvjDhtN8RpXJo9KODU9606 rogid:yT8wBbspLLR8G3DrgpFeWEOPgac9606 rigid:aERQ82h5RmkdPNnu1W0zWEEU9YY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60678 uniprotkb:P01040 intact:EBI-2809009|uniprotkb:B4DUC7|uniprotkb:A0A0A0MSN7|ensembl:ENSP00000331879 intact:EBI-724303|ensembl:ENSP00000264474|uniprotkb:Q6IB90 psi-mi:anm3_human(display_long)|uniprotkb:PRMT3(gene name)|psi-mi:PRMT3(display_short)|uniprotkb:HRMT1L3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3(gene name synonym) psi-mi:cyta_human(display_long)|uniprotkb:Cystatin-AS(gene name synonym)|uniprotkb:Stefin-A(gene name synonym)|uniprotkb:CSTA(gene name)|psi-mi:CSTA(display_short)|uniprotkb:STF1(gene name synonym)|uniprotkb:STFA(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483292|imex:IM-26985-505 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005779.1|ensembl:ENSG00000185238(gene)|ensembl:ENST00000331079(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0043022"(ribosome binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1900053"(negative regulation of retinoic acid biosynthetic process)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR025799|interpro:IPR029063|interpro:IPR036236|mint:O60678|rcsb pdb:2FYT|rcsb pdb:3SMQ|rcsb pdb:4HSG|rcsb pdb:4QQN|rcsb pdb:4RYL|reactome:R-HSA-3214858|reactome:R-HSA-8876725 refseq:NP_005204.1|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR001713(Proteinase inhibitor I25A, stefin A)|mint:P01040|rcsb pdb:1CYU|rcsb pdb:1CYV|rcsb pdb:1DVC|rcsb pdb:1DVD|rcsb pdb:1GD3|rcsb pdb:1GD4|rcsb pdb:1N9J|rcsb pdb:1NB3|rcsb pdb:1NB5|rcsb pdb:3K9M|rcsb pdb:3KFQ|interpro:IPR018073|rcsb pdb:3KSE|reactome:R-HSA-6809371|ensembl:ENSG00000121552(gene)|ensembl:ENST00000264474(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002020"(protease binding)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0045861"(negative regulation of proteolysis) - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:XtFHON3qMCvjDhtN8RpXJo9KODU9606 rogid:SzbpyWUHlOtItIvffzuwhcqFsDI9606 rigid:aERQ82h5RmkdPNnu1W0zWEEU9YY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60678 uniprotkb:P68363 intact:EBI-2809009|uniprotkb:B4DUC7|uniprotkb:A0A0A0MSN7|ensembl:ENSP00000331879 intact:EBI-487083|intact:EBI-1384226|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:Q27I68|ensembl:ENSP00000336799|uniprotkb:Q8WU19 psi-mi:anm3_human(display_long)|uniprotkb:PRMT3(gene name)|psi-mi:PRMT3(display_short)|uniprotkb:HRMT1L3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3(gene name synonym) psi-mi:tba1b_human(display_long)|uniprotkb:TUBA1B(gene name)|psi-mi:TUBA1B(display_short)|uniprotkb:Tubulin alpha-ubiquitous chain(gene name synonym)|uniprotkb:Alpha-tubulin ubiquitous(gene name synonym)|uniprotkb:Tubulin K-alpha-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483292|imex:IM-26985-505 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005779.1|ensembl:ENSG00000185238(gene)|ensembl:ENST00000331079(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0043022"(ribosome binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1900053"(negative regulation of retinoic acid biosynthetic process)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR025799|interpro:IPR029063|interpro:IPR036236|mint:O60678|rcsb pdb:2FYT|rcsb pdb:3SMQ|rcsb pdb:4HSG|rcsb pdb:4QQN|rcsb pdb:4RYL|reactome:R-HSA-3214858|reactome:R-HSA-8876725 refseq:NP_006073.2|ensembl:ENSG00000123416(gene)|ensembl:ENST00000336023(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-983189|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|go:"GO:0045121"(membrane raft)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68363|rcsb pdb:2E4H|rcsb pdb:5IJ0|rcsb pdb:5IJ9|rcsb pdb:5N5N|rcsb pdb:6E7B|rcsb pdb:6E7C|rcsb pdb:6I2I|go:"GO:0051301"(cell division)|rcsb pdb:6J4V|rcsb pdb:6J8O|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|rcsb pdb:6S8L|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9013407|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-2132295|reactome:R-HSA-9668328 - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:XtFHON3qMCvjDhtN8RpXJo9KODU9606 rogid:D4YpuLCXl/S+53qV7P7sF81aARY9606 rigid:aERQ82h5RmkdPNnu1W0zWEEU9YY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60678 uniprotkb:P81605 intact:EBI-2809009|uniprotkb:B4DUC7|uniprotkb:A0A0A0MSN7|ensembl:ENSP00000331879 intact:EBI-395625|uniprotkb:P58461|uniprotkb:A5JHP2|uniprotkb:A5JHP3|uniprotkb:Q53YJ2|ensembl:ENSP00000293371 psi-mi:anm3_human(display_long)|uniprotkb:PRMT3(gene name)|psi-mi:PRMT3(display_short)|uniprotkb:HRMT1L3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3(gene name synonym) psi-mi:dcd_human(display_long)|uniprotkb:AIDD(gene name synonym)|uniprotkb:DSEP(gene name synonym)|uniprotkb:Preproteolysin(gene name synonym)|uniprotkb:DCD(gene name)|psi-mi:DCD(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483292|imex:IM-26985-505 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005779.1|ensembl:ENSG00000185238(gene)|ensembl:ENST00000331079(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0043022"(ribosome binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1900053"(negative regulation of retinoic acid biosynthetic process)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR025799|interpro:IPR029063|interpro:IPR036236|mint:O60678|rcsb pdb:2FYT|rcsb pdb:3SMQ|rcsb pdb:4HSG|rcsb pdb:4QQN|rcsb pdb:4RYL|reactome:R-HSA-3214858|reactome:R-HSA-8876725 refseq:NP_444513.1|refseq:NP_001287783.1|ensembl:ENSG00000161634(gene)|ensembl:ENST00000293371(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008233"(peptidase activity)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR028130|interpro:IPR043557|mint:P81605|rcsb pdb:2KSG|rcsb pdb:2NDK|rcsb pdb:2YMK|rcsb pdb:6SHK|reactome:R-HSA-6803157 - - comment:"author score: 33" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:XtFHON3qMCvjDhtN8RpXJo9KODU9606 rogid:M8PkKVWx98nhtd79ods05mqw8Ls9606 rigid:aERQ82h5RmkdPNnu1W0zWEEU9YY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60678 uniprotkb:P07477 intact:EBI-2809009|uniprotkb:B4DUC7|uniprotkb:A0A0A0MSN7|ensembl:ENSP00000331879 intact:EBI-1222902|uniprotkb:A6NJ71|uniprotkb:Q92955|uniprotkb:Q9HAN4|uniprotkb:Q9HAN5|uniprotkb:Q9HAN6|uniprotkb:Q9HAN7|intact:EBI-1760472|intact:EBI-1965533|uniprotkb:A1A509|uniprotkb:Q5NV57|uniprotkb:Q7M4N3|uniprotkb:Q7M4N4|uniprotkb:B2R5I5|ensembl:ENSP00000308720|ensembl:ENSP00000479217 psi-mi:anm3_human(display_long)|uniprotkb:PRMT3(gene name)|psi-mi:PRMT3(display_short)|uniprotkb:HRMT1L3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3(gene name synonym) psi-mi:try1_human(display_long)|uniprotkb:PRSS1(gene name)|psi-mi:PRSS1(display_short)|uniprotkb:TRP1(gene name synonym)|uniprotkb:TRY1(gene name synonym)|uniprotkb:TRYP1(gene name synonym)|uniprotkb:Trypsin I(gene name synonym)|uniprotkb:Cationic trypsinogen(gene name synonym)|uniprotkb:Serine protease 1(gene name synonym)|uniprotkb:Beta-trypsin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483292|imex:IM-26985-505 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005779.1|ensembl:ENSG00000185238(gene)|ensembl:ENST00000331079(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0043022"(ribosome binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1900053"(negative regulation of retinoic acid biosynthetic process)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR025799|interpro:IPR029063|interpro:IPR036236|mint:O60678|rcsb pdb:2FYT|rcsb pdb:3SMQ|rcsb pdb:4HSG|rcsb pdb:4QQN|rcsb pdb:4RYL|reactome:R-HSA-3214858|reactome:R-HSA-8876725 refseq:NP_002760.1|ensembl:ENSG00000204983(gene)|ensembl:ENSG00000274247(gene)|ensembl:ENST00000311737(transcript)|ensembl:ENST00000616256(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0007586"(digestion)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0072562"(blood microparticle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|mint:P07477|rcsb pdb:1FXY|rcsb pdb:1TRN|rcsb pdb:2RA3|rcsb pdb:4WWY|rcsb pdb:4WXV|reactome:R-HSA-1592389|reactome:R-HSA-196741 - - comment:"author score: 35" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:XtFHON3qMCvjDhtN8RpXJo9KODU9606 rogid:2elS/qMYj0sflxilyWfk3KPtGmo9606 rigid:aERQ82h5RmkdPNnu1W0zWEEU9YY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60678 uniprotkb:P15880 intact:EBI-2809009|uniprotkb:B4DUC7|uniprotkb:A0A0A0MSN7|ensembl:ENSP00000331879 intact:EBI-443446|ensembl:ENSP00000341885|uniprotkb:Q3MIB1|uniprotkb:B2R5G0|uniprotkb:D3DU82 psi-mi:anm3_human(display_long)|uniprotkb:PRMT3(gene name)|psi-mi:PRMT3(display_short)|uniprotkb:HRMT1L3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3(gene name synonym) psi-mi:rs2_human(display_long)|uniprotkb:RPS2(gene name)|psi-mi:RPS2(display_short)|uniprotkb:RPS4(gene name synonym)|uniprotkb:40S ribosomal protein S4(gene name synonym)|uniprotkb:Protein LLRep3(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483292|imex:IM-26985-505 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005779.1|ensembl:ENSG00000185238(gene)|ensembl:ENST00000331079(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0043022"(ribosome binding)|go:"GO:0046872"(metal ion binding)|go:"GO:1900053"(negative regulation of retinoic acid biosynthetic process)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR025799|interpro:IPR029063|interpro:IPR036236|mint:O60678|rcsb pdb:2FYT|rcsb pdb:3SMQ|rcsb pdb:4HSG|rcsb pdb:4QQN|rcsb pdb:4RYL|reactome:R-HSA-3214858|reactome:R-HSA-8876725 interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|rcsb pdb:6OLG|rcsb pdb:6OLI|interpro:IPR018192|rcsb pdb:6OLZ|interpro:IPR020568|mint:P15880|rcsb pdb:4UG0|rcsb pdb:6OM0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6EK0|rcsb pdb:6G18|rcsb pdb:6XA1|rcsb pdb:6G4S|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6G5H|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7JQB|rcsb pdb:7JQC|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-3214858|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-8876725|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:7A09|ensembl:ENSG00000140988(gene)|ensembl:ENST00000343262(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0045296"(cadherin binding)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000851(Ribosomal protein S5)|interpro:IPR005324(Ribosomal protein S5, C-terminal)|interpro:IPR005711(Ribosomal protein S5, eukaryotic/archaeal)|interpro:IPR013810(Ribosomal protein S5, N-terminal)|refseq:NP_002943.2 - - comment:"author score: 41" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:XtFHON3qMCvjDhtN8RpXJo9KODU9606 rogid:JUr2Y3cGk00S8KaTVPymshfaHhc9606 rigid:aERQ82h5RmkdPNnu1W0zWEEU9YY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3Y4 uniprotkb:Q68G74 intact:EBI-3397474|ensembl:ENSP00000302327|uniprotkb:A7Y2D6 intact:EBI-8474075|intact:MINT-8417689|uniprotkb:E9PGE3|ensembl:ENSP00000294638 psi-mi:pygo1_human(display_long)|uniprotkb:PYGO1(gene name)|psi-mi:PYGO1(display_short) psi-mi:lhx8_human(display_long)|uniprotkb:LHX8(gene name)|psi-mi:LHX8(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483316|imex:IM-26985-267 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000171016(gene)|ensembl:ENST00000302000(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q9Y3Y4|rcsb pdb:2VP7|rcsb pdb:2VPB|rcsb pdb:2VPD|rcsb pdb:2VPE|rcsb pdb:2VPG|reactome:R-HSA-201722|reactome:R-HSA-3769402|refseq:XP_011519748.1|refseq:NP_056432.1|refseq:NP_001317255.1 refseq:NP_001243043.1|refseq:NP_001001933.1|ensembl:ENSG00000162624(gene)|ensembl:ENST00000294638(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001674"(female germ cell nucleus)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007611"(learning or memory)|go:"GO:0008585"(female gonad development)|go:"GO:0021884"(forebrain neuron development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:Q68G74 - - comment:mint|comment:homomint|comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:mJqxowcHq31gLHVE/o5tOX29qAI9606 rogid:L7W2mSN0r9Fl/94L/D2dL5mGHz89606 rigid:ZcoTGGAL1GzfIydMCQJ0iraN2Fs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3Y4 uniprotkb:Q969G2 intact:EBI-3397474|ensembl:ENSP00000302327|uniprotkb:A7Y2D6 intact:EBI-2865388|uniprotkb:Q8NHM1|uniprotkb:Q969W2|uniprotkb:Q8TCJ1|uniprotkb:Q8NHE0|uniprotkb:Q8WWX2|ensembl:ENSP00000263726 psi-mi:pygo1_human(display_long)|uniprotkb:PYGO1(gene name)|psi-mi:PYGO1(display_short) psi-mi:lhx4_human(display_long)|uniprotkb:LHX4(gene name)|psi-mi:LHX4(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483316|imex:IM-26985-267 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000171016(gene)|ensembl:ENST00000302000(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q9Y3Y4|rcsb pdb:2VP7|rcsb pdb:2VPB|rcsb pdb:2VPD|rcsb pdb:2VPE|rcsb pdb:2VPG|reactome:R-HSA-201722|reactome:R-HSA-3769402|refseq:XP_011519748.1|refseq:NP_056432.1|refseq:NP_001317255.1 refseq:NP_203129.1|dip:DIP-29454N|ensembl:ENSG00000121454(gene)|ensembl:ENST00000263726(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001890"(placenta development)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0021526"(medial motor column neuron differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:Q969G2|rcsb pdb:5HOD|reactome:R-HSA-9010553 - - crc64:6499F38E78B79FD1|comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:mJqxowcHq31gLHVE/o5tOX29qAI9606 rogid:dCB3WgIBMdi0nNvaCFaioh+F9sw9606 rigid:ZcoTGGAL1GzfIydMCQJ0iraN2Fs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3Y4 uniprotkb:P50458 intact:EBI-3397474|ensembl:ENSP00000302327|uniprotkb:A7Y2D6 intact:EBI-12179869|ensembl:ENSP00000362717|uniprotkb:O95860|uniprotkb:Q52M57|uniprotkb:Q8N1Z3 psi-mi:pygo1_human(display_long)|uniprotkb:PYGO1(gene name)|psi-mi:PYGO1(display_short) psi-mi:lhx2_human(display_long)|uniprotkb:LHX2(gene name)|psi-mi:LHX2(display_short)|uniprotkb:LH2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483316|imex:IM-26985-267 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000171016(gene)|ensembl:ENST00000302000(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q9Y3Y4|rcsb pdb:2VP7|rcsb pdb:2VPB|rcsb pdb:2VPD|rcsb pdb:2VPE|rcsb pdb:2VPG|reactome:R-HSA-201722|reactome:R-HSA-3769402|refseq:XP_011519748.1|refseq:NP_056432.1|refseq:NP_001317255.1 ensembl:ENSG00000106689(gene)|ensembl:ENST00000373615(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001843"(neural tube closure)|go:"GO:0001942"(hair follicle development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007411"(axon guidance)|go:"GO:0007498"(mesoderm development)|go:"GO:0009953"(dorsal/ventral pattern formation)|go:"GO:0021772"(olfactory bulb development)|go:"GO:0021978"(telencephalon regionalization)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030182"(neuron differentiation)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048675"(axon extension)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P50458|reactome:R-HSA-9010553|refseq:NP_004780.3 - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:mJqxowcHq31gLHVE/o5tOX29qAI9606 rogid:LgQI6F9VG7krrf3LhrsNGkRkKBc9606 rigid:ZcoTGGAL1GzfIydMCQJ0iraN2Fs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3Y4 uniprotkb:P07478 intact:EBI-3397474|ensembl:ENSP00000302327|uniprotkb:A7Y2D6 intact:EBI-14061700|ensembl:ENSP00000487952|ensembl:ENSP00000488338 psi-mi:pygo1_human(display_long)|uniprotkb:PYGO1(gene name)|psi-mi:PYGO1(display_short) psi-mi:try2_human(display_long)|uniprotkb:PRSS2(gene name)|psi-mi:PRSS2(display_short)|uniprotkb:TRY2(gene name synonym)|uniprotkb:TRYP2(gene name synonym)|uniprotkb:Anionic trypsinogen(gene name synonym)|uniprotkb:Serine protease 2(gene name synonym)|uniprotkb:Trypsin II(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483316|imex:IM-26985-267 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000171016(gene)|ensembl:ENST00000302000(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q9Y3Y4|rcsb pdb:2VP7|rcsb pdb:2VPB|rcsb pdb:2VPD|rcsb pdb:2VPE|rcsb pdb:2VPG|reactome:R-HSA-201722|reactome:R-HSA-3769402|refseq:XP_011519748.1|refseq:NP_056432.1|refseq:NP_001317255.1 go:"GO:0007586"(digestion)|go:"GO:0008236"(serine-type peptidase activity)|ensembl:ENSG00000275896(gene)|ensembl:ENSG00000282049(gene)|ensembl:ENST00000539842(transcript)|ensembl:ENST00000632112(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030574"(collagen catabolic process)|go:"GO:0031012"(extracellular matrix)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045785"(positive regulation of cell adhesion)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|mint:P07478|reactome:R-HSA-1442490|reactome:R-HSA-1462054|reactome:R-HSA-1592389|reactome:R-HSA-6798695|reactome:R-HSA-6803157|refseq:NP_002761.1 - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:mJqxowcHq31gLHVE/o5tOX29qAI9606 rogid:xP8rgMfzospYU202s9zSfkgHHzM9606 rigid:ZcoTGGAL1GzfIydMCQJ0iraN2Fs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3Y4 uniprotkb:Q9BWG4 intact:EBI-3397474|ensembl:ENSP00000302327|uniprotkb:A7Y2D6 intact:EBI-744719|ensembl:ENSP00000270061|uniprotkb:Q9BWW5 psi-mi:pygo1_human(display_long)|uniprotkb:PYGO1(gene name)|psi-mi:PYGO1(display_short) psi-mi:ssbp4_human(display_long)|uniprotkb:SSBP4(gene name)|psi-mi:SSBP4(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483316|imex:IM-26985-267 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000171016(gene)|ensembl:ENST00000302000(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q9Y3Y4|rcsb pdb:2VP7|rcsb pdb:2VPB|rcsb pdb:2VPD|rcsb pdb:2VPE|rcsb pdb:2VPG|reactome:R-HSA-201722|reactome:R-HSA-3769402|refseq:XP_011519748.1|refseq:NP_056432.1|refseq:NP_001317255.1 ensembl:ENSG00000130511(gene)|ensembl:ENST00000270061(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9BWG4|refseq:NP_001009998.1|refseq:NP_116016.1 - - comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:mJqxowcHq31gLHVE/o5tOX29qAI9606 rogid:c0T7Xjz4MbjSZpCzJlpGVFbFYy89606 rigid:ZcoTGGAL1GzfIydMCQJ0iraN2Fs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3Y4 uniprotkb:P61371 intact:EBI-3397474|ensembl:ENSP00000302327|uniprotkb:A7Y2D6 intact:EBI-3906896|uniprotkb:P47894|uniprotkb:P20663|ensembl:ENSP00000230658 psi-mi:pygo1_human(display_long)|uniprotkb:PYGO1(gene name)|psi-mi:PYGO1(display_short) psi-mi:isl1_human(display_long)|uniprotkb:ISL1(gene name)|psi-mi:ISL1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483316|imex:IM-26985-267 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000171016(gene)|ensembl:ENST00000302000(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q9Y3Y4|rcsb pdb:2VP7|rcsb pdb:2VPB|rcsb pdb:2VPD|rcsb pdb:2VPE|rcsb pdb:2VPG|reactome:R-HSA-201722|reactome:R-HSA-3769402|refseq:XP_011519748.1|refseq:NP_056432.1|refseq:NP_001317255.1 refseq:NP_002193.2|ensembl:ENSP00000230658|ensembl:ENSG00000016082(gene)|ensembl:ENST00000230658(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003215"(cardiac right ventricle morphogenesis)|go:"GO:0003266"(regulation of secondary heart field cardioblast proliferation)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007409"(axonogenesis)|go:"GO:0007507"(heart development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0021520"(spinal cord motor neuron cell fate specification)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0021524"(visceral motor neuron differentiation)|go:"GO:0021559"(trigeminal nerve development)|go:"GO:0021983"(pituitary gland development)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0031016"(pancreas development)|go:"GO:0031103"(axon regeneration)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048762"(mesenchymal cell differentiation)|go:"GO:0048880"(sensory system development)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0048936"(peripheral nervous system neuron axonogenesis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060037"(pharyngeal system development)|go:"GO:0060379"(cardiac muscle cell myoblast differentiation)|go:"GO:0060384"(innervation)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060913"(cardiac cell fate determination)|go:"GO:0060931"(sinoatrial node cell development)|go:"GO:0032725"(positive regulation of granulocyte macrophage colony-stimulating factor production)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0032730"(positive regulation of interleukin-1 alpha production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0032735"(positive regulation of interleukin-12 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071657"(positive regulation of granulocyte colony-stimulating factor production)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1901258"(positive regulation of macrophage colony-stimulating factor production)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:P61371|reactome:R-HSA-400511|reactome:R-HSA-9010553 - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:mJqxowcHq31gLHVE/o5tOX29qAI9606 rogid:1eir7wLzkoqlwl4AfQuBtjjiyd09606 rigid:ZcoTGGAL1GzfIydMCQJ0iraN2Fs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3Y4 uniprotkb:Q96A47 intact:EBI-3397474|ensembl:ENSP00000302327|uniprotkb:A7Y2D6 intact:EBI-18560216|uniprotkb:B3KM37|ensembl:ENSP00000290759 psi-mi:pygo1_human(display_long)|uniprotkb:PYGO1(gene name)|psi-mi:PYGO1(display_short) psi-mi:isl2_human(display_long)|uniprotkb:ISL2(gene name)|psi-mi:ISL2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483316|imex:IM-26985-267 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000171016(gene)|ensembl:ENST00000302000(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q9Y3Y4|rcsb pdb:2VP7|rcsb pdb:2VPB|rcsb pdb:2VPD|rcsb pdb:2VPE|rcsb pdb:2VPG|reactome:R-HSA-201722|reactome:R-HSA-3769402|refseq:XP_011519748.1|refseq:NP_056432.1|refseq:NP_001317255.1 refseq:NP_665804.1|ensembl:ENSG00000159556(gene)|ensembl:ENST00000290759(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007409"(axonogenesis)|go:"GO:0021520"(spinal cord motor neuron cell fate specification)|go:"GO:0021524"(visceral motor neuron differentiation)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0046872"(metal ion binding)|go:"GO:0048665"(neuron fate specification)|go:"GO:0048666"(neuron development)|go:"GO:0048935"(peripheral nervous system neuron development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|mint:Q96A47|go:"GO:0045665"(negative regulation of neuron differentiation) - - comment:"author score: 46" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:mJqxowcHq31gLHVE/o5tOX29qAI9606 rogid:TuRrmmyJy7Dk+0fn1BDmkcmUf1A9606 rigid:ZcoTGGAL1GzfIydMCQJ0iraN2Fs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3Y4 uniprotkb:Q86UU0 intact:EBI-3397474|ensembl:ENSP00000302327|uniprotkb:A7Y2D6 intact:EBI-1385618|uniprotkb:A1A4C1|uniprotkb:Q6ZWJ0|uniprotkb:Q6ZWK2|uniprotkb:Q67FY1|ensembl:ENSP00000335320|ensembl:ENSP00000507778 psi-mi:pygo1_human(display_long)|uniprotkb:PYGO1(gene name)|psi-mi:PYGO1(display_short) psi-mi:bcl9l_human(display_long)|uniprotkb:BCL9L(gene name)|psi-mi:BCL9L(display_short)|uniprotkb:DLNB11(gene name synonym)|uniprotkb:Protein BCL9-2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483316|imex:IM-26985-267 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000171016(gene)|ensembl:ENST00000302000(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q9Y3Y4|rcsb pdb:2VP7|rcsb pdb:2VPB|rcsb pdb:2VPD|rcsb pdb:2VPE|rcsb pdb:2VPG|reactome:R-HSA-201722|reactome:R-HSA-3769402|refseq:XP_011519748.1|refseq:NP_056432.1|refseq:NP_001317255.1 refseq:XP_006718878.1|refseq:NP_872363.1|refseq:XP_005271568.1|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015668(B Cell Lymphoma 9)|interpro:IPR024670|mint:Q86UU0|rcsb pdb:2XB1|rcsb pdb:4UP0|rcsb pdb:4UP5|reactome:R-HSA-201722|reactome:R-HSA-3769402|ensembl:ENSG00000186174(gene)|ensembl:ENST00000334801(transcript)|ensembl:ENST00000683865(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008013"(beta-catenin binding) - - comment:"author score: 48" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:mJqxowcHq31gLHVE/o5tOX29qAI9606 rogid:P+OLquMM+rYlekJdbUA4BuFP5xs9606 rigid:ZcoTGGAL1GzfIydMCQJ0iraN2Fs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3Y4 uniprotkb:Q9Y5N6 intact:EBI-3397474|ensembl:ENSP00000302327|uniprotkb:A7Y2D6 intact:EBI-374840|ensembl:ENSP00000219097|uniprotkb:B3KN89 psi-mi:pygo1_human(display_long)|uniprotkb:PYGO1(gene name)|psi-mi:PYGO1(display_short) psi-mi:orc6_human(display_long)|uniprotkb:ORC6(gene name)|psi-mi:ORC6(display_short)|uniprotkb:ORC6L(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483316|imex:IM-26985-267 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000171016(gene)|ensembl:ENST00000302000(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q9Y3Y4|rcsb pdb:2VP7|rcsb pdb:2VPB|rcsb pdb:2VPD|rcsb pdb:2VPE|rcsb pdb:2VPG|reactome:R-HSA-201722|reactome:R-HSA-3769402|refseq:XP_011519748.1|refseq:NP_056432.1|refseq:NP_001317255.1 ensembl:ENSG00000091651(gene)|ensembl:ENST00000219097(transcript)|go:"GO:0000808"(origin recognition complex)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0016020"(membrane)|go:"GO:0051782"(negative regulation of cell division)|interpro:IPR008721(Origin recognition complex subunit 6)|interpro:IPR020529|mint:Q9Y5N6|rcsb pdb:3M03|rcsb pdb:6KVG|reactome:R-HSA-113507|reactome:R-HSA-176187|reactome:R-HSA-68616|reactome:R-HSA-68689|reactome:R-HSA-68827|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|refseq:NP_055136.1|dip:DIP-29692N - - comment:"author score: 53" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:mJqxowcHq31gLHVE/o5tOX29qAI9606 rogid:WElR6cWK58+oULzC4OgHBDVgikc9606 rigid:ZcoTGGAL1GzfIydMCQJ0iraN2Fs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3Y4 uniprotkb:P61968 intact:EBI-3397474|ensembl:ENSP00000302327|uniprotkb:A7Y2D6 intact:EBI-2798728|uniprotkb:O00158|uniprotkb:O88894|uniprotkb:D3DT23|ensembl:ENSP00000359573|ensembl:ENSP00000359575 psi-mi:pygo1_human(display_long)|uniprotkb:PYGO1(gene name)|psi-mi:PYGO1(display_short) psi-mi:lmo4_human(display_long)|uniprotkb:Breast tumor autoantigen(gene name synonym)|uniprotkb:LIM domain only protein 4(gene name synonym)|uniprotkb:LMO4(gene name)|psi-mi:LMO4(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483316|imex:IM-26985-267 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000171016(gene)|ensembl:ENST00000302000(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q9Y3Y4|rcsb pdb:2VP7|rcsb pdb:2VPB|rcsb pdb:2VPD|rcsb pdb:2VPE|rcsb pdb:2VPG|reactome:R-HSA-201722|reactome:R-HSA-3769402|refseq:XP_011519748.1|refseq:NP_056432.1|refseq:NP_001317255.1 refseq:NP_006760.1|refseq:XP_005271348.1|ensembl:ENSG00000143013(gene)|ensembl:ENST00000370542(transcript)|ensembl:ENST00000370544(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0008134"(transcription factor binding)|go:"GO:0021514"(ventral spinal cord interneuron differentiation)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0021527"(spinal cord association neuron differentiation)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0042659"(regulation of cell fate specification)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048538"(thymus development)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR001781(Zinc finger, LIM-type)|mint:P61968|go:"GO:0050865"(regulation of cell activation)|rcsb pdb:2L4Z|dip:DIP-41414N - - crc64:C8AC295144AD7787|comment:"author score: 60" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:mJqxowcHq31gLHVE/o5tOX29qAI9606 rogid:A6F+R5tMkoNqN0nAuwTjOoVnjQE9606 rigid:ZcoTGGAL1GzfIydMCQJ0iraN2Fs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3Y4 uniprotkb:P81877 intact:EBI-3397474|ensembl:ENSP00000302327|uniprotkb:A7Y2D6 intact:EBI-748077|uniprotkb:Q8N2Q2|uniprotkb:Q9BWW6|uniprotkb:Q9Y4T7|uniprotkb:B7Z2L9|uniprotkb:E9PDA8|uniprotkb:B2R5W1|uniprotkb:B7Z1J2|uniprotkb:B7Z665|uniprotkb:D6RH18|uniprotkb:E9PB74|intact:EBI-28967061|ensembl:ENSP00000322977 psi-mi:pygo1_human(display_long)|uniprotkb:PYGO1(gene name)|psi-mi:PYGO1(display_short) psi-mi:ssbp2_human(display_long)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein 2(gene name synonym)|uniprotkb:SSBP2(gene name)|psi-mi:SSBP2(display_short)|uniprotkb:SSDP2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483316|imex:IM-26985-267 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000171016(gene)|ensembl:ENST00000302000(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q9Y3Y4|rcsb pdb:2VP7|rcsb pdb:2VPB|rcsb pdb:2VPD|rcsb pdb:2VPE|rcsb pdb:2VPG|reactome:R-HSA-201722|reactome:R-HSA-3769402|refseq:XP_011519748.1|refseq:NP_056432.1|refseq:NP_001317255.1 ensembl:ENSP00000322977|ensembl:ENST00000505980|ensembl:ENSP00000423969|ensembl:ENST00000509053|ensembl:ENSP00000422961|ensembl:ENST00000514493|ensembl:ENSP00000426183|ensembl:ENST00000515395|ensembl:ENSP00000424657|refseq:NP_001243661.1|refseq:NP_036578.2|refseq:NP_001243665.1|refseq:NP_001243663.1|refseq:NP_001243664.1|refseq:NP_001243662.1|ensembl:ENSG00000145687(gene)|ensembl:ENST00000320672(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:P81877|rcsb pdb:6IWV|rcsb pdb:6TYD|dip:DIP-29459N - - comment:"author score: 89" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:mJqxowcHq31gLHVE/o5tOX29qAI9606 rogid:CMmZPTurp1G6Y2q7GP/pTMlFM549606 rigid:ZcoTGGAL1GzfIydMCQJ0iraN2Fs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3Y4 uniprotkb:O00512 intact:EBI-3397474|ensembl:ENSP00000302327|uniprotkb:A7Y2D6 intact:EBI-533127|uniprotkb:Q5T489|intact:EBI-28969406|ensembl:ENSP00000234739 psi-mi:pygo1_human(display_long)|uniprotkb:PYGO1(gene name)|psi-mi:PYGO1(display_short) psi-mi:bcl9_human(display_long)|uniprotkb:Protein legless homolog(gene name synonym)|uniprotkb:BCL9(gene name)|psi-mi:BCL9(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483316|imex:IM-26985-267 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000171016(gene)|ensembl:ENST00000302000(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q9Y3Y4|rcsb pdb:2VP7|rcsb pdb:2VPB|rcsb pdb:2VPD|rcsb pdb:2VPE|rcsb pdb:2VPG|reactome:R-HSA-201722|reactome:R-HSA-3769402|refseq:XP_011519748.1|refseq:NP_056432.1|refseq:NP_001317255.1 ensembl:ENSP00000234739|ensembl:ENSG00000116128(gene)|ensembl:ENST00000234739(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0014908"(myotube differentiation involved in skeletal muscle regeneration)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015668(B Cell Lymphoma 9)|interpro:IPR024670|mint:O00512|rcsb pdb:2GL7|rcsb pdb:2VP7|rcsb pdb:2VPB|rcsb pdb:2VPD|rcsb pdb:2VPE|rcsb pdb:2VPG|rcsb pdb:3SL9|reactome:R-HSA-201722|reactome:R-HSA-3769402|refseq:NP_004317.2|refseq:XP_005273028.1 - - comment:"author score: 95" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:mJqxowcHq31gLHVE/o5tOX29qAI9606 rogid:RCCh4ZkVE2BITRjPSL38IKnaaAk9606 rigid:ZcoTGGAL1GzfIydMCQJ0iraN2Fs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3Y4 uniprotkb:Q9BWW4 intact:EBI-3397474|ensembl:ENSP00000302327|uniprotkb:A7Y2D6 intact:EBI-2902395|uniprotkb:A8K0A9|uniprotkb:Q5T860|uniprotkb:Q5T861|uniprotkb:Q9BTM0|uniprotkb:Q9BWW3|ensembl:ENSP00000479674 psi-mi:pygo1_human(display_long)|uniprotkb:PYGO1(gene name)|psi-mi:PYGO1(display_short) psi-mi:ssbp3_human(display_long)|uniprotkb:SSBP3(gene name)|psi-mi:SSBP3(display_short)|uniprotkb:SSDP(gene name synonym)|uniprotkb:SSDP1(gene name synonym)|uniprotkb:Sequence-specific single-stranded-DNA-binding protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483316|imex:IM-26985-267 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000171016(gene)|ensembl:ENST00000302000(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q9Y3Y4|rcsb pdb:2VP7|rcsb pdb:2VPB|rcsb pdb:2VPD|rcsb pdb:2VPE|rcsb pdb:2VPG|reactome:R-HSA-201722|reactome:R-HSA-3769402|refseq:XP_011519748.1|refseq:NP_056432.1|refseq:NP_001317255.1 refseq:NP_001009955.1|refseq:NP_060540.2|refseq:NP_663768.1|dip:DIP-48897N|ensembl:ENSG00000157216(gene)|ensembl:ENST00000610401(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR006594(LisH dimerisation motif)|interpro:IPR008116(Sequence-specific single-strand DNA-binding protein)|mint:Q9BWW4 - - crc64:DBBB169D4EE10536|comment:"author score: 96" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:mJqxowcHq31gLHVE/o5tOX29qAI9606 rogid:GD7FO6kR/5WawTNP0MaDcmIf7f49606 rigid:ZcoTGGAL1GzfIydMCQJ0iraN2Fs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y3Y4 uniprotkb:Q86U70 intact:EBI-3397474|ensembl:ENSP00000302327|uniprotkb:A7Y2D6 intact:EBI-677177|uniprotkb:O75479|uniprotkb:O96010|uniprotkb:Q1EQX1|uniprotkb:Q9UGM4|uniprotkb:B4DUC4|ensembl:ENSP00000501277 psi-mi:pygo1_human(display_long)|uniprotkb:PYGO1(gene name)|psi-mi:PYGO1(display_short) psi-mi:ldb1_human(display_long)|uniprotkb:Nuclear LIM interactor(gene name synonym)|uniprotkb:Carboxyl-terminal LIM domain-binding protein 2(gene name synonym)|uniprotkb:LIM domain-binding factor CLIM2(gene name synonym)|uniprotkb:LDB1(gene name)|psi-mi:LDB1(display_short)|uniprotkb:CLIM2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483316|imex:IM-26985-267 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000171016(gene)|ensembl:ENST00000302000(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060070"(canonical Wnt signaling pathway)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q9Y3Y4|rcsb pdb:2VP7|rcsb pdb:2VPB|rcsb pdb:2VPD|rcsb pdb:2VPE|rcsb pdb:2VPG|reactome:R-HSA-201722|reactome:R-HSA-3769402|refseq:XP_011519748.1|refseq:NP_056432.1|refseq:NP_001317255.1 refseq:NP_001106878.1|refseq:NP_003884.1|dip:DIP-31826N|ensembl:ENSG00000198728(gene)|ensembl:ENST00000673968(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000972"(transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001942"(hair follicle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007399"(nervous system development)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0021702"(cerebellar Purkinje cell differentiation)|go:"GO:0022607"(cellular component assembly)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043549"(regulation of kinase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0043973"(histone H3-K4 acetylation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048382"(mesendoderm development)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR029005|interpro:IPR030167|interpro:IPR041363|mint:Q86U70|rcsb pdb:2XJY|rcsb pdb:2XJZ|rcsb pdb:2YPA|rcsb pdb:6TYD|reactome:R-HSA-8939236|reactome:R-HSA-9010553 - - comment:"author score: 127" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:mJqxowcHq31gLHVE/o5tOX29qAI9606 rogid:qvQKQuFDKim15gEBFj6MnxR6lTc9606 rigid:ZcoTGGAL1GzfIydMCQJ0iraN2Fs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BRQ0 uniprotkb:P60174 intact:EBI-932471|uniprotkb:Q8WYZ4|uniprotkb:Q96CY2|intact:EBI-28967415|ensembl:ENSP00000357442 intact:EBI-717475|uniprotkb:D3DUS9|uniprotkb:P00938|uniprotkb:Q6IS07|uniprotkb:Q8WWD0|uniprotkb:Q96AG5|uniprotkb:Q6FHP9|uniprotkb:B7Z5D8|ensembl:ENSP00000379933 psi-mi:pygo2_human(display_long)|uniprotkb:PYGO2(gene name)|psi-mi:PYGO2(display_short)|uniprotkb:PP7910(orf name) psi-mi:tpis_human(display_long)|uniprotkb:Triose-phosphate isomerase(gene name synonym)|uniprotkb:TPI1(gene name)|psi-mi:TPI1(display_short)|uniprotkb:TPI(gene name synonym)|uniprotkb:Methylglyoxal synthase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483364|imex:IM-26985-127 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000357442|refseq:NP_612157.1|ensembl:ENSG00000163348(gene)|ensembl:ENST00000368457(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0007420"(brain development)|go:"GO:0030879"(mammary gland development)|go:"GO:0033599"(regulation of mammary gland epithelial cell proliferation)|go:"GO:0035034"(histone acetyltransferase regulator activity)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042393"(histone binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048589"(developmental growth)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q9BRQ0|rcsb pdb:2XB1|rcsb pdb:4UP0|rcsb pdb:4UP5|reactome:R-HSA-201722|reactome:R-HSA-3769402 refseq:NP_000356.1|refseq:NP_001152759.1|refseq:NP_001244955.1|ensembl:ENSG00000111669(gene)|ensembl:ENST00000396705(transcript)|go:"GO:0004807"(triose-phosphate isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0008929"(methylglyoxal synthase activity)|go:"GO:0019242"(methylglyoxal biosynthetic process)|go:"GO:0019563"(glycerol catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046166"(glyceraldehyde-3-phosphate biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000652(Triosephosphate isomerase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR020861|interpro:IPR022896|interpro:IPR035990|mint:P60174|rcsb pdb:1HTI|rcsb pdb:1KLG|rcsb pdb:1KLU|rcsb pdb:1WYI|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2JK2|rcsb pdb:2VOM|rcsb pdb:4BR1|rcsb pdb:4E41|rcsb pdb:4POC|rcsb pdb:4POD|rcsb pdb:4UNK|rcsb pdb:4UNL|rcsb pdb:4ZVJ|rcsb pdb:6C2G|rcsb pdb:6D43|rcsb pdb:6NLH|rcsb pdb:6UP1|rcsb pdb:6UP5|rcsb pdb:6UP8|rcsb pdb:6UPF|reactome:R-HSA-70171|reactome:R-HSA-70263 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:pnjkTQxG5O0yk8WfuSd0MMsZ3dU9606 rogid:FaLt6wGI1Bz2Z81gX35p7sOiMbE9606 rigid:E1koKbqoYSOO4FjUhIK1VX9fsso false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BRQ0 uniprotkb:Q9UBQ7 intact:EBI-932471|uniprotkb:Q8WYZ4|uniprotkb:Q96CY2|intact:EBI-28967415|ensembl:ENSP00000357442 intact:EBI-372445|uniprotkb:Q9H3E9|uniprotkb:Q9UKX1|ensembl:ENSP00000313432|uniprotkb:Q5T945|uniprotkb:Q9H636 psi-mi:pygo2_human(display_long)|uniprotkb:PYGO2(gene name)|psi-mi:PYGO2(display_short)|uniprotkb:PP7910(orf name) psi-mi:grhpr_human(display_long)|uniprotkb:MSTP035(orf name)|uniprotkb:GRHPR(gene name)|psi-mi:GRHPR(display_short)|uniprotkb:GLXR(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483364|imex:IM-26985-127 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000357442|refseq:NP_612157.1|ensembl:ENSG00000163348(gene)|ensembl:ENST00000368457(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0007420"(brain development)|go:"GO:0030879"(mammary gland development)|go:"GO:0033599"(regulation of mammary gland epithelial cell proliferation)|go:"GO:0035034"(histone acetyltransferase regulator activity)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042393"(histone binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048589"(developmental growth)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q9BRQ0|rcsb pdb:2XB1|rcsb pdb:4UP0|rcsb pdb:4UP5|reactome:R-HSA-201722|reactome:R-HSA-3769402 refseq:NP_036335.1|go:"GO:0043648"(dicarboxylic acid metabolic process)|go:"GO:0046487"(glyoxylate metabolic process)|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070402"(NADPH binding)|go:"GO:1902494"(catalytic complex)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029753|interpro:IPR036291|mint:Q9UBQ7|rcsb pdb:2GCG|rcsb pdb:2H1S|rcsb pdb:2Q50|rcsb pdb:2WWR|reactome:R-HSA-389661|ensembl:ENSG00000137106(gene)|ensembl:ENST00000318158(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0007588"(excretion)|go:"GO:0008465"(glycerate dehydrogenase activity)|go:"GO:0016618"(hydroxypyruvate reductase activity)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0030267"("glyoxylate reductase (NADP+) activity")|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0042803"(protein homodimerization activity) - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:pnjkTQxG5O0yk8WfuSd0MMsZ3dU9606 rogid:qPHrh5I5wHI5MWba4zncz26cUnQ9606 rigid:E1koKbqoYSOO4FjUhIK1VX9fsso false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BRQ0 uniprotkb:Q86UU0 intact:EBI-932471|uniprotkb:Q8WYZ4|uniprotkb:Q96CY2|intact:EBI-28967415|ensembl:ENSP00000357442 intact:EBI-1385618|uniprotkb:A1A4C1|uniprotkb:Q6ZWJ0|uniprotkb:Q6ZWK2|uniprotkb:Q67FY1|ensembl:ENSP00000335320|ensembl:ENSP00000507778 psi-mi:pygo2_human(display_long)|uniprotkb:PYGO2(gene name)|psi-mi:PYGO2(display_short)|uniprotkb:PP7910(orf name) psi-mi:bcl9l_human(display_long)|uniprotkb:BCL9L(gene name)|psi-mi:BCL9L(display_short)|uniprotkb:DLNB11(gene name synonym)|uniprotkb:Protein BCL9-2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483364|imex:IM-26985-127 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000357442|refseq:NP_612157.1|ensembl:ENSG00000163348(gene)|ensembl:ENST00000368457(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0007420"(brain development)|go:"GO:0030879"(mammary gland development)|go:"GO:0033599"(regulation of mammary gland epithelial cell proliferation)|go:"GO:0035034"(histone acetyltransferase regulator activity)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042393"(histone binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048589"(developmental growth)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q9BRQ0|rcsb pdb:2XB1|rcsb pdb:4UP0|rcsb pdb:4UP5|reactome:R-HSA-201722|reactome:R-HSA-3769402 refseq:XP_006718878.1|refseq:NP_872363.1|refseq:XP_005271568.1|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015668(B Cell Lymphoma 9)|interpro:IPR024670|mint:Q86UU0|rcsb pdb:2XB1|rcsb pdb:4UP0|rcsb pdb:4UP5|reactome:R-HSA-201722|reactome:R-HSA-3769402|ensembl:ENSG00000186174(gene)|ensembl:ENST00000334801(transcript)|ensembl:ENST00000683865(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008013"(beta-catenin binding) - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:pnjkTQxG5O0yk8WfuSd0MMsZ3dU9606 rogid:P+OLquMM+rYlekJdbUA4BuFP5xs9606 rigid:E1koKbqoYSOO4FjUhIK1VX9fsso false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BRQ0 uniprotkb:O00512 intact:EBI-932471|uniprotkb:Q8WYZ4|uniprotkb:Q96CY2|intact:EBI-28967415|ensembl:ENSP00000357442 intact:EBI-533127|uniprotkb:Q5T489|intact:EBI-28969406|ensembl:ENSP00000234739 psi-mi:pygo2_human(display_long)|uniprotkb:PYGO2(gene name)|psi-mi:PYGO2(display_short)|uniprotkb:PP7910(orf name) psi-mi:bcl9_human(display_long)|uniprotkb:Protein legless homolog(gene name synonym)|uniprotkb:BCL9(gene name)|psi-mi:BCL9(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483364|imex:IM-26985-127 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000357442|refseq:NP_612157.1|ensembl:ENSG00000163348(gene)|ensembl:ENST00000368457(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0007420"(brain development)|go:"GO:0030879"(mammary gland development)|go:"GO:0033599"(regulation of mammary gland epithelial cell proliferation)|go:"GO:0035034"(histone acetyltransferase regulator activity)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042393"(histone binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048589"(developmental growth)|go:"GO:0051569"(regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|mint:Q9BRQ0|rcsb pdb:2XB1|rcsb pdb:4UP0|rcsb pdb:4UP5|reactome:R-HSA-201722|reactome:R-HSA-3769402 ensembl:ENSP00000234739|ensembl:ENSG00000116128(gene)|ensembl:ENST00000234739(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0014908"(myotube differentiation involved in skeletal muscle regeneration)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR015668(B Cell Lymphoma 9)|interpro:IPR024670|mint:O00512|rcsb pdb:2GL7|rcsb pdb:2VP7|rcsb pdb:2VPB|rcsb pdb:2VPD|rcsb pdb:2VPE|rcsb pdb:2VPG|rcsb pdb:3SL9|reactome:R-HSA-201722|reactome:R-HSA-3769402|refseq:NP_004317.2|refseq:XP_005273028.1 - - comment:"author score: 56" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:pnjkTQxG5O0yk8WfuSd0MMsZ3dU9606 rogid:RCCh4ZkVE2BITRjPSL38IKnaaAk9606 rigid:E1koKbqoYSOO4FjUhIK1VX9fsso false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60671 uniprotkb:Q8WUA4 intact:EBI-721835|uniprotkb:O75572|uniprotkb:O95304|uniprotkb:Q5KSM0|uniprotkb:Q5KSM1|uniprotkb:Q9UEP1|uniprotkb:Q1W161|ensembl:ENSP00000340879|ensembl:ENSP00000371469 intact:EBI-1237062|uniprotkb:D6W557|ensembl:ENSP00000264720|ensembl:ENSP00000352536|uniprotkb:Q16632|uniprotkb:Q9BWI7 psi-mi:rad1_human(display_long)|uniprotkb:DNA repair exonuclease rad1 homolog(gene name synonym)|uniprotkb:Rad1-like DNA damage checkpoint protein(gene name synonym)|uniprotkb:RAD1(gene name)|psi-mi:RAD1(display_short)|uniprotkb:REC1(gene name synonym) psi-mi:tf3c2_human(display_long)|uniprotkb:GTF3C2(gene name)|psi-mi:GTF3C2(display_short)|uniprotkb:KIAA0011(gene name synonym)|uniprotkb:Transcription factor IIIC subunit beta(gene name synonym)|uniprotkb:TF3C-beta(gene name synonym)|uniprotkb:Transcription factor IIIC 110 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483382|imex:IM-26985-425 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002844.1|dip:DIP-46061N|ensembl:ENSG00000113456(gene)|ensembl:ENST00000341754(transcript)|ensembl:ENST00000382038(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0008853"(exodeoxyribonuclease III activity)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030896"(checkpoint clamp complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|go:"GO:0071479"(cellular response to ionizing radiation)|interpro:IPR003011(Repair protein Rad1)|interpro:IPR003021(Repair protein Rad1/Rec1)|mint:O60671|rcsb pdb:3A1J|rcsb pdb:3G65|rcsb pdb:3GGR|rcsb pdb:6J8Y|reactome:R-HSA-176187|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473 ensembl:ENSG00000115207(gene)|ensembl:ENST00000264720(transcript)|ensembl:ENST00000359541(transcript)|go:"GO:0000127"(transcription factor TFIIIC complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0042791"(5S class rRNA transcription by RNA polymerase III)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:Q8WUA4|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|refseq:NP_001030598.1|refseq:NP_001512.1|refseq:NP_001305838.1|dip:DIP-38213N - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/qtRi6bRt9RpbMSegtH/Jbw83Pg9606 rogid:D2SnUgtDMoh8axZsIMskwjmNW1c9606 rigid:4CgVGyb7VvdFFYI1dK+uwZ04ExE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60671 uniprotkb:Q8NFW8 intact:EBI-721835|uniprotkb:O75572|uniprotkb:O95304|uniprotkb:Q5KSM0|uniprotkb:Q5KSM1|uniprotkb:Q9UEP1|uniprotkb:Q1W161|ensembl:ENSP00000340879|ensembl:ENSP00000371469 intact:EBI-2816175|uniprotkb:Q9NQZ0|uniprotkb:Q96AX5|ensembl:ENSP00000229329 psi-mi:rad1_human(display_long)|uniprotkb:DNA repair exonuclease rad1 homolog(gene name synonym)|uniprotkb:Rad1-like DNA damage checkpoint protein(gene name synonym)|uniprotkb:RAD1(gene name)|psi-mi:RAD1(display_short)|uniprotkb:REC1(gene name synonym) psi-mi:neua_human(display_long)|uniprotkb:CMAS(gene name)|psi-mi:CMAS(display_short)|uniprotkb:CMP-N-acetylneuraminic acid synthase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483382|imex:IM-26985-425 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002844.1|dip:DIP-46061N|ensembl:ENSG00000113456(gene)|ensembl:ENST00000341754(transcript)|ensembl:ENST00000382038(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0008853"(exodeoxyribonuclease III activity)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030896"(checkpoint clamp complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|go:"GO:0071479"(cellular response to ionizing radiation)|interpro:IPR003011(Repair protein Rad1)|interpro:IPR003021(Repair protein Rad1/Rec1)|mint:O60671|rcsb pdb:3A1J|rcsb pdb:3G65|rcsb pdb:3GGR|rcsb pdb:6J8Y|reactome:R-HSA-176187|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473 refseq:NP_061156.1|ensembl:ENSG00000111726(gene)|ensembl:ENST00000229329(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006054"(N-acetylneuraminate metabolic process)|go:"GO:0008781"(N-acylneuraminate cytidylyltransferase activity)|go:"GO:0016020"(membrane)|interpro:IPR003329(Acylneuraminate cytidylyltransferase)|interpro:IPR023214|interpro:IPR029044|interpro:IPR036412|mint:Q8NFW8|reactome:R-HSA-4085001 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/qtRi6bRt9RpbMSegtH/Jbw83Pg9606 rogid:N8On3mF4lrgjWtwXAwzmhpUZXn49606 rigid:4CgVGyb7VvdFFYI1dK+uwZ04ExE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60671 uniprotkb:P60866 intact:EBI-721835|uniprotkb:O75572|uniprotkb:O95304|uniprotkb:Q5KSM0|uniprotkb:Q5KSM1|uniprotkb:Q9UEP1|uniprotkb:Q1W161|ensembl:ENSP00000340879|ensembl:ENSP00000371469 intact:EBI-353105|uniprotkb:P17075|uniprotkb:Q5M8S9|uniprotkb:B2R4F4|uniprotkb:B4DW28|ensembl:ENSP00000009589|ensembl:ENSP00000427788|ensembl:ENSP00000503327|ensembl:ENSP00000504123|ensembl:ENSP00000504154|ensembl:ENSP00000504670 psi-mi:rad1_human(display_long)|uniprotkb:DNA repair exonuclease rad1 homolog(gene name synonym)|uniprotkb:Rad1-like DNA damage checkpoint protein(gene name synonym)|uniprotkb:RAD1(gene name)|psi-mi:RAD1(display_short)|uniprotkb:REC1(gene name synonym) psi-mi:rs20_human(display_long)|uniprotkb:RPS20(gene name)|psi-mi:RPS20(display_short)|uniprotkb:Small ribosomal subunit protein uS10(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483382|imex:IM-26985-425 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002844.1|dip:DIP-46061N|ensembl:ENSG00000113456(gene)|ensembl:ENST00000341754(transcript)|ensembl:ENST00000382038(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0008853"(exodeoxyribonuclease III activity)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030896"(checkpoint clamp complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|go:"GO:0071479"(cellular response to ionizing radiation)|interpro:IPR003011(Repair protein Rad1)|interpro:IPR003021(Repair protein Rad1/Rec1)|mint:O60671|rcsb pdb:3A1J|rcsb pdb:3G65|rcsb pdb:3GGR|rcsb pdb:6J8Y|reactome:R-HSA-176187|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473 refseq:NP_001014.1|refseq:NP_001139699.1|dip:DIP-31245N|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|ensembl:ENSG00000008988(gene)|ensembl:ENST00000009589(transcript)|ensembl:ENST00000521262(transcript)|ensembl:ENST00000676461(transcript)|ensembl:ENST00000676918(transcript)|ensembl:ENST00000678039(transcript)|ensembl:ENST00000678683(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|interpro:IPR001848(Ribosomal protein S10)|interpro:IPR005729(Ribosomal protein S10, eukaryotic/archaeal)|interpro:IPR018268|interpro:IPR027486|interpro:IPR036838|mint:P60866|rcsb pdb:4UG0|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/qtRi6bRt9RpbMSegtH/Jbw83Pg9606 rogid:6xNxX+eP59AOm0KraCysRHUqMFw9606 rigid:4CgVGyb7VvdFFYI1dK+uwZ04ExE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60671 uniprotkb:Q9BQA1 intact:EBI-721835|uniprotkb:O75572|uniprotkb:O95304|uniprotkb:Q5KSM0|uniprotkb:Q5KSM1|uniprotkb:Q9UEP1|uniprotkb:Q1W161|ensembl:ENSP00000340879|ensembl:ENSP00000371469 intact:EBI-1237307|uniprotkb:B3KMW6|uniprotkb:Q96GK4|uniprotkb:Q9BWY3|uniprotkb:Q3LID2|uniprotkb:Q53FU2|uniprotkb:Q6JZZ5|uniprotkb:B4DP38|ensembl:ENSP00000235090 psi-mi:rad1_human(display_long)|uniprotkb:DNA repair exonuclease rad1 homolog(gene name synonym)|uniprotkb:Rad1-like DNA damage checkpoint protein(gene name synonym)|uniprotkb:RAD1(gene name)|psi-mi:RAD1(display_short)|uniprotkb:REC1(gene name synonym) psi-mi:mep50_human(display_long)|uniprotkb:WDR77(gene name)|psi-mi:WDR77(display_short)|uniprotkb:MEP50(gene name synonym)|uniprotkb:WD repeat-containing protein 77(gene name synonym)|uniprotkb:Androgen receptor cofactor p44(gene name synonym)|uniprotkb:p44/Mep50(gene name synonym)|uniprotkb:HKMT1069(orf name)|uniprotkb:Nbla10071(orf name)|uniprotkb:WD45(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483382|imex:IM-26985-425 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002844.1|dip:DIP-46061N|ensembl:ENSG00000113456(gene)|ensembl:ENST00000341754(transcript)|ensembl:ENST00000382038(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0008853"(exodeoxyribonuclease III activity)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030896"(checkpoint clamp complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|go:"GO:0071479"(cellular response to ionizing radiation)|interpro:IPR003011(Repair protein Rad1)|interpro:IPR003021(Repair protein Rad1/Rec1)|mint:O60671|rcsb pdb:3A1J|rcsb pdb:3G65|rcsb pdb:3GGR|rcsb pdb:6J8Y|reactome:R-HSA-176187|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473 refseq:NP_077007.1|refseq:NP_001303991.1|refseq:NP_001303992.1|refseq:NP_001303993.1|dip:DIP-38172N|ensembl:ENSG00000116455(gene)|ensembl:ENST00000235090(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0034709"(methylosome)|go:"GO:0045495"(pole plasm)|go:"GO:0060528"(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:"GO:0060770"(negative regulation of epithelial cell proliferation involved in prostate gland development)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:Q9BQA1|rcsb pdb:4GQB|rcsb pdb:4X60|rcsb pdb:4X61|rcsb pdb:4X63|rcsb pdb:5C9Z|rcsb pdb:5EMJ|rcsb pdb:5EMK|rcsb pdb:5EML|rcsb pdb:5EMM|rcsb pdb:5FA5|rcsb pdb:6CKC|rcsb pdb:6K1S|rcsb pdb:6RLL|rcsb pdb:6RLQ|rcsb pdb:6UGH|rcsb pdb:6UXX|rcsb pdb:6UXY|rcsb pdb:6V0N|rcsb pdb:6V0O|rcsb pdb:6V0P|rcsb pdb:7KIB|rcsb pdb:7KIC|rcsb pdb:7KID|rcsb pdb:7L1G|rcsb pdb:7M05|reactome:R-HSA-191859|reactome:R-HSA-3214858 - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/qtRi6bRt9RpbMSegtH/Jbw83Pg9606 rogid:0q4wunYtHalObC8r1wphhelIpr49606 rigid:4CgVGyb7VvdFFYI1dK+uwZ04ExE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60671 uniprotkb:O14744 intact:EBI-721835|uniprotkb:O75572|uniprotkb:O95304|uniprotkb:Q5KSM0|uniprotkb:Q5KSM1|uniprotkb:Q9UEP1|uniprotkb:Q1W161|ensembl:ENSP00000340879|ensembl:ENSP00000371469 intact:EBI-351098|uniprotkb:Q6IBR1|uniprotkb:A8MZ91|uniprotkb:Q9UKH1|uniprotkb:B5BU10|uniprotkb:D3DS33|ensembl:ENSP00000319169|uniprotkb:A8MTP3|uniprotkb:B4DX49|uniprotkb:B4DY30|uniprotkb:E2QRE7 psi-mi:rad1_human(display_long)|uniprotkb:DNA repair exonuclease rad1 homolog(gene name synonym)|uniprotkb:Rad1-like DNA damage checkpoint protein(gene name synonym)|uniprotkb:RAD1(gene name)|psi-mi:RAD1(display_short)|uniprotkb:REC1(gene name synonym) psi-mi:anm5_human(display_long)|uniprotkb:PRMT5(gene name)|psi-mi:PRMT5(display_short)|uniprotkb:IBP72(gene name synonym)|uniprotkb:JBP1(gene name synonym)|uniprotkb:HRMT1L5(gene name synonym)|uniprotkb:Shk1 kinase-binding protein 1 homolog(gene name synonym)|uniprotkb:Jak-binding protein 1(gene name synonym)|uniprotkb:72 kDa ICln-binding protein(gene name synonym)|uniprotkb:SKB1(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483382|imex:IM-26985-425 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002844.1|dip:DIP-46061N|ensembl:ENSG00000113456(gene)|ensembl:ENST00000341754(transcript)|ensembl:ENST00000382038(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0008853"(exodeoxyribonuclease III activity)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030896"(checkpoint clamp complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|go:"GO:0071479"(cellular response to ionizing radiation)|interpro:IPR003011(Repair protein Rad1)|interpro:IPR003021(Repair protein Rad1/Rec1)|mint:O60671|rcsb pdb:3A1J|rcsb pdb:3G65|rcsb pdb:3GGR|rcsb pdb:6J8Y|reactome:R-HSA-176187|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473 refseq:NP_001034708.1|refseq:NP_006100.2|refseq:NP_001269882.1|refseq:NP_001269884.1|refseq:NP_001269885.1|ensembl:ENSG00000100462(gene)|ensembl:ENST00000324366(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000785"(chromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034709"(methylosome)|go:"GO:0034969"(histone arginine methylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035243"(protein-arginine omega-N symmetric methyltransferase activity)|go:"GO:0035246"(peptidyl-arginine N-methylation)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070888"(E-box binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0097421"(liver regeneration)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR007857(Skb1 methyltransferase)|interpro:IPR025799|interpro:IPR029063|interpro:IPR035075|interpro:IPR035247|interpro:IPR035248|mint:O14744|rcsb pdb:4GQB|rcsb pdb:4X60|rcsb pdb:4X61|rcsb pdb:4X63|rcsb pdb:5C9Z|rcsb pdb:5EMJ|rcsb pdb:5EMK|rcsb pdb:5EML|rcsb pdb:5EMM|rcsb pdb:5FA5|rcsb pdb:6CKC|rcsb pdb:6K1S|rcsb pdb:6RLL|rcsb pdb:6RLQ|rcsb pdb:6UGH|rcsb pdb:6UXX|rcsb pdb:6UXY|rcsb pdb:6V0N|rcsb pdb:6V0O|rcsb pdb:6V0P|rcsb pdb:7KIB|rcsb pdb:7KIC|rcsb pdb:7KID|rcsb pdb:7L1G|rcsb pdb:7M05|reactome:R-HSA-191859|reactome:R-HSA-3214858|reactome:R-HSA-6804760|go:"GO:1904992"(positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway)|dip:DIP-33172N - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/qtRi6bRt9RpbMSegtH/Jbw83Pg9606 rogid:EwePjCDiU/fiuKOO+wnoYQ8I57I9606 rigid:4CgVGyb7VvdFFYI1dK+uwZ04ExE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60671 uniprotkb:Q14739 intact:EBI-721835|uniprotkb:O75572|uniprotkb:O95304|uniprotkb:Q5KSM0|uniprotkb:Q5KSM1|uniprotkb:Q9UEP1|uniprotkb:Q1W161|ensembl:ENSP00000340879|ensembl:ENSP00000371469 intact:EBI-1055147|uniprotkb:Q14740|uniprotkb:Q53GU7|uniprotkb:Q59FE6|uniprotkb:B2R5P3|ensembl:ENSP00000272163|ensembl:ENSP00000339883 psi-mi:rad1_human(display_long)|uniprotkb:DNA repair exonuclease rad1 homolog(gene name synonym)|uniprotkb:Rad1-like DNA damage checkpoint protein(gene name synonym)|uniprotkb:RAD1(gene name)|psi-mi:RAD1(display_short)|uniprotkb:REC1(gene name synonym) psi-mi:lbr_human(display_long)|uniprotkb:Integral nuclear envelope inner membrane protein(gene name synonym)|uniprotkb:LMN2R(gene name synonym)|uniprotkb:LBR(gene name)|psi-mi:LBR(display_short)|uniprotkb:"3-beta-hydroxysterol Delta (14)-reductase"(gene name synonym)|uniprotkb:C-14 sterol reductase(gene name synonym)|uniprotkb:Lamin-B receptor(gene name synonym)|uniprotkb:Sterol C14-reductase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483382|imex:IM-26985-425 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002844.1|dip:DIP-46061N|ensembl:ENSG00000113456(gene)|ensembl:ENST00000341754(transcript)|ensembl:ENST00000382038(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0008853"(exodeoxyribonuclease III activity)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030896"(checkpoint clamp complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|go:"GO:0071479"(cellular response to ionizing radiation)|interpro:IPR003011(Repair protein Rad1)|interpro:IPR003021(Repair protein Rad1/Rec1)|mint:O60671|rcsb pdb:3A1J|rcsb pdb:3G65|rcsb pdb:3GGR|rcsb pdb:6J8Y|reactome:R-HSA-176187|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473 refseq:NP_002287.2|refseq:NP_919424.1|refseq:XP_011542487.1|ensembl:ENSP00000272163|ensembl:ENSP00000339883|ensembl:ENSG00000143815(gene)|ensembl:ENST00000272163(transcript)|ensembl:ENST00000338179(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:2DIG|reactome:R-HSA-191273|reactome:R-HSA-2995383|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9022692|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016627"(oxidoreductase activity, acting on the CH-CH group of donors)|go:"GO:0030223"(neutrophil differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0050613"(delta14-sterol reductase activity)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0070402"(NADPH binding)|interpro:IPR001171(ERG4/ERG24 ergosterol biosynthesis protein)|interpro:IPR002999(Tudor)|interpro:IPR018083|interpro:IPR019023|mint:Q14739|dip:DIP-5987N - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/qtRi6bRt9RpbMSegtH/Jbw83Pg9606 rogid:Ns5qFZb8njsTOK90hIddW2O+uQI9606 rigid:4CgVGyb7VvdFFYI1dK+uwZ04ExE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60671 uniprotkb:Q16836 intact:EBI-721835|uniprotkb:O75572|uniprotkb:O95304|uniprotkb:Q5KSM0|uniprotkb:Q5KSM1|uniprotkb:Q9UEP1|uniprotkb:Q1W161|ensembl:ENSP00000340879|ensembl:ENSP00000371469 intact:EBI-3192352|ensembl:ENSP00000312288|uniprotkb:J3KQ17|uniprotkb:O00397|uniprotkb:O00324|uniprotkb:O00753|uniprotkb:Q4W5B4 psi-mi:rad1_human(display_long)|uniprotkb:DNA repair exonuclease rad1 homolog(gene name synonym)|uniprotkb:Rad1-like DNA damage checkpoint protein(gene name synonym)|uniprotkb:RAD1(gene name)|psi-mi:RAD1(display_short)|uniprotkb:REC1(gene name synonym) psi-mi:hcdh_human(display_long)|uniprotkb:HADH(gene name)|psi-mi:HADH(display_short)|uniprotkb:HAD(gene name synonym)|uniprotkb:HADHSC(gene name synonym)|uniprotkb:SCHAD(gene name synonym)|uniprotkb:Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase(gene name synonym)|uniprotkb:Short-chain 3-hydroxyacyl-CoA dehydrogenase(gene name synonym)|uniprotkb:HAD1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483382|imex:IM-26985-425 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002844.1|dip:DIP-46061N|ensembl:ENSG00000113456(gene)|ensembl:ENST00000341754(transcript)|ensembl:ENST00000382038(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0008853"(exodeoxyribonuclease III activity)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030896"(checkpoint clamp complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|go:"GO:0071479"(cellular response to ionizing radiation)|interpro:IPR003011(Repair protein Rad1)|interpro:IPR003021(Repair protein Rad1/Rec1)|mint:O60671|rcsb pdb:3A1J|rcsb pdb:3G65|rcsb pdb:3GGR|rcsb pdb:6J8Y|reactome:R-HSA-176187|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473 interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR022694|interpro:IPR036291|mint:Q16836|rcsb pdb:1F0Y|rcsb pdb:1F12|rcsb pdb:1F14|rcsb pdb:1F17|rcsb pdb:1IL0|rcsb pdb:1LSJ|rcsb pdb:1LSO|rcsb pdb:1M75|rcsb pdb:1M76|rcsb pdb:2HDH|rcsb pdb:3HAD|rcsb pdb:3RQS|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|ensembl:ENSG00000138796(gene)|ensembl:ENST00000309522(transcript)|reactome:R-HSA-77350|reactome:R-HSA-77352|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0014823"(response to activity)|go:"GO:0016740"(transferase activity)|go:"GO:0032868"(response to insulin)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0046676"(negative regulation of insulin secretion)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0070403"(NAD+ binding)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|interpro:IPR006108(3-hydroxyacyl-CoA dehydrogenase, C-terminal)|interpro:IPR006176(3-hydroxyacyl-CoA dehydrogenase, NAD binding)|interpro:IPR006180(3-hydroxyacyl-CoA dehydrogenase, conserved site)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|refseq:NP_001171634.2|refseq:NP_005318.3 - - comment:"author score: 29" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/qtRi6bRt9RpbMSegtH/Jbw83Pg9606 rogid:Al8M+JdB4H+QnwITh8KcicdI2x49606 rigid:4CgVGyb7VvdFFYI1dK+uwZ04ExE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60671 uniprotkb:Q9UKN8 intact:EBI-721835|uniprotkb:O75572|uniprotkb:O95304|uniprotkb:Q5KSM0|uniprotkb:Q5KSM1|uniprotkb:Q9UEP1|uniprotkb:Q1W161|ensembl:ENSP00000340879|ensembl:ENSP00000371469 intact:EBI-1237240|uniprotkb:Q5VZJ7|ensembl:ENSP00000361219 psi-mi:rad1_human(display_long)|uniprotkb:DNA repair exonuclease rad1 homolog(gene name synonym)|uniprotkb:Rad1-like DNA damage checkpoint protein(gene name synonym)|uniprotkb:RAD1(gene name)|psi-mi:RAD1(display_short)|uniprotkb:REC1(gene name synonym) psi-mi:tf3c4_human(display_long)|uniprotkb:GTF3C4(gene name)|psi-mi:GTF3C4(display_short)|uniprotkb:Transcription factor IIIC subunit delta(gene name synonym)|uniprotkb:TF3C-delta(gene name synonym)|uniprotkb:Transcription factor IIIC 90 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483382|imex:IM-26985-425 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002844.1|dip:DIP-46061N|ensembl:ENSG00000113456(gene)|ensembl:ENST00000341754(transcript)|ensembl:ENST00000382038(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0008853"(exodeoxyribonuclease III activity)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030896"(checkpoint clamp complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|go:"GO:0071479"(cellular response to ionizing radiation)|interpro:IPR003011(Repair protein Rad1)|interpro:IPR003021(Repair protein Rad1/Rec1)|mint:O60671|rcsb pdb:3A1J|rcsb pdb:3G65|rcsb pdb:3GGR|rcsb pdb:6J8Y|reactome:R-HSA-176187|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473 refseq:NP_036336.2|ensembl:ENSG00000125484(gene)|ensembl:ENST00000372146(transcript)|go:"GO:0000127"(transcription factor TFIIIC complex)|go:"GO:0003677"(DNA binding)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0006384"(transcription initiation from RNA polymerase III promoter)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0042791"(5S class rRNA transcription by RNA polymerase III)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR024761|interpro:IPR024764|interpro:IPR036322|interpro:IPR044230|mint:Q9UKN8|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066 - - comment:"author score: 34" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/qtRi6bRt9RpbMSegtH/Jbw83Pg9606 rogid:OFldz80WMs7KQ59Of0rkkj80lyc9606 rigid:4CgVGyb7VvdFFYI1dK+uwZ04ExE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60671 uniprotkb:Q9Y6H1 intact:EBI-721835|uniprotkb:O75572|uniprotkb:O95304|uniprotkb:Q5KSM0|uniprotkb:Q5KSM1|uniprotkb:Q9UEP1|uniprotkb:Q1W161|ensembl:ENSP00000340879|ensembl:ENSP00000371469 intact:EBI-2321769|uniprotkb:Q498C3|uniprotkb:Q6NZ50|ensembl:ENSP00000378812 psi-mi:rad1_human(display_long)|uniprotkb:DNA repair exonuclease rad1 homolog(gene name synonym)|uniprotkb:Rad1-like DNA damage checkpoint protein(gene name synonym)|uniprotkb:RAD1(gene name)|psi-mi:RAD1(display_short)|uniprotkb:REC1(gene name synonym) psi-mi:chch2_human(display_long)|uniprotkb:CHCHD2(gene name)|psi-mi:CHCHD2(display_short)|uniprotkb:C7orf17(gene name synonym)|uniprotkb:HCV NS2 trans-regulated protein(gene name synonym)|uniprotkb:Aging-associated gene 10 protein(gene name synonym)|uniprotkb:AAG10(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483382|imex:IM-26985-425 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002844.1|dip:DIP-46061N|ensembl:ENSG00000113456(gene)|ensembl:ENST00000341754(transcript)|ensembl:ENST00000382038(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0008853"(exodeoxyribonuclease III activity)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030896"(checkpoint clamp complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|go:"GO:0071479"(cellular response to ionizing radiation)|interpro:IPR003011(Repair protein Rad1)|interpro:IPR003021(Repair protein Rad1/Rec1)|mint:O60671|rcsb pdb:3A1J|rcsb pdb:3G65|rcsb pdb:3GGR|rcsb pdb:6J8Y|reactome:R-HSA-176187|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473 refseq:NP_057223.1|ensembl:ENSG00000106153(gene)|ensembl:ENST00000395422(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900037"(regulation of cellular response to hypoxia)|go:"GO:1905448"(positive regulation of mitochondrial ATP synthesis coupled electron transport)|interpro:IPR010625(CHCH)|mint:Q9Y6H1|reactome:R-HSA-1268020 - - comment:"author score: 51" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/qtRi6bRt9RpbMSegtH/Jbw83Pg9606 rogid:fdx3lE51+yZ1k3uwh8/LDKJC+CQ9606 rigid:4CgVGyb7VvdFFYI1dK+uwZ04ExE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O60671 uniprotkb:P68363 intact:EBI-721835|uniprotkb:O75572|uniprotkb:O95304|uniprotkb:Q5KSM0|uniprotkb:Q5KSM1|uniprotkb:Q9UEP1|uniprotkb:Q1W161|ensembl:ENSP00000340879|ensembl:ENSP00000371469 intact:EBI-487083|intact:EBI-1384226|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:Q27I68|ensembl:ENSP00000336799|uniprotkb:Q8WU19 psi-mi:rad1_human(display_long)|uniprotkb:DNA repair exonuclease rad1 homolog(gene name synonym)|uniprotkb:Rad1-like DNA damage checkpoint protein(gene name synonym)|uniprotkb:RAD1(gene name)|psi-mi:RAD1(display_short)|uniprotkb:REC1(gene name synonym) psi-mi:tba1b_human(display_long)|uniprotkb:TUBA1B(gene name)|psi-mi:TUBA1B(display_short)|uniprotkb:Tubulin alpha-ubiquitous chain(gene name synonym)|uniprotkb:Alpha-tubulin ubiquitous(gene name synonym)|uniprotkb:Tubulin K-alpha-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483382|imex:IM-26985-425 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002844.1|dip:DIP-46061N|ensembl:ENSG00000113456(gene)|ensembl:ENST00000341754(transcript)|ensembl:ENST00000382038(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0008853"(exodeoxyribonuclease III activity)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030896"(checkpoint clamp complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051598"(meiotic recombination checkpoint signaling)|go:"GO:0071479"(cellular response to ionizing radiation)|interpro:IPR003011(Repair protein Rad1)|interpro:IPR003021(Repair protein Rad1/Rec1)|mint:O60671|rcsb pdb:3A1J|rcsb pdb:3G65|rcsb pdb:3GGR|rcsb pdb:6J8Y|reactome:R-HSA-176187|reactome:R-HSA-5685938|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473 refseq:NP_006073.2|ensembl:ENSG00000123416(gene)|ensembl:ENST00000336023(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-983189|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|go:"GO:0045121"(membrane raft)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68363|rcsb pdb:2E4H|rcsb pdb:5IJ0|rcsb pdb:5IJ9|rcsb pdb:5N5N|rcsb pdb:6E7B|rcsb pdb:6E7C|rcsb pdb:6I2I|go:"GO:0051301"(cell division)|rcsb pdb:6J4V|rcsb pdb:6J8O|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|rcsb pdb:6S8L|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9013407|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-2132295|reactome:R-HSA-9668328 - - comment:"author score: 54" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/qtRi6bRt9RpbMSegtH/Jbw83Pg9606 rogid:D4YpuLCXl/S+53qV7P7sF81aARY9606 rigid:4CgVGyb7VvdFFYI1dK+uwZ04ExE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0CAP2 uniprotkb:Q9BWH6 intact:EBI-9657655|uniprotkb:Q96NF5|uniprotkb:Q6EFN8|uniprotkb:Q6EEV3|uniprotkb:Q9Y3V6|uniprotkb:Q8NC58|uniprotkb:Q96DI5|uniprotkb:Q6EF02|uniprotkb:Q6K050|uniprotkb:Q6K046|uniprotkb:Q6K051|uniprotkb:Q6EF01|uniprotkb:Q6EES2|uniprotkb:Q8NCF3|uniprotkb:Q6EM48|uniprotkb:Q6EF46|uniprotkb:Q6ZQZ3|uniprotkb:Q6EER8|uniprotkb:Q96JB7|uniprotkb:Q6EF00|ensembl:ENSP00000299638 intact:EBI-1048085|uniprotkb:Q9H9I2|uniprotkb:Q9NSQ5|uniprotkb:Q9P2E4|uniprotkb:Q9UFS7|ensembl:ENSP00000306123 psi-mi:grl1a_human(display_long)|uniprotkb:POLR2M(gene name)|psi-mi:POLR2M(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit M(gene name synonym)|uniprotkb:GRINL1A(gene name synonym)|uniprotkb:Glutamate receptor-like protein 1A(gene name synonym) psi-mi:rpap1_human(display_long)|uniprotkb:RPAP1(gene name)|psi-mi:RPAP1(display_short)|uniprotkb:KIAA1403(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482919|imex:IM-26985-423 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001018112.1|refseq:NP_056347.1|dip:DIP-61933N|ensembl:ENSG00000255529(gene)|ensembl:ENST00000299638(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051685"(maintenance of ER location)|interpro:IPR026213|mint:P0CAP2|rcsb pdb:6DRD refseq:NP_056355.2|refseq:XP_005254354.1|ensembl:ENSG00000103932(gene)|ensembl:ENST00000304330(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006366"(transcription by RNA polymerase II)|interpro:IPR013929(RNA polymerase II-associated protein 1, C-terminal)|interpro:IPR013930(RNA polymerase II-associated protein 1, N-terminal)|interpro:IPR039913|mint:Q9BWH6 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:G0QVxeD0uvJTl0VPn+b3pV6zLe89606 rogid:9vO/6r2beuU+WAmMIaz9ZVNLGQI9606 rigid:/44uHYNdWEgFUftM68YkL14pVXg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0CAP2 uniprotkb:P22528 intact:EBI-9657655|uniprotkb:Q96NF5|uniprotkb:Q6EFN8|uniprotkb:Q6EEV3|uniprotkb:Q9Y3V6|uniprotkb:Q8NC58|uniprotkb:Q96DI5|uniprotkb:Q6EF02|uniprotkb:Q6K050|uniprotkb:Q6K046|uniprotkb:Q6K051|uniprotkb:Q6EF01|uniprotkb:Q6EES2|uniprotkb:Q8NCF3|uniprotkb:Q6EM48|uniprotkb:Q6EF46|uniprotkb:Q6ZQZ3|uniprotkb:Q6EER8|uniprotkb:Q96JB7|uniprotkb:Q6EF00|ensembl:ENSP00000299638 intact:EBI-1058892|ensembl:ENSP00000306461|uniprotkb:B2R5H7|uniprotkb:P22529|uniprotkb:P22530|uniprotkb:Q5T524 psi-mi:grl1a_human(display_long)|uniprotkb:POLR2M(gene name)|psi-mi:POLR2M(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit M(gene name synonym)|uniprotkb:GRINL1A(gene name synonym)|uniprotkb:Glutamate receptor-like protein 1A(gene name synonym) psi-mi:spr1b_human(display_long)|uniprotkb:SPRR1B(gene name)|psi-mi:SPRR1B(display_short)|uniprotkb:Small proline-rich protein IB(gene name synonym)|uniprotkb:14.9 kDa pancornulin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482919|imex:IM-26985-423 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001018112.1|refseq:NP_056347.1|dip:DIP-61933N|ensembl:ENSG00000255529(gene)|ensembl:ENST00000299638(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051685"(maintenance of ER location)|interpro:IPR026213|mint:P0CAP2|rcsb pdb:6DRD ensembl:ENSG00000169469(gene)|ensembl:ENST00000307098(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0031424"(keratinization)|interpro:IPR003302("Cornifin (SPRR)")|mint:P22528|reactome:R-HSA-6809371|refseq:NP_003116.2 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:G0QVxeD0uvJTl0VPn+b3pV6zLe89606 rogid:WU0vu+DHdIJm0x40HdcpAdJgdgo9606 rigid:/44uHYNdWEgFUftM68YkL14pVXg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0CAP2 uniprotkb:Q9UHW5 intact:EBI-9657655|uniprotkb:Q96NF5|uniprotkb:Q6EFN8|uniprotkb:Q6EEV3|uniprotkb:Q9Y3V6|uniprotkb:Q8NC58|uniprotkb:Q96DI5|uniprotkb:Q6EF02|uniprotkb:Q6K050|uniprotkb:Q6K046|uniprotkb:Q6K051|uniprotkb:Q6EF01|uniprotkb:Q6EES2|uniprotkb:Q8NCF3|uniprotkb:Q6EM48|uniprotkb:Q6EF46|uniprotkb:Q6ZQZ3|uniprotkb:Q6EER8|uniprotkb:Q96JB7|uniprotkb:Q6EF00|ensembl:ENSP00000299638 intact:EBI-395491|uniprotkb:Q53FS3|uniprotkb:Q6UVZ6|uniprotkb:Q7Z3D3|uniprotkb:Q8NEI2|uniprotkb:Q96HK9|uniprotkb:B2RC54|uniprotkb:D4YWV1|ensembl:ENSP00000228827|uniprotkb:F5H759 psi-mi:grl1a_human(display_long)|uniprotkb:POLR2M(gene name)|psi-mi:POLR2M(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit M(gene name synonym)|uniprotkb:GRINL1A(gene name synonym)|uniprotkb:Glutamate receptor-like protein 1A(gene name synonym) psi-mi:gpn3_human(display_long)|uniprotkb:ATPBD1C(gene name synonym)|uniprotkb:ATP-binding domain 1 family member C(gene name synonym)|uniprotkb:GPN3(gene name)|psi-mi:GPN3(display_short)|uniprotkb:AD-009(orf name)|uniprotkb:UNQ1876/PRO4319(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482919|imex:IM-26985-423 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001018112.1|refseq:NP_056347.1|dip:DIP-61933N|ensembl:ENSG00000255529(gene)|ensembl:ENST00000299638(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051685"(maintenance of ER location)|interpro:IPR026213|mint:P0CAP2|rcsb pdb:6DRD refseq:NP_001157844.1|refseq:NP_001157845.1|refseq:NP_057385.3|ensembl:ENSG00000111231(gene)|ensembl:ENST00000228827(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0032991"(protein-containing complex)|interpro:IPR004130(Protein of unknown function, ATP binding)|interpro:IPR027417|interpro:IPR030228|mint:Q9UHW5 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:G0QVxeD0uvJTl0VPn+b3pV6zLe89606 rogid:fKBsnLcvitaM76zQUW+MQXDPxTA9606 rigid:/44uHYNdWEgFUftM68YkL14pVXg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0CAP2 uniprotkb:O75586 intact:EBI-9657655|uniprotkb:Q96NF5|uniprotkb:Q6EFN8|uniprotkb:Q6EEV3|uniprotkb:Q9Y3V6|uniprotkb:Q8NC58|uniprotkb:Q96DI5|uniprotkb:Q6EF02|uniprotkb:Q6K050|uniprotkb:Q6K046|uniprotkb:Q6K051|uniprotkb:Q6EF01|uniprotkb:Q6EES2|uniprotkb:Q8NCF3|uniprotkb:Q6EM48|uniprotkb:Q6EF46|uniprotkb:Q6ZQZ3|uniprotkb:Q6EER8|uniprotkb:Q96JB7|uniprotkb:Q6EF00|ensembl:ENSP00000299638 intact:EBI-394624|uniprotkb:Q6FHQ4|uniprotkb:Q9BTH1|uniprotkb:Q9UHL1|uniprotkb:O15401|uniprotkb:Q53FE3|uniprotkb:Q53HJ3|uniprotkb:B4DU17|uniprotkb:B4E2P0|ensembl:ENSP00000256379 psi-mi:grl1a_human(display_long)|uniprotkb:POLR2M(gene name)|psi-mi:POLR2M(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit M(gene name synonym)|uniprotkb:GRINL1A(gene name synonym)|uniprotkb:Glutamate receptor-like protein 1A(gene name synonym) psi-mi:med6_human(display_long)|uniprotkb:ARC33(gene name synonym)|uniprotkb:MED6(gene name)|psi-mi:MED6(display_short)|uniprotkb:Mediator complex subunit 6(gene name synonym)|uniprotkb:Activator-recruited cofactor 33 kDa component(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-28(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482919|imex:IM-26985-423 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001018112.1|refseq:NP_056347.1|dip:DIP-61933N|ensembl:ENSG00000255529(gene)|ensembl:ENST00000299638(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051685"(maintenance of ER location)|interpro:IPR026213|mint:P0CAP2|rcsb pdb:6DRD refseq:NP_005457.2|refseq:NP_001271138.1|refseq:NP_001271139.1|refseq:NP_001271140.1|ensembl:ENSG00000133997(gene)|ensembl:ENST00000256379(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070847"(core mediator complex)|interpro:IPR007018(MED6 mediator)|interpro:IPR016820(Mediator complex, subunit 6, metazoa/plant)|interpro:IPR038566|mint:O75586|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31456N - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:G0QVxeD0uvJTl0VPn+b3pV6zLe89606 rogid:QYK+2tX/HC1OGGPu3b3S1v/ODR89606 rigid:/44uHYNdWEgFUftM68YkL14pVXg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0CAP2 uniprotkb:Q9H7N4 intact:EBI-9657655|uniprotkb:Q96NF5|uniprotkb:Q6EFN8|uniprotkb:Q6EEV3|uniprotkb:Q9Y3V6|uniprotkb:Q8NC58|uniprotkb:Q96DI5|uniprotkb:Q6EF02|uniprotkb:Q6K050|uniprotkb:Q6K046|uniprotkb:Q6K051|uniprotkb:Q6EF01|uniprotkb:Q6EES2|uniprotkb:Q8NCF3|uniprotkb:Q6EM48|uniprotkb:Q6EF46|uniprotkb:Q6ZQZ3|uniprotkb:Q6EER8|uniprotkb:Q96JB7|uniprotkb:Q6EF00|ensembl:ENSP00000299638 intact:EBI-1222181|uniprotkb:Q7Z5V7|uniprotkb:Q8WVA1|uniprotkb:Q9NR59|ensembl:ENSP00000353769 psi-mi:grl1a_human(display_long)|uniprotkb:POLR2M(gene name)|psi-mi:POLR2M(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit M(gene name synonym)|uniprotkb:GRINL1A(gene name synonym)|uniprotkb:Glutamate receptor-like protein 1A(gene name synonym) psi-mi:sfr19_human(display_long)|uniprotkb:SCAF1(gene name)|psi-mi:SCAF1(display_short)|uniprotkb:SRA1(gene name synonym)|uniprotkb:SFRS19(gene name synonym)|uniprotkb:Serine arginine-rich pre-mRNA splicing factor SR-A1(gene name synonym)|uniprotkb:SR-related-CTD-associated factor(gene name synonym)|uniprotkb:SR-related C-terminal domain-associated factor 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482919|imex:IM-26985-423 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001018112.1|refseq:NP_056347.1|dip:DIP-61933N|ensembl:ENSG00000255529(gene)|ensembl:ENST00000299638(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051685"(maintenance of ER location)|interpro:IPR026213|mint:P0CAP2|rcsb pdb:6DRD refseq:NP_067051.2|refseq:XP_005259179.1|ensembl:ENSG00000126461(gene)|ensembl:ENST00000360565(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|interpro:IPR042841|mint:Q9H7N4 - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:G0QVxeD0uvJTl0VPn+b3pV6zLe89606 rogid:pF10w7xZFQgiVOiZ/mmPKKArwHE9606 rigid:/44uHYNdWEgFUftM68YkL14pVXg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0CAP2 uniprotkb:Q9HCN4 intact:EBI-9657655|uniprotkb:Q96NF5|uniprotkb:Q6EFN8|uniprotkb:Q6EEV3|uniprotkb:Q9Y3V6|uniprotkb:Q8NC58|uniprotkb:Q96DI5|uniprotkb:Q6EF02|uniprotkb:Q6K050|uniprotkb:Q6K046|uniprotkb:Q6K051|uniprotkb:Q6EF01|uniprotkb:Q6EES2|uniprotkb:Q8NCF3|uniprotkb:Q6EM48|uniprotkb:Q6EF46|uniprotkb:Q6ZQZ3|uniprotkb:Q6EER8|uniprotkb:Q96JB7|uniprotkb:Q6EF00|ensembl:ENSP00000299638 intact:EBI-745137|uniprotkb:O76004|uniprotkb:B4DQJ5|uniprotkb:B4DXU4|uniprotkb:B4DQM4|ensembl:ENSP00000476446|uniprotkb:B5MBZ5 psi-mi:grl1a_human(display_long)|uniprotkb:POLR2M(gene name)|psi-mi:POLR2M(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit M(gene name synonym)|uniprotkb:GRINL1A(gene name synonym)|uniprotkb:Glutamate receptor-like protein 1A(gene name synonym) psi-mi:gpn1_human(display_long)|uniprotkb:XAB1(gene name synonym)|uniprotkb:XPA-binding protein 1(gene name synonym)|uniprotkb:MBD2-interacting protein(gene name synonym)|uniprotkb:GPN1(gene name)|psi-mi:GPN1(display_short)|uniprotkb:MBDIN(gene name synonym)|uniprotkb:HUSSY-23(orf name)|uniprotkb:RNAPII-associated protein 4(gene name synonym)|uniprotkb:RPAP4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482919|imex:IM-26985-423 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001018112.1|refseq:NP_056347.1|dip:DIP-61933N|ensembl:ENSG00000255529(gene)|ensembl:ENST00000299638(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051685"(maintenance of ER location)|interpro:IPR026213|mint:P0CAP2|rcsb pdb:6DRD refseq:NP_001138519.1|refseq:NP_001138520.1|refseq:NP_001138521.1|refseq:NP_009197.2|ensembl:ENSG00000198522(gene)|ensembl:ENST00000610189(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004130(Protein of unknown function, ATP binding)|interpro:IPR027417|interpro:IPR030230|mint:Q9HCN4 - - comment:"author score: 28" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:G0QVxeD0uvJTl0VPn+b3pV6zLe89606 rogid:QZOTFh9d1hOcoG1DxAueYEwbOpc9606 rigid:/44uHYNdWEgFUftM68YkL14pVXg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0CAP2 uniprotkb:O95104 intact:EBI-9657655|uniprotkb:Q96NF5|uniprotkb:Q6EFN8|uniprotkb:Q6EEV3|uniprotkb:Q9Y3V6|uniprotkb:Q8NC58|uniprotkb:Q96DI5|uniprotkb:Q6EF02|uniprotkb:Q6K050|uniprotkb:Q6K046|uniprotkb:Q6K051|uniprotkb:Q6EF01|uniprotkb:Q6EES2|uniprotkb:Q8NCF3|uniprotkb:Q6EM48|uniprotkb:Q6EF46|uniprotkb:Q6ZQZ3|uniprotkb:Q6EER8|uniprotkb:Q96JB7|uniprotkb:Q6EF00|ensembl:ENSP00000299638 intact:EBI-2854897|uniprotkb:Q6P1M5|uniprotkb:Q8N3I8|uniprotkb:Q9ULP8|uniprotkb:Q0P5W8|uniprotkb:Q9UFM1|uniprotkb:C9JLZ0|ensembl:ENSP00000286835 psi-mi:grl1a_human(display_long)|uniprotkb:POLR2M(gene name)|psi-mi:POLR2M(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit M(gene name synonym)|uniprotkb:GRINL1A(gene name synonym)|uniprotkb:Glutamate receptor-like protein 1A(gene name synonym) psi-mi:scaf4_human(display_long)|uniprotkb:SCAF4(gene name)|psi-mi:SCAF4(display_short)|uniprotkb:Splicing factor, arginine/serine-rich 15(gene name synonym)|uniprotkb:SFRS15(gene name synonym)|uniprotkb:KIAA1172(gene name synonym)|uniprotkb:CTD-binding SR-like protein RA4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482919|imex:IM-26985-423 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001018112.1|refseq:NP_056347.1|dip:DIP-61933N|ensembl:ENSG00000255529(gene)|ensembl:ENST00000299638(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051685"(maintenance of ER location)|interpro:IPR026213|mint:P0CAP2|rcsb pdb:6DRD refseq:NP_001138916.1|refseq:NP_001138917.1|refseq:NP_065757.1|ensembl:ENSG00000156304(gene)|ensembl:ENST00000286835(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|go:"GO:2000805"("negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled")|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034369|interpro:IPR035979|mint:O95104|rcsb pdb:6XKB - - comment:"author score: 30" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:G0QVxeD0uvJTl0VPn+b3pV6zLe89606 rogid:l++VfjjY/kfVHl+bhXTWsyyL4Zc9606 rigid:/44uHYNdWEgFUftM68YkL14pVXg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0CAP2 uniprotkb:O60942 intact:EBI-9657655|uniprotkb:Q96NF5|uniprotkb:Q6EFN8|uniprotkb:Q6EEV3|uniprotkb:Q9Y3V6|uniprotkb:Q8NC58|uniprotkb:Q96DI5|uniprotkb:Q6EF02|uniprotkb:Q6K050|uniprotkb:Q6K046|uniprotkb:Q6K051|uniprotkb:Q6EF01|uniprotkb:Q6EES2|uniprotkb:Q8NCF3|uniprotkb:Q6EM48|uniprotkb:Q6EF46|uniprotkb:Q6ZQZ3|uniprotkb:Q6EER8|uniprotkb:Q96JB7|uniprotkb:Q6EF00|ensembl:ENSP00000299638 intact:EBI-1237132|uniprotkb:O43483|uniprotkb:O60257|uniprotkb:O60351|uniprotkb:Q5TCW8|uniprotkb:Q8WUM8|uniprotkb:E1P513|uniprotkb:E1P514|ensembl:ENSP00000358497 psi-mi:grl1a_human(display_long)|uniprotkb:POLR2M(gene name)|psi-mi:POLR2M(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit M(gene name synonym)|uniprotkb:GRINL1A(gene name synonym)|uniprotkb:Glutamate receptor-like protein 1A(gene name synonym) psi-mi:mce1_human(display_long)|uniprotkb:RNGTT(gene name)|psi-mi:RNGTT(display_short)|uniprotkb:CAP1A(gene name synonym)|uniprotkb:HCE(gene name synonym)|uniprotkb:HCAP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482919|imex:IM-26985-423 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001018112.1|refseq:NP_056347.1|dip:DIP-61933N|ensembl:ENSG00000255529(gene)|ensembl:ENST00000299638(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051685"(maintenance of ER location)|interpro:IPR026213|mint:P0CAP2|rcsb pdb:6DRD refseq:NP_001273355.1|refseq:NP_001273357.1|refseq:NP_003791.3|dip:DIP-61014N|ensembl:ENSG00000111880(gene)|ensembl:ENST00000369485(transcript)|go:"GO:0004484"(mRNA guanylyltransferase activity)|go:"GO:0004651"(polynucleotide 5'-phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0006396"(RNA processing)|go:"GO:0008192"(RNA guanylyltransferase activity)|go:"GO:0050355"(triphosphatase activity)|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR001339(mRNA capping enzyme)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013846(mRNA capping enzyme, C-terminal)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR017074(mRNA capping enzyme, bifunctional)|interpro:IPR020422|interpro:IPR029021|mint:O60942|rcsb pdb:2C46|rcsb pdb:3S24|reactome:R-HSA-167160|reactome:R-HSA-72086|reactome:R-HSA-77075 - - comment:"author score: 30" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:G0QVxeD0uvJTl0VPn+b3pV6zLe89606 rogid:xiqdXQd75dIqosHNWDCIs1ORyJQ9606 rigid:/44uHYNdWEgFUftM68YkL14pVXg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0CAP2 uniprotkb:A0JLT2 intact:EBI-9657655|uniprotkb:Q96NF5|uniprotkb:Q6EFN8|uniprotkb:Q6EEV3|uniprotkb:Q9Y3V6|uniprotkb:Q8NC58|uniprotkb:Q96DI5|uniprotkb:Q6EF02|uniprotkb:Q6K050|uniprotkb:Q6K046|uniprotkb:Q6K051|uniprotkb:Q6EF01|uniprotkb:Q6EES2|uniprotkb:Q8NCF3|uniprotkb:Q6EM48|uniprotkb:Q6EF46|uniprotkb:Q6ZQZ3|uniprotkb:Q6EER8|uniprotkb:Q96JB7|uniprotkb:Q6EF00|ensembl:ENSP00000299638 intact:EBI-394430|uniprotkb:Q8IV02|intact:EBI-394763|uniprotkb:Q8IZD1 psi-mi:grl1a_human(display_long)|uniprotkb:POLR2M(gene name)|psi-mi:POLR2M(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit M(gene name synonym)|uniprotkb:GRINL1A(gene name synonym)|uniprotkb:Glutamate receptor-like protein 1A(gene name synonym) psi-mi:med19_human(display_long)|uniprotkb:MED19(gene name)|psi-mi:MED19(display_short)|uniprotkb:LCMR1(gene name synonym)|uniprotkb:Lung cancer metastasis-related protein 1(gene name synonym)|uniprotkb:Mediator complex subunit 19(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482919|imex:IM-26985-423 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001018112.1|refseq:NP_056347.1|dip:DIP-61933N|ensembl:ENSG00000255529(gene)|ensembl:ENST00000299638(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051685"(maintenance of ER location)|interpro:IPR026213|mint:P0CAP2|rcsb pdb:6DRD refseq:NP_001304007.1|refseq:NP_703151.2|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR019403|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|mint:A0JLT2|dip:DIP-31467N - - comment:"author score: 32" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:G0QVxeD0uvJTl0VPn+b3pV6zLe89606 rogid:zcHhU2hQvuTpkFZz/xEKYmjrwOA9606 rigid:/44uHYNdWEgFUftM68YkL14pVXg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0CAP2 uniprotkb:O60244 intact:EBI-9657655|uniprotkb:Q96NF5|uniprotkb:Q6EFN8|uniprotkb:Q6EEV3|uniprotkb:Q9Y3V6|uniprotkb:Q8NC58|uniprotkb:Q96DI5|uniprotkb:Q6EF02|uniprotkb:Q6K050|uniprotkb:Q6K046|uniprotkb:Q6K051|uniprotkb:Q6EF01|uniprotkb:Q6EES2|uniprotkb:Q8NCF3|uniprotkb:Q6EM48|uniprotkb:Q6EF46|uniprotkb:Q6ZQZ3|uniprotkb:Q6EER8|uniprotkb:Q96JB7|uniprotkb:Q6EF00|ensembl:ENSP00000299638 intact:EBI-394489|uniprotkb:Q4KMR7|uniprotkb:Q9UNB3|ensembl:ENSP00000323720 psi-mi:grl1a_human(display_long)|uniprotkb:POLR2M(gene name)|psi-mi:POLR2M(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit M(gene name synonym)|uniprotkb:GRINL1A(gene name synonym)|uniprotkb:Glutamate receptor-like protein 1A(gene name synonym) psi-mi:med14_human(display_long)|uniprotkb:TRAP170(gene name synonym)|uniprotkb:MED14(gene name)|psi-mi:MED14(display_short)|uniprotkb:ARC150(gene name synonym)|uniprotkb:DRIP150(gene name synonym)|uniprotkb:EXLM1(gene name synonym)|uniprotkb:RGR1(gene name synonym)|uniprotkb:Mediator complex subunit 14(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 2(gene name synonym)|uniprotkb:RGR1 homolog(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP150(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 150 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 170 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 150 kDa component(gene name synonym)|uniprotkb:CRSP2(gene name synonym)|uniprotkb:CXorf4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482919|imex:IM-26985-423 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001018112.1|refseq:NP_056347.1|dip:DIP-61933N|ensembl:ENSG00000255529(gene)|ensembl:ENST00000299638(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051685"(maintenance of ER location)|interpro:IPR026213|mint:P0CAP2|rcsb pdb:6DRD refseq:NP_004220.2|ensembl:ENSG00000180182(gene)|ensembl:ENST00000324817(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR013947(Mediator complex, subunit MED14)|mint:O60244|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31460N - - comment:"author score: 34" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:G0QVxeD0uvJTl0VPn+b3pV6zLe89606 rogid:73RBAnwmB4Lyl/kcsg7NKSUmA4c9606 rigid:/44uHYNdWEgFUftM68YkL14pVXg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0CAP2 uniprotkb:Q96G25 intact:EBI-9657655|uniprotkb:Q96NF5|uniprotkb:Q6EFN8|uniprotkb:Q6EEV3|uniprotkb:Q9Y3V6|uniprotkb:Q8NC58|uniprotkb:Q96DI5|uniprotkb:Q6EF02|uniprotkb:Q6K050|uniprotkb:Q6K046|uniprotkb:Q6K051|uniprotkb:Q6EF01|uniprotkb:Q6EES2|uniprotkb:Q8NCF3|uniprotkb:Q6EM48|uniprotkb:Q6EF46|uniprotkb:Q6ZQZ3|uniprotkb:Q6EER8|uniprotkb:Q96JB7|uniprotkb:Q6EF00|ensembl:ENSP00000299638 intact:EBI-394405|uniprotkb:A9IZ91|uniprotkb:Q96FQ4|uniprotkb:A9IZ92|uniprotkb:Q5JUY8|ensembl:ENSP00000361535 psi-mi:grl1a_human(display_long)|uniprotkb:POLR2M(gene name)|psi-mi:POLR2M(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit M(gene name synonym)|uniprotkb:GRINL1A(gene name synonym)|uniprotkb:Glutamate receptor-like protein 1A(gene name synonym) psi-mi:med8_human(display_long)|uniprotkb:MED8(gene name)|psi-mi:MED8(display_short)|uniprotkb:Mediator complex subunit 8(gene name synonym)|uniprotkb:Activator-recruited cofactor 32 kDa component(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482919|imex:IM-26985-423 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001018112.1|refseq:NP_056347.1|dip:DIP-61933N|ensembl:ENSG00000255529(gene)|ensembl:ENST00000299638(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051685"(maintenance of ER location)|interpro:IPR026213|mint:P0CAP2|rcsb pdb:6DRD refseq:NP_443109.2|refseq:NP_963836.2|refseq:NP_001001653.1|ensembl:ENSG00000159479(gene)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR019364|mint:Q96G25|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENST00000372457(transcript) - - comment:"author score: 35" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:G0QVxeD0uvJTl0VPn+b3pV6zLe89606 rogid:e/ye7rfa2E1XOPb5vVhI9Nvqmxw9606 rigid:/44uHYNdWEgFUftM68YkL14pVXg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0CAP2 uniprotkb:Q6P2C8 intact:EBI-9657655|uniprotkb:Q96NF5|uniprotkb:Q6EFN8|uniprotkb:Q6EEV3|uniprotkb:Q9Y3V6|uniprotkb:Q8NC58|uniprotkb:Q96DI5|uniprotkb:Q6EF02|uniprotkb:Q6K050|uniprotkb:Q6K046|uniprotkb:Q6K051|uniprotkb:Q6EF01|uniprotkb:Q6EES2|uniprotkb:Q8NCF3|uniprotkb:Q6EM48|uniprotkb:Q6EF46|uniprotkb:Q6ZQZ3|uniprotkb:Q6EER8|uniprotkb:Q96JB7|uniprotkb:Q6EF00|ensembl:ENSP00000299638 intact:EBI-394603|uniprotkb:Q4F964|uniprotkb:O95401|uniprotkb:Q5VTA4|uniprotkb:Q5VTA5|uniprotkb:Q9BU57|uniprotkb:Q9NYR4|uniprotkb:V9GYV9|ensembl:ENSP00000292035 psi-mi:grl1a_human(display_long)|uniprotkb:POLR2M(gene name)|psi-mi:POLR2M(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit M(gene name synonym)|uniprotkb:GRINL1A(gene name synonym)|uniprotkb:Glutamate receptor-like protein 1A(gene name synonym) psi-mi:med27_human(display_long)|uniprotkb:MED27(gene name)|psi-mi:MED27(display_short)|uniprotkb:Mediator complex subunit 27(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 8(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP34(gene name synonym)|uniprotkb:P37 TRAP/SMCC/PC2 subunit(gene name synonym)|uniprotkb:CRSP34(gene name synonym)|uniprotkb:CRSP8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482919|imex:IM-26985-423 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001018112.1|refseq:NP_056347.1|dip:DIP-61933N|ensembl:ENSG00000255529(gene)|ensembl:ENST00000299638(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051685"(maintenance of ER location)|interpro:IPR026213|mint:P0CAP2|rcsb pdb:6DRD refseq:NP_001240811.1|refseq:NP_004260.2|refseq:NP_001240810.1|dip:DIP-31465N|ensembl:ENSG00000160563(gene)|ensembl:ENST00000292035(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021627|mint:Q6P2C8|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 - - comment:"author score: 36" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:G0QVxeD0uvJTl0VPn+b3pV6zLe89606 rogid:V1clNhbtflCzCkC7OnaHGYrmQp89606 rigid:/44uHYNdWEgFUftM68YkL14pVXg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0CAP2 uniprotkb:Q15648 intact:EBI-9657655|uniprotkb:Q96NF5|uniprotkb:Q6EFN8|uniprotkb:Q6EEV3|uniprotkb:Q9Y3V6|uniprotkb:Q8NC58|uniprotkb:Q96DI5|uniprotkb:Q6EF02|uniprotkb:Q6K050|uniprotkb:Q6K046|uniprotkb:Q6K051|uniprotkb:Q6EF01|uniprotkb:Q6EES2|uniprotkb:Q8NCF3|uniprotkb:Q6EM48|uniprotkb:Q6EF46|uniprotkb:Q6ZQZ3|uniprotkb:Q6EER8|uniprotkb:Q96JB7|uniprotkb:Q6EF00|ensembl:ENSP00000299638 intact:EBI-394459|uniprotkb:A2RRQ6|uniprotkb:O43810|uniprotkb:O75447|uniprotkb:Q6P9H7|uniprotkb:Q6PK58|uniprotkb:Q9HD39|ensembl:ENSP00000300651 psi-mi:grl1a_human(display_long)|uniprotkb:POLR2M(gene name)|psi-mi:POLR2M(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit M(gene name synonym)|uniprotkb:GRINL1A(gene name synonym)|uniprotkb:Glutamate receptor-like protein 1A(gene name synonym) psi-mi:med1_human(display_long)|uniprotkb:TRIP2(gene name synonym)|uniprotkb:MED1(gene name)|psi-mi:MED1(display_short)|uniprotkb:ARC205(gene name synonym)|uniprotkb:DRIP205(gene name synonym)|uniprotkb:TRAP220(gene name synonym)|uniprotkb:Activator-recruited cofactor 205 kDa component(gene name synonym)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-binding protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 220 kDa component(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 2(gene name synonym)|uniprotkb:p53 regulatory protein RB18A(gene name synonym)|uniprotkb:Vitamin D receptor-interacting protein complex component DRIP205(gene name synonym)|uniprotkb:CRSP1(gene name synonym)|uniprotkb:CRSP200(gene name synonym)|uniprotkb:DRIP230(gene name synonym)|uniprotkb:PBP(gene name synonym)|uniprotkb:PPARBP(gene name synonym)|uniprotkb:PPARGBP(gene name synonym)|uniprotkb:RB18A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482919|imex:IM-26985-423 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001018112.1|refseq:NP_056347.1|dip:DIP-61933N|ensembl:ENSG00000255529(gene)|ensembl:ENST00000299638(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051685"(maintenance of ER location)|interpro:IPR026213|mint:P0CAP2|rcsb pdb:6DRD refseq:NP_004765.2|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR019680|mint:Q15648|rcsb pdb:1RJK|rcsb pdb:1RK3|rcsb pdb:1RKG|rcsb pdb:1RKH|rcsb pdb:2O4J|rcsb pdb:2O4R|rcsb pdb:2ZFX|rcsb pdb:3A2H|rcsb pdb:3AUN|rcsb pdb:3VJS|rcsb pdb:3VJT|rcsb pdb:3VRT|rcsb pdb:3VRU|rcsb pdb:3VRV|rcsb pdb:3VRW|rcsb pdb:3W0G|rcsb pdb:3W0H|rcsb pdb:3W0I|rcsb pdb:3W0J|rcsb pdb:3W5P|rcsb pdb:3W5Q|rcsb pdb:3W5R|rcsb pdb:3W5T|rcsb pdb:3WT5|rcsb pdb:3WT6|rcsb pdb:3WT7|rcsb pdb:3WTQ|rcsb pdb:4YNK|rcsb pdb:5AWJ|rcsb pdb:5AWK|rcsb pdb:5B41|rcsb pdb:5B5B|rcsb pdb:5GIC|rcsb pdb:5GID|rcsb pdb:5GIE|rcsb pdb:5XPM|rcsb pdb:5XPN|rcsb pdb:5XPO|rcsb pdb:5XPP|rcsb pdb:5XUQ|rcsb pdb:5XZF|rcsb pdb:5XZH|rcsb pdb:5ZWE|rcsb pdb:5ZWF|rcsb pdb:5ZWH|rcsb pdb:5ZWI|rcsb pdb:6D94|rcsb pdb:6JEZ|rcsb pdb:6K5O|rcsb pdb:6ONJ|rcsb pdb:7C7V|rcsb pdb:7C7W|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9707564|reactome:R-HSA-9707616|ensembl:ENSG00000125686(gene)|ensembl:ENST00000300651(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003406"(retinal pigment epithelium development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0050693"(LBD domain binding)|dip:DIP-24212N - - comment:"author score: 37" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:G0QVxeD0uvJTl0VPn+b3pV6zLe89606 rogid:A4EIAri9zYycSlTA7s6NzbOi9n49606 rigid:/44uHYNdWEgFUftM68YkL14pVXg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0CAP2 uniprotkb:Q9H944 intact:EBI-9657655|uniprotkb:Q96NF5|uniprotkb:Q6EFN8|uniprotkb:Q6EEV3|uniprotkb:Q9Y3V6|uniprotkb:Q8NC58|uniprotkb:Q96DI5|uniprotkb:Q6EF02|uniprotkb:Q6K050|uniprotkb:Q6K046|uniprotkb:Q6K051|uniprotkb:Q6EF01|uniprotkb:Q6EES2|uniprotkb:Q8NCF3|uniprotkb:Q6EM48|uniprotkb:Q6EF46|uniprotkb:Q6ZQZ3|uniprotkb:Q6EER8|uniprotkb:Q96JB7|uniprotkb:Q6EF00|ensembl:ENSP00000299638 intact:EBI-394644|uniprotkb:Q9Y429|uniprotkb:O95821|uniprotkb:Q5T8J4|uniprotkb:B4DE08|ensembl:ENSP00000265350 psi-mi:grl1a_human(display_long)|uniprotkb:POLR2M(gene name)|psi-mi:POLR2M(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit M(gene name synonym)|uniprotkb:GRINL1A(gene name synonym)|uniprotkb:Glutamate receptor-like protein 1A(gene name synonym) psi-mi:med20_human(display_long)|uniprotkb:TRFP(gene name synonym)|uniprotkb:MED20(gene name)|psi-mi:MED20(display_short)|uniprotkb:Mediator complex subunit 20(gene name synonym)|uniprotkb:TRF-proximal protein homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482919|imex:IM-26985-423 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001018112.1|refseq:NP_056347.1|dip:DIP-61933N|ensembl:ENSG00000255529(gene)|ensembl:ENST00000299638(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051685"(maintenance of ER location)|interpro:IPR026213|mint:P0CAP2|rcsb pdb:6DRD refseq:NP_004266.2|refseq:NP_001292384.1|refseq:NP_001292385.1|refseq:NP_001292386.1|go:"GO:0016592"(mediator complex)|interpro:IPR013921(TATA-binding related factor)|mint:Q9H944|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|ensembl:ENSG00000124641(gene)|ensembl:ENST00000265350(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|dip:DIP-31449N - - comment:"author score: 37" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:G0QVxeD0uvJTl0VPn+b3pV6zLe89606 rogid:MpYOrONH6+0lKIlO6J+Szjzkw2A9606 rigid:/44uHYNdWEgFUftM68YkL14pVXg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0CAP2 uniprotkb:O95402 intact:EBI-9657655|uniprotkb:Q96NF5|uniprotkb:Q6EFN8|uniprotkb:Q6EEV3|uniprotkb:Q9Y3V6|uniprotkb:Q8NC58|uniprotkb:Q96DI5|uniprotkb:Q6EF02|uniprotkb:Q6K050|uniprotkb:Q6K046|uniprotkb:Q6K051|uniprotkb:Q6EF01|uniprotkb:Q6EES2|uniprotkb:Q8NCF3|uniprotkb:Q6EM48|uniprotkb:Q6EF46|uniprotkb:Q6ZQZ3|uniprotkb:Q6EER8|uniprotkb:Q96JB7|uniprotkb:Q6EF00|ensembl:ENSP00000299638 intact:EBI-394392|uniprotkb:A1A4S3|uniprotkb:Q0VGB6|intact:EBI-28974475|ensembl:ENSP00000263390 psi-mi:grl1a_human(display_long)|uniprotkb:POLR2M(gene name)|psi-mi:POLR2M(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit M(gene name synonym)|uniprotkb:GRINL1A(gene name synonym)|uniprotkb:Glutamate receptor-like protein 1A(gene name synonym) psi-mi:med26_human(display_long)|uniprotkb:ARC70(gene name synonym)|uniprotkb:MED26(gene name)|psi-mi:MED26(display_short)|uniprotkb:Mediator complex subunit 26(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 7(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP70(gene name synonym)|uniprotkb:Activator-recruited cofactor 70 kDa component(gene name synonym)|uniprotkb:CRSP7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482919|imex:IM-26985-423 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001018112.1|refseq:NP_056347.1|dip:DIP-61933N|ensembl:ENSG00000255529(gene)|ensembl:ENST00000299638(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051685"(maintenance of ER location)|interpro:IPR026213|mint:P0CAP2|rcsb pdb:6DRD ensembl:ENSP00000263390|ensembl:ENST00000611692|ensembl:ENSP00000484490|refseq:NP_004822.2|ensembl:ENSG00000105085(gene)|ensembl:ENST00000263390(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016592"(mediator complex)|go:"GO:0070847"(core mediator complex)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR017923|interpro:IPR031416|interpro:IPR031417|interpro:IPR035441|interpro:IPR042376|mint:O95402|rcsb pdb:5ODD|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31464N - - comment:"author score: 38" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:G0QVxeD0uvJTl0VPn+b3pV6zLe89606 rogid:1kRmQ+QH5uQkKVfjo2Rc2SkAyKc9606 rigid:/44uHYNdWEgFUftM68YkL14pVXg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0CAP2 uniprotkb:Q9NVC6 intact:EBI-9657655|uniprotkb:Q96NF5|uniprotkb:Q6EFN8|uniprotkb:Q6EEV3|uniprotkb:Q9Y3V6|uniprotkb:Q8NC58|uniprotkb:Q96DI5|uniprotkb:Q6EF02|uniprotkb:Q6K050|uniprotkb:Q6K046|uniprotkb:Q6K051|uniprotkb:Q6EF01|uniprotkb:Q6EES2|uniprotkb:Q8NCF3|uniprotkb:Q6EM48|uniprotkb:Q6EF46|uniprotkb:Q6ZQZ3|uniprotkb:Q6EER8|uniprotkb:Q96JB7|uniprotkb:Q6EF00|ensembl:ENSP00000299638 intact:EBI-394562|uniprotkb:Q9HA81|uniprotkb:Q9UNP7|uniprotkb:Q9Y2W0|uniprotkb:Q9Y660|uniprotkb:B3KN07|ensembl:ENSP00000251871 psi-mi:grl1a_human(display_long)|uniprotkb:POLR2M(gene name)|psi-mi:POLR2M(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit M(gene name synonym)|uniprotkb:GRINL1A(gene name synonym)|uniprotkb:Glutamate receptor-like protein 1A(gene name synonym) psi-mi:med17_human(display_long)|uniprotkb:TRAP80(gene name synonym)|uniprotkb:MED17(gene name)|psi-mi:MED17(display_short)|uniprotkb:ARC77(gene name synonym)|uniprotkb:DRIP80(gene name synonym)|uniprotkb:Mediator complex subunit 17(gene name synonym)|uniprotkb:Cofactor required for Sp1 transcriptional activation subunit 6(gene name synonym)|uniprotkb:Transcriptional coactivator CRSP77(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 80 kDa component(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 80 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 77 kDa component(gene name synonym)|uniprotkb:CRSP6(gene name synonym)|uniprotkb:DRIP77(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482919|imex:IM-26985-423 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001018112.1|refseq:NP_056347.1|dip:DIP-61933N|ensembl:ENSG00000255529(gene)|ensembl:ENST00000299638(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051685"(maintenance of ER location)|interpro:IPR026213|mint:P0CAP2|rcsb pdb:6DRD refseq:NP_004259.3|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|ensembl:ENSG00000042429(gene)|ensembl:ENST00000251871(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019313|mint:Q9NVC6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|dip:DIP-31451N - - comment:"author score: 40" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:G0QVxeD0uvJTl0VPn+b3pV6zLe89606 rogid:P2hRQOjWEtjw5V+lt7J9TP3VbpU9606 rigid:/44uHYNdWEgFUftM68YkL14pVXg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0CAP2 uniprotkb:Q9NPJ6 intact:EBI-9657655|uniprotkb:Q96NF5|uniprotkb:Q6EFN8|uniprotkb:Q6EEV3|uniprotkb:Q9Y3V6|uniprotkb:Q8NC58|uniprotkb:Q96DI5|uniprotkb:Q6EF02|uniprotkb:Q6K050|uniprotkb:Q6K046|uniprotkb:Q6K051|uniprotkb:Q6EF01|uniprotkb:Q6EES2|uniprotkb:Q8NCF3|uniprotkb:Q6EM48|uniprotkb:Q6EF46|uniprotkb:Q6ZQZ3|uniprotkb:Q6EER8|uniprotkb:Q96JB7|uniprotkb:Q6EF00|ensembl:ENSP00000299638 intact:EBI-394607|uniprotkb:Q9BS95|uniprotkb:Q9NYR5|uniprotkb:Q53GB4|uniprotkb:Q53H68|uniprotkb:Q5T912|uniprotkb:Q6FHC4|uniprotkb:Q6IA79|uniprotkb:B4DX67|ensembl:ENSP00000258648 psi-mi:grl1a_human(display_long)|uniprotkb:POLR2M(gene name)|psi-mi:POLR2M(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit M(gene name synonym)|uniprotkb:GRINL1A(gene name synonym)|uniprotkb:Glutamate receptor-like protein 1A(gene name synonym) psi-mi:med4_human(display_long)|uniprotkb:HSPC126(orf name)|uniprotkb:DRIP36(gene name synonym)|uniprotkb:MED4(gene name)|psi-mi:MED4(display_short)|uniprotkb:ARC36(gene name synonym)|uniprotkb:Mediator complex subunit 4(gene name synonym)|uniprotkb:Vitamin D3 receptor-interacting protein complex 36 kDa component(gene name synonym)|uniprotkb:Activator-recruited cofactor 36 kDa component(gene name synonym)|uniprotkb:TRAP/SMCC/PC2 subunit p36 subunit(gene name synonym)|uniprotkb:VDRIP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482919|imex:IM-26985-423 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001018112.1|refseq:NP_056347.1|dip:DIP-61933N|ensembl:ENSG00000255529(gene)|ensembl:ENST00000299638(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051685"(maintenance of ER location)|interpro:IPR026213|mint:P0CAP2|rcsb pdb:6DRD refseq:NP_001257558.1|refseq:NP_054885.1|ensembl:ENSG00000136146(gene)|ensembl:ENST00000258648(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0070847"(core mediator complex)|interpro:IPR019258|mint:Q9NPJ6|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340 - - comment:"author score: 44" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:G0QVxeD0uvJTl0VPn+b3pV6zLe89606 rogid:Bept2Oec50gruA9e4pf+eEUiANM9606 rigid:/44uHYNdWEgFUftM68YkL14pVXg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0CAP2 uniprotkb:Q9H204 intact:EBI-9657655|uniprotkb:Q96NF5|uniprotkb:Q6EFN8|uniprotkb:Q6EEV3|uniprotkb:Q9Y3V6|uniprotkb:Q8NC58|uniprotkb:Q96DI5|uniprotkb:Q6EF02|uniprotkb:Q6K050|uniprotkb:Q6K046|uniprotkb:Q6K051|uniprotkb:Q6EF01|uniprotkb:Q6EES2|uniprotkb:Q8NCF3|uniprotkb:Q6EM48|uniprotkb:Q6EF46|uniprotkb:Q6ZQZ3|uniprotkb:Q6EER8|uniprotkb:Q96JB7|uniprotkb:Q6EF00|ensembl:ENSP00000299638 intact:EBI-514199|uniprotkb:Q9BZJ5|ensembl:ENSP00000237380 psi-mi:grl1a_human(display_long)|uniprotkb:POLR2M(gene name)|psi-mi:POLR2M(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit M(gene name synonym)|uniprotkb:GRINL1A(gene name synonym)|uniprotkb:Glutamate receptor-like protein 1A(gene name synonym) psi-mi:med28_human(display_long)|uniprotkb:Mediator complex subunit 28(gene name synonym)|uniprotkb:Tumor angiogenesis marker EG-1(gene name synonym)|uniprotkb:Endothelial-derived protein 1(gene name synonym)|uniprotkb:Merlin and Grb2-interacting cytoskeletal protein(gene name synonym)|uniprotkb:MED28(gene name)|psi-mi:MED28(display_short)|uniprotkb:EG1(gene name synonym)|uniprotkb:FKSG20(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482919|imex:IM-26985-423 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001018112.1|refseq:NP_056347.1|dip:DIP-61933N|ensembl:ENSG00000255529(gene)|ensembl:ENST00000299638(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051685"(maintenance of ER location)|interpro:IPR026213|mint:P0CAP2|rcsb pdb:6DRD refseq:NP_079481.2|ensembl:ENSG00000118579(gene)|ensembl:ENST00000237380(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0051151"(negative regulation of smooth muscle cell differentiation)|interpro:IPR021640|mint:Q9H204|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340 - - comment:"author score: 44" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:G0QVxeD0uvJTl0VPn+b3pV6zLe89606 rogid:1gt/0vP7vWJ+M1fU+qZPcWGj34U9606 rigid:/44uHYNdWEgFUftM68YkL14pVXg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0CAP2 uniprotkb:Q13503 intact:EBI-9657655|uniprotkb:Q96NF5|uniprotkb:Q6EFN8|uniprotkb:Q6EEV3|uniprotkb:Q9Y3V6|uniprotkb:Q8NC58|uniprotkb:Q96DI5|uniprotkb:Q6EF02|uniprotkb:Q6K050|uniprotkb:Q6K046|uniprotkb:Q6K051|uniprotkb:Q6EF01|uniprotkb:Q6EES2|uniprotkb:Q8NCF3|uniprotkb:Q6EM48|uniprotkb:Q6EF46|uniprotkb:Q6ZQZ3|uniprotkb:Q6EER8|uniprotkb:Q96JB7|uniprotkb:Q6EF00|ensembl:ENSP00000299638 intact:EBI-394678|uniprotkb:Q6IB05|uniprotkb:Q92811|uniprotkb:B2R4I3|ensembl:ENSP00000282892 psi-mi:grl1a_human(display_long)|uniprotkb:POLR2M(gene name)|psi-mi:POLR2M(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit M(gene name synonym)|uniprotkb:GRINL1A(gene name synonym)|uniprotkb:Glutamate receptor-like protein 1A(gene name synonym) psi-mi:med21_human(display_long)|uniprotkb:SRB7(gene name synonym)|uniprotkb:MED21(gene name)|psi-mi:MED21(display_short)|uniprotkb:Mediator complex subunit 21(gene name synonym)|uniprotkb:RNA polymerase II holoenzyme component SRB7(gene name synonym)|uniprotkb:SURB7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482919|imex:IM-26985-423 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001018112.1|refseq:NP_056347.1|dip:DIP-61933N|ensembl:ENSG00000255529(gene)|ensembl:ENST00000299638(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051685"(maintenance of ER location)|interpro:IPR026213|mint:P0CAP2|rcsb pdb:6DRD refseq:NP_004255.2|ensembl:ENSG00000152944(gene)|ensembl:ENST00000282892(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016592"(mediator complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR021384|interpro:IPR037212|mint:Q13503|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-381340|dip:DIP-31471N - - comment:"author score: 47" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:G0QVxeD0uvJTl0VPn+b3pV6zLe89606 rogid:qNrBcd6tolQzcRyFK/OdD3P1Q3g9606 rigid:/44uHYNdWEgFUftM68YkL14pVXg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0CAP2 uniprotkb:Q9BTT4 intact:EBI-9657655|uniprotkb:Q96NF5|uniprotkb:Q6EFN8|uniprotkb:Q6EEV3|uniprotkb:Q9Y3V6|uniprotkb:Q8NC58|uniprotkb:Q96DI5|uniprotkb:Q6EF02|uniprotkb:Q6K050|uniprotkb:Q6K046|uniprotkb:Q6K051|uniprotkb:Q6EF01|uniprotkb:Q6EES2|uniprotkb:Q8NCF3|uniprotkb:Q6EM48|uniprotkb:Q6EF46|uniprotkb:Q6ZQZ3|uniprotkb:Q6EER8|uniprotkb:Q96JB7|uniprotkb:Q6EF00|ensembl:ENSP00000299638 intact:EBI-394354|uniprotkb:C6G491|ensembl:ENSP00000255764 psi-mi:grl1a_human(display_long)|uniprotkb:POLR2M(gene name)|psi-mi:POLR2M(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit M(gene name synonym)|uniprotkb:GRINL1A(gene name synonym)|uniprotkb:Glutamate receptor-like protein 1A(gene name synonym) psi-mi:med10_human(display_long)|uniprotkb:MED10(gene name)|psi-mi:MED10(display_short)|uniprotkb:L6(orf name)|uniprotkb:TRG17(orf name)|uniprotkb:Mediator complex subunit 10(gene name synonym)|uniprotkb:Transformation-related gene 17 protein(gene name synonym)|uniprotkb:Transformation-related gene 20 protein(gene name synonym)|uniprotkb:TRG20(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482919|imex:IM-26985-423 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001018112.1|refseq:NP_056347.1|dip:DIP-61933N|ensembl:ENSG00000255529(gene)|ensembl:ENST00000299638(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051685"(maintenance of ER location)|interpro:IPR026213|mint:P0CAP2|rcsb pdb:6DRD ensembl:ENSG00000133398(gene)|ensembl:ENST00000255764(transcript)|refseq:NP_115662.2|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016592"(mediator complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR019145|mint:Q9BTT4|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|rcsb pdb:7LBM|rcsb pdb:7NVR|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-381340|go:"GO:0000151"(ubiquitin ligase complex)|dip:DIP-31457N - - comment:"author score: 53" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:G0QVxeD0uvJTl0VPn+b3pV6zLe89606 rogid:LzJW7C8kl2pWmffOjo8S/FNSS9I9606 rigid:/44uHYNdWEgFUftM68YkL14pVXg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0CAP2 uniprotkb:O94762 intact:EBI-9657655|uniprotkb:Q96NF5|uniprotkb:Q6EFN8|uniprotkb:Q6EEV3|uniprotkb:Q9Y3V6|uniprotkb:Q8NC58|uniprotkb:Q96DI5|uniprotkb:Q6EF02|uniprotkb:Q6K050|uniprotkb:Q6K046|uniprotkb:Q6K051|uniprotkb:Q6EF01|uniprotkb:Q6EES2|uniprotkb:Q8NCF3|uniprotkb:Q6EM48|uniprotkb:Q6EF46|uniprotkb:Q6ZQZ3|uniprotkb:Q6EER8|uniprotkb:Q96JB7|uniprotkb:Q6EF00|ensembl:ENSP00000299638 intact:EBI-395321|ensembl:ENSP00000317636|uniprotkb:Q9P1W7|uniprotkb:Q9UNC8|uniprotkb:Q9H0B1|uniprotkb:Q6P4G0 psi-mi:grl1a_human(display_long)|uniprotkb:POLR2M(gene name)|psi-mi:POLR2M(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit M(gene name synonym)|uniprotkb:GRINL1A(gene name synonym)|uniprotkb:Glutamate receptor-like protein 1A(gene name synonym) psi-mi:recq5_human(display_long)|uniprotkb:RECQ5(gene name synonym)|uniprotkb:RECQL5(gene name)|psi-mi:RECQL5(display_short)|uniprotkb:RecQ protein-like 5(gene name synonym)|uniprotkb:DNA helicase, RecQ-like type 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482919|imex:IM-26985-423 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001018112.1|refseq:NP_056347.1|dip:DIP-61933N|ensembl:ENSG00000255529(gene)|ensembl:ENST00000299638(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051685"(maintenance of ER location)|interpro:IPR026213|mint:P0CAP2|rcsb pdb:6DRD ensembl:ENSG00000108469(gene)|ensembl:ENST00000317905(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006260"(DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0051301"(cell division)|go:"GO:0051304"(chromosome separation)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR010716(RecQ helicase-like 5)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR032284|interpro:IPR001650(DNA/RNA helicase, C-terminal)|refseq:NP_001003715.1|refseq:NP_001003716.1|refseq:NP_004250.4|mint:O94762|rcsb pdb:4BK0|rcsb pdb:5LB3|rcsb pdb:5LB5|rcsb pdb:5LB8|rcsb pdb:5LBA|refseq:XP_016880832.1|refseq:XP_016880833.1|dip:DIP-32964N - - comment:"author score: 59" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:G0QVxeD0uvJTl0VPn+b3pV6zLe89606 rogid:lOMr1rIrRi78aQO2pQod/1V3Ku49606 rigid:/44uHYNdWEgFUftM68YkL14pVXg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0CAP2 uniprotkb:P62875 intact:EBI-9657655|uniprotkb:Q96NF5|uniprotkb:Q6EFN8|uniprotkb:Q6EEV3|uniprotkb:Q9Y3V6|uniprotkb:Q8NC58|uniprotkb:Q96DI5|uniprotkb:Q6EF02|uniprotkb:Q6K050|uniprotkb:Q6K046|uniprotkb:Q6K051|uniprotkb:Q6EF01|uniprotkb:Q6EES2|uniprotkb:Q8NCF3|uniprotkb:Q6EM48|uniprotkb:Q6EF46|uniprotkb:Q6ZQZ3|uniprotkb:Q6EER8|uniprotkb:Q96JB7|uniprotkb:Q6EF00|ensembl:ENSP00000299638 intact:EBI-359527|ensembl:ENSP00000324124|ensembl:ENSP00000432807|uniprotkb:P52436|uniprotkb:Q6FHX3 psi-mi:grl1a_human(display_long)|uniprotkb:POLR2M(gene name)|psi-mi:POLR2M(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit M(gene name synonym)|uniprotkb:GRINL1A(gene name synonym)|uniprotkb:Glutamate receptor-like protein 1A(gene name synonym) psi-mi:rpab5_human(display_long)|uniprotkb:POLR2L(gene name)|psi-mi:POLR2L(display_short)|uniprotkb:DNA-directed RNA polymerase III subunit L(gene name synonym)|uniprotkb:RPB10 homolog(gene name synonym)|uniprotkb:RNA polymerase II 7.6 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482919|imex:IM-26985-423 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001018112.1|refseq:NP_056347.1|dip:DIP-61933N|ensembl:ENSG00000255529(gene)|ensembl:ENST00000299638(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051685"(maintenance of ER location)|interpro:IPR026213|mint:P0CAP2|rcsb pdb:6DRD ensembl:ENSG00000177700(gene)|ensembl:ENST00000322028(transcript)|ensembl:ENST00000534030(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006356"(regulation of transcription by RNA polymerase I)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR000268(RNA polymerases, N/8 Kd subunits)|interpro:IPR020789|interpro:IPR023580|mint:P62875|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|refseq:NP_066951.1|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-75955|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-203927|dip:DIP-32960N - - comment:"author score: 84" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:G0QVxeD0uvJTl0VPn+b3pV6zLe89606 rogid:uDzgKgHzFTPxFaV1GeUYdYMa4Gk9606 rigid:/44uHYNdWEgFUftM68YkL14pVXg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0CAP2 uniprotkb:Q5VT52 intact:EBI-9657655|uniprotkb:Q96NF5|uniprotkb:Q6EFN8|uniprotkb:Q6EEV3|uniprotkb:Q9Y3V6|uniprotkb:Q8NC58|uniprotkb:Q96DI5|uniprotkb:Q6EF02|uniprotkb:Q6K050|uniprotkb:Q6K046|uniprotkb:Q6K051|uniprotkb:Q6EF01|uniprotkb:Q6EES2|uniprotkb:Q8NCF3|uniprotkb:Q6EM48|uniprotkb:Q6EF46|uniprotkb:Q6ZQZ3|uniprotkb:Q6EER8|uniprotkb:Q96JB7|uniprotkb:Q6EF00|ensembl:ENSP00000299638 intact:EBI-372367|uniprotkb:O75048|uniprotkb:Q5VT53|uniprotkb:Q6MZL4|uniprotkb:Q86XD2|uniprotkb:A8K6N8|uniprotkb:B3KPT1|uniprotkb:Q5VT51|uniprotkb:Q9P0D7|uniprotkb:B4E2Q6|ensembl:ENSP00000358064 psi-mi:grl1a_human(display_long)|uniprotkb:POLR2M(gene name)|psi-mi:POLR2M(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit M(gene name synonym)|uniprotkb:GRINL1A(gene name synonym)|uniprotkb:Glutamate receptor-like protein 1A(gene name synonym) psi-mi:rprd2_human(display_long)|uniprotkb:RPRD2(gene name)|psi-mi:RPRD2(display_short)|uniprotkb:KIAA0460(gene name synonym)|uniprotkb:HSPC099(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482919|imex:IM-26985-423 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001018112.1|refseq:NP_056347.1|dip:DIP-61933N|ensembl:ENSG00000255529(gene)|ensembl:ENST00000299638(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051685"(maintenance of ER location)|interpro:IPR026213|mint:P0CAP2|rcsb pdb:6DRD refseq:NP_056018.2|ensembl:ENSG00000163125(gene)|ensembl:ENST00000369068(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q5VT52|rcsb pdb:4FLB|reactome:R-HSA-6807505|refseq:NP_001284602.1|refseq:NP_001284603.1|dip:DIP-31155N - - comment:"author score: 113" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:G0QVxeD0uvJTl0VPn+b3pV6zLe89606 rogid:HbkwBBEJ+MNQOjJ2nezU7MJMHYQ9606 rigid:/44uHYNdWEgFUftM68YkL14pVXg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0CAP2 uniprotkb:P52435 intact:EBI-9657655|uniprotkb:Q96NF5|uniprotkb:Q6EFN8|uniprotkb:Q6EEV3|uniprotkb:Q9Y3V6|uniprotkb:Q8NC58|uniprotkb:Q96DI5|uniprotkb:Q6EF02|uniprotkb:Q6K050|uniprotkb:Q6K046|uniprotkb:Q6K051|uniprotkb:Q6EF01|uniprotkb:Q6EES2|uniprotkb:Q8NCF3|uniprotkb:Q6EM48|uniprotkb:Q6EF46|uniprotkb:Q6ZQZ3|uniprotkb:Q6EER8|uniprotkb:Q96JB7|uniprotkb:Q6EF00|ensembl:ENSP00000299638 intact:EBI-394753|uniprotkb:O43375|uniprotkb:A5D6V8|ensembl:ENSP00000292614 psi-mi:grl1a_human(display_long)|uniprotkb:POLR2M(gene name)|psi-mi:POLR2M(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit M(gene name synonym)|uniprotkb:GRINL1A(gene name synonym)|uniprotkb:Glutamate receptor-like protein 1A(gene name synonym) psi-mi:rpb11_human(display_long)|uniprotkb:POLR2J(gene name)|psi-mi:POLR2J(display_short)|uniprotkb:POLR2J1(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II subunit J-1(gene name synonym)|uniprotkb:RNA polymerase II 13.3 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482919|imex:IM-26985-423 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001018112.1|refseq:NP_056347.1|dip:DIP-61933N|ensembl:ENSG00000255529(gene)|ensembl:ENST00000299638(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051685"(maintenance of ER location)|interpro:IPR026213|mint:P0CAP2|rcsb pdb:6DRD refseq:NP_006225.1|ensembl:ENSG00000005075(gene)|ensembl:ENST00000292614(transcript)|go:"GO:0001055"(RNA polymerase II activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0030275"(LRR domain binding)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR008193(DNA-directed RNA polymerase Rpb11, 13-16 kDa subunit, conserved site)|interpro:IPR009025(DNA-directed RNA polymerase, RBP11-like)|interpro:IPR036603|interpro:IPR037685|mint:P52435|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32913N - - comment:"author score: 146" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:G0QVxeD0uvJTl0VPn+b3pV6zLe89606 rogid:jK/DlwFrHHuEJ0Ns3wRoB3icmsA9606 rigid:/44uHYNdWEgFUftM68YkL14pVXg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0CAP2 uniprotkb:P30876 intact:EBI-9657655|uniprotkb:Q96NF5|uniprotkb:Q6EFN8|uniprotkb:Q6EEV3|uniprotkb:Q9Y3V6|uniprotkb:Q8NC58|uniprotkb:Q96DI5|uniprotkb:Q6EF02|uniprotkb:Q6K050|uniprotkb:Q6K046|uniprotkb:Q6K051|uniprotkb:Q6EF01|uniprotkb:Q6EES2|uniprotkb:Q8NCF3|uniprotkb:Q6EM48|uniprotkb:Q6EF46|uniprotkb:Q6ZQZ3|uniprotkb:Q6EER8|uniprotkb:Q96JB7|uniprotkb:Q6EF00|ensembl:ENSP00000299638 intact:EBI-394712|uniprotkb:Q8IZ61|uniprotkb:A8K1A8|ensembl:ENSP00000312735|ensembl:ENSP00000370625 psi-mi:grl1a_human(display_long)|uniprotkb:POLR2M(gene name)|psi-mi:POLR2M(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit M(gene name synonym)|uniprotkb:GRINL1A(gene name synonym)|uniprotkb:Glutamate receptor-like protein 1A(gene name synonym) psi-mi:rpb2_human(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit B(gene name synonym)|uniprotkb:RNA polymerase II subunit B2(gene name synonym)|uniprotkb:RNA polymerase II subunit 2(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 140 kDa polypeptide(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482919|imex:IM-26985-423 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001018112.1|refseq:NP_056347.1|dip:DIP-61933N|ensembl:ENSG00000255529(gene)|ensembl:ENST00000299638(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051685"(maintenance of ER location)|interpro:IPR026213|mint:P0CAP2|rcsb pdb:6DRD refseq:NP_000929.1|refseq:NP_001290197.1|refseq:NP_001290198.1|ensembl:ENSG00000047315(gene)|ensembl:ENST00000314595(transcript)|ensembl:ENST00000381227(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|mint:P30876|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32910N - - comment:"author score: 151" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:G0QVxeD0uvJTl0VPn+b3pV6zLe89606 rogid:YhEjtfLk2QnbRPefOp8ZHX0ejak9606 rigid:/44uHYNdWEgFUftM68YkL14pVXg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0CAP2 uniprotkb:P24928 intact:EBI-9657655|uniprotkb:Q96NF5|uniprotkb:Q6EFN8|uniprotkb:Q6EEV3|uniprotkb:Q9Y3V6|uniprotkb:Q8NC58|uniprotkb:Q96DI5|uniprotkb:Q6EF02|uniprotkb:Q6K050|uniprotkb:Q6K046|uniprotkb:Q6K051|uniprotkb:Q6EF01|uniprotkb:Q6EES2|uniprotkb:Q8NCF3|uniprotkb:Q6EM48|uniprotkb:Q6EF46|uniprotkb:Q6ZQZ3|uniprotkb:Q6EER8|uniprotkb:Q96JB7|uniprotkb:Q6EF00|ensembl:ENSP00000299638 intact:EBI-295301|uniprotkb:A6NN93|uniprotkb:B9EH88|uniprotkb:Q6NX41|intact:EBI-17957133|intact:EBI-14758660|intact:EBI-13324911|intact:EBI-23311874 psi-mi:grl1a_human(display_long)|uniprotkb:POLR2M(gene name)|psi-mi:POLR2M(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit M(gene name synonym)|uniprotkb:GRINL1A(gene name synonym)|uniprotkb:Glutamate receptor-like protein 1A(gene name synonym) psi-mi:rpb1_human(display_long)|uniprotkb:POLR2A(gene name)|psi-mi:POLR2A(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit A(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:POLR2(gene name synonym)|uniprotkb:RNA-directed RNA polymerase II subunit RPB1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482919|imex:IM-26985-423 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001018112.1|refseq:NP_056347.1|dip:DIP-61933N|ensembl:ENSG00000255529(gene)|ensembl:ENST00000299638(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051685"(maintenance of ER location)|interpro:IPR026213|mint:P0CAP2|rcsb pdb:6DRD refseq:NP_000928.1|mint:P24928|dip:DIP-29011N|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0019900"(kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:2GHQ|rcsb pdb:2GHT|rcsb pdb:2LTO|rcsb pdb:3D9K|rcsb pdb:3D9L|rcsb pdb:3D9M|rcsb pdb:3D9N|rcsb pdb:3D9O|rcsb pdb:3D9P|rcsb pdb:4JXT|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:5M3H|rcsb pdb:5M3J|rcsb pdb:6DRD|rcsb pdb:6F5P|rcsb pdb:6G0R|rcsb pdb:6IC8|rcsb pdb:6IC9|rcsb pdb:6O9L|rcsb pdb:6Q5Y|rcsb pdb:6XKB|rcsb pdb:6XRE|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095 - - comment:"author score: 154" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:G0QVxeD0uvJTl0VPn+b3pV6zLe89606 rogid:Si2fgh4AMaNtlzvSQhvsuPusX7s9606 rigid:/44uHYNdWEgFUftM68YkL14pVXg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0CAP2 uniprotkb:P62487 intact:EBI-9657655|uniprotkb:Q96NF5|uniprotkb:Q6EFN8|uniprotkb:Q6EEV3|uniprotkb:Q9Y3V6|uniprotkb:Q8NC58|uniprotkb:Q96DI5|uniprotkb:Q6EF02|uniprotkb:Q6K050|uniprotkb:Q6K046|uniprotkb:Q6K051|uniprotkb:Q6EF01|uniprotkb:Q6EES2|uniprotkb:Q8NCF3|uniprotkb:Q6EM48|uniprotkb:Q6EF46|uniprotkb:Q6ZQZ3|uniprotkb:Q6EER8|uniprotkb:Q96JB7|uniprotkb:Q6EF00|ensembl:ENSP00000299638 intact:EBI-347928|ensembl:ENSP00000301788|uniprotkb:P52433|uniprotkb:Q2M1Z4|uniprotkb:B2R5C0 psi-mi:grl1a_human(display_long)|uniprotkb:POLR2M(gene name)|psi-mi:POLR2M(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit M(gene name synonym)|uniprotkb:GRINL1A(gene name synonym)|uniprotkb:Glutamate receptor-like protein 1A(gene name synonym) psi-mi:rpb7_human(display_long)|uniprotkb:POLR2G(gene name)|psi-mi:POLR2G(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit G(gene name synonym)|uniprotkb:RPB7(gene name synonym)|uniprotkb:RNA polymerase II 19 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482919|imex:IM-26985-423 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001018112.1|refseq:NP_056347.1|dip:DIP-61933N|ensembl:ENSG00000255529(gene)|ensembl:ENST00000299638(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051685"(maintenance of ER location)|interpro:IPR026213|mint:P0CAP2|rcsb pdb:6DRD ensembl:ENSG00000168002(gene)|ensembl:ENST00000301788(transcript)|go:"GO:0000291"(nuclear-transcribed mRNA catabolic process, exonucleolytic)|go:"GO:0000932"(P-body)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006915"(apoptotic process)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR003029(S1, RNA binding)|interpro:IPR005576(RNA polymerase Rpb7, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR036898|mint:P62487|rcsb pdb:2C35|rcsb pdb:5IYA|rcsb pdb:5IY6|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|rcsb pdb:5IY7|reactome:R-HSA-167200|reactome:R-HSA-167238|rcsb pdb:5IY8|rcsb pdb:5IY9|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-5601884|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|refseq:NP_002687.1|dip:DIP-32663N - - comment:"author score: 155" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:G0QVxeD0uvJTl0VPn+b3pV6zLe89606 rogid:MtnIweuhSqLFov0c40uOiwv8Eas9606 rigid:/44uHYNdWEgFUftM68YkL14pVXg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0CAP2 uniprotkb:P19387 intact:EBI-9657655|uniprotkb:Q96NF5|uniprotkb:Q6EFN8|uniprotkb:Q6EEV3|uniprotkb:Q9Y3V6|uniprotkb:Q8NC58|uniprotkb:Q96DI5|uniprotkb:Q6EF02|uniprotkb:Q6K050|uniprotkb:Q6K046|uniprotkb:Q6K051|uniprotkb:Q6EF01|uniprotkb:Q6EES2|uniprotkb:Q8NCF3|uniprotkb:Q6EM48|uniprotkb:Q6EF46|uniprotkb:Q6ZQZ3|uniprotkb:Q6EER8|uniprotkb:Q96JB7|uniprotkb:Q6EF00|ensembl:ENSP00000299638 intact:EBI-394729|uniprotkb:O15161|ensembl:ENSP00000219252 psi-mi:grl1a_human(display_long)|uniprotkb:POLR2M(gene name)|psi-mi:POLR2M(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit M(gene name synonym)|uniprotkb:GRINL1A(gene name synonym)|uniprotkb:Glutamate receptor-like protein 1A(gene name synonym) psi-mi:rpb3_human(display_long)|uniprotkb:POLR2C(gene name)|psi-mi:POLR2C(display_short)|uniprotkb:A-152E5.7(orf name)|uniprotkb:DNA-directed RNA polymerase II subunit C(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 33 kDa polypeptide(gene name synonym)|uniprotkb:RPB31(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482919|imex:IM-26985-423 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001018112.1|refseq:NP_056347.1|dip:DIP-61933N|ensembl:ENSG00000255529(gene)|ensembl:ENST00000299638(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051685"(maintenance of ER location)|interpro:IPR026213|mint:P0CAP2|rcsb pdb:6DRD refseq:NP_116558.1|ensembl:ENSG00000102978(gene)|ensembl:ENST00000219252(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001514(DNA-directed RNA polymerase, 30-40 kDa subunit, conserved site)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR036603|interpro:IPR036643|mint:P19387|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32911N - - comment:"author score: 165" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:G0QVxeD0uvJTl0VPn+b3pV6zLe89606 rogid:UXFC+i+QqB2WRgL9OiYSQ66L36c9606 rigid:/44uHYNdWEgFUftM68YkL14pVXg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0CAP2 uniprotkb:P36954 intact:EBI-9657655|uniprotkb:Q96NF5|uniprotkb:Q6EFN8|uniprotkb:Q6EEV3|uniprotkb:Q9Y3V6|uniprotkb:Q8NC58|uniprotkb:Q96DI5|uniprotkb:Q6EF02|uniprotkb:Q6K050|uniprotkb:Q6K046|uniprotkb:Q6K051|uniprotkb:Q6EF01|uniprotkb:Q6EES2|uniprotkb:Q8NCF3|uniprotkb:Q6EM48|uniprotkb:Q6EF46|uniprotkb:Q6ZQZ3|uniprotkb:Q6EER8|uniprotkb:Q96JB7|uniprotkb:Q6EF00|ensembl:ENSP00000299638 intact:EBI-395202|uniprotkb:Q6NW05|uniprotkb:B2R5J2|ensembl:ENSP00000221859 psi-mi:grl1a_human(display_long)|uniprotkb:POLR2M(gene name)|psi-mi:POLR2M(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit M(gene name synonym)|uniprotkb:GRINL1A(gene name synonym)|uniprotkb:Glutamate receptor-like protein 1A(gene name synonym) psi-mi:rpb9_human(display_long)|uniprotkb:POLR2I(gene name)|psi-mi:POLR2I(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit I(gene name synonym)|uniprotkb:RNA polymerase II 14.5 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482919|imex:IM-26985-423 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001018112.1|refseq:NP_056347.1|dip:DIP-61933N|ensembl:ENSG00000255529(gene)|ensembl:ENST00000299638(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051685"(maintenance of ER location)|interpro:IPR026213|mint:P0CAP2|rcsb pdb:6DRD refseq:NP_006224.1|ensembl:ENSG00000105258(gene)|ensembl:ENST00000221859(transcript)|go:"GO:0001193"(maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034012|mint:P36954|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32917N - - comment:"author score: 179" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:G0QVxeD0uvJTl0VPn+b3pV6zLe89606 rogid:YZUW2UDzj1RhCC46iaX1LvYayNA9606 rigid:/44uHYNdWEgFUftM68YkL14pVXg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P0CAP2 uniprotkb:P52434 intact:EBI-9657655|uniprotkb:Q96NF5|uniprotkb:Q6EFN8|uniprotkb:Q6EEV3|uniprotkb:Q9Y3V6|uniprotkb:Q8NC58|uniprotkb:Q96DI5|uniprotkb:Q6EF02|uniprotkb:Q6K050|uniprotkb:Q6K046|uniprotkb:Q6K051|uniprotkb:Q6EF01|uniprotkb:Q6EES2|uniprotkb:Q8NCF3|uniprotkb:Q6EM48|uniprotkb:Q6EF46|uniprotkb:Q6ZQZ3|uniprotkb:Q6EER8|uniprotkb:Q96JB7|uniprotkb:Q6EF00|ensembl:ENSP00000299638 intact:EBI-359505|uniprotkb:P53802|uniprotkb:Q969R0|ensembl:ENSP00000392913|uniprotkb:C9J413|uniprotkb:C9JBJ6|uniprotkb:C9JCU7|uniprotkb:C9JUA8 psi-mi:grl1a_human(display_long)|uniprotkb:POLR2M(gene name)|psi-mi:POLR2M(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit M(gene name synonym)|uniprotkb:GRINL1A(gene name synonym)|uniprotkb:Glutamate receptor-like protein 1A(gene name synonym) psi-mi:rpab3_human(display_long)|uniprotkb:POLR2H(gene name)|psi-mi:POLR2H(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit H(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I, II, and III 17.1 kDa polypeptide(gene name synonym)|uniprotkb:RPB17(gene name synonym)|uniprotkb:RPB8 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25482919|imex:IM-26985-423 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001018112.1|refseq:NP_056347.1|dip:DIP-61933N|ensembl:ENSG00000255529(gene)|ensembl:ENST00000299638(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051685"(maintenance of ER location)|interpro:IPR026213|mint:P0CAP2|rcsb pdb:6DRD ensembl:ENSG00000163882(gene)|ensembl:ENST00000456318(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032993"(protein-DNA complex)|interpro:IPR005570(RNA polymerase, Rpb8)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:P52434|rcsb pdb:2F3I|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|refseq:NP_006223.2|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|rcsb pdb:7AE3|reactome:R-HSA-1834949|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-427413|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-203927|refseq:NP_001265627.1|refseq:NP_001265628.1|refseq:NP_001265629.1|refseq:NP_001265644.1|refseq:NP_001265643.1|refseq:XP_006713729.1|refseq:XP_006713730.1|refseq:XP_016862125.1|refseq:XP_016862126.1|dip:DIP-27556N - - comment:"author score: 186" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:G0QVxeD0uvJTl0VPn+b3pV6zLe89606 rogid:h7BRWDi8wRbnw/FcFo25bnlVNkE9606 rigid:/44uHYNdWEgFUftM68YkL14pVXg false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06609 uniprotkb:P15924 intact:EBI-297202|uniprotkb:Q6FHX9|ensembl:ENSP00000267868|ensembl:ENSP00000433924|uniprotkb:B0FXP0|uniprotkb:Q9BV60|intact:EBI-1059207|uniprotkb:B2R8T6|uniprotkb:Q6ZNA8 intact:EBI-355041|uniprotkb:O75993|uniprotkb:Q14189|uniprotkb:Q9UHN4|uniprotkb:B2RTT2|uniprotkb:D7RX09|ensembl:ENSP00000369129 psi-mi:rad51_human(display_long)|uniprotkb:RAD51(gene name)|psi-mi:RAD51(display_short)|uniprotkb:RAD51A(gene name synonym)|uniprotkb:RECA(gene name synonym)|uniprotkb:RAD51 homolog A(gene name synonym) psi-mi:desp_human(display_long)|uniprotkb:DSP(gene name)|psi-mi:DSP(display_short)|uniprotkb:250/210 kDa paraneoplastic pemphigus antigen(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483457|imex:IM-26985-427 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020587|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:Q06609|rcsb pdb:1B22|rcsb pdb:1N0W|rcsb pdb:5H1B|rcsb pdb:5H1C|rcsb pdb:5JZC|rcsb pdb:5NP7|rcsb pdb:5NWL|rcsb pdb:7C9A|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-8953750|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0042148"(strand invasion)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051106"(positive regulation of DNA ligation)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0072719"(cellular response to cisplatin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:1904631"(response to glucoside)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR011941(DNA repair protein RAD51)|ensembl:ENSG00000051180(gene)|ensembl:ENST00000267868(transcript)|ensembl:ENST00000532743(transcript)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000800"(lateral element)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016605"(PML body)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0005815"(microtubule organizing center)|refseq:NP_001157742.1|refseq:NP_002866.2|refseq:NP_597994.3|refseq:XP_011520159.1|refseq:XP_011520160.1|refseq:XP_011520161.1|refseq:XP_011520162.1|refseq:XP_011520163.1|refseq:NP_001157741.1|refseq:XP_006720689.1|dip:DIP-462N refseq:NP_001305963.1|refseq:NP_001008844.1|refseq:NP_004406.2|go:"GO:0014704"(intercalated disc)|go:"GO:0005916"(fascia adherens)|go:"GO:0008544"(epidermis development)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042060"(wound healing)|go:"GO:0043588"(skin development)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086083"(cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|ensembl:ENSG00000096696(gene)|ensembl:ENST00000379802(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002934"(desmosome organization)|go:"GO:0003223"(ventricular compact myocardium morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:0150105"(protein localization to cell-cell junction)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR028462|interpro:IPR035915|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:P15924|rcsb pdb:1LM5|rcsb pdb:1LM7|rcsb pdb:3R6N|rcsb pdb:5DZZ|reactome:R-HSA-351906|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371|reactome:R-HSA-9696264|reactome:R-HSA-9696273|dip:DIP-109N - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:B7WPMU7tZuNcA2qjsTR+7i/OwFw9606 rogid:enapEqSoyTSLfPEQUAopkGpdxbo9606 rigid:GWyPdt+8oLSxUVSzNwb6LKXETLY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06609 uniprotkb:Q02413 intact:EBI-297202|uniprotkb:Q6FHX9|ensembl:ENSP00000267868|ensembl:ENSP00000433924|uniprotkb:B0FXP0|uniprotkb:Q9BV60|intact:EBI-1059207|uniprotkb:B2R8T6|uniprotkb:Q6ZNA8 intact:EBI-1045757|intact:EBI-28968615|ensembl:ENSP00000257192|uniprotkb:B7Z845 psi-mi:rad51_human(display_long)|uniprotkb:RAD51(gene name)|psi-mi:RAD51(display_short)|uniprotkb:RAD51A(gene name synonym)|uniprotkb:RECA(gene name synonym)|uniprotkb:RAD51 homolog A(gene name synonym) psi-mi:dsg1_human(display_long)|uniprotkb:CDHF4(gene name synonym)|uniprotkb:Desmosomal glycoprotein 1(gene name synonym)|uniprotkb:Pemphigus foliaceus antigen(gene name synonym)|uniprotkb:DSG1(gene name)|psi-mi:DSG1(display_short)|uniprotkb:Cadherin family member 4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483457|imex:IM-26985-427 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020587|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:Q06609|rcsb pdb:1B22|rcsb pdb:1N0W|rcsb pdb:5H1B|rcsb pdb:5H1C|rcsb pdb:5JZC|rcsb pdb:5NP7|rcsb pdb:5NWL|rcsb pdb:7C9A|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-8953750|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0042148"(strand invasion)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051106"(positive regulation of DNA ligation)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0072719"(cellular response to cisplatin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:1904631"(response to glucoside)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR011941(DNA repair protein RAD51)|ensembl:ENSG00000051180(gene)|ensembl:ENST00000267868(transcript)|ensembl:ENST00000532743(transcript)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000800"(lateral element)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016605"(PML body)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0005815"(microtubule organizing center)|refseq:NP_001157742.1|refseq:NP_002866.2|refseq:NP_597994.3|refseq:XP_011520159.1|refseq:XP_011520160.1|refseq:XP_011520161.1|refseq:XP_011520162.1|refseq:XP_011520163.1|refseq:NP_001157741.1|refseq:XP_006720689.1|dip:DIP-462N ensembl:ENSP00000257192|refseq:NP_001933.2|ensembl:ENSG00000134760(gene)|ensembl:ENST00000257192(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015643"(toxic substance binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0030057"(desmosome)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR009122(Desmosomal cadherin)|interpro:IPR009123(Desmoglein)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|mint:Q02413|reactome:R-HSA-351906|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371|reactome:R-HSA-9696264|reactome:R-HSA-9696270 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:B7WPMU7tZuNcA2qjsTR+7i/OwFw9606 rogid:CiRFIJ9IWOol9bQpLJPxH8JArtE9606 rigid:GWyPdt+8oLSxUVSzNwb6LKXETLY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06609 uniprotkb:P51587 intact:EBI-297202|uniprotkb:Q6FHX9|ensembl:ENSP00000267868|ensembl:ENSP00000433924|uniprotkb:B0FXP0|uniprotkb:Q9BV60|intact:EBI-1059207|uniprotkb:B2R8T6|uniprotkb:Q6ZNA8 intact:EBI-79792|ensembl:ENSP00000369497|ensembl:ENSP00000439902|uniprotkb:Q5TBJ7|uniprotkb:O00183|uniprotkb:O15008|uniprotkb:Q13879 psi-mi:rad51_human(display_long)|uniprotkb:RAD51(gene name)|psi-mi:RAD51(display_short)|uniprotkb:RAD51A(gene name synonym)|uniprotkb:RECA(gene name synonym)|uniprotkb:RAD51 homolog A(gene name synonym) psi-mi:brca2_human(display_long)|uniprotkb:BRCA2(gene name)|psi-mi:BRCA2(display_short)|uniprotkb:FANCD1(gene name synonym)|uniprotkb:FACD(gene name synonym)|uniprotkb:Fanconi anemia group D1 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483457|imex:IM-26985-427 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020587|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:Q06609|rcsb pdb:1B22|rcsb pdb:1N0W|rcsb pdb:5H1B|rcsb pdb:5H1C|rcsb pdb:5JZC|rcsb pdb:5NP7|rcsb pdb:5NWL|rcsb pdb:7C9A|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-8953750|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0042148"(strand invasion)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051106"(positive regulation of DNA ligation)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0072719"(cellular response to cisplatin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:1904631"(response to glucoside)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR011941(DNA repair protein RAD51)|ensembl:ENSG00000051180(gene)|ensembl:ENST00000267868(transcript)|ensembl:ENST00000532743(transcript)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000800"(lateral element)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016605"(PML body)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0005815"(microtubule organizing center)|refseq:NP_001157742.1|refseq:NP_002866.2|refseq:NP_597994.3|refseq:XP_011520159.1|refseq:XP_011520160.1|refseq:XP_011520161.1|refseq:XP_011520162.1|refseq:XP_011520163.1|refseq:NP_001157741.1|refseq:XP_006720689.1|dip:DIP-462N ensembl:ENSG00000139618(gene)|ensembl:ENST00000380152(transcript)|ensembl:ENST00000544455(transcript)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000800"(lateral element)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0002020"(protease binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007420"(brain development)|go:"GO:0007569"(cell aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008585"(female gonad development)|go:"GO:0010165"(response to X-ray)|go:"GO:0010225"(response to UV-C)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010484"(H3 histone acetyltransferase activity)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030141"(secretory granule)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033593"(BRCA2-MAGE-D1 complex)|go:"GO:0033600"(negative regulation of mammary gland epithelial cell proliferation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048478"(replication fork protection)|go:"GO:0051298"(centrosome duplication)|go:"GO:0070200"(establishment of protein localization to telomere)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR002093(BRCA2 repeat)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR015187(BRCA2, oligonucleotide/oligosaccharide-binding 1)|interpro:IPR015188(BRCA2, oligonucleotide/oligosaccharide-binding 3)|interpro:IPR015205(Tower)|interpro:IPR015252(BRCA2, helical)|interpro:IPR015525(Breast cancer type 2 susceptibility protein)|interpro:IPR036315|mint:P51587|rcsb pdb:1N0W|rcsb pdb:3EU7|rcsb pdb:6GY2|go:"GO:0007141"(male meiosis I)|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|rcsb pdb:6HQU|refseq:NP_000050.2|dip:DIP-24214N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:B7WPMU7tZuNcA2qjsTR+7i/OwFw9606 rogid:GvNlXMFXTHiRgOGT5EBlQUVh/+k9606 rigid:GWyPdt+8oLSxUVSzNwb6LKXETLY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06609 uniprotkb:P16403 intact:EBI-297202|uniprotkb:Q6FHX9|ensembl:ENSP00000267868|ensembl:ENSP00000433924|uniprotkb:B0FXP0|uniprotkb:Q9BV60|intact:EBI-1059207|uniprotkb:B2R8T6|uniprotkb:Q6ZNA8 intact:EBI-358372|ensembl:ENSP00000339566|uniprotkb:A8K4I2 psi-mi:rad51_human(display_long)|uniprotkb:RAD51(gene name)|psi-mi:RAD51(display_short)|uniprotkb:RAD51A(gene name synonym)|uniprotkb:RECA(gene name synonym)|uniprotkb:RAD51 homolog A(gene name synonym) psi-mi:h12_human(display_long)|uniprotkb:H1-2(gene name)|psi-mi:H1-2(display_short)|uniprotkb:H1F2(gene name synonym)|uniprotkb:HIST1H1C(gene name synonym)|uniprotkb:Histone H1c(gene name synonym)|uniprotkb:Histone H1d(gene name synonym)|uniprotkb:Histone H1s-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483457|imex:IM-26985-427 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020587|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:Q06609|rcsb pdb:1B22|rcsb pdb:1N0W|rcsb pdb:5H1B|rcsb pdb:5H1C|rcsb pdb:5JZC|rcsb pdb:5NP7|rcsb pdb:5NWL|rcsb pdb:7C9A|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-8953750|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0042148"(strand invasion)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051106"(positive regulation of DNA ligation)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0072719"(cellular response to cisplatin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:1904631"(response to glucoside)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR011941(DNA repair protein RAD51)|ensembl:ENSG00000051180(gene)|ensembl:ENST00000267868(transcript)|ensembl:ENST00000532743(transcript)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000800"(lateral element)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016605"(PML body)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0005815"(microtubule organizing center)|refseq:NP_001157742.1|refseq:NP_002866.2|refseq:NP_597994.3|refseq:XP_011520159.1|refseq:XP_011520160.1|refseq:XP_011520161.1|refseq:XP_011520162.1|refseq:XP_011520163.1|refseq:NP_001157741.1|refseq:XP_006720689.1|dip:DIP-462N refseq:NP_005310.1|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P16403|reactome:R-HSA-140342|reactome:R-HSA-2559584|ensembl:ENSG00000187837(gene)|ensembl:ENST00000343677(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|dip:DIP-36359N - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:B7WPMU7tZuNcA2qjsTR+7i/OwFw9606 rogid:eRT5bTyBJUg6nRANMRYZekT4N+g9606 rigid:GWyPdt+8oLSxUVSzNwb6LKXETLY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06609 uniprotkb:P07477 intact:EBI-297202|uniprotkb:Q6FHX9|ensembl:ENSP00000267868|ensembl:ENSP00000433924|uniprotkb:B0FXP0|uniprotkb:Q9BV60|intact:EBI-1059207|uniprotkb:B2R8T6|uniprotkb:Q6ZNA8 intact:EBI-1222902|uniprotkb:A6NJ71|uniprotkb:Q92955|uniprotkb:Q9HAN4|uniprotkb:Q9HAN5|uniprotkb:Q9HAN6|uniprotkb:Q9HAN7|intact:EBI-1760472|intact:EBI-1965533|uniprotkb:A1A509|uniprotkb:Q5NV57|uniprotkb:Q7M4N3|uniprotkb:Q7M4N4|uniprotkb:B2R5I5|ensembl:ENSP00000308720|ensembl:ENSP00000479217 psi-mi:rad51_human(display_long)|uniprotkb:RAD51(gene name)|psi-mi:RAD51(display_short)|uniprotkb:RAD51A(gene name synonym)|uniprotkb:RECA(gene name synonym)|uniprotkb:RAD51 homolog A(gene name synonym) psi-mi:try1_human(display_long)|uniprotkb:PRSS1(gene name)|psi-mi:PRSS1(display_short)|uniprotkb:TRP1(gene name synonym)|uniprotkb:TRY1(gene name synonym)|uniprotkb:TRYP1(gene name synonym)|uniprotkb:Trypsin I(gene name synonym)|uniprotkb:Cationic trypsinogen(gene name synonym)|uniprotkb:Serine protease 1(gene name synonym)|uniprotkb:Beta-trypsin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483457|imex:IM-26985-427 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020587|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:Q06609|rcsb pdb:1B22|rcsb pdb:1N0W|rcsb pdb:5H1B|rcsb pdb:5H1C|rcsb pdb:5JZC|rcsb pdb:5NP7|rcsb pdb:5NWL|rcsb pdb:7C9A|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-8953750|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0042148"(strand invasion)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051106"(positive regulation of DNA ligation)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0072719"(cellular response to cisplatin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:1904631"(response to glucoside)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR011941(DNA repair protein RAD51)|ensembl:ENSG00000051180(gene)|ensembl:ENST00000267868(transcript)|ensembl:ENST00000532743(transcript)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000800"(lateral element)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016605"(PML body)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0005815"(microtubule organizing center)|refseq:NP_001157742.1|refseq:NP_002866.2|refseq:NP_597994.3|refseq:XP_011520159.1|refseq:XP_011520160.1|refseq:XP_011520161.1|refseq:XP_011520162.1|refseq:XP_011520163.1|refseq:NP_001157741.1|refseq:XP_006720689.1|dip:DIP-462N refseq:NP_002760.1|ensembl:ENSG00000204983(gene)|ensembl:ENSG00000274247(gene)|ensembl:ENST00000311737(transcript)|ensembl:ENST00000616256(transcript)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0007586"(digestion)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0072562"(blood microparticle)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR033116|interpro:IPR043504|mint:P07477|rcsb pdb:1FXY|rcsb pdb:1TRN|rcsb pdb:2RA3|rcsb pdb:4WWY|rcsb pdb:4WXV|reactome:R-HSA-1592389|reactome:R-HSA-196741 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:B7WPMU7tZuNcA2qjsTR+7i/OwFw9606 rogid:2elS/qMYj0sflxilyWfk3KPtGmo9606 rigid:GWyPdt+8oLSxUVSzNwb6LKXETLY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06609 uniprotkb:Q96P63 intact:EBI-297202|uniprotkb:Q6FHX9|ensembl:ENSP00000267868|ensembl:ENSP00000433924|uniprotkb:B0FXP0|uniprotkb:Q9BV60|intact:EBI-1059207|uniprotkb:B2R8T6|uniprotkb:Q6ZNA8 intact:EBI-2553395|uniprotkb:Q3SYB4|ensembl:ENSP00000269491 psi-mi:rad51_human(display_long)|uniprotkb:RAD51(gene name)|psi-mi:RAD51(display_short)|uniprotkb:RAD51A(gene name synonym)|uniprotkb:RECA(gene name synonym)|uniprotkb:RAD51 homolog A(gene name synonym) psi-mi:spb12_human(display_long)|uniprotkb:SERPINB12(gene name)|psi-mi:SERPINB12(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483457|imex:IM-26985-427 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020587|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:Q06609|rcsb pdb:1B22|rcsb pdb:1N0W|rcsb pdb:5H1B|rcsb pdb:5H1C|rcsb pdb:5JZC|rcsb pdb:5NP7|rcsb pdb:5NWL|rcsb pdb:7C9A|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-8953750|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0042148"(strand invasion)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051106"(positive regulation of DNA ligation)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0072719"(cellular response to cisplatin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:1904631"(response to glucoside)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR011941(DNA repair protein RAD51)|ensembl:ENSG00000051180(gene)|ensembl:ENST00000267868(transcript)|ensembl:ENST00000532743(transcript)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000800"(lateral element)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016605"(PML body)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0005815"(microtubule organizing center)|refseq:NP_001157742.1|refseq:NP_002866.2|refseq:NP_597994.3|refseq:XP_011520159.1|refseq:XP_011520160.1|refseq:XP_011520161.1|refseq:XP_011520162.1|refseq:XP_011520163.1|refseq:NP_001157741.1|refseq:XP_006720689.1|dip:DIP-462N refseq:NP_001294857.1|refseq:XP_011524550.1|refseq:XP_011524551.1|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:Q96P63|reactome:R-HSA-6798695|refseq:NP_536722.1|ensembl:ENSG00000166634(gene)|ensembl:ENST00000269491(transcript)|refseq:XP_016881556.1 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:B7WPMU7tZuNcA2qjsTR+7i/OwFw9606 rogid:rjDNYwceRueAXnaDN3nJNMqwRxM9606 rigid:GWyPdt+8oLSxUVSzNwb6LKXETLY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06609 uniprotkb:P81605 intact:EBI-297202|uniprotkb:Q6FHX9|ensembl:ENSP00000267868|ensembl:ENSP00000433924|uniprotkb:B0FXP0|uniprotkb:Q9BV60|intact:EBI-1059207|uniprotkb:B2R8T6|uniprotkb:Q6ZNA8 intact:EBI-395625|uniprotkb:P58461|uniprotkb:A5JHP2|uniprotkb:A5JHP3|uniprotkb:Q53YJ2|ensembl:ENSP00000293371 psi-mi:rad51_human(display_long)|uniprotkb:RAD51(gene name)|psi-mi:RAD51(display_short)|uniprotkb:RAD51A(gene name synonym)|uniprotkb:RECA(gene name synonym)|uniprotkb:RAD51 homolog A(gene name synonym) psi-mi:dcd_human(display_long)|uniprotkb:AIDD(gene name synonym)|uniprotkb:DSEP(gene name synonym)|uniprotkb:Preproteolysin(gene name synonym)|uniprotkb:DCD(gene name)|psi-mi:DCD(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483457|imex:IM-26985-427 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020587|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:Q06609|rcsb pdb:1B22|rcsb pdb:1N0W|rcsb pdb:5H1B|rcsb pdb:5H1C|rcsb pdb:5JZC|rcsb pdb:5NP7|rcsb pdb:5NWL|rcsb pdb:7C9A|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-8953750|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0042148"(strand invasion)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051106"(positive regulation of DNA ligation)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0072719"(cellular response to cisplatin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:1904631"(response to glucoside)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR011941(DNA repair protein RAD51)|ensembl:ENSG00000051180(gene)|ensembl:ENST00000267868(transcript)|ensembl:ENST00000532743(transcript)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000800"(lateral element)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016605"(PML body)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0005815"(microtubule organizing center)|refseq:NP_001157742.1|refseq:NP_002866.2|refseq:NP_597994.3|refseq:XP_011520159.1|refseq:XP_011520160.1|refseq:XP_011520161.1|refseq:XP_011520162.1|refseq:XP_011520163.1|refseq:NP_001157741.1|refseq:XP_006720689.1|dip:DIP-462N refseq:NP_444513.1|refseq:NP_001287783.1|ensembl:ENSG00000161634(gene)|ensembl:ENST00000293371(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008233"(peptidase activity)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR028130|interpro:IPR043557|mint:P81605|rcsb pdb:2KSG|rcsb pdb:2NDK|rcsb pdb:2YMK|rcsb pdb:6SHK|reactome:R-HSA-6803157 - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:B7WPMU7tZuNcA2qjsTR+7i/OwFw9606 rogid:M8PkKVWx98nhtd79ods05mqw8Ls9606 rigid:GWyPdt+8oLSxUVSzNwb6LKXETLY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06609 uniprotkb:Q01469 intact:EBI-297202|uniprotkb:Q6FHX9|ensembl:ENSP00000267868|ensembl:ENSP00000433924|uniprotkb:B0FXP0|uniprotkb:Q9BV60|intact:EBI-1059207|uniprotkb:B2R8T6|uniprotkb:Q6ZNA8 intact:EBI-1054073|uniprotkb:B2R4K0|ensembl:ENSP00000297258 psi-mi:rad51_human(display_long)|uniprotkb:RAD51(gene name)|psi-mi:RAD51(display_short)|uniprotkb:RAD51A(gene name synonym)|uniprotkb:RECA(gene name synonym)|uniprotkb:RAD51 homolog A(gene name synonym) psi-mi:fabp5_human(display_long)|uniprotkb:Epidermal-type fatty acid-binding protein(gene name synonym)|uniprotkb:Psoriasis-associated fatty acid-binding protein homolog(gene name synonym)|uniprotkb:FABP5(gene name)|psi-mi:FABP5(display_short)|uniprotkb:Fatty acid-binding protein, epidermal(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483457|imex:IM-26985-427 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020587|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:Q06609|rcsb pdb:1B22|rcsb pdb:1N0W|rcsb pdb:5H1B|rcsb pdb:5H1C|rcsb pdb:5JZC|rcsb pdb:5NP7|rcsb pdb:5NWL|rcsb pdb:7C9A|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-8953750|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0042148"(strand invasion)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051106"(positive regulation of DNA ligation)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0072719"(cellular response to cisplatin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:1904631"(response to glucoside)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR011941(DNA repair protein RAD51)|ensembl:ENSG00000051180(gene)|ensembl:ENST00000267868(transcript)|ensembl:ENST00000532743(transcript)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000800"(lateral element)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016605"(PML body)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0005815"(microtubule organizing center)|refseq:NP_001157742.1|refseq:NP_002866.2|refseq:NP_597994.3|refseq:XP_011520159.1|refseq:XP_011520160.1|refseq:XP_011520161.1|refseq:XP_011520162.1|refseq:XP_011520163.1|refseq:NP_001157741.1|refseq:XP_006720689.1|dip:DIP-462N refseq:NP_001435.1|ensembl:ENSG00000164687(gene)|ensembl:ENST00000297258(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0008289"(lipid binding)|go:"GO:0008544"(epidermis development)|go:"GO:0010829"(negative regulation of glucose transmembrane transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031392"(regulation of prostaglandin biosynthetic process)|go:"GO:0035360"(positive regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099178"(regulation of retrograde trans-synaptic signaling by endocanabinoid)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990379"(lipid transport across blood-brain barrier)|interpro:IPR000463(Cytosolic fatty-acid binding)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR012674(Calycin)|interpro:IPR031259|mint:Q01469|rcsb pdb:1B56|rcsb pdb:1JJJ|rcsb pdb:4AZM|rcsb pdb:4AZR|rcsb pdb:4LKP|rcsb pdb:4LKT|rcsb pdb:5HZ5|rcsb pdb:5UR9|reactome:R-HSA-163560|reactome:R-HSA-5362517|reactome:R-HSA-6798695 - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:B7WPMU7tZuNcA2qjsTR+7i/OwFw9606 rogid:vxp81/mezHcm5oo27QOmAM8Y5dI9606 rigid:GWyPdt+8oLSxUVSzNwb6LKXETLY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06609 uniprotkb:P68363 intact:EBI-297202|uniprotkb:Q6FHX9|ensembl:ENSP00000267868|ensembl:ENSP00000433924|uniprotkb:B0FXP0|uniprotkb:Q9BV60|intact:EBI-1059207|uniprotkb:B2R8T6|uniprotkb:Q6ZNA8 intact:EBI-487083|intact:EBI-1384226|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:Q27I68|ensembl:ENSP00000336799|uniprotkb:Q8WU19 psi-mi:rad51_human(display_long)|uniprotkb:RAD51(gene name)|psi-mi:RAD51(display_short)|uniprotkb:RAD51A(gene name synonym)|uniprotkb:RECA(gene name synonym)|uniprotkb:RAD51 homolog A(gene name synonym) psi-mi:tba1b_human(display_long)|uniprotkb:TUBA1B(gene name)|psi-mi:TUBA1B(display_short)|uniprotkb:Tubulin alpha-ubiquitous chain(gene name synonym)|uniprotkb:Alpha-tubulin ubiquitous(gene name synonym)|uniprotkb:Tubulin K-alpha-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483457|imex:IM-26985-427 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020587|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:Q06609|rcsb pdb:1B22|rcsb pdb:1N0W|rcsb pdb:5H1B|rcsb pdb:5H1C|rcsb pdb:5JZC|rcsb pdb:5NP7|rcsb pdb:5NWL|rcsb pdb:7C9A|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-8953750|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0042148"(strand invasion)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051106"(positive regulation of DNA ligation)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0072719"(cellular response to cisplatin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:1904631"(response to glucoside)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR011941(DNA repair protein RAD51)|ensembl:ENSG00000051180(gene)|ensembl:ENST00000267868(transcript)|ensembl:ENST00000532743(transcript)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000800"(lateral element)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016605"(PML body)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0005815"(microtubule organizing center)|refseq:NP_001157742.1|refseq:NP_002866.2|refseq:NP_597994.3|refseq:XP_011520159.1|refseq:XP_011520160.1|refseq:XP_011520161.1|refseq:XP_011520162.1|refseq:XP_011520163.1|refseq:NP_001157741.1|refseq:XP_006720689.1|dip:DIP-462N refseq:NP_006073.2|ensembl:ENSG00000123416(gene)|ensembl:ENST00000336023(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-983189|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|go:"GO:0045121"(membrane raft)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68363|rcsb pdb:2E4H|rcsb pdb:5IJ0|rcsb pdb:5IJ9|rcsb pdb:5N5N|rcsb pdb:6E7B|rcsb pdb:6E7C|rcsb pdb:6I2I|go:"GO:0051301"(cell division)|rcsb pdb:6J4V|rcsb pdb:6J8O|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|rcsb pdb:6S8L|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9013407|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-2132295|reactome:R-HSA-9668328 - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:B7WPMU7tZuNcA2qjsTR+7i/OwFw9606 rogid:D4YpuLCXl/S+53qV7P7sF81aARY9606 rigid:GWyPdt+8oLSxUVSzNwb6LKXETLY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06609 uniprotkb:P62899 intact:EBI-297202|uniprotkb:Q6FHX9|ensembl:ENSP00000267868|ensembl:ENSP00000433924|uniprotkb:B0FXP0|uniprotkb:Q9BV60|intact:EBI-1059207|uniprotkb:B2R8T6|uniprotkb:Q6ZNA8 intact:EBI-1053664|intact:EBI-3867511|uniprotkb:B7Z4K2|uniprotkb:P12947|uniprotkb:Q53SQ5|uniprotkb:Q6LBJ6|uniprotkb:D3DVJ4|uniprotkb:Q6IRZ0|ensembl:ENSP00000264258|ensembl:ENSP00000386681 psi-mi:rad51_human(display_long)|uniprotkb:RAD51(gene name)|psi-mi:RAD51(display_short)|uniprotkb:RAD51A(gene name synonym)|uniprotkb:RECA(gene name synonym)|uniprotkb:RAD51 homolog A(gene name synonym) psi-mi:rl31_human(display_long)|uniprotkb:RPL31(gene name)|psi-mi:RPL31(display_short)|uniprotkb:Large ribosomal subunit protein eL31(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483457|imex:IM-26985-427 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020587|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:Q06609|rcsb pdb:1B22|rcsb pdb:1N0W|rcsb pdb:5H1B|rcsb pdb:5H1C|rcsb pdb:5JZC|rcsb pdb:5NP7|rcsb pdb:5NWL|rcsb pdb:7C9A|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-8953750|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0042148"(strand invasion)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051106"(positive regulation of DNA ligation)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0072719"(cellular response to cisplatin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:1904631"(response to glucoside)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR011941(DNA repair protein RAD51)|ensembl:ENSG00000051180(gene)|ensembl:ENST00000267868(transcript)|ensembl:ENST00000532743(transcript)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000800"(lateral element)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016605"(PML body)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0005815"(microtubule organizing center)|refseq:NP_001157742.1|refseq:NP_002866.2|refseq:NP_597994.3|refseq:XP_011520159.1|refseq:XP_011520160.1|refseq:XP_011520161.1|refseq:XP_011520162.1|refseq:XP_011520163.1|refseq:NP_001157741.1|refseq:XP_006720689.1|dip:DIP-462N refseq:NP_000984.1|refseq:NP_001092047.1|refseq:NP_001093163.1|ensembl:ENSG00000071082(gene)|ensembl:ENST00000264258(transcript)|ensembl:ENST00000409733(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000054(Ribosomal protein L31e)|interpro:IPR020052|interpro:IPR023621|mint:P62899|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:B7WPMU7tZuNcA2qjsTR+7i/OwFw9606 rogid:77LFR7/2somk6blVogZf1XFdJLk9606 rigid:GWyPdt+8oLSxUVSzNwb6LKXETLY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06609 uniprotkb:P62701 intact:EBI-297202|uniprotkb:Q6FHX9|ensembl:ENSP00000267868|ensembl:ENSP00000433924|uniprotkb:B0FXP0|uniprotkb:Q9BV60|intact:EBI-1059207|uniprotkb:B2R8T6|uniprotkb:Q6ZNA8 intact:EBI-354303|uniprotkb:P12631|uniprotkb:P12750|uniprotkb:P27576|uniprotkb:Q14727|uniprotkb:P55831|uniprotkb:Q6IPY4|ensembl:ENSP00000362744 psi-mi:rad51_human(display_long)|uniprotkb:RAD51(gene name)|psi-mi:RAD51(display_short)|uniprotkb:RAD51A(gene name synonym)|uniprotkb:RECA(gene name synonym)|uniprotkb:RAD51 homolog A(gene name synonym) psi-mi:rs4x_human(display_long)|uniprotkb:RPS4X(gene name)|psi-mi:RPS4X(display_short)|uniprotkb:CCG2(gene name synonym)|uniprotkb:RPS4(gene name synonym)|uniprotkb:SCAR(gene name synonym)|uniprotkb:Single copy abundant mRNA protein(gene name synonym)|uniprotkb:SCR10(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483457|imex:IM-26985-427 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020587|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:Q06609|rcsb pdb:1B22|rcsb pdb:1N0W|rcsb pdb:5H1B|rcsb pdb:5H1C|rcsb pdb:5JZC|rcsb pdb:5NP7|rcsb pdb:5NWL|rcsb pdb:7C9A|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-8953750|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0042148"(strand invasion)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051106"(positive regulation of DNA ligation)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0072719"(cellular response to cisplatin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:1904631"(response to glucoside)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR011941(DNA repair protein RAD51)|ensembl:ENSG00000051180(gene)|ensembl:ENST00000267868(transcript)|ensembl:ENST00000532743(transcript)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000800"(lateral element)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016605"(PML body)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0005815"(microtubule organizing center)|refseq:NP_001157742.1|refseq:NP_002866.2|refseq:NP_597994.3|refseq:XP_011520159.1|refseq:XP_011520160.1|refseq:XP_011520161.1|refseq:XP_011520162.1|refseq:XP_011520163.1|refseq:NP_001157741.1|refseq:XP_006720689.1|dip:DIP-462N refseq:NP_000998.1|rcsb pdb:6OLI|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000198034(gene)|ensembl:ENST00000316084(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045202"(synapse)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000876(Ribosomal protein S4e)|interpro:IPR002942(RNA-binding S4)|interpro:IPR005824(KOW)|interpro:IPR013843(Ribosomal protein S4e, N-terminal)|interpro:IPR013845(Ribosomal protein S4e, central)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR018199|interpro:IPR032277|interpro:IPR036986|interpro:IPR038237|interpro:IPR041982|mint:P62701|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|go:"GO:0045727"(positive regulation of translation)|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF - - comment:"author score: 27" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:B7WPMU7tZuNcA2qjsTR+7i/OwFw9606 rogid:2ZuLXqBSDkK0CtN3mnIDoFAR8yI9606 rigid:GWyPdt+8oLSxUVSzNwb6LKXETLY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06609 uniprotkb:P39019 intact:EBI-297202|uniprotkb:Q6FHX9|ensembl:ENSP00000267868|ensembl:ENSP00000433924|uniprotkb:B0FXP0|uniprotkb:Q9BV60|intact:EBI-1059207|uniprotkb:B2R8T6|uniprotkb:Q6ZNA8 intact:EBI-354451|ensembl:ENSP00000469228|ensembl:ENSP00000470004|ensembl:ENSP00000470972 psi-mi:rad51_human(display_long)|uniprotkb:RAD51(gene name)|psi-mi:RAD51(display_short)|uniprotkb:RAD51A(gene name synonym)|uniprotkb:RECA(gene name synonym)|uniprotkb:RAD51 homolog A(gene name synonym) psi-mi:rs19_human(display_long)|uniprotkb:RPS19(gene name)|psi-mi:RPS19(display_short)|uniprotkb:Small ribosomal subunit protein eS19(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483457|imex:IM-26985-427 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020587|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:Q06609|rcsb pdb:1B22|rcsb pdb:1N0W|rcsb pdb:5H1B|rcsb pdb:5H1C|rcsb pdb:5JZC|rcsb pdb:5NP7|rcsb pdb:5NWL|rcsb pdb:7C9A|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-8953750|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0042148"(strand invasion)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051106"(positive regulation of DNA ligation)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0072719"(cellular response to cisplatin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:1904631"(response to glucoside)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR011941(DNA repair protein RAD51)|ensembl:ENSG00000051180(gene)|ensembl:ENST00000267868(transcript)|ensembl:ENST00000532743(transcript)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000800"(lateral element)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016605"(PML body)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0005815"(microtubule organizing center)|refseq:NP_001157742.1|refseq:NP_002866.2|refseq:NP_597994.3|refseq:XP_011520159.1|refseq:XP_011520160.1|refseq:XP_011520161.1|refseq:XP_011520162.1|refseq:XP_011520163.1|refseq:NP_001157741.1|refseq:XP_006720689.1|dip:DIP-462N refseq:NP_001013.1|ensembl:ENSG00000105372(gene)|ensembl:ENST00000593863(transcript)|ensembl:ENST00000598742(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003723"(RNA binding)|ensembl:ENST00000600467(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0007000"(nucleolus organization)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0060265"(positive regulation of respiratory burst involved in inflammatory response)|go:"GO:0060266"(negative regulation of respiratory burst involved in inflammatory response)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001266(Ribosomal protein S19e)|interpro:IPR018277|interpro:IPR036388|interpro:IPR036390|mint:P39019|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001308412.1|refseq:NP_001308413.1 - - comment:"author score: 46" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:B7WPMU7tZuNcA2qjsTR+7i/OwFw9606 rogid:3YqdJJJG+2nqoBf3PLu1fs7pVkY9606 rigid:GWyPdt+8oLSxUVSzNwb6LKXETLY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06609 uniprotkb:P01040 intact:EBI-297202|uniprotkb:Q6FHX9|ensembl:ENSP00000267868|ensembl:ENSP00000433924|uniprotkb:B0FXP0|uniprotkb:Q9BV60|intact:EBI-1059207|uniprotkb:B2R8T6|uniprotkb:Q6ZNA8 intact:EBI-724303|ensembl:ENSP00000264474|uniprotkb:Q6IB90 psi-mi:rad51_human(display_long)|uniprotkb:RAD51(gene name)|psi-mi:RAD51(display_short)|uniprotkb:RAD51A(gene name synonym)|uniprotkb:RECA(gene name synonym)|uniprotkb:RAD51 homolog A(gene name synonym) psi-mi:cyta_human(display_long)|uniprotkb:Cystatin-AS(gene name synonym)|uniprotkb:Stefin-A(gene name synonym)|uniprotkb:CSTA(gene name)|psi-mi:CSTA(display_short)|uniprotkb:STF1(gene name synonym)|uniprotkb:STFA(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483457|imex:IM-26985-427 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) interpro:IPR013632(Rad51, C-terminal)|interpro:IPR016467(DNA repair and recombination, RecA-like)|interpro:IPR020587|interpro:IPR020588|interpro:IPR027417|interpro:IPR033925|mint:Q06609|rcsb pdb:1B22|rcsb pdb:1N0W|rcsb pdb:5H1B|rcsb pdb:5H1C|rcsb pdb:5JZC|rcsb pdb:5NP7|rcsb pdb:5NWL|rcsb pdb:7C9A|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693554|reactome:R-HSA-5693568|reactome:R-HSA-5693579|reactome:R-HSA-5693616|reactome:R-HSA-912446|reactome:R-HSA-8953750|go:"GO:0035861"(site of double-strand break)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0042148"(strand invasion)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051106"(positive regulation of DNA ligation)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070192"(chromosome organization involved in meiotic cell cycle)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0072719"(cellular response to cisplatin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:1904631"(response to glucoside)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|go:"GO:1990426"(mitotic recombination-dependent replication fork processing)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010995(DNA repair Rad51/transcription factor NusA, alpha-helical)|interpro:IPR011941(DNA repair protein RAD51)|ensembl:ENSG00000051180(gene)|ensembl:ENST00000267868(transcript)|ensembl:ENST00000532743(transcript)|go:"GO:0000150"(DNA strand exchange activity)|go:"GO:0000722"(telomere maintenance via recombination)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000730"(DNA recombinase assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000800"(lateral element)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006312"(mitotic recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0009636"(response to toxic substance)|go:"GO:0010165"(response to X-ray)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0010833"(telomere maintenance via telomere lengthening)|go:"GO:0016605"(PML body)|go:"GO:0017116"(single-stranded DNA helicase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031297"(replication fork processing)|go:"GO:0005815"(microtubule organizing center)|refseq:NP_001157742.1|refseq:NP_002866.2|refseq:NP_597994.3|refseq:XP_011520159.1|refseq:XP_011520160.1|refseq:XP_011520161.1|refseq:XP_011520162.1|refseq:XP_011520163.1|refseq:NP_001157741.1|refseq:XP_006720689.1|dip:DIP-462N refseq:NP_005204.1|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR001713(Proteinase inhibitor I25A, stefin A)|mint:P01040|rcsb pdb:1CYU|rcsb pdb:1CYV|rcsb pdb:1DVC|rcsb pdb:1DVD|rcsb pdb:1GD3|rcsb pdb:1GD4|rcsb pdb:1N9J|rcsb pdb:1NB3|rcsb pdb:1NB5|rcsb pdb:3K9M|rcsb pdb:3KFQ|interpro:IPR018073|rcsb pdb:3KSE|reactome:R-HSA-6809371|ensembl:ENSG00000121552(gene)|ensembl:ENST00000264474(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002020"(protease binding)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0045861"(negative regulation of proteolysis) - - comment:"author score: 50" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:B7WPMU7tZuNcA2qjsTR+7i/OwFw9606 rogid:SzbpyWUHlOtItIvffzuwhcqFsDI9606 rigid:GWyPdt+8oLSxUVSzNwb6LKXETLY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q8IXM2 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-4280811|uniprotkb:B4DIV3|ensembl:ENSP00000411851|uniprotkb:E9PB29|uniprotkb:C9J4G0 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:bap18_human(display_long)|uniprotkb:BAP18(gene name)|psi-mi:BAP18(display_short)|uniprotkb:C17orf49(gene name synonym)|uniprotkb:BPTF-associated protein of 18 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483502|imex:IM-26985-201 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N refseq:NP_777553.1|ensembl:ENSG00000258315(gene)|ensembl:ENST00000439424(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0016589"(NURF complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR037931|mint:Q8IXM2|refseq:NP_001136271.1|refseq:NP_001136270.1|dip:DIP-60552N - - comment:"author score: 47" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:JewuVFQI/LJRK5UZ0PeCsAhHGIE9606 rigid:tLA/YunZf+3g+O4giAYnP4Ty0nA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q9UGU5 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-7261162|uniprotkb:O75673|intact:MINT-6783307|uniprotkb:Q9UMT5|uniprotkb:O75672|ensembl:ENSP00000216106 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:hmgx4_human(display_long)|uniprotkb:HMGBCG(gene name synonym)|uniprotkb:Protein HMGBCG(gene name synonym)|uniprotkb:HMGXB4(gene name)|psi-mi:HMGXB4(display_short)|uniprotkb:HMG2L1(gene name synonym)|uniprotkb:HMG box-containing protein 4(gene name synonym)|uniprotkb:High mobility group protein 2-like 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483502|imex:IM-26985-201 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N refseq:NP_001003681.1|ensembl:ENSG00000100281(gene)|ensembl:ENST00000216106(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016589"(NURF complex)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR025228|interpro:IPR036910|interpro:IPR042477|mint:Q9UGU5|refseq:XP_006724165.1|dip:DIP-60550N - - comment:mint|comment:homomint|comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:RLeajOlLuVCUoPeRolss9x3wAQY9606 rigid:tLA/YunZf+3g+O4giAYnP4Ty0nA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q96QT6 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-2803760|uniprotkb:Q9BV34|uniprotkb:Q9P205|uniprotkb:Q6ZML2|uniprotkb:Q0VAI5|uniprotkb:Q9H7U9|ensembl:ENSP00000329933|uniprotkb:Q2TAK2 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:phf12_human(display_long)|uniprotkb:KIAA1523(gene name synonym)|uniprotkb:PHD factor 1(gene name synonym)|uniprotkb:PHF12(gene name)|psi-mi:PHF12(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483502|imex:IM-26985-201 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N refseq:NP_001028733.1|refseq:NP_065940.1|ensembl:ENSG00000109118(gene)|ensembl:ENST00000332830(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016580"(Sin3 complex)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070822"(Sin3-type complex)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR031966|interpro:IPR038098|interpro:IPR042163|mint:Q96QT6|rcsb pdb:2L9S|rcsb pdb:2LKM|refseq:NP_001277060.1|dip:DIP-59632N - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:PSctZ9CGOcztlg6VdcB1jkIOhjo9606 rigid:tLA/YunZf+3g+O4giAYnP4Ty0nA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:O14929 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-2339359|uniprotkb:Q53SU4|uniprotkb:Q53QF0|uniprotkb:Q49A44|uniprotkb:Q6P594|uniprotkb:Q8WWB9|ensembl:ENSP00000264108 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:hat1_human(display_long)|uniprotkb:HAT1(gene name)|psi-mi:HAT1(display_short)|uniprotkb:KAT1(gene name synonym)|uniprotkb:Histone acetyltransferase 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483502|imex:IM-26985-201 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N refseq:NP_003633.1|dip:DIP-52811N|ensembl:ENSG00000128708(gene)|ensembl:ENST00000264108(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006323"(DNA packaging)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006348"|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0007584"(response to nutrient)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR013523(Histone acetyltransferase HAT1, C-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017380(Histone acetyltransferase type B, catalytic subunit)|interpro:IPR019467|interpro:IPR037113|mint:O14929|rcsb pdb:2P0W|rcsb pdb:6VO5|reactome:R-HSA-3214847 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:80KgRaid3NeRfAUdTHMQ/r0VuGo9606 rigid:tLA/YunZf+3g+O4giAYnP4Ty0nA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:P28370 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-2822460|uniprotkb:Q5JV41|uniprotkb:Q5JV42|ensembl:ENSP00000360163 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:smca1_human(display_long)|uniprotkb:SMARCA1(gene name)|psi-mi:SMARCA1(display_short)|uniprotkb:SNF2L(gene name synonym)|uniprotkb:SNF2L1(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA1(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit SNF2L(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483502|imex:IM-26985-201 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N refseq:NP_003060.2|refseq:NP_001269804.1|refseq:XP_006724845.1|refseq:XP_016885239.1|refseq:XP_005262518.1|dip:DIP-57685N|ensembl:ENSG00000102038(gene)|ensembl:ENST00000371122(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007420"(brain development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016589"(NURF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030182"(neuron differentiation)|go:"GO:0031491"(nucleosome binding)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070615"|go:"GO:0090537"(CERF complex)|interpro:IPR000330(SNF2-related)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR009057(Homeodomain-like)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR015194(Nucleosome remodelling ATPase ISWI, HAND)|interpro:IPR015195(SLIDE)|interpro:IPR017884|interpro:IPR020838|interpro:IPR027417|interpro:IPR036306|interpro:IPR038718|interpro:IPR044755|mint:P28370 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:BBDJMLUdqadz6iXLKjLJto+XF5s9606 rigid:tLA/YunZf+3g+O4giAYnP4Ty0nA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q52LA3 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-1389456|ensembl:ENSP00000501511 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:lin52_human(display_long)|uniprotkb:LIN52(gene name)|psi-mi:LIN52(display_short)|uniprotkb:C14orf46(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483502|imex:IM-26985-201 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N refseq:NP_001019845.1|ensembl:ENST00000674221(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0070176"(DRM complex)|interpro:IPR018737|mint:Q52LA3|rcsb pdb:4YOO|rcsb pdb:6C48|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|ensembl:ENSG00000205659(gene) - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:PYctE1wLvOx8wZn+fJU8nDk1v0w9606 rigid:tLA/YunZf+3g+O4giAYnP4Ty0nA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q149N8 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-714105|uniprotkb:Q149N9|uniprotkb:Q5VV79|uniprotkb:Q68DS5|uniprotkb:Q7Z5J5|uniprotkb:Q8IVE8|uniprotkb:Q8IWQ9|uniprotkb:Q8N1S8|uniprotkb:Q8NBR7|ensembl:ENSP00000275233|ensembl:ENSP00000356475 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:shprh_human(display_long)|uniprotkb:SNF2, histone-linker, PHD and RING finger domain-containing helicase(gene name synonym)|uniprotkb:SHPRH(gene name)|psi-mi:SHPRH(display_short)|uniprotkb:KIAA2023(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SHPRH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483502|imex:IM-26985-201 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N refseq:XP_006715504.1|ensembl:ENSG00000146414(gene)|ensembl:ENST00000275233(transcript)|ensembl:ENST00000367505(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016787"(hydrolase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|go:"GO:0031625"(ubiquitin protein ligase binding)|interpro:IPR005818(Histone H1/H5)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR017907|interpro:IPR019786|interpro:IPR027417|interpro:IPR036388|interpro:IPR036390|interpro:IPR038718|mint:Q149N8|rcsb pdb:2M85|rcsb pdb:4QN1|reactome:R-HSA-8866654|refseq:NP_001036148.2|refseq:NP_775105.1|dip:DIP-46277N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:WqU1cBAHV1M5PmgDpqRh11/rNmA9606 rigid:tLA/YunZf+3g+O4giAYnP4Ty0nA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q4LE39 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-2680990|uniprotkb:Q86UX1|uniprotkb:Q5T2C5|uniprotkb:Q9NZB6|uniprotkb:Q9NYU3|uniprotkb:Q5T2C6|uniprotkb:Q5T2C3|uniprotkb:A1L465|uniprotkb:Q5HY99|uniprotkb:Q9NZG4|uniprotkb:Q86WR4|uniprotkb:Q9UF62|uniprotkb:Q9P2W4|uniprotkb:Q9H915|uniprotkb:Q5T2C2|uniprotkb:Q6P600|uniprotkb:Q3MHV4|uniprotkb:Q5T2C4|uniprotkb:Q9Y6E1|ensembl:ENSP00000264183|ensembl:ENSP00000355562 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:ari4b_human(display_long)|uniprotkb:BRCAA1(gene name synonym)|uniprotkb:RBBP1L1(gene name synonym)|uniprotkb:RBP1L1(gene name synonym)|uniprotkb:SAP180(gene name synonym)|uniprotkb:180 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Breast cancer-associated antigen BRCAA1(gene name synonym)|uniprotkb:Histone deacetylase complex subunit SAP180(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 1-like 1(gene name synonym)|uniprotkb:ARID4B(gene name)|psi-mi:ARID4B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483502|imex:IM-26985-201 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N refseq:XP_011542514.1|refseq:NP_001193723.1|refseq:NP_057458.4|refseq:NP_112739.2|ensembl:ENSG00000054267(gene)|ensembl:ENST00000264183(transcript)|ensembl:ENST00000366603(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR002999(Tudor)|interpro:IPR012603(RBB1NT)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR028853|interpro:IPR036431|mint:Q4LE39|rcsb pdb:7DM4|reactome:R-HSA-3214815|reactome:R-HSA-427413|reactome:R-HSA-9679191 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:qvmc05fd/Hu9k0HLB3gRG4ndRp89606 rigid:tLA/YunZf+3g+O4giAYnP4Ty0nA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q8NCD3 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-719429|intact:EBI-2561961|uniprotkb:A8IRH5|uniprotkb:Q9BUT2|uniprotkb:Q9NSL8|uniprotkb:B4DWR0|uniprotkb:B4DZV4|intact:EBI-28976688|ensembl:ENSP00000414109 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:hjurp_human(display_long)|uniprotkb:FAKTS(gene name synonym)|uniprotkb:URLC9(gene name synonym)|uniprotkb:14-3-3-associated AKT substrate(gene name synonym)|uniprotkb:Fetal liver-expressing gene 1 protein(gene name synonym)|uniprotkb:Up-regulated in lung cancer 9(gene name synonym)|uniprotkb:HJURP(gene name)|psi-mi:HJURP(display_short)|uniprotkb:FLEG1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483502|imex:IM-26985-201 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N refseq:NP_001269891.1|refseq:NP_001269892.1|refseq:NP_060880.3|ensembl:ENSP00000414109|ensembl:ENST00000432087|ensembl:ENSP00000407208|ensembl:ENST00000441687|ensembl:ENSP00000401944|ensembl:ENSG00000123485(gene)|ensembl:ENST00000411486(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0007049"(cell cycle)|go:"GO:0007059"(chromosome segregation)|go:"GO:0034080"(CENP-A containing chromatin assembly)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0051101"(regulation of DNA binding)|interpro:IPR018465|interpro:IPR021052|interpro:IPR022102|mint:Q8NCD3|rcsb pdb:3R45|reactome:R-HSA-606279|dip:DIP-53282N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:pUujTbXXH/IPt8rusd4Nef0rfrk9606 rigid:tLA/YunZf+3g+O4giAYnP4Ty0nA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q6ZN18 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-743256|ensembl:ENSP00000381840|uniprotkb:Q59FS5|uniprotkb:Q6ZN62|uniprotkb:Q96BG3 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:aebp2_human(display_long)|uniprotkb:Adipocyte enhancer-binding protein 2(gene name synonym)|uniprotkb:AEBP2(gene name)|psi-mi:AEBP2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483502|imex:IM-26985-201 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N ensembl:ENSG00000139154(gene)|interpro:IPR036236|ensembl:ENST00000398864(transcript)|go:"GO:0000785"(chromatin)|mint:Q6ZN18|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001107648.1|refseq:NP_694939.2|rcsb pdb:5WAI|rcsb pdb:5Y0U|rcsb pdb:5Y1U|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|reactome:R-HSA-3214841|refseq:NP_001253972.1|dip:DIP-58581N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:mOY+NOTaqJlXjW8v6D3YPnfnfBU9606 rigid:tLA/YunZf+3g+O4giAYnP4Ty0nA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q96ST3 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-347218|uniprotkb:Q8N8N4|uniprotkb:Q8NC83|uniprotkb:Q8WV18|uniprotkb:Q96L98|uniprotkb:Q9UFQ1|intact:EBI-28985143|ensembl:ENSP00000353622|ensembl:ENSP00000378402|ensembl:ENSP00000378403|uniprotkb:B2RNS5 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:sin3a_human(display_long)|uniprotkb:SIN3A(gene name)|psi-mi:SIN3A(display_short)|uniprotkb:Transcriptional corepressor Sin3a(gene name synonym)|uniprotkb:Histone deacetylase complex subunit Sin3a(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483502|imex:IM-26985-201 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N refseq:XP_006720528.1|ensembl:ENSG00000169375(gene)|ensembl:ENST00000360439(transcript)|ensembl:ENST00000394947(transcript)|ensembl:ENST00000394949(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007568"(aging)|go:"GO:0010817"(regulation of hormone levels)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0031937"(obsolete positive regulation of chromatin silencing)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0051595"(response to methylglyoxal)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1901675"(negative regulation of histone H3-K27 acetylation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR003822(Paired amphipathic helix)|interpro:IPR013194(Histone deacetylase interacting)|interpro:IPR031693|interpro:IPR036600|interpro:IPR037969|interpro:IPR039774|mint:Q96ST3|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-427413|reactome:R-HSA-8936459|reactome:R-HSA-9022538|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9022702|rcsb pdb:1PO4|reactome:R-HSA-9615017|reactome:R-HSA-9707564|reactome:R-HSA-983231|refseq:XP_006720529.1|refseq:XP_006720530.1|refseq:NP_001138829.1|refseq:NP_001138830.1|refseq:NP_056292.1|ensembl:ENSP00000353622|ensembl:ENSP00000378402|ensembl:ENSP00000378403|dip:DIP-31515N - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:pO/FziDcMNQRfy6ePi6eNKELXVM9606 rigid:tLA/YunZf+3g+O4giAYnP4Ty0nA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:O75182 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-540462|uniprotkb:Q68GC2|uniprotkb:Q6P4B8|uniprotkb:Q8TB34|uniprotkb:Q9BSC8|uniprotkb:Q2NL91|ensembl:ENSP00000369131 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:sin3b_human(display_long)|uniprotkb:Transcriptional corepressor Sin3b(gene name synonym)|uniprotkb:Histone deacetylase complex subunit Sin3b(gene name synonym)|uniprotkb:SIN3B(gene name)|psi-mi:SIN3B(display_short)|uniprotkb:KIAA0700(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483502|imex:IM-26985-201 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N refseq:NP_056075.1|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0030849"(autosome)|interpro:IPR003822(Paired amphipathic helix)|interpro:IPR013194(Histone deacetylase interacting)|interpro:IPR031693|go:"GO:0003682"(chromatin binding)|interpro:IPR036600|interpro:IPR039774|mint:O75182|reactome:R-HSA-400206|reactome:R-HSA-427413|reactome:R-HSA-8936459|reactome:R-HSA-9707564|ensembl:ENSG00000127511(gene)|ensembl:ENST00000379803(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000805"(X chromosome)|go:"GO:0000806"(Y chromosome)|go:"GO:0001741"(XY body)|refseq:NP_001284524.1|refseq:NP_001284526.1 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:ney2nq8TMh2sFxskgXr+NgNCl349606 rigid:tLA/YunZf+3g+O4giAYnP4Ty0nA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q96KM6 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-1049952|uniprotkb:Q08AK9|uniprotkb:Q9ULM4|ensembl:ENSP00000358904 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:z512b_human(display_long)|uniprotkb:ZNF512B(gene name)|psi-mi:ZNF512B(display_short)|uniprotkb:KIAA1196(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483502|imex:IM-26985-201 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N refseq:NP_065764.1|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q96KM6|rcsb pdb:2GQJ|reactome:R-HSA-9013424|go:"GO:0046872"(metal ion binding)|ensembl:ENSG00000196700(gene)|ensembl:ENST00000369888(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|refseq:XP_011527231.1 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:kdtiH1kX3fw2Si0UVegJb6AS+709606 rigid:tLA/YunZf+3g+O4giAYnP4Ty0nA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q96JN0 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-746045|uniprotkb:Q9H945|uniprotkb:Q9Y457|ensembl:ENSP00000348298|ensembl:ENSP00000360138|ensembl:ENSP00000360144|ensembl:ENSP00000501560|ensembl:ENSP00000501639|ensembl:ENSP00000502633|intact:EBI-8833163|uniprotkb:D3DR47|uniprotkb:Q5VW16|uniprotkb:Q7Z723|uniprotkb:Q86T32|uniprotkb:Q86T33|uniprotkb:Q8N3L6|uniprotkb:Q8N655 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:lcor_human(display_long)|uniprotkb:LCOR(gene name)|psi-mi:LCOR(display_short)|uniprotkb:C10orf12(gene name synonym)|uniprotkb:KIAA1795(gene name synonym)|uniprotkb:MLR2(gene name synonym)|uniprotkb:Mblk1-related protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483502|imex:IM-26985-201 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N ensembl:ENSG00000196233(gene)|ensembl:ENST00000356016(transcript)|ensembl:ENST00000371097(transcript)|ensembl:ENST00000371103(transcript)|ensembl:ENST00000675471(transcript)|ensembl:ENST00000675537(transcript)|ensembl:ENST00000675971(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990381"(ubiquitin-specific protease binding)|interpro:IPR007889(Helix-turn-helix, Psq)|interpro:IPR009057(Homeodomain-like)|mint:Q96JN0|rcsb pdb:2COB|refseq:NP_001164236.1|refseq:NP_001164237.1|refseq:NP_115816.2|refseq:XP_016872275.1|refseq:XP_016872276.1|refseq:XP_016872277.1|refseq:NP_001333445.1 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:cOnk6EDDff86yaG1uG+dxEQ1Z689606 rigid:tLA/YunZf+3g+O4giAYnP4Ty0nA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q9H7L9 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-540496|uniprotkb:Q4KMQ5|uniprotkb:Q8N6H0|uniprotkb:Q9H8D2|ensembl:ENSP00000443988 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:sds3_human(display_long)|uniprotkb:Suppressor of defective silencing 3 protein homolog(gene name synonym)|uniprotkb:45 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:SUDS3(gene name)|psi-mi:SUDS3(display_short)|uniprotkb:SAP45(gene name synonym)|uniprotkb:SDS3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483502|imex:IM-26985-201 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N refseq:NP_071936.2|ensembl:ENSG00000111707(gene)|ensembl:ENST00000543473(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016604"(nuclear body)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070822"(Sin3-type complex)|interpro:IPR013907(Sds3-like)|mint:Q9H7L9|reactome:R-HSA-3214815|reactome:R-HSA-427413|reactome:R-HSA-5689880|reactome:R-HSA-9679191 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:gAWv3FGNUAX5PRwGz/eALaA95p09606 rigid:tLA/YunZf+3g+O4giAYnP4Ty0nA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q96N64 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-6597774|uniprotkb:Q2HJJ2|uniprotkb:Q8IYR3|uniprotkb:Q96PV3|uniprotkb:G5EA07|ensembl:ENSP00000305151 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:pwp2a_human(display_long)|uniprotkb:PWWP2A(gene name)|psi-mi:PWWP2A(display_short)|uniprotkb:KIAA1935(gene name synonym)|uniprotkb:MST101(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483502|imex:IM-26985-201 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N refseq:NP_001124336.1|refseq:NP_443159.1|refseq:NP_001253964.1|ensembl:ENSG00000170234(gene)|ensembl:ENST00000307063(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0042393"(histone binding)|interpro:IPR000313(PWWP)|mint:Q96N64 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:dRVLcq751e3y+moSaAoqbKU++HQ9606 rigid:tLA/YunZf+3g+O4giAYnP4Ty0nA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q8WUU5 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-3916882|uniprotkb:D6W5Q5|uniprotkb:Q9H689|uniprotkb:Q8N5Y5|uniprotkb:Q99995|uniprotkb:B2RE37|ensembl:ENSP00000287957 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:gatd1_human(display_long)|uniprotkb:GATAD1(gene name)|psi-mi:GATAD1(display_short)|uniprotkb:ODAG(gene name synonym)|uniprotkb:Ocular development-associated gene protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483502|imex:IM-26985-201 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N refseq:NP_066990.3|ensembl:ENSG00000157259(gene)|ensembl:ENST00000287957(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR039050|mint:Q8WUU5 - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:mwq5yOlZTelKYR0VGr822k9K0Nk9606 rigid:tLA/YunZf+3g+O4giAYnP4Ty0nA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q9H165 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-765567|uniprotkb:Q86W14|uniprotkb:Q8WU92|uniprotkb:Q96JL6|uniprotkb:Q9H163|uniprotkb:Q9H164|uniprotkb:Q9H3G9|uniprotkb:Q9NWA7|uniprotkb:D6W5D7|uniprotkb:Q66LN6|ensembl:ENSP00000496168 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:bc11a_human(display_long)|uniprotkb:B-cell CLL/lymphoma 11A(gene name synonym)|uniprotkb:COUP-TF-interacting protein 1(gene name synonym)|uniprotkb:Ecotropic viral integration site 9 protein homolog(gene name synonym)|uniprotkb:BCL11A(gene name)|psi-mi:BCL11A(display_short)|uniprotkb:CTIP1(gene name synonym)|uniprotkb:EVI9(gene name synonym)|uniprotkb:KIAA1809(gene name synonym)|uniprotkb:ZNF856(gene name synonym)|uniprotkb:Zinc finger protein 856(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483502|imex:IM-26985-201 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N refseq:NP_060484.2|refseq:NP_075044.2|refseq:NP_612569.1|refseq:XP_011531211.1|refseq:XP_016859823.1|dip:DIP-45629N|ensembl:ENSG00000119866(gene)|ensembl:ENST00000642384(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001067"(transcription regulatory region nucleic acid binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0032463"(negative regulation of protein homooligomerization)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048671"(negative regulation of collateral sprouting)|go:"GO:0048672"(positive regulation of collateral sprouting)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:1903860"(negative regulation of dendrite extension)|go:"GO:1904800"(negative regulation of neuron remodeling)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9H165|rcsb pdb:5VTB|rcsb pdb:6KI6|rcsb pdb:6U9Q|go:"GO:2000173"(negative regulation of branching morphogenesis of a nerve) - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:xASsLQWykg/7ZpyjLsQP8GlQ/H09606 rigid:tLA/YunZf+3g+O4giAYnP4Ty0nA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q12873 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-523590|uniprotkb:Q9Y4I0|intact:EBI-28978117|ensembl:ENSP00000332628|uniprotkb:D3DTQ9|uniprotkb:E9PG89 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:chd3_human(display_long)|uniprotkb:ATP-dependent helicase CHD3(gene name synonym)|uniprotkb:Mi-2 autoantigen 240 kDa protein(gene name synonym)|uniprotkb:Mi2-alpha(gene name synonym)|uniprotkb:Zinc finger helicase(gene name synonym)|uniprotkb:CHD3(gene name)|psi-mi:CHD3(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483502|imex:IM-26985-201 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N interpro:IPR023780|interpro:IPR027417|interpro:IPR036910|interpro:IPR038718|mint:Q12873|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-4551638|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191|ensembl:ENSG00000170004(gene)|ensembl:ENST00000330494(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007051"(spindle organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0016605"(PML body)|go:"GO:0034451"(centriolar satellite)|go:"GO:0036121"(double-stranded DNA helicase activity)|go:"GO:0043044"|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|go:"GO:0070615"|interpro:IPR019787|interpro:IPR023779|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|ensembl:ENSP00000332628|ensembl:ENST00000358181|ensembl:ENSP00000350907|ensembl:ENST00000380358|ensembl:ENSP00000369716|refseq:NP_001005271.2|refseq:NP_001005273.1|refseq:NP_005843.2|dip:DIP-32496N - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:UjefFUXiV28qhOP9BoIUansxl+k9606 rigid:tLA/YunZf+3g+O4giAYnP4Ty0nA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q5PSV4 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-5666615|intact:EBI-11060846|uniprotkb:Q9BRI4|uniprotkb:A6NFW5|uniprotkb:A6NH45|uniprotkb:B2RD65|ensembl:ENSP00000216807 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:brm1l_human(display_long)|uniprotkb:BRMS1-homolog protein p40(gene name synonym)|uniprotkb:BRMS1-like protein p40(gene name synonym)|uniprotkb:BRMS1L(gene name)|psi-mi:BRMS1L(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483502|imex:IM-26985-201 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N refseq:XP_006720338.1|refseq:NP_115728.2|refseq:XP_016877193.1|refseq:XP_016877194.1|ensembl:ENSG00000100916(gene)|ensembl:ENST00000216807(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0016575"(histone deacetylation)|go:"GO:0040008"(regulation of growth)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0070822"(Sin3-type complex)|interpro:IPR013907(Sds3-like)|mint:Q5PSV4 - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:jVvtmlOL9vQdYz5kAnOi6GksVng9606 rigid:tLA/YunZf+3g+O4giAYnP4Ty0nA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:P10244 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-1389468|uniprotkb:B2RBS5|uniprotkb:B7Z8D9|uniprotkb:F8W6N6|uniprotkb:Q53F07|ensembl:ENSP00000217026 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:mybb_human(display_long)|uniprotkb:Myb-like protein 2(gene name synonym)|uniprotkb:MYBL2(gene name)|psi-mi:MYBL2(display_short)|uniprotkb:BMYB(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483502|imex:IM-26985-201 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N refseq:NP_001265539.1|refseq:NP_002457.1|ensembl:ENSG00000101057(gene)|ensembl:ENST00000217026(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0031523"(Myb complex)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR015395(C-myb, C-terminal)|interpro:IPR017930|interpro:IPR028311|mint:P10244|rcsb pdb:6C48|reactome:R-HSA-1362300|reactome:R-HSA-156711|reactome:R-HSA-8869496 - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:2ldntN2B+u1fHcK4WPkL9UZYbzs9606 rigid:tLA/YunZf+3g+O4giAYnP4Ty0nA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:O75446 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-632609|uniprotkb:D3DP38|ensembl:ENSP00000296504 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:sap30_human(display_long)|uniprotkb:30 kDa Sin3-associated polypeptide(gene name synonym)|uniprotkb:Sin3 corepressor complex subunit SAP30(gene name synonym)|uniprotkb:SAP30(gene name)|psi-mi:SAP30(display_short)|uniprotkb:Sin3-associated polypeptide p30(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483502|imex:IM-26985-201 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N refseq:NP_003855.1|ensembl:ENSG00000164105(gene)|ensembl:ENST00000296504(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0052472"(modulation by host of symbiont transcription)|interpro:IPR024145|interpro:IPR025717|interpro:IPR025718|interpro:IPR038291|mint:O75446|rcsb pdb:2KDP|reactome:R-HSA-3214815|reactome:R-HSA-427413|reactome:R-HSA-9679191|dip:DIP-33328N - - comment:"author score: 28" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:w113AyekZAZr9VOJWcWEFIhqBYA9606 rigid:tLA/YunZf+3g+O4giAYnP4Ty0nA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q92800 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-8830732|uniprotkb:B4E3R7|uniprotkb:O43287|uniprotkb:A6NCH6|uniprotkb:Q14459|uniprotkb:Q53XP3|uniprotkb:B4DSS2|uniprotkb:B4DIJ1|uniprotkb:B4DIZ7|ensembl:ENSP00000404658|ensembl:ENSP00000466924 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:ezh1_human(display_long)|uniprotkb:ENX-2(gene name synonym)|uniprotkb:Enhancer of zeste homolog 1(gene name synonym)|uniprotkb:KIAA0388(gene name synonym)|uniprotkb:EZH1(gene name)|psi-mi:EZH1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483502|imex:IM-26985-201 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N refseq:NP_001308008.1|refseq:NP_001308010.1|refseq:NP_001308011.1|refseq:NP_001982.2|dip:DIP-58580N|ensembl:ENSG00000108799(gene)|ensembl:ENST00000428826(transcript)|ensembl:ENST00000592743(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0021766"(hippocampus development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0031507"(heterochromatin assembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR021654|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR032926|interpro:IPR041343|interpro:IPR041355|interpro:IPR044438|mint:Q92800|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP - - comment:"author score: 29" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:qp3eqBCgiaoA6VSSyqpW1d9YKN49606 rigid:tLA/YunZf+3g+O4giAYnP4Ty0nA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q96GY3 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-748884|uniprotkb:O14557|uniprotkb:Q7Z2T9|uniprotkb:A8KAQ1|ensembl:ENSP00000301159 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:lin37_human(display_long)|uniprotkb:Antolefinin(gene name synonym)|uniprotkb:LIN37(gene name)|psi-mi:LIN37(display_short)|uniprotkb:MSTP064(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483502|imex:IM-26985-201 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N refseq:NP_061977.1|ensembl:ENSG00000267796(gene)|ensembl:ENST00000301159(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005654"(nucleoplasm)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0031523"(Myb complex)|interpro:IPR028226|mint:Q96GY3|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656 - - comment:"author score: 31" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:3AlABMJE4m84S7ZZeYB3tyJbbqw9606 rigid:tLA/YunZf+3g+O4giAYnP4Ty0nA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q5TKA1 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-1389424|uniprotkb:Q5U5L8|uniprotkb:Q5U7E1|uniprotkb:Q6PI55|uniprotkb:Q6ZTV4|uniprotkb:Q7Z3J1|ensembl:ENSP00000505590 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:lin9_human(display_long)|uniprotkb:Beta subunit-associated regulator of apoptosis(gene name synonym)|uniprotkb:Type I interferon receptor beta chain-associated protein(gene name synonym)|uniprotkb:TUDOR gene similar protein(gene name synonym)|uniprotkb:pRB-associated protein(gene name synonym)|uniprotkb:LIN9(gene name)|psi-mi:LIN9(display_short)|uniprotkb:BARA(gene name synonym)|uniprotkb:TGS(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483502|imex:IM-26985-201 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N refseq:NP_775106.2|refseq:NP_001257338.1|refseq:NP_001257339.1|ensembl:ENSG00000183814(gene)|ensembl:ENST00000681046(transcript)|go:"GO:0000003"(reproduction)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0071897"(DNA biosynthetic process)|interpro:IPR010561(DIRP)|interpro:IPR033471|mint:Q5TKA1|rcsb pdb:6C48|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|go:"GO:0017053"(transcription repressor complex) - - comment:"author score: 36" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:ATFX38+7N6NzEysrzMmHvn22jaA9606 rigid:tLA/YunZf+3g+O4giAYnP4Ty0nA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q12830 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-1560273|uniprotkb:Q6NX67|uniprotkb:Q7Z7D6|uniprotkb:Q9UIG2|ensembl:ENSP00000315454 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:bptf_human(display_long)|uniprotkb:Bromodomain and PHD finger-containing transcription factor(gene name synonym)|uniprotkb:Fetal Alzheimer antigen(gene name synonym)|uniprotkb:Fetal Alz-50 clone 1 protein(gene name synonym)|uniprotkb:BPTF(gene name)|psi-mi:BPTF(display_short)|uniprotkb:FAC1(gene name synonym)|uniprotkb:FALZ(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483502|imex:IM-26985-201 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N refseq:NP_004450.3|refseq:NP_872579.2|dip:DIP-38919N|ensembl:ENSG00000171634(gene)|ensembl:ENST00000321892(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007420"(brain development)|go:"GO:0007492"(endoderm development)|go:"GO:0009611"(response to wounding)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016589"(NURF complex)|go:"GO:0030425"(dendrite)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044297"(cell body)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR018359|interpro:IPR018501|interpro:IPR019786|interpro:IPR019787|interpro:IPR028941|interpro:IPR036427|interpro:IPR038028|mint:Q12830|rcsb pdb:2F6J|rcsb pdb:2F6N|rcsb pdb:2FSA|rcsb pdb:2FUI|rcsb pdb:2FUU|rcsb pdb:2RI7|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3UV2|rcsb pdb:5H6Y|rcsb pdb:5R4G|rcsb pdb:5R4H|rcsb pdb:5R4I|rcsb pdb:5R4J|rcsb pdb:5R4K|rcsb pdb:5R4L|rcsb pdb:5R4M|rcsb pdb:5R4N|rcsb pdb:5R4O|rcsb pdb:6AZE|rcsb pdb:7K6R|rcsb pdb:7K6S|rcsb pdb:7KDW|rcsb pdb:7KDZ - - comment:"author score: 38" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:QQehqJ6NUFT7JEUOto64C73imBY9606 rigid:tLA/YunZf+3g+O4giAYnP4Ty0nA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q92769 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-301821|uniprotkb:Q5SRI8|uniprotkb:Q5SZ86|uniprotkb:Q8NEH4|uniprotkb:B4DL58|ensembl:ENSP00000430432|uniprotkb:E1P561|uniprotkb:B3KRS5 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:hdac2_human(display_long)|uniprotkb:HDAC2(gene name)|psi-mi:HDAC2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483502|imex:IM-26985-201 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035094"(response to nicotine)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042220"(response to cocaine)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q92769|rcsb pdb:3MAX|rcsb pdb:4LXZ|rcsb pdb:4LY1|rcsb pdb:5IWG|rcsb pdb:5IX0|rcsb pdb:6G3O|rcsb pdb:6WBW|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|ensembl:ENSG00000196591(gene)|ensembl:ENST00000519065(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|rcsb pdb:6WHN|rcsb pdb:6WHO|rcsb pdb:6WHQ|rcsb pdb:6WHZ|rcsb pdb:6WI3|rcsb pdb:6XDM|rcsb pdb:6XEB|rcsb pdb:6XEC|rcsb pdb:7KBG|rcsb pdb:7KBH|rcsb pdb:7LTG|rcsb pdb:7LTK|rcsb pdb:7LTL|reactome:R-HSA-193670|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9615017|reactome:R-HSA-9619665|reactome:R-HSA-9679191|reactome:R-HSA-983231|rcsb pdb:6WBZ|refseq:NP_001518.3|dip:DIP-24220N|refseq:XP_011534090.1|refseq:XP_016866288.1 - - comment:"author score: 41" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:K4PpGz9E9/TrQZsgvrJuc+uYCn89606 rigid:tLA/YunZf+3g+O4giAYnP4Ty0nA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q13111 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-1020839|uniprotkb:Q7Z7K3|uniprotkb:Q9UJY8|uniprotkb:Q6NXG5|intact:EBI-28985893|ensembl:ENSP00000301280 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:caf1a_human(display_long)|uniprotkb:CHAF1A(gene name)|psi-mi:CHAF1A(display_short)|uniprotkb:CAF(gene name synonym)|uniprotkb:CAF1P150(gene name synonym)|uniprotkb:Chromatin assembly factor I p150 subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483502|imex:IM-26985-201 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N refseq:NP_005474.2|ensembl:ENSG00000167670(gene)|ensembl:ENST00000301280(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070087"(chromo shadow domain binding)|interpro:IPR022043|interpro:IPR029091|interpro:IPR029105|mint:Q13111|ensembl:ENSP00000301280|dip:DIP-31135N - - comment:"author score: 42" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:8ZlQPVvmtN638aK8ZblErN5Bhjo9606 rigid:tLA/YunZf+3g+O4giAYnP4Ty0nA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q9UBB5 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-923391|uniprotkb:Q9UIS8|uniprotkb:O95242|ensembl:ENSP00000256429 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:mbd2_human(display_long)|uniprotkb:MBD2(gene name)|psi-mi:MBD2(display_short)|uniprotkb:Methyl-CpG-binding protein MBD2(gene name synonym)|uniprotkb:Demethylase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483502|imex:IM-26985-201 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N refseq:NP_003918.1|refseq:NP_056647.1|ensembl:ENSG00000134046(gene)|ensembl:ENST00000256429(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003696"(satellite DNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034622"|go:"GO:0035197"(siRNA binding)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042711"(maternal behavior)|go:"GO:0043044"|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048568"(embryonic organ development)|go:"GO:0070742"(C2H2 zinc finger domain binding)|go:"GO:0071407"(cellular response to organic cyclic compound)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR025884|interpro:IPR032343|mint:Q9UBB5|rcsb pdb:2L2L|rcsb pdb:6C1A|rcsb pdb:6C1T|rcsb pdb:6C1U|rcsb pdb:6C1V|rcsb pdb:6C2F|rcsb pdb:6CNP|rcsb pdb:6CNQ|rcsb pdb:7AO8|rcsb pdb:7AO9|rcsb pdb:7AOA|reactome:R-HSA-427413|reactome:R-HSA-73728 - - comment:"author score: 45" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:8DO+M6oIpbSfTFPVLADdXaaqzEU9606 rigid:tLA/YunZf+3g+O4giAYnP4Ty0nA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q14839 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-372916|uniprotkb:Q8IXZ5|intact:EBI-28978241|ensembl:ENSP00000440542 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:chd4_human(display_long)|uniprotkb:CHD4(gene name)|psi-mi:CHD4(display_short)|uniprotkb:ATP-dependent helicase CHD4(gene name synonym)|uniprotkb:Mi-2 autoantigen 218 kDa protein(gene name synonym)|uniprotkb:Mi2-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483502|imex:IM-26985-201 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N ensembl:ENSP00000440542|ensembl:ENST00000645095|ensembl:ENSP00000496634|refseq:NP_001264.2|refseq:XP_006719021.1|refseq:NP_001284482.1|ensembl:ENSG00000111642(gene)|ensembl:ENST00000544040(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070615"|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR009462(Protein of unknown function DUF1086)|interpro:IPR009463(Protein of unknown function DUF1087)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR012957(CHD, C-terminal 2)|interpro:IPR012958(CHD, N-terminal)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like)|interpro:IPR019786|interpro:IPR019787|interpro:IPR023780|interpro:IPR027417|interpro:IPR038718|mint:Q14839|rcsb pdb:1MM2|rcsb pdb:1MM3|rcsb pdb:2EE1|rcsb pdb:2L5U|rcsb pdb:2L75|rcsb pdb:2N5N|rcsb pdb:4O9I|rcsb pdb:6BGG|rcsb pdb:6Q3M|rcsb pdb:6RYR|rcsb pdb:6RYU|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9031628|reactome:R-HSA-9679191|dip:DIP-31183N - - comment:"author score: 47" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:E9eHT/41SIFRiz54J81hvPQeHIE9606 rigid:tLA/YunZf+3g+O4giAYnP4Ty0nA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q9BTC8 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-2461787|uniprotkb:Q9NSP2|uniprotkb:Q9ULF4|ensembl:ENSP00000385823 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:mta3_human(display_long)|uniprotkb:MTA3(gene name)|psi-mi:MTA3(display_short)|uniprotkb:KIAA1266(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483502|imex:IM-26985-201 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N refseq:NP_001269684.1|refseq:NP_001269685.1|refseq:NP_065795.1|refseq:NP_001317371.1|dip:DIP-47460N|ensembl:ENST00000405094(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR035170|interpro:IPR040138|interpro:IPR043151|mint:Q9BTC8|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191|ensembl:ENSG00000057935(gene) - - comment:"author score: 47" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:wxPsfH6FguY8n4PFwaj1iJNTWPc9606 rigid:tLA/YunZf+3g+O4giAYnP4Ty0nA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:O14519 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-1052532|uniprotkb:F5GYA4|intact:EBI-10988349|ensembl:ENSP00000261692 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:cdka1_human(display_long)|uniprotkb:Putative oral cancer suppressor(gene name synonym)|uniprotkb:Deleted in oral cancer 1(gene name synonym)|uniprotkb:CDK2AP1(gene name)|psi-mi:CDK2AP1(display_short)|uniprotkb:CDKAP1(gene name synonym)|uniprotkb:DOC1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483502|imex:IM-26985-201 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N refseq:NP_004633.1|refseq:NP_001257362.1|refseq:NP_001257363.1|ensembl:ENSG00000111328(gene)|ensembl:ENST00000261692(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0007049"(cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070182"(DNA polymerase binding)|interpro:IPR017266(Cyclin-dependent kinase 2-associated protein 2)|mint:O14519|rcsb pdb:2KW6 - - comment:"author score: 50" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:ZFfQSqkET3VpjG8UrdHokYRGzj09606 rigid:tLA/YunZf+3g+O4giAYnP4Ty0nA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q86YP4 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-726224|uniprotkb:Q7L3J2|uniprotkb:Q96F28|uniprotkb:Q9NPU2|uniprotkb:Q9NXS1|uniprotkb:B5MC40|ensembl:ENSP00000351552|ensembl:ENSP00000353463 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:p66a_human(display_long)|uniprotkb:GATA zinc finger domain-containing protein 2A(gene name synonym)|uniprotkb:GATAD2A(gene name)|psi-mi:GATAD2A(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483502|imex:IM-26985-201 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N refseq:NP_060130.3|refseq:NP_001287875.1|refseq:XP_011526407.1|ensembl:ENSG00000167491(gene)|ensembl:ENST00000358713(transcript)|ensembl:ENST00000360315(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR032346|interpro:IPR040386|mint:Q86YP4|rcsb pdb:2L2L|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191|dip:DIP-36053N - - comment:"author score: 54" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:s2G27yMihH9d7ny/v1GZ7aeTpDQ9606 rigid:tLA/YunZf+3g+O4giAYnP4Ty0nA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:O75530 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-923794|intact:EBI-2839778|intact:EBI-1177693|uniprotkb:A8K7V5|uniprotkb:Q6NTH2|uniprotkb:Q7LDA5|uniprotkb:Q7LDG8|uniprotkb:Q86VV2|uniprotkb:Q9UNY7|uniprotkb:O00149|ensembl:ENSP00000263360|ensembl:ENSP00000500834 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:eed_human(display_long)|uniprotkb:EED(gene name)|psi-mi:EED(display_short)|uniprotkb:WD protein associating with integrin cytoplasmic tails 1(gene name synonym)|uniprotkb:Embryonic ectoderm development protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483502|imex:IM-26985-201 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N refseq:NP_003788.2|refseq:NP_001294936.1|dip:DIP-36673N|ensembl:ENSG00000074266(gene)|ensembl:ENST00000263360(transcript)|ensembl:ENST00000672825(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0021510"(spinal cord development)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:O75530|rcsb pdb:3IIW|rcsb pdb:3IIY|rcsb pdb:3IJ0|rcsb pdb:3IJ1|rcsb pdb:3IJC|rcsb pdb:3JPX|rcsb pdb:3JZG|rcsb pdb:3JZH|rcsb pdb:3JZN|rcsb pdb:3K26|rcsb pdb:3K27|rcsb pdb:4W2R|rcsb pdb:4X3E|rcsb pdb:5GSA|rcsb pdb:5H13|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5K0M|rcsb pdb:5LS6|rcsb pdb:5TTW|rcsb pdb:5U5H|rcsb pdb:5U5K|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5U69|rcsb pdb:5U6D|rcsb pdb:5U8A|rcsb pdb:5U8F|rcsb pdb:5WG6|rcsb pdb:5WP3|rcsb pdb:5WUK|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6SFB|rcsb pdb:6SFC|rcsb pdb:6U4Y|rcsb pdb:6V3X|rcsb pdb:6V3Y|rcsb pdb:6W7F|rcsb pdb:6W7G|rcsb pdb:6WKR|rcsb pdb:6YVI|rcsb pdb:6YVJ|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7KXT|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421 - - comment:"author score: 72" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA9606 rigid:tLA/YunZf+3g+O4giAYnP4Ty0nA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q8WXI9 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-923440|uniprotkb:Q5VUR2|uniprotkb:Q7LG68|uniprotkb:Q9ULS0|uniprotkb:D3DUZ2|ensembl:ENSP00000357644|ensembl:ENSP00000458280|ensembl:ENSP00000489184 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:p66b_human(display_long)|uniprotkb:GATAD2B(gene name)|psi-mi:GATAD2B(display_short)|uniprotkb:KIAA1150(gene name synonym)|uniprotkb:p66/p68(gene name synonym)|uniprotkb:GATA zinc finger domain-containing protein 2B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483502|imex:IM-26985-201 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N refseq:NP_065750.1|refseq:XP_005245421.1|dip:DIP-36054N|ensembl:ENSG00000143614(gene)|ensembl:ENSG00000261992(gene)|ensembl:ENST00000368655(transcript)|ensembl:ENST00000576342(transcript)|ensembl:ENST00000634544(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR032346|interpro:IPR040386|mint:Q8WXI9|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191 - - comment:"author score: 72" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:pLKkMcJBBWdyMTf+2axWzvZLKP09606 rigid:tLA/YunZf+3g+O4giAYnP4Ty0nA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:O95983 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-1783068|uniprotkb:Q6PIL9|uniprotkb:Q6PJZ9|uniprotkb:Q86XF4|uniprotkb:A8K4B7|uniprotkb:D6W5Z2|ensembl:ENSP00000412302 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:mbd3_human(display_long)|uniprotkb:MBD3(gene name)|psi-mi:MBD3(display_short)|uniprotkb:Methyl-CpG-binding protein MBD3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483502|imex:IM-26985-201 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N refseq:NP_001268382.1|refseq:NP_001268383.1|dip:DIP-46517N|ensembl:ENSG00000071655(gene)|ensembl:ENST00000434436(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0009888"(tissue development)|go:"GO:0016573"(histone acetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0048568"(embryonic organ development)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR025884|interpro:IPR032343|interpro:IPR037965|mint:O95983|rcsb pdb:2MB7|rcsb pdb:6CC8|rcsb pdb:6CCG|rcsb pdb:6CEU|rcsb pdb:6CEV|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191 - - comment:"author score: 73" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:lm8jh0YVLdljXDhjkTm9B1YSsWA9606 rigid:tLA/YunZf+3g+O4giAYnP4Ty0nA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q15910 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483502|imex:IM-26985-201 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N - - comment:"author score: 73" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 rigid:tLA/YunZf+3g+O4giAYnP4Ty0nA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:Q13330 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-714236|uniprotkb:Q8NFI8|uniprotkb:Q96GI8|uniprotkb:A5PLK4|intact:EBI-28976623|ensembl:ENSP00000333633|uniprotkb:Q86SW2 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:mta1_human(display_long)|uniprotkb:MTA1(gene name)|psi-mi:MTA1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483502|imex:IM-26985-201 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N refseq:NP_001190187.1|refseq:NP_004680.2|ensembl:ENSP00000333633|ensembl:ENST00000405646|ensembl:ENSP00000384180|ensembl:ENST00000438610|ensembl:ENSP00000393438|ensembl:ENSG00000182979(gene)|ensembl:ENST00000331320(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|reactome:R-HSA-427389|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191|reactome:R-HSA-3232118|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007165"(signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR035170|interpro:IPR040138|mint:Q13330|rcsb pdb:4BKX|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:5FXY|rcsb pdb:5ICN|rcsb pdb:6G16|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AO8|go:"GO:0045475"(locomotor rhythm)|rcsb pdb:7AO9|rcsb pdb:7AOA|reactome:R-HSA-3214815|dip:DIP-41751N - - comment:"author score: 77" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:nDDSb5B6YCbq5/6qvgtnUWtP23M9606 rigid:tLA/YunZf+3g+O4giAYnP4Ty0nA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q09028 uniprotkb:O94776 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 intact:EBI-1783035|uniprotkb:Q68DB1|uniprotkb:Q9UQB5|ensembl:ENSP00000278823 psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:mta2_human(display_long)|uniprotkb:MTA2(gene name)|psi-mi:MTA2(display_short)|uniprotkb:MTA1L1(gene name synonym)|uniprotkb:PID(gene name synonym)|uniprotkb:Metastasis-associated 1-like 1(gene name synonym)|uniprotkb:p53 target protein in deacetylase complex(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483502|imex:IM-26985-201 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N refseq:NP_004730.2|refseq:NP_001317221.1|dip:DIP-46519N|ensembl:ENSG00000149480(gene)|ensembl:ENST00000278823(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006306"(DNA methylation)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0016020"(membrane)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR035170|interpro:IPR037964|interpro:IPR040138|interpro:IPR043151|mint:O94776|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191 - - comment:"author score: 107" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rogid:D4wOsdMJYhY/ltvcnnuMHqNrFkc9606 rigid:tLA/YunZf+3g+O4giAYnP4Ty0nA false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:Q92769 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-301821|uniprotkb:Q5SRI8|uniprotkb:Q5SZ86|uniprotkb:Q8NEH4|uniprotkb:B4DL58|ensembl:ENSP00000430432|uniprotkb:E1P561|uniprotkb:B3KRS5 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:hdac2_human(display_long)|uniprotkb:HDAC2(gene name)|psi-mi:HDAC2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483625|imex:IM-26985-569 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009913"(epidermal cell differentiation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016358"(dendrite development)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031000"(response to caffeine)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035094"(response to nicotine)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042220"(response to cocaine)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045347"(negative regulation of MHC class II biosynthetic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0055093"(response to hyperoxia)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0061029"(eyelid development in camera-type eye)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:1902437"(positive regulation of male mating behavior)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR003084(Histone deacetylase)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q92769|rcsb pdb:3MAX|rcsb pdb:4LXZ|rcsb pdb:4LY1|rcsb pdb:5IWG|rcsb pdb:5IX0|rcsb pdb:6G3O|rcsb pdb:6WBW|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|ensembl:ENSG00000196591(gene)|ensembl:ENST00000519065(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001975"(response to amphetamine)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|rcsb pdb:6WHN|rcsb pdb:6WHO|rcsb pdb:6WHQ|rcsb pdb:6WHZ|rcsb pdb:6WI3|rcsb pdb:6XDM|rcsb pdb:6XEB|rcsb pdb:6XEC|rcsb pdb:7KBG|rcsb pdb:7KBH|rcsb pdb:7LTG|rcsb pdb:7LTK|rcsb pdb:7LTL|reactome:R-HSA-193670|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3214815|reactome:R-HSA-350054|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9615017|reactome:R-HSA-9619665|reactome:R-HSA-9679191|reactome:R-HSA-983231|rcsb pdb:6WBZ|refseq:NP_001518.3|dip:DIP-24220N|refseq:XP_011534090.1|refseq:XP_016866288.1 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:K4PpGz9E9/TrQZsgvrJuc+uYCn89606 rigid:PgdZTSRx5Gf2m+oQ3dLNrqZD/DQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:Q96ST3 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-347218|uniprotkb:Q8N8N4|uniprotkb:Q8NC83|uniprotkb:Q8WV18|uniprotkb:Q96L98|uniprotkb:Q9UFQ1|intact:EBI-28985143|ensembl:ENSP00000353622|ensembl:ENSP00000378402|ensembl:ENSP00000378403|uniprotkb:B2RNS5 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:sin3a_human(display_long)|uniprotkb:SIN3A(gene name)|psi-mi:SIN3A(display_short)|uniprotkb:Transcriptional corepressor Sin3a(gene name synonym)|uniprotkb:Histone deacetylase complex subunit Sin3a(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483625|imex:IM-26985-569 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N refseq:XP_006720528.1|ensembl:ENSG00000169375(gene)|ensembl:ENST00000360439(transcript)|ensembl:ENST00000394947(transcript)|ensembl:ENST00000394949(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006476"(protein deacetylation)|go:"GO:0007568"(aging)|go:"GO:0010817"(regulation of hormone levels)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0021895"(cerebral cortex neuron differentiation)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0031937"(obsolete positive regulation of chromatin silencing)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043619"(regulation of transcription from RNA polymerase II promoter in response to oxidative stress)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048511"(rhythmic process)|go:"GO:0051595"(response to methylglyoxal)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:1901675"(negative regulation of histone H3-K27 acetylation)|go:"GO:1903351"(cellular response to dopamine)|go:"GO:2000678"(negative regulation of transcription regulatory region DNA binding)|interpro:IPR003822(Paired amphipathic helix)|interpro:IPR013194(Histone deacetylase interacting)|interpro:IPR031693|interpro:IPR036600|interpro:IPR037969|interpro:IPR039774|mint:Q96ST3|reactome:R-HSA-3899300|reactome:R-HSA-400206|reactome:R-HSA-427413|reactome:R-HSA-8936459|reactome:R-HSA-9022538|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9022702|rcsb pdb:1PO4|reactome:R-HSA-9615017|reactome:R-HSA-9707564|reactome:R-HSA-983231|refseq:XP_006720529.1|refseq:XP_006720530.1|refseq:NP_001138829.1|refseq:NP_001138830.1|refseq:NP_056292.1|ensembl:ENSP00000353622|ensembl:ENSP00000378402|ensembl:ENSP00000378403|dip:DIP-31515N - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:pO/FziDcMNQRfy6ePi6eNKELXVM9606 rigid:PgdZTSRx5Gf2m+oQ3dLNrqZD/DQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:Q86YP4 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-726224|uniprotkb:Q7L3J2|uniprotkb:Q96F28|uniprotkb:Q9NPU2|uniprotkb:Q9NXS1|uniprotkb:B5MC40|ensembl:ENSP00000351552|ensembl:ENSP00000353463 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:p66a_human(display_long)|uniprotkb:GATA zinc finger domain-containing protein 2A(gene name synonym)|uniprotkb:GATAD2A(gene name)|psi-mi:GATAD2A(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483625|imex:IM-26985-569 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N refseq:NP_060130.3|refseq:NP_001287875.1|refseq:XP_011526407.1|ensembl:ENSG00000167491(gene)|ensembl:ENST00000358713(transcript)|ensembl:ENST00000360315(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR032346|interpro:IPR040386|mint:Q86YP4|rcsb pdb:2L2L|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191|dip:DIP-36053N - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:s2G27yMihH9d7ny/v1GZ7aeTpDQ9606 rigid:PgdZTSRx5Gf2m+oQ3dLNrqZD/DQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:Q13330 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-714236|uniprotkb:Q8NFI8|uniprotkb:Q96GI8|uniprotkb:A5PLK4|intact:EBI-28976623|ensembl:ENSP00000333633|uniprotkb:Q86SW2 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:mta1_human(display_long)|uniprotkb:MTA1(gene name)|psi-mi:MTA1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483625|imex:IM-26985-569 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N refseq:NP_001190187.1|refseq:NP_004680.2|ensembl:ENSP00000333633|ensembl:ENST00000405646|ensembl:ENSP00000384180|ensembl:ENST00000438610|ensembl:ENSP00000393438|ensembl:ENSG00000182979(gene)|ensembl:ENST00000331320(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|reactome:R-HSA-427389|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191|reactome:R-HSA-3232118|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007165"(signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0005634"(nucleus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:1902499"(positive regulation of protein autoubiquitination)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR035170|interpro:IPR040138|mint:Q13330|rcsb pdb:4BKX|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:5FXY|rcsb pdb:5ICN|rcsb pdb:6G16|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AO8|go:"GO:0045475"(locomotor rhythm)|rcsb pdb:7AO9|rcsb pdb:7AOA|reactome:R-HSA-3214815|dip:DIP-41751N - - comment:"author score: 29" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:nDDSb5B6YCbq5/6qvgtnUWtP23M9606 rigid:PgdZTSRx5Gf2m+oQ3dLNrqZD/DQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:Q09028 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483625|imex:IM-26985-569 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N - - comment:"author score: 29" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rigid:PgdZTSRx5Gf2m+oQ3dLNrqZD/DQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:O95983 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-1783068|uniprotkb:Q6PIL9|uniprotkb:Q6PJZ9|uniprotkb:Q86XF4|uniprotkb:A8K4B7|uniprotkb:D6W5Z2|ensembl:ENSP00000412302 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:mbd3_human(display_long)|uniprotkb:MBD3(gene name)|psi-mi:MBD3(display_short)|uniprotkb:Methyl-CpG-binding protein MBD3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483625|imex:IM-26985-569 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N refseq:NP_001268382.1|refseq:NP_001268383.1|dip:DIP-46517N|ensembl:ENSG00000071655(gene)|ensembl:ENST00000434436(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0007568"(aging)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0009888"(tissue development)|go:"GO:0016573"(histone acetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032355"(response to estradiol)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0048568"(embryonic organ development)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR025884|interpro:IPR032343|interpro:IPR037965|mint:O95983|rcsb pdb:2MB7|rcsb pdb:6CC8|rcsb pdb:6CCG|rcsb pdb:6CEU|rcsb pdb:6CEV|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191 - - comment:"author score: 33" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:lm8jh0YVLdljXDhjkTm9B1YSsWA9606 rigid:PgdZTSRx5Gf2m+oQ3dLNrqZD/DQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:Q8WXI9 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-923440|uniprotkb:Q5VUR2|uniprotkb:Q7LG68|uniprotkb:Q9ULS0|uniprotkb:D3DUZ2|ensembl:ENSP00000357644|ensembl:ENSP00000458280|ensembl:ENSP00000489184 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:p66b_human(display_long)|uniprotkb:GATAD2B(gene name)|psi-mi:GATAD2B(display_short)|uniprotkb:KIAA1150(gene name synonym)|uniprotkb:p66/p68(gene name synonym)|uniprotkb:GATA zinc finger domain-containing protein 2B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483625|imex:IM-26985-569 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N refseq:NP_065750.1|refseq:XP_005245421.1|dip:DIP-36054N|ensembl:ENSG00000143614(gene)|ensembl:ENSG00000261992(gene)|ensembl:ENST00000368655(transcript)|ensembl:ENST00000576342(transcript)|ensembl:ENST00000634544(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016581"(NuRD complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR032346|interpro:IPR040386|mint:Q8WXI9|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191 - - comment:"author score: 35" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:pLKkMcJBBWdyMTf+2axWzvZLKP09606 rigid:PgdZTSRx5Gf2m+oQ3dLNrqZD/DQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:O14929 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-2339359|uniprotkb:Q53SU4|uniprotkb:Q53QF0|uniprotkb:Q49A44|uniprotkb:Q6P594|uniprotkb:Q8WWB9|ensembl:ENSP00000264108 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:hat1_human(display_long)|uniprotkb:HAT1(gene name)|psi-mi:HAT1(display_short)|uniprotkb:KAT1(gene name synonym)|uniprotkb:Histone acetyltransferase 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483625|imex:IM-26985-569 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N refseq:NP_003633.1|dip:DIP-52811N|ensembl:ENSG00000128708(gene)|ensembl:ENST00000264108(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006323"(DNA packaging)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006348"|go:"GO:0006475"(internal protein amino acid acetylation)|go:"GO:0007584"(response to nutrient)|go:"GO:0010485"(H4 histone acetyltransferase activity)|go:"GO:0016363"(nuclear matrix)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR013523(Histone acetyltransferase HAT1, C-terminal)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR017380(Histone acetyltransferase type B, catalytic subunit)|interpro:IPR019467|interpro:IPR037113|mint:O14929|rcsb pdb:2P0W|rcsb pdb:6VO5|reactome:R-HSA-3214847 - - comment:"author score: 42" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:80KgRaid3NeRfAUdTHMQ/r0VuGo9606 rigid:PgdZTSRx5Gf2m+oQ3dLNrqZD/DQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16576 uniprotkb:O94776 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 intact:EBI-1783035|uniprotkb:Q68DB1|uniprotkb:Q9UQB5|ensembl:ENSP00000278823 psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:mta2_human(display_long)|uniprotkb:MTA2(gene name)|psi-mi:MTA2(display_short)|uniprotkb:MTA1L1(gene name synonym)|uniprotkb:PID(gene name synonym)|uniprotkb:Metastasis-associated 1-like 1(gene name synonym)|uniprotkb:p53 target protein in deacetylase complex(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483625|imex:IM-26985-569 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N refseq:NP_004730.2|refseq:NP_001317221.1|dip:DIP-46519N|ensembl:ENSG00000149480(gene)|ensembl:ENST00000278823(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006306"(DNA methylation)|go:"GO:0006333"(chromatin assembly or disassembly)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010762"(regulation of fibroblast migration)|go:"GO:0016020"(membrane)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016581"(NuRD complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR035170|interpro:IPR037964|interpro:IPR040138|interpro:IPR043151|mint:O94776|reactome:R-HSA-3214815|reactome:R-HSA-427389|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-9679191 - - comment:"author score: 44" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rogid:D4wOsdMJYhY/ltvcnnuMHqNrFkc9606 rigid:PgdZTSRx5Gf2m+oQ3dLNrqZD/DQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5S9 uniprotkb:Q9BRP8 intact:EBI-447231|uniprotkb:Q6FHD1|uniprotkb:Q6IQ40|uniprotkb:Q9GZX8|uniprotkb:Q9NZI4|uniprotkb:B3KQI9|intact:EBI-28979675|ensembl:ENSP00000463058|ensembl:ENSP00000488265 intact:EBI-2352802|uniprotkb:Q8IXJ8|uniprotkb:Q8N8E7|uniprotkb:B6ZDM5|ensembl:ENSP00000386156 psi-mi:rbm8a_human(display_long)|uniprotkb:HSPC114(orf name)|uniprotkb:MDS014(orf name)|uniprotkb:RNA-binding motif protein 8A(gene name synonym)|uniprotkb:Ribonucleoprotein RBM8A(gene name synonym)|uniprotkb:RNA-binding protein Y14(gene name synonym)|uniprotkb:Binder of OVCA1-1(gene name synonym)|uniprotkb:RBM8A(gene name)|psi-mi:RBM8A(display_short)|uniprotkb:RBM8(gene name synonym) psi-mi:pym1_human(display_long)|uniprotkb:PYM1(gene name)|psi-mi:PYM1(display_short)|uniprotkb:PYM(gene name synonym)|uniprotkb:PYM homolog 1 exon junction complex-associated factor(gene name synonym)|uniprotkb:Protein wibg homolog(gene name synonym)|uniprotkb:WIBG(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483658|imex:IM-26985-269 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005096.1|ensembl:ENST00000369307|ensembl:ENSP00000358313|ensembl:ENSP00000463058|ensembl:ENSP00000488265|dip:DIP-33070N|ensembl:ENSG00000265241(gene)|ensembl:ENST00000583313(transcript)|ensembl:ENST00000632555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0030425"(dendrite)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051028"(mRNA transport)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR008111(RNA binding motif protein 8)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033744|interpro:IPR035979|mint:Q9Y5S9|rcsb pdb:1P27|rcsb pdb:2HYI|rcsb pdb:2J0Q|rcsb pdb:2J0S|rcsb pdb:2XB2|rcsb pdb:3EX7|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:6ICZ|rcsb pdb:6QDV|rcsb pdb:7A5P|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9010553|reactome:R-HSA-975957 refseq:NP_001137325.1|refseq:NP_115721.1|dip:DIP-48413N|ensembl:ENSG00000170473(gene)|ensembl:ENST00000408946(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030054"(cell junction)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:1903259"(exon-exon junction complex disassembly)|interpro:IPR015362(Exon junction complex, Pym)|interpro:IPR036348|interpro:IPR039333|mint:Q9BRP8 - - comment:"author score: 63" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:7WdTcDs4RqjiKDSkHF0fFD8rAb09606 rogid:REnCXPEpBBYprj7V0RQLJecl+Ug9606 rigid:s/U4lQzyCH/SsXPBQjspwtTUzNE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y5S9 uniprotkb:P61326 intact:EBI-447231|uniprotkb:Q6FHD1|uniprotkb:Q6IQ40|uniprotkb:Q9GZX8|uniprotkb:Q9NZI4|uniprotkb:B3KQI9|intact:EBI-28979675|ensembl:ENSP00000463058|ensembl:ENSP00000488265 intact:EBI-299134|ensembl:ENSP00000360525|uniprotkb:O35169|uniprotkb:P50606|uniprotkb:Q5SW69|uniprotkb:B2R5A2|uniprotkb:B1ARP8 psi-mi:rbm8a_human(display_long)|uniprotkb:HSPC114(orf name)|uniprotkb:MDS014(orf name)|uniprotkb:RNA-binding motif protein 8A(gene name synonym)|uniprotkb:Ribonucleoprotein RBM8A(gene name synonym)|uniprotkb:RNA-binding protein Y14(gene name synonym)|uniprotkb:Binder of OVCA1-1(gene name synonym)|uniprotkb:RBM8A(gene name)|psi-mi:RBM8A(display_short)|uniprotkb:RBM8(gene name synonym) psi-mi:mgn_human(display_long)|uniprotkb:MAGOH(gene name)|psi-mi:MAGOH(display_short)|uniprotkb:MAGOHA(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483658|imex:IM-26985-269 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005096.1|ensembl:ENST00000369307|ensembl:ENSP00000358313|ensembl:ENSP00000463058|ensembl:ENSP00000488265|dip:DIP-33070N|ensembl:ENSG00000265241(gene)|ensembl:ENST00000583313(transcript)|ensembl:ENST00000632555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0030425"(dendrite)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051028"(mRNA transport)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR008111(RNA binding motif protein 8)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033744|interpro:IPR035979|mint:Q9Y5S9|rcsb pdb:1P27|rcsb pdb:2HYI|rcsb pdb:2J0Q|rcsb pdb:2J0S|rcsb pdb:2XB2|rcsb pdb:3EX7|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:6ICZ|rcsb pdb:6QDV|rcsb pdb:7A5P|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9010553|reactome:R-HSA-975957 ensembl:ENSG00000162385(gene)|ensembl:ENST00000371470(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0035145"(exon-exon junction complex)|go:"GO:0051028"(mRNA transport)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR004023(Mago nashi protein)|interpro:IPR036605|mint:P61326|rcsb pdb:1P27|rcsb pdb:2HYI|rcsb pdb:2J0Q|rcsb pdb:2J0S|rcsb pdb:2XB2|rcsb pdb:3EX7|rcsb pdb:7A5P|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9010553|reactome:R-HSA-975957|refseq:NP_002361.1|dip:DIP-33069N - - comment:"author score: 94" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:7WdTcDs4RqjiKDSkHF0fFD8rAb09606 rogid:QwhNt2LtYudXCggVAqBsZm/hWAA9606 rigid:s/U4lQzyCH/SsXPBQjspwtTUzNE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A6NED2 uniprotkb:P47929 intact:EBI-21552314|ensembl:ENSP00000377801|ensembl:ENSP00000451963|uniprotkb:B2RTP9|uniprotkb:Q29RX6 intact:EBI-357504|ensembl:ENSP00000313571|ensembl:ENSP00000367891|ensembl:ENSP00000489395|ensembl:ENSP00000489582|uniprotkb:Q6IB87 psi-mi:rccd1_human(display_long)|uniprotkb:RCCD1(gene name)|psi-mi:RCCD1(display_short) psi-mi:leg7_human(display_long)|uniprotkb:LGALS7(gene name)|psi-mi:LGALS7(display_short)|uniprotkb:PIG1(gene name synonym)|uniprotkb:HKL-14(gene name synonym)|uniprotkb:PI7(gene name synonym)|uniprotkb:p53-induced gene 1 protein(gene name synonym)|uniprotkb:LGALS7B(gene name)|psi-mi:LGALS7B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483670|imex:IM-26985-571 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166965(gene)|ensembl:ENST00000394258(transcript)|ensembl:ENST00000556618(transcript)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|mint:A6NED2|rcsb pdb:6F4R|rcsb pdb:6F4S|rcsb pdb:6F4T|refseq:NP_001017919.1|refseq:NP_291022.2 ensembl:ENSG00000178934(gene)|ensembl:ENSG00000205076(gene)|ensembl:ENSG00000282902(gene)|ensembl:ENSG00000283082(gene)|ensembl:ENST00000314980(transcript)|ensembl:ENST00000378626(transcript)|ensembl:ENST00000634448(transcript)|ensembl:ENST00000634800(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016936"(galactoside binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000562"(negative regulation of CD4-positive, alpha-beta T cell proliferation)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR030640|interpro:IPR044156|mint:P47929|rcsb pdb:1BKZ|rcsb pdb:2GAL|rcsb pdb:3GAL|rcsb pdb:3ZXE|rcsb pdb:3ZXF|rcsb pdb:4GAL|rcsb pdb:4UW3|rcsb pdb:4UW4|rcsb pdb:4UW5|rcsb pdb:4UW6|rcsb pdb:4XBQ|rcsb pdb:4Y26|rcsb pdb:5GAL|rcsb pdb:5H9Q|rcsb pdb:5H9S|refseq:NP_001035972.1|refseq:NP_002298.1 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pJ4TNM7dmfISs5RIVzio/hBYHp09606 rogid:TIAlvVZ7rOYqTAGrYAFbJY231gc9606 rigid:q1FGjYkJsmPqoGwwXuNjDD5TV/M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A6NED2 uniprotkb:P01040 intact:EBI-21552314|ensembl:ENSP00000377801|ensembl:ENSP00000451963|uniprotkb:B2RTP9|uniprotkb:Q29RX6 intact:EBI-724303|ensembl:ENSP00000264474|uniprotkb:Q6IB90 psi-mi:rccd1_human(display_long)|uniprotkb:RCCD1(gene name)|psi-mi:RCCD1(display_short) psi-mi:cyta_human(display_long)|uniprotkb:Cystatin-AS(gene name synonym)|uniprotkb:Stefin-A(gene name synonym)|uniprotkb:CSTA(gene name)|psi-mi:CSTA(display_short)|uniprotkb:STF1(gene name synonym)|uniprotkb:STFA(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483670|imex:IM-26985-571 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166965(gene)|ensembl:ENST00000394258(transcript)|ensembl:ENST00000556618(transcript)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|mint:A6NED2|rcsb pdb:6F4R|rcsb pdb:6F4S|rcsb pdb:6F4T|refseq:NP_001017919.1|refseq:NP_291022.2 refseq:NP_005204.1|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR001713(Proteinase inhibitor I25A, stefin A)|mint:P01040|rcsb pdb:1CYU|rcsb pdb:1CYV|rcsb pdb:1DVC|rcsb pdb:1DVD|rcsb pdb:1GD3|rcsb pdb:1GD4|rcsb pdb:1N9J|rcsb pdb:1NB3|rcsb pdb:1NB5|rcsb pdb:3K9M|rcsb pdb:3KFQ|interpro:IPR018073|rcsb pdb:3KSE|reactome:R-HSA-6809371|ensembl:ENSG00000121552(gene)|ensembl:ENST00000264474(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002020"(protease binding)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0045861"(negative regulation of proteolysis) - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pJ4TNM7dmfISs5RIVzio/hBYHp09606 rogid:SzbpyWUHlOtItIvffzuwhcqFsDI9606 rigid:q1FGjYkJsmPqoGwwXuNjDD5TV/M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A6NED2 uniprotkb:O60271 intact:EBI-21552314|ensembl:ENSP00000377801|ensembl:ENSP00000451963|uniprotkb:B2RTP9|uniprotkb:Q29RX6 intact:EBI-1023301|uniprotkb:O60905|uniprotkb:Q3KQU8|uniprotkb:Q3MKM7|uniprotkb:Q86WC7|uniprotkb:Q86WC8|uniprotkb:Q8IZX7|uniprotkb:Q96II0|uniprotkb:Q9H811|uniprotkb:A8MSX0|uniprotkb:B4DHH2|uniprotkb:A6H8U5|intact:EBI-2560890|ensembl:ENSP00000262013 psi-mi:rccd1_human(display_long)|uniprotkb:RCCD1(gene name)|psi-mi:RCCD1(display_short) psi-mi:jip4_human(display_long)|uniprotkb:JNK-associated leucine-zipper protein(gene name synonym)|uniprotkb:Sperm-associated antigen 9(gene name synonym)|uniprotkb:Mitogen-activated protein kinase 8-interacting protein 4(gene name synonym)|uniprotkb:Human lung cancer oncogene 6 protein(gene name synonym)|uniprotkb:Proliferation-inducing protein 6(gene name synonym)|uniprotkb:Sperm-specific protein(gene name synonym)|uniprotkb:Sperm surface protein(gene name synonym)|uniprotkb:Protein highly expressed in testis(gene name synonym)|uniprotkb:Sunday driver 1(gene name synonym)|uniprotkb:Cancer/testis antigen 89(gene name synonym)|uniprotkb:HLC6(orf name)|uniprotkb:SPAG9(gene name)|psi-mi:SPAG9(display_short)|uniprotkb:HSS(gene name synonym)|uniprotkb:KIAA0516(gene name synonym)|uniprotkb:MAPK8IP4(gene name synonym)|uniprotkb:SYD1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483670|imex:IM-26985-571 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166965(gene)|ensembl:ENST00000394258(transcript)|ensembl:ENST00000556618(transcript)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|mint:A6NED2|rcsb pdb:6F4R|rcsb pdb:6F4S|rcsb pdb:6F4T|refseq:NP_001017919.1|refseq:NP_291022.2 refseq:NP_001123999.1|refseq:NP_001238900.1|refseq:NP_001124000.1|refseq:NP_003962.3|ensembl:ENSG00000008294(gene)|ensembl:ENST00000262013(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019894"(kinesin binding)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032418"(lysosome localization)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903860"(negative regulation of dendrite extension)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019143|interpro:IPR032486|interpro:IPR034743|interpro:IPR034744|interpro:IPR036322|interpro:IPR039911|mint:O60271|rcsb pdb:2W83|reactome:R-HSA-525793 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pJ4TNM7dmfISs5RIVzio/hBYHp09606 rogid:UsItS/q6arsUKVnp+hGuBZE3P809606 rigid:q1FGjYkJsmPqoGwwXuNjDD5TV/M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A6NED2 uniprotkb:P04196 intact:EBI-21552314|ensembl:ENSP00000377801|ensembl:ENSP00000451963|uniprotkb:B2RTP9|uniprotkb:Q29RX6 intact:EBI-3915012|uniprotkb:B9EK35|uniprotkb:D3DNU7|ensembl:ENSP00000232003 psi-mi:rccd1_human(display_long)|uniprotkb:RCCD1(gene name)|psi-mi:RCCD1(display_short) psi-mi:hrg_human(display_long)|uniprotkb:HRG(gene name)|psi-mi:HRG(display_short)|uniprotkb:Histidine-proline-rich glycoprotein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483670|imex:IM-26985-571 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166965(gene)|ensembl:ENST00000394258(transcript)|ensembl:ENST00000556618(transcript)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|mint:A6NED2|rcsb pdb:6F4R|rcsb pdb:6F4S|rcsb pdb:6F4T|refseq:NP_001017919.1|refseq:NP_291022.2 refseq:NP_000403.1|ensembl:ENSG00000113905(gene)|ensembl:ENST00000232003(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0002839"(positive regulation of immune response to tumor cell)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0008201"(heparin binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010543"(regulation of platelet activation)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0015886"(heme transport)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0020037"(heme binding)|go:"GO:0030168"(platelet activation)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0033629"(negative regulation of cell adhesion mediated by integrin)|go:"GO:0036019"(endolysosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051838"(cytolysis by host of symbiont cells)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|go:"GO:2000504"(positive regulation of blood vessel remodeling)|go:"GO:2001027"(negative regulation of endothelial cell chemotaxis)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|mint:P04196|reactome:R-HSA-114608|reactome:R-HSA-75205|go:"GO:0043254"(regulation of protein-containing complex assembly)|dip:DIP-47264N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pJ4TNM7dmfISs5RIVzio/hBYHp09606 rogid:o/MnMkd+IKLRtprrFoOapUuoVEs9606 rigid:q1FGjYkJsmPqoGwwXuNjDD5TV/M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A6NED2 uniprotkb:P61758 intact:EBI-21552314|ensembl:ENSP00000377801|ensembl:ENSP00000451963|uniprotkb:B2RTP9|uniprotkb:Q29RX6 intact:EBI-357430|ensembl:ENSP00000286428|uniprotkb:Q15765|uniprotkb:O55228|uniprotkb:Q5JT81|uniprotkb:Q86X96|uniprotkb:B2R8L5|uniprotkb:B4DWR3|uniprotkb:F5H2A7 psi-mi:rccd1_human(display_long)|uniprotkb:RCCD1(gene name)|psi-mi:RCCD1(display_short) psi-mi:pfd3_human(display_long)|uniprotkb:VBP1(gene name)|psi-mi:VBP1(display_short)|uniprotkb:PFDN3(gene name synonym)|uniprotkb:von Hippel-Lindau-binding protein 1(gene name synonym)|uniprotkb:HIBBJ46(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483670|imex:IM-26985-571 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166965(gene)|ensembl:ENST00000394258(transcript)|ensembl:ENST00000556618(transcript)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|mint:A6NED2|rcsb pdb:6F4R|rcsb pdb:6F4S|rcsb pdb:6F4T|refseq:NP_001017919.1|refseq:NP_291022.2 ensembl:ENSG00000155959(gene)|ensembl:ENST00000286428(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006457"(protein folding)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR016655(Prefoldin, subunit 3)|mint:P61758|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957|refseq:NP_003363.1|refseq:NP_001290472.1|refseq:NP_001290474.1|dip:DIP-46479N|refseq:NP_001290473.1 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pJ4TNM7dmfISs5RIVzio/hBYHp09606 rogid:wHq+HRvhqfKwOaKtONGJdfETQxo9606 rigid:q1FGjYkJsmPqoGwwXuNjDD5TV/M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A6NED2 uniprotkb:Q96CX2 intact:EBI-21552314|ensembl:ENSP00000377801|ensembl:ENSP00000451963|uniprotkb:B2RTP9|uniprotkb:Q29RX6 intact:EBI-358358|ensembl:ENSP00000366694 psi-mi:rccd1_human(display_long)|uniprotkb:RCCD1(gene name)|psi-mi:RCCD1(display_short) psi-mi:kcd12_human(display_long)|uniprotkb:KCTD12(gene name)|psi-mi:KCTD12(display_short)|uniprotkb:C13orf2(gene name synonym)|uniprotkb:KIAA1778(gene name synonym)|uniprotkb:PFET1(gene name synonym)|uniprotkb:Pfetin(gene name synonym)|uniprotkb:Predominantly fetal expressed T1 domain(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483670|imex:IM-26985-571 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166965(gene)|ensembl:ENST00000394258(transcript)|ensembl:ENST00000556618(transcript)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|mint:A6NED2|rcsb pdb:6F4R|rcsb pdb:6F4S|rcsb pdb:6F4T|refseq:NP_001017919.1|refseq:NP_291022.2 refseq:NP_612453.1|ensembl:ENSG00000178695(gene)|ensembl:ENST00000377474(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0051260"(protein homooligomerization)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR003131(Potassium channel, voltage dependent, Kv, tetramerisation)|interpro:IPR011333(BTB/POZ fold)|mint:Q96CX2|rcsb pdb:6M8S|rcsb pdb:6QZL - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pJ4TNM7dmfISs5RIVzio/hBYHp09606 rogid:Xxp3in+fgJzZXJaorHFWXTbyKKQ9606 rigid:q1FGjYkJsmPqoGwwXuNjDD5TV/M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A6NED2 uniprotkb:Q8N371 intact:EBI-21552314|ensembl:ENSP00000377801|ensembl:ENSP00000451963|uniprotkb:B2RTP9|uniprotkb:Q29RX6 intact:EBI-750326|uniprotkb:B4DLU9|uniprotkb:Q6VAK5|uniprotkb:Q9H8B1|ensembl:ENSP00000286096 psi-mi:rccd1_human(display_long)|uniprotkb:RCCD1(gene name)|psi-mi:RCCD1(display_short) psi-mi:kdm8_human(display_long)|uniprotkb:KDM8(gene name)|psi-mi:KDM8(display_short)|uniprotkb:JMJD5(gene name synonym)|uniprotkb:JmjC domain-containing protein 5(gene name synonym)|uniprotkb:Jumonji C domain-containing protein 5(gene name synonym)|uniprotkb:"L-arginine (3R)-hydroxylase KDM8"(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483670|imex:IM-26985-571 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000166965(gene)|ensembl:ENST00000394258(transcript)|ensembl:ENST00000556618(transcript)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|mint:A6NED2|rcsb pdb:6F4R|rcsb pdb:6F4S|rcsb pdb:6F4T|refseq:NP_001017919.1|refseq:NP_291022.2 refseq:NP_001138820.1|refseq:NP_079049.2|ensembl:ENSG00000155666(gene)|ensembl:ENST00000286096(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0003682"(chromatin binding)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0031648"(protein destabilization)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035064"(methylated histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:0140554"|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR041667|mint:Q8N371|rcsb pdb:3UYJ|rcsb pdb:4AAP|rcsb pdb:6F4T|rcsb pdb:6I9L|rcsb pdb:6I9M|rcsb pdb:6I9N|rcsb pdb:4GAZ|rcsb pdb:4GJY|rcsb pdb:4GJZ|rcsb pdb:4QU1|rcsb pdb:5FBJ|rcsb pdb:6AVS|rcsb pdb:6AX3|rcsb pdb:6F4M|rcsb pdb:6F4N|rcsb pdb:6F4O|rcsb pdb:6F4P|rcsb pdb:6F4Q|rcsb pdb:6F4R|rcsb pdb:6F4S - - comment:"author score: 191" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pJ4TNM7dmfISs5RIVzio/hBYHp09606 rogid:xMY4ykJyXdyFo1lNfe6RekrAAhE9606 rigid:q1FGjYkJsmPqoGwwXuNjDD5TV/M false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NS91 uniprotkb:P04908 intact:EBI-2339393|uniprotkb:Q9NRT6|uniprotkb:Q58F55|ensembl:ENSP00000264926 intact:EBI-358971|uniprotkb:Q76P63|uniprotkb:P28001|ensembl:ENSP00000303373|ensembl:ENSP00000483842 psi-mi:rad18_human(display_long)|uniprotkb:RAD18(gene name)|psi-mi:RAD18(display_short)|uniprotkb:RNF73(gene name synonym)|uniprotkb:Postreplication repair protein RAD18(gene name synonym)|uniprotkb:RING finger protein 73(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RAD18(gene name synonym) psi-mi:h2a1b_human(display_long)|uniprotkb:H2AC4(gene name)|psi-mi:H2AC4(display_short)|uniprotkb:H2AC8(gene name)|psi-mi:H2AC8(display_short)|uniprotkb:H2AFA(gene name synonym)|uniprotkb:H2AFM(gene name synonym)|uniprotkb:HIST1H2AB(gene name synonym)|uniprotkb:HIST1H2AE(gene name synonym)|uniprotkb:Histone H2A.2(gene name synonym)|uniprotkb:Histone H2A/a(gene name synonym)|uniprotkb:Histone H2A/m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483418|imex:IM-26985-567 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064550.3|ensembl:ENSP00000264926|dip:DIP-29831N|ensembl:ENSG00000070950(gene)|ensembl:ENST00000264926(transcript)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097505"(Rad6-Rad18 complex)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR006642(Zinc finger, Rad18-type putative)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036361|interpro:IPR039577|mint:Q9NS91|rcsb pdb:2MRE|rcsb pdb:2MRF|rcsb pdb:2Y43|rcsb pdb:2YBF|rcsb pdb:5VF0|reactome:R-HSA-110314|reactome:R-HSA-8866654|go:"GO:0060548"(negative regulation of cell death) refseq:NP_003504.2|refseq:NP_066390.1|ensembl:ENSG00000277075(gene)|ensembl:ENSG00000278463(gene)|ensembl:ENST00000303910(transcript)|ensembl:ENST00000615868(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P04908|rcsb pdb:2CV5|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1V|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACL|rcsb pdb:6AEE|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6KE9|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V92|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|rcsb pdb:6JXD|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|dip:DIP-44197N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/HmKCLqG1BxzmIWCgVpOw/gzJc49606 rogid:4Qno1mMYZB6FdNoojrzulWLVq849606 rigid:oEInMtJYUdA4a+eC72m+vRPn9w0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NS91 uniprotkb:P68363 intact:EBI-2339393|uniprotkb:Q9NRT6|uniprotkb:Q58F55|ensembl:ENSP00000264926 intact:EBI-487083|intact:EBI-1384226|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:Q27I68|ensembl:ENSP00000336799|uniprotkb:Q8WU19 psi-mi:rad18_human(display_long)|uniprotkb:RAD18(gene name)|psi-mi:RAD18(display_short)|uniprotkb:RNF73(gene name synonym)|uniprotkb:Postreplication repair protein RAD18(gene name synonym)|uniprotkb:RING finger protein 73(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RAD18(gene name synonym) psi-mi:tba1b_human(display_long)|uniprotkb:TUBA1B(gene name)|psi-mi:TUBA1B(display_short)|uniprotkb:Tubulin alpha-ubiquitous chain(gene name synonym)|uniprotkb:Alpha-tubulin ubiquitous(gene name synonym)|uniprotkb:Tubulin K-alpha-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483418|imex:IM-26985-567 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064550.3|ensembl:ENSP00000264926|dip:DIP-29831N|ensembl:ENSG00000070950(gene)|ensembl:ENST00000264926(transcript)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097505"(Rad6-Rad18 complex)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR006642(Zinc finger, Rad18-type putative)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036361|interpro:IPR039577|mint:Q9NS91|rcsb pdb:2MRE|rcsb pdb:2MRF|rcsb pdb:2Y43|rcsb pdb:2YBF|rcsb pdb:5VF0|reactome:R-HSA-110314|reactome:R-HSA-8866654|go:"GO:0060548"(negative regulation of cell death) refseq:NP_006073.2|ensembl:ENSG00000123416(gene)|ensembl:ENST00000336023(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-983189|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|go:"GO:0045121"(membrane raft)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68363|rcsb pdb:2E4H|rcsb pdb:5IJ0|rcsb pdb:5IJ9|rcsb pdb:5N5N|rcsb pdb:6E7B|rcsb pdb:6E7C|rcsb pdb:6I2I|go:"GO:0051301"(cell division)|rcsb pdb:6J4V|rcsb pdb:6J8O|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|rcsb pdb:6S8L|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9013407|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-2132295|reactome:R-HSA-9668328 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/HmKCLqG1BxzmIWCgVpOw/gzJc49606 rogid:D4YpuLCXl/S+53qV7P7sF81aARY9606 rigid:oEInMtJYUdA4a+eC72m+vRPn9w0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NS91 uniprotkb:P37108 intact:EBI-2339393|uniprotkb:Q9NRT6|uniprotkb:Q58F55|ensembl:ENSP00000264926 intact:EBI-353399|uniprotkb:Q6B0K5|intact:EBI-1053250|uniprotkb:Q96Q14|uniprotkb:B5BUF5|ensembl:ENSP00000267884 psi-mi:rad18_human(display_long)|uniprotkb:RAD18(gene name)|psi-mi:RAD18(display_short)|uniprotkb:RNF73(gene name synonym)|uniprotkb:Postreplication repair protein RAD18(gene name synonym)|uniprotkb:RING finger protein 73(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RAD18(gene name synonym) psi-mi:srp14_human(display_long)|uniprotkb:SRP14(gene name)|psi-mi:SRP14(display_short)|uniprotkb:18 kDa Alu RNA-binding protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483418|imex:IM-26985-567 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064550.3|ensembl:ENSP00000264926|dip:DIP-29831N|ensembl:ENSG00000070950(gene)|ensembl:ENST00000264926(transcript)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097505"(Rad6-Rad18 complex)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR006642(Zinc finger, Rad18-type putative)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036361|interpro:IPR039577|mint:Q9NS91|rcsb pdb:2MRE|rcsb pdb:2MRF|rcsb pdb:2Y43|rcsb pdb:2YBF|rcsb pdb:5VF0|reactome:R-HSA-110314|reactome:R-HSA-8866654|go:"GO:0060548"(negative regulation of cell death) refseq:NP_003125.3|dip:DIP-6152N|ensembl:ENSG00000140319(gene)|ensembl:ENST00000267884(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005786"(signal recognition particle, endoplasmic reticulum targeting)|go:"GO:0005829"(cytosol)|go:"GO:0006613"(cotranslational protein targeting to membrane)|go:"GO:0006614"(SRP-dependent cotranslational protein targeting to membrane)|go:"GO:0008312"(7S RNA binding)|go:"GO:0030942"(endoplasmic reticulum signal peptide binding)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045047"(protein targeting to ER)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR003210(Signal recognition particle, SRP14 subunit)|interpro:IPR009018(Signal recognition particle, SRP9/SRP14 subunit)|mint:P37108|rcsb pdb:1E8O|rcsb pdb:1E8S|rcsb pdb:1RY1|rcsb pdb:4UYJ|rcsb pdb:4UYK|rcsb pdb:5AOX|rcsb pdb:7NFX|reactome:R-HSA-1799339|reactome:R-HSA-6798695 - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/HmKCLqG1BxzmIWCgVpOw/gzJc49606 rogid:0xHelIgJbXaUrFsHGoj1wDQKdPs9606 rigid:oEInMtJYUdA4a+eC72m+vRPn9w0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NS91 uniprotkb:P0CG47 intact:EBI-2339393|uniprotkb:Q9NRT6|uniprotkb:Q58F55|ensembl:ENSP00000264926 intact:EBI-413034|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:Q29120|uniprotkb:Q6LBL4|uniprotkb:Q6LDU5|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9BWD6|uniprotkb:Q9BX98|uniprotkb:Q9UEF2|uniprotkb:Q9UEG1|uniprotkb:Q9UEK8|uniprotkb:Q9UPK7|uniprotkb:P62988|ensembl:ENSP00000304697|ensembl:ENSP00000379178|ensembl:ENSP00000379180|ensembl:ENSP00000478771 psi-mi:rad18_human(display_long)|uniprotkb:RAD18(gene name)|psi-mi:RAD18(display_short)|uniprotkb:RNF73(gene name synonym)|uniprotkb:Postreplication repair protein RAD18(gene name synonym)|uniprotkb:RING finger protein 73(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RAD18(gene name synonym) psi-mi:ubb_human(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483418|imex:IM-26985-567 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064550.3|ensembl:ENSP00000264926|dip:DIP-29831N|ensembl:ENSG00000070950(gene)|ensembl:ENST00000264926(transcript)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097505"(Rad6-Rad18 complex)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR006642(Zinc finger, Rad18-type putative)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036361|interpro:IPR039577|mint:Q9NS91|rcsb pdb:2MRE|rcsb pdb:2MRF|rcsb pdb:2Y43|rcsb pdb:2YBF|rcsb pdb:5VF0|reactome:R-HSA-110314|reactome:R-HSA-8866654|go:"GO:0060548"(negative regulation of cell death) refseq:NP_061828.1|refseq:NP_001268645.1|refseq:NP_001268646.1|refseq:NP_001268647.1|refseq:NP_001268648.1|refseq:NP_001268649.1|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG47|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060613"(fat pad development)|rcsb pdb:2KHW|rcsb pdb:2MBB|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:2MRO|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|rcsb pdb:2MSG|go:"GO:1901214"(regulation of neuron death)|rcsb pdb:2N13|rcsb pdb:4UEL|rcsb pdb:4UF6|rcsb pdb:4WHV|rcsb pdb:4WLR|rcsb pdb:4WUR|rcsb pdb:4XOF|rcsb pdb:4ZFR|rcsb pdb:4ZFT|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|rcsb pdb:4ZPZ|rcsb pdb:4ZUX|rcsb pdb:5BNB|rcsb pdb:5CAW|rcsb pdb:5CRA|rcsb pdb:5CVM|rcsb pdb:5CVN|rcsb pdb:5CVO|interpro:IPR000626(Ubiquitin)|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5DFL|rcsb pdb:5DK8|rcsb pdb:5E6J|rcsb pdb:5EDV|rcsb pdb:5EMZ|rcsb pdb:5EYA|rcsb pdb:5GJQ|rcsb pdb:5GO7|rcsb pdb:5GO8|rcsb pdb:5GOB|rcsb pdb:5GOC|rcsb pdb:5GOD|rcsb pdb:5GOG|rcsb pdb:5GOH|rcsb pdb:5GOI|rcsb pdb:5GOJ|rcsb pdb:5GOK|rcsb pdb:5H7S|rcsb pdb:5IBK|rcsb pdb:5IFR|rcsb pdb:5JBY|rcsb pdb:5JG6|rcsb pdb:5JP3|rcsb pdb:5JTJ|rcsb pdb:5JTV|rcsb pdb:5K9P|rcsb pdb:5KGF|rcsb pdb:5KHY|rcsb pdb:5KYC|rcsb pdb:5KYD|rcsb pdb:5KYE|rcsb pdb:5KYF|rcsb pdb:5L8H|rcsb pdb:5L8W|rcsb pdb:5L9T|rcsb pdb:5LN1|rcsb pdb:5LRV|rcsb pdb:5LRW|rcsb pdb:5LRX|rcsb pdb:5M93|rcsb pdb:5MNJ|rcsb pdb:5N2W|rcsb pdb:5N38|rcsb pdb:5NL5|rcsb pdb:5NLJ|rcsb pdb:5NVG|rcsb pdb:5O44|rcsb pdb:5O6T|rcsb pdb:5OHK|rcsb pdb:5OHL|rcsb pdb:5OHN|rcsb pdb:5OHP|rcsb pdb:5TOF|rcsb pdb:5TOG|rcsb pdb:5TUT|rcsb pdb:5TXK|rcsb pdb:5UJL|rcsb pdb:5UJN|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5V1Y|rcsb pdb:5V1Z|rcsb pdb:5VEY|rcsb pdb:5VF0|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5VZM|rcsb pdb:5VZW|rcsb pdb:5W46|rcsb pdb:5WFI|rcsb pdb:5X3M|rcsb pdb:5X3N|rcsb pdb:5X3O|rcsb pdb:5XBO|rcsb pdb:5XDP|rcsb pdb:5XK4|rcsb pdb:5XK5|rcsb pdb:5XPK|rcsb pdb:5YDR|rcsb pdb:5YIJ|rcsb pdb:5YIK|rcsb pdb:5YMY|rcsb pdb:5YT6|rcsb pdb:5ZBU|rcsb pdb:5ZD0|rcsb pdb:6ASR|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6CP2|rcsb pdb:6DGF|rcsb pdb:6EI1|rcsb pdb:6FDK|rcsb pdb:6FGE|rcsb pdb:6FTX|rcsb pdb:6FX4|rcsb pdb:6FYH|rcsb pdb:6GLC|rcsb pdb:6GZS|rcsb pdb:6H4H|rcsb pdb:6HEI|rcsb pdb:6HEK|rcsb pdb:6IF1|rcsb pdb:6ISU|rcsb pdb:6JB6|rcsb pdb:6JB7|rcsb pdb:6JMA|rcsb pdb:6K4I|rcsb pdb:6K9P|rcsb pdb:6KOW|rcsb pdb:6KOX|rcsb pdb:6LP2|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6N13|rcsb pdb:6NJ9|rcsb pdb:6NJG|rcsb pdb:6O96|rcsb pdb:6OAM|rcsb pdb:6PGV|rcsb pdb:6PZV|rcsb pdb:6QF8|rcsb pdb:6QK9|rcsb pdb:6QML|rcsb pdb:6TBM|rcsb pdb:6UH5|rcsb pdb:6XAA|rcsb pdb:7AY2|rcsb pdb:7BBD|rcsb pdb:7CAP|rcsb pdb:7JMS|rcsb pdb:7LYC|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|reactome:R-HSA-1253288|reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-162588|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-168928|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174184|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-211733|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2173788|reactome:R-HSA-2173791|reactome:R-HSA-174178|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2467813|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-349425|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69231|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-983168|reactome:R-HSA-8852276|reactome:R-HSA-8941858|reactome:R-HSA-8854050|reactome:R-HSA-8856825|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-8856828|reactome:R-HSA-8951664|reactome:R-HSA-8863795|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9683683|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-975163|reactome:R-HSA-977225|ensembl:ENSG00000170315(gene)|ensembl:ENST00000302182(transcript)|ensembl:ENST00000395837(transcript)|ensembl:ENST00000395839(transcript)|ensembl:ENST00000614404(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031386"(protein tag)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body) - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/HmKCLqG1BxzmIWCgVpOw/gzJc49606 rogid:X2Y1hzv2uGZd9FObQD2Qq3SECRo9606 rigid:oEInMtJYUdA4a+eC72m+vRPn9w0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NS91 uniprotkb:Q8IX21 intact:EBI-2339393|uniprotkb:Q9NRT6|uniprotkb:Q58F55|ensembl:ENSP00000264926 intact:EBI-2682240|uniprotkb:Q9NPE8|uniprotkb:A8K950|uniprotkb:Q5W0L8|uniprotkb:B1AL17|ensembl:ENSP00000238961|uniprotkb:Q6GMU6 psi-mi:rad18_human(display_long)|uniprotkb:RAD18(gene name)|psi-mi:RAD18(display_short)|uniprotkb:RNF73(gene name synonym)|uniprotkb:Postreplication repair protein RAD18(gene name synonym)|uniprotkb:RING finger protein 73(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RAD18(gene name synonym) psi-mi:slf2_human(display_long)|uniprotkb:SLF2(gene name)|psi-mi:SLF2(display_short)|uniprotkb:C10orf6(gene name synonym)|uniprotkb:FAM178A(gene name synonym)|uniprotkb:Smc5/6 localization factor 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483418|imex:IM-26985-567 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064550.3|ensembl:ENSP00000264926|dip:DIP-29831N|ensembl:ENSG00000070950(gene)|ensembl:ENST00000264926(transcript)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097505"(Rad6-Rad18 complex)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR006642(Zinc finger, Rad18-type putative)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036361|interpro:IPR039577|mint:Q9NS91|rcsb pdb:2MRE|rcsb pdb:2MRF|rcsb pdb:2Y43|rcsb pdb:2YBF|rcsb pdb:5VF0|reactome:R-HSA-110314|reactome:R-HSA-8866654|go:"GO:0060548"(negative regulation of cell death) refseq:NP_060591.3|refseq:NP_001230699.1|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR026161|interpro:IPR044276|mint:Q8IX21|ensembl:ENSG00000119906(gene)|ensembl:ENST00000238961(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034184"(positive regulation of maintenance of mitotic sister chromatid cohesion)|go:"GO:0035861"(site of double-strand break)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1990166"(protein localization to site of double-strand break)|refseq:NP_001129595.1 - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/HmKCLqG1BxzmIWCgVpOw/gzJc49606 rogid:Rf8vnUtDelcFN0qcbmtvHWn2z0c9606 rigid:oEInMtJYUdA4a+eC72m+vRPn9w0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NS91 uniprotkb:P35030 intact:EBI-2339393|uniprotkb:Q9NRT6|uniprotkb:Q58F55|ensembl:ENSP00000264926 intact:EBI-1221209|uniprotkb:Q5VXV0|intact:EBI-2825937|uniprotkb:A8CED3|uniprotkb:F8W7P3|uniprotkb:Q6ISJ4|uniprotkb:P15951|uniprotkb:Q15665|uniprotkb:Q9UQV3|uniprotkb:A9Z1Y4|uniprotkb:E7ES07|uniprotkb:A8CED1 psi-mi:rad18_human(display_long)|uniprotkb:RAD18(gene name)|psi-mi:RAD18(display_short)|uniprotkb:RNF73(gene name synonym)|uniprotkb:Postreplication repair protein RAD18(gene name synonym)|uniprotkb:RING finger protein 73(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RAD18(gene name synonym) psi-mi:try3_human(display_long)|uniprotkb:PRSS3(gene name)|psi-mi:PRSS3(display_short)|uniprotkb:PRSS4(gene name synonym)|uniprotkb:TRY3(gene name synonym)|uniprotkb:TRY4(gene name synonym)|uniprotkb:Trypsin III(gene name synonym)|uniprotkb:Brain trypsinogen(gene name synonym)|uniprotkb:Mesotrypsinogen(gene name synonym)|uniprotkb:Trypsin IV(gene name synonym)|uniprotkb:Serine protease 3(gene name synonym)|uniprotkb:Serine protease 4(gene name synonym)|uniprotkb:Mesotrypsin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483418|imex:IM-26985-567 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064550.3|ensembl:ENSP00000264926|dip:DIP-29831N|ensembl:ENSG00000070950(gene)|ensembl:ENST00000264926(transcript)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097505"(Rad6-Rad18 complex)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR006642(Zinc finger, Rad18-type putative)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036361|interpro:IPR039577|mint:Q9NS91|rcsb pdb:2MRE|rcsb pdb:2MRF|rcsb pdb:2Y43|rcsb pdb:2YBF|rcsb pdb:5VF0|reactome:R-HSA-110314|reactome:R-HSA-8866654|go:"GO:0060548"(negative regulation of cell death) refseq:NP_002762.2|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|refseq:NP_001184026.2|refseq:NP_031369.2|refseq:NP_001184027.1|mint:P35030|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0007586"(digestion)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0031638"(zymogen activation)|go:"GO:0043542"(endothelial cell migration)|go:"GO:1904724"(tertiary granule lumen)|rcsb pdb:1H4W|rcsb pdb:2R9P|rcsb pdb:3L33|rcsb pdb:3L3T|rcsb pdb:3P92|rcsb pdb:3P95|rcsb pdb:4DG4|rcsb pdb:4U30|rcsb pdb:4U32|rcsb pdb:5C67|rcsb pdb:5JBT|rcsb pdb:5TP0|rcsb pdb:6BX8|rcsb pdb:6GFI|reactome:R-HSA-1462054|reactome:R-HSA-196741|reactome:R-HSA-6798695|reactome:R-HSA-6803157|interpro:IPR043504 - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/HmKCLqG1BxzmIWCgVpOw/gzJc49606 rogid:AEfz7orXeNoasizB5N76AkF4WMk9606 rigid:oEInMtJYUdA4a+eC72m+vRPn9w0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NS91 uniprotkb:Q16777 intact:EBI-2339393|uniprotkb:Q9NRT6|uniprotkb:Q58F55|ensembl:ENSP00000264926 intact:EBI-5325566|ensembl:ENSP00000332194|uniprotkb:Q6DRA7|uniprotkb:Q8IUE5 psi-mi:rad18_human(display_long)|uniprotkb:RAD18(gene name)|psi-mi:RAD18(display_short)|uniprotkb:RNF73(gene name synonym)|uniprotkb:Postreplication repair protein RAD18(gene name synonym)|uniprotkb:RING finger protein 73(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RAD18(gene name synonym) psi-mi:h2a2c_human(display_long)|uniprotkb:H2AC20(gene name)|psi-mi:H2AC20(display_short)|uniprotkb:H2A-clustered histone 20(gene name synonym)|uniprotkb:H2AFQ(gene name synonym)|uniprotkb:HIST2H2AC(gene name synonym)|uniprotkb:Histone H2A-GL101(gene name synonym)|uniprotkb:Histone H2A/q(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483418|imex:IM-26985-567 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064550.3|ensembl:ENSP00000264926|dip:DIP-29831N|ensembl:ENSG00000070950(gene)|ensembl:ENST00000264926(transcript)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097505"(Rad6-Rad18 complex)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR006642(Zinc finger, Rad18-type putative)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036361|interpro:IPR039577|mint:Q9NS91|rcsb pdb:2MRE|rcsb pdb:2MRF|rcsb pdb:2Y43|rcsb pdb:2YBF|rcsb pdb:5VF0|reactome:R-HSA-110314|reactome:R-HSA-8866654|go:"GO:0060548"(negative regulation of cell death) reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-5689603|ensembl:ENSG00000184260(gene)|ensembl:ENST00000331380(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:Q16777|rcsb pdb:6Y5E|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|refseq:NP_003508.1 - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/HmKCLqG1BxzmIWCgVpOw/gzJc49606 rogid:Wejrpp9wK3GvA4ahJDVyEH+cwlQ9606 rigid:oEInMtJYUdA4a+eC72m+vRPn9w0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NS91 uniprotkb:P68431 intact:EBI-2339393|uniprotkb:Q9NRT6|uniprotkb:Q58F55|ensembl:ENSP00000264926 intact:EBI-79722|ensembl:ENSP00000352252|ensembl:ENSP00000358160|ensembl:ENSP00000366999|ensembl:ENSP00000480826|ensembl:ENSP00000482271|ensembl:ENSP00000483283|ensembl:ENSP00000484095|ensembl:ENSP00000484638|ensembl:ENSP00000484658|ensembl:ENSP00000484841|ensembl:ENSP00000489282|intact:EBI-1560041|uniprotkb:A0PJT7|uniprotkb:P02295|uniprotkb:P02296|uniprotkb:P16106|uniprotkb:Q6ISV8|uniprotkb:Q6NWP8|uniprotkb:Q6NWP9|uniprotkb:Q6NXU4|uniprotkb:Q71DJ3|uniprotkb:Q93081|uniprotkb:A5PLR1 psi-mi:rad18_human(display_long)|uniprotkb:RAD18(gene name)|psi-mi:RAD18(display_short)|uniprotkb:RNF73(gene name synonym)|uniprotkb:Postreplication repair protein RAD18(gene name synonym)|uniprotkb:RING finger protein 73(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RAD18(gene name synonym) psi-mi:h31_human(display_long)|uniprotkb:H3FA(gene name synonym)|uniprotkb:H3FL(gene name synonym)|uniprotkb:H3FD(gene name synonym)|uniprotkb:H3FI(gene name synonym)|uniprotkb:H3FH(gene name synonym)|uniprotkb:H3FK(gene name synonym)|uniprotkb:H3FF(gene name synonym)|uniprotkb:H3FJ(gene name synonym)|uniprotkb:H3FB(gene name synonym)|uniprotkb:Histone H3/a(gene name synonym)|uniprotkb:Histone H3/b(gene name synonym)|uniprotkb:Histone H3/c(gene name synonym)|uniprotkb:Histone H3/d(gene name synonym)|uniprotkb:Histone H3/f(gene name synonym)|uniprotkb:Histone H3/h(gene name synonym)|uniprotkb:Histone H3/i(gene name synonym)|uniprotkb:Histone H3/j(gene name synonym)|uniprotkb:Histone H3/k(gene name synonym)|uniprotkb:Histone H3/l(gene name synonym)|uniprotkb:H3C1(gene name)|psi-mi:H3C1(display_short)|uniprotkb:HIST1H3A(gene name synonym)|uniprotkb:H3C2(gene name)|psi-mi:H3C2(display_short)|uniprotkb:HIST1H3B(gene name synonym)|uniprotkb:H3C3(gene name)|psi-mi:H3C3(display_short)|uniprotkb:H3FC HIST1H3C(gene name synonym)|uniprotkb:H3C4(gene name)|psi-mi:H3C4(display_short)|uniprotkb:HIST1H3D(gene name synonym)|uniprotkb:H3C6(gene name)|psi-mi:H3C6(display_short)|uniprotkb:HIST1H3E(gene name synonym)|uniprotkb:H3C7(gene name)|psi-mi:H3C7(display_short)|uniprotkb:HIST1H3F(gene name synonym)|uniprotkb:H3C8(gene name)|psi-mi:H3C8(display_short)|uniprotkb:HIST1H3G(gene name synonym)|uniprotkb:H3C10(gene name)|psi-mi:H3C10(display_short)|uniprotkb:HIST1H3H(gene name synonym)|uniprotkb:H3C11(gene name)|psi-mi:H3C11(display_short)|uniprotkb:HIST1H3I(gene name synonym)|uniprotkb:H3C12(gene name)|psi-mi:H3C12(display_short)|uniprotkb:HIST1H3J(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483418|imex:IM-26985-567 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064550.3|ensembl:ENSP00000264926|dip:DIP-29831N|ensembl:ENSG00000070950(gene)|ensembl:ENST00000264926(transcript)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097505"(Rad6-Rad18 complex)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR006642(Zinc finger, Rad18-type putative)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036361|interpro:IPR039577|mint:Q9NS91|rcsb pdb:2MRE|rcsb pdb:2MRF|rcsb pdb:2Y43|rcsb pdb:2YBF|rcsb pdb:5VF0|reactome:R-HSA-110314|reactome:R-HSA-8866654|go:"GO:0060548"(negative regulation of cell death) rcsb pdb:4TN7|rcsb pdb:4U68|rcsb pdb:4UP0|rcsb pdb:4UY4|rcsb pdb:4X3K|rcsb pdb:4Y6L|rcsb pdb:4YHP|rcsb pdb:4YHZ|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z0R|rcsb pdb:4Z2M|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:4QBS|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B31|rcsb pdb:5C11|rcsb pdb:5C13|rcsb pdb:5C3I|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5D6Y|rcsb pdb:5DAH|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5FFV|rcsb pdb:5GH9|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5H6Q|rcsb pdb:5H6R|rcsb pdb:5HJB|rcsb pdb:5HJC|rcsb pdb:5HJD|rcsb pdb:5HYN|rcsb pdb:5IQL|rcsb pdb:5J3V|rcsb pdb:5J9S|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5B2J|rcsb pdb:5JRG|rcsb pdb:5KJH|rcsb pdb:5KJI|rcsb pdb:5KKL|rcsb pdb:5LUG|rcsb pdb:5M5G|rcsb pdb:5MR8|rcsb pdb:5NNC|rcsb pdb:5OY3|rcsb pdb:5SVX|rcsb pdb:5SVY|rcsb pdb:5SZB|rcsb pdb:5SZC|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5T1G|rcsb pdb:5T1I|rcsb pdb:5T8R|rcsb pdb:5TBN|rcsb pdb:5TDR|rcsb pdb:5TDW|rcsb pdb:5U2J|rcsb pdb:5V21|rcsb pdb:5V22|rcsb pdb:5VA6|rcsb pdb:5VAB|rcsb pdb:5VGE|rcsb pdb:5VNB|rcsb pdb:5NND|rcsb pdb:5WLE|rcsb pdb:5WVO|rcsb pdb:5WXG|rcsb pdb:5WXH|rcsb pdb:5WYI|rcsb pdb:5X60|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5XFQ|rcsb pdb:5XFR|rcsb pdb:5XNV|rcsb pdb:5XTZ|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Y20|rcsb pdb:5Y2F|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:6AXJ|rcsb pdb:6AZE|rcsb pdb:6BHD|rcsb pdb:6BHE|rcsb pdb:6BHG|rcsb pdb:6BHH|rcsb pdb:6BHI|rcsb pdb:6D07|rcsb pdb:6D08|rcsb pdb:6E83|rcsb pdb:6E86|rcsb pdb:5WFC|rcsb pdb:6F6D|rcsb pdb:6HTS|rcsb pdb:6IEU|rcsb pdb:6IIS|rcsb pdb:6IIT|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6JXD|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6LS6|rcsb pdb:6LSD|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MIL|rcsb pdb:6MIM|rcsb pdb:6MIN|rcsb pdb:6MIO|rcsb pdb:6MIQ|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6HKT|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2H|rcsb pdb:6V2K|rcsb pdb:6V3N|rcsb pdb:6V41|rcsb pdb:6V92|rcsb pdb:6VIL|rcsb pdb:6WAV|rcsb pdb:6WW4|rcsb pdb:6YIF|rcsb pdb:6YIH|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:6R92|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7KLR|rcsb pdb:7LYC|reactome:R-HSA-1266695|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|ensembl:ENSG00000197153(gene)|ensembl:ENSG00000197409(gene)|ensembl:ENSG00000273983(gene)|ensembl:ENSG00000274750(gene)|ensembl:ENSG00000275379(gene)|ensembl:ENSG00000275714(gene)|ensembl:ENSG00000277775(gene)|ensembl:ENSG00000278828(gene)|ensembl:ENSG00000286522(gene)|ensembl:ENSG00000287080(gene)|ensembl:ENST00000356476(transcript)|ensembl:ENST00000359303(transcript)|ensembl:ENST00000369163(transcript)|ensembl:ENST00000612966(transcript)|ensembl:ENST00000613854(transcript)|ensembl:ENST00000614378(transcript)|ensembl:ENST00000614911(transcript)|ensembl:ENST00000616365(transcript)|ensembl:ENST00000618052(transcript)|ensembl:ENST00000621411(transcript)|ensembl:ENST00000634733(transcript)|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-3247509|reactome:R-HSA-9710421|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060968"(obsolete regulation of gene silencing)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|interpro:IPR009072(Histone-fold)|mint:P68431|rcsb pdb:1CS9|rcsb pdb:1CT6|rcsb pdb:1O9S|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|rcsb pdb:1Q3L|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|rcsb pdb:2B2T|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|rcsb pdb:2B2U|rcsb pdb:2B2V|rcsb pdb:2B2W|rcsb pdb:2C1J|rcsb pdb:2C1N|go:"GO:0016020"(membrane)|rcsb pdb:2CO0|rcsb pdb:2CV5|rcsb pdb:2FSA|rcsb pdb:2KWJ|rcsb pdb:2KWK|rcsb pdb:2L75|rcsb pdb:2LBM|rcsb pdb:2LGG|rcsb pdb:2M0O|reactome:R-HSA-983231|reactome:R-HSA-977225|rcsb pdb:2NDG|rcsb pdb:2OQ6|rcsb pdb:2OT7|rcsb pdb:2OX0|rcsb pdb:2RI7|rcsb pdb:2RR4|rcsb pdb:2UXN|rcsb pdb:2V85|rcsb pdb:2V89|rcsb pdb:2VNF|rcsb pdb:2VPG|rcsb pdb:2X0L|rcsb pdb:3A1B|rcsb pdb:2NDF|rcsb pdb:3AFA|rcsb pdb:3AVR|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3B95|rcsb pdb:3FDT|rcsb pdb:3KMT|rcsb pdb:3KQI|rcsb pdb:3LQI|rcsb pdb:3LQJ|rcsb pdb:3MP1|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O37|rcsb pdb:3QJ6|rcsb pdb:3RIG|rcsb pdb:3RIY|rcsb pdb:3SOU|rcsb pdb:3SOW|rcsb pdb:3U31|rcsb pdb:3U3D|rcsb pdb:3U4S|rcsb pdb:3U5N|rcsb pdb:3U5O|rcsb pdb:3AZK|rcsb pdb:3U5P|rcsb pdb:3UEE|rcsb pdb:3UEF|rcsb pdb:3UII|rcsb pdb:3UIK|rcsb pdb:3V43|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:3ZG6|rcsb pdb:3ZVY|rcsb pdb:4A0J|rcsb pdb:4A0N|rcsb pdb:4A7J|rcsb pdb:3UIG|rcsb pdb:4BD3|rcsb pdb:4C1Q|rcsb pdb:4F4U|rcsb pdb:4F56|rcsb pdb:4FWF|rcsb pdb:4HON|rcsb pdb:4I51|rcsb pdb:4L7X|rcsb pdb:4LK9|rcsb pdb:4LKA|rcsb pdb:4LLB|rcsb pdb:4LXL|rcsb pdb:4N4H|rcsb pdb:4QBQ|rcsb pdb:4QBR|refseq:NP_003520.1|refseq:NP_003521.2|refseq:NP_003522.1|refseq:NP_003523.1|refseq:NP_003524.1|refseq:NP_003525.1|refseq:NP_003526.1|refseq:NP_003527.1|refseq:NP_003528.1|refseq:NP_066298.1|dip:DIP-29371N - - comment:"author score: 31" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/HmKCLqG1BxzmIWCgVpOw/gzJc49606 rogid:ood0OohxZHuhsWZtO7U7GMc+LwM9606 rigid:oEInMtJYUdA4a+eC72m+vRPn9w0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NS91 uniprotkb:Q9BQI6 intact:EBI-2339393|uniprotkb:Q9NRT6|uniprotkb:Q58F55|ensembl:ENSP00000264926 intact:EBI-10975834|ensembl:ENSP00000265140|uniprotkb:Q6NSA5|uniprotkb:Q9Y402|uniprotkb:B4DMG4|uniprotkb:Q3B7K4|uniprotkb:Q6PHW9 psi-mi:rad18_human(display_long)|uniprotkb:RAD18(gene name)|psi-mi:RAD18(display_short)|uniprotkb:RNF73(gene name synonym)|uniprotkb:Postreplication repair protein RAD18(gene name synonym)|uniprotkb:RING finger protein 73(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RAD18(gene name synonym) psi-mi:slf1_human(display_long)|uniprotkb:SLF1(gene name)|psi-mi:SLF1(display_short)|uniprotkb:ANKRD32(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 32(gene name synonym)|uniprotkb:BRCT domain-containing protein 1(gene name synonym)|uniprotkb:BRCTD1(gene name synonym)|uniprotkb:Smc5/6 localization factor 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483418|imex:IM-26985-567 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064550.3|ensembl:ENSP00000264926|dip:DIP-29831N|ensembl:ENSG00000070950(gene)|ensembl:ENST00000264926(transcript)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097505"(Rad6-Rad18 complex)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR006642(Zinc finger, Rad18-type putative)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036361|interpro:IPR039577|mint:Q9NS91|rcsb pdb:2MRE|rcsb pdb:2MRF|rcsb pdb:2Y43|rcsb pdb:2YBF|rcsb pdb:5VF0|reactome:R-HSA-110314|reactome:R-HSA-8866654|go:"GO:0060548"(negative regulation of cell death) refseq:NP_115666.2|ensembl:ENSG00000133302(gene)|ensembl:ENST00000265140(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034184"(positive regulation of maintenance of mitotic sister chromatid cohesion)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:1990166"(protein localization to site of double-strand break)|go:"GO:2000781"(positive regulation of double-strand break repair)|interpro:IPR001357(BRCT)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036420|interpro:IPR036770|interpro:IPR042479|mint:Q9BQI6|refseq:XP_016865468.1 - - comment:"author score: 37" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/HmKCLqG1BxzmIWCgVpOw/gzJc49606 rogid:qTH92h5XTeqL88TWZA5pSxkLFIg9606 rigid:oEInMtJYUdA4a+eC72m+vRPn9w0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NS91 uniprotkb:Q71DI3 intact:EBI-2339393|uniprotkb:Q9NRT6|uniprotkb:Q58F55|ensembl:ENSP00000264926 intact:EBI-750650|uniprotkb:A2BDF6|uniprotkb:A6NFS4|uniprotkb:Q6B053|ensembl:ENSP00000333277|ensembl:ENSP00000358154|ensembl:ENSP00000385479 psi-mi:rad18_human(display_long)|uniprotkb:RAD18(gene name)|psi-mi:RAD18(display_short)|uniprotkb:RNF73(gene name synonym)|uniprotkb:Postreplication repair protein RAD18(gene name synonym)|uniprotkb:RING finger protein 73(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RAD18(gene name synonym) psi-mi:h32_human(display_long)|uniprotkb:H3C13(gene name)|psi-mi:H3C13(display_short)|uniprotkb:H3C14(gene name)|psi-mi:H3C14(display_short)|uniprotkb:H3C15(gene name)|psi-mi:H3C15(display_short)|uniprotkb:H3-clustered histone 13(gene name synonym)|uniprotkb:H3-clustered histone 14(gene name synonym)|uniprotkb:H3-clustered histone 15(gene name synonym)|uniprotkb:H3F2(gene name synonym)|uniprotkb:H3FM(gene name synonym)|uniprotkb:HIST2H3A(gene name synonym)|uniprotkb:HIST2H3C(gene name synonym)|uniprotkb:HIST2H3D(gene name synonym)|uniprotkb:Histone H3/m(gene name synonym)|uniprotkb:Histone H3/o(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483418|imex:IM-26985-567 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064550.3|ensembl:ENSP00000264926|dip:DIP-29831N|ensembl:ENSG00000070950(gene)|ensembl:ENST00000264926(transcript)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097505"(Rad6-Rad18 complex)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR006642(Zinc finger, Rad18-type putative)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036361|interpro:IPR039577|mint:Q9NS91|rcsb pdb:2MRE|rcsb pdb:2MRF|rcsb pdb:2Y43|rcsb pdb:2YBF|rcsb pdb:5VF0|reactome:R-HSA-110314|reactome:R-HSA-8866654|go:"GO:0060548"(negative regulation of cell death) refseq:NP_001005464.1|refseq:NP_001116847.1|refseq:NP_066403.2|dip:DIP-48606N|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|rcsb pdb:7BU9|rcsb pdb:7JO9|rcsb pdb:7JOA|reactome:R-HSA-3214858|reactome:R-HSA-3247509|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-983231|rcsb pdb:7JZV|reactome:R-HSA-1266695|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|ensembl:ENSG00000183598(gene)|ensembl:ENSG00000203811(gene)|ensembl:ENSG00000203852(gene)|ensembl:ENST00000331491(transcript)|ensembl:ENST00000369158(transcript)|ensembl:ENST00000403683(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:Q71DI3|rcsb pdb:2IIJ|rcsb pdb:2X4W|rcsb pdb:2X4X|rcsb pdb:2X4Y|rcsb pdb:3AV1|rcsb pdb:3DB3|rcsb pdb:3MO8|rcsb pdb:3QO2|rcsb pdb:3R93|rcsb pdb:4MZF|rcsb pdb:4MZG|rcsb pdb:4MZH|rcsb pdb:4OUC|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B40|rcsb pdb:5BO0|rcsb pdb:5CIU|rcsb pdb:5VAC|rcsb pdb:6ACE|rcsb pdb:6FML|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6Y5E|rcsb pdb:7BQZ - - comment:"author score: 42" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/HmKCLqG1BxzmIWCgVpOw/gzJc49606 rogid:2TuVqWkeAnhHR4nrl0GNyUj1N3o9606 rigid:oEInMtJYUdA4a+eC72m+vRPn9w0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NS91 uniprotkb:P49459 intact:EBI-2339393|uniprotkb:Q9NRT6|uniprotkb:Q58F55|ensembl:ENSP00000264926 intact:EBI-2339348|uniprotkb:A6NMF5|uniprotkb:Q96FX4|uniprotkb:B2R7R9|uniprotkb:Q4TTG1|uniprotkb:D3DWI1|uniprotkb:A6NFE9|uniprotkb:A6NGR2|ensembl:ENSP00000360613 psi-mi:rad18_human(display_long)|uniprotkb:RAD18(gene name)|psi-mi:RAD18(display_short)|uniprotkb:RNF73(gene name synonym)|uniprotkb:Postreplication repair protein RAD18(gene name synonym)|uniprotkb:RING finger protein 73(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RAD18(gene name synonym) psi-mi:ube2a_human(display_long)|uniprotkb:UBE2A(gene name)|psi-mi:UBE2A(display_short)|uniprotkb:RAD6A(gene name synonym)|uniprotkb:Ubiquitin-protein ligase A(gene name synonym)|uniprotkb:Ubiquitin carrier protein A(gene name synonym)|uniprotkb:RAD6 homolog A(gene name synonym)|uniprotkb:E2 ubiquitin-conjugating enzyme A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483418|imex:IM-26985-567 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064550.3|ensembl:ENSP00000264926|dip:DIP-29831N|ensembl:ENSG00000070950(gene)|ensembl:ENST00000264926(transcript)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006281"(DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0051984"(positive regulation of chromosome segregation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097505"(Rad6-Rad18 complex)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR006642(Zinc finger, Rad18-type putative)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR036361|interpro:IPR039577|mint:Q9NS91|rcsb pdb:2MRE|rcsb pdb:2MRF|rcsb pdb:2Y43|rcsb pdb:2YBF|rcsb pdb:5VF0|reactome:R-HSA-110314|reactome:R-HSA-8866654|go:"GO:0060548"(negative regulation of cell death) refseq:NP_003327.2|refseq:NP_861427.1|refseq:NP_001269090.1|dip:DIP-24260N|ensembl:ENSG00000077721(gene)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000785"(chromatin)|go:"GO:0001741"(XY body)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009411"(response to UV)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033503"(HULC complex)|go:"GO:0033522"(histone H2A ubiquitination)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0070979"(protein K11-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR023313|mint:P49459|rcsb pdb:6CYO|rcsb pdb:6CYR|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-983168|ensembl:ENST00000371558(transcript) - - comment:"author score: 101" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/HmKCLqG1BxzmIWCgVpOw/gzJc49606 rogid:T6Mzgy6RHO9HoEIG3FmQvsP32vU9606 rigid:oEInMtJYUdA4a+eC72m+vRPn9w0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:P16104 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-494830|uniprotkb:Q4ZGJ7|uniprotkb:Q6IAS5|ensembl:ENSP00000364310|ensembl:ENSP00000434024 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:h2ax_human(display_long)|uniprotkb:H2AX(gene name)|psi-mi:H2AX(display_short)|uniprotkb:H2AFX(gene name synonym)|uniprotkb:Histone H2A.X(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483748|imex:IM-26985-429 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540 ensembl:ENSG00000188486(gene)|ensembl:ENST00000375167(transcript)|ensembl:ENST00000530167(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000786"(nucleosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|refseq:NP_002096.1|dip:DIP-33604N|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|go:"GO:0005813"(centrosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090398"(cellular senescence)|go:"GO:0090734"(site of DNA damage)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P16104|rcsb pdb:1YDP|rcsb pdb:2AZM|rcsb pdb:2D31|rcsb pdb:2DYP|rcsb pdb:3SHV|rcsb pdb:3SQD|rcsb pdb:3SZM|rcsb pdb:3U3Z|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:VQoEp3F8lEBTOj+PDDUzrJCQNZA9606 rigid:D4M1Xv2UNPFjRf5RmiDVfgL6GtY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:O95503 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-3951758|uniprotkb:A8KAH0|uniprotkb:Q96EM5|intact:EBI-28986885|ensembl:ENSP00000384490 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:cbx6_human(display_long)|uniprotkb:CBX6(gene name)|psi-mi:CBX6(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483748|imex:IM-26985-429 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540 refseq:NP_001290423.1|ensembl:ENSG00000183741(gene)|refseq:NP_055107.3|ensembl:ENST00000407418(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:O95503|rcsb pdb:3GV6|rcsb pdb:3I90|reactome:R-HSA-2559580|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSP00000384490|dip:DIP-48605N - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:4iNHCYe1bjb/JcurXP1iGoO/2uA9606 rigid:D4M1Xv2UNPFjRf5RmiDVfgL6GtY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:Q8NHM5 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-3955564|uniprotkb:Q1RLM7|uniprotkb:Q8NCI2|uniprotkb:Q96HC7|uniprotkb:Q96SL0|uniprotkb:Q96T03|uniprotkb:Q9NS96|uniprotkb:Q9UF75|ensembl:ENSP00000366271|uniprotkb:A8MRS1 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:kdm2b_human(display_long)|uniprotkb:KDM2B(gene name)|psi-mi:KDM2B(display_short)|uniprotkb:CXXC2(gene name synonym)|uniprotkb:FBL10(gene name synonym)|uniprotkb:FBXL10(gene name synonym)|uniprotkb:JHDM1B(gene name synonym)|uniprotkb:PCCX2(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 2(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 10(gene name synonym)|uniprotkb:F-box protein FBL10(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 10(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1B(gene name synonym)|uniprotkb:Jumonji domain-containing EMSY-interactor methyltransferase motif protein(gene name synonym)|uniprotkb:Protein-containing CXXC domain 2(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1B(gene name synonym)|uniprotkb:NDY1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483748|imex:IM-26985-429 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540 go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENST00000377071(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0021555"(midbrain-hindbrain boundary morphogenesis)|go:"GO:0021592"(fourth ventricle development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021678"(third ventricle development)|go:"GO:0021993"(initiation of neural tube closure)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|interpro:IPR041070|interpro:IPR041667|mint:Q8NHM5|rcsb pdb:4O64|rcsb pdb:5JH5|rcsb pdb:6BVA|reactome:R-HSA-3214842|refseq:NP_115979.3|ensembl:ENSG00000089094(gene)|refseq:NP_001005366.1 - - comment:"author score: 44" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:tnMbfP2oxwaaDyHHAigNt5hx4hM9606 rigid:D4M1Xv2UNPFjRf5RmiDVfgL6GtY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:P19784 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-347451|ensembl:ENSP00000262506 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:csk22_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)|uniprotkb:CK2A2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483748|imex:IM-26985-429 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540 refseq:NP_001887.1|dip:DIP-318N|ensembl:ENSG00000070770(gene)|ensembl:ENST00000262506(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19784|rcsb pdb:3E3B|rcsb pdb:3OFM|rcsb pdb:3U87|rcsb pdb:5M4U|rcsb pdb:5M56|rcsb pdb:5OOI|rcsb pdb:5Y9M|rcsb pdb:5YF9|rcsb pdb:5YWM|rcsb pdb:6HMB|rcsb pdb:6HMC|rcsb pdb:6HMD|rcsb pdb:6HMQ|rcsb pdb:6L20|rcsb pdb:6QY8|rcsb pdb:6QY9|rcsb pdb:6TE2|rcsb pdb:6TEW|rcsb pdb:6TGU|rcsb pdb:7A1B|rcsb pdb:7A1Z|rcsb pdb:7A22|rcsb pdb:7A2H|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:SIekW2yzNePP9hLKW7OHNFBwNck9606 rigid:D4M1Xv2UNPFjRf5RmiDVfgL6GtY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:Q14781 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-745934|uniprotkb:Q9BTB1|uniprotkb:Q0VDA5|ensembl:ENSP00000308750 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:cbx2_human(display_long)|uniprotkb:CBX2(gene name)|psi-mi:CBX2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483748|imex:IM-26985-429 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540 refseq:NP_005180.1|refseq:NP_116036.1|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|go:"GO:0045137"(development of primary sexual characteristics)|interpro:IPR042796|mint:Q14781|rcsb pdb:2D9U|rcsb pdb:3H91|rcsb pdb:5EPK|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSG00000173894(gene)|ensembl:ENST00000310942(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0030154"(cell differentiation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|dip:DIP-48604N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:220eC8UGlmAHHP2WAhZdAveHC3s9606 rigid:D4M1Xv2UNPFjRf5RmiDVfgL6GtY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:O00257 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483748|imex:IM-26985-429 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540 refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724 - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606 rigid:D4M1Xv2UNPFjRf5RmiDVfgL6GtY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:Q5H9F3 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-8833946|uniprotkb:Q5H9F4|uniprotkb:Q9Y528|uniprotkb:Q8TEN3|uniprotkb:B5MDQ8|uniprotkb:Q6ZVE0|uniprotkb:Q5H9F2|ensembl:ENSP00000218147|ensembl:ENSP00000437775 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:bcorl_human(display_long)|uniprotkb:BCORL1(gene name)|psi-mi:BCORL1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483748|imex:IM-26985-429 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540 ensembl:ENSP00000218147|ensembl:ENSP00000437775|refseq:NP_068765.3|dip:DIP-60148N|ensembl:ENSG00000085185(gene)|ensembl:ENST00000218147(transcript)|ensembl:ENST00000540052(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q5H9F3|rcsb pdb:4HPM|rcsb pdb:5JH5 - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:uQdpjjO3QnnX19nR1Ky76HjCdhw9606 rigid:D4M1Xv2UNPFjRf5RmiDVfgL6GtY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:Q96GD3 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-713793|uniprotkb:Q5VT76|uniprotkb:Q6IAJ4|uniprotkb:Q8WU48|uniprotkb:Q9UKM5|uniprotkb:Q9UKM6|ensembl:ENSP00000318094|ensembl:ENSP00000380359|uniprotkb:B4DRQ8 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:scmh1_human(display_long)|uniprotkb:Sex comb on midleg homolog 1(gene name synonym)|uniprotkb:SCMH1(gene name)|psi-mi:SCMH1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483748|imex:IM-26985-429 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540 refseq:XP_006710527.1|ensembl:ENSG00000010803(gene)|ensembl:ENST00000326197(transcript)|ensembl:ENST00000397174(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010369"(chromocenter)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|go:"GO:0005634"(nucleus)|interpro:IPR021987|interpro:IPR033763|interpro:IPR038348|mint:Q96GD3|rcsb pdb:2P0K|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|refseq:NP_001026864.1|refseq:NP_001165689.1|refseq:NP_001165690.1|refseq:NP_001165691.1|refseq:NP_001165692.1|refseq:NP_001165693.1|refseq:NP_036368.1|refseq:XP_016856188.1|refseq:XP_016856196.1|refseq:XP_011539335.1|refseq:XP_011539338.1 - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:e39O++wYwPAUlKUeNfRurqnXbz09606 rigid:D4M1Xv2UNPFjRf5RmiDVfgL6GtY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:P61964 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483748|imex:IM-26985-429 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540 refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N - - comment:"author score: 28" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rigid:D4M1Xv2UNPFjRf5RmiDVfgL6GtY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:P63208 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483748|imex:IM-26985-429 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540 reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N - - comment:"author score: 28" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rigid:D4M1Xv2UNPFjRf5RmiDVfgL6GtY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:Q8NDX5 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-1223801|uniprotkb:Q5HYF0|uniprotkb:Q6NSG2|uniprotkb:Q8NFT7|uniprotkb:Q8NFZ1|uniprotkb:Q8TBM2|uniprotkb:Q9H971|uniprotkb:Q9H9I4|uniprotkb:A2RRP9|ensembl:ENSP00000420271 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:phc3_human(display_long)|uniprotkb:PHC3(gene name)|psi-mi:PHC3(display_short)|uniprotkb:EDR3(gene name synonym)|uniprotkb:PH3(gene name synonym)|uniprotkb:Homolog of polyhomeotic 3(gene name synonym)|uniprotkb:Early development regulatory protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483748|imex:IM-26985-429 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540 refseq:NP_079223.3|refseq:NP_001295045.1|ensembl:ENSP00000420271|ensembl:ENST00000495893|ensembl:ENSP00000420294|ensembl:ENST00000497658|ensembl:ENSP00000420454|ensembl:ENSG00000173889(gene)|ensembl:ENST00000494943(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:Q8NDX5|rcsb pdb:4PZN|rcsb pdb:4PZO|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 - - comment:"author score: 30" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:hB1EMs+lCv19uuJ1O7+QiVCUoo89606 rigid:D4M1Xv2UNPFjRf5RmiDVfgL6GtY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:P78364 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-725403|uniprotkb:Q8WVM3|uniprotkb:Q9BU63|uniprotkb:D3DUV4|ensembl:ENSP00000437659|ensembl:ENSP00000440674 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:phc1_human(display_long)|uniprotkb:Early development regulatory protein 1(gene name synonym)|uniprotkb:PHC1(gene name)|psi-mi:PHC1(display_short)|uniprotkb:EDR1(gene name synonym)|uniprotkb:PH1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483748|imex:IM-26985-429 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540 refseq:NP_004417.2|ensembl:ENSG00000111752(gene)|ensembl:ENST00000543824(transcript)|ensembl:ENST00000544916(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:P78364|rcsb pdb:2L8E|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|dip:DIP-44567N - - comment:"author score: 31" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:0dDjrgvWcP5Sx8h+qUj7awuM3ko9606 rigid:D4M1Xv2UNPFjRf5RmiDVfgL6GtY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:Q8IXK0 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-713786|uniprotkb:Q8N306|uniprotkb:Q8TAG8|uniprotkb:A1L4Q1|uniprotkb:Q2TAL3|uniprotkb:Q5T0C1|uniprotkb:Q6NUJ6|uniprotkb:Q6ZQR1|uniprotkb:Q96BL4|uniprotkb:Q9Y4Y7|ensembl:ENSP00000257118|uniprotkb:D3DPR2|uniprotkb:A8KA40 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:phc2_human(display_long)|uniprotkb:Early development regulatory protein 2(gene name synonym)|uniprotkb:PHC2(gene name)|psi-mi:PHC2(display_short)|uniprotkb:EDR2(gene name synonym)|uniprotkb:PH2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483748|imex:IM-26985-429 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540 interpro:IPR038603|mint:Q8IXK0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR013761(Sterile alpha motif-type)|ensembl:ENSG00000134686(gene)|ensembl:ENST00000257118(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|refseq:NP_004418.2|refseq:NP_932157.1|refseq:XP_016856005.1|refseq:XP_016856006.1|refseq:XP_016856007.1|refseq:XP_005270627.1|dip:DIP-34464N - - comment:"author score: 39" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:7si/KU2tHoxviuCr70ncQERDWmY9606 rigid:D4M1Xv2UNPFjRf5RmiDVfgL6GtY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:Q8IWI9 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-2815196|uniprotkb:E7ENI0|uniprotkb:F5H7K2|uniprotkb:Q9H9N7|uniprotkb:Q9H8R3|uniprotkb:Q9Y4E9|uniprotkb:Q9UG69|intact:EBI-11143500|intact:EBI-10969960|ensembl:ENSP00000219905|uniprotkb:B9EGR5 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:mgap_human(display_long)|uniprotkb:MGA(gene name)|psi-mi:MGA(display_short)|uniprotkb:KIAA0518(gene name synonym)|uniprotkb:MAD5(gene name synonym)|uniprotkb:MAX dimerization protein 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483748|imex:IM-26985-429 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540 refseq:NP_001074010.2|ensembl:ENSP00000219905|ensembl:ENST00000566586|ensembl:ENSP00000456141|ensembl:ENSG00000174197(gene)|ensembl:ENST00000219905(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR018186|interpro:IPR032060|interpro:IPR036638|interpro:IPR036960|interpro:IPR037935|mint:Q8IWI9|reactome:R-HSA-8953750|refseq:NP_001157745.1|dip:DIP-57615N - - comment:"author score: 42" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:P4lo9EteCvikQQk5kyVkcobitLU9606 rigid:D4M1Xv2UNPFjRf5RmiDVfgL6GtY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:Q9HAH7 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-2847800|uniprotkb:Q9H9X4|uniprotkb:Q96CI9|uniprotkb:B4DP86|ensembl:ENSP00000287468 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:fbrs_human(display_long)|uniprotkb:FBRS(gene name)|psi-mi:FBRS(display_short)|uniprotkb:FBS(gene name synonym)|uniprotkb:FBS1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483748|imex:IM-26985-429 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540 refseq:NP_001098549.2|dip:DIP-61357N|ensembl:ENSG00000156860(gene)|ensembl:ENST00000287468(transcript)|interpro:IPR023246|mint:Q9HAH7 - - comment:"author score: 43" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:n1zkWAYdgwY+t7CFWg5RKO1VSfE9606 rigid:D4M1Xv2UNPFjRf5RmiDVfgL6GtY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:O75461 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483748|imex:IM-26985-429 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540 refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198 - - comment:"author score: 43" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rigid:D4M1Xv2UNPFjRf5RmiDVfgL6GtY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:Q13185 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483748|imex:IM-26985-429 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540 go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N - - comment:"author score: 43" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rigid:D4M1Xv2UNPFjRf5RmiDVfgL6GtY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:Q8IY57 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483748|imex:IM-26985-429 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540 refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N - - comment:"author score: 47" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 rigid:D4M1Xv2UNPFjRf5RmiDVfgL6GtY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:Q99496 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483748|imex:IM-26985-429 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540 refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 - - comment:"author score: 49" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rigid:D4M1Xv2UNPFjRf5RmiDVfgL6GtY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:Q6W2J9 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483748|imex:IM-26985-429 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540 ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N - - comment:"author score: 52" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rigid:D4M1Xv2UNPFjRf5RmiDVfgL6GtY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:Q969R5 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483748|imex:IM-26985-429 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540 refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750 - - comment:"author score: 52" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rigid:D4M1Xv2UNPFjRf5RmiDVfgL6GtY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:Q3KNV8 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-2339807|uniprotkb:O15262|uniprotkb:D3DVN1|ensembl:ENSP00000354724|ensembl:ENSP00000420489 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:pcgf3_human(display_long)|uniprotkb:PCGF3(gene name)|psi-mi:PCGF3(display_short)|uniprotkb:RNF3(gene name synonym)|uniprotkb:RNF3A(gene name synonym)|uniprotkb:RING finger protein 3A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483748|imex:IM-26985-429 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540 refseq:NP_006306.2|refseq:NP_001304765.1|dip:DIP-52782N|ensembl:ENSG00000185619(gene)|ensembl:ENST00000362003(transcript)|ensembl:ENST00000470161(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q3KNV8 - - comment:"author score: 53" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:Bt8LrtCWwivVQtfvjHQnhvrWli49606 rigid:D4M1Xv2UNPFjRf5RmiDVfgL6GtY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:Q86SE9 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500|ensembl:ENSP00000445704|ensembl:ENSP00000479492 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483748|imex:IM-26985-429 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540 refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSG00000180628(gene)|ensembl:ENST00000336126(transcript)|ensembl:ENST00000543648(transcript)|ensembl:ENST00000614189(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N - - comment:"author score: 63" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606 rigid:D4M1Xv2UNPFjRf5RmiDVfgL6GtY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:P35227 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-2129767|uniprotkb:A6NGD8|ensembl:ENSP00000478517|ensembl:ENSP00000478970|ensembl:ENSP00000482063|ensembl:ENSP00000482815|ensembl:ENSP00000488868|ensembl:ENSP00000488872 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:pcgf2_human(display_long)|uniprotkb:PCGF2(gene name)|psi-mi:PCGF2(display_short)|uniprotkb:MEL18(gene name synonym)|uniprotkb:RNF110(gene name synonym)|uniprotkb:ZNF144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483748|imex:IM-26985-429 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540 refseq:NP_009075.1|refseq:XP_016880505.1|refseq:XP_005257697.1|refseq:XP_005257698.1|refseq:XP_005257699.1|dip:DIP-41880N|ensembl:ENSG00000277258(gene)|ensembl:ENSG00000278644(gene)|ensembl:ENST00000610440(transcript)|ensembl:ENST00000611883(transcript)|ensembl:ENST00000616199(transcript)|ensembl:ENST00000620225(transcript)|ensembl:ENST00000631566(transcript)|ensembl:ENST00000631610(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35227|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-5617472|reactome:R-HSA-8953750 - - comment:"author score: 66" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:zppw56VrEl6gEFwtJMCN5cQkPxI9606 rigid:D4M1Xv2UNPFjRf5RmiDVfgL6GtY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:Q9BSM1 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483748|imex:IM-26985-429 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540 refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 - - comment:"author score: 68" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rigid:D4M1Xv2UNPFjRf5RmiDVfgL6GtY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:Q9HC52 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-712912|ensembl:ENSP00000269385|uniprotkb:Q96H39|uniprotkb:Q9NR07 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:cbx8_human(display_long)|uniprotkb:Polycomb 3 homolog(gene name synonym)|uniprotkb:Rectachrome 1(gene name synonym)|uniprotkb:CBX8(gene name)|psi-mi:CBX8(display_short)|uniprotkb:PC3(gene name synonym)|uniprotkb:RC1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483748|imex:IM-26985-429 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540 ensembl:ENSG00000141570(gene)|ensembl:ENST00000269385(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR000953(Chromo domain)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:Q9HC52|rcsb pdb:2N4Q|rcsb pdb:3I91|rcsb pdb:5EQ0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR016197(Chromo domain-like)|refseq:NP_065700.1|dip:DIP-44566N - - comment:"author score: 78" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:dAbuqieFRQ0DTC0fCAX9Jwe6EeU9606 rigid:D4M1Xv2UNPFjRf5RmiDVfgL6GtY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:Q9BYE7 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483748|imex:IM-26985-429 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540 refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N - - comment:"author score: 88" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 rigid:D4M1Xv2UNPFjRf5RmiDVfgL6GtY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:P35226 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-2341576|uniprotkb:Q5T8Z3|uniprotkb:Q96F37|uniprotkb:Q16030|intact:EBI-28989037|ensembl:ENSP00000365851 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:bmi1_human(display_long)|uniprotkb:BMI1(gene name)|psi-mi:BMI1(display_short)|uniprotkb:PCGF4(gene name synonym)|uniprotkb:RNF51(gene name synonym)|uniprotkb:Polycomb group RING finger protein 4(gene name synonym)|uniprotkb:RING finger protein 51(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483748|imex:IM-26985-429 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540 refseq:NP_001190991.1|refseq:NP_005171.4|ensembl:ENSP00000365851|dip:DIP-41879N|ensembl:ENSG00000168283(gene)|ensembl:ENST00000376663(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006959"(humoral immune response)|go:"GO:0007379"(segment specification)|go:"GO:0007420"(brain development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35226|rcsb pdb:2H0D|rcsb pdb:2NA1|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:5FR6|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 - - comment:"author score: 105" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:ruyez2gHfd/si8gxYUDZzZ1L4689606 rigid:D4M1Xv2UNPFjRf5RmiDVfgL6GtY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q06587 uniprotkb:Q8N488 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483748|imex:IM-26985-429 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540 refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity) - - comment:"author score: 139" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rigid:D4M1Xv2UNPFjRf5RmiDVfgL6GtY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:Q9HAH7 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-2847800|uniprotkb:Q9H9X4|uniprotkb:Q96CI9|uniprotkb:B4DP86|ensembl:ENSP00000287468 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:fbrs_human(display_long)|uniprotkb:FBRS(gene name)|psi-mi:FBRS(display_short)|uniprotkb:FBS(gene name synonym)|uniprotkb:FBS1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483841|imex:IM-26985-203 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 refseq:NP_001098549.2|dip:DIP-61357N|ensembl:ENSG00000156860(gene)|ensembl:ENST00000287468(transcript)|interpro:IPR023246|mint:Q9HAH7 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:n1zkWAYdgwY+t7CFWg5RKO1VSfE9606 rigid:SpcqsRVSW4hb//q8Lcw1OVx6cUI false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:Q14188 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-752268|uniprotkb:Q13331|uniprotkb:Q14187|uniprotkb:Q6R754|uniprotkb:Q8WU88|uniprotkb:F8WAI2|uniprotkb:Q9UG28|uniprotkb:D3DNG1|uniprotkb:B7Z8L5|uniprotkb:B7Z8C8|uniprotkb:E9PFC3|ensembl:ENSP00000420616 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:tfdp2_human(display_long)|uniprotkb:E2F dimerization partner 2(gene name synonym)|uniprotkb:TFDP2(gene name)|psi-mi:TFDP2(display_short)|uniprotkb:DP2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483841|imex:IM-26985-203 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 refseq:NP_001171609.1|refseq:NP_001171610.1|refseq:NP_006277.1|refseq:NP_001171612.1|refseq:NP_001171613.1|refseq:NP_001171611.1|refseq:XP_016862580.1|refseq:XP_016862585.1|refseq:XP_016862586.1|refseq:XP_016862587.1|refseq:XP_016862588.1|dip:DIP-294N|ensembl:ENSG00000114126(gene)|ensembl:ENST00000489671(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14188|rcsb pdb:1CF7|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9616222|reactome:R-HSA-9661069 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:Y+N26+kjBjMVwXdL4AEp0Sc1rYY9606 rigid:SpcqsRVSW4hb//q8Lcw1OVx6cUI false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:P63208 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483841|imex:IM-26985-203 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rigid:SpcqsRVSW4hb//q8Lcw1OVx6cUI false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:Q8IY57 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-2842031|uniprotkb:A8K5P0|uniprotkb:Q99710|uniprotkb:B4DFU3|uniprotkb:G3V465|ensembl:ENSP00000439256 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:yaf2_human(display_long)|uniprotkb:YAF2(gene name)|psi-mi:YAF2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483841|imex:IM-26985-203 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 refseq:NP_001177906.1|refseq:NP_001177908.1|refseq:NP_005739.2|refseq:NP_001177909.1|ensembl:ENSG00000015153(gene)|ensembl:ENST00000534854(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR038039|interpro:IPR039958|mint:Q8IY57|rcsb pdb:2D9G|reactome:R-HSA-8939243|reactome:R-HSA-8953750|dip:DIP-44919N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:x+0HcNK10qVfo3nfvTjMdF/zb649606 rigid:SpcqsRVSW4hb//q8Lcw1OVx6cUI false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:P61244 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483841|imex:IM-26985-203 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:I5d1d/zT353OsLios95yEITNoWU9606 rigid:SpcqsRVSW4hb//q8Lcw1OVx6cUI false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:Q5H9F3 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-8833946|uniprotkb:Q5H9F4|uniprotkb:Q9Y528|uniprotkb:Q8TEN3|uniprotkb:B5MDQ8|uniprotkb:Q6ZVE0|uniprotkb:Q5H9F2|ensembl:ENSP00000218147|ensembl:ENSP00000437775 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:bcorl_human(display_long)|uniprotkb:BCORL1(gene name)|psi-mi:BCORL1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483841|imex:IM-26985-203 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 ensembl:ENSP00000218147|ensembl:ENSP00000437775|refseq:NP_068765.3|dip:DIP-60148N|ensembl:ENSG00000085185(gene)|ensembl:ENST00000218147(transcript)|ensembl:ENST00000540052(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q5H9F3|rcsb pdb:4HPM|rcsb pdb:5JH5 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:uQdpjjO3QnnX19nR1Ky76HjCdhw9606 rigid:SpcqsRVSW4hb//q8Lcw1OVx6cUI false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:O75461 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483841|imex:IM-26985-203 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rigid:SpcqsRVSW4hb//q8Lcw1OVx6cUI false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:Q3KNV8 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-2339807|uniprotkb:O15262|uniprotkb:D3DVN1|ensembl:ENSP00000354724|ensembl:ENSP00000420489 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:pcgf3_human(display_long)|uniprotkb:PCGF3(gene name)|psi-mi:PCGF3(display_short)|uniprotkb:RNF3(gene name synonym)|uniprotkb:RNF3A(gene name synonym)|uniprotkb:RING finger protein 3A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483841|imex:IM-26985-203 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 refseq:NP_006306.2|refseq:NP_001304765.1|dip:DIP-52782N|ensembl:ENSG00000185619(gene)|ensembl:ENST00000362003(transcript)|ensembl:ENST00000470161(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q3KNV8 - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:Bt8LrtCWwivVQtfvjHQnhvrWli49606 rigid:SpcqsRVSW4hb//q8Lcw1OVx6cUI false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:Q14781 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-745934|uniprotkb:Q9BTB1|uniprotkb:Q0VDA5|ensembl:ENSP00000308750 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:cbx2_human(display_long)|uniprotkb:CBX2(gene name)|psi-mi:CBX2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483841|imex:IM-26985-203 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 refseq:NP_005180.1|refseq:NP_116036.1|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|go:"GO:0045137"(development of primary sexual characteristics)|interpro:IPR042796|mint:Q14781|rcsb pdb:2D9U|rcsb pdb:3H91|rcsb pdb:5EPK|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSG00000173894(gene)|ensembl:ENST00000310942(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0030154"(cell differentiation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|dip:DIP-48604N - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:220eC8UGlmAHHP2WAhZdAveHC3s9606 rigid:SpcqsRVSW4hb//q8Lcw1OVx6cUI false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:Q13185 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483841|imex:IM-26985-203 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rigid:SpcqsRVSW4hb//q8Lcw1OVx6cUI false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:Q86SE9 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500|ensembl:ENSP00000445704|ensembl:ENSP00000479492 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483841|imex:IM-26985-203 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSG00000180628(gene)|ensembl:ENST00000336126(transcript)|ensembl:ENST00000543648(transcript)|ensembl:ENST00000614189(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606 rigid:SpcqsRVSW4hb//q8Lcw1OVx6cUI false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:Q8IWI9 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-2815196|uniprotkb:E7ENI0|uniprotkb:F5H7K2|uniprotkb:Q9H9N7|uniprotkb:Q9H8R3|uniprotkb:Q9Y4E9|uniprotkb:Q9UG69|intact:EBI-11143500|intact:EBI-10969960|ensembl:ENSP00000219905|uniprotkb:B9EGR5 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:mgap_human(display_long)|uniprotkb:MGA(gene name)|psi-mi:MGA(display_short)|uniprotkb:KIAA0518(gene name synonym)|uniprotkb:MAD5(gene name synonym)|uniprotkb:MAX dimerization protein 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483841|imex:IM-26985-203 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 refseq:NP_001074010.2|ensembl:ENSP00000219905|ensembl:ENST00000566586|ensembl:ENSP00000456141|ensembl:ENSG00000174197(gene)|ensembl:ENST00000219905(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR018186|interpro:IPR032060|interpro:IPR036638|interpro:IPR036960|interpro:IPR037935|mint:Q8IWI9|reactome:R-HSA-8953750|refseq:NP_001157745.1|dip:DIP-57615N - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:P4lo9EteCvikQQk5kyVkcobitLU9606 rigid:SpcqsRVSW4hb//q8Lcw1OVx6cUI false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:P78364 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-725403|uniprotkb:Q8WVM3|uniprotkb:Q9BU63|uniprotkb:D3DUV4|ensembl:ENSP00000437659|ensembl:ENSP00000440674 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:phc1_human(display_long)|uniprotkb:Early development regulatory protein 1(gene name synonym)|uniprotkb:PHC1(gene name)|psi-mi:PHC1(display_short)|uniprotkb:EDR1(gene name synonym)|uniprotkb:PH1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483841|imex:IM-26985-203 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 refseq:NP_004417.2|ensembl:ENSG00000111752(gene)|ensembl:ENST00000543824(transcript)|ensembl:ENST00000544916(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:P78364|rcsb pdb:2L8E|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|dip:DIP-44567N - - comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:0dDjrgvWcP5Sx8h+qUj7awuM3ko9606 rigid:SpcqsRVSW4hb//q8Lcw1OVx6cUI false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:Q8NDX5 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-1223801|uniprotkb:Q5HYF0|uniprotkb:Q6NSG2|uniprotkb:Q8NFT7|uniprotkb:Q8NFZ1|uniprotkb:Q8TBM2|uniprotkb:Q9H971|uniprotkb:Q9H9I4|uniprotkb:A2RRP9|ensembl:ENSP00000420271 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:phc3_human(display_long)|uniprotkb:PHC3(gene name)|psi-mi:PHC3(display_short)|uniprotkb:EDR3(gene name synonym)|uniprotkb:PH3(gene name synonym)|uniprotkb:Homolog of polyhomeotic 3(gene name synonym)|uniprotkb:Early development regulatory protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483841|imex:IM-26985-203 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 refseq:NP_079223.3|refseq:NP_001295045.1|ensembl:ENSP00000420271|ensembl:ENST00000495893|ensembl:ENSP00000420294|ensembl:ENST00000497658|ensembl:ENSP00000420454|ensembl:ENSG00000173889(gene)|ensembl:ENST00000494943(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:Q8NDX5|rcsb pdb:4PZN|rcsb pdb:4PZO|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:hB1EMs+lCv19uuJ1O7+QiVCUoo89606 rigid:SpcqsRVSW4hb//q8Lcw1OVx6cUI false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:Q6W2J9 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483841|imex:IM-26985-203 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N - - comment:"author score: 29" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rigid:SpcqsRVSW4hb//q8Lcw1OVx6cUI false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:Q9BSM1 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483841|imex:IM-26985-203 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 - - comment:"author score: 31" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rigid:SpcqsRVSW4hb//q8Lcw1OVx6cUI false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:P35227 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-2129767|uniprotkb:A6NGD8|ensembl:ENSP00000478517|ensembl:ENSP00000478970|ensembl:ENSP00000482063|ensembl:ENSP00000482815|ensembl:ENSP00000488868|ensembl:ENSP00000488872 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:pcgf2_human(display_long)|uniprotkb:PCGF2(gene name)|psi-mi:PCGF2(display_short)|uniprotkb:MEL18(gene name synonym)|uniprotkb:RNF110(gene name synonym)|uniprotkb:ZNF144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483841|imex:IM-26985-203 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 refseq:NP_009075.1|refseq:XP_016880505.1|refseq:XP_005257697.1|refseq:XP_005257698.1|refseq:XP_005257699.1|dip:DIP-41880N|ensembl:ENSG00000277258(gene)|ensembl:ENSG00000278644(gene)|ensembl:ENST00000610440(transcript)|ensembl:ENST00000611883(transcript)|ensembl:ENST00000616199(transcript)|ensembl:ENST00000620225(transcript)|ensembl:ENST00000631566(transcript)|ensembl:ENST00000631610(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35227|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-5617472|reactome:R-HSA-8953750 - - comment:"author score: 32" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:zppw56VrEl6gEFwtJMCN5cQkPxI9606 rigid:SpcqsRVSW4hb//q8Lcw1OVx6cUI false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:Q8IXK0 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-713786|uniprotkb:Q8N306|uniprotkb:Q8TAG8|uniprotkb:A1L4Q1|uniprotkb:Q2TAL3|uniprotkb:Q5T0C1|uniprotkb:Q6NUJ6|uniprotkb:Q6ZQR1|uniprotkb:Q96BL4|uniprotkb:Q9Y4Y7|ensembl:ENSP00000257118|uniprotkb:D3DPR2|uniprotkb:A8KA40 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:phc2_human(display_long)|uniprotkb:Early development regulatory protein 2(gene name synonym)|uniprotkb:PHC2(gene name)|psi-mi:PHC2(display_short)|uniprotkb:EDR2(gene name synonym)|uniprotkb:PH2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483841|imex:IM-26985-203 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 interpro:IPR038603|mint:Q8IXK0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR013761(Sterile alpha motif-type)|ensembl:ENSG00000134686(gene)|ensembl:ENST00000257118(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|refseq:NP_004418.2|refseq:NP_932157.1|refseq:XP_016856005.1|refseq:XP_016856006.1|refseq:XP_016856007.1|refseq:XP_005270627.1|dip:DIP-34464N - - comment:"author score: 32" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:7si/KU2tHoxviuCr70ncQERDWmY9606 rigid:SpcqsRVSW4hb//q8Lcw1OVx6cUI false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:Q9BYE7 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483841|imex:IM-26985-203 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N - - comment:"author score: 38" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 rigid:SpcqsRVSW4hb//q8Lcw1OVx6cUI false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q99496 uniprotkb:P35226 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 intact:EBI-2341576|uniprotkb:Q5T8Z3|uniprotkb:Q96F37|uniprotkb:Q16030|intact:EBI-28989037|ensembl:ENSP00000365851 psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:bmi1_human(display_long)|uniprotkb:BMI1(gene name)|psi-mi:BMI1(display_short)|uniprotkb:PCGF4(gene name synonym)|uniprotkb:RNF51(gene name synonym)|uniprotkb:Polycomb group RING finger protein 4(gene name synonym)|uniprotkb:RING finger protein 51(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483841|imex:IM-26985-203 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 refseq:NP_001190991.1|refseq:NP_005171.4|ensembl:ENSP00000365851|dip:DIP-41879N|ensembl:ENSG00000168283(gene)|ensembl:ENST00000376663(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006959"(humoral immune response)|go:"GO:0007379"(segment specification)|go:"GO:0007420"(brain development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35226|rcsb pdb:2H0D|rcsb pdb:2NA1|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:5FR6|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 - - comment:"author score: 54" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rogid:ruyez2gHfd/si8gxYUDZzZ1L4689606 rigid:SpcqsRVSW4hb//q8Lcw1OVx6cUI false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969K3 uniprotkb:P63272 intact:EBI-2340642|uniprotkb:Q8NG47|uniprotkb:Q9H6W8|uniprotkb:B7Z933|ensembl:ENSP00000355137 intact:EBI-727250|uniprotkb:Q16550|uniprotkb:Q62387|uniprotkb:Q6ZP89|uniprotkb:B2R4X8|uniprotkb:D3DTZ4|ensembl:ENSP00000225504|ensembl:ENSP00000462670 psi-mi:rnf34_human(display_long)|uniprotkb:RNF34(gene name)|psi-mi:RNF34(display_short)|uniprotkb:RING finger protein 34(gene name synonym)|uniprotkb:RING finger protein RIFF(gene name synonym)|uniprotkb:FYVE-RING finger protein Momo(gene name synonym)|uniprotkb:Human RING finger homologous to inhibitor of apoptosis protein(gene name synonym)|uniprotkb:Caspases-8 and -10-associated RING finger protein 1(gene name synonym)|uniprotkb:Caspase regulator CARP1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF34(gene name synonym) psi-mi:spt4h_human(display_long)|uniprotkb:DRB sensitivity-inducing factor small subunit(gene name synonym)|uniprotkb:DRB sensitivity-inducing factor 14 kDa subunit(gene name synonym)|uniprotkb:SUPT4H1(gene name)|psi-mi:SUPT4H1(display_short)|uniprotkb:SPT4H(gene name synonym)|uniprotkb:SUPT4H(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483907|imex:IM-26985-431 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001243787.1|refseq:NP_079402.2|refseq:NP_919247.1|ensembl:ENSG00000170633(gene)|ensembl:ENST00000361234(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035872"(nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1901797"(negative regulation of signal transduction by p53 class mediator)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:2000374"(regulation of oxygen metabolic process)|go:"GO:2001271"(negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR036361|mint:Q969K3|reactome:R-HSA-6804757|reactome:R-HSA-983168 refseq:NP_003159.1|ensembl:ENSG00000213246(gene)|ensembl:ENST00000225504(transcript)|ensembl:ENST00000580947(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032785"(negative regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR009287(Transcription initiation Spt4)|interpro:IPR022800|interpro:IPR029040|interpro:IPR038510|mint:P63272|rcsb pdb:3H7H|rcsb pdb:5OIK|rcsb pdb:6GMH|rcsb pdb:6GML|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|dip:DIP-40644N - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pvINlXbJ9UfZbyW4YqRO+HQsCnw9606 rogid:dz+Mu8lTSRS/nIQ+RUKWIiJAwTE9606 rigid:VMIlUbljvn92BC6tgZjW0HYzqRw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969K3 uniprotkb:P54652 intact:EBI-2340642|uniprotkb:Q8NG47|uniprotkb:Q9H6W8|uniprotkb:B7Z933|ensembl:ENSP00000355137 intact:EBI-356991|uniprotkb:Q15508|uniprotkb:Q53XM3|uniprotkb:Q9UE78|ensembl:ENSP00000247207|ensembl:ENSP00000378199 psi-mi:rnf34_human(display_long)|uniprotkb:RNF34(gene name)|psi-mi:RNF34(display_short)|uniprotkb:RING finger protein 34(gene name synonym)|uniprotkb:RING finger protein RIFF(gene name synonym)|uniprotkb:FYVE-RING finger protein Momo(gene name synonym)|uniprotkb:Human RING finger homologous to inhibitor of apoptosis protein(gene name synonym)|uniprotkb:Caspases-8 and -10-associated RING finger protein 1(gene name synonym)|uniprotkb:Caspase regulator CARP1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF34(gene name synonym) psi-mi:hsp72_human(display_long)|uniprotkb:HSPA2(gene name)|psi-mi:HSPA2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483907|imex:IM-26985-431 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001243787.1|refseq:NP_079402.2|refseq:NP_919247.1|ensembl:ENSG00000170633(gene)|ensembl:ENST00000361234(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035872"(nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1901797"(negative regulation of signal transduction by p53 class mediator)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:2000374"(regulation of oxygen metabolic process)|go:"GO:2001271"(negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR036361|mint:Q969K3|reactome:R-HSA-6804757|reactome:R-HSA-983168 refseq:NP_068814.2|ensembl:ENSG00000126803(gene)|ensembl:ENST00000247207(transcript)|ensembl:ENST00000394709(transcript)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0009408"(response to heat)|go:"GO:0009409"(response to cold)|go:"GO:0009986"(cell surface)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019899"(enzyme binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0036128"(CatSper complex)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0048156"(tau protein binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0051861"(glycolipid binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0072562"(blood microparticle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901896"(positive regulation of ATPase-coupled calcium transmembrane transporter activity)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P54652|rcsb pdb:3I33|rcsb pdb:4FSV|rcsb pdb:5FPD|rcsb pdb:5FPE|rcsb pdb:5FPM|rcsb pdb:5FPN|reactome:R-HSA-1221632|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568 - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pvINlXbJ9UfZbyW4YqRO+HQsCnw9606 rogid:U+fdNfdxAWBQxDwSx0plk/iIBpM9606 rigid:VMIlUbljvn92BC6tgZjW0HYzqRw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969K3 uniprotkb:Q99417 intact:EBI-2340642|uniprotkb:Q8NG47|uniprotkb:Q9H6W8|uniprotkb:B7Z933|ensembl:ENSP00000355137 intact:EBI-716185|intact:EBI-2559925|uniprotkb:Q5TA64|uniprotkb:Q96HE2|uniprotkb:B2R4N0|ensembl:ENSP00000380702 psi-mi:rnf34_human(display_long)|uniprotkb:RNF34(gene name)|psi-mi:RNF34(display_short)|uniprotkb:RING finger protein 34(gene name synonym)|uniprotkb:RING finger protein RIFF(gene name synonym)|uniprotkb:FYVE-RING finger protein Momo(gene name synonym)|uniprotkb:Human RING finger homologous to inhibitor of apoptosis protein(gene name synonym)|uniprotkb:Caspases-8 and -10-associated RING finger protein 1(gene name synonym)|uniprotkb:Caspase regulator CARP1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF34(gene name synonym) psi-mi:mycbp_human(display_long)|uniprotkb:Associate of Myc 1(gene name synonym)|uniprotkb:MYCBP(gene name)|psi-mi:MYCBP(display_short)|uniprotkb:AMY1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483907|imex:IM-26985-431 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001243787.1|refseq:NP_079402.2|refseq:NP_919247.1|ensembl:ENSG00000170633(gene)|ensembl:ENST00000361234(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035872"(nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1901797"(negative regulation of signal transduction by p53 class mediator)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:2000374"(regulation of oxygen metabolic process)|go:"GO:2001271"(negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR036361|mint:Q969K3|reactome:R-HSA-6804757|reactome:R-HSA-983168 refseq:NP_036465.2|ensembl:ENSG00000214114(gene)|ensembl:ENST00000397572(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007283"(spermatogenesis)|interpro:IPR026060|mint:Q99417|rcsb pdb:2YY0 - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pvINlXbJ9UfZbyW4YqRO+HQsCnw9606 rogid:jIStn1A10DDkgTuwVeKpDPJ6tIs9606 rigid:VMIlUbljvn92BC6tgZjW0HYzqRw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969K3 uniprotkb:Q9Y6H1 intact:EBI-2340642|uniprotkb:Q8NG47|uniprotkb:Q9H6W8|uniprotkb:B7Z933|ensembl:ENSP00000355137 intact:EBI-2321769|uniprotkb:Q498C3|uniprotkb:Q6NZ50|ensembl:ENSP00000378812 psi-mi:rnf34_human(display_long)|uniprotkb:RNF34(gene name)|psi-mi:RNF34(display_short)|uniprotkb:RING finger protein 34(gene name synonym)|uniprotkb:RING finger protein RIFF(gene name synonym)|uniprotkb:FYVE-RING finger protein Momo(gene name synonym)|uniprotkb:Human RING finger homologous to inhibitor of apoptosis protein(gene name synonym)|uniprotkb:Caspases-8 and -10-associated RING finger protein 1(gene name synonym)|uniprotkb:Caspase regulator CARP1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF34(gene name synonym) psi-mi:chch2_human(display_long)|uniprotkb:CHCHD2(gene name)|psi-mi:CHCHD2(display_short)|uniprotkb:C7orf17(gene name synonym)|uniprotkb:HCV NS2 trans-regulated protein(gene name synonym)|uniprotkb:Aging-associated gene 10 protein(gene name synonym)|uniprotkb:AAG10(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483907|imex:IM-26985-431 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001243787.1|refseq:NP_079402.2|refseq:NP_919247.1|ensembl:ENSG00000170633(gene)|ensembl:ENST00000361234(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035872"(nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1901797"(negative regulation of signal transduction by p53 class mediator)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:2000374"(regulation of oxygen metabolic process)|go:"GO:2001271"(negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR036361|mint:Q969K3|reactome:R-HSA-6804757|reactome:R-HSA-983168 refseq:NP_057223.1|ensembl:ENSG00000106153(gene)|ensembl:ENST00000395422(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900037"(regulation of cellular response to hypoxia)|go:"GO:1905448"(positive regulation of mitochondrial ATP synthesis coupled electron transport)|interpro:IPR010625(CHCH)|mint:Q9Y6H1|reactome:R-HSA-1268020 - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pvINlXbJ9UfZbyW4YqRO+HQsCnw9606 rogid:fdx3lE51+yZ1k3uwh8/LDKJC+CQ9606 rigid:VMIlUbljvn92BC6tgZjW0HYzqRw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969K3 uniprotkb:O00267 intact:EBI-2340642|uniprotkb:Q8NG47|uniprotkb:Q9H6W8|uniprotkb:B7Z933|ensembl:ENSP00000355137 intact:EBI-710464|ensembl:ENSP00000404029|ensembl:ENSP00000469090|ensembl:ENSP00000470252|uniprotkb:O43279|uniprotkb:Q59G52|uniprotkb:Q99639 psi-mi:rnf34_human(display_long)|uniprotkb:RNF34(gene name)|psi-mi:RNF34(display_short)|uniprotkb:RING finger protein 34(gene name synonym)|uniprotkb:RING finger protein RIFF(gene name synonym)|uniprotkb:FYVE-RING finger protein Momo(gene name synonym)|uniprotkb:Human RING finger homologous to inhibitor of apoptosis protein(gene name synonym)|uniprotkb:Caspases-8 and -10-associated RING finger protein 1(gene name synonym)|uniprotkb:Caspase regulator CARP1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF34(gene name synonym) psi-mi:spt5h_human(display_long)|uniprotkb:DRB sensitivity-inducing factor large subunit(gene name synonym)|uniprotkb:DRB sensitivity-inducing factor 160 kDa subunit(gene name synonym)|uniprotkb:Tat-cotransactivator 1 protein(gene name synonym)|uniprotkb:SUPT5H(gene name)|psi-mi:SUPT5H(display_short)|uniprotkb:SPT5(gene name synonym)|uniprotkb:SPT5H(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483907|imex:IM-26985-431 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001243787.1|refseq:NP_079402.2|refseq:NP_919247.1|ensembl:ENSG00000170633(gene)|ensembl:ENST00000361234(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035872"(nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1901797"(negative regulation of signal transduction by p53 class mediator)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:2000374"(regulation of oxygen metabolic process)|go:"GO:2001271"(negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR036361|mint:Q969K3|reactome:R-HSA-6804757|reactome:R-HSA-983168 refseq:NP_001124296.1|refseq:NP_001124297.1|refseq:NP_003160.2|refseq:NP_001104490.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019899"(enzyme binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032785"(negative regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|ensembl:ENSG00000196235(gene)|ensembl:ENST00000432763(transcript)|ensembl:ENST00000598725(transcript)|ensembl:ENST00000599117(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|interpro:IPR041980|mint:O00267|rcsb pdb:2DO3|rcsb pdb:2E6Z|rcsb pdb:2E70|rcsb pdb:3H7H|rcsb pdb:4L1U|rcsb pdb:5OHO|rcsb pdb:5OHQ|rcsb pdb:5OIK|rcsb pdb:5U98|rcsb pdb:6EQY|rcsb pdb:6ER0|rcsb pdb:6GMH|rcsb pdb:6GML|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-75955|reactome:R-HSA-77075|refseq:NP_001306920.1|refseq:NP_001306919.1|dip:DIP-29014N - - comment:"author score: 40" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pvINlXbJ9UfZbyW4YqRO+HQsCnw9606 rogid:8VodOhZyrmNy3xxDTTsB8KugN849606 rigid:VMIlUbljvn92BC6tgZjW0HYzqRw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969K3 uniprotkb:P04083 intact:EBI-2340642|uniprotkb:Q8NG47|uniprotkb:Q9H6W8|uniprotkb:B7Z933|ensembl:ENSP00000355137 intact:EBI-354007|ensembl:ENSP00000257497|ensembl:ENSP00000366109|uniprotkb:B5BU38 psi-mi:rnf34_human(display_long)|uniprotkb:RNF34(gene name)|psi-mi:RNF34(display_short)|uniprotkb:RING finger protein 34(gene name synonym)|uniprotkb:RING finger protein RIFF(gene name synonym)|uniprotkb:FYVE-RING finger protein Momo(gene name synonym)|uniprotkb:Human RING finger homologous to inhibitor of apoptosis protein(gene name synonym)|uniprotkb:Caspases-8 and -10-associated RING finger protein 1(gene name synonym)|uniprotkb:Caspase regulator CARP1(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RNF34(gene name synonym) psi-mi:anxa1_human(display_long)|uniprotkb:ANXA1(gene name)|psi-mi:ANXA1(display_short)|uniprotkb:ANX1(gene name synonym)|uniprotkb:LPC1(gene name synonym)|uniprotkb:Annexin-1(gene name synonym)|uniprotkb:Annexin I(gene name synonym)|uniprotkb:Lipocortin I(gene name synonym)|uniprotkb:Calpactin II(gene name synonym)|uniprotkb:Chromobindin-9(gene name synonym)|uniprotkb:p35(gene name synonym)|uniprotkb:Phospholipase A2 inhibitory protein(gene name synonym)|uniprotkb:Calpactin-2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483907|imex:IM-26985-431 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001243787.1|refseq:NP_079402.2|refseq:NP_919247.1|ensembl:ENSG00000170633(gene)|ensembl:ENST00000361234(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0012505"(endomembrane system)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035872"(nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|go:"GO:1901797"(negative regulation of signal transduction by p53 class mediator)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:2000374"(regulation of oxygen metabolic process)|go:"GO:2001271"(negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR036361|mint:Q969K3|reactome:R-HSA-6804757|reactome:R-HSA-983168 refseq:NP_000691.1|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030073"(insulin secretion)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030850"(prostate gland development)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0031313"(extrinsic component of endosome membrane)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0031514"(motile cilium)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032355"(response to estradiol)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0032652"(regulation of interleukin-1 production)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033031"(positive regulation of neutrophil apoptotic process)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036121"(double-stranded DNA helicase activity)|go:"GO:0042063"(gliogenesis)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042493"|go:"GO:0042629"(mast cell granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045087"(innate immune response)|go:"GO:0045627"(positive regulation of T-helper 1 cell differentiation)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0045920"(negative regulation of exocytosis)|go:"GO:0046632"(alpha-beta T cell differentiation)|ensembl:ENSG00000135046(gene)|ensembl:ENST00000257497(transcript)|ensembl:ENST00000376911(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0001780"(neutrophil homeostasis)|go:"GO:0001891"(phagocytic cup)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0002685"(regulation of leukocyte migration)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006909"(phagocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009986"(cell surface)|go:"GO:0010165"(response to X-ray)|go:"GO:0014839"(myoblast migration involved in skeletal muscle regeneration)|go:"GO:0016323"(basolateral plasma membrane)|refseq:XP_011516911.1|dip:DIP-32875N|go:"GO:0046883"(regulation of hormone secretion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0070459"(prolactin secretion)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071621"(granulocyte chemotaxis)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097350"(neutrophil clearance)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900138"(negative regulation of phospholipase A2 activity)|go:"GO:1990814"(DNA/DNA annealing activity)|interpro:IPR001464(Annexin)|interpro:IPR002388(Annexin, type I)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P04083|rcsb pdb:1AIN|rcsb pdb:1BO9|rcsb pdb:1QLS|rcsb pdb:5VFW|reactome:R-HSA-416476|reactome:R-HSA-418594|reactome:R-HSA-444473|reactome:R-HSA-445355|reactome:R-HSA-6785807|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050482"(arachidonic acid secretion)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0050727"(regulation of inflammatory response) - - comment:"author score: 50" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pvINlXbJ9UfZbyW4YqRO+HQsCnw9606 rogid:QKmqz+UsAof35B/so2qKLQjn2v09606 rigid:VMIlUbljvn92BC6tgZjW0HYzqRw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27694 uniprotkb:P15927 intact:EBI-621389|ensembl:ENSP00000254719|uniprotkb:Q59ES9|uniprotkb:A8K0Y9 intact:EBI-621404|ensembl:ENSP00000363021|uniprotkb:Q52II0|uniprotkb:Q5TEI9|uniprotkb:Q5TEJ5 psi-mi:rfa1_human(display_long)|uniprotkb:Replication factor A protein 1(gene name synonym)|uniprotkb:Single-stranded DNA-binding protein(gene name synonym)|uniprotkb:RPA1(gene name)|psi-mi:RPA1(display_short)|uniprotkb:REPA1(gene name synonym)|uniprotkb:RPA70(gene name synonym) psi-mi:rfa2_human(display_long)|uniprotkb:RPA34(gene name synonym)|uniprotkb:Replication protein A 34 kDa subunit(gene name synonym)|uniprotkb:Replication factor A protein 2(gene name synonym)|uniprotkb:RPA2(gene name)|psi-mi:RPA2(display_short)|uniprotkb:REPA2(gene name synonym)|uniprotkb:RPA32(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483931|imex:IM-26985-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132383(gene)|ensembl:ENST00000254719(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0016605"(PML body)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0090734"(site of DNA damage)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004591(Replication factor-a protein 1 Rpa1)|interpro:IPR007199(Replication factor-A protein 1, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013955(Replication factor-A, C-terminal)|interpro:IPR031657|go:"GO:0006268"(DNA unwinding involved in DNA replication)|mint:P27694|rcsb pdb:1EWI|rcsb pdb:1FGU|rcsb pdb:1JMC|rcsb pdb:1L1O|rcsb pdb:2B29|rcsb pdb:2B3G|rcsb pdb:4IJH|rcsb pdb:4IJL|rcsb pdb:4IPC|rcsb pdb:4IPD|rcsb pdb:4IPG|rcsb pdb:4IPH|rcsb pdb:4LUO|rcsb pdb:4LUV|rcsb pdb:4LUZ|rcsb pdb:4LW1|rcsb pdb:4LWC|rcsb pdb:4NB3|rcsb pdb:4O0A|rcsb pdb:4R4C|rcsb pdb:4R4I|rcsb pdb:4R4O|rcsb pdb:4R4Q|rcsb pdb:4R4T|rcsb pdb:5E7N|rcsb pdb:5EAY|rcsb pdb:5N85|rcsb pdb:5N8A|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|reactome:R-HSA-3108214|refseq:NP_002936.1|dip:DIP-24189N rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:1Z1D|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|rcsb pdb:4MQV|rcsb pdb:4OU0|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|rcsb pdb:1DPU|ensembl:ENSG00000117748(gene)|ensembl:ENST00000373912(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014646(Replication protein A, subunit RPA32)|interpro:IPR014892(Replication protein A C terminal)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040260|mint:P15927|refseq:NP_001273005.1|refseq:NP_002937.1|refseq:NP_001284487.1|dip:DIP-24187N - - comment:"author score: 280" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:DRZpMUlGyS0Qa5XFEtx71k0iPig9606 rogid:+Ute8Lq5hnN0sLAQNWZb0cAbcTI9606 rigid:AYgkuF3hoG1X1oDSAdCBMi2v/G4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27694 uniprotkb:P35244 intact:EBI-621389|ensembl:ENSP00000254719|uniprotkb:Q59ES9|uniprotkb:A8K0Y9 intact:EBI-621428|ensembl:ENSP00000223129|ensembl:ENSP00000379914|uniprotkb:Q549U6|intact:EBI-1058317 psi-mi:rfa1_human(display_long)|uniprotkb:Replication factor A protein 1(gene name synonym)|uniprotkb:Single-stranded DNA-binding protein(gene name synonym)|uniprotkb:RPA1(gene name)|psi-mi:RPA1(display_short)|uniprotkb:REPA1(gene name synonym)|uniprotkb:RPA70(gene name synonym) psi-mi:rfa3_human(display_long)|uniprotkb:Replication factor A protein 3(gene name synonym)|uniprotkb:RPA3(gene name)|psi-mi:RPA3(display_short)|uniprotkb:REPA3(gene name synonym)|uniprotkb:RPA14(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483931|imex:IM-26985-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132383(gene)|ensembl:ENST00000254719(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0016605"(PML body)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0090734"(site of DNA damage)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004591(Replication factor-a protein 1 Rpa1)|interpro:IPR007199(Replication factor-A protein 1, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013955(Replication factor-A, C-terminal)|interpro:IPR031657|go:"GO:0006268"(DNA unwinding involved in DNA replication)|mint:P27694|rcsb pdb:1EWI|rcsb pdb:1FGU|rcsb pdb:1JMC|rcsb pdb:1L1O|rcsb pdb:2B29|rcsb pdb:2B3G|rcsb pdb:4IJH|rcsb pdb:4IJL|rcsb pdb:4IPC|rcsb pdb:4IPD|rcsb pdb:4IPG|rcsb pdb:4IPH|rcsb pdb:4LUO|rcsb pdb:4LUV|rcsb pdb:4LUZ|rcsb pdb:4LW1|rcsb pdb:4LWC|rcsb pdb:4NB3|rcsb pdb:4O0A|rcsb pdb:4R4C|rcsb pdb:4R4I|rcsb pdb:4R4O|rcsb pdb:4R4Q|rcsb pdb:4R4T|rcsb pdb:5E7N|rcsb pdb:5EAY|rcsb pdb:5N85|rcsb pdb:5N8A|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|reactome:R-HSA-3108214|refseq:NP_002936.1|dip:DIP-24189N go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0035861"(site of double-strand break)|ensembl:ENSG00000106399(gene)|go:"GO:0042127"(regulation of cell population proliferation)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013970(Replication factor A protein 3)|mint:P35244|rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|ensembl:ENST00000223129(transcript)|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|ensembl:ENST00000396682(transcript)|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|refseq:NP_002938.1|dip:DIP-24190N - - comment:"author score: 415" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:DRZpMUlGyS0Qa5XFEtx71k0iPig9606 rogid:hHO7MxGGHUjz30HXSBZd9cXOq6I9606 rigid:AYgkuF3hoG1X1oDSAdCBMi2v/G4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27694 uniprotkb:P12956 intact:EBI-621389|ensembl:ENSP00000254719|uniprotkb:Q59ES9|uniprotkb:A8K0Y9 intact:EBI-353208|ensembl:ENSP00000352257|ensembl:ENSP00000353192|ensembl:ENSP00000384257|intact:EBI-2843064|uniprotkb:Q6FG89|uniprotkb:Q9UCQ2|uniprotkb:Q9UCQ3|intact:EBI-8456785|intact:MINT-8429298|uniprotkb:B1AHC8 psi-mi:rfa1_human(display_long)|uniprotkb:Replication factor A protein 1(gene name synonym)|uniprotkb:Single-stranded DNA-binding protein(gene name synonym)|uniprotkb:RPA1(gene name)|psi-mi:RPA1(display_short)|uniprotkb:REPA1(gene name synonym)|uniprotkb:RPA70(gene name synonym) psi-mi:xrcc6_human(display_long)|uniprotkb:XRCC6(gene name)|psi-mi:XRCC6(display_short)|uniprotkb:G22P1(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 70 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p70(gene name synonym)|uniprotkb:70 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 75 kDa subunit(gene name synonym)|uniprotkb:DNA repair protein XRCC6(gene name synonym)|uniprotkb:X-ray repair complementing defective repair in Chinese hamster cells 6(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 1(gene name synonym)|uniprotkb:5'-deoxyribose-5-phosphate lyase Ku70(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483931|imex:IM-26985-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132383(gene)|ensembl:ENST00000254719(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0016605"(PML body)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0090734"(site of DNA damage)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004591(Replication factor-a protein 1 Rpa1)|interpro:IPR007199(Replication factor-A protein 1, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013955(Replication factor-A, C-terminal)|interpro:IPR031657|go:"GO:0006268"(DNA unwinding involved in DNA replication)|mint:P27694|rcsb pdb:1EWI|rcsb pdb:1FGU|rcsb pdb:1JMC|rcsb pdb:1L1O|rcsb pdb:2B29|rcsb pdb:2B3G|rcsb pdb:4IJH|rcsb pdb:4IJL|rcsb pdb:4IPC|rcsb pdb:4IPD|rcsb pdb:4IPG|rcsb pdb:4IPH|rcsb pdb:4LUO|rcsb pdb:4LUV|rcsb pdb:4LUZ|rcsb pdb:4LW1|rcsb pdb:4LWC|rcsb pdb:4NB3|rcsb pdb:4O0A|rcsb pdb:4R4C|rcsb pdb:4R4I|rcsb pdb:4R4O|rcsb pdb:4R4Q|rcsb pdb:4R4T|rcsb pdb:5E7N|rcsb pdb:5EAY|rcsb pdb:5N85|rcsb pdb:5N8A|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|reactome:R-HSA-3108214|refseq:NP_002936.1|dip:DIP-24189N go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR006165(DNA helicase, ATP-dependent, Ku70 subunit)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR027388|interpro:IPR036361|interpro:IPR036465|mint:P12956|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1JJR|rcsb pdb:3RZX|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZHA|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|rcsb pdb:6ZHE|rcsb pdb:7AXZ|interpro:IPR003034(DNA-binding SAP)|rcsb pdb:7K0Y|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000196419(gene)|go:"GO:0005829"(cytosol)|go:"GO:0006266"(DNA ligation)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|ensembl:ENST00000359308(transcript)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|ensembl:ENST00000360079(transcript)|ensembl:ENST00000405878(transcript)|go:"GO:0016020"(membrane)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|refseq:NP_001460.1|refseq:NP_001275906.1|refseq:NP_001275905.1|dip:DIP-24188N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:DRZpMUlGyS0Qa5XFEtx71k0iPig9606 rogid:45wj3HmNJ4dfVgw0zc2r3AUZ0Dw9606 rigid:AYgkuF3hoG1X1oDSAdCBMi2v/G4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27694 uniprotkb:Q04837 intact:EBI-621389|ensembl:ENSP00000254719|uniprotkb:Q59ES9|uniprotkb:A8K0Y9 intact:EBI-353460|ensembl:ENSP00000265304|ensembl:ENSP00000419388|ensembl:ENSP00000419541|ensembl:ENSP00000419665|ensembl:ENSP00000420485|ensembl:ENSP00000458815|ensembl:ENSP00000459208|ensembl:ENSP00000459367|ensembl:ENSP00000460028|ensembl:ENSP00000461884|ensembl:ENSP00000480488 psi-mi:rfa1_human(display_long)|uniprotkb:Replication factor A protein 1(gene name synonym)|uniprotkb:Single-stranded DNA-binding protein(gene name synonym)|uniprotkb:RPA1(gene name)|psi-mi:RPA1(display_short)|uniprotkb:REPA1(gene name synonym)|uniprotkb:RPA70(gene name synonym) psi-mi:ssbp_human(display_long)|uniprotkb:SSBP1(gene name)|psi-mi:SSBP1(display_short)|uniprotkb:SSBP(gene name synonym)|uniprotkb:PWP1-interacting protein 17(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483931|imex:IM-26985-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132383(gene)|ensembl:ENST00000254719(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0016605"(PML body)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0090734"(site of DNA damage)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004591(Replication factor-a protein 1 Rpa1)|interpro:IPR007199(Replication factor-A protein 1, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013955(Replication factor-A, C-terminal)|interpro:IPR031657|go:"GO:0006268"(DNA unwinding involved in DNA replication)|mint:P27694|rcsb pdb:1EWI|rcsb pdb:1FGU|rcsb pdb:1JMC|rcsb pdb:1L1O|rcsb pdb:2B29|rcsb pdb:2B3G|rcsb pdb:4IJH|rcsb pdb:4IJL|rcsb pdb:4IPC|rcsb pdb:4IPD|rcsb pdb:4IPG|rcsb pdb:4IPH|rcsb pdb:4LUO|rcsb pdb:4LUV|rcsb pdb:4LUZ|rcsb pdb:4LW1|rcsb pdb:4LWC|rcsb pdb:4NB3|rcsb pdb:4O0A|rcsb pdb:4R4C|rcsb pdb:4R4I|rcsb pdb:4R4O|rcsb pdb:4R4Q|rcsb pdb:4R4T|rcsb pdb:5E7N|rcsb pdb:5EAY|rcsb pdb:5N85|rcsb pdb:5N8A|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|reactome:R-HSA-3108214|refseq:NP_002936.1|dip:DIP-24189N refseq:NP_003134.1|refseq:NP_001243439.1|refseq:NP_001243440.1|refseq:NP_001243441.1|refseq:NP_001243442.1|ensembl:ENSG00000106028(gene)|ensembl:ENSG00000262771(gene)|ensembl:ENST00000265304(transcript)|ensembl:ENST00000465582(transcript)|ensembl:ENST00000481508(transcript)|ensembl:ENST00000484178(transcript)|ensembl:ENST00000498107(transcript)|ensembl:ENST00000570667(transcript)|ensembl:ENST00000571430(transcript)|ensembl:ENST00000574199(transcript)|ensembl:ENST00000575059(transcript)|ensembl:ENST00000576834(transcript)|ensembl:ENST00000612337(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|go:"GO:1905776"(positive regulation of DNA helicase activity)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:Q04837|rcsb pdb:1S3O|rcsb pdb:2DUD|rcsb pdb:3ULL|rcsb pdb:6RUP|reactome:R-HSA-2151201 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:DRZpMUlGyS0Qa5XFEtx71k0iPig9606 rogid:W/7kbgBRtYcjJfr2XbA1OK9BOS49606 rigid:AYgkuF3hoG1X1oDSAdCBMi2v/G4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P27694 uniprotkb:P40937 intact:EBI-621389|ensembl:ENSP00000254719|uniprotkb:Q59ES9|uniprotkb:A8K0Y9 intact:EBI-712376|ensembl:ENSP00000408295|uniprotkb:A8MZ62|uniprotkb:B3KSX8 psi-mi:rfa1_human(display_long)|uniprotkb:Replication factor A protein 1(gene name synonym)|uniprotkb:Single-stranded DNA-binding protein(gene name synonym)|uniprotkb:RPA1(gene name)|psi-mi:RPA1(display_short)|uniprotkb:REPA1(gene name synonym)|uniprotkb:RPA70(gene name synonym) psi-mi:rfc5_human(display_long)|uniprotkb:Activator 1 subunit 5(gene name synonym)|uniprotkb:Replication factor C 36 kDa subunit(gene name synonym)|uniprotkb:Activator 1 36 kDa subunit(gene name synonym)|uniprotkb:RFC5(gene name)|psi-mi:RFC5(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483931|imex:IM-26985-51 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000132383(gene)|ensembl:ENST00000254719(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0016605"(PML body)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0090734"(site of DNA damage)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004591(Replication factor-a protein 1 Rpa1)|interpro:IPR007199(Replication factor-A protein 1, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013955(Replication factor-A, C-terminal)|interpro:IPR031657|go:"GO:0006268"(DNA unwinding involved in DNA replication)|mint:P27694|rcsb pdb:1EWI|rcsb pdb:1FGU|rcsb pdb:1JMC|rcsb pdb:1L1O|rcsb pdb:2B29|rcsb pdb:2B3G|rcsb pdb:4IJH|rcsb pdb:4IJL|rcsb pdb:4IPC|rcsb pdb:4IPD|rcsb pdb:4IPG|rcsb pdb:4IPH|rcsb pdb:4LUO|rcsb pdb:4LUV|rcsb pdb:4LUZ|rcsb pdb:4LW1|rcsb pdb:4LWC|rcsb pdb:4NB3|rcsb pdb:4O0A|rcsb pdb:4R4C|rcsb pdb:4R4I|rcsb pdb:4R4O|rcsb pdb:4R4Q|rcsb pdb:4R4T|rcsb pdb:5E7N|rcsb pdb:5EAY|rcsb pdb:5N85|rcsb pdb:5N8A|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|reactome:R-HSA-3108214|refseq:NP_002936.1|dip:DIP-24189N refseq:NP_031396.1|refseq:NP_853556.2|ensembl:ENSG00000111445(gene)|ensembl:ENST00000454402(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0019899"(enzyme binding)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|mint:P40937|rcsb pdb:1LFS|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-176187|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804756|reactome:R-HSA-69091|reactome:R-HSA-69473|refseq:XP_011536945.1|refseq:XP_011536947.1|refseq:NP_001123584.1|refseq:NP_001123585.1|dip:DIP-36433N - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:DRZpMUlGyS0Qa5XFEtx71k0iPig9606 rogid:F7oadHDk6fkhHn+3rDF9K2JHSl49606 rigid:AYgkuF3hoG1X1oDSAdCBMi2v/G4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35244 uniprotkb:P15927 intact:EBI-621428|ensembl:ENSP00000223129|ensembl:ENSP00000379914|uniprotkb:Q549U6|intact:EBI-1058317 intact:EBI-621404|ensembl:ENSP00000363021|uniprotkb:Q52II0|uniprotkb:Q5TEI9|uniprotkb:Q5TEJ5 psi-mi:rfa3_human(display_long)|uniprotkb:Replication factor A protein 3(gene name synonym)|uniprotkb:RPA3(gene name)|psi-mi:RPA3(display_short)|uniprotkb:REPA3(gene name synonym)|uniprotkb:RPA14(gene name synonym) psi-mi:rfa2_human(display_long)|uniprotkb:RPA34(gene name synonym)|uniprotkb:Replication protein A 34 kDa subunit(gene name synonym)|uniprotkb:Replication factor A protein 2(gene name synonym)|uniprotkb:RPA2(gene name)|psi-mi:RPA2(display_short)|uniprotkb:REPA2(gene name synonym)|uniprotkb:RPA32(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25483952|imex:IM-26985-271 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0035861"(site of double-strand break)|ensembl:ENSG00000106399(gene)|go:"GO:0042127"(regulation of cell population proliferation)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013970(Replication factor A protein 3)|mint:P35244|rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|ensembl:ENST00000223129(transcript)|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|ensembl:ENST00000396682(transcript)|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|refseq:NP_002938.1|dip:DIP-24190N rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:1Z1D|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|rcsb pdb:4MQV|rcsb pdb:4OU0|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|rcsb pdb:1DPU|ensembl:ENSG00000117748(gene)|ensembl:ENST00000373912(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014646(Replication protein A, subunit RPA32)|interpro:IPR014892(Replication protein A C terminal)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040260|mint:P15927|refseq:NP_001273005.1|refseq:NP_002937.1|refseq:NP_001284487.1|dip:DIP-24187N - comment:"author score: 494" - figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:hHO7MxGGHUjz30HXSBZd9cXOq6I9606 rogid:+Ute8Lq5hnN0sLAQNWZb0cAbcTI9606 rigid:+F08a1buBq1wsTk9M+okNAwGtIg false - tandem tag:n-n - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95072 uniprotkb:Q9UNE7 intact:EBI-9361206|uniprotkb:Q658V5|uniprotkb:Q6IA92|uniprotkb:D3DS62|uniprotkb:Q8WUV8|uniprotkb:A8K576|uniprotkb:Q9NVQ9|uniprotkb:Q9BTF2|ensembl:ENSP00000482439|ensembl:ENSP00000482546|ensembl:ENSP00000493523|ensembl:ENSP00000495458 intact:EBI-357085|uniprotkb:O60526|uniprotkb:Q969U2|uniprotkb:Q9HBT1|uniprotkb:A2IDB9|ensembl:ENSP00000219548 psi-mi:rec8_human(display_long)|uniprotkb:REC8(gene name)|psi-mi:REC8(display_short)|uniprotkb:Cohesin Rec8p(gene name synonym)|uniprotkb:REC8L1(gene name synonym) psi-mi:chip_human(display_long)|uniprotkb:CHIP(gene name synonym)|uniprotkb:STUB1(gene name)|psi-mi:STUB1(display_short)|uniprotkb:PP1131(orf name)|uniprotkb:Carboxy terminus of Hsp70-interacting protein(gene name synonym)|uniprotkb:STIP1 homology and U box-containing protein 1(gene name synonym)|uniprotkb:CLL-associated antigen KW-8(gene name synonym)|uniprotkb:Antigen NY-CO-7(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CHIP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483697|imex:IM-26985-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041670.1|refseq:NP_005123.2|ensembl:ENSG00000100918(gene)|ensembl:ENSG00000285007(gene)|ensembl:ENST00000611366(transcript)|ensembl:ENST00000620473(transcript)|ensembl:ENST00000642486(transcript)|ensembl:ENST00000646765(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0009566"(fertilization)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|mint:O95072|reactome:R-HSA-1221632 dip:DIP-29752N|refseq:NP_005852.2|refseq:NP_001280126.1|ensembl:ENSG00000103266(gene)|ensembl:ENST00000219548(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031943"(regulation of glucocorticoid metabolic process)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046332"(SMAD binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0030579"(ubiquitin-dependent SMAD protein catabolic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090035"(positive regulation of chaperone-mediated protein complex assembly)|go:"GO:0101031"(chaperone complex)|interpro:IPR003613(U box)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019734|interpro:IPR041312|mint:Q9UNE7|rcsb pdb:4KBQ|rcsb pdb:6EFK|rcsb pdb:6NSV|reactome:R-HSA-2173788|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-8863795|reactome:R-HSA-8939902|reactome:R-HSA-8948751|reactome:R-HSA-983168 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:DQKOCe+CcQ6mDGL+8bpeW0PGbe49606 rogid:h4QyIM0TptgkQppPUgiKn68XjP49606 rigid:FymqM4gX+wzaAQJ9KmmmeMhJTCE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95072 uniprotkb:P34931 intact:EBI-9361206|uniprotkb:Q658V5|uniprotkb:Q6IA92|uniprotkb:D3DS62|uniprotkb:Q8WUV8|uniprotkb:A8K576|uniprotkb:Q9NVQ9|uniprotkb:Q9BTF2|ensembl:ENSP00000482439|ensembl:ENSP00000482546|ensembl:ENSP00000493523|ensembl:ENSP00000495458 intact:EBI-354912|uniprotkb:O75634|uniprotkb:Q2HXR3|uniprotkb:Q8NE72|uniprotkb:A6NNB0|uniprotkb:Q96QC9|uniprotkb:Q9UQM1|uniprotkb:B0UXW8|ensembl:ENSP00000364805|ensembl:ENSP00000372881|ensembl:ENSP00000396486|ensembl:ENSP00000408347 psi-mi:rec8_human(display_long)|uniprotkb:REC8(gene name)|psi-mi:REC8(display_short)|uniprotkb:Cohesin Rec8p(gene name synonym)|uniprotkb:REC8L1(gene name synonym) psi-mi:hs71l_human(display_long)|uniprotkb:HSPA1L(gene name)|psi-mi:HSPA1L(display_short)|uniprotkb:Heat shock 70 kDa protein 1-Hom(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483697|imex:IM-26985-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041670.1|refseq:NP_005123.2|ensembl:ENSG00000100918(gene)|ensembl:ENSG00000285007(gene)|ensembl:ENST00000611366(transcript)|ensembl:ENST00000620473(transcript)|ensembl:ENST00000642486(transcript)|ensembl:ENST00000646765(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0009566"(fertilization)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|mint:O95072|reactome:R-HSA-1221632 refseq:NP_005518.3|ensembl:ENSG00000204390(gene)|ensembl:ENSG00000206383(gene)|ensembl:ENSG00000234258(gene)|ensembl:ENSG00000236251(gene)|ensembl:ENST00000375654(transcript)|ensembl:ENST00000383390(transcript)|ensembl:ENST00000417601(transcript)|ensembl:ENST00000456772(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0072562"(blood microparticle)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P34931|rcsb pdb:3GDQ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:DQKOCe+CcQ6mDGL+8bpeW0PGbe49606 rogid:KS02DcMpD2sxSF36hUjKiSdYi4c9606 rigid:FymqM4gX+wzaAQJ9KmmmeMhJTCE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95072 uniprotkb:Q9HCS7 intact:EBI-9361206|uniprotkb:Q658V5|uniprotkb:Q6IA92|uniprotkb:D3DS62|uniprotkb:Q8WUV8|uniprotkb:A8K576|uniprotkb:Q9NVQ9|uniprotkb:Q9BTF2|ensembl:ENSP00000482439|ensembl:ENSP00000482546|ensembl:ENSP00000493523|ensembl:ENSP00000495458 intact:EBI-295232|uniprotkb:Q8TET6|uniprotkb:Q96HB0|uniprotkb:Q96IW0|uniprotkb:Q9NRG6|uniprotkb:Q9ULP3|ensembl:ENSP00000351137 psi-mi:rec8_human(display_long)|uniprotkb:REC8(gene name)|psi-mi:REC8(display_short)|uniprotkb:Cohesin Rec8p(gene name synonym)|uniprotkb:REC8L1(gene name synonym) psi-mi:syf1_human(display_long)|uniprotkb:XAB2(gene name)|psi-mi:XAB2(display_short)|uniprotkb:HCNP(gene name synonym)|uniprotkb:KIAA1177(gene name synonym)|uniprotkb:PP3898(orf name)|uniprotkb:SYF1(gene name synonym)|uniprotkb:XPA-binding protein 2(gene name synonym)|uniprotkb:Protein HCNP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483697|imex:IM-26985-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041670.1|refseq:NP_005123.2|ensembl:ENSG00000100918(gene)|ensembl:ENSG00000285007(gene)|ensembl:ENST00000611366(transcript)|ensembl:ENST00000620473(transcript)|ensembl:ENST00000642486(transcript)|ensembl:ENST00000646765(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0009566"(fertilization)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|mint:O95072|reactome:R-HSA-1221632 refseq:NP_064581.2|dip:DIP-31646N|ensembl:ENSG00000076924(gene)|ensembl:ENST00000358368(transcript)|go:"GO:0000349"(generation of catalytic spliceosome for first transesterification step)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001824"(blastocyst development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0016020"(membrane)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|interpro:IPR003107(RNA-processing protein, HAT helix)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q9HCS7|rcsb pdb:5MQF|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:DQKOCe+CcQ6mDGL+8bpeW0PGbe49606 rogid:6+Vu8QmYaVK/kd5ADY6uaUY35SQ9606 rigid:FymqM4gX+wzaAQJ9KmmmeMhJTCE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95072 uniprotkb:O00165 intact:EBI-9361206|uniprotkb:Q658V5|uniprotkb:Q6IA92|uniprotkb:D3DS62|uniprotkb:Q8WUV8|uniprotkb:A8K576|uniprotkb:Q9NVQ9|uniprotkb:Q9BTF2|ensembl:ENSP00000482439|ensembl:ENSP00000482546|ensembl:ENSP00000493523|ensembl:ENSP00000495458 intact:EBI-357001|uniprotkb:A8W4W9|uniprotkb:A8W4X0|uniprotkb:B4DUJ7|uniprotkb:Q5VYD7|uniprotkb:Q5VYD5|uniprotkb:Q96AU4|uniprotkb:Q9BS80|ensembl:ENSP00000329002 psi-mi:rec8_human(display_long)|uniprotkb:REC8(gene name)|psi-mi:REC8(display_short)|uniprotkb:Cohesin Rec8p(gene name synonym)|uniprotkb:REC8L1(gene name synonym) psi-mi:hax1_human(display_long)|uniprotkb:HAX1(gene name)|psi-mi:HAX1(display_short)|uniprotkb:HS1BP1(gene name synonym)|uniprotkb:HS1-associating protein X-1(gene name synonym)|uniprotkb:HS1-binding protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483697|imex:IM-26985-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041670.1|refseq:NP_005123.2|ensembl:ENSG00000100918(gene)|ensembl:ENSG00000285007(gene)|ensembl:ENST00000611366(transcript)|ensembl:ENST00000620473(transcript)|ensembl:ENST00000642486(transcript)|ensembl:ENST00000646765(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0009566"(fertilization)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|mint:O95072|reactome:R-HSA-1221632 refseq:NP_001018238.1|refseq:NP_006109.2|dip:DIP-36771N|ensembl:ENSG00000143575(gene)|ensembl:ENST00000328703(transcript)|go:"GO:0000932"(P-body)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005938"(cell cortex)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019966"(interleukin-1 binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030854"(positive regulation of granulocyte differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071345"(cellular response to cytokine stimulus)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903214"(regulation of protein targeting to mitochondrion)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR017248(HS1-associating, X-1)|mint:O00165 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:DQKOCe+CcQ6mDGL+8bpeW0PGbe49606 rogid:XRyEPYge2cQFiWdmOaiNIAxd1yQ9606 rigid:FymqM4gX+wzaAQJ9KmmmeMhJTCE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95072 uniprotkb:P35998 intact:EBI-9361206|uniprotkb:Q658V5|uniprotkb:Q6IA92|uniprotkb:D3DS62|uniprotkb:Q8WUV8|uniprotkb:A8K576|uniprotkb:Q9NVQ9|uniprotkb:Q9BTF2|ensembl:ENSP00000482439|ensembl:ENSP00000482546|ensembl:ENSP00000493523|ensembl:ENSP00000495458 intact:EBI-359710|uniprotkb:B7Z5E2|uniprotkb:A4D0Q1|uniprotkb:Q3LIA5|uniprotkb:Q9UDI3|ensembl:ENSP00000292644|ensembl:ENSP00000391211|ensembl:ENSP00000502939|ensembl:ENSP00000503179|ensembl:ENSP00000504608 psi-mi:rec8_human(display_long)|uniprotkb:REC8(gene name)|psi-mi:REC8(display_short)|uniprotkb:Cohesin Rec8p(gene name synonym)|uniprotkb:REC8L1(gene name synonym) psi-mi:prs7_human(display_long)|uniprotkb:PSMC2(gene name)|psi-mi:PSMC2(display_short)|uniprotkb:MSS1(gene name synonym)|uniprotkb:Proteasome 26S subunit ATPase 2(gene name synonym)|uniprotkb:Protein MSS1(gene name synonym)|uniprotkb:26S proteasome AAA-ATPase subunit RPT1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483697|imex:IM-26985-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041670.1|refseq:NP_005123.2|ensembl:ENSG00000100918(gene)|ensembl:ENSG00000285007(gene)|ensembl:ENST00000611366(transcript)|ensembl:ENST00000620473(transcript)|ensembl:ENST00000642486(transcript)|ensembl:ENST00000646765(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0009566"(fertilization)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|mint:O95072|reactome:R-HSA-1221632 refseq:NP_001191382.1|refseq:NP_002794.1|interpro:IPR005937(26S proteasome subunit P45)|interpro:IPR027417|interpro:IPR035245|interpro:IPR041569|mint:P35998|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|interpro:IPR003960(AAA ATPase, conserved site)|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHJ|rcsb pdb:5VHM|rcsb pdb:5VHN|rcsb pdb:5VHO|rcsb pdb:5VHP|ensembl:ENSG00000161057(gene)|ensembl:ENST00000292644(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|ensembl:ENST00000435765(transcript)|ensembl:ENST00000678493(transcript)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0016020"(membrane)|ensembl:ENST00000679205(transcript)|ensembl:ENST00000679341(transcript)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0036402"(proteasome-activating activity)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0000502"(proteasome complex)|go:"GO:0000932"(P-body)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0043197"(dendritic spine)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|rcsb pdb:5VHR|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|rcsb pdb:5VHQ|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-6798695|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5610780|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|dip:DIP-27554N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:DQKOCe+CcQ6mDGL+8bpeW0PGbe49606 rogid:ahQfjPKywP5DWNq3FB5XCjuqkJ09606 rigid:FymqM4gX+wzaAQJ9KmmmeMhJTCE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95072 uniprotkb:Q9Y5V3 intact:EBI-9361206|uniprotkb:Q658V5|uniprotkb:Q6IA92|uniprotkb:D3DS62|uniprotkb:Q8WUV8|uniprotkb:A8K576|uniprotkb:Q9NVQ9|uniprotkb:Q9BTF2|ensembl:ENSP00000482439|ensembl:ENSP00000482546|ensembl:ENSP00000493523|ensembl:ENSP00000495458 intact:EBI-716006|uniprotkb:Q5VSH6|uniprotkb:Q8IZ84|uniprotkb:Q8WY92|uniprotkb:Q9H352|uniprotkb:Q9HBT4|uniprotkb:Q9UF36|ensembl:ENSP00000325333|ensembl:ENSP00000364874|ensembl:ENSP00000364927 psi-mi:rec8_human(display_long)|uniprotkb:REC8(gene name)|psi-mi:REC8(display_short)|uniprotkb:Cohesin Rec8p(gene name synonym)|uniprotkb:REC8L1(gene name synonym) psi-mi:magd1_human(display_long)|uniprotkb:MAGE-D1 antigen(gene name synonym)|uniprotkb:Neurotrophin receptor-interacting MAGE homolog(gene name synonym)|uniprotkb:MAGE tumor antigen CCF(gene name synonym)|uniprotkb:MAGED1(gene name)|psi-mi:MAGED1(display_short)|uniprotkb:NRAGE(gene name synonym)|uniprotkb:PRO2292(orf name)|uniprotkb:PP2250(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483697|imex:IM-26985-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041670.1|refseq:NP_005123.2|ensembl:ENSG00000100918(gene)|ensembl:ENSG00000285007(gene)|ensembl:ENST00000611366(transcript)|ensembl:ENST00000620473(transcript)|ensembl:ENST00000642486(transcript)|ensembl:ENST00000646765(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0009566"(fertilization)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|mint:O95072|reactome:R-HSA-1221632 refseq:NP_001005332.1|refseq:NP_001005333.1|refseq:NP_008917.3|ensembl:ENSP00000325333|ensembl:ENST00000375695|ensembl:ENSP00000364847|ensembl:ENSP00000364874|ensembl:ENSP00000364927|refseq:XP_011529137.1|refseq:XP_016885467.1|refseq:XP_016885468.1|refseq:XP_016885469.1|ensembl:ENSG00000179222(gene)|ensembl:ENST00000326587(transcript)|ensembl:ENST00000375722(transcript)|ensembl:ENST00000375772(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0090190"(positive regulation of branching involved in ureteric bud morphogenesis)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR002190(MAGE protein)|interpro:IPR030083|interpro:IPR037445|interpro:IPR041898|interpro:IPR041899|mint:Q9Y5V3|reactome:R-HSA-193648|reactome:R-HSA-418889 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:DQKOCe+CcQ6mDGL+8bpeW0PGbe49606 rogid:UTg0r4zGMXfTZqBN4SFmgu6IukI9606 rigid:FymqM4gX+wzaAQJ9KmmmeMhJTCE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95072 uniprotkb:Q9H078 intact:EBI-9361206|uniprotkb:Q658V5|uniprotkb:Q6IA92|uniprotkb:D3DS62|uniprotkb:Q8WUV8|uniprotkb:A8K576|uniprotkb:Q9NVQ9|uniprotkb:Q9BTF2|ensembl:ENSP00000482439|ensembl:ENSP00000482546|ensembl:ENSP00000493523|ensembl:ENSP00000495458 intact:EBI-2107221|uniprotkb:Q8ND11|uniprotkb:Q9H8Y0|uniprotkb:B4DXW4|uniprotkb:B4DXJ7|uniprotkb:B4DXP7|uniprotkb:E7EWN6|uniprotkb:F8W7P6|ensembl:ENSP00000294053 psi-mi:rec8_human(display_long)|uniprotkb:REC8(gene name)|psi-mi:REC8(display_short)|uniprotkb:Cohesin Rec8p(gene name synonym)|uniprotkb:REC8L1(gene name synonym) psi-mi:clpb_human(display_long)|uniprotkb:CLPB(gene name)|psi-mi:CLPB(display_short)|uniprotkb:HSP78(gene name synonym)|uniprotkb:SKD3(gene name synonym)|uniprotkb:Suppressor of potassium transport defect 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483697|imex:IM-26985-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041670.1|refseq:NP_005123.2|ensembl:ENSG00000100918(gene)|ensembl:ENSG00000285007(gene)|ensembl:ENST00000611366(transcript)|ensembl:ENST00000620473(transcript)|ensembl:ENST00000642486(transcript)|ensembl:ENST00000646765(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0009566"(fertilization)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|mint:O95072|reactome:R-HSA-1221632 refseq:NP_110440.1|refseq:NP_001245321.1|refseq:NP_001245322.1|refseq:NP_001245323.1|ensembl:ENSG00000162129(gene)|ensembl:ENST00000294053(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0034605"(cellular response to heat)|go:"GO:0039529"(RIG-I signaling pathway)|go:"GO:0140374"(antiviral innate immune response)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001270(Chaperonin clpA/B)|interpro:IPR002110(Ankyrin)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR019489|interpro:IPR020683|interpro:IPR027417|interpro:IPR036770|mint:Q9H078 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:DQKOCe+CcQ6mDGL+8bpeW0PGbe49606 rogid:QqIOYOITwDC+c8kKtMGBHa/0Tjk9606 rigid:FymqM4gX+wzaAQJ9KmmmeMhJTCE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95072 uniprotkb:Q9ULR0 intact:EBI-9361206|uniprotkb:Q658V5|uniprotkb:Q6IA92|uniprotkb:D3DS62|uniprotkb:Q8WUV8|uniprotkb:A8K576|uniprotkb:Q9NVQ9|uniprotkb:Q9BTF2|ensembl:ENSP00000482439|ensembl:ENSP00000482546|ensembl:ENSP00000493523|ensembl:ENSP00000495458 intact:EBI-2557660|uniprotkb:Q9BT05|uniprotkb:Q96IL2|ensembl:ENSP00000376973 psi-mi:rec8_human(display_long)|uniprotkb:REC8(gene name)|psi-mi:REC8(display_short)|uniprotkb:Cohesin Rec8p(gene name synonym)|uniprotkb:REC8L1(gene name synonym) psi-mi:isy1_human(display_long)|uniprotkb:ISY1(gene name)|psi-mi:ISY1(display_short)|uniprotkb:KIAA1160(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483697|imex:IM-26985-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041670.1|refseq:NP_005123.2|ensembl:ENSG00000100918(gene)|ensembl:ENSG00000285007(gene)|ensembl:ENST00000611366(transcript)|ensembl:ENST00000620473(transcript)|ensembl:ENST00000642486(transcript)|ensembl:ENST00000646765(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0009566"(fertilization)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|mint:O95072|reactome:R-HSA-1221632 refseq:NP_001186398.1|refseq:NP_001191819.1|refseq:NP_065752.1|dip:DIP-56636N|ensembl:ENSG00000240682(gene)|ensembl:ENST00000393295(transcript)|go:"GO:0000350"(generation of catalytic spliceosome for second transesterification step)|go:"GO:0000389"(mRNA 3'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000974"(Prp19 complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0071014"(post-mRNA release spliceosomal complex)|go:"GO:0071020"(post-spliceosomal complex)|interpro:IPR009360(Isy1-like splicing)|interpro:IPR029012|interpro:IPR037200|mint:Q9ULR0|rcsb pdb:5YZG|rcsb pdb:6FF7|rcsb pdb:6ZYM|rcsb pdb:7A5P|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-72163 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:DQKOCe+CcQ6mDGL+8bpeW0PGbe49606 rogid:t4QKu0uotUIJIzR8DTXWje21U1A9606 rigid:FymqM4gX+wzaAQJ9KmmmeMhJTCE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95072 uniprotkb:O95816 intact:EBI-9361206|uniprotkb:Q658V5|uniprotkb:Q6IA92|uniprotkb:D3DS62|uniprotkb:Q8WUV8|uniprotkb:A8K576|uniprotkb:Q9NVQ9|uniprotkb:Q9BTF2|ensembl:ENSP00000482439|ensembl:ENSP00000482546|ensembl:ENSP00000493523|ensembl:ENSP00000495458 intact:EBI-355275|uniprotkb:Q08AS9|uniprotkb:Q6FID0|uniprotkb:B4DXE2|ensembl:ENSP00000359727|intact:EBI-11068407 psi-mi:rec8_human(display_long)|uniprotkb:REC8(gene name)|psi-mi:REC8(display_short)|uniprotkb:Cohesin Rec8p(gene name synonym)|uniprotkb:REC8L1(gene name synonym) psi-mi:bag2_human(display_long)|uniprotkb:BAG2(gene name)|psi-mi:BAG2(display_short)|uniprotkb:Bcl-2-associated athanogene 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483697|imex:IM-26985-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041670.1|refseq:NP_005123.2|ensembl:ENSG00000100918(gene)|ensembl:ENSG00000285007(gene)|ensembl:ENST00000611366(transcript)|ensembl:ENST00000620473(transcript)|ensembl:ENST00000642486(transcript)|ensembl:ENST00000646765(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0009566"(fertilization)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|mint:O95072|reactome:R-HSA-1221632 refseq:NP_004273.1|refseq:XP_011513301.1|refseq:XP_005249547.1|ensembl:ENSG00000112208(gene)|ensembl:ENST00000370693(transcript)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0019538"(protein metabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1901588"(dendritic microtubule)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|mint:O95816|reactome:R-HSA-3371453|refseq:XP_011513300.1 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:DQKOCe+CcQ6mDGL+8bpeW0PGbe49606 rogid:nBGGBIQc/3P0mwp7N/XuTGLOrg89606 rigid:FymqM4gX+wzaAQJ9KmmmeMhJTCE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95072 uniprotkb:P51608 intact:EBI-9361206|uniprotkb:Q658V5|uniprotkb:Q6IA92|uniprotkb:D3DS62|uniprotkb:Q8WUV8|uniprotkb:A8K576|uniprotkb:Q9NVQ9|uniprotkb:Q9BTF2|ensembl:ENSP00000482439|ensembl:ENSP00000482546|ensembl:ENSP00000493523|ensembl:ENSP00000495458 intact:EBI-1189067|uniprotkb:O15233|uniprotkb:Q6QHH9|uniprotkb:Q7Z384|ensembl:ENSP00000301948 psi-mi:rec8_human(display_long)|uniprotkb:REC8(gene name)|psi-mi:REC8(display_short)|uniprotkb:Cohesin Rec8p(gene name synonym)|uniprotkb:REC8L1(gene name synonym) psi-mi:mecp2_human(display_long)|uniprotkb:MECP2(gene name)|psi-mi:MECP2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483697|imex:IM-26985-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041670.1|refseq:NP_005123.2|ensembl:ENSG00000100918(gene)|ensembl:ENSG00000285007(gene)|ensembl:ENST00000611366(transcript)|ensembl:ENST00000620473(transcript)|ensembl:ENST00000642486(transcript)|ensembl:ENST00000646765(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0009566"(fertilization)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|mint:O95072|reactome:R-HSA-1221632 refseq:NP_001104262.1|refseq:NP_004983.1|refseq:NP_001303266.1|ensembl:ENSG00000169057(gene)|ensembl:ENST00000303391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0001662"(behavioral fear response)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001964"(startle response)|go:"GO:0001976"(nervous system process involved in regulation of systemic arterial blood pressure)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006020"(inositol metabolic process)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006576"(cellular biogenic amine metabolic process)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007416"(synapse assembly)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0007616"(long-term memory)|go:"GO:0008104"(protein localization)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016358"(dendrite development)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016571"(histone methylation)|go:"GO:0016573"(histone acetylation)|go:"GO:0019230"(proprioception)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021591"(ventricular system development)|go:"GO:0032048"(cardiolipin metabolic process)|go:"GO:0035176"(social behavior)|go:"GO:0035197"(siRNA binding)|go:"GO:0042551"(neuron maturation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051151"(negative regulation of smooth muscle cell differentiation)|go:"GO:0051707"(response to other organism)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0098794"(postsynapse)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|go:"GO:1905643"(positive regulation of DNA methylation)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000820"(negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR017353(Methyl-CpG binding protein MeCP2)|mint:P51608|rcsb pdb:1QK9|rcsb pdb:3C2I|rcsb pdb:5BT2|rcsb pdb:6C1Y|rcsb pdb:6OGJ|rcsb pdb:6OGK|reactome:R-HSA-8986944|reactome:R-HSA-9022534|reactome:R-HSA-9022535|reactome:R-HSA-9022537|reactome:R-HSA-9022538|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9022702|reactome:R-HSA-9022707|reactome:R-HSA-9022927|dip:DIP-39983N - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:DQKOCe+CcQ6mDGL+8bpeW0PGbe49606 rogid:7c5ZZAZsqV7AciGN4hzFNWJLeUk9606 rigid:FymqM4gX+wzaAQJ9KmmmeMhJTCE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95072 uniprotkb:O75190 intact:EBI-9361206|uniprotkb:Q658V5|uniprotkb:Q6IA92|uniprotkb:D3DS62|uniprotkb:Q8WUV8|uniprotkb:A8K576|uniprotkb:Q9NVQ9|uniprotkb:Q9BTF2|ensembl:ENSP00000482439|ensembl:ENSP00000482546|ensembl:ENSP00000493523|ensembl:ENSP00000495458 intact:EBI-1053164|uniprotkb:A4D232|uniprotkb:O95806|uniprotkb:A8KAG0|uniprotkb:B4DN73|uniprotkb:E9PCZ2|uniprotkb:Q53EN8|uniprotkb:Q59EF2|uniprotkb:Q6FIC8|uniprotkb:Q75MA2|uniprotkb:Q9UIK6|uniprotkb:A8K7D8|ensembl:ENSP00000262177 psi-mi:rec8_human(display_long)|uniprotkb:REC8(gene name)|psi-mi:REC8(display_short)|uniprotkb:Cohesin Rec8p(gene name synonym)|uniprotkb:REC8L1(gene name synonym) psi-mi:dnjb6_human(display_long)|uniprotkb:Heat shock protein J2(gene name synonym)|uniprotkb:MSJ-1(gene name synonym)|uniprotkb:HHDJ1(gene name synonym)|uniprotkb:DNAJB6(gene name)|psi-mi:DNAJB6(display_short)|uniprotkb:HSJ2(gene name synonym)|uniprotkb:MSJ1(gene name synonym)|uniprotkb:MRJ(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483697|imex:IM-26985-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041670.1|refseq:NP_005123.2|ensembl:ENSG00000100918(gene)|ensembl:ENSG00000285007(gene)|ensembl:ENST00000611366(transcript)|ensembl:ENST00000620473(transcript)|ensembl:ENST00000642486(transcript)|ensembl:ENST00000646765(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0009566"(fertilization)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|mint:O95072|reactome:R-HSA-1221632 refseq:NP_005485.1|refseq:NP_490647.1|ensembl:ENSG00000105993(gene)|ensembl:ENST00000262177(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0060710"(chorio-allantoic fusion)|go:"GO:0060715"(syncytiotrophoblast cell differentiation involved in labyrinthine layer development)|go:"GO:0060717"(chorion development)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR018253|interpro:IPR036869|mint:O75190|rcsb pdb:6U3R|rcsb pdb:6U3S|rcsb pdb:7JSQ|reactome:R-HSA-3371453|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030198"(extracellular matrix organization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process) - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:DQKOCe+CcQ6mDGL+8bpeW0PGbe49606 rogid:6X99Uu2SBlHsGCv61ZbwSz4LRp89606 rigid:FymqM4gX+wzaAQJ9KmmmeMhJTCE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95072 uniprotkb:Q9UL15 intact:EBI-9361206|uniprotkb:Q658V5|uniprotkb:Q6IA92|uniprotkb:D3DS62|uniprotkb:Q8WUV8|uniprotkb:A8K576|uniprotkb:Q9NVQ9|uniprotkb:Q9BTF2|ensembl:ENSP00000482439|ensembl:ENSP00000482546|ensembl:ENSP00000493523|ensembl:ENSP00000495458 intact:EBI-356517|uniprotkb:O94950|uniprotkb:Q86W59|ensembl:ENSP00000299204|ensembl:ENSP00000391713 psi-mi:rec8_human(display_long)|uniprotkb:REC8(gene name)|psi-mi:REC8(display_short)|uniprotkb:Cohesin Rec8p(gene name synonym)|uniprotkb:REC8L1(gene name synonym) psi-mi:bag5_human(display_long)|uniprotkb:BAG5(gene name)|psi-mi:BAG5(display_short)|uniprotkb:KIAA0873(gene name synonym)|uniprotkb:Bcl-2-associated athanogene 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483697|imex:IM-26985-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041670.1|refseq:NP_005123.2|ensembl:ENSG00000100918(gene)|ensembl:ENSG00000285007(gene)|ensembl:ENST00000611366(transcript)|ensembl:ENST00000620473(transcript)|ensembl:ENST00000642486(transcript)|ensembl:ENST00000646765(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0009566"(fertilization)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|mint:O95072|reactome:R-HSA-1221632 refseq:NP_001015048.1|refseq:NP_001015049.1|refseq:NP_004864.1|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0061084"(negative regulation of protein refolding)|go:"GO:0070997"(neuron death)|go:"GO:0090083"(regulation of inclusion body assembly)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR036533|interpro:IPR039773|mint:Q9UL15|rcsb pdb:2D9D|rcsb pdb:3A8Y|reactome:R-HSA-3371453|go:"GO:0051438"(regulation of ubiquitin-protein transferase activity)|ensembl:ENSG00000166170(gene)|ensembl:ENST00000299204(transcript)|ensembl:ENST00000445922(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0007030"(Golgi organization)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|dip:DIP-53428N - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:DQKOCe+CcQ6mDGL+8bpeW0PGbe49606 rogid:I5E45kk4QcYF/BEa5qh7IBeBzF09606 rigid:FymqM4gX+wzaAQJ9KmmmeMhJTCE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95072 uniprotkb:Q9UNP9 intact:EBI-9361206|uniprotkb:Q658V5|uniprotkb:Q6IA92|uniprotkb:D3DS62|uniprotkb:Q8WUV8|uniprotkb:A8K576|uniprotkb:Q9NVQ9|uniprotkb:Q9BTF2|ensembl:ENSP00000482439|ensembl:ENSP00000482546|ensembl:ENSP00000493523|ensembl:ENSP00000495458 intact:EBI-591818|uniprotkb:Q3S611|uniprotkb:Q5TGA3|uniprotkb:O43634|uniprotkb:O43635|uniprotkb:Q32Q72|uniprotkb:Q5TGA0|uniprotkb:Q5TGA2|uniprotkb:Q9UIZ5|uniprotkb:B2R971|ensembl:ENSP00000312769 psi-mi:rec8_human(display_long)|uniprotkb:REC8(gene name)|psi-mi:REC8(display_short)|uniprotkb:Cohesin Rec8p(gene name synonym)|uniprotkb:REC8L1(gene name synonym) psi-mi:ppie_human(display_long)|uniprotkb:Cyclophilin E(gene name synonym)|uniprotkb:Cyclophilin-33(gene name synonym)|uniprotkb:PPIE(gene name)|psi-mi:PPIE(display_short)|uniprotkb:CYP33(gene name synonym)|uniprotkb:Rotamase E(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483697|imex:IM-26985-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041670.1|refseq:NP_005123.2|ensembl:ENSG00000100918(gene)|ensembl:ENSG00000285007(gene)|ensembl:ENST00000611366(transcript)|ensembl:ENST00000620473(transcript)|ensembl:ENST00000642486(transcript)|ensembl:ENST00000646765(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0009566"(fertilization)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|mint:O95072|reactome:R-HSA-1221632 refseq:NP_006103.1|refseq:NP_982281.1|refseq:NP_001181936.1|refseq:XP_016855540.1|dip:DIP-34757N|ensembl:ENSG00000084072(gene)|ensembl:ENST00000324379(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR016304(Peptidyl-prolyl cis-trans isomerase E)|interpro:IPR020892|interpro:IPR029000|interpro:IPR034168|interpro:IPR035979|mint:Q9UNP9|rcsb pdb:1ZMF|rcsb pdb:2CQB|rcsb pdb:2KU7|rcsb pdb:2KYX|rcsb pdb:2R99|rcsb pdb:3LPY|rcsb pdb:3MDF|rcsb pdb:3UCH|rcsb pdb:5MQF|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:7A5P|rcsb pdb:7ABI|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6798695|reactome:R-HSA-72163 - - comment:"author score: 142" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:DQKOCe+CcQ6mDGL+8bpeW0PGbe49606 rogid:zMkadgyIl5RwvoD3h3vetTqLjg49606 rigid:FymqM4gX+wzaAQJ9KmmmeMhJTCE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95072 uniprotkb:Q9UQE7 intact:EBI-9361206|uniprotkb:Q658V5|uniprotkb:Q6IA92|uniprotkb:D3DS62|uniprotkb:Q8WUV8|uniprotkb:A8K576|uniprotkb:Q9NVQ9|uniprotkb:Q9BTF2|ensembl:ENSP00000482439|ensembl:ENSP00000482546|ensembl:ENSP00000493523|ensembl:ENSP00000495458 intact:EBI-80718|ensembl:ENSP00000354720|uniprotkb:O60464|uniprotkb:Q5T482|uniprotkb:A8K156 psi-mi:rec8_human(display_long)|uniprotkb:REC8(gene name)|psi-mi:REC8(display_short)|uniprotkb:Cohesin Rec8p(gene name synonym)|uniprotkb:REC8L1(gene name synonym) psi-mi:smc3_human(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:BAM(gene name synonym)|uniprotkb:SMC3L1(gene name synonym)|uniprotkb:Chondroitin sulfate proteoglycan 6(gene name synonym)|uniprotkb:Chromosome-associated polypeptide(gene name synonym)|uniprotkb:Basement membrane-associated chondroitin proteoglycan(gene name synonym)|uniprotkb:BMH(gene name synonym)|uniprotkb:CSPG6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483697|imex:IM-26985-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041670.1|refseq:NP_005123.2|ensembl:ENSG00000100918(gene)|ensembl:ENSG00000285007(gene)|ensembl:ENST00000611366(transcript)|ensembl:ENST00000620473(transcript)|ensembl:ENST00000642486(transcript)|ensembl:ENST00000646765(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0009566"(fertilization)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|mint:O95072|reactome:R-HSA-1221632 go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|mint:Q9UQE7|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0070840"(dynein complex binding)|ensembl:ENSG00000108055(gene)|ensembl:ENST00000361804(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|refseq:NP_005436.1|dip:DIP-29200N - - comment:"author score: 180" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:DQKOCe+CcQ6mDGL+8bpeW0PGbe49606 rogid:pUxr+sTtttRzGlqCRz/25woNtrg9606 rigid:FymqM4gX+wzaAQJ9KmmmeMhJTCE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95072 uniprotkb:Q14683 intact:EBI-9361206|uniprotkb:Q658V5|uniprotkb:Q6IA92|uniprotkb:D3DS62|uniprotkb:Q8WUV8|uniprotkb:A8K576|uniprotkb:Q9NVQ9|uniprotkb:Q9BTF2|ensembl:ENSP00000482439|ensembl:ENSP00000482546|ensembl:ENSP00000493523|ensembl:ENSP00000495458 intact:EBI-80690|ensembl:ENSP00000323421|uniprotkb:O14995|uniprotkb:Q16351|uniprotkb:Q2M228 psi-mi:rec8_human(display_long)|uniprotkb:REC8(gene name)|psi-mi:REC8(display_short)|uniprotkb:Cohesin Rec8p(gene name synonym)|uniprotkb:REC8L1(gene name synonym) psi-mi:smc1a_human(display_long)|uniprotkb:SMC1A(gene name)|psi-mi:SMC1A(display_short)|uniprotkb:DXS423E(gene name synonym)|uniprotkb:KIAA0178(gene name synonym)|uniprotkb:SB1.8(gene name synonym)|uniprotkb:SMC1(gene name synonym)|uniprotkb:SMC1L1(gene name synonym)|uniprotkb:Sb1.8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483697|imex:IM-26985-49 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001041670.1|refseq:NP_005123.2|ensembl:ENSG00000100918(gene)|ensembl:ENSG00000285007(gene)|ensembl:ENST00000611366(transcript)|ensembl:ENST00000620473(transcript)|ensembl:ENST00000642486(transcript)|ensembl:ENST00000646765(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000800"(lateral element)|go:"GO:0001556"(oocyte maturation)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0007141"(male meiosis I)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007286"(spermatid development)|go:"GO:0009566"(fertilization)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0051177"(meiotic sister chromatid cohesion)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|mint:O95072|reactome:R-HSA-1221632 ensembl:ENSG00000072501(gene)|ensembl:ENST00000322213(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0009314"(response to radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR029683|interpro:IPR036277|mint:Q14683|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|reactome:R-HSA-2468052|refseq:NP_006297.2|dip:DIP-30911N - - comment:"author score: 185" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:DQKOCe+CcQ6mDGL+8bpeW0PGbe49606 rogid:0UhfA7txIetlcGvSes6d+Bv1ZdY9606 rigid:FymqM4gX+wzaAQJ9KmmmeMhJTCE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01826 uniprotkb:Q9UPW6 intact:EBI-743747|uniprotkb:C9JTR6|uniprotkb:B3KXF1|uniprotkb:Q59EQ0|intact:EBI-28974629|ensembl:ENSP00000341024|ensembl:ENSP00000399708 intact:EBI-8298169|ensembl:ENSP00000260926|ensembl:ENSP00000401112|ensembl:ENSP00000405420|uniprotkb:Q3ZB87|uniprotkb:Q4V763|intact:MINT-2822679|uniprotkb:A8K5Z8 psi-mi:satb1_human(display_long)|uniprotkb:Special AT-rich sequence-binding protein 1(gene name synonym)|uniprotkb:SATB1(gene name)|psi-mi:SATB1(display_short) psi-mi:satb2_human(display_long)|uniprotkb:SATB2(gene name)|psi-mi:SATB2(display_short)|uniprotkb:KIAA1034(gene name synonym)|uniprotkb:Special AT-rich sequence-binding protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484276|imex:IM-26985-435 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000341024|ensembl:ENST00000417717|ensembl:ENSP00000399518|ensembl:ENSP00000399708|refseq:NP_001124482.1|refseq:NP_001182399.1|refseq:NP_002962.1|refseq:NP_001309801.1|refseq:NP_001309802.1|refseq:NP_001309803.1|refseq:NP_001309804.1|refseq:NP_001309800.1|refseq:XP_011532290.1|refseq:XP_011532291.1|dip:DIP-48757N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003350(Homeodomain protein CUT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR032355|interpro:IPR032392|interpro:IPR038216|interpro:IPR038224|interpro:IPR039673|mint:Q01826|rcsb pdb:1YSE|rcsb pdb:2L1P|rcsb pdb:2MW8|rcsb pdb:2O49|rcsb pdb:2O4A|rcsb pdb:3NZL|rcsb pdb:3TUO|rcsb pdb:6LFF|reactome:R-HSA-111465|reactome:R-HSA-4551638|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|ensembl:ENSG00000182568(gene)|ensembl:ENST00000338745(transcript)|ensembl:ENST00000454909(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin) ensembl:ENSG00000119042(gene)|ensembl:ENST00000260926(transcript)|ensembl:ENST00000417098(transcript)|ensembl:ENST00000457245(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002076"(osteoblast development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021902"(commitment of neuronal cell to specific neuron type in forebrain)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071310"(cellular response to organic substance)|interpro:IPR001356(Homeobox)|interpro:IPR003350(Homeodomain protein CUT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR032355|interpro:IPR032392|interpro:IPR038216|interpro:IPR038224|interpro:IPR039673|mint:Q9UPW6|rcsb pdb:1WI3|rcsb pdb:1WIZ|rcsb pdb:2CSF|reactome:R-HSA-4551638|reactome:R-HSA-8940973|refseq:XP_011509142.1|refseq:XP_006712435.1|refseq:NP_001165988.1|refseq:NP_001165980.1|refseq:NP_056080.1|dip:DIP-60551N - - comment:mint|function:May play an important role in palate formation|function:"Chromosomal aberrations involving SATB2 are found in isolated cleft palate. Translocation t(2;7); translocation t(2;11)"|function:"Defects in SATB2 are the cause of isolated cleft palate with mental retardation [MIM:119540]. Patients manifest cleft palate, craniofacial dysmorphism and profound mental retardation"|comment:"author score: 41" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xR1uXIoTJqiU6vzeM9h8AccM8fc9606 rogid:/dQFGKi08prg2Xjhsj4sqW77Cl09606 rigid:0Gh8MtHG0EI66nVOQ/uCwHvFlGs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01826 uniprotkb:Q07955 intact:EBI-743747|uniprotkb:C9JTR6|uniprotkb:B3KXF1|uniprotkb:Q59EQ0|intact:EBI-28974629|ensembl:ENSP00000341024|ensembl:ENSP00000399708 intact:EBI-398920|uniprotkb:Q13809|uniprotkb:B2R6Z7|uniprotkb:D3DTZ3|ensembl:ENSP00000258962 psi-mi:satb1_human(display_long)|uniprotkb:Special AT-rich sequence-binding protein 1(gene name synonym)|uniprotkb:SATB1(gene name)|psi-mi:SATB1(display_short) psi-mi:srsf1_human(display_long)|uniprotkb:SF2(gene name synonym)|uniprotkb:SF2P33(gene name synonym)|uniprotkb:OK/SW-cl.3(orf name)|uniprotkb:SRSF1(gene name)|psi-mi:SRSF1(display_short)|uniprotkb:ASF(gene name synonym)|uniprotkb:pre-mRNA-splicing factor SF2, P33 subunit(gene name synonym)|uniprotkb:Alternative-splicing factor 1(gene name synonym)|uniprotkb:SFRS1(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484276|imex:IM-26985-435 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000341024|ensembl:ENST00000417717|ensembl:ENSP00000399518|ensembl:ENSP00000399708|refseq:NP_001124482.1|refseq:NP_001182399.1|refseq:NP_002962.1|refseq:NP_001309801.1|refseq:NP_001309802.1|refseq:NP_001309803.1|refseq:NP_001309804.1|refseq:NP_001309800.1|refseq:XP_011532290.1|refseq:XP_011532291.1|dip:DIP-48757N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003350(Homeodomain protein CUT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR032355|interpro:IPR032392|interpro:IPR038216|interpro:IPR038224|interpro:IPR039673|mint:Q01826|rcsb pdb:1YSE|rcsb pdb:2L1P|rcsb pdb:2MW8|rcsb pdb:2O49|rcsb pdb:2O4A|rcsb pdb:3NZL|rcsb pdb:3TUO|rcsb pdb:6LFF|reactome:R-HSA-111465|reactome:R-HSA-4551638|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|ensembl:ENSG00000182568(gene)|ensembl:ENST00000338745(transcript)|ensembl:ENST00000454909(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin) refseq:NP_001071634.1|refseq:NP_008855.1|dip:DIP-2155N|ensembl:ENSG00000136450(gene)|ensembl:ENST00000258962(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0051028"(mRNA transport)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097421"(liver regeneration)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034520|interpro:IPR035979|mint:Q07955|rcsb pdb:2M7S|rcsb pdb:2M8D|rcsb pdb:2O3D|rcsb pdb:3BEG|rcsb pdb:4C0O|rcsb pdb:6HPJ|rcsb pdb:7ABG|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:1X4A - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xR1uXIoTJqiU6vzeM9h8AccM8fc9606 rogid:6/IA4a3btkfSBtMH32iCe+rqZ8Y9606 rigid:0Gh8MtHG0EI66nVOQ/uCwHvFlGs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01826 uniprotkb:O94903 intact:EBI-743747|uniprotkb:C9JTR6|uniprotkb:B3KXF1|uniprotkb:Q59EQ0|intact:EBI-28974629|ensembl:ENSP00000341024|ensembl:ENSP00000399708 intact:EBI-2860631|uniprotkb:Q6FI94|ensembl:ENSP00000333551 psi-mi:satb1_human(display_long)|uniprotkb:Special AT-rich sequence-binding protein 1(gene name synonym)|uniprotkb:SATB1(gene name)|psi-mi:SATB1(display_short) psi-mi:plphp_human(display_long)|uniprotkb:PLPBP(gene name)|psi-mi:PLPBP(display_short)|uniprotkb:PROSC(gene name synonym)|uniprotkb:Proline synthase co-transcribed bacterial homolog protein(gene name synonym)|uniprotkb:Pyridoxal phosphate-binding protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484276|imex:IM-26985-435 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000341024|ensembl:ENST00000417717|ensembl:ENSP00000399518|ensembl:ENSP00000399708|refseq:NP_001124482.1|refseq:NP_001182399.1|refseq:NP_002962.1|refseq:NP_001309801.1|refseq:NP_001309802.1|refseq:NP_001309803.1|refseq:NP_001309804.1|refseq:NP_001309800.1|refseq:XP_011532290.1|refseq:XP_011532291.1|dip:DIP-48757N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003350(Homeodomain protein CUT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR032355|interpro:IPR032392|interpro:IPR038216|interpro:IPR038224|interpro:IPR039673|mint:Q01826|rcsb pdb:1YSE|rcsb pdb:2L1P|rcsb pdb:2MW8|rcsb pdb:2O49|rcsb pdb:2O4A|rcsb pdb:3NZL|rcsb pdb:3TUO|rcsb pdb:6LFF|reactome:R-HSA-111465|reactome:R-HSA-4551638|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|ensembl:ENSG00000182568(gene)|ensembl:ENST00000338745(transcript)|ensembl:ENST00000454909(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin) refseq:NP_009129.1|ensembl:ENSG00000147471(gene)|ensembl:ENST00000328195(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030170"(pyridoxal phosphate binding)|interpro:IPR001608(Alanine racemase, N-terminal)|interpro:IPR011078(Predicted pyridoxal phosphate-dependent enzyme, YBL036C type)|interpro:IPR029066|mint:O94903 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xR1uXIoTJqiU6vzeM9h8AccM8fc9606 rogid:xrOEPMjG0y+otG21Al6Q0UuQcEY9606 rigid:0Gh8MtHG0EI66nVOQ/uCwHvFlGs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01826 uniprotkb:P35030 intact:EBI-743747|uniprotkb:C9JTR6|uniprotkb:B3KXF1|uniprotkb:Q59EQ0|intact:EBI-28974629|ensembl:ENSP00000341024|ensembl:ENSP00000399708 intact:EBI-1221209|uniprotkb:Q5VXV0|intact:EBI-2825937|uniprotkb:A8CED3|uniprotkb:F8W7P3|uniprotkb:Q6ISJ4|uniprotkb:P15951|uniprotkb:Q15665|uniprotkb:Q9UQV3|uniprotkb:A9Z1Y4|uniprotkb:E7ES07|uniprotkb:A8CED1 psi-mi:satb1_human(display_long)|uniprotkb:Special AT-rich sequence-binding protein 1(gene name synonym)|uniprotkb:SATB1(gene name)|psi-mi:SATB1(display_short) psi-mi:try3_human(display_long)|uniprotkb:PRSS3(gene name)|psi-mi:PRSS3(display_short)|uniprotkb:PRSS4(gene name synonym)|uniprotkb:TRY3(gene name synonym)|uniprotkb:TRY4(gene name synonym)|uniprotkb:Trypsin III(gene name synonym)|uniprotkb:Brain trypsinogen(gene name synonym)|uniprotkb:Mesotrypsinogen(gene name synonym)|uniprotkb:Trypsin IV(gene name synonym)|uniprotkb:Serine protease 3(gene name synonym)|uniprotkb:Serine protease 4(gene name synonym)|uniprotkb:Mesotrypsin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484276|imex:IM-26985-435 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000341024|ensembl:ENST00000417717|ensembl:ENSP00000399518|ensembl:ENSP00000399708|refseq:NP_001124482.1|refseq:NP_001182399.1|refseq:NP_002962.1|refseq:NP_001309801.1|refseq:NP_001309802.1|refseq:NP_001309803.1|refseq:NP_001309804.1|refseq:NP_001309800.1|refseq:XP_011532290.1|refseq:XP_011532291.1|dip:DIP-48757N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003350(Homeodomain protein CUT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR032355|interpro:IPR032392|interpro:IPR038216|interpro:IPR038224|interpro:IPR039673|mint:Q01826|rcsb pdb:1YSE|rcsb pdb:2L1P|rcsb pdb:2MW8|rcsb pdb:2O49|rcsb pdb:2O4A|rcsb pdb:3NZL|rcsb pdb:3TUO|rcsb pdb:6LFF|reactome:R-HSA-111465|reactome:R-HSA-4551638|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|ensembl:ENSG00000182568(gene)|ensembl:ENST00000338745(transcript)|ensembl:ENST00000454909(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin) refseq:NP_002762.2|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|refseq:NP_001184026.2|refseq:NP_031369.2|refseq:NP_001184027.1|mint:P35030|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0007586"(digestion)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0031638"(zymogen activation)|go:"GO:0043542"(endothelial cell migration)|go:"GO:1904724"(tertiary granule lumen)|rcsb pdb:1H4W|rcsb pdb:2R9P|rcsb pdb:3L33|rcsb pdb:3L3T|rcsb pdb:3P92|rcsb pdb:3P95|rcsb pdb:4DG4|rcsb pdb:4U30|rcsb pdb:4U32|rcsb pdb:5C67|rcsb pdb:5JBT|rcsb pdb:5TP0|rcsb pdb:6BX8|rcsb pdb:6GFI|reactome:R-HSA-1462054|reactome:R-HSA-196741|reactome:R-HSA-6798695|reactome:R-HSA-6803157|interpro:IPR043504 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xR1uXIoTJqiU6vzeM9h8AccM8fc9606 rogid:AEfz7orXeNoasizB5N76AkF4WMk9606 rigid:0Gh8MtHG0EI66nVOQ/uCwHvFlGs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01826 uniprotkb:Q96LD4 intact:EBI-743747|uniprotkb:C9JTR6|uniprotkb:B3KXF1|uniprotkb:Q59EQ0|intact:EBI-28974629|ensembl:ENSP00000341024|ensembl:ENSP00000399708 intact:EBI-2130423|uniprotkb:Q96GU5|uniprotkb:Q9BRN7|uniprotkb:Q96AD0|intact:EBI-28987808|ensembl:ENSP00000254816 psi-mi:satb1_human(display_long)|uniprotkb:Special AT-rich sequence-binding protein 1(gene name synonym)|uniprotkb:SATB1(gene name)|psi-mi:SATB1(display_short) psi-mi:tri47_human(display_long)|uniprotkb:TRIM47(gene name)|psi-mi:TRIM47(display_short)|uniprotkb:GOA(gene name synonym)|uniprotkb:RNF100(gene name synonym)|uniprotkb:Gene overexpressed in astrocytoma protein(gene name synonym)|uniprotkb:RING finger protein 100(gene name synonym)|uniprotkb:Tripartite motif-containing protein 47(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484276|imex:IM-26985-435 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000341024|ensembl:ENST00000417717|ensembl:ENSP00000399518|ensembl:ENSP00000399708|refseq:NP_001124482.1|refseq:NP_001182399.1|refseq:NP_002962.1|refseq:NP_001309801.1|refseq:NP_001309802.1|refseq:NP_001309803.1|refseq:NP_001309804.1|refseq:NP_001309800.1|refseq:XP_011532290.1|refseq:XP_011532291.1|dip:DIP-48757N|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR003350(Homeodomain protein CUT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR032355|interpro:IPR032392|interpro:IPR038216|interpro:IPR038224|interpro:IPR039673|mint:Q01826|rcsb pdb:1YSE|rcsb pdb:2L1P|rcsb pdb:2MW8|rcsb pdb:2O49|rcsb pdb:2O4A|rcsb pdb:3NZL|rcsb pdb:3TUO|rcsb pdb:6LFF|reactome:R-HSA-111465|reactome:R-HSA-4551638|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|ensembl:ENSG00000182568(gene)|ensembl:ENST00000338745(transcript)|ensembl:ENST00000454909(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin) refseq:NP_258411.2|ensembl:ENSP00000254816|refseq:XP_005257844.1|refseq:XP_005257845.1|ensembl:ENSG00000132481(gene)|ensembl:ENST00000254816(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR042780|interpro:IPR043136|mint:Q96LD4 - - comment:"author score: 33" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xR1uXIoTJqiU6vzeM9h8AccM8fc9606 rogid:F8KSNivuNkLAEFW/DrYsMu5ICRk9606 rigid:0Gh8MtHG0EI66nVOQ/uCwHvFlGs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXW5 uniprotkb:P22528 intact:EBI-395878|uniprotkb:Q49AS7|uniprotkb:Q9H8Y2|ensembl:ENSP00000476948|uniprotkb:C9JKB5 intact:EBI-1058892|ensembl:ENSP00000306461|uniprotkb:B2R5H7|uniprotkb:P22529|uniprotkb:P22530|uniprotkb:Q5T524 psi-mi:rpap2_human(display_long)|uniprotkb:RPAP2(gene name)|psi-mi:RPAP2(display_short)|uniprotkb:C1orf82(gene name synonym)|uniprotkb:RNA polymerase II-associated protein 2(gene name synonym) psi-mi:spr1b_human(display_long)|uniprotkb:SPRR1B(gene name)|psi-mi:SPRR1B(display_short)|uniprotkb:Small proline-rich protein IB(gene name synonym)|uniprotkb:14.9 kDa pancornulin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484015|imex:IM-26985-575 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079089.2|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008420"(RNA polymerase II CTD heptapeptide repeat phosphatase activity)|go:"GO:0009301"(snRNA transcription)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0043175"(RNA polymerase core enzyme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR007308(Protein of unknown function DUF408)|interpro:IPR038534|interpro:IPR039693|mint:Q8IXW5|rcsb pdb:7B7U|reactome:R-HSA-6807505|ensembl:ENSG00000122484(gene)|ensembl:ENST00000610020(transcript)|go:"GO:0005634"(nucleus)|dip:DIP-32939N ensembl:ENSG00000169469(gene)|ensembl:ENST00000307098(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0031424"(keratinization)|interpro:IPR003302("Cornifin (SPRR)")|mint:P22528|reactome:R-HSA-6809371|refseq:NP_003116.2 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:niEFEvqkASycxkzfe9TYJuerUuY9606 rogid:WU0vu+DHdIJm0x40HdcpAdJgdgo9606 rigid:4Es/eEJhQjCnFla54muNKErTv7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXW5 uniprotkb:Q9UHW5 intact:EBI-395878|uniprotkb:Q49AS7|uniprotkb:Q9H8Y2|ensembl:ENSP00000476948|uniprotkb:C9JKB5 intact:EBI-395491|uniprotkb:Q53FS3|uniprotkb:Q6UVZ6|uniprotkb:Q7Z3D3|uniprotkb:Q8NEI2|uniprotkb:Q96HK9|uniprotkb:B2RC54|uniprotkb:D4YWV1|ensembl:ENSP00000228827|uniprotkb:F5H759 psi-mi:rpap2_human(display_long)|uniprotkb:RPAP2(gene name)|psi-mi:RPAP2(display_short)|uniprotkb:C1orf82(gene name synonym)|uniprotkb:RNA polymerase II-associated protein 2(gene name synonym) psi-mi:gpn3_human(display_long)|uniprotkb:ATPBD1C(gene name synonym)|uniprotkb:ATP-binding domain 1 family member C(gene name synonym)|uniprotkb:GPN3(gene name)|psi-mi:GPN3(display_short)|uniprotkb:AD-009(orf name)|uniprotkb:UNQ1876/PRO4319(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484015|imex:IM-26985-575 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079089.2|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008420"(RNA polymerase II CTD heptapeptide repeat phosphatase activity)|go:"GO:0009301"(snRNA transcription)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0043175"(RNA polymerase core enzyme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR007308(Protein of unknown function DUF408)|interpro:IPR038534|interpro:IPR039693|mint:Q8IXW5|rcsb pdb:7B7U|reactome:R-HSA-6807505|ensembl:ENSG00000122484(gene)|ensembl:ENST00000610020(transcript)|go:"GO:0005634"(nucleus)|dip:DIP-32939N refseq:NP_001157844.1|refseq:NP_001157845.1|refseq:NP_057385.3|ensembl:ENSG00000111231(gene)|ensembl:ENST00000228827(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0032991"(protein-containing complex)|interpro:IPR004130(Protein of unknown function, ATP binding)|interpro:IPR027417|interpro:IPR030228|mint:Q9UHW5 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:niEFEvqkASycxkzfe9TYJuerUuY9606 rogid:fKBsnLcvitaM76zQUW+MQXDPxTA9606 rigid:4Es/eEJhQjCnFla54muNKErTv7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXW5 uniprotkb:P02656 intact:EBI-395878|uniprotkb:Q49AS7|uniprotkb:Q9H8Y2|ensembl:ENSP00000476948|uniprotkb:C9JKB5 intact:EBI-1220113|uniprotkb:Q08E83|uniprotkb:Q6Q786|ensembl:ENSP00000227667 psi-mi:rpap2_human(display_long)|uniprotkb:RPAP2(gene name)|psi-mi:RPAP2(display_short)|uniprotkb:C1orf82(gene name synonym)|uniprotkb:RNA polymerase II-associated protein 2(gene name synonym) psi-mi:apoc3_human(display_long)|uniprotkb:APOC3(gene name)|psi-mi:APOC3(display_short)|uniprotkb:Apolipoprotein C3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484015|imex:IM-26985-575 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079089.2|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008420"(RNA polymerase II CTD heptapeptide repeat phosphatase activity)|go:"GO:0009301"(snRNA transcription)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0043175"(RNA polymerase core enzyme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR007308(Protein of unknown function DUF408)|interpro:IPR038534|interpro:IPR039693|mint:Q8IXW5|rcsb pdb:7B7U|reactome:R-HSA-6807505|ensembl:ENSG00000122484(gene)|ensembl:ENST00000610020(transcript)|go:"GO:0005634"(nucleus)|dip:DIP-32939N refseq:NP_000031.1|ensembl:ENSG00000110245(gene)|ensembl:ENST00000227667(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005769"(early endosome)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010897"(negative regulation of triglyceride catabolic process)|go:"GO:0010903"(negative regulation of very-low-density lipoprotein particle remodeling)|go:"GO:0010916"(negative regulation of very-low-density lipoprotein particle clearance)|go:"GO:0010987"(negative regulation of high-density lipoprotein particle clearance)|go:"GO:0010989"(negative regulation of low-density lipoprotein particle clearance)|go:"GO:0015485"(cholesterol binding)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034363"(intermediate-density lipoprotein particle)|go:"GO:0034366"(spherical high-density lipoprotein particle)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:0034382"(chylomicron remnant clearance)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0045833"(negative regulation of lipid metabolic process)|go:"GO:0048261"(negative regulation of receptor-mediated endocytosis)|go:"GO:0050995"(negative regulation of lipid catabolic process)|go:"GO:0051005"(negative regulation of lipoprotein lipase activity)|go:"GO:0055102"(lipase inhibitor activity)|go:"GO:0060621"(negative regulation of cholesterol import)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070653"(high-density lipoprotein particle receptor binding)|interpro:IPR008403(Apolipoprotein CIII)|interpro:IPR038195|mint:P02656|rcsb pdb:2JQ3|reactome:R-HSA-8963888|reactome:R-HSA-8963901|reactome:R-HSA-8964058|reactome:R-HSA-975634 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:niEFEvqkASycxkzfe9TYJuerUuY9606 rogid:DDj33pQWDh0i5+mwMy16Dmg6JPg9606 rigid:4Es/eEJhQjCnFla54muNKErTv7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXW5 uniprotkb:Q9HCN4 intact:EBI-395878|uniprotkb:Q49AS7|uniprotkb:Q9H8Y2|ensembl:ENSP00000476948|uniprotkb:C9JKB5 intact:EBI-745137|uniprotkb:O76004|uniprotkb:B4DQJ5|uniprotkb:B4DXU4|uniprotkb:B4DQM4|ensembl:ENSP00000476446|uniprotkb:B5MBZ5 psi-mi:rpap2_human(display_long)|uniprotkb:RPAP2(gene name)|psi-mi:RPAP2(display_short)|uniprotkb:C1orf82(gene name synonym)|uniprotkb:RNA polymerase II-associated protein 2(gene name synonym) psi-mi:gpn1_human(display_long)|uniprotkb:XAB1(gene name synonym)|uniprotkb:XPA-binding protein 1(gene name synonym)|uniprotkb:MBD2-interacting protein(gene name synonym)|uniprotkb:GPN1(gene name)|psi-mi:GPN1(display_short)|uniprotkb:MBDIN(gene name synonym)|uniprotkb:HUSSY-23(orf name)|uniprotkb:RNAPII-associated protein 4(gene name synonym)|uniprotkb:RPAP4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484015|imex:IM-26985-575 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079089.2|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008420"(RNA polymerase II CTD heptapeptide repeat phosphatase activity)|go:"GO:0009301"(snRNA transcription)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0043175"(RNA polymerase core enzyme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR007308(Protein of unknown function DUF408)|interpro:IPR038534|interpro:IPR039693|mint:Q8IXW5|rcsb pdb:7B7U|reactome:R-HSA-6807505|ensembl:ENSG00000122484(gene)|ensembl:ENST00000610020(transcript)|go:"GO:0005634"(nucleus)|dip:DIP-32939N refseq:NP_001138519.1|refseq:NP_001138520.1|refseq:NP_001138521.1|refseq:NP_009197.2|ensembl:ENSG00000198522(gene)|ensembl:ENST00000610189(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR004130(Protein of unknown function, ATP binding)|interpro:IPR027417|interpro:IPR030230|mint:Q9HCN4 - - comment:"author score: 33" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:niEFEvqkASycxkzfe9TYJuerUuY9606 rogid:QZOTFh9d1hOcoG1DxAueYEwbOpc9606 rigid:4Es/eEJhQjCnFla54muNKErTv7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXW5 uniprotkb:Q15648 intact:EBI-395878|uniprotkb:Q49AS7|uniprotkb:Q9H8Y2|ensembl:ENSP00000476948|uniprotkb:C9JKB5 intact:EBI-394459|uniprotkb:A2RRQ6|uniprotkb:O43810|uniprotkb:O75447|uniprotkb:Q6P9H7|uniprotkb:Q6PK58|uniprotkb:Q9HD39|ensembl:ENSP00000300651 psi-mi:rpap2_human(display_long)|uniprotkb:RPAP2(gene name)|psi-mi:RPAP2(display_short)|uniprotkb:C1orf82(gene name synonym)|uniprotkb:RNA polymerase II-associated protein 2(gene name synonym) psi-mi:med1_human(display_long)|uniprotkb:TRIP2(gene name synonym)|uniprotkb:MED1(gene name)|psi-mi:MED1(display_short)|uniprotkb:ARC205(gene name synonym)|uniprotkb:DRIP205(gene name synonym)|uniprotkb:TRAP220(gene name synonym)|uniprotkb:Activator-recruited cofactor 205 kDa component(gene name synonym)|uniprotkb:Mediator complex subunit 1(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-binding protein(gene name synonym)|uniprotkb:Thyroid hormone receptor-associated protein complex 220 kDa component(gene name synonym)|uniprotkb:Thyroid receptor-interacting protein 2(gene name synonym)|uniprotkb:p53 regulatory protein RB18A(gene name synonym)|uniprotkb:Vitamin D receptor-interacting protein complex component DRIP205(gene name synonym)|uniprotkb:CRSP1(gene name synonym)|uniprotkb:CRSP200(gene name synonym)|uniprotkb:DRIP230(gene name synonym)|uniprotkb:PBP(gene name synonym)|uniprotkb:PPARBP(gene name synonym)|uniprotkb:PPARGBP(gene name synonym)|uniprotkb:RB18A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484015|imex:IM-26985-575 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079089.2|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008420"(RNA polymerase II CTD heptapeptide repeat phosphatase activity)|go:"GO:0009301"(snRNA transcription)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0043175"(RNA polymerase core enzyme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR007308(Protein of unknown function DUF408)|interpro:IPR038534|interpro:IPR039693|mint:Q8IXW5|rcsb pdb:7B7U|reactome:R-HSA-6807505|ensembl:ENSG00000122484(gene)|ensembl:ENST00000610020(transcript)|go:"GO:0005634"(nucleus)|dip:DIP-32939N refseq:NP_004765.2|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060744"(mammary gland branching involved in thelarche)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0060750"(epithelial cell proliferation involved in mammary gland duct elongation)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070318"(positive regulation of G0 to G1 transition)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071383"(cellular response to steroid hormone stimulus)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001141"(regulation of RNA biosynthetic process)|interpro:IPR019680|mint:Q15648|rcsb pdb:1RJK|rcsb pdb:1RK3|rcsb pdb:1RKG|rcsb pdb:1RKH|rcsb pdb:2O4J|rcsb pdb:2O4R|rcsb pdb:2ZFX|rcsb pdb:3A2H|rcsb pdb:3AUN|rcsb pdb:3VJS|rcsb pdb:3VJT|rcsb pdb:3VRT|rcsb pdb:3VRU|rcsb pdb:3VRV|rcsb pdb:3VRW|rcsb pdb:3W0G|rcsb pdb:3W0H|rcsb pdb:3W0I|rcsb pdb:3W0J|rcsb pdb:3W5P|rcsb pdb:3W5Q|rcsb pdb:3W5R|rcsb pdb:3W5T|rcsb pdb:3WT5|rcsb pdb:3WT6|rcsb pdb:3WT7|rcsb pdb:3WTQ|rcsb pdb:4YNK|rcsb pdb:5AWJ|rcsb pdb:5AWK|rcsb pdb:5B41|rcsb pdb:5B5B|rcsb pdb:5GIC|rcsb pdb:5GID|rcsb pdb:5GIE|rcsb pdb:5XPM|rcsb pdb:5XPN|rcsb pdb:5XPO|rcsb pdb:5XPP|rcsb pdb:5XUQ|rcsb pdb:5XZF|rcsb pdb:5XZH|rcsb pdb:5ZWE|rcsb pdb:5ZWF|rcsb pdb:5ZWH|rcsb pdb:5ZWI|rcsb pdb:6D94|rcsb pdb:6JEZ|rcsb pdb:6K5O|rcsb pdb:6ONJ|rcsb pdb:7C7V|rcsb pdb:7C7W|rcsb pdb:7EMF|rcsb pdb:7ENA|rcsb pdb:7ENC|rcsb pdb:7ENJ|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-212436|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-383280|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-9018519|reactome:R-HSA-9707564|reactome:R-HSA-9707616|ensembl:ENSG00000125686(gene)|ensembl:ENST00000300651(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001889"(liver development)|go:"GO:0001892"(embryonic placenta development)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0002154"(thyroid hormone mediated signaling pathway)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003406"(retinal pigment epithelium development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0007595"(lactation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016592"(mediator complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030518"(intracellular steroid hormone receptor signaling pathway)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0035357"(peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042809"(vitamin D receptor binding)|go:"GO:0042974"(retinoic acid receptor binding)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0048822"(enucleate erythrocyte development)|go:"GO:0050693"(LBD domain binding)|dip:DIP-24212N - - comment:"author score: 33" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:niEFEvqkASycxkzfe9TYJuerUuY9606 rogid:A4EIAri9zYycSlTA7s6NzbOi9n49606 rigid:4Es/eEJhQjCnFla54muNKErTv7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXW5 uniprotkb:Q5VT52 intact:EBI-395878|uniprotkb:Q49AS7|uniprotkb:Q9H8Y2|ensembl:ENSP00000476948|uniprotkb:C9JKB5 intact:EBI-372367|uniprotkb:O75048|uniprotkb:Q5VT53|uniprotkb:Q6MZL4|uniprotkb:Q86XD2|uniprotkb:A8K6N8|uniprotkb:B3KPT1|uniprotkb:Q5VT51|uniprotkb:Q9P0D7|uniprotkb:B4E2Q6|ensembl:ENSP00000358064 psi-mi:rpap2_human(display_long)|uniprotkb:RPAP2(gene name)|psi-mi:RPAP2(display_short)|uniprotkb:C1orf82(gene name synonym)|uniprotkb:RNA polymerase II-associated protein 2(gene name synonym) psi-mi:rprd2_human(display_long)|uniprotkb:RPRD2(gene name)|psi-mi:RPRD2(display_short)|uniprotkb:KIAA0460(gene name synonym)|uniprotkb:HSPC099(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484015|imex:IM-26985-575 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079089.2|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008420"(RNA polymerase II CTD heptapeptide repeat phosphatase activity)|go:"GO:0009301"(snRNA transcription)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0043175"(RNA polymerase core enzyme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR007308(Protein of unknown function DUF408)|interpro:IPR038534|interpro:IPR039693|mint:Q8IXW5|rcsb pdb:7B7U|reactome:R-HSA-6807505|ensembl:ENSG00000122484(gene)|ensembl:ENST00000610020(transcript)|go:"GO:0005634"(nucleus)|dip:DIP-32939N refseq:NP_056018.2|ensembl:ENSG00000163125(gene)|ensembl:ENST00000369068(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q5VT52|rcsb pdb:4FLB|reactome:R-HSA-6807505|refseq:NP_001284602.1|refseq:NP_001284603.1|dip:DIP-31155N - - comment:"author score: 89" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:niEFEvqkASycxkzfe9TYJuerUuY9606 rogid:HbkwBBEJ+MNQOjJ2nezU7MJMHYQ9606 rigid:4Es/eEJhQjCnFla54muNKErTv7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXW5 uniprotkb:P24928 intact:EBI-395878|uniprotkb:Q49AS7|uniprotkb:Q9H8Y2|ensembl:ENSP00000476948|uniprotkb:C9JKB5 intact:EBI-295301|uniprotkb:A6NN93|uniprotkb:B9EH88|uniprotkb:Q6NX41|intact:EBI-17957133|intact:EBI-14758660|intact:EBI-13324911|intact:EBI-23311874 psi-mi:rpap2_human(display_long)|uniprotkb:RPAP2(gene name)|psi-mi:RPAP2(display_short)|uniprotkb:C1orf82(gene name synonym)|uniprotkb:RNA polymerase II-associated protein 2(gene name synonym) psi-mi:rpb1_human(display_long)|uniprotkb:POLR2A(gene name)|psi-mi:POLR2A(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit A(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:POLR2(gene name synonym)|uniprotkb:RNA-directed RNA polymerase II subunit RPB1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484015|imex:IM-26985-575 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079089.2|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008420"(RNA polymerase II CTD heptapeptide repeat phosphatase activity)|go:"GO:0009301"(snRNA transcription)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0043175"(RNA polymerase core enzyme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR007308(Protein of unknown function DUF408)|interpro:IPR038534|interpro:IPR039693|mint:Q8IXW5|rcsb pdb:7B7U|reactome:R-HSA-6807505|ensembl:ENSG00000122484(gene)|ensembl:ENST00000610020(transcript)|go:"GO:0005634"(nucleus)|dip:DIP-32939N refseq:NP_000928.1|mint:P24928|dip:DIP-29011N|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0019900"(kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:2GHQ|rcsb pdb:2GHT|rcsb pdb:2LTO|rcsb pdb:3D9K|rcsb pdb:3D9L|rcsb pdb:3D9M|rcsb pdb:3D9N|rcsb pdb:3D9O|rcsb pdb:3D9P|rcsb pdb:4JXT|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:5M3H|rcsb pdb:5M3J|rcsb pdb:6DRD|rcsb pdb:6F5P|rcsb pdb:6G0R|rcsb pdb:6IC8|rcsb pdb:6IC9|rcsb pdb:6O9L|rcsb pdb:6Q5Y|rcsb pdb:6XKB|rcsb pdb:6XRE|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095 - - comment:"author score: 119" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:niEFEvqkASycxkzfe9TYJuerUuY9606 rogid:Si2fgh4AMaNtlzvSQhvsuPusX7s9606 rigid:4Es/eEJhQjCnFla54muNKErTv7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXW5 uniprotkb:P30876 intact:EBI-395878|uniprotkb:Q49AS7|uniprotkb:Q9H8Y2|ensembl:ENSP00000476948|uniprotkb:C9JKB5 intact:EBI-394712|uniprotkb:Q8IZ61|uniprotkb:A8K1A8|ensembl:ENSP00000312735|ensembl:ENSP00000370625 psi-mi:rpap2_human(display_long)|uniprotkb:RPAP2(gene name)|psi-mi:RPAP2(display_short)|uniprotkb:C1orf82(gene name synonym)|uniprotkb:RNA polymerase II-associated protein 2(gene name synonym) psi-mi:rpb2_human(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit B(gene name synonym)|uniprotkb:RNA polymerase II subunit B2(gene name synonym)|uniprotkb:RNA polymerase II subunit 2(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 140 kDa polypeptide(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484015|imex:IM-26985-575 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079089.2|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008420"(RNA polymerase II CTD heptapeptide repeat phosphatase activity)|go:"GO:0009301"(snRNA transcription)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0043175"(RNA polymerase core enzyme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR007308(Protein of unknown function DUF408)|interpro:IPR038534|interpro:IPR039693|mint:Q8IXW5|rcsb pdb:7B7U|reactome:R-HSA-6807505|ensembl:ENSG00000122484(gene)|ensembl:ENST00000610020(transcript)|go:"GO:0005634"(nucleus)|dip:DIP-32939N refseq:NP_000929.1|refseq:NP_001290197.1|refseq:NP_001290198.1|ensembl:ENSG00000047315(gene)|ensembl:ENST00000314595(transcript)|ensembl:ENST00000381227(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|mint:P30876|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32910N - - comment:"author score: 120" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:niEFEvqkASycxkzfe9TYJuerUuY9606 rogid:YhEjtfLk2QnbRPefOp8ZHX0ejak9606 rigid:4Es/eEJhQjCnFla54muNKErTv7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXW5 uniprotkb:P52435 intact:EBI-395878|uniprotkb:Q49AS7|uniprotkb:Q9H8Y2|ensembl:ENSP00000476948|uniprotkb:C9JKB5 intact:EBI-394753|uniprotkb:O43375|uniprotkb:A5D6V8|ensembl:ENSP00000292614 psi-mi:rpap2_human(display_long)|uniprotkb:RPAP2(gene name)|psi-mi:RPAP2(display_short)|uniprotkb:C1orf82(gene name synonym)|uniprotkb:RNA polymerase II-associated protein 2(gene name synonym) psi-mi:rpb11_human(display_long)|uniprotkb:POLR2J(gene name)|psi-mi:POLR2J(display_short)|uniprotkb:POLR2J1(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II subunit J-1(gene name synonym)|uniprotkb:RNA polymerase II 13.3 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484015|imex:IM-26985-575 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079089.2|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008420"(RNA polymerase II CTD heptapeptide repeat phosphatase activity)|go:"GO:0009301"(snRNA transcription)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0043175"(RNA polymerase core enzyme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR007308(Protein of unknown function DUF408)|interpro:IPR038534|interpro:IPR039693|mint:Q8IXW5|rcsb pdb:7B7U|reactome:R-HSA-6807505|ensembl:ENSG00000122484(gene)|ensembl:ENST00000610020(transcript)|go:"GO:0005634"(nucleus)|dip:DIP-32939N refseq:NP_006225.1|ensembl:ENSG00000005075(gene)|ensembl:ENST00000292614(transcript)|go:"GO:0001055"(RNA polymerase II activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0030275"(LRR domain binding)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR008193(DNA-directed RNA polymerase Rpb11, 13-16 kDa subunit, conserved site)|interpro:IPR009025(DNA-directed RNA polymerase, RBP11-like)|interpro:IPR036603|interpro:IPR037685|mint:P52435|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32913N - - comment:"author score: 123" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:niEFEvqkASycxkzfe9TYJuerUuY9606 rogid:jK/DlwFrHHuEJ0Ns3wRoB3icmsA9606 rigid:4Es/eEJhQjCnFla54muNKErTv7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXW5 uniprotkb:P19387 intact:EBI-395878|uniprotkb:Q49AS7|uniprotkb:Q9H8Y2|ensembl:ENSP00000476948|uniprotkb:C9JKB5 intact:EBI-394729|uniprotkb:O15161|ensembl:ENSP00000219252 psi-mi:rpap2_human(display_long)|uniprotkb:RPAP2(gene name)|psi-mi:RPAP2(display_short)|uniprotkb:C1orf82(gene name synonym)|uniprotkb:RNA polymerase II-associated protein 2(gene name synonym) psi-mi:rpb3_human(display_long)|uniprotkb:POLR2C(gene name)|psi-mi:POLR2C(display_short)|uniprotkb:A-152E5.7(orf name)|uniprotkb:DNA-directed RNA polymerase II subunit C(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 33 kDa polypeptide(gene name synonym)|uniprotkb:RPB31(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484015|imex:IM-26985-575 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079089.2|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008420"(RNA polymerase II CTD heptapeptide repeat phosphatase activity)|go:"GO:0009301"(snRNA transcription)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0043175"(RNA polymerase core enzyme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR007308(Protein of unknown function DUF408)|interpro:IPR038534|interpro:IPR039693|mint:Q8IXW5|rcsb pdb:7B7U|reactome:R-HSA-6807505|ensembl:ENSG00000122484(gene)|ensembl:ENST00000610020(transcript)|go:"GO:0005634"(nucleus)|dip:DIP-32939N refseq:NP_116558.1|ensembl:ENSG00000102978(gene)|ensembl:ENST00000219252(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001514(DNA-directed RNA polymerase, 30-40 kDa subunit, conserved site)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR036603|interpro:IPR036643|mint:P19387|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32911N - - comment:"author score: 125" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:niEFEvqkASycxkzfe9TYJuerUuY9606 rogid:UXFC+i+QqB2WRgL9OiYSQ66L36c9606 rigid:4Es/eEJhQjCnFla54muNKErTv7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXW5 uniprotkb:P52434 intact:EBI-395878|uniprotkb:Q49AS7|uniprotkb:Q9H8Y2|ensembl:ENSP00000476948|uniprotkb:C9JKB5 intact:EBI-359505|uniprotkb:P53802|uniprotkb:Q969R0|ensembl:ENSP00000392913|uniprotkb:C9J413|uniprotkb:C9JBJ6|uniprotkb:C9JCU7|uniprotkb:C9JUA8 psi-mi:rpap2_human(display_long)|uniprotkb:RPAP2(gene name)|psi-mi:RPAP2(display_short)|uniprotkb:C1orf82(gene name synonym)|uniprotkb:RNA polymerase II-associated protein 2(gene name synonym) psi-mi:rpab3_human(display_long)|uniprotkb:POLR2H(gene name)|psi-mi:POLR2H(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit H(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I, II, and III 17.1 kDa polypeptide(gene name synonym)|uniprotkb:RPB17(gene name synonym)|uniprotkb:RPB8 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484015|imex:IM-26985-575 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079089.2|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008420"(RNA polymerase II CTD heptapeptide repeat phosphatase activity)|go:"GO:0009301"(snRNA transcription)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0043175"(RNA polymerase core enzyme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR007308(Protein of unknown function DUF408)|interpro:IPR038534|interpro:IPR039693|mint:Q8IXW5|rcsb pdb:7B7U|reactome:R-HSA-6807505|ensembl:ENSG00000122484(gene)|ensembl:ENST00000610020(transcript)|go:"GO:0005634"(nucleus)|dip:DIP-32939N ensembl:ENSG00000163882(gene)|ensembl:ENST00000456318(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032993"(protein-DNA complex)|interpro:IPR005570(RNA polymerase, Rpb8)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:P52434|rcsb pdb:2F3I|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|refseq:NP_006223.2|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|rcsb pdb:7AE3|reactome:R-HSA-1834949|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-427413|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-203927|refseq:NP_001265627.1|refseq:NP_001265628.1|refseq:NP_001265629.1|refseq:NP_001265644.1|refseq:NP_001265643.1|refseq:XP_006713729.1|refseq:XP_006713730.1|refseq:XP_016862125.1|refseq:XP_016862126.1|dip:DIP-27556N - - comment:"author score: 126" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:niEFEvqkASycxkzfe9TYJuerUuY9606 rogid:h7BRWDi8wRbnw/FcFo25bnlVNkE9606 rigid:4Es/eEJhQjCnFla54muNKErTv7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXW5 uniprotkb:P62487 intact:EBI-395878|uniprotkb:Q49AS7|uniprotkb:Q9H8Y2|ensembl:ENSP00000476948|uniprotkb:C9JKB5 intact:EBI-347928|ensembl:ENSP00000301788|uniprotkb:P52433|uniprotkb:Q2M1Z4|uniprotkb:B2R5C0 psi-mi:rpap2_human(display_long)|uniprotkb:RPAP2(gene name)|psi-mi:RPAP2(display_short)|uniprotkb:C1orf82(gene name synonym)|uniprotkb:RNA polymerase II-associated protein 2(gene name synonym) psi-mi:rpb7_human(display_long)|uniprotkb:POLR2G(gene name)|psi-mi:POLR2G(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit G(gene name synonym)|uniprotkb:RPB7(gene name synonym)|uniprotkb:RNA polymerase II 19 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484015|imex:IM-26985-575 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079089.2|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008420"(RNA polymerase II CTD heptapeptide repeat phosphatase activity)|go:"GO:0009301"(snRNA transcription)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0043175"(RNA polymerase core enzyme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR007308(Protein of unknown function DUF408)|interpro:IPR038534|interpro:IPR039693|mint:Q8IXW5|rcsb pdb:7B7U|reactome:R-HSA-6807505|ensembl:ENSG00000122484(gene)|ensembl:ENST00000610020(transcript)|go:"GO:0005634"(nucleus)|dip:DIP-32939N ensembl:ENSG00000168002(gene)|ensembl:ENST00000301788(transcript)|go:"GO:0000291"(nuclear-transcribed mRNA catabolic process, exonucleolytic)|go:"GO:0000932"(P-body)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006915"(apoptotic process)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR003029(S1, RNA binding)|interpro:IPR005576(RNA polymerase Rpb7, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR036898|mint:P62487|rcsb pdb:2C35|rcsb pdb:5IYA|rcsb pdb:5IY6|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|rcsb pdb:5IY7|reactome:R-HSA-167200|reactome:R-HSA-167238|rcsb pdb:5IY8|rcsb pdb:5IY9|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-5601884|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|refseq:NP_002687.1|dip:DIP-32663N - - comment:"author score: 134" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:niEFEvqkASycxkzfe9TYJuerUuY9606 rogid:MtnIweuhSqLFov0c40uOiwv8Eas9606 rigid:4Es/eEJhQjCnFla54muNKErTv7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXW5 uniprotkb:P36954 intact:EBI-395878|uniprotkb:Q49AS7|uniprotkb:Q9H8Y2|ensembl:ENSP00000476948|uniprotkb:C9JKB5 intact:EBI-395202|uniprotkb:Q6NW05|uniprotkb:B2R5J2|ensembl:ENSP00000221859 psi-mi:rpap2_human(display_long)|uniprotkb:RPAP2(gene name)|psi-mi:RPAP2(display_short)|uniprotkb:C1orf82(gene name synonym)|uniprotkb:RNA polymerase II-associated protein 2(gene name synonym) psi-mi:rpb9_human(display_long)|uniprotkb:POLR2I(gene name)|psi-mi:POLR2I(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit I(gene name synonym)|uniprotkb:RNA polymerase II 14.5 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484015|imex:IM-26985-575 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079089.2|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008420"(RNA polymerase II CTD heptapeptide repeat phosphatase activity)|go:"GO:0009301"(snRNA transcription)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0043175"(RNA polymerase core enzyme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR007308(Protein of unknown function DUF408)|interpro:IPR038534|interpro:IPR039693|mint:Q8IXW5|rcsb pdb:7B7U|reactome:R-HSA-6807505|ensembl:ENSG00000122484(gene)|ensembl:ENST00000610020(transcript)|go:"GO:0005634"(nucleus)|dip:DIP-32939N refseq:NP_006224.1|ensembl:ENSG00000105258(gene)|ensembl:ENST00000221859(transcript)|go:"GO:0001193"(maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034012|mint:P36954|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32917N - - comment:"author score: 137" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:niEFEvqkASycxkzfe9TYJuerUuY9606 rogid:YZUW2UDzj1RhCC46iaX1LvYayNA9606 rigid:4Es/eEJhQjCnFla54muNKErTv7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IXW5 uniprotkb:P0CAP2 intact:EBI-395878|uniprotkb:Q49AS7|uniprotkb:Q9H8Y2|ensembl:ENSP00000476948|uniprotkb:C9JKB5 intact:EBI-9657655|uniprotkb:Q96NF5|uniprotkb:Q6EFN8|uniprotkb:Q6EEV3|uniprotkb:Q9Y3V6|uniprotkb:Q8NC58|uniprotkb:Q96DI5|uniprotkb:Q6EF02|uniprotkb:Q6K050|uniprotkb:Q6K046|uniprotkb:Q6K051|uniprotkb:Q6EF01|uniprotkb:Q6EES2|uniprotkb:Q8NCF3|uniprotkb:Q6EM48|uniprotkb:Q6EF46|uniprotkb:Q6ZQZ3|uniprotkb:Q6EER8|uniprotkb:Q96JB7|uniprotkb:Q6EF00|ensembl:ENSP00000299638 psi-mi:rpap2_human(display_long)|uniprotkb:RPAP2(gene name)|psi-mi:RPAP2(display_short)|uniprotkb:C1orf82(gene name synonym)|uniprotkb:RNA polymerase II-associated protein 2(gene name synonym) psi-mi:grl1a_human(display_long)|uniprotkb:POLR2M(gene name)|psi-mi:POLR2M(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit M(gene name synonym)|uniprotkb:GRINL1A(gene name synonym)|uniprotkb:Glutamate receptor-like protein 1A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484015|imex:IM-26985-575 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079089.2|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008420"(RNA polymerase II CTD heptapeptide repeat phosphatase activity)|go:"GO:0009301"(snRNA transcription)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0043175"(RNA polymerase core enzyme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR007308(Protein of unknown function DUF408)|interpro:IPR038534|interpro:IPR039693|mint:Q8IXW5|rcsb pdb:7B7U|reactome:R-HSA-6807505|ensembl:ENSG00000122484(gene)|ensembl:ENST00000610020(transcript)|go:"GO:0005634"(nucleus)|dip:DIP-32939N refseq:NP_001018112.1|refseq:NP_056347.1|dip:DIP-61933N|ensembl:ENSG00000255529(gene)|ensembl:ENST00000299638(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051685"(maintenance of ER location)|interpro:IPR026213|mint:P0CAP2|rcsb pdb:6DRD - - comment:"author score: 168" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:niEFEvqkASycxkzfe9TYJuerUuY9606 rogid:G0QVxeD0uvJTl0VPn+b3pV6zLe89606 rigid:4Es/eEJhQjCnFla54muNKErTv7s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96P16 uniprotkb:Q7KZ85 intact:EBI-1053506|uniprotkb:Q7Z5G8|uniprotkb:Q96FY9|uniprotkb:Q9NVL4|uniprotkb:A8KA42|uniprotkb:B2RBA3|ensembl:ENSP00000349955|ensembl:ENSP00000381984 intact:EBI-2515547|ensembl:ENSP00000319104|ensembl:ENSP00000338143|uniprotkb:Q96AH3|uniprotkb:Q7KYW9|uniprotkb:Q6GMQ4|uniprotkb:Q8N526|uniprotkb:Q15737|uniprotkb:Q9BTI2|uniprotkb:Q92775|uniprotkb:Q9BTH9|uniprotkb:Q7LDK4|uniprotkb:A7E2B4 psi-mi:rpr1a_human(display_long)|uniprotkb:RPRD1A(gene name)|psi-mi:RPRD1A(display_short)|uniprotkb:p15INK4B-related protein(gene name synonym)|uniprotkb:P15RS(gene name synonym)|uniprotkb:Cyclin-dependent kinase inhibitor 2B-related protein(gene name synonym) psi-mi:spt6h_human(display_long)|uniprotkb:SUPT6H(gene name)|psi-mi:SUPT6H(display_short)|uniprotkb:KIAA0162(gene name synonym)|uniprotkb:SPT6H(gene name synonym)|uniprotkb:Tat-cotransactivator 2 protein(gene name synonym)|uniprotkb:Histone chaperone suppressor of Ty6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484063|imex:IM-26985-349 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524350.1|refseq:XP_011524351.1|refseq:XP_011524352.1|refseq:NP_060640.2|refseq:NP_001290340.1|refseq:NP_001290341.1|refseq:NP_001290342.1|ensembl:ENSG00000141425(gene)|ensembl:ENST00000357384(transcript)|ensembl:ENST00000399022(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q96P16|rcsb pdb:4JXT|rcsb pdb:4NAC|reactome:R-HSA-6807505|dip:DIP-50901N go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006397"(mRNA processing)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008380"(RNA splicing)|go:"GO:0010793"(regulation of mRNA export from nucleus)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034728"(nucleosome organization)|go:"GO:0035327"|go:"GO:0042393"(histone binding)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0045191"(regulation of isotype switching)|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0051028"(mRNA transport)|go:"GO:0051147"(regulation of muscle cell differentiation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0070827"(obsolete chromatin maintenance)|interpro:IPR000980(SH2 motif)|interpro:IPR003029(S1, RNA binding)|interpro:IPR006641(Resolvase, RNase H-like fold)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR017072(Transcription elongation factor Spt6)|interpro:IPR022967|interpro:IPR023319|interpro:IPR028083|interpro:IPR028088|interpro:IPR028231|interpro:IPR032706|interpro:IPR035018|interpro:IPR035019|interpro:IPR035420|interpro:IPR036860|interpro:IPR037027|interpro:IPR041692|interpro:IPR042066|mint:Q7KZ85|rcsb pdb:6GME|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|interpro:IPR023323|ensembl:ENSG00000109111(gene)|ensembl:ENST00000314616(transcript)|ensembl:ENST00000347486(transcript)|go:"GO:0001825"(blastocyst formation)|refseq:XP_016880467.1|refseq:XP_016880468.1|refseq:XP_016880469.1|refseq:NP_003161.2|refseq:NP_001307684.1|dip:DIP-42615N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RGCJx8nL9gil6DmtiiFboxeNUSU9606 rogid:G1HKe2xEnti5tcZvbH4uqLOwKNg9606 rigid:D3h92td3FaQ4pUhY/roo1e6xETU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96P16 uniprotkb:Q9H7N4 intact:EBI-1053506|uniprotkb:Q7Z5G8|uniprotkb:Q96FY9|uniprotkb:Q9NVL4|uniprotkb:A8KA42|uniprotkb:B2RBA3|ensembl:ENSP00000349955|ensembl:ENSP00000381984 intact:EBI-1222181|uniprotkb:Q7Z5V7|uniprotkb:Q8WVA1|uniprotkb:Q9NR59|ensembl:ENSP00000353769 psi-mi:rpr1a_human(display_long)|uniprotkb:RPRD1A(gene name)|psi-mi:RPRD1A(display_short)|uniprotkb:p15INK4B-related protein(gene name synonym)|uniprotkb:P15RS(gene name synonym)|uniprotkb:Cyclin-dependent kinase inhibitor 2B-related protein(gene name synonym) psi-mi:sfr19_human(display_long)|uniprotkb:SCAF1(gene name)|psi-mi:SCAF1(display_short)|uniprotkb:SRA1(gene name synonym)|uniprotkb:SFRS19(gene name synonym)|uniprotkb:Serine arginine-rich pre-mRNA splicing factor SR-A1(gene name synonym)|uniprotkb:SR-related-CTD-associated factor(gene name synonym)|uniprotkb:SR-related C-terminal domain-associated factor 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484063|imex:IM-26985-349 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524350.1|refseq:XP_011524351.1|refseq:XP_011524352.1|refseq:NP_060640.2|refseq:NP_001290340.1|refseq:NP_001290341.1|refseq:NP_001290342.1|ensembl:ENSG00000141425(gene)|ensembl:ENST00000357384(transcript)|ensembl:ENST00000399022(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q96P16|rcsb pdb:4JXT|rcsb pdb:4NAC|reactome:R-HSA-6807505|dip:DIP-50901N refseq:NP_067051.2|refseq:XP_005259179.1|ensembl:ENSG00000126461(gene)|ensembl:ENST00000360565(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|interpro:IPR042841|mint:Q9H7N4 - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RGCJx8nL9gil6DmtiiFboxeNUSU9606 rogid:pF10w7xZFQgiVOiZ/mmPKKArwHE9606 rigid:D3h92td3FaQ4pUhY/roo1e6xETU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96P16 uniprotkb:O94762 intact:EBI-1053506|uniprotkb:Q7Z5G8|uniprotkb:Q96FY9|uniprotkb:Q9NVL4|uniprotkb:A8KA42|uniprotkb:B2RBA3|ensembl:ENSP00000349955|ensembl:ENSP00000381984 intact:EBI-395321|ensembl:ENSP00000317636|uniprotkb:Q9P1W7|uniprotkb:Q9UNC8|uniprotkb:Q9H0B1|uniprotkb:Q6P4G0 psi-mi:rpr1a_human(display_long)|uniprotkb:RPRD1A(gene name)|psi-mi:RPRD1A(display_short)|uniprotkb:p15INK4B-related protein(gene name synonym)|uniprotkb:P15RS(gene name synonym)|uniprotkb:Cyclin-dependent kinase inhibitor 2B-related protein(gene name synonym) psi-mi:recq5_human(display_long)|uniprotkb:RECQ5(gene name synonym)|uniprotkb:RECQL5(gene name)|psi-mi:RECQL5(display_short)|uniprotkb:RecQ protein-like 5(gene name synonym)|uniprotkb:DNA helicase, RecQ-like type 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484063|imex:IM-26985-349 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524350.1|refseq:XP_011524351.1|refseq:XP_011524352.1|refseq:NP_060640.2|refseq:NP_001290340.1|refseq:NP_001290341.1|refseq:NP_001290342.1|ensembl:ENSG00000141425(gene)|ensembl:ENST00000357384(transcript)|ensembl:ENST00000399022(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q96P16|rcsb pdb:4JXT|rcsb pdb:4NAC|reactome:R-HSA-6807505|dip:DIP-50901N ensembl:ENSG00000108469(gene)|ensembl:ENST00000317905(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006260"(DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0051301"(cell division)|go:"GO:0051304"(chromosome separation)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR010716(RecQ helicase-like 5)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR032284|interpro:IPR001650(DNA/RNA helicase, C-terminal)|refseq:NP_001003715.1|refseq:NP_001003716.1|refseq:NP_004250.4|mint:O94762|rcsb pdb:4BK0|rcsb pdb:5LB3|rcsb pdb:5LB5|rcsb pdb:5LB8|rcsb pdb:5LBA|refseq:XP_016880832.1|refseq:XP_016880833.1|dip:DIP-32964N - - comment:"author score: 63" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RGCJx8nL9gil6DmtiiFboxeNUSU9606 rogid:lOMr1rIrRi78aQO2pQod/1V3Ku49606 rigid:D3h92td3FaQ4pUhY/roo1e6xETU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96P16 uniprotkb:P53803 intact:EBI-1053506|uniprotkb:Q7Z5G8|uniprotkb:Q96FY9|uniprotkb:Q9NVL4|uniprotkb:A8KA42|uniprotkb:B2RBA3|ensembl:ENSP00000349955|ensembl:ENSP00000381984 intact:EBI-395357|uniprotkb:Q6IBD4|ensembl:ENSP00000342889 psi-mi:rpr1a_human(display_long)|uniprotkb:RPRD1A(gene name)|psi-mi:RPRD1A(display_short)|uniprotkb:p15INK4B-related protein(gene name synonym)|uniprotkb:P15RS(gene name synonym)|uniprotkb:Cyclin-dependent kinase inhibitor 2B-related protein(gene name synonym) psi-mi:rpab4_human(display_long)|uniprotkb:POLR2K(gene name)|psi-mi:POLR2K(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit K(gene name synonym)|uniprotkb:RPB10alpha(gene name synonym)|uniprotkb:RNA polymerase II 7.0 kDa subunit(gene name synonym)|uniprotkb:ABC10-alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484063|imex:IM-26985-349 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524350.1|refseq:XP_011524351.1|refseq:XP_011524352.1|refseq:NP_060640.2|refseq:NP_001290340.1|refseq:NP_001290341.1|refseq:NP_001290342.1|ensembl:ENSG00000141425(gene)|ensembl:ENST00000357384(transcript)|ensembl:ENST00000399022(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q96P16|rcsb pdb:4JXT|rcsb pdb:4NAC|reactome:R-HSA-6807505|dip:DIP-50901N refseq:NP_005025.1|ensembl:ENSG00000147669(gene)|ensembl:ENST00000353107(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006356"(regulation of transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0008270"(zinc ion binding)|interpro:IPR006591(RNA polymerase Rbp10)|interpro:IPR029040|interpro:IPR039747|mint:P53803|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|reactome:R-HSA-203927|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-72086|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32968N - - comment:"author score: 82" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RGCJx8nL9gil6DmtiiFboxeNUSU9606 rogid:dVF/14F1klTHtGh1gfpkGB3YMoU9606 rigid:D3h92td3FaQ4pUhY/roo1e6xETU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96P16 uniprotkb:Q5VT52 intact:EBI-1053506|uniprotkb:Q7Z5G8|uniprotkb:Q96FY9|uniprotkb:Q9NVL4|uniprotkb:A8KA42|uniprotkb:B2RBA3|ensembl:ENSP00000349955|ensembl:ENSP00000381984 intact:EBI-372367|uniprotkb:O75048|uniprotkb:Q5VT53|uniprotkb:Q6MZL4|uniprotkb:Q86XD2|uniprotkb:A8K6N8|uniprotkb:B3KPT1|uniprotkb:Q5VT51|uniprotkb:Q9P0D7|uniprotkb:B4E2Q6|ensembl:ENSP00000358064 psi-mi:rpr1a_human(display_long)|uniprotkb:RPRD1A(gene name)|psi-mi:RPRD1A(display_short)|uniprotkb:p15INK4B-related protein(gene name synonym)|uniprotkb:P15RS(gene name synonym)|uniprotkb:Cyclin-dependent kinase inhibitor 2B-related protein(gene name synonym) psi-mi:rprd2_human(display_long)|uniprotkb:RPRD2(gene name)|psi-mi:RPRD2(display_short)|uniprotkb:KIAA0460(gene name synonym)|uniprotkb:HSPC099(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484063|imex:IM-26985-349 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524350.1|refseq:XP_011524351.1|refseq:XP_011524352.1|refseq:NP_060640.2|refseq:NP_001290340.1|refseq:NP_001290341.1|refseq:NP_001290342.1|ensembl:ENSG00000141425(gene)|ensembl:ENST00000357384(transcript)|ensembl:ENST00000399022(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q96P16|rcsb pdb:4JXT|rcsb pdb:4NAC|reactome:R-HSA-6807505|dip:DIP-50901N refseq:NP_056018.2|ensembl:ENSG00000163125(gene)|ensembl:ENST00000369068(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q5VT52|rcsb pdb:4FLB|reactome:R-HSA-6807505|refseq:NP_001284602.1|refseq:NP_001284603.1|dip:DIP-31155N - - comment:"author score: 105" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RGCJx8nL9gil6DmtiiFboxeNUSU9606 rogid:HbkwBBEJ+MNQOjJ2nezU7MJMHYQ9606 rigid:D3h92td3FaQ4pUhY/roo1e6xETU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96P16 uniprotkb:Q8IXW5 intact:EBI-1053506|uniprotkb:Q7Z5G8|uniprotkb:Q96FY9|uniprotkb:Q9NVL4|uniprotkb:A8KA42|uniprotkb:B2RBA3|ensembl:ENSP00000349955|ensembl:ENSP00000381984 intact:EBI-395878|uniprotkb:Q49AS7|uniprotkb:Q9H8Y2|ensembl:ENSP00000476948|uniprotkb:C9JKB5 psi-mi:rpr1a_human(display_long)|uniprotkb:RPRD1A(gene name)|psi-mi:RPRD1A(display_short)|uniprotkb:p15INK4B-related protein(gene name synonym)|uniprotkb:P15RS(gene name synonym)|uniprotkb:Cyclin-dependent kinase inhibitor 2B-related protein(gene name synonym) psi-mi:rpap2_human(display_long)|uniprotkb:RPAP2(gene name)|psi-mi:RPAP2(display_short)|uniprotkb:C1orf82(gene name synonym)|uniprotkb:RNA polymerase II-associated protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484063|imex:IM-26985-349 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524350.1|refseq:XP_011524351.1|refseq:XP_011524352.1|refseq:NP_060640.2|refseq:NP_001290340.1|refseq:NP_001290341.1|refseq:NP_001290342.1|ensembl:ENSG00000141425(gene)|ensembl:ENST00000357384(transcript)|ensembl:ENST00000399022(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q96P16|rcsb pdb:4JXT|rcsb pdb:4NAC|reactome:R-HSA-6807505|dip:DIP-50901N refseq:NP_079089.2|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008420"(RNA polymerase II CTD heptapeptide repeat phosphatase activity)|go:"GO:0009301"(snRNA transcription)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0043175"(RNA polymerase core enzyme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR007308(Protein of unknown function DUF408)|interpro:IPR038534|interpro:IPR039693|mint:Q8IXW5|rcsb pdb:7B7U|reactome:R-HSA-6807505|ensembl:ENSG00000122484(gene)|ensembl:ENST00000610020(transcript)|go:"GO:0005634"(nucleus)|dip:DIP-32939N - - comment:"author score: 107" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RGCJx8nL9gil6DmtiiFboxeNUSU9606 rogid:niEFEvqkASycxkzfe9TYJuerUuY9606 rigid:D3h92td3FaQ4pUhY/roo1e6xETU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96P16 uniprotkb:P0CAP2 intact:EBI-1053506|uniprotkb:Q7Z5G8|uniprotkb:Q96FY9|uniprotkb:Q9NVL4|uniprotkb:A8KA42|uniprotkb:B2RBA3|ensembl:ENSP00000349955|ensembl:ENSP00000381984 intact:EBI-9657655|uniprotkb:Q96NF5|uniprotkb:Q6EFN8|uniprotkb:Q6EEV3|uniprotkb:Q9Y3V6|uniprotkb:Q8NC58|uniprotkb:Q96DI5|uniprotkb:Q6EF02|uniprotkb:Q6K050|uniprotkb:Q6K046|uniprotkb:Q6K051|uniprotkb:Q6EF01|uniprotkb:Q6EES2|uniprotkb:Q8NCF3|uniprotkb:Q6EM48|uniprotkb:Q6EF46|uniprotkb:Q6ZQZ3|uniprotkb:Q6EER8|uniprotkb:Q96JB7|uniprotkb:Q6EF00|ensembl:ENSP00000299638 psi-mi:rpr1a_human(display_long)|uniprotkb:RPRD1A(gene name)|psi-mi:RPRD1A(display_short)|uniprotkb:p15INK4B-related protein(gene name synonym)|uniprotkb:P15RS(gene name synonym)|uniprotkb:Cyclin-dependent kinase inhibitor 2B-related protein(gene name synonym) psi-mi:grl1a_human(display_long)|uniprotkb:POLR2M(gene name)|psi-mi:POLR2M(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit M(gene name synonym)|uniprotkb:GRINL1A(gene name synonym)|uniprotkb:Glutamate receptor-like protein 1A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484063|imex:IM-26985-349 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524350.1|refseq:XP_011524351.1|refseq:XP_011524352.1|refseq:NP_060640.2|refseq:NP_001290340.1|refseq:NP_001290341.1|refseq:NP_001290342.1|ensembl:ENSG00000141425(gene)|ensembl:ENST00000357384(transcript)|ensembl:ENST00000399022(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q96P16|rcsb pdb:4JXT|rcsb pdb:4NAC|reactome:R-HSA-6807505|dip:DIP-50901N refseq:NP_001018112.1|refseq:NP_056347.1|dip:DIP-61933N|ensembl:ENSG00000255529(gene)|ensembl:ENST00000299638(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051685"(maintenance of ER location)|interpro:IPR026213|mint:P0CAP2|rcsb pdb:6DRD - - comment:"author score: 140" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RGCJx8nL9gil6DmtiiFboxeNUSU9606 rogid:G0QVxeD0uvJTl0VPn+b3pV6zLe89606 rigid:D3h92td3FaQ4pUhY/roo1e6xETU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96P16 uniprotkb:P30876 intact:EBI-1053506|uniprotkb:Q7Z5G8|uniprotkb:Q96FY9|uniprotkb:Q9NVL4|uniprotkb:A8KA42|uniprotkb:B2RBA3|ensembl:ENSP00000349955|ensembl:ENSP00000381984 intact:EBI-394712|uniprotkb:Q8IZ61|uniprotkb:A8K1A8|ensembl:ENSP00000312735|ensembl:ENSP00000370625 psi-mi:rpr1a_human(display_long)|uniprotkb:RPRD1A(gene name)|psi-mi:RPRD1A(display_short)|uniprotkb:p15INK4B-related protein(gene name synonym)|uniprotkb:P15RS(gene name synonym)|uniprotkb:Cyclin-dependent kinase inhibitor 2B-related protein(gene name synonym) psi-mi:rpb2_human(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit B(gene name synonym)|uniprotkb:RNA polymerase II subunit B2(gene name synonym)|uniprotkb:RNA polymerase II subunit 2(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 140 kDa polypeptide(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484063|imex:IM-26985-349 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524350.1|refseq:XP_011524351.1|refseq:XP_011524352.1|refseq:NP_060640.2|refseq:NP_001290340.1|refseq:NP_001290341.1|refseq:NP_001290342.1|ensembl:ENSG00000141425(gene)|ensembl:ENST00000357384(transcript)|ensembl:ENST00000399022(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q96P16|rcsb pdb:4JXT|rcsb pdb:4NAC|reactome:R-HSA-6807505|dip:DIP-50901N refseq:NP_000929.1|refseq:NP_001290197.1|refseq:NP_001290198.1|ensembl:ENSG00000047315(gene)|ensembl:ENST00000314595(transcript)|ensembl:ENST00000381227(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|mint:P30876|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32910N - - comment:"author score: 166" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RGCJx8nL9gil6DmtiiFboxeNUSU9606 rogid:YhEjtfLk2QnbRPefOp8ZHX0ejak9606 rigid:D3h92td3FaQ4pUhY/roo1e6xETU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96P16 uniprotkb:P24928 intact:EBI-1053506|uniprotkb:Q7Z5G8|uniprotkb:Q96FY9|uniprotkb:Q9NVL4|uniprotkb:A8KA42|uniprotkb:B2RBA3|ensembl:ENSP00000349955|ensembl:ENSP00000381984 intact:EBI-295301|uniprotkb:A6NN93|uniprotkb:B9EH88|uniprotkb:Q6NX41|intact:EBI-17957133|intact:EBI-14758660|intact:EBI-13324911|intact:EBI-23311874 psi-mi:rpr1a_human(display_long)|uniprotkb:RPRD1A(gene name)|psi-mi:RPRD1A(display_short)|uniprotkb:p15INK4B-related protein(gene name synonym)|uniprotkb:P15RS(gene name synonym)|uniprotkb:Cyclin-dependent kinase inhibitor 2B-related protein(gene name synonym) psi-mi:rpb1_human(display_long)|uniprotkb:POLR2A(gene name)|psi-mi:POLR2A(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit A(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:POLR2(gene name synonym)|uniprotkb:RNA-directed RNA polymerase II subunit RPB1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484063|imex:IM-26985-349 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524350.1|refseq:XP_011524351.1|refseq:XP_011524352.1|refseq:NP_060640.2|refseq:NP_001290340.1|refseq:NP_001290341.1|refseq:NP_001290342.1|ensembl:ENSG00000141425(gene)|ensembl:ENST00000357384(transcript)|ensembl:ENST00000399022(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q96P16|rcsb pdb:4JXT|rcsb pdb:4NAC|reactome:R-HSA-6807505|dip:DIP-50901N refseq:NP_000928.1|mint:P24928|dip:DIP-29011N|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0019900"(kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:2GHQ|rcsb pdb:2GHT|rcsb pdb:2LTO|rcsb pdb:3D9K|rcsb pdb:3D9L|rcsb pdb:3D9M|rcsb pdb:3D9N|rcsb pdb:3D9O|rcsb pdb:3D9P|rcsb pdb:4JXT|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:5M3H|rcsb pdb:5M3J|rcsb pdb:6DRD|rcsb pdb:6F5P|rcsb pdb:6G0R|rcsb pdb:6IC8|rcsb pdb:6IC9|rcsb pdb:6O9L|rcsb pdb:6Q5Y|rcsb pdb:6XKB|rcsb pdb:6XRE|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095 - - comment:"author score: 173" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RGCJx8nL9gil6DmtiiFboxeNUSU9606 rogid:Si2fgh4AMaNtlzvSQhvsuPusX7s9606 rigid:D3h92td3FaQ4pUhY/roo1e6xETU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96P16 uniprotkb:P62875 intact:EBI-1053506|uniprotkb:Q7Z5G8|uniprotkb:Q96FY9|uniprotkb:Q9NVL4|uniprotkb:A8KA42|uniprotkb:B2RBA3|ensembl:ENSP00000349955|ensembl:ENSP00000381984 intact:EBI-359527|ensembl:ENSP00000324124|ensembl:ENSP00000432807|uniprotkb:P52436|uniprotkb:Q6FHX3 psi-mi:rpr1a_human(display_long)|uniprotkb:RPRD1A(gene name)|psi-mi:RPRD1A(display_short)|uniprotkb:p15INK4B-related protein(gene name synonym)|uniprotkb:P15RS(gene name synonym)|uniprotkb:Cyclin-dependent kinase inhibitor 2B-related protein(gene name synonym) psi-mi:rpab5_human(display_long)|uniprotkb:POLR2L(gene name)|psi-mi:POLR2L(display_short)|uniprotkb:DNA-directed RNA polymerase III subunit L(gene name synonym)|uniprotkb:RPB10 homolog(gene name synonym)|uniprotkb:RNA polymerase II 7.6 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484063|imex:IM-26985-349 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524350.1|refseq:XP_011524351.1|refseq:XP_011524352.1|refseq:NP_060640.2|refseq:NP_001290340.1|refseq:NP_001290341.1|refseq:NP_001290342.1|ensembl:ENSG00000141425(gene)|ensembl:ENST00000357384(transcript)|ensembl:ENST00000399022(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q96P16|rcsb pdb:4JXT|rcsb pdb:4NAC|reactome:R-HSA-6807505|dip:DIP-50901N ensembl:ENSG00000177700(gene)|ensembl:ENST00000322028(transcript)|ensembl:ENST00000534030(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006356"(regulation of transcription by RNA polymerase I)|go:"GO:0006360"(transcription by RNA polymerase I)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042797"(tRNA transcription by RNA polymerase III)|interpro:IPR000268(RNA polymerases, N/8 Kd subunits)|interpro:IPR020789|interpro:IPR023580|mint:P62875|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-1834949|refseq:NP_066951.1|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-75955|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-203927|dip:DIP-32960N - - comment:"author score: 177" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RGCJx8nL9gil6DmtiiFboxeNUSU9606 rogid:uDzgKgHzFTPxFaV1GeUYdYMa4Gk9606 rigid:D3h92td3FaQ4pUhY/roo1e6xETU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96P16 uniprotkb:P36954 intact:EBI-1053506|uniprotkb:Q7Z5G8|uniprotkb:Q96FY9|uniprotkb:Q9NVL4|uniprotkb:A8KA42|uniprotkb:B2RBA3|ensembl:ENSP00000349955|ensembl:ENSP00000381984 intact:EBI-395202|uniprotkb:Q6NW05|uniprotkb:B2R5J2|ensembl:ENSP00000221859 psi-mi:rpr1a_human(display_long)|uniprotkb:RPRD1A(gene name)|psi-mi:RPRD1A(display_short)|uniprotkb:p15INK4B-related protein(gene name synonym)|uniprotkb:P15RS(gene name synonym)|uniprotkb:Cyclin-dependent kinase inhibitor 2B-related protein(gene name synonym) psi-mi:rpb9_human(display_long)|uniprotkb:POLR2I(gene name)|psi-mi:POLR2I(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit I(gene name synonym)|uniprotkb:RNA polymerase II 14.5 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484063|imex:IM-26985-349 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524350.1|refseq:XP_011524351.1|refseq:XP_011524352.1|refseq:NP_060640.2|refseq:NP_001290340.1|refseq:NP_001290341.1|refseq:NP_001290342.1|ensembl:ENSG00000141425(gene)|ensembl:ENST00000357384(transcript)|ensembl:ENST00000399022(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q96P16|rcsb pdb:4JXT|rcsb pdb:4NAC|reactome:R-HSA-6807505|dip:DIP-50901N refseq:NP_006224.1|ensembl:ENSG00000105258(gene)|ensembl:ENST00000221859(transcript)|go:"GO:0001193"(maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034012|mint:P36954|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32917N - - comment:"author score: 189" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RGCJx8nL9gil6DmtiiFboxeNUSU9606 rogid:YZUW2UDzj1RhCC46iaX1LvYayNA9606 rigid:D3h92td3FaQ4pUhY/roo1e6xETU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96P16 uniprotkb:P19387 intact:EBI-1053506|uniprotkb:Q7Z5G8|uniprotkb:Q96FY9|uniprotkb:Q9NVL4|uniprotkb:A8KA42|uniprotkb:B2RBA3|ensembl:ENSP00000349955|ensembl:ENSP00000381984 intact:EBI-394729|uniprotkb:O15161|ensembl:ENSP00000219252 psi-mi:rpr1a_human(display_long)|uniprotkb:RPRD1A(gene name)|psi-mi:RPRD1A(display_short)|uniprotkb:p15INK4B-related protein(gene name synonym)|uniprotkb:P15RS(gene name synonym)|uniprotkb:Cyclin-dependent kinase inhibitor 2B-related protein(gene name synonym) psi-mi:rpb3_human(display_long)|uniprotkb:POLR2C(gene name)|psi-mi:POLR2C(display_short)|uniprotkb:A-152E5.7(orf name)|uniprotkb:DNA-directed RNA polymerase II subunit C(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 33 kDa polypeptide(gene name synonym)|uniprotkb:RPB31(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484063|imex:IM-26985-349 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524350.1|refseq:XP_011524351.1|refseq:XP_011524352.1|refseq:NP_060640.2|refseq:NP_001290340.1|refseq:NP_001290341.1|refseq:NP_001290342.1|ensembl:ENSG00000141425(gene)|ensembl:ENST00000357384(transcript)|ensembl:ENST00000399022(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q96P16|rcsb pdb:4JXT|rcsb pdb:4NAC|reactome:R-HSA-6807505|dip:DIP-50901N refseq:NP_116558.1|ensembl:ENSG00000102978(gene)|ensembl:ENST00000219252(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001514(DNA-directed RNA polymerase, 30-40 kDa subunit, conserved site)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR036603|interpro:IPR036643|mint:P19387|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32911N - - comment:"author score: 192" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RGCJx8nL9gil6DmtiiFboxeNUSU9606 rogid:UXFC+i+QqB2WRgL9OiYSQ66L36c9606 rigid:D3h92td3FaQ4pUhY/roo1e6xETU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96P16 uniprotkb:P52434 intact:EBI-1053506|uniprotkb:Q7Z5G8|uniprotkb:Q96FY9|uniprotkb:Q9NVL4|uniprotkb:A8KA42|uniprotkb:B2RBA3|ensembl:ENSP00000349955|ensembl:ENSP00000381984 intact:EBI-359505|uniprotkb:P53802|uniprotkb:Q969R0|ensembl:ENSP00000392913|uniprotkb:C9J413|uniprotkb:C9JBJ6|uniprotkb:C9JCU7|uniprotkb:C9JUA8 psi-mi:rpr1a_human(display_long)|uniprotkb:RPRD1A(gene name)|psi-mi:RPRD1A(display_short)|uniprotkb:p15INK4B-related protein(gene name synonym)|uniprotkb:P15RS(gene name synonym)|uniprotkb:Cyclin-dependent kinase inhibitor 2B-related protein(gene name synonym) psi-mi:rpab3_human(display_long)|uniprotkb:POLR2H(gene name)|psi-mi:POLR2H(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit H(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I, II, and III 17.1 kDa polypeptide(gene name synonym)|uniprotkb:RPB17(gene name synonym)|uniprotkb:RPB8 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484063|imex:IM-26985-349 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524350.1|refseq:XP_011524351.1|refseq:XP_011524352.1|refseq:NP_060640.2|refseq:NP_001290340.1|refseq:NP_001290341.1|refseq:NP_001290342.1|ensembl:ENSG00000141425(gene)|ensembl:ENST00000357384(transcript)|ensembl:ENST00000399022(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q96P16|rcsb pdb:4JXT|rcsb pdb:4NAC|reactome:R-HSA-6807505|dip:DIP-50901N ensembl:ENSG00000163882(gene)|ensembl:ENST00000456318(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032993"(protein-DNA complex)|interpro:IPR005570(RNA polymerase, Rpb8)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:P52434|rcsb pdb:2F3I|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|refseq:NP_006223.2|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|rcsb pdb:7AE3|reactome:R-HSA-1834949|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-427413|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-203927|refseq:NP_001265627.1|refseq:NP_001265628.1|refseq:NP_001265629.1|refseq:NP_001265644.1|refseq:NP_001265643.1|refseq:XP_006713729.1|refseq:XP_006713730.1|refseq:XP_016862125.1|refseq:XP_016862126.1|dip:DIP-27556N - - comment:"author score: 200" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RGCJx8nL9gil6DmtiiFboxeNUSU9606 rogid:h7BRWDi8wRbnw/FcFo25bnlVNkE9606 rigid:D3h92td3FaQ4pUhY/roo1e6xETU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96P16 uniprotkb:P62487 intact:EBI-1053506|uniprotkb:Q7Z5G8|uniprotkb:Q96FY9|uniprotkb:Q9NVL4|uniprotkb:A8KA42|uniprotkb:B2RBA3|ensembl:ENSP00000349955|ensembl:ENSP00000381984 intact:EBI-347928|ensembl:ENSP00000301788|uniprotkb:P52433|uniprotkb:Q2M1Z4|uniprotkb:B2R5C0 psi-mi:rpr1a_human(display_long)|uniprotkb:RPRD1A(gene name)|psi-mi:RPRD1A(display_short)|uniprotkb:p15INK4B-related protein(gene name synonym)|uniprotkb:P15RS(gene name synonym)|uniprotkb:Cyclin-dependent kinase inhibitor 2B-related protein(gene name synonym) psi-mi:rpb7_human(display_long)|uniprotkb:POLR2G(gene name)|psi-mi:POLR2G(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit G(gene name synonym)|uniprotkb:RPB7(gene name synonym)|uniprotkb:RNA polymerase II 19 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484063|imex:IM-26985-349 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524350.1|refseq:XP_011524351.1|refseq:XP_011524352.1|refseq:NP_060640.2|refseq:NP_001290340.1|refseq:NP_001290341.1|refseq:NP_001290342.1|ensembl:ENSG00000141425(gene)|ensembl:ENST00000357384(transcript)|ensembl:ENST00000399022(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q96P16|rcsb pdb:4JXT|rcsb pdb:4NAC|reactome:R-HSA-6807505|dip:DIP-50901N ensembl:ENSG00000168002(gene)|ensembl:ENST00000301788(transcript)|go:"GO:0000291"(nuclear-transcribed mRNA catabolic process, exonucleolytic)|go:"GO:0000932"(P-body)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006915"(apoptotic process)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR003029(S1, RNA binding)|interpro:IPR005576(RNA polymerase Rpb7, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR036898|mint:P62487|rcsb pdb:2C35|rcsb pdb:5IYA|rcsb pdb:5IY6|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|rcsb pdb:5IY7|reactome:R-HSA-167200|reactome:R-HSA-167238|rcsb pdb:5IY8|rcsb pdb:5IY9|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-5601884|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|refseq:NP_002687.1|dip:DIP-32663N - - comment:"author score: 208" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RGCJx8nL9gil6DmtiiFboxeNUSU9606 rogid:MtnIweuhSqLFov0c40uOiwv8Eas9606 rigid:D3h92td3FaQ4pUhY/roo1e6xETU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96P16 uniprotkb:P52435 intact:EBI-1053506|uniprotkb:Q7Z5G8|uniprotkb:Q96FY9|uniprotkb:Q9NVL4|uniprotkb:A8KA42|uniprotkb:B2RBA3|ensembl:ENSP00000349955|ensembl:ENSP00000381984 intact:EBI-394753|uniprotkb:O43375|uniprotkb:A5D6V8|ensembl:ENSP00000292614 psi-mi:rpr1a_human(display_long)|uniprotkb:RPRD1A(gene name)|psi-mi:RPRD1A(display_short)|uniprotkb:p15INK4B-related protein(gene name synonym)|uniprotkb:P15RS(gene name synonym)|uniprotkb:Cyclin-dependent kinase inhibitor 2B-related protein(gene name synonym) psi-mi:rpb11_human(display_long)|uniprotkb:POLR2J(gene name)|psi-mi:POLR2J(display_short)|uniprotkb:POLR2J1(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II subunit J-1(gene name synonym)|uniprotkb:RNA polymerase II 13.3 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484063|imex:IM-26985-349 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011524350.1|refseq:XP_011524351.1|refseq:XP_011524352.1|refseq:NP_060640.2|refseq:NP_001290340.1|refseq:NP_001290341.1|refseq:NP_001290342.1|ensembl:ENSG00000141425(gene)|ensembl:ENST00000357384(transcript)|ensembl:ENST00000399022(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q96P16|rcsb pdb:4JXT|rcsb pdb:4NAC|reactome:R-HSA-6807505|dip:DIP-50901N refseq:NP_006225.1|ensembl:ENSG00000005075(gene)|ensembl:ENST00000292614(transcript)|go:"GO:0001055"(RNA polymerase II activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0030275"(LRR domain binding)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR008193(DNA-directed RNA polymerase Rpb11, 13-16 kDa subunit, conserved site)|interpro:IPR009025(DNA-directed RNA polymerase, RBP11-like)|interpro:IPR036603|interpro:IPR037685|mint:P52435|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32913N - - comment:"author score: 219" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:RGCJx8nL9gil6DmtiiFboxeNUSU9606 rogid:jK/DlwFrHHuEJ0Ns3wRoB3icmsA9606 rigid:D3h92td3FaQ4pUhY/roo1e6xETU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQG5 uniprotkb:Q8NFD5 intact:EBI-747925|uniprotkb:Q1WDE7|uniprotkb:Q6PKF4|ensembl:ENSP00000362532 intact:EBI-679921|uniprotkb:Q5JRD1|uniprotkb:Q5VYC4|uniprotkb:Q8IZY8|uniprotkb:Q8TEV0|uniprotkb:Q8TF02|uniprotkb:Q99491|uniprotkb:Q9ULI5|intact:EBI-2560572|ensembl:ENSP00000055163 psi-mi:rpr1b_human(display_long)|uniprotkb:RPRD1B(gene name)|psi-mi:RPRD1B(display_short)|uniprotkb:C20orf77(gene name synonym)|uniprotkb:CREPT(gene name synonym)|uniprotkb:Cell cycle-related and expression-elevated protein in tumor(gene name synonym) psi-mi:ari1b_human(display_long)|uniprotkb:BAF250B(gene name synonym)|uniprotkb:Osa homolog 2(gene name synonym)|uniprotkb:p250R(gene name synonym)|uniprotkb:BRG1-binding protein hELD/OSA1(gene name synonym)|uniprotkb:BRG1-associated factor 250b(gene name synonym)|uniprotkb:ARID1B(gene name)|psi-mi:ARID1B(display_short)|uniprotkb:DAN15(gene name synonym)|uniprotkb:KIAA1235(gene name synonym)|uniprotkb:OSA2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484114|imex:IM-26985-273 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067038.1|ensembl:ENSG00000101413(gene)|ensembl:ENST00000373433(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q9NQG5|rcsb pdb:4FLA|rcsb pdb:4FU3|rcsb pdb:4HFG|rcsb pdb:4NAD|rcsb pdb:4Q94|rcsb pdb:4Q96|reactome:R-HSA-6807505|dip:DIP-61537N refseq:NP_001333742.1|refseq:NP_059989.2|refseq:NP_065783.3|ensembl:ENSG00000049618(gene)|ensembl:ENST00000350026(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0035060"(brahma complex)|go:"GO:0043044"|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048096"|go:"GO:0071565"(nBAF complex)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR021906|interpro:IPR033388|interpro:IPR036431|interpro:IPR038040|mint:Q8NFD5|rcsb pdb:2CXY|rcsb pdb:2EH9|reactome:R-HSA-3214858|reactome:R-HSA-8939243 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:1P0sOiLV5eQXrRj+vENpc6L/z/Q9606 rogid:BeWhuwPk5f6HN+yasFEJRpkbM6A9606 rigid:FsFrNKThHbuUiXLcs6E7wVPM+7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQG5 uniprotkb:Q9H7N4 intact:EBI-747925|uniprotkb:Q1WDE7|uniprotkb:Q6PKF4|ensembl:ENSP00000362532 intact:EBI-1222181|uniprotkb:Q7Z5V7|uniprotkb:Q8WVA1|uniprotkb:Q9NR59|ensembl:ENSP00000353769 psi-mi:rpr1b_human(display_long)|uniprotkb:RPRD1B(gene name)|psi-mi:RPRD1B(display_short)|uniprotkb:C20orf77(gene name synonym)|uniprotkb:CREPT(gene name synonym)|uniprotkb:Cell cycle-related and expression-elevated protein in tumor(gene name synonym) psi-mi:sfr19_human(display_long)|uniprotkb:SCAF1(gene name)|psi-mi:SCAF1(display_short)|uniprotkb:SRA1(gene name synonym)|uniprotkb:SFRS19(gene name synonym)|uniprotkb:Serine arginine-rich pre-mRNA splicing factor SR-A1(gene name synonym)|uniprotkb:SR-related-CTD-associated factor(gene name synonym)|uniprotkb:SR-related C-terminal domain-associated factor 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484114|imex:IM-26985-273 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067038.1|ensembl:ENSG00000101413(gene)|ensembl:ENST00000373433(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q9NQG5|rcsb pdb:4FLA|rcsb pdb:4FU3|rcsb pdb:4HFG|rcsb pdb:4NAD|rcsb pdb:4Q94|rcsb pdb:4Q96|reactome:R-HSA-6807505|dip:DIP-61537N refseq:NP_067051.2|refseq:XP_005259179.1|ensembl:ENSG00000126461(gene)|ensembl:ENST00000360565(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0099122"(RNA polymerase II C-terminal domain binding)|interpro:IPR042841|mint:Q9H7N4 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:1P0sOiLV5eQXrRj+vENpc6L/z/Q9606 rogid:pF10w7xZFQgiVOiZ/mmPKKArwHE9606 rigid:FsFrNKThHbuUiXLcs6E7wVPM+7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQG5 uniprotkb:P08758 intact:EBI-747925|uniprotkb:Q1WDE7|uniprotkb:Q6PKF4|ensembl:ENSP00000362532 intact:EBI-296601|ensembl:ENSP00000296511|uniprotkb:Q6FI16|uniprotkb:Q8WV69|uniprotkb:Q6FHB3|uniprotkb:Q9UDH9|uniprotkb:D3DNW7 psi-mi:rpr1b_human(display_long)|uniprotkb:RPRD1B(gene name)|psi-mi:RPRD1B(display_short)|uniprotkb:C20orf77(gene name synonym)|uniprotkb:CREPT(gene name synonym)|uniprotkb:Cell cycle-related and expression-elevated protein in tumor(gene name synonym) psi-mi:anxa5_human(display_long)|uniprotkb:ANXA5(gene name)|psi-mi:ANXA5(display_short)|uniprotkb:ANX5(gene name synonym)|uniprotkb:ENX2(gene name synonym)|uniprotkb:PP4(gene name synonym)|uniprotkb:Annexin-5(gene name synonym)|uniprotkb:Annexin V(gene name synonym)|uniprotkb:Lipocortin V(gene name synonym)|uniprotkb:Endonexin II(gene name synonym)|uniprotkb:Calphobindin I(gene name synonym)|uniprotkb:Placental anticoagulant protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein 4(gene name synonym)|uniprotkb:Thromboplastin inhibitor(gene name synonym)|uniprotkb:Vascular anticoagulant-alpha(gene name synonym)|uniprotkb:Anchorin CII(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484114|imex:IM-26985-273 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067038.1|ensembl:ENSG00000101413(gene)|ensembl:ENST00000373433(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q9NQG5|rcsb pdb:4FLA|rcsb pdb:4FU3|rcsb pdb:4HFG|rcsb pdb:4NAD|rcsb pdb:4Q94|rcsb pdb:4Q96|reactome:R-HSA-6807505|dip:DIP-61537N ensembl:ENSG00000164111(gene)|ensembl:ENST00000296511(transcript)|go:"GO:0004859"(phospholipase inhibitor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007596"(blood coagulation)|go:"GO:0016020"(membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050819"(negative regulation of coagulation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001464(Annexin)|interpro:IPR002392(Annexin, type V)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P08758|rcsb pdb:1ANW|rcsb pdb:1ANX|rcsb pdb:1AVH|rcsb pdb:1AVR|rcsb pdb:1HAK|rcsb pdb:1HVD|rcsb pdb:1HVE|rcsb pdb:1HVF|rcsb pdb:1HVG|rcsb pdb:1SAV|rcsb pdb:2XO2|rcsb pdb:2XO3|rcsb pdb:6K22|rcsb pdb:6K25|reactome:R-HSA-114608|refseq:NP_001145.1 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:1P0sOiLV5eQXrRj+vENpc6L/z/Q9606 rogid:vIp2wWkAz7uOtQSzbUJick5bT5o9606 rigid:FsFrNKThHbuUiXLcs6E7wVPM+7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQG5 uniprotkb:O94762 intact:EBI-747925|uniprotkb:Q1WDE7|uniprotkb:Q6PKF4|ensembl:ENSP00000362532 intact:EBI-395321|ensembl:ENSP00000317636|uniprotkb:Q9P1W7|uniprotkb:Q9UNC8|uniprotkb:Q9H0B1|uniprotkb:Q6P4G0 psi-mi:rpr1b_human(display_long)|uniprotkb:RPRD1B(gene name)|psi-mi:RPRD1B(display_short)|uniprotkb:C20orf77(gene name synonym)|uniprotkb:CREPT(gene name synonym)|uniprotkb:Cell cycle-related and expression-elevated protein in tumor(gene name synonym) psi-mi:recq5_human(display_long)|uniprotkb:RECQ5(gene name synonym)|uniprotkb:RECQL5(gene name)|psi-mi:RECQL5(display_short)|uniprotkb:RecQ protein-like 5(gene name synonym)|uniprotkb:DNA helicase, RecQ-like type 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484114|imex:IM-26985-273 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067038.1|ensembl:ENSG00000101413(gene)|ensembl:ENST00000373433(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q9NQG5|rcsb pdb:4FLA|rcsb pdb:4FU3|rcsb pdb:4HFG|rcsb pdb:4NAD|rcsb pdb:4Q94|rcsb pdb:4Q96|reactome:R-HSA-6807505|dip:DIP-61537N ensembl:ENSG00000108469(gene)|ensembl:ENST00000317905(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006260"(DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0009378"(four-way junction helicase activity)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035690"|go:"GO:0042802"(identical protein binding)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0051301"(cell division)|go:"GO:0051304"(chromosome separation)|go:"GO:0072757"(cellular response to camptothecin)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR004589(DNA helicase, ATP-dependent, RecQ type)|interpro:IPR010716(RecQ helicase-like 5)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR032284|interpro:IPR001650(DNA/RNA helicase, C-terminal)|refseq:NP_001003715.1|refseq:NP_001003716.1|refseq:NP_004250.4|mint:O94762|rcsb pdb:4BK0|rcsb pdb:5LB3|rcsb pdb:5LB5|rcsb pdb:5LB8|rcsb pdb:5LBA|refseq:XP_016880832.1|refseq:XP_016880833.1|dip:DIP-32964N - - comment:"author score: 38" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:1P0sOiLV5eQXrRj+vENpc6L/z/Q9606 rogid:lOMr1rIrRi78aQO2pQod/1V3Ku49606 rigid:FsFrNKThHbuUiXLcs6E7wVPM+7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQG5 uniprotkb:Q8IXW5 intact:EBI-747925|uniprotkb:Q1WDE7|uniprotkb:Q6PKF4|ensembl:ENSP00000362532 intact:EBI-395878|uniprotkb:Q49AS7|uniprotkb:Q9H8Y2|ensembl:ENSP00000476948|uniprotkb:C9JKB5 psi-mi:rpr1b_human(display_long)|uniprotkb:RPRD1B(gene name)|psi-mi:RPRD1B(display_short)|uniprotkb:C20orf77(gene name synonym)|uniprotkb:CREPT(gene name synonym)|uniprotkb:Cell cycle-related and expression-elevated protein in tumor(gene name synonym) psi-mi:rpap2_human(display_long)|uniprotkb:RPAP2(gene name)|psi-mi:RPAP2(display_short)|uniprotkb:C1orf82(gene name synonym)|uniprotkb:RNA polymerase II-associated protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484114|imex:IM-26985-273 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067038.1|ensembl:ENSG00000101413(gene)|ensembl:ENST00000373433(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q9NQG5|rcsb pdb:4FLA|rcsb pdb:4FU3|rcsb pdb:4HFG|rcsb pdb:4NAD|rcsb pdb:4Q94|rcsb pdb:4Q96|reactome:R-HSA-6807505|dip:DIP-61537N refseq:NP_079089.2|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008420"(RNA polymerase II CTD heptapeptide repeat phosphatase activity)|go:"GO:0009301"(snRNA transcription)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0043175"(RNA polymerase core enzyme binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR007308(Protein of unknown function DUF408)|interpro:IPR038534|interpro:IPR039693|mint:Q8IXW5|rcsb pdb:7B7U|reactome:R-HSA-6807505|ensembl:ENSG00000122484(gene)|ensembl:ENST00000610020(transcript)|go:"GO:0005634"(nucleus)|dip:DIP-32939N - - comment:"author score: 84" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:1P0sOiLV5eQXrRj+vENpc6L/z/Q9606 rogid:niEFEvqkASycxkzfe9TYJuerUuY9606 rigid:FsFrNKThHbuUiXLcs6E7wVPM+7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQG5 uniprotkb:Q5VT52 intact:EBI-747925|uniprotkb:Q1WDE7|uniprotkb:Q6PKF4|ensembl:ENSP00000362532 intact:EBI-372367|uniprotkb:O75048|uniprotkb:Q5VT53|uniprotkb:Q6MZL4|uniprotkb:Q86XD2|uniprotkb:A8K6N8|uniprotkb:B3KPT1|uniprotkb:Q5VT51|uniprotkb:Q9P0D7|uniprotkb:B4E2Q6|ensembl:ENSP00000358064 psi-mi:rpr1b_human(display_long)|uniprotkb:RPRD1B(gene name)|psi-mi:RPRD1B(display_short)|uniprotkb:C20orf77(gene name synonym)|uniprotkb:CREPT(gene name synonym)|uniprotkb:Cell cycle-related and expression-elevated protein in tumor(gene name synonym) psi-mi:rprd2_human(display_long)|uniprotkb:RPRD2(gene name)|psi-mi:RPRD2(display_short)|uniprotkb:KIAA0460(gene name synonym)|uniprotkb:HSPC099(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484114|imex:IM-26985-273 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067038.1|ensembl:ENSG00000101413(gene)|ensembl:ENST00000373433(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q9NQG5|rcsb pdb:4FLA|rcsb pdb:4FU3|rcsb pdb:4HFG|rcsb pdb:4NAD|rcsb pdb:4Q94|rcsb pdb:4Q96|reactome:R-HSA-6807505|dip:DIP-61537N refseq:NP_056018.2|ensembl:ENSG00000163125(gene)|ensembl:ENST00000369068(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q5VT52|rcsb pdb:4FLB|reactome:R-HSA-6807505|refseq:NP_001284602.1|refseq:NP_001284603.1|dip:DIP-31155N - - comment:"author score: 102" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:1P0sOiLV5eQXrRj+vENpc6L/z/Q9606 rogid:HbkwBBEJ+MNQOjJ2nezU7MJMHYQ9606 rigid:FsFrNKThHbuUiXLcs6E7wVPM+7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQG5 uniprotkb:P0CAP2 intact:EBI-747925|uniprotkb:Q1WDE7|uniprotkb:Q6PKF4|ensembl:ENSP00000362532 intact:EBI-9657655|uniprotkb:Q96NF5|uniprotkb:Q6EFN8|uniprotkb:Q6EEV3|uniprotkb:Q9Y3V6|uniprotkb:Q8NC58|uniprotkb:Q96DI5|uniprotkb:Q6EF02|uniprotkb:Q6K050|uniprotkb:Q6K046|uniprotkb:Q6K051|uniprotkb:Q6EF01|uniprotkb:Q6EES2|uniprotkb:Q8NCF3|uniprotkb:Q6EM48|uniprotkb:Q6EF46|uniprotkb:Q6ZQZ3|uniprotkb:Q6EER8|uniprotkb:Q96JB7|uniprotkb:Q6EF00|ensembl:ENSP00000299638 psi-mi:rpr1b_human(display_long)|uniprotkb:RPRD1B(gene name)|psi-mi:RPRD1B(display_short)|uniprotkb:C20orf77(gene name synonym)|uniprotkb:CREPT(gene name synonym)|uniprotkb:Cell cycle-related and expression-elevated protein in tumor(gene name synonym) psi-mi:grl1a_human(display_long)|uniprotkb:POLR2M(gene name)|psi-mi:POLR2M(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit M(gene name synonym)|uniprotkb:GRINL1A(gene name synonym)|uniprotkb:Glutamate receptor-like protein 1A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484114|imex:IM-26985-273 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067038.1|ensembl:ENSG00000101413(gene)|ensembl:ENST00000373433(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q9NQG5|rcsb pdb:4FLA|rcsb pdb:4FU3|rcsb pdb:4HFG|rcsb pdb:4NAD|rcsb pdb:4Q94|rcsb pdb:4Q96|reactome:R-HSA-6807505|dip:DIP-61537N refseq:NP_001018112.1|refseq:NP_056347.1|dip:DIP-61933N|ensembl:ENSG00000255529(gene)|ensembl:ENST00000299638(transcript)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043025"(neuronal cell body)|go:"GO:0051685"(maintenance of ER location)|interpro:IPR026213|mint:P0CAP2|rcsb pdb:6DRD - - comment:"author score: 115" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:1P0sOiLV5eQXrRj+vENpc6L/z/Q9606 rogid:G0QVxeD0uvJTl0VPn+b3pV6zLe89606 rigid:FsFrNKThHbuUiXLcs6E7wVPM+7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQG5 uniprotkb:P30876 intact:EBI-747925|uniprotkb:Q1WDE7|uniprotkb:Q6PKF4|ensembl:ENSP00000362532 intact:EBI-394712|uniprotkb:Q8IZ61|uniprotkb:A8K1A8|ensembl:ENSP00000312735|ensembl:ENSP00000370625 psi-mi:rpr1b_human(display_long)|uniprotkb:RPRD1B(gene name)|psi-mi:RPRD1B(display_short)|uniprotkb:C20orf77(gene name synonym)|uniprotkb:CREPT(gene name synonym)|uniprotkb:Cell cycle-related and expression-elevated protein in tumor(gene name synonym) psi-mi:rpb2_human(display_long)|uniprotkb:POLR2B(gene name)|psi-mi:POLR2B(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit B(gene name synonym)|uniprotkb:RNA polymerase II subunit B2(gene name synonym)|uniprotkb:RNA polymerase II subunit 2(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 140 kDa polypeptide(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484114|imex:IM-26985-273 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067038.1|ensembl:ENSG00000101413(gene)|ensembl:ENST00000373433(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q9NQG5|rcsb pdb:4FLA|rcsb pdb:4FU3|rcsb pdb:4HFG|rcsb pdb:4NAD|rcsb pdb:4Q94|rcsb pdb:4Q96|reactome:R-HSA-6807505|dip:DIP-61537N refseq:NP_000929.1|refseq:NP_001290197.1|refseq:NP_001290198.1|ensembl:ENSG00000047315(gene)|ensembl:ENST00000314595(transcript)|ensembl:ENST00000381227(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0032549"(ribonucleoside binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR007120(DNA-directed RNA polymerase, subunit 2, domain 6)|interpro:IPR007121(RNA polymerase, beta subunit, conserved site)|interpro:IPR007641(RNA polymerase Rpb2, domain 7)|interpro:IPR007642(RNA polymerase Rpb2, domain 2)|interpro:IPR007644(RNA polymerase, beta subunit, protrusion)|interpro:IPR007645(RNA polymerase Rpb2, domain 3)|interpro:IPR007646(RNA polymerase Rpb2, domain 4)|interpro:IPR007647(RNA polymerase Rpb2, domain 5)|interpro:IPR014724(RNA polymerase Rpb2, OB-fold)|interpro:IPR015712(DNA-directed RNA polymerase, subunit 2)|interpro:IPR037033|interpro:IPR037034|mint:P30876|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32910N - - comment:"author score: 156" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:1P0sOiLV5eQXrRj+vENpc6L/z/Q9606 rogid:YhEjtfLk2QnbRPefOp8ZHX0ejak9606 rigid:FsFrNKThHbuUiXLcs6E7wVPM+7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQG5 uniprotkb:P24928 intact:EBI-747925|uniprotkb:Q1WDE7|uniprotkb:Q6PKF4|ensembl:ENSP00000362532 intact:EBI-295301|uniprotkb:A6NN93|uniprotkb:B9EH88|uniprotkb:Q6NX41|intact:EBI-17957133|intact:EBI-14758660|intact:EBI-13324911|intact:EBI-23311874 psi-mi:rpr1b_human(display_long)|uniprotkb:RPRD1B(gene name)|psi-mi:RPRD1B(display_short)|uniprotkb:C20orf77(gene name synonym)|uniprotkb:CREPT(gene name synonym)|uniprotkb:Cell cycle-related and expression-elevated protein in tumor(gene name synonym) psi-mi:rpb1_human(display_long)|uniprotkb:POLR2A(gene name)|psi-mi:POLR2A(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit A(gene name synonym)|uniprotkb:DNA-directed RNA polymerase III largest subunit(gene name synonym)|uniprotkb:POLR2(gene name synonym)|uniprotkb:RNA-directed RNA polymerase II subunit RPB1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484114|imex:IM-26985-273 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067038.1|ensembl:ENSG00000101413(gene)|ensembl:ENST00000373433(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q9NQG5|rcsb pdb:4FLA|rcsb pdb:4FU3|rcsb pdb:4HFG|rcsb pdb:4NAD|rcsb pdb:4Q94|rcsb pdb:4Q96|reactome:R-HSA-6807505|dip:DIP-61537N refseq:NP_000928.1|mint:P24928|dip:DIP-29011N|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0003968"(RNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0019900"(kinase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR000722(RNA polymerase, alpha subunit)|interpro:IPR006592(RNA polymerase, N-terminal)|interpro:IPR007066(RNA polymerase Rpb1, domain 3)|interpro:IPR007073(RNA polymerase Rpb1, domain 7)|interpro:IPR007075(RNA polymerase Rpb1, domain 6)|interpro:IPR007080(RNA polymerase Rpb1, domain 1)|interpro:IPR007081(RNA polymerase Rpb1, domain 5)|interpro:IPR007083(RNA polymerase Rpb1, domain 4)|interpro:IPR038120|interpro:IPR038593|interpro:IPR042102|rcsb pdb:2GHQ|rcsb pdb:2GHT|rcsb pdb:2LTO|rcsb pdb:3D9K|rcsb pdb:3D9L|rcsb pdb:3D9M|rcsb pdb:3D9N|rcsb pdb:3D9O|rcsb pdb:3D9P|rcsb pdb:4JXT|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:5M3H|rcsb pdb:5M3J|rcsb pdb:6DRD|rcsb pdb:6F5P|rcsb pdb:6G0R|rcsb pdb:6IC8|rcsb pdb:6IC9|rcsb pdb:6O9L|rcsb pdb:6Q5Y|rcsb pdb:6XKB|rcsb pdb:6XRE|rcsb pdb:7EGB|rcsb pdb:7EGC|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095 - - comment:"author score: 158" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:1P0sOiLV5eQXrRj+vENpc6L/z/Q9606 rogid:Si2fgh4AMaNtlzvSQhvsuPusX7s9606 rigid:FsFrNKThHbuUiXLcs6E7wVPM+7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQG5 uniprotkb:P52435 intact:EBI-747925|uniprotkb:Q1WDE7|uniprotkb:Q6PKF4|ensembl:ENSP00000362532 intact:EBI-394753|uniprotkb:O43375|uniprotkb:A5D6V8|ensembl:ENSP00000292614 psi-mi:rpr1b_human(display_long)|uniprotkb:RPRD1B(gene name)|psi-mi:RPRD1B(display_short)|uniprotkb:C20orf77(gene name synonym)|uniprotkb:CREPT(gene name synonym)|uniprotkb:Cell cycle-related and expression-elevated protein in tumor(gene name synonym) psi-mi:rpb11_human(display_long)|uniprotkb:POLR2J(gene name)|psi-mi:POLR2J(display_short)|uniprotkb:POLR2J1(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II subunit J-1(gene name synonym)|uniprotkb:RNA polymerase II 13.3 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484114|imex:IM-26985-273 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067038.1|ensembl:ENSG00000101413(gene)|ensembl:ENST00000373433(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q9NQG5|rcsb pdb:4FLA|rcsb pdb:4FU3|rcsb pdb:4HFG|rcsb pdb:4NAD|rcsb pdb:4Q94|rcsb pdb:4Q96|reactome:R-HSA-6807505|dip:DIP-61537N refseq:NP_006225.1|ensembl:ENSG00000005075(gene)|ensembl:ENST00000292614(transcript)|go:"GO:0001055"(RNA polymerase II activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0030275"(LRR domain binding)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR008193(DNA-directed RNA polymerase Rpb11, 13-16 kDa subunit, conserved site)|interpro:IPR009025(DNA-directed RNA polymerase, RBP11-like)|interpro:IPR036603|interpro:IPR037685|mint:P52435|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32913N - - comment:"author score: 172" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:1P0sOiLV5eQXrRj+vENpc6L/z/Q9606 rogid:jK/DlwFrHHuEJ0Ns3wRoB3icmsA9606 rigid:FsFrNKThHbuUiXLcs6E7wVPM+7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQG5 uniprotkb:P62487 intact:EBI-747925|uniprotkb:Q1WDE7|uniprotkb:Q6PKF4|ensembl:ENSP00000362532 intact:EBI-347928|ensembl:ENSP00000301788|uniprotkb:P52433|uniprotkb:Q2M1Z4|uniprotkb:B2R5C0 psi-mi:rpr1b_human(display_long)|uniprotkb:RPRD1B(gene name)|psi-mi:RPRD1B(display_short)|uniprotkb:C20orf77(gene name synonym)|uniprotkb:CREPT(gene name synonym)|uniprotkb:Cell cycle-related and expression-elevated protein in tumor(gene name synonym) psi-mi:rpb7_human(display_long)|uniprotkb:POLR2G(gene name)|psi-mi:POLR2G(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit G(gene name synonym)|uniprotkb:RPB7(gene name synonym)|uniprotkb:RNA polymerase II 19 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484114|imex:IM-26985-273 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067038.1|ensembl:ENSG00000101413(gene)|ensembl:ENST00000373433(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q9NQG5|rcsb pdb:4FLA|rcsb pdb:4FU3|rcsb pdb:4HFG|rcsb pdb:4NAD|rcsb pdb:4Q94|rcsb pdb:4Q96|reactome:R-HSA-6807505|dip:DIP-61537N ensembl:ENSG00000168002(gene)|ensembl:ENST00000301788(transcript)|go:"GO:0000291"(nuclear-transcribed mRNA catabolic process, exonucleolytic)|go:"GO:0000932"(P-body)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006915"(apoptotic process)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|interpro:IPR003029(S1, RNA binding)|interpro:IPR005576(RNA polymerase Rpb7, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR022967|interpro:IPR036898|mint:P62487|rcsb pdb:2C35|rcsb pdb:5IYA|rcsb pdb:5IY6|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|rcsb pdb:5IY7|reactome:R-HSA-167200|reactome:R-HSA-167238|rcsb pdb:5IY8|rcsb pdb:5IY9|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-5601884|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|refseq:NP_002687.1|dip:DIP-32663N - - comment:"author score: 180" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:1P0sOiLV5eQXrRj+vENpc6L/z/Q9606 rogid:MtnIweuhSqLFov0c40uOiwv8Eas9606 rigid:FsFrNKThHbuUiXLcs6E7wVPM+7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQG5 uniprotkb:P52434 intact:EBI-747925|uniprotkb:Q1WDE7|uniprotkb:Q6PKF4|ensembl:ENSP00000362532 intact:EBI-359505|uniprotkb:P53802|uniprotkb:Q969R0|ensembl:ENSP00000392913|uniprotkb:C9J413|uniprotkb:C9JBJ6|uniprotkb:C9JCU7|uniprotkb:C9JUA8 psi-mi:rpr1b_human(display_long)|uniprotkb:RPRD1B(gene name)|psi-mi:RPRD1B(display_short)|uniprotkb:C20orf77(gene name synonym)|uniprotkb:CREPT(gene name synonym)|uniprotkb:Cell cycle-related and expression-elevated protein in tumor(gene name synonym) psi-mi:rpab3_human(display_long)|uniprotkb:POLR2H(gene name)|psi-mi:POLR2H(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit H(gene name synonym)|uniprotkb:DNA-directed RNA polymerases I, II, and III 17.1 kDa polypeptide(gene name synonym)|uniprotkb:RPB17(gene name synonym)|uniprotkb:RPB8 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484114|imex:IM-26985-273 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067038.1|ensembl:ENSG00000101413(gene)|ensembl:ENST00000373433(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q9NQG5|rcsb pdb:4FLA|rcsb pdb:4FU3|rcsb pdb:4HFG|rcsb pdb:4NAD|rcsb pdb:4Q94|rcsb pdb:4Q96|reactome:R-HSA-6807505|dip:DIP-61537N ensembl:ENSG00000163882(gene)|ensembl:ENST00000456318(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005736"(RNA polymerase I complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0032993"(protein-DNA complex)|interpro:IPR005570(RNA polymerase, Rpb8)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:P52434|rcsb pdb:2F3I|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7A6H|rcsb pdb:7AE1|refseq:NP_006223.2|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|rcsb pdb:7AE3|reactome:R-HSA-1834949|reactome:R-HSA-5250924|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-427413|reactome:R-HSA-72203|reactome:R-HSA-73762|reactome:R-HSA-73772|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-73780|reactome:R-HSA-73863|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|reactome:R-HSA-203927|refseq:NP_001265627.1|refseq:NP_001265628.1|refseq:NP_001265629.1|refseq:NP_001265644.1|refseq:NP_001265643.1|refseq:XP_006713729.1|refseq:XP_006713730.1|refseq:XP_016862125.1|refseq:XP_016862126.1|dip:DIP-27556N - - comment:"author score: 181" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:1P0sOiLV5eQXrRj+vENpc6L/z/Q9606 rogid:h7BRWDi8wRbnw/FcFo25bnlVNkE9606 rigid:FsFrNKThHbuUiXLcs6E7wVPM+7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQG5 uniprotkb:P19387 intact:EBI-747925|uniprotkb:Q1WDE7|uniprotkb:Q6PKF4|ensembl:ENSP00000362532 intact:EBI-394729|uniprotkb:O15161|ensembl:ENSP00000219252 psi-mi:rpr1b_human(display_long)|uniprotkb:RPRD1B(gene name)|psi-mi:RPRD1B(display_short)|uniprotkb:C20orf77(gene name synonym)|uniprotkb:CREPT(gene name synonym)|uniprotkb:Cell cycle-related and expression-elevated protein in tumor(gene name synonym) psi-mi:rpb3_human(display_long)|uniprotkb:POLR2C(gene name)|psi-mi:POLR2C(display_short)|uniprotkb:A-152E5.7(orf name)|uniprotkb:DNA-directed RNA polymerase II subunit C(gene name synonym)|uniprotkb:DNA-directed RNA polymerase II 33 kDa polypeptide(gene name synonym)|uniprotkb:RPB31(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484114|imex:IM-26985-273 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067038.1|ensembl:ENSG00000101413(gene)|ensembl:ENST00000373433(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q9NQG5|rcsb pdb:4FLA|rcsb pdb:4FU3|rcsb pdb:4HFG|rcsb pdb:4NAD|rcsb pdb:4Q94|rcsb pdb:4Q96|reactome:R-HSA-6807505|dip:DIP-61537N refseq:NP_116558.1|ensembl:ENSG00000102978(gene)|ensembl:ENST00000219252(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|interpro:IPR001514(DNA-directed RNA polymerase, 30-40 kDa subunit, conserved site)|interpro:IPR011262(DNA-directed RNA polymerase, insert)|interpro:IPR011263(DNA-directed RNA polymerase, RpoA/D/Rpb3-type)|interpro:IPR036603|interpro:IPR036643|mint:P19387|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32911N - - comment:"author score: 185" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:1P0sOiLV5eQXrRj+vENpc6L/z/Q9606 rogid:UXFC+i+QqB2WRgL9OiYSQ66L36c9606 rigid:FsFrNKThHbuUiXLcs6E7wVPM+7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQG5 uniprotkb:O15514 intact:EBI-747925|uniprotkb:Q1WDE7|uniprotkb:Q6PKF4|ensembl:ENSP00000362532 intact:EBI-394737|uniprotkb:Q52LT4|ensembl:ENSP00000272645 psi-mi:rpr1b_human(display_long)|uniprotkb:RPRD1B(gene name)|psi-mi:RPRD1B(display_short)|uniprotkb:C20orf77(gene name synonym)|uniprotkb:CREPT(gene name synonym)|uniprotkb:Cell cycle-related and expression-elevated protein in tumor(gene name synonym) psi-mi:rpb4_human(display_long)|uniprotkb:POLR2D(gene name)|psi-mi:POLR2D(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit D(gene name synonym)|uniprotkb:RNA polymerase II 16 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484114|imex:IM-26985-273 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067038.1|ensembl:ENSG00000101413(gene)|ensembl:ENST00000373433(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q9NQG5|rcsb pdb:4FLA|rcsb pdb:4FU3|rcsb pdb:4HFG|rcsb pdb:4NAD|rcsb pdb:4Q94|rcsb pdb:4Q96|reactome:R-HSA-6807505|dip:DIP-61537N refseq:NP_004796.1|ensembl:ENSG00000144231(gene)|ensembl:ENST00000272645(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0000288"(nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:0000932"(P-body)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0016607"(nuclear speck)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031990"(mRNA export from nucleus in response to heat stress)|go:"GO:0034402"(recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex)|go:"GO:0045948"(positive regulation of translational initiation)|interpro:IPR005574(RNA polymerase II, Rpb4)|interpro:IPR006590(RNA polymerase II, Rpb4, core)|interpro:IPR010997(HRDC-like)|interpro:IPR038324|mint:O15514|rcsb pdb:2C35|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32912N - - comment:"author score: 185" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:1P0sOiLV5eQXrRj+vENpc6L/z/Q9606 rogid:qOGCRZ4FNc6fSBgoKUgbbCSHm889606 rigid:FsFrNKThHbuUiXLcs6E7wVPM+7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQG5 uniprotkb:P36954 intact:EBI-747925|uniprotkb:Q1WDE7|uniprotkb:Q6PKF4|ensembl:ENSP00000362532 intact:EBI-395202|uniprotkb:Q6NW05|uniprotkb:B2R5J2|ensembl:ENSP00000221859 psi-mi:rpr1b_human(display_long)|uniprotkb:RPRD1B(gene name)|psi-mi:RPRD1B(display_short)|uniprotkb:C20orf77(gene name synonym)|uniprotkb:CREPT(gene name synonym)|uniprotkb:Cell cycle-related and expression-elevated protein in tumor(gene name synonym) psi-mi:rpb9_human(display_long)|uniprotkb:POLR2I(gene name)|psi-mi:POLR2I(display_short)|uniprotkb:DNA-directed RNA polymerase II subunit I(gene name synonym)|uniprotkb:RNA polymerase II 14.5 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484114|imex:IM-26985-273 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067038.1|ensembl:ENSG00000101413(gene)|ensembl:ENST00000373433(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q9NQG5|rcsb pdb:4FLA|rcsb pdb:4FU3|rcsb pdb:4HFG|rcsb pdb:4NAD|rcsb pdb:4Q94|rcsb pdb:4Q96|reactome:R-HSA-6807505|dip:DIP-61537N refseq:NP_006224.1|ensembl:ENSG00000105258(gene)|ensembl:ENST00000221859(transcript)|go:"GO:0001193"(maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005665"(RNA polymerase II, core complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006379"(mRNA cleavage)|go:"GO:0008270"(zinc ion binding)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034012|mint:P36954|rcsb pdb:5IY6|rcsb pdb:5IY7|rcsb pdb:5IY8|rcsb pdb:5IY9|rcsb pdb:5IYA|rcsb pdb:5IYB|rcsb pdb:5IYC|rcsb pdb:5IYD|rcsb pdb:6DRD|rcsb pdb:6O9L|rcsb pdb:6XRE|rcsb pdb:7LBM|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-168325|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-5601884|reactome:R-HSA-5617472|reactome:R-HSA-674695|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6796648|reactome:R-HSA-6803529|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72203|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-75955|reactome:R-HSA-76042|reactome:R-HSA-77075|reactome:R-HSA-8851708|reactome:R-HSA-9018519|reactome:R-HSA-9670095|dip:DIP-32917N - - comment:"author score: 189" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:1P0sOiLV5eQXrRj+vENpc6L/z/Q9606 rogid:YZUW2UDzj1RhCC46iaX1LvYayNA9606 rigid:FsFrNKThHbuUiXLcs6E7wVPM+7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQG5 uniprotkb:Q96P16 intact:EBI-747925|uniprotkb:Q1WDE7|uniprotkb:Q6PKF4|ensembl:ENSP00000362532 intact:EBI-1053506|uniprotkb:Q7Z5G8|uniprotkb:Q96FY9|uniprotkb:Q9NVL4|uniprotkb:A8KA42|uniprotkb:B2RBA3|ensembl:ENSP00000349955|ensembl:ENSP00000381984 psi-mi:rpr1b_human(display_long)|uniprotkb:RPRD1B(gene name)|psi-mi:RPRD1B(display_short)|uniprotkb:C20orf77(gene name synonym)|uniprotkb:CREPT(gene name synonym)|uniprotkb:Cell cycle-related and expression-elevated protein in tumor(gene name synonym) psi-mi:rpr1a_human(display_long)|uniprotkb:RPRD1A(gene name)|psi-mi:RPRD1A(display_short)|uniprotkb:p15INK4B-related protein(gene name synonym)|uniprotkb:P15RS(gene name synonym)|uniprotkb:Cyclin-dependent kinase inhibitor 2B-related protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484114|imex:IM-26985-273 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_067038.1|ensembl:ENSG00000101413(gene)|ensembl:ENST00000373433(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q9NQG5|rcsb pdb:4FLA|rcsb pdb:4FU3|rcsb pdb:4HFG|rcsb pdb:4NAD|rcsb pdb:4Q94|rcsb pdb:4Q96|reactome:R-HSA-6807505|dip:DIP-61537N refseq:XP_011524350.1|refseq:XP_011524351.1|refseq:XP_011524352.1|refseq:NP_060640.2|refseq:NP_001290340.1|refseq:NP_001290341.1|refseq:NP_001290342.1|ensembl:ENSG00000141425(gene)|ensembl:ENST00000357384(transcript)|ensembl:ENST00000399022(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q96P16|rcsb pdb:4JXT|rcsb pdb:4NAC|reactome:R-HSA-6807505|dip:DIP-50901N - - comment:"author score: 356" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:1P0sOiLV5eQXrRj+vENpc6L/z/Q9606 rogid:RGCJx8nL9gil6DmtiiFboxeNUSU9606 rigid:FsFrNKThHbuUiXLcs6E7wVPM+7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ49 uniprotkb:P20719 intact:EBI-2362709|uniprotkb:Q5TD36|uniprotkb:Q6ZS26|uniprotkb:Q8NAG7|uniprotkb:A8K4P3|ensembl:ENSP00000272091 intact:EBI-8470697|uniprotkb:Q96CY6|intact:MINT-2801671|uniprotkb:O43367|uniprotkb:A4D179|ensembl:ENSP00000222726 psi-mi:sde2_human(display_long)|uniprotkb:SDE2(gene name)|psi-mi:SDE2(display_short)|uniprotkb:C1orf55(gene name synonym) psi-mi:hxa5_human(display_long)|uniprotkb:HOXA5(gene name)|psi-mi:HOXA5(display_short)|uniprotkb:HOX1C(gene name synonym)|uniprotkb:Homeobox protein Hox-1C(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484369|imex:IM-26985-55 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_689821.3|ensembl:ENSG00000143751(gene)|ensembl:ENST00000272091(transcript)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0016485"(protein processing)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016607"(nuclear speck)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0034644"(cellular response to UV)|go:"GO:0051301"(cell division)|interpro:IPR024974|mint:Q6IQ49|rcsb pdb:6QDV refseq:NP_061975.2|ensembl:ENSG00000106004(gene)|ensembl:ENST00000222726(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003016"(respiratory system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016477"(cell migration)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030878"(thyroid gland development)|go:"GO:0033599"(regulation of mammary gland epithelial cell proliferation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045639"(positive regulation of myeloid cell differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0060435"(bronchiole development)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060480"(lung goblet cell differentiation)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060535"(trachea cartilage morphogenesis)|go:"GO:0060574"(intestinal epithelial cell maturation)|go:"GO:0060638"(mesenchymal-epithelial cell signaling)|go:"GO:0060644"(mammary gland epithelial cell differentiation)|go:"GO:0060749"(mammary gland alveolus development)|go:"GO:0060764"(cell-cell signaling involved in mammary gland development)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|mint:P20719 - - comment:mint|comment:homomint|function:Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Also binds to its own promoter. Binds specifically to the motif 5'-CYYNATTA[TG]Y-3'|comment:"author score: 52" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ykYmjWUVmJODk3kwvOO7oYwjdao9606 rogid:1W+oOoovKja439tdjkg3QjmSB9Q9606 rigid:lcbS4vzDl30hqI5e04GGA9GQCNs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ49 uniprotkb:P17509 intact:EBI-2362709|uniprotkb:Q5TD36|uniprotkb:Q6ZS26|uniprotkb:Q8NAG7|uniprotkb:A8K4P3|ensembl:ENSP00000272091 intact:EBI-741308|ensembl:ENSP00000225648|ensembl:ENSP00000420009|uniprotkb:P09068|uniprotkb:Q9HB11|uniprotkb:Q9UGH2|uniprotkb:A8K835|uniprotkb:D3DTV5 psi-mi:sde2_human(display_long)|uniprotkb:SDE2(gene name)|psi-mi:SDE2(display_short)|uniprotkb:C1orf55(gene name synonym) psi-mi:hxb6_human(display_long)|uniprotkb:Homeobox protein Hox-2B(gene name synonym)|uniprotkb:Homeobox protein Hox-2.2(gene name synonym)|uniprotkb:Homeobox protein Hu-2(gene name synonym)|uniprotkb:HOXB6(gene name)|psi-mi:HOXB6(display_short)|uniprotkb:HOX2B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484369|imex:IM-26985-55 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_689821.3|ensembl:ENSG00000143751(gene)|ensembl:ENST00000272091(transcript)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0016485"(protein processing)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016607"(nuclear speck)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0034644"(cellular response to UV)|go:"GO:0051301"(cell division)|interpro:IPR024974|mint:Q6IQ49|rcsb pdb:6QDV go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR001356(Homeobox)|interpro:IPR001827(Homeobox protein, antennapedia type)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017970|interpro:IPR017995|interpro:IPR020479|mint:P17509|ensembl:ENSG00000108511(gene)|ensembl:ENST00000225648(transcript)|ensembl:ENST00000484302(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|refseq:NP_061825.2|refseq:XP_005257340.1|refseq:XP_005257341.1 - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ykYmjWUVmJODk3kwvOO7oYwjdao9606 rogid:5MTUEA03jhudRW4zALviuhMFPPc9606 rigid:lcbS4vzDl30hqI5e04GGA9GQCNs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6IQ49 uniprotkb:Q96EW2 intact:EBI-2362709|uniprotkb:Q5TD36|uniprotkb:Q6ZS26|uniprotkb:Q8NAG7|uniprotkb:A8K4P3|ensembl:ENSP00000272091 intact:EBI-720457|uniprotkb:Q6P476|uniprotkb:Q8N8J4|uniprotkb:Q8NHH6|uniprotkb:Q8WWF0|ensembl:ENSP00000302562 psi-mi:sde2_human(display_long)|uniprotkb:SDE2(gene name)|psi-mi:SDE2(display_short)|uniprotkb:C1orf55(gene name synonym) psi-mi:hbap1_human(display_long)|uniprotkb:27 kDa heat shock protein-associated protein 1(gene name synonym)|uniprotkb:Protein associated with small stress protein 1(gene name synonym)|uniprotkb:HSPBAP1(gene name)|psi-mi:HSPBAP1(display_short)|uniprotkb:PASS1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484369|imex:IM-26985-55 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_689821.3|ensembl:ENSG00000143751(gene)|ensembl:ENST00000272091(transcript)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006260"(DNA replication)|go:"GO:0016485"(protein processing)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016607"(nuclear speck)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0034644"(cellular response to UV)|go:"GO:0051301"(cell division)|interpro:IPR024974|mint:Q6IQ49|rcsb pdb:6QDV refseq:NP_078886.2|ensembl:ENSG00000169087(gene)|ensembl:ENST00000306103(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR013296("Protein Associated with Small Stress protein 1 (PASS1)")|interpro:IPR041667|mint:Q96EW2|refseq:NP_001307657.1|refseq:XP_005247819.1 - - comment:"author score: 281" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ykYmjWUVmJODk3kwvOO7oYwjdao9606 rogid:5KvIFh1GwZSyAKD2EloRz2oweNk9606 rigid:lcbS4vzDl30hqI5e04GGA9GQCNs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UQR0 uniprotkb:P35030 intact:EBI-2513111|ensembl:ENSP00000251900|uniprotkb:Q8IWD0|uniprotkb:Q86U98|uniprotkb:Q8NDP2|uniprotkb:Q9UGC5|uniprotkb:Q5JXE6 intact:EBI-1221209|uniprotkb:Q5VXV0|intact:EBI-2825937|uniprotkb:A8CED3|uniprotkb:F8W7P3|uniprotkb:Q6ISJ4|uniprotkb:P15951|uniprotkb:Q15665|uniprotkb:Q9UQV3|uniprotkb:A9Z1Y4|uniprotkb:E7ES07|uniprotkb:A8CED1 psi-mi:scml2_human(display_long)|uniprotkb:SCML2(gene name)|psi-mi:SCML2(display_short) psi-mi:try3_human(display_long)|uniprotkb:PRSS3(gene name)|psi-mi:PRSS3(display_short)|uniprotkb:PRSS4(gene name synonym)|uniprotkb:TRY3(gene name synonym)|uniprotkb:TRY4(gene name synonym)|uniprotkb:Trypsin III(gene name synonym)|uniprotkb:Brain trypsinogen(gene name synonym)|uniprotkb:Mesotrypsinogen(gene name synonym)|uniprotkb:Trypsin IV(gene name synonym)|uniprotkb:Serine protease 3(gene name synonym)|uniprotkb:Serine protease 4(gene name synonym)|uniprotkb:Mesotrypsin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484354|imex:IM-26985-577 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102098(gene)|ensembl:ENST00000251900(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0031519"(PcG protein complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR033763|interpro:IPR038348|mint:Q9UQR0|rcsb pdb:1OI1|rcsb pdb:2BIV|rcsb pdb:2MEM|rcsb pdb:2VYT|rcsb pdb:4EDU|refseq:NP_006080.1|refseq:XP_016884708.1|refseq:XP_016884709.1|dip:DIP-53760N refseq:NP_002762.2|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|refseq:NP_001184026.2|refseq:NP_031369.2|refseq:NP_001184027.1|mint:P35030|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0007586"(digestion)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0031638"(zymogen activation)|go:"GO:0043542"(endothelial cell migration)|go:"GO:1904724"(tertiary granule lumen)|rcsb pdb:1H4W|rcsb pdb:2R9P|rcsb pdb:3L33|rcsb pdb:3L3T|rcsb pdb:3P92|rcsb pdb:3P95|rcsb pdb:4DG4|rcsb pdb:4U30|rcsb pdb:4U32|rcsb pdb:5C67|rcsb pdb:5JBT|rcsb pdb:5TP0|rcsb pdb:6BX8|rcsb pdb:6GFI|reactome:R-HSA-1462054|reactome:R-HSA-196741|reactome:R-HSA-6798695|reactome:R-HSA-6803157|interpro:IPR043504 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:6nmElZ2VXM/O5RZx+i1iu9JnsK09606 rogid:AEfz7orXeNoasizB5N76AkF4WMk9606 rigid:5TSWJAYldLgfkASWEtII6xGuZJ0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UQR0 uniprotkb:P01040 intact:EBI-2513111|ensembl:ENSP00000251900|uniprotkb:Q8IWD0|uniprotkb:Q86U98|uniprotkb:Q8NDP2|uniprotkb:Q9UGC5|uniprotkb:Q5JXE6 intact:EBI-724303|ensembl:ENSP00000264474|uniprotkb:Q6IB90 psi-mi:scml2_human(display_long)|uniprotkb:SCML2(gene name)|psi-mi:SCML2(display_short) psi-mi:cyta_human(display_long)|uniprotkb:Cystatin-AS(gene name synonym)|uniprotkb:Stefin-A(gene name synonym)|uniprotkb:CSTA(gene name)|psi-mi:CSTA(display_short)|uniprotkb:STF1(gene name synonym)|uniprotkb:STFA(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484354|imex:IM-26985-577 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102098(gene)|ensembl:ENST00000251900(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0031519"(PcG protein complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR033763|interpro:IPR038348|mint:Q9UQR0|rcsb pdb:1OI1|rcsb pdb:2BIV|rcsb pdb:2MEM|rcsb pdb:2VYT|rcsb pdb:4EDU|refseq:NP_006080.1|refseq:XP_016884708.1|refseq:XP_016884709.1|dip:DIP-53760N refseq:NP_005204.1|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR001713(Proteinase inhibitor I25A, stefin A)|mint:P01040|rcsb pdb:1CYU|rcsb pdb:1CYV|rcsb pdb:1DVC|rcsb pdb:1DVD|rcsb pdb:1GD3|rcsb pdb:1GD4|rcsb pdb:1N9J|rcsb pdb:1NB3|rcsb pdb:1NB5|rcsb pdb:3K9M|rcsb pdb:3KFQ|interpro:IPR018073|rcsb pdb:3KSE|reactome:R-HSA-6809371|ensembl:ENSG00000121552(gene)|ensembl:ENST00000264474(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002020"(protease binding)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0045861"(negative regulation of proteolysis) - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:6nmElZ2VXM/O5RZx+i1iu9JnsK09606 rogid:SzbpyWUHlOtItIvffzuwhcqFsDI9606 rigid:5TSWJAYldLgfkASWEtII6xGuZJ0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UQR0 uniprotkb:P22528 intact:EBI-2513111|ensembl:ENSP00000251900|uniprotkb:Q8IWD0|uniprotkb:Q86U98|uniprotkb:Q8NDP2|uniprotkb:Q9UGC5|uniprotkb:Q5JXE6 intact:EBI-1058892|ensembl:ENSP00000306461|uniprotkb:B2R5H7|uniprotkb:P22529|uniprotkb:P22530|uniprotkb:Q5T524 psi-mi:scml2_human(display_long)|uniprotkb:SCML2(gene name)|psi-mi:SCML2(display_short) psi-mi:spr1b_human(display_long)|uniprotkb:SPRR1B(gene name)|psi-mi:SPRR1B(display_short)|uniprotkb:Small proline-rich protein IB(gene name synonym)|uniprotkb:14.9 kDa pancornulin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484354|imex:IM-26985-577 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000102098(gene)|ensembl:ENST00000251900(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0031519"(PcG protein complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR033763|interpro:IPR038348|mint:Q9UQR0|rcsb pdb:1OI1|rcsb pdb:2BIV|rcsb pdb:2MEM|rcsb pdb:2VYT|rcsb pdb:4EDU|refseq:NP_006080.1|refseq:XP_016884708.1|refseq:XP_016884709.1|dip:DIP-53760N ensembl:ENSG00000169469(gene)|ensembl:ENST00000307098(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0031424"(keratinization)|interpro:IPR003302("Cornifin (SPRR)")|mint:P22528|reactome:R-HSA-6809371|refseq:NP_003116.2 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:6nmElZ2VXM/O5RZx+i1iu9JnsK09606 rogid:WU0vu+DHdIJm0x40HdcpAdJgdgo9606 rigid:5TSWJAYldLgfkASWEtII6xGuZJ0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96GD3 uniprotkb:P16104 intact:EBI-713793|uniprotkb:Q5VT76|uniprotkb:Q6IAJ4|uniprotkb:Q8WU48|uniprotkb:Q9UKM5|uniprotkb:Q9UKM6|ensembl:ENSP00000318094|ensembl:ENSP00000380359|uniprotkb:B4DRQ8 intact:EBI-494830|uniprotkb:Q4ZGJ7|uniprotkb:Q6IAS5|ensembl:ENSP00000364310|ensembl:ENSP00000434024 psi-mi:scmh1_human(display_long)|uniprotkb:Sex comb on midleg homolog 1(gene name synonym)|uniprotkb:SCMH1(gene name)|psi-mi:SCMH1(display_short) psi-mi:h2ax_human(display_long)|uniprotkb:H2AX(gene name)|psi-mi:H2AX(display_short)|uniprotkb:H2AFX(gene name synonym)|uniprotkb:Histone H2A.X(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484312|imex:IM-26985-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006710527.1|ensembl:ENSG00000010803(gene)|ensembl:ENST00000326197(transcript)|ensembl:ENST00000397174(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010369"(chromocenter)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|go:"GO:0005634"(nucleus)|interpro:IPR021987|interpro:IPR033763|interpro:IPR038348|mint:Q96GD3|rcsb pdb:2P0K|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|refseq:NP_001026864.1|refseq:NP_001165689.1|refseq:NP_001165690.1|refseq:NP_001165691.1|refseq:NP_001165692.1|refseq:NP_001165693.1|refseq:NP_036368.1|refseq:XP_016856188.1|refseq:XP_016856196.1|refseq:XP_011539335.1|refseq:XP_011539338.1 ensembl:ENSG00000188486(gene)|ensembl:ENST00000375167(transcript)|ensembl:ENST00000530167(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000786"(nucleosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|refseq:NP_002096.1|dip:DIP-33604N|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|go:"GO:0005813"(centrosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090398"(cellular senescence)|go:"GO:0090734"(site of DNA damage)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P16104|rcsb pdb:1YDP|rcsb pdb:2AZM|rcsb pdb:2D31|rcsb pdb:2DYP|rcsb pdb:3SHV|rcsb pdb:3SQD|rcsb pdb:3SZM|rcsb pdb:3U3Z|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:e39O++wYwPAUlKUeNfRurqnXbz09606 rogid:VQoEp3F8lEBTOj+PDDUzrJCQNZA9606 rigid:0wLl6vlOSheulenMZqgylDdc8Mw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96GD3 uniprotkb:O95503 intact:EBI-713793|uniprotkb:Q5VT76|uniprotkb:Q6IAJ4|uniprotkb:Q8WU48|uniprotkb:Q9UKM5|uniprotkb:Q9UKM6|ensembl:ENSP00000318094|ensembl:ENSP00000380359|uniprotkb:B4DRQ8 intact:EBI-3951758|uniprotkb:A8KAH0|uniprotkb:Q96EM5|intact:EBI-28986885|ensembl:ENSP00000384490 psi-mi:scmh1_human(display_long)|uniprotkb:Sex comb on midleg homolog 1(gene name synonym)|uniprotkb:SCMH1(gene name)|psi-mi:SCMH1(display_short) psi-mi:cbx6_human(display_long)|uniprotkb:CBX6(gene name)|psi-mi:CBX6(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484312|imex:IM-26985-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006710527.1|ensembl:ENSG00000010803(gene)|ensembl:ENST00000326197(transcript)|ensembl:ENST00000397174(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010369"(chromocenter)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|go:"GO:0005634"(nucleus)|interpro:IPR021987|interpro:IPR033763|interpro:IPR038348|mint:Q96GD3|rcsb pdb:2P0K|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|refseq:NP_001026864.1|refseq:NP_001165689.1|refseq:NP_001165690.1|refseq:NP_001165691.1|refseq:NP_001165692.1|refseq:NP_001165693.1|refseq:NP_036368.1|refseq:XP_016856188.1|refseq:XP_016856196.1|refseq:XP_011539335.1|refseq:XP_011539338.1 refseq:NP_001290423.1|ensembl:ENSG00000183741(gene)|refseq:NP_055107.3|ensembl:ENST00000407418(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0031519"(PcG protein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|mint:O95503|rcsb pdb:3GV6|rcsb pdb:3I90|reactome:R-HSA-2559580|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSP00000384490|dip:DIP-48605N - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:e39O++wYwPAUlKUeNfRurqnXbz09606 rogid:4iNHCYe1bjb/JcurXP1iGoO/2uA9606 rigid:0wLl6vlOSheulenMZqgylDdc8Mw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96GD3 uniprotkb:Q6SPF0 intact:EBI-713793|uniprotkb:Q5VT76|uniprotkb:Q6IAJ4|uniprotkb:Q8WU48|uniprotkb:Q9UKM5|uniprotkb:Q9UKM6|ensembl:ENSP00000318094|ensembl:ENSP00000380359|uniprotkb:B4DRQ8 intact:EBI-8833536|uniprotkb:Q96IM4|uniprotkb:Q6PIS7|uniprotkb:Q6P0R3 psi-mi:scmh1_human(display_long)|uniprotkb:Sex comb on midleg homolog 1(gene name synonym)|uniprotkb:SCMH1(gene name)|psi-mi:SCMH1(display_short) psi-mi:samd1_human(display_long)|uniprotkb:SAMD1(gene name)|psi-mi:SAMD1(display_short)|uniprotkb:Atherin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484312|imex:IM-26985-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006710527.1|ensembl:ENSG00000010803(gene)|ensembl:ENST00000326197(transcript)|ensembl:ENST00000397174(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010369"(chromocenter)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|go:"GO:0005634"(nucleus)|interpro:IPR021987|interpro:IPR033763|interpro:IPR038348|mint:Q96GD3|rcsb pdb:2P0K|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|refseq:NP_001026864.1|refseq:NP_001165689.1|refseq:NP_001165690.1|refseq:NP_001165691.1|refseq:NP_001165692.1|refseq:NP_001165693.1|refseq:NP_036368.1|refseq:XP_016856188.1|refseq:XP_016856196.1|refseq:XP_011539335.1|refseq:XP_011539338.1 mint:Q6SPF0|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_612361.1|go:"GO:0005737"(cytoplasm)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|rcsb pdb:6LUI|rcsb pdb:6LUJ|rcsb pdb:6LUK|go:"GO:0003682"(chromatin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus) - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:e39O++wYwPAUlKUeNfRurqnXbz09606 rogid:Cav/ZfHiZJ1xCBI6jAYrzv+CmZ49606 rigid:0wLl6vlOSheulenMZqgylDdc8Mw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96GD3 uniprotkb:Q9UQR0 intact:EBI-713793|uniprotkb:Q5VT76|uniprotkb:Q6IAJ4|uniprotkb:Q8WU48|uniprotkb:Q9UKM5|uniprotkb:Q9UKM6|ensembl:ENSP00000318094|ensembl:ENSP00000380359|uniprotkb:B4DRQ8 intact:EBI-2513111|ensembl:ENSP00000251900|uniprotkb:Q8IWD0|uniprotkb:Q86U98|uniprotkb:Q8NDP2|uniprotkb:Q9UGC5|uniprotkb:Q5JXE6 psi-mi:scmh1_human(display_long)|uniprotkb:Sex comb on midleg homolog 1(gene name synonym)|uniprotkb:SCMH1(gene name)|psi-mi:SCMH1(display_short) psi-mi:scml2_human(display_long)|uniprotkb:SCML2(gene name)|psi-mi:SCML2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484312|imex:IM-26985-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006710527.1|ensembl:ENSG00000010803(gene)|ensembl:ENST00000326197(transcript)|ensembl:ENST00000397174(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010369"(chromocenter)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|go:"GO:0005634"(nucleus)|interpro:IPR021987|interpro:IPR033763|interpro:IPR038348|mint:Q96GD3|rcsb pdb:2P0K|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|refseq:NP_001026864.1|refseq:NP_001165689.1|refseq:NP_001165690.1|refseq:NP_001165691.1|refseq:NP_001165692.1|refseq:NP_001165693.1|refseq:NP_036368.1|refseq:XP_016856188.1|refseq:XP_016856196.1|refseq:XP_011539335.1|refseq:XP_011539338.1 ensembl:ENSG00000102098(gene)|ensembl:ENST00000251900(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0031519"(PcG protein complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR033763|interpro:IPR038348|mint:Q9UQR0|rcsb pdb:1OI1|rcsb pdb:2BIV|rcsb pdb:2MEM|rcsb pdb:2VYT|rcsb pdb:4EDU|refseq:NP_006080.1|refseq:XP_016884708.1|refseq:XP_016884709.1|dip:DIP-53760N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:e39O++wYwPAUlKUeNfRurqnXbz09606 rogid:6nmElZ2VXM/O5RZx+i1iu9JnsK09606 rigid:0wLl6vlOSheulenMZqgylDdc8Mw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96GD3 uniprotkb:O00257 intact:EBI-713793|uniprotkb:Q5VT76|uniprotkb:Q6IAJ4|uniprotkb:Q8WU48|uniprotkb:Q9UKM5|uniprotkb:Q9UKM6|ensembl:ENSP00000318094|ensembl:ENSP00000380359|uniprotkb:B4DRQ8 intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397 psi-mi:scmh1_human(display_long)|uniprotkb:Sex comb on midleg homolog 1(gene name synonym)|uniprotkb:SCMH1(gene name)|psi-mi:SCMH1(display_short) psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484312|imex:IM-26985-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006710527.1|ensembl:ENSG00000010803(gene)|ensembl:ENST00000326197(transcript)|ensembl:ENST00000397174(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010369"(chromocenter)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|go:"GO:0005634"(nucleus)|interpro:IPR021987|interpro:IPR033763|interpro:IPR038348|mint:Q96GD3|rcsb pdb:2P0K|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|refseq:NP_001026864.1|refseq:NP_001165689.1|refseq:NP_001165690.1|refseq:NP_001165691.1|refseq:NP_001165692.1|refseq:NP_001165693.1|refseq:NP_036368.1|refseq:XP_016856188.1|refseq:XP_016856196.1|refseq:XP_011539335.1|refseq:XP_011539338.1 refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:e39O++wYwPAUlKUeNfRurqnXbz09606 rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606 rigid:0wLl6vlOSheulenMZqgylDdc8Mw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96GD3 uniprotkb:Q14781 intact:EBI-713793|uniprotkb:Q5VT76|uniprotkb:Q6IAJ4|uniprotkb:Q8WU48|uniprotkb:Q9UKM5|uniprotkb:Q9UKM6|ensembl:ENSP00000318094|ensembl:ENSP00000380359|uniprotkb:B4DRQ8 intact:EBI-745934|uniprotkb:Q9BTB1|uniprotkb:Q0VDA5|ensembl:ENSP00000308750 psi-mi:scmh1_human(display_long)|uniprotkb:Sex comb on midleg homolog 1(gene name synonym)|uniprotkb:SCMH1(gene name)|psi-mi:SCMH1(display_short) psi-mi:cbx2_human(display_long)|uniprotkb:CBX2(gene name)|psi-mi:CBX2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484312|imex:IM-26985-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006710527.1|ensembl:ENSG00000010803(gene)|ensembl:ENST00000326197(transcript)|ensembl:ENST00000397174(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010369"(chromocenter)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|go:"GO:0005634"(nucleus)|interpro:IPR021987|interpro:IPR033763|interpro:IPR038348|mint:Q96GD3|rcsb pdb:2P0K|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|refseq:NP_001026864.1|refseq:NP_001165689.1|refseq:NP_001165690.1|refseq:NP_001165691.1|refseq:NP_001165692.1|refseq:NP_001165693.1|refseq:NP_036368.1|refseq:XP_016856188.1|refseq:XP_016856196.1|refseq:XP_011539335.1|refseq:XP_011539338.1 refseq:NP_005180.1|refseq:NP_116036.1|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|go:"GO:0045137"(development of primary sexual characteristics)|interpro:IPR042796|mint:Q14781|rcsb pdb:2D9U|rcsb pdb:3H91|rcsb pdb:5EPK|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|ensembl:ENSG00000173894(gene)|ensembl:ENST00000310942(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0030154"(cell differentiation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|dip:DIP-48604N - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:e39O++wYwPAUlKUeNfRurqnXbz09606 rogid:220eC8UGlmAHHP2WAhZdAveHC3s9606 rigid:0wLl6vlOSheulenMZqgylDdc8Mw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96GD3 uniprotkb:P35226 intact:EBI-713793|uniprotkb:Q5VT76|uniprotkb:Q6IAJ4|uniprotkb:Q8WU48|uniprotkb:Q9UKM5|uniprotkb:Q9UKM6|ensembl:ENSP00000318094|ensembl:ENSP00000380359|uniprotkb:B4DRQ8 intact:EBI-2341576|uniprotkb:Q5T8Z3|uniprotkb:Q96F37|uniprotkb:Q16030|intact:EBI-28989037|ensembl:ENSP00000365851 psi-mi:scmh1_human(display_long)|uniprotkb:Sex comb on midleg homolog 1(gene name synonym)|uniprotkb:SCMH1(gene name)|psi-mi:SCMH1(display_short) psi-mi:bmi1_human(display_long)|uniprotkb:BMI1(gene name)|psi-mi:BMI1(display_short)|uniprotkb:PCGF4(gene name synonym)|uniprotkb:RNF51(gene name synonym)|uniprotkb:Polycomb group RING finger protein 4(gene name synonym)|uniprotkb:RING finger protein 51(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484312|imex:IM-26985-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006710527.1|ensembl:ENSG00000010803(gene)|ensembl:ENST00000326197(transcript)|ensembl:ENST00000397174(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010369"(chromocenter)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|go:"GO:0005634"(nucleus)|interpro:IPR021987|interpro:IPR033763|interpro:IPR038348|mint:Q96GD3|rcsb pdb:2P0K|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|refseq:NP_001026864.1|refseq:NP_001165689.1|refseq:NP_001165690.1|refseq:NP_001165691.1|refseq:NP_001165692.1|refseq:NP_001165693.1|refseq:NP_036368.1|refseq:XP_016856188.1|refseq:XP_016856196.1|refseq:XP_011539335.1|refseq:XP_011539338.1 refseq:NP_001190991.1|refseq:NP_005171.4|ensembl:ENSP00000365851|dip:DIP-41879N|ensembl:ENSG00000168283(gene)|ensembl:ENST00000376663(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006959"(humoral immune response)|go:"GO:0007379"(segment specification)|go:"GO:0007420"(brain development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35226|rcsb pdb:2H0D|rcsb pdb:2NA1|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:5FR6|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 - - comment:"author score: 29" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:e39O++wYwPAUlKUeNfRurqnXbz09606 rogid:ruyez2gHfd/si8gxYUDZzZ1L4689606 rigid:0wLl6vlOSheulenMZqgylDdc8Mw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96GD3 uniprotkb:P35227 intact:EBI-713793|uniprotkb:Q5VT76|uniprotkb:Q6IAJ4|uniprotkb:Q8WU48|uniprotkb:Q9UKM5|uniprotkb:Q9UKM6|ensembl:ENSP00000318094|ensembl:ENSP00000380359|uniprotkb:B4DRQ8 intact:EBI-2129767|uniprotkb:A6NGD8|ensembl:ENSP00000478517|ensembl:ENSP00000478970|ensembl:ENSP00000482063|ensembl:ENSP00000482815|ensembl:ENSP00000488868|ensembl:ENSP00000488872 psi-mi:scmh1_human(display_long)|uniprotkb:Sex comb on midleg homolog 1(gene name synonym)|uniprotkb:SCMH1(gene name)|psi-mi:SCMH1(display_short) psi-mi:pcgf2_human(display_long)|uniprotkb:PCGF2(gene name)|psi-mi:PCGF2(display_short)|uniprotkb:MEL18(gene name synonym)|uniprotkb:RNF110(gene name synonym)|uniprotkb:ZNF144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484312|imex:IM-26985-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006710527.1|ensembl:ENSG00000010803(gene)|ensembl:ENST00000326197(transcript)|ensembl:ENST00000397174(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010369"(chromocenter)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|go:"GO:0005634"(nucleus)|interpro:IPR021987|interpro:IPR033763|interpro:IPR038348|mint:Q96GD3|rcsb pdb:2P0K|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|refseq:NP_001026864.1|refseq:NP_001165689.1|refseq:NP_001165690.1|refseq:NP_001165691.1|refseq:NP_001165692.1|refseq:NP_001165693.1|refseq:NP_036368.1|refseq:XP_016856188.1|refseq:XP_016856196.1|refseq:XP_011539335.1|refseq:XP_011539338.1 refseq:NP_009075.1|refseq:XP_016880505.1|refseq:XP_005257697.1|refseq:XP_005257698.1|refseq:XP_005257699.1|dip:DIP-41880N|ensembl:ENSG00000277258(gene)|ensembl:ENSG00000278644(gene)|ensembl:ENST00000610440(transcript)|ensembl:ENST00000611883(transcript)|ensembl:ENST00000616199(transcript)|ensembl:ENST00000620225(transcript)|ensembl:ENST00000631566(transcript)|ensembl:ENST00000631610(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35227|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-5617472|reactome:R-HSA-8953750 - - comment:"author score: 30" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:e39O++wYwPAUlKUeNfRurqnXbz09606 rogid:zppw56VrEl6gEFwtJMCN5cQkPxI9606 rigid:0wLl6vlOSheulenMZqgylDdc8Mw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96GD3 uniprotkb:P78364 intact:EBI-713793|uniprotkb:Q5VT76|uniprotkb:Q6IAJ4|uniprotkb:Q8WU48|uniprotkb:Q9UKM5|uniprotkb:Q9UKM6|ensembl:ENSP00000318094|ensembl:ENSP00000380359|uniprotkb:B4DRQ8 intact:EBI-725403|uniprotkb:Q8WVM3|uniprotkb:Q9BU63|uniprotkb:D3DUV4|ensembl:ENSP00000437659|ensembl:ENSP00000440674 psi-mi:scmh1_human(display_long)|uniprotkb:Sex comb on midleg homolog 1(gene name synonym)|uniprotkb:SCMH1(gene name)|psi-mi:SCMH1(display_short) psi-mi:phc1_human(display_long)|uniprotkb:Early development regulatory protein 1(gene name synonym)|uniprotkb:PHC1(gene name)|psi-mi:PHC1(display_short)|uniprotkb:EDR1(gene name synonym)|uniprotkb:PH1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484312|imex:IM-26985-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006710527.1|ensembl:ENSG00000010803(gene)|ensembl:ENST00000326197(transcript)|ensembl:ENST00000397174(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010369"(chromocenter)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|go:"GO:0005634"(nucleus)|interpro:IPR021987|interpro:IPR033763|interpro:IPR038348|mint:Q96GD3|rcsb pdb:2P0K|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|refseq:NP_001026864.1|refseq:NP_001165689.1|refseq:NP_001165690.1|refseq:NP_001165691.1|refseq:NP_001165692.1|refseq:NP_001165693.1|refseq:NP_036368.1|refseq:XP_016856188.1|refseq:XP_016856196.1|refseq:XP_011539335.1|refseq:XP_011539338.1 refseq:NP_004417.2|ensembl:ENSG00000111752(gene)|ensembl:ENST00000543824(transcript)|ensembl:ENST00000544916(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016574"(histone ubiquitination)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:P78364|rcsb pdb:2L8E|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|dip:DIP-44567N - - comment:"author score: 32" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:e39O++wYwPAUlKUeNfRurqnXbz09606 rogid:0dDjrgvWcP5Sx8h+qUj7awuM3ko9606 rigid:0wLl6vlOSheulenMZqgylDdc8Mw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96GD3 uniprotkb:Q99496 intact:EBI-713793|uniprotkb:Q5VT76|uniprotkb:Q6IAJ4|uniprotkb:Q8WU48|uniprotkb:Q9UKM5|uniprotkb:Q9UKM6|ensembl:ENSP00000318094|ensembl:ENSP00000380359|uniprotkb:B4DRQ8 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:scmh1_human(display_long)|uniprotkb:Sex comb on midleg homolog 1(gene name synonym)|uniprotkb:SCMH1(gene name)|psi-mi:SCMH1(display_short) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484312|imex:IM-26985-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006710527.1|ensembl:ENSG00000010803(gene)|ensembl:ENST00000326197(transcript)|ensembl:ENST00000397174(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010369"(chromocenter)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|go:"GO:0005634"(nucleus)|interpro:IPR021987|interpro:IPR033763|interpro:IPR038348|mint:Q96GD3|rcsb pdb:2P0K|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|refseq:NP_001026864.1|refseq:NP_001165689.1|refseq:NP_001165690.1|refseq:NP_001165691.1|refseq:NP_001165692.1|refseq:NP_001165693.1|refseq:NP_036368.1|refseq:XP_016856188.1|refseq:XP_016856196.1|refseq:XP_011539335.1|refseq:XP_011539338.1 refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 - - comment:"author score: 33" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:e39O++wYwPAUlKUeNfRurqnXbz09606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rigid:0wLl6vlOSheulenMZqgylDdc8Mw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96GD3 uniprotkb:Q8NDX5 intact:EBI-713793|uniprotkb:Q5VT76|uniprotkb:Q6IAJ4|uniprotkb:Q8WU48|uniprotkb:Q9UKM5|uniprotkb:Q9UKM6|ensembl:ENSP00000318094|ensembl:ENSP00000380359|uniprotkb:B4DRQ8 intact:EBI-1223801|uniprotkb:Q5HYF0|uniprotkb:Q6NSG2|uniprotkb:Q8NFT7|uniprotkb:Q8NFZ1|uniprotkb:Q8TBM2|uniprotkb:Q9H971|uniprotkb:Q9H9I4|uniprotkb:A2RRP9|ensembl:ENSP00000420271 psi-mi:scmh1_human(display_long)|uniprotkb:Sex comb on midleg homolog 1(gene name synonym)|uniprotkb:SCMH1(gene name)|psi-mi:SCMH1(display_short) psi-mi:phc3_human(display_long)|uniprotkb:PHC3(gene name)|psi-mi:PHC3(display_short)|uniprotkb:EDR3(gene name synonym)|uniprotkb:PH3(gene name synonym)|uniprotkb:Homolog of polyhomeotic 3(gene name synonym)|uniprotkb:Early development regulatory protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484312|imex:IM-26985-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006710527.1|ensembl:ENSG00000010803(gene)|ensembl:ENST00000326197(transcript)|ensembl:ENST00000397174(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010369"(chromocenter)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|go:"GO:0005634"(nucleus)|interpro:IPR021987|interpro:IPR033763|interpro:IPR038348|mint:Q96GD3|rcsb pdb:2P0K|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|refseq:NP_001026864.1|refseq:NP_001165689.1|refseq:NP_001165690.1|refseq:NP_001165691.1|refseq:NP_001165692.1|refseq:NP_001165693.1|refseq:NP_036368.1|refseq:XP_016856188.1|refseq:XP_016856196.1|refseq:XP_011539335.1|refseq:XP_011539338.1 refseq:NP_079223.3|refseq:NP_001295045.1|ensembl:ENSP00000420271|ensembl:ENST00000495893|ensembl:ENSP00000420294|ensembl:ENST00000497658|ensembl:ENSP00000420454|ensembl:ENSG00000173889(gene)|ensembl:ENST00000494943(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR038603|mint:Q8NDX5|rcsb pdb:4PZN|rcsb pdb:4PZO|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 - - comment:"author score: 35" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:e39O++wYwPAUlKUeNfRurqnXbz09606 rogid:hB1EMs+lCv19uuJ1O7+QiVCUoo89606 rigid:0wLl6vlOSheulenMZqgylDdc8Mw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96GD3 uniprotkb:Q8IXK0 intact:EBI-713793|uniprotkb:Q5VT76|uniprotkb:Q6IAJ4|uniprotkb:Q8WU48|uniprotkb:Q9UKM5|uniprotkb:Q9UKM6|ensembl:ENSP00000318094|ensembl:ENSP00000380359|uniprotkb:B4DRQ8 intact:EBI-713786|uniprotkb:Q8N306|uniprotkb:Q8TAG8|uniprotkb:A1L4Q1|uniprotkb:Q2TAL3|uniprotkb:Q5T0C1|uniprotkb:Q6NUJ6|uniprotkb:Q6ZQR1|uniprotkb:Q96BL4|uniprotkb:Q9Y4Y7|ensembl:ENSP00000257118|uniprotkb:D3DPR2|uniprotkb:A8KA40 psi-mi:scmh1_human(display_long)|uniprotkb:Sex comb on midleg homolog 1(gene name synonym)|uniprotkb:SCMH1(gene name)|psi-mi:SCMH1(display_short) psi-mi:phc2_human(display_long)|uniprotkb:Early development regulatory protein 2(gene name synonym)|uniprotkb:PHC2(gene name)|psi-mi:PHC2(display_short)|uniprotkb:EDR2(gene name synonym)|uniprotkb:PH2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484312|imex:IM-26985-53 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006710527.1|ensembl:ENSG00000010803(gene)|ensembl:ENST00000326197(transcript)|ensembl:ENST00000397174(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010369"(chromocenter)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|go:"GO:0005634"(nucleus)|interpro:IPR021987|interpro:IPR033763|interpro:IPR038348|mint:Q96GD3|rcsb pdb:2P0K|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|refseq:NP_001026864.1|refseq:NP_001165689.1|refseq:NP_001165690.1|refseq:NP_001165691.1|refseq:NP_001165692.1|refseq:NP_001165693.1|refseq:NP_036368.1|refseq:XP_016856188.1|refseq:XP_016856196.1|refseq:XP_011539335.1|refseq:XP_011539338.1 interpro:IPR038603|mint:Q8IXK0|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|interpro:IPR013761(Sterile alpha motif-type)|ensembl:ENSG00000134686(gene)|ensembl:ENST00000257118(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR012313(Zinc finger, FCS-type)|refseq:NP_004418.2|refseq:NP_932157.1|refseq:XP_016856005.1|refseq:XP_016856006.1|refseq:XP_016856007.1|refseq:XP_005270627.1|dip:DIP-34464N - - comment:"author score: 40" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:e39O++wYwPAUlKUeNfRurqnXbz09606 rogid:7si/KU2tHoxviuCr70ncQERDWmY9606 rigid:0wLl6vlOSheulenMZqgylDdc8Mw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UPW6 uniprotkb:P35030 intact:EBI-8298169|ensembl:ENSP00000260926|ensembl:ENSP00000401112|ensembl:ENSP00000405420|uniprotkb:Q3ZB87|uniprotkb:Q4V763|intact:MINT-2822679|uniprotkb:A8K5Z8 intact:EBI-1221209|uniprotkb:Q5VXV0|intact:EBI-2825937|uniprotkb:A8CED3|uniprotkb:F8W7P3|uniprotkb:Q6ISJ4|uniprotkb:P15951|uniprotkb:Q15665|uniprotkb:Q9UQV3|uniprotkb:A9Z1Y4|uniprotkb:E7ES07|uniprotkb:A8CED1 psi-mi:satb2_human(display_long)|uniprotkb:SATB2(gene name)|psi-mi:SATB2(display_short)|uniprotkb:KIAA1034(gene name synonym)|uniprotkb:Special AT-rich sequence-binding protein 2(gene name synonym) psi-mi:try3_human(display_long)|uniprotkb:PRSS3(gene name)|psi-mi:PRSS3(display_short)|uniprotkb:PRSS4(gene name synonym)|uniprotkb:TRY3(gene name synonym)|uniprotkb:TRY4(gene name synonym)|uniprotkb:Trypsin III(gene name synonym)|uniprotkb:Brain trypsinogen(gene name synonym)|uniprotkb:Mesotrypsinogen(gene name synonym)|uniprotkb:Trypsin IV(gene name synonym)|uniprotkb:Serine protease 3(gene name synonym)|uniprotkb:Serine protease 4(gene name synonym)|uniprotkb:Mesotrypsin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484297|imex:IM-26985-129 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000119042(gene)|ensembl:ENST00000260926(transcript)|ensembl:ENST00000417098(transcript)|ensembl:ENST00000457245(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002076"(osteoblast development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021902"(commitment of neuronal cell to specific neuron type in forebrain)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071310"(cellular response to organic substance)|interpro:IPR001356(Homeobox)|interpro:IPR003350(Homeodomain protein CUT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR032355|interpro:IPR032392|interpro:IPR038216|interpro:IPR038224|interpro:IPR039673|mint:Q9UPW6|rcsb pdb:1WI3|rcsb pdb:1WIZ|rcsb pdb:2CSF|reactome:R-HSA-4551638|reactome:R-HSA-8940973|refseq:XP_011509142.1|refseq:XP_006712435.1|refseq:NP_001165988.1|refseq:NP_001165980.1|refseq:NP_056080.1|dip:DIP-60551N refseq:NP_002762.2|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|refseq:NP_001184026.2|refseq:NP_031369.2|refseq:NP_001184027.1|mint:P35030|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0007586"(digestion)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0031638"(zymogen activation)|go:"GO:0043542"(endothelial cell migration)|go:"GO:1904724"(tertiary granule lumen)|rcsb pdb:1H4W|rcsb pdb:2R9P|rcsb pdb:3L33|rcsb pdb:3L3T|rcsb pdb:3P92|rcsb pdb:3P95|rcsb pdb:4DG4|rcsb pdb:4U30|rcsb pdb:4U32|rcsb pdb:5C67|rcsb pdb:5JBT|rcsb pdb:5TP0|rcsb pdb:6BX8|rcsb pdb:6GFI|reactome:R-HSA-1462054|reactome:R-HSA-196741|reactome:R-HSA-6798695|reactome:R-HSA-6803157|interpro:IPR043504 - comment:mint|function:May play an important role in palate formation|function:"Chromosomal aberrations involving SATB2 are found in isolated cleft palate. Translocation t(2;7); translocation t(2;11)"|function:"Defects in SATB2 are the cause of isolated cleft palate with mental retardation [MIM:119540]. Patients manifest cleft palate, craniofacial dysmorphism and profound mental retardation" comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/dQFGKi08prg2Xjhsj4sqW77Cl09606 rogid:AEfz7orXeNoasizB5N76AkF4WMk9606 rigid:zMHiT+c2J9ZHoNGaiKN1gJEo+ho false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UPW6 uniprotkb:P53350 intact:EBI-8298169|ensembl:ENSP00000260926|ensembl:ENSP00000401112|ensembl:ENSP00000405420|uniprotkb:Q3ZB87|uniprotkb:Q4V763|intact:MINT-2822679|uniprotkb:A8K5Z8 intact:EBI-476768|uniprotkb:Q15153|uniprotkb:Q99746|ensembl:ENSP00000300093 psi-mi:satb2_human(display_long)|uniprotkb:SATB2(gene name)|psi-mi:SATB2(display_short)|uniprotkb:KIAA1034(gene name synonym)|uniprotkb:Special AT-rich sequence-binding protein 2(gene name synonym) psi-mi:plk1_human(display_long)|uniprotkb:Polo-like kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 13(gene name synonym)|uniprotkb:PLK1(gene name)|psi-mi:PLK1(display_short)|uniprotkb:PLK(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484297|imex:IM-26985-129 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000119042(gene)|ensembl:ENST00000260926(transcript)|ensembl:ENST00000417098(transcript)|ensembl:ENST00000457245(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002076"(osteoblast development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021902"(commitment of neuronal cell to specific neuron type in forebrain)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071310"(cellular response to organic substance)|interpro:IPR001356(Homeobox)|interpro:IPR003350(Homeodomain protein CUT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR032355|interpro:IPR032392|interpro:IPR038216|interpro:IPR038224|interpro:IPR039673|mint:Q9UPW6|rcsb pdb:1WI3|rcsb pdb:1WIZ|rcsb pdb:2CSF|reactome:R-HSA-4551638|reactome:R-HSA-8940973|refseq:XP_011509142.1|refseq:XP_006712435.1|refseq:NP_001165988.1|refseq:NP_001165980.1|refseq:NP_056080.1|dip:DIP-60551N refseq:NP_005021.2|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045143"(homologous chromosome segregation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0051081"(nuclear membrane disassembly)|go:"GO:0051233"(spindle midzone)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070194"(synaptonemal complex disassembly)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0090435"(protein localization to nuclear envelope)|go:"GO:0097431"(mitotic spindle pole)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|ensembl:ENSG00000166851(gene)|ensembl:ENST00000300093(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000776"(kinetochore)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0007077"(mitotic nuclear membrane disassembly)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0005524"(ATP binding)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0010997"(anaphase-promoting complex binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030071"(regulation of mitotic metaphase/anaphase transition)|go:"GO:0030496"(midbody)|go:"GO:0031648"(protein destabilization)|rcsb pdb:4DFW|rcsb pdb:4E67|rcsb pdb:4E9C|rcsb pdb:4E9D|rcsb pdb:4H5X|rcsb pdb:4H71|rcsb pdb:4HAB|rcsb pdb:4HCO|rcsb pdb:4HY2|rcsb pdb:4J52|rcsb pdb:4J53|rcsb pdb:4LKL|rcsb pdb:4LKM|rcsb pdb:4O56|rcsb pdb:4O6W|rcsb pdb:4O9W|rcsb pdb:4RCP|rcsb pdb:4WHH|rcsb pdb:4WHK|rcsb pdb:4WHL|rcsb pdb:4X9R|rcsb pdb:4X9V|rcsb pdb:4X9W|rcsb pdb:5J19|rcsb pdb:5NEI|rcsb pdb:5NFU|rcsb pdb:5NJE|rcsb pdb:5NMM|rcsb pdb:5NN1|rcsb pdb:5NN2|rcsb pdb:5TA6|rcsb pdb:5TA8|rcsb pdb:6AX4|rcsb pdb:6GY2|reactome:R-HSA-141444|reactome:R-HSA-156711|reactome:R-HSA-162658|reactome:R-HSA-174178|reactome:R-HSA-176412|reactome:R-HSA-176417|reactome:R-HSA-2299718|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-2980767|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-68881|reactome:R-HSA-68884|reactome:R-HSA-69273|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-9648025|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1904776"(regulation of protein localization to cell cortex)|go:"GO:1905784"(regulation of anaphase-promoting complex-dependent catabolic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000959(POLO box duplicated region)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033695|interpro:IPR033701|interpro:IPR033702|interpro:IPR036947|mint:P53350|rcsb pdb:1Q4K|rcsb pdb:1Q4O|rcsb pdb:1UMW|rcsb pdb:2OGQ|rcsb pdb:2OJX|rcsb pdb:2OU7|rcsb pdb:2OWB|rcsb pdb:2RKU|rcsb pdb:2V5Q|rcsb pdb:2YAC|rcsb pdb:3BZI|rcsb pdb:3C5L|rcsb pdb:3FC2|rcsb pdb:3FVH|rcsb pdb:3HIH|rcsb pdb:3HIK|rcsb pdb:3KB7|rcsb pdb:3P2W|rcsb pdb:3P2Z|rcsb pdb:3P34|rcsb pdb:3P35|rcsb pdb:3P36|rcsb pdb:3P37|rcsb pdb:3Q1I|rcsb pdb:3RQ7|rcsb pdb:3THB|rcsb pdb:4A4L|rcsb pdb:4A4O|dip:DIP-29696N - comment:mint|function:May play an important role in palate formation|function:"Chromosomal aberrations involving SATB2 are found in isolated cleft palate. Translocation t(2;7); translocation t(2;11)"|function:"Defects in SATB2 are the cause of isolated cleft palate with mental retardation [MIM:119540]. Patients manifest cleft palate, craniofacial dysmorphism and profound mental retardation" comment:"author score: 47" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/dQFGKi08prg2Xjhsj4sqW77Cl09606 rogid:fBOK366hV6mDprx9IWhz43gPcJE9606 rigid:zMHiT+c2J9ZHoNGaiKN1gJEo+ho false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UPW6 uniprotkb:Q96LD4 intact:EBI-8298169|ensembl:ENSP00000260926|ensembl:ENSP00000401112|ensembl:ENSP00000405420|uniprotkb:Q3ZB87|uniprotkb:Q4V763|intact:MINT-2822679|uniprotkb:A8K5Z8 intact:EBI-2130423|uniprotkb:Q96GU5|uniprotkb:Q9BRN7|uniprotkb:Q96AD0|intact:EBI-28987808|ensembl:ENSP00000254816 psi-mi:satb2_human(display_long)|uniprotkb:SATB2(gene name)|psi-mi:SATB2(display_short)|uniprotkb:KIAA1034(gene name synonym)|uniprotkb:Special AT-rich sequence-binding protein 2(gene name synonym) psi-mi:tri47_human(display_long)|uniprotkb:TRIM47(gene name)|psi-mi:TRIM47(display_short)|uniprotkb:GOA(gene name synonym)|uniprotkb:RNF100(gene name synonym)|uniprotkb:Gene overexpressed in astrocytoma protein(gene name synonym)|uniprotkb:RING finger protein 100(gene name synonym)|uniprotkb:Tripartite motif-containing protein 47(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484297|imex:IM-26985-129 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000119042(gene)|ensembl:ENST00000260926(transcript)|ensembl:ENST00000417098(transcript)|ensembl:ENST00000457245(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001764"(neuron migration)|go:"GO:0002076"(osteoblast development)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009880"(embryonic pattern specification)|go:"GO:0016363"(nuclear matrix)|go:"GO:0021902"(commitment of neuronal cell to specific neuron type in forebrain)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051216"(cartilage development)|go:"GO:0060021"(roof of mouth development)|go:"GO:0071310"(cellular response to organic substance)|interpro:IPR001356(Homeobox)|interpro:IPR003350(Homeodomain protein CUT)|interpro:IPR009057(Homeodomain-like)|interpro:IPR010982(Lambda repressor-like, DNA-binding)|interpro:IPR032355|interpro:IPR032392|interpro:IPR038216|interpro:IPR038224|interpro:IPR039673|mint:Q9UPW6|rcsb pdb:1WI3|rcsb pdb:1WIZ|rcsb pdb:2CSF|reactome:R-HSA-4551638|reactome:R-HSA-8940973|refseq:XP_011509142.1|refseq:XP_006712435.1|refseq:NP_001165988.1|refseq:NP_001165980.1|refseq:NP_056080.1|dip:DIP-60551N refseq:NP_258411.2|ensembl:ENSP00000254816|refseq:XP_005257844.1|refseq:XP_005257845.1|ensembl:ENSG00000132481(gene)|ensembl:ENST00000254816(transcript)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR042780|interpro:IPR043136|mint:Q96LD4 - comment:mint|function:May play an important role in palate formation|function:"Chromosomal aberrations involving SATB2 are found in isolated cleft palate. Translocation t(2;7); translocation t(2;11)"|function:"Defects in SATB2 are the cause of isolated cleft palate with mental retardation [MIM:119540]. Patients manifest cleft palate, craniofacial dysmorphism and profound mental retardation" comment:"author score: 53" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/dQFGKi08prg2Xjhsj4sqW77Cl09606 rogid:F8KSNivuNkLAEFW/DrYsMu5ICRk9606 rigid:zMHiT+c2J9ZHoNGaiKN1gJEo+ho false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35244 uniprotkb:P35251 intact:EBI-621428|ensembl:ENSP00000223129|ensembl:ENSP00000379914|uniprotkb:Q549U6|intact:EBI-1058317 intact:EBI-476616|uniprotkb:Q5XKF5|uniprotkb:Q6PKU0|uniprotkb:Q86V41|uniprotkb:Q86V46|ensembl:ENSP00000371321|uniprotkb:A8K6E7 psi-mi:rfa3_human(display_long)|uniprotkb:Replication factor A protein 3(gene name synonym)|uniprotkb:RPA3(gene name)|psi-mi:RPA3(display_short)|uniprotkb:REPA3(gene name synonym)|uniprotkb:RPA14(gene name synonym) psi-mi:rfc1_human(display_long)|uniprotkb:Activator 1 subunit 1(gene name synonym)|uniprotkb:Replication factor C large subunit(gene name synonym)|uniprotkb:Replication factor C 140 kDa subunit(gene name synonym)|uniprotkb:Activator 1 140 kDa subunit(gene name synonym)|uniprotkb:Activator 1 large subunit(gene name synonym)|uniprotkb:DNA-binding protein PO-GA(gene name synonym)|uniprotkb:RFC1(gene name)|psi-mi:RFC1(display_short)|uniprotkb:RFC140(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483961|imex:IM-26985-573 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0035861"(site of double-strand break)|ensembl:ENSG00000106399(gene)|go:"GO:0042127"(regulation of cell population proliferation)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013970(Replication factor A protein 3)|mint:P35244|rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|ensembl:ENST00000223129(transcript)|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|ensembl:ENST00000396682(transcript)|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|refseq:NP_002938.1|dip:DIP-24190N refseq:NP_001191676.1|refseq:NP_002904.3|ensembl:ENSG00000035928(gene)|ensembl:ENST00000381897(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003689"(DNA clamp loader activity)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031391"(Elg1 RFC-like complex)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0061860"(DNA clamp unloader activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090618"(DNA clamp unloading)|interpro:IPR001357(BRCT)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR012178(DNA replication factor C, large subunit)|interpro:IPR013725(DNA replication factor RFC1, C-terminal)|interpro:IPR027417|interpro:IPR036420|mint:P35251|rcsb pdb:2EBU|rcsb pdb:2K6G|rcsb pdb:2K7F|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685942|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-69091 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:hHO7MxGGHUjz30HXSBZd9cXOq6I9606 rogid:m4MUwhmpn0xCElyHLAw4FlIVyBs9606 rigid:m51TsuiKprkaRBr1V5K/Qd+ZCyY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35244 uniprotkb:P35249 intact:EBI-621428|ensembl:ENSP00000223129|ensembl:ENSP00000379914|uniprotkb:Q549U6|intact:EBI-1058317 intact:EBI-476655|uniprotkb:Q6FHX7|ensembl:ENSP00000296273|ensembl:ENSP00000376272|uniprotkb:D3DNV2|uniprotkb:B4DM41 psi-mi:rfa3_human(display_long)|uniprotkb:Replication factor A protein 3(gene name synonym)|uniprotkb:RPA3(gene name)|psi-mi:RPA3(display_short)|uniprotkb:REPA3(gene name synonym)|uniprotkb:RPA14(gene name synonym) psi-mi:rfc4_human(display_long)|uniprotkb:Activator 1 subunit 4(gene name synonym)|uniprotkb:Replication factor C 37 kDa subunit(gene name synonym)|uniprotkb:Activator 1 37 kDa subunit(gene name synonym)|uniprotkb:RFC4(gene name)|psi-mi:RFC4(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483961|imex:IM-26985-573 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0035861"(site of double-strand break)|ensembl:ENSG00000106399(gene)|go:"GO:0042127"(regulation of cell population proliferation)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013970(Replication factor A protein 3)|mint:P35244|rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|ensembl:ENST00000223129(transcript)|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|ensembl:ENST00000396682(transcript)|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|refseq:NP_002938.1|dip:DIP-24190N refseq:NP_002907.1|refseq:NP_853551.1|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|ensembl:ENSG00000163918(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006271"(DNA strand elongation involved in DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0031391"(Elg1 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|ensembl:ENST00000296273(transcript)|ensembl:ENST00000392481(transcript)|mint:P35249|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804756|reactome:R-HSA-69091|reactome:R-HSA-69473|reactome:R-HSA-176187|dip:DIP-24267N - - comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:hHO7MxGGHUjz30HXSBZd9cXOq6I9606 rogid:zn+V998ZRpYIdHmG87ExC6LFc0w9606 rigid:m51TsuiKprkaRBr1V5K/Qd+ZCyY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35244 uniprotkb:P35250 intact:EBI-621428|ensembl:ENSP00000223129|ensembl:ENSP00000379914|uniprotkb:Q549U6|intact:EBI-1058317 intact:EBI-476409|uniprotkb:P32846|uniprotkb:Q9BU93|uniprotkb:D3DXG3|ensembl:ENSP00000055077|uniprotkb:B5BU07 psi-mi:rfa3_human(display_long)|uniprotkb:Replication factor A protein 3(gene name synonym)|uniprotkb:RPA3(gene name)|psi-mi:RPA3(display_short)|uniprotkb:REPA3(gene name synonym)|uniprotkb:RPA14(gene name synonym) psi-mi:rfc2_human(display_long)|uniprotkb:Activator 1 subunit 2(gene name synonym)|uniprotkb:Replication factor C 40 kDa subunit(gene name synonym)|uniprotkb:Activator 1 40 kDa subunit(gene name synonym)|uniprotkb:RFC2(gene name)|psi-mi:RFC2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483961|imex:IM-26985-573 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0035861"(site of double-strand break)|ensembl:ENSG00000106399(gene)|go:"GO:0042127"(regulation of cell population proliferation)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013970(Replication factor A protein 3)|mint:P35244|rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|ensembl:ENST00000223129(transcript)|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|ensembl:ENST00000396682(transcript)|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|refseq:NP_002938.1|dip:DIP-24190N ensembl:ENSG00000049541(gene)|ensembl:ENST00000055077(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0019899"(enzyme binding)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|mint:P35250|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-176187|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804756|reactome:R-HSA-69091|reactome:R-HSA-69473|refseq:NP_002905.2|refseq:NP_852136.1|refseq:NP_001265720.1|refseq:NP_001265721.1|refseq:NP_001265722.1|dip:DIP-34367N - - comment:"author score: 33" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:hHO7MxGGHUjz30HXSBZd9cXOq6I9606 rogid:36ppRbKXusdkqhmmoOTQ04BWv6I9606 rigid:m51TsuiKprkaRBr1V5K/Qd+ZCyY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35244 uniprotkb:Q96FZ2 intact:EBI-621428|ensembl:ENSP00000223129|ensembl:ENSP00000379914|uniprotkb:Q549U6|intact:EBI-1058317 intact:EBI-5463169|uniprotkb:A6NJR9|uniprotkb:Q96G34|uniprotkb:Q9NRP3|ensembl:ENSP00000372955|ensembl:ENSP00000374385|ensembl:ENSP00000426215 psi-mi:rfa3_human(display_long)|uniprotkb:Replication factor A protein 3(gene name synonym)|uniprotkb:RPA3(gene name)|psi-mi:RPA3(display_short)|uniprotkb:REPA3(gene name synonym)|uniprotkb:RPA14(gene name synonym) psi-mi:hmces_human(display_long)|uniprotkb:Peptidase HMCES(gene name synonym)|uniprotkb:HMCES(gene name)|psi-mi:HMCES(display_short)|uniprotkb:C3orf37(gene name synonym)|uniprotkb:DC12(gene name synonym)|uniprotkb:SRAP domain-containing protein 1(gene name synonym)|uniprotkb:SRAPD1(gene name synonym)|uniprotkb:Embryonic stem cell-specific 5-hydroxymethylcytosine-binding protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483961|imex:IM-26985-573 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0035861"(site of double-strand break)|ensembl:ENSG00000106399(gene)|go:"GO:0042127"(regulation of cell population proliferation)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013970(Replication factor A protein 3)|mint:P35244|rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|ensembl:ENST00000223129(transcript)|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|ensembl:ENST00000396682(transcript)|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|refseq:NP_002938.1|dip:DIP-24190N refseq:NP_001006109.1|refseq:NP_064572.2|refseq:XP_005247693.1|refseq:XP_016862366.1|ensembl:ENSG00000183624(gene)|ensembl:ENST00000383463(transcript)|ensembl:ENST00000389735(transcript)|ensembl:ENST00000502878(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005657"(replication fork)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008233"(peptidase activity)|go:"GO:0018142"(protein-DNA covalent cross-linking)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR003738(Protein of unknown function DUF159)|interpro:IPR036590|mint:Q96FZ2|rcsb pdb:5KO9|rcsb pdb:6OE7|rcsb pdb:6OEA|rcsb pdb:6OEB|rcsb pdb:6OOV - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:hHO7MxGGHUjz30HXSBZd9cXOq6I9606 rogid:RUxL4I/0cIkV8okqQ2y6RZUgsqo9606 rigid:m51TsuiKprkaRBr1V5K/Qd+ZCyY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35244 uniprotkb:Q8N8A6 intact:EBI-621428|ensembl:ENSP00000223129|ensembl:ENSP00000379914|uniprotkb:Q549U6|intact:EBI-1058317 intact:EBI-3893408|uniprotkb:A8MPT9|uniprotkb:Q96ED1|uniprotkb:Q5CZ71|uniprotkb:Q8IXK5|ensembl:ENSP00000380495|ensembl:ENSP00000500171 psi-mi:rfa3_human(display_long)|uniprotkb:Replication factor A protein 3(gene name synonym)|uniprotkb:RPA3(gene name)|psi-mi:RPA3(display_short)|uniprotkb:REPA3(gene name synonym)|uniprotkb:RPA14(gene name synonym) psi-mi:ddx51_human(display_long)|uniprotkb:DDX51(gene name)|psi-mi:DDX51(display_short)|uniprotkb:DEAD box protein 51(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483961|imex:IM-26985-573 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0035861"(site of double-strand break)|ensembl:ENSG00000106399(gene)|go:"GO:0042127"(regulation of cell population proliferation)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013970(Replication factor A protein 3)|mint:P35244|rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|ensembl:ENST00000223129(transcript)|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|ensembl:ENST00000396682(transcript)|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|refseq:NP_002938.1|dip:DIP-24190N refseq:NP_778236.2|ensembl:ENSG00000185163(gene)|ensembl:ENSG00000288503(gene)|ensembl:ENST00000397333(transcript)|ensembl:ENST00000673535(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|mint:Q8N8A6 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:hHO7MxGGHUjz30HXSBZd9cXOq6I9606 rogid:O3uYzRK+gCjUpzIu/5vxVMuBODc9606 rigid:m51TsuiKprkaRBr1V5K/Qd+ZCyY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35244 uniprotkb:Q9BWJ5 intact:EBI-621428|ensembl:ENSP00000223129|ensembl:ENSP00000379914|uniprotkb:Q549U6|intact:EBI-1058317 intact:EBI-2555428|uniprotkb:Q7RTV1|uniprotkb:B2R568|ensembl:ENSP00000356541 psi-mi:rfa3_human(display_long)|uniprotkb:Replication factor A protein 3(gene name synonym)|uniprotkb:RPA3(gene name)|psi-mi:RPA3(display_short)|uniprotkb:REPA3(gene name synonym)|uniprotkb:RPA14(gene name synonym) psi-mi:sf3b5_human(display_long)|uniprotkb:SF3B10(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 10 kDa subunit(gene name synonym)|uniprotkb:SF3B5(gene name)|psi-mi:SF3B5(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483961|imex:IM-26985-573 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0035861"(site of double-strand break)|ensembl:ENSG00000106399(gene)|go:"GO:0042127"(regulation of cell population proliferation)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013970(Replication factor A protein 3)|mint:P35244|rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|ensembl:ENST00000223129(transcript)|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|ensembl:ENST00000396682(transcript)|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|refseq:NP_002938.1|dip:DIP-24190N refseq:NP_112577.1|ensembl:ENSG00000169976(gene)|ensembl:ENST00000367569(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:1990935"(splicing factor binding)|interpro:IPR009846(Splicing factor 3B subunit 5/RDS3 complex subunit 10)|interpro:IPR017089(Splicing factor 3B, subunit 5)|mint:Q9BWJ5|rcsb pdb:5IFE|rcsb pdb:5O9Z|rcsb pdb:5Z56|rcsb pdb:5Z58|rcsb pdb:5ZYA|rcsb pdb:6AH0|rcsb pdb:6EN4|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:6QX9|rcsb pdb:6Y50|rcsb pdb:6Y5Q|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165|rcsb pdb:5Z57 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:hHO7MxGGHUjz30HXSBZd9cXOq6I9606 rogid:wuQBsSytGhSg64IQSmEJXe+26zQ9606 rigid:m51TsuiKprkaRBr1V5K/Qd+ZCyY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35244 uniprotkb:P31949 intact:EBI-621428|ensembl:ENSP00000223129|ensembl:ENSP00000379914|uniprotkb:Q549U6|intact:EBI-1058317 intact:EBI-701862|uniprotkb:Q5VTK0|ensembl:ENSP00000271638 psi-mi:rfa3_human(display_long)|uniprotkb:Replication factor A protein 3(gene name synonym)|uniprotkb:RPA3(gene name)|psi-mi:RPA3(display_short)|uniprotkb:REPA3(gene name synonym)|uniprotkb:RPA14(gene name synonym) psi-mi:s10ab_human(display_long)|uniprotkb:S100 calcium-binding protein A11(gene name synonym)|uniprotkb:Calgizzarin(gene name synonym)|uniprotkb:Metastatic lymph node gene 70 protein(gene name synonym)|uniprotkb:S100A11(gene name)|psi-mi:S100A11(display_short)|uniprotkb:MLN70(gene name synonym)|uniprotkb:S100C(gene name synonym)|uniprotkb:Protein S100-C(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483961|imex:IM-26985-573 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0035861"(site of double-strand break)|ensembl:ENSG00000106399(gene)|go:"GO:0042127"(regulation of cell population proliferation)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013970(Replication factor A protein 3)|mint:P35244|rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|ensembl:ENST00000223129(transcript)|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|ensembl:ENST00000396682(transcript)|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|refseq:NP_002938.1|dip:DIP-24190N refseq:NP_005611.1|ensembl:ENSG00000163191(gene)|ensembl:ENST00000271638(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007165"(signal transduction)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028482|mint:P31949|rcsb pdb:1V4Z|rcsb pdb:1V50|rcsb pdb:2LUC|reactome:R-HSA-6798695 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:hHO7MxGGHUjz30HXSBZd9cXOq6I9606 rogid:BG1iIxIcMpumVbd2yTJwB5gy4VU9606 rigid:m51TsuiKprkaRBr1V5K/Qd+ZCyY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35244 uniprotkb:Q01831 intact:EBI-621428|ensembl:ENSP00000223129|ensembl:ENSP00000379914|uniprotkb:Q549U6|intact:EBI-1058317 intact:EBI-372610|uniprotkb:B4DIP3|uniprotkb:E9PH69|uniprotkb:Q53GT7|uniprotkb:Q96AX0|ensembl:ENSP00000285021|uniprotkb:E9PB96 psi-mi:rfa3_human(display_long)|uniprotkb:Replication factor A protein 3(gene name synonym)|uniprotkb:RPA3(gene name)|psi-mi:RPA3(display_short)|uniprotkb:REPA3(gene name synonym)|uniprotkb:RPA14(gene name synonym) psi-mi:xpc_human(display_long)|uniprotkb:Xeroderma pigmentosum group C-complementing protein(gene name synonym)|uniprotkb:p125(gene name synonym)|uniprotkb:XPC(gene name)|psi-mi:XPC(display_short)|uniprotkb:XPCC(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483961|imex:IM-26985-573 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0035861"(site of double-strand break)|ensembl:ENSG00000106399(gene)|go:"GO:0042127"(regulation of cell population proliferation)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013970(Replication factor A protein 3)|mint:P35244|rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|ensembl:ENST00000223129(transcript)|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|ensembl:ENST00000396682(transcript)|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|refseq:NP_002938.1|dip:DIP-24190N refseq:NP_004619.3|ensembl:ENSG00000154767(gene)|ensembl:ENST00000285021(transcript)|go:"GO:0000109"(nucleotide-excision repair complex)|go:"GO:0000111"(nucleotide-excision repair factor 2 complex)|go:"GO:0000404"(heteroduplex DNA loop binding)|go:"GO:0000405"(bubble DNA binding)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000720"(pyrimidine dimer repair by nucleotide-excision repair)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0010224"(response to UV-B)|go:"GO:0010996"(response to auditory stimulus)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071942"(XPC complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1901990"(regulation of mitotic cell cycle phase transition)|go:"GO:1990731"(UV-damage excision repair, DNA incision)|interpro:IPR004583(DNA repair protein Rad4)|interpro:IPR018026|interpro:IPR018325|interpro:IPR018326|interpro:IPR018327|interpro:IPR018328|interpro:IPR036985|go:"GO:0042493"|interpro:IPR038765|interpro:IPR042488|mint:Q01831|rcsb pdb:2A4J|rcsb pdb:2GGM|rcsb pdb:2OBH|rcsb pdb:2RVB|reactome:R-HSA-3108214|reactome:R-HSA-5696394|reactome:R-HSA-5696395|dip:DIP-31225N - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:hHO7MxGGHUjz30HXSBZd9cXOq6I9606 rogid:PP5XknINbZu7HQiFuOLzUQoaixg9606 rigid:m51TsuiKprkaRBr1V5K/Qd+ZCyY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35244 uniprotkb:P49773 intact:EBI-621428|ensembl:ENSP00000223129|ensembl:ENSP00000379914|uniprotkb:Q549U6|intact:EBI-1058317 intact:EBI-1054330|uniprotkb:Q9H5W8|ensembl:ENSP00000304229 psi-mi:rfa3_human(display_long)|uniprotkb:Replication factor A protein 3(gene name synonym)|uniprotkb:RPA3(gene name)|psi-mi:RPA3(display_short)|uniprotkb:REPA3(gene name synonym)|uniprotkb:RPA14(gene name synonym) psi-mi:hint1_human(display_long)|uniprotkb:Protein kinase C inhibitor 1(gene name synonym)|uniprotkb:Protein kinase C-interacting protein 1(gene name synonym)|uniprotkb:HINT1(gene name)|psi-mi:HINT1(display_short)|uniprotkb:HINT(gene name synonym)|uniprotkb:PKCI1(gene name synonym)|uniprotkb:PRKCNH1(gene name synonym)|uniprotkb:Desumoylating isopeptidase HINT1(gene name synonym)|uniprotkb:Histidine triad nucleotide-binding protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483961|imex:IM-26985-573 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0035861"(site of double-strand break)|ensembl:ENSG00000106399(gene)|go:"GO:0042127"(regulation of cell population proliferation)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013970(Replication factor A protein 3)|mint:P35244|rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|ensembl:ENST00000223129(transcript)|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|ensembl:ENST00000396682(transcript)|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|refseq:NP_002938.1|dip:DIP-24190N refseq:NP_005331.1|go:"GO:0016787"(hydrolase activity)|go:"GO:0043530"(adenosine 5'-monophosphoramidase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|interpro:IPR001310("Histidine triad (HIT) protein")|interpro:IPR011146(Histidine triad-like motif)|interpro:IPR019808|interpro:IPR036265|mint:P49773|rcsb pdb:1AV5|rcsb pdb:1KPA|rcsb pdb:1KPB|rcsb pdb:1KPC|rcsb pdb:1KPE|rcsb pdb:1KPF|rcsb pdb:3TW2|ensembl:ENSG00000169567(gene)|ensembl:ENST00000304043(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000166"(nucleotide binding)|rcsb pdb:4EQE|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|rcsb pdb:4EQG|go:"GO:0005654"(nucleoplasm)|rcsb pdb:4EQH|rcsb pdb:4ZKL|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007165"(signal transduction)|go:"GO:0009154"(purine ribonucleotide catabolic process)|rcsb pdb:4ZKV|rcsb pdb:5ED3|rcsb pdb:5ED6|rcsb pdb:5EMT|rcsb pdb:5I2E|rcsb pdb:5I2F|rcsb pdb:5IPB|rcsb pdb:5IPC|rcsb pdb:5IPD|rcsb pdb:5IPE|rcsb pdb:5KLY|rcsb pdb:5KLZ|rcsb pdb:5KM0|rcsb pdb:5KM1|rcsb pdb:5KM2|rcsb pdb:5KM3|rcsb pdb:5KM4|rcsb pdb:5KM6|rcsb pdb:5KMA|rcsb pdb:5KMB|rcsb pdb:5KMC|rcsb pdb:5O8I|rcsb pdb:5WA8|rcsb pdb:5WA9|rcsb pdb:5WAA|rcsb pdb:6B42|rcsb pdb:6G9Z|rcsb pdb:6J53|rcsb pdb:6J58|rcsb pdb:6J5S|rcsb pdb:6J5Z|rcsb pdb:6J64|rcsb pdb:6J65|rcsb pdb:6N3V|rcsb pdb:6N3W|rcsb pdb:6N3X|rcsb pdb:6N3Y|rcsb pdb:6YQM - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:hHO7MxGGHUjz30HXSBZd9cXOq6I9606 rogid:vXotU/cqS8hSHeBmCk30zSQ9k/E9606 rigid:m51TsuiKprkaRBr1V5K/Qd+ZCyY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35244 uniprotkb:P39019 intact:EBI-621428|ensembl:ENSP00000223129|ensembl:ENSP00000379914|uniprotkb:Q549U6|intact:EBI-1058317 intact:EBI-354451|ensembl:ENSP00000469228|ensembl:ENSP00000470004|ensembl:ENSP00000470972 psi-mi:rfa3_human(display_long)|uniprotkb:Replication factor A protein 3(gene name synonym)|uniprotkb:RPA3(gene name)|psi-mi:RPA3(display_short)|uniprotkb:REPA3(gene name synonym)|uniprotkb:RPA14(gene name synonym) psi-mi:rs19_human(display_long)|uniprotkb:RPS19(gene name)|psi-mi:RPS19(display_short)|uniprotkb:Small ribosomal subunit protein eS19(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483961|imex:IM-26985-573 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0035861"(site of double-strand break)|ensembl:ENSG00000106399(gene)|go:"GO:0042127"(regulation of cell population proliferation)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013970(Replication factor A protein 3)|mint:P35244|rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|ensembl:ENST00000223129(transcript)|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|ensembl:ENST00000396682(transcript)|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|refseq:NP_002938.1|dip:DIP-24190N refseq:NP_001013.1|ensembl:ENSG00000105372(gene)|ensembl:ENST00000593863(transcript)|ensembl:ENST00000598742(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003723"(RNA binding)|ensembl:ENST00000600467(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0007000"(nucleolus organization)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0060265"(positive regulation of respiratory burst involved in inflammatory response)|go:"GO:0060266"(negative regulation of respiratory burst involved in inflammatory response)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001266(Ribosomal protein S19e)|interpro:IPR018277|interpro:IPR036388|interpro:IPR036390|mint:P39019|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001308412.1|refseq:NP_001308413.1 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:hHO7MxGGHUjz30HXSBZd9cXOq6I9606 rogid:3YqdJJJG+2nqoBf3PLu1fs7pVkY9606 rigid:m51TsuiKprkaRBr1V5K/Qd+ZCyY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35244 uniprotkb:P54727 intact:EBI-621428|ensembl:ENSP00000223129|ensembl:ENSP00000379914|uniprotkb:Q549U6|intact:EBI-1058317 intact:EBI-954531|uniprotkb:Q8WUB0|uniprotkb:B3KWK8|ensembl:ENSP00000350708|uniprotkb:G5E9P0|uniprotkb:Q7Z5K8 psi-mi:rfa3_human(display_long)|uniprotkb:Replication factor A protein 3(gene name synonym)|uniprotkb:RPA3(gene name)|psi-mi:RPA3(display_short)|uniprotkb:REPA3(gene name synonym)|uniprotkb:RPA14(gene name synonym) psi-mi:rd23b_human(display_long)|uniprotkb:XP-C repair-complementing complex 58 kDa protein(gene name synonym)|uniprotkb:RAD23B(gene name)|psi-mi:RAD23B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483961|imex:IM-26985-573 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0035861"(site of double-strand break)|ensembl:ENSG00000106399(gene)|go:"GO:0042127"(regulation of cell population proliferation)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013970(Replication factor A protein 3)|mint:P35244|rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|ensembl:ENST00000223129(transcript)|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|ensembl:ENST00000396682(transcript)|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|refseq:NP_002938.1|dip:DIP-24190N refseq:NP_002865.1|refseq:NP_001231653.1|ensembl:ENSG00000119318(gene)|ensembl:ENST00000358015(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0000715"(nucleotide-excision repair, DNA damage recognition)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0048568"(embryonic organ development)|go:"GO:0070628"(proteasome binding)|go:"GO:0071942"(XPC complex)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000626(Ubiquitin)|interpro:IPR004806(UV excision repair protein Rad23)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR009060(UBA-like)|interpro:IPR015360(XPC-binding domain)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR036353|interpro:IPR041811|mint:P54727|rcsb pdb:1P1A|rcsb pdb:1PVE|rcsb pdb:1UEL|reactome:R-HSA-532668|reactome:R-HSA-5689877|reactome:R-HSA-5696394|reactome:R-HSA-5696395|interpro:IPR029071|dip:DIP-39944N - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:hHO7MxGGHUjz30HXSBZd9cXOq6I9606 rogid:msyh4+G2TzDW+xgGjixPKWWrjRE9606 rigid:m51TsuiKprkaRBr1V5K/Qd+ZCyY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35244 uniprotkb:P13010 intact:EBI-621428|ensembl:ENSP00000223129|ensembl:ENSP00000379914|uniprotkb:Q549U6|intact:EBI-1058317 intact:EBI-357997|uniprotkb:A8K3X5|uniprotkb:Q0Z7V0|uniprotkb:Q53HH7|uniprotkb:Q7M4N0|uniprotkb:Q4VBQ5|uniprotkb:Q9UCQ0|uniprotkb:Q9UCQ1|ensembl:ENSP00000375977|ensembl:ENSP00000375978 psi-mi:rfa3_human(display_long)|uniprotkb:Replication factor A protein 3(gene name synonym)|uniprotkb:RPA3(gene name)|psi-mi:RPA3(display_short)|uniprotkb:REPA3(gene name synonym)|uniprotkb:RPA14(gene name synonym) psi-mi:xrcc5_human(display_long)|uniprotkb:XRCC5(gene name)|psi-mi:XRCC5(display_short)|uniprotkb:G22P2(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 80 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p86(gene name synonym)|uniprotkb:86 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Ku86(gene name synonym)|uniprotkb:Ku80(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 85 kDa subunit(gene name synonym)|uniprotkb:Nuclear factor IV(gene name synonym)|uniprotkb:DNA repair protein XRCC5(gene name synonym)|uniprotkb:"X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)"(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483961|imex:IM-26985-573 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0035861"(site of double-strand break)|ensembl:ENSG00000106399(gene)|go:"GO:0042127"(regulation of cell population proliferation)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013970(Replication factor A protein 3)|mint:P35244|rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|ensembl:ENST00000223129(transcript)|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|ensembl:ENST00000396682(transcript)|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|refseq:NP_002938.1|dip:DIP-24190N refseq:NP_066964.1|ensembl:ENST00000392132(transcript)|ensembl:ENSG00000079246(gene)|dip:DIP-31379N|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045027"(DNA end binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0090734"(site of DNA damage)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|ensembl:ENST00000392133(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008047"(enzyme activator activity)|go:"GO:1904430"(negative regulation of t-circle formation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR014893(Ku, C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR024193|interpro:IPR036465|interpro:IPR036494|mint:P13010|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1Q2Z|rcsb pdb:1RW2|rcsb pdb:3RZ9|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZH6|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7AXZ|rcsb pdb:7K0Y|rcsb pdb:7K17|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695 - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:hHO7MxGGHUjz30HXSBZd9cXOq6I9606 rogid:ZPJCWdA2YqOqXgfSRfDQCoEsyoA9606 rigid:m51TsuiKprkaRBr1V5K/Qd+ZCyY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35244 uniprotkb:P12956 intact:EBI-621428|ensembl:ENSP00000223129|ensembl:ENSP00000379914|uniprotkb:Q549U6|intact:EBI-1058317 intact:EBI-353208|ensembl:ENSP00000352257|ensembl:ENSP00000353192|ensembl:ENSP00000384257|intact:EBI-2843064|uniprotkb:Q6FG89|uniprotkb:Q9UCQ2|uniprotkb:Q9UCQ3|intact:EBI-8456785|intact:MINT-8429298|uniprotkb:B1AHC8 psi-mi:rfa3_human(display_long)|uniprotkb:Replication factor A protein 3(gene name synonym)|uniprotkb:RPA3(gene name)|psi-mi:RPA3(display_short)|uniprotkb:REPA3(gene name synonym)|uniprotkb:RPA14(gene name synonym) psi-mi:xrcc6_human(display_long)|uniprotkb:XRCC6(gene name)|psi-mi:XRCC6(display_short)|uniprotkb:G22P1(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 70 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p70(gene name synonym)|uniprotkb:70 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 75 kDa subunit(gene name synonym)|uniprotkb:DNA repair protein XRCC6(gene name synonym)|uniprotkb:X-ray repair complementing defective repair in Chinese hamster cells 6(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 1(gene name synonym)|uniprotkb:5'-deoxyribose-5-phosphate lyase Ku70(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483961|imex:IM-26985-573 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0035861"(site of double-strand break)|ensembl:ENSG00000106399(gene)|go:"GO:0042127"(regulation of cell population proliferation)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013970(Replication factor A protein 3)|mint:P35244|rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|ensembl:ENST00000223129(transcript)|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|ensembl:ENST00000396682(transcript)|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|refseq:NP_002938.1|dip:DIP-24190N go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR006165(DNA helicase, ATP-dependent, Ku70 subunit)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR027388|interpro:IPR036361|interpro:IPR036465|mint:P12956|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1JJR|rcsb pdb:3RZX|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZHA|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|rcsb pdb:6ZHE|rcsb pdb:7AXZ|interpro:IPR003034(DNA-binding SAP)|rcsb pdb:7K0Y|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000196419(gene)|go:"GO:0005829"(cytosol)|go:"GO:0006266"(DNA ligation)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|ensembl:ENST00000359308(transcript)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|ensembl:ENST00000360079(transcript)|ensembl:ENST00000405878(transcript)|go:"GO:0016020"(membrane)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|refseq:NP_001460.1|refseq:NP_001275906.1|refseq:NP_001275905.1|dip:DIP-24188N - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:hHO7MxGGHUjz30HXSBZd9cXOq6I9606 rogid:45wj3HmNJ4dfVgw0zc2r3AUZ0Dw9606 rigid:m51TsuiKprkaRBr1V5K/Qd+ZCyY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35244 uniprotkb:Q04837 intact:EBI-621428|ensembl:ENSP00000223129|ensembl:ENSP00000379914|uniprotkb:Q549U6|intact:EBI-1058317 intact:EBI-353460|ensembl:ENSP00000265304|ensembl:ENSP00000419388|ensembl:ENSP00000419541|ensembl:ENSP00000419665|ensembl:ENSP00000420485|ensembl:ENSP00000458815|ensembl:ENSP00000459208|ensembl:ENSP00000459367|ensembl:ENSP00000460028|ensembl:ENSP00000461884|ensembl:ENSP00000480488 psi-mi:rfa3_human(display_long)|uniprotkb:Replication factor A protein 3(gene name synonym)|uniprotkb:RPA3(gene name)|psi-mi:RPA3(display_short)|uniprotkb:REPA3(gene name synonym)|uniprotkb:RPA14(gene name synonym) psi-mi:ssbp_human(display_long)|uniprotkb:SSBP1(gene name)|psi-mi:SSBP1(display_short)|uniprotkb:SSBP(gene name synonym)|uniprotkb:PWP1-interacting protein 17(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483961|imex:IM-26985-573 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0035861"(site of double-strand break)|ensembl:ENSG00000106399(gene)|go:"GO:0042127"(regulation of cell population proliferation)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013970(Replication factor A protein 3)|mint:P35244|rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|ensembl:ENST00000223129(transcript)|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|ensembl:ENST00000396682(transcript)|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|refseq:NP_002938.1|dip:DIP-24190N refseq:NP_003134.1|refseq:NP_001243439.1|refseq:NP_001243440.1|refseq:NP_001243441.1|refseq:NP_001243442.1|ensembl:ENSG00000106028(gene)|ensembl:ENSG00000262771(gene)|ensembl:ENST00000265304(transcript)|ensembl:ENST00000465582(transcript)|ensembl:ENST00000481508(transcript)|ensembl:ENST00000484178(transcript)|ensembl:ENST00000498107(transcript)|ensembl:ENST00000570667(transcript)|ensembl:ENST00000571430(transcript)|ensembl:ENST00000574199(transcript)|ensembl:ENST00000575059(transcript)|ensembl:ENST00000576834(transcript)|ensembl:ENST00000612337(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0009295"(nucleoid)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0051096"(positive regulation of helicase activity)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|go:"GO:1905776"(positive regulation of DNA helicase activity)|interpro:IPR000424(Primosome PriB/single-strand DNA-binding)|interpro:IPR011344(Single-strand DNA-binding)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|mint:Q04837|rcsb pdb:1S3O|rcsb pdb:2DUD|rcsb pdb:3ULL|rcsb pdb:6RUP|reactome:R-HSA-2151201 - - comment:"author score: 31" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:hHO7MxGGHUjz30HXSBZd9cXOq6I9606 rogid:W/7kbgBRtYcjJfr2XbA1OK9BOS49606 rigid:m51TsuiKprkaRBr1V5K/Qd+ZCyY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35244 uniprotkb:Q14527 intact:EBI-621428|ensembl:ENSP00000223129|ensembl:ENSP00000379914|uniprotkb:Q549U6|intact:EBI-1058317 intact:EBI-1045161|uniprotkb:Q14536|uniprotkb:Q16051|uniprotkb:Q7KYJ6|uniprotkb:Q86YA5|uniprotkb:Q92652|uniprotkb:Q96KM9|uniprotkb:D3DNH3|ensembl:ENSP00000308944|ensembl:ENSP00000376644|ensembl:ENSP00000420429 psi-mi:rfa3_human(display_long)|uniprotkb:Replication factor A protein 3(gene name synonym)|uniprotkb:RPA3(gene name)|psi-mi:RPA3(display_short)|uniprotkb:REPA3(gene name synonym)|uniprotkb:RPA14(gene name synonym) psi-mi:hltf_human(display_long)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 3(gene name synonym)|uniprotkb:DNA-binding protein/plasminogen activator inhibitor 1 regulator(gene name synonym)|uniprotkb:HIP116(gene name synonym)|uniprotkb:RING finger protein 80(gene name synonym)|uniprotkb:HLTF(gene name)|psi-mi:HLTF(display_short)|uniprotkb:HIP116A(gene name synonym)|uniprotkb:RNF80(gene name synonym)|uniprotkb:SNF2L3(gene name synonym)|uniprotkb:ZBU1(gene name synonym)|uniprotkb:SMARCA3(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase HLTF(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483961|imex:IM-26985-573 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0035861"(site of double-strand break)|ensembl:ENSG00000106399(gene)|go:"GO:0042127"(regulation of cell population proliferation)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013970(Replication factor A protein 3)|mint:P35244|rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|ensembl:ENST00000223129(transcript)|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|ensembl:ENST00000396682(transcript)|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|refseq:NP_002938.1|dip:DIP-24190N refseq:NP_001305863.1|refseq:NP_001305864.1|refseq:NP_003062.2|refseq:NP_620636.1|refseq:XP_016862568.1|dip:DIP-29828N|ensembl:ENSG00000071794(gene)|ensembl:ENST00000310053(transcript)|ensembl:ENST00000392912(transcript)|ensembl:ENST00000494055(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016818"(hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070615"|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014905(HIRAN)|interpro:IPR017907|interpro:IPR027417|interpro:IPR038718|mint:Q14527|rcsb pdb:2MZN|rcsb pdb:4HRE|rcsb pdb:4HRH|rcsb pdb:4S0N|rcsb pdb:4XZF|rcsb pdb:4XZG|rcsb pdb:5BNH|rcsb pdb:5K5F|rcsb pdb:6KCS|reactome:R-HSA-8866654 - - comment:"author score: 34" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:hHO7MxGGHUjz30HXSBZd9cXOq6I9606 rogid:ozxGwYPSrDJ+Fg3F64VfE0Bc0wM9606 rigid:m51TsuiKprkaRBr1V5K/Qd+ZCyY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35244 uniprotkb:P40937 intact:EBI-621428|ensembl:ENSP00000223129|ensembl:ENSP00000379914|uniprotkb:Q549U6|intact:EBI-1058317 intact:EBI-712376|ensembl:ENSP00000408295|uniprotkb:A8MZ62|uniprotkb:B3KSX8 psi-mi:rfa3_human(display_long)|uniprotkb:Replication factor A protein 3(gene name synonym)|uniprotkb:RPA3(gene name)|psi-mi:RPA3(display_short)|uniprotkb:REPA3(gene name synonym)|uniprotkb:RPA14(gene name synonym) psi-mi:rfc5_human(display_long)|uniprotkb:Activator 1 subunit 5(gene name synonym)|uniprotkb:Replication factor C 36 kDa subunit(gene name synonym)|uniprotkb:Activator 1 36 kDa subunit(gene name synonym)|uniprotkb:RFC5(gene name)|psi-mi:RFC5(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25483961|imex:IM-26985-573 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0035861"(site of double-strand break)|ensembl:ENSG00000106399(gene)|go:"GO:0042127"(regulation of cell population proliferation)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013970(Replication factor A protein 3)|mint:P35244|rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|ensembl:ENST00000223129(transcript)|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|ensembl:ENST00000396682(transcript)|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|refseq:NP_002938.1|dip:DIP-24190N refseq:NP_031396.1|refseq:NP_853556.2|ensembl:ENSG00000111445(gene)|ensembl:ENST00000454402(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005663"(DNA replication factor C complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0019899"(enzyme binding)|go:"GO:0031390"(Ctf18 RFC-like complex)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:1900264"(positive regulation of DNA-directed DNA polymerase activity)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR003959(AAA ATPase, core)|interpro:IPR008921(DNA polymerase III clamp loader subunit, C-terminal)|interpro:IPR013748(Replication factor C)|interpro:IPR027417|mint:P40937|rcsb pdb:1LFS|rcsb pdb:6VVO|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174411|reactome:R-HSA-176187|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6804756|reactome:R-HSA-69091|reactome:R-HSA-69473|refseq:XP_011536945.1|refseq:XP_011536947.1|refseq:NP_001123584.1|refseq:NP_001123585.1|dip:DIP-36433N - - comment:"author score: 37" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:hHO7MxGGHUjz30HXSBZd9cXOq6I9606 rogid:F7oadHDk6fkhHn+3rDF9K2JHSl49606 rigid:m51TsuiKprkaRBr1V5K/Qd+ZCyY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96F10 uniprotkb:Q8N488 intact:EBI-748746|ensembl:ENSP00000269298 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 psi-mi:sat2_human(display_long)|uniprotkb:"Spermidine/spermine N(1)-acetyltransferase 2"(gene name synonym)|uniprotkb:SAT2(gene name)|psi-mi:SAT2(display_short)|uniprotkb:SSAT2(gene name synonym)|uniprotkb:Diamine acetyltransferase 2(gene name synonym) psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484261|imex:IM-26985-351 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_597998.1|refseq:NP_001307775.1|refseq:NP_001307776.1|ensembl:ENSG00000141504(gene)|ensembl:ENST00000269298(transcript)|go:"GO:0004145"(diamine N-acetyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0019809"(spermidine binding)|go:"GO:0032918"(spermidine acetylation)|go:"GO:0032920"(putrescine acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0046204"(nor-spermidine metabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR032959|mint:Q96F10|rcsb pdb:2BEI|rcsb pdb:2Q4V|go:"GO:0032919"(spermine acetylation) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity) - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:za90gPs85bZdWO7RYTGA9V7nazY9606 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rigid:ydHK5ltXmG/5b+5gnfxEEUGF8uI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96F10 uniprotkb:P16403 intact:EBI-748746|ensembl:ENSP00000269298 intact:EBI-358372|ensembl:ENSP00000339566|uniprotkb:A8K4I2 psi-mi:sat2_human(display_long)|uniprotkb:"Spermidine/spermine N(1)-acetyltransferase 2"(gene name synonym)|uniprotkb:SAT2(gene name)|psi-mi:SAT2(display_short)|uniprotkb:SSAT2(gene name synonym)|uniprotkb:Diamine acetyltransferase 2(gene name synonym) psi-mi:h12_human(display_long)|uniprotkb:H1-2(gene name)|psi-mi:H1-2(display_short)|uniprotkb:H1F2(gene name synonym)|uniprotkb:HIST1H1C(gene name synonym)|uniprotkb:Histone H1c(gene name synonym)|uniprotkb:Histone H1d(gene name synonym)|uniprotkb:Histone H1s-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484261|imex:IM-26985-351 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_597998.1|refseq:NP_001307775.1|refseq:NP_001307776.1|ensembl:ENSG00000141504(gene)|ensembl:ENST00000269298(transcript)|go:"GO:0004145"(diamine N-acetyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0019809"(spermidine binding)|go:"GO:0032918"(spermidine acetylation)|go:"GO:0032920"(putrescine acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0046204"(nor-spermidine metabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR032959|mint:Q96F10|rcsb pdb:2BEI|rcsb pdb:2Q4V|go:"GO:0032919"(spermine acetylation) refseq:NP_005310.1|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P16403|reactome:R-HSA-140342|reactome:R-HSA-2559584|ensembl:ENSG00000187837(gene)|ensembl:ENST00000343677(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|dip:DIP-36359N - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:za90gPs85bZdWO7RYTGA9V7nazY9606 rogid:eRT5bTyBJUg6nRANMRYZekT4N+g9606 rigid:ydHK5ltXmG/5b+5gnfxEEUGF8uI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96F10 uniprotkb:P02814 intact:EBI-748746|ensembl:ENSP00000269298 intact:EBI-738612|uniprotkb:Q9UBN0|uniprotkb:Q9UCT0|uniprotkb:B7ZMG7|ensembl:ENSP00000302400|ensembl:ENSP00000423138 psi-mi:sat2_human(display_long)|uniprotkb:"Spermidine/spermine N(1)-acetyltransferase 2"(gene name synonym)|uniprotkb:SAT2(gene name)|psi-mi:SAT2(display_short)|uniprotkb:SSAT2(gene name synonym)|uniprotkb:Diamine acetyltransferase 2(gene name synonym) psi-mi:smr3b_human(display_long)|uniprotkb:SMR3B(gene name)|psi-mi:SMR3B(display_short)|uniprotkb:PBII(gene name synonym)|uniprotkb:PRL3(gene name synonym)|uniprotkb:Proline-rich protein 3(gene name synonym)|uniprotkb:Proline-rich peptide P-B(gene name synonym)|uniprotkb:PROL3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484261|imex:IM-26985-351 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_597998.1|refseq:NP_001307775.1|refseq:NP_001307776.1|ensembl:ENSG00000141504(gene)|ensembl:ENST00000269298(transcript)|go:"GO:0004145"(diamine N-acetyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0019809"(spermidine binding)|go:"GO:0032918"(spermidine acetylation)|go:"GO:0032920"(putrescine acetylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0046204"(nor-spermidine metabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR032959|mint:Q96F10|rcsb pdb:2BEI|rcsb pdb:2Q4V|go:"GO:0032919"(spermine acetylation) refseq:NP_006676.1|ensembl:ENSG00000171201(gene)|ensembl:ENST00000304915(transcript)|ensembl:ENST00000504825(transcript)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0070062"(extracellular exosome)|interpro:IPR026288|mint:P02814 - - comment:"author score: 54" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:za90gPs85bZdWO7RYTGA9V7nazY9606 rogid:WJ7Ag6lcBGK16pBo7LaEWJ1hydg9606 rigid:ydHK5ltXmG/5b+5gnfxEEUGF8uI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35030 uniprotkb:P21673 intact:EBI-1221209|uniprotkb:Q5VXV0|intact:EBI-2825937|uniprotkb:A8CED3|uniprotkb:F8W7P3|uniprotkb:Q6ISJ4|uniprotkb:P15951|uniprotkb:Q15665|uniprotkb:Q9UQV3|uniprotkb:A9Z1Y4|uniprotkb:E7ES07|uniprotkb:A8CED1 intact:EBI-711613|ensembl:ENSP00000368572|intact:EBI-10178867|uniprotkb:Q6ICU9 psi-mi:try3_human(display_long)|uniprotkb:PRSS3(gene name)|psi-mi:PRSS3(display_short)|uniprotkb:PRSS4(gene name synonym)|uniprotkb:TRY3(gene name synonym)|uniprotkb:TRY4(gene name synonym)|uniprotkb:Trypsin III(gene name synonym)|uniprotkb:Brain trypsinogen(gene name synonym)|uniprotkb:Mesotrypsinogen(gene name synonym)|uniprotkb:Trypsin IV(gene name synonym)|uniprotkb:Serine protease 3(gene name synonym)|uniprotkb:Serine protease 4(gene name synonym)|uniprotkb:Mesotrypsin(gene name synonym) psi-mi:sat1_human(display_long)|uniprotkb:SAT1(gene name)|psi-mi:SAT1(display_short)|uniprotkb:"Spermidine/spermine N(1)-acetyltransferase 1"(gene name synonym)|uniprotkb:Putrescine acetyltransferase(gene name synonym)|uniprotkb:Polyamine N-acetyltransferase 1(gene name synonym)|uniprotkb:SAT(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25484252|imex:IM-26985-275 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002762.2|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|refseq:NP_001184026.2|refseq:NP_031369.2|refseq:NP_001184027.1|mint:P35030|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0007586"(digestion)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0031638"(zymogen activation)|go:"GO:0043542"(endothelial cell migration)|go:"GO:1904724"(tertiary granule lumen)|rcsb pdb:1H4W|rcsb pdb:2R9P|rcsb pdb:3L33|rcsb pdb:3L3T|rcsb pdb:3P92|rcsb pdb:3P95|rcsb pdb:4DG4|rcsb pdb:4U30|rcsb pdb:4U32|rcsb pdb:5C67|rcsb pdb:5JBT|rcsb pdb:5TP0|rcsb pdb:6BX8|rcsb pdb:6GFI|reactome:R-HSA-1462054|reactome:R-HSA-196741|reactome:R-HSA-6798695|reactome:R-HSA-6803157|interpro:IPR043504 ensembl:ENSG00000130066(gene)|ensembl:ENST00000379270(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0004145"(diamine N-acetyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0006596"(polyamine biosynthetic process)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0009447"(putrescine catabolic process)|go:"GO:0019809"(spermidine binding)|go:"GO:0032918"(spermidine acetylation)|go:"GO:0042802"(identical protein binding)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR032957|mint:P21673|rcsb pdb:2B3U|rcsb pdb:2B3V|rcsb pdb:2B4B|rcsb pdb:2B4D|rcsb pdb:2B58|rcsb pdb:2B5G|rcsb pdb:2F5I|rcsb pdb:2FXF|rcsb pdb:2G3T|rcsb pdb:2JEV|reactome:R-HSA-351200|refseq:NP_002961.1|dip:DIP-36801N - comment:"author score: 11" - figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:AEfz7orXeNoasizB5N76AkF4WMk9606 rogid:xuCACF5E/GV3eKfMqdhnXImFfmk9606 rigid:MIUHGcnaZf/P0xN5rWmlG37fVLI false - tandem tag:n-n - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:Q8NHM5 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-3955564|uniprotkb:Q1RLM7|uniprotkb:Q8NCI2|uniprotkb:Q96HC7|uniprotkb:Q96SL0|uniprotkb:Q96T03|uniprotkb:Q9NS96|uniprotkb:Q9UF75|ensembl:ENSP00000366271|uniprotkb:A8MRS1 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:kdm2b_human(display_long)|uniprotkb:KDM2B(gene name)|psi-mi:KDM2B(display_short)|uniprotkb:CXXC2(gene name synonym)|uniprotkb:FBL10(gene name synonym)|uniprotkb:FBXL10(gene name synonym)|uniprotkb:JHDM1B(gene name synonym)|uniprotkb:PCCX2(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 2(gene name synonym)|uniprotkb:F-box and leucine-rich repeat protein 10(gene name synonym)|uniprotkb:F-box protein FBL10(gene name synonym)|uniprotkb:F-box/LRR-repeat protein 10(gene name synonym)|uniprotkb:JmjC domain-containing histone demethylation protein 1B(gene name synonym)|uniprotkb:Jumonji domain-containing EMSY-interactor methyltransferase motif protein(gene name synonym)|uniprotkb:Protein-containing CXXC domain 2(gene name synonym)|uniprotkb:[Histone-H3]-lysine-36 demethylase 1B(gene name synonym)|uniprotkb:NDY1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484183|imex:IM-26985-205 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity) go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|ensembl:ENST00000377071(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019843"(rRNA binding)|go:"GO:0021555"(midbrain-hindbrain boundary morphogenesis)|go:"GO:0021592"(fourth ventricle development)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021678"(third ventricle development)|go:"GO:0021993"(initiation of neural tube closure)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030900"(forebrain development)|go:"GO:0030901"(midbrain development)|go:"GO:0030902"(hindbrain development)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0048596"(embryonic camera-type eye morphogenesis)|go:"GO:0051864"(histone H3-methyl-lysine-36 demethylase activity)|go:"GO:0070544"(histone H3-K36 demethylation)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:2000178"(negative regulation of neural precursor cell proliferation)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR032675|interpro:IPR041070|interpro:IPR041667|mint:Q8NHM5|rcsb pdb:4O64|rcsb pdb:5JH5|rcsb pdb:6BVA|reactome:R-HSA-3214842|refseq:NP_115979.3|ensembl:ENSG00000089094(gene)|refseq:NP_001005366.1 - - comment:"author score: 55" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:tnMbfP2oxwaaDyHHAigNt5hx4hM9606 rigid:6R3X3L39NBQo+KQYhJyqQV17Yc4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:Q8NDL9 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-7962937|uniprotkb:Q9H8P8|uniprotkb:Q9H6V0|uniprotkb:Q96IK8|uniprotkb:B7Z7I7|uniprotkb:Q53SZ0|uniprotkb:Q53SW0|uniprotkb:B7WPG9|intact:MINT-4717805|uniprotkb:A2VDI7|uniprotkb:D6W548|ensembl:ENSP00000353249 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:cbpc5_human(display_long)|uniprotkb:Protein deglutamylase CCP5(gene name synonym)|uniprotkb:AGBL5(gene name)|psi-mi:AGBL5(display_short)|uniprotkb:CCP5(gene name synonym)|uniprotkb:ATP/GTP-binding protein-like 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484183|imex:IM-26985-205 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity) refseq:XP_011531313.1|refseq:XP_011531314.1|refseq:XP_011531315.1|refseq:NP_001030584.1|refseq:NP_068603.4|ensembl:ENSG00000084693(gene)|ensembl:ENST00000360131(transcript)|go:"GO:0004181"(metallocarboxypeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0030496"(midbody)|go:"GO:0035608"(protein deglutamylation)|go:"GO:0035611"(protein branching point deglutamylation)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051607"(defense response to virus)|go:"GO:0072686"(mitotic spindle)|interpro:IPR000834(Peptidase M14, carboxypeptidase A)|interpro:IPR034286|interpro:IPR040626|mint:Q8NDL9|reactome:R-HSA-8955332 - - comment:mint|comment:"author score: 28" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:ymXCvYKmtqHnaafXZoynEJhVt9M9606 rigid:6R3X3L39NBQo+KQYhJyqQV17Yc4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:Q969R5 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484183|imex:IM-26985-205 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rigid:6R3X3L39NBQo+KQYhJyqQV17Yc4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:P67870 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-348169|ensembl:ENSP00000365025|ensembl:ENSP00000365026|ensembl:ENSP00000365042|ensembl:ENSP00000372919|ensembl:ENSP00000372925|ensembl:ENSP00000382980|ensembl:ENSP00000390900|ensembl:ENSP00000391038|ensembl:ENSP00000393756|ensembl:ENSP00000394855|ensembl:ENSP00000395275|ensembl:ENSP00000400188|ensembl:ENSP00000407018|ensembl:ENSP00000407379|ensembl:ENSP00000409510|ensembl:ENSP00000410802|ensembl:ENSP00000411322|ensembl:ENSP00000412520|ensembl:ENSP00000413469|ensembl:ENSP00000415237|ensembl:ENSP00000415303|uniprotkb:P07312|uniprotkb:P13862|uniprotkb:Q4VX47|intact:EBI-3866975|uniprotkb:B0UXA9 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:csk2b_human(display_long)|uniprotkb:Phosvitin(gene name synonym)|uniprotkb:Protein G5a(gene name synonym)|uniprotkb:CSNK2B(gene name)|psi-mi:CSNK2B(display_short)|uniprotkb:CK2N(gene name synonym)|uniprotkb:G5A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484183|imex:IM-26985-205 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity) ensembl:ENSG00000204435(gene)|ensembl:ENSG00000230700(gene)|ensembl:ENSG00000206406(gene)|ensembl:ENSG00000232960(gene)|ensembl:ENSG00000224398(gene)|ensembl:ENSG00000224774(gene)|ensembl:ENSG00000228875(gene)|ensembl:ENST00000375882(transcript)|ensembl:ENST00000383427(transcript)|ensembl:ENST00000383433(transcript)|ensembl:ENST00000400110(transcript)|ensembl:ENST00000412802(transcript)|ensembl:ENST00000418230(transcript)|ensembl:ENST00000422567(transcript)|ensembl:ENST00000429633(transcript)|ensembl:ENST00000431476(transcript)|ensembl:ENST00000436169(transcript)|ensembl:ENST00000443673(transcript)|ensembl:ENST00000448596(transcript)|ensembl:ENST00000451917(transcript)|ensembl:ENST00000452985(transcript)|ensembl:ENST00000453234(transcript)|ensembl:ENST00000454382(transcript)|ensembl:ENST00000454511(transcript)|ensembl:ENST00000455161(transcript)|ensembl:ENST00000458330(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0007165"(signal transduction)|ensembl:ENST00000375865(transcript)|ensembl:ENST00000375866(transcript)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016363"(nuclear matrix)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032927"(positive regulation of activin receptor signaling pathway)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0033574"(response to testosterone)|go:"GO:0034622"|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR035991|mint:P67870|rcsb pdb:1DS5|rcsb pdb:1JWH|go:"GO:0008134"(transcription factor binding)|rcsb pdb:1QF8|rcsb pdb:3EED|rcsb pdb:4DGL|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6798695|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:6Q38|refseq:NP_001311.3|refseq:NP_001269314.1|dip:DIP-131N - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:ZTHJjCqHg2dE7B+WoSU28VSMuPg9606 rigid:6R3X3L39NBQo+KQYhJyqQV17Yc4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:P68400 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-347804|ensembl:ENSP00000217244|ensembl:ENSP00000383076|ensembl:ENSP00000495248|ensembl:ENSP00000495422|ensembl:ENSP00000495902|ensembl:ENSP00000495912|ensembl:ENSP00000495998|ensembl:ENSP00000496569|uniprotkb:P19138|uniprotkb:P20426|uniprotkb:Q14013|uniprotkb:Q5U065|uniprotkb:D3DVV8|uniprotkb:B4DYS6 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:csk21_human(display_long)|uniprotkb:CSNK2A1(gene name)|psi-mi:CSNK2A1(display_short)|uniprotkb:CK2A1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484183|imex:IM-26985-205 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity) rcsb pdb:6TLS|rcsb pdb:6TLU|rcsb pdb:6TLV|rcsb pdb:6TLW|rcsb pdb:6YPG|rcsb pdb:6YPH|rcsb pdb:6YPJ|rcsb pdb:6YPK|rcsb pdb:6YPN|rcsb pdb:6YUL|rcsb pdb:6YUM|rcsb pdb:6YZH|rcsb pdb:6Z19|rcsb pdb:6Z83|rcsb pdb:6Z84|rcsb pdb:7A49|rcsb pdb:6TLR|rcsb pdb:7A4B|rcsb pdb:7A4C|rcsb pdb:7B8H|rcsb pdb:3PE2|rcsb pdb:3PE4|rcsb pdb:3Q04|rcsb pdb:3Q9W|rcsb pdb:3Q9X|rcsb pdb:3Q9Y|rcsb pdb:3Q9Z|rcsb pdb:3QA0|rcsb pdb:3R0T|rcsb pdb:3RPS|rcsb pdb:3TAX|rcsb pdb:3U4U|rcsb pdb:3U87|rcsb pdb:3U9C|rcsb pdb:3W8L|rcsb pdb:3WAR|rcsb pdb:3WIK|rcsb pdb:3WIL|rcsb pdb:3WOW|rcsb pdb:3PE1|rcsb pdb:4DGL|rcsb pdb:4FBX|ensembl:ENSG00000101266(gene)|ensembl:ENST00000217244(transcript)|ensembl:ENST00000400217(transcript)|ensembl:ENST00000643660(transcript)|ensembl:ENST00000645623(transcript)|ensembl:ENST00000646305(transcript)|ensembl:ENST00000646561(transcript)|ensembl:ENST00000646814(transcript)|ensembl:ENST00000647348(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016301"(kinase activity)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|rcsb pdb:4GUB|rcsb pdb:4GYW|rcsb pdb:4GYY|rcsb pdb:4GZ3|rcsb pdb:4IB5|rcsb pdb:4KWP|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|rcsb pdb:4RLL|rcsb pdb:4UB7|rcsb pdb:4GRB|rcsb pdb:4UBA|rcsb pdb:5B0X|rcsb pdb:5CLP|rcsb pdb:5CQU|rcsb pdb:5CQW|rcsb pdb:5CS6|rcsb pdb:5CSH|rcsb pdb:5CSP|rcsb pdb:5CSV|rcsb pdb:7BU4|rcsb pdb:7B8I|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:5CTP|rcsb pdb:5CU0|rcsb pdb:5CU2|rcsb pdb:5CU3|rcsb pdb:5CU4|rcsb pdb:5CU6|rcsb pdb:5CVF|rcsb pdb:5CVG|rcsb pdb:5CVH|rcsb pdb:5CX9|rcsb pdb:5H8B|rcsb pdb:5H8E|rcsb pdb:5H8G|rcsb pdb:5HGV|rcsb pdb:5KU8|rcsb pdb:5KWH|rcsb pdb:5M44|rcsb pdb:5M4C|rcsb pdb:5M4F|rcsb pdb:5M4I|rcsb pdb:5MMF|rcsb pdb:5MMR|rcsb pdb:5MO5|rcsb pdb:5MO6|rcsb pdb:5MO7|rcsb pdb:5MO8|rcsb pdb:5MOD|rcsb pdb:5MOE|rcsb pdb:5MOH|rcsb pdb:5MOT|rcsb pdb:5MOV|rcsb pdb:5MOW|rcsb pdb:5MP8|rcsb pdb:5MPJ|rcsb pdb:5N1V|rcsb pdb:5N9K|rcsb pdb:5N9L|rcsb pdb:5N9N|rcsb pdb:5NQC|rcsb pdb:5OMY|rcsb pdb:5ONI|rcsb pdb:5OQU|rcsb pdb:5ORH|rcsb pdb:5ORJ|rcsb pdb:5ORK|rcsb pdb:5CT0|rcsb pdb:5OT6|rcsb pdb:5OTD|rcsb pdb:5OTH|rcsb pdb:5OTI|rcsb pdb:5OTL|rcsb pdb:5OTO|rcsb pdb:5OTP|rcsb pdb:5OTQ|rcsb pdb:5OTR|rcsb pdb:5OTS|rcsb pdb:5OTY|rcsb pdb:5OTZ|rcsb pdb:5OUE|rcsb pdb:5OS7|rcsb pdb:5OUL|rcsb pdb:5OUM|rcsb pdb:5OS8|rcsb pdb:5OUU|rcsb pdb:5OWH|rcsb pdb:5OSL|rcsb pdb:5OWL|rcsb pdb:5OSP|rcsb pdb:5OYF|rcsb pdb:5T1H|rcsb pdb:5VIE|rcsb pdb:5VIF|rcsb pdb:5ZN0|rcsb pdb:5ZN1|rcsb pdb:5OSR|rcsb pdb:5OSU|rcsb pdb:5OSZ|rcsb pdb:5ZN2|rcsb pdb:5OT5|rcsb pdb:5ZN3|rcsb pdb:5ZN4|rcsb pdb:5ZN5|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P68400|rcsb pdb:1JWH|rcsb pdb:1NA7|rcsb pdb:1PJK|rcsb pdb:2PVR|rcsb pdb:2ZJW|rcsb pdb:3AMY|rcsb pdb:3AT2|rcsb pdb:3AT3|rcsb pdb:3AT4|rcsb pdb:3AXW|rcsb pdb:3BQC|rcsb pdb:3C13|rcsb pdb:3FWQ|rcsb pdb:3H30|rcsb pdb:3JUH|rcsb pdb:3MB6|rcsb pdb:3MB7|rcsb pdb:3NGA|rcsb pdb:3NSZ|interpro:IPR011009(Protein kinase-like)|rcsb pdb:3OWJ|rcsb pdb:3OWK|rcsb pdb:3OWL|rcsb pdb:6E37|rcsb pdb:6EHK|rcsb pdb:6EHU|rcsb pdb:6EII|rcsb pdb:6FVF|rcsb pdb:6FVG|rcsb pdb:6GIH|rcsb pdb:6GMD|rcsb pdb:6HBN|rcsb pdb:6HME|rcsb pdb:6HNW|rcsb pdb:6HNY|rcsb pdb:6HOP|rcsb pdb:6HOQ|rcsb pdb:6HOR|rcsb pdb:6HOT|rcsb pdb:6HOU|rcsb pdb:6JWA|rcsb pdb:6L1Z|rcsb pdb:6L21|rcsb pdb:6L22|rcsb pdb:6L23|rcsb pdb:6L24|rcsb pdb:6Q38|rcsb pdb:6Q4Q|rcsb pdb:6QY7|rcsb pdb:6RB1|rcsb pdb:6RCB|rcsb pdb:6RCM|rcsb pdb:6RFE|rcsb pdb:6RFF|rcsb pdb:6SPW|rcsb pdb:6A1C|rcsb pdb:6SPX|rcsb pdb:6TEI|rcsb pdb:6TLL|rcsb pdb:6TLO|rcsb pdb:6TLP|refseq:NP_001886.1|refseq:NP_808227.1|refseq:NP_808228.1|dip:DIP-32682N - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:5PLQNJJpbPzJhA0sqogKhl9umIQ9606 rigid:6R3X3L39NBQo+KQYhJyqQV17Yc4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:P23258 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-302589|ensembl:ENSP00000251413|uniprotkb:Q9BW59|uniprotkb:Q53X79 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:tbg1_human(display_long)|uniprotkb:TUBG1(gene name)|psi-mi:TUBG1(display_short)|uniprotkb:TUBG(gene name synonym)|uniprotkb:Gamma-1-tubulin(gene name synonym)|uniprotkb:Gamma-tubulin complex component 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484183|imex:IM-26985-205 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity) interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P23258|rcsb pdb:1Z5V|rcsb pdb:1Z5W|rcsb pdb:3CB2|rcsb pdb:6V5V|rcsb pdb:6V6S|rcsb pdb:7AS4|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|interpro:IPR017975|reactome:R-HSA-5620912|reactome:R-HSA-8854518|ensembl:ENSG00000131462(gene)|ensembl:ENST00000251413(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000242"(pericentriolar material)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005827"(polar microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0055037"(recycling endosome)|go:"GO:0097730"(non-motile cilium)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR000217(Tubulin)|interpro:IPR002454(Gamma tubulin)|go:"GO:0005814"(centriole)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|refseq:NP_001061.2|dip:DIP-29890N - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:Y5WLH1ZKlS7FOa9ePmH3dpdE8Xk9606 rigid:6R3X3L39NBQo+KQYhJyqQV17Yc4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:P61962 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-359808|uniprotkb:O15491|uniprotkb:Q9DAE4|uniprotkb:D3DU14|ensembl:ENSP00000402312|ensembl:ENSP00000483236|uniprotkb:B4E039 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:dcaf7_human(display_long)|uniprotkb:DCAF7(gene name)|psi-mi:DCAF7(display_short)|uniprotkb:HAN11(gene name synonym)|uniprotkb:WD repeat-containing protein An11 homolog(gene name synonym)|uniprotkb:WDR68(gene name synonym)|uniprotkb:WD repeat-containing protein 68(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484183|imex:IM-26985-205 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_005819.3|ensembl:ENSG00000136485(gene)|ensembl:ENST00000431926(transcript)|ensembl:ENST00000614556(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:P61962|reactome:R-HSA-390471|reactome:R-HSA-8951664|dip:DIP-40363N - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:wDucyMrZBaqRcL25mMGhB4KXQtI9606 rigid:6R3X3L39NBQo+KQYhJyqQV17Yc4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:Q8IWI9 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-2815196|uniprotkb:E7ENI0|uniprotkb:F5H7K2|uniprotkb:Q9H9N7|uniprotkb:Q9H8R3|uniprotkb:Q9Y4E9|uniprotkb:Q9UG69|intact:EBI-11143500|intact:EBI-10969960|ensembl:ENSP00000219905|uniprotkb:B9EGR5 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:mgap_human(display_long)|uniprotkb:MGA(gene name)|psi-mi:MGA(display_short)|uniprotkb:KIAA0518(gene name synonym)|uniprotkb:MAD5(gene name synonym)|uniprotkb:MAX dimerization protein 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484183|imex:IM-26985-205 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_001074010.2|ensembl:ENSP00000219905|ensembl:ENST00000566586|ensembl:ENSP00000456141|ensembl:ENSG00000174197(gene)|ensembl:ENST00000219905(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR018186|interpro:IPR032060|interpro:IPR036638|interpro:IPR036960|interpro:IPR037935|mint:Q8IWI9|reactome:R-HSA-8953750|refseq:NP_001157745.1|dip:DIP-57615N - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:P4lo9EteCvikQQk5kyVkcobitLU9606 rigid:6R3X3L39NBQo+KQYhJyqQV17Yc4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:Q13185 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484183|imex:IM-26985-205 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity) go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N - - comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rigid:6R3X3L39NBQo+KQYhJyqQV17Yc4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:P19784 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-347451|ensembl:ENSP00000262506 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:csk22_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)|uniprotkb:CK2A2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484183|imex:IM-26985-205 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_001887.1|dip:DIP-318N|ensembl:ENSG00000070770(gene)|ensembl:ENST00000262506(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19784|rcsb pdb:3E3B|rcsb pdb:3OFM|rcsb pdb:3U87|rcsb pdb:5M4U|rcsb pdb:5M56|rcsb pdb:5OOI|rcsb pdb:5Y9M|rcsb pdb:5YF9|rcsb pdb:5YWM|rcsb pdb:6HMB|rcsb pdb:6HMC|rcsb pdb:6HMD|rcsb pdb:6HMQ|rcsb pdb:6L20|rcsb pdb:6QY8|rcsb pdb:6QY9|rcsb pdb:6TE2|rcsb pdb:6TEW|rcsb pdb:6TGU|rcsb pdb:7A1B|rcsb pdb:7A1Z|rcsb pdb:7A22|rcsb pdb:7A2H|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751 - - comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:SIekW2yzNePP9hLKW7OHNFBwNck9606 rigid:6R3X3L39NBQo+KQYhJyqQV17Yc4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:Q5H9F3 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-8833946|uniprotkb:Q5H9F4|uniprotkb:Q9Y528|uniprotkb:Q8TEN3|uniprotkb:B5MDQ8|uniprotkb:Q6ZVE0|uniprotkb:Q5H9F2|ensembl:ENSP00000218147|ensembl:ENSP00000437775 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:bcorl_human(display_long)|uniprotkb:BCORL1(gene name)|psi-mi:BCORL1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484183|imex:IM-26985-205 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity) ensembl:ENSP00000218147|ensembl:ENSP00000437775|refseq:NP_068765.3|dip:DIP-60148N|ensembl:ENSG00000085185(gene)|ensembl:ENST00000218147(transcript)|ensembl:ENST00000540052(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006325"(chromatin organization)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q5H9F3|rcsb pdb:4HPM|rcsb pdb:5JH5 - - comment:"author score: 38" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:uQdpjjO3QnnX19nR1Ky76HjCdhw9606 rigid:6R3X3L39NBQo+KQYhJyqQV17Yc4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:P63208 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-307486|uniprotkb:P34991|uniprotkb:Q8TAY2|uniprotkb:D3DQ97|uniprotkb:D3DQ98|ensembl:ENSP00000231487|ensembl:ENSP00000429686|ensembl:ENSP00000429961 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:skp1_human(display_long)|uniprotkb:SKP1(gene name)|psi-mi:SKP1(display_short)|uniprotkb:EMC19(gene name synonym)|uniprotkb:OCP2(gene name synonym)|uniprotkb:SKP1A(gene name synonym)|uniprotkb:TCEB1L(gene name synonym)|uniprotkb:Cyclin-A/CDK2-associated protein p19(gene name synonym)|uniprotkb:p19skp1(gene name synonym)|uniprotkb:RNA polymerase II elongation factor-like protein(gene name synonym)|uniprotkb:Organ of Corti protein 2(gene name synonym)|uniprotkb:Organ of Corti protein II(gene name synonym)|uniprotkb:SIII(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1-like(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484183|imex:IM-26985-205 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity) reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-1170546|reactome:R-HSA-174113|reactome:R-HSA-180534|reactome:R-HSA-187577|reactome:R-HSA-68949|reactome:R-HSA-69231|reactome:R-HSA-8854050|reactome:R-HSA-8939902|reactome:R-HSA-8951664|reactome:R-HSA-9020702|reactome:R-HSA-917937|reactome:R-HSA-9604323|reactome:R-HSA-9708530|reactome:R-HSA-983168|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-2122947|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-400253|reactome:R-HSA-5607761|refseq:NP_008861.2|refseq:NP_733779.1|ensembl:ENSG00000113558(gene)|ensembl:ENST00000353411(transcript)|ensembl:ENST00000522855(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000517625(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0031467"(Cul7-RING ubiquitin ligase complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0051457"(maintenance of protein location in nucleus)|go:"GO:0070936"(protein K48-linked ubiquitination)|go:"GO:0097602"(cullin family protein binding)|go:"GO:1904668"(positive regulation of ubiquitin protein ligase activity)|go:"GO:1990444"(F-box domain binding)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016072(SKP1 component, dimerisation)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR016897(E3 ubiquitin ligase, SCF complex, Skp subunit)|interpro:IPR036296|mint:P63208|rcsb pdb:1FQV|rcsb pdb:1FS1|rcsb pdb:1FS2|rcsb pdb:1LDK|rcsb pdb:1P22|rcsb pdb:2ASS|rcsb pdb:2AST|rcsb pdb:2E31|rcsb pdb:2E32|rcsb pdb:2OVP|rcsb pdb:2OVQ|rcsb pdb:2OVR|rcsb pdb:3L2O|rcsb pdb:3WSO|rcsb pdb:4I6J|rcsb pdb:5IBK|rcsb pdb:5JH5|rcsb pdb:5K35|rcsb pdb:5V4B|rcsb pdb:5VZT|rcsb pdb:5VZU|rcsb pdb:5XYL|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O60|rcsb pdb:6TTU|rcsb pdb:6VCD|rcsb pdb:6W66|rcsb pdb:6WCQ|rcsb pdb:6WNX|rcsb pdb:7B5L|rcsb pdb:7B5M|rcsb pdb:7B5R|reactome:R-HSA-1169091|dip:DIP-31606N - - comment:"author score: 55" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:0U28UYW/heL+7UJO5f3h8Wq+Ud09606 rigid:6R3X3L39NBQo+KQYhJyqQV17Yc4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:Q9HAH7 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-2847800|uniprotkb:Q9H9X4|uniprotkb:Q96CI9|uniprotkb:B4DP86|ensembl:ENSP00000287468 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:fbrs_human(display_long)|uniprotkb:FBRS(gene name)|psi-mi:FBRS(display_short)|uniprotkb:FBS(gene name synonym)|uniprotkb:FBS1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484183|imex:IM-26985-205 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_001098549.2|dip:DIP-61357N|ensembl:ENSG00000156860(gene)|ensembl:ENST00000287468(transcript)|interpro:IPR023246|mint:Q9HAH7 - - comment:"author score: 55" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:n1zkWAYdgwY+t7CFWg5RKO1VSfE9606 rigid:6R3X3L39NBQo+KQYhJyqQV17Yc4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:Q99496 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484183|imex:IM-26985-205 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 - - comment:"author score: 64" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rigid:6R3X3L39NBQo+KQYhJyqQV17Yc4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:Q9BYE7 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484183|imex:IM-26985-205 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N - - comment:"author score: 69" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 rigid:6R3X3L39NBQo+KQYhJyqQV17Yc4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:Q6W2J9 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-950027|ensembl:ENSP00000367705|ensembl:ENSP00000483217|ensembl:ENSP00000499892|ensembl:ENSP00000505507|ensembl:ENSP00000505761|ensembl:ENSP00000384485|uniprotkb:Q6P4B6|uniprotkb:Q7Z2K7|uniprotkb:Q8TEB4|uniprotkb:Q96DB3|uniprotkb:Q9H232|uniprotkb:Q9H233|uniprotkb:Q9HCJ7|uniprotkb:Q9NXF2|uniprotkb:Q29RF6|uniprotkb:D3DWB3|uniprotkb:D3DWB4 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:bcor_human(display_long)|uniprotkb:BCOR(gene name)|psi-mi:BCOR(display_short)|uniprotkb:KIAA1575(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484183|imex:IM-26985-205 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity) ensembl:ENSG00000183337(gene)|ensembl:ENST00000378444(transcript)|ensembl:ENST00000406200(transcript)|ensembl:ENST00000615339(transcript)|ensembl:ENST00000672922(transcript)|ensembl:ENST00000679513(transcript)|ensembl:ENST00000680831(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000415"(negative regulation of histone H3-K36 methylation)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0042476"(odontogenesis)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0060021"(roof of mouth development)|go:"GO:0065001"(specification of axis polarity)|go:"GO:0070171"(negative regulation of tooth mineralization)|go:"GO:0140261"(BCOR complex)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR031628|interpro:IPR032365|interpro:IPR036770|interpro:IPR038227|mint:Q6W2J9|rcsb pdb:2N1L|rcsb pdb:3BIM|rcsb pdb:4HPL|rcsb pdb:6B7G|refseq:NP_001116855.1|refseq:NP_001116856.1|refseq:NP_001116857.1|refseq:NP_060215.4|refseq:XP_016885104.1|refseq:XP_011542231.1|refseq:XP_011542232.1|refseq:XP_011542233.1|refseq:XP_005272673.1|refseq:XP_005272675.1|refseq:XP_005272677.1|refseq:XP_006724599.1|dip:DIP-50009N - - comment:"author score: 74" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:FSB8ZXs8KYlWXPn3j/ocKoHAHHU9606 rigid:6R3X3L39NBQo+KQYhJyqQV17Yc4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:P35227 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-2129767|uniprotkb:A6NGD8|ensembl:ENSP00000478517|ensembl:ENSP00000478970|ensembl:ENSP00000482063|ensembl:ENSP00000482815|ensembl:ENSP00000488868|ensembl:ENSP00000488872 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:pcgf2_human(display_long)|uniprotkb:PCGF2(gene name)|psi-mi:PCGF2(display_short)|uniprotkb:MEL18(gene name synonym)|uniprotkb:RNF110(gene name synonym)|uniprotkb:ZNF144(gene name synonym)|uniprotkb:DNA-binding protein Mel-18(gene name synonym)|uniprotkb:RING finger protein 110(gene name synonym)|uniprotkb:Zinc finger protein 144(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484183|imex:IM-26985-205 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_009075.1|refseq:XP_016880505.1|refseq:XP_005257697.1|refseq:XP_005257698.1|refseq:XP_005257699.1|dip:DIP-41880N|ensembl:ENSG00000277258(gene)|ensembl:ENSG00000278644(gene)|ensembl:ENST00000610440(transcript)|ensembl:ENST00000611883(transcript)|ensembl:ENST00000616199(transcript)|ensembl:ENST00000620225(transcript)|ensembl:ENST00000631566(transcript)|ensembl:ENST00000631610(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001739"(sex chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35227|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-5617472|reactome:R-HSA-8953750 - - comment:"author score: 79" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:zppw56VrEl6gEFwtJMCN5cQkPxI9606 rigid:6R3X3L39NBQo+KQYhJyqQV17Yc4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:Q3KNV8 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-2339807|uniprotkb:O15262|uniprotkb:D3DVN1|ensembl:ENSP00000354724|ensembl:ENSP00000420489 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:pcgf3_human(display_long)|uniprotkb:PCGF3(gene name)|psi-mi:PCGF3(display_short)|uniprotkb:RNF3(gene name synonym)|uniprotkb:RNF3A(gene name synonym)|uniprotkb:RING finger protein 3A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484183|imex:IM-26985-205 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_006306.2|refseq:NP_001304765.1|dip:DIP-52782N|ensembl:ENSG00000185619(gene)|ensembl:ENST00000362003(transcript)|ensembl:ENST00000470161(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q3KNV8 - - comment:"author score: 80" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:Bt8LrtCWwivVQtfvjHQnhvrWli49606 rigid:6R3X3L39NBQo+KQYhJyqQV17Yc4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:Q9BSM1 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-749901|uniprotkb:Q7Z506|ensembl:ENSP00000233630 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:pcgf1_human(display_long)|uniprotkb:RING finger protein 68(gene name synonym)|uniprotkb:Nervous system Polycomb-1(gene name synonym)|uniprotkb:PCGF1(gene name)|psi-mi:PCGF1(display_short)|uniprotkb:NSPC1(gene name synonym)|uniprotkb:RNF68(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484183|imex:IM-26985-205 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_116062.2|dip:DIP-52708N|ensembl:ENSG00000115289(gene)|ensembl:ENST00000233630(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0046872"(metal ion binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q9BSM1|rcsb pdb:4HPL|rcsb pdb:4HPM|rcsb pdb:5JH5 - - comment:"author score: 93" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:wDCelsAlGM4be6FLYjSXeTkRuI09606 rigid:6R3X3L39NBQo+KQYhJyqQV17Yc4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:Q86SE9 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-2827999|uniprotkb:Q86TD0|uniprotkb:Q6PK47|uniprotkb:B7Z892|uniprotkb:D3DR33|ensembl:ENSP00000337500|ensembl:ENSP00000445704|ensembl:ENSP00000479492 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:pcgf5_human(display_long)|uniprotkb:PCGF5(gene name)|psi-mi:PCGF5(display_short)|uniprotkb:RNF159(gene name synonym)|uniprotkb:RING finger protein 159(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484183|imex:IM-26985-205 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_001244030.1|refseq:XP_011538573.1|refseq:NP_115749.2|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:Q86SE9|rcsb pdb:4S3O|reactome:R-HSA-8939243|interpro:IPR001841(Zinc finger, RING-type)|ensembl:ENSG00000180628(gene)|ensembl:ENST00000336126(transcript)|ensembl:ENST00000543648(transcript)|ensembl:ENST00000614189(transcript)|go:"GO:0000805"(X chromosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0060819"(inactivation of X chromosome by genomic imprinting)|refseq:NP_001243478.1|refseq:XP_016872265.1|dip:DIP-61356N - - comment:"author score: 95" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:wacR2KFFkpiK0bsbQgQAJRdYeOY9606 rigid:6R3X3L39NBQo+KQYhJyqQV17Yc4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N488 uniprotkb:P35226 intact:EBI-752324|uniprotkb:Q9P2W5|uniprotkb:Q9UMW4|ensembl:ENSP00000419494 intact:EBI-2341576|uniprotkb:Q5T8Z3|uniprotkb:Q96F37|uniprotkb:Q16030|intact:EBI-28989037|ensembl:ENSP00000365851 psi-mi:rybp_human(display_long)|uniprotkb:Death effector domain-associated factor(gene name synonym)|uniprotkb:YY1 and E4TF1-associated factor 1(gene name synonym)|uniprotkb:Apoptin-associating protein 1(gene name synonym)|uniprotkb:RYBP(gene name)|psi-mi:RYBP(display_short)|uniprotkb:DEDAF(gene name synonym)|uniprotkb:YEAF1(gene name synonym) psi-mi:bmi1_human(display_long)|uniprotkb:BMI1(gene name)|psi-mi:BMI1(display_short)|uniprotkb:PCGF4(gene name synonym)|uniprotkb:RNF51(gene name synonym)|uniprotkb:Polycomb group RING finger protein 4(gene name synonym)|uniprotkb:RING finger protein 51(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484183|imex:IM-26985-205 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036366.3|dip:DIP-41435N|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0007275"(multicellular organism development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR033774|interpro:IPR036443|interpro:IPR039958|mint:Q8N488|rcsb pdb:3IXS|reactome:R-HSA-8939243|reactome:R-HSA-8953750|ensembl:ENSG00000163602(gene)|ensembl:ENST00000477973(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity) refseq:NP_001190991.1|refseq:NP_005171.4|ensembl:ENSP00000365851|dip:DIP-41879N|ensembl:ENSG00000168283(gene)|ensembl:ENST00000376663(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006306"(DNA methylation)|go:"GO:0006342"|go:"GO:0006959"(humoral immune response)|go:"GO:0007379"(segment specification)|go:"GO:0007420"(brain development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016573"(histone acetylation)|go:"GO:0016604"(nuclear body)|go:"GO:0021903"(rostrocaudal neural tube patterning)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031519"(PcG protein complex)|go:"GO:0033092"(positive regulation of immature T cell proliferation in thymus)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071535"(RING-like zinc finger domain binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000011"(regulation of adaxial/abaxial pattern formation)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|mint:P35226|rcsb pdb:2H0D|rcsb pdb:2NA1|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:5FR6|rcsb pdb:6WI7|rcsb pdb:6WI8|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 - - comment:"author score: 105" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:t9ef8aO/5xEAB3hMlElJCktEIOU9606 rogid:ruyez2gHfd/si8gxYUDZzZ1L4689606 rigid:6R3X3L39NBQo+KQYhJyqQV17Yc4 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92541 uniprotkb:Q92598 intact:EBI-1055239|uniprotkb:Q96BX6|ensembl:ENSP00000374280 intact:EBI-356829|uniprotkb:O95739|uniprotkb:Q5TBM6|uniprotkb:Q5TBM8|uniprotkb:Q9UPC4|uniprotkb:Q5TBM7|intact:EBI-2859494|uniprotkb:B4DYH1|ensembl:ENSP00000318687 psi-mi:rtf1_human(display_long)|uniprotkb:RTF1(gene name)|psi-mi:RTF1(display_short)|uniprotkb:KIAA0252(gene name synonym) psi-mi:hs105_human(display_long)|uniprotkb:HSPH1(gene name)|psi-mi:HSPH1(display_short)|uniprotkb:HSP105(gene name synonym)|uniprotkb:HSP110(gene name synonym)|uniprotkb:KIAA0201(gene name synonym)|uniprotkb:Heat shock 110 kDa protein(gene name synonym)|uniprotkb:Antigen NY-CO-25(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484168|imex:IM-26985-433 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055953.3|ensembl:ENSG00000137815(gene)|ensembl:ENST00000389629(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001832"(blastocyst growth)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|interpro:IPR004343(Plus-3)|interpro:IPR036128|mint:Q92541|rcsb pdb:2BZE|rcsb pdb:2DB9|rcsb pdb:3U1U|rcsb pdb:4L1P|rcsb pdb:4L1U|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654 refseq:NP_001273432.1|refseq:NP_001273433.1|refseq:NP_001273434.1|refseq:NP_006635.2|ensembl:ENSG00000120694(gene)|ensembl:ENST00000320027(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045345"(positive regulation of MHC class I biosynthetic process)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051135"(positive regulation of NK T cell activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071682"(endocytic vesicle lumen)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042053|interpro:IPR043129|mint:Q92598|rcsb pdb:6GFA|reactome:R-HSA-3000484|reactome:R-HSA-3371453 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:uWqJdVWJE0snWuZCdF0OkVWXRuI9606 rogid:FSdvp2KDHLmNpceRJ9HLY5IBfQA9606 rigid:euFDbZbWrmOKQLYnFWq2fmCFF0g false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92541 uniprotkb:O75340 intact:EBI-1055239|uniprotkb:Q96BX6|ensembl:ENSP00000374280 intact:EBI-352915|uniprotkb:E7ESR3|uniprotkb:Q5TZS0|uniprotkb:B2RD16|uniprotkb:Q2YDC2|ensembl:ENSP00000264933 psi-mi:rtf1_human(display_long)|uniprotkb:RTF1(gene name)|psi-mi:RTF1(display_short)|uniprotkb:KIAA0252(gene name synonym) psi-mi:pdcd6_human(display_long)|uniprotkb:PDCD6(gene name)|psi-mi:PDCD6(display_short)|uniprotkb:ALG2(gene name synonym)|uniprotkb:Apoptosis-linked gene 2 protein homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484168|imex:IM-26985-433 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055953.3|ensembl:ENSG00000137815(gene)|ensembl:ENST00000389629(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001832"(blastocyst growth)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|interpro:IPR004343(Plus-3)|interpro:IPR036128|mint:Q92541|rcsb pdb:2BZE|rcsb pdb:2DB9|rcsb pdb:3U1U|rcsb pdb:4L1P|rcsb pdb:4L1U|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654 go:"GO:0036324"(vascular endothelial growth factor receptor-2 signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:O75340|rcsb pdb:2ZN8|rcsb pdb:2ZN9|rcsb pdb:2ZND|rcsb pdb:2ZNE|rcsb pdb:2ZRS|rcsb pdb:2ZRT|rcsb pdb:3AAJ|rcsb pdb:3AAK|rcsb pdb:3WXA|rcsb pdb:5GQQ|go:"GO:0046983"(protein dimerization activity)|refseq:NP_037364.1|refseq:NP_001254485.1|refseq:NP_001254486.1|refseq:NP_001254487.1|refseq:NP_001254488.1|ensembl:ENSG00000249915(gene)|ensembl:ENST00000264933(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0014029"(neural crest formation)|go:"GO:0014032"(neural crest cell development)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0034605"(cellular response to heat)|dip:DIP-33217N - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:uWqJdVWJE0snWuZCdF0OkVWXRuI9606 rogid:qbNAx73X9TJNr0MVNcy7Q9qN3Hg9606 rigid:euFDbZbWrmOKQLYnFWq2fmCFF0g false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92541 uniprotkb:Q8N7H5 intact:EBI-1055239|uniprotkb:Q96BX6|ensembl:ENSP00000374280 intact:EBI-2607770|uniprotkb:O75239|uniprotkb:Q9H166|uniprotkb:Q9NUU9|ensembl:ENSP00000221265|uniprotkb:M0QX35 psi-mi:rtf1_human(display_long)|uniprotkb:RTF1(gene name)|psi-mi:RTF1(display_short)|uniprotkb:KIAA0252(gene name synonym) psi-mi:paf1_human(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:PD2(gene name synonym)|uniprotkb:Pancreatic differentiation protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484168|imex:IM-26985-433 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055953.3|ensembl:ENSG00000137815(gene)|ensembl:ENST00000389629(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001832"(blastocyst growth)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|interpro:IPR004343(Plus-3)|interpro:IPR036128|mint:Q92541|rcsb pdb:2BZE|rcsb pdb:2DB9|rcsb pdb:3U1U|rcsb pdb:4L1P|rcsb pdb:4L1U|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654 refseq:NP_061961.2|ensembl:ENSG00000006712(gene)|ensembl:ENST00000221265(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030054"(cell junction)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|mint:Q8N7H5|rcsb pdb:4M6T|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|refseq:NP_001243755.1|dip:DIP-48673N - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:uWqJdVWJE0snWuZCdF0OkVWXRuI9606 rogid:5Bf9gSdxgaufI30DVL8QAyVLqNk9606 rigid:euFDbZbWrmOKQLYnFWq2fmCFF0g false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01105 uniprotkb:Q9NQ55 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-1048540|uniprotkb:Q9BW97|uniprotkb:Q9H170|uniprotkb:C9J3F9|ensembl:ENSP00000253107 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:ssf1_human(display_long)|uniprotkb:Peter Pan homolog(gene name synonym)|uniprotkb:PPAN(gene name)|psi-mi:PPAN(display_short)|uniprotkb:SSF1(gene name synonym)|uniprotkb:BXDC3(gene name synonym)|uniprotkb:Brix domain-containing protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484384|imex:IM-26985-277 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_001035754.1|refseq:NP_064615.3|ensembl:ENSG00000130810(gene)|ensembl:ENST00000253107(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0019843"(rRNA binding)|go:"GO:0030687"(preribosome, large subunit precursor)|interpro:IPR007109(Brix)|mint:Q9NQ55 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:wIgMQj/xJrj5eExsyZD6BeamQOQ9606 rigid:qpxajpn7J22Z16ai4A09P/gmqWQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01105 uniprotkb:Q9NVP1 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-724378|ensembl:ENSP00000263239|uniprotkb:Q6GTZ9|uniprotkb:Q6IAU4|uniprotkb:Q92732|uniprotkb:Q9BQB7 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:ddx18_human(display_long)|uniprotkb:DEAD box protein 18(gene name synonym)|uniprotkb:Myc-regulated DEAD box protein(gene name synonym)|uniprotkb:DDX18(gene name)|psi-mi:DDX18(display_short)|uniprotkb:cPERP-D(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484384|imex:IM-26985-277 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_006764.3|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR025313|interpro:IPR027417|interpro:IPR044773|mint:Q9NVP1|rcsb pdb:3LY5|ensembl:ENSG00000088205(gene)|ensembl:ENST00000263239(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0071392"(cellular response to estradiol stimulus) - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:RmupZbt33/w1V7Uq5vnRO36j2Tc9606 rigid:qpxajpn7J22Z16ai4A09P/gmqWQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01105 uniprotkb:Q9GZR7 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-713081|ensembl:ENSP00000481495|ensembl:ENSP00000482106|uniprotkb:E7EMJ4|uniprotkb:Q4V9L5 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:ddx24_human(display_long)|uniprotkb:DEAD box protein 24(gene name synonym)|uniprotkb:DDX24(gene name)|psi-mi:DDX24(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484384|imex:IM-26985-277 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) ensembl:ENSG00000089737(gene)|ensembl:ENSG00000273761(gene)|ensembl:ENST00000613280(transcript)|ensembl:ENST00000621632(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR027417|mint:Q9GZR7|refseq:NP_065147.1|dip:DIP-47301N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:n9gQabTC50Y/LtGMAMFNVgj12as9606 rigid:qpxajpn7J22Z16ai4A09P/gmqWQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01105 uniprotkb:Q13823 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-1043365|uniprotkb:Q9BWN7|ensembl:ENSP00000362153 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:nog2_human(display_long)|uniprotkb:Autoantigen NGP-1(gene name synonym)|uniprotkb:GNL2(gene name)|psi-mi:GNL2(display_short)|uniprotkb:NGP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484384|imex:IM-26985-277 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) ensembl:ENSG00000134697(gene)|ensembl:ENST00000373062(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0042254"(ribosome biogenesis)|interpro:IPR006073(GTP1/OBG)|interpro:IPR012971(NGP1, N-terminal)|interpro:IPR023179|interpro:IPR024929|interpro:IPR027417|interpro:IPR030378|mint:Q13823|rcsb pdb:6LSS|rcsb pdb:6LU8|refseq:NP_037417.1 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:CgIg/QNhk71SHIhV4iLvIuC/HUo9606 rigid:qpxajpn7J22Z16ai4A09P/gmqWQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01105 uniprotkb:P55084 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-356635|uniprotkb:Q9T2V8|uniprotkb:O14969|uniprotkb:Q53TA6|uniprotkb:Q96C77|uniprotkb:Q9H3F5|uniprotkb:B2RB16|intact:EBI-2948478|ensembl:ENSP00000325136|intact:EBI-8012123|intact:MINT-8395035|uniprotkb:B4E2W0 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:echb_human(display_long)|uniprotkb:HADHB(gene name)|psi-mi:HADHB(display_short)|uniprotkb:MSTP029(orf name)|uniprotkb:TP-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484384|imex:IM-26985-277 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_000174.1|ensembl:ENSG00000138029(gene)|ensembl:ENST00000317799(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003857"(3-hydroxyacyl-CoA dehydrogenase activity)|go:"GO:0003988"(acetyl-CoA C-acyltransferase activity)|go:"GO:0004300"(enoyl-CoA hydratase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005740"(mitochondrial envelope)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0006635"(fatty acid beta-oxidation)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0050633"(acetyl-CoA C-myristoyltransferase activity)|interpro:IPR002155(Thiolase)|interpro:IPR016039(Thiolase-like)|interpro:IPR020610|interpro:IPR020613|interpro:IPR020615|interpro:IPR020616|interpro:IPR020617|mint:P55084|rcsb pdb:5ZQZ|rcsb pdb:5ZRV|rcsb pdb:6DV2|reactome:R-HSA-1482798|reactome:R-HSA-77285|reactome:R-HSA-77288|reactome:R-HSA-77305|reactome:R-HSA-77310|reactome:R-HSA-77346|reactome:R-HSA-77348|reactome:R-HSA-77350|refseq:XP_011531105.1|refseq:NP_001268441.1|refseq:NP_001268442.1 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:4w0QYaw1wLyr5NJOKZ9naymK8kg9606 rigid:qpxajpn7J22Z16ai4A09P/gmqWQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01105 uniprotkb:P62750 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-353254|uniprotkb:P29316|uniprotkb:Q92774|uniprotkb:P39024|uniprotkb:B2R5B2|ensembl:ENSP00000389103 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:rl23a_human(display_long)|uniprotkb:RPL23A(gene name)|psi-mi:RPL23A(display_short)|uniprotkb:Large ribosomal subunit protein uL23(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484384|imex:IM-26985-277 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|refseq:NP_000975.2|ensembl:ENSG00000198242(gene)|ensembl:ENST00000422514(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904841"(TORC2 complex binding)|interpro:IPR001014(Ribosomal protein L23, conserved site)|interpro:IPR005633(Ribosomal protein L23/L25, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR013025(Ribosomal protein L25/L23)|interpro:IPR019985|mint:P62750|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:lA1ubRFO9/Tl54Z1dKUzoCKvpAo9606 rigid:qpxajpn7J22Z16ai4A09P/gmqWQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01105 uniprotkb:Q14684 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-372051|uniprotkb:Q8TBZ4|ensembl:ENSP00000339145 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:rrp1b_human(display_long)|uniprotkb:RRP1B(gene name)|psi-mi:RRP1B(display_short)|uniprotkb:RRP1-like protein B(gene name synonym)|uniprotkb:KIAA0179(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484384|imex:IM-26985-277 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_055871.1|ensembl:ENSG00000160208(gene)|ensembl:ENST00000340648(transcript)|go:"GO:0001652"(granular component)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006397"(mRNA processing)|go:"GO:0006915"(apoptotic process)|go:"GO:0008380"(RNA splicing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0030688"(preribosome, small subunit precursor)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0098586"(cellular response to virus)|interpro:IPR010301(Nucleolar, Nop52)|mint:Q14684 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:H3sDvQUIMBW6mjqtLWQmVKQr6uY9606 rigid:qpxajpn7J22Z16ai4A09P/gmqWQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01105 uniprotkb:Q9BW19 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-2107279|uniprotkb:O60887|uniprotkb:Q14834|uniprotkb:Q4KMP0|uniprotkb:Q5SU09|uniprotkb:Q6GMS7|uniprotkb:Q6P4A5|uniprotkb:Q9UQP7|ensembl:ENSP00000363647|ensembl:ENSP00000393963|ensembl:ENSP00000407885 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:kifc1_human(display_long)|uniprotkb:KIFC1(gene name)|psi-mi:KIFC1(display_short)|uniprotkb:HSET(gene name synonym)|uniprotkb:KNSL2(gene name synonym)|uniprotkb:Kinesin-like protein 2(gene name synonym)|uniprotkb:Kinesin-related protein HSET(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484384|imex:IM-26985-277 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_002254.2|ensembl:ENSG00000204197(gene)|ensembl:ENSG00000233450(gene)|ensembl:ENSG00000237649(gene)|ensembl:ENST00000374523(transcript)|ensembl:ENST00000428849(transcript)|ensembl:ENST00000448818(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1990939"|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR036961|mint:Q9BW19|rcsb pdb:5WDH|reactome:R-HSA-6811434|reactome:R-HSA-983189 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:2gWpNwZk9kWJGVvR8xLuDPJYP4M9606 rigid:qpxajpn7J22Z16ai4A09P/gmqWQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01105 uniprotkb:O15213 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-9995439|uniprotkb:A6NDP5|uniprotkb:Q5HYZ0|uniprotkb:Q5STK5|uniprotkb:Q5STR3|ensembl:ENSP00000363746|ensembl:ENSP00000372695|ensembl:ENSP00000399454|ensembl:ENSP00000402869|ensembl:ENSP00000405614 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:wdr46_human(display_long)|uniprotkb:WDR46(gene name)|psi-mi:WDR46(display_short)|uniprotkb:BING4(gene name synonym)|uniprotkb:C6orf11(gene name synonym)|uniprotkb:WD repeat-containing protein BING4(gene name synonym)|uniprotkb:FP221(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484384|imex:IM-26985-277 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_001157739.1|refseq:NP_005443.3|ensembl:ENSG00000204221(gene)|ensembl:ENSG00000206284(gene)|ensembl:ENSG00000226916(gene)|ensembl:ENSG00000227057(gene)|ensembl:ENSG00000236222(gene)|ensembl:ENST00000374617(transcript)|ensembl:ENST00000383208(transcript)|ensembl:ENST00000432609(transcript)|ensembl:ENST00000432933(transcript)|ensembl:ENST00000457382(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0032040"(small-subunit processome)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|interpro:IPR040315|mint:O15213|reactome:R-HSA-6790901|reactome:R-HSA-6791226|interpro:IPR012952(BING4, C-terminal) - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:BYhBAazSJnKN4c7RgWU2WygOk4o9606 rigid:qpxajpn7J22Z16ai4A09P/gmqWQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01105 uniprotkb:P82664 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-1048271|uniprotkb:Q9H3E5|uniprotkb:Q9NVR3|uniprotkb:B2RE89|ensembl:ENSP00000053468 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:rt10_human(display_long)|uniprotkb:MRPS10(gene name)|psi-mi:MRPS10(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein uS10m(gene name synonym)|uniprotkb:MSTP040(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484384|imex:IM-26985-277 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_060611.2|ensembl:ENSG00000048544(gene)|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|ensembl:ENST00000053468(transcript)|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|interpro:IPR027486|interpro:IPR036838|interpro:IPR040055|mint:P82664|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|dip:DIP-50902N - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:D6kypsC/rbFvPq5Y1YX9/DXtwtk9606 rigid:qpxajpn7J22Z16ai4A09P/gmqWQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01105 uniprotkb:Q9Y2R9 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-1054973|uniprotkb:Q53GD6|uniprotkb:B2R9N5|ensembl:ENSP00000245539 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:rt07_human(display_long)|uniprotkb:bMRP-27a(gene name synonym)|uniprotkb:MRPS7(gene name)|psi-mi:MRPS7(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein uS7m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484384|imex:IM-26985-277 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_057055.2|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR000235(Ribosomal protein S7)|interpro:IPR023798|interpro:IPR036823|mint:Q9Y2R9|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|go:"GO:0003735"(structural constituent of ribosome)|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000125445(gene)|ensembl:ENST00000245539(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding) - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:hrz2XVS38Ex1z125QFx/n9oPsys9606 rigid:qpxajpn7J22Z16ai4A09P/gmqWQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01105 uniprotkb:Q13601 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-744525|intact:EBI-28971604|ensembl:ENSP00000229214|uniprotkb:Q8NEA8|uniprotkb:Q8TC37|uniprotkb:Q96AT5|uniprotkb:A0FIK6|uniprotkb:A0JLP0|uniprotkb:B2R989|uniprotkb:E7EUQ0 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:krr1_human(display_long)|uniprotkb:HIV-1 Rev-binding protein 2(gene name synonym)|uniprotkb:Rev-interacting protein 1(gene name synonym)|uniprotkb:KRR1(gene name)|psi-mi:KRR1(display_short)|uniprotkb:HRB2(gene name synonym)|uniprotkb:KRR-R motif-containing protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484384|imex:IM-26985-277 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) ensembl:ENSP00000229214|ensembl:ENST00000438169|ensembl:ENSP00000411740|ensembl:ENSG00000111615(gene)|ensembl:ENST00000229214(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0016020"(membrane)|go:"GO:0032040"(small-subunit processome)|go:"GO:0045171"(intercellular bridge)|interpro:IPR004087(K Homology)|interpro:IPR024166|interpro:IPR036612|interpro:IPR041174|mint:Q13601|refseq:NP_008974.5|reactome:R-HSA-6790901|reactome:R-HSA-6791226 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:uBKNL/aw4wEssKJulbqQVWcH7ZI9606 rigid:qpxajpn7J22Z16ai4A09P/gmqWQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01105 uniprotkb:Q9H0U9 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-2371049|uniprotkb:O75885|uniprotkb:Q5TFE6|ensembl:ENSP00000357597|ensembl:ENSP00000498597 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:tsyl1_human(display_long)|uniprotkb:TSPYL1(gene name)|psi-mi:TSPYL1(display_short)|uniprotkb:TSPYL(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484384|imex:IM-26985-277 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_003300.1|ensembl:ENSG00000189241(gene)|ensembl:ENST00000368608(transcript)|ensembl:ENST00000652202(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019899"(enzyme binding)|go:"GO:0042393"(histone binding)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q9H0U9 - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:wo2DsKIGA3gDmomoBajtGRpQpTQ9606 rigid:qpxajpn7J22Z16ai4A09P/gmqWQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01105 uniprotkb:Q00059 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-1049924|uniprotkb:Q5U0C6|uniprotkb:B5BU05|uniprotkb:A9QXC6|uniprotkb:A8MRB2|ensembl:ENSP00000420588 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:tfam_human(display_long)|uniprotkb:TCF6(gene name synonym)|uniprotkb:Mitochondrial transcription factor 1(gene name synonym)|uniprotkb:Transcription factor 6-like 2(gene name synonym)|uniprotkb:TFAM(gene name)|psi-mi:TFAM(display_short)|uniprotkb:TCF6L2(gene name synonym)|uniprotkb:Transcription factor 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484384|imex:IM-26985-277 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_003192.1|refseq:NP_001257711.1|go:"GO:0034246"(mitochondrial transcription factor activity)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|mint:Q00059|rcsb pdb:3FGH|rcsb pdb:3TMM|rcsb pdb:3TQ6|rcsb pdb:4NNU|rcsb pdb:4NOD|rcsb pdb:6ERP|rcsb pdb:6ERQ|rcsb pdb:6HB4|rcsb pdb:6HC3|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|reactome:R-HSA-163282|reactome:R-HSA-2151201|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000108064(gene)|ensembl:ENST00000487519(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001018"(mitochondrial promoter sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0006391"(transcription initiation from mitochondrial promoter)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0031072"(heat shock protein binding) - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:JqG4yJbWWsYMvex7a6GDIDxiVcs9606 rigid:qpxajpn7J22Z16ai4A09P/gmqWQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01105 uniprotkb:Q6DKI1 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-1052408|uniprotkb:Q5TFZ5|uniprotkb:Q6PEK3|uniprotkb:A8K7D4|uniprotkb:B7Z652|ensembl:ENSP00000346063|ensembl:ENSP00000418221 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:rl7l_human(display_long)|uniprotkb:RPL7L1(gene name)|psi-mi:RPL7L1(display_short)|uniprotkb:Large ribosomal subunit protein uL30-like 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484384|imex:IM-26985-277 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_940888.3|ensembl:ENSG00000146223(gene)|ensembl:ENST00000304734(transcript)|ensembl:ENST00000493763(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001825"(blastocyst formation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR005998(Ribosomal protein L7, eukaryotic)|interpro:IPR012988(Ribosomal protein L30, N-terminal)|interpro:IPR016082(Ribosomal protein L30, C-terminal)|interpro:IPR018038|interpro:IPR035808|interpro:IPR036919|interpro:IPR039699|mint:Q6DKI1|refseq:XP_016866269.1 - - comment:"author score: 27" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:hB4ePwPQxahWRS9OEEfq1nL/lk09606 rigid:qpxajpn7J22Z16ai4A09P/gmqWQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01105 uniprotkb:Q9GZR2 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-2856313|uniprotkb:Q5T8S4|uniprotkb:B2RAT2|uniprotkb:Q9GZW3|uniprotkb:Q5T8S6|uniprotkb:Q5T8S5|ensembl:ENSP00000361010|ensembl:ENSP00000486065 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:rexo4_human(display_long)|uniprotkb:REXO4(gene name)|psi-mi:REXO4(display_short)|uniprotkb:PMC2(gene name synonym)|uniprotkb:XPMC2H(gene name synonym)|uniprotkb:Exonuclease XPMC2(gene name synonym)|uniprotkb:Prevents mitotic catastrophe 2 protein homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484384|imex:IM-26985-277 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_001266278.1|refseq:NP_001266279.1|refseq:NP_001266280.1|refseq:NP_065118.2|ensembl:ENSG00000148300(gene)|ensembl:ENSG00000280706(gene)|ensembl:ENST00000371942(transcript)|ensembl:ENST00000630460(transcript)|go:"GO:0000737"(DNA catabolic process, endonucleolytic)|go:"GO:0000738"(DNA catabolic process, exonucleolytic)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006364"(rRNA processing)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0016607"(nuclear speck)|interpro:IPR013520(Exonuclease, RNase T and DNA polymerase III)|interpro:IPR034920|interpro:IPR036397|interpro:IPR037431|mint:Q9GZR2|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold) - - comment:"author score: 31" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:N0OxZ2by59SnW1Xup2iaA29RPCU9606 rigid:qpxajpn7J22Z16ai4A09P/gmqWQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01105 uniprotkb:P42766 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-356819|uniprotkb:Q4VBY5|uniprotkb:Q9BYF4|uniprotkb:Q5JTN5|uniprotkb:Q6IBC7|uniprotkb:Q96QJ7|uniprotkb:A8K4V7|ensembl:ENSP00000259469 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:rl35_human(display_long)|uniprotkb:RPL35(gene name)|psi-mi:RPL35(display_short)|uniprotkb:Large ribosomal subunit protein uL29(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484384|imex:IM-26985-277 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_009140.1|ensembl:ENSG00000136942(gene)|ensembl:ENST00000348462(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|interpro:IPR001854(Ribosomal protein L29)|interpro:IPR018254|interpro:IPR036049|mint:P42766|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - comment:"author score: 35" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:jhzt7gCff2vdUb1Ff/VTBF698Pg9606 rigid:qpxajpn7J22Z16ai4A09P/gmqWQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01105 uniprotkb:P58876 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-4409942|ensembl:ENSP00000289316|ensembl:ENSP00000367008 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:h2b1d_human(display_long)|uniprotkb:Histone H2B.b(gene name synonym)|uniprotkb:H2BC5(gene name)|psi-mi:H2BC5(display_short)|uniprotkb:H2B-clustered histone 5(gene name synonym)|uniprotkb:H2BFB(gene name synonym)|uniprotkb:HIRA-interacting protein 2(gene name synonym)|uniprotkb:HIRIP2(gene name synonym)|uniprotkb:HIST1H2BD(gene name synonym)|uniprotkb:Histone H2B.1 B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484384|imex:IM-26985-277 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:NP_066407.1|refseq:NP_619790.1|ensembl:ENSG00000158373(gene)|ensembl:ENST00000289316(transcript)|ensembl:ENST00000377777(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P58876|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|go:"GO:0005634"(nucleus) - - comment:"author score: 38" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:07VBw5MCphdkMydMOPSjVqpGriI9606 rigid:qpxajpn7J22Z16ai4A09P/gmqWQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q01105 uniprotkb:Q9BWE0 intact:EBI-1053182|uniprotkb:A5A5H4|uniprotkb:Q15541|uniprotkb:Q5VXV1|uniprotkb:Q6FHZ5|intact:EBI-2559610|uniprotkb:A6NGV1|uniprotkb:B4DUE2|intact:EBI-4290953|uniprotkb:Q5VXV2|ensembl:ENSP00000361777 intact:EBI-5458270|ensembl:ENSP00000380451|ensembl:ENSP00000388287|ensembl:ENSP00000407714|uniprotkb:D3DWZ1|uniprotkb:Q7LE03|uniprotkb:Q9BUZ6|uniprotkb:Q9NZH2|uniprotkb:Q9UMP5|uniprotkb:C9J3L7 psi-mi:set_human(display_long)|uniprotkb:Phosphatase 2A inhibitor I2PP2A(gene name synonym)|uniprotkb:Template-activating factor I(gene name synonym)|uniprotkb:HLA-DR-associated protein II(gene name synonym)|uniprotkb:PHAPII(gene name synonym)|uniprotkb:Inhibitor of granzyme A-activated DNase(gene name synonym)|uniprotkb:SET(gene name)|psi-mi:SET(display_short) psi-mi:repi1_human(display_long)|uniprotkb:REPIN1(gene name)|psi-mi:REPIN1(display_short)|uniprotkb:RIP60(gene name synonym)|uniprotkb:ZNF464(gene name synonym)|uniprotkb:60 kDa origin-specific DNA-binding protein(gene name synonym)|uniprotkb:60 kDa replication initiation region protein(gene name synonym)|uniprotkb:ATT-binding protein(gene name synonym)|uniprotkb:DHFR oribeta-binding protein RIP60(gene name synonym)|uniprotkb:Zinc finger protein 464(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484384|imex:IM-26985-277 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001116293.1|refseq:NP_003002.2|dip:DIP-33561N|refseq:NP_001234930.1|refseq:NP_001234929.1|ensembl:ENSG00000119335(gene)|ensembl:ENST00000372692(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q01105|rcsb pdb:2E50|rcsb pdb:7MTO|reactome:R-HSA-2299718|reactome:R-HSA-450520|go:"GO:0035067"(negative regulation of histone acetylation) refseq:XP_011514414.1|ensembl:ENST00000444957(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0005694"(chromosome)|go:"GO:0006260"(DNA replication)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0043035"(chromatin insulator sequence binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR039705|mint:Q9BWE0|ensembl:ENSG00000214022(gene)|ensembl:ENST00000397281(transcript)|ensembl:ENST00000425389(transcript)|refseq:NP_001093165.1|refseq:NP_001093166.1|refseq:NP_037532.2|refseq:NP_055189.2|refseq:XP_005250042.1|refseq:XP_006716010.1|refseq:XP_006716011.1|refseq:XP_006716012.1|refseq:XP_006716015.1|refseq:XP_006716016.1|refseq:XP_016867570.1|refseq:XP_016867571.1 - - comment:"author score: 51" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CBwf28rN/LSY/vhw7jxRHKP8q0k9606 rogid:Fu6BEt9A/VSbyo1a4beSLZUd0Ug9606 rigid:qpxajpn7J22Z16ai4A09P/gmqWQ false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVD3 uniprotkb:P16403 intact:EBI-11154084|ensembl:ENSP00000329189|ensembl:ENSP00000382163|uniprotkb:Q8NE19|uniprotkb:D3DSG4|uniprotkb:D3DSG2|uniprotkb:Q9BU46|uniprotkb:B4DT14 intact:EBI-358372|ensembl:ENSP00000339566|uniprotkb:A8K4I2 psi-mi:setd4_human(display_long)|uniprotkb:SETD4(gene name)|psi-mi:SETD4(display_short)|uniprotkb:C21orf18(gene name synonym)|uniprotkb:C21orf27(gene name synonym) psi-mi:h12_human(display_long)|uniprotkb:H1-2(gene name)|psi-mi:H1-2(display_short)|uniprotkb:H1F2(gene name synonym)|uniprotkb:HIST1H1C(gene name synonym)|uniprotkb:Histone H1c(gene name synonym)|uniprotkb:Histone H1d(gene name synonym)|uniprotkb:Histone H1s-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484447|imex:IM-26985-353 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001007260.1|refseq:NP_001007262.1|refseq:NP_001273681.1|refseq:NP_059134.1|refseq:XP_011527938.1|refseq:XP_011527939.1|refseq:XP_011527940.1|refseq:XP_011527941.1|refseq:XP_011527942.1|refseq:XP_011527944.1|refseq:XP_011527945.1|refseq:XP_011527946.1|ensembl:ENSG00000185917(gene)|ensembl:ENST00000332131(transcript)|ensembl:ENST00000399215(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018023"(peptidyl-lysine trimethylation)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0071863"(regulation of cell proliferation in bone marrow)|go:"GO:0097692"(histone H3-K4 monomethylation)|interpro:IPR001214(SET)|interpro:IPR015353(Rubisco LSMT substrate-binding)|interpro:IPR036464|interpro:IPR044429|mint:Q9NVD3|interpro:IPR016852(Lysine methylase, YDR198C, predicted)|refseq:XP_016883892.1|refseq:XP_016883893.1|refseq:XP_016883894.1 refseq:NP_005310.1|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P16403|reactome:R-HSA-140342|reactome:R-HSA-2559584|ensembl:ENSG00000187837(gene)|ensembl:ENST00000343677(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|dip:DIP-36359N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2021/11/30 rogid:kRLpz0/bF71oDgTln5Gg7pArmQg9606 rogid:eRT5bTyBJUg6nRANMRYZekT4N+g9606 rigid:Di2CFFsXmicZ6umGa9CqqviIl3g false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVD3 uniprotkb:O15305 intact:EBI-11154084|ensembl:ENSP00000329189|ensembl:ENSP00000382163|uniprotkb:Q8NE19|uniprotkb:D3DSG4|uniprotkb:D3DSG2|uniprotkb:Q9BU46|uniprotkb:B4DT14 intact:EBI-10182608|uniprotkb:D3DUF3|uniprotkb:B7Z6R0|uniprotkb:A8K672|ensembl:ENSP00000268261 psi-mi:setd4_human(display_long)|uniprotkb:SETD4(gene name)|psi-mi:SETD4(display_short)|uniprotkb:C21orf18(gene name synonym)|uniprotkb:C21orf27(gene name synonym) psi-mi:pmm2_human(display_long)|uniprotkb:PMM2(gene name)|psi-mi:PMM2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484447|imex:IM-26985-353 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001007260.1|refseq:NP_001007262.1|refseq:NP_001273681.1|refseq:NP_059134.1|refseq:XP_011527938.1|refseq:XP_011527939.1|refseq:XP_011527940.1|refseq:XP_011527941.1|refseq:XP_011527942.1|refseq:XP_011527944.1|refseq:XP_011527945.1|refseq:XP_011527946.1|ensembl:ENSG00000185917(gene)|ensembl:ENST00000332131(transcript)|ensembl:ENST00000399215(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018023"(peptidyl-lysine trimethylation)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0071863"(regulation of cell proliferation in bone marrow)|go:"GO:0097692"(histone H3-K4 monomethylation)|interpro:IPR001214(SET)|interpro:IPR015353(Rubisco LSMT substrate-binding)|interpro:IPR036464|interpro:IPR044429|mint:Q9NVD3|interpro:IPR016852(Lysine methylase, YDR198C, predicted)|refseq:XP_016883892.1|refseq:XP_016883893.1|refseq:XP_016883894.1 refseq:NP_000294.1|ensembl:ENSG00000140650(gene)|ensembl:ENST00000268261(transcript)|go:"GO:0004615"(phosphomannomutase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006013"(mannose metabolic process)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0009298"(GDP-mannose biosynthetic process)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046872"(metal ion binding)|interpro:IPR005002(Eukaryotic phosphomannomutase)|interpro:IPR006379(HAD-superfamily hydrolase, subfamily IIB)|interpro:IPR023214|interpro:IPR036412|interpro:IPR043169|mint:O15305|rcsb pdb:2AMY|rcsb pdb:2Q4R|reactome:R-HSA-4043911|reactome:R-HSA-446205 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2021/11/30 rogid:kRLpz0/bF71oDgTln5Gg7pArmQg9606 rogid:3PhPMapZgZUgnd1/ddww/ciXQKU9606 rigid:Di2CFFsXmicZ6umGa9CqqviIl3g false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVD3 uniprotkb:P51784 intact:EBI-11154084|ensembl:ENSP00000329189|ensembl:ENSP00000382163|uniprotkb:Q8NE19|uniprotkb:D3DSG4|uniprotkb:D3DSG2|uniprotkb:Q9BU46|uniprotkb:B4DT14 intact:EBI-306876|intact:EBI-1058416|uniprotkb:Q8IUG6|uniprotkb:Q9BWE1|uniprotkb:B2RTX1|ensembl:ENSP00000218348 psi-mi:setd4_human(display_long)|uniprotkb:SETD4(gene name)|psi-mi:SETD4(display_short)|uniprotkb:C21orf18(gene name synonym)|uniprotkb:C21orf27(gene name synonym) psi-mi:ubp11_human(display_long)|uniprotkb:USP11(gene name)|psi-mi:USP11(display_short)|uniprotkb:UHX1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 11(gene name synonym)|uniprotkb:Deubiquitinating enzyme 11(gene name synonym)|uniprotkb:Ubiquitin thioesterase 11(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484447|imex:IM-26985-353 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001007260.1|refseq:NP_001007262.1|refseq:NP_001273681.1|refseq:NP_059134.1|refseq:XP_011527938.1|refseq:XP_011527939.1|refseq:XP_011527940.1|refseq:XP_011527941.1|refseq:XP_011527942.1|refseq:XP_011527944.1|refseq:XP_011527945.1|refseq:XP_011527946.1|ensembl:ENSG00000185917(gene)|ensembl:ENST00000332131(transcript)|ensembl:ENST00000399215(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018023"(peptidyl-lysine trimethylation)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0071863"(regulation of cell proliferation in bone marrow)|go:"GO:0097692"(histone H3-K4 monomethylation)|interpro:IPR001214(SET)|interpro:IPR015353(Rubisco LSMT substrate-binding)|interpro:IPR036464|interpro:IPR044429|mint:Q9NVD3|interpro:IPR016852(Lysine methylase, YDR198C, predicted)|refseq:XP_016883892.1|refseq:XP_016883893.1|refseq:XP_016883894.1 ensembl:ENSG00000102226(gene)|ensembl:ENST00000218348(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR029346|interpro:IPR035927|interpro:IPR038765|mint:P51784|rcsb pdb:4MEL|rcsb pdb:5OK6|reactome:R-HSA-390471|reactome:R-HSA-5689880|refseq:NP_004642.2|refseq:XP_011542290.1|refseq:XP_005272731.1|dip:DIP-27567N - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2021/11/30 rogid:kRLpz0/bF71oDgTln5Gg7pArmQg9606 rogid:OSJLLFBf1ofw8SC01p2iiIM1oJo9606 rigid:Di2CFFsXmicZ6umGa9CqqviIl3g false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVD3 uniprotkb:P47929 intact:EBI-11154084|ensembl:ENSP00000329189|ensembl:ENSP00000382163|uniprotkb:Q8NE19|uniprotkb:D3DSG4|uniprotkb:D3DSG2|uniprotkb:Q9BU46|uniprotkb:B4DT14 intact:EBI-357504|ensembl:ENSP00000313571|ensembl:ENSP00000367891|ensembl:ENSP00000489395|ensembl:ENSP00000489582|uniprotkb:Q6IB87 psi-mi:setd4_human(display_long)|uniprotkb:SETD4(gene name)|psi-mi:SETD4(display_short)|uniprotkb:C21orf18(gene name synonym)|uniprotkb:C21orf27(gene name synonym) psi-mi:leg7_human(display_long)|uniprotkb:LGALS7(gene name)|psi-mi:LGALS7(display_short)|uniprotkb:PIG1(gene name synonym)|uniprotkb:HKL-14(gene name synonym)|uniprotkb:PI7(gene name synonym)|uniprotkb:p53-induced gene 1 protein(gene name synonym)|uniprotkb:LGALS7B(gene name)|psi-mi:LGALS7B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484447|imex:IM-26985-353 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001007260.1|refseq:NP_001007262.1|refseq:NP_001273681.1|refseq:NP_059134.1|refseq:XP_011527938.1|refseq:XP_011527939.1|refseq:XP_011527940.1|refseq:XP_011527941.1|refseq:XP_011527942.1|refseq:XP_011527944.1|refseq:XP_011527945.1|refseq:XP_011527946.1|ensembl:ENSG00000185917(gene)|ensembl:ENST00000332131(transcript)|ensembl:ENST00000399215(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018023"(peptidyl-lysine trimethylation)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0071863"(regulation of cell proliferation in bone marrow)|go:"GO:0097692"(histone H3-K4 monomethylation)|interpro:IPR001214(SET)|interpro:IPR015353(Rubisco LSMT substrate-binding)|interpro:IPR036464|interpro:IPR044429|mint:Q9NVD3|interpro:IPR016852(Lysine methylase, YDR198C, predicted)|refseq:XP_016883892.1|refseq:XP_016883893.1|refseq:XP_016883894.1 ensembl:ENSG00000178934(gene)|ensembl:ENSG00000205076(gene)|ensembl:ENSG00000282902(gene)|ensembl:ENSG00000283082(gene)|ensembl:ENST00000314980(transcript)|ensembl:ENST00000378626(transcript)|ensembl:ENST00000634448(transcript)|ensembl:ENST00000634800(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016936"(galactoside binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000562"(negative regulation of CD4-positive, alpha-beta T cell proliferation)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR030640|interpro:IPR044156|mint:P47929|rcsb pdb:1BKZ|rcsb pdb:2GAL|rcsb pdb:3GAL|rcsb pdb:3ZXE|rcsb pdb:3ZXF|rcsb pdb:4GAL|rcsb pdb:4UW3|rcsb pdb:4UW4|rcsb pdb:4UW5|rcsb pdb:4UW6|rcsb pdb:4XBQ|rcsb pdb:4Y26|rcsb pdb:5GAL|rcsb pdb:5H9Q|rcsb pdb:5H9S|refseq:NP_001035972.1|refseq:NP_002298.1 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2021/11/30 rogid:kRLpz0/bF71oDgTln5Gg7pArmQg9606 rogid:TIAlvVZ7rOYqTAGrYAFbJY231gc9606 rigid:Di2CFFsXmicZ6umGa9CqqviIl3g false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVD3 uniprotkb:Q9Y3U8 intact:EBI-11154084|ensembl:ENSP00000329189|ensembl:ENSP00000382163|uniprotkb:Q8NE19|uniprotkb:D3DSG4|uniprotkb:D3DSG2|uniprotkb:Q9BU46|uniprotkb:B4DT14 intact:EBI-1057689|uniprotkb:Q6FIG1|uniprotkb:Q9UQF6|uniprotkb:B2R4Y1|uniprotkb:D6W634|ensembl:ENSP00000252543|ensembl:ENSP00000378081|ensembl:ENSP00000462609|ensembl:ENSP00000464342 psi-mi:setd4_human(display_long)|uniprotkb:SETD4(gene name)|psi-mi:SETD4(display_short)|uniprotkb:C21orf18(gene name synonym)|uniprotkb:C21orf27(gene name synonym) psi-mi:rl36_human(display_long)|uniprotkb:RPL36(gene name)|psi-mi:RPL36(display_short)|uniprotkb:Large ribosomal subunit protein eL36(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484447|imex:IM-26985-353 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001007260.1|refseq:NP_001007262.1|refseq:NP_001273681.1|refseq:NP_059134.1|refseq:XP_011527938.1|refseq:XP_011527939.1|refseq:XP_011527940.1|refseq:XP_011527941.1|refseq:XP_011527942.1|refseq:XP_011527944.1|refseq:XP_011527945.1|refseq:XP_011527946.1|ensembl:ENSG00000185917(gene)|ensembl:ENST00000332131(transcript)|ensembl:ENST00000399215(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018023"(peptidyl-lysine trimethylation)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0071863"(regulation of cell proliferation in bone marrow)|go:"GO:0097692"(histone H3-K4 monomethylation)|interpro:IPR001214(SET)|interpro:IPR015353(Rubisco LSMT substrate-binding)|interpro:IPR036464|interpro:IPR044429|mint:Q9NVD3|interpro:IPR016852(Lysine methylase, YDR198C, predicted)|refseq:XP_016883892.1|refseq:XP_016883893.1|refseq:XP_016883894.1 refseq:NP_056229.2|refseq:NP_378669.1|reactome:R-HSA-975957|mint:Q9Y3U8|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|interpro:IPR038097|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|rcsb pdb:6Y6X|ensembl:ENSG00000130255(gene)|ensembl:ENST00000347512(transcript)|ensembl:ENST00000394580(transcript)|ensembl:ENST00000577222(transcript)|ensembl:ENST00000579649(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR000509(Ribosomal protein L36e) - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2021/11/30 rogid:kRLpz0/bF71oDgTln5Gg7pArmQg9606 rogid:lRlRMF2jV/UHr4SX95SSCFIEV+s9606 rigid:Di2CFFsXmicZ6umGa9CqqviIl3g false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVD3 uniprotkb:P61513 intact:EBI-11154084|ensembl:ENSP00000329189|ensembl:ENSP00000382163|uniprotkb:Q8NE19|uniprotkb:D3DSG4|uniprotkb:D3DSG2|uniprotkb:Q9BU46|uniprotkb:B4DT14 intact:EBI-356793|uniprotkb:P12751|intact:EBI-1051378|uniprotkb:Q6FGF5|ensembl:ENSP00000418082 psi-mi:setd4_human(display_long)|uniprotkb:SETD4(gene name)|psi-mi:SETD4(display_short)|uniprotkb:C21orf18(gene name synonym)|uniprotkb:C21orf27(gene name synonym) psi-mi:rl37a_human(display_long)|uniprotkb:RPL37A(gene name)|psi-mi:RPL37A(display_short)|uniprotkb:Large ribosomal subunit protein eL43(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484447|imex:IM-26985-353 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001007260.1|refseq:NP_001007262.1|refseq:NP_001273681.1|refseq:NP_059134.1|refseq:XP_011527938.1|refseq:XP_011527939.1|refseq:XP_011527940.1|refseq:XP_011527941.1|refseq:XP_011527942.1|refseq:XP_011527944.1|refseq:XP_011527945.1|refseq:XP_011527946.1|ensembl:ENSG00000185917(gene)|ensembl:ENST00000332131(transcript)|ensembl:ENST00000399215(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018023"(peptidyl-lysine trimethylation)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0071863"(regulation of cell proliferation in bone marrow)|go:"GO:0097692"(histone H3-K4 monomethylation)|interpro:IPR001214(SET)|interpro:IPR015353(Rubisco LSMT substrate-binding)|interpro:IPR036464|interpro:IPR044429|mint:Q9NVD3|interpro:IPR016852(Lysine methylase, YDR198C, predicted)|refseq:XP_016883892.1|refseq:XP_016883893.1|refseq:XP_016883894.1 refseq:NP_000989.1|ensembl:ENSG00000197756(gene)|ensembl:ENST00000491306(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002674(Ribosomal protein L37ae)|interpro:IPR011331(Ribosomal protein L37ae/L37e, core)|interpro:IPR011332(Ribosomal protein, zinc-binding)|mint:P61513|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2021/11/30 rogid:kRLpz0/bF71oDgTln5Gg7pArmQg9606 rogid:0kwO2cVd99FGF2+5FyWo94C83049606 rigid:Di2CFFsXmicZ6umGa9CqqviIl3g false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVD3 uniprotkb:P62316 intact:EBI-11154084|ensembl:ENSP00000329189|ensembl:ENSP00000382163|uniprotkb:Q8NE19|uniprotkb:D3DSG4|uniprotkb:D3DSG2|uniprotkb:Q9BU46|uniprotkb:B4DT14 intact:EBI-297993|uniprotkb:P43330|ensembl:ENSP00000342374|ensembl:ENSP00000465216|uniprotkb:A8K797|uniprotkb:J3KPM5 psi-mi:setd4_human(display_long)|uniprotkb:SETD4(gene name)|psi-mi:SETD4(display_short)|uniprotkb:C21orf18(gene name synonym)|uniprotkb:C21orf27(gene name synonym) psi-mi:smd2_human(display_long)|uniprotkb:SNRPD2(gene name)|psi-mi:SNRPD2(display_short)|uniprotkb:snRNP core protein D2(gene name synonym)|uniprotkb:SNRPD1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484447|imex:IM-26985-353 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001007260.1|refseq:NP_001007262.1|refseq:NP_001273681.1|refseq:NP_059134.1|refseq:XP_011527938.1|refseq:XP_011527939.1|refseq:XP_011527940.1|refseq:XP_011527941.1|refseq:XP_011527942.1|refseq:XP_011527944.1|refseq:XP_011527945.1|refseq:XP_011527946.1|ensembl:ENSG00000185917(gene)|ensembl:ENST00000332131(transcript)|ensembl:ENST00000399215(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018023"(peptidyl-lysine trimethylation)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0071863"(regulation of cell proliferation in bone marrow)|go:"GO:0097692"(histone H3-K4 monomethylation)|interpro:IPR001214(SET)|interpro:IPR015353(Rubisco LSMT substrate-binding)|interpro:IPR036464|interpro:IPR044429|mint:Q9NVD3|interpro:IPR016852(Lysine methylase, YDR198C, predicted)|refseq:XP_016883892.1|refseq:XP_016883893.1|refseq:XP_016883894.1 ensembl:ENSG00000125743(gene)|ensembl:ENST00000342669(transcript)|ensembl:ENST00000588301(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990446"(U1 snRNP binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027248|mint:P62316|rcsb pdb:1B34|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:NP_004588.1|refseq:NP_808210.2|dip:DIP-31219N - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2021/11/30 rogid:kRLpz0/bF71oDgTln5Gg7pArmQg9606 rogid:4OshNPT6N4dOcWMVXrF5Fm8dcnI9606 rigid:Di2CFFsXmicZ6umGa9CqqviIl3g false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NVD3 uniprotkb:Q15170 intact:EBI-11154084|ensembl:ENSP00000329189|ensembl:ENSP00000382163|uniprotkb:Q8NE19|uniprotkb:D3DSG4|uniprotkb:D3DSG2|uniprotkb:Q9BU46|uniprotkb:B4DT14 intact:EBI-2511314|uniprotkb:Q9UJQ9|intact:EBI-11156070 psi-mi:setd4_human(display_long)|uniprotkb:SETD4(gene name)|psi-mi:SETD4(display_short)|uniprotkb:C21orf18(gene name synonym)|uniprotkb:C21orf27(gene name synonym) psi-mi:tcal1_human(display_long)|uniprotkb:TCEAL1(gene name)|psi-mi:TCEAL1(display_short)|uniprotkb:SIIR(gene name synonym)|uniprotkb:Transcription elongation factor S-II protein-like 1(gene name synonym)|uniprotkb:Nuclear phosphoprotein p21/SIIR(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484447|imex:IM-26985-353 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001007260.1|refseq:NP_001007262.1|refseq:NP_001273681.1|refseq:NP_059134.1|refseq:XP_011527938.1|refseq:XP_011527939.1|refseq:XP_011527940.1|refseq:XP_011527941.1|refseq:XP_011527942.1|refseq:XP_011527944.1|refseq:XP_011527945.1|refseq:XP_011527946.1|ensembl:ENSG00000185917(gene)|ensembl:ENST00000332131(transcript)|ensembl:ENST00000399215(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018023"(peptidyl-lysine trimethylation)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0071863"(regulation of cell proliferation in bone marrow)|go:"GO:0097692"(histone H3-K4 monomethylation)|interpro:IPR001214(SET)|interpro:IPR015353(Rubisco LSMT substrate-binding)|interpro:IPR036464|interpro:IPR044429|mint:Q9NVD3|interpro:IPR016852(Lysine methylase, YDR198C, predicted)|refseq:XP_016883892.1|refseq:XP_016883893.1|refseq:XP_016883894.1 go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0050699"(WW domain binding)|interpro:IPR021156|interpro:IPR010370(Transcription elongation factor A, SII-related)|mint:Q15170 - - comment:"author score: 42" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2021/11/30 rogid:kRLpz0/bF71oDgTln5Gg7pArmQg9606 rogid:QGQDFZmacLSo79K+UBfW/ulS32E9606 rigid:Di2CFFsXmicZ6umGa9CqqviIl3g false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TBK2 uniprotkb:O75334 intact:EBI-3863032|uniprotkb:A8K380|uniprotkb:B5ME38|uniprotkb:Q9H787|ensembl:ENSP00000219315 intact:EBI-1105129|ensembl:ENSP00000450337|uniprotkb:B3KXA0|uniprotkb:B7ZKZ5|uniprotkb:F8VP68|uniprotkb:Q2M3G8|uniprotkb:B3KVT5|uniprotkb:B7Z2A6|uniprotkb:B7Z3U9|uniprotkb:B7Z663|uniprotkb:E7ERB8|uniprotkb:E7ETG6 psi-mi:setd6_human(display_long)|uniprotkb:SETD6(gene name)|psi-mi:SETD6(display_short)|uniprotkb:SET domain-containing protein 6(gene name synonym) psi-mi:lipa2_human(display_long)|uniprotkb:PPFIA2(gene name)|psi-mi:PPFIA2(display_short)|uniprotkb:Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484477|imex:IM-26985-131 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001153777.1|refseq:NP_079136.2|ensembl:ENSG00000103037(gene)|ensembl:ENST00000219315(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051059"(NF-kappaB binding)|interpro:IPR001214(SET)|interpro:IPR011383(RuBisCO-cytochrome methylase, RMS1)|interpro:IPR015353(Rubisco LSMT substrate-binding)|interpro:IPR036464|interpro:IPR044430|mint:Q8TBK2|rcsb pdb:3QXY|rcsb pdb:3RC0|reactome:R-HSA-3214841 refseq:NP_003616.2|ensembl:ENSG00000139220(gene)|ensembl:ENST00000549396(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0030424"(axon)|go:"GO:0043197"(dendritic spine)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050808"(synapse organization)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099181"(structural constituent of presynapse)|go:"GO:0099519"(dense core granule cytoskeletal transport)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029515|interpro:IPR030441|interpro:IPR037620|interpro:IPR037621|interpro:IPR037622|mint:O75334|rcsb pdb:3TAC|rcsb pdb:3TAD|rcsb pdb:6IUH|rcsb pdb:7D2E|rcsb pdb:7D2G|rcsb pdb:7D2H|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-388844|refseq:NP_001207403.1|refseq:NP_001207404.1|refseq:NP_001207405.1|refseq:NP_001207406.1|refseq:NP_001207407.1|refseq:NP_001207408.1|refseq:NP_001207409.1|refseq:XP_016875569.1|refseq:XP_016875571.1 - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:1rElWp+bPTbTW+AIwuGFyv9ZGeI9606 rogid:JWcUe5GLHo/JyakmiC91TuspElU9606 rigid:LGyj+VIDwZKcdfbGjpHylPoNCOE false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TBK2 uniprotkb:Q9Y6H1 intact:EBI-3863032|uniprotkb:A8K380|uniprotkb:B5ME38|uniprotkb:Q9H787|ensembl:ENSP00000219315 intact:EBI-2321769|uniprotkb:Q498C3|uniprotkb:Q6NZ50|ensembl:ENSP00000378812 psi-mi:setd6_human(display_long)|uniprotkb:SETD6(gene name)|psi-mi:SETD6(display_short)|uniprotkb:SET domain-containing protein 6(gene name synonym) psi-mi:chch2_human(display_long)|uniprotkb:CHCHD2(gene name)|psi-mi:CHCHD2(display_short)|uniprotkb:C7orf17(gene name synonym)|uniprotkb:HCV NS2 trans-regulated protein(gene name synonym)|uniprotkb:Aging-associated gene 10 protein(gene name synonym)|uniprotkb:AAG10(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484477|imex:IM-26985-131 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001153777.1|refseq:NP_079136.2|ensembl:ENSG00000103037(gene)|ensembl:ENST00000219315(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0048863"(stem cell differentiation)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0051059"(NF-kappaB binding)|interpro:IPR001214(SET)|interpro:IPR011383(RuBisCO-cytochrome methylase, RMS1)|interpro:IPR015353(Rubisco LSMT substrate-binding)|interpro:IPR036464|interpro:IPR044430|mint:Q8TBK2|rcsb pdb:3QXY|rcsb pdb:3RC0|reactome:R-HSA-3214841 refseq:NP_057223.1|ensembl:ENSG00000106153(gene)|ensembl:ENST00000395422(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900037"(regulation of cellular response to hypoxia)|go:"GO:1905448"(positive regulation of mitochondrial ATP synthesis coupled electron transport)|interpro:IPR010625(CHCH)|mint:Q9Y6H1|reactome:R-HSA-1268020 - - comment:"author score: 30" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:1rElWp+bPTbTW+AIwuGFyv9ZGeI9606 rogid:fdx3lE51+yZ1k3uwh8/LDKJC+CQ9606 rigid:LGyj+VIDwZKcdfbGjpHylPoNCOE false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WTS6 uniprotkb:O75688 intact:EBI-1268586|uniprotkb:Q4W5A9|uniprotkb:Q0VAH3|uniprotkb:Q9C0E6|uniprotkb:B5WWL3|ensembl:ENSP00000274031 intact:EBI-1047039|uniprotkb:Q9HAY8|uniprotkb:Q461Q2|uniprotkb:Q658R4|ensembl:ENSP00000282412|uniprotkb:Q96ER6|uniprotkb:Q4J6C1|uniprotkb:Q4J6C2 psi-mi:setd7_human(display_long)|uniprotkb:SETD7(gene name)|psi-mi:SETD7(display_short)|uniprotkb:KIAA1717(gene name synonym)|uniprotkb:SET7(gene name synonym)|uniprotkb:KMT7(gene name synonym)|uniprotkb:SET9(gene name synonym)|uniprotkb:Histone H3-K4 methyltransferase SETD7(gene name synonym)|uniprotkb:SET domain-containing protein 7(gene name synonym)|uniprotkb:SET7/9(gene name synonym)|uniprotkb:Lysine N-methyltransferase 7(gene name synonym) psi-mi:ppm1b_human(display_long)|uniprotkb:Protein phosphatase 2C isoform beta(gene name synonym)|uniprotkb:PPM1B(gene name)|psi-mi:PPM1B(display_short)|uniprotkb:PP2CB(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484489|imex:IM-26985-279 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_085151.1|dip:DIP-29045N|refseq:NP_001293128.1|ensembl:ENSG00000145391(gene)|ensembl:ENST00000274031(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0045471"(response to ethanol)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0070828"(heterochromatin organization)|interpro:IPR001214(SET)|interpro:IPR003409(MORN motif)|interpro:IPR017155(Histone-lysine N-methyltransferase, SET)|interpro:IPR044436|mint:Q8WTS6|rcsb pdb:1H3I|rcsb pdb:1MT6|rcsb pdb:1MUF|rcsb pdb:1N6A|rcsb pdb:1N6C|rcsb pdb:1O9S|rcsb pdb:1XQH|rcsb pdb:2F69|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:3M53|rcsb pdb:3M54|rcsb pdb:3M55|rcsb pdb:3M56|rcsb pdb:3M57|rcsb pdb:3M58|rcsb pdb:3M59|rcsb pdb:3M5A|rcsb pdb:3OS5|rcsb pdb:3VUZ|rcsb pdb:3VV0|rcsb pdb:4E47|rcsb pdb:4J7F|rcsb pdb:4J7I|rcsb pdb:4J83|rcsb pdb:4J8O|rcsb pdb:4JDS|rcsb pdb:4JLG|rcsb pdb:5AYF|go:"GO:0018026"(peptidyl-lysine monomethylation)|rcsb pdb:5EG2|rcsb pdb:5YLT|reactome:R-HSA-3214841 refseq:NP_001028729.1|refseq:NP_002697.1|refseq:NP_808907.1|refseq:NP_808908.1|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0050687"(negative regulation of defense response to virus)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|interpro:IPR000222(Protein phosphatase 2C, manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR012911(Protein serine/threonine phosphatase 2C, C-terminal)|interpro:IPR036457|interpro:IPR036580|mint:O75688|rcsb pdb:2P8E|reactome:R-HSA-1169408|ensembl:ENSG00000138032(gene)|ensembl:ENST00000282412(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0006499"(N-terminal protein myristoylation)|go:"GO:0016020"(membrane)|go:"GO:0030145"(manganese ion binding)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0035970"(peptidyl-threonine dephosphorylation) - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wqmjJBZrQZT1Uydm62Moi9oGNtQ9606 rogid:cwwfGSSTv9pR/XNLa9UxQ/6hpD89606 rigid:beuhgTdRtGiiLGwhMfEemmJ4iNs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WTS6 uniprotkb:Q08188 intact:EBI-1268586|uniprotkb:Q4W5A9|uniprotkb:Q0VAH3|uniprotkb:Q9C0E6|uniprotkb:B5WWL3|ensembl:ENSP00000274031 intact:EBI-1050019|uniprotkb:A8K5N6|uniprotkb:Q32MM0|uniprotkb:O95933|uniprotkb:Q32ML9|uniprotkb:B2RCR6|uniprotkb:D3DVX1|ensembl:ENSP00000370867 psi-mi:setd7_human(display_long)|uniprotkb:SETD7(gene name)|psi-mi:SETD7(display_short)|uniprotkb:KIAA1717(gene name synonym)|uniprotkb:SET7(gene name synonym)|uniprotkb:KMT7(gene name synonym)|uniprotkb:SET9(gene name synonym)|uniprotkb:Histone H3-K4 methyltransferase SETD7(gene name synonym)|uniprotkb:SET domain-containing protein 7(gene name synonym)|uniprotkb:SET7/9(gene name synonym)|uniprotkb:Lysine N-methyltransferase 7(gene name synonym) psi-mi:tgm3_human(display_long)|uniprotkb:Transglutaminase-3(gene name synonym)|uniprotkb:TGM3(gene name)|psi-mi:TGM3(display_short)|uniprotkb:Transglutaminase E(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484489|imex:IM-26985-279 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_085151.1|dip:DIP-29045N|refseq:NP_001293128.1|ensembl:ENSG00000145391(gene)|ensembl:ENST00000274031(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0045471"(response to ethanol)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0070828"(heterochromatin organization)|interpro:IPR001214(SET)|interpro:IPR003409(MORN motif)|interpro:IPR017155(Histone-lysine N-methyltransferase, SET)|interpro:IPR044436|mint:Q8WTS6|rcsb pdb:1H3I|rcsb pdb:1MT6|rcsb pdb:1MUF|rcsb pdb:1N6A|rcsb pdb:1N6C|rcsb pdb:1O9S|rcsb pdb:1XQH|rcsb pdb:2F69|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:3M53|rcsb pdb:3M54|rcsb pdb:3M55|rcsb pdb:3M56|rcsb pdb:3M57|rcsb pdb:3M58|rcsb pdb:3M59|rcsb pdb:3M5A|rcsb pdb:3OS5|rcsb pdb:3VUZ|rcsb pdb:3VV0|rcsb pdb:4E47|rcsb pdb:4J7F|rcsb pdb:4J7I|rcsb pdb:4J83|rcsb pdb:4J8O|rcsb pdb:4JDS|rcsb pdb:4JLG|rcsb pdb:5AYF|go:"GO:0018026"(peptidyl-lysine monomethylation)|rcsb pdb:5EG2|rcsb pdb:5YLT|reactome:R-HSA-3214841 refseq:NP_003236.3|ensembl:ENSG00000125780(gene)|ensembl:ENST00000381458(transcript)|go:"GO:0003810"(protein-glutamine gamma-glutamyltransferase activity)|go:"GO:0003824"(catalytic activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031424"(keratinization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043163"(cell envelope organization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001102(Transglutaminase, N-terminal)|interpro:IPR002931(Transglutaminase-like)|interpro:IPR008958(Transglutaminase, C-terminal)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013808(Transglutaminase, conserved site)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR023608|interpro:IPR036238|interpro:IPR036985|interpro:IPR038765|mint:Q08188|rcsb pdb:1L9M|rcsb pdb:1L9N|rcsb pdb:1NUD|rcsb pdb:1NUF|rcsb pdb:1NUG - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wqmjJBZrQZT1Uydm62Moi9oGNtQ9606 rogid:5UuVUvhYOaQcLJQO2myrilPgFFw9606 rigid:beuhgTdRtGiiLGwhMfEemmJ4iNs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WTS6 uniprotkb:Q13867 intact:EBI-1268586|uniprotkb:Q4W5A9|uniprotkb:Q0VAH3|uniprotkb:Q9C0E6|uniprotkb:B5WWL3|ensembl:ENSP00000274031 intact:EBI-718504|uniprotkb:Q53F86|uniprotkb:Q9UER9|uniprotkb:B2R796|ensembl:ENSP00000261714 psi-mi:setd7_human(display_long)|uniprotkb:SETD7(gene name)|psi-mi:SETD7(display_short)|uniprotkb:KIAA1717(gene name synonym)|uniprotkb:SET7(gene name synonym)|uniprotkb:KMT7(gene name synonym)|uniprotkb:SET9(gene name synonym)|uniprotkb:Histone H3-K4 methyltransferase SETD7(gene name synonym)|uniprotkb:SET domain-containing protein 7(gene name synonym)|uniprotkb:SET7/9(gene name synonym)|uniprotkb:Lysine N-methyltransferase 7(gene name synonym) psi-mi:blmh_human(display_long)|uniprotkb:BLMH(gene name)|psi-mi:BLMH(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484489|imex:IM-26985-279 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_085151.1|dip:DIP-29045N|refseq:NP_001293128.1|ensembl:ENSG00000145391(gene)|ensembl:ENST00000274031(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0045471"(response to ethanol)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0070828"(heterochromatin organization)|interpro:IPR001214(SET)|interpro:IPR003409(MORN motif)|interpro:IPR017155(Histone-lysine N-methyltransferase, SET)|interpro:IPR044436|mint:Q8WTS6|rcsb pdb:1H3I|rcsb pdb:1MT6|rcsb pdb:1MUF|rcsb pdb:1N6A|rcsb pdb:1N6C|rcsb pdb:1O9S|rcsb pdb:1XQH|rcsb pdb:2F69|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:3M53|rcsb pdb:3M54|rcsb pdb:3M55|rcsb pdb:3M56|rcsb pdb:3M57|rcsb pdb:3M58|rcsb pdb:3M59|rcsb pdb:3M5A|rcsb pdb:3OS5|rcsb pdb:3VUZ|rcsb pdb:3VV0|rcsb pdb:4E47|rcsb pdb:4J7F|rcsb pdb:4J7I|rcsb pdb:4J83|rcsb pdb:4J8O|rcsb pdb:4JDS|rcsb pdb:4JLG|rcsb pdb:5AYF|go:"GO:0018026"(peptidyl-lysine monomethylation)|rcsb pdb:5EG2|rcsb pdb:5YLT|reactome:R-HSA-3214841 refseq:NP_000377.1|ensembl:ENSG00000108578(gene)|ensembl:ENST00000261714(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0004180"(carboxypeptidase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0009636"(response to toxic substance)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043418"(homocysteine catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR004134(Peptidase C1B, bleomycin hydrolase)|interpro:IPR038765|mint:Q13867|rcsb pdb:1CB5|rcsb pdb:2CB5|reactome:R-HSA-983168 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wqmjJBZrQZT1Uydm62Moi9oGNtQ9606 rogid:THDv63DC81eQzFvmyWs1rlCBMyk9606 rigid:beuhgTdRtGiiLGwhMfEemmJ4iNs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WTS6 uniprotkb:P81605 intact:EBI-1268586|uniprotkb:Q4W5A9|uniprotkb:Q0VAH3|uniprotkb:Q9C0E6|uniprotkb:B5WWL3|ensembl:ENSP00000274031 intact:EBI-395625|uniprotkb:P58461|uniprotkb:A5JHP2|uniprotkb:A5JHP3|uniprotkb:Q53YJ2|ensembl:ENSP00000293371 psi-mi:setd7_human(display_long)|uniprotkb:SETD7(gene name)|psi-mi:SETD7(display_short)|uniprotkb:KIAA1717(gene name synonym)|uniprotkb:SET7(gene name synonym)|uniprotkb:KMT7(gene name synonym)|uniprotkb:SET9(gene name synonym)|uniprotkb:Histone H3-K4 methyltransferase SETD7(gene name synonym)|uniprotkb:SET domain-containing protein 7(gene name synonym)|uniprotkb:SET7/9(gene name synonym)|uniprotkb:Lysine N-methyltransferase 7(gene name synonym) psi-mi:dcd_human(display_long)|uniprotkb:AIDD(gene name synonym)|uniprotkb:DSEP(gene name synonym)|uniprotkb:Preproteolysin(gene name synonym)|uniprotkb:DCD(gene name)|psi-mi:DCD(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484489|imex:IM-26985-279 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_085151.1|dip:DIP-29045N|refseq:NP_001293128.1|ensembl:ENSG00000145391(gene)|ensembl:ENST00000274031(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0045471"(response to ethanol)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0070828"(heterochromatin organization)|interpro:IPR001214(SET)|interpro:IPR003409(MORN motif)|interpro:IPR017155(Histone-lysine N-methyltransferase, SET)|interpro:IPR044436|mint:Q8WTS6|rcsb pdb:1H3I|rcsb pdb:1MT6|rcsb pdb:1MUF|rcsb pdb:1N6A|rcsb pdb:1N6C|rcsb pdb:1O9S|rcsb pdb:1XQH|rcsb pdb:2F69|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:3M53|rcsb pdb:3M54|rcsb pdb:3M55|rcsb pdb:3M56|rcsb pdb:3M57|rcsb pdb:3M58|rcsb pdb:3M59|rcsb pdb:3M5A|rcsb pdb:3OS5|rcsb pdb:3VUZ|rcsb pdb:3VV0|rcsb pdb:4E47|rcsb pdb:4J7F|rcsb pdb:4J7I|rcsb pdb:4J83|rcsb pdb:4J8O|rcsb pdb:4JDS|rcsb pdb:4JLG|rcsb pdb:5AYF|go:"GO:0018026"(peptidyl-lysine monomethylation)|rcsb pdb:5EG2|rcsb pdb:5YLT|reactome:R-HSA-3214841 refseq:NP_444513.1|refseq:NP_001287783.1|ensembl:ENSG00000161634(gene)|ensembl:ENST00000293371(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008233"(peptidase activity)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR028130|interpro:IPR043557|mint:P81605|rcsb pdb:2KSG|rcsb pdb:2NDK|rcsb pdb:2YMK|rcsb pdb:6SHK|reactome:R-HSA-6803157 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wqmjJBZrQZT1Uydm62Moi9oGNtQ9606 rogid:M8PkKVWx98nhtd79ods05mqw8Ls9606 rigid:beuhgTdRtGiiLGwhMfEemmJ4iNs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WTS6 uniprotkb:P07355 intact:EBI-1268586|uniprotkb:Q4W5A9|uniprotkb:Q0VAH3|uniprotkb:Q9C0E6|uniprotkb:B5WWL3|ensembl:ENSP00000274031 intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8|ensembl:ENSP00000379342|ensembl:ENSP00000387545|ensembl:ENSP00000411352|ensembl:ENSP00000452858|ensembl:ENSP00000452895|ensembl:ENSP00000452981|ensembl:ENSP00000453694|ensembl:ENSP00000453859|ensembl:ENSP00000503447|ensembl:ENSP00000503757|ensembl:ENSP00000503855|ensembl:ENSP00000504035|ensembl:ENSP00000504164 psi-mi:setd7_human(display_long)|uniprotkb:SETD7(gene name)|psi-mi:SETD7(display_short)|uniprotkb:KIAA1717(gene name synonym)|uniprotkb:SET7(gene name synonym)|uniprotkb:KMT7(gene name synonym)|uniprotkb:SET9(gene name synonym)|uniprotkb:Histone H3-K4 methyltransferase SETD7(gene name synonym)|uniprotkb:SET domain-containing protein 7(gene name synonym)|uniprotkb:SET7/9(gene name synonym)|uniprotkb:Lysine N-methyltransferase 7(gene name synonym) psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484489|imex:IM-26985-279 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_085151.1|dip:DIP-29045N|refseq:NP_001293128.1|ensembl:ENSG00000145391(gene)|ensembl:ENST00000274031(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0045471"(response to ethanol)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0070828"(heterochromatin organization)|interpro:IPR001214(SET)|interpro:IPR003409(MORN motif)|interpro:IPR017155(Histone-lysine N-methyltransferase, SET)|interpro:IPR044436|mint:Q8WTS6|rcsb pdb:1H3I|rcsb pdb:1MT6|rcsb pdb:1MUF|rcsb pdb:1N6A|rcsb pdb:1N6C|rcsb pdb:1O9S|rcsb pdb:1XQH|rcsb pdb:2F69|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:3M53|rcsb pdb:3M54|rcsb pdb:3M55|rcsb pdb:3M56|rcsb pdb:3M57|rcsb pdb:3M58|rcsb pdb:3M59|rcsb pdb:3M5A|rcsb pdb:3OS5|rcsb pdb:3VUZ|rcsb pdb:3VV0|rcsb pdb:4E47|rcsb pdb:4J7F|rcsb pdb:4J7I|rcsb pdb:4J83|rcsb pdb:4J8O|rcsb pdb:4JDS|rcsb pdb:4JLG|rcsb pdb:5AYF|go:"GO:0018026"(peptidyl-lysine monomethylation)|rcsb pdb:5EG2|rcsb pdb:5YLT|reactome:R-HSA-3214841 refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|refseq:XP_016877579.1|refseq:XP_016877580.1|ensembl:ENSG00000182718(gene)|ensembl:ENST00000396024(transcript)|ensembl:ENST00000421017(transcript)|ensembl:ENST00000451270(transcript)|ensembl:ENST00000557906(transcript)|ensembl:ENST00000558558(transcript)|ensembl:ENST00000559818(transcript)|ensembl:ENST00000559956(transcript)|ensembl:ENST00000560468(transcript)|ensembl:ENST00000677968(transcript)|ensembl:ENST00000678061(transcript)|ensembl:ENST00000678450(transcript)|ensembl:ENST00000678870(transcript)|ensembl:ENST00000679109(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0005509"(calcium ion binding)|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|go:"GO:0097066"(response to thyroid hormone) - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wqmjJBZrQZT1Uydm62Moi9oGNtQ9606 rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606 rigid:beuhgTdRtGiiLGwhMfEemmJ4iNs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WTS6 uniprotkb:Q5T1J5 intact:EBI-1268586|uniprotkb:Q4W5A9|uniprotkb:Q0VAH3|uniprotkb:Q9C0E6|uniprotkb:B5WWL3|ensembl:ENSP00000274031 intact:EBI-5325274 psi-mi:setd7_human(display_long)|uniprotkb:SETD7(gene name)|psi-mi:SETD7(display_short)|uniprotkb:KIAA1717(gene name synonym)|uniprotkb:SET7(gene name synonym)|uniprotkb:KMT7(gene name synonym)|uniprotkb:SET9(gene name synonym)|uniprotkb:Histone H3-K4 methyltransferase SETD7(gene name synonym)|uniprotkb:SET domain-containing protein 7(gene name synonym)|uniprotkb:SET7/9(gene name synonym)|uniprotkb:Lysine N-methyltransferase 7(gene name synonym) psi-mi:chch9_human(display_long)|uniprotkb:CHCHD2P9(gene name)|psi-mi:CHCHD2P9(display_short)|uniprotkb:C9orf49(gene name synonym)|uniprotkb:CHCHD9(gene name synonym)|uniprotkb:Coiled-coil-helix-coiled-coil-helix domain-containing 2 pseudogene 9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484489|imex:IM-26985-279 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_085151.1|dip:DIP-29045N|refseq:NP_001293128.1|ensembl:ENSG00000145391(gene)|ensembl:ENST00000274031(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0045471"(response to ethanol)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0070828"(heterochromatin organization)|interpro:IPR001214(SET)|interpro:IPR003409(MORN motif)|interpro:IPR017155(Histone-lysine N-methyltransferase, SET)|interpro:IPR044436|mint:Q8WTS6|rcsb pdb:1H3I|rcsb pdb:1MT6|rcsb pdb:1MUF|rcsb pdb:1N6A|rcsb pdb:1N6C|rcsb pdb:1O9S|rcsb pdb:1XQH|rcsb pdb:2F69|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:3M53|rcsb pdb:3M54|rcsb pdb:3M55|rcsb pdb:3M56|rcsb pdb:3M57|rcsb pdb:3M58|rcsb pdb:3M59|rcsb pdb:3M5A|rcsb pdb:3OS5|rcsb pdb:3VUZ|rcsb pdb:3VV0|rcsb pdb:4E47|rcsb pdb:4J7F|rcsb pdb:4J7I|rcsb pdb:4J83|rcsb pdb:4J8O|rcsb pdb:4JDS|rcsb pdb:4JLG|rcsb pdb:5AYF|go:"GO:0018026"(peptidyl-lysine monomethylation)|rcsb pdb:5EG2|rcsb pdb:5YLT|reactome:R-HSA-3214841 go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|mint:Q5T1J5 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wqmjJBZrQZT1Uydm62Moi9oGNtQ9606 rogid:nxLtnxxMIGeGK2oC3BIhcwkacSs9606 rigid:beuhgTdRtGiiLGwhMfEemmJ4iNs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WTS6 uniprotkb:P05089 intact:EBI-1268586|uniprotkb:Q4W5A9|uniprotkb:Q0VAH3|uniprotkb:Q9C0E6|uniprotkb:B5WWL3|ensembl:ENSP00000274031 intact:EBI-2513844|uniprotkb:Q5JWT6|uniprotkb:Q5JWT5|uniprotkb:Q9BS50|uniprotkb:Q8TE72|uniprotkb:A6NEA0|ensembl:ENSP00000357066 psi-mi:setd7_human(display_long)|uniprotkb:SETD7(gene name)|psi-mi:SETD7(display_short)|uniprotkb:KIAA1717(gene name synonym)|uniprotkb:SET7(gene name synonym)|uniprotkb:KMT7(gene name synonym)|uniprotkb:SET9(gene name synonym)|uniprotkb:Histone H3-K4 methyltransferase SETD7(gene name synonym)|uniprotkb:SET domain-containing protein 7(gene name synonym)|uniprotkb:SET7/9(gene name synonym)|uniprotkb:Lysine N-methyltransferase 7(gene name synonym) psi-mi:argi1_human(display_long)|uniprotkb:ARG1(gene name)|psi-mi:ARG1(display_short)|uniprotkb:Type I arginase(gene name synonym)|uniprotkb:Liver-type arginase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484489|imex:IM-26985-279 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_085151.1|dip:DIP-29045N|refseq:NP_001293128.1|ensembl:ENSG00000145391(gene)|ensembl:ENST00000274031(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0045471"(response to ethanol)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0070828"(heterochromatin organization)|interpro:IPR001214(SET)|interpro:IPR003409(MORN motif)|interpro:IPR017155(Histone-lysine N-methyltransferase, SET)|interpro:IPR044436|mint:Q8WTS6|rcsb pdb:1H3I|rcsb pdb:1MT6|rcsb pdb:1MUF|rcsb pdb:1N6A|rcsb pdb:1N6C|rcsb pdb:1O9S|rcsb pdb:1XQH|rcsb pdb:2F69|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:3M53|rcsb pdb:3M54|rcsb pdb:3M55|rcsb pdb:3M56|rcsb pdb:3M57|rcsb pdb:3M58|rcsb pdb:3M59|rcsb pdb:3M5A|rcsb pdb:3OS5|rcsb pdb:3VUZ|rcsb pdb:3VV0|rcsb pdb:4E47|rcsb pdb:4J7F|rcsb pdb:4J7I|rcsb pdb:4J83|rcsb pdb:4J8O|rcsb pdb:4JDS|rcsb pdb:4JLG|rcsb pdb:5AYF|go:"GO:0018026"(peptidyl-lysine monomethylation)|rcsb pdb:5EG2|rcsb pdb:5YLT|reactome:R-HSA-3214841 refseq:NP_000036.2|refseq:NP_001231367.1|ensembl:ENSG00000118520(gene)|ensembl:ENST00000368087(transcript)|go:"GO:0000050"(urea cycle)|go:"GO:0001889"(liver development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004053"(arginase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006527"(arginine catabolic process)|go:"GO:0007568"(aging)|go:"GO:0009635"(response to herbicide)|go:"GO:0010042"(response to manganese ion)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010963"|go:"GO:0014075"(response to amine)|go:"GO:0019547"(arginine catabolic process to ornithine)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030324"(lung development)|go:"GO:0032964"(collagen biosynthetic process)|go:"GO:0033189"(response to vitamin A)|go:"GO:0033197"(response to vitamin E)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043200"(response to amino acid)|go:"GO:0045087"(innate immune response)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048678"(response to axon injury)|go:"GO:0051597"(response to methylmercury)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070965"(positive regulation of neutrophil mediated killing of fungus)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071377"(cellular response to glucagon stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:2000552"(negative regulation of T-helper 2 cell cytokine production)|interpro:IPR006035(Ureohydrolase)|interpro:IPR014033(Arginase, subgroup)|go:"GO:0060056"(mammary gland involution)|interpro:IPR020855|interpro:IPR023696|mint:P05089|rcsb pdb:1WVA|rcsb pdb:1WVB|rcsb pdb:2AEB|rcsb pdb:2PHA|rcsb pdb:2PHO|rcsb pdb:2PLL|rcsb pdb:2ZAV|rcsb pdb:3DJ8|rcsb pdb:3E6K|rcsb pdb:3E6V|rcsb pdb:3F80|rcsb pdb:3GMZ|rcsb pdb:3GN0|rcsb pdb:3KV2|rcsb pdb:3LP4|rcsb pdb:3LP7|rcsb pdb:3MFV|rcsb pdb:3MFW|rcsb pdb:3MJL|rcsb pdb:3SJT|rcsb pdb:3SKK|rcsb pdb:3TF3|rcsb pdb:3TH7|rcsb pdb:3THE|rcsb pdb:3THH|rcsb pdb:3THJ|rcsb pdb:4FCI|rcsb pdb:4FCK|rcsb pdb:4GSM|rcsb pdb:4GSV|rcsb pdb:4GSZ|rcsb pdb:4GWC|rcsb pdb:4GWD|rcsb pdb:4HWW|rcsb pdb:4HXQ|rcsb pdb:4IE1|rcsb pdb:6Q92|rcsb pdb:6Q9P|rcsb pdb:6QAF|rcsb pdb:6V7C|rcsb pdb:6V7D|rcsb pdb:6V7E|rcsb pdb:6V7F|reactome:R-HSA-6798695|reactome:R-HSA-70635 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wqmjJBZrQZT1Uydm62Moi9oGNtQ9606 rogid:b8HHscDekWZdN1S4OxFTA6rjvn89606 rigid:beuhgTdRtGiiLGwhMfEemmJ4iNs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WTS6 uniprotkb:P60660 intact:EBI-1268586|uniprotkb:Q4W5A9|uniprotkb:Q0VAH3|uniprotkb:Q9C0E6|uniprotkb:B5WWL3|ensembl:ENSP00000274031 intact:EBI-300817|uniprotkb:P16475|uniprotkb:P24572|uniprotkb:P24573|uniprotkb:Q12790|ensembl:ENSP00000446955|ensembl:ENSP00000448101|uniprotkb:Q6IAZ0|uniprotkb:Q6IPY5|uniprotkb:Q561V9 psi-mi:setd7_human(display_long)|uniprotkb:SETD7(gene name)|psi-mi:SETD7(display_short)|uniprotkb:KIAA1717(gene name synonym)|uniprotkb:SET7(gene name synonym)|uniprotkb:KMT7(gene name synonym)|uniprotkb:SET9(gene name synonym)|uniprotkb:Histone H3-K4 methyltransferase SETD7(gene name synonym)|uniprotkb:SET domain-containing protein 7(gene name synonym)|uniprotkb:SET7/9(gene name synonym)|uniprotkb:Lysine N-methyltransferase 7(gene name synonym) psi-mi:myl6_human(display_long)|uniprotkb:MYL6(gene name)|psi-mi:MYL6(display_short)|uniprotkb:Smooth muscle and nonmuscle myosin light chain alkali 6(gene name synonym)|uniprotkb:Myosin light chain alkali 3(gene name synonym)|uniprotkb:Myosin light chain 3(gene name synonym)|uniprotkb:17 kDa myosin light chain(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484489|imex:IM-26985-279 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_085151.1|dip:DIP-29045N|refseq:NP_001293128.1|ensembl:ENSG00000145391(gene)|ensembl:ENST00000274031(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0045471"(response to ethanol)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0070828"(heterochromatin organization)|interpro:IPR001214(SET)|interpro:IPR003409(MORN motif)|interpro:IPR017155(Histone-lysine N-methyltransferase, SET)|interpro:IPR044436|mint:Q8WTS6|rcsb pdb:1H3I|rcsb pdb:1MT6|rcsb pdb:1MUF|rcsb pdb:1N6A|rcsb pdb:1N6C|rcsb pdb:1O9S|rcsb pdb:1XQH|rcsb pdb:2F69|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:3M53|rcsb pdb:3M54|rcsb pdb:3M55|rcsb pdb:3M56|rcsb pdb:3M57|rcsb pdb:3M58|rcsb pdb:3M59|rcsb pdb:3M5A|rcsb pdb:3OS5|rcsb pdb:3VUZ|rcsb pdb:3VV0|rcsb pdb:4E47|rcsb pdb:4J7F|rcsb pdb:4J7I|rcsb pdb:4J83|rcsb pdb:4J8O|rcsb pdb:4JDS|rcsb pdb:4JLG|rcsb pdb:5AYF|go:"GO:0018026"(peptidyl-lysine monomethylation)|rcsb pdb:5EG2|rcsb pdb:5YLT|reactome:R-HSA-3214841 ensembl:ENSG00000092841(gene)|ensembl:ENST00000548293(transcript)|ensembl:ENST00000550697(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0006936"(muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016020"(membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0031982"(vesicle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|mint:P60660|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-445355|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|refseq:NP_066299.2|refseq:NP_524147.2 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wqmjJBZrQZT1Uydm62Moi9oGNtQ9606 rogid:LhE3NUqcuHlOla13C0vjnFZfzy89606 rigid:beuhgTdRtGiiLGwhMfEemmJ4iNs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WTS6 uniprotkb:P10599 intact:EBI-1268586|uniprotkb:Q4W5A9|uniprotkb:Q0VAH3|uniprotkb:Q9C0E6|uniprotkb:B5WWL3|ensembl:ENSP00000274031 intact:EBI-594644|uniprotkb:B1ALW1|uniprotkb:O60744|uniprotkb:Q53X69|uniprotkb:Q96KI3|uniprotkb:Q9UDG5|intact:EBI-1042712|ensembl:ENSP00000363641 psi-mi:setd7_human(display_long)|uniprotkb:SETD7(gene name)|psi-mi:SETD7(display_short)|uniprotkb:KIAA1717(gene name synonym)|uniprotkb:SET7(gene name synonym)|uniprotkb:KMT7(gene name synonym)|uniprotkb:SET9(gene name synonym)|uniprotkb:Histone H3-K4 methyltransferase SETD7(gene name synonym)|uniprotkb:SET domain-containing protein 7(gene name synonym)|uniprotkb:SET7/9(gene name synonym)|uniprotkb:Lysine N-methyltransferase 7(gene name synonym) psi-mi:thio_human(display_long)|uniprotkb:ATL-derived factor(gene name synonym)|uniprotkb:Surface-associated sulphydryl protein(gene name synonym)|uniprotkb:TXN(gene name)|psi-mi:TXN(display_short)|uniprotkb:TRDX(gene name synonym)|uniprotkb:TRX(gene name synonym)|uniprotkb:TRX1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484489|imex:IM-26985-279 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_085151.1|dip:DIP-29045N|refseq:NP_001293128.1|ensembl:ENSG00000145391(gene)|ensembl:ENST00000274031(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0045471"(response to ethanol)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0070828"(heterochromatin organization)|interpro:IPR001214(SET)|interpro:IPR003409(MORN motif)|interpro:IPR017155(Histone-lysine N-methyltransferase, SET)|interpro:IPR044436|mint:Q8WTS6|rcsb pdb:1H3I|rcsb pdb:1MT6|rcsb pdb:1MUF|rcsb pdb:1N6A|rcsb pdb:1N6C|rcsb pdb:1O9S|rcsb pdb:1XQH|rcsb pdb:2F69|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:3M53|rcsb pdb:3M54|rcsb pdb:3M55|rcsb pdb:3M56|rcsb pdb:3M57|rcsb pdb:3M58|rcsb pdb:3M59|rcsb pdb:3M5A|rcsb pdb:3OS5|rcsb pdb:3VUZ|rcsb pdb:3VV0|rcsb pdb:4E47|rcsb pdb:4J7F|rcsb pdb:4J7I|rcsb pdb:4J83|rcsb pdb:4J8O|rcsb pdb:4JDS|rcsb pdb:4JLG|rcsb pdb:5AYF|go:"GO:0018026"(peptidyl-lysine monomethylation)|rcsb pdb:5EG2|rcsb pdb:5YLT|reactome:R-HSA-3214841 refseq:NP_003320.2|refseq:NP_001231867.1|dip:DIP-6129N|ensembl:ENSG00000136810(gene)|ensembl:ENST00000374517(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0004791"(thioredoxin-disulfide reductase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006662"(glycerol ether metabolic process)|go:"GO:0009314"(response to radiation)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0047134"("protein-disulfide reductase (NAD(P)) activity")|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071731"(response to nitric oxide)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|go:"GO:2000170"(positive regulation of peptidyl-cysteine S-nitrosylation)|interpro:IPR005746(Thioredoxin)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017937|interpro:IPR036249|mint:P10599|rcsb pdb:1AIU|rcsb pdb:1AUC|rcsb pdb:1CQG|rcsb pdb:1CQH|rcsb pdb:1ERT|rcsb pdb:1ERU|rcsb pdb:1ERV|rcsb pdb:1ERW|rcsb pdb:1M7T|rcsb pdb:1MDI|rcsb pdb:1MDJ|rcsb pdb:1MDK|rcsb pdb:1TRS|rcsb pdb:1TRU|rcsb pdb:1TRV|rcsb pdb:1TRW|rcsb pdb:1W1C|rcsb pdb:1W1E|rcsb pdb:2HSH|rcsb pdb:2HXK|rcsb pdb:2IFQ|rcsb pdb:2IIY|rcsb pdb:3E3E|rcsb pdb:3KD0|rcsb pdb:3M9J|rcsb pdb:3M9K|rcsb pdb:3QFA|rcsb pdb:3QFB|rcsb pdb:3TRX|rcsb pdb:4LL1|rcsb pdb:4LL4|rcsb pdb:4OO4|rcsb pdb:4OO5|rcsb pdb:4POK|rcsb pdb:4POL|rcsb pdb:4POM|rcsb pdb:4PUF|rcsb pdb:4TRX|rcsb pdb:5DQY|reactome:R-HSA-2559580|reactome:R-HSA-3299685|reactome:R-HSA-499943|reactome:R-HSA-5628897|reactome:R-HSA-5676934|reactome:R-HSA-844456|reactome:R-HSA-9617629|reactome:R-HSA-9660826 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wqmjJBZrQZT1Uydm62Moi9oGNtQ9606 rogid:5u+iJJtwAwAKXljKHnpY8h5uRkQ9606 rigid:beuhgTdRtGiiLGwhMfEemmJ4iNs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WTS6 uniprotkb:P31944 intact:EBI-1268586|uniprotkb:Q4W5A9|uniprotkb:Q0VAH3|uniprotkb:Q9C0E6|uniprotkb:B5WWL3|ensembl:ENSP00000274031 intact:EBI-2510738|ensembl:ENSP00000393417|uniprotkb:O95823|uniprotkb:Q3SYC9 psi-mi:setd7_human(display_long)|uniprotkb:SETD7(gene name)|psi-mi:SETD7(display_short)|uniprotkb:KIAA1717(gene name synonym)|uniprotkb:SET7(gene name synonym)|uniprotkb:KMT7(gene name synonym)|uniprotkb:SET9(gene name synonym)|uniprotkb:Histone H3-K4 methyltransferase SETD7(gene name synonym)|uniprotkb:SET domain-containing protein 7(gene name synonym)|uniprotkb:SET7/9(gene name synonym)|uniprotkb:Lysine N-methyltransferase 7(gene name synonym) psi-mi:caspe_human(display_long)|uniprotkb:CASP14(gene name)|psi-mi:CASP14(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484489|imex:IM-26985-279 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_085151.1|dip:DIP-29045N|refseq:NP_001293128.1|ensembl:ENSG00000145391(gene)|ensembl:ENST00000274031(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0045471"(response to ethanol)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0070828"(heterochromatin organization)|interpro:IPR001214(SET)|interpro:IPR003409(MORN motif)|interpro:IPR017155(Histone-lysine N-methyltransferase, SET)|interpro:IPR044436|mint:Q8WTS6|rcsb pdb:1H3I|rcsb pdb:1MT6|rcsb pdb:1MUF|rcsb pdb:1N6A|rcsb pdb:1N6C|rcsb pdb:1O9S|rcsb pdb:1XQH|rcsb pdb:2F69|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:3M53|rcsb pdb:3M54|rcsb pdb:3M55|rcsb pdb:3M56|rcsb pdb:3M57|rcsb pdb:3M58|rcsb pdb:3M59|rcsb pdb:3M5A|rcsb pdb:3OS5|rcsb pdb:3VUZ|rcsb pdb:3VV0|rcsb pdb:4E47|rcsb pdb:4J7F|rcsb pdb:4J7I|rcsb pdb:4J83|rcsb pdb:4J8O|rcsb pdb:4JDS|rcsb pdb:4JLG|rcsb pdb:5AYF|go:"GO:0018026"(peptidyl-lysine monomethylation)|rcsb pdb:5EG2|rcsb pdb:5YLT|reactome:R-HSA-3214841 interpro:IPR002398(Peptidase C14, caspase precursor p45)|interpro:IPR015917(Peptidase C14, caspase precursor p45, core)|interpro:IPR029030|interpro:IPR033139|interpro:IPR033174|mint:P31944|reactome:R-HSA-6809371|ensembl:ENSG00000105141(gene)|ensembl:ENST00000427043(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0031424"(keratinization)|go:"GO:0045095"(keratin filament)|go:"GO:0070268"(cornification)|go:"GO:0097200"(cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR001309(Peptidase C14, ICE, catalytic subunit p20)|interpro:IPR002138(Peptidase C14, caspase non-catalytic subunit p10)|refseq:NP_036246.1 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wqmjJBZrQZT1Uydm62Moi9oGNtQ9606 rogid:e8QPsuebgXeKJEuMm/KU0WAOs3k9606 rigid:beuhgTdRtGiiLGwhMfEemmJ4iNs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WTS6 uniprotkb:Q16777 intact:EBI-1268586|uniprotkb:Q4W5A9|uniprotkb:Q0VAH3|uniprotkb:Q9C0E6|uniprotkb:B5WWL3|ensembl:ENSP00000274031 intact:EBI-5325566|ensembl:ENSP00000332194|uniprotkb:Q6DRA7|uniprotkb:Q8IUE5 psi-mi:setd7_human(display_long)|uniprotkb:SETD7(gene name)|psi-mi:SETD7(display_short)|uniprotkb:KIAA1717(gene name synonym)|uniprotkb:SET7(gene name synonym)|uniprotkb:KMT7(gene name synonym)|uniprotkb:SET9(gene name synonym)|uniprotkb:Histone H3-K4 methyltransferase SETD7(gene name synonym)|uniprotkb:SET domain-containing protein 7(gene name synonym)|uniprotkb:SET7/9(gene name synonym)|uniprotkb:Lysine N-methyltransferase 7(gene name synonym) psi-mi:h2a2c_human(display_long)|uniprotkb:H2AC20(gene name)|psi-mi:H2AC20(display_short)|uniprotkb:H2A-clustered histone 20(gene name synonym)|uniprotkb:H2AFQ(gene name synonym)|uniprotkb:HIST2H2AC(gene name synonym)|uniprotkb:Histone H2A-GL101(gene name synonym)|uniprotkb:Histone H2A/q(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484489|imex:IM-26985-279 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_085151.1|dip:DIP-29045N|refseq:NP_001293128.1|ensembl:ENSG00000145391(gene)|ensembl:ENST00000274031(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0045471"(response to ethanol)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0070828"(heterochromatin organization)|interpro:IPR001214(SET)|interpro:IPR003409(MORN motif)|interpro:IPR017155(Histone-lysine N-methyltransferase, SET)|interpro:IPR044436|mint:Q8WTS6|rcsb pdb:1H3I|rcsb pdb:1MT6|rcsb pdb:1MUF|rcsb pdb:1N6A|rcsb pdb:1N6C|rcsb pdb:1O9S|rcsb pdb:1XQH|rcsb pdb:2F69|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:3M53|rcsb pdb:3M54|rcsb pdb:3M55|rcsb pdb:3M56|rcsb pdb:3M57|rcsb pdb:3M58|rcsb pdb:3M59|rcsb pdb:3M5A|rcsb pdb:3OS5|rcsb pdb:3VUZ|rcsb pdb:3VV0|rcsb pdb:4E47|rcsb pdb:4J7F|rcsb pdb:4J7I|rcsb pdb:4J83|rcsb pdb:4J8O|rcsb pdb:4JDS|rcsb pdb:4JLG|rcsb pdb:5AYF|go:"GO:0018026"(peptidyl-lysine monomethylation)|rcsb pdb:5EG2|rcsb pdb:5YLT|reactome:R-HSA-3214841 reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-5689603|ensembl:ENSG00000184260(gene)|ensembl:ENST00000331380(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:Q16777|rcsb pdb:6Y5E|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|refseq:NP_003508.1 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wqmjJBZrQZT1Uydm62Moi9oGNtQ9606 rogid:Wejrpp9wK3GvA4ahJDVyEH+cwlQ9606 rigid:beuhgTdRtGiiLGwhMfEemmJ4iNs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WTS6 uniprotkb:P16403 intact:EBI-1268586|uniprotkb:Q4W5A9|uniprotkb:Q0VAH3|uniprotkb:Q9C0E6|uniprotkb:B5WWL3|ensembl:ENSP00000274031 intact:EBI-358372|ensembl:ENSP00000339566|uniprotkb:A8K4I2 psi-mi:setd7_human(display_long)|uniprotkb:SETD7(gene name)|psi-mi:SETD7(display_short)|uniprotkb:KIAA1717(gene name synonym)|uniprotkb:SET7(gene name synonym)|uniprotkb:KMT7(gene name synonym)|uniprotkb:SET9(gene name synonym)|uniprotkb:Histone H3-K4 methyltransferase SETD7(gene name synonym)|uniprotkb:SET domain-containing protein 7(gene name synonym)|uniprotkb:SET7/9(gene name synonym)|uniprotkb:Lysine N-methyltransferase 7(gene name synonym) psi-mi:h12_human(display_long)|uniprotkb:H1-2(gene name)|psi-mi:H1-2(display_short)|uniprotkb:H1F2(gene name synonym)|uniprotkb:HIST1H1C(gene name synonym)|uniprotkb:Histone H1c(gene name synonym)|uniprotkb:Histone H1d(gene name synonym)|uniprotkb:Histone H1s-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484489|imex:IM-26985-279 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_085151.1|dip:DIP-29045N|refseq:NP_001293128.1|ensembl:ENSG00000145391(gene)|ensembl:ENST00000274031(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0045471"(response to ethanol)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0070828"(heterochromatin organization)|interpro:IPR001214(SET)|interpro:IPR003409(MORN motif)|interpro:IPR017155(Histone-lysine N-methyltransferase, SET)|interpro:IPR044436|mint:Q8WTS6|rcsb pdb:1H3I|rcsb pdb:1MT6|rcsb pdb:1MUF|rcsb pdb:1N6A|rcsb pdb:1N6C|rcsb pdb:1O9S|rcsb pdb:1XQH|rcsb pdb:2F69|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:3M53|rcsb pdb:3M54|rcsb pdb:3M55|rcsb pdb:3M56|rcsb pdb:3M57|rcsb pdb:3M58|rcsb pdb:3M59|rcsb pdb:3M5A|rcsb pdb:3OS5|rcsb pdb:3VUZ|rcsb pdb:3VV0|rcsb pdb:4E47|rcsb pdb:4J7F|rcsb pdb:4J7I|rcsb pdb:4J83|rcsb pdb:4J8O|rcsb pdb:4JDS|rcsb pdb:4JLG|rcsb pdb:5AYF|go:"GO:0018026"(peptidyl-lysine monomethylation)|rcsb pdb:5EG2|rcsb pdb:5YLT|reactome:R-HSA-3214841 refseq:NP_005310.1|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P16403|reactome:R-HSA-140342|reactome:R-HSA-2559584|ensembl:ENSG00000187837(gene)|ensembl:ENST00000343677(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|dip:DIP-36359N - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wqmjJBZrQZT1Uydm62Moi9oGNtQ9606 rogid:eRT5bTyBJUg6nRANMRYZekT4N+g9606 rigid:beuhgTdRtGiiLGwhMfEemmJ4iNs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WTS6 uniprotkb:O14950 intact:EBI-1268586|uniprotkb:Q4W5A9|uniprotkb:Q0VAH3|uniprotkb:Q9C0E6|uniprotkb:B5WWL3|ensembl:ENSP00000274031 intact:EBI-1642165|uniprotkb:D3DUH6|intact:EBI-2826593|uniprotkb:Q7Z5Z4|uniprotkb:Q13182|ensembl:ENSP00000237500|ensembl:ENSP00000383037|ensembl:ENSP00000463559|ensembl:ENSP00000464464|ensembl:ENSP00000496809 psi-mi:setd7_human(display_long)|uniprotkb:SETD7(gene name)|psi-mi:SETD7(display_short)|uniprotkb:KIAA1717(gene name synonym)|uniprotkb:SET7(gene name synonym)|uniprotkb:KMT7(gene name synonym)|uniprotkb:SET9(gene name synonym)|uniprotkb:Histone H3-K4 methyltransferase SETD7(gene name synonym)|uniprotkb:SET domain-containing protein 7(gene name synonym)|uniprotkb:SET7/9(gene name synonym)|uniprotkb:Lysine N-methyltransferase 7(gene name synonym) psi-mi:ml12b_human(display_long)|uniprotkb:MYL12B(gene name)|psi-mi:MYL12B(display_short)|uniprotkb:MRLC2(gene name synonym)|uniprotkb:Myosin regulatory light chain 2-B, smooth muscle isoform(gene name synonym)|uniprotkb:MLC-2A(gene name synonym)|uniprotkb:SHUJUN-1(gene name synonym)|uniprotkb:MYLC2B(gene name synonym)|uniprotkb:Myosin regulatory light chain MRLC2(gene name synonym)|uniprotkb:Myosin regulatory light chain 20 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484489|imex:IM-26985-279 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_085151.1|dip:DIP-29045N|refseq:NP_001293128.1|ensembl:ENSG00000145391(gene)|ensembl:ENST00000274031(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0045471"(response to ethanol)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0070828"(heterochromatin organization)|interpro:IPR001214(SET)|interpro:IPR003409(MORN motif)|interpro:IPR017155(Histone-lysine N-methyltransferase, SET)|interpro:IPR044436|mint:Q8WTS6|rcsb pdb:1H3I|rcsb pdb:1MT6|rcsb pdb:1MUF|rcsb pdb:1N6A|rcsb pdb:1N6C|rcsb pdb:1O9S|rcsb pdb:1XQH|rcsb pdb:2F69|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:3M53|rcsb pdb:3M54|rcsb pdb:3M55|rcsb pdb:3M56|rcsb pdb:3M57|rcsb pdb:3M58|rcsb pdb:3M59|rcsb pdb:3M5A|rcsb pdb:3OS5|rcsb pdb:3VUZ|rcsb pdb:3VV0|rcsb pdb:4E47|rcsb pdb:4J7F|rcsb pdb:4J7I|rcsb pdb:4J83|rcsb pdb:4J8O|rcsb pdb:4JDS|rcsb pdb:4JLG|rcsb pdb:5AYF|go:"GO:0018026"(peptidyl-lysine monomethylation)|rcsb pdb:5EG2|rcsb pdb:5YLT|reactome:R-HSA-3214841 refseq:NP_001138416.1|refseq:NP_001138417.1|refseq:NP_291024.1|refseq:NP_001289978.1|ensembl:ENSG00000118680(gene)|ensembl:ENST00000237500(transcript)|ensembl:ENST00000400175(transcript)|ensembl:ENST00000581193(transcript)|ensembl:ENST00000584539(transcript)|ensembl:ENST00000648965(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016460"(myosin II complex)|go:"GO:0030018"(Z disc)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR015070(Region of unknown function DUF1880)|interpro:IPR018247|mint:O14950|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-445355|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123 - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wqmjJBZrQZT1Uydm62Moi9oGNtQ9606 rogid:5jOP3J5TW0eU9zwalQ2S4Oist4k9606 rigid:beuhgTdRtGiiLGwhMfEemmJ4iNs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8WTS6 uniprotkb:P47914 intact:EBI-1268586|uniprotkb:Q4W5A9|uniprotkb:Q0VAH3|uniprotkb:Q9C0E6|uniprotkb:B5WWL3|ensembl:ENSP00000274031 intact:EBI-714039|uniprotkb:Q6IPY3|ensembl:ENSP00000418346|ensembl:ENSP00000418868|ensembl:ENSP00000420673|ensembl:ENSP00000294189|ensembl:ENSP00000417048|ensembl:ENSP00000418153|uniprotkb:B2R4M8|uniprotkb:A8K0H3 psi-mi:setd7_human(display_long)|uniprotkb:SETD7(gene name)|psi-mi:SETD7(display_short)|uniprotkb:KIAA1717(gene name synonym)|uniprotkb:SET7(gene name synonym)|uniprotkb:KMT7(gene name synonym)|uniprotkb:SET9(gene name synonym)|uniprotkb:Histone H3-K4 methyltransferase SETD7(gene name synonym)|uniprotkb:SET domain-containing protein 7(gene name synonym)|uniprotkb:SET7/9(gene name synonym)|uniprotkb:Lysine N-methyltransferase 7(gene name synonym) psi-mi:rl29_human(display_long)|uniprotkb:Cell surface heparin-binding protein HIP(gene name synonym)|uniprotkb:RPL29(gene name)|psi-mi:RPL29(display_short)|uniprotkb:Large ribosomal subunit protein eL29(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484489|imex:IM-26985-279 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_085151.1|dip:DIP-29045N|refseq:NP_001293128.1|ensembl:ENSG00000145391(gene)|ensembl:ENST00000274031(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0045471"(response to ethanol)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051570"(regulation of histone H3-K9 methylation)|go:"GO:0070828"(heterochromatin organization)|interpro:IPR001214(SET)|interpro:IPR003409(MORN motif)|interpro:IPR017155(Histone-lysine N-methyltransferase, SET)|interpro:IPR044436|mint:Q8WTS6|rcsb pdb:1H3I|rcsb pdb:1MT6|rcsb pdb:1MUF|rcsb pdb:1N6A|rcsb pdb:1N6C|rcsb pdb:1O9S|rcsb pdb:1XQH|rcsb pdb:2F69|rcsb pdb:3CBM|rcsb pdb:3CBO|rcsb pdb:3CBP|rcsb pdb:3M53|rcsb pdb:3M54|rcsb pdb:3M55|rcsb pdb:3M56|rcsb pdb:3M57|rcsb pdb:3M58|rcsb pdb:3M59|rcsb pdb:3M5A|rcsb pdb:3OS5|rcsb pdb:3VUZ|rcsb pdb:3VV0|rcsb pdb:4E47|rcsb pdb:4J7F|rcsb pdb:4J7I|rcsb pdb:4J83|rcsb pdb:4J8O|rcsb pdb:4JDS|rcsb pdb:4JLG|rcsb pdb:5AYF|go:"GO:0018026"(peptidyl-lysine monomethylation)|rcsb pdb:5EG2|rcsb pdb:5YLT|reactome:R-HSA-3214841 ensembl:ENST00000294189(transcript)|ensembl:ENST00000466397(transcript)|ensembl:ENST00000475248(transcript)|ensembl:ENST00000479017(transcript)|ensembl:ENST00000492277(transcript)|ensembl:ENST00000495383(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0007566"(embryo implantation)|go:"GO:0008201"(heparin binding)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR002673(Ribosomal protein L29e)|mint:P47914|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|ensembl:ENSG00000162244(gene)|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_000983.1|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339 - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wqmjJBZrQZT1Uydm62Moi9oGNtQ9606 rogid:XZUSMDDzycAi6QEXYbljXaeVg0U9606 rigid:beuhgTdRtGiiLGwhMfEemmJ4iNs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VUG0 uniprotkb:Q86V15 intact:EBI-12025260|ensembl:ENSP00000355109|ensembl:ENSP00000380353|uniprotkb:A7MD09|uniprotkb:Q9HCF5 intact:EBI-9057702|uniprotkb:Q9NXC6|uniprotkb:Q6ZNM8|uniprotkb:Q8WX49|uniprotkb:Q9BT16|uniprotkb:Q5T9S1|uniprotkb:Q2EN02|uniprotkb:Q8WX50|uniprotkb:Q078S9|intact:EBI-28987584|ensembl:ENSP00000366221 psi-mi:smbt2_human(display_long)|uniprotkb:SFMBT2(gene name)|psi-mi:SFMBT2(display_short)|uniprotkb:KIAA1617(gene name synonym) psi-mi:casz1_human(display_long)|uniprotkb:CASZ1(gene name)|psi-mi:CASZ1(display_short)|uniprotkb:CST(gene name synonym)|uniprotkb:Castor-related protein(gene name synonym)|uniprotkb:Putative survival-related protein(gene name synonym)|uniprotkb:SRG(gene name synonym)|uniprotkb:ZNF693(gene name synonym)|uniprotkb:Zinc finger protein 693(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484723|imex:IM-26985-281 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000198879(gene)|ensembl:ENST00000361972(transcript)|ensembl:ENST00000397167(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016235"(aggresome)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0042393"(histone binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR037604|interpro:IPR038348|mint:Q5VUG0|rcsb pdb:1WJR|refseq:NP_001018049.1|refseq:NP_001025051.1|refseq:XP_011517913.1|refseq:XP_016871955.1 refseq:NP_001073312.1|refseq:NP_060236.3|ensembl:ENST00000344008|ensembl:ENSP00000339445|ensembl:ENSP00000366221|ensembl:ENSG00000130940(gene)|ensembl:ENST00000377022(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045664"(regulation of neuron differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR040373|mint:Q86V15|go:"GO:0045893"(positive regulation of transcription, DNA-templated) - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ekByFM3jqM1sgzg6rpUmrMmiBPc9606 rogid:sLhUlrOfukl0V8xw3B6CO9D/BSQ9606 rigid:pDjT+SQUh4Paa6eGXaMjWCXa7AM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VUG0 uniprotkb:Q9UBQ7 intact:EBI-12025260|ensembl:ENSP00000355109|ensembl:ENSP00000380353|uniprotkb:A7MD09|uniprotkb:Q9HCF5 intact:EBI-372445|uniprotkb:Q9H3E9|uniprotkb:Q9UKX1|ensembl:ENSP00000313432|uniprotkb:Q5T945|uniprotkb:Q9H636 psi-mi:smbt2_human(display_long)|uniprotkb:SFMBT2(gene name)|psi-mi:SFMBT2(display_short)|uniprotkb:KIAA1617(gene name synonym) psi-mi:grhpr_human(display_long)|uniprotkb:MSTP035(orf name)|uniprotkb:GRHPR(gene name)|psi-mi:GRHPR(display_short)|uniprotkb:GLXR(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484723|imex:IM-26985-281 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000198879(gene)|ensembl:ENST00000361972(transcript)|ensembl:ENST00000397167(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016235"(aggresome)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0042393"(histone binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR037604|interpro:IPR038348|mint:Q5VUG0|rcsb pdb:1WJR|refseq:NP_001018049.1|refseq:NP_001025051.1|refseq:XP_011517913.1|refseq:XP_016871955.1 refseq:NP_036335.1|go:"GO:0043648"(dicarboxylic acid metabolic process)|go:"GO:0046487"(glyoxylate metabolic process)|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070402"(NADPH binding)|go:"GO:1902494"(catalytic complex)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029753|interpro:IPR036291|mint:Q9UBQ7|rcsb pdb:2GCG|rcsb pdb:2H1S|rcsb pdb:2Q50|rcsb pdb:2WWR|reactome:R-HSA-389661|ensembl:ENSG00000137106(gene)|ensembl:ENST00000318158(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0007588"(excretion)|go:"GO:0008465"(glycerate dehydrogenase activity)|go:"GO:0016618"(hydroxypyruvate reductase activity)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0030267"("glyoxylate reductase (NADP+) activity")|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0042803"(protein homodimerization activity) - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ekByFM3jqM1sgzg6rpUmrMmiBPc9606 rogid:qPHrh5I5wHI5MWba4zncz26cUnQ9606 rigid:pDjT+SQUh4Paa6eGXaMjWCXa7AM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VUG0 uniprotkb:P81605 intact:EBI-12025260|ensembl:ENSP00000355109|ensembl:ENSP00000380353|uniprotkb:A7MD09|uniprotkb:Q9HCF5 intact:EBI-395625|uniprotkb:P58461|uniprotkb:A5JHP2|uniprotkb:A5JHP3|uniprotkb:Q53YJ2|ensembl:ENSP00000293371 psi-mi:smbt2_human(display_long)|uniprotkb:SFMBT2(gene name)|psi-mi:SFMBT2(display_short)|uniprotkb:KIAA1617(gene name synonym) psi-mi:dcd_human(display_long)|uniprotkb:AIDD(gene name synonym)|uniprotkb:DSEP(gene name synonym)|uniprotkb:Preproteolysin(gene name synonym)|uniprotkb:DCD(gene name)|psi-mi:DCD(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484723|imex:IM-26985-281 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000198879(gene)|ensembl:ENST00000361972(transcript)|ensembl:ENST00000397167(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016235"(aggresome)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0042393"(histone binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR037604|interpro:IPR038348|mint:Q5VUG0|rcsb pdb:1WJR|refseq:NP_001018049.1|refseq:NP_001025051.1|refseq:XP_011517913.1|refseq:XP_016871955.1 refseq:NP_444513.1|refseq:NP_001287783.1|ensembl:ENSG00000161634(gene)|ensembl:ENST00000293371(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008233"(peptidase activity)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR028130|interpro:IPR043557|mint:P81605|rcsb pdb:2KSG|rcsb pdb:2NDK|rcsb pdb:2YMK|rcsb pdb:6SHK|reactome:R-HSA-6803157 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ekByFM3jqM1sgzg6rpUmrMmiBPc9606 rogid:M8PkKVWx98nhtd79ods05mqw8Ls9606 rigid:pDjT+SQUh4Paa6eGXaMjWCXa7AM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VUG0 uniprotkb:Q16637 intact:EBI-12025260|ensembl:ENSP00000355109|ensembl:ENSP00000380353|uniprotkb:A7MD09|uniprotkb:Q9HCF5 intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421 psi-mi:smbt2_human(display_long)|uniprotkb:SFMBT2(gene name)|psi-mi:SFMBT2(display_short)|uniprotkb:KIAA1617(gene name synonym) psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484723|imex:IM-26985-281 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000198879(gene)|ensembl:ENST00000361972(transcript)|ensembl:ENST00000397167(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016235"(aggresome)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0042393"(histone binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR037604|interpro:IPR038348|mint:Q5VUG0|rcsb pdb:1WJR|refseq:NP_001018049.1|refseq:NP_001025051.1|refseq:XP_011517913.1|refseq:XP_016871955.1 refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ekByFM3jqM1sgzg6rpUmrMmiBPc9606 rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606 rigid:pDjT+SQUh4Paa6eGXaMjWCXa7AM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5VUG0 uniprotkb:Q6SPF0 intact:EBI-12025260|ensembl:ENSP00000355109|ensembl:ENSP00000380353|uniprotkb:A7MD09|uniprotkb:Q9HCF5 intact:EBI-8833536|uniprotkb:Q96IM4|uniprotkb:Q6PIS7|uniprotkb:Q6P0R3 psi-mi:smbt2_human(display_long)|uniprotkb:SFMBT2(gene name)|psi-mi:SFMBT2(display_short)|uniprotkb:KIAA1617(gene name synonym) psi-mi:samd1_human(display_long)|uniprotkb:SAMD1(gene name)|psi-mi:SAMD1(display_short)|uniprotkb:Atherin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484723|imex:IM-26985-281 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000198879(gene)|ensembl:ENST00000361972(transcript)|ensembl:ENST00000397167(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016235"(aggresome)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0042393"(histone binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR037604|interpro:IPR038348|mint:Q5VUG0|rcsb pdb:1WJR|refseq:NP_001018049.1|refseq:NP_001025051.1|refseq:XP_011517913.1|refseq:XP_016871955.1 mint:Q6SPF0|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_612361.1|go:"GO:0005737"(cytoplasm)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|rcsb pdb:6LUI|rcsb pdb:6LUJ|rcsb pdb:6LUK|go:"GO:0003682"(chromatin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus) - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ekByFM3jqM1sgzg6rpUmrMmiBPc9606 rogid:Cav/ZfHiZJ1xCBI6jAYrzv+CmZ49606 rigid:pDjT+SQUh4Paa6eGXaMjWCXa7AM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UHJ3 uniprotkb:P22532 intact:EBI-747398|uniprotkb:Q96C73|uniprotkb:Q9Y4Q9|uniprotkb:Q402F7|ensembl:ENSP00000378235 intact:EBI-2267183|uniprotkb:A8K5K2|uniprotkb:Q5T523|uniprotkb:Q96RM3|uniprotkb:A4QN03|uniprotkb:D3DV33|ensembl:ENSP00000353542|ensembl:ENSP00000357745|ensembl:ENSP00000357746|ensembl:ENSP00000357747 psi-mi:smbt1_human(display_long)|uniprotkb:Renal ubiquitous protein 1(gene name synonym)|uniprotkb:SFMBT1(gene name)|psi-mi:SFMBT1(display_short)|uniprotkb:RU1(gene name synonym) psi-mi:spr2d_human(display_long)|uniprotkb:SPRR2D(gene name)|psi-mi:SPRR2D(display_short)|uniprotkb:Small proline-rich protein II(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484663|imex:IM-26985-507 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006713266.1|refseq:XP_006713267.1|refseq:NP_057413.2|refseq:XP_011532126.1|refseq:XP_011532127.1|refseq:XP_005265278.1|ensembl:ENSG00000163935(gene)|ensembl:ENST00000394752(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048635"(negative regulation of muscle organ development)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR037604|interpro:IPR038348|mint:Q9UHJ3 refseq:XP_016857664.1|refseq:NP_008876.3|ensembl:ENSG00000163216(gene)|ensembl:ENST00000360379(transcript)|ensembl:ENST00000368756(transcript)|ensembl:ENST00000368757(transcript)|ensembl:ENST00000368758(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0031424"(keratinization)|interpro:IPR029142|mint:P22532|reactome:R-HSA-6809371 - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:vh/dDMpcLQEo57Wcjnggufh6HRk9606 rogid:lenGTh/4TMFWnOff3clJuq6/IeU9606 rigid:0zUcpcUMAoZNa4lAzH7QV8gfQRo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UHJ3 uniprotkb:O00570 intact:EBI-747398|uniprotkb:Q96C73|uniprotkb:Q9Y4Q9|uniprotkb:Q402F7|ensembl:ENSP00000378235 intact:EBI-2935583|ensembl:ENSP00000330218|uniprotkb:Q5W0Q1 psi-mi:smbt1_human(display_long)|uniprotkb:Renal ubiquitous protein 1(gene name synonym)|uniprotkb:SFMBT1(gene name)|psi-mi:SFMBT1(display_short)|uniprotkb:RU1(gene name synonym) psi-mi:sox1_human(display_long)|uniprotkb:SOX1(gene name)|psi-mi:SOX1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484663|imex:IM-26985-507 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006713266.1|refseq:XP_006713267.1|refseq:NP_057413.2|refseq:XP_011532126.1|refseq:XP_011532127.1|refseq:XP_005265278.1|ensembl:ENSG00000163935(gene)|ensembl:ENST00000394752(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048635"(negative regulation of muscle organ development)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR037604|interpro:IPR038348|mint:Q9UHJ3 ensembl:ENSG00000182968(gene)|ensembl:ENST00000330949(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0021521"(ventral spinal cord interneuron specification)|go:"GO:0021884"(forebrain neuron development)|go:"GO:0030154"(cell differentiation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:1904936"(interneuron migration)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR022097|interpro:IPR031268|interpro:IPR036910|mint:O00570|go:"GO:0048713"(regulation of oligodendrocyte differentiation)|refseq:NP_005977.2 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:vh/dDMpcLQEo57Wcjnggufh6HRk9606 rogid:SICOjAD/I9cpyMAjYTlAd4Pf1yQ9606 rigid:0zUcpcUMAoZNa4lAzH7QV8gfQRo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UHJ3 uniprotkb:P68363 intact:EBI-747398|uniprotkb:Q96C73|uniprotkb:Q9Y4Q9|uniprotkb:Q402F7|ensembl:ENSP00000378235 intact:EBI-487083|intact:EBI-1384226|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:Q27I68|ensembl:ENSP00000336799|uniprotkb:Q8WU19 psi-mi:smbt1_human(display_long)|uniprotkb:Renal ubiquitous protein 1(gene name synonym)|uniprotkb:SFMBT1(gene name)|psi-mi:SFMBT1(display_short)|uniprotkb:RU1(gene name synonym) psi-mi:tba1b_human(display_long)|uniprotkb:TUBA1B(gene name)|psi-mi:TUBA1B(display_short)|uniprotkb:Tubulin alpha-ubiquitous chain(gene name synonym)|uniprotkb:Alpha-tubulin ubiquitous(gene name synonym)|uniprotkb:Tubulin K-alpha-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484663|imex:IM-26985-507 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006713266.1|refseq:XP_006713267.1|refseq:NP_057413.2|refseq:XP_011532126.1|refseq:XP_011532127.1|refseq:XP_005265278.1|ensembl:ENSG00000163935(gene)|ensembl:ENST00000394752(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048635"(negative regulation of muscle organ development)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR037604|interpro:IPR038348|mint:Q9UHJ3 refseq:NP_006073.2|ensembl:ENSG00000123416(gene)|ensembl:ENST00000336023(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-983189|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|go:"GO:0045121"(membrane raft)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68363|rcsb pdb:2E4H|rcsb pdb:5IJ0|rcsb pdb:5IJ9|rcsb pdb:5N5N|rcsb pdb:6E7B|rcsb pdb:6E7C|rcsb pdb:6I2I|go:"GO:0051301"(cell division)|rcsb pdb:6J4V|rcsb pdb:6J8O|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|rcsb pdb:6S8L|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9013407|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-2132295|reactome:R-HSA-9668328 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:vh/dDMpcLQEo57Wcjnggufh6HRk9606 rogid:D4YpuLCXl/S+53qV7P7sF81aARY9606 rigid:0zUcpcUMAoZNa4lAzH7QV8gfQRo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UHJ3 uniprotkb:Q9NZT1 intact:EBI-747398|uniprotkb:Q96C73|uniprotkb:Q9Y4Q9|uniprotkb:Q402F7|ensembl:ENSP00000378235 intact:EBI-1051681|uniprotkb:Q8IXU8|uniprotkb:Q5SQI3|ensembl:ENSP00000369689 psi-mi:smbt1_human(display_long)|uniprotkb:Renal ubiquitous protein 1(gene name synonym)|uniprotkb:SFMBT1(gene name)|psi-mi:SFMBT1(display_short)|uniprotkb:RU1(gene name synonym) psi-mi:call5_human(display_long)|uniprotkb:Calmodulin-like skin protein(gene name synonym)|uniprotkb:CALML5(gene name)|psi-mi:CALML5(display_short)|uniprotkb:CLSP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484663|imex:IM-26985-507 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006713266.1|refseq:XP_006713267.1|refseq:NP_057413.2|refseq:XP_011532126.1|refseq:XP_011532127.1|refseq:XP_005265278.1|ensembl:ENSG00000163935(gene)|ensembl:ENST00000394752(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048635"(negative regulation of muscle organ development)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR037604|interpro:IPR038348|mint:Q9UHJ3 refseq:NP_059118.2|ensembl:ENST00000380332(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0007165"(signal transduction)|go:"GO:0008544"(epidermis development)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q9NZT1|rcsb pdb:2B1U|reactome:R-HSA-6798695|ensembl:ENSG00000178372(gene) - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:vh/dDMpcLQEo57Wcjnggufh6HRk9606 rogid:uPD/avsoqpiogqHCK5TGJQwvCX89606 rigid:0zUcpcUMAoZNa4lAzH7QV8gfQRo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UHJ3 uniprotkb:Q92618 intact:EBI-747398|uniprotkb:Q96C73|uniprotkb:Q9Y4Q9|uniprotkb:Q402F7|ensembl:ENSP00000378235 intact:EBI-2799490|intact:EBI-28975450|ensembl:ENSP00000394757 psi-mi:smbt1_human(display_long)|uniprotkb:Renal ubiquitous protein 1(gene name synonym)|uniprotkb:SFMBT1(gene name)|psi-mi:SFMBT1(display_short)|uniprotkb:RU1(gene name synonym) psi-mi:zn516_human(display_long)|uniprotkb:KIAA0222(gene name synonym)|uniprotkb:ZNF516(gene name)|psi-mi:ZNF516(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484663|imex:IM-26985-507 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006713266.1|refseq:XP_006713267.1|refseq:NP_057413.2|refseq:XP_011532126.1|refseq:XP_011532127.1|refseq:XP_005265278.1|ensembl:ENSG00000163935(gene)|ensembl:ENST00000394752(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048635"(negative regulation of muscle organ development)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR037604|interpro:IPR038348|mint:Q9UHJ3 ensembl:ENSP00000394757|refseq:XP_011524571.1|refseq:XP_011524572.1|refseq:XP_011524573.1|refseq:XP_011524574.1|refseq:XP_011524575.1|refseq:XP_011524576.1|refseq:XP_011524577.1|refseq:NP_055458.1|ensembl:ENSG00000101493(gene)|ensembl:ENST00000443185(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009409"(response to cold)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0050873"(brown fat cell differentiation)|go:"GO:0060612"(adipose tissue development)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q92618|refseq:XP_016881586.1 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:vh/dDMpcLQEo57Wcjnggufh6HRk9606 rogid:L9yQp1u4G/AN1L79Bg8odnkiPi89606 rigid:0zUcpcUMAoZNa4lAzH7QV8gfQRo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UHJ3 uniprotkb:P04083 intact:EBI-747398|uniprotkb:Q96C73|uniprotkb:Q9Y4Q9|uniprotkb:Q402F7|ensembl:ENSP00000378235 intact:EBI-354007|ensembl:ENSP00000257497|ensembl:ENSP00000366109|uniprotkb:B5BU38 psi-mi:smbt1_human(display_long)|uniprotkb:Renal ubiquitous protein 1(gene name synonym)|uniprotkb:SFMBT1(gene name)|psi-mi:SFMBT1(display_short)|uniprotkb:RU1(gene name synonym) psi-mi:anxa1_human(display_long)|uniprotkb:ANXA1(gene name)|psi-mi:ANXA1(display_short)|uniprotkb:ANX1(gene name synonym)|uniprotkb:LPC1(gene name synonym)|uniprotkb:Annexin-1(gene name synonym)|uniprotkb:Annexin I(gene name synonym)|uniprotkb:Lipocortin I(gene name synonym)|uniprotkb:Calpactin II(gene name synonym)|uniprotkb:Chromobindin-9(gene name synonym)|uniprotkb:p35(gene name synonym)|uniprotkb:Phospholipase A2 inhibitory protein(gene name synonym)|uniprotkb:Calpactin-2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484663|imex:IM-26985-507 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006713266.1|refseq:XP_006713267.1|refseq:NP_057413.2|refseq:XP_011532126.1|refseq:XP_011532127.1|refseq:XP_005265278.1|ensembl:ENSG00000163935(gene)|ensembl:ENST00000394752(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048635"(negative regulation of muscle organ development)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR037604|interpro:IPR038348|mint:Q9UHJ3 refseq:NP_000691.1|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030073"(insulin secretion)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030850"(prostate gland development)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0031313"(extrinsic component of endosome membrane)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0031514"(motile cilium)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032355"(response to estradiol)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0032652"(regulation of interleukin-1 production)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033031"(positive regulation of neutrophil apoptotic process)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036121"(double-stranded DNA helicase activity)|go:"GO:0042063"(gliogenesis)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042493"|go:"GO:0042629"(mast cell granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045087"(innate immune response)|go:"GO:0045627"(positive regulation of T-helper 1 cell differentiation)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0045920"(negative regulation of exocytosis)|go:"GO:0046632"(alpha-beta T cell differentiation)|ensembl:ENSG00000135046(gene)|ensembl:ENST00000257497(transcript)|ensembl:ENST00000376911(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0001780"(neutrophil homeostasis)|go:"GO:0001891"(phagocytic cup)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0002685"(regulation of leukocyte migration)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006909"(phagocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009986"(cell surface)|go:"GO:0010165"(response to X-ray)|go:"GO:0014839"(myoblast migration involved in skeletal muscle regeneration)|go:"GO:0016323"(basolateral plasma membrane)|refseq:XP_011516911.1|dip:DIP-32875N|go:"GO:0046883"(regulation of hormone secretion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0070459"(prolactin secretion)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071621"(granulocyte chemotaxis)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097350"(neutrophil clearance)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900138"(negative regulation of phospholipase A2 activity)|go:"GO:1990814"(DNA/DNA annealing activity)|interpro:IPR001464(Annexin)|interpro:IPR002388(Annexin, type I)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P04083|rcsb pdb:1AIN|rcsb pdb:1BO9|rcsb pdb:1QLS|rcsb pdb:5VFW|reactome:R-HSA-416476|reactome:R-HSA-418594|reactome:R-HSA-444473|reactome:R-HSA-445355|reactome:R-HSA-6785807|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050482"(arachidonic acid secretion)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0050727"(regulation of inflammatory response) - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:vh/dDMpcLQEo57Wcjnggufh6HRk9606 rogid:QKmqz+UsAof35B/so2qKLQjn2v09606 rigid:0zUcpcUMAoZNa4lAzH7QV8gfQRo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UHJ3 uniprotkb:P80188 intact:EBI-747398|uniprotkb:Q96C73|uniprotkb:Q9Y4Q9|uniprotkb:Q402F7|ensembl:ENSP00000378235 intact:EBI-11911016|uniprotkb:A6NII8|uniprotkb:B4DWV4|uniprotkb:B7ZAA2|uniprotkb:P30150|uniprotkb:Q5SYV9|uniprotkb:Q5SYW0|uniprotkb:Q6FGL5|uniprotkb:Q92683|ensembl:ENSP00000277480|ensembl:ENSP00000362108 psi-mi:smbt1_human(display_long)|uniprotkb:Renal ubiquitous protein 1(gene name synonym)|uniprotkb:SFMBT1(gene name)|psi-mi:SFMBT1(display_short)|uniprotkb:RU1(gene name synonym) psi-mi:ngal_human(display_long)|uniprotkb:Siderocalin(gene name synonym)|uniprotkb:LCN2(gene name)|psi-mi:LCN2(display_short)|uniprotkb:25 kDa alpha-2-microglobulin-related subunit of MMP-9(gene name synonym)|uniprotkb:HNL(gene name synonym)|uniprotkb:Lipocalin-2(gene name synonym)|uniprotkb:NGAL(gene name synonym)|uniprotkb:Oncogene 24p3(gene name synonym)|uniprotkb:p25(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484663|imex:IM-26985-507 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006713266.1|refseq:XP_006713267.1|refseq:NP_057413.2|refseq:XP_011532126.1|refseq:XP_011532127.1|refseq:XP_005265278.1|ensembl:ENSG00000163935(gene)|ensembl:ENST00000394752(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048635"(negative regulation of muscle organ development)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR037604|interpro:IPR038348|mint:Q9UHJ3 refseq:NP_005555.2|dip:DIP-29952N|ensembl:ENSG00000148346(gene)|ensembl:ENST00000277480(transcript)|ensembl:ENST00000373017(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0005506"(iron ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0009635"(response to herbicide)|go:"GO:0009637"(response to blue light)|go:"GO:0010040"("response to iron(II) ion")|go:"GO:0010046"(response to mycotoxin)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0015891"(siderophore transport)|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0035580"(specific granule lumen)|go:"GO:0036094"(small molecule binding)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0042493"|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0045087"(innate immune response)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071354"(cellular response to interleukin-6)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:0097577"(sequestering of iron ion)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903981"(enterobactin binding)|go:"GO:1904440"(positive regulation of iron ion import across plasma membrane)|go:"GO:1904646"(cellular response to amyloid-beta)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR002345(Lipocalin)|interpro:IPR003087(Neutrophil gelatinase-associated lipocalin)|interpro:IPR012674(Calycin)|interpro:IPR022272|mint:P80188|rcsb pdb:1DFV|rcsb pdb:1L6M|rcsb pdb:1NGL|rcsb pdb:1QQS|rcsb pdb:1X71|rcsb pdb:1X89|rcsb pdb:1X8U|rcsb pdb:3BY0|rcsb pdb:3CBC|rcsb pdb:3CMP|rcsb pdb:3DSZ|rcsb pdb:3DTQ|rcsb pdb:3FW4|rcsb pdb:3FW5|rcsb pdb:3HWD|rcsb pdb:3HWE|rcsb pdb:3HWF|rcsb pdb:3HWG|rcsb pdb:3I0A|rcsb pdb:3K3L|rcsb pdb:3PEC|rcsb pdb:3PED|rcsb pdb:3T1D|rcsb pdb:3TF6|rcsb pdb:3TZS|rcsb pdb:3U0D|rcsb pdb:4GH7|rcsb pdb:4IAW|rcsb pdb:4IAX|rcsb pdb:4K19|rcsb pdb:4MVI|rcsb pdb:4MVK|rcsb pdb:4MVL|rcsb pdb:4QAE|rcsb pdb:4ZFX|rcsb pdb:4ZHC|rcsb pdb:4ZHD|rcsb pdb:4ZHF|rcsb pdb:4ZHG|rcsb pdb:4ZHH|rcsb pdb:5JR8|rcsb pdb:5KHP|go:"GO:1905956"(positive regulation of endothelial tube morphogenesis)|rcsb pdb:5KIC|rcsb pdb:5KID|rcsb pdb:5MHH|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:5NKN|rcsb pdb:6GQZ|rcsb pdb:6GR0|rcsb pdb:6QMU|rcsb pdb:6S8V|rcsb pdb:6SUA|rcsb pdb:6Z2C|rcsb pdb:6Z6Z|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-6799990|reactome:R-HSA-917937|rcsb pdb:6O5D - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:vh/dDMpcLQEo57Wcjnggufh6HRk9606 rogid:m5Q9A8rMP15tT8/Sdt2q/a3Xsr89606 rigid:0zUcpcUMAoZNa4lAzH7QV8gfQRo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UHJ3 uniprotkb:P47929 intact:EBI-747398|uniprotkb:Q96C73|uniprotkb:Q9Y4Q9|uniprotkb:Q402F7|ensembl:ENSP00000378235 intact:EBI-357504|ensembl:ENSP00000313571|ensembl:ENSP00000367891|ensembl:ENSP00000489395|ensembl:ENSP00000489582|uniprotkb:Q6IB87 psi-mi:smbt1_human(display_long)|uniprotkb:Renal ubiquitous protein 1(gene name synonym)|uniprotkb:SFMBT1(gene name)|psi-mi:SFMBT1(display_short)|uniprotkb:RU1(gene name synonym) psi-mi:leg7_human(display_long)|uniprotkb:LGALS7(gene name)|psi-mi:LGALS7(display_short)|uniprotkb:PIG1(gene name synonym)|uniprotkb:HKL-14(gene name synonym)|uniprotkb:PI7(gene name synonym)|uniprotkb:p53-induced gene 1 protein(gene name synonym)|uniprotkb:LGALS7B(gene name)|psi-mi:LGALS7B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484663|imex:IM-26985-507 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006713266.1|refseq:XP_006713267.1|refseq:NP_057413.2|refseq:XP_011532126.1|refseq:XP_011532127.1|refseq:XP_005265278.1|ensembl:ENSG00000163935(gene)|ensembl:ENST00000394752(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048635"(negative regulation of muscle organ development)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR037604|interpro:IPR038348|mint:Q9UHJ3 ensembl:ENSG00000178934(gene)|ensembl:ENSG00000205076(gene)|ensembl:ENSG00000282902(gene)|ensembl:ENSG00000283082(gene)|ensembl:ENST00000314980(transcript)|ensembl:ENST00000378626(transcript)|ensembl:ENST00000634448(transcript)|ensembl:ENST00000634800(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016936"(galactoside binding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0032689"(negative regulation of interferon-gamma production)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000562"(negative regulation of CD4-positive, alpha-beta T cell proliferation)|interpro:IPR001079(Galectin, galactose-binding lectin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR030640|interpro:IPR044156|mint:P47929|rcsb pdb:1BKZ|rcsb pdb:2GAL|rcsb pdb:3GAL|rcsb pdb:3ZXE|rcsb pdb:3ZXF|rcsb pdb:4GAL|rcsb pdb:4UW3|rcsb pdb:4UW4|rcsb pdb:4UW5|rcsb pdb:4UW6|rcsb pdb:4XBQ|rcsb pdb:4Y26|rcsb pdb:5GAL|rcsb pdb:5H9Q|rcsb pdb:5H9S|refseq:NP_001035972.1|refseq:NP_002298.1 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:vh/dDMpcLQEo57Wcjnggufh6HRk9606 rogid:TIAlvVZ7rOYqTAGrYAFbJY231gc9606 rigid:0zUcpcUMAoZNa4lAzH7QV8gfQRo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UHJ3 uniprotkb:P62979 intact:EBI-747398|uniprotkb:Q96C73|uniprotkb:Q9Y4Q9|uniprotkb:Q402F7|ensembl:ENSP00000378235 intact:EBI-357375|ensembl:ENSP00000272317|ensembl:ENSP00000383981|ensembl:ENSP00000385659|uniprotkb:P14798|uniprotkb:Q6LBL4|uniprotkb:Q9BQ77|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62988|uniprotkb:Q29120|uniprotkb:Q6LDU5|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9BWD6|uniprotkb:Q9BX98|uniprotkb:Q9UEF2|uniprotkb:Q9UEG1|uniprotkb:Q9UEK8|uniprotkb:Q9UPK7 psi-mi:smbt1_human(display_long)|uniprotkb:Renal ubiquitous protein 1(gene name synonym)|uniprotkb:SFMBT1(gene name)|psi-mi:SFMBT1(display_short)|uniprotkb:RU1(gene name synonym) psi-mi:rs27a_human(display_long)|uniprotkb:RPS27A(gene name)|psi-mi:RPS27A(display_short)|uniprotkb:UBA80(gene name synonym)|uniprotkb:UBCEP1(gene name synonym)|uniprotkb:Ubiquitin carboxyl extension protein 80(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484663|imex:IM-26985-507 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006713266.1|refseq:XP_006713267.1|refseq:NP_057413.2|refseq:XP_011532126.1|refseq:XP_011532127.1|refseq:XP_005265278.1|ensembl:ENSG00000163935(gene)|ensembl:ENST00000394752(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048635"(negative regulation of muscle organ development)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR037604|interpro:IPR038348|mint:Q9UHJ3 reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8863795|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-8854050|reactome:R-HSA-8951664|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9633012|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9683683|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-975110|reactome:R-HSA-975163|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-977225|reactome:R-HSA-983168|reactome:R-HSA-975144|ensembl:ENSG00000143947(gene)|ensembl:ENST00000272317(transcript)|ensembl:ENST00000402285(transcript)|ensembl:ENST00000404735(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0010008"(endosome membrane)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000626(Ubiquitin)|interpro:IPR002906(Ribosomal protein S27a)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038582|mint:P62979|rcsb pdb:2KHW|rcsb pdb:2KOX|rcsb pdb:2KTF|rcsb pdb:2KWU|rcsb pdb:2KWV|rcsb pdb:2L0F|rcsb pdb:2L0T|rcsb pdb:2XK5|rcsb pdb:3AXC|rcsb pdb:3I3T|rcsb pdb:3K9P|rcsb pdb:3N30|rcsb pdb:3N32|rcsb pdb:3NHE|rcsb pdb:3NOB|rcsb pdb:3NS8|rcsb pdb:3PHD|rcsb pdb:3PHW|rcsb pdb:3TBL|rcsb pdb:3VDZ|rcsb pdb:4R62|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:5A2Q|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:5AJ0|rcsb pdb:6IP8|rcsb pdb:6J99|rcsb pdb:5FLX|rcsb pdb:6KFP|rcsb pdb:5LKS|rcsb pdb:6KG6|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SQO|rcsb pdb:5T2C|rcsb pdb:5WVO|rcsb pdb:6SQR|rcsb pdb:6SQS|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:5YDK|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6DC6|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:7K5I|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|reactome:R-HSA-1253288|reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:6ZXF|reactome:R-HSA-162588|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-168928|rcsb pdb:6ZXG|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|rcsb pdb:6ZXH|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-1799339|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|rcsb pdb:7A09|rcsb pdb:7BWD|reactome:R-HSA-192823|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-2565942|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-349425|reactome:R-HSA-211733|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-2122947|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-2122948|reactome:R-HSA-4641258|reactome:R-HSA-2173788|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-2173791|reactome:R-HSA-5357905|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2408557|reactome:R-HSA-2467813|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-2559585|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5656169|reactome:R-HSA-5656121|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6791226|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69231|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-8852276|refseq:NP_001129064.1|refseq:NP_001170884.1|refseq:NP_002945.1 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:vh/dDMpcLQEo57Wcjnggufh6HRk9606 rogid:2LSJafy6vjKHYZcZVx8zZaOXRis9606 rigid:0zUcpcUMAoZNa4lAzH7QV8gfQRo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UHJ3 uniprotkb:P31151 intact:EBI-747398|uniprotkb:Q96C73|uniprotkb:Q9Y4Q9|uniprotkb:Q402F7|ensembl:ENSP00000378235 intact:EBI-357520|uniprotkb:Q6FGE3|uniprotkb:Q5SY67|uniprotkb:Q9H1E2|ensembl:ENSP00000357711|ensembl:ENSP00000357712 psi-mi:smbt1_human(display_long)|uniprotkb:Renal ubiquitous protein 1(gene name synonym)|uniprotkb:SFMBT1(gene name)|psi-mi:SFMBT1(display_short)|uniprotkb:RU1(gene name synonym) psi-mi:s10a7_human(display_long)|uniprotkb:S100A7(gene name)|psi-mi:S100A7(display_short)|uniprotkb:PSOR1(gene name synonym)|uniprotkb:S100A7C(gene name synonym)|uniprotkb:S100 calcium-binding protein A7(gene name synonym)|uniprotkb:Psoriasin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484663|imex:IM-26985-507 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006713266.1|refseq:XP_006713267.1|refseq:NP_057413.2|refseq:XP_011532126.1|refseq:XP_011532127.1|refseq:XP_005265278.1|ensembl:ENSG00000163935(gene)|ensembl:ENST00000394752(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048635"(negative regulation of muscle organ development)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR037604|interpro:IPR038348|mint:Q9UHJ3 ensembl:ENSG00000143556(gene)|ensembl:ENST00000368722(transcript)|ensembl:ENST00000368723(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001525"(angiogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008544"(epidermis development)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045087"(innate immune response)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051238"(sequestering of metal ion)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071624"(positive regulation of granulocyte chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028477|interpro:IPR034325|mint:P31151|rcsb pdb:1PSR|rcsb pdb:2PSR|rcsb pdb:2WND|rcsb pdb:2WOR|rcsb pdb:2WOS|rcsb pdb:3PSR|rcsb pdb:4AQJ|reactome:R-HSA-6798695|reactome:R-HSA-6799990|refseq:NP_002954.2 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:vh/dDMpcLQEo57Wcjnggufh6HRk9606 rogid:/v8+XQ7rCMTYzq9k/KqjcSm/G0A9606 rigid:0zUcpcUMAoZNa4lAzH7QV8gfQRo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UHJ3 uniprotkb:P27482 intact:EBI-747398|uniprotkb:Q96C73|uniprotkb:Q9Y4Q9|uniprotkb:Q402F7|ensembl:ENSP00000378235 intact:EBI-747537|uniprotkb:Q5SQI4|uniprotkb:B2R9V6|ensembl:ENSP00000315299 psi-mi:smbt1_human(display_long)|uniprotkb:Renal ubiquitous protein 1(gene name synonym)|uniprotkb:SFMBT1(gene name)|psi-mi:SFMBT1(display_short)|uniprotkb:RU1(gene name synonym) psi-mi:call3_human(display_long)|uniprotkb:Calmodulin-related protein NB-1(gene name synonym)|uniprotkb:CaM-like protein(gene name synonym)|uniprotkb:CALML3(gene name)|psi-mi:CALML3(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484663|imex:IM-26985-507 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006713266.1|refseq:XP_006713267.1|refseq:NP_057413.2|refseq:XP_011532126.1|refseq:XP_011532127.1|refseq:XP_005265278.1|ensembl:ENSG00000163935(gene)|ensembl:ENST00000394752(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048635"(negative regulation of muscle organ development)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR037604|interpro:IPR038348|mint:Q9UHJ3 refseq:NP_005176.1|ensembl:ENSG00000178363(gene)|ensembl:ENST00000315238(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P27482|rcsb pdb:1GGZ - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:vh/dDMpcLQEo57Wcjnggufh6HRk9606 rogid:7yRRBYvsbUxzIvnYaNmaIJ42i5Y9606 rigid:0zUcpcUMAoZNa4lAzH7QV8gfQRo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UHJ3 uniprotkb:P29508 intact:EBI-747398|uniprotkb:Q96C73|uniprotkb:Q9Y4Q9|uniprotkb:Q402F7|ensembl:ENSP00000378235 intact:EBI-359110|uniprotkb:Q53H28|uniprotkb:Q86VF3|uniprotkb:Q86W04|uniprotkb:Q8IWL4|uniprotkb:Q8IXI3|uniprotkb:Q9BYF8|uniprotkb:Q53YB5|uniprotkb:Q96J21|uniprotkb:B2RBT5|uniprotkb:A6NDM2|uniprotkb:B3W5Y6|ensembl:ENSP00000283752 psi-mi:smbt1_human(display_long)|uniprotkb:Renal ubiquitous protein 1(gene name synonym)|uniprotkb:SFMBT1(gene name)|psi-mi:SFMBT1(display_short)|uniprotkb:RU1(gene name synonym) psi-mi:spb3_human(display_long)|uniprotkb:SERPINB3(gene name)|psi-mi:SERPINB3(display_short)|uniprotkb:SCCA(gene name synonym)|uniprotkb:SCCA1(gene name synonym)|uniprotkb:Squamous cell carcinoma antigen 1(gene name synonym)|uniprotkb:Protein T4-A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484663|imex:IM-26985-507 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006713266.1|refseq:XP_006713267.1|refseq:NP_057413.2|refseq:XP_011532126.1|refseq:XP_011532127.1|refseq:XP_005265278.1|ensembl:ENSG00000163935(gene)|ensembl:ENST00000394752(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048635"(negative regulation of muscle organ development)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR037604|interpro:IPR038348|mint:Q9UHJ3 refseq:NP_008850.1|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031982"(vesicle)|go:"GO:0035425"(autocrine signaling)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0038001"(paracrine signaling)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043508"(negative regulation of JUN kinase activity)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P29508|rcsb pdb:2ZV6|rcsb pdb:4ZK0|rcsb pdb:4ZK3|reactome:R-HSA-6798695|ensembl:ENSG00000057149(gene)|ensembl:ENST00000283752(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002020"(protease binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity) - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:vh/dDMpcLQEo57Wcjnggufh6HRk9606 rogid:Q6rcSr7BU3XXRUX39SbdLT6Nm5s9606 rigid:0zUcpcUMAoZNa4lAzH7QV8gfQRo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UHJ3 uniprotkb:Q9UKL0 intact:EBI-747398|uniprotkb:Q96C73|uniprotkb:Q9Y4Q9|uniprotkb:Q402F7|ensembl:ENSP00000378235 intact:EBI-926563|uniprotkb:Q15044|uniprotkb:Q6P2I9|uniprotkb:Q86VG5|intact:EBI-11087913|uniprotkb:J3KN32|ensembl:ENSP00000262241 psi-mi:smbt1_human(display_long)|uniprotkb:Renal ubiquitous protein 1(gene name synonym)|uniprotkb:SFMBT1(gene name)|psi-mi:SFMBT1(display_short)|uniprotkb:RU1(gene name synonym) psi-mi:rcor1_human(display_long)|uniprotkb:RCOR1(gene name)|psi-mi:RCOR1(display_short)|uniprotkb:KIAA0071(gene name synonym)|uniprotkb:RCOR(gene name synonym)|uniprotkb:Protein CoREST(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484663|imex:IM-26985-507 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006713266.1|refseq:XP_006713267.1|refseq:NP_057413.2|refseq:XP_011532126.1|refseq:XP_011532127.1|refseq:XP_005265278.1|ensembl:ENSG00000163935(gene)|ensembl:ENST00000394752(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048635"(negative regulation of muscle organ development)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR037604|interpro:IPR038348|mint:Q9UHJ3 refseq:NP_055971.2|dip:DIP-35263N|ensembl:ENSG00000089902(gene)|ensembl:ENST00000262241(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0045654"(positive regulation of megakaryocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:1990391"(DNA repair complex)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|mint:Q9UKL0|rcsb pdb:2IW5|rcsb pdb:2UXN|rcsb pdb:2UXX|rcsb pdb:2V1D|rcsb pdb:2X0L|rcsb pdb:2XAF|rcsb pdb:2XAG|rcsb pdb:2XAH|rcsb pdb:2XAJ|rcsb pdb:2XAQ|rcsb pdb:2XAS|rcsb pdb:2Y48|rcsb pdb:3ZMS|rcsb pdb:3ZMT|rcsb pdb:3ZMU|rcsb pdb:3ZMV|rcsb pdb:3ZMZ|rcsb pdb:3ZN0|rcsb pdb:3ZN1|rcsb pdb:4BAY|rcsb pdb:4KUM|rcsb pdb:4UV8|rcsb pdb:4UV9|rcsb pdb:4UVA|rcsb pdb:4UVB|rcsb pdb:4UVC|rcsb pdb:4UXN|rcsb pdb:4XBF|rcsb pdb:5H6Q|rcsb pdb:5H6R|rcsb pdb:5L3B|rcsb pdb:5L3C|rcsb pdb:5L3D|rcsb pdb:5L3E|rcsb pdb:5L3F|rcsb pdb:5L3G|rcsb pdb:5LBQ|rcsb pdb:5LGN|rcsb pdb:5LGT|rcsb pdb:5LGU|rcsb pdb:5LHG|rcsb pdb:5LHH|rcsb pdb:5LHI|rcsb pdb:5X60|rcsb pdb:5YJB|rcsb pdb:6K3E|rcsb pdb:6KGK|rcsb pdb:6KGL|rcsb pdb:6KGM|rcsb pdb:6KGN|rcsb pdb:6S35|rcsb pdb:6TE1|rcsb pdb:6VYP|rcsb pdb:6W4K|rcsb pdb:6WC6|rcsb pdb:7CDC|rcsb pdb:7CDD|rcsb pdb:7CDE|rcsb pdb:7CDF|rcsb pdb:7CDG|reactome:R-HSA-3214815|reactome:R-HSA-8943724|reactome:R-HSA-9679191|reactome:R-HSA-983231 - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:vh/dDMpcLQEo57Wcjnggufh6HRk9606 rogid:B1KfnjicGzKdWGnGGrZwjgpMQ309606 rigid:0zUcpcUMAoZNa4lAzH7QV8gfQRo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UHJ3 uniprotkb:P06702 intact:EBI-747398|uniprotkb:Q96C73|uniprotkb:Q9Y4Q9|uniprotkb:Q402F7|ensembl:ENSP00000378235 intact:EBI-1055001|uniprotkb:Q6FGA1|uniprotkb:Q9NYM0|uniprotkb:Q9UCJ1|uniprotkb:D3DV36|ensembl:ENSP00000357727 psi-mi:smbt1_human(display_long)|uniprotkb:Renal ubiquitous protein 1(gene name synonym)|uniprotkb:SFMBT1(gene name)|psi-mi:SFMBT1(display_short)|uniprotkb:RU1(gene name synonym) psi-mi:s10a9_human(display_long)|uniprotkb:S100 calcium-binding protein A9(gene name synonym)|uniprotkb:Calgranulin-B(gene name synonym)|uniprotkb:Migration inhibitory factor-related protein 14(gene name synonym)|uniprotkb:Leukocyte L1 complex heavy chain(gene name synonym)|uniprotkb:Calprotectin L1H subunit(gene name synonym)|uniprotkb:S100A9(gene name)|psi-mi:S100A9(display_short)|uniprotkb:CAGB(gene name synonym)|uniprotkb:CFAG(gene name synonym)|uniprotkb:MRP14(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484663|imex:IM-26985-507 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006713266.1|refseq:XP_006713267.1|refseq:NP_057413.2|refseq:XP_011532126.1|refseq:XP_011532127.1|refseq:XP_005265278.1|ensembl:ENSG00000163935(gene)|ensembl:ENST00000394752(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048635"(negative regulation of muscle organ development)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR037604|interpro:IPR038348|mint:Q9UHJ3 refseq:NP_002956.1|rcsb pdb:1XK4|rcsb pdb:4GGF|rcsb pdb:4XJK|rcsb pdb:5I8N|rcsb pdb:5W1F|rcsb pdb:6DS2|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5668599|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-6799990|ensembl:ENSG00000163220(gene)|ensembl:ENST00000368738(transcript)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035662"(Toll-like receptor 4 binding)|go:"GO:0035821"(modulation of process of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0045113"(regulation of integrin biosynthetic process)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070488"(neutrophil aggregation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|mint:P06702|rcsb pdb:1IRJ|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016209"(antioxidant activity)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0030054"(cell junction)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032119"(sequestering of zinc ion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035425"(autocrine signaling)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|dip:DIP-1166N - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:vh/dDMpcLQEo57Wcjnggufh6HRk9606 rogid:IGnX4DSnv8xMr5pY4T7X7vYos5A9606 rigid:0zUcpcUMAoZNa4lAzH7QV8gfQRo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UHJ3 uniprotkb:P48594 intact:EBI-747398|uniprotkb:Q96C73|uniprotkb:Q9Y4Q9|uniprotkb:Q402F7|ensembl:ENSP00000378235 intact:EBI-1055490|uniprotkb:A8K847|ensembl:ENSP00000343445 psi-mi:smbt1_human(display_long)|uniprotkb:Renal ubiquitous protein 1(gene name synonym)|uniprotkb:SFMBT1(gene name)|psi-mi:SFMBT1(display_short)|uniprotkb:RU1(gene name synonym) psi-mi:spb4_human(display_long)|uniprotkb:Squamous cell carcinoma antigen 2(gene name synonym)|uniprotkb:Leupin(gene name synonym)|uniprotkb:SERPINB4(gene name)|psi-mi:SERPINB4(display_short)|uniprotkb:SCCA2(gene name synonym)|uniprotkb:PI11(gene name synonym)|uniprotkb:Peptidase inhibitor 11(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484663|imex:IM-26985-507 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006713266.1|refseq:XP_006713267.1|refseq:NP_057413.2|refseq:XP_011532126.1|refseq:XP_011532127.1|refseq:XP_005265278.1|ensembl:ENSG00000163935(gene)|ensembl:ENST00000394752(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048635"(negative regulation of muscle organ development)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR037604|interpro:IPR038348|mint:Q9UHJ3 refseq:NP_778206.1|refseq:NP_002965.1|refseq:XP_011524440.1|ensembl:ENSG00000206073(gene)|ensembl:ENST00000341074(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030162"(regulation of proteolysis)|go:"GO:0042270"(protection from natural killer cell mediated cytotoxicity)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042185|mint:P48594|interpro:IPR042178 - - comment:"author score: 30" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:vh/dDMpcLQEo57Wcjnggufh6HRk9606 rogid:1kO3L409kom3vIvMuAuBuGZhiH89606 rigid:0zUcpcUMAoZNa4lAzH7QV8gfQRo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UHJ3 uniprotkb:Q9P2K3 intact:EBI-747398|uniprotkb:Q96C73|uniprotkb:Q9Y4Q9|uniprotkb:Q402F7|ensembl:ENSP00000378235 intact:EBI-743428|uniprotkb:B3KYA2|uniprotkb:B4DYY7|uniprotkb:Q5VT47|uniprotkb:Q7L9I5|uniprotkb:Q8N5U3|uniprotkb:Q9NV83|ensembl:ENSP00000355972 psi-mi:smbt1_human(display_long)|uniprotkb:Renal ubiquitous protein 1(gene name synonym)|uniprotkb:SFMBT1(gene name)|psi-mi:SFMBT1(display_short)|uniprotkb:RU1(gene name synonym) psi-mi:rcor3_human(display_long)|uniprotkb:RCOR3(gene name)|psi-mi:RCOR3(display_short)|uniprotkb:KIAA1343(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484663|imex:IM-26985-507 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006713266.1|refseq:XP_006713267.1|refseq:NP_057413.2|refseq:XP_011532126.1|refseq:XP_011532127.1|refseq:XP_005265278.1|ensembl:ENSG00000163935(gene)|ensembl:ENST00000394752(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048635"(negative regulation of muscle organ development)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR037604|interpro:IPR038348|mint:Q9UHJ3 rcsb pdb:4CZZ|refseq:NP_001129695.1|refseq:NP_001129696.2|refseq:NP_001129697.1|refseq:NP_060724.1|ensembl:ENSG00000117625(gene)|ensembl:ENST00000367005(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016575"(histone deacetylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|mint:Q9P2K3 - - comment:"author score: 35" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:vh/dDMpcLQEo57Wcjnggufh6HRk9606 rogid:hzuKCK7o/85XbN65z8Ua+XNaSJc9606 rigid:0zUcpcUMAoZNa4lAzH7QV8gfQRo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UHJ3 uniprotkb:O60341 intact:EBI-747398|uniprotkb:Q96C73|uniprotkb:Q9Y4Q9|uniprotkb:Q402F7|ensembl:ENSP00000378235 intact:EBI-710124|uniprotkb:Q5TH94|uniprotkb:Q5TH95|uniprotkb:Q86VT7|uniprotkb:Q8IXK4|uniprotkb:Q8NDP6|uniprotkb:Q8TAZ3|uniprotkb:Q96AW4|ensembl:ENSP00000349049|uniprotkb:A8MWP9 psi-mi:smbt1_human(display_long)|uniprotkb:Renal ubiquitous protein 1(gene name synonym)|uniprotkb:SFMBT1(gene name)|psi-mi:SFMBT1(display_short)|uniprotkb:RU1(gene name synonym) psi-mi:kdm1a_human(display_long)|uniprotkb:Flavin-containing amine oxidase domain-containing protein 2(gene name synonym)|uniprotkb:BRAF35-HDAC complex protein BHC110(gene name synonym)|uniprotkb:KDM1A(gene name)|psi-mi:KDM1A(display_short)|uniprotkb:KIAA0601(gene name synonym)|uniprotkb:LSD1(gene name synonym)|uniprotkb:AOF2(gene name synonym)|uniprotkb:KDM1(gene name synonym)|uniprotkb:"[histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1A"(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484663|imex:IM-26985-507 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006713266.1|refseq:XP_006713267.1|refseq:NP_057413.2|refseq:XP_011532126.1|refseq:XP_011532127.1|refseq:XP_005265278.1|ensembl:ENSG00000163935(gene)|ensembl:ENST00000394752(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048635"(negative regulation of muscle organ development)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR037604|interpro:IPR038348|mint:Q9UHJ3 go:"GO:0021987"(cerebral cortex development)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032451"(demethylase activity)|refseq:NP_001009999.1|refseq:NP_055828.2|ensembl:ENSG00000004487(gene)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006482"(protein demethylation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|ensembl:ENST00000356634(transcript)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|dip:DIP-34641N|go:"GO:0032452"(histone demethylase activity)|go:"GO:0032453"(histone H3-methyl-lysine-4 demethylase activity)|go:"GO:0032454"(histone H3-methyl-lysine-9 demethylase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033169"(histone H3-K9 demethylation)|go:"GO:0033184"(positive regulation of histone ubiquitination)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034648"("obsolete histone demethylase activity (H3-dimethyl-K4 specific)")|go:"GO:0034720"(histone H3-K4 demethylation)|go:"GO:0035563"(positive regulation of chromatin binding)|go:"GO:0042551"(neuron maturation)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043426"(MRF binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046098"(guanine metabolic process)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0051573"(negative regulation of histone H3-K9 methylation)|go:"GO:0055001"(muscle cell development)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0060992"(response to fungicide)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061752"(telomeric repeat-containing RNA binding)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1903827"|go:"GO:1990391"(DNA repair complex)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2000648"(positive regulation of stem cell proliferation)|interpro:IPR002937(Amine oxidase)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017366(Histone lysine-specific demethylase)|interpro:IPR036188|interpro:IPR036388|mint:O60341|rcsb pdb:2COM|rcsb pdb:2DW4|rcsb pdb:2EJR|rcsb pdb:2H94|rcsb pdb:2HKO|rcsb pdb:2IW5|rcsb pdb:2L3D|rcsb pdb:2UXN|rcsb pdb:2UXX|rcsb pdb:2V1D|rcsb pdb:2X0L|rcsb pdb:2XAF|rcsb pdb:2XAG|rcsb pdb:2XAH|rcsb pdb:2XAJ|rcsb pdb:2XAQ|rcsb pdb:2XAS|rcsb pdb:2Y48|rcsb pdb:2Z3Y|rcsb pdb:2Z5U|rcsb pdb:3ABT|rcsb pdb:3ABU|rcsb pdb:3ZMS|rcsb pdb:3ZMT|rcsb pdb:3ZMU|rcsb pdb:3ZMV|rcsb pdb:3ZMZ|rcsb pdb:3ZN0|rcsb pdb:3ZN1|rcsb pdb:4BAY|rcsb pdb:4CZZ|rcsb pdb:4KUM|rcsb pdb:4UV8|rcsb pdb:4UV9|rcsb pdb:4UVA|rcsb pdb:4UVB|rcsb pdb:4UVC|rcsb pdb:4UXN|rcsb pdb:4XBF|rcsb pdb:5AFW|rcsb pdb:5H6Q|rcsb pdb:5H6R|rcsb pdb:5IT3|rcsb pdb:5L3B|rcsb pdb:5L3C|rcsb pdb:5L3D|rcsb pdb:5L3E|rcsb pdb:5L3F|rcsb pdb:5L3G|rcsb pdb:5LBQ|rcsb pdb:5LGN|rcsb pdb:5LGT|rcsb pdb:5LGU|rcsb pdb:5LHG|rcsb pdb:5LHH|rcsb pdb:5LHI|rcsb pdb:5X60|rcsb pdb:5YJB|rcsb pdb:6E1F|rcsb pdb:6K3E|rcsb pdb:6KGK|rcsb pdb:6KGL|rcsb pdb:6KGM|rcsb pdb:6KGN|rcsb pdb:6KGO|rcsb pdb:6KGP|rcsb pdb:6KGQ|rcsb pdb:6KGR|rcsb pdb:6NQM|rcsb pdb:6NQU|rcsb pdb:6NR5|rcsb pdb:6S35|rcsb pdb:6TE1|rcsb pdb:6VYP|rcsb pdb:6W4K|rcsb pdb:6WC6|rcsb pdb:7CDC|rcsb pdb:7CDD|rcsb pdb:7CDE|rcsb pdb:7CDF|rcsb pdb:7CDG|rcsb pdb:7E0G|rcsb pdb:7JJL|rcsb pdb:7JJM|rcsb pdb:7JK7|reactome:R-HSA-3214815|reactome:R-HSA-3214842|reactome:R-HSA-5625886|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9029569|reactome:R-HSA-9679191|reactome:R-HSA-983231 - - comment:"author score: 39" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:vh/dDMpcLQEo57Wcjnggufh6HRk9606 rogid:rS9F23Rg1Ha6XOQSisWQfhKVFfs9606 rigid:0zUcpcUMAoZNa4lAzH7QV8gfQRo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UHJ3 uniprotkb:Q6SPF0 intact:EBI-747398|uniprotkb:Q96C73|uniprotkb:Q9Y4Q9|uniprotkb:Q402F7|ensembl:ENSP00000378235 intact:EBI-8833536|uniprotkb:Q96IM4|uniprotkb:Q6PIS7|uniprotkb:Q6P0R3 psi-mi:smbt1_human(display_long)|uniprotkb:Renal ubiquitous protein 1(gene name synonym)|uniprotkb:SFMBT1(gene name)|psi-mi:SFMBT1(display_short)|uniprotkb:RU1(gene name synonym) psi-mi:samd1_human(display_long)|uniprotkb:SAMD1(gene name)|psi-mi:SAMD1(display_short)|uniprotkb:Atherin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484663|imex:IM-26985-507 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_006713266.1|refseq:XP_006713267.1|refseq:NP_057413.2|refseq:XP_011532126.1|refseq:XP_011532127.1|refseq:XP_005265278.1|ensembl:ENSG00000163935(gene)|ensembl:ENST00000394752(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048635"(negative regulation of muscle organ development)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR004092(Mbt repeat)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR021987|interpro:IPR037604|interpro:IPR038348|mint:Q9UHJ3 mint:Q6SPF0|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|refseq:NP_612361.1|go:"GO:0005737"(cytoplasm)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|rcsb pdb:6LUI|rcsb pdb:6LUJ|rcsb pdb:6LUK|go:"GO:0003682"(chromatin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus) - - comment:"author score: 56" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:vh/dDMpcLQEo57Wcjnggufh6HRk9606 rogid:Cav/ZfHiZJ1xCBI6jAYrzv+CmZ49606 rigid:0zUcpcUMAoZNa4lAzH7QV8gfQRo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53H47 uniprotkb:Q92624 intact:EBI-717125|uniprotkb:Q13579|uniprotkb:Q1G668|uniprotkb:Q96F41|uniprotkb:B4DY74|uniprotkb:E7EN68|ensembl:ENSP00000373354 intact:EBI-743771|uniprotkb:O95095|uniprotkb:Q8WVC9|uniprotkb:A8K862|ensembl:ENSP00000083182 psi-mi:setmr_human(display_long)|uniprotkb:SET domain and mariner transposase fusion protein(gene name synonym)|uniprotkb:SETMAR(gene name)|psi-mi:SETMAR(display_short) psi-mi:apbp2_human(display_long)|uniprotkb:Amyloid beta precursor protein-binding protein 2(gene name synonym)|uniprotkb:Protein interacting with APP tail 1(gene name synonym)|uniprotkb:APPBP2(gene name)|psi-mi:APPBP2(display_short)|uniprotkb:KIAA0228(gene name synonym)|uniprotkb:PAT1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484648|imex:IM-26985-355 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006506.3|refseq:NP_001230652.1|refseq:NP_001307606.1|refseq:NP_001307607.1|refseq:NP_001263254.1|ensembl:ENSG00000170364(gene)|ensembl:ENST00000358065(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000737"(DNA catabolic process, endonucleolytic)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010452"(histone H3-K36 methylation)|go:"GO:0015074"(DNA integration)|go:"GO:0031297"(replication fork processing)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:0097676"(histone H3-K36 dimethylation)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001251"(negative regulation of chromosome organization)|interpro:IPR001214(SET)|interpro:IPR001888(Transposase, type 1)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR036388|interpro:IPR036397|interpro:IPR041426|mint:Q53H47|rcsb pdb:3BO5|rcsb pdb:3F2K|rcsb pdb:3K9J|rcsb pdb:3K9K|go:"GO:0051568"(histone H3-K4 methylation) refseq:NP_001269405.1|refseq:NP_006371.2|ensembl:ENSG00000062725(gene)|ensembl:ENST00000083182(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0046907"(intracellular transport)|go:"GO:1990756"(ubiquitin ligase-substrate adaptor activity)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q92624|interpro:IPR042476 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CPDzaHp2gTWPpT90wYydeWbZHRo9606 rogid:v3OsJTC6qSupyl7flB7A/tYhIDU9606 rigid:T/Vxvh6UkSt5R4GhIVfeao7mx2s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53H47 uniprotkb:Q15369 intact:EBI-717125|uniprotkb:Q13579|uniprotkb:Q1G668|uniprotkb:Q96F41|uniprotkb:B4DY74|uniprotkb:E7EN68|ensembl:ENSP00000373354 intact:EBI-301231|uniprotkb:Q567Q6|ensembl:ENSP00000284811|ensembl:ENSP00000428074|ensembl:ENSP00000428171|ensembl:ENSP00000428334|ensembl:ENSP00000429596|ensembl:ENSP00000429906|ensembl:ENSP00000478121|uniprotkb:E5RGD9 psi-mi:setmr_human(display_long)|uniprotkb:SET domain and mariner transposase fusion protein(gene name synonym)|uniprotkb:SETMAR(gene name)|psi-mi:SETMAR(display_short) psi-mi:eloc_human(display_long)|uniprotkb:ELOC(gene name)|psi-mi:ELOC(display_short)|uniprotkb:Elongin 15 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit C(gene name synonym)|uniprotkb:SIII p15(gene name synonym)|uniprotkb:TCEB1(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484648|imex:IM-26985-355 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006506.3|refseq:NP_001230652.1|refseq:NP_001307606.1|refseq:NP_001307607.1|refseq:NP_001263254.1|ensembl:ENSG00000170364(gene)|ensembl:ENST00000358065(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000737"(DNA catabolic process, endonucleolytic)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010452"(histone H3-K36 methylation)|go:"GO:0015074"(DNA integration)|go:"GO:0031297"(replication fork processing)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:0097676"(histone H3-K36 dimethylation)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001251"(negative regulation of chromosome organization)|interpro:IPR001214(SET)|interpro:IPR001888(Transposase, type 1)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR036388|interpro:IPR036397|interpro:IPR041426|mint:Q53H47|rcsb pdb:3BO5|rcsb pdb:3F2K|rcsb pdb:3K9J|rcsb pdb:3K9K|go:"GO:0051568"(histone H3-K4 methylation) refseq:NP_005639.1|refseq:NP_001191786.1|refseq:NP_001191787.1|refseq:NP_001191788.1|refseq:NP_001191789.1|refseq:NP_001191790.1|refseq:NP_001191791.1|refseq:NP_001191792.1|refseq:NP_001191793.1|ensembl:ENSG00000154582(gene)|ensembl:ENST00000284811(transcript)|ensembl:ENST00000518127(transcript)|ensembl:ENST00000519487(transcript)|ensembl:ENST00000520242(transcript)|ensembl:ENST00000522337(transcript)|ensembl:ENST00000523815(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0070449"(elongin complex)|interpro:IPR001232(SKP1 component)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR016073(SKP1 component, POZ)|interpro:IPR039948|mint:Q15369|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|ensembl:ENST00000622804(transcript)|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:4WQO|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:6HAX|rcsb pdb:6GFY|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7N|rcsb pdb:6SIS|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|reactome:R-HSA-167200|refseq:XP_011515882.1|refseq:XP_011515883.1|dip:DIP-29571N - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CPDzaHp2gTWPpT90wYydeWbZHRo9606 rogid:Ngvkh3YoddZoutF3Vgwdi2b6xz49606 rigid:T/Vxvh6UkSt5R4GhIVfeao7mx2s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q53H47 uniprotkb:Q15370 intact:EBI-717125|uniprotkb:Q13579|uniprotkb:Q1G668|uniprotkb:Q96F41|uniprotkb:B4DY74|uniprotkb:E7EN68|ensembl:ENSP00000373354 intact:EBI-301238|ensembl:ENSP00000386652|uniprotkb:B7WPD3 psi-mi:setmr_human(display_long)|uniprotkb:SET domain and mariner transposase fusion protein(gene name synonym)|uniprotkb:SETMAR(gene name)|psi-mi:SETMAR(display_short) psi-mi:elob_human(display_long)|uniprotkb:ELOB(gene name)|psi-mi:ELOB(display_short)|uniprotkb:Elongin 18 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase II transcription factor SIII subunit B(gene name synonym)|uniprotkb:SIII p18(gene name synonym)|uniprotkb:TCEB2(gene name synonym)|uniprotkb:Transcription elongation factor B polypeptide 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484648|imex:IM-26985-355 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006506.3|refseq:NP_001230652.1|refseq:NP_001307606.1|refseq:NP_001307607.1|refseq:NP_001263254.1|ensembl:ENSG00000170364(gene)|ensembl:ENST00000358065(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000737"(DNA catabolic process, endonucleolytic)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010452"(histone H3-K36 methylation)|go:"GO:0015074"(DNA integration)|go:"GO:0031297"(replication fork processing)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0044774"(mitotic DNA integrity checkpoint signaling)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:0097676"(histone H3-K36 dimethylation)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|go:"GO:2001251"(negative regulation of chromosome organization)|interpro:IPR001214(SET)|interpro:IPR001888(Transposase, type 1)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR036388|interpro:IPR036397|interpro:IPR041426|mint:Q53H47|rcsb pdb:3BO5|rcsb pdb:3F2K|rcsb pdb:3K9J|rcsb pdb:3K9K|go:"GO:0051568"(histone H3-K4 methylation) ensembl:ENSG00000103363(gene)|ensembl:ENST00000409906(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030891"(VCB complex)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031466"(Cul5-RING ubiquitin ligase complex)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070449"(elongin complex)|interpro:IPR000626(Ubiquitin)|interpro:IPR029071|interpro:IPR039049|mint:Q15370|rcsb pdb:1LM8|rcsb pdb:1LQB|rcsb pdb:1VCB|rcsb pdb:2C9W|rcsb pdb:2IZV|rcsb pdb:2JZ3|rcsb pdb:2MA9|rcsb pdb:3DCG|rcsb pdb:3ZKJ|rcsb pdb:3ZNG|rcsb pdb:3ZRC|rcsb pdb:3ZRF|rcsb pdb:3ZTC|rcsb pdb:3ZTD|rcsb pdb:3ZUN|rcsb pdb:4AJY|rcsb pdb:4AWJ|rcsb pdb:4B95|rcsb pdb:4B9K|rcsb pdb:4BKS|rcsb pdb:4BKT|rcsb pdb:4N9F|rcsb pdb:4W9C|rcsb pdb:4W9D|rcsb pdb:4W9E|rcsb pdb:4W9F|rcsb pdb:4W9G|rcsb pdb:4W9H|rcsb pdb:4W9I|rcsb pdb:4W9J|rcsb pdb:4W9K|rcsb pdb:4W9L|rcsb pdb:5BO4|rcsb pdb:5LLI|rcsb pdb:5N4W|rcsb pdb:5NVV|rcsb pdb:5NVW|rcsb pdb:5NVX|rcsb pdb:5NVY|rcsb pdb:5NVZ|rcsb pdb:5NW0|rcsb pdb:5NW1|rcsb pdb:5NW2|rcsb pdb:5T35|rcsb pdb:6BVB|rcsb pdb:6C5X|rcsb pdb:6FMI|rcsb pdb:6FMJ|rcsb pdb:6FMK|rcsb pdb:6GFX|rcsb pdb:6GFY|rcsb pdb:6GFZ|rcsb pdb:6GMN|rcsb pdb:6GMQ|rcsb pdb:6GMR|rcsb pdb:6GMX|rcsb pdb:4WQO|rcsb pdb:6HAX|rcsb pdb:6HAY|rcsb pdb:6HR2|rcsb pdb:6I4X|rcsb pdb:6I5J|rcsb pdb:6I5N|rcsb pdb:6I7Q|rcsb pdb:6I7R|rcsb pdb:6P59|rcsb pdb:6R6H|rcsb pdb:6R7F|rcsb pdb:6R7H|rcsb pdb:6R7I|rcsb pdb:6R7N|rcsb pdb:6V9H|rcsb pdb:6ZHC|rcsb pdb:7KHH|reactome:R-HSA-112382|reactome:R-HSA-1234176|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-180585|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-75955|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9705462|reactome:R-HSA-983168|rcsb pdb:6SIS|refseq:NP_009039.1|refseq:NP_996896.1|dip:DIP-29570N - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CPDzaHp2gTWPpT90wYydeWbZHRo9606 rogid:apX4QFpDC4Dz3MAs7tQ8+XFHx6I9606 rigid:T/Vxvh6UkSt5R4GhIVfeao7mx2s false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQR1 uniprotkb:Q969R5 intact:EBI-1268946|uniprotkb:Q86W83|uniprotkb:Q8TD09|uniprotkb:A8K9D0 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 psi-mi:kmt5a_human(display_long)|uniprotkb:KMT5A(gene name)|psi-mi:KMT5A(display_short)|uniprotkb:H4-K20-HMTase KMT5A(gene name synonym)|uniprotkb:Histone-lysine N-methyltransferase KMT5A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 5A(gene name synonym)|uniprotkb:Lysine-specific methylase 5A(gene name synonym)|uniprotkb:PR/SET domain-containing protein 07(gene name synonym)|uniprotkb:PRSET7(gene name synonym)|uniprotkb:SET domain-containing protein 8(gene name synonym)|uniprotkb:SET07(gene name synonym)|uniprotkb:SET8(gene name synonym)|uniprotkb:SETD8(gene name synonym) psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484537|imex:IM-26985-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065115.3|dip:DIP-39133N|refseq:NP_001311433.1|refseq:NP_001311434.1|refseq:NP_001311435.1|mint:Q9NQR1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR016858(Histone H4-K20 methyltransferase)|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:4IJ8|rcsb pdb:5HQ2|rcsb pdb:5T5G|rcsb pdb:5TEG|rcsb pdb:5TH7|rcsb pdb:5V2N|rcsb pdb:5W1Y|rcsb pdb:6BOZ|rcsb pdb:7D1Z|rcsb pdb:7D20|reactome:R-HSA-2299718|reactome:R-HSA-3214841|reactome:R-HSA-6804760 refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/0hb5/U7CI+EUSMe0fB1JfXa5zo9606 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rigid:LNNwlKezZncfL7+m45iaGnD72c0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQR1 uniprotkb:P62750 intact:EBI-1268946|uniprotkb:Q86W83|uniprotkb:Q8TD09|uniprotkb:A8K9D0 intact:EBI-353254|uniprotkb:P29316|uniprotkb:Q92774|uniprotkb:P39024|uniprotkb:B2R5B2|ensembl:ENSP00000389103 psi-mi:kmt5a_human(display_long)|uniprotkb:KMT5A(gene name)|psi-mi:KMT5A(display_short)|uniprotkb:H4-K20-HMTase KMT5A(gene name synonym)|uniprotkb:Histone-lysine N-methyltransferase KMT5A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 5A(gene name synonym)|uniprotkb:Lysine-specific methylase 5A(gene name synonym)|uniprotkb:PR/SET domain-containing protein 07(gene name synonym)|uniprotkb:PRSET7(gene name synonym)|uniprotkb:SET domain-containing protein 8(gene name synonym)|uniprotkb:SET07(gene name synonym)|uniprotkb:SET8(gene name synonym)|uniprotkb:SETD8(gene name synonym) psi-mi:rl23a_human(display_long)|uniprotkb:RPL23A(gene name)|psi-mi:RPL23A(display_short)|uniprotkb:Large ribosomal subunit protein uL23(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484537|imex:IM-26985-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065115.3|dip:DIP-39133N|refseq:NP_001311433.1|refseq:NP_001311434.1|refseq:NP_001311435.1|mint:Q9NQR1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR016858(Histone H4-K20 methyltransferase)|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:4IJ8|rcsb pdb:5HQ2|rcsb pdb:5T5G|rcsb pdb:5TEG|rcsb pdb:5TH7|rcsb pdb:5V2N|rcsb pdb:5W1Y|rcsb pdb:6BOZ|rcsb pdb:7D1Z|rcsb pdb:7D20|reactome:R-HSA-2299718|reactome:R-HSA-3214841|reactome:R-HSA-6804760 reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|refseq:NP_000975.2|ensembl:ENSG00000198242(gene)|ensembl:ENST00000422514(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904841"(TORC2 complex binding)|interpro:IPR001014(Ribosomal protein L23, conserved site)|interpro:IPR005633(Ribosomal protein L23/L25, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR013025(Ribosomal protein L25/L23)|interpro:IPR019985|mint:P62750|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/0hb5/U7CI+EUSMe0fB1JfXa5zo9606 rogid:lA1ubRFO9/Tl54Z1dKUzoCKvpAo9606 rigid:LNNwlKezZncfL7+m45iaGnD72c0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQR1 uniprotkb:P61513 intact:EBI-1268946|uniprotkb:Q86W83|uniprotkb:Q8TD09|uniprotkb:A8K9D0 intact:EBI-356793|uniprotkb:P12751|intact:EBI-1051378|uniprotkb:Q6FGF5|ensembl:ENSP00000418082 psi-mi:kmt5a_human(display_long)|uniprotkb:KMT5A(gene name)|psi-mi:KMT5A(display_short)|uniprotkb:H4-K20-HMTase KMT5A(gene name synonym)|uniprotkb:Histone-lysine N-methyltransferase KMT5A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 5A(gene name synonym)|uniprotkb:Lysine-specific methylase 5A(gene name synonym)|uniprotkb:PR/SET domain-containing protein 07(gene name synonym)|uniprotkb:PRSET7(gene name synonym)|uniprotkb:SET domain-containing protein 8(gene name synonym)|uniprotkb:SET07(gene name synonym)|uniprotkb:SET8(gene name synonym)|uniprotkb:SETD8(gene name synonym) psi-mi:rl37a_human(display_long)|uniprotkb:RPL37A(gene name)|psi-mi:RPL37A(display_short)|uniprotkb:Large ribosomal subunit protein eL43(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484537|imex:IM-26985-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065115.3|dip:DIP-39133N|refseq:NP_001311433.1|refseq:NP_001311434.1|refseq:NP_001311435.1|mint:Q9NQR1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR016858(Histone H4-K20 methyltransferase)|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:4IJ8|rcsb pdb:5HQ2|rcsb pdb:5T5G|rcsb pdb:5TEG|rcsb pdb:5TH7|rcsb pdb:5V2N|rcsb pdb:5W1Y|rcsb pdb:6BOZ|rcsb pdb:7D1Z|rcsb pdb:7D20|reactome:R-HSA-2299718|reactome:R-HSA-3214841|reactome:R-HSA-6804760 refseq:NP_000989.1|ensembl:ENSG00000197756(gene)|ensembl:ENST00000491306(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002674(Ribosomal protein L37ae)|interpro:IPR011331(Ribosomal protein L37ae/L37e, core)|interpro:IPR011332(Ribosomal protein, zinc-binding)|mint:P61513|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/0hb5/U7CI+EUSMe0fB1JfXa5zo9606 rogid:0kwO2cVd99FGF2+5FyWo94C83049606 rigid:LNNwlKezZncfL7+m45iaGnD72c0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQR1 uniprotkb:P05388 intact:EBI-1268946|uniprotkb:Q86W83|uniprotkb:Q8TD09|uniprotkb:A8K9D0 intact:EBI-354101|uniprotkb:Q9BVK4|intact:EBI-8012155|intact:MINT-8395053|uniprotkb:Q3B7A4|ensembl:ENSP00000339027|ensembl:ENSP00000376299|ensembl:ENSP00000449328 psi-mi:kmt5a_human(display_long)|uniprotkb:KMT5A(gene name)|psi-mi:KMT5A(display_short)|uniprotkb:H4-K20-HMTase KMT5A(gene name synonym)|uniprotkb:Histone-lysine N-methyltransferase KMT5A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 5A(gene name synonym)|uniprotkb:Lysine-specific methylase 5A(gene name synonym)|uniprotkb:PR/SET domain-containing protein 07(gene name synonym)|uniprotkb:PRSET7(gene name synonym)|uniprotkb:SET domain-containing protein 8(gene name synonym)|uniprotkb:SET07(gene name synonym)|uniprotkb:SET8(gene name synonym)|uniprotkb:SETD8(gene name synonym) psi-mi:rla0_human(display_long)|uniprotkb:RPLP0(gene name)|psi-mi:RPLP0(display_short)|uniprotkb:60S ribosomal protein L10E(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL10(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484537|imex:IM-26985-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065115.3|dip:DIP-39133N|refseq:NP_001311433.1|refseq:NP_001311434.1|refseq:NP_001311435.1|mint:Q9NQR1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR016858(Histone H4-K20 methyltransferase)|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:4IJ8|rcsb pdb:5HQ2|rcsb pdb:5T5G|rcsb pdb:5TEG|rcsb pdb:5TH7|rcsb pdb:5V2N|rcsb pdb:5W1Y|rcsb pdb:6BOZ|rcsb pdb:7D1Z|rcsb pdb:7D20|reactome:R-HSA-2299718|reactome:R-HSA-3214841|reactome:R-HSA-6804760 refseq:NP_000993.1|refseq:NP_444505.1|ensembl:ENSG00000089157(gene)|ensembl:ENST00000228306(transcript)|ensembl:ENST00000392514(transcript)|ensembl:ENST00000551150(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0030425"(dendrite)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070180"(large ribosomal subunit rRNA binding)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0098794"(postsynapse)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001790(Ribosomal protein L10)|interpro:IPR030670|interpro:IPR040637|interpro:IPR043141|interpro:IPR043164|mint:P05388|rcsb pdb:4V6W|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:6OLG|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-8950505|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/0hb5/U7CI+EUSMe0fB1JfXa5zo9606 rogid:xv3QHqnXxvCd3BOIeHVkqEnSNNk9606 rigid:LNNwlKezZncfL7+m45iaGnD72c0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQR1 uniprotkb:P62805 intact:EBI-1268946|uniprotkb:Q86W83|uniprotkb:Q8TD09|uniprotkb:A8K9D0 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:kmt5a_human(display_long)|uniprotkb:KMT5A(gene name)|psi-mi:KMT5A(display_short)|uniprotkb:H4-K20-HMTase KMT5A(gene name synonym)|uniprotkb:Histone-lysine N-methyltransferase KMT5A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 5A(gene name synonym)|uniprotkb:Lysine-specific methylase 5A(gene name synonym)|uniprotkb:PR/SET domain-containing protein 07(gene name synonym)|uniprotkb:PRSET7(gene name synonym)|uniprotkb:SET domain-containing protein 8(gene name synonym)|uniprotkb:SET07(gene name synonym)|uniprotkb:SET8(gene name synonym)|uniprotkb:SETD8(gene name synonym) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484537|imex:IM-26985-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065115.3|dip:DIP-39133N|refseq:NP_001311433.1|refseq:NP_001311434.1|refseq:NP_001311435.1|mint:Q9NQR1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR016858(Histone H4-K20 methyltransferase)|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:4IJ8|rcsb pdb:5HQ2|rcsb pdb:5T5G|rcsb pdb:5TEG|rcsb pdb:5TH7|rcsb pdb:5V2N|rcsb pdb:5W1Y|rcsb pdb:6BOZ|rcsb pdb:7D1Z|rcsb pdb:7D20|reactome:R-HSA-2299718|reactome:R-HSA-3214841|reactome:R-HSA-6804760 ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/0hb5/U7CI+EUSMe0fB1JfXa5zo9606 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 rigid:LNNwlKezZncfL7+m45iaGnD72c0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQR1 uniprotkb:Q99848 intact:EBI-1268946|uniprotkb:Q86W83|uniprotkb:Q8TD09|uniprotkb:A8K9D0 intact:EBI-1048111|uniprotkb:Q96A66|ensembl:ENSP00000236051 psi-mi:kmt5a_human(display_long)|uniprotkb:KMT5A(gene name)|psi-mi:KMT5A(display_short)|uniprotkb:H4-K20-HMTase KMT5A(gene name synonym)|uniprotkb:Histone-lysine N-methyltransferase KMT5A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 5A(gene name synonym)|uniprotkb:Lysine-specific methylase 5A(gene name synonym)|uniprotkb:PR/SET domain-containing protein 07(gene name synonym)|uniprotkb:PRSET7(gene name synonym)|uniprotkb:SET domain-containing protein 8(gene name synonym)|uniprotkb:SET07(gene name synonym)|uniprotkb:SET8(gene name synonym)|uniprotkb:SETD8(gene name synonym) psi-mi:ebp2_human(display_long)|uniprotkb:EBNA1-binding protein 2(gene name synonym)|uniprotkb:Nucleolar protein p40(gene name synonym)|uniprotkb:EBNA1BP2(gene name)|psi-mi:EBNA1BP2(display_short)|uniprotkb:EBP2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484537|imex:IM-26985-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065115.3|dip:DIP-39133N|refseq:NP_001311433.1|refseq:NP_001311434.1|refseq:NP_001311435.1|mint:Q9NQR1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR016858(Histone H4-K20 methyltransferase)|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:4IJ8|rcsb pdb:5HQ2|rcsb pdb:5T5G|rcsb pdb:5TEG|rcsb pdb:5TH7|rcsb pdb:5V2N|rcsb pdb:5W1Y|rcsb pdb:6BOZ|rcsb pdb:7D1Z|rcsb pdb:7D20|reactome:R-HSA-2299718|reactome:R-HSA-3214841|reactome:R-HSA-6804760 refseq:NP_001153408.1|refseq:NP_006815.2|ensembl:ENSG00000117395(gene)|ensembl:ENST00000236051(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR008610(Eukaryotic rRNA processing)|mint:Q99848|reactome:R-HSA-6791226 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/0hb5/U7CI+EUSMe0fB1JfXa5zo9606 rogid:lUFbxBko/pJHiNq8uuefmK3Xqp89606 rigid:LNNwlKezZncfL7+m45iaGnD72c0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQR1 uniprotkb:P07305 intact:EBI-1268946|uniprotkb:Q86W83|uniprotkb:Q8TD09|uniprotkb:A8K9D0 intact:EBI-725224|uniprotkb:Q6FG88|uniprotkb:Q8N6R3|uniprotkb:B4DRD6|uniprotkb:B2R6I0|ensembl:ENSP00000344504 psi-mi:kmt5a_human(display_long)|uniprotkb:KMT5A(gene name)|psi-mi:KMT5A(display_short)|uniprotkb:H4-K20-HMTase KMT5A(gene name synonym)|uniprotkb:Histone-lysine N-methyltransferase KMT5A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 5A(gene name synonym)|uniprotkb:Lysine-specific methylase 5A(gene name synonym)|uniprotkb:PR/SET domain-containing protein 07(gene name synonym)|uniprotkb:PRSET7(gene name synonym)|uniprotkb:SET domain-containing protein 8(gene name synonym)|uniprotkb:SET07(gene name synonym)|uniprotkb:SET8(gene name synonym)|uniprotkb:SETD8(gene name synonym) psi-mi:h10_human(display_long)|uniprotkb:H1-0(gene name)|psi-mi:H1-0(display_short)|uniprotkb:H1F0(gene name synonym)|uniprotkb:H1FV(gene name synonym)|uniprotkb:Histone H1'(gene name synonym)|uniprotkb:"Histone H1(0)"(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484537|imex:IM-26985-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065115.3|dip:DIP-39133N|refseq:NP_001311433.1|refseq:NP_001311434.1|refseq:NP_001311435.1|mint:Q9NQR1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR016858(Histone H4-K20 methyltransferase)|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:4IJ8|rcsb pdb:5HQ2|rcsb pdb:5T5G|rcsb pdb:5TEG|rcsb pdb:5TH7|rcsb pdb:5V2N|rcsb pdb:5W1Y|rcsb pdb:6BOZ|rcsb pdb:7D1Z|rcsb pdb:7D20|reactome:R-HSA-2299718|reactome:R-HSA-3214841|reactome:R-HSA-6804760 refseq:NP_005309.1|ensembl:ENSG00000189060(gene)|ensembl:ENST00000340857(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016458"(obsolete gene silencing)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016604"(nuclear body)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045910"(negative regulation of DNA recombination)|go:"GO:0005634"(nucleus)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P07305|rcsb pdb:6HQ1|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6N88|rcsb pdb:6N89|rcsb pdb:7DBP|rcsb pdb:7K5X|reactome:R-HSA-140342|reactome:R-HSA-2559584|dip:DIP-41775N - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/0hb5/U7CI+EUSMe0fB1JfXa5zo9606 rogid:7ir9Jz/gNZypmWkTopCusDQFEhs9606 rigid:LNNwlKezZncfL7+m45iaGnD72c0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQR1 uniprotkb:O76021 intact:EBI-1268946|uniprotkb:Q86W83|uniprotkb:Q8TD09|uniprotkb:A8K9D0 intact:EBI-358028|uniprotkb:Q2M1T7|uniprotkb:Q6PL22|uniprotkb:Q8IWS7|uniprotkb:Q8WUZ1|uniprotkb:Q9HDA9|uniprotkb:Q9Y3Z9|uniprotkb:B4DJ58|uniprotkb:D3DUG7|ensembl:ENSP00000460871 psi-mi:kmt5a_human(display_long)|uniprotkb:KMT5A(gene name)|psi-mi:KMT5A(display_short)|uniprotkb:H4-K20-HMTase KMT5A(gene name synonym)|uniprotkb:Histone-lysine N-methyltransferase KMT5A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 5A(gene name synonym)|uniprotkb:Lysine-specific methylase 5A(gene name synonym)|uniprotkb:PR/SET domain-containing protein 07(gene name synonym)|uniprotkb:PRSET7(gene name synonym)|uniprotkb:SET domain-containing protein 8(gene name synonym)|uniprotkb:SET07(gene name synonym)|uniprotkb:SET8(gene name synonym)|uniprotkb:SETD8(gene name synonym) psi-mi:rl1d1_human(display_long)|uniprotkb:RSL1D1(gene name)|psi-mi:RSL1D1(display_short)|uniprotkb:CSIG(gene name synonym)|uniprotkb:PBK1(gene name synonym)|uniprotkb:CATX11(gene name synonym)|uniprotkb:L12(orf name)|uniprotkb:Cellular senescence-inhibited gene protein(gene name synonym)|uniprotkb:Protein PBK1(gene name synonym)|uniprotkb:CATX-11(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484537|imex:IM-26985-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065115.3|dip:DIP-39133N|refseq:NP_001311433.1|refseq:NP_001311434.1|refseq:NP_001311435.1|mint:Q9NQR1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR016858(Histone H4-K20 methyltransferase)|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:4IJ8|rcsb pdb:5HQ2|rcsb pdb:5T5G|rcsb pdb:5TEG|rcsb pdb:5TH7|rcsb pdb:5V2N|rcsb pdb:5W1Y|rcsb pdb:6BOZ|rcsb pdb:7D1Z|rcsb pdb:7D20|reactome:R-HSA-2299718|reactome:R-HSA-3214841|reactome:R-HSA-6804760 refseq:NP_056474.2|ensembl:ENSG00000171490(gene)|ensembl:ENST00000571133(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0030686"(90S preribosome)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:2000772"(regulation of cellular senescence)|interpro:IPR016095(Ribosomal protein L1, 3-layer alpha/beta-sandwich)|interpro:IPR023674|interpro:IPR028364|mint:O76021 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/0hb5/U7CI+EUSMe0fB1JfXa5zo9606 rogid:/mAkpodrvvZA6mz3M8VwHDEJzKo9606 rigid:LNNwlKezZncfL7+m45iaGnD72c0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQR1 uniprotkb:P62899 intact:EBI-1268946|uniprotkb:Q86W83|uniprotkb:Q8TD09|uniprotkb:A8K9D0 intact:EBI-1053664|intact:EBI-3867511|uniprotkb:B7Z4K2|uniprotkb:P12947|uniprotkb:Q53SQ5|uniprotkb:Q6LBJ6|uniprotkb:D3DVJ4|uniprotkb:Q6IRZ0|ensembl:ENSP00000264258|ensembl:ENSP00000386681 psi-mi:kmt5a_human(display_long)|uniprotkb:KMT5A(gene name)|psi-mi:KMT5A(display_short)|uniprotkb:H4-K20-HMTase KMT5A(gene name synonym)|uniprotkb:Histone-lysine N-methyltransferase KMT5A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 5A(gene name synonym)|uniprotkb:Lysine-specific methylase 5A(gene name synonym)|uniprotkb:PR/SET domain-containing protein 07(gene name synonym)|uniprotkb:PRSET7(gene name synonym)|uniprotkb:SET domain-containing protein 8(gene name synonym)|uniprotkb:SET07(gene name synonym)|uniprotkb:SET8(gene name synonym)|uniprotkb:SETD8(gene name synonym) psi-mi:rl31_human(display_long)|uniprotkb:RPL31(gene name)|psi-mi:RPL31(display_short)|uniprotkb:Large ribosomal subunit protein eL31(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484537|imex:IM-26985-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065115.3|dip:DIP-39133N|refseq:NP_001311433.1|refseq:NP_001311434.1|refseq:NP_001311435.1|mint:Q9NQR1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR016858(Histone H4-K20 methyltransferase)|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:4IJ8|rcsb pdb:5HQ2|rcsb pdb:5T5G|rcsb pdb:5TEG|rcsb pdb:5TH7|rcsb pdb:5V2N|rcsb pdb:5W1Y|rcsb pdb:6BOZ|rcsb pdb:7D1Z|rcsb pdb:7D20|reactome:R-HSA-2299718|reactome:R-HSA-3214841|reactome:R-HSA-6804760 refseq:NP_000984.1|refseq:NP_001092047.1|refseq:NP_001093163.1|ensembl:ENSG00000071082(gene)|ensembl:ENST00000264258(transcript)|ensembl:ENST00000409733(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000054(Ribosomal protein L31e)|interpro:IPR020052|interpro:IPR023621|mint:P62899|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/0hb5/U7CI+EUSMe0fB1JfXa5zo9606 rogid:77LFR7/2somk6blVogZf1XFdJLk9606 rigid:LNNwlKezZncfL7+m45iaGnD72c0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQR1 uniprotkb:P18077 intact:EBI-1268946|uniprotkb:Q86W83|uniprotkb:Q8TD09|uniprotkb:A8K9D0 intact:EBI-353383|uniprotkb:Q08ES9|uniprotkb:Q9BVN7|ensembl:ENSP00000393393|ensembl:ENSP00000495672 psi-mi:kmt5a_human(display_long)|uniprotkb:KMT5A(gene name)|psi-mi:KMT5A(display_short)|uniprotkb:H4-K20-HMTase KMT5A(gene name synonym)|uniprotkb:Histone-lysine N-methyltransferase KMT5A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 5A(gene name synonym)|uniprotkb:Lysine-specific methylase 5A(gene name synonym)|uniprotkb:PR/SET domain-containing protein 07(gene name synonym)|uniprotkb:PRSET7(gene name synonym)|uniprotkb:SET domain-containing protein 8(gene name synonym)|uniprotkb:SET07(gene name synonym)|uniprotkb:SET8(gene name synonym)|uniprotkb:SETD8(gene name synonym) psi-mi:rl35a_human(display_long)|uniprotkb:RPL35A(gene name)|psi-mi:RPL35A(display_short)|uniprotkb:Cell growth-inhibiting gene 33 protein(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL33(gene name synonym)|uniprotkb:GIG33(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484537|imex:IM-26985-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065115.3|dip:DIP-39133N|refseq:NP_001311433.1|refseq:NP_001311434.1|refseq:NP_001311435.1|mint:Q9NQR1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR016858(Histone H4-K20 methyltransferase)|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:4IJ8|rcsb pdb:5HQ2|rcsb pdb:5T5G|rcsb pdb:5TEG|rcsb pdb:5TH7|rcsb pdb:5V2N|rcsb pdb:5W1Y|rcsb pdb:6BOZ|rcsb pdb:7D1Z|rcsb pdb:7D20|reactome:R-HSA-2299718|reactome:R-HSA-3214841|reactome:R-HSA-6804760 refseq:NP_000987.2|refseq:NP_001303240.1|ensembl:ENST00000647248(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001780(Ribosomal protein L35Ae)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR018266|interpro:IPR038661|mint:P18077|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|ensembl:ENSG00000182899(gene)|ensembl:ENST00000448864(transcript)|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/0hb5/U7CI+EUSMe0fB1JfXa5zo9606 rogid:fnUlL17LsiOp3lSkKNsoYO74IQQ9606 rigid:LNNwlKezZncfL7+m45iaGnD72c0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQR1 uniprotkb:Q92522 intact:EBI-1268946|uniprotkb:Q86W83|uniprotkb:Q8TD09|uniprotkb:A8K9D0 intact:EBI-876335|ensembl:ENSP00000329662 psi-mi:kmt5a_human(display_long)|uniprotkb:KMT5A(gene name)|psi-mi:KMT5A(display_short)|uniprotkb:H4-K20-HMTase KMT5A(gene name synonym)|uniprotkb:Histone-lysine N-methyltransferase KMT5A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 5A(gene name synonym)|uniprotkb:Lysine-specific methylase 5A(gene name synonym)|uniprotkb:PR/SET domain-containing protein 07(gene name synonym)|uniprotkb:PRSET7(gene name synonym)|uniprotkb:SET domain-containing protein 8(gene name synonym)|uniprotkb:SET07(gene name synonym)|uniprotkb:SET8(gene name synonym)|uniprotkb:SETD8(gene name synonym) psi-mi:h1x_human(display_long)|uniprotkb:H1-10(gene name)|psi-mi:H1-10(display_short)|uniprotkb:H1FX(gene name synonym)|uniprotkb:Histone H1x(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484537|imex:IM-26985-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065115.3|dip:DIP-39133N|refseq:NP_001311433.1|refseq:NP_001311434.1|refseq:NP_001311435.1|mint:Q9NQR1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR016858(Histone H4-K20 methyltransferase)|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:4IJ8|rcsb pdb:5HQ2|rcsb pdb:5T5G|rcsb pdb:5TEG|rcsb pdb:5TH7|rcsb pdb:5V2N|rcsb pdb:5W1Y|rcsb pdb:6BOZ|rcsb pdb:7D1Z|rcsb pdb:7D20|reactome:R-HSA-2299718|reactome:R-HSA-3214841|reactome:R-HSA-6804760 ensembl:ENSG00000184897(gene)|ensembl:ENST00000333762(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045296"(cadherin binding)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:Q92522|refseq:NP_006017.1|dip:DIP-36358N|rcsb pdb:2LSO|rcsb pdb:6L9Z|rcsb pdb:7K60|rcsb pdb:7K63 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/0hb5/U7CI+EUSMe0fB1JfXa5zo9606 rogid:T+NweCoHXj0rYsS6gJ4V42R9MpA9606 rigid:LNNwlKezZncfL7+m45iaGnD72c0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQR1 uniprotkb:Q02878 intact:EBI-1268946|uniprotkb:Q86W83|uniprotkb:Q8TD09|uniprotkb:A8K9D0 intact:EBI-359655|uniprotkb:Q2M3Q3|uniprotkb:Q8WW97|ensembl:ENSP00000202773|ensembl:ENSP00000403172 psi-mi:kmt5a_human(display_long)|uniprotkb:KMT5A(gene name)|psi-mi:KMT5A(display_short)|uniprotkb:H4-K20-HMTase KMT5A(gene name synonym)|uniprotkb:Histone-lysine N-methyltransferase KMT5A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 5A(gene name synonym)|uniprotkb:Lysine-specific methylase 5A(gene name synonym)|uniprotkb:PR/SET domain-containing protein 07(gene name synonym)|uniprotkb:PRSET7(gene name synonym)|uniprotkb:SET domain-containing protein 8(gene name synonym)|uniprotkb:SET07(gene name synonym)|uniprotkb:SET8(gene name synonym)|uniprotkb:SETD8(gene name synonym) psi-mi:rl6_human(display_long)|uniprotkb:RPL6(gene name)|psi-mi:RPL6(display_short)|uniprotkb:TXREB1(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 107(gene name synonym)|uniprotkb:Neoplasm-related protein C140(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484537|imex:IM-26985-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065115.3|dip:DIP-39133N|refseq:NP_001311433.1|refseq:NP_001311434.1|refseq:NP_001311435.1|mint:Q9NQR1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR016858(Histone H4-K20 methyltransferase)|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:4IJ8|rcsb pdb:5HQ2|rcsb pdb:5T5G|rcsb pdb:5TEG|rcsb pdb:5TH7|rcsb pdb:5V2N|rcsb pdb:5W1Y|rcsb pdb:6BOZ|rcsb pdb:7D1Z|rcsb pdb:7D20|reactome:R-HSA-2299718|reactome:R-HSA-3214841|reactome:R-HSA-6804760 refseq:NP_000961.2|refseq:NP_001019833.1|ensembl:ENSG00000089009(gene)|ensembl:ENST00000202773(transcript)|ensembl:ENST00000424576(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR000915(Ribosomal protein L6E)|interpro:IPR005568(Ribosomal protein L6, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041997|mint:Q02878|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001307066.1|refseq:NP_001307067.1|refseq:NP_001307068.1|refseq:NP_001307069.1|refseq:NP_001307070.1|refseq:XP_016875270.1|refseq:XP_016875271.1|dip:DIP-27547N - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/0hb5/U7CI+EUSMe0fB1JfXa5zo9606 rogid:Y7fx3ToInzucV2QmI8KLSdHxai09606 rigid:LNNwlKezZncfL7+m45iaGnD72c0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQR1 uniprotkb:Q13242 intact:EBI-1268946|uniprotkb:Q86W83|uniprotkb:Q8TD09|uniprotkb:A8K9D0 intact:EBI-2949710|ensembl:ENSP00000229390|uniprotkb:Q52LD1 psi-mi:kmt5a_human(display_long)|uniprotkb:KMT5A(gene name)|psi-mi:KMT5A(display_short)|uniprotkb:H4-K20-HMTase KMT5A(gene name synonym)|uniprotkb:Histone-lysine N-methyltransferase KMT5A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 5A(gene name synonym)|uniprotkb:Lysine-specific methylase 5A(gene name synonym)|uniprotkb:PR/SET domain-containing protein 07(gene name synonym)|uniprotkb:PRSET7(gene name synonym)|uniprotkb:SET domain-containing protein 8(gene name synonym)|uniprotkb:SET07(gene name synonym)|uniprotkb:SET8(gene name synonym)|uniprotkb:SETD8(gene name synonym) psi-mi:srsf9_human(display_long)|uniprotkb:SRSF9(gene name)|psi-mi:SRSF9(display_short)|uniprotkb:SFRS9(gene name synonym)|uniprotkb:SRP30C(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SRp30C(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484537|imex:IM-26985-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065115.3|dip:DIP-39133N|refseq:NP_001311433.1|refseq:NP_001311434.1|refseq:NP_001311435.1|mint:Q9NQR1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR016858(Histone H4-K20 methyltransferase)|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:4IJ8|rcsb pdb:5HQ2|rcsb pdb:5T5G|rcsb pdb:5TEG|rcsb pdb:5TH7|rcsb pdb:5V2N|rcsb pdb:5W1Y|rcsb pdb:6BOZ|rcsb pdb:7D1Z|rcsb pdb:7D20|reactome:R-HSA-2299718|reactome:R-HSA-3214841|reactome:R-HSA-6804760 go:"GO:0006397"(mRNA processing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043279"(response to alkaloid)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|go:"GO:0006376"(mRNA splice site selection)|interpro:IPR034503|interpro:IPR034995|interpro:IPR035979|mint:Q13242|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|ensembl:ENSG00000111786(gene)|ensembl:ENST00000229390(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|refseq:NP_003760.1|dip:DIP-40741N - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/0hb5/U7CI+EUSMe0fB1JfXa5zo9606 rogid:9x6TWFk1zN1YodjXBiwi/MtNJe49606 rigid:LNNwlKezZncfL7+m45iaGnD72c0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQR1 uniprotkb:P18124 intact:EBI-1268946|uniprotkb:Q86W83|uniprotkb:Q8TD09|uniprotkb:A8K9D0 intact:EBI-350806|uniprotkb:Q3KQU0|uniprotkb:Q15289|uniprotkb:Q5I0X1|uniprotkb:Q6IBM9|uniprotkb:A8K504|ensembl:ENSP00000339795 psi-mi:kmt5a_human(display_long)|uniprotkb:KMT5A(gene name)|psi-mi:KMT5A(display_short)|uniprotkb:H4-K20-HMTase KMT5A(gene name synonym)|uniprotkb:Histone-lysine N-methyltransferase KMT5A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 5A(gene name synonym)|uniprotkb:Lysine-specific methylase 5A(gene name synonym)|uniprotkb:PR/SET domain-containing protein 07(gene name synonym)|uniprotkb:PRSET7(gene name synonym)|uniprotkb:SET domain-containing protein 8(gene name synonym)|uniprotkb:SET07(gene name synonym)|uniprotkb:SET8(gene name synonym)|uniprotkb:SETD8(gene name synonym) psi-mi:rl7_human(display_long)|uniprotkb:RPL7(gene name)|psi-mi:RPL7(display_short)|uniprotkb:Large ribosomal subunit protein uL30(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484537|imex:IM-26985-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065115.3|dip:DIP-39133N|refseq:NP_001311433.1|refseq:NP_001311434.1|refseq:NP_001311435.1|mint:Q9NQR1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR016858(Histone H4-K20 methyltransferase)|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:4IJ8|rcsb pdb:5HQ2|rcsb pdb:5T5G|rcsb pdb:5TEG|rcsb pdb:5TH7|rcsb pdb:5V2N|rcsb pdb:5W1Y|rcsb pdb:6BOZ|rcsb pdb:7D1Z|rcsb pdb:7D20|reactome:R-HSA-2299718|reactome:R-HSA-3214841|reactome:R-HSA-6804760 refseq:NP_000962.2|ensembl:ENSG00000147604(gene)|ensembl:ENST00000352983(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR005998(Ribosomal protein L7, eukaryotic)|interpro:IPR012988(Ribosomal protein L30, N-terminal)|interpro:IPR016082(Ribosomal protein L30, C-terminal)|interpro:IPR018038|interpro:IPR035808|interpro:IPR036919|interpro:IPR039699|mint:P18124|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-72689 - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/0hb5/U7CI+EUSMe0fB1JfXa5zo9606 rogid:miVEaLOilDYcZXshxJlYbpnzwZ89606 rigid:LNNwlKezZncfL7+m45iaGnD72c0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQR1 uniprotkb:P07910 intact:EBI-1268946|uniprotkb:Q86W83|uniprotkb:Q8TD09|uniprotkb:A8K9D0 intact:EBI-357966|uniprotkb:P22628|uniprotkb:Q53EX2|uniprotkb:Q59FD3|uniprotkb:Q5FWE8|uniprotkb:Q86SF8|uniprotkb:Q86U45|uniprotkb:Q96HK7|uniprotkb:Q96HM4|uniprotkb:Q96IY5|uniprotkb:Q9BTS3|uniprotkb:D3DS19|uniprotkb:D3DS22|intact:EBI-28976506|ensembl:ENSP00000404848|ensembl:ENSP00000451291|ensembl:ENSP00000452276 psi-mi:kmt5a_human(display_long)|uniprotkb:KMT5A(gene name)|psi-mi:KMT5A(display_short)|uniprotkb:H4-K20-HMTase KMT5A(gene name synonym)|uniprotkb:Histone-lysine N-methyltransferase KMT5A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 5A(gene name synonym)|uniprotkb:Lysine-specific methylase 5A(gene name synonym)|uniprotkb:PR/SET domain-containing protein 07(gene name synonym)|uniprotkb:PRSET7(gene name synonym)|uniprotkb:SET domain-containing protein 8(gene name synonym)|uniprotkb:SET07(gene name synonym)|uniprotkb:SET8(gene name synonym)|uniprotkb:SETD8(gene name synonym) psi-mi:hnrpc_human(display_long)|uniprotkb:HNRNPC(gene name)|psi-mi:HNRNPC(display_short)|uniprotkb:HNRPC(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484537|imex:IM-26985-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065115.3|dip:DIP-39133N|refseq:NP_001311433.1|refseq:NP_001311434.1|refseq:NP_001311435.1|mint:Q9NQR1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR016858(Histone H4-K20 methyltransferase)|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:4IJ8|rcsb pdb:5HQ2|rcsb pdb:5T5G|rcsb pdb:5TEG|rcsb pdb:5TH7|rcsb pdb:5V2N|rcsb pdb:5W1Y|rcsb pdb:6BOZ|rcsb pdb:7D1Z|rcsb pdb:7D20|reactome:R-HSA-2299718|reactome:R-HSA-3214841|reactome:R-HSA-6804760 refseq:NP_001070910.1|refseq:NP_001070911.1|refseq:NP_004491.2|refseq:NP_112604.2|ensembl:ENSP00000404848|ensembl:ENST00000430246|ensembl:ENSP00000442816|ensembl:ENST00000553300|ensembl:ENSP00000450544|ensembl:ENSP00000451291|ensembl:ENST00000554969|ensembl:ENSP00000452276|ensembl:ENSP00000450725|ensembl:ENST00000555883|ensembl:ENSP00000450629|ensembl:ENST00000556628|ensembl:ENSP00000451652|ensembl:ENST00000556897|ensembl:ENSP00000451176|refseq:XP_011535010.1|refseq:XP_011535011.1|refseq:XP_011535012.1|refseq:XP_011535013.1|refseq:XP_011535014.1|refseq:XP_016876741.1|refseq:XP_016876742.1|dip:DIP-29854N|refseq:XP_006720188.1|ensembl:ENSG00000092199(gene)|ensembl:ENST00000420743(transcript)|ensembl:ENST00000554455(transcript)|ensembl:ENST00000557201(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008380"(RNA splicing)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017347(Heterogeneous nuclear ribonucleoprotein C, Raly)|interpro:IPR035979|mint:P07910|rcsb pdb:1TXP|rcsb pdb:1WF2|rcsb pdb:2MXY|rcsb pdb:2MZ1|rcsb pdb:3LN4|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422 - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/0hb5/U7CI+EUSMe0fB1JfXa5zo9606 rogid:Fj5tiH0wrNUjTnsURIg8dB8laMg9606 rigid:LNNwlKezZncfL7+m45iaGnD72c0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQR1 uniprotkb:P22626 intact:EBI-1268946|uniprotkb:Q86W83|uniprotkb:Q8TD09|uniprotkb:A8K9D0 intact:EBI-299649|ensembl:ENSP00000346694|ensembl:ENSP00000349101|ensembl:ENSP00000354021|ensembl:ENSP00000503360|ensembl:ENSP00000503476|ensembl:ENSP00000503514|ensembl:ENSP00000503885|ensembl:ENSP00000504329|uniprotkb:P22627|uniprotkb:A8K064|uniprotkb:Q9UC98|uniprotkb:Q9UDJ2|uniprotkb:A0A024RA27|uniprotkb:A0A024RA61 psi-mi:kmt5a_human(display_long)|uniprotkb:KMT5A(gene name)|psi-mi:KMT5A(display_short)|uniprotkb:H4-K20-HMTase KMT5A(gene name synonym)|uniprotkb:Histone-lysine N-methyltransferase KMT5A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 5A(gene name synonym)|uniprotkb:Lysine-specific methylase 5A(gene name synonym)|uniprotkb:PR/SET domain-containing protein 07(gene name synonym)|uniprotkb:PRSET7(gene name synonym)|uniprotkb:SET domain-containing protein 8(gene name synonym)|uniprotkb:SET07(gene name synonym)|uniprotkb:SET8(gene name synonym)|uniprotkb:SETD8(gene name synonym) psi-mi:roa2_human(display_long)|uniprotkb:HNRNPA2B1(gene name)|psi-mi:HNRNPA2B1(display_short)|uniprotkb:HNRPA2B1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484537|imex:IM-26985-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065115.3|dip:DIP-39133N|refseq:NP_001311433.1|refseq:NP_001311434.1|refseq:NP_001311435.1|mint:Q9NQR1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR016858(Histone H4-K20 methyltransferase)|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:4IJ8|rcsb pdb:5HQ2|rcsb pdb:5T5G|rcsb pdb:5TEG|rcsb pdb:5TH7|rcsb pdb:5V2N|rcsb pdb:5W1Y|rcsb pdb:6BOZ|rcsb pdb:7D1Z|rcsb pdb:7D20|reactome:R-HSA-2299718|reactome:R-HSA-3214841|reactome:R-HSA-6804760 go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|ensembl:ENST00000679001(transcript)|go:"GO:0016363"(nuclear matrix)|go:"GO:0031053"(primary miRNA processing)|go:"GO:0035198"(miRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0044806"(G-quadruplex DNA unwinding)|go:"GO:0050658"(RNA transport)|ensembl:ENST00000679021(transcript)|go:"GO:0070062"(extracellular exosome)|ensembl:ENST00000679123(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:1904358"(positive regulation of telomere maintenance via telomere lengthening)|go:"GO:1905663"(positive regulation of telomerase RNA reverse transcriptase activity)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|go:"GO:1990428"(miRNA transport)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034486|interpro:IPR034489|interpro:IPR035979|mint:P22626|rcsb pdb:1X4B|rcsb pdb:5EN1|rcsb pdb:5HO4|rcsb pdb:5WWE|rcsb pdb:5WWF|rcsb pdb:5WWG|rcsb pdb:6WPQ|rcsb pdb:6WQK|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-8950505|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|ensembl:ENSG00000122566(gene)|ensembl:ENST00000354667(transcript)|ensembl:ENST00000356674(transcript)|ensembl:ENST00000360787(transcript)|ensembl:ENST00000676746(transcript)|ensembl:ENST00000678675(transcript)|refseq:NP_002128.1|refseq:NP_112533.1|dip:DIP-32877N|refseq:XP_005249786.1|refseq:XP_016867598.1|refseq:XP_016867599.1 - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/0hb5/U7CI+EUSMe0fB1JfXa5zo9606 rogid:N2NeJVio9eYQULNcdE1KXtd2KPw9606 rigid:LNNwlKezZncfL7+m45iaGnD72c0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQR1 uniprotkb:P05204 intact:EBI-1268946|uniprotkb:Q86W83|uniprotkb:Q8TD09|uniprotkb:A8K9D0 intact:EBI-1758689|uniprotkb:Q0VGD5|uniprotkb:Q6FGI5|uniprotkb:Q96C64|ensembl:ENSP00000355228|ensembl:ENSP00000481160 psi-mi:kmt5a_human(display_long)|uniprotkb:KMT5A(gene name)|psi-mi:KMT5A(display_short)|uniprotkb:H4-K20-HMTase KMT5A(gene name synonym)|uniprotkb:Histone-lysine N-methyltransferase KMT5A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 5A(gene name synonym)|uniprotkb:Lysine-specific methylase 5A(gene name synonym)|uniprotkb:PR/SET domain-containing protein 07(gene name synonym)|uniprotkb:PRSET7(gene name synonym)|uniprotkb:SET domain-containing protein 8(gene name synonym)|uniprotkb:SET07(gene name synonym)|uniprotkb:SET8(gene name synonym)|uniprotkb:SETD8(gene name synonym) psi-mi:hmgn2_human(display_long)|uniprotkb:HMGN2(gene name)|psi-mi:HMGN2(display_short)|uniprotkb:HMG17(gene name synonym)|uniprotkb:High mobility group nucleosome-binding domain-containing protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484537|imex:IM-26985-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065115.3|dip:DIP-39133N|refseq:NP_001311433.1|refseq:NP_001311434.1|refseq:NP_001311435.1|mint:Q9NQR1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR016858(Histone H4-K20 methyltransferase)|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:4IJ8|rcsb pdb:5HQ2|rcsb pdb:5T5G|rcsb pdb:5TEG|rcsb pdb:5TH7|rcsb pdb:5V2N|rcsb pdb:5W1Y|rcsb pdb:6BOZ|rcsb pdb:7D1Z|rcsb pdb:7D20|reactome:R-HSA-2299718|reactome:R-HSA-3214841|reactome:R-HSA-6804760 refseq:NP_005508.1|ensembl:ENSG00000198830(gene)|ensembl:ENST00000361427(transcript)|ensembl:ENST00000619352(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000079(High mobility group protein HMG14 and HMG17)|mint:P05204 - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/0hb5/U7CI+EUSMe0fB1JfXa5zo9606 rogid:j8Khsp7BUJh0L9SicpVNR8LP6ZU9606 rigid:LNNwlKezZncfL7+m45iaGnD72c0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQR1 uniprotkb:P61353 intact:EBI-1268946|uniprotkb:Q86W83|uniprotkb:Q8TD09|uniprotkb:A8K9D0 intact:EBI-352760|uniprotkb:P08526|uniprotkb:Q4G0A9|ensembl:ENSP00000253788|ensembl:ENSP00000464813|ensembl:ENSP00000467587 psi-mi:kmt5a_human(display_long)|uniprotkb:KMT5A(gene name)|psi-mi:KMT5A(display_short)|uniprotkb:H4-K20-HMTase KMT5A(gene name synonym)|uniprotkb:Histone-lysine N-methyltransferase KMT5A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 5A(gene name synonym)|uniprotkb:Lysine-specific methylase 5A(gene name synonym)|uniprotkb:PR/SET domain-containing protein 07(gene name synonym)|uniprotkb:PRSET7(gene name synonym)|uniprotkb:SET domain-containing protein 8(gene name synonym)|uniprotkb:SET07(gene name synonym)|uniprotkb:SET8(gene name synonym)|uniprotkb:SETD8(gene name synonym) psi-mi:rl27_human(display_long)|uniprotkb:RPL27(gene name)|psi-mi:RPL27(display_short)|uniprotkb:Large ribosomal subunit protein eL27(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484537|imex:IM-26985-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065115.3|dip:DIP-39133N|refseq:NP_001311433.1|refseq:NP_001311434.1|refseq:NP_001311435.1|mint:Q9NQR1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR016858(Histone H4-K20 methyltransferase)|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:4IJ8|rcsb pdb:5HQ2|rcsb pdb:5T5G|rcsb pdb:5TEG|rcsb pdb:5TH7|rcsb pdb:5V2N|rcsb pdb:5W1Y|rcsb pdb:6BOZ|rcsb pdb:7D1Z|rcsb pdb:7D20|reactome:R-HSA-2299718|reactome:R-HSA-3214841|reactome:R-HSA-6804760 rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OLF|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_000979.1|ensembl:ENSG00000131469(gene)|ensembl:ENST00000253788(transcript)|ensembl:ENST00000589037(transcript)|ensembl:ENST00000589913(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|go:"GO:0070062"(extracellular exosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:1904044"(response to aldosterone)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001141(Ribosomal protein L27e)|interpro:IPR005824(KOW)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR018262|interpro:IPR038655|interpro:IPR041991|mint:P61353|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/0hb5/U7CI+EUSMe0fB1JfXa5zo9606 rogid:TLWbAcdRKUb2ijDYjSUa1sbixis9606 rigid:LNNwlKezZncfL7+m45iaGnD72c0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQR1 uniprotkb:P62917 intact:EBI-1268946|uniprotkb:Q86W83|uniprotkb:Q8TD09|uniprotkb:A8K9D0 intact:EBI-438527|ensembl:ENSP00000262584|ensembl:ENSP00000378378|ensembl:ENSP00000433464|uniprotkb:P25120|uniprotkb:Q567Q7|uniprotkb:Q969V7|uniprotkb:Q9BWQ9|uniprotkb:A8K094|uniprotkb:D3DWN2 psi-mi:kmt5a_human(display_long)|uniprotkb:KMT5A(gene name)|psi-mi:KMT5A(display_short)|uniprotkb:H4-K20-HMTase KMT5A(gene name synonym)|uniprotkb:Histone-lysine N-methyltransferase KMT5A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 5A(gene name synonym)|uniprotkb:Lysine-specific methylase 5A(gene name synonym)|uniprotkb:PR/SET domain-containing protein 07(gene name synonym)|uniprotkb:PRSET7(gene name synonym)|uniprotkb:SET domain-containing protein 8(gene name synonym)|uniprotkb:SET07(gene name synonym)|uniprotkb:SET8(gene name synonym)|uniprotkb:SETD8(gene name synonym) psi-mi:rl8_human(display_long)|uniprotkb:RPL8(gene name)|psi-mi:RPL8(display_short)|uniprotkb:Large ribosomal subunit protein uL2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484537|imex:IM-26985-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065115.3|dip:DIP-39133N|refseq:NP_001311433.1|refseq:NP_001311434.1|refseq:NP_001311435.1|mint:Q9NQR1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR016858(Histone H4-K20 methyltransferase)|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:4IJ8|rcsb pdb:5HQ2|rcsb pdb:5T5G|rcsb pdb:5TEG|rcsb pdb:5TH7|rcsb pdb:5V2N|rcsb pdb:5W1Y|rcsb pdb:6BOZ|rcsb pdb:7D1Z|rcsb pdb:7D20|reactome:R-HSA-2299718|reactome:R-HSA-3214841|reactome:R-HSA-6804760 rcsb pdb:4CCN|rcsb pdb:4CCO|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:4Y3O|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000161016(gene)|ensembl:ENST00000262584(transcript)|ensembl:ENST00000394920(transcript)|ensembl:ENST00000528957(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0098794"(postsynapse)|interpro:IPR002171(Ribosomal protein L2)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR014726(Ribosomal protein L2, domain 3)|interpro:IPR022666|interpro:IPR022669|interpro:IPR022671|interpro:IPR023672|mint:P62917|rcsb pdb:4CCM|refseq:NP_000964.1|refseq:NP_150644.1|refseq:NP_001304700.1|refseq:NP_001304711.1|dip:DIP-37967N - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/0hb5/U7CI+EUSMe0fB1JfXa5zo9606 rogid:+b/ORzdCy/nqFLsKRV9VhIZgdjg9606 rigid:LNNwlKezZncfL7+m45iaGnD72c0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQR1 uniprotkb:P62906 intact:EBI-1268946|uniprotkb:Q86W83|uniprotkb:Q8TD09|uniprotkb:A8K9D0 intact:EBI-356860|uniprotkb:P52859|uniprotkb:P53025|uniprotkb:Q5TZT6|uniprotkb:Q8J013|uniprotkb:B2R801|ensembl:ENSP00000363018 psi-mi:kmt5a_human(display_long)|uniprotkb:KMT5A(gene name)|psi-mi:KMT5A(display_short)|uniprotkb:H4-K20-HMTase KMT5A(gene name synonym)|uniprotkb:Histone-lysine N-methyltransferase KMT5A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 5A(gene name synonym)|uniprotkb:Lysine-specific methylase 5A(gene name synonym)|uniprotkb:PR/SET domain-containing protein 07(gene name synonym)|uniprotkb:PRSET7(gene name synonym)|uniprotkb:SET domain-containing protein 8(gene name synonym)|uniprotkb:SET07(gene name synonym)|uniprotkb:SET8(gene name synonym)|uniprotkb:SETD8(gene name synonym) psi-mi:rl10a_human(display_long)|uniprotkb:RPL10A(gene name)|psi-mi:RPL10A(display_short)|uniprotkb:NEDD6(gene name synonym)|uniprotkb:CSA-19(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 6(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484537|imex:IM-26985-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065115.3|dip:DIP-39133N|refseq:NP_001311433.1|refseq:NP_001311434.1|refseq:NP_001311435.1|mint:Q9NQR1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR016858(Histone H4-K20 methyltransferase)|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:4IJ8|rcsb pdb:5HQ2|rcsb pdb:5T5G|rcsb pdb:5TEG|rcsb pdb:5TH7|rcsb pdb:5V2N|rcsb pdb:5W1Y|rcsb pdb:6BOZ|rcsb pdb:7D1Z|rcsb pdb:7D20|reactome:R-HSA-2299718|reactome:R-HSA-3214841|reactome:R-HSA-6804760 refseq:NP_009035.3|ensembl:ENSG00000198755(gene)|ensembl:ENST00000322203(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002143(Ribosomal protein L1)|interpro:IPR016095(Ribosomal protein L1, 3-layer alpha/beta-sandwich)|interpro:IPR023673|interpro:IPR023674|interpro:IPR028364|mint:P62906|rcsb pdb:4UG0|rcsb pdb:4V6X|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LU8|rcsb pdb:6OLG|rcsb pdb:6QZP|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553 - - comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/0hb5/U7CI+EUSMe0fB1JfXa5zo9606 rogid:wrXKX6vzZ3ovXP3yUoL1/r+NGiw9606 rigid:LNNwlKezZncfL7+m45iaGnD72c0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQR1 uniprotkb:P68431 intact:EBI-1268946|uniprotkb:Q86W83|uniprotkb:Q8TD09|uniprotkb:A8K9D0 intact:EBI-79722|ensembl:ENSP00000352252|ensembl:ENSP00000358160|ensembl:ENSP00000366999|ensembl:ENSP00000480826|ensembl:ENSP00000482271|ensembl:ENSP00000483283|ensembl:ENSP00000484095|ensembl:ENSP00000484638|ensembl:ENSP00000484658|ensembl:ENSP00000484841|ensembl:ENSP00000489282|intact:EBI-1560041|uniprotkb:A0PJT7|uniprotkb:P02295|uniprotkb:P02296|uniprotkb:P16106|uniprotkb:Q6ISV8|uniprotkb:Q6NWP8|uniprotkb:Q6NWP9|uniprotkb:Q6NXU4|uniprotkb:Q71DJ3|uniprotkb:Q93081|uniprotkb:A5PLR1 psi-mi:kmt5a_human(display_long)|uniprotkb:KMT5A(gene name)|psi-mi:KMT5A(display_short)|uniprotkb:H4-K20-HMTase KMT5A(gene name synonym)|uniprotkb:Histone-lysine N-methyltransferase KMT5A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 5A(gene name synonym)|uniprotkb:Lysine-specific methylase 5A(gene name synonym)|uniprotkb:PR/SET domain-containing protein 07(gene name synonym)|uniprotkb:PRSET7(gene name synonym)|uniprotkb:SET domain-containing protein 8(gene name synonym)|uniprotkb:SET07(gene name synonym)|uniprotkb:SET8(gene name synonym)|uniprotkb:SETD8(gene name synonym) psi-mi:h31_human(display_long)|uniprotkb:H3FA(gene name synonym)|uniprotkb:H3FL(gene name synonym)|uniprotkb:H3FD(gene name synonym)|uniprotkb:H3FI(gene name synonym)|uniprotkb:H3FH(gene name synonym)|uniprotkb:H3FK(gene name synonym)|uniprotkb:H3FF(gene name synonym)|uniprotkb:H3FJ(gene name synonym)|uniprotkb:H3FB(gene name synonym)|uniprotkb:Histone H3/a(gene name synonym)|uniprotkb:Histone H3/b(gene name synonym)|uniprotkb:Histone H3/c(gene name synonym)|uniprotkb:Histone H3/d(gene name synonym)|uniprotkb:Histone H3/f(gene name synonym)|uniprotkb:Histone H3/h(gene name synonym)|uniprotkb:Histone H3/i(gene name synonym)|uniprotkb:Histone H3/j(gene name synonym)|uniprotkb:Histone H3/k(gene name synonym)|uniprotkb:Histone H3/l(gene name synonym)|uniprotkb:H3C1(gene name)|psi-mi:H3C1(display_short)|uniprotkb:HIST1H3A(gene name synonym)|uniprotkb:H3C2(gene name)|psi-mi:H3C2(display_short)|uniprotkb:HIST1H3B(gene name synonym)|uniprotkb:H3C3(gene name)|psi-mi:H3C3(display_short)|uniprotkb:H3FC HIST1H3C(gene name synonym)|uniprotkb:H3C4(gene name)|psi-mi:H3C4(display_short)|uniprotkb:HIST1H3D(gene name synonym)|uniprotkb:H3C6(gene name)|psi-mi:H3C6(display_short)|uniprotkb:HIST1H3E(gene name synonym)|uniprotkb:H3C7(gene name)|psi-mi:H3C7(display_short)|uniprotkb:HIST1H3F(gene name synonym)|uniprotkb:H3C8(gene name)|psi-mi:H3C8(display_short)|uniprotkb:HIST1H3G(gene name synonym)|uniprotkb:H3C10(gene name)|psi-mi:H3C10(display_short)|uniprotkb:HIST1H3H(gene name synonym)|uniprotkb:H3C11(gene name)|psi-mi:H3C11(display_short)|uniprotkb:HIST1H3I(gene name synonym)|uniprotkb:H3C12(gene name)|psi-mi:H3C12(display_short)|uniprotkb:HIST1H3J(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484537|imex:IM-26985-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065115.3|dip:DIP-39133N|refseq:NP_001311433.1|refseq:NP_001311434.1|refseq:NP_001311435.1|mint:Q9NQR1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR016858(Histone H4-K20 methyltransferase)|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:4IJ8|rcsb pdb:5HQ2|rcsb pdb:5T5G|rcsb pdb:5TEG|rcsb pdb:5TH7|rcsb pdb:5V2N|rcsb pdb:5W1Y|rcsb pdb:6BOZ|rcsb pdb:7D1Z|rcsb pdb:7D20|reactome:R-HSA-2299718|reactome:R-HSA-3214841|reactome:R-HSA-6804760 rcsb pdb:4TN7|rcsb pdb:4U68|rcsb pdb:4UP0|rcsb pdb:4UY4|rcsb pdb:4X3K|rcsb pdb:4Y6L|rcsb pdb:4YHP|rcsb pdb:4YHZ|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z0R|rcsb pdb:4Z2M|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:4QBS|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B31|rcsb pdb:5C11|rcsb pdb:5C13|rcsb pdb:5C3I|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5D6Y|rcsb pdb:5DAH|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5FFV|rcsb pdb:5GH9|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5H6Q|rcsb pdb:5H6R|rcsb pdb:5HJB|rcsb pdb:5HJC|rcsb pdb:5HJD|rcsb pdb:5HYN|rcsb pdb:5IQL|rcsb pdb:5J3V|rcsb pdb:5J9S|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5B2J|rcsb pdb:5JRG|rcsb pdb:5KJH|rcsb pdb:5KJI|rcsb pdb:5KKL|rcsb pdb:5LUG|rcsb pdb:5M5G|rcsb pdb:5MR8|rcsb pdb:5NNC|rcsb pdb:5OY3|rcsb pdb:5SVX|rcsb pdb:5SVY|rcsb pdb:5SZB|rcsb pdb:5SZC|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5T1G|rcsb pdb:5T1I|rcsb pdb:5T8R|rcsb pdb:5TBN|rcsb pdb:5TDR|rcsb pdb:5TDW|rcsb pdb:5U2J|rcsb pdb:5V21|rcsb pdb:5V22|rcsb pdb:5VA6|rcsb pdb:5VAB|rcsb pdb:5VGE|rcsb pdb:5VNB|rcsb pdb:5NND|rcsb pdb:5WLE|rcsb pdb:5WVO|rcsb pdb:5WXG|rcsb pdb:5WXH|rcsb pdb:5WYI|rcsb pdb:5X60|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5XFQ|rcsb pdb:5XFR|rcsb pdb:5XNV|rcsb pdb:5XTZ|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Y20|rcsb pdb:5Y2F|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:6AXJ|rcsb pdb:6AZE|rcsb pdb:6BHD|rcsb pdb:6BHE|rcsb pdb:6BHG|rcsb pdb:6BHH|rcsb pdb:6BHI|rcsb pdb:6D07|rcsb pdb:6D08|rcsb pdb:6E83|rcsb pdb:6E86|rcsb pdb:5WFC|rcsb pdb:6F6D|rcsb pdb:6HTS|rcsb pdb:6IEU|rcsb pdb:6IIS|rcsb pdb:6IIT|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6JXD|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6LS6|rcsb pdb:6LSD|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MIL|rcsb pdb:6MIM|rcsb pdb:6MIN|rcsb pdb:6MIO|rcsb pdb:6MIQ|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6HKT|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2H|rcsb pdb:6V2K|rcsb pdb:6V3N|rcsb pdb:6V41|rcsb pdb:6V92|rcsb pdb:6VIL|rcsb pdb:6WAV|rcsb pdb:6WW4|rcsb pdb:6YIF|rcsb pdb:6YIH|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:6R92|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7KLR|rcsb pdb:7LYC|reactome:R-HSA-1266695|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|ensembl:ENSG00000197153(gene)|ensembl:ENSG00000197409(gene)|ensembl:ENSG00000273983(gene)|ensembl:ENSG00000274750(gene)|ensembl:ENSG00000275379(gene)|ensembl:ENSG00000275714(gene)|ensembl:ENSG00000277775(gene)|ensembl:ENSG00000278828(gene)|ensembl:ENSG00000286522(gene)|ensembl:ENSG00000287080(gene)|ensembl:ENST00000356476(transcript)|ensembl:ENST00000359303(transcript)|ensembl:ENST00000369163(transcript)|ensembl:ENST00000612966(transcript)|ensembl:ENST00000613854(transcript)|ensembl:ENST00000614378(transcript)|ensembl:ENST00000614911(transcript)|ensembl:ENST00000616365(transcript)|ensembl:ENST00000618052(transcript)|ensembl:ENST00000621411(transcript)|ensembl:ENST00000634733(transcript)|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-3247509|reactome:R-HSA-9710421|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060968"(obsolete regulation of gene silencing)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|interpro:IPR009072(Histone-fold)|mint:P68431|rcsb pdb:1CS9|rcsb pdb:1CT6|rcsb pdb:1O9S|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|rcsb pdb:1Q3L|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|rcsb pdb:2B2T|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|rcsb pdb:2B2U|rcsb pdb:2B2V|rcsb pdb:2B2W|rcsb pdb:2C1J|rcsb pdb:2C1N|go:"GO:0016020"(membrane)|rcsb pdb:2CO0|rcsb pdb:2CV5|rcsb pdb:2FSA|rcsb pdb:2KWJ|rcsb pdb:2KWK|rcsb pdb:2L75|rcsb pdb:2LBM|rcsb pdb:2LGG|rcsb pdb:2M0O|reactome:R-HSA-983231|reactome:R-HSA-977225|rcsb pdb:2NDG|rcsb pdb:2OQ6|rcsb pdb:2OT7|rcsb pdb:2OX0|rcsb pdb:2RI7|rcsb pdb:2RR4|rcsb pdb:2UXN|rcsb pdb:2V85|rcsb pdb:2V89|rcsb pdb:2VNF|rcsb pdb:2VPG|rcsb pdb:2X0L|rcsb pdb:3A1B|rcsb pdb:2NDF|rcsb pdb:3AFA|rcsb pdb:3AVR|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3B95|rcsb pdb:3FDT|rcsb pdb:3KMT|rcsb pdb:3KQI|rcsb pdb:3LQI|rcsb pdb:3LQJ|rcsb pdb:3MP1|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O37|rcsb pdb:3QJ6|rcsb pdb:3RIG|rcsb pdb:3RIY|rcsb pdb:3SOU|rcsb pdb:3SOW|rcsb pdb:3U31|rcsb pdb:3U3D|rcsb pdb:3U4S|rcsb pdb:3U5N|rcsb pdb:3U5O|rcsb pdb:3AZK|rcsb pdb:3U5P|rcsb pdb:3UEE|rcsb pdb:3UEF|rcsb pdb:3UII|rcsb pdb:3UIK|rcsb pdb:3V43|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:3ZG6|rcsb pdb:3ZVY|rcsb pdb:4A0J|rcsb pdb:4A0N|rcsb pdb:4A7J|rcsb pdb:3UIG|rcsb pdb:4BD3|rcsb pdb:4C1Q|rcsb pdb:4F4U|rcsb pdb:4F56|rcsb pdb:4FWF|rcsb pdb:4HON|rcsb pdb:4I51|rcsb pdb:4L7X|rcsb pdb:4LK9|rcsb pdb:4LKA|rcsb pdb:4LLB|rcsb pdb:4LXL|rcsb pdb:4N4H|rcsb pdb:4QBQ|rcsb pdb:4QBR|refseq:NP_003520.1|refseq:NP_003521.2|refseq:NP_003522.1|refseq:NP_003523.1|refseq:NP_003524.1|refseq:NP_003525.1|refseq:NP_003526.1|refseq:NP_003527.1|refseq:NP_003528.1|refseq:NP_066298.1|dip:DIP-29371N - - comment:"author score: 27" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/0hb5/U7CI+EUSMe0fB1JfXa5zo9606 rogid:ood0OohxZHuhsWZtO7U7GMc+LwM9606 rigid:LNNwlKezZncfL7+m45iaGnD72c0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQR1 uniprotkb:P61313 intact:EBI-1268946|uniprotkb:Q86W83|uniprotkb:Q8TD09|uniprotkb:A8K9D0 intact:EBI-443462|ensembl:ENSP00000309334|ensembl:ENSP00000346867|ensembl:ENSP00000388529|ensembl:ENSP00000416692|ensembl:ENSP00000483260|ensembl:ENSP00000493759|uniprotkb:Q642I1|uniprotkb:Q9H2E5|uniprotkb:P39030|uniprotkb:P41051|uniprotkb:Q6IPX6|uniprotkb:Q8WYP2|uniprotkb:Q96C44|uniprotkb:Q5U0C0|intact:EBI-2877712 psi-mi:kmt5a_human(display_long)|uniprotkb:KMT5A(gene name)|psi-mi:KMT5A(display_short)|uniprotkb:H4-K20-HMTase KMT5A(gene name synonym)|uniprotkb:Histone-lysine N-methyltransferase KMT5A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 5A(gene name synonym)|uniprotkb:Lysine-specific methylase 5A(gene name synonym)|uniprotkb:PR/SET domain-containing protein 07(gene name synonym)|uniprotkb:PRSET7(gene name synonym)|uniprotkb:SET domain-containing protein 8(gene name synonym)|uniprotkb:SET07(gene name synonym)|uniprotkb:SET8(gene name synonym)|uniprotkb:SETD8(gene name synonym) psi-mi:rl15_human(display_long)|uniprotkb:RPL15(gene name)|psi-mi:RPL15(display_short)|uniprotkb:EC45(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL15(gene name synonym)|uniprotkb:TCBAP0781(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484537|imex:IM-26985-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065115.3|dip:DIP-39133N|refseq:NP_001311433.1|refseq:NP_001311434.1|refseq:NP_001311435.1|mint:Q9NQR1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR016858(Histone H4-K20 methyltransferase)|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:4IJ8|rcsb pdb:5HQ2|rcsb pdb:5T5G|rcsb pdb:5TEG|rcsb pdb:5TH7|rcsb pdb:5V2N|rcsb pdb:5W1Y|rcsb pdb:6BOZ|rcsb pdb:7D1Z|rcsb pdb:7D20|reactome:R-HSA-2299718|reactome:R-HSA-3214841|reactome:R-HSA-6804760 ensembl:ENSG00000174748(gene)|ensembl:ENST00000307839(transcript)|ensembl:ENST00000354811(transcript)|ensembl:ENST00000413699(transcript)|ensembl:ENST00000415719(transcript)|ensembl:ENST00000611050(transcript)|ensembl:ENST00000644185(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031672"(A band)|go:"GO:0045296"(cadherin binding)|go:"GO:0045471"(response to ethanol)|interpro:IPR000439(Ribosomal protein L15e)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR020925|interpro:IPR024794|mint:P61313|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_002939.2|refseq:NP_001240308.1|refseq:NP_001240309.1|refseq:NP_001240311.1|refseq:NP_001240312.1|refseq:NP_001240313.1 - - comment:"author score: 29" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/0hb5/U7CI+EUSMe0fB1JfXa5zo9606 rogid:wllGpJicgC5uwkZV6e4QRwDcrBo9606 rigid:LNNwlKezZncfL7+m45iaGnD72c0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQR1 uniprotkb:P11940 intact:EBI-1268946|uniprotkb:Q86W83|uniprotkb:Q8TD09|uniprotkb:A8K9D0 intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004 psi-mi:kmt5a_human(display_long)|uniprotkb:KMT5A(gene name)|psi-mi:KMT5A(display_short)|uniprotkb:H4-K20-HMTase KMT5A(gene name synonym)|uniprotkb:Histone-lysine N-methyltransferase KMT5A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 5A(gene name synonym)|uniprotkb:Lysine-specific methylase 5A(gene name synonym)|uniprotkb:PR/SET domain-containing protein 07(gene name synonym)|uniprotkb:PRSET7(gene name synonym)|uniprotkb:SET domain-containing protein 8(gene name synonym)|uniprotkb:SET07(gene name synonym)|uniprotkb:SET8(gene name synonym)|uniprotkb:SETD8(gene name synonym) psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484537|imex:IM-26985-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065115.3|dip:DIP-39133N|refseq:NP_001311433.1|refseq:NP_001311434.1|refseq:NP_001311435.1|mint:Q9NQR1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR016858(Histone H4-K20 methyltransferase)|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:4IJ8|rcsb pdb:5HQ2|rcsb pdb:5T5G|rcsb pdb:5TEG|rcsb pdb:5TH7|rcsb pdb:5V2N|rcsb pdb:5W1Y|rcsb pdb:6BOZ|rcsb pdb:7D1Z|rcsb pdb:7D20|reactome:R-HSA-2299718|reactome:R-HSA-3214841|reactome:R-HSA-6804760 interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N - - comment:"author score: 30" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/0hb5/U7CI+EUSMe0fB1JfXa5zo9606 rogid:XudTSPq2h9ckKAc48X88RVafPRU9606 rigid:LNNwlKezZncfL7+m45iaGnD72c0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQR1 uniprotkb:Q8N136 intact:EBI-1268946|uniprotkb:Q86W83|uniprotkb:Q8TD09|uniprotkb:A8K9D0 intact:EBI-6658298|ensembl:ENSP00000311899|uniprotkb:Q8N776|uniprotkb:Q6ZRY1 psi-mi:kmt5a_human(display_long)|uniprotkb:KMT5A(gene name)|psi-mi:KMT5A(display_short)|uniprotkb:H4-K20-HMTase KMT5A(gene name synonym)|uniprotkb:Histone-lysine N-methyltransferase KMT5A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 5A(gene name synonym)|uniprotkb:Lysine-specific methylase 5A(gene name synonym)|uniprotkb:PR/SET domain-containing protein 07(gene name synonym)|uniprotkb:PRSET7(gene name synonym)|uniprotkb:SET domain-containing protein 8(gene name synonym)|uniprotkb:SET07(gene name synonym)|uniprotkb:SET8(gene name synonym)|uniprotkb:SETD8(gene name synonym) psi-mi:daw1_human(display_long)|uniprotkb:DAW1(gene name)|psi-mi:DAW1(display_short)|uniprotkb:Outer row dynein assembly protein 16 homolog(gene name synonym)|uniprotkb:WD repeat-containing protein 69(gene name synonym)|uniprotkb:WDR69(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484537|imex:IM-26985-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065115.3|dip:DIP-39133N|refseq:NP_001311433.1|refseq:NP_001311434.1|refseq:NP_001311435.1|mint:Q9NQR1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR016858(Histone H4-K20 methyltransferase)|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:4IJ8|rcsb pdb:5HQ2|rcsb pdb:5T5G|rcsb pdb:5TEG|rcsb pdb:5TH7|rcsb pdb:5V2N|rcsb pdb:5W1Y|rcsb pdb:6BOZ|rcsb pdb:7D1Z|rcsb pdb:7D20|reactome:R-HSA-2299718|reactome:R-HSA-3214841|reactome:R-HSA-6804760 refseq:NP_001316933.1|ensembl:ENSG00000123977(gene)|ensembl:ENST00000309931(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005929"(cilium)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0036158"(outer dynein arm assembly)|go:"GO:0051649"(establishment of localization in cell)|go:"GO:0090660"(cerebrospinal fluid circulation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q8N136|rcsb pdb:5NNZ|refseq:NP_849143.1 - - comment:"author score: 37" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/0hb5/U7CI+EUSMe0fB1JfXa5zo9606 rogid:EBknC+lRMjWacMXDNr83pNVo/Jk9606 rigid:LNNwlKezZncfL7+m45iaGnD72c0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQR1 uniprotkb:P05109 intact:EBI-1268946|uniprotkb:Q86W83|uniprotkb:Q8TD09|uniprotkb:A8K9D0 intact:EBI-355281|uniprotkb:Q5SY70|uniprotkb:Q9UC92|uniprotkb:Q9UCJ0|uniprotkb:A8K5L3|uniprotkb:Q9UC84|uniprotkb:Q9UCM6|uniprotkb:D3DV37|ensembl:ENSP00000357721|ensembl:ENSP00000357722 psi-mi:kmt5a_human(display_long)|uniprotkb:KMT5A(gene name)|psi-mi:KMT5A(display_short)|uniprotkb:H4-K20-HMTase KMT5A(gene name synonym)|uniprotkb:Histone-lysine N-methyltransferase KMT5A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 5A(gene name synonym)|uniprotkb:Lysine-specific methylase 5A(gene name synonym)|uniprotkb:PR/SET domain-containing protein 07(gene name synonym)|uniprotkb:PRSET7(gene name synonym)|uniprotkb:SET domain-containing protein 8(gene name synonym)|uniprotkb:SET07(gene name synonym)|uniprotkb:SET8(gene name synonym)|uniprotkb:SETD8(gene name synonym) psi-mi:s10a8_human(display_long)|uniprotkb:S100A8(gene name)|psi-mi:S100A8(display_short)|uniprotkb:CAGA(gene name synonym)|uniprotkb:MRP8(gene name synonym)|uniprotkb:CFAG(gene name synonym)|uniprotkb:S100 calcium-binding protein A8(gene name synonym)|uniprotkb:Calgranulin-A(gene name synonym)|uniprotkb:Migration inhibitory factor-related protein 8(gene name synonym)|uniprotkb:Cystic fibrosis antigen(gene name synonym)|uniprotkb:Leukocyte L1 complex light chain(gene name synonym)|uniprotkb:Calprotectin L1L subunit(gene name synonym)|uniprotkb:Urinary stone protein band A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484537|imex:IM-26985-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065115.3|dip:DIP-39133N|refseq:NP_001311433.1|refseq:NP_001311434.1|refseq:NP_001311435.1|mint:Q9NQR1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR016858(Histone H4-K20 methyltransferase)|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:4IJ8|rcsb pdb:5HQ2|rcsb pdb:5T5G|rcsb pdb:5TEG|rcsb pdb:5TH7|rcsb pdb:5V2N|rcsb pdb:5W1Y|rcsb pdb:6BOZ|rcsb pdb:7D1Z|rcsb pdb:7D20|reactome:R-HSA-2299718|reactome:R-HSA-3214841|reactome:R-HSA-6804760 refseq:NP_001306126.1|refseq:NP_001306127.1|refseq:NP_001306130.1|refseq:NP_002955.2|go:"GO:0042060"(wound healing)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045471"(response to ethanol)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070488"(neutrophil aggregation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028474|go:"GO:0035662"(Toll-like receptor 4 binding)|mint:P05109|rcsb pdb:1MR8|rcsb pdb:1XK4|rcsb pdb:4GGF|rcsb pdb:4XJK|rcsb pdb:5HLO|rcsb pdb:5HLV|rcsb pdb:5W1F|rcsb pdb:6DS2|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5668599|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-6799990|ensembl:ENST00000368732(transcript)|ensembl:ENST00000368733(transcript)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002526"(acute inflammatory response)|ensembl:ENSG00000143546(gene)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0002793"(positive regulation of peptide secretion)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010043"(response to zinc ion)|go:"GO:0014002"(astrocyte development)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032119"(sequestering of zinc ion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035425"(autocrine signaling)|dip:DIP-1165N - - comment:"author score: 42" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/0hb5/U7CI+EUSMe0fB1JfXa5zo9606 rogid:3Okfhj8fxclZ0Uo/Fa1Z89qC8Ec9606 rigid:LNNwlKezZncfL7+m45iaGnD72c0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQR1 uniprotkb:P62424 intact:EBI-1268946|uniprotkb:Q86W83|uniprotkb:Q8TD09|uniprotkb:A8K9D0 intact:EBI-354172|uniprotkb:P11518|uniprotkb:Q5T8U4|ensembl:ENSP00000361076|ensembl:ENSP00000487443 psi-mi:kmt5a_human(display_long)|uniprotkb:KMT5A(gene name)|psi-mi:KMT5A(display_short)|uniprotkb:H4-K20-HMTase KMT5A(gene name synonym)|uniprotkb:Histone-lysine N-methyltransferase KMT5A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 5A(gene name synonym)|uniprotkb:Lysine-specific methylase 5A(gene name synonym)|uniprotkb:PR/SET domain-containing protein 07(gene name synonym)|uniprotkb:PRSET7(gene name synonym)|uniprotkb:SET domain-containing protein 8(gene name synonym)|uniprotkb:SET07(gene name synonym)|uniprotkb:SET8(gene name synonym)|uniprotkb:SETD8(gene name synonym) psi-mi:rl7a_human(display_long)|uniprotkb:RPL7A(gene name)|psi-mi:RPL7A(display_short)|uniprotkb:SURF-3(gene name synonym)|uniprotkb:SURF3(gene name synonym)|uniprotkb:Surfeit locus protein 3(gene name synonym)|uniprotkb:PLA-X polypeptide(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484537|imex:IM-26985-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065115.3|dip:DIP-39133N|refseq:NP_001311433.1|refseq:NP_001311434.1|refseq:NP_001311435.1|mint:Q9NQR1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR016858(Histone H4-K20 methyltransferase)|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:4IJ8|rcsb pdb:5HQ2|rcsb pdb:5T5G|rcsb pdb:5TEG|rcsb pdb:5TH7|rcsb pdb:5V2N|rcsb pdb:5W1Y|rcsb pdb:6BOZ|rcsb pdb:7D1Z|rcsb pdb:7D20|reactome:R-HSA-2299718|reactome:R-HSA-3214841|reactome:R-HSA-6804760 refseq:NP_000963.1|dip:DIP-31502N|ensembl:ENSG00000148303(gene)|ensembl:ENSG00000280858(gene)|ensembl:ENST00000323345(transcript)|ensembl:ENST00000630979(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR001921(Ribosomal protein L7A)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|mint:P62424|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|go:"GO:0005634"(nucleus)|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - comment:"author score: 43" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/0hb5/U7CI+EUSMe0fB1JfXa5zo9606 rogid:shPtLmc+oabT/rSwho+tP1iJy4k9606 rigid:LNNwlKezZncfL7+m45iaGnD72c0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQR1 uniprotkb:P42766 intact:EBI-1268946|uniprotkb:Q86W83|uniprotkb:Q8TD09|uniprotkb:A8K9D0 intact:EBI-356819|uniprotkb:Q4VBY5|uniprotkb:Q9BYF4|uniprotkb:Q5JTN5|uniprotkb:Q6IBC7|uniprotkb:Q96QJ7|uniprotkb:A8K4V7|ensembl:ENSP00000259469 psi-mi:kmt5a_human(display_long)|uniprotkb:KMT5A(gene name)|psi-mi:KMT5A(display_short)|uniprotkb:H4-K20-HMTase KMT5A(gene name synonym)|uniprotkb:Histone-lysine N-methyltransferase KMT5A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 5A(gene name synonym)|uniprotkb:Lysine-specific methylase 5A(gene name synonym)|uniprotkb:PR/SET domain-containing protein 07(gene name synonym)|uniprotkb:PRSET7(gene name synonym)|uniprotkb:SET domain-containing protein 8(gene name synonym)|uniprotkb:SET07(gene name synonym)|uniprotkb:SET8(gene name synonym)|uniprotkb:SETD8(gene name synonym) psi-mi:rl35_human(display_long)|uniprotkb:RPL35(gene name)|psi-mi:RPL35(display_short)|uniprotkb:Large ribosomal subunit protein uL29(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484537|imex:IM-26985-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065115.3|dip:DIP-39133N|refseq:NP_001311433.1|refseq:NP_001311434.1|refseq:NP_001311435.1|mint:Q9NQR1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR016858(Histone H4-K20 methyltransferase)|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:4IJ8|rcsb pdb:5HQ2|rcsb pdb:5T5G|rcsb pdb:5TEG|rcsb pdb:5TH7|rcsb pdb:5V2N|rcsb pdb:5W1Y|rcsb pdb:6BOZ|rcsb pdb:7D1Z|rcsb pdb:7D20|reactome:R-HSA-2299718|reactome:R-HSA-3214841|reactome:R-HSA-6804760 refseq:NP_009140.1|ensembl:ENSG00000136942(gene)|ensembl:ENST00000348462(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|interpro:IPR001854(Ribosomal protein L29)|interpro:IPR018254|interpro:IPR036049|mint:P42766|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - comment:"author score: 43" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/0hb5/U7CI+EUSMe0fB1JfXa5zo9606 rogid:jhzt7gCff2vdUb1Ff/VTBF698Pg9606 rigid:LNNwlKezZncfL7+m45iaGnD72c0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQR1 uniprotkb:P05387 intact:EBI-1268946|uniprotkb:Q86W83|uniprotkb:Q8TD09|uniprotkb:A8K9D0 intact:EBI-352813|ensembl:ENSP00000322419|ensembl:ENSP00000431240|uniprotkb:Q6FG96 psi-mi:kmt5a_human(display_long)|uniprotkb:KMT5A(gene name)|psi-mi:KMT5A(display_short)|uniprotkb:H4-K20-HMTase KMT5A(gene name synonym)|uniprotkb:Histone-lysine N-methyltransferase KMT5A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 5A(gene name synonym)|uniprotkb:Lysine-specific methylase 5A(gene name synonym)|uniprotkb:PR/SET domain-containing protein 07(gene name synonym)|uniprotkb:PRSET7(gene name synonym)|uniprotkb:SET domain-containing protein 8(gene name synonym)|uniprotkb:SET07(gene name synonym)|uniprotkb:SET8(gene name synonym)|uniprotkb:SETD8(gene name synonym) psi-mi:rla2_human(display_long)|uniprotkb:RPLP2(gene name)|psi-mi:RPLP2(display_short)|uniprotkb:RPP2(gene name synonym)|uniprotkb:D11S2243E(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-44(gene name synonym)|uniprotkb:Large ribosomal subunit protein P2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484537|imex:IM-26985-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065115.3|dip:DIP-39133N|refseq:NP_001311433.1|refseq:NP_001311434.1|refseq:NP_001311435.1|mint:Q9NQR1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR016858(Histone H4-K20 methyltransferase)|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:4IJ8|rcsb pdb:5HQ2|rcsb pdb:5T5G|rcsb pdb:5TEG|rcsb pdb:5TH7|rcsb pdb:5V2N|rcsb pdb:5W1Y|rcsb pdb:6BOZ|rcsb pdb:7D1Z|rcsb pdb:7D20|reactome:R-HSA-2299718|reactome:R-HSA-3214841|reactome:R-HSA-6804760 ensembl:ENSG00000177600(gene)|ensembl:ENST00000321153(transcript)|ensembl:ENST00000530797(transcript)|go:"GO:0002182"(cytoplasmic translational elongation)|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-72689|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR027534|interpro:IPR038716|interpro:IPR044076|mint:P05387|rcsb pdb:1S4J|rcsb pdb:2JDL|rcsb pdb:2LBF|rcsb pdb:2W1O|rcsb pdb:4BEH|rcsb pdb:4V6X|rcsb pdb:5DDZ|rcsb pdb:5GU4|go:"GO:0003735"(structural constituent of ribosome)|reactome:R-HSA-156827|reactome:R-HSA-156902|refseq:NP_000995.1 - - comment:"author score: 46" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/0hb5/U7CI+EUSMe0fB1JfXa5zo9606 rogid:IBI+x82JJYg66MPhGKw1/pI/bQA9606 rigid:LNNwlKezZncfL7+m45iaGnD72c0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQR1 uniprotkb:P06702 intact:EBI-1268946|uniprotkb:Q86W83|uniprotkb:Q8TD09|uniprotkb:A8K9D0 intact:EBI-1055001|uniprotkb:Q6FGA1|uniprotkb:Q9NYM0|uniprotkb:Q9UCJ1|uniprotkb:D3DV36|ensembl:ENSP00000357727 psi-mi:kmt5a_human(display_long)|uniprotkb:KMT5A(gene name)|psi-mi:KMT5A(display_short)|uniprotkb:H4-K20-HMTase KMT5A(gene name synonym)|uniprotkb:Histone-lysine N-methyltransferase KMT5A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 5A(gene name synonym)|uniprotkb:Lysine-specific methylase 5A(gene name synonym)|uniprotkb:PR/SET domain-containing protein 07(gene name synonym)|uniprotkb:PRSET7(gene name synonym)|uniprotkb:SET domain-containing protein 8(gene name synonym)|uniprotkb:SET07(gene name synonym)|uniprotkb:SET8(gene name synonym)|uniprotkb:SETD8(gene name synonym) psi-mi:s10a9_human(display_long)|uniprotkb:S100 calcium-binding protein A9(gene name synonym)|uniprotkb:Calgranulin-B(gene name synonym)|uniprotkb:Migration inhibitory factor-related protein 14(gene name synonym)|uniprotkb:Leukocyte L1 complex heavy chain(gene name synonym)|uniprotkb:Calprotectin L1H subunit(gene name synonym)|uniprotkb:S100A9(gene name)|psi-mi:S100A9(display_short)|uniprotkb:CAGB(gene name synonym)|uniprotkb:CFAG(gene name synonym)|uniprotkb:MRP14(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484537|imex:IM-26985-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065115.3|dip:DIP-39133N|refseq:NP_001311433.1|refseq:NP_001311434.1|refseq:NP_001311435.1|mint:Q9NQR1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR016858(Histone H4-K20 methyltransferase)|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:4IJ8|rcsb pdb:5HQ2|rcsb pdb:5T5G|rcsb pdb:5TEG|rcsb pdb:5TH7|rcsb pdb:5V2N|rcsb pdb:5W1Y|rcsb pdb:6BOZ|rcsb pdb:7D1Z|rcsb pdb:7D20|reactome:R-HSA-2299718|reactome:R-HSA-3214841|reactome:R-HSA-6804760 refseq:NP_002956.1|rcsb pdb:1XK4|rcsb pdb:4GGF|rcsb pdb:4XJK|rcsb pdb:5I8N|rcsb pdb:5W1F|rcsb pdb:6DS2|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5668599|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-6799990|ensembl:ENSG00000163220(gene)|ensembl:ENST00000368738(transcript)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035662"(Toll-like receptor 4 binding)|go:"GO:0035821"(modulation of process of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0045113"(regulation of integrin biosynthetic process)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070488"(neutrophil aggregation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|mint:P06702|rcsb pdb:1IRJ|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016209"(antioxidant activity)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0030054"(cell junction)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032119"(sequestering of zinc ion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035425"(autocrine signaling)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|dip:DIP-1166N - - comment:"author score: 48" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/0hb5/U7CI+EUSMe0fB1JfXa5zo9606 rogid:IGnX4DSnv8xMr5pY4T7X7vYos5A9606 rigid:LNNwlKezZncfL7+m45iaGnD72c0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQR1 uniprotkb:Q9UNX3 intact:EBI-1268946|uniprotkb:Q86W83|uniprotkb:Q8TD09|uniprotkb:A8K9D0 intact:EBI-2949703|ensembl:ENSP00000265100|ensembl:ENSP00000428177|ensembl:ENSP00000428223|ensembl:ENSP00000430147|uniprotkb:B3KY82|uniprotkb:D3DQM0 psi-mi:kmt5a_human(display_long)|uniprotkb:KMT5A(gene name)|psi-mi:KMT5A(display_short)|uniprotkb:H4-K20-HMTase KMT5A(gene name synonym)|uniprotkb:Histone-lysine N-methyltransferase KMT5A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 5A(gene name synonym)|uniprotkb:Lysine-specific methylase 5A(gene name synonym)|uniprotkb:PR/SET domain-containing protein 07(gene name synonym)|uniprotkb:PRSET7(gene name synonym)|uniprotkb:SET domain-containing protein 8(gene name synonym)|uniprotkb:SET07(gene name synonym)|uniprotkb:SET8(gene name synonym)|uniprotkb:SETD8(gene name synonym) psi-mi:rl26l_human(display_long)|uniprotkb:RPL26L1(gene name)|psi-mi:RPL26L1(display_short)|uniprotkb:RPL26P1(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL24-like 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484537|imex:IM-26985-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065115.3|dip:DIP-39133N|refseq:NP_001311433.1|refseq:NP_001311434.1|refseq:NP_001311435.1|mint:Q9NQR1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR016858(Histone H4-K20 methyltransferase)|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:4IJ8|rcsb pdb:5HQ2|rcsb pdb:5T5G|rcsb pdb:5TEG|rcsb pdb:5TH7|rcsb pdb:5V2N|rcsb pdb:5W1Y|rcsb pdb:6BOZ|rcsb pdb:7D1Z|rcsb pdb:7D20|reactome:R-HSA-2299718|reactome:R-HSA-3214841|reactome:R-HSA-6804760 ensembl:ENSG00000037241(gene)|ensembl:ENST00000265100(transcript)|ensembl:ENST00000519239(transcript)|ensembl:ENST00000519974(transcript)|ensembl:ENST00000521476(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005756(Ribosomal protein L26, eukaryotic/archaeal)|interpro:IPR005824(KOW)|interpro:IPR005825(Ribosomal protein L24/L26, conserved site)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041988|mint:Q9UNX3|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-2408557|refseq:NP_057177.1|refseq:XP_011532867.1|refseq:NP_001304909.1|refseq:NP_001304910.1|refseq:NP_001304911.1|refseq:XP_016865008.1|refseq:XP_016865009.1 - - comment:"author score: 49" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/0hb5/U7CI+EUSMe0fB1JfXa5zo9606 rogid:dny/DWK4MvWD3FUJvW5+KGI3iJI9606 rigid:LNNwlKezZncfL7+m45iaGnD72c0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQR1 uniprotkb:P31151 intact:EBI-1268946|uniprotkb:Q86W83|uniprotkb:Q8TD09|uniprotkb:A8K9D0 intact:EBI-357520|uniprotkb:Q6FGE3|uniprotkb:Q5SY67|uniprotkb:Q9H1E2|ensembl:ENSP00000357711|ensembl:ENSP00000357712 psi-mi:kmt5a_human(display_long)|uniprotkb:KMT5A(gene name)|psi-mi:KMT5A(display_short)|uniprotkb:H4-K20-HMTase KMT5A(gene name synonym)|uniprotkb:Histone-lysine N-methyltransferase KMT5A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 5A(gene name synonym)|uniprotkb:Lysine-specific methylase 5A(gene name synonym)|uniprotkb:PR/SET domain-containing protein 07(gene name synonym)|uniprotkb:PRSET7(gene name synonym)|uniprotkb:SET domain-containing protein 8(gene name synonym)|uniprotkb:SET07(gene name synonym)|uniprotkb:SET8(gene name synonym)|uniprotkb:SETD8(gene name synonym) psi-mi:s10a7_human(display_long)|uniprotkb:S100A7(gene name)|psi-mi:S100A7(display_short)|uniprotkb:PSOR1(gene name synonym)|uniprotkb:S100A7C(gene name synonym)|uniprotkb:S100 calcium-binding protein A7(gene name synonym)|uniprotkb:Psoriasin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484537|imex:IM-26985-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065115.3|dip:DIP-39133N|refseq:NP_001311433.1|refseq:NP_001311434.1|refseq:NP_001311435.1|mint:Q9NQR1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR016858(Histone H4-K20 methyltransferase)|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:4IJ8|rcsb pdb:5HQ2|rcsb pdb:5T5G|rcsb pdb:5TEG|rcsb pdb:5TH7|rcsb pdb:5V2N|rcsb pdb:5W1Y|rcsb pdb:6BOZ|rcsb pdb:7D1Z|rcsb pdb:7D20|reactome:R-HSA-2299718|reactome:R-HSA-3214841|reactome:R-HSA-6804760 ensembl:ENSG00000143556(gene)|ensembl:ENST00000368722(transcript)|ensembl:ENST00000368723(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0001525"(angiogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008544"(epidermis development)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0045087"(innate immune response)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051238"(sequestering of metal ion)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071624"(positive regulation of granulocyte chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028477|interpro:IPR034325|mint:P31151|rcsb pdb:1PSR|rcsb pdb:2PSR|rcsb pdb:2WND|rcsb pdb:2WOR|rcsb pdb:2WOS|rcsb pdb:3PSR|rcsb pdb:4AQJ|reactome:R-HSA-6798695|reactome:R-HSA-6799990|refseq:NP_002954.2 - - comment:"author score: 52" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/0hb5/U7CI+EUSMe0fB1JfXa5zo9606 rogid:/v8+XQ7rCMTYzq9k/KqjcSm/G0A9606 rigid:LNNwlKezZncfL7+m45iaGnD72c0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQR1 uniprotkb:Q9UKM9 intact:EBI-1268946|uniprotkb:Q86W83|uniprotkb:Q8TD09|uniprotkb:A8K9D0 intact:EBI-714796|uniprotkb:Q14621|uniprotkb:Q2M365|uniprotkb:Q5QPL8|uniprotkb:Q9BQX6|uniprotkb:Q9UJE3|ensembl:ENSP00000246194 psi-mi:kmt5a_human(display_long)|uniprotkb:KMT5A(gene name)|psi-mi:KMT5A(display_short)|uniprotkb:H4-K20-HMTase KMT5A(gene name synonym)|uniprotkb:Histone-lysine N-methyltransferase KMT5A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 5A(gene name synonym)|uniprotkb:Lysine-specific methylase 5A(gene name synonym)|uniprotkb:PR/SET domain-containing protein 07(gene name synonym)|uniprotkb:PRSET7(gene name synonym)|uniprotkb:SET domain-containing protein 8(gene name synonym)|uniprotkb:SET07(gene name synonym)|uniprotkb:SET8(gene name synonym)|uniprotkb:SETD8(gene name synonym) psi-mi:raly_human(display_long)|uniprotkb:hnRNP associated with lethal yellow protein homolog(gene name synonym)|uniprotkb:Autoantigen p542(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein C-like 2(gene name synonym)|uniprotkb:RALY(gene name)|psi-mi:RALY(display_short)|uniprotkb:P542(gene name synonym)|uniprotkb:HNRPCL2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484537|imex:IM-26985-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065115.3|dip:DIP-39133N|refseq:NP_001311433.1|refseq:NP_001311434.1|refseq:NP_001311435.1|mint:Q9NQR1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR016858(Histone H4-K20 methyltransferase)|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:4IJ8|rcsb pdb:5HQ2|rcsb pdb:5T5G|rcsb pdb:5TEG|rcsb pdb:5TH7|rcsb pdb:5V2N|rcsb pdb:5W1Y|rcsb pdb:6BOZ|rcsb pdb:7D1Z|rcsb pdb:7D20|reactome:R-HSA-2299718|reactome:R-HSA-3214841|reactome:R-HSA-6804760 refseq:XP_011526996.1|refseq:XP_011526997.1|ensembl:ENSG00000125970(gene)|ensembl:ENST00000246194(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1903506"(regulation of nucleic acid-templated transcription)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017347(Heterogeneous nuclear ribonucleoprotein C, Raly)|interpro:IPR034502|interpro:IPR035979|mint:Q9UKM9|rcsb pdb:1WF1|refseq:NP_031393.2|refseq:NP_057951.1|refseq:XP_005260391.1|refseq:XP_005260393.1|refseq:XP_016883220.1 - - comment:"author score: 56" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/0hb5/U7CI+EUSMe0fB1JfXa5zo9606 rogid:3hd0n2UW0FSRNvSJa2mqflVeorc9606 rigid:LNNwlKezZncfL7+m45iaGnD72c0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQR1 uniprotkb:P83916 intact:EBI-1268946|uniprotkb:Q86W83|uniprotkb:Q8TD09|uniprotkb:A8K9D0 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 psi-mi:kmt5a_human(display_long)|uniprotkb:KMT5A(gene name)|psi-mi:KMT5A(display_short)|uniprotkb:H4-K20-HMTase KMT5A(gene name synonym)|uniprotkb:Histone-lysine N-methyltransferase KMT5A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 5A(gene name synonym)|uniprotkb:Lysine-specific methylase 5A(gene name synonym)|uniprotkb:PR/SET domain-containing protein 07(gene name synonym)|uniprotkb:PRSET7(gene name synonym)|uniprotkb:SET domain-containing protein 8(gene name synonym)|uniprotkb:SET07(gene name synonym)|uniprotkb:SET8(gene name synonym)|uniprotkb:SETD8(gene name synonym) psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484537|imex:IM-26985-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065115.3|dip:DIP-39133N|refseq:NP_001311433.1|refseq:NP_001311434.1|refseq:NP_001311435.1|mint:Q9NQR1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR016858(Histone H4-K20 methyltransferase)|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:4IJ8|rcsb pdb:5HQ2|rcsb pdb:5T5G|rcsb pdb:5TEG|rcsb pdb:5TH7|rcsb pdb:5V2N|rcsb pdb:5W1Y|rcsb pdb:6BOZ|rcsb pdb:7D1Z|rcsb pdb:7D20|reactome:R-HSA-2299718|reactome:R-HSA-3214841|reactome:R-HSA-6804760 ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N - - comment:"author score: 69" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/0hb5/U7CI+EUSMe0fB1JfXa5zo9606 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rigid:LNNwlKezZncfL7+m45iaGnD72c0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQR1 uniprotkb:Q9Y3U8 intact:EBI-1268946|uniprotkb:Q86W83|uniprotkb:Q8TD09|uniprotkb:A8K9D0 intact:EBI-1057689|uniprotkb:Q6FIG1|uniprotkb:Q9UQF6|uniprotkb:B2R4Y1|uniprotkb:D6W634|ensembl:ENSP00000252543|ensembl:ENSP00000378081|ensembl:ENSP00000462609|ensembl:ENSP00000464342 psi-mi:kmt5a_human(display_long)|uniprotkb:KMT5A(gene name)|psi-mi:KMT5A(display_short)|uniprotkb:H4-K20-HMTase KMT5A(gene name synonym)|uniprotkb:Histone-lysine N-methyltransferase KMT5A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 5A(gene name synonym)|uniprotkb:Lysine-specific methylase 5A(gene name synonym)|uniprotkb:PR/SET domain-containing protein 07(gene name synonym)|uniprotkb:PRSET7(gene name synonym)|uniprotkb:SET domain-containing protein 8(gene name synonym)|uniprotkb:SET07(gene name synonym)|uniprotkb:SET8(gene name synonym)|uniprotkb:SETD8(gene name synonym) psi-mi:rl36_human(display_long)|uniprotkb:RPL36(gene name)|psi-mi:RPL36(display_short)|uniprotkb:Large ribosomal subunit protein eL36(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484537|imex:IM-26985-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065115.3|dip:DIP-39133N|refseq:NP_001311433.1|refseq:NP_001311434.1|refseq:NP_001311435.1|mint:Q9NQR1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR016858(Histone H4-K20 methyltransferase)|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:4IJ8|rcsb pdb:5HQ2|rcsb pdb:5T5G|rcsb pdb:5TEG|rcsb pdb:5TH7|rcsb pdb:5V2N|rcsb pdb:5W1Y|rcsb pdb:6BOZ|rcsb pdb:7D1Z|rcsb pdb:7D20|reactome:R-HSA-2299718|reactome:R-HSA-3214841|reactome:R-HSA-6804760 refseq:NP_056229.2|refseq:NP_378669.1|reactome:R-HSA-975957|mint:Q9Y3U8|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|interpro:IPR038097|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|rcsb pdb:6Y6X|ensembl:ENSG00000130255(gene)|ensembl:ENST00000347512(transcript)|ensembl:ENST00000394580(transcript)|ensembl:ENST00000577222(transcript)|ensembl:ENST00000579649(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR000509(Ribosomal protein L36e) - - comment:"author score: 78" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/0hb5/U7CI+EUSMe0fB1JfXa5zo9606 rogid:lRlRMF2jV/UHr4SX95SSCFIEV+s9606 rigid:LNNwlKezZncfL7+m45iaGnD72c0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NQR1 uniprotkb:P0C0S8 intact:EBI-1268946|uniprotkb:Q86W83|uniprotkb:Q8TD09|uniprotkb:A8K9D0 intact:EBI-1390628|uniprotkb:P02261|uniprotkb:Q2M1R2|uniprotkb:Q76PA6|intact:EBI-1642354|ensembl:ENSP00000351589|ensembl:ENSP00000352119|ensembl:ENSP00000352627|ensembl:ENSP00000482431|ensembl:ENSP00000482538 psi-mi:kmt5a_human(display_long)|uniprotkb:KMT5A(gene name)|psi-mi:KMT5A(display_short)|uniprotkb:H4-K20-HMTase KMT5A(gene name synonym)|uniprotkb:Histone-lysine N-methyltransferase KMT5A(gene name synonym)|uniprotkb:Lysine N-methyltransferase 5A(gene name synonym)|uniprotkb:Lysine-specific methylase 5A(gene name synonym)|uniprotkb:PR/SET domain-containing protein 07(gene name synonym)|uniprotkb:PRSET7(gene name synonym)|uniprotkb:SET domain-containing protein 8(gene name synonym)|uniprotkb:SET07(gene name synonym)|uniprotkb:SET8(gene name synonym)|uniprotkb:SETD8(gene name synonym) psi-mi:h2a1_human(display_long)|uniprotkb:H2AC11(gene name)|psi-mi:H2AC11(display_short)|uniprotkb:H2AC13(gene name)|psi-mi:H2AC13(display_short)|uniprotkb:H2AC15(gene name)|psi-mi:H2AC15(display_short)|uniprotkb:H2AC16(gene name)|psi-mi:H2AC16(display_short)|uniprotkb:H2AC17(gene name)|psi-mi:H2AC17(display_short)|uniprotkb:H2AFC(gene name synonym)|uniprotkb:H2AFD(gene name synonym)|uniprotkb:H2AFI(gene name synonym)|uniprotkb:H2AFN(gene name synonym)|uniprotkb:H2AFP(gene name synonym)|uniprotkb:HIST1H2AG(gene name synonym)|uniprotkb:HIST1H2AI(gene name synonym)|uniprotkb:HIST1H2AK(gene name synonym)|uniprotkb:HIST1H2AL(gene name synonym)|uniprotkb:HIST1H2AM(gene name synonym)|uniprotkb:Histone H2A/ptl(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484537|imex:IM-26985-57 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065115.3|dip:DIP-39133N|refseq:NP_001311433.1|refseq:NP_001311434.1|refseq:NP_001311435.1|mint:Q9NQR1|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051301"(cell division)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR016858(Histone H4-K20 methyltransferase)|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:4IJ8|rcsb pdb:5HQ2|rcsb pdb:5T5G|rcsb pdb:5TEG|rcsb pdb:5TH7|rcsb pdb:5V2N|rcsb pdb:5W1Y|rcsb pdb:6BOZ|rcsb pdb:7D1Z|rcsb pdb:7D20|reactome:R-HSA-2299718|reactome:R-HSA-3214841|reactome:R-HSA-6804760 ensembl:ENSG00000196747(gene)|ensembl:ENSG00000196787(gene)|ensembl:ENSG00000275221(gene)|ensembl:ENSG00000276903(gene)|ensembl:ENSG00000278677(gene)|refseq:NP_003500.1|refseq:NP_003501.1|refseq:NP_003502.1|refseq:NP_003505.1|refseq:NP_066408.1|dip:DIP-39638N|ensembl:ENST00000358739(transcript)|ensembl:ENST00000359193(transcript)|ensembl:ENST00000359611(transcript)|ensembl:ENST00000613174(transcript)|ensembl:ENST00000618958(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0019899"(enzyme binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P0C0S8|rcsb pdb:4QYL|rcsb pdb:5KGF|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:7JO9|rcsb pdb:7JOA|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - comment:"author score: 92" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/0hb5/U7CI+EUSMe0fB1JfXa5zo9606 rogid:dpZm9c7r9ihR4gW0TZWsVfXAWJ89606 rigid:LNNwlKezZncfL7+m45iaGnD72c0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NZC9 uniprotkb:P27694 intact:EBI-5457961|uniprotkb:A6NEH0|uniprotkb:Q53R00|uniprotkb:Q96AY1|uniprotkb:Q9NXQ5|uniprotkb:Q9UFH3|uniprotkb:Q9UI93|ensembl:ENSP00000349823|ensembl:ENSP00000350940 intact:EBI-621389|ensembl:ENSP00000254719|uniprotkb:Q59ES9|uniprotkb:A8K0Y9 psi-mi:smal1_human(display_long)|uniprotkb:SMARCAL1(gene name)|psi-mi:SMARCAL1(display_short)|uniprotkb:HARP(gene name synonym)|uniprotkb:HepA-related protein(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 1(gene name synonym) psi-mi:rfa1_human(display_long)|uniprotkb:Replication factor A protein 1(gene name synonym)|uniprotkb:Single-stranded DNA-binding protein(gene name synonym)|uniprotkb:RPA1(gene name)|psi-mi:RPA1(display_short)|uniprotkb:REPA1(gene name synonym)|uniprotkb:RPA70(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484762|imex:IM-26985-207 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120679.1|refseq:NP_054859.2|refseq:XP_005246688.1|refseq:XP_005246689.1|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031297"(replication fork processing)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|go:"GO:0070615"|ensembl:ENSG00000138375(gene)|ensembl:ENST00000357276(transcript)|ensembl:ENST00000358207(transcript)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR010003(HepA-related)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR030101|interpro:IPR038718|mint:Q9NZC9|rcsb pdb:4MQV|go:"GO:0090656"(t-circle formation) ensembl:ENSG00000132383(gene)|ensembl:ENST00000254719(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006261"(DNA-dependent DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0016605"(PML body)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0043047"(single-stranded telomeric DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0090734"(site of DNA damage)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|interpro:IPR004365(Nucleic acid binding, OB-fold, tRNA/helicase-type)|interpro:IPR004591(Replication factor-a protein 1 Rpa1)|interpro:IPR007199(Replication factor-A protein 1, N-terminal)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR013955(Replication factor-A, C-terminal)|interpro:IPR031657|go:"GO:0006268"(DNA unwinding involved in DNA replication)|mint:P27694|rcsb pdb:1EWI|rcsb pdb:1FGU|rcsb pdb:1JMC|rcsb pdb:1L1O|rcsb pdb:2B29|rcsb pdb:2B3G|rcsb pdb:4IJH|rcsb pdb:4IJL|rcsb pdb:4IPC|rcsb pdb:4IPD|rcsb pdb:4IPG|rcsb pdb:4IPH|rcsb pdb:4LUO|rcsb pdb:4LUV|rcsb pdb:4LUZ|rcsb pdb:4LW1|rcsb pdb:4LWC|rcsb pdb:4NB3|rcsb pdb:4O0A|rcsb pdb:4R4C|rcsb pdb:4R4I|rcsb pdb:4R4O|rcsb pdb:4R4Q|rcsb pdb:4R4T|rcsb pdb:5E7N|rcsb pdb:5EAY|rcsb pdb:5N85|rcsb pdb:5N8A|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|reactome:R-HSA-3108214|refseq:NP_002936.1|dip:DIP-24189N - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:sUz7fctEmC8ajY7I9H474RGxhag9606 rogid:DRZpMUlGyS0Qa5XFEtx71k0iPig9606 rigid:aTpm6yPvAhExkKldOVDQtslZrg8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NZC9 uniprotkb:P15927 intact:EBI-5457961|uniprotkb:A6NEH0|uniprotkb:Q53R00|uniprotkb:Q96AY1|uniprotkb:Q9NXQ5|uniprotkb:Q9UFH3|uniprotkb:Q9UI93|ensembl:ENSP00000349823|ensembl:ENSP00000350940 intact:EBI-621404|ensembl:ENSP00000363021|uniprotkb:Q52II0|uniprotkb:Q5TEI9|uniprotkb:Q5TEJ5 psi-mi:smal1_human(display_long)|uniprotkb:SMARCAL1(gene name)|psi-mi:SMARCAL1(display_short)|uniprotkb:HARP(gene name synonym)|uniprotkb:HepA-related protein(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 1(gene name synonym) psi-mi:rfa2_human(display_long)|uniprotkb:RPA34(gene name synonym)|uniprotkb:Replication protein A 34 kDa subunit(gene name synonym)|uniprotkb:Replication factor A protein 2(gene name synonym)|uniprotkb:RPA2(gene name)|psi-mi:RPA2(display_short)|uniprotkb:REPA2(gene name synonym)|uniprotkb:RPA32(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484762|imex:IM-26985-207 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120679.1|refseq:NP_054859.2|refseq:XP_005246688.1|refseq:XP_005246689.1|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031297"(replication fork processing)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|go:"GO:0070615"|ensembl:ENSG00000138375(gene)|ensembl:ENST00000357276(transcript)|ensembl:ENST00000358207(transcript)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR010003(HepA-related)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR030101|interpro:IPR038718|mint:Q9NZC9|rcsb pdb:4MQV|go:"GO:0090656"(t-circle formation) rcsb pdb:1L1O|rcsb pdb:1QUQ|rcsb pdb:1Z1D|rcsb pdb:2PI2|rcsb pdb:2PQA|rcsb pdb:2Z6K|rcsb pdb:3KDF|rcsb pdb:4MQV|rcsb pdb:4OU0|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-174437|reactome:R-HSA-176187|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-5358565|reactome:R-HSA-5358606|reactome:R-HSA-5651801|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5685938|reactome:R-HSA-5685942|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-68962|reactome:R-HSA-69166|reactome:R-HSA-69473|reactome:R-HSA-912446|rcsb pdb:1DPU|ensembl:ENSG00000117748(gene)|ensembl:ENST00000373912(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005662"(DNA replication factor A complex)|go:"GO:0006260"(DNA replication)|go:"GO:0006284"(base-excision repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006298"(mismatch repair)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034502"(protein localization to chromosome)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0098505"(G-rich strand telomeric DNA binding)|go:"GO:2000001"(regulation of DNA damage checkpoint)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014646(Replication protein A, subunit RPA32)|interpro:IPR014892(Replication protein A C terminal)|interpro:IPR036388|interpro:IPR036390|interpro:IPR040260|mint:P15927|refseq:NP_001273005.1|refseq:NP_002937.1|refseq:NP_001284487.1|dip:DIP-24187N - - comment:"author score: 37" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:sUz7fctEmC8ajY7I9H474RGxhag9606 rogid:+Ute8Lq5hnN0sLAQNWZb0cAbcTI9606 rigid:aTpm6yPvAhExkKldOVDQtslZrg8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NZC9 uniprotkb:P62987 intact:EBI-5457961|uniprotkb:A6NEH0|uniprotkb:Q53R00|uniprotkb:Q96AY1|uniprotkb:Q9NXQ5|uniprotkb:Q9UFH3|uniprotkb:Q9UI93|ensembl:ENSP00000349823|ensembl:ENSP00000350940 intact:EBI-357304|ensembl:ENSP00000388107|ensembl:ENSP00000396910|ensembl:ENSP00000470419|ensembl:ENSP00000470507|ensembl:ENSP00000471062|ensembl:ENSP00000471464|ensembl:ENSP00000471622|ensembl:ENSP00000472264|ensembl:ENSP00000472545|ensembl:ENSP00000473048|uniprotkb:P14793|uniprotkb:Q9BX98|uniprotkb:Q9UPK7|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:P62988|uniprotkb:Q29120|uniprotkb:Q6LBL4|uniprotkb:Q6LDU5|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9BWD6|uniprotkb:Q9UEF2|uniprotkb:Q9UEG1|uniprotkb:Q9UEK8 psi-mi:smal1_human(display_long)|uniprotkb:SMARCAL1(gene name)|psi-mi:SMARCAL1(display_short)|uniprotkb:HARP(gene name synonym)|uniprotkb:HepA-related protein(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 1(gene name synonym) psi-mi:rl40_human(display_long)|uniprotkb:UBA52(gene name)|psi-mi:UBA52(display_short)|uniprotkb:UBCEP2(gene name synonym)|uniprotkb:CEP52(gene name synonym)|uniprotkb:Ubiquitin A-52 residue ribosomal protein fusion product 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484762|imex:IM-26985-207 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120679.1|refseq:NP_054859.2|refseq:XP_005246688.1|refseq:XP_005246689.1|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031297"(replication fork processing)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|go:"GO:0070615"|ensembl:ENSG00000138375(gene)|ensembl:ENST00000357276(transcript)|ensembl:ENST00000358207(transcript)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR010003(HepA-related)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR030101|interpro:IPR038718|mint:Q9NZC9|rcsb pdb:4MQV|go:"GO:0090656"(t-circle formation) ensembl:ENSG00000221983(gene)|ensembl:ENST00000430157(transcript)|ensembl:ENST00000442744(transcript)|ensembl:ENST00000595158(transcript)|rcsb pdb:2MBH|rcsb pdb:2MJB|rcsb pdb:2MUR|ensembl:ENST00000595683(transcript)|ensembl:ENST00000596273(transcript)|rcsb pdb:2N3U|rcsb pdb:2N3V|rcsb pdb:2N3W|rcsb pdb:2NBD|ensembl:ENST00000596304(transcript)|rcsb pdb:2NBE|rcsb pdb:2RSU|rcsb pdb:4HJK|ensembl:ENST00000597451(transcript)|ensembl:ENST00000598780(transcript)|rcsb pdb:4JIO|rcsb pdb:4P4H|rcsb pdb:4PIG|ensembl:ENST00000599551(transcript)|ensembl:ENST00000599595(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|rcsb pdb:4PIH|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017085"(response to insecticide)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000626(Ubiquitin)|interpro:IPR001975(Ribosomal protein L40e)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR038587|mint:P62987|rcsb pdb:2LJ5|rcsb pdb:4PIJ|rcsb pdb:4RF0|rcsb pdb:4S1Z|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:4XKL|rcsb pdb:5AJ0|rcsb pdb:5GO7|rcsb pdb:5GO8|rcsb pdb:5GOB|rcsb pdb:5GOC|rcsb pdb:5GOD|rcsb pdb:5GOG|rcsb pdb:5GOH|rcsb pdb:5GOI|rcsb pdb:5GOJ|rcsb pdb:5GOK|rcsb pdb:5HPK|rcsb pdb:5HPL|rcsb pdb:5HPS|rcsb pdb:5HPT|rcsb pdb:5J26|rcsb pdb:5J8P|rcsb pdb:5JBV|rcsb pdb:5JBY|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:4RF1|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7AY1|rcsb pdb:7BHP|rcsb pdb:7M3Q|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|rcsb pdb:6Z6N|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|reactome:R-HSA-1253288|reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-162588|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-1799339|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|reactome:R-HSA-192823|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-211733|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2173788|reactome:R-HSA-2173791|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2408557|reactome:R-HSA-2467813|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-168928|reactome:R-HSA-174048|reactome:R-HSA-349425|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6791226|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8863795|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-69231|reactome:R-HSA-8951664|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9633012|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9683683|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-975163|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-977225|reactome:R-HSA-983168|refseq:NP_001029102.1|refseq:NP_003324.1|refseq:NP_001307947.1|refseq:NP_001307948.1|refseq:NP_001307949.1|refseq:NP_001307946.1 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:sUz7fctEmC8ajY7I9H474RGxhag9606 rogid:x9O/Pbww4D28M1+hIj+p0xrUXgU9606 rigid:aTpm6yPvAhExkKldOVDQtslZrg8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NZC9 uniprotkb:P53621 intact:EBI-5457961|uniprotkb:A6NEH0|uniprotkb:Q53R00|uniprotkb:Q96AY1|uniprotkb:Q9NXQ5|uniprotkb:Q9UFH3|uniprotkb:Q9UI93|ensembl:ENSP00000349823|ensembl:ENSP00000350940 intact:EBI-356273|intact:EBI-1188425|uniprotkb:Q5T201|uniprotkb:Q8IXZ9|intact:EBI-2559704|intact:EBI-11576606|ensembl:ENSP00000241704 psi-mi:smal1_human(display_long)|uniprotkb:SMARCAL1(gene name)|psi-mi:SMARCAL1(display_short)|uniprotkb:HARP(gene name synonym)|uniprotkb:HepA-related protein(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 1(gene name synonym) psi-mi:copa_human(display_long)|uniprotkb:COPA(gene name)|psi-mi:COPA(display_short)|uniprotkb:Alpha-coat protein(gene name synonym)|uniprotkb:HEP-COP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484762|imex:IM-26985-207 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120679.1|refseq:NP_054859.2|refseq:XP_005246688.1|refseq:XP_005246689.1|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031297"(replication fork processing)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|go:"GO:0070615"|ensembl:ENSG00000138375(gene)|ensembl:ENST00000357276(transcript)|ensembl:ENST00000358207(transcript)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR010003(HepA-related)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR030101|interpro:IPR038718|mint:Q9NZC9|rcsb pdb:4MQV|go:"GO:0090656"(t-circle formation) refseq:NP_001091868.1|refseq:NP_004362.2|ensembl:ENSG00000122218(gene)|ensembl:ENST00000241704(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005179"(hormone activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0016020"(membrane)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030157"(pancreatic juice secretion)|go:"GO:0030426"(growth cone)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR006692(Coatomer, WD associated region)|interpro:IPR010714(Coatomer, alpha subunit, C-terminal)|interpro:IPR011048(Cytochrome cd1-nitrite reductase-like, C-terminal haem d1)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR016391(Coatomer, alpha subunit)|interpro:IPR019775|interpro:IPR020472|interpro:IPR024977|interpro:IPR036322|mint:P53621|rcsb pdb:6PBG|rcsb pdb:6TZT|rcsb pdb:6U3V|reactome:R-HSA-6807878|reactome:R-HSA-6811434 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:sUz7fctEmC8ajY7I9H474RGxhag9606 rogid:9uP/NS7FjPrGDna1wcNHQy9py6A9606 rigid:aTpm6yPvAhExkKldOVDQtslZrg8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NZC9 uniprotkb:O14579 intact:EBI-5457961|uniprotkb:A6NEH0|uniprotkb:Q53R00|uniprotkb:Q96AY1|uniprotkb:Q9NXQ5|uniprotkb:Q9UFH3|uniprotkb:Q9UI93|ensembl:ENSP00000349823|ensembl:ENSP00000350940 intact:EBI-711301|uniprotkb:O76097|ensembl:ENSP00000262812|uniprotkb:Q9UGP6|uniprotkb:Q6IBB8|uniprotkb:A6NKA3|uniprotkb:A6NE29 psi-mi:smal1_human(display_long)|uniprotkb:SMARCAL1(gene name)|psi-mi:SMARCAL1(display_short)|uniprotkb:HARP(gene name synonym)|uniprotkb:HepA-related protein(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 1(gene name synonym) psi-mi:cope_human(display_long)|uniprotkb:COPE(gene name)|psi-mi:COPE(display_short)|uniprotkb:Epsilon-coat protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484762|imex:IM-26985-207 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120679.1|refseq:NP_054859.2|refseq:XP_005246688.1|refseq:XP_005246689.1|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031297"(replication fork processing)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|go:"GO:0070615"|ensembl:ENSG00000138375(gene)|ensembl:ENST00000357276(transcript)|ensembl:ENST00000358207(transcript)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR010003(HepA-related)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR030101|interpro:IPR038718|mint:Q9NZC9|rcsb pdb:4MQV|go:"GO:0090656"(t-circle formation) refseq:NP_009194.2|ensembl:ENSG00000105669(gene)|ensembl:ENST00000262812(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0015031"(protein transport)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0099612"(protein localization to axon)|interpro:IPR006822(Coatomer, epsilon subunit)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:O14579|rcsb pdb:6TZT|rcsb pdb:6U3V|reactome:R-HSA-6807878|reactome:R-HSA-6811434|refseq:NP_955474.1|refseq:NP_955476.1 - - comment:"author score: 27" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:sUz7fctEmC8ajY7I9H474RGxhag9606 rogid:gjrR0x7iNHl/nEDtoZTjThB1dgs9606 rigid:aTpm6yPvAhExkKldOVDQtslZrg8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NZC9 uniprotkb:Q15334 intact:EBI-5457961|uniprotkb:A6NEH0|uniprotkb:Q53R00|uniprotkb:Q96AY1|uniprotkb:Q9NXQ5|uniprotkb:Q9UFH3|uniprotkb:Q9UI93|ensembl:ENSP00000349823|ensembl:ENSP00000350940 intact:EBI-299979|ensembl:ENSP00000321537|ensembl:ENSP00000492144|uniprotkb:O00188|uniprotkb:Q58F11|uniprotkb:Q86UK6|uniprotkb:A7MBM7 psi-mi:smal1_human(display_long)|uniprotkb:SMARCAL1(gene name)|psi-mi:SMARCAL1(display_short)|uniprotkb:HARP(gene name synonym)|uniprotkb:HepA-related protein(gene name synonym)|uniprotkb:Sucrose nonfermenting protein 2-like 1(gene name synonym) psi-mi:l2gl1_human(display_long)|uniprotkb:DLG4(gene name synonym)|uniprotkb:LLGL1(gene name)|psi-mi:LLGL1(display_short)|uniprotkb:Human homolog to the D-lgl gene protein(gene name synonym)|uniprotkb:Hugl-1(gene name synonym)|uniprotkb:HUGL(gene name synonym)|uniprotkb:HUGL1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484762|imex:IM-26985-207 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001120679.1|refseq:NP_054859.2|refseq:XP_005246688.1|refseq:XP_005246689.1|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031297"(replication fork processing)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0043596"(nuclear replication fork)|go:"GO:0048478"(replication fork protection)|go:"GO:0070615"|ensembl:ENSG00000138375(gene)|ensembl:ENST00000357276(transcript)|ensembl:ENST00000358207(transcript)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR010003(HepA-related)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR030101|interpro:IPR038718|mint:Q9NZC9|rcsb pdb:4MQV|go:"GO:0090656"(t-circle formation) ensembl:ENSG00000131899(gene)|ensembl:ENSG00000284137(gene)|ensembl:ENST00000316843(transcript)|ensembl:ENST00000640494(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007409"(axonogenesis)|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032878"(regulation of establishment or maintenance of cell polarity)|go:"GO:0045159"(myosin II binding)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000664("Lethal(2) giant larvae protein")|interpro:IPR001680(WD40 repeat)|interpro:IPR013577(Lethal giant larvae homologue 2)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|go:"GO:0000137"(Golgi cis cisterna)|mint:Q15334|refseq:NP_004131.3 - - comment:"author score: 84" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:sUz7fctEmC8ajY7I9H474RGxhag9606 rogid:VqlrgKVnWmXyx1lvnpRe9hRQD0Q9606 rigid:aTpm6yPvAhExkKldOVDQtslZrg8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UBQ7 uniprotkb:Q14493 intact:EBI-372445|uniprotkb:Q9H3E9|uniprotkb:Q9UKX1|ensembl:ENSP00000313432|uniprotkb:Q5T945|uniprotkb:Q9H636 intact:EBI-2696402|uniprotkb:B3KRJ5|ensembl:ENSP00000417686 psi-mi:grhpr_human(display_long)|uniprotkb:MSTP035(orf name)|uniprotkb:GRHPR(gene name)|psi-mi:GRHPR(display_short)|uniprotkb:GLXR(gene name synonym) psi-mi:slbp_human(display_long)|uniprotkb:SLBP(gene name)|psi-mi:SLBP(display_short)|uniprotkb:HBP(gene name synonym)|uniprotkb:Histone stem-loop-binding protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25484753|imex:IM-26985-509 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_036335.1|go:"GO:0043648"(dicarboxylic acid metabolic process)|go:"GO:0046487"(glyoxylate metabolic process)|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070402"(NADPH binding)|go:"GO:1902494"(catalytic complex)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029753|interpro:IPR036291|mint:Q9UBQ7|rcsb pdb:2GCG|rcsb pdb:2H1S|rcsb pdb:2Q50|rcsb pdb:2WWR|reactome:R-HSA-389661|ensembl:ENSG00000137106(gene)|ensembl:ENST00000318158(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0007588"(excretion)|go:"GO:0008465"(glycerate dehydrogenase activity)|go:"GO:0016618"(hydroxypyruvate reductase activity)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0030267"("glyoxylate reductase (NADP+) activity")|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0042803"(protein homodimerization activity) refseq:NP_001293003.1|refseq:NP_001293004.1|refseq:NP_006518.1|ensembl:ENSG00000163950(gene)|ensembl:ENST00000489418(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006398"(mRNA 3'-end processing by stem-loop binding and cleavage)|go:"GO:0042802"(identical protein binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0071207"(histone pre-mRNA stem-loop binding)|go:"GO:0071208"(histone pre-mRNA DCP binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR026502|interpro:IPR029344|interpro:IPR038294|mint:Q14493|rcsb pdb:2KJM|rcsb pdb:4L8R|rcsb pdb:4QOZ|reactome:R-HSA-159230|reactome:R-HSA-73856|reactome:R-HSA-77588|dip:DIP-57045N - comment:"author score: 13" - figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qPHrh5I5wHI5MWba4zncz26cUnQ9606 rogid:Rt3HJRsfQ5SAgjMsloMR6H7Emho9606 rigid:8qGZhnUhk1hoYxvOkDOX0sZpgK4 false - tandem tag:n-n - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P22102 uniprotkb:Q8IXJ6 intact:EBI-356297|ensembl:ENSP00000371236|ensembl:ENSP00000371253|ensembl:ENSP00000371261|ensembl:ENSP00000459391|ensembl:ENSP00000459532|ensembl:ENSP00000461700|uniprotkb:D3DSF3|uniprotkb:D3DSF4|uniprotkb:O14659|uniprotkb:A8KA32|uniprotkb:A8K945|uniprotkb:Q52M77 intact:EBI-477232|uniprotkb:O95889|uniprotkb:Q924Y7|uniprotkb:Q9P0G8|uniprotkb:Q9UNT0|uniprotkb:Q9Y6E9|ensembl:ENSP00000249396|ensembl:ENSP00000489602|uniprotkb:A8K3V1|uniprotkb:B2RB45|uniprotkb:U5TP13 psi-mi:pur2_human(display_long)|uniprotkb:GART(gene name)|psi-mi:GART(display_short)|uniprotkb:PRGS(gene name synonym)|uniprotkb:PGFT(gene name synonym) psi-mi:sir2_human(display_long)|uniprotkb:SIR2-like protein 2(gene name synonym)|uniprotkb:SIRT2(gene name)|psi-mi:SIRT2(display_short)|uniprotkb:SIR2L(gene name synonym)|uniprotkb:SIR2L2(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25484744|imex:IM-26985-437 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0006544"(glycine metabolic process)|go:"GO:0009168"(purine ribonucleoside monophosphate biosynthetic process)|go:"GO:0010033"(response to organic substance)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0021549"(cerebellum development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0046084"(adenine biosynthetic process)|go:"GO:0046654"(tetrahydrofolate biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000115(Phosphoribosylglycinamide synthetase)|interpro:IPR001555(Phosphoribosylglycinamide formyltransferase, active site)|interpro:IPR002376(Formyl transferase, N-terminal)|interpro:IPR004607(Phosphoribosylglycinamide formyltransferase)|interpro:IPR004733(Phosphoribosylformylglycinamidine cyclo-ligase)|interpro:IPR010918(AIR synthase related protein, C-terminal)|ensembl:ENST00000571089(transcript)|interpro:IPR011054(Rudiment single hybrid motif)|interpro:IPR011761(ATP-grasp fold)|ensembl:ENST00000573055(transcript)|ensembl:ENST00000575273(transcript)|go:"GO:0003360"(brainstem development)|go:"GO:0004637"(phosphoribosylamine-glycine ligase activity)|go:"GO:0004641"(phosphoribosylformylglycinamidine cyclo-ligase activity)|interpro:IPR013815(ATP-grasp fold, subdomain 1)|go:"GO:0004644"(phosphoribosylglycinamide formyltransferase activity)|interpro:IPR016185(PreATP-grasp-like fold)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|interpro:IPR016188(PurM, N-terminal-like)|ensembl:ENSG00000159131(gene)|ensembl:ENSG00000262473(gene)|ensembl:ENST00000381815(transcript)|ensembl:ENST00000381831(transcript)|ensembl:ENST00000381839(transcript)|interpro:IPR020560|interpro:IPR020561|interpro:IPR020562|interpro:IPR036477|interpro:IPR036676|interpro:IPR036921|interpro:IPR037123|mint:P22102|rcsb pdb:1MEJ|rcsb pdb:1MEN|rcsb pdb:1MEO|rcsb pdb:1NJS|rcsb pdb:1RBM|rcsb pdb:1RBQ|rcsb pdb:1RBY|rcsb pdb:1RBZ|rcsb pdb:1RC0|rcsb pdb:1RC1|rcsb pdb:1ZLX|rcsb pdb:1ZLY|rcsb pdb:2QK4|rcsb pdb:2V9Y|rcsb pdb:4EW1|rcsb pdb:4EW2|rcsb pdb:4EW3|rcsb pdb:4ZYT|interpro:IPR020559|rcsb pdb:4ZYU|rcsb pdb:4ZYV|rcsb pdb:4ZYW|rcsb pdb:4ZYX|rcsb pdb:4ZYY|rcsb pdb:4ZYZ|rcsb pdb:4ZZ0|rcsb pdb:4ZZ1|rcsb pdb:4ZZ2|rcsb pdb:5J9F|rcsb pdb:7JG0|rcsb pdb:4ZZ3|refseq:NP_000810.1|refseq:NP_001129477.1|refseq:NP_001129478.1|refseq:NP_780294.1|rcsb pdb:7JG4|reactome:R-HSA-73817|rcsb pdb:7JG3|refseq:XP_011527828.1|refseq:XP_006724052.1|refseq:XP_006724053.1|refseq:XP_005260998.1 ensembl:ENSG00000068903(gene)|ensembl:ENSG00000283100(gene)|ensembl:ENST00000249396(transcript)|ensembl:ENST00000634533(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003950"(NAD+ ADP-ribosyltransferase activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006342"|go:"GO:0006348"|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006914"(autophagy)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0008134"(transcription factor binding)|rcsb pdb:6L66|rcsb pdb:6L71|rcsb pdb:6L72|rcsb pdb:6NR0|rcsb pdb:6QCN|rcsb pdb:7BOS|rcsb pdb:7BOT|reactome:R-HSA-2995383|rcsb pdb:5D7O|rcsb pdb:5D7P|rcsb pdb:5D7Q|rcsb pdb:5DY4|rcsb pdb:5DY5|rcsb pdb:5FYQ|rcsb pdb:5G4C|rcsb pdb:5MAR|rcsb pdb:5MAT|rcsb pdb:5Y0Z|rcsb pdb:5Y5N|rcsb pdb:5YQL|rcsb pdb:5YQM|rcsb pdb:5YQN|rcsb pdb:5YQO|rcsb pdb:6L65|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016575"(histone deacetylation)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0021762"(substantia nigra development)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0033010"(paranodal junction)|go:"GO:0033270"(paranode region of axon)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034979"(NAD-dependent protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035729"(cellular response to hepatocyte growth factor stimulus)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042325"(regulation of phosphorylation)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042903"(tubulin deacetylase activity)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043209"(myelin sheath)|go:"GO:0043219"(lateral loop)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0044242"(cellular lipid catabolic process)|go:"GO:0045087"(innate immune response)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045836"(positive regulation of meiotic nuclear division)|go:"GO:0045843"(negative regulation of striated muscle tissue development)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046970"("NAD-dependent histone deacetylase activity (H4-K16 specific)")|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051775"(response to redox state)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0051987"(positive regulation of attachment of spindle microtubules to kinetochore)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061433"(cellular response to caloric restriction)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070446"(negative regulation of oligodendrocyte progenitor proliferation)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0070933"(histone H4 deacetylation)|go:"GO:0071219"(cellular response to molecule of bacterial origin)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0072686"(mitotic spindle)|go:"GO:0072687"(meiotic spindle)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0097386"(glial cell projection)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1900195"(positive regulation of oocyte maturation)|go:"GO:1900425"(negative regulation of defense response to bacterium)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000777"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR017328(NAD-dependent deacetylase sirtuin-2, eukaryota)|interpro:IPR026590|interpro:IPR026591|interpro:IPR029035|mint:Q8IXJ6|rcsb pdb:1J8F|rcsb pdb:3ZGO|rcsb pdb:3ZGV|rcsb pdb:4L3O|rcsb pdb:4R8M|rcsb pdb:4RMG|rcsb pdb:4RMH|rcsb pdb:4RMI|rcsb pdb:4RMJ|rcsb pdb:4X3O|rcsb pdb:4X3P|rcsb pdb:4Y6L|rcsb pdb:4Y6O|go:"GO:0051301"(cell division)|rcsb pdb:4Y6Q|refseq:NP_001180215.1|refseq:NP_036369.2|refseq:NP_085096.1|refseq:XP_011524956.1|refseq:XP_011524957.1|refseq:XP_006723174.1|dip:DIP-33350N - comment:"author score: 18" - figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:7Iy33CtBsB8LHZFDP5mZ3eRX8pU9606 rogid:d4mOZOyT5RubJjE+a8wQhsWR6WI9606 rigid:6Bebs7EGLladCDA5kSzKmLHWfLg false - tandem tag:n-n - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92922 uniprotkb:Q8NFD5 intact:EBI-355653|uniprotkb:Q6P172|uniprotkb:Q8IWH2|uniprotkb:Q17RS0|ensembl:ENSP00000254480 intact:EBI-679921|uniprotkb:Q5JRD1|uniprotkb:Q5VYC4|uniprotkb:Q8IZY8|uniprotkb:Q8TEV0|uniprotkb:Q8TF02|uniprotkb:Q99491|uniprotkb:Q9ULI5|intact:EBI-2560572|ensembl:ENSP00000055163 psi-mi:smrc1_human(display_long)|uniprotkb:SMARCC1(gene name)|psi-mi:SMARCC1(display_short)|uniprotkb:BAF155(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1(gene name synonym)|uniprotkb:SWI/SNF complex 155 kDa subunit(gene name synonym)|uniprotkb:BRG1-associated factor 155(gene name synonym) psi-mi:ari1b_human(display_long)|uniprotkb:BAF250B(gene name synonym)|uniprotkb:Osa homolog 2(gene name synonym)|uniprotkb:p250R(gene name synonym)|uniprotkb:BRG1-binding protein hELD/OSA1(gene name synonym)|uniprotkb:BRG1-associated factor 250b(gene name synonym)|uniprotkb:ARID1B(gene name)|psi-mi:ARID1B(display_short)|uniprotkb:DAN15(gene name synonym)|uniprotkb:KIAA1235(gene name synonym)|uniprotkb:OSA2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484858|imex:IM-26985-359 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003065.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR000953(Chromo domain)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR030087|interpro:IPR032448|interpro:IPR032450|interpro:IPR032451|interpro:IPR036388|interpro:IPR036420|mint:Q92922|rcsb pdb:2YUS|rcsb pdb:5GJK|rcsb pdb:6KZ7|rcsb pdb:6YXO|rcsb pdb:6YXP|reactome:R-HSA-3214858|reactome:R-HSA-8939243|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|ensembl:ENSG00000173473(gene)|ensembl:ENST00000254480(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001741"(XY body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030850"(prostate gland development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|ensembl:ENSP00000254480|dip:DIP-27545N|dip:DIP-33044N refseq:NP_001333742.1|refseq:NP_059989.2|refseq:NP_065783.3|ensembl:ENSG00000049618(gene)|ensembl:ENST00000350026(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0035060"(brahma complex)|go:"GO:0043044"|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048096"|go:"GO:0071565"(nBAF complex)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR021906|interpro:IPR033388|interpro:IPR036431|interpro:IPR038040|mint:Q8NFD5|rcsb pdb:2CXY|rcsb pdb:2EH9|reactome:R-HSA-3214858|reactome:R-HSA-8939243 - - comment:"author score: 74" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Uv0bjPkUICLtOXJcETUXDTLIQhY9606 rogid:BeWhuwPk5f6HN+yasFEJRpkbM6A9606 rigid:6HeUPObda3Nl6rWrbmjXktbQ/94 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92922 uniprotkb:O14497 intact:EBI-355653|uniprotkb:Q6P172|uniprotkb:Q8IWH2|uniprotkb:Q17RS0|ensembl:ENSP00000254480 intact:EBI-637887|intact:EBI-28988406|ensembl:ENSP00000320485|uniprotkb:D3DPL1|uniprotkb:Q53FK9|uniprotkb:Q5T0W1|uniprotkb:Q5T0W2|uniprotkb:Q5T0W3|uniprotkb:Q8NFD6|uniprotkb:Q96T89|uniprotkb:Q9BY33|uniprotkb:Q9HBJ5|uniprotkb:Q9UPZ1 psi-mi:smrc1_human(display_long)|uniprotkb:SMARCC1(gene name)|psi-mi:SMARCC1(display_short)|uniprotkb:BAF155(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1(gene name synonym)|uniprotkb:SWI/SNF complex 155 kDa subunit(gene name synonym)|uniprotkb:BRG1-associated factor 155(gene name synonym) psi-mi:ari1a_human(display_long)|uniprotkb:hELD(gene name synonym)|uniprotkb:SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1(gene name synonym)|uniprotkb:SWI/SNF complex protein p270(gene name synonym)|uniprotkb:B120(gene name synonym)|uniprotkb:SWI-like protein(gene name synonym)|uniprotkb:Osa homolog 1(gene name synonym)|uniprotkb:BRG1-associated factor 250(gene name synonym)|uniprotkb:BRG1-associated factor 250a(gene name synonym)|uniprotkb:ARID1A(gene name)|psi-mi:ARID1A(display_short)|uniprotkb:C1orf4(gene name synonym)|uniprotkb:SMARCF1(gene name synonym)|uniprotkb:OSA1(gene name synonym)|uniprotkb:BAF250(gene name synonym)|uniprotkb:BAF250A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484858|imex:IM-26985-359 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003065.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR000953(Chromo domain)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR030087|interpro:IPR032448|interpro:IPR032450|interpro:IPR032451|interpro:IPR036388|interpro:IPR036420|mint:Q92922|rcsb pdb:2YUS|rcsb pdb:5GJK|rcsb pdb:6KZ7|rcsb pdb:6YXO|rcsb pdb:6YXP|reactome:R-HSA-3214858|reactome:R-HSA-8939243|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|ensembl:ENSG00000173473(gene)|ensembl:ENST00000254480(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001741"(XY body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030850"(prostate gland development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|ensembl:ENSP00000254480|dip:DIP-27545N|dip:DIP-33044N reactome:R-HSA-3214858|reactome:R-HSA-8939243|go:"GO:0005634"(nucleus)|ensembl:ENSG00000117713(gene)|go:"GO:0005654"(nucleoplasm)|ensembl:ENST00000324856(transcript)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0035060"(brahma complex)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043044"|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048096"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021906|interpro:IPR030094|interpro:IPR033388|interpro:IPR036431|mint:O14497|rcsb pdb:1RYU|rcsb pdb:6LTH|rcsb pdb:6LTJ|refseq:NP_006006.3|refseq:NP_624361.1|dip:DIP-33016N|ensembl:ENSP00000320485|ensembl:ENST00000374152|ensembl:ENSP00000363267|ensembl:ENST00000457599|ensembl:ENSP00000387636 - - comment:"author score: 122" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Uv0bjPkUICLtOXJcETUXDTLIQhY9606 rogid:C3ZRlsnBUZV6SBEbISRImamhzoQ9606 rigid:6HeUPObda3Nl6rWrbmjXktbQ/94 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92922 uniprotkb:O96019 intact:EBI-355653|uniprotkb:Q6P172|uniprotkb:Q8IWH2|uniprotkb:Q17RS0|ensembl:ENSP00000254480 intact:EBI-355018|uniprotkb:Q8TAE5|uniprotkb:Q9BVS8|uniprotkb:Q9H0W6|uniprotkb:B3KMN1|uniprotkb:D3DNR9|ensembl:ENSP00000397552 psi-mi:smrc1_human(display_long)|uniprotkb:SMARCC1(gene name)|psi-mi:SMARCC1(display_short)|uniprotkb:BAF155(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1(gene name synonym)|uniprotkb:SWI/SNF complex 155 kDa subunit(gene name synonym)|uniprotkb:BRG1-associated factor 155(gene name synonym) psi-mi:acl6a_human(display_long)|uniprotkb:53 kDa BRG1-associated factor A(gene name synonym)|uniprotkb:Actin-related protein Baf53a(gene name synonym)|uniprotkb:ArpNbeta(gene name synonym)|uniprotkb:BAF53A(gene name synonym)|uniprotkb:ACTL6A(gene name)|psi-mi:ACTL6A(display_short)|uniprotkb:BAF53(gene name synonym)|uniprotkb:INO80K(gene name synonym)|uniprotkb:INO80 complex subunit K(gene name synonym)|uniprotkb:BRG1-associated factor 53A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484858|imex:IM-26985-359 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003065.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR000953(Chromo domain)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR030087|interpro:IPR032448|interpro:IPR032450|interpro:IPR032451|interpro:IPR036388|interpro:IPR036420|mint:Q92922|rcsb pdb:2YUS|rcsb pdb:5GJK|rcsb pdb:6KZ7|rcsb pdb:6YXO|rcsb pdb:6YXP|reactome:R-HSA-3214858|reactome:R-HSA-8939243|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|ensembl:ENSG00000173473(gene)|ensembl:ENST00000254480(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001741"(XY body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030850"(prostate gland development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|ensembl:ENSP00000254480|dip:DIP-27545N|dip:DIP-33044N refseq:NP_004292.1|refseq:NP_817126.1|refseq:NP_829888.1|ensembl:ENSG00000136518(gene)|ensembl:ENST00000429709(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0003407"(neural retina development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0021510"(spinal cord development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043044"|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0071564"(npBAF complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR043129|mint:O96019|rcsb pdb:6LTJ|reactome:R-HSA-3214847|reactome:R-HSA-3214858|go:"GO:0000785"(chromatin)|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8939243|ensembl:ENST00000392662|ensembl:ENSP00000376430|ensembl:ENSP00000397552|ensembl:ENST00000450518|ensembl:ENSP00000394014|dip:DIP-27565N - - comment:"author score: 93" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Uv0bjPkUICLtOXJcETUXDTLIQhY9606 rogid:FV8zvQxf2aeHbwFNUpo9JOpj5U49606 rigid:6HeUPObda3Nl6rWrbmjXktbQ/94 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92922 uniprotkb:P51532 intact:EBI-355653|uniprotkb:Q6P172|uniprotkb:Q8IWH2|uniprotkb:Q17RS0|ensembl:ENSP00000254480 intact:EBI-302489|uniprotkb:O95052|uniprotkb:Q9HBD3|uniprotkb:B1A8Z4|uniprotkb:B1A8Z5|uniprotkb:B1A8Z6|uniprotkb:B1A8Z7|uniprotkb:E9PBR8|ensembl:ENSP00000343896|ensembl:ENSP00000395654 psi-mi:smrc1_human(display_long)|uniprotkb:SMARCC1(gene name)|psi-mi:SMARCC1(display_short)|uniprotkb:BAF155(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1(gene name synonym)|uniprotkb:SWI/SNF complex 155 kDa subunit(gene name synonym)|uniprotkb:BRG1-associated factor 155(gene name synonym) psi-mi:smca4_human(display_long)|uniprotkb:SMARCA4(gene name)|psi-mi:SMARCA4(display_short)|uniprotkb:BRG1(gene name synonym)|uniprotkb:SNF2B(gene name synonym)|uniprotkb:SNF2L4(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA4(gene name synonym)|uniprotkb:SNF2-beta(gene name synonym)|uniprotkb:BAF190A(gene name synonym)|uniprotkb:Mitotic growth and transcription activator(gene name synonym)|uniprotkb:Protein BRG-1(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4(gene name synonym)|uniprotkb:Protein brahma homolog 1(gene name synonym)|uniprotkb:BRG1-associated factor 190A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484858|imex:IM-26985-359 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003065.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR000953(Chromo domain)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR030087|interpro:IPR032448|interpro:IPR032450|interpro:IPR032451|interpro:IPR036388|interpro:IPR036420|mint:Q92922|rcsb pdb:2YUS|rcsb pdb:5GJK|rcsb pdb:6KZ7|rcsb pdb:6YXO|rcsb pdb:6YXP|reactome:R-HSA-3214858|reactome:R-HSA-8939243|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|ensembl:ENSG00000173473(gene)|ensembl:ENST00000254480(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001741"(XY body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030850"(prostate gland development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|ensembl:ENSP00000254480|dip:DIP-27545N|dip:DIP-33044N refseq:NP_001122316.1|refseq:NP_003063.2|refseq:NP_001122317.1|refseq:NP_001122318.1|refseq:NP_001122319.1|refseq:NP_001122320.1|dip:DIP-24249N|refseq:XP_016882654.1|refseq:XP_016882655.1|refseq:XP_016882656.1|refseq:XP_016882657.1|ensembl:ENSG00000127616(gene)|ensembl:ENST00000344626(transcript)|ensembl:ENST00000429416(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0002039"(p53 binding)|go:"GO:0003407"(neural retina development)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030100|interpro:IPR036427|interpro:IPR037259|interpro:IPR038718|mint:P51532|rcsb pdb:2GRC|rcsb pdb:2H60|rcsb pdb:3UVD|rcsb pdb:5DKD|rcsb pdb:5EA1|rcsb pdb:6BGH|rcsb pdb:6HR2|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6SY2|rcsb pdb:6ZS2|reactome:R-HSA-1266695|reactome:R-HSA-201722|reactome:R-HSA-3214858|reactome:R-HSA-3247509|reactome:R-HSA-8939243|reactome:R-HSA-9619665 - - comment:"author score: 115" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Uv0bjPkUICLtOXJcETUXDTLIQhY9606 rogid:Ztr+2IXfAxueSUaNYG2A47HoMes9606 rigid:6HeUPObda3Nl6rWrbmjXktbQ/94 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92922 uniprotkb:Q8TAQ2 intact:EBI-355653|uniprotkb:Q6P172|uniprotkb:Q8IWH2|uniprotkb:Q17RS0|ensembl:ENSP00000254480 intact:EBI-357418|ensembl:ENSP00000267064|uniprotkb:Q92923|uniprotkb:Q96E12|uniprotkb:Q96GY4|intact:EBI-1759986|intact:EBI-1965079|uniprotkb:F8VTJ5|uniprotkb:Q59GV3 psi-mi:smrc1_human(display_long)|uniprotkb:SMARCC1(gene name)|psi-mi:SMARCC1(display_short)|uniprotkb:BAF155(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1(gene name synonym)|uniprotkb:SWI/SNF complex 155 kDa subunit(gene name synonym)|uniprotkb:BRG1-associated factor 155(gene name synonym) psi-mi:smrc2_human(display_long)|uniprotkb:SMARCC2(gene name)|psi-mi:SMARCC2(display_short)|uniprotkb:BAF170(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2(gene name synonym)|uniprotkb:SWI/SNF complex 170 kDa subunit(gene name synonym)|uniprotkb:BRG1-associated factor 170(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484858|imex:IM-26985-359 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003065.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR000953(Chromo domain)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR030087|interpro:IPR032448|interpro:IPR032450|interpro:IPR032451|interpro:IPR036388|interpro:IPR036420|mint:Q92922|rcsb pdb:2YUS|rcsb pdb:5GJK|rcsb pdb:6KZ7|rcsb pdb:6YXO|rcsb pdb:6YXP|reactome:R-HSA-3214858|reactome:R-HSA-8939243|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|ensembl:ENSG00000173473(gene)|ensembl:ENST00000254480(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001741"(XY body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030850"(prostate gland development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|ensembl:ENSP00000254480|dip:DIP-27545N|dip:DIP-33044N ensembl:ENSG00000139613(gene)|ensembl:ENST00000267064(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR000953(Chromo domain)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR032448|interpro:IPR032450|interpro:IPR032451|interpro:IPR036388|interpro:IPR036420|interpro:IPR038044|mint:Q8TAQ2|rcsb pdb:6KAG|rcsb pdb:6LTH|rcsb pdb:6LTJ|reactome:R-HSA-3214858|reactome:R-HSA-8939243|refseq:NP_003066.2|refseq:NP_001123892.1|refseq:NP_620706.1|refseq:NP_001317217.1|dip:DIP-27611N - - comment:"author score: 138" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Uv0bjPkUICLtOXJcETUXDTLIQhY9606 rogid:60gIB3J1YI/FzqVCzdoSg1Oj3ME9606 rigid:6HeUPObda3Nl6rWrbmjXktbQ/94 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92922 uniprotkb:Q96GM5 intact:EBI-355653|uniprotkb:Q6P172|uniprotkb:Q8IWH2|uniprotkb:Q17RS0|ensembl:ENSP00000254480 intact:EBI-358489|intact:EBI-1760001|ensembl:ENSP00000378414|uniprotkb:Q92924|uniprotkb:Q9Y635|intact:EBI-1965109|uniprotkb:A6NN27|intact:EBI-28976725 psi-mi:smrc1_human(display_long)|uniprotkb:SMARCC1(gene name)|psi-mi:SMARCC1(display_short)|uniprotkb:BAF155(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1(gene name synonym)|uniprotkb:SWI/SNF complex 155 kDa subunit(gene name synonym)|uniprotkb:BRG1-associated factor 155(gene name synonym) psi-mi:smrd1_human(display_long)|uniprotkb:SMARCD1(gene name)|psi-mi:SMARCD1(display_short)|uniprotkb:BAF60A(gene name synonym)|uniprotkb:SWI/SNF complex 60 kDa subunit(gene name synonym)|uniprotkb:60 kDa BRG-1/Brm-associated factor subunit A(gene name synonym)|uniprotkb:BRG1-associated factor 60A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484858|imex:IM-26985-359 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003065.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR000953(Chromo domain)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR030087|interpro:IPR032448|interpro:IPR032450|interpro:IPR032451|interpro:IPR036388|interpro:IPR036420|mint:Q92922|rcsb pdb:2YUS|rcsb pdb:5GJK|rcsb pdb:6KZ7|rcsb pdb:6YXO|rcsb pdb:6YXP|reactome:R-HSA-3214858|reactome:R-HSA-8939243|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|ensembl:ENSG00000173473(gene)|ensembl:ENST00000254480(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001741"(XY body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030850"(prostate gland development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|ensembl:ENSP00000254480|dip:DIP-27545N|dip:DIP-33044N ensembl:ENSG00000066117(gene)|ensembl:ENST00000394963(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048096"|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071564"(npBAF complex)|refseq:NP_003067.3|refseq:NP_620710.2|ensembl:ENST00000381513|ensembl:ENSP00000370924|ensembl:ENSP00000378414|go:"GO:0071565"(nBAF complex)|interpro:IPR003121(SWIB/MDM2)|interpro:IPR019835|interpro:IPR036885|interpro:IPR038041|mint:Q96GM5|rcsb pdb:6LTH|rcsb pdb:6LTJ|reactome:R-HSA-3214858|reactome:R-HSA-8939243|dip:DIP-33390N - - comment:"author score: 146" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Uv0bjPkUICLtOXJcETUXDTLIQhY9606 rogid:cwqYnl+J8glG8YjW1ps77Dd105Y9606 rigid:6HeUPObda3Nl6rWrbmjXktbQ/94 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q92922 uniprotkb:Q92925 intact:EBI-355653|uniprotkb:Q6P172|uniprotkb:Q8IWH2|uniprotkb:Q17RS0|ensembl:ENSP00000254480 intact:EBI-358441|uniprotkb:Q7L2I6|uniprotkb:Q9UHZ1|uniprotkb:A5PLL5|uniprotkb:A6NNQ7|uniprotkb:B4DV56|uniprotkb:B4E1R6|ensembl:ENSP00000392617 psi-mi:smrc1_human(display_long)|uniprotkb:SMARCC1(gene name)|psi-mi:SMARCC1(display_short)|uniprotkb:BAF155(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1(gene name synonym)|uniprotkb:SWI/SNF complex 155 kDa subunit(gene name synonym)|uniprotkb:BRG1-associated factor 155(gene name synonym) psi-mi:smrd2_human(display_long)|uniprotkb:PRO2451(orf name)|uniprotkb:SMARCD2(gene name)|psi-mi:SMARCD2(display_short)|uniprotkb:BAF60B(gene name synonym)|uniprotkb:60 kDa BRG-1/Brm-associated factor subunit B(gene name synonym)|uniprotkb:BRG1-associated factor 60B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484858|imex:IM-26985-359 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003065.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR000953(Chromo domain)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR030087|interpro:IPR032448|interpro:IPR032450|interpro:IPR032451|interpro:IPR036388|interpro:IPR036420|mint:Q92922|rcsb pdb:2YUS|rcsb pdb:5GJK|rcsb pdb:6KZ7|rcsb pdb:6YXO|rcsb pdb:6YXP|reactome:R-HSA-3214858|reactome:R-HSA-8939243|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|ensembl:ENSG00000173473(gene)|ensembl:ENST00000254480(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001741"(XY body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030850"(prostate gland development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|ensembl:ENSP00000254480|dip:DIP-27545N|dip:DIP-33044N refseq:NP_001091896.1|dip:DIP-31182N|refseq:NP_001317369.1|ensembl:ENSG00000108604(gene)|ensembl:ENST00000448276(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR003121(SWIB/MDM2)|interpro:IPR019835|interpro:IPR030090|interpro:IPR036885|mint:Q92925|reactome:R-HSA-3214858|reactome:R-HSA-8939243 - - comment:"author score: 149" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Uv0bjPkUICLtOXJcETUXDTLIQhY9606 rogid:n6YHBJ+cqEmVcXwMYsTZGOfL86A9606 rigid:6HeUPObda3Nl6rWrbmjXktbQ/94 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q12824 uniprotkb:Q86U86 intact:EBI-358419|uniprotkb:O75784|uniprotkb:O95474|uniprotkb:Q38GA1|uniprotkb:Q76N08|uniprotkb:Q9UBH2|ensembl:ENSP00000479330|ensembl:ENSP00000494049|uniprotkb:Q17S11 intact:EBI-637807|uniprotkb:Q9H2T3|uniprotkb:Q9H2T4|uniprotkb:Q9H2T5|uniprotkb:Q9H301|uniprotkb:Q9H314|uniprotkb:A1L381|uniprotkb:A1L382|uniprotkb:A4FUJ7|uniprotkb:Q1RMD1|uniprotkb:Q1RMD2|uniprotkb:Q96MS2|ensembl:ENSP00000296302 psi-mi:snf5_human(display_long)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:INI1(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:BAF47(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym) psi-mi:pb1_human(display_long)|uniprotkb:Polybromo-1D(gene name synonym)|uniprotkb:BRG1-associated factor 180(gene name synonym)|uniprotkb:PBRM1(gene name)|psi-mi:PBRM1(display_short)|uniprotkb:PB1(gene name synonym)|uniprotkb:BAF180(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484786|imex:IM-26985-357 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q12824|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|rcsb pdb:5AJ1|rcsb pdb:5GJK|rcsb pdb:5L7A|rcsb pdb:5L7B|go:"GO:0007049"(cell cycle)|rcsb pdb:6AX5|go:"GO:0007399"(nervous system development)|rcsb pdb:6KAG|rcsb pdb:6KZ7|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6UCH|reactome:R-HSA-3214858|go:"GO:0008285"(negative regulation of cell population proliferation)|reactome:R-HSA-8939243|go:"GO:0015074"(DNA integration)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035060"(brahma complex)|go:"GO:0039692"(single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1900110"(negative regulation of histone H3-K9 dimethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR006939(SNF5/SMARCB1/INI1)|interpro:IPR017393(SWI/SNF chromatin-remodeling complex, component hSNF5/Ini1)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|refseq:NP_001007469.1|refseq:NP_003064.2|ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|ensembl:ENST00000618915(transcript)|ensembl:ENST00000644036(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0001741"(XY body)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-27550N refseq:NP_060783.3|ensembl:ENSG00000163939(gene)|ensembl:ENST00000296302(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016586"(RSC-type complex)|go:"GO:0043044"|interpro:IPR001025(Bromo adjacent region)|interpro:IPR001487(Bromodomain)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR018359|interpro:IPR036427|interpro:IPR036910|interpro:IPR037382|interpro:IPR037968|interpro:IPR043151|mint:Q86U86|rcsb pdb:2KTB|rcsb pdb:3G0J|rcsb pdb:3HMF|rcsb pdb:3IU5|rcsb pdb:3IU6|rcsb pdb:3K2J|rcsb pdb:3LJW|rcsb pdb:3MB4|rcsb pdb:3TLP|rcsb pdb:4Q0N|rcsb pdb:4Q0O|rcsb pdb:4Y03|rcsb pdb:5E7D|rcsb pdb:5FH6|rcsb pdb:5FH7|rcsb pdb:5FH8|rcsb pdb:5HRV|rcsb pdb:5HRW|rcsb pdb:5HRX|rcsb pdb:5II1|rcsb pdb:5II2|rcsb pdb:5IID|rcsb pdb:6OXB|rcsb pdb:6ZN6|rcsb pdb:6ZNV|rcsb pdb:6ZS3|rcsb pdb:6ZS4|reactome:R-HSA-3214858|reactome:R-HSA-8939243|dip:DIP-33045N|refseq:XP_016862237.1|refseq:XP_016862238.1|refseq:XP_016862239.1|refseq:XP_016862246.1|refseq:XP_016862247.1|refseq:NP_851385.1 - - comment:"author score: 57" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I9606 rogid:nJp9kwLE9qxj6DcyEO8dUok6k/Q9606 rigid:enWTmGjOUGt2tOv4q1fUv/rvjdU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q12824 uniprotkb:Q68CP9 intact:EBI-358419|uniprotkb:O75784|uniprotkb:O95474|uniprotkb:Q38GA1|uniprotkb:Q76N08|uniprotkb:Q9UBH2|ensembl:ENSP00000479330|ensembl:ENSP00000494049|uniprotkb:Q17S11 intact:EBI-637818|uniprotkb:Q15KG9|uniprotkb:Q5EB51|uniprotkb:Q645I3|uniprotkb:Q6ZRY5|uniprotkb:Q7Z3I5|uniprotkb:Q86T28|uniprotkb:Q96SJ6|uniprotkb:Q9HCL5|ensembl:ENSP00000335044 psi-mi:snf5_human(display_long)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:INI1(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:BAF47(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym) psi-mi:arid2_human(display_long)|uniprotkb:BRG1-associated factor 200(gene name synonym)|uniprotkb:Zinc finger protein with activation potential(gene name synonym)|uniprotkb:Zipzap/p200(gene name synonym)|uniprotkb:ARID2(gene name)|psi-mi:ARID2(display_short)|uniprotkb:KIAA1557(gene name synonym)|uniprotkb:BAF200(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484786|imex:IM-26985-357 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q12824|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|rcsb pdb:5AJ1|rcsb pdb:5GJK|rcsb pdb:5L7A|rcsb pdb:5L7B|go:"GO:0007049"(cell cycle)|rcsb pdb:6AX5|go:"GO:0007399"(nervous system development)|rcsb pdb:6KAG|rcsb pdb:6KZ7|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6UCH|reactome:R-HSA-3214858|go:"GO:0008285"(negative regulation of cell population proliferation)|reactome:R-HSA-8939243|go:"GO:0015074"(DNA integration)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035060"(brahma complex)|go:"GO:0039692"(single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1900110"(negative regulation of histone H3-K9 dimethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR006939(SNF5/SMARCB1/INI1)|interpro:IPR017393(SWI/SNF chromatin-remodeling complex, component hSNF5/Ini1)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|refseq:NP_001007469.1|refseq:NP_003064.2|ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|ensembl:ENST00000618915(transcript)|ensembl:ENST00000644036(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0001741"(XY body)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-27550N refseq:NP_689854.2|ensembl:ENSG00000189079(gene)|ensembl:ENST00000334344(transcript)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042592"(homeostatic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048568"(embryonic organ development)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003150(DNA-binding RFX)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR036388|interpro:IPR036390|interpro:IPR036431|mint:Q68CP9|reactome:R-HSA-3214858|reactome:R-HSA-8939243|dip:DIP-33391N|refseq:NP_001334768.1|ensembl:ENSP00000335044 - - comment:"author score: 58" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I9606 rogid:7AJ6PqICERVZS+s3sZBIBODzs/I9606 rigid:enWTmGjOUGt2tOv4q1fUv/rvjdU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q12824 uniprotkb:Q8NFD5 intact:EBI-358419|uniprotkb:O75784|uniprotkb:O95474|uniprotkb:Q38GA1|uniprotkb:Q76N08|uniprotkb:Q9UBH2|ensembl:ENSP00000479330|ensembl:ENSP00000494049|uniprotkb:Q17S11 intact:EBI-679921|uniprotkb:Q5JRD1|uniprotkb:Q5VYC4|uniprotkb:Q8IZY8|uniprotkb:Q8TEV0|uniprotkb:Q8TF02|uniprotkb:Q99491|uniprotkb:Q9ULI5|intact:EBI-2560572|ensembl:ENSP00000055163 psi-mi:snf5_human(display_long)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:INI1(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:BAF47(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym) psi-mi:ari1b_human(display_long)|uniprotkb:BAF250B(gene name synonym)|uniprotkb:Osa homolog 2(gene name synonym)|uniprotkb:p250R(gene name synonym)|uniprotkb:BRG1-binding protein hELD/OSA1(gene name synonym)|uniprotkb:BRG1-associated factor 250b(gene name synonym)|uniprotkb:ARID1B(gene name)|psi-mi:ARID1B(display_short)|uniprotkb:DAN15(gene name synonym)|uniprotkb:KIAA1235(gene name synonym)|uniprotkb:OSA2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484786|imex:IM-26985-357 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q12824|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|rcsb pdb:5AJ1|rcsb pdb:5GJK|rcsb pdb:5L7A|rcsb pdb:5L7B|go:"GO:0007049"(cell cycle)|rcsb pdb:6AX5|go:"GO:0007399"(nervous system development)|rcsb pdb:6KAG|rcsb pdb:6KZ7|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6UCH|reactome:R-HSA-3214858|go:"GO:0008285"(negative regulation of cell population proliferation)|reactome:R-HSA-8939243|go:"GO:0015074"(DNA integration)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035060"(brahma complex)|go:"GO:0039692"(single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1900110"(negative regulation of histone H3-K9 dimethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR006939(SNF5/SMARCB1/INI1)|interpro:IPR017393(SWI/SNF chromatin-remodeling complex, component hSNF5/Ini1)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|refseq:NP_001007469.1|refseq:NP_003064.2|ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|ensembl:ENST00000618915(transcript)|ensembl:ENST00000644036(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0001741"(XY body)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-27550N refseq:NP_001333742.1|refseq:NP_059989.2|refseq:NP_065783.3|ensembl:ENSG00000049618(gene)|ensembl:ENST00000350026(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0035060"(brahma complex)|go:"GO:0043044"|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048096"|go:"GO:0071565"(nBAF complex)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR021906|interpro:IPR033388|interpro:IPR036431|interpro:IPR038040|mint:Q8NFD5|rcsb pdb:2CXY|rcsb pdb:2EH9|reactome:R-HSA-3214858|reactome:R-HSA-8939243 - - comment:"author score: 105" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I9606 rogid:BeWhuwPk5f6HN+yasFEJRpkbM6A9606 rigid:enWTmGjOUGt2tOv4q1fUv/rvjdU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q12824 uniprotkb:P51531 intact:EBI-358419|uniprotkb:O75784|uniprotkb:O95474|uniprotkb:Q38GA1|uniprotkb:Q76N08|uniprotkb:Q9UBH2|ensembl:ENSP00000479330|ensembl:ENSP00000494049|uniprotkb:Q17S11 intact:EBI-679562|uniprotkb:B1ALG3|uniprotkb:B1ALG4|uniprotkb:D3DRH4|uniprotkb:D3DRH5|ensembl:ENSP00000265773|ensembl:ENSP00000371638 psi-mi:snf5_human(display_long)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:INI1(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:BAF47(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym) psi-mi:smca2_human(display_long)|uniprotkb:ATP-dependent helicase SMARCA2(gene name synonym)|uniprotkb:SNF2-alpha(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2(gene name synonym)|uniprotkb:SMARCA2(gene name)|psi-mi:SMARCA2(display_short)|uniprotkb:BRM(gene name synonym)|uniprotkb:SNF2A(gene name synonym)|uniprotkb:SNF2L2(gene name synonym)|uniprotkb:BAF190B(gene name synonym)|uniprotkb:Protein brahma homolog(gene name synonym)|uniprotkb:BRG1-associated factor 190B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484786|imex:IM-26985-357 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q12824|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|rcsb pdb:5AJ1|rcsb pdb:5GJK|rcsb pdb:5L7A|rcsb pdb:5L7B|go:"GO:0007049"(cell cycle)|rcsb pdb:6AX5|go:"GO:0007399"(nervous system development)|rcsb pdb:6KAG|rcsb pdb:6KZ7|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6UCH|reactome:R-HSA-3214858|go:"GO:0008285"(negative regulation of cell population proliferation)|reactome:R-HSA-8939243|go:"GO:0015074"(DNA integration)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035060"(brahma complex)|go:"GO:0039692"(single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1900110"(negative regulation of histone H3-K9 dimethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR006939(SNF5/SMARCB1/INI1)|interpro:IPR017393(SWI/SNF chromatin-remodeling complex, component hSNF5/Ini1)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|refseq:NP_001007469.1|refseq:NP_003064.2|ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|ensembl:ENST00000618915(transcript)|ensembl:ENST00000644036(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0001741"(XY body)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-27550N refseq:NP_003061.3|refseq:NP_620614.2|refseq:NP_001276325.1|refseq:NP_001276326.1|dip:DIP-29005N|ensembl:ENSG00000080503(gene)|ensembl:ENST00000349721(transcript)|ensembl:ENST00000382203(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007286"(spermatid development)|go:"GO:0007399"(nervous system development)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070615"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030088|interpro:IPR036427|interpro:IPR037259|interpro:IPR038718|mint:P51531|rcsb pdb:2DAT|rcsb pdb:4QY4|rcsb pdb:5DKC|rcsb pdb:5DKH|rcsb pdb:6EG2|rcsb pdb:6EG3|rcsb pdb:6HAX|rcsb pdb:6HAY|rcsb pdb:6HAZ|reactome:R-HSA-3214858|reactome:R-HSA-8939243 - - comment:"author score: 165" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I9606 rogid:DmQot4h4SmtqmUGBgF5ictTah289606 rigid:enWTmGjOUGt2tOv4q1fUv/rvjdU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q12824 uniprotkb:O14497 intact:EBI-358419|uniprotkb:O75784|uniprotkb:O95474|uniprotkb:Q38GA1|uniprotkb:Q76N08|uniprotkb:Q9UBH2|ensembl:ENSP00000479330|ensembl:ENSP00000494049|uniprotkb:Q17S11 intact:EBI-637887|intact:EBI-28988406|ensembl:ENSP00000320485|uniprotkb:D3DPL1|uniprotkb:Q53FK9|uniprotkb:Q5T0W1|uniprotkb:Q5T0W2|uniprotkb:Q5T0W3|uniprotkb:Q8NFD6|uniprotkb:Q96T89|uniprotkb:Q9BY33|uniprotkb:Q9HBJ5|uniprotkb:Q9UPZ1 psi-mi:snf5_human(display_long)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:INI1(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:BAF47(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym) psi-mi:ari1a_human(display_long)|uniprotkb:hELD(gene name synonym)|uniprotkb:SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1(gene name synonym)|uniprotkb:SWI/SNF complex protein p270(gene name synonym)|uniprotkb:B120(gene name synonym)|uniprotkb:SWI-like protein(gene name synonym)|uniprotkb:Osa homolog 1(gene name synonym)|uniprotkb:BRG1-associated factor 250(gene name synonym)|uniprotkb:BRG1-associated factor 250a(gene name synonym)|uniprotkb:ARID1A(gene name)|psi-mi:ARID1A(display_short)|uniprotkb:C1orf4(gene name synonym)|uniprotkb:SMARCF1(gene name synonym)|uniprotkb:OSA1(gene name synonym)|uniprotkb:BAF250(gene name synonym)|uniprotkb:BAF250A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484786|imex:IM-26985-357 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q12824|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|rcsb pdb:5AJ1|rcsb pdb:5GJK|rcsb pdb:5L7A|rcsb pdb:5L7B|go:"GO:0007049"(cell cycle)|rcsb pdb:6AX5|go:"GO:0007399"(nervous system development)|rcsb pdb:6KAG|rcsb pdb:6KZ7|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6UCH|reactome:R-HSA-3214858|go:"GO:0008285"(negative regulation of cell population proliferation)|reactome:R-HSA-8939243|go:"GO:0015074"(DNA integration)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035060"(brahma complex)|go:"GO:0039692"(single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1900110"(negative regulation of histone H3-K9 dimethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR006939(SNF5/SMARCB1/INI1)|interpro:IPR017393(SWI/SNF chromatin-remodeling complex, component hSNF5/Ini1)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|refseq:NP_001007469.1|refseq:NP_003064.2|ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|ensembl:ENST00000618915(transcript)|ensembl:ENST00000644036(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0001741"(XY body)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-27550N reactome:R-HSA-3214858|reactome:R-HSA-8939243|go:"GO:0005634"(nucleus)|ensembl:ENSG00000117713(gene)|go:"GO:0005654"(nucleoplasm)|ensembl:ENST00000324856(transcript)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0035060"(brahma complex)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043044"|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048096"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021906|interpro:IPR030094|interpro:IPR033388|interpro:IPR036431|mint:O14497|rcsb pdb:1RYU|rcsb pdb:6LTH|rcsb pdb:6LTJ|refseq:NP_006006.3|refseq:NP_624361.1|dip:DIP-33016N|ensembl:ENSP00000320485|ensembl:ENST00000374152|ensembl:ENSP00000363267|ensembl:ENST00000457599|ensembl:ENSP00000387636 - - comment:"author score: 171" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I9606 rogid:C3ZRlsnBUZV6SBEbISRImamhzoQ9606 rigid:enWTmGjOUGt2tOv4q1fUv/rvjdU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q12824 uniprotkb:Q8WUZ0 intact:EBI-358419|uniprotkb:O75784|uniprotkb:O95474|uniprotkb:Q38GA1|uniprotkb:Q76N08|uniprotkb:Q9UBH2|ensembl:ENSP00000479330|ensembl:ENSP00000494049|uniprotkb:Q17S11 intact:EBI-7850114|intact:EBI-28969068|ensembl:ENSP00000215115|uniprotkb:Q6PD89|uniprotkb:O43770|intact:MINT-4535839 psi-mi:snf5_human(display_long)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:INI1(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:BAF47(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym) psi-mi:bcl7c_human(display_long)|uniprotkb:BCL7C(gene name)|psi-mi:BCL7C(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484786|imex:IM-26985-357 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q12824|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|rcsb pdb:5AJ1|rcsb pdb:5GJK|rcsb pdb:5L7A|rcsb pdb:5L7B|go:"GO:0007049"(cell cycle)|rcsb pdb:6AX5|go:"GO:0007399"(nervous system development)|rcsb pdb:6KAG|rcsb pdb:6KZ7|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6UCH|reactome:R-HSA-3214858|go:"GO:0008285"(negative regulation of cell population proliferation)|reactome:R-HSA-8939243|go:"GO:0015074"(DNA integration)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035060"(brahma complex)|go:"GO:0039692"(single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1900110"(negative regulation of histone H3-K9 dimethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR006939(SNF5/SMARCB1/INI1)|interpro:IPR017393(SWI/SNF chromatin-remodeling complex, component hSNF5/Ini1)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|refseq:NP_001007469.1|refseq:NP_003064.2|ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|ensembl:ENST00000618915(transcript)|ensembl:ENST00000644036(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0001741"(XY body)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-27550N refseq:NP_001273455.1|ensembl:ENSP00000215115|ensembl:ENST00000380317|ensembl:ENSP00000369674|ensembl:ENSG00000099385(gene)|ensembl:ENST00000215115(transcript)|go:"GO:0006915"(apoptotic process)|interpro:IPR006804(BCL7, N-terminal)|mint:Q8WUZ0|refseq:NP_004756.2 - - comment:mint|comment:homomint|function:May play an anti-apoptotic role|comment:"author score: 169" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I9606 rogid:XuyDhxOhWHNVXmgi/WXLmCvKn409606 rigid:enWTmGjOUGt2tOv4q1fUv/rvjdU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q12824 uniprotkb:P04745 intact:EBI-358419|uniprotkb:O75784|uniprotkb:O95474|uniprotkb:Q38GA1|uniprotkb:Q76N08|uniprotkb:Q9UBH2|ensembl:ENSP00000479330|ensembl:ENSP00000494049|uniprotkb:Q17S11 intact:EBI-738586|uniprotkb:Q13763|uniprotkb:A6NJS5|uniprotkb:A8K8H6|uniprotkb:Q5T083 psi-mi:snf5_human(display_long)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:INI1(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:BAF47(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym) psi-mi:amy1a_human(display_long)|uniprotkb:AMY1A(gene name)|psi-mi:AMY1A(display_short)|uniprotkb:AMY1(gene name synonym)|uniprotkb:1,4-alpha-D-glucan glucanohydrolase 1(gene name synonym)|uniprotkb:Salivary alpha-amylase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484786|imex:IM-26985-357 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q12824|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|rcsb pdb:5AJ1|rcsb pdb:5GJK|rcsb pdb:5L7A|rcsb pdb:5L7B|go:"GO:0007049"(cell cycle)|rcsb pdb:6AX5|go:"GO:0007399"(nervous system development)|rcsb pdb:6KAG|rcsb pdb:6KZ7|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6UCH|reactome:R-HSA-3214858|go:"GO:0008285"(negative regulation of cell population proliferation)|reactome:R-HSA-8939243|go:"GO:0015074"(DNA integration)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035060"(brahma complex)|go:"GO:0039692"(single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1900110"(negative regulation of histone H3-K9 dimethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR006939(SNF5/SMARCB1/INI1)|interpro:IPR017393(SWI/SNF chromatin-remodeling complex, component hSNF5/Ini1)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|refseq:NP_001007469.1|refseq:NP_003064.2|ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|ensembl:ENST00000618915(transcript)|ensembl:ENST00000644036(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0001741"(XY body)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-27550N ensembl:ENST00000330330|ensembl:ENST00000370079|ensembl:ENST00000370080|ensembl:ENST00000370083|refseq:NP_001008219.1|refseq:NP_001008220.1|refseq:NP_001008222.1|refseq:NP_004029.2|interpro:IPR006048(Alpha-amylase, C-terminal all beta)|interpro:IPR006046(Glycoside hydrolase family 13)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|go:"GO:0004556"(alpha-amylase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0005975"(carbohydrate metabolic process)|rcsb pdb:1C8Q|rcsb pdb:1JXJ|rcsb pdb:1JXK|rcsb pdb:1MFU|rcsb pdb:1MFV|rcsb pdb:1NM9|rcsb pdb:1Q4N|rcsb pdb:1SMD|rcsb pdb:1XV8|rcsb pdb:1Z32|rcsb pdb:3BLK|rcsb pdb:3BLP|rcsb pdb:3DHP|refseq:XP_016856547.1|interpro:IPR031319|reactome:R-HSA-189085|go:"GO:0005615"(extracellular space)|go:"GO:0070062"(extracellular exosome)|refseq:XP_011539564.1|refseq:NP_001333709.1|ensembl:ENSG00000174876|ensembl:ENSG00000187733|ensembl:ENSG00000237763|ensembl:ENSP00000330484|ensembl:ENSP00000359096|ensembl:ENSP00000359097|ensembl:ENSP00000359100|go:"GO:0103025"|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta) - - caution:This sequence has been withdrawn from Uniprot.|comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I9606 rogid:Gwt64Wrt6IUZmCIxM3CXQxe7W509606 rigid:enWTmGjOUGt2tOv4q1fUv/rvjdU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q12824 uniprotkb:P68032 intact:EBI-358419|uniprotkb:O75784|uniprotkb:O95474|uniprotkb:Q38GA1|uniprotkb:Q76N08|uniprotkb:Q9UBH2|ensembl:ENSP00000479330|ensembl:ENSP00000494049|uniprotkb:Q17S11 intact:EBI-352273|uniprotkb:P04270|ensembl:ENSP00000290378 psi-mi:snf5_human(display_long)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:INI1(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:BAF47(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym) psi-mi:actc_human(display_long)|uniprotkb:ACTC1(gene name)|psi-mi:ACTC1(display_short)|uniprotkb:ACTC(gene name synonym)|uniprotkb:Alpha-cardiac actin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484786|imex:IM-26985-357 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q12824|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|rcsb pdb:5AJ1|rcsb pdb:5GJK|rcsb pdb:5L7A|rcsb pdb:5L7B|go:"GO:0007049"(cell cycle)|rcsb pdb:6AX5|go:"GO:0007399"(nervous system development)|rcsb pdb:6KAG|rcsb pdb:6KZ7|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6UCH|reactome:R-HSA-3214858|go:"GO:0008285"(negative regulation of cell population proliferation)|reactome:R-HSA-8939243|go:"GO:0015074"(DNA integration)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035060"(brahma complex)|go:"GO:0039692"(single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1900110"(negative regulation of histone H3-K9 dimethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR006939(SNF5/SMARCB1/INI1)|interpro:IPR017393(SWI/SNF chromatin-remodeling complex, component hSNF5/Ini1)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|refseq:NP_001007469.1|refseq:NP_003064.2|ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|ensembl:ENST00000618915(transcript)|ensembl:ENST00000644036(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0001741"(XY body)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-27550N refseq:NP_005150.1|ensembl:ENSG00000159251(gene)|ensembl:ENST00000290378(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005869"(dynactin complex)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030175"(filopodium)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031674"(I band)|go:"GO:0033275"(actin-myosin filament sliding)|go:"GO:0042493"|go:"GO:0044297"(cell body)|go:"GO:0045471"(response to ethanol)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0060047"(heart contraction)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090131"(mesenchyme migration)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR020902|interpro:IPR043129|mint:P68032|reactome:R-HSA-390522|reactome:R-HSA-8980692|reactome:R-HSA-9013026 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I9606 rogid:U/lKYqWUWMSC3fBHFaAcgzfk+3w9606 rigid:enWTmGjOUGt2tOv4q1fUv/rvjdU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q12824 uniprotkb:Q8WUB8 intact:EBI-358419|uniprotkb:O75784|uniprotkb:O95474|uniprotkb:Q38GA1|uniprotkb:Q76N08|uniprotkb:Q9UBH2|ensembl:ENSP00000479330|ensembl:ENSP00000494049|uniprotkb:Q17S11 intact:EBI-716462|uniprotkb:Q2YDA3|uniprotkb:Q9BXD2|uniprotkb:Q53HG8|uniprotkb:Q9NV26|ensembl:ENSP00000341805 psi-mi:snf5_human(display_long)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:INI1(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:BAF47(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym) psi-mi:phf10_human(display_long)|uniprotkb:XAP135(gene name synonym)|uniprotkb:PHF10(gene name)|psi-mi:PHF10(display_short)|uniprotkb:BAF45A(gene name synonym)|uniprotkb:BRG1-associated factor 45a(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484786|imex:IM-26985-357 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q12824|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|rcsb pdb:5AJ1|rcsb pdb:5GJK|rcsb pdb:5L7A|rcsb pdb:5L7B|go:"GO:0007049"(cell cycle)|rcsb pdb:6AX5|go:"GO:0007399"(nervous system development)|rcsb pdb:6KAG|rcsb pdb:6KZ7|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6UCH|reactome:R-HSA-3214858|go:"GO:0008285"(negative regulation of cell population proliferation)|reactome:R-HSA-8939243|go:"GO:0015074"(DNA integration)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035060"(brahma complex)|go:"GO:0039692"(single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1900110"(negative regulation of histone H3-K9 dimethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR006939(SNF5/SMARCB1/INI1)|interpro:IPR017393(SWI/SNF chromatin-remodeling complex, component hSNF5/Ini1)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|refseq:NP_001007469.1|refseq:NP_003064.2|ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|ensembl:ENST00000618915(transcript)|ensembl:ENST00000644036(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0001741"(XY body)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-27550N refseq:NP_060758.2|refseq:NP_579866.2|ensembl:ENSG00000130024(gene)|ensembl:ENST00000339209(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071564"(npBAF complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR038045|mint:Q8WUB8 - - comment:"author score: 37" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I9606 rogid:QppOFkomM0Lm/7EjW4Fov8NhB049606 rigid:enWTmGjOUGt2tOv4q1fUv/rvjdU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q12824 uniprotkb:Q92782 intact:EBI-358419|uniprotkb:O75784|uniprotkb:O95474|uniprotkb:Q38GA1|uniprotkb:Q76N08|uniprotkb:Q9UBH2|ensembl:ENSP00000479330|ensembl:ENSP00000494049|uniprotkb:Q17S11 intact:EBI-726953|uniprotkb:B3KSY8|uniprotkb:Q08AJ0 psi-mi:snf5_human(display_long)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:INI1(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:BAF47(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym) psi-mi:dpf1_human(display_long)|uniprotkb:D4, zinc and double PHD fingers family 1(gene name synonym)|uniprotkb:DPF1(gene name)|psi-mi:DPF1(display_short)|uniprotkb:NEUD4(gene name synonym)|uniprotkb:BAF45B(gene name synonym)|uniprotkb:BRG1-associated factor 45B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484786|imex:IM-26985-357 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q12824|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|rcsb pdb:5AJ1|rcsb pdb:5GJK|rcsb pdb:5L7A|rcsb pdb:5L7B|go:"GO:0007049"(cell cycle)|rcsb pdb:6AX5|go:"GO:0007399"(nervous system development)|rcsb pdb:6KAG|rcsb pdb:6KZ7|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6UCH|reactome:R-HSA-3214858|go:"GO:0008285"(negative regulation of cell population proliferation)|reactome:R-HSA-8939243|go:"GO:0015074"(DNA integration)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035060"(brahma complex)|go:"GO:0039692"(single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1900110"(negative regulation of histone H3-K9 dimethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR006939(SNF5/SMARCB1/INI1)|interpro:IPR017393(SWI/SNF chromatin-remodeling complex, component hSNF5/Ini1)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|refseq:NP_001007469.1|refseq:NP_003064.2|ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|ensembl:ENST00000618915(transcript)|ensembl:ENST00000644036(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0001741"(XY body)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-27550N refseq:NP_001128627.1|refseq:NP_001128628.1|refseq:NP_004638.2|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR019787|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071565"(nBAF complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|mint:Q92782|interpro:IPR025750|refseq:NP_001276907.1|interpro:IPR038046 - - comment:"author score: 50" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I9606 rogid:WnpwDXkyVSACQWBHcW9Rcj12O/o9606 rigid:enWTmGjOUGt2tOv4q1fUv/rvjdU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q12824 uniprotkb:Q92784 intact:EBI-358419|uniprotkb:O75784|uniprotkb:O95474|uniprotkb:Q38GA1|uniprotkb:Q76N08|uniprotkb:Q9UBH2|ensembl:ENSP00000479330|ensembl:ENSP00000494049|uniprotkb:Q17S11 intact:EBI-16355309|ensembl:ENSP00000450518|uniprotkb:A8MSI3|uniprotkb:B7Z276|uniprotkb:F5H575|uniprotkb:Q32UJ0|uniprotkb:Q6P9E6|uniprotkb:Q6ZT41|uniprotkb:Q9H7Y5 psi-mi:snf5_human(display_long)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:INI1(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:BAF47(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym) psi-mi:dpf3_human(display_long)|uniprotkb:DPF3(gene name)|psi-mi:DPF3(display_short)|uniprotkb:BAF45C(gene name synonym)|uniprotkb:BRG1-associated factor 45C(gene name synonym)|uniprotkb:CERD4(gene name synonym)|uniprotkb:Zinc finger protein cer-d4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484786|imex:IM-26985-357 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q12824|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|rcsb pdb:5AJ1|rcsb pdb:5GJK|rcsb pdb:5L7A|rcsb pdb:5L7B|go:"GO:0007049"(cell cycle)|rcsb pdb:6AX5|go:"GO:0007399"(nervous system development)|rcsb pdb:6KAG|rcsb pdb:6KZ7|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6UCH|reactome:R-HSA-3214858|go:"GO:0008285"(negative regulation of cell population proliferation)|reactome:R-HSA-8939243|go:"GO:0015074"(DNA integration)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035060"(brahma complex)|go:"GO:0039692"(single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1900110"(negative regulation of histone H3-K9 dimethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR006939(SNF5/SMARCB1/INI1)|interpro:IPR017393(SWI/SNF chromatin-remodeling complex, component hSNF5/Ini1)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|refseq:NP_001007469.1|refseq:NP_003064.2|ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|ensembl:ENST00000618915(transcript)|ensembl:ENST00000644036(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0001741"(XY body)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-27550N ensembl:ENSG00000205683(gene)|ensembl:ENST00000556509(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071565"(nBAF complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR019787|interpro:IPR025750|interpro:IPR036236|interpro:IPR038047|mint:Q92784|rcsb pdb:2KWJ|rcsb pdb:2KWK|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:5I3L|rcsb pdb:5SZB|rcsb pdb:5SZC|go:"GO:0007399"(nervous system development)|dip:DIP-59245N|refseq:NP_001267471.1|refseq:NP_001267472.1|refseq:NP_001267473.1|refseq:NP_036206.3|refseq:XP_016877159.1|refseq:XP_016877160.1 - - comment:"author score: 51" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I9606 rogid:O97+tk0b//PukSNQS/JTPszyqbU9606 rigid:enWTmGjOUGt2tOv4q1fUv/rvjdU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q12824 uniprotkb:O75177 intact:EBI-358419|uniprotkb:O75784|uniprotkb:O95474|uniprotkb:Q38GA1|uniprotkb:Q76N08|uniprotkb:Q9UBH2|ensembl:ENSP00000479330|ensembl:ENSP00000494049|uniprotkb:Q17S11 intact:EBI-744674|uniprotkb:Q5JXJ3|uniprotkb:Q8NE69|uniprotkb:Q9BR55|uniprotkb:Q9H4K6|uniprotkb:A6NNE3|uniprotkb:A8K620|uniprotkb:B3KWR8|uniprotkb:Q6MZV9|uniprotkb:Q6NTH3|uniprotkb:Q6XYD9|uniprotkb:E1P5H7|ensembl:ENSP00000333012 psi-mi:snf5_human(display_long)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:INI1(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:BAF47(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym) psi-mi:crest_human(display_long)|uniprotkb:SYT homolog 1(gene name synonym)|uniprotkb:KIAA0693(gene name synonym)|uniprotkb:SS18L1(gene name)|psi-mi:SS18L1(display_short)|uniprotkb:CREST(gene name synonym)|uniprotkb:SS18-like protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484786|imex:IM-26985-357 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q12824|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|rcsb pdb:5AJ1|rcsb pdb:5GJK|rcsb pdb:5L7A|rcsb pdb:5L7B|go:"GO:0007049"(cell cycle)|rcsb pdb:6AX5|go:"GO:0007399"(nervous system development)|rcsb pdb:6KAG|rcsb pdb:6KZ7|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6UCH|reactome:R-HSA-3214858|go:"GO:0008285"(negative regulation of cell population proliferation)|reactome:R-HSA-8939243|go:"GO:0015074"(DNA integration)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035060"(brahma complex)|go:"GO:0039692"(single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1900110"(negative regulation of histone H3-K9 dimethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR006939(SNF5/SMARCB1/INI1)|interpro:IPR017393(SWI/SNF chromatin-remodeling complex, component hSNF5/Ini1)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|refseq:NP_001007469.1|refseq:NP_003064.2|ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|ensembl:ENST00000618915(transcript)|ensembl:ENST00000644036(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0001741"(XY body)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-27550N refseq:NP_945173.1|refseq:XP_011527066.1|refseq:XP_011527069.1|ensembl:ENSG00000184402(gene)|ensembl:ENST00000331758(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0016358"(dendrite development)|go:"GO:0016604"(nuclear body)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0071565"(nBAF complex)|interpro:IPR007726(SSXT)|interpro:IPR044779|mint:O75177|refseq:NP_001288707.1|refseq:XP_005260448.1 - - comment:"author score: 65" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I9606 rogid:A7XGgvW0Roha0A4GgF5VvOC7dYs9606 rigid:enWTmGjOUGt2tOv4q1fUv/rvjdU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q12824 uniprotkb:Q15532 intact:EBI-358419|uniprotkb:O75784|uniprotkb:O95474|uniprotkb:Q38GA1|uniprotkb:Q76N08|uniprotkb:Q9UBH2|ensembl:ENSP00000479330|ensembl:ENSP00000494049|uniprotkb:Q17S11 intact:EBI-2560599|uniprotkb:Q4VAX1|uniprotkb:Q16404|uniprotkb:B0YJ95|uniprotkb:Q9BXC6|ensembl:ENSP00000414516 psi-mi:snf5_human(display_long)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:INI1(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:BAF47(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym) psi-mi:ssxt_human(display_long)|uniprotkb:SS18(gene name)|psi-mi:SS18(display_short)|uniprotkb:SSXT(gene name synonym)|uniprotkb:SYT(gene name synonym)|uniprotkb:Synovial sarcoma translocated to X chromosome protein(gene name synonym)|uniprotkb:Protein SYT(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484786|imex:IM-26985-357 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q12824|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|rcsb pdb:5AJ1|rcsb pdb:5GJK|rcsb pdb:5L7A|rcsb pdb:5L7B|go:"GO:0007049"(cell cycle)|rcsb pdb:6AX5|go:"GO:0007399"(nervous system development)|rcsb pdb:6KAG|rcsb pdb:6KZ7|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6UCH|reactome:R-HSA-3214858|go:"GO:0008285"(negative regulation of cell population proliferation)|reactome:R-HSA-8939243|go:"GO:0015074"(DNA integration)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035060"(brahma complex)|go:"GO:0039692"(single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1900110"(negative regulation of histone H3-K9 dimethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR006939(SNF5/SMARCB1/INI1)|interpro:IPR017393(SWI/SNF chromatin-remodeling complex, component hSNF5/Ini1)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|refseq:NP_001007469.1|refseq:NP_003064.2|ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|ensembl:ENST00000618915(transcript)|ensembl:ENST00000644036(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0001741"(XY body)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-27550N refseq:NP_001007560.1|refseq:NP_001295130.1|refseq:NP_005628.2|ensembl:ENSG00000141380(gene)|ensembl:ENST00000415083(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0071564"(npBAF complex)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR007726(SSXT)|interpro:IPR044779|mint:Q15532|ensembl:ENST00000269137|ensembl:ENSP00000269137|ensembl:ENSP00000414516 - - comment:"author score: 65" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I9606 rogid:qECbpt+KgdXXqUWQnrsL7rwxznQ9606 rigid:enWTmGjOUGt2tOv4q1fUv/rvjdU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q12824 uniprotkb:Q9NPI1 intact:EBI-358419|uniprotkb:O75784|uniprotkb:O95474|uniprotkb:Q38GA1|uniprotkb:Q76N08|uniprotkb:Q9UBH2|ensembl:ENSP00000479330|ensembl:ENSP00000494049|uniprotkb:Q17S11 intact:EBI-711221|uniprotkb:Q4VC09|uniprotkb:Q8N2L9|uniprotkb:Q96KA4|uniprotkb:Q9BV48|uniprotkb:Q9UH59|intact:EBI-2560548|ensembl:ENSP00000378180 psi-mi:snf5_human(display_long)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:INI1(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:BAF47(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym) psi-mi:brd7_human(display_long)|uniprotkb:75 kDa bromodomain protein(gene name synonym)|uniprotkb:Protein CELTIX-1(gene name synonym)|uniprotkb:BRD7(gene name)|psi-mi:BRD7(display_short)|uniprotkb:BP75(gene name synonym)|uniprotkb:CELTIX1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484786|imex:IM-26985-357 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q12824|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|rcsb pdb:5AJ1|rcsb pdb:5GJK|rcsb pdb:5L7A|rcsb pdb:5L7B|go:"GO:0007049"(cell cycle)|rcsb pdb:6AX5|go:"GO:0007399"(nervous system development)|rcsb pdb:6KAG|rcsb pdb:6KZ7|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6UCH|reactome:R-HSA-3214858|go:"GO:0008285"(negative regulation of cell population proliferation)|reactome:R-HSA-8939243|go:"GO:0015074"(DNA integration)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035060"(brahma complex)|go:"GO:0039692"(single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1900110"(negative regulation of histone H3-K9 dimethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR006939(SNF5/SMARCB1/INI1)|interpro:IPR017393(SWI/SNF chromatin-remodeling complex, component hSNF5/Ini1)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|refseq:NP_001007469.1|refseq:NP_003064.2|ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|ensembl:ENST00000618915(transcript)|ensembl:ENST00000644036(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0001741"(XY body)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-27550N refseq:NP_001167455.1|refseq:NP_037395.2|dip:DIP-32509N|ensembl:ENSG00000166164(gene)|ensembl:ENST00000394688(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001487(Bromodomain)|interpro:IPR021900|interpro:IPR036427|mint:Q9NPI1|rcsb pdb:2I7K|rcsb pdb:5MQ1|rcsb pdb:6PPA|rcsb pdb:6V0Q|rcsb pdb:6V16|rcsb pdb:6V17|rcsb pdb:6V1E|rcsb pdb:6V1F|rcsb pdb:6V1H|reactome:R-HSA-6804758 - - comment:"author score: 78" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I9606 rogid:F1N3XsdbpPy8TgHdMLSmnhdKNYs9606 rigid:enWTmGjOUGt2tOv4q1fUv/rvjdU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q12824 uniprotkb:Q4VC05 intact:EBI-358419|uniprotkb:O75784|uniprotkb:O95474|uniprotkb:Q38GA1|uniprotkb:Q76N08|uniprotkb:Q9UBH2|ensembl:ENSP00000479330|ensembl:ENSP00000494049|uniprotkb:Q17S11 intact:EBI-359917|uniprotkb:Q13843|uniprotkb:B4DJN6|uniprotkb:B7ZB21|uniprotkb:Q14CT7|intact:EBI-2560561|ensembl:ENSP00000261822|ensembl:ENSP00000489305 psi-mi:snf5_human(display_long)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:INI1(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:BAF47(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym) psi-mi:bcl7a_human(display_long)|uniprotkb:BCL7A(gene name)|psi-mi:BCL7A(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484786|imex:IM-26985-357 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q12824|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|rcsb pdb:5AJ1|rcsb pdb:5GJK|rcsb pdb:5L7A|rcsb pdb:5L7B|go:"GO:0007049"(cell cycle)|rcsb pdb:6AX5|go:"GO:0007399"(nervous system development)|rcsb pdb:6KAG|rcsb pdb:6KZ7|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6UCH|reactome:R-HSA-3214858|go:"GO:0008285"(negative regulation of cell population proliferation)|reactome:R-HSA-8939243|go:"GO:0015074"(DNA integration)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035060"(brahma complex)|go:"GO:0039692"(single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1900110"(negative regulation of histone H3-K9 dimethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR006939(SNF5/SMARCB1/INI1)|interpro:IPR017393(SWI/SNF chromatin-remodeling complex, component hSNF5/Ini1)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|refseq:NP_001007469.1|refseq:NP_003064.2|ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|ensembl:ENST00000618915(transcript)|ensembl:ENST00000644036(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0001741"(XY body)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-27550N refseq:NP_001019979.1|refseq:NP_066273.1|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR006804(BCL7, N-terminal)|mint:Q4VC05|ensembl:ENSG00000110987(gene)|ensembl:ENSG00000282873(gene)|ensembl:ENST00000261822(transcript)|ensembl:ENST00000635403(transcript)|dip:DIP-27608N - - comment:"author score: 95" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I9606 rogid:ZEtiQWH57T+t+gCMVVPHAJUO10w9606 rigid:enWTmGjOUGt2tOv4q1fUv/rvjdU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q12824 uniprotkb:O96019 intact:EBI-358419|uniprotkb:O75784|uniprotkb:O95474|uniprotkb:Q38GA1|uniprotkb:Q76N08|uniprotkb:Q9UBH2|ensembl:ENSP00000479330|ensembl:ENSP00000494049|uniprotkb:Q17S11 intact:EBI-355018|uniprotkb:Q8TAE5|uniprotkb:Q9BVS8|uniprotkb:Q9H0W6|uniprotkb:B3KMN1|uniprotkb:D3DNR9|ensembl:ENSP00000397552 psi-mi:snf5_human(display_long)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:INI1(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:BAF47(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym) psi-mi:acl6a_human(display_long)|uniprotkb:53 kDa BRG1-associated factor A(gene name synonym)|uniprotkb:Actin-related protein Baf53a(gene name synonym)|uniprotkb:ArpNbeta(gene name synonym)|uniprotkb:BAF53A(gene name synonym)|uniprotkb:ACTL6A(gene name)|psi-mi:ACTL6A(display_short)|uniprotkb:BAF53(gene name synonym)|uniprotkb:INO80K(gene name synonym)|uniprotkb:INO80 complex subunit K(gene name synonym)|uniprotkb:BRG1-associated factor 53A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484786|imex:IM-26985-357 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q12824|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|rcsb pdb:5AJ1|rcsb pdb:5GJK|rcsb pdb:5L7A|rcsb pdb:5L7B|go:"GO:0007049"(cell cycle)|rcsb pdb:6AX5|go:"GO:0007399"(nervous system development)|rcsb pdb:6KAG|rcsb pdb:6KZ7|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6UCH|reactome:R-HSA-3214858|go:"GO:0008285"(negative regulation of cell population proliferation)|reactome:R-HSA-8939243|go:"GO:0015074"(DNA integration)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035060"(brahma complex)|go:"GO:0039692"(single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1900110"(negative regulation of histone H3-K9 dimethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR006939(SNF5/SMARCB1/INI1)|interpro:IPR017393(SWI/SNF chromatin-remodeling complex, component hSNF5/Ini1)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|refseq:NP_001007469.1|refseq:NP_003064.2|ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|ensembl:ENST00000618915(transcript)|ensembl:ENST00000644036(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0001741"(XY body)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-27550N refseq:NP_004292.1|refseq:NP_817126.1|refseq:NP_829888.1|ensembl:ENSG00000136518(gene)|ensembl:ENST00000429709(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0003407"(neural retina development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0021510"(spinal cord development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043044"|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0071564"(npBAF complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR043129|mint:O96019|rcsb pdb:6LTJ|reactome:R-HSA-3214847|reactome:R-HSA-3214858|go:"GO:0000785"(chromatin)|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8939243|ensembl:ENST00000392662|ensembl:ENSP00000376430|ensembl:ENSP00000397552|ensembl:ENST00000450518|ensembl:ENSP00000394014|dip:DIP-27565N - - comment:"author score: 123" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I9606 rogid:FV8zvQxf2aeHbwFNUpo9JOpj5U49606 rigid:enWTmGjOUGt2tOv4q1fUv/rvjdU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q12824 uniprotkb:P51532 intact:EBI-358419|uniprotkb:O75784|uniprotkb:O95474|uniprotkb:Q38GA1|uniprotkb:Q76N08|uniprotkb:Q9UBH2|ensembl:ENSP00000479330|ensembl:ENSP00000494049|uniprotkb:Q17S11 intact:EBI-302489|uniprotkb:O95052|uniprotkb:Q9HBD3|uniprotkb:B1A8Z4|uniprotkb:B1A8Z5|uniprotkb:B1A8Z6|uniprotkb:B1A8Z7|uniprotkb:E9PBR8|ensembl:ENSP00000343896|ensembl:ENSP00000395654 psi-mi:snf5_human(display_long)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:INI1(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:BAF47(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym) psi-mi:smca4_human(display_long)|uniprotkb:SMARCA4(gene name)|psi-mi:SMARCA4(display_short)|uniprotkb:BRG1(gene name synonym)|uniprotkb:SNF2B(gene name synonym)|uniprotkb:SNF2L4(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA4(gene name synonym)|uniprotkb:SNF2-beta(gene name synonym)|uniprotkb:BAF190A(gene name synonym)|uniprotkb:Mitotic growth and transcription activator(gene name synonym)|uniprotkb:Protein BRG-1(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4(gene name synonym)|uniprotkb:Protein brahma homolog 1(gene name synonym)|uniprotkb:BRG1-associated factor 190A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484786|imex:IM-26985-357 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q12824|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|rcsb pdb:5AJ1|rcsb pdb:5GJK|rcsb pdb:5L7A|rcsb pdb:5L7B|go:"GO:0007049"(cell cycle)|rcsb pdb:6AX5|go:"GO:0007399"(nervous system development)|rcsb pdb:6KAG|rcsb pdb:6KZ7|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6UCH|reactome:R-HSA-3214858|go:"GO:0008285"(negative regulation of cell population proliferation)|reactome:R-HSA-8939243|go:"GO:0015074"(DNA integration)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035060"(brahma complex)|go:"GO:0039692"(single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1900110"(negative regulation of histone H3-K9 dimethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR006939(SNF5/SMARCB1/INI1)|interpro:IPR017393(SWI/SNF chromatin-remodeling complex, component hSNF5/Ini1)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|refseq:NP_001007469.1|refseq:NP_003064.2|ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|ensembl:ENST00000618915(transcript)|ensembl:ENST00000644036(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0001741"(XY body)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-27550N refseq:NP_001122316.1|refseq:NP_003063.2|refseq:NP_001122317.1|refseq:NP_001122318.1|refseq:NP_001122319.1|refseq:NP_001122320.1|dip:DIP-24249N|refseq:XP_016882654.1|refseq:XP_016882655.1|refseq:XP_016882656.1|refseq:XP_016882657.1|ensembl:ENSG00000127616(gene)|ensembl:ENST00000344626(transcript)|ensembl:ENST00000429416(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0002039"(p53 binding)|go:"GO:0003407"(neural retina development)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030100|interpro:IPR036427|interpro:IPR037259|interpro:IPR038718|mint:P51532|rcsb pdb:2GRC|rcsb pdb:2H60|rcsb pdb:3UVD|rcsb pdb:5DKD|rcsb pdb:5EA1|rcsb pdb:6BGH|rcsb pdb:6HR2|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6SY2|rcsb pdb:6ZS2|reactome:R-HSA-1266695|reactome:R-HSA-201722|reactome:R-HSA-3214858|reactome:R-HSA-3247509|reactome:R-HSA-8939243|reactome:R-HSA-9619665 - - comment:"author score: 135" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I9606 rogid:Ztr+2IXfAxueSUaNYG2A47HoMes9606 rigid:enWTmGjOUGt2tOv4q1fUv/rvjdU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q12824 uniprotkb:Q6STE5 intact:EBI-358419|uniprotkb:O75784|uniprotkb:O95474|uniprotkb:Q38GA1|uniprotkb:Q76N08|uniprotkb:Q9UBH2|ensembl:ENSP00000479330|ensembl:ENSP00000494049|uniprotkb:Q17S11 intact:EBI-465496|ensembl:ENSP00000262188|uniprotkb:Q75MJ2|uniprotkb:Q75MR8|uniprotkb:Q92926|uniprotkb:Q9BUH1|intact:EBI-488496|intact:EBI-1760029|uniprotkb:Q2YD86|uniprotkb:D3DX10 psi-mi:snf5_human(display_long)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:INI1(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:BAF47(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym) psi-mi:smrd3_human(display_long)|uniprotkb:SMARCD3(gene name)|psi-mi:SMARCD3(display_short)|uniprotkb:BAF60C(gene name synonym)|uniprotkb:60 kDa BRG-1/Brm-associated factor subunit C(gene name synonym)|uniprotkb:BRG1-associated factor 60C(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484786|imex:IM-26985-357 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q12824|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|rcsb pdb:5AJ1|rcsb pdb:5GJK|rcsb pdb:5L7A|rcsb pdb:5L7B|go:"GO:0007049"(cell cycle)|rcsb pdb:6AX5|go:"GO:0007399"(nervous system development)|rcsb pdb:6KAG|rcsb pdb:6KZ7|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6UCH|reactome:R-HSA-3214858|go:"GO:0008285"(negative regulation of cell population proliferation)|reactome:R-HSA-8939243|go:"GO:0015074"(DNA integration)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035060"(brahma complex)|go:"GO:0039692"(single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1900110"(negative regulation of histone H3-K9 dimethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR006939(SNF5/SMARCB1/INI1)|interpro:IPR017393(SWI/SNF chromatin-remodeling complex, component hSNF5/Ini1)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|refseq:NP_001007469.1|refseq:NP_003064.2|ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|ensembl:ENST00000618915(transcript)|ensembl:ENST00000644036(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0001741"(XY body)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-27550N ensembl:ENSG00000082014(gene)|ensembl:ENST00000262188(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003219"(cardiac right ventricle formation)|go:"GO:0003407"(neural retina development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR003121(SWIB/MDM2)|interpro:IPR019835|interpro:IPR036885|interpro:IPR038043|mint:Q6STE5|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|go:"GO:0016922"(nuclear receptor binding)|reactome:R-HSA-2426168|reactome:R-HSA-3214858|reactome:R-HSA-381340|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-8939243|reactome:R-HSA-9707564|reactome:R-HSA-9707616|reactome:R-HSA-2151201|refseq:NP_001003801.1|refseq:NP_001003802.1|refseq:NP_003069.2|dip:DIP-33012N - - comment:"author score: 142" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I9606 rogid:fCKGyz4ZneKj5VHia17wdMq6neI9606 rigid:enWTmGjOUGt2tOv4q1fUv/rvjdU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q12824 uniprotkb:Q8TAQ2 intact:EBI-358419|uniprotkb:O75784|uniprotkb:O95474|uniprotkb:Q38GA1|uniprotkb:Q76N08|uniprotkb:Q9UBH2|ensembl:ENSP00000479330|ensembl:ENSP00000494049|uniprotkb:Q17S11 intact:EBI-357418|ensembl:ENSP00000267064|uniprotkb:Q92923|uniprotkb:Q96E12|uniprotkb:Q96GY4|intact:EBI-1759986|intact:EBI-1965079|uniprotkb:F8VTJ5|uniprotkb:Q59GV3 psi-mi:snf5_human(display_long)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:INI1(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:BAF47(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym) psi-mi:smrc2_human(display_long)|uniprotkb:SMARCC2(gene name)|psi-mi:SMARCC2(display_short)|uniprotkb:BAF170(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2(gene name synonym)|uniprotkb:SWI/SNF complex 170 kDa subunit(gene name synonym)|uniprotkb:BRG1-associated factor 170(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484786|imex:IM-26985-357 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q12824|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|rcsb pdb:5AJ1|rcsb pdb:5GJK|rcsb pdb:5L7A|rcsb pdb:5L7B|go:"GO:0007049"(cell cycle)|rcsb pdb:6AX5|go:"GO:0007399"(nervous system development)|rcsb pdb:6KAG|rcsb pdb:6KZ7|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6UCH|reactome:R-HSA-3214858|go:"GO:0008285"(negative regulation of cell population proliferation)|reactome:R-HSA-8939243|go:"GO:0015074"(DNA integration)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035060"(brahma complex)|go:"GO:0039692"(single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1900110"(negative regulation of histone H3-K9 dimethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR006939(SNF5/SMARCB1/INI1)|interpro:IPR017393(SWI/SNF chromatin-remodeling complex, component hSNF5/Ini1)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|refseq:NP_001007469.1|refseq:NP_003064.2|ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|ensembl:ENST00000618915(transcript)|ensembl:ENST00000644036(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0001741"(XY body)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-27550N ensembl:ENSG00000139613(gene)|ensembl:ENST00000267064(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR000953(Chromo domain)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR032448|interpro:IPR032450|interpro:IPR032451|interpro:IPR036388|interpro:IPR036420|interpro:IPR038044|mint:Q8TAQ2|rcsb pdb:6KAG|rcsb pdb:6LTH|rcsb pdb:6LTJ|reactome:R-HSA-3214858|reactome:R-HSA-8939243|refseq:NP_003066.2|refseq:NP_001123892.1|refseq:NP_620706.1|refseq:NP_001317217.1|dip:DIP-27611N - - comment:"author score: 155" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I9606 rogid:60gIB3J1YI/FzqVCzdoSg1Oj3ME9606 rigid:enWTmGjOUGt2tOv4q1fUv/rvjdU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q12824 uniprotkb:Q92925 intact:EBI-358419|uniprotkb:O75784|uniprotkb:O95474|uniprotkb:Q38GA1|uniprotkb:Q76N08|uniprotkb:Q9UBH2|ensembl:ENSP00000479330|ensembl:ENSP00000494049|uniprotkb:Q17S11 intact:EBI-358441|uniprotkb:Q7L2I6|uniprotkb:Q9UHZ1|uniprotkb:A5PLL5|uniprotkb:A6NNQ7|uniprotkb:B4DV56|uniprotkb:B4E1R6|ensembl:ENSP00000392617 psi-mi:snf5_human(display_long)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:INI1(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:BAF47(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym) psi-mi:smrd2_human(display_long)|uniprotkb:PRO2451(orf name)|uniprotkb:SMARCD2(gene name)|psi-mi:SMARCD2(display_short)|uniprotkb:BAF60B(gene name synonym)|uniprotkb:60 kDa BRG-1/Brm-associated factor subunit B(gene name synonym)|uniprotkb:BRG1-associated factor 60B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484786|imex:IM-26985-357 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q12824|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|rcsb pdb:5AJ1|rcsb pdb:5GJK|rcsb pdb:5L7A|rcsb pdb:5L7B|go:"GO:0007049"(cell cycle)|rcsb pdb:6AX5|go:"GO:0007399"(nervous system development)|rcsb pdb:6KAG|rcsb pdb:6KZ7|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6UCH|reactome:R-HSA-3214858|go:"GO:0008285"(negative regulation of cell population proliferation)|reactome:R-HSA-8939243|go:"GO:0015074"(DNA integration)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035060"(brahma complex)|go:"GO:0039692"(single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1900110"(negative regulation of histone H3-K9 dimethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR006939(SNF5/SMARCB1/INI1)|interpro:IPR017393(SWI/SNF chromatin-remodeling complex, component hSNF5/Ini1)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|refseq:NP_001007469.1|refseq:NP_003064.2|ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|ensembl:ENST00000618915(transcript)|ensembl:ENST00000644036(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0001741"(XY body)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-27550N refseq:NP_001091896.1|dip:DIP-31182N|refseq:NP_001317369.1|ensembl:ENSG00000108604(gene)|ensembl:ENST00000448276(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR003121(SWIB/MDM2)|interpro:IPR019835|interpro:IPR030090|interpro:IPR036885|mint:Q92925|reactome:R-HSA-3214858|reactome:R-HSA-8939243 - - comment:"author score: 180" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I9606 rogid:n6YHBJ+cqEmVcXwMYsTZGOfL86A9606 rigid:enWTmGjOUGt2tOv4q1fUv/rvjdU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q12824 uniprotkb:Q96GM5 intact:EBI-358419|uniprotkb:O75784|uniprotkb:O95474|uniprotkb:Q38GA1|uniprotkb:Q76N08|uniprotkb:Q9UBH2|ensembl:ENSP00000479330|ensembl:ENSP00000494049|uniprotkb:Q17S11 intact:EBI-358489|intact:EBI-1760001|ensembl:ENSP00000378414|uniprotkb:Q92924|uniprotkb:Q9Y635|intact:EBI-1965109|uniprotkb:A6NN27|intact:EBI-28976725 psi-mi:snf5_human(display_long)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:INI1(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:BAF47(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym) psi-mi:smrd1_human(display_long)|uniprotkb:SMARCD1(gene name)|psi-mi:SMARCD1(display_short)|uniprotkb:BAF60A(gene name synonym)|uniprotkb:SWI/SNF complex 60 kDa subunit(gene name synonym)|uniprotkb:60 kDa BRG-1/Brm-associated factor subunit A(gene name synonym)|uniprotkb:BRG1-associated factor 60A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484786|imex:IM-26985-357 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q12824|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|rcsb pdb:5AJ1|rcsb pdb:5GJK|rcsb pdb:5L7A|rcsb pdb:5L7B|go:"GO:0007049"(cell cycle)|rcsb pdb:6AX5|go:"GO:0007399"(nervous system development)|rcsb pdb:6KAG|rcsb pdb:6KZ7|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6UCH|reactome:R-HSA-3214858|go:"GO:0008285"(negative regulation of cell population proliferation)|reactome:R-HSA-8939243|go:"GO:0015074"(DNA integration)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035060"(brahma complex)|go:"GO:0039692"(single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1900110"(negative regulation of histone H3-K9 dimethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR006939(SNF5/SMARCB1/INI1)|interpro:IPR017393(SWI/SNF chromatin-remodeling complex, component hSNF5/Ini1)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|refseq:NP_001007469.1|refseq:NP_003064.2|ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|ensembl:ENST00000618915(transcript)|ensembl:ENST00000644036(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0001741"(XY body)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-27550N ensembl:ENSG00000066117(gene)|ensembl:ENST00000394963(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048096"|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071564"(npBAF complex)|refseq:NP_003067.3|refseq:NP_620710.2|ensembl:ENST00000381513|ensembl:ENSP00000370924|ensembl:ENSP00000378414|go:"GO:0071565"(nBAF complex)|interpro:IPR003121(SWIB/MDM2)|interpro:IPR019835|interpro:IPR036885|interpro:IPR038041|mint:Q96GM5|rcsb pdb:6LTH|rcsb pdb:6LTJ|reactome:R-HSA-3214858|reactome:R-HSA-8939243|dip:DIP-33390N - - comment:"author score: 187" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I9606 rogid:cwqYnl+J8glG8YjW1ps77Dd105Y9606 rigid:enWTmGjOUGt2tOv4q1fUv/rvjdU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q12824 uniprotkb:Q92922 intact:EBI-358419|uniprotkb:O75784|uniprotkb:O95474|uniprotkb:Q38GA1|uniprotkb:Q76N08|uniprotkb:Q9UBH2|ensembl:ENSP00000479330|ensembl:ENSP00000494049|uniprotkb:Q17S11 intact:EBI-355653|uniprotkb:Q6P172|uniprotkb:Q8IWH2|uniprotkb:Q17RS0|ensembl:ENSP00000254480 psi-mi:snf5_human(display_long)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:INI1(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:BAF47(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym) psi-mi:smrc1_human(display_long)|uniprotkb:SMARCC1(gene name)|psi-mi:SMARCC1(display_short)|uniprotkb:BAF155(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1(gene name synonym)|uniprotkb:SWI/SNF complex 155 kDa subunit(gene name synonym)|uniprotkb:BRG1-associated factor 155(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484786|imex:IM-26985-357 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) mint:Q12824|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|rcsb pdb:5AJ1|rcsb pdb:5GJK|rcsb pdb:5L7A|rcsb pdb:5L7B|go:"GO:0007049"(cell cycle)|rcsb pdb:6AX5|go:"GO:0007399"(nervous system development)|rcsb pdb:6KAG|rcsb pdb:6KZ7|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6UCH|reactome:R-HSA-3214858|go:"GO:0008285"(negative regulation of cell population proliferation)|reactome:R-HSA-8939243|go:"GO:0015074"(DNA integration)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035060"(brahma complex)|go:"GO:0039692"(single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1900110"(negative regulation of histone H3-K9 dimethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR006939(SNF5/SMARCB1/INI1)|interpro:IPR017393(SWI/SNF chromatin-remodeling complex, component hSNF5/Ini1)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|refseq:NP_001007469.1|refseq:NP_003064.2|ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|ensembl:ENST00000618915(transcript)|ensembl:ENST00000644036(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0001741"(XY body)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-27550N refseq:NP_003065.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR000953(Chromo domain)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR030087|interpro:IPR032448|interpro:IPR032450|interpro:IPR032451|interpro:IPR036388|interpro:IPR036420|mint:Q92922|rcsb pdb:2YUS|rcsb pdb:5GJK|rcsb pdb:6KZ7|rcsb pdb:6YXO|rcsb pdb:6YXP|reactome:R-HSA-3214858|reactome:R-HSA-8939243|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|ensembl:ENSG00000173473(gene)|ensembl:ENST00000254480(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001741"(XY body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030850"(prostate gland development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|ensembl:ENSP00000254480|dip:DIP-27545N|dip:DIP-33044N - - comment:"author score: 199" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I9606 rogid:Uv0bjPkUICLtOXJcETUXDTLIQhY9606 rigid:enWTmGjOUGt2tOv4q1fUv/rvjdU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969G3 uniprotkb:Q68CP9 intact:EBI-455078|uniprotkb:O43539|uniprotkb:C0IMW4|uniprotkb:B3KMC1|uniprotkb:B4DFR4|uniprotkb:C0IMW5|uniprotkb:C0IMW7|uniprotkb:H7C3F6|ensembl:ENSP00000323967|ensembl:ENSP00000496094 intact:EBI-637818|uniprotkb:Q15KG9|uniprotkb:Q5EB51|uniprotkb:Q645I3|uniprotkb:Q6ZRY5|uniprotkb:Q7Z3I5|uniprotkb:Q86T28|uniprotkb:Q96SJ6|uniprotkb:Q9HCL5|ensembl:ENSP00000335044 psi-mi:smce1_human(display_long)|uniprotkb:BRG1-associated factor 57(gene name synonym)|uniprotkb:SMARCE1(gene name)|psi-mi:SMARCE1(display_short)|uniprotkb:BAF57(gene name synonym) psi-mi:arid2_human(display_long)|uniprotkb:BRG1-associated factor 200(gene name synonym)|uniprotkb:Zinc finger protein with activation potential(gene name synonym)|uniprotkb:Zipzap/p200(gene name synonym)|uniprotkb:ARID2(gene name)|psi-mi:ARID2(display_short)|uniprotkb:KIAA1557(gene name synonym)|uniprotkb:BAF200(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484885|imex:IM-26985-579 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003070.3|dip:DIP-27614N|dip:DIP-33041N|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR030089|interpro:IPR036910|mint:Q969G3|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:7CYU|reactome:R-HSA-3214858|reactome:R-HSA-8939243|ensembl:ENSG00000073584(gene)|ensembl:ENST00000348513(transcript)|ensembl:ENST00000643683(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex) refseq:NP_689854.2|ensembl:ENSG00000189079(gene)|ensembl:ENST00000334344(transcript)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042592"(homeostatic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0048568"(embryonic organ development)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR003150(DNA-binding RFX)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR036388|interpro:IPR036390|interpro:IPR036431|mint:Q68CP9|reactome:R-HSA-3214858|reactome:R-HSA-8939243|dip:DIP-33391N|refseq:NP_001334768.1|ensembl:ENSP00000335044 - - comment:"author score: 46" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wf7PrAelShE+8xAwb/UdWKWDkyE9606 rogid:7AJ6PqICERVZS+s3sZBIBODzs/I9606 rigid:O4u5PV0aFsoQWduNS+d0Um6pxzU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969G3 uniprotkb:Q86U86 intact:EBI-455078|uniprotkb:O43539|uniprotkb:C0IMW4|uniprotkb:B3KMC1|uniprotkb:B4DFR4|uniprotkb:C0IMW5|uniprotkb:C0IMW7|uniprotkb:H7C3F6|ensembl:ENSP00000323967|ensembl:ENSP00000496094 intact:EBI-637807|uniprotkb:Q9H2T3|uniprotkb:Q9H2T4|uniprotkb:Q9H2T5|uniprotkb:Q9H301|uniprotkb:Q9H314|uniprotkb:A1L381|uniprotkb:A1L382|uniprotkb:A4FUJ7|uniprotkb:Q1RMD1|uniprotkb:Q1RMD2|uniprotkb:Q96MS2|ensembl:ENSP00000296302 psi-mi:smce1_human(display_long)|uniprotkb:BRG1-associated factor 57(gene name synonym)|uniprotkb:SMARCE1(gene name)|psi-mi:SMARCE1(display_short)|uniprotkb:BAF57(gene name synonym) psi-mi:pb1_human(display_long)|uniprotkb:Polybromo-1D(gene name synonym)|uniprotkb:BRG1-associated factor 180(gene name synonym)|uniprotkb:PBRM1(gene name)|psi-mi:PBRM1(display_short)|uniprotkb:PB1(gene name synonym)|uniprotkb:BAF180(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484885|imex:IM-26985-579 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003070.3|dip:DIP-27614N|dip:DIP-33041N|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR030089|interpro:IPR036910|mint:Q969G3|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:7CYU|reactome:R-HSA-3214858|reactome:R-HSA-8939243|ensembl:ENSG00000073584(gene)|ensembl:ENST00000348513(transcript)|ensembl:ENST00000643683(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex) refseq:NP_060783.3|ensembl:ENSG00000163939(gene)|ensembl:ENST00000296302(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016586"(RSC-type complex)|go:"GO:0043044"|interpro:IPR001025(Bromo adjacent region)|interpro:IPR001487(Bromodomain)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR018359|interpro:IPR036427|interpro:IPR036910|interpro:IPR037382|interpro:IPR037968|interpro:IPR043151|mint:Q86U86|rcsb pdb:2KTB|rcsb pdb:3G0J|rcsb pdb:3HMF|rcsb pdb:3IU5|rcsb pdb:3IU6|rcsb pdb:3K2J|rcsb pdb:3LJW|rcsb pdb:3MB4|rcsb pdb:3TLP|rcsb pdb:4Q0N|rcsb pdb:4Q0O|rcsb pdb:4Y03|rcsb pdb:5E7D|rcsb pdb:5FH6|rcsb pdb:5FH7|rcsb pdb:5FH8|rcsb pdb:5HRV|rcsb pdb:5HRW|rcsb pdb:5HRX|rcsb pdb:5II1|rcsb pdb:5II2|rcsb pdb:5IID|rcsb pdb:6OXB|rcsb pdb:6ZN6|rcsb pdb:6ZNV|rcsb pdb:6ZS3|rcsb pdb:6ZS4|reactome:R-HSA-3214858|reactome:R-HSA-8939243|dip:DIP-33045N|refseq:XP_016862237.1|refseq:XP_016862238.1|refseq:XP_016862239.1|refseq:XP_016862246.1|refseq:XP_016862247.1|refseq:NP_851385.1 - - comment:"author score: 52" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wf7PrAelShE+8xAwb/UdWKWDkyE9606 rogid:nJp9kwLE9qxj6DcyEO8dUok6k/Q9606 rigid:O4u5PV0aFsoQWduNS+d0Um6pxzU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969G3 uniprotkb:Q8NFD5 intact:EBI-455078|uniprotkb:O43539|uniprotkb:C0IMW4|uniprotkb:B3KMC1|uniprotkb:B4DFR4|uniprotkb:C0IMW5|uniprotkb:C0IMW7|uniprotkb:H7C3F6|ensembl:ENSP00000323967|ensembl:ENSP00000496094 intact:EBI-679921|uniprotkb:Q5JRD1|uniprotkb:Q5VYC4|uniprotkb:Q8IZY8|uniprotkb:Q8TEV0|uniprotkb:Q8TF02|uniprotkb:Q99491|uniprotkb:Q9ULI5|intact:EBI-2560572|ensembl:ENSP00000055163 psi-mi:smce1_human(display_long)|uniprotkb:BRG1-associated factor 57(gene name synonym)|uniprotkb:SMARCE1(gene name)|psi-mi:SMARCE1(display_short)|uniprotkb:BAF57(gene name synonym) psi-mi:ari1b_human(display_long)|uniprotkb:BAF250B(gene name synonym)|uniprotkb:Osa homolog 2(gene name synonym)|uniprotkb:p250R(gene name synonym)|uniprotkb:BRG1-binding protein hELD/OSA1(gene name synonym)|uniprotkb:BRG1-associated factor 250b(gene name synonym)|uniprotkb:ARID1B(gene name)|psi-mi:ARID1B(display_short)|uniprotkb:DAN15(gene name synonym)|uniprotkb:KIAA1235(gene name synonym)|uniprotkb:OSA2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484885|imex:IM-26985-579 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003070.3|dip:DIP-27614N|dip:DIP-33041N|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR030089|interpro:IPR036910|mint:Q969G3|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:7CYU|reactome:R-HSA-3214858|reactome:R-HSA-8939243|ensembl:ENSG00000073584(gene)|ensembl:ENST00000348513(transcript)|ensembl:ENST00000643683(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex) refseq:NP_001333742.1|refseq:NP_059989.2|refseq:NP_065783.3|ensembl:ENSG00000049618(gene)|ensembl:ENST00000350026(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0035060"(brahma complex)|go:"GO:0043044"|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048096"|go:"GO:0071565"(nBAF complex)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR021906|interpro:IPR033388|interpro:IPR036431|interpro:IPR038040|mint:Q8NFD5|rcsb pdb:2CXY|rcsb pdb:2EH9|reactome:R-HSA-3214858|reactome:R-HSA-8939243 - - comment:"author score: 86" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wf7PrAelShE+8xAwb/UdWKWDkyE9606 rogid:BeWhuwPk5f6HN+yasFEJRpkbM6A9606 rigid:O4u5PV0aFsoQWduNS+d0Um6pxzU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969G3 uniprotkb:O14497 intact:EBI-455078|uniprotkb:O43539|uniprotkb:C0IMW4|uniprotkb:B3KMC1|uniprotkb:B4DFR4|uniprotkb:C0IMW5|uniprotkb:C0IMW7|uniprotkb:H7C3F6|ensembl:ENSP00000323967|ensembl:ENSP00000496094 intact:EBI-637887|intact:EBI-28988406|ensembl:ENSP00000320485|uniprotkb:D3DPL1|uniprotkb:Q53FK9|uniprotkb:Q5T0W1|uniprotkb:Q5T0W2|uniprotkb:Q5T0W3|uniprotkb:Q8NFD6|uniprotkb:Q96T89|uniprotkb:Q9BY33|uniprotkb:Q9HBJ5|uniprotkb:Q9UPZ1 psi-mi:smce1_human(display_long)|uniprotkb:BRG1-associated factor 57(gene name synonym)|uniprotkb:SMARCE1(gene name)|psi-mi:SMARCE1(display_short)|uniprotkb:BAF57(gene name synonym) psi-mi:ari1a_human(display_long)|uniprotkb:hELD(gene name synonym)|uniprotkb:SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1(gene name synonym)|uniprotkb:SWI/SNF complex protein p270(gene name synonym)|uniprotkb:B120(gene name synonym)|uniprotkb:SWI-like protein(gene name synonym)|uniprotkb:Osa homolog 1(gene name synonym)|uniprotkb:BRG1-associated factor 250(gene name synonym)|uniprotkb:BRG1-associated factor 250a(gene name synonym)|uniprotkb:ARID1A(gene name)|psi-mi:ARID1A(display_short)|uniprotkb:C1orf4(gene name synonym)|uniprotkb:SMARCF1(gene name synonym)|uniprotkb:OSA1(gene name synonym)|uniprotkb:BAF250(gene name synonym)|uniprotkb:BAF250A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484885|imex:IM-26985-579 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003070.3|dip:DIP-27614N|dip:DIP-33041N|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR030089|interpro:IPR036910|mint:Q969G3|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:7CYU|reactome:R-HSA-3214858|reactome:R-HSA-8939243|ensembl:ENSG00000073584(gene)|ensembl:ENST00000348513(transcript)|ensembl:ENST00000643683(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex) reactome:R-HSA-3214858|reactome:R-HSA-8939243|go:"GO:0005634"(nucleus)|ensembl:ENSG00000117713(gene)|go:"GO:0005654"(nucleoplasm)|ensembl:ENST00000324856(transcript)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0035060"(brahma complex)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043044"|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048096"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR001606(AT-rich interaction region)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021906|interpro:IPR030094|interpro:IPR033388|interpro:IPR036431|mint:O14497|rcsb pdb:1RYU|rcsb pdb:6LTH|rcsb pdb:6LTJ|refseq:NP_006006.3|refseq:NP_624361.1|dip:DIP-33016N|ensembl:ENSP00000320485|ensembl:ENST00000374152|ensembl:ENSP00000363267|ensembl:ENST00000457599|ensembl:ENSP00000387636 - - comment:"author score: 136" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wf7PrAelShE+8xAwb/UdWKWDkyE9606 rogid:C3ZRlsnBUZV6SBEbISRImamhzoQ9606 rigid:O4u5PV0aFsoQWduNS+d0Um6pxzU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969G3 uniprotkb:P51531 intact:EBI-455078|uniprotkb:O43539|uniprotkb:C0IMW4|uniprotkb:B3KMC1|uniprotkb:B4DFR4|uniprotkb:C0IMW5|uniprotkb:C0IMW7|uniprotkb:H7C3F6|ensembl:ENSP00000323967|ensembl:ENSP00000496094 intact:EBI-679562|uniprotkb:B1ALG3|uniprotkb:B1ALG4|uniprotkb:D3DRH4|uniprotkb:D3DRH5|ensembl:ENSP00000265773|ensembl:ENSP00000371638 psi-mi:smce1_human(display_long)|uniprotkb:BRG1-associated factor 57(gene name synonym)|uniprotkb:SMARCE1(gene name)|psi-mi:SMARCE1(display_short)|uniprotkb:BAF57(gene name synonym) psi-mi:smca2_human(display_long)|uniprotkb:ATP-dependent helicase SMARCA2(gene name synonym)|uniprotkb:SNF2-alpha(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2(gene name synonym)|uniprotkb:SMARCA2(gene name)|psi-mi:SMARCA2(display_short)|uniprotkb:BRM(gene name synonym)|uniprotkb:SNF2A(gene name synonym)|uniprotkb:SNF2L2(gene name synonym)|uniprotkb:BAF190B(gene name synonym)|uniprotkb:Protein brahma homolog(gene name synonym)|uniprotkb:BRG1-associated factor 190B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484885|imex:IM-26985-579 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003070.3|dip:DIP-27614N|dip:DIP-33041N|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR030089|interpro:IPR036910|mint:Q969G3|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:7CYU|reactome:R-HSA-3214858|reactome:R-HSA-8939243|ensembl:ENSG00000073584(gene)|ensembl:ENST00000348513(transcript)|ensembl:ENST00000643683(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex) refseq:NP_003061.3|refseq:NP_620614.2|refseq:NP_001276325.1|refseq:NP_001276326.1|dip:DIP-29005N|ensembl:ENSG00000080503(gene)|ensembl:ENST00000349721(transcript)|ensembl:ENST00000382203(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007286"(spermatid development)|go:"GO:0007399"(nervous system development)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070615"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030088|interpro:IPR036427|interpro:IPR037259|interpro:IPR038718|mint:P51531|rcsb pdb:2DAT|rcsb pdb:4QY4|rcsb pdb:5DKC|rcsb pdb:5DKH|rcsb pdb:6EG2|rcsb pdb:6EG3|rcsb pdb:6HAX|rcsb pdb:6HAY|rcsb pdb:6HAZ|reactome:R-HSA-3214858|reactome:R-HSA-8939243 - - comment:"author score: 139" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wf7PrAelShE+8xAwb/UdWKWDkyE9606 rogid:DmQot4h4SmtqmUGBgF5ictTah289606 rigid:O4u5PV0aFsoQWduNS+d0Um6pxzU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969G3 uniprotkb:Q8WUZ0 intact:EBI-455078|uniprotkb:O43539|uniprotkb:C0IMW4|uniprotkb:B3KMC1|uniprotkb:B4DFR4|uniprotkb:C0IMW5|uniprotkb:C0IMW7|uniprotkb:H7C3F6|ensembl:ENSP00000323967|ensembl:ENSP00000496094 intact:EBI-7850114|intact:EBI-28969068|ensembl:ENSP00000215115|uniprotkb:Q6PD89|uniprotkb:O43770|intact:MINT-4535839 psi-mi:smce1_human(display_long)|uniprotkb:BRG1-associated factor 57(gene name synonym)|uniprotkb:SMARCE1(gene name)|psi-mi:SMARCE1(display_short)|uniprotkb:BAF57(gene name synonym) psi-mi:bcl7c_human(display_long)|uniprotkb:BCL7C(gene name)|psi-mi:BCL7C(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484885|imex:IM-26985-579 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003070.3|dip:DIP-27614N|dip:DIP-33041N|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR030089|interpro:IPR036910|mint:Q969G3|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:7CYU|reactome:R-HSA-3214858|reactome:R-HSA-8939243|ensembl:ENSG00000073584(gene)|ensembl:ENST00000348513(transcript)|ensembl:ENST00000643683(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex) refseq:NP_001273455.1|ensembl:ENSP00000215115|ensembl:ENST00000380317|ensembl:ENSP00000369674|ensembl:ENSG00000099385(gene)|ensembl:ENST00000215115(transcript)|go:"GO:0006915"(apoptotic process)|interpro:IPR006804(BCL7, N-terminal)|mint:Q8WUZ0|refseq:NP_004756.2 - - comment:mint|comment:homomint|function:May play an anti-apoptotic role|comment:"author score: 179" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wf7PrAelShE+8xAwb/UdWKWDkyE9606 rogid:XuyDhxOhWHNVXmgi/WXLmCvKn409606 rigid:O4u5PV0aFsoQWduNS+d0Um6pxzU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969G3 uniprotkb:Q8WUB8 intact:EBI-455078|uniprotkb:O43539|uniprotkb:C0IMW4|uniprotkb:B3KMC1|uniprotkb:B4DFR4|uniprotkb:C0IMW5|uniprotkb:C0IMW7|uniprotkb:H7C3F6|ensembl:ENSP00000323967|ensembl:ENSP00000496094 intact:EBI-716462|uniprotkb:Q2YDA3|uniprotkb:Q9BXD2|uniprotkb:Q53HG8|uniprotkb:Q9NV26|ensembl:ENSP00000341805 psi-mi:smce1_human(display_long)|uniprotkb:BRG1-associated factor 57(gene name synonym)|uniprotkb:SMARCE1(gene name)|psi-mi:SMARCE1(display_short)|uniprotkb:BAF57(gene name synonym) psi-mi:phf10_human(display_long)|uniprotkb:XAP135(gene name synonym)|uniprotkb:PHF10(gene name)|psi-mi:PHF10(display_short)|uniprotkb:BAF45A(gene name synonym)|uniprotkb:BRG1-associated factor 45a(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484885|imex:IM-26985-579 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003070.3|dip:DIP-27614N|dip:DIP-33041N|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR030089|interpro:IPR036910|mint:Q969G3|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:7CYU|reactome:R-HSA-3214858|reactome:R-HSA-8939243|ensembl:ENSG00000073584(gene)|ensembl:ENST00000348513(transcript)|ensembl:ENST00000643683(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex) refseq:NP_060758.2|refseq:NP_579866.2|ensembl:ENSG00000130024(gene)|ensembl:ENST00000339209(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071564"(npBAF complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR038045|mint:Q8WUB8 - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wf7PrAelShE+8xAwb/UdWKWDkyE9606 rogid:QppOFkomM0Lm/7EjW4Fov8NhB049606 rigid:O4u5PV0aFsoQWduNS+d0Um6pxzU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969G3 uniprotkb:Q92784 intact:EBI-455078|uniprotkb:O43539|uniprotkb:C0IMW4|uniprotkb:B3KMC1|uniprotkb:B4DFR4|uniprotkb:C0IMW5|uniprotkb:C0IMW7|uniprotkb:H7C3F6|ensembl:ENSP00000323967|ensembl:ENSP00000496094 intact:EBI-16355309|ensembl:ENSP00000450518|uniprotkb:A8MSI3|uniprotkb:B7Z276|uniprotkb:F5H575|uniprotkb:Q32UJ0|uniprotkb:Q6P9E6|uniprotkb:Q6ZT41|uniprotkb:Q9H7Y5 psi-mi:smce1_human(display_long)|uniprotkb:BRG1-associated factor 57(gene name synonym)|uniprotkb:SMARCE1(gene name)|psi-mi:SMARCE1(display_short)|uniprotkb:BAF57(gene name synonym) psi-mi:dpf3_human(display_long)|uniprotkb:DPF3(gene name)|psi-mi:DPF3(display_short)|uniprotkb:BAF45C(gene name synonym)|uniprotkb:BRG1-associated factor 45C(gene name synonym)|uniprotkb:CERD4(gene name synonym)|uniprotkb:Zinc finger protein cer-d4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484885|imex:IM-26985-579 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003070.3|dip:DIP-27614N|dip:DIP-33041N|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR030089|interpro:IPR036910|mint:Q969G3|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:7CYU|reactome:R-HSA-3214858|reactome:R-HSA-8939243|ensembl:ENSG00000073584(gene)|ensembl:ENST00000348513(transcript)|ensembl:ENST00000643683(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex) ensembl:ENSG00000205683(gene)|ensembl:ENST00000556509(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071565"(nBAF complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR019787|interpro:IPR025750|interpro:IPR036236|interpro:IPR038047|mint:Q92784|rcsb pdb:2KWJ|rcsb pdb:2KWK|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:5I3L|rcsb pdb:5SZB|rcsb pdb:5SZC|go:"GO:0007399"(nervous system development)|dip:DIP-59245N|refseq:NP_001267471.1|refseq:NP_001267472.1|refseq:NP_001267473.1|refseq:NP_036206.3|refseq:XP_016877159.1|refseq:XP_016877160.1 - - comment:"author score: 38" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wf7PrAelShE+8xAwb/UdWKWDkyE9606 rogid:O97+tk0b//PukSNQS/JTPszyqbU9606 rigid:O4u5PV0aFsoQWduNS+d0Um6pxzU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969G3 uniprotkb:Q15532 intact:EBI-455078|uniprotkb:O43539|uniprotkb:C0IMW4|uniprotkb:B3KMC1|uniprotkb:B4DFR4|uniprotkb:C0IMW5|uniprotkb:C0IMW7|uniprotkb:H7C3F6|ensembl:ENSP00000323967|ensembl:ENSP00000496094 intact:EBI-2560599|uniprotkb:Q4VAX1|uniprotkb:Q16404|uniprotkb:B0YJ95|uniprotkb:Q9BXC6|ensembl:ENSP00000414516 psi-mi:smce1_human(display_long)|uniprotkb:BRG1-associated factor 57(gene name synonym)|uniprotkb:SMARCE1(gene name)|psi-mi:SMARCE1(display_short)|uniprotkb:BAF57(gene name synonym) psi-mi:ssxt_human(display_long)|uniprotkb:SS18(gene name)|psi-mi:SS18(display_short)|uniprotkb:SSXT(gene name synonym)|uniprotkb:SYT(gene name synonym)|uniprotkb:Synovial sarcoma translocated to X chromosome protein(gene name synonym)|uniprotkb:Protein SYT(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484885|imex:IM-26985-579 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003070.3|dip:DIP-27614N|dip:DIP-33041N|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR030089|interpro:IPR036910|mint:Q969G3|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:7CYU|reactome:R-HSA-3214858|reactome:R-HSA-8939243|ensembl:ENSG00000073584(gene)|ensembl:ENST00000348513(transcript)|ensembl:ENST00000643683(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex) refseq:NP_001007560.1|refseq:NP_001295130.1|refseq:NP_005628.2|ensembl:ENSG00000141380(gene)|ensembl:ENST00000415083(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042493"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0071564"(npBAF complex)|go:"GO:0097150"(neuronal stem cell population maintenance)|interpro:IPR007726(SSXT)|interpro:IPR044779|mint:Q15532|ensembl:ENST00000269137|ensembl:ENSP00000269137|ensembl:ENSP00000414516 - - comment:"author score: 55" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wf7PrAelShE+8xAwb/UdWKWDkyE9606 rogid:qECbpt+KgdXXqUWQnrsL7rwxznQ9606 rigid:O4u5PV0aFsoQWduNS+d0Um6pxzU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969G3 uniprotkb:Q92782 intact:EBI-455078|uniprotkb:O43539|uniprotkb:C0IMW4|uniprotkb:B3KMC1|uniprotkb:B4DFR4|uniprotkb:C0IMW5|uniprotkb:C0IMW7|uniprotkb:H7C3F6|ensembl:ENSP00000323967|ensembl:ENSP00000496094 intact:EBI-726953|uniprotkb:B3KSY8|uniprotkb:Q08AJ0 psi-mi:smce1_human(display_long)|uniprotkb:BRG1-associated factor 57(gene name synonym)|uniprotkb:SMARCE1(gene name)|psi-mi:SMARCE1(display_short)|uniprotkb:BAF57(gene name synonym) psi-mi:dpf1_human(display_long)|uniprotkb:D4, zinc and double PHD fingers family 1(gene name synonym)|uniprotkb:DPF1(gene name)|psi-mi:DPF1(display_short)|uniprotkb:NEUD4(gene name synonym)|uniprotkb:BAF45B(gene name synonym)|uniprotkb:BRG1-associated factor 45B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484885|imex:IM-26985-579 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003070.3|dip:DIP-27614N|dip:DIP-33041N|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR030089|interpro:IPR036910|mint:Q969G3|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:7CYU|reactome:R-HSA-3214858|reactome:R-HSA-8939243|ensembl:ENSG00000073584(gene)|ensembl:ENST00000348513(transcript)|ensembl:ENST00000643683(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex) refseq:NP_001128627.1|refseq:NP_001128628.1|refseq:NP_004638.2|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR019787|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0071565"(nBAF complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|mint:Q92782|interpro:IPR025750|refseq:NP_001276907.1|interpro:IPR038046 - - comment:"author score: 55" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wf7PrAelShE+8xAwb/UdWKWDkyE9606 rogid:WnpwDXkyVSACQWBHcW9Rcj12O/o9606 rigid:O4u5PV0aFsoQWduNS+d0Um6pxzU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969G3 uniprotkb:O75177 intact:EBI-455078|uniprotkb:O43539|uniprotkb:C0IMW4|uniprotkb:B3KMC1|uniprotkb:B4DFR4|uniprotkb:C0IMW5|uniprotkb:C0IMW7|uniprotkb:H7C3F6|ensembl:ENSP00000323967|ensembl:ENSP00000496094 intact:EBI-744674|uniprotkb:Q5JXJ3|uniprotkb:Q8NE69|uniprotkb:Q9BR55|uniprotkb:Q9H4K6|uniprotkb:A6NNE3|uniprotkb:A8K620|uniprotkb:B3KWR8|uniprotkb:Q6MZV9|uniprotkb:Q6NTH3|uniprotkb:Q6XYD9|uniprotkb:E1P5H7|ensembl:ENSP00000333012 psi-mi:smce1_human(display_long)|uniprotkb:BRG1-associated factor 57(gene name synonym)|uniprotkb:SMARCE1(gene name)|psi-mi:SMARCE1(display_short)|uniprotkb:BAF57(gene name synonym) psi-mi:crest_human(display_long)|uniprotkb:SYT homolog 1(gene name synonym)|uniprotkb:KIAA0693(gene name synonym)|uniprotkb:SS18L1(gene name)|psi-mi:SS18L1(display_short)|uniprotkb:CREST(gene name synonym)|uniprotkb:SS18-like protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484885|imex:IM-26985-579 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003070.3|dip:DIP-27614N|dip:DIP-33041N|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR030089|interpro:IPR036910|mint:Q969G3|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:7CYU|reactome:R-HSA-3214858|reactome:R-HSA-8939243|ensembl:ENSG00000073584(gene)|ensembl:ENST00000348513(transcript)|ensembl:ENST00000643683(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex) refseq:NP_945173.1|refseq:XP_011527066.1|refseq:XP_011527069.1|ensembl:ENSG00000184402(gene)|ensembl:ENST00000331758(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0016358"(dendrite development)|go:"GO:0016604"(nuclear body)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0071565"(nBAF complex)|interpro:IPR007726(SSXT)|interpro:IPR044779|mint:O75177|refseq:NP_001288707.1|refseq:XP_005260448.1 - - comment:"author score: 58" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wf7PrAelShE+8xAwb/UdWKWDkyE9606 rogid:A7XGgvW0Roha0A4GgF5VvOC7dYs9606 rigid:O4u5PV0aFsoQWduNS+d0Um6pxzU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969G3 uniprotkb:Q4VC05 intact:EBI-455078|uniprotkb:O43539|uniprotkb:C0IMW4|uniprotkb:B3KMC1|uniprotkb:B4DFR4|uniprotkb:C0IMW5|uniprotkb:C0IMW7|uniprotkb:H7C3F6|ensembl:ENSP00000323967|ensembl:ENSP00000496094 intact:EBI-359917|uniprotkb:Q13843|uniprotkb:B4DJN6|uniprotkb:B7ZB21|uniprotkb:Q14CT7|intact:EBI-2560561|ensembl:ENSP00000261822|ensembl:ENSP00000489305 psi-mi:smce1_human(display_long)|uniprotkb:BRG1-associated factor 57(gene name synonym)|uniprotkb:SMARCE1(gene name)|psi-mi:SMARCE1(display_short)|uniprotkb:BAF57(gene name synonym) psi-mi:bcl7a_human(display_long)|uniprotkb:BCL7A(gene name)|psi-mi:BCL7A(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484885|imex:IM-26985-579 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003070.3|dip:DIP-27614N|dip:DIP-33041N|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR030089|interpro:IPR036910|mint:Q969G3|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:7CYU|reactome:R-HSA-3214858|reactome:R-HSA-8939243|ensembl:ENSG00000073584(gene)|ensembl:ENST00000348513(transcript)|ensembl:ENST00000643683(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex) refseq:NP_001019979.1|refseq:NP_066273.1|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR006804(BCL7, N-terminal)|mint:Q4VC05|ensembl:ENSG00000110987(gene)|ensembl:ENSG00000282873(gene)|ensembl:ENST00000261822(transcript)|ensembl:ENST00000635403(transcript)|dip:DIP-27608N - - comment:"author score: 71" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wf7PrAelShE+8xAwb/UdWKWDkyE9606 rogid:ZEtiQWH57T+t+gCMVVPHAJUO10w9606 rigid:O4u5PV0aFsoQWduNS+d0Um6pxzU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969G3 uniprotkb:Q9NPI1 intact:EBI-455078|uniprotkb:O43539|uniprotkb:C0IMW4|uniprotkb:B3KMC1|uniprotkb:B4DFR4|uniprotkb:C0IMW5|uniprotkb:C0IMW7|uniprotkb:H7C3F6|ensembl:ENSP00000323967|ensembl:ENSP00000496094 intact:EBI-711221|uniprotkb:Q4VC09|uniprotkb:Q8N2L9|uniprotkb:Q96KA4|uniprotkb:Q9BV48|uniprotkb:Q9UH59|intact:EBI-2560548|ensembl:ENSP00000378180 psi-mi:smce1_human(display_long)|uniprotkb:BRG1-associated factor 57(gene name synonym)|uniprotkb:SMARCE1(gene name)|psi-mi:SMARCE1(display_short)|uniprotkb:BAF57(gene name synonym) psi-mi:brd7_human(display_long)|uniprotkb:75 kDa bromodomain protein(gene name synonym)|uniprotkb:Protein CELTIX-1(gene name synonym)|uniprotkb:BRD7(gene name)|psi-mi:BRD7(display_short)|uniprotkb:BP75(gene name synonym)|uniprotkb:CELTIX1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484885|imex:IM-26985-579 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003070.3|dip:DIP-27614N|dip:DIP-33041N|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR030089|interpro:IPR036910|mint:Q969G3|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:7CYU|reactome:R-HSA-3214858|reactome:R-HSA-8939243|ensembl:ENSG00000073584(gene)|ensembl:ENST00000348513(transcript)|ensembl:ENST00000643683(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex) refseq:NP_001167455.1|refseq:NP_037395.2|dip:DIP-32509N|ensembl:ENSG00000166164(gene)|ensembl:ENST00000394688(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002039"(p53 binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001487(Bromodomain)|interpro:IPR021900|interpro:IPR036427|mint:Q9NPI1|rcsb pdb:2I7K|rcsb pdb:5MQ1|rcsb pdb:6PPA|rcsb pdb:6V0Q|rcsb pdb:6V16|rcsb pdb:6V17|rcsb pdb:6V1E|rcsb pdb:6V1F|rcsb pdb:6V1H|reactome:R-HSA-6804758 - - comment:"author score: 72" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wf7PrAelShE+8xAwb/UdWKWDkyE9606 rogid:F1N3XsdbpPy8TgHdMLSmnhdKNYs9606 rigid:O4u5PV0aFsoQWduNS+d0Um6pxzU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969G3 uniprotkb:O96019 intact:EBI-455078|uniprotkb:O43539|uniprotkb:C0IMW4|uniprotkb:B3KMC1|uniprotkb:B4DFR4|uniprotkb:C0IMW5|uniprotkb:C0IMW7|uniprotkb:H7C3F6|ensembl:ENSP00000323967|ensembl:ENSP00000496094 intact:EBI-355018|uniprotkb:Q8TAE5|uniprotkb:Q9BVS8|uniprotkb:Q9H0W6|uniprotkb:B3KMN1|uniprotkb:D3DNR9|ensembl:ENSP00000397552 psi-mi:smce1_human(display_long)|uniprotkb:BRG1-associated factor 57(gene name synonym)|uniprotkb:SMARCE1(gene name)|psi-mi:SMARCE1(display_short)|uniprotkb:BAF57(gene name synonym) psi-mi:acl6a_human(display_long)|uniprotkb:53 kDa BRG1-associated factor A(gene name synonym)|uniprotkb:Actin-related protein Baf53a(gene name synonym)|uniprotkb:ArpNbeta(gene name synonym)|uniprotkb:BAF53A(gene name synonym)|uniprotkb:ACTL6A(gene name)|psi-mi:ACTL6A(display_short)|uniprotkb:BAF53(gene name synonym)|uniprotkb:INO80K(gene name synonym)|uniprotkb:INO80 complex subunit K(gene name synonym)|uniprotkb:BRG1-associated factor 53A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484885|imex:IM-26985-579 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003070.3|dip:DIP-27614N|dip:DIP-33041N|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR030089|interpro:IPR036910|mint:Q969G3|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:7CYU|reactome:R-HSA-3214858|reactome:R-HSA-8939243|ensembl:ENSG00000073584(gene)|ensembl:ENST00000348513(transcript)|ensembl:ENST00000643683(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex) refseq:NP_004292.1|refseq:NP_817126.1|refseq:NP_829888.1|ensembl:ENSG00000136518(gene)|ensembl:ENST00000429709(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0003407"(neural retina development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0021510"(spinal cord development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043044"|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0071564"(npBAF complex)|interpro:IPR004000(Actin/actin-like)|interpro:IPR004001(Actin, conserved site)|interpro:IPR043129|mint:O96019|rcsb pdb:6LTJ|reactome:R-HSA-3214847|reactome:R-HSA-3214858|go:"GO:0000785"(chromatin)|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8939243|ensembl:ENST00000392662|ensembl:ENSP00000376430|ensembl:ENSP00000397552|ensembl:ENST00000450518|ensembl:ENSP00000394014|dip:DIP-27565N - - comment:"author score: 117" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wf7PrAelShE+8xAwb/UdWKWDkyE9606 rogid:FV8zvQxf2aeHbwFNUpo9JOpj5U49606 rigid:O4u5PV0aFsoQWduNS+d0Um6pxzU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969G3 uniprotkb:Q6STE5 intact:EBI-455078|uniprotkb:O43539|uniprotkb:C0IMW4|uniprotkb:B3KMC1|uniprotkb:B4DFR4|uniprotkb:C0IMW5|uniprotkb:C0IMW7|uniprotkb:H7C3F6|ensembl:ENSP00000323967|ensembl:ENSP00000496094 intact:EBI-465496|ensembl:ENSP00000262188|uniprotkb:Q75MJ2|uniprotkb:Q75MR8|uniprotkb:Q92926|uniprotkb:Q9BUH1|intact:EBI-488496|intact:EBI-1760029|uniprotkb:Q2YD86|uniprotkb:D3DX10 psi-mi:smce1_human(display_long)|uniprotkb:BRG1-associated factor 57(gene name synonym)|uniprotkb:SMARCE1(gene name)|psi-mi:SMARCE1(display_short)|uniprotkb:BAF57(gene name synonym) psi-mi:smrd3_human(display_long)|uniprotkb:SMARCD3(gene name)|psi-mi:SMARCD3(display_short)|uniprotkb:BAF60C(gene name synonym)|uniprotkb:60 kDa BRG-1/Brm-associated factor subunit C(gene name synonym)|uniprotkb:BRG1-associated factor 60C(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484885|imex:IM-26985-579 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003070.3|dip:DIP-27614N|dip:DIP-33041N|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR030089|interpro:IPR036910|mint:Q969G3|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:7CYU|reactome:R-HSA-3214858|reactome:R-HSA-8939243|ensembl:ENSG00000073584(gene)|ensembl:ENST00000348513(transcript)|ensembl:ENST00000643683(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex) ensembl:ENSG00000082014(gene)|ensembl:ENST00000262188(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0003139"(secondary heart field specification)|go:"GO:0003219"(cardiac right ventricle formation)|go:"GO:0003407"(neural retina development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0042692"(muscle cell differentiation)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR003121(SWIB/MDM2)|interpro:IPR019835|interpro:IPR036885|interpro:IPR038043|mint:Q6STE5|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|go:"GO:0016922"(nuclear receptor binding)|reactome:R-HSA-2426168|reactome:R-HSA-3214858|reactome:R-HSA-381340|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-8939243|reactome:R-HSA-9707564|reactome:R-HSA-9707616|reactome:R-HSA-2151201|refseq:NP_001003801.1|refseq:NP_001003802.1|refseq:NP_003069.2|dip:DIP-33012N - - comment:"author score: 126" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wf7PrAelShE+8xAwb/UdWKWDkyE9606 rogid:fCKGyz4ZneKj5VHia17wdMq6neI9606 rigid:O4u5PV0aFsoQWduNS+d0Um6pxzU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969G3 uniprotkb:P51532 intact:EBI-455078|uniprotkb:O43539|uniprotkb:C0IMW4|uniprotkb:B3KMC1|uniprotkb:B4DFR4|uniprotkb:C0IMW5|uniprotkb:C0IMW7|uniprotkb:H7C3F6|ensembl:ENSP00000323967|ensembl:ENSP00000496094 intact:EBI-302489|uniprotkb:O95052|uniprotkb:Q9HBD3|uniprotkb:B1A8Z4|uniprotkb:B1A8Z5|uniprotkb:B1A8Z6|uniprotkb:B1A8Z7|uniprotkb:E9PBR8|ensembl:ENSP00000343896|ensembl:ENSP00000395654 psi-mi:smce1_human(display_long)|uniprotkb:BRG1-associated factor 57(gene name synonym)|uniprotkb:SMARCE1(gene name)|psi-mi:SMARCE1(display_short)|uniprotkb:BAF57(gene name synonym) psi-mi:smca4_human(display_long)|uniprotkb:SMARCA4(gene name)|psi-mi:SMARCA4(display_short)|uniprotkb:BRG1(gene name synonym)|uniprotkb:SNF2B(gene name synonym)|uniprotkb:SNF2L4(gene name synonym)|uniprotkb:ATP-dependent helicase SMARCA4(gene name synonym)|uniprotkb:SNF2-beta(gene name synonym)|uniprotkb:BAF190A(gene name synonym)|uniprotkb:Mitotic growth and transcription activator(gene name synonym)|uniprotkb:Protein BRG-1(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4(gene name synonym)|uniprotkb:Protein brahma homolog 1(gene name synonym)|uniprotkb:BRG1-associated factor 190A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484885|imex:IM-26985-579 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003070.3|dip:DIP-27614N|dip:DIP-33041N|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR030089|interpro:IPR036910|mint:Q969G3|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:7CYU|reactome:R-HSA-3214858|reactome:R-HSA-8939243|ensembl:ENSG00000073584(gene)|ensembl:ENST00000348513(transcript)|ensembl:ENST00000643683(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex) refseq:NP_001122316.1|refseq:NP_003063.2|refseq:NP_001122317.1|refseq:NP_001122318.1|refseq:NP_001122319.1|refseq:NP_001122320.1|dip:DIP-24249N|refseq:XP_016882654.1|refseq:XP_016882655.1|refseq:XP_016882656.1|refseq:XP_016882657.1|ensembl:ENSG00000127616(gene)|ensembl:ENST00000344626(transcript)|ensembl:ENST00000429416(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0002039"(p53 binding)|go:"GO:0003407"(neural retina development)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016020"(membrane)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0070615"|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:1902895"(positive regulation of miRNA transcription)|interpro:IPR000330(SNF2-related)|interpro:IPR001487(Bromodomain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR006576(BRK)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014012(Helicase/SANT-associated, DNA binding)|interpro:IPR014978(QLQ)|interpro:IPR018359|interpro:IPR027417|interpro:IPR029295|interpro:IPR030100|interpro:IPR036427|interpro:IPR037259|interpro:IPR038718|mint:P51532|rcsb pdb:2GRC|rcsb pdb:2H60|rcsb pdb:3UVD|rcsb pdb:5DKD|rcsb pdb:5EA1|rcsb pdb:6BGH|rcsb pdb:6HR2|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6SY2|rcsb pdb:6ZS2|reactome:R-HSA-1266695|reactome:R-HSA-201722|reactome:R-HSA-3214858|reactome:R-HSA-3247509|reactome:R-HSA-8939243|reactome:R-HSA-9619665 - - comment:"author score: 131" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wf7PrAelShE+8xAwb/UdWKWDkyE9606 rogid:Ztr+2IXfAxueSUaNYG2A47HoMes9606 rigid:O4u5PV0aFsoQWduNS+d0Um6pxzU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969G3 uniprotkb:Q96GM5 intact:EBI-455078|uniprotkb:O43539|uniprotkb:C0IMW4|uniprotkb:B3KMC1|uniprotkb:B4DFR4|uniprotkb:C0IMW5|uniprotkb:C0IMW7|uniprotkb:H7C3F6|ensembl:ENSP00000323967|ensembl:ENSP00000496094 intact:EBI-358489|intact:EBI-1760001|ensembl:ENSP00000378414|uniprotkb:Q92924|uniprotkb:Q9Y635|intact:EBI-1965109|uniprotkb:A6NN27|intact:EBI-28976725 psi-mi:smce1_human(display_long)|uniprotkb:BRG1-associated factor 57(gene name synonym)|uniprotkb:SMARCE1(gene name)|psi-mi:SMARCE1(display_short)|uniprotkb:BAF57(gene name synonym) psi-mi:smrd1_human(display_long)|uniprotkb:SMARCD1(gene name)|psi-mi:SMARCD1(display_short)|uniprotkb:BAF60A(gene name synonym)|uniprotkb:SWI/SNF complex 60 kDa subunit(gene name synonym)|uniprotkb:60 kDa BRG-1/Brm-associated factor subunit A(gene name synonym)|uniprotkb:BRG1-associated factor 60A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484885|imex:IM-26985-579 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003070.3|dip:DIP-27614N|dip:DIP-33041N|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR030089|interpro:IPR036910|mint:Q969G3|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:7CYU|reactome:R-HSA-3214858|reactome:R-HSA-8939243|ensembl:ENSG00000073584(gene)|ensembl:ENST00000348513(transcript)|ensembl:ENST00000643683(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex) ensembl:ENSG00000066117(gene)|ensembl:ENST00000394963(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048096"|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071564"(npBAF complex)|refseq:NP_003067.3|refseq:NP_620710.2|ensembl:ENST00000381513|ensembl:ENSP00000370924|ensembl:ENSP00000378414|go:"GO:0071565"(nBAF complex)|interpro:IPR003121(SWIB/MDM2)|interpro:IPR019835|interpro:IPR036885|interpro:IPR038041|mint:Q96GM5|rcsb pdb:6LTH|rcsb pdb:6LTJ|reactome:R-HSA-3214858|reactome:R-HSA-8939243|dip:DIP-33390N - - comment:"author score: 164" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wf7PrAelShE+8xAwb/UdWKWDkyE9606 rogid:cwqYnl+J8glG8YjW1ps77Dd105Y9606 rigid:O4u5PV0aFsoQWduNS+d0Um6pxzU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969G3 uniprotkb:Q8TAQ2 intact:EBI-455078|uniprotkb:O43539|uniprotkb:C0IMW4|uniprotkb:B3KMC1|uniprotkb:B4DFR4|uniprotkb:C0IMW5|uniprotkb:C0IMW7|uniprotkb:H7C3F6|ensembl:ENSP00000323967|ensembl:ENSP00000496094 intact:EBI-357418|ensembl:ENSP00000267064|uniprotkb:Q92923|uniprotkb:Q96E12|uniprotkb:Q96GY4|intact:EBI-1759986|intact:EBI-1965079|uniprotkb:F8VTJ5|uniprotkb:Q59GV3 psi-mi:smce1_human(display_long)|uniprotkb:BRG1-associated factor 57(gene name synonym)|uniprotkb:SMARCE1(gene name)|psi-mi:SMARCE1(display_short)|uniprotkb:BAF57(gene name synonym) psi-mi:smrc2_human(display_long)|uniprotkb:SMARCC2(gene name)|psi-mi:SMARCC2(display_short)|uniprotkb:BAF170(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2(gene name synonym)|uniprotkb:SWI/SNF complex 170 kDa subunit(gene name synonym)|uniprotkb:BRG1-associated factor 170(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484885|imex:IM-26985-579 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003070.3|dip:DIP-27614N|dip:DIP-33041N|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR030089|interpro:IPR036910|mint:Q969G3|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:7CYU|reactome:R-HSA-3214858|reactome:R-HSA-8939243|ensembl:ENSG00000073584(gene)|ensembl:ENST00000348513(transcript)|ensembl:ENST00000643683(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex) ensembl:ENSG00000139613(gene)|ensembl:ENST00000267064(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR000953(Chromo domain)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR032448|interpro:IPR032450|interpro:IPR032451|interpro:IPR036388|interpro:IPR036420|interpro:IPR038044|mint:Q8TAQ2|rcsb pdb:6KAG|rcsb pdb:6LTH|rcsb pdb:6LTJ|reactome:R-HSA-3214858|reactome:R-HSA-8939243|refseq:NP_003066.2|refseq:NP_001123892.1|refseq:NP_620706.1|refseq:NP_001317217.1|dip:DIP-27611N - - comment:"author score: 176" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wf7PrAelShE+8xAwb/UdWKWDkyE9606 rogid:60gIB3J1YI/FzqVCzdoSg1Oj3ME9606 rigid:O4u5PV0aFsoQWduNS+d0Um6pxzU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969G3 uniprotkb:Q92925 intact:EBI-455078|uniprotkb:O43539|uniprotkb:C0IMW4|uniprotkb:B3KMC1|uniprotkb:B4DFR4|uniprotkb:C0IMW5|uniprotkb:C0IMW7|uniprotkb:H7C3F6|ensembl:ENSP00000323967|ensembl:ENSP00000496094 intact:EBI-358441|uniprotkb:Q7L2I6|uniprotkb:Q9UHZ1|uniprotkb:A5PLL5|uniprotkb:A6NNQ7|uniprotkb:B4DV56|uniprotkb:B4E1R6|ensembl:ENSP00000392617 psi-mi:smce1_human(display_long)|uniprotkb:BRG1-associated factor 57(gene name synonym)|uniprotkb:SMARCE1(gene name)|psi-mi:SMARCE1(display_short)|uniprotkb:BAF57(gene name synonym) psi-mi:smrd2_human(display_long)|uniprotkb:PRO2451(orf name)|uniprotkb:SMARCD2(gene name)|psi-mi:SMARCD2(display_short)|uniprotkb:BAF60B(gene name synonym)|uniprotkb:60 kDa BRG-1/Brm-associated factor subunit B(gene name synonym)|uniprotkb:BRG1-associated factor 60B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484885|imex:IM-26985-579 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003070.3|dip:DIP-27614N|dip:DIP-33041N|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR030089|interpro:IPR036910|mint:Q969G3|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:7CYU|reactome:R-HSA-3214858|reactome:R-HSA-8939243|ensembl:ENSG00000073584(gene)|ensembl:ENST00000348513(transcript)|ensembl:ENST00000643683(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex) refseq:NP_001091896.1|dip:DIP-31182N|refseq:NP_001317369.1|ensembl:ENSG00000108604(gene)|ensembl:ENST00000448276(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR003121(SWIB/MDM2)|interpro:IPR019835|interpro:IPR030090|interpro:IPR036885|mint:Q92925|reactome:R-HSA-3214858|reactome:R-HSA-8939243 - - comment:"author score: 177" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wf7PrAelShE+8xAwb/UdWKWDkyE9606 rogid:n6YHBJ+cqEmVcXwMYsTZGOfL86A9606 rigid:O4u5PV0aFsoQWduNS+d0Um6pxzU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969G3 uniprotkb:Q92922 intact:EBI-455078|uniprotkb:O43539|uniprotkb:C0IMW4|uniprotkb:B3KMC1|uniprotkb:B4DFR4|uniprotkb:C0IMW5|uniprotkb:C0IMW7|uniprotkb:H7C3F6|ensembl:ENSP00000323967|ensembl:ENSP00000496094 intact:EBI-355653|uniprotkb:Q6P172|uniprotkb:Q8IWH2|uniprotkb:Q17RS0|ensembl:ENSP00000254480 psi-mi:smce1_human(display_long)|uniprotkb:BRG1-associated factor 57(gene name synonym)|uniprotkb:SMARCE1(gene name)|psi-mi:SMARCE1(display_short)|uniprotkb:BAF57(gene name synonym) psi-mi:smrc1_human(display_long)|uniprotkb:SMARCC1(gene name)|psi-mi:SMARCC1(display_short)|uniprotkb:BAF155(gene name synonym)|uniprotkb:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1(gene name synonym)|uniprotkb:SWI/SNF complex 155 kDa subunit(gene name synonym)|uniprotkb:BRG1-associated factor 155(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484885|imex:IM-26985-579 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003070.3|dip:DIP-27614N|dip:DIP-33041N|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR030089|interpro:IPR036910|mint:Q969G3|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:7CYU|reactome:R-HSA-3214858|reactome:R-HSA-8939243|ensembl:ENSG00000073584(gene)|ensembl:ENST00000348513(transcript)|ensembl:ENST00000643683(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex) refseq:NP_003065.3|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|interpro:IPR000953(Chromo domain)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR007526(SWIRM)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|interpro:IPR017930|interpro:IPR030087|interpro:IPR032448|interpro:IPR032450|interpro:IPR032451|interpro:IPR036388|interpro:IPR036420|mint:Q92922|rcsb pdb:2YUS|rcsb pdb:5GJK|rcsb pdb:6KZ7|rcsb pdb:6YXO|rcsb pdb:6YXP|reactome:R-HSA-3214858|reactome:R-HSA-8939243|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|ensembl:ENSG00000173473(gene)|ensembl:ENST00000254480(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001741"(XY body)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007399"(nervous system development)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030850"(prostate gland development)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043044"|ensembl:ENSP00000254480|dip:DIP-27545N|dip:DIP-33044N - - comment:"author score: 218" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wf7PrAelShE+8xAwb/UdWKWDkyE9606 rogid:Uv0bjPkUICLtOXJcETUXDTLIQhY9606 rigid:O4u5PV0aFsoQWduNS+d0Um6pxzU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969G3 uniprotkb:Q12824 intact:EBI-455078|uniprotkb:O43539|uniprotkb:C0IMW4|uniprotkb:B3KMC1|uniprotkb:B4DFR4|uniprotkb:C0IMW5|uniprotkb:C0IMW7|uniprotkb:H7C3F6|ensembl:ENSP00000323967|ensembl:ENSP00000496094 intact:EBI-358419|uniprotkb:O75784|uniprotkb:O95474|uniprotkb:Q38GA1|uniprotkb:Q76N08|uniprotkb:Q9UBH2|ensembl:ENSP00000479330|ensembl:ENSP00000494049|uniprotkb:Q17S11 psi-mi:smce1_human(display_long)|uniprotkb:BRG1-associated factor 57(gene name synonym)|uniprotkb:SMARCE1(gene name)|psi-mi:SMARCE1(display_short)|uniprotkb:BAF57(gene name synonym) psi-mi:snf5_human(display_long)|uniprotkb:SMARCB1(gene name)|psi-mi:SMARCB1(display_short)|uniprotkb:INI1(gene name synonym)|uniprotkb:SNF5L1(gene name synonym)|uniprotkb:Integrase interactor 1 protein(gene name synonym)|uniprotkb:BAF47(gene name synonym)|uniprotkb:SNF5 homolog(gene name synonym)|uniprotkb:BRG1-associated factor 47(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484885|imex:IM-26985-579 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003070.3|dip:DIP-27614N|dip:DIP-33041N|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR030089|interpro:IPR036910|mint:Q969G3|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:7CYU|reactome:R-HSA-3214858|reactome:R-HSA-8939243|ensembl:ENSG00000073584(gene)|ensembl:ENST00000348513(transcript)|ensembl:ENST00000643683(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex) mint:Q12824|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|rcsb pdb:5AJ1|rcsb pdb:5GJK|rcsb pdb:5L7A|rcsb pdb:5L7B|go:"GO:0007049"(cell cycle)|rcsb pdb:6AX5|go:"GO:0007399"(nervous system development)|rcsb pdb:6KAG|rcsb pdb:6KZ7|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:6UCH|reactome:R-HSA-3214858|go:"GO:0008285"(negative regulation of cell population proliferation)|reactome:R-HSA-8939243|go:"GO:0015074"(DNA integration)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0030154"(cell differentiation)|go:"GO:0030957"(Tat protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035060"(brahma complex)|go:"GO:0039692"(single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0043044"|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex)|go:"GO:0090240"(positive regulation of histone H4 acetylation)|go:"GO:1900110"(negative regulation of histone H3-K9 dimethylation)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902661"(positive regulation of glucose mediated signaling pathway)|go:"GO:2000617"(positive regulation of histone H3-K9 acetylation)|interpro:IPR006939(SNF5/SMARCB1/INI1)|interpro:IPR017393(SWI/SNF chromatin-remodeling complex, component hSNF5/Ini1)|go:"GO:0005730"(nucleolus)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|refseq:NP_001007469.1|refseq:NP_003064.2|ensembl:ENSG00000099956(gene)|ensembl:ENSG00000275837(gene)|ensembl:ENST00000618915(transcript)|ensembl:ENST00000644036(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0001188"(RNA polymerase I preinitiation complex assembly)|go:"GO:0001650"(fibrillar center)|go:"GO:0001741"(XY body)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0002039"(p53 binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-27550N - - comment:"author score: 225" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wf7PrAelShE+8xAwb/UdWKWDkyE9606 rogid:GjUm1RYfDvtNuSNGI6iCWpl8L+I9606 rigid:O4u5PV0aFsoQWduNS+d0Um6pxzU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q969G3 uniprotkb:Q92785 intact:EBI-455078|uniprotkb:O43539|uniprotkb:C0IMW4|uniprotkb:B3KMC1|uniprotkb:B4DFR4|uniprotkb:C0IMW5|uniprotkb:C0IMW7|uniprotkb:H7C3F6|ensembl:ENSP00000323967|ensembl:ENSP00000496094 intact:EBI-359932|intact:EBI-1640314|uniprotkb:A8K7C9|ensembl:ENSP00000436901|uniprotkb:B4DT58 psi-mi:smce1_human(display_long)|uniprotkb:BRG1-associated factor 57(gene name synonym)|uniprotkb:SMARCE1(gene name)|psi-mi:SMARCE1(display_short)|uniprotkb:BAF57(gene name synonym) psi-mi:requ_human(display_long)|uniprotkb:DPF2(gene name)|psi-mi:DPF2(display_short)|uniprotkb:REQ(gene name synonym)|uniprotkb:UBID4(gene name synonym)|uniprotkb:Protein requiem(gene name synonym)|uniprotkb:Apoptosis response zinc finger protein(gene name synonym)|uniprotkb:D4, zinc and double PHD fingers family 2(gene name synonym)|uniprotkb:BAF45D(gene name synonym)|uniprotkb:BRG1-associated factor 45D(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484885|imex:IM-26985-579 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003070.3|dip:DIP-27614N|dip:DIP-33041N|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR030089|interpro:IPR036910|mint:Q969G3|rcsb pdb:6LTH|rcsb pdb:6LTJ|rcsb pdb:7CYU|reactome:R-HSA-3214858|reactome:R-HSA-8939243|ensembl:ENSG00000073584(gene)|ensembl:ENST00000348513(transcript)|ensembl:ENST00000643683(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008080"(N-acetyltransferase activity)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0022008"(neurogenesis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043044"|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0071564"(npBAF complex)|go:"GO:0071565"(nBAF complex) refseq:NP_006259.1|ensembl:ENSG00000133884(gene)|ensembl:ENST00000528416(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006915"(apoptotic process)|go:"GO:0007399"(nervous system development)|go:"GO:0042393"(histone binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0062072"(H3K9me3 modified histone binding)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071565"(nBAF complex)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1905454"(negative regulation of myeloid progenitor cell differentiation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR019787|interpro:IPR025750|interpro:IPR036236|mint:Q92785|rcsb pdb:3IUF|rcsb pdb:5B79|rcsb pdb:5VDC|rcsb pdb:6LTH|rcsb pdb:6LTJ|dip:DIP-27575N - - comment:"author score: 269" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wf7PrAelShE+8xAwb/UdWKWDkyE9606 rogid:Qe2VEvS8nCp6H3FSwm5dZCBibdU9606 rigid:O4u5PV0aFsoQWduNS+d0Um6pxzU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16637 uniprotkb:P62314 intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421 intact:EBI-372177|uniprotkb:P13641|uniprotkb:B5BTZ1|ensembl:ENSP00000300413 psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym) psi-mi:smd1_human(display_long)|uniprotkb:SNRPD1(gene name)|psi-mi:SNRPD1(display_short)|uniprotkb:snRNP core protein D1(gene name synonym)|uniprotkb:Sm-D autoantigen(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484957|imex:IM-26985-209 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N refseq:NP_001278845.1|refseq:NP_008869.1|ensembl:ENSG00000167088(gene)|ensembl:ENST00000300413(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990446"(U1 snRNP binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|go:"GO:0000243"(commitment complex)|interpro:IPR027141|interpro:IPR034102|mint:P62314|rcsb pdb:1B34|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|go:"GO:0000245"(spliceosomal complex assembly)|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5XJL|rcsb pdb:5XJQ|go:"GO:0000387"(spliceosomal snRNP assembly)|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|dip:DIP-31207N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606 rogid:bfXwsV+IOjDPCoOJOoMQgECyiII9606 rigid:3mGe6fz4DABOUAQBcXyJDPCL0W4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16637 uniprotkb:Q2TAM9 intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421 intact:EBI-21564026|ensembl:ENSP00000350716|uniprotkb:A0PJ78|uniprotkb:Q67GI3|uniprotkb:Q86SS1|uniprotkb:Q8TAH8 psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym) psi-mi:tusc1_human(display_long)|uniprotkb:TUSC1(gene name)|psi-mi:TUSC1(display_short)|uniprotkb:TSG-9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484957|imex:IM-26985-209 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N ensembl:ENSG00000198680(gene)|ensembl:ENST00000358022(transcript)|interpro:IPR043450|mint:Q2TAM9|refseq:NP_001004125.1 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606 rogid:Ai3II/t4LWR/+vXzTZCFlNzn1Vc9606 rigid:3mGe6fz4DABOUAQBcXyJDPCL0W4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16637 uniprotkb:Q9UM54 intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421 intact:EBI-350606|uniprotkb:Q5TEM5|uniprotkb:Q5TEM6|uniprotkb:Q5TEM7|uniprotkb:Q9BZZ7|uniprotkb:Q9UEG2|uniprotkb:A6H8V4|uniprotkb:E1P540 psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym) psi-mi:myo6_human(display_long)|uniprotkb:MYO6(gene name)|psi-mi:MYO6(display_short)|uniprotkb:KIAA0389(gene name synonym)|uniprotkb:Unconventional myosin-6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484957|imex:IM-26985-209 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N go:"GO:0051046"(regulation of secretion)|refseq:NP_004990.3|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001726"(ruffle)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030175"(filopodium)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031941"(filamentous actin)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR032412|interpro:IPR036114|interpro:IPR036961|rcsb pdb:2N0Z|rcsb pdb:2N10|rcsb pdb:2N11|go:"GO:0060001"(minus-end directed microfilament motor activity)|rcsb pdb:2N12|rcsb pdb:2N13|rcsb pdb:6E5N|rcsb pdb:6J56|reactome:R-HSA-190873|reactome:R-HSA-399719|reactome:R-HSA-9013418|reactome:R-HSA-9013420|reactome:R-HSA-9013422|refseq:NP_001287828.1|mint:Q9UM54|dip:DIP-33123N - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606 rogid:LYtnU7aRzVE/LDFhZgcK5IvahC09606 rigid:3mGe6fz4DABOUAQBcXyJDPCL0W4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16637 uniprotkb:Q9H840 intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421 intact:EBI-715455|uniprotkb:Q6IA34|ensembl:ENSP00000375813|ensembl:ENSP00000465704|ensembl:ENSP00000466342|ensembl:ENSP00000270257 psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym) psi-mi:gemi7_human(display_long)|uniprotkb:SIP3(gene name synonym)|uniprotkb:GEMIN7(gene name)|psi-mi:GEMIN7(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484957|imex:IM-26985-209 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N refseq:XP_005259319.1|refseq:XP_005259320.1|refseq:NP_001007270.1|refseq:NP_001007271.1|refseq:NP_078983.1|ensembl:ENSG00000142252(gene)|ensembl:ENST00000270257(transcript)|ensembl:ENST00000391951(transcript)|ensembl:ENST00000591607(transcript)|ensembl:ENST00000591747(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0097504"(Gemini of coiled bodies)|go:"GO:0120114"(Sm-like protein family complex)|interpro:IPR020338|interpro:IPR024642|mint:Q9H840|rcsb pdb:1Y96|rcsb pdb:7BBL|reactome:R-HSA-191859|refseq:NP_001305983.1|refseq:NP_001305984.1|refseq:XP_016882801.1|dip:DIP-41750N - - comment:"author score: 53" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606 rogid:jnNKbzuQxiIWKDmv7+je9B5U81Q9606 rigid:3mGe6fz4DABOUAQBcXyJDPCL0W4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16637 uniprotkb:P08621 intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421 intact:EBI-1049228|uniprotkb:P78493|uniprotkb:P78494|uniprotkb:Q15364|uniprotkb:Q15686|uniprotkb:Q15687|uniprotkb:Q15689|uniprotkb:Q99377|uniprotkb:Q9UE45|uniprotkb:Q9UE46|uniprotkb:Q9UE47|uniprotkb:Q9UE48|uniprotkb:Q9UFQ6|intact:EBI-3190943|uniprotkb:B3KUA3|ensembl:ENSP00000472998 psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym) psi-mi:ru17_human(display_long)|uniprotkb:SNRNP70(gene name)|psi-mi:SNRNP70(display_short)|uniprotkb:RPU1(gene name synonym)|uniprotkb:U1AP1(gene name synonym)|uniprotkb:RNPU1Z(gene name synonym)|uniprotkb:SNRP70(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484957|imex:IM-26985-209 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N refseq:NP_003080.2|refseq:NP_001287998.1|ensembl:ENSG00000104852(gene)|ensembl:ENST00000598441(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005685"(U1 snRNP)|go:"GO:0016607"(nuclear speck)|go:"GO:0017069"(snRNA binding)|go:"GO:0030619"(U1 snRNA binding)|go:"GO:0043462"(regulation of ATP-dependent activity)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0061084"(negative regulation of protein refolding)|go:"GO:0071004"(U2-type prespliceosome)|go:"GO:1904715"(negative regulation of chaperone-mediated autophagy)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR022023|interpro:IPR034143|interpro:IPR035979|mint:P08621|rcsb pdb:2L5I|rcsb pdb:2L5J|rcsb pdb:3CW1|rcsb pdb:3PGW|rcsb pdb:4PJO|rcsb pdb:4PKD|rcsb pdb:6QX9|rcsb pdb:7B0Y|reactome:R-HSA-72163|dip:DIP-29406N - - comment:"author score: 68" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606 rogid:/P72B69q5f0TX4vTr4GuRrtgiRM9606 rigid:3mGe6fz4DABOUAQBcXyJDPCL0W4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16637 uniprotkb:P35080 intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421 intact:EBI-473138|uniprotkb:Q8WVF9|uniprotkb:Q9HBK2|uniprotkb:B2R4C8|uniprotkb:Q4VBQ4|uniprotkb:D3DNI4|ensembl:ENSP00000239940 psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym) psi-mi:prof2_human(display_long)|uniprotkb:PFN2(gene name)|psi-mi:PFN2(display_short)|uniprotkb:Profilin II(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484957|imex:IM-26985-209 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N refseq:NP_002619.1|refseq:NP_444252.1|ensembl:ENSG00000070087(gene)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0010633"(negative regulation of epithelial cell migration)|ensembl:ENST00000239940(transcript)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900028"(negative regulation of ruffle assembly)|interpro:IPR005454(Profilin, Mammalian)|interpro:IPR005455(Profilin, plant)|interpro:IPR027310|interpro:IPR029891|interpro:IPR036140|mint:P35080|rcsb pdb:1D1J|reactome:R-HSA-376176|reactome:R-HSA-5663220 - - comment:"author score: 70" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606 rogid:064T9afVEb7WrgJPLVbKByJDUXc9606 rigid:3mGe6fz4DABOUAQBcXyJDPCL0W4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16637 uniprotkb:P62316 intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421 intact:EBI-297993|uniprotkb:P43330|ensembl:ENSP00000342374|ensembl:ENSP00000465216|uniprotkb:A8K797|uniprotkb:J3KPM5 psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym) psi-mi:smd2_human(display_long)|uniprotkb:SNRPD2(gene name)|psi-mi:SNRPD2(display_short)|uniprotkb:snRNP core protein D2(gene name synonym)|uniprotkb:SNRPD1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484957|imex:IM-26985-209 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N ensembl:ENSG00000125743(gene)|ensembl:ENST00000342669(transcript)|ensembl:ENST00000588301(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990446"(U1 snRNP binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027248|mint:P62316|rcsb pdb:1B34|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|refseq:NP_004588.1|refseq:NP_808210.2|dip:DIP-31219N - - comment:"author score: 79" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606 rogid:4OshNPT6N4dOcWMVXrF5Fm8dcnI9606 rigid:3mGe6fz4DABOUAQBcXyJDPCL0W4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16637 uniprotkb:P62304 intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421 intact:EBI-348082|ensembl:ENSP00000400591|uniprotkb:P08578|uniprotkb:Q15498|uniprotkb:Q5BKT2|uniprotkb:B2R5B9 psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym) psi-mi:ruxe_human(display_long)|uniprotkb:SNRPE(gene name)|psi-mi:SNRPE(display_short)|uniprotkb:Sm protein E(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484957|imex:IM-26985-209 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N ensembl:ENSG00000182004(gene)|ensembl:ENST00000414487(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0042633"(hair cycle)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR027078|mint:P62304|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6V4X|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-111367|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-73856|reactome:R-HSA-77588|refseq:NP_003085.1|refseq:NP_001291393.1|refseq:NP_001315566.1|refseq:NP_001315567.1|dip:DIP-31220N - - comment:"author score: 80" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606 rogid:QZ2/v8M+4+8AfWLPYNQO81/IeN09606 rigid:3mGe6fz4DABOUAQBcXyJDPCL0W4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16637 uniprotkb:Q9NWZ8 intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421 intact:EBI-2626001|uniprotkb:C4AMC4|uniprotkb:Q2LJ66|uniprotkb:Q6ZV27|ensembl:ENSP00000369895|ensembl:ENSP00000381398|ensembl:ENSP00000505279|ensembl:ENSP00000505429 psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym) psi-mi:gemi8_human(display_long)|uniprotkb:GEMIN8(gene name)|psi-mi:GEMIN8(display_short)|uniprotkb:FAM51A1(gene name synonym)|uniprotkb:Protein FAM51A1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484957|imex:IM-26985-209 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N refseq:NP_001035944.1|refseq:NP_001035945.1|refseq:NP_060326.1|refseq:XP_016885106.1|refseq:XP_016885107.1|ensembl:ENSG00000046647(gene)|ensembl:ENST00000380523(transcript)|ensembl:ENST00000398355(transcript)|ensembl:ENST00000477386(transcript)|ensembl:ENST00000680255(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR034754|mint:Q9NWZ8|rcsb pdb:7BBL|reactome:R-HSA-191859 - - comment:"author score: 88" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606 rogid:Lvyive5mtL+89HujsYibFUTFP1k9606 rigid:3mGe6fz4DABOUAQBcXyJDPCL0W4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16637 uniprotkb:Q9Y3F4 intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421 intact:EBI-727414|uniprotkb:Q9UQC8|uniprotkb:Q9NTK0|uniprotkb:Q5TZT4|intact:EBI-6190807|uniprotkb:B4DNJ6|uniprotkb:B2R5S5|ensembl:ENSP00000392270 psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym) psi-mi:strap_human(display_long)|uniprotkb:UNR-interacting protein(gene name synonym)|uniprotkb:WD-40 repeat protein PT-WD(gene name synonym)|uniprotkb:MAP activator with WD repeats(gene name synonym)|uniprotkb:STRAP(gene name)|psi-mi:STRAP(display_short)|uniprotkb:MAWD(gene name synonym)|uniprotkb:UNRIP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484957|imex:IM-26985-209 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N refseq:NP_009109.3|ensembl:ENSG00000023734(gene)|ensembl:ENST00000419869(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:1990447"(U2 snRNP binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|mint:Q9Y3F4|reactome:R-HSA-2173788 - - comment:"author score: 101" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606 rogid:/IqZt6BHPxD3S/THUZry4+QUvCE9606 rigid:3mGe6fz4DABOUAQBcXyJDPCL0W4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16637 uniprotkb:P57678 intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421 intact:EBI-356700|uniprotkb:Q9NZS7|uniprotkb:Q9UG32|uniprotkb:Q9Y4Q2|intact:EBI-1058464|ensembl:ENSP00000321706 psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym) psi-mi:gemi4_human(display_long)|uniprotkb:GEMIN4(gene name)|psi-mi:GEMIN4(display_short)|uniprotkb:Component of gems 4(gene name synonym)|uniprotkb:p97(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484957|imex:IM-26985-209 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N refseq:NP_056536.2|ensembl:ENSG00000179409(gene)|ensembl:ENST00000319004(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR033265|mint:P57678|reactome:R-HSA-191859 - - comment:"author score: 108" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606 rogid:PeyFnc2VuUrZrCj8RtkVVS6KQF49606 rigid:3mGe6fz4DABOUAQBcXyJDPCL0W4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16637 uniprotkb:Q9UHI6 intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421 intact:EBI-347658|uniprotkb:Q96F72|uniprotkb:Q9NVM3|uniprotkb:Q9UF59|uniprotkb:Q9UIY0|uniprotkb:Q9Y659|uniprotkb:B4DWV7|ensembl:ENSP00000358716|ensembl:ENSP00000505857 psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym) psi-mi:ddx20_human(display_long)|uniprotkb:DDX20(gene name)|psi-mi:DDX20(display_short)|uniprotkb:DP103(gene name synonym)|uniprotkb:GEMIN3(gene name synonym)|uniprotkb:DEAD box protein 20(gene name synonym)|uniprotkb:DEAD box protein DP 103(gene name synonym)|uniprotkb:Component of gems 3(gene name synonym)|uniprotkb:Gemin-3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484957|imex:IM-26985-209 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N refseq:NP_009135.4|ensembl:ENSP00000358716|ensembl:ENST00000533164|ensembl:ENSP00000434085|ensembl:ENSP00000505857|dip:DIP-32606N|ensembl:ENSG00000064703(gene)|ensembl:ENST00000369702(transcript)|ensembl:ENST00000679724(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006396"(RNA processing)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0048477"(oogenesis)|go:"GO:0050810"(regulation of steroid biosynthetic process)|go:"GO:0090571"(RNA polymerase II transcription repressor complex)|go:"GO:0097504"(Gemini of coiled bodies)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q9UHI6|rcsb pdb:2OXC|rcsb pdb:3B7G|reactome:R-HSA-191859|go:"GO:0043065"(positive regulation of apoptotic process) - - comment:"author score: 130" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606 rogid:Q9IGbhb825yL12imyTlBAHZ4YyU9606 rigid:3mGe6fz4DABOUAQBcXyJDPCL0W4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16637 uniprotkb:Q8WXD5 intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421 intact:EBI-752301|uniprotkb:Q53SI5|uniprotkb:Q8WVB4|uniprotkb:Q9H5G6|uniprotkb:B2RDP8|ensembl:ENSP00000281950 psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym) psi-mi:gemi6_human(display_long)|uniprotkb:SIP2(gene name synonym)|uniprotkb:GEMIN6(gene name)|psi-mi:GEMIN6(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484957|imex:IM-26985-209 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N refseq:NP_079051.9|dip:DIP-41331N|ensembl:ENSG00000152147(gene)|ensembl:ENST00000281950(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016604"(nuclear body)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR009422(Gemin6)|mint:Q8WXD5|rcsb pdb:1Y96|rcsb pdb:7BBL|reactome:R-HSA-191859 - - comment:"author score: 131" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606 rogid:AaQyOsKgOMpkny7dYKmgwu0/c1g9606 rigid:3mGe6fz4DABOUAQBcXyJDPCL0W4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16637 uniprotkb:P62306 intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421 intact:EBI-356900|uniprotkb:A2VCR2|uniprotkb:Q15356|uniprotkb:Q6IBQ1|uniprotkb:Q6P4I0|uniprotkb:B2R498|ensembl:ENSP00000266735 psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym) psi-mi:ruxf_human(display_long)|uniprotkb:SNRPF(gene name)|psi-mi:SNRPF(display_short)|uniprotkb:PBSCF(gene name synonym)|uniprotkb:Sm protein F(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484957|imex:IM-26985-209 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N refseq:NP_003086.1|ensembl:ENSG00000139343(gene)|ensembl:ENST00000266735(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005683"(U7 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|dip:DIP-31221N|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6V4X|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-111367|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-73856|reactome:R-HSA-77588|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR016487(Small nuclear ribonucleoprotein SmF)|interpro:IPR034100|mint:P62306|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC - - comment:"author score: 136" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606 rogid:2RggXu+kFj6wG7gTmxRHOIRvXiM9606 rigid:3mGe6fz4DABOUAQBcXyJDPCL0W4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q16637 uniprotkb:O14893 intact:EBI-395421|uniprotkb:Q13119|uniprotkb:Q549U5|uniprotkb:Q96J51|ensembl:ENSP00000305857|uniprotkb:A8K0V4|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENSP00000370119|ensembl:ENSP00000479920|ensembl:ENSP00000482966|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENSP00000487206|ensembl:ENSP00000487421 intact:EBI-443648|ensembl:ENSP00000250379|ensembl:ENSP00000308533|ensembl:ENSP00000379548|ensembl:ENSP00000416827|uniprotkb:Q2M3B3|uniprotkb:Q9H4F5|uniprotkb:Q9NS77|uniprotkb:Q9NS78|uniprotkb:Q9NS79|uniprotkb:B2R9W8 psi-mi:smn_human(display_long)|uniprotkb:SMN1(gene name)|psi-mi:SMN1(display_short)|uniprotkb:SMN(gene name synonym)|uniprotkb:SMNT(gene name synonym)|uniprotkb:SMN2(gene name)|psi-mi:SMN2(display_short)|uniprotkb:SMNC(gene name synonym)|uniprotkb:Component of gems 1(gene name synonym)|uniprotkb:Gemin-1(gene name synonym) psi-mi:gemi2_human(display_long)|uniprotkb:GEMIN2(gene name)|psi-mi:GEMIN2(display_short)|uniprotkb:SIP1(gene name synonym)|uniprotkb:Component of gems 2(gene name synonym)|uniprotkb:Survival of motor neuron protein-interacting protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25484957|imex:IM-26985-209 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000335.1|refseq:NP_059107.1|refseq:NP_075012.1|refseq:NP_075013.1|refseq:NP_075014.1|refseq:NP_075015.1|ensembl:ENSG00000172062(gene)|ensembl:ENSG00000205571(gene)|ensembl:ENSG00000273772(gene)|ensembl:ENSG00000275349(gene)|ensembl:ENSG00000277773(gene)|ensembl:ENST00000351205(transcript)|ensembl:ENST00000380707(transcript)|ensembl:ENST00000380741(transcript)|ensembl:ENST00000380743(transcript)|ensembl:ENST00000614610(transcript)|ensembl:ENST00000618251(transcript)|ensembl:ENST00000618661(transcript)|ensembl:ENST00000622739(transcript)|ensembl:ENST00000627341(transcript)|ensembl:ENST00000629122(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0007399"(nervous system development)|go:"GO:0015030"(Cajal body)|go:"GO:0016604"(nuclear body)|go:"GO:0030018"(Z disc)|go:"GO:0030424"(axon)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043204"(perikaryon)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR002999(Tudor)|interpro:IPR010304(Survival motor neuron)|mint:Q16637|rcsb pdb:1G5V|rcsb pdb:1MHN|rcsb pdb:2LEH|rcsb pdb:4A4E|rcsb pdb:4A4G|rcsb pdb:4GLI|rcsb pdb:4QQ6|rcsb pdb:5XJL|go:"GO:0034719"(SMN-Sm protein complex)|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|go:"GO:0032797"(SMN complex)|refseq:NP_001284644.1|ensembl:ENSP00000305857|ensembl:ENSP00000370083|ensembl:ENSP00000370117|ensembl:ENST00000380742|ensembl:ENSP00000370118|ensembl:ENSP00000370119|ensembl:ENST00000503079|ensembl:ENSP00000428128|ensembl:ENST00000506163|ensembl:ENSP00000424926|ensembl:ENST00000611442|ensembl:ENSP00000483768|ensembl:ENST00000614240|ensembl:ENSP00000479279|ensembl:ENSP00000479920|ensembl:ENST00000614773|ensembl:ENSP00000481427|ensembl:ENSP00000483515|ensembl:ENSP00000483819|ensembl:ENST00000622158|ensembl:ENSP00000480906|ensembl:ENSP00000482966|ensembl:ENST00000624634|ensembl:ENSP00000485595|ensembl:ENST00000626847|ensembl:ENSP00000486152|ensembl:ENSP00000487421|ensembl:ENST00000628353|ensembl:ENSP00000487029|ensembl:ENST00000628642|ensembl:ENSP00000487015|ensembl:ENSP00000487206|refseq:XP_016865275.1|dip:DIP-31309N ensembl:ENSG00000092208(gene)|ensembl:ENST00000250379(transcript)|ensembl:ENST00000308317(transcript)|ensembl:ENST00000396249(transcript)|ensembl:ENST00000412033(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016604"(nuclear body)|go:"GO:0032797"(SMN complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0097504"(Gemini of coiled bodies)|interpro:IPR017364(Survival of motor neuron protein interacting, gemin2)|interpro:IPR035426|mint:O14893|rcsb pdb:2LEH|rcsb pdb:5XJL|rcsb pdb:5XJQ|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|reactome:R-HSA-191859|refseq:NP_001009182.1|refseq:NP_001009183.1|refseq:NP_003607.1|dip:DIP-32605N - - comment:"author score: 173" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QGivm7E8suciCWXO4l0zCUzCl2g9606 rogid:cCbpiHhHdfq+SNoIud5xipHgYVA9606 rigid:3mGe6fz4DABOUAQBcXyJDPCL0W4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NB12 uniprotkb:P68363 intact:EBI-8463848|uniprotkb:A6NE13|intact:UNK-5851610|uniprotkb:A0AV30|ensembl:ENSP00000393453 intact:EBI-487083|intact:EBI-1384226|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:Q27I68|ensembl:ENSP00000336799|uniprotkb:Q8WU19 psi-mi:smyd1_human(display_long)|uniprotkb:SET and MYND domain-containing protein 1(gene name synonym)|uniprotkb:SMYD1(gene name)|psi-mi:SMYD1(display_short) psi-mi:tba1b_human(display_long)|uniprotkb:TUBA1B(gene name)|psi-mi:TUBA1B(display_short)|uniprotkb:Tubulin alpha-ubiquitous chain(gene name synonym)|uniprotkb:Alpha-tubulin ubiquitous(gene name synonym)|uniprotkb:Tubulin K-alpha-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485008|imex:IM-26985-211 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_938015.1|ensembl:ENSG00000115593(gene)|ensembl:ENST00000419482(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007507"(heart development)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR044418|mint:Q8NB12 refseq:NP_006073.2|ensembl:ENSG00000123416(gene)|ensembl:ENST00000336023(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-983189|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|go:"GO:0045121"(membrane raft)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68363|rcsb pdb:2E4H|rcsb pdb:5IJ0|rcsb pdb:5IJ9|rcsb pdb:5N5N|rcsb pdb:6E7B|rcsb pdb:6E7C|rcsb pdb:6I2I|go:"GO:0051301"(cell division)|rcsb pdb:6J4V|rcsb pdb:6J8O|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|rcsb pdb:6S8L|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9013407|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-2132295|reactome:R-HSA-9668328 - function:Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis|comment:mint|comment:homomint comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5RdKKV9b/b21FxoCK+LJbnyxVw09606 rogid:D4YpuLCXl/S+53qV7P7sF81aARY9606 rigid:p311XKGLKWxao2AMjnoeb0VDLiU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NB12 uniprotkb:P04632 intact:EBI-8463848|uniprotkb:A6NE13|intact:UNK-5851610|uniprotkb:A0AV30|ensembl:ENSP00000393453 intact:EBI-711828|uniprotkb:Q8WTX3|uniprotkb:Q96EW0|uniprotkb:A8K0P1|ensembl:ENSP00000246533|ensembl:ENSP00000464849 psi-mi:smyd1_human(display_long)|uniprotkb:SET and MYND domain-containing protein 1(gene name synonym)|uniprotkb:SMYD1(gene name)|psi-mi:SMYD1(display_short) psi-mi:cpns1_human(display_long)|uniprotkb:Calcium-dependent protease small subunit 1(gene name synonym)|uniprotkb:Calcium-dependent protease small subunit(gene name synonym)|uniprotkb:Calpain regulatory subunit(gene name synonym)|uniprotkb:Calcium-activated neutral proteinase small subunit(gene name synonym)|uniprotkb:CAPNS1(gene name)|psi-mi:CAPNS1(display_short)|uniprotkb:CAPN4(gene name synonym)|uniprotkb:CAPNS(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485008|imex:IM-26985-211 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_938015.1|ensembl:ENSG00000115593(gene)|ensembl:ENST00000419482(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007507"(heart development)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR044418|mint:Q8NB12 ensembl:ENSG00000126247(gene)|ensembl:ENST00000246533(transcript)|ensembl:ENST00000588815(transcript)|go:"GO:0004198"(calcium-dependent cysteine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR029642|mint:P04632|rcsb pdb:1KFU|rcsb pdb:1KFX|rcsb pdb:4PHJ|rcsb pdb:4PHK|rcsb pdb:4PHM|rcsb pdb:4WQ2|rcsb pdb:4WQ3|rcsb pdb:5D69|rcsb pdb:6QLB|reactome:R-HSA-1474228|reactome:R-HSA-6809371|reactome:R-HSA-8862803|refseq:NP_001003962.1|refseq:NP_001740.1|refseq:NP_001289561.1|refseq:NP_001289562.1|refseq:XP_005259352.1|refseq:XP_005259353.1 - function:Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis|comment:mint|comment:homomint comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5RdKKV9b/b21FxoCK+LJbnyxVw09606 rogid:siQugDvaWq0YjOr8qOCf0BsRRKs9606 rigid:p311XKGLKWxao2AMjnoeb0VDLiU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NB12 uniprotkb:Q5T1J5 intact:EBI-8463848|uniprotkb:A6NE13|intact:UNK-5851610|uniprotkb:A0AV30|ensembl:ENSP00000393453 intact:EBI-5325274 psi-mi:smyd1_human(display_long)|uniprotkb:SET and MYND domain-containing protein 1(gene name synonym)|uniprotkb:SMYD1(gene name)|psi-mi:SMYD1(display_short) psi-mi:chch9_human(display_long)|uniprotkb:CHCHD2P9(gene name)|psi-mi:CHCHD2P9(display_short)|uniprotkb:C9orf49(gene name synonym)|uniprotkb:CHCHD9(gene name synonym)|uniprotkb:Coiled-coil-helix-coiled-coil-helix domain-containing 2 pseudogene 9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485008|imex:IM-26985-211 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_938015.1|ensembl:ENSG00000115593(gene)|ensembl:ENST00000419482(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007507"(heart development)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR044418|mint:Q8NB12 go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|mint:Q5T1J5 - function:Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis|comment:mint|comment:homomint comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5RdKKV9b/b21FxoCK+LJbnyxVw09606 rogid:nxLtnxxMIGeGK2oC3BIhcwkacSs9606 rigid:p311XKGLKWxao2AMjnoeb0VDLiU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NB12 uniprotkb:Q13185 intact:EBI-8463848|uniprotkb:A6NE13|intact:UNK-5851610|uniprotkb:A0AV30|ensembl:ENSP00000393453 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 psi-mi:smyd1_human(display_long)|uniprotkb:SET and MYND domain-containing protein 1(gene name synonym)|uniprotkb:SMYD1(gene name)|psi-mi:SMYD1(display_short) psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485008|imex:IM-26985-211 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_938015.1|ensembl:ENSG00000115593(gene)|ensembl:ENST00000419482(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007507"(heart development)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR044418|mint:Q8NB12 go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N - function:Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis|comment:mint|comment:homomint comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5RdKKV9b/b21FxoCK+LJbnyxVw09606 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rigid:p311XKGLKWxao2AMjnoeb0VDLiU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NB12 uniprotkb:P82979 intact:EBI-8463848|uniprotkb:A6NE13|intact:UNK-5851610|uniprotkb:A0AV30|ensembl:ENSP00000393453 intact:EBI-347495|uniprotkb:Q9P066|uniprotkb:A8K393|ensembl:ENSP00000337632|ensembl:ENSP00000449409 psi-mi:smyd1_human(display_long)|uniprotkb:SET and MYND domain-containing protein 1(gene name synonym)|uniprotkb:SMYD1(gene name)|psi-mi:SMYD1(display_short) psi-mi:sarnp_human(display_long)|uniprotkb:HSPC316(orf name)|uniprotkb:Cytokine-induced protein of 29 kDa(gene name synonym)|uniprotkb:SARNP(gene name)|psi-mi:SARNP(display_short)|uniprotkb:Proliferation-associated cytokine-inducible protein CIP29(gene name synonym)|uniprotkb:HCC1(gene name synonym)|uniprotkb:Nuclear protein Hcc-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485008|imex:IM-26985-211 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_938015.1|ensembl:ENSG00000115593(gene)|ensembl:ENST00000419482(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007507"(heart development)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR044418|mint:Q8NB12 refseq:NP_149073.1|ensembl:ENSG00000205323(gene)|ensembl:ENST00000336133(transcript)|ensembl:ENST00000546604(transcript)|go:"GO:0000346"(transcription export complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006417"(regulation of translation)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|interpro:IPR036361|mint:P82979|rcsb pdb:2DO1|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856|interpro:IPR003034(DNA-binding SAP) - function:Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis|comment:mint|comment:homomint comment:"author score: 39" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5RdKKV9b/b21FxoCK+LJbnyxVw09606 rogid:O/j7XYd9K3eQu1JS58FSsEyPRpE9606 rigid:p311XKGLKWxao2AMjnoeb0VDLiU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NB12 uniprotkb:P30520 intact:EBI-8463848|uniprotkb:A6NE13|intact:UNK-5851610|uniprotkb:A0AV30|ensembl:ENSP00000393453 intact:EBI-1042898|uniprotkb:Q96EG7|ensembl:ENSP00000355493|uniprotkb:B1AQM5 psi-mi:smyd1_human(display_long)|uniprotkb:SET and MYND domain-containing protein 1(gene name synonym)|uniprotkb:SMYD1(gene name)|psi-mi:SMYD1(display_short) psi-mi:pura2_human(display_long)|uniprotkb:ADSS2(gene name)|psi-mi:ADSS2(display_short)|uniprotkb:ADSS(gene name synonym)|uniprotkb:Adenylosuccinate synthetase, acidic isozyme(gene name synonym)|uniprotkb:Adenylosuccinate synthetase, liver isozyme(gene name synonym)|uniprotkb:IMP--aspartate ligase 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485008|imex:IM-26985-211 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_938015.1|ensembl:ENSG00000115593(gene)|ensembl:ENST00000419482(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007507"(heart development)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR044418|mint:Q8NB12 ensembl:ENSG00000035687(gene)|ensembl:ENST00000366535(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002376"(immune system process)|go:"GO:0004019"(adenylosuccinate synthase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006167"(AMP biosynthetic process)|go:"GO:0006531"(aspartate metabolic process)|go:"GO:0014074"(response to purine-containing compound)|go:"GO:0042301"(phosphate ion binding)|go:"GO:0044208"('de novo' AMP biosynthetic process)|go:"GO:0046040"(IMP metabolic process)|go:"GO:0060359"(response to ammonium ion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071257"(cellular response to electrical stimulus)|interpro:IPR001114(Adenylosuccinate synthetase)|interpro:IPR018220|interpro:IPR027417|interpro:IPR027529|interpro:IPR033128|interpro:IPR042109|interpro:IPR042110|interpro:IPR042111|mint:P30520|rcsb pdb:2V40|reactome:R-HSA-73817|refseq:NP_001117.2 - function:Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis|comment:mint|comment:homomint comment:"author score: 45" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5RdKKV9b/b21FxoCK+LJbnyxVw09606 rogid:Tyydt3Z/JHGYtfY9oc9XfFkDguM9606 rigid:p311XKGLKWxao2AMjnoeb0VDLiU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P00441 uniprotkb:P62258 intact:EBI-990792|uniprotkb:A6NHJ0|uniprotkb:Q16669|uniprotkb:Q16711|uniprotkb:Q16838|uniprotkb:Q16839|uniprotkb:Q16840|uniprotkb:Q6NR85|ensembl:ENSP00000270142|uniprotkb:D3DSE4 intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335|ensembl:ENSP00000487356 psi-mi:sodc_human(display_long)|uniprotkb:Superoxide dismutase 1(gene name synonym)|uniprotkb:SOD1(gene name)|psi-mi:SOD1(display_short) psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485203|imex:IM-26985-137 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000142168(gene)|ensembl:ENST00000270142(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000303"(response to superoxide)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001890"(placenta development)|go:"GO:0001895"(retina homeostasis)|go:"GO:0002262"(myeloid cell homeostasis)|go:"GO:0004784"(superoxide dismutase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005764"(lysosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007566"(embryo implantation)|go:"GO:0007569"(cell aging)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0001975"(response to amphetamine)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033081"(regulation of T cell differentiation in thymus)|go:"GO:0034465"(response to carbon monoxide)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009408"(response to heat)|go:"GO:0010033"(response to organic substance)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0031045"(dense core granule)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031667"(response to nutrient levels)|interpro:IPR024134|interpro:IPR036423|mint:P00441|rcsb pdb:1AZV|rcsb pdb:1BA9|rcsb pdb:1DSW|rcsb pdb:1FUN|rcsb pdb:1HL4|rcsb pdb:1HL5|rcsb pdb:1KMG|rcsb pdb:1L3N|rcsb pdb:1MFM|rcsb pdb:1N18|rcsb pdb:1N19|interpro:IPR018152|rcsb pdb:1OEZ|rcsb pdb:1OZT|rcsb pdb:1OZU|rcsb pdb:1P1V|rcsb pdb:1PTZ|rcsb pdb:1PU0|rcsb pdb:1RK7|rcsb pdb:1SOS|rcsb pdb:1SPD|rcsb pdb:1UXL|rcsb pdb:1UXM|rcsb pdb:2AF2|rcsb pdb:2C9S|rcsb pdb:2C9U|rcsb pdb:2C9V|rcsb pdb:2GBT|rcsb pdb:2GBU|rcsb pdb:2GBV|rcsb pdb:2LU5|rcsb pdb:2MP3|rcsb pdb:2NAM|rcsb pdb:2NNX|rcsb pdb:2R27|rcsb pdb:2V0A|rcsb pdb:2VR6|rcsb pdb:2VR7|rcsb pdb:2VR8|rcsb pdb:2WKO|rcsb pdb:2WYT|rcsb pdb:2WYZ|rcsb pdb:2WZ0|rcsb pdb:2WZ5|rcsb pdb:2WZ6|rcsb pdb:2XJK|rcsb pdb:2XJL|rcsb pdb:2ZKW|rcsb pdb:2ZKX|rcsb pdb:2ZKY|rcsb pdb:3CQP|rcsb pdb:3CQQ|rcsb pdb:3ECU|rcsb pdb:3ECV|rcsb pdb:3ECW|rcsb pdb:3GQF|rcsb pdb:3GTV|rcsb pdb:3GZO|rcsb pdb:3GZP|rcsb pdb:3GZQ|rcsb pdb:3H2P|rcsb pdb:3H2Q|rcsb pdb:3HFF|rcsb pdb:3K91|rcsb pdb:3KH3|rcsb pdb:3KH4|rcsb pdb:3LTV|rcsb pdb:3QQD|rcsb pdb:3RE0|rcsb pdb:3T5W|rcsb pdb:4A7G|rcsb pdb:4A7Q|rcsb pdb:4A7S|rcsb pdb:4A7T|rcsb pdb:4A7U|rcsb pdb:4A7V|rcsb pdb:4B3E|rcsb pdb:4BCY|rcsb pdb:4BCZ|rcsb pdb:4BD4|rcsb pdb:4FF9|rcsb pdb:4MCM|rcsb pdb:4MCN|rcsb pdb:4NIN|rcsb pdb:4NIO|rcsb pdb:4NIP|rcsb pdb:4OH2|rcsb pdb:4SOD|rcsb pdb:4XCR|rcsb pdb:5DLI|rcsb pdb:5IIW|rcsb pdb:5J07|rcsb pdb:5J0C|rcsb pdb:5J0F|rcsb pdb:5J0G|rcsb pdb:5K02|rcsb pdb:5O3Y|rcsb pdb:5O40|rcsb pdb:5U9M|rcsb pdb:5WOR|rcsb pdb:5YTO|rcsb pdb:5YTU|rcsb pdb:5YUL|rcsb pdb:6A9O|rcsb pdb:6B79|rcsb pdb:6DTK|rcsb pdb:6FFK|rcsb pdb:6FLH|rcsb pdb:6FOI|rcsb pdb:6FOL|rcsb pdb:6FON|rcsb pdb:6FP6|rcsb pdb:6SPA|rcsb pdb:6SPH|rcsb pdb:6SPI|rcsb pdb:6SPJ|rcsb pdb:6SPK|rcsb pdb:6Z3V|rcsb pdb:6Z4G|rcsb pdb:6Z4H|rcsb pdb:6Z4I|rcsb pdb:6Z4J|rcsb pdb:6Z4K|rcsb pdb:6Z4L|rcsb pdb:6Z4M|rcsb pdb:6Z4O|reactome:R-HSA-114608|reactome:R-HSA-3299685|reactome:R-HSA-8950505|rcsb pdb:5WMJ|go:"GO:0046688"(response to copper ion)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048538"(thymus development)|go:"GO:0048678"(response to axon injury)|go:"GO:0050665"(hydrogen peroxide biosynthetic process)|go:"GO:0046677"(response to antibiotic)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051087"(chaperone binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060047"(heart contraction)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0060087"(relaxation of vascular associated smooth muscle)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097332"(response to antipsychotic drug)|go:"GO:1902177"(positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001424(Superoxide dismutase, copper/zinc binding)|refseq:NP_000445.1|dip:DIP-44941N refseq:NP_006752.1|dip:DIP-36676N|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|ensembl:ENSG00000108953(gene)|ensembl:ENSG00000274474(gene)|ensembl:ENST00000264335(transcript)|ensembl:ENST00000627231(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003064"(regulation of heart rate by hormone)|go:"GO:0003723"(RNA binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|reactome:R-HSA-111447 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W5O3CdnrxKm1kudXW04wxnCxTY09606 rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606 rigid:nxZdeyqipEiEzelbB2B5UTkBIM8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P00441 uniprotkb:O14618 intact:EBI-990792|uniprotkb:A6NHJ0|uniprotkb:Q16669|uniprotkb:Q16711|uniprotkb:Q16838|uniprotkb:Q16839|uniprotkb:Q16840|uniprotkb:Q6NR85|ensembl:ENSP00000270142|uniprotkb:D3DSE4 intact:EBI-11668690|uniprotkb:Q2M366|uniprotkb:Q8NEV0|ensembl:ENSP00000436318 psi-mi:sodc_human(display_long)|uniprotkb:Superoxide dismutase 1(gene name synonym)|uniprotkb:SOD1(gene name)|psi-mi:SOD1(display_short) psi-mi:ccs_human(display_long)|uniprotkb:CCS(gene name)|psi-mi:CCS(display_short)|uniprotkb:Superoxide dismutase copper chaperone(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485203|imex:IM-26985-137 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000142168(gene)|ensembl:ENST00000270142(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000303"(response to superoxide)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001890"(placenta development)|go:"GO:0001895"(retina homeostasis)|go:"GO:0002262"(myeloid cell homeostasis)|go:"GO:0004784"(superoxide dismutase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005764"(lysosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007566"(embryo implantation)|go:"GO:0007569"(cell aging)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0001975"(response to amphetamine)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033081"(regulation of T cell differentiation in thymus)|go:"GO:0034465"(response to carbon monoxide)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009408"(response to heat)|go:"GO:0010033"(response to organic substance)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0031045"(dense core granule)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031667"(response to nutrient levels)|interpro:IPR024134|interpro:IPR036423|mint:P00441|rcsb pdb:1AZV|rcsb pdb:1BA9|rcsb pdb:1DSW|rcsb pdb:1FUN|rcsb pdb:1HL4|rcsb pdb:1HL5|rcsb pdb:1KMG|rcsb pdb:1L3N|rcsb pdb:1MFM|rcsb pdb:1N18|rcsb pdb:1N19|interpro:IPR018152|rcsb pdb:1OEZ|rcsb pdb:1OZT|rcsb pdb:1OZU|rcsb pdb:1P1V|rcsb pdb:1PTZ|rcsb pdb:1PU0|rcsb pdb:1RK7|rcsb pdb:1SOS|rcsb pdb:1SPD|rcsb pdb:1UXL|rcsb pdb:1UXM|rcsb pdb:2AF2|rcsb pdb:2C9S|rcsb pdb:2C9U|rcsb pdb:2C9V|rcsb pdb:2GBT|rcsb pdb:2GBU|rcsb pdb:2GBV|rcsb pdb:2LU5|rcsb pdb:2MP3|rcsb pdb:2NAM|rcsb pdb:2NNX|rcsb pdb:2R27|rcsb pdb:2V0A|rcsb pdb:2VR6|rcsb pdb:2VR7|rcsb pdb:2VR8|rcsb pdb:2WKO|rcsb pdb:2WYT|rcsb pdb:2WYZ|rcsb pdb:2WZ0|rcsb pdb:2WZ5|rcsb pdb:2WZ6|rcsb pdb:2XJK|rcsb pdb:2XJL|rcsb pdb:2ZKW|rcsb pdb:2ZKX|rcsb pdb:2ZKY|rcsb pdb:3CQP|rcsb pdb:3CQQ|rcsb pdb:3ECU|rcsb pdb:3ECV|rcsb pdb:3ECW|rcsb pdb:3GQF|rcsb pdb:3GTV|rcsb pdb:3GZO|rcsb pdb:3GZP|rcsb pdb:3GZQ|rcsb pdb:3H2P|rcsb pdb:3H2Q|rcsb pdb:3HFF|rcsb pdb:3K91|rcsb pdb:3KH3|rcsb pdb:3KH4|rcsb pdb:3LTV|rcsb pdb:3QQD|rcsb pdb:3RE0|rcsb pdb:3T5W|rcsb pdb:4A7G|rcsb pdb:4A7Q|rcsb pdb:4A7S|rcsb pdb:4A7T|rcsb pdb:4A7U|rcsb pdb:4A7V|rcsb pdb:4B3E|rcsb pdb:4BCY|rcsb pdb:4BCZ|rcsb pdb:4BD4|rcsb pdb:4FF9|rcsb pdb:4MCM|rcsb pdb:4MCN|rcsb pdb:4NIN|rcsb pdb:4NIO|rcsb pdb:4NIP|rcsb pdb:4OH2|rcsb pdb:4SOD|rcsb pdb:4XCR|rcsb pdb:5DLI|rcsb pdb:5IIW|rcsb pdb:5J07|rcsb pdb:5J0C|rcsb pdb:5J0F|rcsb pdb:5J0G|rcsb pdb:5K02|rcsb pdb:5O3Y|rcsb pdb:5O40|rcsb pdb:5U9M|rcsb pdb:5WOR|rcsb pdb:5YTO|rcsb pdb:5YTU|rcsb pdb:5YUL|rcsb pdb:6A9O|rcsb pdb:6B79|rcsb pdb:6DTK|rcsb pdb:6FFK|rcsb pdb:6FLH|rcsb pdb:6FOI|rcsb pdb:6FOL|rcsb pdb:6FON|rcsb pdb:6FP6|rcsb pdb:6SPA|rcsb pdb:6SPH|rcsb pdb:6SPI|rcsb pdb:6SPJ|rcsb pdb:6SPK|rcsb pdb:6Z3V|rcsb pdb:6Z4G|rcsb pdb:6Z4H|rcsb pdb:6Z4I|rcsb pdb:6Z4J|rcsb pdb:6Z4K|rcsb pdb:6Z4L|rcsb pdb:6Z4M|rcsb pdb:6Z4O|reactome:R-HSA-114608|reactome:R-HSA-3299685|reactome:R-HSA-8950505|rcsb pdb:5WMJ|go:"GO:0046688"(response to copper ion)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048538"(thymus development)|go:"GO:0048678"(response to axon injury)|go:"GO:0050665"(hydrogen peroxide biosynthetic process)|go:"GO:0046677"(response to antibiotic)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051087"(chaperone binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060047"(heart contraction)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0060087"(relaxation of vascular associated smooth muscle)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097332"(response to antipsychotic drug)|go:"GO:1902177"(positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001424(Superoxide dismutase, copper/zinc binding)|refseq:NP_000445.1|dip:DIP-44941N refseq:NP_005116.1|ensembl:ENSG00000173992(gene)|ensembl:ENST00000533244(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015680"(protein maturation by copper ion transfer)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0045296"(cadherin binding)|go:"GO:0051353"(positive regulation of oxidoreductase activity)|interpro:IPR001424(Superoxide dismutase, copper/zinc binding)|interpro:IPR006121(Heavy metal transport/detoxification protein)|interpro:IPR018152|interpro:IPR024134|interpro:IPR036163|interpro:IPR036423|mint:O14618|rcsb pdb:1DO5|rcsb pdb:2CRL|rcsb pdb:2RSQ|rcsb pdb:6FN8|rcsb pdb:6FOL|rcsb pdb:6FON|rcsb pdb:6FP6|reactome:R-HSA-3299685 - - comment:"author score: 35" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:W5O3CdnrxKm1kudXW04wxnCxTY09606 rogid:r5pGUXbIewnEFuTqrKn78aG7N309606 rigid:nxZdeyqipEiEzelbB2B5UTkBIM8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H7B4 uniprotkb:Q8NB12 intact:EBI-347919|ensembl:ENSP00000419184|uniprotkb:Q86TL8|uniprotkb:Q8N5Z6|uniprotkb:Q96AI5|uniprotkb:B1AN38|uniprotkb:A8K0P0 intact:EBI-8463848|uniprotkb:A6NE13|intact:UNK-5851610|uniprotkb:A0AV30|ensembl:ENSP00000393453 psi-mi:smyd3_human(display_long)|uniprotkb:SMYD3(gene name)|psi-mi:SMYD3(display_short)|uniprotkb:ZMYND1(gene name synonym)|uniprotkb:ZNFN3A1(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 1(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 3(gene name synonym) psi-mi:smyd1_human(display_long)|uniprotkb:SET and MYND domain-containing protein 1(gene name synonym)|uniprotkb:SMYD1(gene name)|psi-mi:SMYD1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485113|imex:IM-26985-365 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000185420(gene)|ensembl:ENST00000490107(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0014904"(myotube cell development)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR025805|interpro:IPR044420|mint:Q9H7B4|rcsb pdb:3MEK|rcsb pdb:3OXF|rcsb pdb:3OXG|rcsb pdb:3OXL|rcsb pdb:3PDN|rcsb pdb:3QWP|rcsb pdb:3RU0|rcsb pdb:5CCL|rcsb pdb:5CCM|rcsb pdb:5EX0|rcsb pdb:5EX3|rcsb pdb:5HI7|rcsb pdb:5HQ8|rcsb pdb:5V37|rcsb pdb:5XXG|rcsb pdb:5XXJ|rcsb pdb:5YJO|rcsb pdb:6IJL|rcsb pdb:6O9O|rcsb pdb:6P6G|rcsb pdb:6P6K|rcsb pdb:5XXD|rcsb pdb:6P7Z|rcsb pdb:6PAF|rcsb pdb:6YUH|rcsb pdb:7BJ1|reactome:R-HSA-3214841|refseq:XP_011542559.1|refseq:NP_001161212.1|refseq:NP_073580.1|dip:DIP-32653N refseq:NP_938015.1|ensembl:ENSG00000115593(gene)|ensembl:ENST00000419482(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007507"(heart development)|go:"GO:0010831"(positive regulation of myotube differentiation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR044418|mint:Q8NB12 - - function:Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis|comment:mint|comment:homomint|comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:gKISZLHkhKTIVn2O646c4OQhLzc9606 rogid:5RdKKV9b/b21FxoCK+LJbnyxVw09606 rigid:FXV/vHBYbS4EPkWWP/nXFK9Y1wo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H7B4 uniprotkb:P62424 intact:EBI-347919|ensembl:ENSP00000419184|uniprotkb:Q86TL8|uniprotkb:Q8N5Z6|uniprotkb:Q96AI5|uniprotkb:B1AN38|uniprotkb:A8K0P0 intact:EBI-354172|uniprotkb:P11518|uniprotkb:Q5T8U4|ensembl:ENSP00000361076|ensembl:ENSP00000487443 psi-mi:smyd3_human(display_long)|uniprotkb:SMYD3(gene name)|psi-mi:SMYD3(display_short)|uniprotkb:ZMYND1(gene name synonym)|uniprotkb:ZNFN3A1(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 1(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 3(gene name synonym) psi-mi:rl7a_human(display_long)|uniprotkb:RPL7A(gene name)|psi-mi:RPL7A(display_short)|uniprotkb:SURF-3(gene name synonym)|uniprotkb:SURF3(gene name synonym)|uniprotkb:Surfeit locus protein 3(gene name synonym)|uniprotkb:PLA-X polypeptide(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485113|imex:IM-26985-365 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000185420(gene)|ensembl:ENST00000490107(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0014904"(myotube cell development)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR025805|interpro:IPR044420|mint:Q9H7B4|rcsb pdb:3MEK|rcsb pdb:3OXF|rcsb pdb:3OXG|rcsb pdb:3OXL|rcsb pdb:3PDN|rcsb pdb:3QWP|rcsb pdb:3RU0|rcsb pdb:5CCL|rcsb pdb:5CCM|rcsb pdb:5EX0|rcsb pdb:5EX3|rcsb pdb:5HI7|rcsb pdb:5HQ8|rcsb pdb:5V37|rcsb pdb:5XXG|rcsb pdb:5XXJ|rcsb pdb:5YJO|rcsb pdb:6IJL|rcsb pdb:6O9O|rcsb pdb:6P6G|rcsb pdb:6P6K|rcsb pdb:5XXD|rcsb pdb:6P7Z|rcsb pdb:6PAF|rcsb pdb:6YUH|rcsb pdb:7BJ1|reactome:R-HSA-3214841|refseq:XP_011542559.1|refseq:NP_001161212.1|refseq:NP_073580.1|dip:DIP-32653N refseq:NP_000963.1|dip:DIP-31502N|ensembl:ENSG00000148303(gene)|ensembl:ENSG00000280858(gene)|ensembl:ENST00000323345(transcript)|ensembl:ENST00000630979(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR001921(Ribosomal protein L7A)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|mint:P62424|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|go:"GO:0005634"(nucleus)|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:gKISZLHkhKTIVn2O646c4OQhLzc9606 rogid:shPtLmc+oabT/rSwho+tP1iJy4k9606 rigid:FXV/vHBYbS4EPkWWP/nXFK9Y1wo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H7B4 uniprotkb:P62805 intact:EBI-347919|ensembl:ENSP00000419184|uniprotkb:Q86TL8|uniprotkb:Q8N5Z6|uniprotkb:Q96AI5|uniprotkb:B1AN38|uniprotkb:A8K0P0 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:smyd3_human(display_long)|uniprotkb:SMYD3(gene name)|psi-mi:SMYD3(display_short)|uniprotkb:ZMYND1(gene name synonym)|uniprotkb:ZNFN3A1(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 1(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 3(gene name synonym) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485113|imex:IM-26985-365 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000185420(gene)|ensembl:ENST00000490107(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0014904"(myotube cell development)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR025805|interpro:IPR044420|mint:Q9H7B4|rcsb pdb:3MEK|rcsb pdb:3OXF|rcsb pdb:3OXG|rcsb pdb:3OXL|rcsb pdb:3PDN|rcsb pdb:3QWP|rcsb pdb:3RU0|rcsb pdb:5CCL|rcsb pdb:5CCM|rcsb pdb:5EX0|rcsb pdb:5EX3|rcsb pdb:5HI7|rcsb pdb:5HQ8|rcsb pdb:5V37|rcsb pdb:5XXG|rcsb pdb:5XXJ|rcsb pdb:5YJO|rcsb pdb:6IJL|rcsb pdb:6O9O|rcsb pdb:6P6G|rcsb pdb:6P6K|rcsb pdb:5XXD|rcsb pdb:6P7Z|rcsb pdb:6PAF|rcsb pdb:6YUH|rcsb pdb:7BJ1|reactome:R-HSA-3214841|refseq:XP_011542559.1|refseq:NP_001161212.1|refseq:NP_073580.1|dip:DIP-32653N ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:gKISZLHkhKTIVn2O646c4OQhLzc9606 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 rigid:FXV/vHBYbS4EPkWWP/nXFK9Y1wo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H7B4 uniprotkb:Q71UM5 intact:EBI-347919|ensembl:ENSP00000419184|uniprotkb:Q86TL8|uniprotkb:Q8N5Z6|uniprotkb:Q96AI5|uniprotkb:B1AN38|uniprotkb:A8K0P0 intact:EBI-355126|uniprotkb:Q9BTJ1|ensembl:ENSP00000331019 psi-mi:smyd3_human(display_long)|uniprotkb:SMYD3(gene name)|psi-mi:SMYD3(display_short)|uniprotkb:ZMYND1(gene name synonym)|uniprotkb:ZNFN3A1(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 1(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 3(gene name synonym) psi-mi:rs27l_human(display_long)|uniprotkb:RPS27L(gene name)|psi-mi:RPS27L(display_short)|uniprotkb:Small ribosomal subunit protein eS27-like(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485113|imex:IM-26985-365 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000185420(gene)|ensembl:ENST00000490107(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0014904"(myotube cell development)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR025805|interpro:IPR044420|mint:Q9H7B4|rcsb pdb:3MEK|rcsb pdb:3OXF|rcsb pdb:3OXG|rcsb pdb:3OXL|rcsb pdb:3PDN|rcsb pdb:3QWP|rcsb pdb:3RU0|rcsb pdb:5CCL|rcsb pdb:5CCM|rcsb pdb:5EX0|rcsb pdb:5EX3|rcsb pdb:5HI7|rcsb pdb:5HQ8|rcsb pdb:5V37|rcsb pdb:5XXG|rcsb pdb:5XXJ|rcsb pdb:5YJO|rcsb pdb:6IJL|rcsb pdb:6O9O|rcsb pdb:6P6G|rcsb pdb:6P6K|rcsb pdb:5XXD|rcsb pdb:6P7Z|rcsb pdb:6PAF|rcsb pdb:6YUH|rcsb pdb:7BJ1|reactome:R-HSA-3214841|refseq:XP_011542559.1|refseq:NP_001161212.1|refseq:NP_073580.1|dip:DIP-32653N refseq:NP_057004.1|ensembl:ENSG00000185088(gene)|ensembl:ENST00000330964(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0006412"(translation)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008494"(translation activator activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046872"(metal ion binding)|interpro:IPR000592(Ribosomal protein S27e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR023407|mint:Q71UM5|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:gKISZLHkhKTIVn2O646c4OQhLzc9606 rogid:OVIAlDF6dN3DxLZgQFrFl8r0Z0I9606 rigid:FXV/vHBYbS4EPkWWP/nXFK9Y1wo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H7B4 uniprotkb:P05387 intact:EBI-347919|ensembl:ENSP00000419184|uniprotkb:Q86TL8|uniprotkb:Q8N5Z6|uniprotkb:Q96AI5|uniprotkb:B1AN38|uniprotkb:A8K0P0 intact:EBI-352813|ensembl:ENSP00000322419|ensembl:ENSP00000431240|uniprotkb:Q6FG96 psi-mi:smyd3_human(display_long)|uniprotkb:SMYD3(gene name)|psi-mi:SMYD3(display_short)|uniprotkb:ZMYND1(gene name synonym)|uniprotkb:ZNFN3A1(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 1(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 3(gene name synonym) psi-mi:rla2_human(display_long)|uniprotkb:RPLP2(gene name)|psi-mi:RPLP2(display_short)|uniprotkb:RPP2(gene name synonym)|uniprotkb:D11S2243E(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-44(gene name synonym)|uniprotkb:Large ribosomal subunit protein P2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485113|imex:IM-26985-365 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000185420(gene)|ensembl:ENST00000490107(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0014904"(myotube cell development)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR025805|interpro:IPR044420|mint:Q9H7B4|rcsb pdb:3MEK|rcsb pdb:3OXF|rcsb pdb:3OXG|rcsb pdb:3OXL|rcsb pdb:3PDN|rcsb pdb:3QWP|rcsb pdb:3RU0|rcsb pdb:5CCL|rcsb pdb:5CCM|rcsb pdb:5EX0|rcsb pdb:5EX3|rcsb pdb:5HI7|rcsb pdb:5HQ8|rcsb pdb:5V37|rcsb pdb:5XXG|rcsb pdb:5XXJ|rcsb pdb:5YJO|rcsb pdb:6IJL|rcsb pdb:6O9O|rcsb pdb:6P6G|rcsb pdb:6P6K|rcsb pdb:5XXD|rcsb pdb:6P7Z|rcsb pdb:6PAF|rcsb pdb:6YUH|rcsb pdb:7BJ1|reactome:R-HSA-3214841|refseq:XP_011542559.1|refseq:NP_001161212.1|refseq:NP_073580.1|dip:DIP-32653N ensembl:ENSG00000177600(gene)|ensembl:ENST00000321153(transcript)|ensembl:ENST00000530797(transcript)|go:"GO:0002182"(cytoplasmic translational elongation)|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-72689|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|interpro:IPR027534|interpro:IPR038716|interpro:IPR044076|mint:P05387|rcsb pdb:1S4J|rcsb pdb:2JDL|rcsb pdb:2LBF|rcsb pdb:2W1O|rcsb pdb:4BEH|rcsb pdb:4V6X|rcsb pdb:5DDZ|rcsb pdb:5GU4|go:"GO:0003735"(structural constituent of ribosome)|reactome:R-HSA-156827|reactome:R-HSA-156902|refseq:NP_000995.1 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:gKISZLHkhKTIVn2O646c4OQhLzc9606 rogid:IBI+x82JJYg66MPhGKw1/pI/bQA9606 rigid:FXV/vHBYbS4EPkWWP/nXFK9Y1wo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H7B4 uniprotkb:P15531 intact:EBI-347919|ensembl:ENSP00000419184|uniprotkb:Q86TL8|uniprotkb:Q8N5Z6|uniprotkb:Q96AI5|uniprotkb:B1AN38|uniprotkb:A8K0P0 intact:EBI-741141|ensembl:ENSP00000376892|uniprotkb:Q6FGK3|uniprotkb:Q86XQ2|uniprotkb:Q9UDJ6 psi-mi:smyd3_human(display_long)|uniprotkb:SMYD3(gene name)|psi-mi:SMYD3(display_short)|uniprotkb:ZMYND1(gene name synonym)|uniprotkb:ZNFN3A1(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 1(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 3(gene name synonym) psi-mi:ndka_human(display_long)|uniprotkb:Tumor metastatic process-associated protein(gene name synonym)|uniprotkb:Metastasis inhibition factor nm23(gene name synonym)|uniprotkb:Granzyme A-activated DNase(gene name synonym)|uniprotkb:NME1(gene name)|psi-mi:NME1(display_short)|uniprotkb:NDPKA(gene name synonym)|uniprotkb:NM23(gene name synonym)|uniprotkb:NM23-H1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485113|imex:IM-26985-365 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000185420(gene)|ensembl:ENST00000490107(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0014904"(myotube cell development)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR025805|interpro:IPR044420|mint:Q9H7B4|rcsb pdb:3MEK|rcsb pdb:3OXF|rcsb pdb:3OXG|rcsb pdb:3OXL|rcsb pdb:3PDN|rcsb pdb:3QWP|rcsb pdb:3RU0|rcsb pdb:5CCL|rcsb pdb:5CCM|rcsb pdb:5EX0|rcsb pdb:5EX3|rcsb pdb:5HI7|rcsb pdb:5HQ8|rcsb pdb:5V37|rcsb pdb:5XXG|rcsb pdb:5XXJ|rcsb pdb:5YJO|rcsb pdb:6IJL|rcsb pdb:6O9O|rcsb pdb:6P6G|rcsb pdb:6P6K|rcsb pdb:5XXD|rcsb pdb:6P7Z|rcsb pdb:6PAF|rcsb pdb:6YUH|rcsb pdb:7BJ1|reactome:R-HSA-3214841|refseq:XP_011542559.1|refseq:NP_001161212.1|refseq:NP_073580.1|dip:DIP-32653N refseq:NP_000260.1|refseq:NP_937818.1|ensembl:ENSG00000239672(gene)|ensembl:ENST00000393196(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0002762"(negative regulation of myeloid leukocyte differentiation)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004536"(deoxyribonuclease activity)|go:"GO:0004550"(nucleoside diphosphate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0006183"(GTP biosynthetic process)|go:"GO:0006228"(UTP biosynthetic process)|go:"GO:0006241"(CTP biosynthetic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007595"(lactation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014075"(response to amine)|go:"GO:0016020"(membrane)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071398"(cellular response to fatty acid)|interpro:IPR001564(Nucleoside diphosphate kinase, core)|go:"GO:0019899"(enzyme binding)|interpro:IPR023005|go:"GO:0021766"(hippocampus development)|interpro:IPR034907|interpro:IPR036850|mint:P15531|go:"GO:0030154"(cell differentiation)|go:"GO:0032587"(ruffle membrane)|rcsb pdb:1JXV|rcsb pdb:1UCN|go:"GO:0033574"(response to testosterone)|go:"GO:0035690"|rcsb pdb:2HVD|rcsb pdb:2HVE|rcsb pdb:3L7U|rcsb pdb:4ENO|rcsb pdb:5UI4|reactome:R-HSA-499943|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|dip:DIP-39164N - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:gKISZLHkhKTIVn2O646c4OQhLzc9606 rogid:Ut4gK1Xq786CaZzvqdS1eiU5op89606 rigid:FXV/vHBYbS4EPkWWP/nXFK9Y1wo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H7B4 uniprotkb:P68363 intact:EBI-347919|ensembl:ENSP00000419184|uniprotkb:Q86TL8|uniprotkb:Q8N5Z6|uniprotkb:Q96AI5|uniprotkb:B1AN38|uniprotkb:A8K0P0 intact:EBI-487083|intact:EBI-1384226|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:Q27I68|ensembl:ENSP00000336799|uniprotkb:Q8WU19 psi-mi:smyd3_human(display_long)|uniprotkb:SMYD3(gene name)|psi-mi:SMYD3(display_short)|uniprotkb:ZMYND1(gene name synonym)|uniprotkb:ZNFN3A1(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 1(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 3(gene name synonym) psi-mi:tba1b_human(display_long)|uniprotkb:TUBA1B(gene name)|psi-mi:TUBA1B(display_short)|uniprotkb:Tubulin alpha-ubiquitous chain(gene name synonym)|uniprotkb:Alpha-tubulin ubiquitous(gene name synonym)|uniprotkb:Tubulin K-alpha-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485113|imex:IM-26985-365 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000185420(gene)|ensembl:ENST00000490107(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0014904"(myotube cell development)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR025805|interpro:IPR044420|mint:Q9H7B4|rcsb pdb:3MEK|rcsb pdb:3OXF|rcsb pdb:3OXG|rcsb pdb:3OXL|rcsb pdb:3PDN|rcsb pdb:3QWP|rcsb pdb:3RU0|rcsb pdb:5CCL|rcsb pdb:5CCM|rcsb pdb:5EX0|rcsb pdb:5EX3|rcsb pdb:5HI7|rcsb pdb:5HQ8|rcsb pdb:5V37|rcsb pdb:5XXG|rcsb pdb:5XXJ|rcsb pdb:5YJO|rcsb pdb:6IJL|rcsb pdb:6O9O|rcsb pdb:6P6G|rcsb pdb:6P6K|rcsb pdb:5XXD|rcsb pdb:6P7Z|rcsb pdb:6PAF|rcsb pdb:6YUH|rcsb pdb:7BJ1|reactome:R-HSA-3214841|refseq:XP_011542559.1|refseq:NP_001161212.1|refseq:NP_073580.1|dip:DIP-32653N refseq:NP_006073.2|ensembl:ENSG00000123416(gene)|ensembl:ENST00000336023(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-983189|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|go:"GO:0045121"(membrane raft)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68363|rcsb pdb:2E4H|rcsb pdb:5IJ0|rcsb pdb:5IJ9|rcsb pdb:5N5N|rcsb pdb:6E7B|rcsb pdb:6E7C|rcsb pdb:6I2I|go:"GO:0051301"(cell division)|rcsb pdb:6J4V|rcsb pdb:6J8O|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|rcsb pdb:6S8L|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9013407|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-2132295|reactome:R-HSA-9668328 - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:gKISZLHkhKTIVn2O646c4OQhLzc9606 rogid:D4YpuLCXl/S+53qV7P7sF81aARY9606 rigid:FXV/vHBYbS4EPkWWP/nXFK9Y1wo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H7B4 uniprotkb:P61353 intact:EBI-347919|ensembl:ENSP00000419184|uniprotkb:Q86TL8|uniprotkb:Q8N5Z6|uniprotkb:Q96AI5|uniprotkb:B1AN38|uniprotkb:A8K0P0 intact:EBI-352760|uniprotkb:P08526|uniprotkb:Q4G0A9|ensembl:ENSP00000253788|ensembl:ENSP00000464813|ensembl:ENSP00000467587 psi-mi:smyd3_human(display_long)|uniprotkb:SMYD3(gene name)|psi-mi:SMYD3(display_short)|uniprotkb:ZMYND1(gene name synonym)|uniprotkb:ZNFN3A1(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 1(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 3(gene name synonym) psi-mi:rl27_human(display_long)|uniprotkb:RPL27(gene name)|psi-mi:RPL27(display_short)|uniprotkb:Large ribosomal subunit protein eL27(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485113|imex:IM-26985-365 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000185420(gene)|ensembl:ENST00000490107(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0014904"(myotube cell development)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR025805|interpro:IPR044420|mint:Q9H7B4|rcsb pdb:3MEK|rcsb pdb:3OXF|rcsb pdb:3OXG|rcsb pdb:3OXL|rcsb pdb:3PDN|rcsb pdb:3QWP|rcsb pdb:3RU0|rcsb pdb:5CCL|rcsb pdb:5CCM|rcsb pdb:5EX0|rcsb pdb:5EX3|rcsb pdb:5HI7|rcsb pdb:5HQ8|rcsb pdb:5V37|rcsb pdb:5XXG|rcsb pdb:5XXJ|rcsb pdb:5YJO|rcsb pdb:6IJL|rcsb pdb:6O9O|rcsb pdb:6P6G|rcsb pdb:6P6K|rcsb pdb:5XXD|rcsb pdb:6P7Z|rcsb pdb:6PAF|rcsb pdb:6YUH|rcsb pdb:7BJ1|reactome:R-HSA-3214841|refseq:XP_011542559.1|refseq:NP_001161212.1|refseq:NP_073580.1|dip:DIP-32653N rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OLF|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_000979.1|ensembl:ENSG00000131469(gene)|ensembl:ENST00000253788(transcript)|ensembl:ENST00000589037(transcript)|ensembl:ENST00000589913(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|go:"GO:0070062"(extracellular exosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|go:"GO:1904044"(response to aldosterone)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001141(Ribosomal protein L27e)|interpro:IPR005824(KOW)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR018262|interpro:IPR038655|interpro:IPR041991|mint:P61353|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:gKISZLHkhKTIVn2O646c4OQhLzc9606 rogid:TLWbAcdRKUb2ijDYjSUa1sbixis9606 rigid:FXV/vHBYbS4EPkWWP/nXFK9Y1wo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H7B4 uniprotkb:P22413 intact:EBI-347919|ensembl:ENSP00000419184|uniprotkb:Q86TL8|uniprotkb:Q8N5Z6|uniprotkb:Q96AI5|uniprotkb:B1AN38|uniprotkb:A8K0P0 intact:EBI-3197846|ensembl:ENSP00000498074|uniprotkb:Q9UP61|uniprotkb:Q9Y6K3|uniprotkb:Q9NPZ3|uniprotkb:Q5T9R6|uniprotkb:Q9P1P6 psi-mi:smyd3_human(display_long)|uniprotkb:SMYD3(gene name)|psi-mi:SMYD3(display_short)|uniprotkb:ZMYND1(gene name synonym)|uniprotkb:ZNFN3A1(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 1(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 3(gene name synonym) psi-mi:enpp1_human(display_long)|uniprotkb:ENPP1(gene name)|psi-mi:ENPP1(display_short)|uniprotkb:M6S1(gene name synonym)|uniprotkb:NPPS(gene name synonym)|uniprotkb:PC1(gene name synonym)|uniprotkb:PDNP1(gene name synonym)|uniprotkb:Membrane component chromosome 6 surface marker 1(gene name synonym)|uniprotkb:Phosphodiesterase I/nucleotide pyrophosphatase 1(gene name synonym)|uniprotkb:Plasma-cell membrane glycoprotein PC-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485113|imex:IM-26985-365 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000185420(gene)|ensembl:ENST00000490107(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0014904"(myotube cell development)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR025805|interpro:IPR044420|mint:Q9H7B4|rcsb pdb:3MEK|rcsb pdb:3OXF|rcsb pdb:3OXG|rcsb pdb:3OXL|rcsb pdb:3PDN|rcsb pdb:3QWP|rcsb pdb:3RU0|rcsb pdb:5CCL|rcsb pdb:5CCM|rcsb pdb:5EX0|rcsb pdb:5EX3|rcsb pdb:5HI7|rcsb pdb:5HQ8|rcsb pdb:5V37|rcsb pdb:5XXG|rcsb pdb:5XXJ|rcsb pdb:5YJO|rcsb pdb:6IJL|rcsb pdb:6O9O|rcsb pdb:6P6G|rcsb pdb:6P6K|rcsb pdb:5XXD|rcsb pdb:6P7Z|rcsb pdb:6PAF|rcsb pdb:6YUH|rcsb pdb:7BJ1|reactome:R-HSA-3214841|refseq:XP_011542559.1|refseq:NP_001161212.1|refseq:NP_073580.1|dip:DIP-32653N rcsb pdb:6WEV|rcsb pdb:6WEW|rcsb pdb:6WFJ|reactome:R-HSA-196843|reactome:R-HSA-199220|rcsb pdb:6WEU|ensembl:ENSG00000197594(gene)|ensembl:ENST00000647893(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0004528"(phosphodiesterase I activity)|go:"GO:0004551"(nucleotide diphosphatase activity)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006091"(generation of precursor metabolites and energy)|go:"GO:0006796"(phosphate-containing compound metabolic process)|go:"GO:0006955"(immune response)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009143"(nucleoside triphosphate catabolic process)|go:"GO:0009986"(cell surface)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030247"(polysaccharide binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030318"(melanocyte differentiation)|go:"GO:0030500"(regulation of bone mineralization)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0030505"(inorganic diphosphate transport)|go:"GO:0030643"(cellular phosphate ion homeostasis)|go:"GO:0030730"(sequestering of triglyceride)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0031953"(negative regulation of protein autophosphorylation)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035529"(NADH pyrophosphatase activity)|go:"GO:0036218"(dTTP diphosphatase activity)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045719"(negative regulation of glycogen biosynthetic process)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046325"(negative regulation of glucose import)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0047429"(nucleoside-triphosphate diphosphatase activity)|go:"GO:0050427"(3'-phosphoadenosine 5'-phosphosulfate metabolic process)|go:"GO:0050656"(3'-phosphoadenosine 5'-phosphosulfate binding)|go:"GO:0090305"(nucleic acid phosphodiester bond hydrolysis)|go:"GO:0106177"(cyclic-GMP-AMP hydrolase activity)|go:"GO:1990787"(negative regulation of hh target transcription factor activity)|interpro:IPR001212(Somatomedin B)|interpro:IPR001604(DNA/RNA non-specific endonuclease)|interpro:IPR002591(Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase)|interpro:IPR017850(Alkaline-phosphatase-like, core domain)|interpro:IPR020436|interpro:IPR020821|interpro:IPR029890|interpro:IPR036024|mint:P22413|rcsb pdb:2YS0|rcsb pdb:6WET|refseq:NP_006199.2 - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:gKISZLHkhKTIVn2O646c4OQhLzc9606 rogid:5qr5E+tfmPJFgXtvePCm+fDs9ks9606 rigid:FXV/vHBYbS4EPkWWP/nXFK9Y1wo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H7B4 uniprotkb:Q16540 intact:EBI-347919|ensembl:ENSP00000419184|uniprotkb:Q86TL8|uniprotkb:Q8N5Z6|uniprotkb:Q96AI5|uniprotkb:B1AN38|uniprotkb:A8K0P0 intact:EBI-1046141|uniprotkb:A8MT29|uniprotkb:Q96Q71|ensembl:ENSP00000370930|ensembl:ENSP00000380466|ensembl:ENSP00000500123|ensembl:ENSP00000500896 psi-mi:smyd3_human(display_long)|uniprotkb:SMYD3(gene name)|psi-mi:SMYD3(display_short)|uniprotkb:ZMYND1(gene name synonym)|uniprotkb:ZNFN3A1(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 1(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 3(gene name synonym) psi-mi:rm23_human(display_long)|uniprotkb:L23 mitochondrial-related protein(gene name synonym)|uniprotkb:Ribosomal protein L23-like(gene name synonym)|uniprotkb:L23MRP(gene name synonym)|uniprotkb:RPL23L(gene name synonym)|uniprotkb:MRPL23(gene name)|psi-mi:MRPL23(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein uL23m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485113|imex:IM-26985-365 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000185420(gene)|ensembl:ENST00000490107(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0014904"(myotube cell development)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR025805|interpro:IPR044420|mint:Q9H7B4|rcsb pdb:3MEK|rcsb pdb:3OXF|rcsb pdb:3OXG|rcsb pdb:3OXL|rcsb pdb:3PDN|rcsb pdb:3QWP|rcsb pdb:3RU0|rcsb pdb:5CCL|rcsb pdb:5CCM|rcsb pdb:5EX0|rcsb pdb:5EX3|rcsb pdb:5HI7|rcsb pdb:5HQ8|rcsb pdb:5V37|rcsb pdb:5XXG|rcsb pdb:5XXJ|rcsb pdb:5YJO|rcsb pdb:6IJL|rcsb pdb:6O9O|rcsb pdb:6P6G|rcsb pdb:6P6K|rcsb pdb:5XXD|rcsb pdb:6P7Z|rcsb pdb:6PAF|rcsb pdb:6YUH|rcsb pdb:7BJ1|reactome:R-HSA-3214841|refseq:XP_011542559.1|refseq:NP_001161212.1|refseq:NP_073580.1|dip:DIP-32653N refseq:NP_066957.3|ensembl:ENSG00000214026(gene)|ensembl:ENSG00000288141(gene)|ensembl:ENST00000381519(transcript)|ensembl:ENST00000397298(transcript)|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|ensembl:ENST00000672185(transcript)|ensembl:ENST00000672523(transcript)|go:"GO:0001650"(fibrillar center)|rcsb pdb:7ODS|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR013025(Ribosomal protein L25/L23)|mint:Q16540|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:7ODT|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:7OF0 - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:gKISZLHkhKTIVn2O646c4OQhLzc9606 rogid:1TSlowXDlWVOW2PS1vv8Lu/e1vU9606 rigid:FXV/vHBYbS4EPkWWP/nXFK9Y1wo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H7B4 uniprotkb:P51648 intact:EBI-347919|ensembl:ENSP00000419184|uniprotkb:Q86TL8|uniprotkb:Q8N5Z6|uniprotkb:Q96AI5|uniprotkb:B1AN38|uniprotkb:A8K0P0 intact:EBI-1391128|uniprotkb:Q93011|uniprotkb:Q96J37|uniprotkb:Q6I9T3|ensembl:ENSP00000176643|ensembl:ENSP00000461916|ensembl:ENSP00000463637|ensembl:ENSP00000500092 psi-mi:smyd3_human(display_long)|uniprotkb:SMYD3(gene name)|psi-mi:SMYD3(display_short)|uniprotkb:ZMYND1(gene name synonym)|uniprotkb:ZNFN3A1(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 1(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 3(gene name synonym) psi-mi:al3a2_human(display_long)|uniprotkb:Aldehyde dehydrogenase 10(gene name synonym)|uniprotkb:Microsomal aldehyde dehydrogenase(gene name synonym)|uniprotkb:ALDH3A2(gene name)|psi-mi:ALDH3A2(display_short)|uniprotkb:ALDH10(gene name synonym)|uniprotkb:FALDH(gene name synonym)|uniprotkb:Fatty aldehyde dehydrogenase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485113|imex:IM-26985-365 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000185420(gene)|ensembl:ENST00000490107(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0014904"(myotube cell development)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR025805|interpro:IPR044420|mint:Q9H7B4|rcsb pdb:3MEK|rcsb pdb:3OXF|rcsb pdb:3OXG|rcsb pdb:3OXL|rcsb pdb:3PDN|rcsb pdb:3QWP|rcsb pdb:3RU0|rcsb pdb:5CCL|rcsb pdb:5CCM|rcsb pdb:5EX0|rcsb pdb:5EX3|rcsb pdb:5HI7|rcsb pdb:5HQ8|rcsb pdb:5V37|rcsb pdb:5XXG|rcsb pdb:5XXJ|rcsb pdb:5YJO|rcsb pdb:6IJL|rcsb pdb:6O9O|rcsb pdb:6P6G|rcsb pdb:6P6K|rcsb pdb:5XXD|rcsb pdb:6P7Z|rcsb pdb:6PAF|rcsb pdb:6YUH|rcsb pdb:7BJ1|reactome:R-HSA-3214841|refseq:XP_011542559.1|refseq:NP_001161212.1|refseq:NP_073580.1|dip:DIP-32653N refseq:NP_000373.1|refseq:NP_001026976.1|refseq:XP_011522034.1|refseq:XP_011522035.1|refseq:XP_016879845.1|refseq:XP_016879846.1|ensembl:ENST00000672357(transcript)|go:"GO:0004028"(3-chloroallyl aldehyde dehydrogenase activity)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006081"(cellular aldehyde metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006714"(sesquiterpenoid metabolic process)|go:"GO:0007417"(central nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0008544"(epidermis development)|go:"GO:0016021"(integral component of membrane)|go:"GO:0033306"(phytol metabolic process)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043878"("glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity")|go:"GO:0046458"(hexadecanal metabolic process)|go:"GO:0046577"(long-chain-alcohol oxidase activity)|go:"GO:0050061"(long-chain-aldehyde dehydrogenase activity)|go:"GO:0052814"(medium-chain-aldehyde dehydrogenase activity)|interpro:IPR012394("Aldehyde dehydrogenase NAD(P)-dependent")|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|mint:P51648|rcsb pdb:4QGK|reactome:R-HSA-1660661|reactome:R-HSA-389599|reactome:R-HSA-9603798|reactome:R-HSA-9609523|reactome:R-HSA-9696270|reactome:R-HSA-9696273|ensembl:ENSG00000072210(gene)|ensembl:ENST00000176643(transcript)|ensembl:ENST00000579855(transcript)|ensembl:ENST00000581518(transcript) - - comment:"author score: 27" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:gKISZLHkhKTIVn2O646c4OQhLzc9606 rogid:ADi5/NMf5JsjzaonzFIbHZebIlQ9606 rigid:FXV/vHBYbS4EPkWWP/nXFK9Y1wo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H7B4 uniprotkb:Q13084 intact:EBI-347919|ensembl:ENSP00000419184|uniprotkb:Q86TL8|uniprotkb:Q8N5Z6|uniprotkb:Q96AI5|uniprotkb:B1AN38|uniprotkb:A8K0P0 intact:EBI-723426|uniprotkb:Q4TT39|uniprotkb:Q96S26|uniprotkb:Q9BQD8|uniprotkb:Q9BR04|ensembl:ENSP00000199706|ensembl:ENSP00000374326|ensembl:ENSP00000497004|uniprotkb:B2RCM4|uniprotkb:D3DU46 psi-mi:smyd3_human(display_long)|uniprotkb:SMYD3(gene name)|psi-mi:SMYD3(display_short)|uniprotkb:ZMYND1(gene name synonym)|uniprotkb:ZNFN3A1(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 1(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 3(gene name synonym) psi-mi:rm28_human(display_long)|uniprotkb:Melanoma antigen p15(gene name synonym)|uniprotkb:MRPL28(gene name)|psi-mi:MRPL28(display_short)|uniprotkb:MAAT1(gene name synonym)|uniprotkb:Melanoma-associated antigen recognized by T-lymphocytes(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein bL28m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485113|imex:IM-26985-365 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000185420(gene)|ensembl:ENST00000490107(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0014904"(myotube cell development)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR025805|interpro:IPR044420|mint:Q9H7B4|rcsb pdb:3MEK|rcsb pdb:3OXF|rcsb pdb:3OXG|rcsb pdb:3OXL|rcsb pdb:3PDN|rcsb pdb:3QWP|rcsb pdb:3RU0|rcsb pdb:5CCL|rcsb pdb:5CCM|rcsb pdb:5EX0|rcsb pdb:5EX3|rcsb pdb:5HI7|rcsb pdb:5HQ8|rcsb pdb:5V37|rcsb pdb:5XXG|rcsb pdb:5XXJ|rcsb pdb:5YJO|rcsb pdb:6IJL|rcsb pdb:6O9O|rcsb pdb:6P6G|rcsb pdb:6P6K|rcsb pdb:5XXD|rcsb pdb:6P7Z|rcsb pdb:6PAF|rcsb pdb:6YUH|rcsb pdb:7BJ1|reactome:R-HSA-3214841|refseq:XP_011542559.1|refseq:NP_001161212.1|refseq:NP_073580.1|dip:DIP-32653N refseq:NP_006419.2|rcsb pdb:3J7Y|ensembl:ENSG00000086504(gene)|ensembl:ENST00000199706(transcript)|ensembl:ENST00000389675(transcript)|ensembl:ENST00000648346(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|interpro:IPR026569|interpro:IPR034704|interpro:IPR037147|mint:Q13084|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:XP_011520653.1|refseq:XP_005255098.1|dip:DIP-61135N - - comment:"author score: 27" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:gKISZLHkhKTIVn2O646c4OQhLzc9606 rogid:rgjK24sQlABM210ZM7T9mT2wxKs9606 rigid:FXV/vHBYbS4EPkWWP/nXFK9Y1wo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H7B4 uniprotkb:Q8IXM3 intact:EBI-347919|ensembl:ENSP00000419184|uniprotkb:Q86TL8|uniprotkb:Q8N5Z6|uniprotkb:Q96AI5|uniprotkb:B1AN38|uniprotkb:A8K0P0 intact:EBI-912501|uniprotkb:Q96Q49|ensembl:ENSP00000360498 psi-mi:smyd3_human(display_long)|uniprotkb:SMYD3(gene name)|psi-mi:SMYD3(display_short)|uniprotkb:ZMYND1(gene name synonym)|uniprotkb:ZNFN3A1(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 1(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 3(gene name synonym) psi-mi:rm41_human(display_long)|uniprotkb:MRPL27(gene name synonym)|uniprotkb:39S ribosomal protein L27 homolog(gene name synonym)|uniprotkb:MRP-L27 homolog(gene name synonym)|uniprotkb:Bcl-2-interacting mitochondrial ribosomal protein L41(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 3 protein(gene name synonym)|uniprotkb:MRPL41(gene name)|psi-mi:MRPL41(display_short)|uniprotkb:BMRP(gene name synonym)|uniprotkb:RPML27(gene name synonym)|uniprotkb:PIG3(orf name)|uniprotkb:Mitochondrial large ribosomal subunit protein mL41(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485113|imex:IM-26985-365 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000185420(gene)|ensembl:ENST00000490107(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0014904"(myotube cell development)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR025805|interpro:IPR044420|mint:Q9H7B4|rcsb pdb:3MEK|rcsb pdb:3OXF|rcsb pdb:3OXG|rcsb pdb:3OXL|rcsb pdb:3PDN|rcsb pdb:3QWP|rcsb pdb:3RU0|rcsb pdb:5CCL|rcsb pdb:5CCM|rcsb pdb:5EX0|rcsb pdb:5EX3|rcsb pdb:5HI7|rcsb pdb:5HQ8|rcsb pdb:5V37|rcsb pdb:5XXG|rcsb pdb:5XXJ|rcsb pdb:5YJO|rcsb pdb:6IJL|rcsb pdb:6O9O|rcsb pdb:6P6G|rcsb pdb:6P6K|rcsb pdb:5XXD|rcsb pdb:6P7Z|rcsb pdb:6PAF|rcsb pdb:6YUH|rcsb pdb:7BJ1|reactome:R-HSA-3214841|refseq:XP_011542559.1|refseq:NP_001161212.1|refseq:NP_073580.1|dip:DIP-32653N refseq:NP_115866.1|ensembl:ENSG00000182154(gene)|ensembl:ENST00000371443(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR019189|mint:Q8IXM3|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - comment:"author score: 29" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:gKISZLHkhKTIVn2O646c4OQhLzc9606 rogid:1qftd9Vr6Rsymp6hgM29FeOvChA9606 rigid:FXV/vHBYbS4EPkWWP/nXFK9Y1wo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H7B4 uniprotkb:P04745 intact:EBI-347919|ensembl:ENSP00000419184|uniprotkb:Q86TL8|uniprotkb:Q8N5Z6|uniprotkb:Q96AI5|uniprotkb:B1AN38|uniprotkb:A8K0P0 intact:EBI-738586|uniprotkb:Q13763|uniprotkb:A6NJS5|uniprotkb:A8K8H6|uniprotkb:Q5T083 psi-mi:smyd3_human(display_long)|uniprotkb:SMYD3(gene name)|psi-mi:SMYD3(display_short)|uniprotkb:ZMYND1(gene name synonym)|uniprotkb:ZNFN3A1(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 1(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 3(gene name synonym) psi-mi:amy1a_human(display_long)|uniprotkb:AMY1A(gene name)|psi-mi:AMY1A(display_short)|uniprotkb:AMY1(gene name synonym)|uniprotkb:1,4-alpha-D-glucan glucanohydrolase 1(gene name synonym)|uniprotkb:Salivary alpha-amylase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485113|imex:IM-26985-365 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000185420(gene)|ensembl:ENST00000490107(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0014904"(myotube cell development)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR025805|interpro:IPR044420|mint:Q9H7B4|rcsb pdb:3MEK|rcsb pdb:3OXF|rcsb pdb:3OXG|rcsb pdb:3OXL|rcsb pdb:3PDN|rcsb pdb:3QWP|rcsb pdb:3RU0|rcsb pdb:5CCL|rcsb pdb:5CCM|rcsb pdb:5EX0|rcsb pdb:5EX3|rcsb pdb:5HI7|rcsb pdb:5HQ8|rcsb pdb:5V37|rcsb pdb:5XXG|rcsb pdb:5XXJ|rcsb pdb:5YJO|rcsb pdb:6IJL|rcsb pdb:6O9O|rcsb pdb:6P6G|rcsb pdb:6P6K|rcsb pdb:5XXD|rcsb pdb:6P7Z|rcsb pdb:6PAF|rcsb pdb:6YUH|rcsb pdb:7BJ1|reactome:R-HSA-3214841|refseq:XP_011542559.1|refseq:NP_001161212.1|refseq:NP_073580.1|dip:DIP-32653N ensembl:ENST00000330330|ensembl:ENST00000370079|ensembl:ENST00000370080|ensembl:ENST00000370083|refseq:NP_001008219.1|refseq:NP_001008220.1|refseq:NP_001008222.1|refseq:NP_004029.2|interpro:IPR006048(Alpha-amylase, C-terminal all beta)|interpro:IPR006046(Glycoside hydrolase family 13)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|go:"GO:0004556"(alpha-amylase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0005975"(carbohydrate metabolic process)|rcsb pdb:1C8Q|rcsb pdb:1JXJ|rcsb pdb:1JXK|rcsb pdb:1MFU|rcsb pdb:1MFV|rcsb pdb:1NM9|rcsb pdb:1Q4N|rcsb pdb:1SMD|rcsb pdb:1XV8|rcsb pdb:1Z32|rcsb pdb:3BLK|rcsb pdb:3BLP|rcsb pdb:3DHP|refseq:XP_016856547.1|interpro:IPR031319|reactome:R-HSA-189085|go:"GO:0005615"(extracellular space)|go:"GO:0070062"(extracellular exosome)|refseq:XP_011539564.1|refseq:NP_001333709.1|ensembl:ENSG00000174876|ensembl:ENSG00000187733|ensembl:ENSG00000237763|ensembl:ENSP00000330484|ensembl:ENSP00000359096|ensembl:ENSP00000359097|ensembl:ENSP00000359100|go:"GO:0103025"|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta) - - caution:This sequence has been withdrawn from Uniprot.|comment:"author score: 37" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:gKISZLHkhKTIVn2O646c4OQhLzc9606 rogid:Gwt64Wrt6IUZmCIxM3CXQxe7W509606 rigid:FXV/vHBYbS4EPkWWP/nXFK9Y1wo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H7B4 uniprotkb:Q9HD33 intact:EBI-347919|ensembl:ENSP00000419184|uniprotkb:Q86TL8|uniprotkb:Q8N5Z6|uniprotkb:Q96AI5|uniprotkb:B1AN38|uniprotkb:A8K0P0 intact:EBI-2560181|uniprotkb:Q8N5D1|uniprotkb:Q6XRG1|ensembl:ENSP00000417602 psi-mi:smyd3_human(display_long)|uniprotkb:SMYD3(gene name)|psi-mi:SMYD3(display_short)|uniprotkb:ZMYND1(gene name synonym)|uniprotkb:ZNFN3A1(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 1(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 3(gene name synonym) psi-mi:rm47_human(display_long)|uniprotkb:MRPL47(gene name)|psi-mi:MRPL47(display_short)|uniprotkb:NCM1(gene name synonym)|uniprotkb:Nasopharyngeal carcinoma metastasis-related protein 1(gene name synonym)|uniprotkb:CGI-204(orf name)|uniprotkb:Mitochondrial large ribosomal subunit protein uL29m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485113|imex:IM-26985-365 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000185420(gene)|ensembl:ENST00000490107(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0014904"(myotube cell development)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR025805|interpro:IPR044420|mint:Q9H7B4|rcsb pdb:3MEK|rcsb pdb:3OXF|rcsb pdb:3OXG|rcsb pdb:3OXL|rcsb pdb:3PDN|rcsb pdb:3QWP|rcsb pdb:3RU0|rcsb pdb:5CCL|rcsb pdb:5CCM|rcsb pdb:5EX0|rcsb pdb:5EX3|rcsb pdb:5HI7|rcsb pdb:5HQ8|rcsb pdb:5V37|rcsb pdb:5XXG|rcsb pdb:5XXJ|rcsb pdb:5YJO|rcsb pdb:6IJL|rcsb pdb:6O9O|rcsb pdb:6P6G|rcsb pdb:6P6K|rcsb pdb:5XXD|rcsb pdb:6P7Z|rcsb pdb:6PAF|rcsb pdb:6YUH|rcsb pdb:7BJ1|reactome:R-HSA-3214841|refseq:XP_011542559.1|refseq:NP_001161212.1|refseq:NP_073580.1|dip:DIP-32653N refseq:NP_065142.2|refseq:NP_817125.1|ensembl:ENSG00000136522(gene)|ensembl:ENST00000476781(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR010729(Ribosomal protein L47, mitochondrial)|interpro:IPR038340|mint:Q9HD33|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU3|rcsb pdb:6NU2|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - comment:"author score: 37" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:gKISZLHkhKTIVn2O646c4OQhLzc9606 rogid:Zwk2kFYyc2Efry0CU19e8o7GEW89606 rigid:FXV/vHBYbS4EPkWWP/nXFK9Y1wo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H7B4 uniprotkb:Q96A35 intact:EBI-347919|ensembl:ENSP00000419184|uniprotkb:Q86TL8|uniprotkb:Q8N5Z6|uniprotkb:Q96AI5|uniprotkb:B1AN38|uniprotkb:A8K0P0 intact:EBI-1045743|uniprotkb:Q53G65|uniprotkb:Q53HT0|uniprotkb:Q5SYZ9|uniprotkb:Q5SZ00|uniprotkb:Q5SZ02|uniprotkb:Q96Q70|uniprotkb:Q9H7G3|uniprotkb:D3DVC8|intact:EBI-2560246|ensembl:ENSP00000354525|ensembl:ENSP00000357194 psi-mi:smyd3_human(display_long)|uniprotkb:SMYD3(gene name)|psi-mi:SMYD3(display_short)|uniprotkb:ZMYND1(gene name synonym)|uniprotkb:ZNFN3A1(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 1(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 3(gene name synonym) psi-mi:rm24_human(display_long)|uniprotkb:MRPL24(gene name)|psi-mi:MRPL24(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein uL24m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485113|imex:IM-26985-365 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000185420(gene)|ensembl:ENST00000490107(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001162"(RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0014904"(myotube cell development)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR025805|interpro:IPR044420|mint:Q9H7B4|rcsb pdb:3MEK|rcsb pdb:3OXF|rcsb pdb:3OXG|rcsb pdb:3OXL|rcsb pdb:3PDN|rcsb pdb:3QWP|rcsb pdb:3RU0|rcsb pdb:5CCL|rcsb pdb:5CCM|rcsb pdb:5EX0|rcsb pdb:5EX3|rcsb pdb:5HI7|rcsb pdb:5HQ8|rcsb pdb:5V37|rcsb pdb:5XXG|rcsb pdb:5XXJ|rcsb pdb:5YJO|rcsb pdb:6IJL|rcsb pdb:6O9O|rcsb pdb:6P6G|rcsb pdb:6P6K|rcsb pdb:5XXD|rcsb pdb:6P7Z|rcsb pdb:6PAF|rcsb pdb:6YUH|rcsb pdb:7BJ1|reactome:R-HSA-3214841|refseq:XP_011542559.1|refseq:NP_001161212.1|refseq:NP_073580.1|dip:DIP-32653N refseq:NP_078816.2|refseq:NP_663781.1|ensembl:ENSG00000143314(gene)|ensembl:ENST00000361531(transcript)|ensembl:ENST00000368211(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|interpro:IPR003256(Ribosomal protein L24)|interpro:IPR005824(KOW)|interpro:IPR005825(Ribosomal protein L24/L26, conserved site)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041988|mint:Q96A35|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:6ZSE|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:XP_011508283.1|refseq:XP_011508284.1 - - comment:"author score: 46" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:gKISZLHkhKTIVn2O646c4OQhLzc9606 rogid:TVDcxc2+oUe0eez+iQPW5HWBwdI9606 rigid:FXV/vHBYbS4EPkWWP/nXFK9Y1wo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IYR2 uniprotkb:Q8TEM1 intact:EBI-3956972|uniprotkb:Q8N1P2|uniprotkb:Q8NAT0|uniprotkb:Q96LV4|uniprotkb:Q96PV2|ensembl:ENSP00000304360 intact:EBI-372826|uniprotkb:A6NN56|uniprotkb:O94980|uniprotkb:Q6NXG6|uniprotkb:Q8NBJ1|uniprotkb:Q9H6C8|uniprotkb:Q9UFP3|ensembl:ENSP00000254508 psi-mi:smyd4_human(display_long)|uniprotkb:SMYD4(gene name)|psi-mi:SMYD4(display_short)|uniprotkb:KIAA1936(gene name synonym) psi-mi:po210_human(display_long)|uniprotkb:KIAA0906(gene name synonym)|uniprotkb:NUP210(gene name)|psi-mi:NUP210(display_short)|uniprotkb:PSEC0245(orf name)|uniprotkb:Nuclear envelope pore membrane protein POM 210(gene name synonym)|uniprotkb:Pore membrane protein of 210 kDa(gene name synonym)|uniprotkb:Nucleoporin Nup210(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485167|imex:IM-26985-133 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_443160.2|ensembl:ENSG00000186532(gene)|ensembl:ENST00000305513(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0032259"(methylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR044421|mint:Q8IYR2 reactome:R-HSA-9610379|refseq:NP_079199.2|ensembl:ENSG00000132182(gene)|ensembl:ENST00000254508(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0051028"(mRNA transport)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR003343(Bacterial Ig-like, group 2)|interpro:IPR008964(Invasin/intimin cell-adhesion)|mint:Q8TEM1|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MnFA0J4IghVE8z7L5IiEkZ9Lmaw9606 rogid:udIemFThWYk0VC21Ml4EDDQWXlg9606 rigid:NMmGItq7v2Twa9k7lhJ92uMgKfw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IYR2 uniprotkb:P10412 intact:EBI-3956972|uniprotkb:Q8N1P2|uniprotkb:Q8NAT0|uniprotkb:Q96LV4|uniprotkb:Q96PV2|ensembl:ENSP00000304360 intact:EBI-358163|uniprotkb:Q4VB25|ensembl:ENSP00000307705 psi-mi:smyd4_human(display_long)|uniprotkb:SMYD4(gene name)|psi-mi:SMYD4(display_short)|uniprotkb:KIAA1936(gene name synonym) psi-mi:h14_human(display_long)|uniprotkb:H1-4(gene name)|psi-mi:H1-4(display_short)|uniprotkb:H1F4(gene name synonym)|uniprotkb:HIST1H1E(gene name synonym)|uniprotkb:Histone H1b(gene name synonym)|uniprotkb:Histone H1s-4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485167|imex:IM-26985-133 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_443160.2|ensembl:ENSG00000186532(gene)|ensembl:ENST00000305513(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0032259"(methylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR044421|mint:Q8IYR2 refseq:NP_005312.1|rcsb pdb:6H8P|rcsb pdb:7K5Y|rcsb pdb:7K63|go:"GO:0032564"(dATP binding)|go:"GO:0043531"(ADP binding)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P10412|rcsb pdb:3TZD|rcsb pdb:5JJZ|reactome:R-HSA-140342|reactome:R-HSA-2559584|ensembl:ENSG00000168298(gene)|ensembl:ENST00000304218(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0000792"(heterochromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016208"(AMP binding)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing) - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MnFA0J4IghVE8z7L5IiEkZ9Lmaw9606 rogid:yT8wBbspLLR8G3DrgpFeWEOPgac9606 rigid:NMmGItq7v2Twa9k7lhJ92uMgKfw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8IYR2 uniprotkb:P68363 intact:EBI-3956972|uniprotkb:Q8N1P2|uniprotkb:Q8NAT0|uniprotkb:Q96LV4|uniprotkb:Q96PV2|ensembl:ENSP00000304360 intact:EBI-487083|intact:EBI-1384226|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:Q27I68|ensembl:ENSP00000336799|uniprotkb:Q8WU19 psi-mi:smyd4_human(display_long)|uniprotkb:SMYD4(gene name)|psi-mi:SMYD4(display_short)|uniprotkb:KIAA1936(gene name synonym) psi-mi:tba1b_human(display_long)|uniprotkb:TUBA1B(gene name)|psi-mi:TUBA1B(display_short)|uniprotkb:Tubulin alpha-ubiquitous chain(gene name synonym)|uniprotkb:Alpha-tubulin ubiquitous(gene name synonym)|uniprotkb:Tubulin K-alpha-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485167|imex:IM-26985-133 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_443160.2|ensembl:ENSG00000186532(gene)|ensembl:ENST00000305513(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007507"(heart development)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0032259"(methylation)|go:"GO:0046872"(metal ion binding)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR044421|mint:Q8IYR2 refseq:NP_006073.2|ensembl:ENSG00000123416(gene)|ensembl:ENST00000336023(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-983189|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|go:"GO:0045121"(membrane raft)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68363|rcsb pdb:2E4H|rcsb pdb:5IJ0|rcsb pdb:5IJ9|rcsb pdb:5N5N|rcsb pdb:6E7B|rcsb pdb:6E7C|rcsb pdb:6I2I|go:"GO:0051301"(cell division)|rcsb pdb:6J4V|rcsb pdb:6J8O|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|rcsb pdb:6S8L|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9013407|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-2132295|reactome:R-HSA-9668328 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MnFA0J4IghVE8z7L5IiEkZ9Lmaw9606 rogid:D4YpuLCXl/S+53qV7P7sF81aARY9606 rigid:NMmGItq7v2Twa9k7lhJ92uMgKfw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6GMV2 uniprotkb:P81605 intact:EBI-11057552|uniprotkb:Q13558|uniprotkb:D6W5H3|ensembl:ENSP00000374152 intact:EBI-395625|uniprotkb:P58461|uniprotkb:A5JHP2|uniprotkb:A5JHP3|uniprotkb:Q53YJ2|ensembl:ENSP00000293371 psi-mi:smyd5_human(display_long)|uniprotkb:SET and MYND domain-containing protein 5(gene name synonym)|uniprotkb:[histone H4]-lysine20 N-trimethyltransferase SMYD5(gene name synonym)|uniprotkb:SMYD5(gene name)|psi-mi:SMYD5(display_short)|uniprotkb:Protein NN8-4AG(gene name synonym)|uniprotkb:RAI15(gene name synonym)|uniprotkb:Retinoic acid-induced protein 15(gene name synonym) psi-mi:dcd_human(display_long)|uniprotkb:AIDD(gene name synonym)|uniprotkb:DSEP(gene name synonym)|uniprotkb:Preproteolysin(gene name synonym)|uniprotkb:DCD(gene name)|psi-mi:DCD(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485182|imex:IM-26985-285 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006053.2|ensembl:ENSG00000135632(gene)|ensembl:ENST00000389501(transcript)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0046872"(metal ion binding)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR001214(SET)|interpro:IPR044422|mint:Q6GMV2 refseq:NP_444513.1|refseq:NP_001287783.1|ensembl:ENSG00000161634(gene)|ensembl:ENST00000293371(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008233"(peptidase activity)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR028130|interpro:IPR043557|mint:P81605|rcsb pdb:2KSG|rcsb pdb:2NDK|rcsb pdb:2YMK|rcsb pdb:6SHK|reactome:R-HSA-6803157 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:VJhF4521PkZ59wOQyvbfa4oYz489606 rogid:M8PkKVWx98nhtd79ods05mqw8Ls9606 rigid:WPIOKVEN4fGusCkMOi2S9Kz5cIU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6GMV2 uniprotkb:Q9NZC7 intact:EBI-11057552|uniprotkb:Q13558|uniprotkb:D6W5H3|ensembl:ENSP00000374152 intact:EBI-4320739|uniprotkb:A8K323|uniprotkb:Q5MYT5|uniprotkb:Q96KM3|uniprotkb:Q96RF2|uniprotkb:Q9BTT8|uniprotkb:Q9NPC9|uniprotkb:Q9NRF4|uniprotkb:Q9NRF5|uniprotkb:Q9NRF6|uniprotkb:Q9NRK1|uniprotkb:Q9NZC5|ensembl:ENSP00000457230 psi-mi:smyd5_human(display_long)|uniprotkb:SET and MYND domain-containing protein 5(gene name synonym)|uniprotkb:[histone H4]-lysine20 N-trimethyltransferase SMYD5(gene name synonym)|uniprotkb:SMYD5(gene name)|psi-mi:SMYD5(display_short)|uniprotkb:Protein NN8-4AG(gene name synonym)|uniprotkb:RAI15(gene name synonym)|uniprotkb:Retinoic acid-induced protein 15(gene name synonym) psi-mi:wwox_human(display_long)|uniprotkb:WWOX(gene name)|psi-mi:WWOX(display_short)|uniprotkb:FOR(gene name synonym)|uniprotkb:WOX1(gene name synonym)|uniprotkb:Fragile site FRA16D oxidoreductase(gene name synonym)|uniprotkb:SDR41C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 41C member 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485182|imex:IM-26985-285 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_006053.2|ensembl:ENSG00000135632(gene)|ensembl:ENST00000389501(transcript)|go:"GO:0010529"(negative regulation of transposition)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0046872"(metal ion binding)|go:"GO:2000035"(regulation of stem cell division)|go:"GO:2000736"(regulation of stem cell differentiation)|interpro:IPR001214(SET)|interpro:IPR044422|mint:Q6GMV2 refseq:NP_057457.1|refseq:NP_570607.1|refseq:NP_001278926.1|ensembl:ENST00000566780(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR036020|interpro:IPR036291|interpro:IPR042732|mint:Q9NZC7|rcsb pdb:1WMV|reactome:R-HSA-1251985|reactome:R-HSA-8866904|reactome:R-HSA-8866907|ensembl:ENSG00000186153(gene) - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:VJhF4521PkZ59wOQyvbfa4oYz489606 rogid:YMGESSlld4QIPoFrcPX3zhwIy2E9606 rigid:WPIOKVEN4fGusCkMOi2S9Kz5cIU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P16104 uniprotkb:Q7KZF4 intact:EBI-494830|uniprotkb:Q4ZGJ7|uniprotkb:Q6IAS5|ensembl:ENSP00000364310|ensembl:ENSP00000434024 intact:EBI-1044112|uniprotkb:Q13122|ensembl:ENSP00000346762|uniprotkb:Q96AG0 psi-mi:h2ax_human(display_long)|uniprotkb:H2AX(gene name)|psi-mi:H2AX(display_short)|uniprotkb:H2AFX(gene name synonym)|uniprotkb:Histone H2A.X(gene name synonym) psi-mi:snd1_human(display_long)|uniprotkb:100 kDa coactivator(gene name synonym)|uniprotkb:EBNA2 coactivator p100(gene name synonym)|uniprotkb:Tudor domain-containing protein 11(gene name synonym)|uniprotkb:SND1(gene name)|psi-mi:SND1(display_short)|uniprotkb:p100 co-activator(gene name synonym)|uniprotkb:TDRD11(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25485194|imex:IM-26985-135 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000188486(gene)|ensembl:ENST00000375167(transcript)|ensembl:ENST00000530167(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000786"(nucleosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|refseq:NP_002096.1|dip:DIP-33604N|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|go:"GO:0005813"(centrosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090398"(cellular senescence)|go:"GO:0090734"(site of DNA damage)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P16104|rcsb pdb:1YDP|rcsb pdb:2AZM|rcsb pdb:2D31|rcsb pdb:2DYP|rcsb pdb:3SHV|rcsb pdb:3SQD|rcsb pdb:3SZM|rcsb pdb:3U3Z|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K refseq:NP_055205.2|ensembl:ENSG00000197157(gene)|ensembl:ENST00000354725(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0042470"(melanosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097433"(dense body)|go:"GO:1905172"(RISC complex binding)|interpro:IPR002071(Thermonuclease active site)|interpro:IPR002999(Tudor)|interpro:IPR016071("Staphylococcal nuclease (SNase-like), OB-fold")|interpro:IPR016685(RNA-induced silencing complex, nuclease component Tudor-SN)|interpro:IPR035437|mint:Q7KZF4|rcsb pdb:2E6N|rcsb pdb:2HQE|rcsb pdb:2HQX|rcsb pdb:2O4X|rcsb pdb:3BDL|rcsb pdb:3OMC|rcsb pdb:3OMG|rcsb pdb:4QMG|rcsb pdb:5M9O|reactome:R-HSA-6802952|dip:DIP-29613N - comment:"author score: 18" - figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:VQoEp3F8lEBTOj+PDDUzrJCQNZA9606 rogid:I9JNlRfASs5dwk0JZQ+F+GsW94g9606 rigid:f5E9ZlnLjg0OLz2coSUe91sVBOM false - tandem tag:n-n - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NRG4 uniprotkb:Q2QGD7 intact:EBI-1055671|uniprotkb:Q4V765|uniprotkb:Q5VSH9|uniprotkb:Q96AI4|uniprotkb:B2R9P9|uniprotkb:I6L9H7|ensembl:ENSP00000355924 intact:EBI-1538838|uniprotkb:Q7L3L1|uniprotkb:Q8NAU2|uniprotkb:C5J0H9|uniprotkb:Q6DKI8|ensembl:ENSP00000374359|intact:EBI-28981670 psi-mi:smyd2_human(display_long)|uniprotkb:KMT3C(gene name synonym)|uniprotkb:HSKM-B(gene name synonym)|uniprotkb:Lysine N-methyltransferase 3C(gene name synonym)|uniprotkb:SMYD2(gene name)|psi-mi:SMYD2(display_short)|uniprotkb:Histone methyltransferase SMYD2(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 2(gene name synonym) psi-mi:zxdc_human(display_long)|uniprotkb:ZXDC(gene name)|psi-mi:ZXDC(display_short)|uniprotkb:ZXDL(gene name synonym)|uniprotkb:ZXD-like zinc finger protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485032|imex:IM-26985-283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064582.2|ensembl:ENSG00000143499(gene)|ensembl:ENST00000366957(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR044419|mint:Q9NRG4|rcsb pdb:3RIB|rcsb pdb:3S7B|rcsb pdb:3S7D|rcsb pdb:3S7F|rcsb pdb:3S7J|rcsb pdb:3TG4|rcsb pdb:3TG5|rcsb pdb:4O6F|rcsb pdb:4WUY|rcsb pdb:4YND|rcsb pdb:5ARF|rcsb pdb:5ARG|rcsb pdb:5KJK|rcsb pdb:5KJL|rcsb pdb:5KJM|rcsb pdb:5KJN|rcsb pdb:5V3H|rcsb pdb:5WCG|rcsb pdb:6CBX|rcsb pdb:6CBY|rcsb pdb:6MON|rcsb pdb:6N3G|reactome:R-HSA-3214841|reactome:R-HSA-6804760|go:"GO:0034968"(histone lysine methylation)|dip:DIP-50202N refseq:NP_001035743.1|refseq:NP_079388.3|ensembl:ENST00000336332|ensembl:ENSP00000337694|ensembl:ENSP00000374359|ensembl:ENSG00000070476(gene)|ensembl:ENST00000389709(transcript)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030275"(LRR domain binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070742"(C2H2 zinc finger domain binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q2QGD7 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:97p8/OfJphcdOJsbap20djvk1nU9606 rogid:2oqRV2O8vmW9f6FeX+td6cvhyNI9606 rigid:F1SP2bzWuu+sRZ+3ZMLyCqS1TRs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NRG4 uniprotkb:P31948 intact:EBI-1055671|uniprotkb:Q4V765|uniprotkb:Q5VSH9|uniprotkb:Q96AI4|uniprotkb:B2R9P9|uniprotkb:I6L9H7|ensembl:ENSP00000355924 intact:EBI-1054052|uniprotkb:Q5TZU9|intact:EBI-4404694|uniprotkb:B4DM70|uniprotkb:F5H0T1|uniprotkb:G3XAD8|uniprotkb:Q3ZCU9|ensembl:ENSP00000305958 psi-mi:smyd2_human(display_long)|uniprotkb:KMT3C(gene name synonym)|uniprotkb:HSKM-B(gene name synonym)|uniprotkb:Lysine N-methyltransferase 3C(gene name synonym)|uniprotkb:SMYD2(gene name)|psi-mi:SMYD2(display_short)|uniprotkb:Histone methyltransferase SMYD2(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 2(gene name synonym) psi-mi:stip1_human(display_long)|uniprotkb:Hsc70/Hsp90-organizing protein(gene name synonym)|uniprotkb:STIP1(gene name)|psi-mi:STIP1(display_short)|uniprotkb:Transformation-sensitive protein IEF SSP 3521(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-11(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485032|imex:IM-26985-283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064582.2|ensembl:ENSG00000143499(gene)|ensembl:ENST00000366957(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR044419|mint:Q9NRG4|rcsb pdb:3RIB|rcsb pdb:3S7B|rcsb pdb:3S7D|rcsb pdb:3S7F|rcsb pdb:3S7J|rcsb pdb:3TG4|rcsb pdb:3TG5|rcsb pdb:4O6F|rcsb pdb:4WUY|rcsb pdb:4YND|rcsb pdb:5ARF|rcsb pdb:5ARG|rcsb pdb:5KJK|rcsb pdb:5KJL|rcsb pdb:5KJM|rcsb pdb:5KJN|rcsb pdb:5V3H|rcsb pdb:5WCG|rcsb pdb:6CBX|rcsb pdb:6CBY|rcsb pdb:6MON|rcsb pdb:6N3G|reactome:R-HSA-3214841|reactome:R-HSA-6804760|go:"GO:0034968"(histone lysine methylation)|dip:DIP-50202N refseq:NP_006810.1|ensembl:ENSG00000168439(gene)|ensembl:ENST00000305218(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0101031"(chaperone complex)|go:"GO:0120293"(dynein axonemal particle)|interpro:IPR006636(Heat shock chaperonin-binding)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013105(Tetratricopeptide TPR2)|interpro:IPR019734|interpro:IPR041243|mint:P31948|rcsb pdb:1ELR|rcsb pdb:1ELW|rcsb pdb:2LNI|rcsb pdb:2NC9|rcsb pdb:3ESK|rcsb pdb:3FWV|reactome:R-HSA-3371497|reactome:R-HSA-9696273|refseq:NP_001269581.1|refseq:NP_001269582.1|dip:DIP-41085N - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:97p8/OfJphcdOJsbap20djvk1nU9606 rogid:/encEzabIj7I9YdYaYY2UvRG3Pg9606 rigid:F1SP2bzWuu+sRZ+3ZMLyCqS1TRs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NRG4 uniprotkb:P55036 intact:EBI-1055671|uniprotkb:Q4V765|uniprotkb:Q5VSH9|uniprotkb:Q96AI4|uniprotkb:B2R9P9|uniprotkb:I6L9H7|ensembl:ENSP00000355924 intact:EBI-359318|uniprotkb:Q5VWC5|uniprotkb:Q9NS92|uniprotkb:D3DV16|ensembl:ENSP00000357879 psi-mi:smyd2_human(display_long)|uniprotkb:KMT3C(gene name synonym)|uniprotkb:HSKM-B(gene name synonym)|uniprotkb:Lysine N-methyltransferase 3C(gene name synonym)|uniprotkb:SMYD2(gene name)|psi-mi:SMYD2(display_short)|uniprotkb:Histone methyltransferase SMYD2(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 2(gene name synonym) psi-mi:psmd4_human(display_long)|uniprotkb:PSMD4(gene name)|psi-mi:PSMD4(display_short)|uniprotkb:MCB1(gene name synonym)|uniprotkb:26S proteasome regulatory subunit S5A(gene name synonym)|uniprotkb:26S proteasome regulatory subunit RPN10(gene name synonym)|uniprotkb:Multiubiquitin chain-binding protein(gene name synonym)|uniprotkb:Antisecretory factor 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485032|imex:IM-26985-283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064582.2|ensembl:ENSG00000143499(gene)|ensembl:ENST00000366957(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR044419|mint:Q9NRG4|rcsb pdb:3RIB|rcsb pdb:3S7B|rcsb pdb:3S7D|rcsb pdb:3S7F|rcsb pdb:3S7J|rcsb pdb:3TG4|rcsb pdb:3TG5|rcsb pdb:4O6F|rcsb pdb:4WUY|rcsb pdb:4YND|rcsb pdb:5ARF|rcsb pdb:5ARG|rcsb pdb:5KJK|rcsb pdb:5KJL|rcsb pdb:5KJM|rcsb pdb:5KJN|rcsb pdb:5V3H|rcsb pdb:5WCG|rcsb pdb:6CBX|rcsb pdb:6CBY|rcsb pdb:6MON|rcsb pdb:6N3G|reactome:R-HSA-3214841|reactome:R-HSA-6804760|go:"GO:0034968"(histone lysine methylation)|dip:DIP-50202N refseq:NP_002801.1|dip:DIP-38189N|ensembl:ENSG00000159352(gene)|ensembl:ENST00000368884(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008540"(proteasome regulatory particle, base subcomplex)|go:"GO:0022624"(proteasome accessory complex)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043248"(proteasome assembly)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR036465|mint:P55036|rcsb pdb:1P9C|rcsb pdb:1P9D|rcsb pdb:1UEL|rcsb pdb:1YX4|rcsb pdb:1YX5|rcsb pdb:1YX6|rcsb pdb:2KDE|rcsb pdb:2KDF|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4K|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:5VGZ|rcsb pdb:5VHF|rcsb pdb:5VHH|rcsb pdb:5VHI|rcsb pdb:5VHS|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6MUN|rcsb pdb:6U19|rcsb pdb:6WJD|rcsb pdb:6WJN|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:97p8/OfJphcdOJsbap20djvk1nU9606 rogid:FTJG3ns3Ag/Y3xP3yEydGxppRcA9606 rigid:F1SP2bzWuu+sRZ+3ZMLyCqS1TRs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NRG4 uniprotkb:P40616 intact:EBI-1055671|uniprotkb:Q4V765|uniprotkb:Q5VSH9|uniprotkb:Q96AI4|uniprotkb:B2R9P9|uniprotkb:I6L9H7|ensembl:ENSP00000355924 intact:EBI-1052746|uniprotkb:P80417|uniprotkb:Q53XB1|uniprotkb:B4DWW1|ensembl:ENSP00000261636|intact:EBI-11157530 psi-mi:smyd2_human(display_long)|uniprotkb:KMT3C(gene name synonym)|uniprotkb:HSKM-B(gene name synonym)|uniprotkb:Lysine N-methyltransferase 3C(gene name synonym)|uniprotkb:SMYD2(gene name)|psi-mi:SMYD2(display_short)|uniprotkb:Histone methyltransferase SMYD2(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 2(gene name synonym) psi-mi:arl1_human(display_long)|uniprotkb:ARL1(gene name)|psi-mi:ARL1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485032|imex:IM-26985-283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064582.2|ensembl:ENSG00000143499(gene)|ensembl:ENST00000366957(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR044419|mint:Q9NRG4|rcsb pdb:3RIB|rcsb pdb:3S7B|rcsb pdb:3S7D|rcsb pdb:3S7F|rcsb pdb:3S7J|rcsb pdb:3TG4|rcsb pdb:3TG5|rcsb pdb:4O6F|rcsb pdb:4WUY|rcsb pdb:4YND|rcsb pdb:5ARF|rcsb pdb:5ARG|rcsb pdb:5KJK|rcsb pdb:5KJL|rcsb pdb:5KJM|rcsb pdb:5KJN|rcsb pdb:5V3H|rcsb pdb:5WCG|rcsb pdb:6CBX|rcsb pdb:6CBY|rcsb pdb:6MON|rcsb pdb:6N3G|reactome:R-HSA-3214841|reactome:R-HSA-6804760|go:"GO:0034968"(histone lysine methylation)|dip:DIP-50202N refseq:NP_001168.1|ensembl:ENSG00000120805(gene)|ensembl:ENST00000261636(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0009404"(toxin metabolic process)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031584"(activation of phospholipase D activity)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0046872"(metal ion binding)|go:"GO:0048193"(Golgi vesicle transport)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P40616|rcsb pdb:1UPT|rcsb pdb:4DCN|rcsb pdb:5EE5|rcsb pdb:5J5C|reactome:R-HSA-6811440|interpro:IPR005225(Small GTP-binding protein) - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:97p8/OfJphcdOJsbap20djvk1nU9606 rogid:4sRUSYrH1mt5ol85HlMNSEn1j9M9606 rigid:F1SP2bzWuu+sRZ+3ZMLyCqS1TRs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NRG4 uniprotkb:Q06210 intact:EBI-1055671|uniprotkb:Q4V765|uniprotkb:Q5VSH9|uniprotkb:Q96AI4|uniprotkb:B2R9P9|uniprotkb:I6L9H7|ensembl:ENSP00000355924 intact:EBI-1055540|uniprotkb:Q9BXF8|uniprotkb:Q53QE6|ensembl:ENSP00000349860 psi-mi:smyd2_human(display_long)|uniprotkb:KMT3C(gene name synonym)|uniprotkb:HSKM-B(gene name synonym)|uniprotkb:Lysine N-methyltransferase 3C(gene name synonym)|uniprotkb:SMYD2(gene name)|psi-mi:SMYD2(display_short)|uniprotkb:Histone methyltransferase SMYD2(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 2(gene name synonym) psi-mi:gfpt1_human(display_long)|uniprotkb:D-fructose-6-phosphate amidotransferase 1(gene name synonym)|uniprotkb:Hexosephosphate aminotransferase 1(gene name synonym)|uniprotkb:GFPT1(gene name)|psi-mi:GFPT1(display_short)|uniprotkb:GFAT(gene name synonym)|uniprotkb:GFPT(gene name synonym)|uniprotkb:"Glutamine:fructose-6-phosphate amidotransferase 1"(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485032|imex:IM-26985-283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064582.2|ensembl:ENSG00000143499(gene)|ensembl:ENST00000366957(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR044419|mint:Q9NRG4|rcsb pdb:3RIB|rcsb pdb:3S7B|rcsb pdb:3S7D|rcsb pdb:3S7F|rcsb pdb:3S7J|rcsb pdb:3TG4|rcsb pdb:3TG5|rcsb pdb:4O6F|rcsb pdb:4WUY|rcsb pdb:4YND|rcsb pdb:5ARF|rcsb pdb:5ARG|rcsb pdb:5KJK|rcsb pdb:5KJL|rcsb pdb:5KJM|rcsb pdb:5KJN|rcsb pdb:5V3H|rcsb pdb:5WCG|rcsb pdb:6CBX|rcsb pdb:6CBY|rcsb pdb:6MON|rcsb pdb:6N3G|reactome:R-HSA-3214841|reactome:R-HSA-6804760|go:"GO:0034968"(histone lysine methylation)|dip:DIP-50202N refseq:NP_002047.2|refseq:NP_001231639.1|ensembl:ENSG00000198380(gene)|ensembl:ENST00000357308(transcript)|go:"GO:0004360"("glutamine-fructose-6-phosphate transaminase (isomerizing) activity")|go:"GO:0005829"(cytosol)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0006047"(UDP-N-acetylglucosamine metabolic process)|go:"GO:0006048"(UDP-N-acetylglucosamine biosynthetic process)|go:"GO:0006112"(energy reserve metabolic process)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097367"(carbohydrate derivative binding)|interpro:IPR001347("Sugar isomerase (SIS)")|interpro:IPR005855(Glucosamine-fructose-6-phosphate aminotransferase, isomerising)|interpro:IPR017932|interpro:IPR029055|interpro:IPR035466|interpro:IPR035490|mint:Q06210|rcsb pdb:2V4M|rcsb pdb:2ZJ3|rcsb pdb:2ZJ4|rcsb pdb:6R4E|rcsb pdb:6R4F|rcsb pdb:6R4G|rcsb pdb:6R4H|rcsb pdb:6R4I|rcsb pdb:6R4J|rcsb pdb:6SVM|rcsb pdb:6SVO|rcsb pdb:6SVP|rcsb pdb:6SVQ|rcsb pdb:6ZMJ|rcsb pdb:6ZMK|rcsb pdb:7NDL|reactome:R-HSA-381038|reactome:R-HSA-4085023|reactome:R-HSA-446210 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:97p8/OfJphcdOJsbap20djvk1nU9606 rogid:fP9V7Qv/Wv8EaxMa0lrY4icjCno9606 rigid:F1SP2bzWuu+sRZ+3ZMLyCqS1TRs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NRG4 uniprotkb:Q9BRX2 intact:EBI-1055671|uniprotkb:Q4V765|uniprotkb:Q5VSH9|uniprotkb:Q96AI4|uniprotkb:B2R9P9|uniprotkb:I6L9H7|ensembl:ENSP00000355924 intact:EBI-1043580|uniprotkb:Q9GZS6|uniprotkb:Q9Y306|ensembl:ENSP00000274311 psi-mi:smyd2_human(display_long)|uniprotkb:KMT3C(gene name synonym)|uniprotkb:HSKM-B(gene name synonym)|uniprotkb:Lysine N-methyltransferase 3C(gene name synonym)|uniprotkb:SMYD2(gene name)|psi-mi:SMYD2(display_short)|uniprotkb:Histone methyltransferase SMYD2(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 2(gene name synonym) psi-mi:pelo_human(display_long)|uniprotkb:PELO(gene name)|psi-mi:PELO(display_short)|uniprotkb:CGI-17(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485032|imex:IM-26985-283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064582.2|ensembl:ENSG00000143499(gene)|ensembl:ENST00000366957(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR044419|mint:Q9NRG4|rcsb pdb:3RIB|rcsb pdb:3S7B|rcsb pdb:3S7D|rcsb pdb:3S7F|rcsb pdb:3S7J|rcsb pdb:3TG4|rcsb pdb:3TG5|rcsb pdb:4O6F|rcsb pdb:4WUY|rcsb pdb:4YND|rcsb pdb:5ARF|rcsb pdb:5ARG|rcsb pdb:5KJK|rcsb pdb:5KJL|rcsb pdb:5KJM|rcsb pdb:5KJN|rcsb pdb:5V3H|rcsb pdb:5WCG|rcsb pdb:6CBX|rcsb pdb:6CBY|rcsb pdb:6MON|rcsb pdb:6N3G|reactome:R-HSA-3214841|reactome:R-HSA-6804760|go:"GO:0034968"(histone lysine methylation)|dip:DIP-50202N ensembl:ENSG00000152684(gene)|ensembl:ENST00000274311(transcript)|go:"GO:0001833"(inner cell mass cell proliferation)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006417"(regulation of translation)|go:"GO:0007049"(cell cycle)|go:"GO:0007492"(endoderm development)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0032790"(ribosome disassembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051276"(chromosome organization)|go:"GO:0051301"(cell division)|go:"GO:0060231"(mesenchymal to epithelial transition)|go:"GO:0070481"(nuclear-transcribed mRNA catabolic process, non-stop decay)|go:"GO:0070651"(nonfunctional rRNA decay)|go:"GO:0070966"(nuclear-transcribed mRNA catabolic process, no-go decay)|go:"GO:0071025"(RNA surveillance)|interpro:IPR004405(Probable translation factor pelota)|interpro:IPR005140(eRF1 domain 1)|interpro:IPR005141(eRF1 domain 2)|interpro:IPR005142(eRF1 domain 3)|interpro:IPR029064|interpro:IPR038069|interpro:IPR042226|mint:Q9BRX2|rcsb pdb:1X52|rcsb pdb:5EO3|rcsb pdb:5LZW|rcsb pdb:5LZX|rcsb pdb:5LZY|rcsb pdb:5LZZ|refseq:NP_057030.3 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:97p8/OfJphcdOJsbap20djvk1nU9606 rogid:EZIi8JN2tu0u4oH06fOus3LKjoo9606 rigid:F1SP2bzWuu+sRZ+3ZMLyCqS1TRs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NRG4 uniprotkb:Q16543 intact:EBI-1055671|uniprotkb:Q4V765|uniprotkb:Q5VSH9|uniprotkb:Q96AI4|uniprotkb:B2R9P9|uniprotkb:I6L9H7|ensembl:ENSP00000355924 intact:EBI-295634|uniprotkb:Q53YA2|ensembl:ENSP00000222005 psi-mi:smyd2_human(display_long)|uniprotkb:KMT3C(gene name synonym)|uniprotkb:HSKM-B(gene name synonym)|uniprotkb:Lysine N-methyltransferase 3C(gene name synonym)|uniprotkb:SMYD2(gene name)|psi-mi:SMYD2(display_short)|uniprotkb:Histone methyltransferase SMYD2(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 2(gene name synonym) psi-mi:cdc37_human(display_long)|uniprotkb:CDC37(gene name)|psi-mi:CDC37(display_short)|uniprotkb:Hsp90 chaperone protein kinase-targeting subunit(gene name synonym)|uniprotkb:p50Cdc37(gene name synonym)|uniprotkb:CDC37A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485032|imex:IM-26985-283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064582.2|ensembl:ENSG00000143499(gene)|ensembl:ENST00000366957(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR044419|mint:Q9NRG4|rcsb pdb:3RIB|rcsb pdb:3S7B|rcsb pdb:3S7D|rcsb pdb:3S7F|rcsb pdb:3S7J|rcsb pdb:3TG4|rcsb pdb:3TG5|rcsb pdb:4O6F|rcsb pdb:4WUY|rcsb pdb:4YND|rcsb pdb:5ARF|rcsb pdb:5ARG|rcsb pdb:5KJK|rcsb pdb:5KJL|rcsb pdb:5KJM|rcsb pdb:5KJN|rcsb pdb:5V3H|rcsb pdb:5WCG|rcsb pdb:6CBX|rcsb pdb:6CBY|rcsb pdb:6MON|rcsb pdb:6N3G|reactome:R-HSA-3214841|reactome:R-HSA-6804760|go:"GO:0034968"(histone lysine methylation)|dip:DIP-50202N refseq:NP_008996.1|dip:DIP-27560N|ensembl:ENSG00000105401(gene)|ensembl:ENST00000222005(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006605"(protein targeting)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060334"(regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098779"(positive regulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0101031"(chaperone complex)|go:"GO:1990565"(HSP90-CDC37 chaperone complex)|interpro:IPR004918(Cdc37)|interpro:IPR013855(Cdc37, N-terminal)|interpro:IPR013873(Cdc37, C-terminal)|interpro:IPR013874(Cdc37, Hsp90 binding)|interpro:IPR038189|mint:Q16543|rcsb pdb:1US7|rcsb pdb:2K5B|rcsb pdb:2N5X|rcsb pdb:2NCA|rcsb pdb:2W0G|rcsb pdb:5FWK|rcsb pdb:5FWL|rcsb pdb:5FWM|rcsb pdb:5FWP|rcsb pdb:5HPE|reactome:R-HSA-1227986|reactome:R-HSA-1236382|reactome:R-HSA-5637810|reactome:R-HSA-5675482|reactome:R-HSA-8863795|reactome:R-HSA-9013418|reactome:R-HSA-9634285|reactome:R-HSA-9652282|reactome:R-HSA-9664565|reactome:R-HSA-9665233|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:97p8/OfJphcdOJsbap20djvk1nU9606 rogid:iajhitd2iEmd17KfpU/nMaKc4049606 rigid:F1SP2bzWuu+sRZ+3ZMLyCqS1TRs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NRG4 uniprotkb:Q9UNQ2 intact:EBI-1055671|uniprotkb:Q4V765|uniprotkb:Q5VSH9|uniprotkb:Q96AI4|uniprotkb:B2R9P9|uniprotkb:I6L9H7|ensembl:ENSP00000355924 intact:EBI-395738|uniprotkb:O76025|uniprotkb:Q9BU77|uniprotkb:Q9UES1|ensembl:ENSP00000199320 psi-mi:smyd2_human(display_long)|uniprotkb:KMT3C(gene name synonym)|uniprotkb:HSKM-B(gene name synonym)|uniprotkb:Lysine N-methyltransferase 3C(gene name synonym)|uniprotkb:SMYD2(gene name)|psi-mi:SMYD2(display_short)|uniprotkb:Histone methyltransferase SMYD2(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 2(gene name synonym) psi-mi:dim1_human(display_long)|uniprotkb:DIMT1L(gene name synonym)|uniprotkb:DIM1 dimethyladenosine transferase 1 homolog(gene name synonym)|uniprotkb:DIM1 dimethyladenosine transferase 1-like(gene name synonym)|uniprotkb:HUSSY-05(orf name)|uniprotkb:"Probable 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase"(gene name synonym)|uniprotkb:Probable 18S rRNA dimethylase(gene name synonym)|uniprotkb:DIMT1(gene name)|psi-mi:DIMT1(display_short)|uniprotkb:"Probable S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase"(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485032|imex:IM-26985-283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064582.2|ensembl:ENSG00000143499(gene)|ensembl:ENST00000366957(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR044419|mint:Q9NRG4|rcsb pdb:3RIB|rcsb pdb:3S7B|rcsb pdb:3S7D|rcsb pdb:3S7F|rcsb pdb:3S7J|rcsb pdb:3TG4|rcsb pdb:3TG5|rcsb pdb:4O6F|rcsb pdb:4WUY|rcsb pdb:4YND|rcsb pdb:5ARF|rcsb pdb:5ARG|rcsb pdb:5KJK|rcsb pdb:5KJL|rcsb pdb:5KJM|rcsb pdb:5KJN|rcsb pdb:5V3H|rcsb pdb:5WCG|rcsb pdb:6CBX|rcsb pdb:6CBY|rcsb pdb:6MON|rcsb pdb:6N3G|reactome:R-HSA-3214841|reactome:R-HSA-6804760|go:"GO:0034968"(histone lysine methylation)|dip:DIP-50202N refseq:NP_055288.1|ensembl:ENSG00000086189(gene)|ensembl:ENST00000199320(transcript)|go:"GO:0000179"("rRNA (adenine-N6,N6-)-dimethyltransferase activity")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0031167"(rRNA methylation)|go:"GO:0052909"("18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity")|go:"GO:2000234"(positive regulation of rRNA processing)|interpro:IPR001737(Ribosomal RNA adenine methylase transferase)|interpro:IPR011530(rRNA adenine dimethylase)|interpro:IPR020596|interpro:IPR020598|interpro:IPR029063|mint:Q9UNQ2|rcsb pdb:1ZQ9|rcsb pdb:6W6C|rcsb pdb:6W6F|reactome:R-HSA-6790901|refseq:NP_001335005.1 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:97p8/OfJphcdOJsbap20djvk1nU9606 rogid:hx0FRrx+XTeoziOqfesiw4KL+wo9606 rigid:F1SP2bzWuu+sRZ+3ZMLyCqS1TRs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NRG4 uniprotkb:Q71UM5 intact:EBI-1055671|uniprotkb:Q4V765|uniprotkb:Q5VSH9|uniprotkb:Q96AI4|uniprotkb:B2R9P9|uniprotkb:I6L9H7|ensembl:ENSP00000355924 intact:EBI-355126|uniprotkb:Q9BTJ1|ensembl:ENSP00000331019 psi-mi:smyd2_human(display_long)|uniprotkb:KMT3C(gene name synonym)|uniprotkb:HSKM-B(gene name synonym)|uniprotkb:Lysine N-methyltransferase 3C(gene name synonym)|uniprotkb:SMYD2(gene name)|psi-mi:SMYD2(display_short)|uniprotkb:Histone methyltransferase SMYD2(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 2(gene name synonym) psi-mi:rs27l_human(display_long)|uniprotkb:RPS27L(gene name)|psi-mi:RPS27L(display_short)|uniprotkb:Small ribosomal subunit protein eS27-like(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485032|imex:IM-26985-283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064582.2|ensembl:ENSG00000143499(gene)|ensembl:ENST00000366957(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR044419|mint:Q9NRG4|rcsb pdb:3RIB|rcsb pdb:3S7B|rcsb pdb:3S7D|rcsb pdb:3S7F|rcsb pdb:3S7J|rcsb pdb:3TG4|rcsb pdb:3TG5|rcsb pdb:4O6F|rcsb pdb:4WUY|rcsb pdb:4YND|rcsb pdb:5ARF|rcsb pdb:5ARG|rcsb pdb:5KJK|rcsb pdb:5KJL|rcsb pdb:5KJM|rcsb pdb:5KJN|rcsb pdb:5V3H|rcsb pdb:5WCG|rcsb pdb:6CBX|rcsb pdb:6CBY|rcsb pdb:6MON|rcsb pdb:6N3G|reactome:R-HSA-3214841|reactome:R-HSA-6804760|go:"GO:0034968"(histone lysine methylation)|dip:DIP-50202N refseq:NP_057004.1|ensembl:ENSG00000185088(gene)|ensembl:ENST00000330964(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0006412"(translation)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008494"(translation activator activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046872"(metal ion binding)|interpro:IPR000592(Ribosomal protein S27e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR023407|mint:Q71UM5|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:97p8/OfJphcdOJsbap20djvk1nU9606 rogid:OVIAlDF6dN3DxLZgQFrFl8r0Z0I9606 rigid:F1SP2bzWuu+sRZ+3ZMLyCqS1TRs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NRG4 uniprotkb:P62273 intact:EBI-1055671|uniprotkb:Q4V765|uniprotkb:Q5VSH9|uniprotkb:Q96AI4|uniprotkb:B2R9P9|uniprotkb:I6L9H7|ensembl:ENSP00000355924 intact:EBI-1054121|uniprotkb:P30054|uniprotkb:A8MZ73|ensembl:ENSP00000245458|ensembl:ENSP00000495033 psi-mi:smyd2_human(display_long)|uniprotkb:KMT3C(gene name synonym)|uniprotkb:HSKM-B(gene name synonym)|uniprotkb:Lysine N-methyltransferase 3C(gene name synonym)|uniprotkb:SMYD2(gene name)|psi-mi:SMYD2(display_short)|uniprotkb:Histone methyltransferase SMYD2(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 2(gene name synonym) psi-mi:rs29_human(display_long)|uniprotkb:RPS29(gene name)|psi-mi:RPS29(display_short)|uniprotkb:Small ribosomal subunit protein uS14(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485032|imex:IM-26985-283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064582.2|ensembl:ENSG00000143499(gene)|ensembl:ENST00000366957(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR044419|mint:Q9NRG4|rcsb pdb:3RIB|rcsb pdb:3S7B|rcsb pdb:3S7D|rcsb pdb:3S7F|rcsb pdb:3S7J|rcsb pdb:3TG4|rcsb pdb:3TG5|rcsb pdb:4O6F|rcsb pdb:4WUY|rcsb pdb:4YND|rcsb pdb:5ARF|rcsb pdb:5ARG|rcsb pdb:5KJK|rcsb pdb:5KJL|rcsb pdb:5KJM|rcsb pdb:5KJN|rcsb pdb:5V3H|rcsb pdb:5WCG|rcsb pdb:6CBX|rcsb pdb:6CBY|rcsb pdb:6MON|rcsb pdb:6N3G|reactome:R-HSA-3214841|reactome:R-HSA-6804760|go:"GO:0034968"(histone lysine methylation)|dip:DIP-50202N refseq:NP_001023.1|refseq:NP_001025172.1|ensembl:ENSG00000213741(gene)|ensembl:ENST00000245458(transcript)|ensembl:ENST00000556230(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|interpro:IPR001209(Ribosomal protein S14)|interpro:IPR018271|interpro:IPR039744|interpro:IPR043140|mint:P62273|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:97p8/OfJphcdOJsbap20djvk1nU9606 rogid:vMgvFs6gwidbpv837yH2u0sSIAU9606 rigid:F1SP2bzWuu+sRZ+3ZMLyCqS1TRs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NRG4 uniprotkb:P11908 intact:EBI-1055671|uniprotkb:Q4V765|uniprotkb:Q5VSH9|uniprotkb:Q96AI4|uniprotkb:B2R9P9|uniprotkb:I6L9H7|ensembl:ENSP00000355924 intact:EBI-4290895|uniprotkb:Q0VDH9|uniprotkb:Q0VDI0|uniprotkb:Q15245|uniprotkb:Q2TAK7|ensembl:ENSP00000370043 psi-mi:smyd2_human(display_long)|uniprotkb:KMT3C(gene name synonym)|uniprotkb:HSKM-B(gene name synonym)|uniprotkb:Lysine N-methyltransferase 3C(gene name synonym)|uniprotkb:SMYD2(gene name)|psi-mi:SMYD2(display_short)|uniprotkb:Histone methyltransferase SMYD2(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 2(gene name synonym) psi-mi:prps2_human(display_long)|uniprotkb:PPRibP(gene name synonym)|uniprotkb:Phosphoribosyl pyrophosphate synthase II(gene name synonym)|uniprotkb:PRPS2(gene name)|psi-mi:PRPS2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485032|imex:IM-26985-283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064582.2|ensembl:ENSG00000143499(gene)|ensembl:ENST00000366957(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR044419|mint:Q9NRG4|rcsb pdb:3RIB|rcsb pdb:3S7B|rcsb pdb:3S7D|rcsb pdb:3S7F|rcsb pdb:3S7J|rcsb pdb:3TG4|rcsb pdb:3TG5|rcsb pdb:4O6F|rcsb pdb:4WUY|rcsb pdb:4YND|rcsb pdb:5ARF|rcsb pdb:5ARG|rcsb pdb:5KJK|rcsb pdb:5KJL|rcsb pdb:5KJM|rcsb pdb:5KJN|rcsb pdb:5V3H|rcsb pdb:5WCG|rcsb pdb:6CBX|rcsb pdb:6CBY|rcsb pdb:6MON|rcsb pdb:6N3G|reactome:R-HSA-3214841|reactome:R-HSA-6804760|go:"GO:0034968"(histone lysine methylation)|dip:DIP-50202N refseq:NP_001034180.1|refseq:NP_002756.1|ensembl:ENSG00000101911(gene)|ensembl:ENST00000380668(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002189"(ribose phosphate diphosphokinase complex)|go:"GO:0004749"(ribose phosphate diphosphokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006015"(5-phosphoribose 1-diphosphate biosynthetic process)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006164"(purine nucleotide biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0009156"(ribonucleoside monophosphate biosynthetic process)|go:"GO:0016301"(kinase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|interpro:IPR000836(Phosphoribosyltransferase)|interpro:IPR000842(Phosphoribosyl pyrophosphate synthetase, conserved site)|interpro:IPR005946(Phosphoribosyl pyrophosphokinase)|interpro:IPR029057|interpro:IPR029099|interpro:IPR037515|mint:P11908|reactome:R-HSA-73843 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:97p8/OfJphcdOJsbap20djvk1nU9606 rogid:0xrvWRbZcFgGYCIUnf0XtqHvJ9E9606 rigid:F1SP2bzWuu+sRZ+3ZMLyCqS1TRs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NRG4 uniprotkb:Q8IZ69 intact:EBI-1055671|uniprotkb:Q4V765|uniprotkb:Q5VSH9|uniprotkb:Q96AI4|uniprotkb:B2R9P9|uniprotkb:I6L9H7|ensembl:ENSP00000355924 intact:EBI-2515774|uniprotkb:Q9H732|uniprotkb:Q32P57|uniprotkb:Q96ME6|uniprotkb:D3DX25|ensembl:ENSP00000252136|ensembl:ENSP00000385807 psi-mi:smyd2_human(display_long)|uniprotkb:KMT3C(gene name synonym)|uniprotkb:HSKM-B(gene name synonym)|uniprotkb:Lysine N-methyltransferase 3C(gene name synonym)|uniprotkb:SMYD2(gene name)|psi-mi:SMYD2(display_short)|uniprotkb:Histone methyltransferase SMYD2(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 2(gene name synonym) psi-mi:trm2a_human(display_long)|uniprotkb:TRMT2A(gene name)|psi-mi:TRMT2A(display_short)|uniprotkb:HTF9C(gene name synonym)|uniprotkb:HpaII tiny fragments locus 9c protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485032|imex:IM-26985-283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064582.2|ensembl:ENSG00000143499(gene)|ensembl:ENST00000366957(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR044419|mint:Q9NRG4|rcsb pdb:3RIB|rcsb pdb:3S7B|rcsb pdb:3S7D|rcsb pdb:3S7F|rcsb pdb:3S7J|rcsb pdb:3TG4|rcsb pdb:3TG5|rcsb pdb:4O6F|rcsb pdb:4WUY|rcsb pdb:4YND|rcsb pdb:5ARF|rcsb pdb:5ARG|rcsb pdb:5KJK|rcsb pdb:5KJL|rcsb pdb:5KJM|rcsb pdb:5KJN|rcsb pdb:5V3H|rcsb pdb:5WCG|rcsb pdb:6CBX|rcsb pdb:6CBY|rcsb pdb:6MON|rcsb pdb:6N3G|reactome:R-HSA-3214841|reactome:R-HSA-6804760|go:"GO:0034968"(histone lysine methylation)|dip:DIP-50202N refseq:NP_073564.3|refseq:NP_892029.2|refseq:NP_001244923.1|ensembl:ENSP00000252136|ensembl:ENSP00000385807|ensembl:ENST00000404751|ensembl:ENSP00000384968|ensembl:ENSG00000099899(gene)|ensembl:ENST00000252136(transcript)|ensembl:ENST00000403707(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0006396"(RNA processing)|go:"GO:0008173"(RNA methyltransferase activity)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR010280("(Uracil-5)-methyltransferase")|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029063|interpro:IPR034262|interpro:IPR035979|mint:Q8IZ69 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:97p8/OfJphcdOJsbap20djvk1nU9606 rogid:/G2YDfinTNhJ+mPHfHOwSsyHQxE9606 rigid:F1SP2bzWuu+sRZ+3ZMLyCqS1TRs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NRG4 uniprotkb:P51617 intact:EBI-1055671|uniprotkb:Q4V765|uniprotkb:Q5VSH9|uniprotkb:Q96AI4|uniprotkb:B2R9P9|uniprotkb:I6L9H7|ensembl:ENSP00000355924 intact:EBI-358664|uniprotkb:Q7Z5V4|uniprotkb:Q96RL2|intact:EBI-28987029|ensembl:ENSP00000358997|uniprotkb:D3DWW4|uniprotkb:D3DWW3|uniprotkb:Q96C06 psi-mi:smyd2_human(display_long)|uniprotkb:KMT3C(gene name synonym)|uniprotkb:HSKM-B(gene name synonym)|uniprotkb:Lysine N-methyltransferase 3C(gene name synonym)|uniprotkb:SMYD2(gene name)|psi-mi:SMYD2(display_short)|uniprotkb:Histone methyltransferase SMYD2(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 2(gene name synonym) psi-mi:irak1_human(display_long)|uniprotkb:IRAK1(gene name)|psi-mi:IRAK1(display_short)|uniprotkb:IRAK(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485032|imex:IM-26985-283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064582.2|ensembl:ENSG00000143499(gene)|ensembl:ENST00000366957(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR044419|mint:Q9NRG4|rcsb pdb:3RIB|rcsb pdb:3S7B|rcsb pdb:3S7D|rcsb pdb:3S7F|rcsb pdb:3S7J|rcsb pdb:3TG4|rcsb pdb:3TG5|rcsb pdb:4O6F|rcsb pdb:4WUY|rcsb pdb:4YND|rcsb pdb:5ARF|rcsb pdb:5ARG|rcsb pdb:5KJK|rcsb pdb:5KJL|rcsb pdb:5KJM|rcsb pdb:5KJN|rcsb pdb:5V3H|rcsb pdb:5WCG|rcsb pdb:6CBX|rcsb pdb:6CBY|rcsb pdb:6MON|rcsb pdb:6N3G|reactome:R-HSA-3214841|reactome:R-HSA-6804760|go:"GO:0034968"(histone lysine methylation)|dip:DIP-50202N go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034134"(toll-like receptor 2 signaling pathway)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035533|interpro:IPR035536|mint:P51617|rcsb pdb:6BFN|ensembl:ENSG00000184216(gene)|ensembl:ENST00000369980(transcript)|go:"GO:0001959"(regulation of cytokine-mediated signaling pathway)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0007254"(JNK cascade)|go:"GO:0007568"(aging)|go:"GO:0010008"(endosome membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|refseq:NP_001020413.1|refseq:NP_001020414.1|refseq:NP_001560.2|reactome:R-HSA-1257604|reactome:R-HSA-166058|reactome:R-HSA-168638|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-6811558|reactome:R-HSA-8986944|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-975110|reactome:R-HSA-975138|reactome:R-HSA-975144|reactome:R-HSA-975155|reactome:R-HSA-975871|ensembl:ENST00000369974|ensembl:ENSP00000358997|ensembl:ENST00000393687|ensembl:ENSP00000377291|ensembl:ENSP00000358991|dip:DIP-397N - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:97p8/OfJphcdOJsbap20djvk1nU9606 rogid:q+oAzeVuuQvO24HkoHx6PKK7XUY9606 rigid:F1SP2bzWuu+sRZ+3ZMLyCqS1TRs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NRG4 uniprotkb:O95757 intact:EBI-1055671|uniprotkb:Q4V765|uniprotkb:Q5VSH9|uniprotkb:Q96AI4|uniprotkb:B2R9P9|uniprotkb:I6L9H7|ensembl:ENSP00000355924 intact:EBI-358652|uniprotkb:Q4W5M5|uniprotkb:Q8IWA2|uniprotkb:A2ICT2|ensembl:ENSP00000296464|ensembl:ENSP00000422482 psi-mi:smyd2_human(display_long)|uniprotkb:KMT3C(gene name synonym)|uniprotkb:HSKM-B(gene name synonym)|uniprotkb:Lysine N-methyltransferase 3C(gene name synonym)|uniprotkb:SMYD2(gene name)|psi-mi:SMYD2(display_short)|uniprotkb:Histone methyltransferase SMYD2(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 2(gene name synonym) psi-mi:hs74l_human(display_long)|uniprotkb:HSPA4L(gene name)|psi-mi:HSPA4L(display_short)|uniprotkb:APG1(gene name synonym)|uniprotkb:OSP94(gene name synonym)|uniprotkb:Osmotic stress protein 94(gene name synonym)|uniprotkb:Heat shock 70-related protein APG-1(gene name synonym)|uniprotkb:Heat-shock protein family A member 4-like protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485032|imex:IM-26985-283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064582.2|ensembl:ENSG00000143499(gene)|ensembl:ENST00000366957(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR044419|mint:Q9NRG4|rcsb pdb:3RIB|rcsb pdb:3S7B|rcsb pdb:3S7D|rcsb pdb:3S7F|rcsb pdb:3S7J|rcsb pdb:3TG4|rcsb pdb:3TG5|rcsb pdb:4O6F|rcsb pdb:4WUY|rcsb pdb:4YND|rcsb pdb:5ARF|rcsb pdb:5ARG|rcsb pdb:5KJK|rcsb pdb:5KJL|rcsb pdb:5KJM|rcsb pdb:5KJN|rcsb pdb:5V3H|rcsb pdb:5WCG|rcsb pdb:6CBX|rcsb pdb:6CBY|rcsb pdb:6MON|rcsb pdb:6N3G|reactome:R-HSA-3214841|reactome:R-HSA-6804760|go:"GO:0034968"(histone lysine methylation)|dip:DIP-50202N go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042708|interpro:IPR043129|mint:O95757|reactome:R-HSA-3371453|refseq:NP_055093.2|refseq:NP_001304310.1|refseq:NP_001304311.1|refseq:NP_001304312.1|go:"GO:0005634"(nucleus)|ensembl:ENSG00000164070(gene)|ensembl:ENST00000296464(transcript)|ensembl:ENST00000508776(transcript)|go:"GO:0005524"(ATP binding) - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:97p8/OfJphcdOJsbap20djvk1nU9606 rogid:6ZoMlI4t4A4u4YsQgrlcwAqjpi49606 rigid:F1SP2bzWuu+sRZ+3ZMLyCqS1TRs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NRG4 uniprotkb:P53597 intact:EBI-1055671|uniprotkb:Q4V765|uniprotkb:Q5VSH9|uniprotkb:Q96AI4|uniprotkb:B2R9P9|uniprotkb:I6L9H7|ensembl:ENSP00000355924 intact:EBI-1237145|uniprotkb:Q9BWB0|uniprotkb:Q9UNP6|ensembl:ENSP00000377446 psi-mi:smyd2_human(display_long)|uniprotkb:KMT3C(gene name synonym)|uniprotkb:HSKM-B(gene name synonym)|uniprotkb:Lysine N-methyltransferase 3C(gene name synonym)|uniprotkb:SMYD2(gene name)|psi-mi:SMYD2(display_short)|uniprotkb:Histone methyltransferase SMYD2(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 2(gene name synonym) psi-mi:suca_human(display_long)|uniprotkb:SUCLG1(gene name)|psi-mi:SUCLG1(display_short)|uniprotkb:Succinyl-CoA synthetase subunit alpha(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485032|imex:IM-26985-283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064582.2|ensembl:ENSG00000143499(gene)|ensembl:ENST00000366957(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR044419|mint:Q9NRG4|rcsb pdb:3RIB|rcsb pdb:3S7B|rcsb pdb:3S7D|rcsb pdb:3S7F|rcsb pdb:3S7J|rcsb pdb:3TG4|rcsb pdb:3TG5|rcsb pdb:4O6F|rcsb pdb:4WUY|rcsb pdb:4YND|rcsb pdb:5ARF|rcsb pdb:5ARG|rcsb pdb:5KJK|rcsb pdb:5KJL|rcsb pdb:5KJM|rcsb pdb:5KJN|rcsb pdb:5V3H|rcsb pdb:5WCG|rcsb pdb:6CBX|rcsb pdb:6CBY|rcsb pdb:6MON|rcsb pdb:6N3G|reactome:R-HSA-3214841|reactome:R-HSA-6804760|go:"GO:0034968"(histone lysine methylation)|dip:DIP-50202N refseq:NP_003840.2|ensembl:ENSG00000163541(gene)|ensembl:ENST00000393868(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004775"("succinate-CoA ligase (ADP-forming) activity")|go:"GO:0004776"("succinate-CoA ligase (GDP-forming) activity")|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0009361"("succinate-CoA ligase complex (ADP-forming)")|interpro:IPR003781(CoA-binding)|interpro:IPR005810(Succinyl-CoA ligase, alpha subunit)|interpro:IPR005811(ATP-citrate lyase/succinyl-CoA ligase)|interpro:IPR016102(Succinyl-CoA synthetase-like)|interpro:IPR017440(ATP-citrate lyase/succinyl-CoA ligase, active site)|interpro:IPR033847|interpro:IPR036291|mint:P53597|rcsb pdb:6G4Q|rcsb pdb:6WCV|reactome:R-HSA-71403 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:97p8/OfJphcdOJsbap20djvk1nU9606 rogid:fti5qbvs9ndhRyZyoPEuTxMpEgo9606 rigid:F1SP2bzWuu+sRZ+3ZMLyCqS1TRs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NRG4 uniprotkb:Q13257 intact:EBI-1055671|uniprotkb:Q4V765|uniprotkb:Q5VSH9|uniprotkb:Q96AI4|uniprotkb:B2R9P9|uniprotkb:I6L9H7|ensembl:ENSP00000355924 intact:EBI-78203|intact:EBI-28969404|ensembl:ENSP00000296509|uniprotkb:Q53F56|uniprotkb:Q548X9|uniprotkb:Q6IRW7|uniprotkb:Q8IZX3 psi-mi:smyd2_human(display_long)|uniprotkb:KMT3C(gene name synonym)|uniprotkb:HSKM-B(gene name synonym)|uniprotkb:Lysine N-methyltransferase 3C(gene name synonym)|uniprotkb:SMYD2(gene name)|psi-mi:SMYD2(display_short)|uniprotkb:Histone methyltransferase SMYD2(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 2(gene name synonym) psi-mi:md2l1_human(display_long)|uniprotkb:MAD2L1(gene name)|psi-mi:MAD2L1(display_short)|uniprotkb:MAD2(gene name synonym)|uniprotkb:Mitotic arrest deficient 2-like protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485032|imex:IM-26985-283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064582.2|ensembl:ENSG00000143499(gene)|ensembl:ENST00000366957(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR044419|mint:Q9NRG4|rcsb pdb:3RIB|rcsb pdb:3S7B|rcsb pdb:3S7D|rcsb pdb:3S7F|rcsb pdb:3S7J|rcsb pdb:3TG4|rcsb pdb:3TG5|rcsb pdb:4O6F|rcsb pdb:4WUY|rcsb pdb:4YND|rcsb pdb:5ARF|rcsb pdb:5ARG|rcsb pdb:5KJK|rcsb pdb:5KJL|rcsb pdb:5KJM|rcsb pdb:5KJN|rcsb pdb:5V3H|rcsb pdb:5WCG|rcsb pdb:6CBX|rcsb pdb:6CBY|rcsb pdb:6MON|rcsb pdb:6N3G|reactome:R-HSA-3214841|reactome:R-HSA-6804760|go:"GO:0034968"(histone lysine methylation)|dip:DIP-50202N ensembl:ENSG00000164109(gene)|ensembl:ENST00000296509(transcript)|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044615"(nuclear pore nuclear basket)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090267"(positive regulation of mitotic cell cycle spindle assembly checkpoint)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003511(DNA-binding HORMA)|interpro:IPR036570|mint:Q13257|rcsb pdb:1DUJ|rcsb pdb:1GO4|rcsb pdb:1S2H|rcsb pdb:1KLQ|rcsb pdb:2QYF|rcsb pdb:2V64|rcsb pdb:2VFX|rcsb pdb:3GMH|rcsb pdb:5KHU|rcsb pdb:5LCW|rcsb pdb:6F0X|rcsb pdb:6TLJ|reactome:R-HSA-141405|reactome:R-HSA-141430|reactome:R-HSA-141444|reactome:R-HSA-174184|reactome:R-HSA-176409|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|ensembl:ENSP00000296509|ensembl:ENST00000333047|ensembl:ENSP00000332295|refseq:NP_002349.1|dip:DIP-29653N - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:97p8/OfJphcdOJsbap20djvk1nU9606 rogid:FyL1tmJllOZ4gQvwWb96aV9PMFw9606 rigid:F1SP2bzWuu+sRZ+3ZMLyCqS1TRs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NRG4 uniprotkb:Q9Y5Y2 intact:EBI-1055671|uniprotkb:Q4V765|uniprotkb:Q5VSH9|uniprotkb:Q96AI4|uniprotkb:B2R9P9|uniprotkb:I6L9H7|ensembl:ENSP00000355924 intact:EBI-1048886|uniprotkb:Q9NWB2|uniprotkb:D3DU80|ensembl:ENSP00000262302 psi-mi:smyd2_human(display_long)|uniprotkb:KMT3C(gene name synonym)|uniprotkb:HSKM-B(gene name synonym)|uniprotkb:Lysine N-methyltransferase 3C(gene name synonym)|uniprotkb:SMYD2(gene name)|psi-mi:SMYD2(display_short)|uniprotkb:Histone methyltransferase SMYD2(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 2(gene name synonym) psi-mi:nubp2_human(display_long)|uniprotkb:Nucleotide-binding protein 2(gene name synonym)|uniprotkb:NUBP2(gene name)|psi-mi:NUBP2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485032|imex:IM-26985-283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064582.2|ensembl:ENSG00000143499(gene)|ensembl:ENST00000366957(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR044419|mint:Q9NRG4|rcsb pdb:3RIB|rcsb pdb:3S7B|rcsb pdb:3S7D|rcsb pdb:3S7F|rcsb pdb:3S7J|rcsb pdb:3TG4|rcsb pdb:3TG5|rcsb pdb:4O6F|rcsb pdb:4WUY|rcsb pdb:4YND|rcsb pdb:5ARF|rcsb pdb:5ARG|rcsb pdb:5KJK|rcsb pdb:5KJL|rcsb pdb:5KJM|rcsb pdb:5KJN|rcsb pdb:5V3H|rcsb pdb:5WCG|rcsb pdb:6CBX|rcsb pdb:6CBY|rcsb pdb:6MON|rcsb pdb:6N3G|reactome:R-HSA-3214841|reactome:R-HSA-6804760|go:"GO:0034968"(histone lysine methylation)|dip:DIP-50202N refseq:NP_001271430.1|refseq:NP_036357.1|ensembl:ENSG00000095906(gene)|ensembl:ENST00000262302(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030030"(cell projection organization)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0046872"(metal ion binding)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR000808(Mrp, conserved site)|interpro:IPR019591|interpro:IPR027417|interpro:IPR028600|interpro:IPR033756|mint:Q9Y5Y2|reactome:R-HSA-2564830 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:97p8/OfJphcdOJsbap20djvk1nU9606 rogid:DKKt1Lpqk/vwGbwhYDXv3Bgtqdc9606 rigid:F1SP2bzWuu+sRZ+3ZMLyCqS1TRs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NRG4 uniprotkb:P54619 intact:EBI-1055671|uniprotkb:Q4V765|uniprotkb:Q5VSH9|uniprotkb:Q96AI4|uniprotkb:B2R9P9|uniprotkb:I6L9H7|ensembl:ENSP00000355924 intact:EBI-1181439|ensembl:ENSP00000447433|uniprotkb:B4DDT7|uniprotkb:Q8N7V9 psi-mi:smyd2_human(display_long)|uniprotkb:KMT3C(gene name synonym)|uniprotkb:HSKM-B(gene name synonym)|uniprotkb:Lysine N-methyltransferase 3C(gene name synonym)|uniprotkb:SMYD2(gene name)|psi-mi:SMYD2(display_short)|uniprotkb:Histone methyltransferase SMYD2(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 2(gene name synonym) psi-mi:aakg1_human(display_long)|uniprotkb:PRKAG1(gene name)|psi-mi:PRKAG1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485032|imex:IM-26985-283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064582.2|ensembl:ENSG00000143499(gene)|ensembl:ENST00000366957(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR044419|mint:Q9NRG4|rcsb pdb:3RIB|rcsb pdb:3S7B|rcsb pdb:3S7D|rcsb pdb:3S7F|rcsb pdb:3S7J|rcsb pdb:3TG4|rcsb pdb:3TG5|rcsb pdb:4O6F|rcsb pdb:4WUY|rcsb pdb:4YND|rcsb pdb:5ARF|rcsb pdb:5ARG|rcsb pdb:5KJK|rcsb pdb:5KJL|rcsb pdb:5KJM|rcsb pdb:5KJN|rcsb pdb:5V3H|rcsb pdb:5WCG|rcsb pdb:6CBX|rcsb pdb:6CBY|rcsb pdb:6MON|rcsb pdb:6N3G|reactome:R-HSA-3214841|reactome:R-HSA-6804760|go:"GO:0034968"(histone lysine methylation)|dip:DIP-50202N refseq:NP_001193638.1|refseq:NP_001193639.1|refseq:NP_002724.1|refseq:XP_011536864.1|reactome:R-HSA-9619483|reactome:R-HSA-9613354|ensembl:ENSG00000181929(gene)|ensembl:ENST00000548065(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004691"(cAMP-dependent protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008603"(cAMP-dependent protein kinase regulator activity)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031588"(nucleotide-activated protein kinase complex)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0043531"(ADP binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051170"(import into nucleus)|go:"GO:0071900"(regulation of protein serine/threonine kinase activity)|interpro:IPR000644(Cystathionine beta-synthase, core)|interpro:IPR039166|mint:P54619|rcsb pdb:2UV4|rcsb pdb:2UV5|rcsb pdb:2UV6|rcsb pdb:2UV7|rcsb pdb:4CFE|rcsb pdb:4CFF|rcsb pdb:4RER|rcsb pdb:4REW|rcsb pdb:4ZHX|rcsb pdb:5EZV|rcsb pdb:5ISO|rcsb pdb:6B1U|rcsb pdb:6B2E|rcsb pdb:6C9F|rcsb pdb:6C9G|rcsb pdb:6C9H|rcsb pdb:6C9J|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|refseq:XP_006719562.1|dip:DIP-39974N - - comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:97p8/OfJphcdOJsbap20djvk1nU9606 rogid:JNBzPdCbcgr37RKb2sk6yVL+7649606 rigid:F1SP2bzWuu+sRZ+3ZMLyCqS1TRs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NRG4 uniprotkb:Q8TE76 intact:EBI-1055671|uniprotkb:Q4V765|uniprotkb:Q5VSH9|uniprotkb:Q96AI4|uniprotkb:B2R9P9|uniprotkb:I6L9H7|ensembl:ENSP00000355924 intact:EBI-3940432|uniprotkb:Q5JUK7|uniprotkb:Q96MZ2|uniprotkb:Q9HAI7|intact:EBI-28969055|ensembl:ENSP00000347821|uniprotkb:A1YR23|uniprotkb:A1YR24|uniprotkb:H7BXF1 psi-mi:smyd2_human(display_long)|uniprotkb:KMT3C(gene name synonym)|uniprotkb:HSKM-B(gene name synonym)|uniprotkb:Lysine N-methyltransferase 3C(gene name synonym)|uniprotkb:SMYD2(gene name)|psi-mi:SMYD2(display_short)|uniprotkb:Histone methyltransferase SMYD2(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 2(gene name synonym) psi-mi:morc4_human(display_long)|uniprotkb:MORC4(gene name)|psi-mi:MORC4(display_short)|uniprotkb:ZCWCC2(gene name synonym)|uniprotkb:Zinc finger CW-type coiled-coil domain protein 2(gene name synonym)|uniprotkb:ZCW4(gene name synonym)|uniprotkb:Zinc finger CW-type domain protein 4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485032|imex:IM-26985-283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064582.2|ensembl:ENSG00000143499(gene)|ensembl:ENST00000366957(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR044419|mint:Q9NRG4|rcsb pdb:3RIB|rcsb pdb:3S7B|rcsb pdb:3S7D|rcsb pdb:3S7F|rcsb pdb:3S7J|rcsb pdb:3TG4|rcsb pdb:3TG5|rcsb pdb:4O6F|rcsb pdb:4WUY|rcsb pdb:4YND|rcsb pdb:5ARF|rcsb pdb:5ARG|rcsb pdb:5KJK|rcsb pdb:5KJL|rcsb pdb:5KJM|rcsb pdb:5KJN|rcsb pdb:5V3H|rcsb pdb:5WCG|rcsb pdb:6CBX|rcsb pdb:6CBY|rcsb pdb:6MON|rcsb pdb:6N3G|reactome:R-HSA-3214841|reactome:R-HSA-6804760|go:"GO:0034968"(histone lysine methylation)|dip:DIP-50202N ensembl:ENST00000255495|ensembl:ENSP00000255495|ensembl:ENSP00000347821|ensembl:ENSG00000133131(gene)|ensembl:ENST00000355610(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|interpro:IPR011124(Zinc finger, CW-type)|interpro:IPR036890|interpro:IPR041006|mint:Q8TE76|rcsb pdb:7K7T|refseq:NP_078933.3|refseq:NP_001078823.1 - - comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:97p8/OfJphcdOJsbap20djvk1nU9606 rogid:4ZXYEyXqgZ18LMwuAgPTsqRtPgw9606 rigid:F1SP2bzWuu+sRZ+3ZMLyCqS1TRs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NRG4 uniprotkb:P20290 intact:EBI-1055671|uniprotkb:Q4V765|uniprotkb:Q5VSH9|uniprotkb:Q96AI4|uniprotkb:B2R9P9|uniprotkb:I6L9H7|ensembl:ENSP00000355924 intact:EBI-1054687|uniprotkb:Q13893|uniprotkb:Q76M56|uniprotkb:A8K510|ensembl:ENSP00000369965 psi-mi:smyd2_human(display_long)|uniprotkb:KMT3C(gene name synonym)|uniprotkb:HSKM-B(gene name synonym)|uniprotkb:Lysine N-methyltransferase 3C(gene name synonym)|uniprotkb:SMYD2(gene name)|psi-mi:SMYD2(display_short)|uniprotkb:Histone methyltransferase SMYD2(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 2(gene name synonym) psi-mi:btf3_human(display_long)|uniprotkb:RNA polymerase B transcription factor 3(gene name synonym)|uniprotkb:BTF3(gene name)|psi-mi:BTF3(display_short)|uniprotkb:NACB(gene name synonym)|uniprotkb:OK/SW-cl.8(orf name)|uniprotkb:Nascent polypeptide-associated complex subunit beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485032|imex:IM-26985-283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064582.2|ensembl:ENSG00000143499(gene)|ensembl:ENST00000366957(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR044419|mint:Q9NRG4|rcsb pdb:3RIB|rcsb pdb:3S7B|rcsb pdb:3S7D|rcsb pdb:3S7F|rcsb pdb:3S7J|rcsb pdb:3TG4|rcsb pdb:3TG5|rcsb pdb:4O6F|rcsb pdb:4WUY|rcsb pdb:4YND|rcsb pdb:5ARF|rcsb pdb:5ARG|rcsb pdb:5KJK|rcsb pdb:5KJL|rcsb pdb:5KJM|rcsb pdb:5KJN|rcsb pdb:5V3H|rcsb pdb:5WCG|rcsb pdb:6CBX|rcsb pdb:6CBY|rcsb pdb:6MON|rcsb pdb:6N3G|reactome:R-HSA-3214841|reactome:R-HSA-6804760|go:"GO:0034968"(histone lysine methylation)|dip:DIP-50202N refseq:NP_001032726.1|refseq:NP_001198.2|ensembl:ENSG00000145741(gene)|ensembl:ENST00000380591(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005854"(nascent polypeptide-associated complex)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0015031"(protein transport)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR038187|interpro:IPR039370|mint:P20290|rcsb pdb:3LKX|rcsb pdb:3MCB - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:97p8/OfJphcdOJsbap20djvk1nU9606 rogid:TU7PtK2KVrzmdfaTdWcHloiRZYg9606 rigid:F1SP2bzWuu+sRZ+3ZMLyCqS1TRs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NRG4 uniprotkb:P54646 intact:EBI-1055671|uniprotkb:Q4V765|uniprotkb:Q5VSH9|uniprotkb:Q96AI4|uniprotkb:B2R9P9|uniprotkb:I6L9H7|ensembl:ENSP00000355924 intact:EBI-1383852|uniprotkb:Q9H1E8|uniprotkb:Q9UD43|ensembl:ENSP00000360290 psi-mi:smyd2_human(display_long)|uniprotkb:KMT3C(gene name synonym)|uniprotkb:HSKM-B(gene name synonym)|uniprotkb:Lysine N-methyltransferase 3C(gene name synonym)|uniprotkb:SMYD2(gene name)|psi-mi:SMYD2(display_short)|uniprotkb:Histone methyltransferase SMYD2(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 2(gene name synonym) psi-mi:aapk2_human(display_long)|uniprotkb:PRKAA2(gene name)|psi-mi:PRKAA2(display_short)|uniprotkb:AMPK(gene name synonym)|uniprotkb:AMPK2(gene name synonym)|uniprotkb:Acetyl-CoA carboxylase kinase(gene name synonym)|uniprotkb:Hydroxymethylglutaryl-CoA reductase kinase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485032|imex:IM-26985-283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064582.2|ensembl:ENSG00000143499(gene)|ensembl:ENST00000366957(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR044419|mint:Q9NRG4|rcsb pdb:3RIB|rcsb pdb:3S7B|rcsb pdb:3S7D|rcsb pdb:3S7F|rcsb pdb:3S7J|rcsb pdb:3TG4|rcsb pdb:3TG5|rcsb pdb:4O6F|rcsb pdb:4WUY|rcsb pdb:4YND|rcsb pdb:5ARF|rcsb pdb:5ARG|rcsb pdb:5KJK|rcsb pdb:5KJL|rcsb pdb:5KJM|rcsb pdb:5KJN|rcsb pdb:5V3H|rcsb pdb:5WCG|rcsb pdb:6CBX|rcsb pdb:6CBY|rcsb pdb:6MON|rcsb pdb:6N3G|reactome:R-HSA-3214841|reactome:R-HSA-6804760|go:"GO:0034968"(histone lysine methylation)|dip:DIP-50202N refseq:NP_006243.2|dip:DIP-39796N|go:"GO:0030425"(dendrite)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035174"(histone serine kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035690"|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045821"(positive regulation of glycolytic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0047322"("[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity")|go:"GO:0048511"(rhythmic process)|go:"GO:0050405"([acetyl-CoA carboxylase] kinase activity)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0062028"(regulation of stress granule assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0030424"(axon)|go:"GO:0071380"(cellular response to prostaglandin E stimulus)|go:"GO:0097009"(energy homeostasis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1904428"(negative regulation of tubulin deacetylation)|go:"GO:2000758"(positive regulation of peptidyl-lysine acetylation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR028783|interpro:IPR032270|interpro:IPR039148|mint:P54646|rcsb pdb:2H6D|rcsb pdb:3AQV|rcsb pdb:2LTU|rcsb pdb:2YZA|rcsb pdb:4CFE|rcsb pdb:4CFF|rcsb pdb:4ZHX|rcsb pdb:5EZV|rcsb pdb:5ISO|rcsb pdb:6B1U|rcsb pdb:6B2E|rcsb pdb:6BX6|reactome:R-HSA-1445148|reactome:R-HSA-1632852|reactome:R-HSA-163680|reactome:R-HSA-200425|reactome:R-HSA-2151209|reactome:R-HSA-380972|reactome:R-HSA-5628897|reactome:R-HSA-6804756|reactome:R-HSA-9613354|reactome:R-HSA-9619483|ensembl:ENSG00000162409(gene)|ensembl:ENST00000371244(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004679"(AMP-activated protein kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0008610"(lipid biosynthetic process)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0014850"(response to muscle activity)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016607"(nuclear speck) - - comment:"author score: 30" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:97p8/OfJphcdOJsbap20djvk1nU9606 rogid:2t/qHlT6HwqoLLbMjjbhOaCZ1Ow9606 rigid:F1SP2bzWuu+sRZ+3ZMLyCqS1TRs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NRG4 uniprotkb:P78346 intact:EBI-1055671|uniprotkb:Q4V765|uniprotkb:Q5VSH9|uniprotkb:Q96AI4|uniprotkb:B2R9P9|uniprotkb:I6L9H7|ensembl:ENSP00000355924 intact:EBI-366553|uniprotkb:B2R799|uniprotkb:E9PB02|ensembl:ENSP00000360768 psi-mi:smyd2_human(display_long)|uniprotkb:KMT3C(gene name synonym)|uniprotkb:HSKM-B(gene name synonym)|uniprotkb:Lysine N-methyltransferase 3C(gene name synonym)|uniprotkb:SMYD2(gene name)|psi-mi:SMYD2(display_short)|uniprotkb:Histone methyltransferase SMYD2(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 2(gene name synonym) psi-mi:rpp30_human(display_long)|uniprotkb:RPP30(gene name)|psi-mi:RPP30(display_short)|uniprotkb:RNASEP2(gene name synonym)|uniprotkb:RNase P subunit 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485032|imex:IM-26985-283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064582.2|ensembl:ENSG00000143499(gene)|ensembl:ENST00000366957(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR044419|mint:Q9NRG4|rcsb pdb:3RIB|rcsb pdb:3S7B|rcsb pdb:3S7D|rcsb pdb:3S7F|rcsb pdb:3S7J|rcsb pdb:3TG4|rcsb pdb:3TG5|rcsb pdb:4O6F|rcsb pdb:4WUY|rcsb pdb:4YND|rcsb pdb:5ARF|rcsb pdb:5ARG|rcsb pdb:5KJK|rcsb pdb:5KJL|rcsb pdb:5KJM|rcsb pdb:5KJN|rcsb pdb:5V3H|rcsb pdb:5WCG|rcsb pdb:6CBX|rcsb pdb:6CBY|rcsb pdb:6MON|rcsb pdb:6N3G|reactome:R-HSA-3214841|reactome:R-HSA-6804760|go:"GO:0034968"(histone lysine methylation)|dip:DIP-50202N refseq:NP_001098016.1|refseq:NP_006404.1|refseq:XP_011537422.1|refseq:XP_011537423.1|ensembl:ENSG00000148688(gene)|ensembl:ENST00000371703(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0006364"(rRNA processing)|go:"GO:0008033"(tRNA processing)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR002738(RNase P subunit p30)|interpro:IPR016195(Polymerase and histidinol phosphatase-like)|mint:P78346|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531|reactome:R-HSA-6791226|refseq:XP_016870964.1|refseq:XP_016870966.1 - - comment:"author score: 32" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:97p8/OfJphcdOJsbap20djvk1nU9606 rogid:pRHvUnpzpNHGzYbS+kRiSa0m71E9606 rigid:F1SP2bzWuu+sRZ+3ZMLyCqS1TRs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NRG4 uniprotkb:Q13765 intact:EBI-1055671|uniprotkb:Q4V765|uniprotkb:Q5VSH9|uniprotkb:Q96AI4|uniprotkb:B2R9P9|uniprotkb:I6L9H7|ensembl:ENSP00000355924 intact:EBI-712216|ensembl:ENSP00000349212|ensembl:ENSP00000377469|ensembl:ENSP00000446801|ensembl:ENSP00000447821|ensembl:ENSP00000503345|uniprotkb:Q3KQV4|uniprotkb:Q53A18|uniprotkb:Q53G46|uniprotkb:A8MTN7|uniprotkb:B2R4P8|uniprotkb:F8VU71 psi-mi:smyd2_human(display_long)|uniprotkb:KMT3C(gene name synonym)|uniprotkb:HSKM-B(gene name synonym)|uniprotkb:Lysine N-methyltransferase 3C(gene name synonym)|uniprotkb:SMYD2(gene name)|psi-mi:SMYD2(display_short)|uniprotkb:Histone methyltransferase SMYD2(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 2(gene name synonym) psi-mi:naca_human(display_long)|uniprotkb:Alpha-NAC(gene name synonym)|uniprotkb:NACA(gene name)|psi-mi:NACA(display_short)|uniprotkb:HSD48(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485032|imex:IM-26985-283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064582.2|ensembl:ENSG00000143499(gene)|ensembl:ENST00000366957(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR044419|mint:Q9NRG4|rcsb pdb:3RIB|rcsb pdb:3S7B|rcsb pdb:3S7D|rcsb pdb:3S7F|rcsb pdb:3S7J|rcsb pdb:3TG4|rcsb pdb:3TG5|rcsb pdb:4O6F|rcsb pdb:4WUY|rcsb pdb:4YND|rcsb pdb:5ARF|rcsb pdb:5ARG|rcsb pdb:5KJK|rcsb pdb:5KJL|rcsb pdb:5KJM|rcsb pdb:5KJN|rcsb pdb:5V3H|rcsb pdb:5WCG|rcsb pdb:6CBX|rcsb pdb:6CBY|rcsb pdb:6MON|rcsb pdb:6N3G|reactome:R-HSA-3214841|reactome:R-HSA-6804760|go:"GO:0034968"(histone lysine methylation)|dip:DIP-50202N ensembl:ENSG00000196531(gene)|ensembl:ENST00000356769(transcript)|ensembl:ENST00000393891(transcript)|ensembl:ENST00000546392(transcript)|ensembl:ENST00000552540(transcript)|ensembl:ENST00000678066(transcript)|go:"GO:0003231"(cardiac ventricle development)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005854"(nascent polypeptide-associated complex)|go:"GO:0006412"(translation)|go:"GO:0010664"(negative regulation of striated muscle cell apoptotic process)|go:"GO:0015031"(protein transport)|go:"GO:0042060"(wound healing)|go:"GO:0048633"(positive regulation of skeletal muscle tissue growth)|go:"GO:0048742"(regulation of skeletal muscle fiber development)|go:"GO:0061384"(heart trabecula morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901227"(negative regulation of transcription from RNA polymerase II promoter involved in heart development)|go:"GO:1901228"(positive regulation of transcription from RNA polymerase II promoter involved in heart development)|go:"GO:2000138"(positive regulation of cell proliferation involved in heart morphogenesis)|interpro:IPR002715(Nascent polypeptide-associated complex NAC)|interpro:IPR016641(Nascent polypeptide-associated complex, alpha subunit)|interpro:IPR038187|interpro:IPR044034|mint:Q13765|rcsb pdb:3LKX|rcsb pdb:3MCB|rcsb pdb:3MCE|go:"GO:0043403"(skeletal muscle tissue regeneration)|refseq:NP_001106672.1|refseq:NP_001307122.1|refseq:NP_001307123.1|refseq:NP_005585.1|refseq:NP_001106673.1|refseq:NP_001106674.2|dip:DIP-43878N - - comment:"author score: 34" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:97p8/OfJphcdOJsbap20djvk1nU9606 rogid:l8QKB8mfSwvDDSSObGLQ7i1LgWo9606 rigid:F1SP2bzWuu+sRZ+3ZMLyCqS1TRs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NRG4 uniprotkb:Q8IUF1 intact:EBI-1055671|uniprotkb:Q4V765|uniprotkb:Q5VSH9|uniprotkb:Q96AI4|uniprotkb:B2R9P9|uniprotkb:I6L9H7|ensembl:ENSP00000355924 intact:EBI-359159|uniprotkb:Q0VAN3|ensembl:ENSP00000259199 psi-mi:smyd2_human(display_long)|uniprotkb:KMT3C(gene name synonym)|uniprotkb:HSKM-B(gene name synonym)|uniprotkb:Lysine N-methyltransferase 3C(gene name synonym)|uniprotkb:SMYD2(gene name)|psi-mi:SMYD2(display_short)|uniprotkb:Histone methyltransferase SMYD2(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 2(gene name synonym) psi-mi:cbwd2_human(display_long)|uniprotkb:CBWD2(gene name)|psi-mi:CBWD2(display_short)|uniprotkb:Cobalamin synthase W domain-containing protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485032|imex:IM-26985-283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064582.2|ensembl:ENSG00000143499(gene)|ensembl:ENST00000366957(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR044419|mint:Q9NRG4|rcsb pdb:3RIB|rcsb pdb:3S7B|rcsb pdb:3S7D|rcsb pdb:3S7F|rcsb pdb:3S7J|rcsb pdb:3TG4|rcsb pdb:3TG5|rcsb pdb:4O6F|rcsb pdb:4WUY|rcsb pdb:4YND|rcsb pdb:5ARF|rcsb pdb:5ARG|rcsb pdb:5KJK|rcsb pdb:5KJL|rcsb pdb:5KJM|rcsb pdb:5KJN|rcsb pdb:5V3H|rcsb pdb:5WCG|rcsb pdb:6CBX|rcsb pdb:6CBY|rcsb pdb:6MON|rcsb pdb:6N3G|reactome:R-HSA-3214841|reactome:R-HSA-6804760|go:"GO:0034968"(histone lysine methylation)|dip:DIP-50202N refseq:NP_742000.1|ensembl:ENSG00000136682(gene)|ensembl:ENST00000259199(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|interpro:IPR003495("Cobalamin (vitamin B12) biosynthesis CobW-like")|interpro:IPR011629("Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal")|interpro:IPR027417|interpro:IPR036627|mint:Q8IUF1 - - comment:"author score: 66" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:97p8/OfJphcdOJsbap20djvk1nU9606 rogid:ySchikxhPpEEcH7X5FiA3JOtSHs9606 rigid:F1SP2bzWuu+sRZ+3ZMLyCqS1TRs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NRG4 uniprotkb:Q15185 intact:EBI-1055671|uniprotkb:Q4V765|uniprotkb:Q5VSH9|uniprotkb:Q96AI4|uniprotkb:B2R9P9|uniprotkb:I6L9H7|ensembl:ENSP00000355924 intact:EBI-1049387|uniprotkb:Q8WU70|intact:EBI-9357271|uniprotkb:B4DHP2|uniprotkb:B4DP11|uniprotkb:B4DP21|uniprotkb:A8K7D0|ensembl:ENSP00000262033 psi-mi:smyd2_human(display_long)|uniprotkb:KMT3C(gene name synonym)|uniprotkb:HSKM-B(gene name synonym)|uniprotkb:Lysine N-methyltransferase 3C(gene name synonym)|uniprotkb:SMYD2(gene name)|psi-mi:SMYD2(display_short)|uniprotkb:Histone methyltransferase SMYD2(gene name synonym)|uniprotkb:SET and MYND domain-containing protein 2(gene name synonym) psi-mi:tebp_human(display_long)|uniprotkb:Cytosolic prostaglandin E2 synthase(gene name synonym)|uniprotkb:Telomerase-binding protein p23(gene name synonym)|uniprotkb:Progesterone receptor complex p23(gene name synonym)|uniprotkb:PTGES3(gene name)|psi-mi:PTGES3(display_short)|uniprotkb:P23(gene name synonym)|uniprotkb:TEBP(gene name synonym)|uniprotkb:Hsp90 co-chaperone(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485032|imex:IM-26985-283 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064582.2|ensembl:ENSG00000143499(gene)|ensembl:ENST00000366957(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007507"(heart development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016278"(lysine N-methyltransferase activity)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0018026"(peptidyl-lysine monomethylation)|go:"GO:0018027"(peptidyl-lysine dimethylation)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001214(SET)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR044419|mint:Q9NRG4|rcsb pdb:3RIB|rcsb pdb:3S7B|rcsb pdb:3S7D|rcsb pdb:3S7F|rcsb pdb:3S7J|rcsb pdb:3TG4|rcsb pdb:3TG5|rcsb pdb:4O6F|rcsb pdb:4WUY|rcsb pdb:4YND|rcsb pdb:5ARF|rcsb pdb:5ARG|rcsb pdb:5KJK|rcsb pdb:5KJL|rcsb pdb:5KJM|rcsb pdb:5KJN|rcsb pdb:5V3H|rcsb pdb:5WCG|rcsb pdb:6CBX|rcsb pdb:6CBY|rcsb pdb:6MON|rcsb pdb:6N3G|reactome:R-HSA-3214841|reactome:R-HSA-6804760|go:"GO:0034968"(histone lysine methylation)|dip:DIP-50202N refseq:NP_001269530.1|refseq:NP_001269531.1|refseq:NP_001269532.1|refseq:NP_001269533.1|refseq:NP_001269534.1|refseq:NP_006592.3|dip:DIP-279N|ensembl:ENSG00000110958(gene)|ensembl:ENST00000262033(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0003720"(telomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0006457"(protein folding)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007165"(signal transduction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0019371"(cyclooxygenase pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0043588"(skin development)|go:"GO:0050220"(prostaglandin-E synthase activity)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060430"(lung saccule development)|go:"GO:0070182"(DNA polymerase binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1905323"(telomerase holoenzyme complex assembly)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|mint:Q15185|rcsb pdb:1EJF|reactome:R-HSA-2162123|reactome:R-HSA-3371497|reactome:R-HSA-3371511|reactome:R-HSA-3371568|reactome:R-HSA-8937144|reactome:R-HSA-8939211|reactome:R-HSA-9018519|reactome:R-HSA-9679191|rcsb pdb:1LG0 - - comment:"author score: 90" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:97p8/OfJphcdOJsbap20djvk1nU9606 rogid:6NuM7BPG39XzwqdKBCr74uuumCo9606 rigid:F1SP2bzWuu+sRZ+3ZMLyCqS1TRs false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HB58 uniprotkb:P19784 intact:EBI-721477|uniprotkb:Q53TG2|uniprotkb:Q14976|uniprotkb:Q14977|uniprotkb:Q8WUZ6|uniprotkb:Q9HCT8|ensembl:ENSP00000351488|uniprotkb:B4DVI4|uniprotkb:F5H1M1 intact:EBI-347451|ensembl:ENSP00000262506 psi-mi:sp110_human(display_long)|uniprotkb:Transcriptional coactivator Sp110(gene name synonym)|uniprotkb:Speckled 110 kDa(gene name synonym)|uniprotkb:Interferon-induced protein 41/75(gene name synonym)|uniprotkb:SP110(gene name)|psi-mi:SP110(display_short) psi-mi:csk22_human(display_long)|uniprotkb:CSNK2A2(gene name)|psi-mi:CSNK2A2(display_short)|uniprotkb:CK2A2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485359|imex:IM-26985-287 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171944.1|refseq:NP_004500.3|refseq:NP_536349.2|interpro:IPR004865(Sp100)|interpro:IPR010919(SAND-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR043563|mint:Q9HB58|ensembl:ENSG00000135899(gene)|ensembl:ENST00000358662(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000770(SAND)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type) refseq:NP_001887.1|dip:DIP-318N|ensembl:ENSG00000070770(gene)|ensembl:ENST00000262506(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0097421"(liver regeneration)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:1905818"(regulation of chromosome separation)|go:"GO:2000059"(negative regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P19784|rcsb pdb:3E3B|rcsb pdb:3OFM|rcsb pdb:3U87|rcsb pdb:5M4U|rcsb pdb:5M56|rcsb pdb:5OOI|rcsb pdb:5Y9M|rcsb pdb:5YF9|rcsb pdb:5YWM|rcsb pdb:6HMB|rcsb pdb:6HMC|rcsb pdb:6HMD|rcsb pdb:6HMQ|rcsb pdb:6L20|rcsb pdb:6QY8|rcsb pdb:6QY9|rcsb pdb:6TE2|rcsb pdb:6TEW|rcsb pdb:6TGU|rcsb pdb:7A1B|rcsb pdb:7A1Z|rcsb pdb:7A22|rcsb pdb:7A2H|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:foLtJoiwqgk1Urc34PzLK6PsUO09606 rogid:SIekW2yzNePP9hLKW7OHNFBwNck9606 rigid:o2S/yo9kJTwoADpkH8RetFZXfwk false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HB58 uniprotkb:O14974 intact:EBI-721477|uniprotkb:Q53TG2|uniprotkb:Q14976|uniprotkb:Q14977|uniprotkb:Q8WUZ6|uniprotkb:Q9HCT8|ensembl:ENSP00000351488|uniprotkb:B4DVI4|uniprotkb:F5H1M1 intact:EBI-351726|uniprotkb:Q2NKL4|uniprotkb:Q569H0|uniprotkb:Q86WU3|uniprotkb:Q8NFR6|uniprotkb:Q9BYH0|intact:EBI-28988491|uniprotkb:B4DZ09|uniprotkb:F8VWB4|ensembl:ENSP00000261207|ensembl:ENSP00000389168 psi-mi:sp110_human(display_long)|uniprotkb:Transcriptional coactivator Sp110(gene name synonym)|uniprotkb:Speckled 110 kDa(gene name synonym)|uniprotkb:Interferon-induced protein 41/75(gene name synonym)|uniprotkb:SP110(gene name)|psi-mi:SP110(display_short) psi-mi:mypt1_human(display_long)|uniprotkb:PPP1R12A(gene name)|psi-mi:PPP1R12A(display_short)|uniprotkb:MBS(gene name synonym)|uniprotkb:MYPT1(gene name synonym)|uniprotkb:Myosin phosphatase-targeting subunit 1(gene name synonym)|uniprotkb:Protein phosphatase myosin-binding subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485359|imex:IM-26985-287 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171944.1|refseq:NP_004500.3|refseq:NP_536349.2|interpro:IPR004865(Sp100)|interpro:IPR010919(SAND-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR043563|mint:Q9HB58|ensembl:ENSG00000135899(gene)|ensembl:ENST00000358662(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000770(SAND)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type) refseq:NP_001137357.1|refseq:NP_001137358.1|refseq:NP_002471.1|refseq:NP_001231919.1|refseq:NP_001231921.1|refseq:XP_011536685.1|ensembl:ENSP00000261207|ensembl:ENST00000437004|ensembl:ENSP00000416769|ensembl:ENSP00000389168|ensembl:ENSP00000449514|ensembl:ENST00000550107|ensembl:ENSP00000446855|ensembl:ENST00000546369|dip:DIP-33186N|ensembl:ENSG00000058272(gene)|ensembl:ENST00000261207(transcript)|ensembl:ENST00000450142(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000776"(kinetochore)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007098"(centrosome cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019208"(phosphatase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0031672"(A band)|go:"GO:0035507"(regulation of myosin-light-chain-phosphatase activity)|go:"GO:0035508"(positive regulation of myosin-light-chain-phosphatase activity)|go:"GO:0035690"|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043292"(contractile fiber)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|interpro:IPR002110(Ankyrin)|interpro:IPR017401(Protein phosphatase 1, regulatory subunits 12A/B/C, eukaryote)|interpro:IPR020683|interpro:IPR031775|interpro:IPR036770|mint:O14974|rcsb pdb:2KJY|rcsb pdb:5HUZ|reactome:R-HSA-2565942|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:foLtJoiwqgk1Urc34PzLK6PsUO09606 rogid:Xi5lGskc0tWQCHtbYlgR45ERMSk9606 rigid:o2S/yo9kJTwoADpkH8RetFZXfwk false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HB58 uniprotkb:P13489 intact:EBI-721477|uniprotkb:Q53TG2|uniprotkb:Q14976|uniprotkb:Q14977|uniprotkb:Q8WUZ6|uniprotkb:Q9HCT8|ensembl:ENSP00000351488|uniprotkb:B4DVI4|uniprotkb:F5H1M1 intact:EBI-1237106|uniprotkb:Q8IZK8|uniprotkb:Q96FD7|uniprotkb:Q9BQ80|uniprotkb:Q9UDK6|ensembl:ENSP00000346402|ensembl:ENSP00000348515|ensembl:ENSP00000380729|ensembl:ENSP00000380738|ensembl:ENSP00000380739|ensembl:ENSP00000416589|ensembl:ENSP00000433999|ensembl:ENSP00000435594|ensembl:ENSP00000478664|ensembl:ENSP00000479004|ensembl:ENSP00000479966|ensembl:ENSP00000480036|ensembl:ENSP00000484572|ensembl:ENSP00000487753|ensembl:ENSP00000487940|ensembl:ENSP00000488734 psi-mi:sp110_human(display_long)|uniprotkb:Transcriptional coactivator Sp110(gene name synonym)|uniprotkb:Speckled 110 kDa(gene name synonym)|uniprotkb:Interferon-induced protein 41/75(gene name synonym)|uniprotkb:SP110(gene name)|psi-mi:SP110(display_short) psi-mi:rini_human(display_long)|uniprotkb:RNH1(gene name)|psi-mi:RNH1(display_short)|uniprotkb:PRI(gene name synonym)|uniprotkb:RNH(gene name synonym)|uniprotkb:Ribonuclease/angiogenin inhibitor 1(gene name synonym)|uniprotkb:Placental ribonuclease inhibitor(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485359|imex:IM-26985-287 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171944.1|refseq:NP_004500.3|refseq:NP_536349.2|interpro:IPR004865(Sp100)|interpro:IPR010919(SAND-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR043563|mint:Q9HB58|ensembl:ENSG00000135899(gene)|ensembl:ENST00000358662(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000770(SAND)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type) refseq:NP_002930.2|refseq:NP_976317.1|refseq:NP_976318.1|refseq:NP_976319.1|refseq:NP_976320.1|refseq:NP_976321.1|refseq:NP_976322.1|refseq:NP_976323.1|refseq:XP_011518557.1|refseq:XP_011518559.1|refseq:XP_011518560.1|refseq:XP_011518561.1|refseq:XP_011518562.1|refseq:XP_011518563.1|refseq:XP_011518564.1|refseq:XP_011518565.1|refseq:XP_016873595.1|ensembl:ENST00000619599(transcript)|ensembl:ENST00000621211(transcript)|ensembl:ENST00000632527(transcript)|ensembl:ENST00000632954(transcript)|ensembl:ENST00000633287(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0008428"(ribonuclease inhibitor activity)|go:"GO:0032311"(angiogenin-PRI complex)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR006553(Leucine-rich repeat, cysteine-containing subtype)|interpro:IPR032675|interpro:IPR041302|mint:P13489|rcsb pdb:1A4Y|rcsb pdb:1Z7X|rcsb pdb:2BEX|rcsb pdb:2Q4G|ensembl:ENSG00000023191(gene)|ensembl:ENSG00000276230(gene)|ensembl:ENST00000354420(transcript)|ensembl:ENST00000356187(transcript)|ensembl:ENST00000397604(transcript)|ensembl:ENST00000397614(transcript)|ensembl:ENST00000397615(transcript)|ensembl:ENST00000438658(transcript)|ensembl:ENST00000533410(transcript)|ensembl:ENST00000534797(transcript)|ensembl:ENST00000612988(transcript)|ensembl:ENST00000617351(transcript)|ensembl:ENST00000618184(transcript) - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:foLtJoiwqgk1Urc34PzLK6PsUO09606 rogid:1WMWoYulk8Aj8HYhDcqnauddUFk9606 rigid:o2S/yo9kJTwoADpkH8RetFZXfwk false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HB58 uniprotkb:P67870 intact:EBI-721477|uniprotkb:Q53TG2|uniprotkb:Q14976|uniprotkb:Q14977|uniprotkb:Q8WUZ6|uniprotkb:Q9HCT8|ensembl:ENSP00000351488|uniprotkb:B4DVI4|uniprotkb:F5H1M1 intact:EBI-348169|ensembl:ENSP00000365025|ensembl:ENSP00000365026|ensembl:ENSP00000365042|ensembl:ENSP00000372919|ensembl:ENSP00000372925|ensembl:ENSP00000382980|ensembl:ENSP00000390900|ensembl:ENSP00000391038|ensembl:ENSP00000393756|ensembl:ENSP00000394855|ensembl:ENSP00000395275|ensembl:ENSP00000400188|ensembl:ENSP00000407018|ensembl:ENSP00000407379|ensembl:ENSP00000409510|ensembl:ENSP00000410802|ensembl:ENSP00000411322|ensembl:ENSP00000412520|ensembl:ENSP00000413469|ensembl:ENSP00000415237|ensembl:ENSP00000415303|uniprotkb:P07312|uniprotkb:P13862|uniprotkb:Q4VX47|intact:EBI-3866975|uniprotkb:B0UXA9 psi-mi:sp110_human(display_long)|uniprotkb:Transcriptional coactivator Sp110(gene name synonym)|uniprotkb:Speckled 110 kDa(gene name synonym)|uniprotkb:Interferon-induced protein 41/75(gene name synonym)|uniprotkb:SP110(gene name)|psi-mi:SP110(display_short) psi-mi:csk2b_human(display_long)|uniprotkb:Phosvitin(gene name synonym)|uniprotkb:Protein G5a(gene name synonym)|uniprotkb:CSNK2B(gene name)|psi-mi:CSNK2B(display_short)|uniprotkb:CK2N(gene name synonym)|uniprotkb:G5A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485359|imex:IM-26985-287 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171944.1|refseq:NP_004500.3|refseq:NP_536349.2|interpro:IPR004865(Sp100)|interpro:IPR010919(SAND-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR043563|mint:Q9HB58|ensembl:ENSG00000135899(gene)|ensembl:ENST00000358662(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000770(SAND)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type) ensembl:ENSG00000204435(gene)|ensembl:ENSG00000230700(gene)|ensembl:ENSG00000206406(gene)|ensembl:ENSG00000232960(gene)|ensembl:ENSG00000224398(gene)|ensembl:ENSG00000224774(gene)|ensembl:ENSG00000228875(gene)|ensembl:ENST00000375882(transcript)|ensembl:ENST00000383427(transcript)|ensembl:ENST00000383433(transcript)|ensembl:ENST00000400110(transcript)|ensembl:ENST00000412802(transcript)|ensembl:ENST00000418230(transcript)|ensembl:ENST00000422567(transcript)|ensembl:ENST00000429633(transcript)|ensembl:ENST00000431476(transcript)|ensembl:ENST00000436169(transcript)|ensembl:ENST00000443673(transcript)|ensembl:ENST00000448596(transcript)|ensembl:ENST00000451917(transcript)|ensembl:ENST00000452985(transcript)|ensembl:ENST00000453234(transcript)|ensembl:ENST00000454382(transcript)|ensembl:ENST00000454511(transcript)|ensembl:ENST00000455161(transcript)|ensembl:ENST00000458330(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0005956"(protein kinase CK2 complex)|go:"GO:0007165"(signal transduction)|ensembl:ENST00000375865(transcript)|ensembl:ENST00000375866(transcript)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016363"(nuclear matrix)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032927"(positive regulation of activin receptor signaling pathway)|go:"GO:0033211"(adiponectin-activated signaling pathway)|go:"GO:0033574"(response to testosterone)|go:"GO:0034622"|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0051101"(regulation of DNA binding)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0080163"(regulation of protein serine/threonine phosphatase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000704(Casein kinase II, regulatory subunit)|interpro:IPR016149(Casein kinase II, regulatory subunit, alpha-helical)|interpro:IPR035991|mint:P67870|rcsb pdb:1DS5|rcsb pdb:1JWH|go:"GO:0008134"(transcription factor binding)|rcsb pdb:1QF8|rcsb pdb:3EED|rcsb pdb:4DGL|rcsb pdb:4MD7|rcsb pdb:4MD8|rcsb pdb:4MD9|rcsb pdb:4NH1|reactome:R-HSA-1483191|reactome:R-HSA-201688|reactome:R-HSA-2514853|reactome:R-HSA-445144|reactome:R-HSA-6798695|reactome:R-HSA-6804756|reactome:R-HSA-6814122|reactome:R-HSA-8932339|reactome:R-HSA-8934903|reactome:R-HSA-8939243|reactome:R-HSA-8948751|rcsb pdb:6Q38|refseq:NP_001311.3|refseq:NP_001269314.1|dip:DIP-131N - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:foLtJoiwqgk1Urc34PzLK6PsUO09606 rogid:ZTHJjCqHg2dE7B+WoSU28VSMuPg9606 rigid:o2S/yo9kJTwoADpkH8RetFZXfwk false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HB58 uniprotkb:Q9UNE7 intact:EBI-721477|uniprotkb:Q53TG2|uniprotkb:Q14976|uniprotkb:Q14977|uniprotkb:Q8WUZ6|uniprotkb:Q9HCT8|ensembl:ENSP00000351488|uniprotkb:B4DVI4|uniprotkb:F5H1M1 intact:EBI-357085|uniprotkb:O60526|uniprotkb:Q969U2|uniprotkb:Q9HBT1|uniprotkb:A2IDB9|ensembl:ENSP00000219548 psi-mi:sp110_human(display_long)|uniprotkb:Transcriptional coactivator Sp110(gene name synonym)|uniprotkb:Speckled 110 kDa(gene name synonym)|uniprotkb:Interferon-induced protein 41/75(gene name synonym)|uniprotkb:SP110(gene name)|psi-mi:SP110(display_short) psi-mi:chip_human(display_long)|uniprotkb:CHIP(gene name synonym)|uniprotkb:STUB1(gene name)|psi-mi:STUB1(display_short)|uniprotkb:PP1131(orf name)|uniprotkb:Carboxy terminus of Hsp70-interacting protein(gene name synonym)|uniprotkb:STIP1 homology and U box-containing protein 1(gene name synonym)|uniprotkb:CLL-associated antigen KW-8(gene name synonym)|uniprotkb:Antigen NY-CO-7(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CHIP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485359|imex:IM-26985-287 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171944.1|refseq:NP_004500.3|refseq:NP_536349.2|interpro:IPR004865(Sp100)|interpro:IPR010919(SAND-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR043563|mint:Q9HB58|ensembl:ENSG00000135899(gene)|ensembl:ENST00000358662(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000770(SAND)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type) dip:DIP-29752N|refseq:NP_005852.2|refseq:NP_001280126.1|ensembl:ENSG00000103266(gene)|ensembl:ENST00000219548(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0002931"(response to ischemia)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030911"(TPR domain binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031371"(ubiquitin conjugating enzyme complex)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031943"(regulation of glucocorticoid metabolic process)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034450"(ubiquitin-ubiquitin ligase activity)|go:"GO:0034605"(cellular response to heat)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0042405"(nuclear inclusion body)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046332"(SMAD binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0051604"(protein maturation)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0030579"(ubiquitin-dependent SMAD protein catabolic process)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070534"(protein K63-linked ubiquitination)|go:"GO:0071218"(cellular response to misfolded protein)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0090035"(positive regulation of chaperone-mediated protein complex assembly)|go:"GO:0101031"(chaperone complex)|interpro:IPR003613(U box)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019734|interpro:IPR041312|mint:Q9UNE7|rcsb pdb:4KBQ|rcsb pdb:6EFK|rcsb pdb:6NSV|reactome:R-HSA-2173788|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-8863795|reactome:R-HSA-8939902|reactome:R-HSA-8948751|reactome:R-HSA-983168 - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:foLtJoiwqgk1Urc34PzLK6PsUO09606 rogid:h4QyIM0TptgkQppPUgiKn68XjP49606 rigid:o2S/yo9kJTwoADpkH8RetFZXfwk false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HB58 uniprotkb:P62136 intact:EBI-721477|uniprotkb:Q53TG2|uniprotkb:Q14976|uniprotkb:Q14977|uniprotkb:Q8WUZ6|uniprotkb:Q9HCT8|ensembl:ENSP00000351488|uniprotkb:B4DVI4|uniprotkb:F5H1M1 intact:EBI-357253|uniprotkb:P08129|uniprotkb:P20653|uniprotkb:P22802|uniprotkb:B2R908|intact:EBI-2623163|uniprotkb:Q07161|intact:EBI-2556927|uniprotkb:A6NNR3|ensembl:ENSP00000365936 psi-mi:sp110_human(display_long)|uniprotkb:Transcriptional coactivator Sp110(gene name synonym)|uniprotkb:Speckled 110 kDa(gene name synonym)|uniprotkb:Interferon-induced protein 41/75(gene name synonym)|uniprotkb:SP110(gene name)|psi-mi:SP110(display_short) psi-mi:pp1a_human(display_long)|uniprotkb:PPP1CA(gene name)|psi-mi:PPP1CA(display_short)|uniprotkb:PPP1A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485359|imex:IM-26985-287 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171944.1|refseq:NP_004500.3|refseq:NP_536349.2|interpro:IPR004865(Sp100)|interpro:IPR010919(SAND-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR043563|mint:Q9HB58|ensembl:ENSG00000135899(gene)|ensembl:ENST00000358662(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000770(SAND)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type) refseq:NP_001008709.1|refseq:NP_002699.1|refseq:NP_996756.1|dip:DIP-221N|dip:DIP-38195N|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0036496"(regulation of translational initiation by eIF2 alpha dephosphorylation)|go:"GO:0042587"(glycogen granule)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0051301"(cell division)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904886"(beta-catenin destruction complex disassembly)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|interpro:IPR037979|mint:P62136|rcsb pdb:3E7A|rcsb pdb:3E7B|rcsb pdb:3EGG|rcsb pdb:3EGH|rcsb pdb:3HVQ|rcsb pdb:3N5U|rcsb pdb:3V4Y|rcsb pdb:4G9J|rcsb pdb:4MOV|rcsb pdb:4MOY|rcsb pdb:4MP0|rcsb pdb:4XPN|rcsb pdb:5IOH|rcsb pdb:6ALZ|rcsb pdb:6CZO|rcsb pdb:6DCX|rcsb pdb:6DNO|rcsb pdb:6G0I|rcsb pdb:6G0J|rcsb pdb:6GHM|rcsb pdb:6OBN|rcsb pdb:6OBP|rcsb pdb:6OBQ|rcsb pdb:6OBR|rcsb pdb:6OBS|rcsb pdb:6OBU|rcsb pdb:6ZEE|rcsb pdb:6ZEF|rcsb pdb:6ZEG|rcsb pdb:6ZEH|rcsb pdb:6ZEI|rcsb pdb:6ZEJ|rcsb pdb:6ZK6|reactome:R-HSA-163560|reactome:R-HSA-180024|reactome:R-HSA-2173788|reactome:R-HSA-400253|go:"GO:0098793"(presynapse)|ensembl:ENSG00000172531(gene)|ensembl:ENST00000376745(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0030324"(lung development) - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:foLtJoiwqgk1Urc34PzLK6PsUO09606 rogid:IMypaKng+5AECbCd3N72pgzUlxQ9606 rigid:o2S/yo9kJTwoADpkH8RetFZXfwk false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HB58 uniprotkb:O15355 intact:EBI-721477|uniprotkb:Q53TG2|uniprotkb:Q14976|uniprotkb:Q14977|uniprotkb:Q8WUZ6|uniprotkb:Q9HCT8|ensembl:ENSP00000351488|uniprotkb:B4DVI4|uniprotkb:F5H1M1 intact:EBI-725702|ensembl:ENSP00000342778 psi-mi:sp110_human(display_long)|uniprotkb:Transcriptional coactivator Sp110(gene name synonym)|uniprotkb:Speckled 110 kDa(gene name synonym)|uniprotkb:Interferon-induced protein 41/75(gene name synonym)|uniprotkb:SP110(gene name)|psi-mi:SP110(display_short) psi-mi:ppm1g_human(display_long)|uniprotkb:Protein phosphatase 2C isoform gamma(gene name synonym)|uniprotkb:Protein phosphatase magnesium-dependent 1 gamma(gene name synonym)|uniprotkb:Protein phosphatase 1C(gene name synonym)|uniprotkb:PPM1G(gene name)|psi-mi:PPM1G(display_short)|uniprotkb:PPM1C(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485359|imex:IM-26985-287 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171944.1|refseq:NP_004500.3|refseq:NP_536349.2|interpro:IPR004865(Sp100)|interpro:IPR010919(SAND-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR043563|mint:Q9HB58|ensembl:ENSG00000135899(gene)|ensembl:ENST00000358662(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000770(SAND)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type) refseq:NP_817092.1|ensembl:ENST00000344034(transcript)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006470"(protein dephosphorylation)|ensembl:ENSG00000115241(gene)|go:"GO:0016020"(membrane)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000222(Protein phosphatase 2C, manganese/magnesium aspartate binding site)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:O15355|dip:DIP-29404N - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:foLtJoiwqgk1Urc34PzLK6PsUO09606 rogid:j9ut2f7QHVyOtsLuYJ8e2XOP3HE9606 rigid:o2S/yo9kJTwoADpkH8RetFZXfwk false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HB58 uniprotkb:Q96EB6 intact:EBI-721477|uniprotkb:Q53TG2|uniprotkb:Q14976|uniprotkb:Q14977|uniprotkb:Q8WUZ6|uniprotkb:Q9HCT8|ensembl:ENSP00000351488|uniprotkb:B4DVI4|uniprotkb:F5H1M1 intact:EBI-1802965|uniprotkb:Q2XNF6|uniprotkb:Q5JVQ0|uniprotkb:Q9GZR9|uniprotkb:Q9Y6F0|ensembl:ENSP00000212015 psi-mi:sp110_human(display_long)|uniprotkb:Transcriptional coactivator Sp110(gene name synonym)|uniprotkb:Speckled 110 kDa(gene name synonym)|uniprotkb:Interferon-induced protein 41/75(gene name synonym)|uniprotkb:SP110(gene name)|psi-mi:SP110(display_short) psi-mi:sir1_human(display_long)|uniprotkb:NAD-dependent protein deacylase sirtuin-1(gene name synonym)|uniprotkb:SIRT1(gene name)|psi-mi:SIRT1(display_short)|uniprotkb:SIR2L1(gene name synonym)|uniprotkb:SIR2-like protein 1(gene name synonym)|uniprotkb:Regulatory protein SIR2 homolog 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485359|imex:IM-26985-287 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171944.1|refseq:NP_004500.3|refseq:NP_536349.2|interpro:IPR004865(Sp100)|interpro:IPR010919(SAND-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR043563|mint:Q9HB58|ensembl:ENSG00000135899(gene)|ensembl:ENST00000358662(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000770(SAND)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type) refseq:NP_001135970.1|refseq:NP_036370.2|refseq:NP_001300978.1|dip:DIP-29757N|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:2000774"(positive regulation of cellular senescence)|interpro:IPR003000(NAD-dependent histone deacetylase, silent information regulator Sir2)|interpro:IPR026590|interpro:IPR026591|interpro:IPR029035|mint:Q96EB6|rcsb pdb:4I5I|rcsb pdb:4IF6|rcsb pdb:4IG9|rcsb pdb:4KXQ|rcsb pdb:4ZZH|rcsb pdb:4ZZI|rcsb pdb:4ZZJ|rcsb pdb:5BTR|reactome:R-HSA-3371453|reactome:R-HSA-400253|reactome:R-HSA-427359|reactome:R-HSA-9617629|reactome:R-HSA-9707616|go:"GO:2000757"(negative regulation of peptidyl-lysine acetylation)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0006346"(DNA methylation-dependent heterochromatin assembly)|go:"GO:0006476"(protein deacetylation)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0007517"(muscle organ development)|go:"GO:0007569"(cell aging)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010883"(regulation of lipid storage)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0005739"(mitochondrion)|ensembl:ENSG00000096717(gene)|ensembl:ENST00000212015(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000731"(DNA synthesis involved in DNA repair)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001525"(angiogenesis)|go:"GO:0001542"(ovulation from ovarian follicle)|go:"GO:0001650"(fibrillar center)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002039"(p53 binding)|go:"GO:0002821"(positive regulation of adaptive immune response)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0000720"(pyrimidine dimer repair by nucleotide-excision repair)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016575"(histone deacetylation)|go:"GO:0016605"(PML body)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0017136"(NAD-dependent histone deacetylase activity)|go:"GO:0018394"(peptidyl-lysine acetylation)|go:"GO:0019213"(deacetylase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031393"(negative regulation of prostaglandin biosynthetic process)|go:"GO:0031507"(heterochromatin assembly)|go:"GO:0031648"(protein destabilization)|go:"GO:0032007"(negative regulation of TOR signaling)|go:"GO:0032071"(regulation of endodeoxyribonuclease activity)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032868"(response to insulin)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034391"(regulation of smooth muscle cell apoptotic process)|go:"GO:0034979"(NAD-dependent protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0035356"(cellular triglyceride homeostasis)|go:"GO:0035358"(regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042393"(histone binding)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042595"(behavioral response to starvation)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043398"(HLH domain binding)|go:"GO:0043425"(bHLH transcription factor binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0045348"(positive regulation of MHC class II biosynthetic process)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046872"(metal ion binding)|go:"GO:0046969"("NAD-dependent histone deacetylase activity (H3-K9 specific)")|go:"GO:0050872"(white fat cell differentiation)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0051152"(positive regulation of smooth muscle cell differentiation)|go:"GO:0051574"(positive regulation of histone H3-K9 methylation)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0055089"(fatty acid homeostasis)|go:"GO:0060766"(negative regulation of androgen receptor signaling pathway)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070403"(NAD+ binding)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0070857"(regulation of bile acid biosynthetic process)|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0044321"(response to leptin)|go:"GO:0071441"(negative regulation of histone H3-K14 acetylation)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071900"(regulation of protein serine/threonine kinase activity)|go:"GO:0090335"(regulation of brown fat cell differentiation)|go:"GO:0090400"(stress-induced premature senescence)|go:"GO:0106230"(protein depropionylation)|go:"GO:0106231"(protein-propionyllysine depropionylase activity)|go:"GO:1900034"(regulation of cellular response to heat)|go:"GO:1900113"(negative regulation of histone H3-K9 trimethylation)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901984"(negative regulation of protein acetylation)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904179"(positive regulation of adipose tissue development)|go:"GO:1990254"(keratin filament binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000111"(positive regulation of macrophage apoptotic process)|go:"GO:2000480"(negative regulation of cAMP-dependent protein kinase activity)|go:"GO:2000481"(positive regulation of cAMP-dependent protein kinase activity)|go:"GO:2000619"(negative regulation of histone H4-K16 acetylation)|go:"GO:2000655"(negative regulation of cellular response to testosterone stimulus)|go:"GO:0071356"(cellular response to tumor necrosis factor) - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:foLtJoiwqgk1Urc34PzLK6PsUO09606 rogid:h3zVepuhRhzlINCluVuAn71Btjc9606 rigid:o2S/yo9kJTwoADpkH8RetFZXfwk false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HB58 uniprotkb:Q9C0C9 intact:EBI-721477|uniprotkb:Q53TG2|uniprotkb:Q14976|uniprotkb:Q14977|uniprotkb:Q8WUZ6|uniprotkb:Q9HCT8|ensembl:ENSP00000351488|uniprotkb:B4DVI4|uniprotkb:F5H1M1 intact:EBI-2339946|uniprotkb:Q8N425|uniprotkb:Q9H9B2|uniprotkb:Q6PIZ2|uniprotkb:Q9H7E4|uniprotkb:Q8TBN1|uniprotkb:A6NDU5|uniprotkb:Q9BSW1|uniprotkb:Q69YP4|uniprotkb:Q86UA4|uniprotkb:Q9H6E6|ensembl:ENSP00000323687 psi-mi:sp110_human(display_long)|uniprotkb:Transcriptional coactivator Sp110(gene name synonym)|uniprotkb:Speckled 110 kDa(gene name synonym)|uniprotkb:Interferon-induced protein 41/75(gene name synonym)|uniprotkb:SP110(gene name)|psi-mi:SP110(display_short) psi-mi:ube2o_human(display_long)|uniprotkb:UBE2O(gene name)|psi-mi:UBE2O(display_short)|uniprotkb:KIAA1734(gene name synonym)|uniprotkb:Ubiquitin-protein ligase O(gene name synonym)|uniprotkb:Ubiquitin carrier protein O(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 of 230 kDa(gene name synonym)|uniprotkb:Ubiquitin-conjugating enzyme E2 O(gene name synonym)|uniprotkb:E2/E3 hybrid ubiquitin-protein ligase UBE2O(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485359|imex:IM-26985-287 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171944.1|refseq:NP_004500.3|refseq:NP_536349.2|interpro:IPR004865(Sp100)|interpro:IPR010919(SAND-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR043563|mint:Q9HB58|ensembl:ENSG00000135899(gene)|ensembl:ENST00000358662(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000770(SAND)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type) refseq:NP_071349.3|ensembl:ENSG00000175931(gene)|ensembl:ENST00000319380(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0016604"(nuclear body)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0061631"(ubiquitin conjugating enzyme activity)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q9C0C9|reactome:R-HSA-983168 - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:foLtJoiwqgk1Urc34PzLK6PsUO09606 rogid:FftBetvip/qFQAsQxmxRnGy8ctA9606 rigid:o2S/yo9kJTwoADpkH8RetFZXfwk false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HB58 uniprotkb:P42898 intact:EBI-721477|uniprotkb:Q53TG2|uniprotkb:Q14976|uniprotkb:Q14977|uniprotkb:Q8WUZ6|uniprotkb:Q9HCT8|ensembl:ENSP00000351488|uniprotkb:B4DVI4|uniprotkb:F5H1M1 intact:EBI-372435|uniprotkb:Q7Z6M6|uniprotkb:Q9UQR2|uniprotkb:B2R7A6|uniprotkb:Q5SNW9|ensembl:ENSP00000365775|ensembl:ENSP00000365777|uniprotkb:Q5SNW6|uniprotkb:Q8IU73 psi-mi:sp110_human(display_long)|uniprotkb:Transcriptional coactivator Sp110(gene name synonym)|uniprotkb:Speckled 110 kDa(gene name synonym)|uniprotkb:Interferon-induced protein 41/75(gene name synonym)|uniprotkb:SP110(gene name)|psi-mi:SP110(display_short) psi-mi:mthr_human(display_long)|uniprotkb:MTHFR(gene name)|psi-mi:MTHFR(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485359|imex:IM-26985-287 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171944.1|refseq:NP_004500.3|refseq:NP_536349.2|interpro:IPR004865(Sp100)|interpro:IPR010919(SAND-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR043563|mint:Q9HB58|ensembl:ENSG00000135899(gene)|ensembl:ENST00000358662(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000770(SAND)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type) refseq:NP_005948.3|ensembl:ENSG00000177000(gene)|ensembl:ENST00000376590(transcript)|ensembl:ENST00000376592(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001843"(neural tube closure)|go:"GO:0004489"("methylenetetrahydrofolate reductase (NAD(P)H) activity")|go:"GO:0005829"(cytosol)|go:"GO:0006555"(methionine metabolic process)|go:"GO:0009086"(methionine biosynthetic process)|go:"GO:0031060"(regulation of histone methylation)|go:"GO:0033274"(response to vitamin B2)|go:"GO:0035999"(tetrahydrofolate interconversion)|go:"GO:0042493"|go:"GO:0043200"(response to amino acid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045202"(synapse)|go:"GO:0046500"(S-adenosylmethionine metabolic process)|go:"GO:0050660"(flavin adenine dinucleotide binding)|go:"GO:0050661"(NADP binding)|go:"GO:0050667"(homocysteine metabolic process)|go:"GO:0051593"(response to folic acid)|go:"GO:0070829"(obsolete heterochromatin maintenance)|go:"GO:0071949"(FAD binding)|go:"GO:0072341"(modified amino acid binding)|go:"GO:0106312"(methylenetetrahydrofolate reductase NADH activity)|go:"GO:0106313"(methylenetetrahydrofolate reductase NADPH activity)|interpro:IPR003171(Methylenetetrahydrofolate reductase)|interpro:IPR004621(Eukaryotic-type methylenetetrahydrofolate reductase)|interpro:IPR029041|mint:P42898|rcsb pdb:6FCX|reactome:R-HSA-196757|go:"GO:0070555"(response to interleukin-1)|refseq:XP_005263517.1|refseq:XP_005263519.1|refseq:NP_001317287.1 - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:foLtJoiwqgk1Urc34PzLK6PsUO09606 rogid:65rlcfW45WkqK2Ie1bOcnvHVzRw9606 rigid:o2S/yo9kJTwoADpkH8RetFZXfwk false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HB58 uniprotkb:O60684 intact:EBI-721477|uniprotkb:Q53TG2|uniprotkb:Q14976|uniprotkb:Q14977|uniprotkb:Q8WUZ6|uniprotkb:Q9HCT8|ensembl:ENSP00000351488|uniprotkb:B4DVI4|uniprotkb:F5H1M1 intact:EBI-359923|uniprotkb:Q5VVU3|uniprotkb:B2RDC7|ensembl:ENSP00000362728|uniprotkb:D3DPP5 psi-mi:sp110_human(display_long)|uniprotkb:Transcriptional coactivator Sp110(gene name synonym)|uniprotkb:Speckled 110 kDa(gene name synonym)|uniprotkb:Interferon-induced protein 41/75(gene name synonym)|uniprotkb:SP110(gene name)|psi-mi:SP110(display_short) psi-mi:ima7_human(display_long)|uniprotkb:KPNA6(gene name)|psi-mi:KPNA6(display_short)|uniprotkb:IPOA7(gene name synonym)|uniprotkb:Karyopherin subunit alpha-6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485359|imex:IM-26985-287 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171944.1|refseq:NP_004500.3|refseq:NP_536349.2|interpro:IPR004865(Sp100)|interpro:IPR010919(SAND-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR043563|mint:Q9HB58|ensembl:ENSG00000135899(gene)|ensembl:ENST00000358662(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000770(SAND)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type) refseq:NP_036448.1|ensembl:ENSG00000025800(gene)|ensembl:ENST00000373625(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0019079"(viral genome replication)|go:"GO:0030682"(mitigation of host defenses by symbiont)|go:"GO:0043657"(host cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0075506"(entry of viral genome into host nucleus through nuclear pore complex via importin)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1903902"(positive regulation of viral life cycle)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:O60684|rcsb pdb:4UAD|dip:DIP-27609N - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:foLtJoiwqgk1Urc34PzLK6PsUO09606 rogid:3NsSIcE6BHIqYlvfGRolUKD/5uc9606 rigid:o2S/yo9kJTwoADpkH8RetFZXfwk false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9HB58 uniprotkb:Q96B23 intact:EBI-721477|uniprotkb:Q53TG2|uniprotkb:Q14976|uniprotkb:Q14977|uniprotkb:Q8WUZ6|uniprotkb:Q9HCT8|ensembl:ENSP00000351488|uniprotkb:B4DVI4|uniprotkb:F5H1M1 intact:EBI-742108|uniprotkb:Q5XG78|uniprotkb:Q6N058|uniprotkb:Q86TB5|uniprotkb:Q8TCQ5|uniprotkb:A8K123|uniprotkb:A8KAB6|intact:EBI-10243491|uniprotkb:Q5BIX2|intact:EBI-28970197|ensembl:ENSP00000481626 psi-mi:sp110_human(display_long)|uniprotkb:Transcriptional coactivator Sp110(gene name synonym)|uniprotkb:Speckled 110 kDa(gene name synonym)|uniprotkb:Interferon-induced protein 41/75(gene name synonym)|uniprotkb:SP110(gene name)|psi-mi:SP110(display_short) psi-mi:cr025_human(display_long)|uniprotkb:C18orf25(gene name)|psi-mi:C18orf25(display_short)|uniprotkb:ARKL1(gene name synonym)|uniprotkb:ARKadia-like protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485359|imex:IM-26985-287 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001171944.1|refseq:NP_004500.3|refseq:NP_536349.2|interpro:IPR004865(Sp100)|interpro:IPR010919(SAND-like)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR043563|mint:Q9HB58|ensembl:ENSG00000135899(gene)|ensembl:ENST00000358662(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000770(SAND)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type) refseq:NP_001008240.1|refseq:NP_659492.1|ensembl:ENSP00000481626|ensembl:ENST00000619301|ensembl:ENSP00000480074|refseq:XP_011524124.1|refseq:XP_016881044.1|ensembl:ENSG00000152242(gene)|ensembl:ENST00000615052(transcript)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR029306|mint:Q96B23 - - comment:"author score: 42" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:foLtJoiwqgk1Urc34PzLK6PsUO09606 rogid:dTYuWYuPi2p41DGKE5p4cEwL9o49606 rigid:o2S/yo9kJTwoADpkH8RetFZXfwk false tandem tag:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:Q8WXF1 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-1392258|uniprotkb:Q5JTQ3|uniprotkb:Q8NCZ9|uniprotkb:Q8WXE8|uniprotkb:Q9NV36|ensembl:ENSP00000343966|ensembl:ENSP00000481916 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:pspc1_human(display_long)|uniprotkb:PSPC1(gene name)|psi-mi:PSPC1(display_short)|uniprotkb:PSP1(gene name synonym)|uniprotkb:Paraspeckle protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE refseq:XP_006719907.1|refseq:NP_001035879.1|dip:DIP-39028N|refseq:XP_016876139.1|ensembl:ENSG00000121390(gene)|ensembl:ENST00000338910(transcript)|ensembl:ENST00000619300(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034522|interpro:IPR034523|interpro:IPR035979|mint:Q8WXF1|rcsb pdb:3SDE|rcsb pdb:5IFN|rcsb pdb:5WPA - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:voQ5zJMl7FYato9iDkUYfzZ3q/k9606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:Q9Y5Q3 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-3649340|uniprotkb:B3KNE1|uniprotkb:Q9H1F1|ensembl:ENSP00000362410 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:mafb_human(display_long)|uniprotkb:MAFB(gene name)|psi-mi:MAFB(display_short)|uniprotkb:KRML(gene name synonym)|uniprotkb:V-maf musculoaponeurotic fibrosarcoma oncogene homolog B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE refseq:NP_005452.2|ensembl:ENSP00000362410|ensembl:ENSG00000204103(gene)|ensembl:ENST00000373313(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0045444"(fat cell differentiation)|go:"GO:0045637"(regulation of myeloid cell differentiation)|go:"GO:0045647"(negative regulation of erythrocyte differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048538"(thymus development)|interpro:IPR004826(Maf transcription factor)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR013592(Maf transcription factor, N-terminal)|interpro:IPR024874|interpro:IPR028571|mint:Q9Y5Q3|reactome:R-HSA-5617472|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007379"(segment specification)|go:"GO:0007423"(sensory organ development)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0008134"(transcription factor binding)|go:"GO:0021571"(rhombomere 5 development)|go:"GO:0021572"(rhombomere 6 development)|go:"GO:0021599"(abducens nerve formation)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0035284"(brain segmentation)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0005634"(nucleus) - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:0TC5DeljJqY/ClydzzdvMScyhzI9606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:P26196 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:Q13523 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-395940|uniprotkb:Q8TDP2|uniprotkb:Q96QT7|uniprotkb:Q9UEE6|uniprotkb:Q5TAY8|uniprotkb:A8K5C9|uniprotkb:Q5D0F6|uniprotkb:Q8IVC3|intact:EBI-1058380|ensembl:ENSP00000337194|ensembl:ENSP00000433547 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:prp4b_human(display_long)|uniprotkb:PRPF4B(gene name)|psi-mi:PRPF4B(display_short)|uniprotkb:KIAA0536(gene name synonym)|uniprotkb:PRP4(gene name synonym)|uniprotkb:PRP4H(gene name synonym)|uniprotkb:PRP4K(gene name synonym)|uniprotkb:PRP4 pre-mRNA-processing factor 4 homolog(gene name synonym)|uniprotkb:PRP4 kinase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE refseq:NP_003904.3|ensembl:ENSG00000112739(gene)|ensembl:ENST00000337659(transcript)|ensembl:ENST00000480058(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR044092|mint:Q13523|rcsb pdb:4IAN|rcsb pdb:4IFC|rcsb pdb:4IIR|rcsb pdb:4IJP|rcsb pdb:6CNH|rcsb pdb:6PJJ|rcsb pdb:6PK6|rcsb pdb:6QX9|refseq:XP_016866899.1|refseq:XP_016866900.1|refseq:XP_016866901.1|refseq:XP_016866902.1|refseq:XP_016866903.1|refseq:XP_016866904.1|refseq:XP_016866905.1|refseq:XP_016866906.1|refseq:XP_016866907.1|refseq:XP_016866908.1|refseq:XP_016866909.1|refseq:XP_016866910.1|refseq:XP_016866911.1|refseq:XP_016866912.1|refseq:XP_016866913.1|refseq:XP_016866914.1|refseq:XP_016866915.1|refseq:XP_016866916.1|refseq:XP_016866917.1|refseq:XP_016866918.1|refseq:XP_016866919.1|refseq:XP_016866920.1 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:ZklPbRvRbbVRJYqV3JkS2jG3EIc9606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:Q9NXE8 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-746052|uniprotkb:A0JLM3|uniprotkb:Q68DK5|ensembl:ENSP00000477799|ensembl:ENSP00000478070 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:cwc25_human(display_long)|uniprotkb:CWC25(gene name)|psi-mi:CWC25(display_short)|uniprotkb:CCDC49(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 49(gene name synonym)|uniprotkb:Spliceosome-associated protein homolog CWC25(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE refseq:NP_060218.1|ensembl:ENSG00000273559(gene)|ensembl:ENSG00000276761(gene)|ensembl:ENST00000614790(transcript)|ensembl:ENST00000614868(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0016607"(nuclear speck)|go:"GO:0071006"(U2-type catalytic step 1 spliceosome)|interpro:IPR019339|interpro:IPR022209|mint:Q9NXE8|rcsb pdb:5YZG|rcsb pdb:6ZYM|reactome:R-HSA-72163 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:tHUYBNAjYV/4gMcTCaos3Yo+DwY9606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:P62917 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-438527|ensembl:ENSP00000262584|ensembl:ENSP00000378378|ensembl:ENSP00000433464|uniprotkb:P25120|uniprotkb:Q567Q7|uniprotkb:Q969V7|uniprotkb:Q9BWQ9|uniprotkb:A8K094|uniprotkb:D3DWN2 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:rl8_human(display_long)|uniprotkb:RPL8(gene name)|psi-mi:RPL8(display_short)|uniprotkb:Large ribosomal subunit protein uL2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE rcsb pdb:4CCN|rcsb pdb:4CCO|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:4Y3O|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000161016(gene)|ensembl:ENST00000262584(transcript)|ensembl:ENST00000394920(transcript)|ensembl:ENST00000528957(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0098794"(postsynapse)|interpro:IPR002171(Ribosomal protein L2)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR014726(Ribosomal protein L2, domain 3)|interpro:IPR022666|interpro:IPR022669|interpro:IPR022671|interpro:IPR023672|mint:P62917|rcsb pdb:4CCM|refseq:NP_000964.1|refseq:NP_150644.1|refseq:NP_001304700.1|refseq:NP_001304711.1|dip:DIP-37967N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:+b/ORzdCy/nqFLsKRV9VhIZgdjg9606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:Q8N1G2 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-2691086|uniprotkb:Q96FJ9|uniprotkb:Q14670|uniprotkb:A8K949|ensembl:ENSP00000362550 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:cmtr1_human(display_long)|uniprotkb:CMTR1(gene name)|psi-mi:CMTR1(display_short)|uniprotkb:Cap methyltransferase 1(gene name synonym)|uniprotkb:Cap1 2'O-ribose methyltransferase 1(gene name synonym)|uniprotkb:FTSJD2(gene name synonym)|uniprotkb:FtsJ methyltransferase domain-containing protein 2(gene name synonym)|uniprotkb:Interferon-stimulated gene 95 kDa protein(gene name synonym)|uniprotkb:KIAA0082(gene name synonym)|uniprotkb:MTR1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE refseq:NP_055865.1|ensembl:ENSG00000137200(gene)|ensembl:ENST00000373451(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0004483"("mRNA (nucleoside-2'-O-)-methyltransferase activity")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006370"(7-methylguanosine mRNA capping)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0080009"(mRNA methylation)|go:"GO:0097309"(cap1 mRNA methylation)|interpro:IPR000467(D111/G-patch)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR002877(Ribosomal RNA methyltransferase RrmJ/FtsJ)|interpro:IPR025816|interpro:IPR029063|interpro:IPR030376|mint:Q8N1G2|rcsb pdb:4N48|rcsb pdb:4N49|rcsb pdb:4N4A - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:mMoDk5J/tBCaxISq1Oju9BY0RVA9606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:Q96QC0 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-1210346|uniprotkb:O00405|ensembl:ENSP00000365694|ensembl:ENSP00000373080|ensembl:ENSP00000389299|ensembl:ENSP00000407181|ensembl:ENSP00000407310|ensembl:ENSP00000413554|ensembl:ENSP00000416060 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:pp1ra_human(display_long)|uniprotkb:PPP1R10(gene name)|psi-mi:PPP1R10(display_short)|uniprotkb:CAT53(gene name synonym)|uniprotkb:FB19(gene name synonym)|uniprotkb:PNUTS(gene name synonym)|uniprotkb:Phosphatase 1 nuclear targeting subunit(gene name synonym)|uniprotkb:MHC class I region proline-rich protein CAT53(gene name synonym)|uniprotkb:Protein FB19(gene name synonym)|uniprotkb:PP1-binding protein of 114 kDa(gene name synonym)|uniprotkb:p99(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE refseq:XP_011513024.1|refseq:NP_002705.2|refseq:XP_006715193.1|refseq:XP_016866484.1|dip:DIP-39343N|ensembl:ENSG00000204569(gene)|ensembl:ENSG00000206489(gene)|ensembl:ENSG00000227804(gene)|ensembl:ENSG00000230995(gene)|ensembl:ENSG00000231737(gene)|ensembl:ENSG00000235291(gene)|ensembl:ENSG00000238104(gene)|ensembl:ENST00000376511(transcript)|ensembl:ENST00000383586(transcript)|ensembl:ENST00000420949(transcript)|ensembl:ENST00000424446(transcript)|ensembl:ENST00000426299(transcript)|ensembl:ENST00000429597(transcript)|ensembl:ENST00000449113(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0016604"(nuclear body)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0046872"(metal ion binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:1904290"(negative regulation of mitotic DNA damage checkpoint)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR017923|interpro:IPR035441|interpro:IPR036855|mint:Q96QC0|go:"GO:0000785"(chromatin) - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:ZWueXxqNFYPT0WhbfYdR3d2H2G89606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:P49756 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-2211856|uniprotkb:Q9UEQ5|uniprotkb:Q9UIE9|uniprotkb:A0PJL9|uniprotkb:B2RNA8|uniprotkb:B3KT03|uniprotkb:Q2TA72|uniprotkb:Q5XJ17|uniprotkb:Q6P665|uniprotkb:Q9H6A1|intact:EBI-2839256|intact:EBI-2859423|ensembl:ENSP00000261973|ensembl:ENSP00000431150 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:rbm25_human(display_long)|uniprotkb:RBM25(gene name)|psi-mi:RBM25(display_short)|uniprotkb:RNPC7(gene name synonym)|uniprotkb:RNA-binding motif protein 25(gene name synonym)|uniprotkb:RNA-binding region-containing protein 7(gene name synonym)|uniprotkb:Protein S164(gene name synonym)|uniprotkb:Arg/Glu/Asp-rich protein of 120 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE refseq:XP_011535346.1|refseq:NP_067062.1|refseq:XP_011535347.1|ensembl:ENSG00000119707(gene)|ensembl:ENST00000261973(transcript)|ensembl:ENST00000527432(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002483(Splicing factor PWI)|interpro:IPR034268|interpro:IPR035979|interpro:IPR036483|mint:P49756|rcsb pdb:3V53|interpro:IPR012677(Nucleotide-binding, alpha-beta plait) - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:VRZ6bJro7qw+BXS0rpYZoiD8iAM9606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:Q9BZE4 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-1056249|uniprotkb:O95446|uniprotkb:Q9NVJ8|uniprotkb:B3KMC5|uniprotkb:B4DY13|uniprotkb:B7Z7A3|uniprotkb:Q5T3R8|ensembl:ENSP00000354040 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:gtpb4_human(display_long)|uniprotkb:GTPBP4(gene name)|psi-mi:GTPBP4(display_short)|uniprotkb:CRFG(gene name synonym)|uniprotkb:NOG1(gene name synonym)|uniprotkb:Chronic renal failure gene protein(gene name synonym)|uniprotkb:GTP-binding protein NGB(gene name synonym)|uniprotkb:Nucleolar GTP-binding protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE refseq:NP_036473.2|ensembl:ENSG00000107937(gene)|ensembl:ENST00000360803(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031965"(nuclear membrane)|go:"GO:0033342"(negative regulation of collagen binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR006073(GTP1/OBG)|interpro:IPR010674(Nucleolar GTP-binding 1)|interpro:IPR012973(NOG, C-terminal)|interpro:IPR024926|interpro:IPR027417|interpro:IPR031167|interpro:IPR041623|mint:Q9BZE4|rcsb pdb:6LSS|rcsb pdb:6LU8 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:wTcBrIj6c27um4RnJH81grRgutc9606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:P47914 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-714039|uniprotkb:Q6IPY3|ensembl:ENSP00000418346|ensembl:ENSP00000418868|ensembl:ENSP00000420673|ensembl:ENSP00000294189|ensembl:ENSP00000417048|ensembl:ENSP00000418153|uniprotkb:B2R4M8|uniprotkb:A8K0H3 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:rl29_human(display_long)|uniprotkb:Cell surface heparin-binding protein HIP(gene name synonym)|uniprotkb:RPL29(gene name)|psi-mi:RPL29(display_short)|uniprotkb:Large ribosomal subunit protein eL29(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE ensembl:ENST00000294189(transcript)|ensembl:ENST00000466397(transcript)|ensembl:ENST00000475248(transcript)|ensembl:ENST00000479017(transcript)|ensembl:ENST00000492277(transcript)|ensembl:ENST00000495383(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0007566"(embryo implantation)|go:"GO:0008201"(heparin binding)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR002673(Ribosomal protein L29e)|mint:P47914|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|ensembl:ENSG00000162244(gene)|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_000983.1|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:XZUSMDDzycAi6QEXYbljXaeVg0U9606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:P23246 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-355453|uniprotkb:P30808|uniprotkb:Q5SZ71|ensembl:ENSP00000349748 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:sfpq_human(display_long)|uniprotkb:SFPQ(gene name)|psi-mi:SFPQ(display_short)|uniprotkb:PSF(gene name synonym)|uniprotkb:Polypyrimidine tract-binding protein-associated-splicing factor(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 100 kDa subunit(gene name synonym)|uniprotkb:100 kDa DNA-pairing protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE refseq:NP_005057.1|ensembl:ENSG00000116560(gene)|ensembl:ENST00000357214(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0003723"(RNA binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0042382"(paraspeckles)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0005634"(nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0048511"(rhythmic process)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:1902177"(positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034525|interpro:IPR034526|interpro:IPR035979|mint:P23246|rcsb pdb:4WII|rcsb pdb:4WIJ|rcsb pdb:4WIK|rcsb pdb:5WPA|rcsb pdb:6NCQ|rcsb pdb:6OWJ|rcsb pdb:6WMZ|rcsb pdb:7LRQ|rcsb pdb:7LRU|reactome:R-HSA-8849468|reactome:R-HSA-9635465|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|refseq:XP_005271169.1|refseq:XP_005271170.1|refseq:XP_005271172.1|refseq:XP_016857542.1|refseq:XP_016857543.1|dip:DIP-31272N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:B7mSc6tthLbSHo0qz0SMZBSl3HA9606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:Q3MHD2 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-725133|uniprotkb:Q86YB1|uniprotkb:Q96NL5|ensembl:ENSP00000293406|ensembl:ENSP00000466718 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:lsm12_human(display_long)|uniprotkb:LSM12(gene name)|psi-mi:LSM12(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE refseq:NP_689557.1|ensembl:ENSG00000161654(gene)|ensembl:ENST00000293406(transcript)|ensembl:ENST00000591247(transcript)|interpro:IPR019181|interpro:IPR039683|mint:Q3MHD2 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:SY9HUXXLZyXhttFb+AXkMh0QOek9606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:P62136 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-357253|uniprotkb:P08129|uniprotkb:P20653|uniprotkb:P22802|uniprotkb:B2R908|intact:EBI-2623163|uniprotkb:Q07161|intact:EBI-2556927|uniprotkb:A6NNR3|ensembl:ENSP00000365936 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:pp1a_human(display_long)|uniprotkb:PPP1CA(gene name)|psi-mi:PPP1CA(display_short)|uniprotkb:PPP1A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE refseq:NP_001008709.1|refseq:NP_002699.1|refseq:NP_996756.1|dip:DIP-221N|dip:DIP-38195N|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0036496"(regulation of translational initiation by eIF2 alpha dephosphorylation)|go:"GO:0042587"(glycogen granule)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0051301"(cell division)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904886"(beta-catenin destruction complex disassembly)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|interpro:IPR037979|mint:P62136|rcsb pdb:3E7A|rcsb pdb:3E7B|rcsb pdb:3EGG|rcsb pdb:3EGH|rcsb pdb:3HVQ|rcsb pdb:3N5U|rcsb pdb:3V4Y|rcsb pdb:4G9J|rcsb pdb:4MOV|rcsb pdb:4MOY|rcsb pdb:4MP0|rcsb pdb:4XPN|rcsb pdb:5IOH|rcsb pdb:6ALZ|rcsb pdb:6CZO|rcsb pdb:6DCX|rcsb pdb:6DNO|rcsb pdb:6G0I|rcsb pdb:6G0J|rcsb pdb:6GHM|rcsb pdb:6OBN|rcsb pdb:6OBP|rcsb pdb:6OBQ|rcsb pdb:6OBR|rcsb pdb:6OBS|rcsb pdb:6OBU|rcsb pdb:6ZEE|rcsb pdb:6ZEF|rcsb pdb:6ZEG|rcsb pdb:6ZEH|rcsb pdb:6ZEI|rcsb pdb:6ZEJ|rcsb pdb:6ZK6|reactome:R-HSA-163560|reactome:R-HSA-180024|reactome:R-HSA-2173788|reactome:R-HSA-400253|go:"GO:0098793"(presynapse)|ensembl:ENSG00000172531(gene)|ensembl:ENST00000376745(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0030324"(lung development) - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:IMypaKng+5AECbCd3N72pgzUlxQ9606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:P46109 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-910|uniprotkb:A8KA44|intact:EBI-3451075|uniprotkb:D3DX35|ensembl:ENSP00000346300|ensembl:ENSP00000396646 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:crkl_human(display_long)|uniprotkb:CRKL(gene name)|psi-mi:CRKL(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE refseq:NP_005198.1|dip:DIP-29165N|ensembl:ENSG00000099942(gene)|ensembl:ENST00000354336(transcript)|ensembl:ENST00000411769(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001568"(blood vessel development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001764"(neuron migration)|go:"GO:0001783"(B cell apoptotic process)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007254"(JNK cascade)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007416"(synapse assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0008584"(male gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016358"(dendrite development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035685"(helper T cell diapedesis)|go:"GO:0035690"|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048538"(thymus development)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0060017"(parathyroid gland development)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060465"(pharynx development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0098749"(cerebellar neuron development)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903977"(positive regulation of glial cell migration)|go:"GO:1904393"(regulation of skeletal muscle acetylcholine-gated channel clustering)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:2000404"(regulation of T cell migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035457|interpro:IPR035458|interpro:IPR036028|interpro:IPR036860|mint:P46109|rcsb pdb:2BZX|rcsb pdb:2BZY|rcsb pdb:2DBK|rcsb pdb:2EO3|rcsb pdb:2LQN|rcsb pdb:2LQW|reactome:R-HSA-170968|reactome:R-HSA-186763|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-9027284|reactome:R-HSA-912631 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:1YwlbUPPuijisz7AJM4Qkp7yJBI9606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:P39019 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-354451|ensembl:ENSP00000469228|ensembl:ENSP00000470004|ensembl:ENSP00000470972 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:rs19_human(display_long)|uniprotkb:RPS19(gene name)|psi-mi:RPS19(display_short)|uniprotkb:Small ribosomal subunit protein eS19(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE refseq:NP_001013.1|ensembl:ENSG00000105372(gene)|ensembl:ENST00000593863(transcript)|ensembl:ENST00000598742(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003723"(RNA binding)|ensembl:ENST00000600467(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0007000"(nucleolus organization)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0060265"(positive regulation of respiratory burst involved in inflammatory response)|go:"GO:0060266"(negative regulation of respiratory burst involved in inflammatory response)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001266(Ribosomal protein S19e)|interpro:IPR018277|interpro:IPR036388|interpro:IPR036390|mint:P39019|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001308412.1|refseq:NP_001308413.1 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:3YqdJJJG+2nqoBf3PLu1fs7pVkY9606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:Q9Y3C1 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-5453434|uniprotkb:Q6IAI6|uniprotkb:Q8IXL5|uniprotkb:Q6PIM0|uniprotkb:B4DV13|uniprotkb:D6RGD3|uniprotkb:Q05D05|ensembl:ENSP00000480832 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:nop16_human(display_long)|uniprotkb:NOP16(gene name)|psi-mi:NOP16(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 3(gene name synonym)|uniprotkb:CGI-117(orf name)|uniprotkb:HSPC111(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE refseq:NP_057475.2|refseq:NP_001304904.1|refseq:NP_001243468.2|refseq:NP_001278234.1|refseq:NP_001278236.1|refseq:NP_001278237.1|refseq:NP_001243469.2|ensembl:ENSG00000048162(gene)|ensembl:ENST00000614830(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019002|mint:Q9Y3C1 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:HdIqgMgye+B+sa3XiPdqvLXbcR89606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:Q8N684 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-746909|uniprotkb:C9K0Q4|uniprotkb:Q7Z3H9|uniprotkb:Q9H025|uniprotkb:Q9H9V1|uniprotkb:B3KU04|ensembl:ENSP00000378352 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:cpsf7_human(display_long)|uniprotkb:Cleavage and polyadenylation specificity factor 59 kDa subunit(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 59 kDa subunit(gene name synonym)|uniprotkb:CPSF7(gene name)|psi-mi:CPSF7(display_short)|uniprotkb:Cleavage factor Im complex 59 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE refseq:NP_001129512.1|refseq:NP_001136037.1|refseq:NP_079087.3|refseq:XP_011543560.1|refseq:XP_011543561.1|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0016020"(membrane)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034770|interpro:IPR034772|interpro:IPR034773|interpro:IPR035979|mint:Q8N684|rcsb pdb:3N9U|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|ensembl:ENSG00000149532(gene)|ensembl:ENST00000394888(transcript)|refseq:XP_005274356.1|reactome:R-HSA-9013422 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:bfliZhw27GRZMSQpYRZ/x/tWGh49606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:P48426 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-3924422|uniprotkb:Q5VUX3|uniprotkb:D3DRV1|uniprotkb:B0YJ66|uniprotkb:P53807|ensembl:ENSP00000365757|uniprotkb:B4DGX2 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:pi42a_human(display_long)|uniprotkb:PIP4K2A(gene name)|psi-mi:PIP4K2A(display_short)|uniprotkb:PIP5K2(gene name synonym)|uniprotkb:PIP5K2A(gene name synonym)|uniprotkb:Diphosphoinositide kinase 2-alpha(gene name synonym)|uniprotkb:PIP5KIII(gene name synonym)|uniprotkb:"PtdIns(4)P-5-kinase B isoform"(gene name synonym)|uniprotkb:"PtdIns(4)P-5-kinase C isoform"(gene name synonym)|uniprotkb:"PtdIns(5)P-4-kinase isoform 2-alpha"(gene name synonym)|uniprotkb:1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha(gene name synonym)|uniprotkb:Phosphatidylinositol 5-phosphate 4-kinase type II alpha(gene name synonym)|uniprotkb:PI5P4KA(gene name synonym)|uniprotkb:Phosphatidylinositol 5-Phosphate 4-Kinase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE refseq:NP_005019.2|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016308"(1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:0016309"(1-phosphatidylinositol-5-phosphate 4-kinase activity)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0061909"(autophagosome-lysosome fusion)|go:"GO:0090119"(vesicle-mediated cholesterol transport)|go:"GO:0090217"(negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity)|ensembl:ENST00000376573(transcript)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR002498(Phosphatidylinositol-4-phosphate 5-kinase, core)|interpro:IPR023610|interpro:IPR027484|mint:P48426|rcsb pdb:2YBX|rcsb pdb:6OSP|rcsb pdb:6UX9|rcsb pdb:6YM3|rcsb pdb:6YM4|rcsb pdb:6YM5|rcsb pdb:7N6Z|rcsb pdb:7N7J|rcsb pdb:7N7K|rcsb pdb:7N7L|rcsb pdb:7N7M|rcsb pdb:7N7N|rcsb pdb:7N7O|reactome:R-HSA-1660499|reactome:R-HSA-6811555|reactome:R-HSA-6811558|reactome:R-HSA-8847453|go:"GO:1902635"(1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process)|ensembl:ENSG00000150867(gene)|refseq:NP_001316991.1|refseq:XP_016871819.1|refseq:XP_016871820.1 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:Fmsp/H2ucCjs7wyiCgEqe9Y5UT49606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:Q15233 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-350527|ensembl:ENSP00000503233|uniprotkb:O00201|uniprotkb:P30807|uniprotkb:Q12786|uniprotkb:Q9BQC5|ensembl:ENSP00000276079|ensembl:ENSP00000362947|ensembl:ENSP00000406673|ensembl:ENSP00000410299|ensembl:ENSP00000415777|ensembl:ENSP00000503031|ensembl:ENSP00000504314|ensembl:ENSP00000504351|uniprotkb:D3DVV4|uniprotkb:B7Z4C2|uniprotkb:F5GYZ3 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:nono_human(display_long)|uniprotkb:NONO(gene name)|psi-mi:NONO(display_short)|uniprotkb:NRB54(gene name synonym)|uniprotkb:54 kDa nuclear RNA- and DNA-binding protein(gene name synonym)|uniprotkb:"p54(nrb)"(gene name synonym)|uniprotkb:55 kDa nuclear protein(gene name synonym)|uniprotkb:NMT55(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 52 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE refseq:NP_001138880.1|refseq:NP_001138881.1|refseq:NP_001138882.1|refseq:NP_031389.3|ensembl:ENSG00000147140(gene)|ensembl:ENST00000276079(transcript)|ensembl:ENST00000373841(transcript)|ensembl:ENST00000420903(transcript)|ensembl:ENST00000450092(transcript)|ensembl:ENST00000454976(transcript)|ensembl:ENST00000677274(transcript)|ensembl:ENST00000677446(transcript)|ensembl:ENST00000677612(transcript)|ensembl:ENST00000678231(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0042382"(paraspeckles)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034552|interpro:IPR035979|mint:Q15233|rcsb pdb:3SDE|rcsb pdb:5IFM|rcsb pdb:6WMZ|rcsb pdb:7LRQ|dip:DIP-29951N - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:5W3ooO4h0qh3GKO+WjDrLBhihHA9606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:Q96SL8 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-2869737|uniprotkb:Q6ZMJ7|uniprotkb:A2RU72|ensembl:ENSP00000221665 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:fiz1_human(display_long)|uniprotkb:FIZ1(gene name)|psi-mi:FIZ1(display_short)|uniprotkb:ZNF798(gene name synonym)|uniprotkb:Zinc finger protein 798(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE refseq:NP_116225.2|refseq:XP_005259409.1|ensembl:ENSG00000179943(gene)|ensembl:ENST00000221665(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005634"(nucleus)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q96SL8 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:t8VQRjTuC7hYthJIEkWwUpf0U9M9606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:O43290 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-607761|ensembl:ENSP00000310448|uniprotkb:A6NDN1|uniprotkb:Q53GB5 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:snut1_human(display_long)|uniprotkb:U4/U6.U5 tri-snRNP-associated 110 kDa protein(gene name synonym)|uniprotkb:SART1(gene name)|psi-mi:SART1(display_short)|uniprotkb:SNU66 homolog(gene name synonym)|uniprotkb:Squamous cell carcinoma antigen recognized by T-cells 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE ensembl:ENSG00000175467(gene)|ensembl:ENST00000312397(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000481"(maturation of 5S rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0045585"(positive regulation of cytotoxic T cell differentiation)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR005011(SART-1 protein)|mint:O43290|rcsb pdb:4PYU|rcsb pdb:5O9Z|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|reactome:R-HSA-72163|refseq:NP_005137.1|dip:DIP-33360N - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:egvWHy7UXW+MkGtGEW984yvRU9k9606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:P55081 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-1048159|uniprotkb:Q86TG6|ensembl:ENSP00000267812 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:mfap1_human(display_long)|uniprotkb:Spliceosome B complex protein MFAP1(gene name synonym)|uniprotkb:MFAP1(gene name)|psi-mi:MFAP1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE refseq:NP_005917.2|ensembl:ENSG00000140259(gene)|ensembl:ENST00000267812(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0001527"(microfibril)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005684"(U2-type spliceosomal complex)|go:"GO:0005813"(centrosome)|go:"GO:0071005"(U2-type precatalytic spliceosome)|interpro:IPR009730(Micro-fibrillar-associated 1, C-terminal)|interpro:IPR033194|mint:P55081|rcsb pdb:5F5S|rcsb pdb:5O9Z|rcsb pdb:6AHD|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|reactome:R-HSA-2129379 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:38SGUW2hc2ZwbmyTO52uGQRw79U9606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:Q99575 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-366741|uniprotkb:Q15037|uniprotkb:A8K5W9|intact:EBI-2560204|ensembl:ENSP00000339529|ensembl:ENSP00000385787 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:pop1_human(display_long)|uniprotkb:POP1(gene name)|psi-mi:POP1(display_short)|uniprotkb:KIAA0061(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE refseq:NP_001139332.1|refseq:NP_001139333.1|refseq:NP_055844.2|ensembl:ENSG00000104356(gene)|ensembl:ENST00000349693(transcript)|ensembl:ENST00000401707(transcript)|go:"GO:0000172"(ribonuclease MRP complex)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0004526"(ribonuclease P activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005655"(nucleolar ribonuclease P complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008033"(tRNA processing)|go:"GO:0016078"(tRNA catabolic process)|go:"GO:0030681"(multimeric ribonuclease P complex)|go:"GO:0033204"(ribonuclease P RNA binding)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR009723(Ribonuclease P/MRP, POP1)|interpro:IPR012590(POPLD)|interpro:IPR039182|mint:Q99575|rcsb pdb:6AHR|rcsb pdb:6AHU|reactome:R-HSA-6784531 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:XJxSr17TfVuetXKgpQPjs2QKMV49606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:Q96EY4 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-1045338|uniprotkb:Q0P6E4|uniprotkb:Q0P6J1|uniprotkb:Q9NUR7|ensembl:ENSP00000351380 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:tma16_human(display_long)|uniprotkb:TMA16(gene name)|psi-mi:TMA16(display_short)|uniprotkb:C4orf43(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE refseq:NP_060822.2|ensembl:ENSG00000198498(gene)|ensembl:ENST00000358572(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|interpro:IPR021346|interpro:IPR038356|mint:Q96EY4|rcsb pdb:6LSS|rcsb pdb:6LU8 - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:SpEUtN6fodLyKZOgY6Y7AXfVBRY9606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:Q9BU76 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-742459|uniprotkb:Q6P5Y0|uniprotkb:Q6ZTZ6|uniprotkb:Q6ZWA6|uniprotkb:Q8IZH3|ensembl:ENSP00000272139 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:mmta2_human(display_long)|uniprotkb:MMTAG2(gene name)|psi-mi:MMTAG2(display_short)|uniprotkb:C1orf35(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE refseq:NP_077295.1|mint:Q9BU76|reactome:R-HSA-6798695|ensembl:ENSG00000143793(gene)|ensembl:ENST00000272139(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0034774"(secretory granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR019315|interpro:IPR039207 - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:TwnLhBYwwR6yPCw3sd7g/sPHJd09606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:Q8WWM7 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-948363|ensembl:ENSP00000338718|uniprotkb:O95135|uniprotkb:Q6NVJ8|uniprotkb:Q6PJW6|uniprotkb:Q8IU61|uniprotkb:Q8IU95|uniprotkb:Q8WWM3|uniprotkb:Q8WWM4|uniprotkb:Q8WWM5|uniprotkb:Q8WWM6|uniprotkb:Q99703|uniprotkb:B9EGM2|uniprotkb:E9PAR9|uniprotkb:A8K1R6|uniprotkb:Q63ZY4 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:atx2l_human(display_long)|uniprotkb:Ataxin-2 domain protein(gene name synonym)|uniprotkb:Ataxin-2-related protein(gene name synonym)|uniprotkb:ATXN2L(gene name)|psi-mi:ATXN2L(display_short)|uniprotkb:A2D(gene name synonym)|uniprotkb:A2LG(gene name synonym)|uniprotkb:A2LP(gene name synonym)|uniprotkb:A2RP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE ensembl:ENSG00000168488(gene)|ensembl:ENST00000336783(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045296"(cadherin binding)|interpro:IPR009604(Ataxin-2, N-terminal)|interpro:IPR009818(Ataxin-2, C-terminal)|interpro:IPR025852|mint:Q8WWM7|refseq:NP_009176.2|refseq:NP_663760.1|refseq:NP_680780.1|refseq:NP_680781.1|refseq:XP_005255123.1|refseq:NP_059867.3|refseq:NP_680782.1 - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:t7lrS10IM/5pt+rrbqBRowZ6b+09606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:P62750 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-353254|uniprotkb:P29316|uniprotkb:Q92774|uniprotkb:P39024|uniprotkb:B2R5B2|ensembl:ENSP00000389103 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:rl23a_human(display_long)|uniprotkb:RPL23A(gene name)|psi-mi:RPL23A(display_short)|uniprotkb:Large ribosomal subunit protein uL23(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|refseq:NP_000975.2|ensembl:ENSG00000198242(gene)|ensembl:ENST00000422514(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904841"(TORC2 complex binding)|interpro:IPR001014(Ribosomal protein L23, conserved site)|interpro:IPR005633(Ribosomal protein L23/L25, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR013025(Ribosomal protein L25/L23)|interpro:IPR019985|mint:P62750|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:lA1ubRFO9/Tl54Z1dKUzoCKvpAo9606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:Q5T3I0 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-2372076|uniprotkb:Q5T3I1|uniprotkb:Q6ZUE7|uniprotkb:Q8IWG8|uniprotkb:Q9NXH4 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:gptc4_human(display_long)|uniprotkb:GPATCH4(gene name)|psi-mi:GPATCH4(display_short)|uniprotkb:GPATC4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE interpro:IPR000467(D111/G-patch)|mint:Q5T3I0|go:"GO:0003723"(RNA binding) - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:R2hFHYGQh2jmLbLg+BNATVimtNA9606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:Q9BRJ6 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-751612|ensembl:ENSP00000350011|ensembl:ENSP00000380286|ensembl:ENSP00000380288 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:cg050_human(display_long)|uniprotkb:FP15621(orf name)|uniprotkb:C7orf50(gene name)|psi-mi:C7orf50(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE refseq:NP_001127867.1|refseq:NP_001127868.1|refseq:NP_115726.1|refseq:NP_001305181.1|ensembl:ENSG00000146540(gene)|ensembl:ENST00000357429(transcript)|ensembl:ENST00000397098(transcript)|ensembl:ENST00000397100(transcript)|interpro:IPR019327|mint:Q9BRJ6|go:"GO:0003723"(RNA binding) - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:POftCOri0Nj8YUd5Kc3nNMDb41A9606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:Q5HYJ3 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-751192|uniprotkb:Q6PIU3|uniprotkb:Q8TC53|uniprotkb:B2R9C2|ensembl:ENSP00000351631 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:fa76b_human(display_long)|uniprotkb:FAM76B(gene name)|psi-mi:FAM76B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE refseq:NP_653265.3|ensembl:ENSG00000077458(gene)|ensembl:ENST00000358780(transcript)|go:"GO:0016607"(nuclear speck)|interpro:IPR029661|interpro:IPR032017|mint:Q5HYJ3 - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:FWmHMXjKuPdNvpa793hQ1F+Tb909606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:Q8TAD8 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-749336|uniprotkb:Q96SP9|uniprotkb:Q9H9T7|intact:EBI-1046254|ensembl:ENSP00000296215 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:snip1_human(display_long)|uniprotkb:SNIP1(gene name)|psi-mi:SNIP1(display_short)|uniprotkb:FHA domain-containing protein SNIP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE refseq:NP_078976.2|ensembl:ENSG00000163877(gene)|ensembl:ENST00000296215(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-38956N|mint:Q8TAD8|rcsb pdb:5Z56|rcsb pdb:5Z57|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|rcsb pdb:5Z58|rcsb pdb:6FF7|rcsb pdb:7ABG|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0035196"(production of miRNAs involved in gene silencing by miRNA)|go:"GO:0071005"(U2-type precatalytic spliceosome)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain) - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:2UWnTY01RhPuUx3PepGug23l11U9606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:P51608 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-1189067|uniprotkb:O15233|uniprotkb:Q6QHH9|uniprotkb:Q7Z384|ensembl:ENSP00000301948 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:mecp2_human(display_long)|uniprotkb:MECP2(gene name)|psi-mi:MECP2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE refseq:NP_001104262.1|refseq:NP_004983.1|refseq:NP_001303266.1|ensembl:ENSG00000169057(gene)|ensembl:ENST00000303391(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000792"(heterochromatin)|go:"GO:0001662"(behavioral fear response)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001964"(startle response)|go:"GO:0001976"(nervous system process involved in regulation of systemic arterial blood pressure)|go:"GO:0002087"(regulation of respiratory gaseous exchange by nervous system process)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006020"(inositol metabolic process)|go:"GO:0006342"|go:"GO:0006349"(regulation of gene expression by genomic imprinting)|go:"GO:0006541"(glutamine metabolic process)|go:"GO:0006576"(cellular biogenic amine metabolic process)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007416"(synapse assembly)|go:"GO:0007585"(respiratory gaseous exchange by respiratory system)|go:"GO:0007616"(long-term memory)|go:"GO:0008104"(protein localization)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0008542"(visual learning)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010971"(positive regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016358"(dendrite development)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016571"(histone methylation)|go:"GO:0016573"(histone acetylation)|go:"GO:0019230"(proprioception)|go:"GO:0019233"(sensory perception of pain)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0021591"(ventricular system development)|go:"GO:0032048"(cardiolipin metabolic process)|go:"GO:0035176"(social behavior)|go:"GO:0035197"(siRNA binding)|go:"GO:0042551"(neuron maturation)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051151"(negative regulation of smooth muscle cell differentiation)|go:"GO:0051707"(response to other organism)|go:"GO:0060079"(excitatory postsynaptic potential)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0098794"(postsynapse)|go:"GO:1900114"(positive regulation of histone H3-K9 trimethylation)|go:"GO:1905643"(positive regulation of DNA methylation)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000820"(negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation)|interpro:IPR001739(Methyl-CpG DNA binding)|interpro:IPR016177(DNA-binding, integrase-type)|interpro:IPR017353(Methyl-CpG binding protein MeCP2)|mint:P51608|rcsb pdb:1QK9|rcsb pdb:3C2I|rcsb pdb:5BT2|rcsb pdb:6C1Y|rcsb pdb:6OGJ|rcsb pdb:6OGK|reactome:R-HSA-8986944|reactome:R-HSA-9022534|reactome:R-HSA-9022535|reactome:R-HSA-9022537|reactome:R-HSA-9022538|reactome:R-HSA-9022692|reactome:R-HSA-9022699|reactome:R-HSA-9022702|reactome:R-HSA-9022707|reactome:R-HSA-9022927|dip:DIP-39983N - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:7c5ZZAZsqV7AciGN4hzFNWJLeUk9606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:P63241 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-373150|uniprotkb:P10159|uniprotkb:Q16182|uniprotkb:Q7L7L3|uniprotkb:Q7Z4L1|uniprotkb:Q9D0G2|uniprotkb:A8K9A0|uniprotkb:D3DTP2|ensembl:ENSP00000336776|ensembl:ENSP00000390677|ensembl:ENSP00000396073|ensembl:ENSP00000458269|ensembl:ENSP00000459196|ensembl:ENSP00000459611|ensembl:ENSP00000499855|ensembl:ENSP00000499995|ensembl:ENSP00000500414|ensembl:ENSP00000500624|ensembl:ENSP00000500717|ensembl:ENSP00000500847 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:if5a1_human(display_long)|uniprotkb:EIF5A(gene name)|psi-mi:EIF5A(display_short)|uniprotkb:Eukaryotic initiation factor 5A isoform 1(gene name synonym)|uniprotkb:eIF-4D(gene name synonym)|uniprotkb:Rev-binding factor(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE refseq:NP_001137232.1|refseq:NP_001137233.1|refseq:NP_001137234.1|refseq:NP_001961.1|refseq:XP_005256566.1|ensembl:ENSG00000132507(gene)|ensembl:ENSG00000288145(gene)|ensembl:ENST00000336458(transcript)|ensembl:ENST00000416016(transcript)|ensembl:ENST00000419711(transcript)|ensembl:ENST00000571955(transcript)|ensembl:ENST00000573542(transcript)|ensembl:ENST00000576930(transcript)|ensembl:ENST00000672250(transcript)|ensembl:ENST00000672755(transcript)|ensembl:ENST00000673099(transcript)|ensembl:ENST00000673210(transcript)|ensembl:ENST00000673259(transcript)|ensembl:ENST00000673304(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043022"(ribosome binding)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0045905"(positive regulation of translational termination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0098586"(cellular response to virus)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|interpro:IPR001884("Eukaryotic initiation factor 5A hypusine (eIF-5A)")|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR019769|interpro:IPR020189|mint:P63241|rcsb pdb:1FH4|rcsb pdb:3CPF|rcsb pdb:5DLQ|reactome:R-HSA-204626 - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:/smk81DLs+XvrqXmIZpfvdHHauk9606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:Q8NAV1 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-715374|uniprotkb:Q96JW1|uniprotkb:Q9BVZ8|ensembl:ENSP00000257181 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:pr38a_human(display_long)|uniprotkb:PRPF38A(gene name)|psi-mi:PRPF38A(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE refseq:NP_116253.2|ensembl:ENSG00000134748(gene)|ensembl:ENST00000257181(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR005037(PRP38)|interpro:IPR024767|mint:Q8NAV1|rcsb pdb:4RZ9|rcsb pdb:4RZA|rcsb pdb:5F5S|rcsb pdb:5O9Z|rcsb pdb:6AHD|rcsb pdb:7AAV|rcsb pdb:7ABF|rcsb pdb:7ABG|rcsb pdb:7ABI|reactome:R-HSA-72163 - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:Cxehw4X82E4XmwydakoLprmkgmQ9606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:P25490 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-765538|uniprotkb:Q14935|ensembl:ENSP00000262238 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:tyy1_human(display_long)|uniprotkb:Yin and yang 1(gene name synonym)|uniprotkb:Delta transcription factor(gene name synonym)|uniprotkb:NF-E1(gene name synonym)|uniprotkb:YY1(gene name)|psi-mi:YY1(display_short)|uniprotkb:INO80S(gene name synonym)|uniprotkb:INO80 complex subunit S(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE refseq:NP_003394.1|dip:DIP-150N|ensembl:ENSG00000100811(gene)|rcsb pdb:1UBD|rcsb pdb:1ZNM|rcsb pdb:4C5I|reactome:R-HSA-5617472|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8866910|reactome:R-HSA-9018519|ensembl:ENST00000262238(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006403"(RNA localization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010225"(response to UV-C)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034696"(response to prostaglandin F)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048468"(cell development)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0051276"(chromosome organization)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017114(Transcription factor yin and yang)|interpro:IPR036236|mint:P25490 - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:OncFlxfcbNZGN68Sk39CRh9oQHc9606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:P11387 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-876302|ensembl:ENSP00000354522|uniprotkb:Q15610|uniprotkb:Q5TFY3|uniprotkb:Q9UJN0|uniprotkb:O43256|uniprotkb:Q12855|uniprotkb:Q12856|uniprotkb:A8KA78|uniprotkb:E1P5W3 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:top1_human(display_long)|uniprotkb:DNA topoisomerase I(gene name synonym)|uniprotkb:TOP1(gene name)|psi-mi:TOP1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE ensembl:ENSG00000198900(gene)|ensembl:ENST00000361337(transcript)|go:"GO:0000932"(P-body)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006265"(DNA topological change)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007623"(circadian rhythm)|go:"GO:0012501"(programmed cell death)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032922"(circadian regulation of gene expression)|refseq:NP_003277.1|dip:DIP-36356N|go:"GO:0032993"(protein-DNA complex)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042493"|go:"GO:0043204"(perikaryon)|go:"GO:0097100"(supercoiled DNA binding)|interpro:IPR001631(DNA topoisomerase I, C-terminal)|interpro:IPR008336(DNA topoisomerase I, DNA binding, eukaryotic-type)|interpro:IPR011010(DNA breaking-rejoining enzyme, catalytic core)|interpro:IPR013030(DNA topoisomerase I, DNA binding, mixed alpha/beta motif, eukaryotic-type)|interpro:IPR013034(DNA topoisomerase I, DNA binding, alpha helical motif, eukaryotic-type)|interpro:IPR013499(DNA topoisomerase I, C-terminal, eukaryotic-type)|interpro:IPR013500(DNA topoisomerase I, catalytic core, eukaryotic-type)|interpro:IPR014711(DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type)|interpro:IPR014727(DNA topoisomerase I, catalytic core, alpha/beta subdomain, eukaryotic-type)|interpro:IPR018521|interpro:IPR025834|interpro:IPR036202|mint:P11387|rcsb pdb:1A31|rcsb pdb:1A35|rcsb pdb:1A36|rcsb pdb:1EJ9|rcsb pdb:1K4S|rcsb pdb:1K4T|rcsb pdb:1LPQ|rcsb pdb:1NH3|rcsb pdb:1R49|rcsb pdb:1RR8|rcsb pdb:1RRJ|rcsb pdb:1SC7|rcsb pdb:1SEU|rcsb pdb:1T8I|rcsb pdb:1TL8|reactome:R-HSA-4615885 - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:kB+3PVybgNp2mtOmDa7x8sygFuU9606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:Q7Z417 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-1210753|intact:EBI-10172018|uniprotkb:A1L3A7|uniprotkb:Q9P2M5|uniprotkb:A1L3A6|ensembl:ENSP00000225388 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:nufp2_human(display_long)|uniprotkb:NUFIP2(gene name)|psi-mi:NUFIP2(display_short)|uniprotkb:KIAA1321(gene name synonym)|uniprotkb:PIG1(orf name)|uniprotkb:FMRP-interacting protein 2(gene name synonym)|uniprotkb:82 kDa FMRP-interacting protein(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 1 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE refseq:NP_065823.1|dip:DIP-29023N|ensembl:ENSG00000108256(gene)|ensembl:ENST00000225388(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR032747|mint:Q7Z417 - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:zdbkRisveP+8g70umfbEPHTnAgk9606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:Q86XP3 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-722353|uniprotkb:A6NML1|uniprotkb:O75619|uniprotkb:Q68G51|uniprotkb:Q96BK1|uniprotkb:Q96HR7|uniprotkb:Q9Y3V8|uniprotkb:A8KA43|intact:EBI-2555393|ensembl:ENSP00000374574|ensembl:ENSP00000463561|ensembl:ENSP00000464050 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:ddx42_human(display_long)|uniprotkb:DEAD box protein 42(gene name synonym)|uniprotkb:Splicing factor 3B-associated 125 kDa protein(gene name synonym)|uniprotkb:RNA helicase-related protein(gene name synonym)|uniprotkb:RNA helicase-like protein(gene name synonym)|uniprotkb:SF3b DEAD box protein(gene name synonym)|uniprotkb:DDX42(gene name)|psi-mi:DDX42(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE refseq:NP_031398.2|refseq:NP_987095.1|refseq:XP_006721720.1|refseq:XP_016879600.1|ensembl:ENSG00000198231(gene)|ensembl:ENST00000389924(transcript)|ensembl:ENST00000578681(transcript)|ensembl:ENST00000583590(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008104"(protein localization)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q86XP3|reactome:R-HSA-72163|reactome:R-HSA-72165 - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:3vZn92rr6cO8qSZJdyq1fguSc489606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:P48730 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-751621|uniprotkb:Q96KZ6|uniprotkb:Q9BTN5|uniprotkb:A2I2P2|ensembl:ENSP00000324464 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:kc1d_human(display_long)|uniprotkb:CSNK1D(gene name)|psi-mi:CSNK1D(display_short)|uniprotkb:HCKID(gene name synonym)|uniprotkb:Tau-protein kinase CSNK1D(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE refseq:NP_001884.2|refseq:NP_620693.1|dip:DIP-39735N|ensembl:ENSG00000141551(gene)|ensembl:ENST00000314028(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005876"(spindle microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034067"(protein localization to Golgi apparatus)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043005"(neuron projection)|go:"GO:0045296"(cadherin binding)|go:"GO:0048208"(COPII vesicle coating)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1905426"(positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000052"(positive regulation of non-canonical Wnt signaling pathway)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P48730|rcsb pdb:3UYS|rcsb pdb:3UYT|rcsb pdb:3UZP|rcsb pdb:4HGT|rcsb pdb:4HNF|rcsb pdb:4KB8|rcsb pdb:4KBA|rcsb pdb:4KBC|rcsb pdb:4KBK|rcsb pdb:4TN6|rcsb pdb:4TW9|rcsb pdb:4TWC|rcsb pdb:5IH4|rcsb pdb:5IH5|rcsb pdb:5IH6|rcsb pdb:5MQV|rcsb pdb:5OKT|rcsb pdb:5W4W|rcsb pdb:6F1W|rcsb pdb:6F26|rcsb pdb:6GZM|rcsb pdb:6HMP|rcsb pdb:6HMR|rcsb pdb:6PXN|rcsb pdb:6PXO|rcsb pdb:6PXP|rcsb pdb:6RCG|rcsb pdb:6RCH|rcsb pdb:6RU6|rcsb pdb:6RU7|rcsb pdb:6RU8|reactome:R-HSA-204005|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-400253|reactome:R-HSA-5620912|reactome:R-HSA-6791226|reactome:R-HSA-8854518 - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:Rz5aON17Bfduv29izmgHa/FR1/49606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:O43809 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-355720|uniprotkb:Q6IB85|uniprotkb:Q6NE84|ensembl:ENSP00000300291 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:cpsf5_human(display_long)|uniprotkb:NUDT21(gene name)|psi-mi:NUDT21(display_short)|uniprotkb:CFIM25(gene name synonym)|uniprotkb:CPSF25(gene name synonym)|uniprotkb:CPSF5(gene name synonym)|uniprotkb:Cleavage and polyadenylation specificity factor 25 kDa subunit(gene name synonym)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 21(gene name synonym)|uniprotkb:Cleavage factor Im complex 25 kDa subunit(gene name synonym)|uniprotkb:Nudix hydrolase 21(gene name synonym)|uniprotkb:Pre-mRNA cleavage factor Im 68 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE refseq:NP_008937.1|ensembl:ENSG00000167005(gene)|ensembl:ENST00000300291(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0005849"(mRNA cleavage factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0006397"(mRNA processing)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0031439"(positive regulation of mRNA cleavage)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035925"(mRNA 3'-UTR AU-rich region binding)|go:"GO:0042382"(paraspeckles)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051290"(protein heterotetramerization)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|go:"GO:0110104"(mRNA alternative polyadenylation)|go:"GO:1900365"(positive regulation of mRNA polyadenylation)|go:"GO:1990120"(messenger ribonucleoprotein complex assembly)|go:"GO:2000738"(positive regulation of stem cell differentiation)|go:"GO:2000975"(positive regulation of pro-B cell differentiation)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR016706(Cleavage and polyadenylation specificity factor, 25 kDa subunit)|mint:O43809|rcsb pdb:2CL3|rcsb pdb:2J8Q|rcsb pdb:3BAP|rcsb pdb:3BHO|rcsb pdb:3MDG|rcsb pdb:3MDI|rcsb pdb:3N9U|rcsb pdb:3P5T|rcsb pdb:3P6Y|rcsb pdb:3Q2S|rcsb pdb:3Q2T|rcsb pdb:5R4P|rcsb pdb:5R4Q|rcsb pdb:5R4R|rcsb pdb:5R4S|rcsb pdb:5R4T|rcsb pdb:5R4U|rcsb pdb:5R64|rcsb pdb:5R65|rcsb pdb:5R66|rcsb pdb:5R67|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|dip:DIP-42502N - - comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:Acad4mYVuS+Eox+X2CH8PYUkGAA9606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:Q9H0G5 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-5464397|uniprotkb:Q6FI71|ensembl:ENSP00000247026 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:nsrp1_human(display_long)|uniprotkb:NSRP1(gene name)|psi-mi:NSRP1(display_short)|uniprotkb:CCDC55(gene name synonym)|uniprotkb:NSRP70(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 55(gene name synonym)|uniprotkb:Nuclear speckle-related protein 70(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE refseq:NP_115517.1|refseq:NP_001248396.1|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0032502"(developmental process)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR018612|interpro:IPR042816|mint:Q9H0G5|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000126653(gene)|ensembl:ENST00000247026(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus) - - comment:"author score: 27" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:Hp8MjUsGzGZWl+Y/zyzkOxjnLc49606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:P30533 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-715927|uniprotkb:Q2M310|uniprotkb:Q53HQ3|uniprotkb:Q53HS6|uniprotkb:D3DVR9|ensembl:ENSP00000497444 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:amrp_human(display_long)|uniprotkb:Low density lipoprotein receptor-related protein-associated protein 1(gene name synonym)|uniprotkb:LRPAP1(gene name)|psi-mi:LRPAP1(display_short)|uniprotkb:A2MRAP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE refseq:NP_002328.1|ensembl:ENSG00000163956(gene)|ensembl:ENST00000650182(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008201"(heparin binding)|go:"GO:0009986"(cell surface)|go:"GO:0010916"(negative regulation of very-low-density lipoprotein particle clearance)|go:"GO:0012505"(endomembrane system)|go:"GO:0031904"(endosome lumen)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0035473"(lipase binding)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0048237"(rough endoplasmic reticulum lumen)|go:"GO:0048259"(regulation of receptor-mediated endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070326"(very-low-density lipoprotein particle receptor binding)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1900116"(extracellular negative regulation of signal transduction)|go:"GO:1900222"(negative regulation of amyloid-beta clearance)|go:"GO:1900223"(positive regulation of amyloid-beta clearance)|interpro:IPR009066(Alpha-2-macroglobulin receptor-associated protein, domain 1)|interpro:IPR010483(Alpha-2-macroglobulin RAP, C-terminal)|interpro:IPR036744|interpro:IPR037999|interpro:IPR038001|interpro:IPR038003|mint:P30533|rcsb pdb:1LRE|rcsb pdb:1NRE|rcsb pdb:1OP1|rcsb pdb:1OV2|rcsb pdb:2FCW|rcsb pdb:2FTU|rcsb pdb:2FYL|rcsb pdb:2P01|rcsb pdb:2P03|dip:DIP-39355N - - comment:"author score: 27" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:TIbL+P1GW4op4Qawa4lpg8iXUaQ9606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:Q7L2J0 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-2371983|uniprotkb:Q9NPD4|uniprotkb:B3KP86|uniprotkb:D6W5V7|ensembl:ENSP00000308546 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:mepce_human(display_long)|uniprotkb:MEPCE(gene name)|psi-mi:MEPCE(display_short)|uniprotkb:BCDIN3(gene name synonym)|uniprotkb:Bicoid-interacting protein 3 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE refseq:XP_011514712.1|refseq:NP_001181919.1|refseq:NP_001181920.1|refseq:NP_001181921.1|refseq:NP_062552.2|ensembl:ENSG00000146834(gene)|ensembl:ENST00000310512(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001510"(RNA methylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0008171"(O-methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0016073"(snRNA metabolic process)|go:"GO:0017069"(snRNA binding)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0040031"(snRNA modification)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1905382"(positive regulation of snRNA transcription by RNA polymerase II)|go:"GO:1990276"(RNA 5'-methyltransferase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR010675(Bicoid-interacting 3)|interpro:IPR024160|interpro:IPR025714|interpro:IPR029063|interpro:IPR039772|mint:Q7L2J0|rcsb pdb:5UNA|rcsb pdb:6DCB|rcsb pdb:6DCC - - comment:"author score: 31" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:VGhJoO3FD7nsJPVSBsKuKsPJzEM9606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:Q07065 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-702400|uniprotkb:Q504S5|uniprotkb:Q53ES6|ensembl:ENSP00000367265 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:ckap4_human(display_long)|uniprotkb:CKAP4(gene name)|psi-mi:CKAP4(display_short)|uniprotkb:63-kDa cytoskeleton-linking membrane protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE refseq:NP_006816.2|ensembl:ENSG00000136026(gene)|ensembl:ENST00000378026(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042599"(lamellar body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR028428|mint:Q07065|reactome:R-HSA-381426|reactome:R-HSA-5683826|reactome:R-HSA-6798695|reactome:R-HSA-8957275|reactome:R-HSA-9696264|reactome:R-HSA-9696270 - - comment:"author score: 31" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:Q1hrxqh5k4Myf7J0To8Ecm/xxs49606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P23497 uniprotkb:Q8WUA2 intact:EBI-751145|uniprotkb:E9PH61|uniprotkb:O75450|uniprotkb:Q13343|uniprotkb:Q96F70|uniprotkb:Q96T24|uniprotkb:Q96T95|uniprotkb:Q9NP33|uniprotkb:Q9UE32|uniprotkb:Q8TE34|ensembl:ENSP00000264052|uniprotkb:B4DDX5|uniprotkb:B8ZZD8|uniprotkb:F8WFE2|uniprotkb:E7EUA7 intact:EBI-2513119|ensembl:ENSP00000253329|uniprotkb:B2RD34|uniprotkb:Q7Z3Q5 psi-mi:sp100_human(display_long)|uniprotkb:Nuclear dot-associated Sp100 protein(gene name synonym)|uniprotkb:Speckled 100 kDa(gene name synonym)|uniprotkb:SP100(gene name)|psi-mi:SP100(display_short) psi-mi:ppil4_human(display_long)|uniprotkb:PPIL4(gene name)|psi-mi:PPIL4(display_short)|uniprotkb:Cyclophilin-like protein PPIL4(gene name synonym)|uniprotkb:Rotamase PPIL4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485215|imex:IM-26985-583 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001073860.1|refseq:NP_001193630.1|refseq:NP_001193631.1|refseq:NP_001193632.1|refseq:NP_001193633.1|refseq:NP_003104.2|ensembl:ENSG00000067066(gene)|ensembl:ENST00000264052(transcript)|dip:DIP-5983N|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019900"(kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032897"(negative regulation of viral transcription)|go:"GO:0034097"(response to cytokine)|go:"GO:0034340"(response to type I interferon)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045185"(maintenance of protein location)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051271"(negative regulation of cellular component movement)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1902044"(regulation of Fas signaling pathway)|interpro:IPR000770(SAND)|interpro:IPR004865(Sp100)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR010919(SAND-like)|interpro:IPR036910|interpro:IPR043563|mint:P23497|rcsb pdb:1H5P|rcsb pdb:4PTB|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5PWE|rcsb pdb:5PWF|rcsb pdb:5PWG|rcsb pdb:5PWH|rcsb pdb:5PWI|rcsb pdb:5PWJ|rcsb pdb:5PWK|rcsb pdb:5PWL|rcsb pdb:5PWM|rcsb pdb:5PWN|rcsb pdb:5PWO|rcsb pdb:5PWP|rcsb pdb:5PWQ|rcsb pdb:5PWR|rcsb pdb:5PWS|rcsb pdb:5PWT|rcsb pdb:5PWU|rcsb pdb:5PWV|rcsb pdb:5PWW|rcsb pdb:5PWX|rcsb pdb:5PWY|rcsb pdb:5PWZ|rcsb pdb:5PX0|rcsb pdb:5PX1|rcsb pdb:5PX2|rcsb pdb:5PX3|rcsb pdb:5PX4|rcsb pdb:5PX5|rcsb pdb:5PX6|rcsb pdb:5PX7|rcsb pdb:5PX8|rcsb pdb:5PX9|rcsb pdb:5PXA|rcsb pdb:5PXB|rcsb pdb:5PXC|rcsb pdb:5PXD|rcsb pdb:5PXE|rcsb pdb:5PXF|rcsb pdb:5PXG|rcsb pdb:5PXH|rcsb pdb:5PXI|rcsb pdb:5PXJ|rcsb pdb:5PXK|rcsb pdb:5PXL|rcsb pdb:5PXM|rcsb pdb:5PXN|rcsb pdb:5PXO|rcsb pdb:5PXP|rcsb pdb:5PXQ|rcsb pdb:5PXR|rcsb pdb:5PXS|rcsb pdb:5PXT|rcsb pdb:5PXU|rcsb pdb:5PXV|rcsb pdb:5PXW|rcsb pdb:5PXX|rcsb pdb:5PXY|rcsb pdb:5PXZ|rcsb pdb:5PY0|rcsb pdb:5PY1|rcsb pdb:5PY2|rcsb pdb:5PY3|rcsb pdb:5PY4|rcsb pdb:5PY5|rcsb pdb:5PY6|rcsb pdb:5PY7|rcsb pdb:5PY8|rcsb pdb:5PY9|rcsb pdb:5PYA|rcsb pdb:5PYB|rcsb pdb:5PYC|rcsb pdb:5PYD|rcsb pdb:5PYE|rcsb pdb:5PYF|rcsb pdb:5PYG|rcsb pdb:5PYH|rcsb pdb:5PYI|rcsb pdb:5PYJ|rcsb pdb:5PYK|rcsb pdb:5PYL|rcsb pdb:5PYM|rcsb pdb:5PYN|rcsb pdb:5PYO|rcsb pdb:5PYP|rcsb pdb:5PYQ|rcsb pdb:5PYR|rcsb pdb:5PYS|rcsb pdb:5PYT|rcsb pdb:5PYU|rcsb pdb:5PYV|rcsb pdb:5PYW|rcsb pdb:5PYX|rcsb pdb:5PYY|rcsb pdb:5PYZ|rcsb pdb:5PZ0|rcsb pdb:5PZ1|rcsb pdb:5PZ2|rcsb pdb:5PZ3|rcsb pdb:5PZ4|rcsb pdb:5PZ5|rcsb pdb:5PZ6|rcsb pdb:5PZ7|rcsb pdb:5PZ8|rcsb pdb:5PZ9|rcsb pdb:5PZA|rcsb pdb:5PZB|rcsb pdb:5PZC|rcsb pdb:5PZD|rcsb pdb:5PZF|rcsb pdb:5PZG|rcsb pdb:5PZH|rcsb pdb:5PZI|rcsb pdb:5PZJ|rcsb pdb:6G5N|rcsb pdb:6G5P|reactome:R-HSA-3108214|reactome:R-HSA-877300|rcsb pdb:5PZE go:"GO:1901407"(regulation of phosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR029000|interpro:IPR035538|interpro:IPR035542|interpro:IPR035979|mint:Q8WUA2|reactome:R-HSA-72163|go:"GO:0005829"(cytosol)|ensembl:ENSG00000131013(gene)|ensembl:ENST00000253329(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|refseq:NP_624311.1 - - comment:"author score: 31" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:+rzb0oseufnoLe2QXNCvZlV89x89606 rogid:kxM/VRcLUG5M5FAlHuuAKRBKrd89606 rigid:tQWs9nMedYYqK/WQimEnliauxDM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N0Z3 uniprotkb:O15553 intact:EBI-2361917|uniprotkb:Q8WUX6|uniprotkb:D3DN72|intact:EBI-28978711|ensembl:ENSP00000295872 intact:EBI-7644532|ensembl:ENSP00000219596|uniprotkb:D3DUC0|uniprotkb:F5H0Q3|uniprotkb:Q3MJ84|intact:MINT-206922|uniprotkb:Q96PN5|uniprotkb:Q96PN4 psi-mi:spice_human(display_long)|uniprotkb:CCDC52(gene name synonym)|uniprotkb:SPICE(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 52(gene name synonym)|uniprotkb:Spindle and centriole-associated protein(gene name synonym)|uniprotkb:SPICE1(gene name)|psi-mi:SPICE1(display_short) psi-mi:mefv_human(display_long)|uniprotkb:MEFV(gene name)|psi-mi:MEFV(display_short)|uniprotkb:MEF(gene name synonym)|uniprotkb:Marenostrin(gene name synonym)|uniprotkb:TRIM20(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485401|imex:IM-26985-139 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_653319.1|ensembl:ENSP00000295872|refseq:NP_001318007.1|refseq:XP_016861267.1|refseq:NP_001318008.1|ensembl:ENSG00000163611(gene)|ensembl:ENST00000295872(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR031387|mint:Q8N0Z3 ensembl:ENSG00000103313(gene)|ensembl:ENST00000219596(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006954"(inflammatory response)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030027"(lamellipodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032651"(regulation of interleukin-1 beta production)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0032695"(negative regulation of interleukin-12 production)|go:"GO:0034341"(response to interferon-gamma)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071641"(negative regulation of macrophage inflammatory protein 1 alpha production)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1900226"(negative regulation of NLRP3 inflammasome complex assembly)|go:"GO:1904270"(pyroptosome complex assembly)|go:"GO:2001056"(positive regulation of cysteine-type endopeptidase activity)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR004020(Pyrin)|interpro:IPR006574(SPRY-associated)|interpro:IPR011029(DEATH-like)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR028841|interpro:IPR043136|mint:O15553|rcsb pdb:2MPC|rcsb pdb:2WL1|rcsb pdb:4CG4|reactome:R-HSA-844456|reactome:R-HSA-9660826|refseq:NP_000234.1|refseq:NP_001185465.1|dip:DIP-41878N - - function:"Defects in MEFV are the cause of familial Mediterranean fever autosomal recessive (ARFMF) [MIM:249100]. ARFMF is an inherited disorder characterized by recurrent episodic fever, serosal inflammation and pain in the abdomen, chest or joints. ARFMF is frequently complicated by amyloidosis, which leads to renal failure and can be prophylactically treated with colchicine. ARFMF primarily affects ancestral ethnic groups living around the Mediterranean basin: North African Jews, Armenians, Arabs and Turks. The disease is also distributed in other populations including Greeks, Cypriots, Italians and Spanish, although at a lower prevalence"|function:Probably controls the inflammatory response in myelomonocytic cells at the level of the cytoskeleton organization|comment:mint|function:"Defects in MEFV are the cause of familial Mediterranean fever autosomal dominant (ADFMF) [MIM:134610]. ADFMF is characterized by periodic fever, serosal inflammation and pain in the abdomen, chest or joints as seen also in the autosomal recessive form of the disease. It is associated with renal amyloidosis and characterized by colchicine unresponsiveness"|comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Ogv5G3kQP2liovo9dVap83bif2M9606 rogid:sHcSUiMBa8fe0bjgGhgAQcFjNFQ9606 rigid:i0vtPzQoBKsmXRkRIzWJpGVag68 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N0Z3 uniprotkb:P67809 intact:EBI-2361917|uniprotkb:Q8WUX6|uniprotkb:D3DN72|intact:EBI-28978711|ensembl:ENSP00000295872 intact:EBI-354065|uniprotkb:P16990|uniprotkb:P16991|uniprotkb:Q14972|uniprotkb:Q15325|uniprotkb:Q5FVF0|ensembl:ENSP00000361626 psi-mi:spice_human(display_long)|uniprotkb:CCDC52(gene name synonym)|uniprotkb:SPICE(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 52(gene name synonym)|uniprotkb:Spindle and centriole-associated protein(gene name synonym)|uniprotkb:SPICE1(gene name)|psi-mi:SPICE1(display_short) psi-mi:ybox1_human(display_long)|uniprotkb:YBX1(gene name)|psi-mi:YBX1(display_short)|uniprotkb:YB1(gene name synonym)|uniprotkb:NSEP1(gene name synonym)|uniprotkb:Y-box transcription factor(gene name synonym)|uniprotkb:CCAAT-binding transcription factor I subunit A(gene name synonym)|uniprotkb:Enhancer factor I subunit A(gene name synonym)|uniprotkb:DNA-binding protein B(gene name synonym)|uniprotkb:Nuclease-sensitive element-binding protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485401|imex:IM-26985-139 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_653319.1|ensembl:ENSP00000295872|refseq:NP_001318007.1|refseq:XP_016861267.1|refseq:NP_001318008.1|ensembl:ENSG00000163611(gene)|ensembl:ENST00000295872(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR031387|mint:Q8N0Z3 refseq:NP_004550.2|dip:DIP-29405N|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990428"(miRNA transport)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P67809|rcsb pdb:1H95|rcsb pdb:5YTS|rcsb pdb:5YTT|rcsb pdb:5YTV|rcsb pdb:5YTX|rcsb pdb:6A6L|rcsb pdb:6KTC|rcsb pdb:6KUG|rcsb pdb:6LMR|rcsb pdb:6LMS|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-9017802|ensembl:ENSG00000065978(gene)|ensembl:ENST00000321358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0008544"(epidermis development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035198"(miRNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050658"(RNA transport)|go:"GO:0051020"(GTPase binding)|go:"GO:0051031"(tRNA transport)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding) - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Ogv5G3kQP2liovo9dVap83bif2M9606 rogid:0/mAXOzokPlDByFFzGTP8bp9nqo9606 rigid:i0vtPzQoBKsmXRkRIzWJpGVag68 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N0Z3 uniprotkb:Q9BT25 intact:EBI-2361917|uniprotkb:Q8WUX6|uniprotkb:D3DN72|intact:EBI-28978711|ensembl:ENSP00000295872 intact:EBI-2558143|uniprotkb:B4DJA7|uniprotkb:Q86WF0|uniprotkb:Q49AC4|intact:EBI-2562724|uniprotkb:Q96FX3|uniprotkb:C9JBZ4|intact:EBI-11024560|ensembl:ENSP00000253669 psi-mi:spice_human(display_long)|uniprotkb:CCDC52(gene name synonym)|uniprotkb:SPICE(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 52(gene name synonym)|uniprotkb:Spindle and centriole-associated protein(gene name synonym)|uniprotkb:SPICE1(gene name)|psi-mi:SPICE1(display_short) psi-mi:haus8_human(display_long)|uniprotkb:HICE1(gene name synonym)|uniprotkb:HEC1/NDC80-interacting centrosome-associated protein 1(gene name synonym)|uniprotkb:Sarcoma antigen NY-SAR-48(gene name synonym)|uniprotkb:HAUS8(gene name)|psi-mi:HAUS8(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485401|imex:IM-26985-139 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_653319.1|ensembl:ENSP00000295872|refseq:NP_001318007.1|refseq:XP_016861267.1|refseq:NP_001318008.1|ensembl:ENSG00000163611(gene)|ensembl:ENST00000295872(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR031387|mint:Q8N0Z3 refseq:NP_219485.1|refseq:NP_001011699.1|dip:DIP-48834N|ensembl:ENSG00000131351(gene)|ensembl:ENST00000253669(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005880"(nuclear microtubule)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|mint:Q9BT25|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Ogv5G3kQP2liovo9dVap83bif2M9606 rogid:q+J6qqmCxKWrUiWL50GtzEq9+AM9606 rigid:i0vtPzQoBKsmXRkRIzWJpGVag68 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N0Z3 uniprotkb:Q68CZ6 intact:EBI-2361917|uniprotkb:Q8WUX6|uniprotkb:D3DN72|intact:EBI-28978711|ensembl:ENSP00000295872 intact:EBI-2558217|uniprotkb:Q8TAZ5|uniprotkb:O43606|uniprotkb:Q9BTJ9|ensembl:ENSP00000243706|ensembl:ENSP00000500512|ensembl:ENSP00000392903|uniprotkb:B4DF64 psi-mi:spice_human(display_long)|uniprotkb:CCDC52(gene name synonym)|uniprotkb:SPICE(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 52(gene name synonym)|uniprotkb:Spindle and centriole-associated protein(gene name synonym)|uniprotkb:SPICE1(gene name)|psi-mi:SPICE1(display_short) psi-mi:haus3_human(display_long)|uniprotkb:HAUS3(gene name)|psi-mi:HAUS3(display_short)|uniprotkb:C4orf15(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485401|imex:IM-26985-139 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_653319.1|ensembl:ENSP00000295872|refseq:NP_001318007.1|refseq:XP_016861267.1|refseq:NP_001318008.1|ensembl:ENSG00000163611(gene)|ensembl:ENST00000295872(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR031387|mint:Q8N0Z3 refseq:NP_078787.2|ensembl:ENSG00000214367(gene)|ensembl:ENST00000243706(transcript)|ensembl:ENST00000443786(transcript)|ensembl:ENST00000672739(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0045171"(intercellular bridge)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:0072686"(mitotic spindle)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR026206|interpro:IPR032733|mint:Q68CZ6|rcsb pdb:6PTB|rcsb pdb:6PTE|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|refseq:NP_001290072.1|dip:DIP-48832N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Ogv5G3kQP2liovo9dVap83bif2M9606 rogid:gmjepeLf/EVS51MLKnqrcuGniZA9606 rigid:i0vtPzQoBKsmXRkRIzWJpGVag68 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N0Z3 uniprotkb:O94927 intact:EBI-2361917|uniprotkb:Q8WUX6|uniprotkb:D3DN72|intact:EBI-28978711|ensembl:ENSP00000295872 intact:EBI-2558224|uniprotkb:B2RXK1|uniprotkb:Q6P2P7|uniprotkb:Q96CT8|uniprotkb:Q7L3D5|ensembl:ENSP00000439056 psi-mi:spice_human(display_long)|uniprotkb:CCDC52(gene name synonym)|uniprotkb:SPICE(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 52(gene name synonym)|uniprotkb:Spindle and centriole-associated protein(gene name synonym)|uniprotkb:SPICE1(gene name)|psi-mi:SPICE1(display_short) psi-mi:haus5_human(display_long)|uniprotkb:HAUS5(gene name)|psi-mi:HAUS5(display_short)|uniprotkb:KIAA0841(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485401|imex:IM-26985-139 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_653319.1|ensembl:ENSP00000295872|refseq:NP_001318007.1|refseq:XP_016861267.1|refseq:NP_001318008.1|ensembl:ENSG00000163611(gene)|ensembl:ENST00000295872(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR031387|mint:Q8N0Z3 refseq:NP_056117.1|ensembl:ENSG00000249115(gene)|ensembl:ENST00000203166(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR026215|interpro:IPR029131|mint:O94927|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518|dip:DIP-48831N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Ogv5G3kQP2liovo9dVap83bif2M9606 rogid:ChAZl+X89FxK08LHh2+lYDqQZn09606 rigid:i0vtPzQoBKsmXRkRIzWJpGVag68 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N0Z3 uniprotkb:Q99871 intact:EBI-2361917|uniprotkb:Q8WUX6|uniprotkb:D3DN72|intact:EBI-28978711|ensembl:ENSP00000295872 intact:EBI-395719|uniprotkb:Q96HS8|uniprotkb:Q9NP54|uniprotkb:D3DWT9|intact:EBI-2558192|uniprotkb:B4DUH6|uniprotkb:Q9UFH9|ensembl:ENSP00000359230 psi-mi:spice_human(display_long)|uniprotkb:CCDC52(gene name synonym)|uniprotkb:SPICE(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 52(gene name synonym)|uniprotkb:Spindle and centriole-associated protein(gene name synonym)|uniprotkb:SPICE1(gene name)|psi-mi:SPICE1(display_short) psi-mi:haus7_human(display_long)|uniprotkb:HAUS7(gene name)|psi-mi:HAUS7(display_short)|uniprotkb:26S proteasome-associated UCH37-interacting protein 1(gene name synonym)|uniprotkb:X-linked protein STS1769(gene name synonym)|uniprotkb:UIP1(gene name synonym)|uniprotkb:UCHL5IP(gene name synonym)|uniprotkb:UCHL5-interacting protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485401|imex:IM-26985-139 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_653319.1|ensembl:ENSP00000295872|refseq:NP_001318007.1|refseq:XP_016861267.1|refseq:NP_001318008.1|ensembl:ENSG00000163611(gene)|ensembl:ENST00000295872(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR031387|mint:Q8N0Z3 refseq:NP_059988.3|dip:DIP-32974N|ensembl:ENSG00000213397(gene)|ensembl:ENST00000370211(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007098"(centrosome cycle)|go:"GO:0031996"(thioesterase binding)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070652"(HAUS complex)|go:"GO:1990498"(mitotic spindle microtubule)|interpro:IPR029711|mint:Q99871|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Ogv5G3kQP2liovo9dVap83bif2M9606 rogid:nDQXUt43VCTD0vyH0M8OAsGJbEY9606 rigid:i0vtPzQoBKsmXRkRIzWJpGVag68 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N0Z3 uniprotkb:Q5T1J5 intact:EBI-2361917|uniprotkb:Q8WUX6|uniprotkb:D3DN72|intact:EBI-28978711|ensembl:ENSP00000295872 intact:EBI-5325274 psi-mi:spice_human(display_long)|uniprotkb:CCDC52(gene name synonym)|uniprotkb:SPICE(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 52(gene name synonym)|uniprotkb:Spindle and centriole-associated protein(gene name synonym)|uniprotkb:SPICE1(gene name)|psi-mi:SPICE1(display_short) psi-mi:chch9_human(display_long)|uniprotkb:CHCHD2P9(gene name)|psi-mi:CHCHD2P9(display_short)|uniprotkb:C9orf49(gene name synonym)|uniprotkb:CHCHD9(gene name synonym)|uniprotkb:Coiled-coil-helix-coiled-coil-helix domain-containing 2 pseudogene 9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485401|imex:IM-26985-139 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_653319.1|ensembl:ENSP00000295872|refseq:NP_001318007.1|refseq:XP_016861267.1|refseq:NP_001318008.1|ensembl:ENSG00000163611(gene)|ensembl:ENST00000295872(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR031387|mint:Q8N0Z3 go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|mint:Q5T1J5 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Ogv5G3kQP2liovo9dVap83bif2M9606 rogid:nxLtnxxMIGeGK2oC3BIhcwkacSs9606 rigid:i0vtPzQoBKsmXRkRIzWJpGVag68 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N0Z3 uniprotkb:Q9UBN7 intact:EBI-2361917|uniprotkb:Q8WUX6|uniprotkb:D3DN72|intact:EBI-28978711|ensembl:ENSP00000295872 intact:EBI-301697|uniprotkb:O94975|uniprotkb:Q96CY0|uniprotkb:Q6NT75|uniprotkb:Q7L3E5|ensembl:ENSP00000334061|ensembl:ENSP00000365804|ensembl:ENSP00000496013|ensembl:ENSP00000496046 psi-mi:spice_human(display_long)|uniprotkb:CCDC52(gene name synonym)|uniprotkb:SPICE(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 52(gene name synonym)|uniprotkb:Spindle and centriole-associated protein(gene name synonym)|uniprotkb:SPICE1(gene name)|psi-mi:SPICE1(display_short) psi-mi:hdac6_human(display_long)|uniprotkb:HDAC6(gene name)|psi-mi:HDAC6(display_short)|uniprotkb:KIAA0901(gene name synonym)|uniprotkb:JM21(orf name)|uniprotkb:Tubulin-lysine deacetylase HDAC6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485401|imex:IM-26985-139 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_653319.1|ensembl:ENSP00000295872|refseq:NP_001318007.1|refseq:XP_016861267.1|refseq:NP_001318008.1|ensembl:ENSG00000163611(gene)|ensembl:ENST00000295872(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR031387|mint:Q8N0Z3 go:"GO:0006476"(protein deacetylation)|go:"GO:0006515"(protein quality control for misfolded or incompletely synthesized proteins)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0007026"(negative regulation of microtubule depolymerization)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010727"(negative regulation of hydrogen peroxide metabolic process)|go:"GO:0016234"(inclusion body)|go:"GO:0016235"(aggresome)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0016575"(histone deacetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031252"(cell leading edge)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0005829"(cytosol)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0005874"(microtubule)|go:"GO:0032041"("NAD-dependent histone deacetylase activity (H3-K14 specific)")|go:"GO:0032418"(lysosome localization)|go:"GO:0032984"(protein-containing complex disassembly)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0033558"(protein deacetylase activity)|go:"GO:0034983"(peptidyl-lysine deacetylation)|go:"GO:0005901"(caveola)|go:"GO:0035967"(cellular response to topologically incorrect protein)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042903"(tubulin deacetylase activity)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043162"(ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:0043204"(perikaryon)|go:"GO:0043242"(negative regulation of protein-containing complex disassembly)|go:"GO:0045598"(regulation of fat cell differentiation)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048156"(tau protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSG00000094631(gene)|ensembl:ENST00000334136(transcript)|ensembl:ENST00000376619(transcript)|ensembl:ENST00000643374(transcript)|ensembl:ENST00000644068(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003779"(actin binding)|go:"GO:0004407"(histone deacetylase activity)|go:"GO:0005634"(nucleus)|go:"GO:0048668"(collateral sprouting)|go:"GO:0051354"(negative regulation of oxidoreductase activity)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0051788"(response to misfolded protein)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0060632"(regulation of microtubule-based movement)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0060997"(dendritic spine morphogenesis)|go:"GO:0061734"(parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070840"(dynein complex binding)|go:"GO:0070842"(aggresome assembly)|go:"GO:0048487"(beta-tubulin binding)|reactome:R-HSA-5617833|reactome:R-HSA-8878166|reactome:R-HSA-8940973|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9646399|go:"GO:0070846"(Hsp90 deacetylation)|go:"GO:0070848"(response to growth factor)|go:"GO:0071218"(cellular response to misfolded protein)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:1901300"(positive regulation of hydrogen peroxide-mediated programmed cell death)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:2000273"(positive regulation of signaling receptor activity)|interpro:IPR000286(Histone deacetylase superfamily)|interpro:IPR001607(Zinc finger, UBP-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR023696|interpro:IPR023801|interpro:IPR037138|mint:Q9UBN7|rcsb pdb:3C5K|rcsb pdb:3GV4|rcsb pdb:3PHD|go:"GO:0070845"(polyubiquitinated misfolded protein transport)|rcsb pdb:5B8D|rcsb pdb:5EDU|rcsb pdb:5KH3|rcsb pdb:5KH7|rcsb pdb:5KH9|rcsb pdb:5WBN|rcsb pdb:5WPB|rcsb pdb:6CE6|rcsb pdb:6CE8|rcsb pdb:6CEA|rcsb pdb:6CEC|rcsb pdb:6CED|rcsb pdb:6CEE|rcsb pdb:6CEF|reactome:R-HSA-2122947|reactome:R-HSA-2644606|reactome:R-HSA-2894862|reactome:R-HSA-3371511|reactome:R-HSA-350054|refseq:NP_006035.2|refseq:NP_001308155.1|refseq:NP_001308156.1|refseq:NP_001308157.1|refseq:NP_001308158.1|dip:DIP-27544N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Ogv5G3kQP2liovo9dVap83bif2M9606 rogid:j4lt2D2ZcySF9FFqSlCo3a+Q3VU9606 rigid:i0vtPzQoBKsmXRkRIzWJpGVag68 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N0Z3 uniprotkb:Q99417 intact:EBI-2361917|uniprotkb:Q8WUX6|uniprotkb:D3DN72|intact:EBI-28978711|ensembl:ENSP00000295872 intact:EBI-716185|intact:EBI-2559925|uniprotkb:Q5TA64|uniprotkb:Q96HE2|uniprotkb:B2R4N0|ensembl:ENSP00000380702 psi-mi:spice_human(display_long)|uniprotkb:CCDC52(gene name synonym)|uniprotkb:SPICE(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 52(gene name synonym)|uniprotkb:Spindle and centriole-associated protein(gene name synonym)|uniprotkb:SPICE1(gene name)|psi-mi:SPICE1(display_short) psi-mi:mycbp_human(display_long)|uniprotkb:Associate of Myc 1(gene name synonym)|uniprotkb:MYCBP(gene name)|psi-mi:MYCBP(display_short)|uniprotkb:AMY1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485401|imex:IM-26985-139 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_653319.1|ensembl:ENSP00000295872|refseq:NP_001318007.1|refseq:XP_016861267.1|refseq:NP_001318008.1|ensembl:ENSG00000163611(gene)|ensembl:ENST00000295872(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0046599"(regulation of centriole replication)|go:"GO:0051301"(cell division)|go:"GO:0051310"(metaphase plate congression)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR031387|mint:Q8N0Z3 refseq:NP_036465.2|ensembl:ENSG00000214114(gene)|ensembl:ENST00000397572(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007283"(spermatogenesis)|interpro:IPR026060|mint:Q99417|rcsb pdb:2YY0 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Ogv5G3kQP2liovo9dVap83bif2M9606 rogid:jIStn1A10DDkgTuwVeKpDPJ6tIs9606 rigid:i0vtPzQoBKsmXRkRIzWJpGVag68 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13043 uniprotkb:P50749 intact:EBI-367376|uniprotkb:Q15802|uniprotkb:Q4G156|ensembl:ENSP00000361892|uniprotkb:Q5H982|uniprotkb:Q6PD60|uniprotkb:Q9BR32|uniprotkb:Q9NTZ4|uniprotkb:B2RCR8 intact:EBI-960081|uniprotkb:Q17S06|uniprotkb:Q53HD0|uniprotkb:Q6AHZ2|uniprotkb:A6NIX9|uniprotkb:A8K5Z3|uniprotkb:Q8IZA5|ensembl:ENSP00000368684|ensembl:ENSP00000368710 psi-mi:stk4_human(display_long)|uniprotkb:STK4(gene name)|psi-mi:STK4(display_short)|uniprotkb:MST1(gene name synonym)|uniprotkb:STE20-like kinase MST1(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Krs-2(gene name synonym)|uniprotkb:KRS2(gene name synonym) psi-mi:rasf2_human(display_long)|uniprotkb:RASSF2(gene name)|psi-mi:RASSF2(display_short)|uniprotkb:KIAA0168(gene name synonym)|uniprotkb:CENP-34(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485554|imex:IM-26985-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000101109(gene)|ensembl:ENST00000372806(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001841"(neural tube formation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003157"(endocardium development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|refseq:NP_006273.1|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016604"(nuclear body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|refseq:XP_005260590.1|go:"GO:0060800"(regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024205|interpro:IPR036674|mint:Q13043|rcsb pdb:2JO8|rcsb pdb:3COM|rcsb pdb:4NR2|rcsb pdb:4OH8|rcsb pdb:5TWG|rcsb pdb:5TWH|rcsb pdb:6YAT|reactome:R-HSA-2028269|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051262"(protein tetramerization)|go:"GO:0060215"(primitive hemopoiesis)|dip:DIP-32491N refseq:NP_055552.1|refseq:NP_739580.1|refseq:XP_005260952.1|refseq:XP_016883639.1|refseq:XP_016883640.1|refseq:XP_016883641.1|refseq:XP_016883642.1|ensembl:ENSG00000101265(gene)|ensembl:ENST00000379376(transcript)|ensembl:ENST00000379400(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001501"(skeletal system development)|go:"GO:0001503"(ossification)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0038168"(epidermal growth factor receptor signaling pathway via I-kappaB kinase/NF-kappaB cascade)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046849"(bone remodeling)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050821"(protein stabilization)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|interpro:IPR000159(Ras-association)|interpro:IPR011524(SARAH)|interpro:IPR029071|interpro:IPR033614|interpro:IPR033618|mint:P50749 - - comment:"author score: 85" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Z/Uf9T1T/jGvNFWfAkpSf5cQSWY9606 rogid:rHOuV9DDbLYoQvm4W6RNF3V2fUo9606 rigid:dT/MjO9OKQICF/VLXXs/4vz+N0Q false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13043 uniprotkb:Q9UJZ1 intact:EBI-367376|uniprotkb:Q15802|uniprotkb:Q4G156|ensembl:ENSP00000361892|uniprotkb:Q5H982|uniprotkb:Q6PD60|uniprotkb:Q9BR32|uniprotkb:Q9NTZ4|uniprotkb:B2RCR8 intact:EBI-1044428|ensembl:ENSP00000348886|uniprotkb:O60376|uniprotkb:Q53G29|uniprotkb:Q96FY2|uniprotkb:Q9P042|uniprotkb:D3DRN3|uniprotkb:B4E1K7 psi-mi:stk4_human(display_long)|uniprotkb:STK4(gene name)|psi-mi:STK4(display_short)|uniprotkb:MST1(gene name synonym)|uniprotkb:STE20-like kinase MST1(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Krs-2(gene name synonym)|uniprotkb:KRS2(gene name synonym) psi-mi:stml2_human(display_long)|uniprotkb:EPB72-like protein 2(gene name synonym)|uniprotkb:STOML2(gene name)|psi-mi:STOML2(display_short)|uniprotkb:SLP2(gene name synonym)|uniprotkb:HSPC108(orf name)|uniprotkb:Paraprotein target 7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485554|imex:IM-26985-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000101109(gene)|ensembl:ENST00000372806(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001841"(neural tube formation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003157"(endocardium development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|refseq:NP_006273.1|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016604"(nuclear body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|refseq:XP_005260590.1|go:"GO:0060800"(regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024205|interpro:IPR036674|mint:Q13043|rcsb pdb:2JO8|rcsb pdb:3COM|rcsb pdb:4NR2|rcsb pdb:4OH8|rcsb pdb:5TWG|rcsb pdb:5TWH|rcsb pdb:6YAT|reactome:R-HSA-2028269|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051262"(protein tetramerization)|go:"GO:0060215"(primitive hemopoiesis)|dip:DIP-32491N ensembl:ENSG00000165283(gene)|ensembl:ENST00000356493(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006851"(mitochondrial calcium ion transmembrane transport)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0010876"(lipid localization)|go:"GO:0010918"(positive regulation of mitochondrial membrane potential)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034982"(mitochondrial protein processing)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0035710"(CD4-positive, alpha-beta T cell activation)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:0045121"(membrane raft)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0051020"(GTPase binding)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0090297"(positive regulation of mitochondrial DNA replication)|go:"GO:1900210"(positive regulation of cardiolipin metabolic process)|go:"GO:1901612"(cardiolipin binding)|go:"GO:1990046"(stress-induced mitochondrial fusion)|interpro:IPR001107(Band 7 protein)|interpro:IPR001972(Stomatin)|interpro:IPR032435|interpro:IPR036013|mint:Q9UJZ1|reactome:R-HSA-8949664|refseq:NP_001273960.1|refseq:NP_038470.1|refseq:NP_001273961.1 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Z/Uf9T1T/jGvNFWfAkpSf5cQSWY9606 rogid:VH6uT4ShPg3IpPHbQtaSVXjZAYg9606 rigid:dT/MjO9OKQICF/VLXXs/4vz+N0Q false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13043 uniprotkb:Q8WWW0 intact:EBI-367376|uniprotkb:Q15802|uniprotkb:Q4G156|ensembl:ENSP00000361892|uniprotkb:Q5H982|uniprotkb:Q6PD60|uniprotkb:Q9BR32|uniprotkb:Q9NTZ4|uniprotkb:B2RCR8 intact:EBI-367390|uniprotkb:Q5SY32|uniprotkb:Q8WWV9|uniprotkb:Q8WXF4|uniprotkb:Q9BT99|uniprotkb:A8K1E6|ensembl:ENSP00000462099 psi-mi:stk4_human(display_long)|uniprotkb:STK4(gene name)|psi-mi:STK4(display_short)|uniprotkb:MST1(gene name synonym)|uniprotkb:STE20-like kinase MST1(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Krs-2(gene name synonym)|uniprotkb:KRS2(gene name synonym) psi-mi:rasf5_human(display_long)|uniprotkb:RAPL(gene name synonym)|uniprotkb:RASSF5(gene name)|psi-mi:RASSF5(display_short)|uniprotkb:NORE1(gene name synonym)|uniprotkb:New ras effector 1(gene name synonym)|uniprotkb:Regulator for cell adhesion and polarization enriched in lymphoid tissues(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485554|imex:IM-26985-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000101109(gene)|ensembl:ENST00000372806(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001841"(neural tube formation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003157"(endocardium development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|refseq:NP_006273.1|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016604"(nuclear body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|refseq:XP_005260590.1|go:"GO:0060800"(regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024205|interpro:IPR036674|mint:Q13043|rcsb pdb:2JO8|rcsb pdb:3COM|rcsb pdb:4NR2|rcsb pdb:4OH8|rcsb pdb:5TWG|rcsb pdb:5TWH|rcsb pdb:6YAT|reactome:R-HSA-2028269|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051262"(protein tetramerization)|go:"GO:0060215"(primitive hemopoiesis)|dip:DIP-32491N refseq:NP_872604.1|refseq:NP_872605.1|refseq:NP_872606.1|ensembl:ENSG00000266094(gene)|ensembl:ENST00000579436(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:1900180"(regulation of protein localization to nucleus)|interpro:IPR000159(Ras-association)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011524(SARAH)|interpro:IPR029071|interpro:IPR033614|interpro:IPR033623|mint:Q8WWW0|rcsb pdb:4LGD|rcsb pdb:4OH8|dip:DIP-32490N - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Z/Uf9T1T/jGvNFWfAkpSf5cQSWY9606 rogid:EqQpr1Zt1laHo0Y23CpTVMnl28Y9606 rigid:dT/MjO9OKQICF/VLXXs/4vz+N0Q false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13043 uniprotkb:Q9H4B6 intact:EBI-367376|uniprotkb:Q15802|uniprotkb:Q4G156|ensembl:ENSP00000361892|uniprotkb:Q5H982|uniprotkb:Q6PD60|uniprotkb:Q9BR32|uniprotkb:Q9NTZ4|uniprotkb:B2RCR8 intact:EBI-1017775|uniprotkb:Q6IA58|uniprotkb:Q9H949|uniprotkb:Q9HAK9|uniprotkb:A8K4B8|uniprotkb:D3DSB6|ensembl:ENSP00000324729 psi-mi:stk4_human(display_long)|uniprotkb:STK4(gene name)|psi-mi:STK4(display_short)|uniprotkb:MST1(gene name synonym)|uniprotkb:STE20-like kinase MST1(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Krs-2(gene name synonym)|uniprotkb:KRS2(gene name synonym) psi-mi:sav1_human(display_long)|uniprotkb:SAV1(gene name)|psi-mi:SAV1(display_short)|uniprotkb:WW45(gene name synonym)|uniprotkb:45 kDa WW domain protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485554|imex:IM-26985-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000101109(gene)|ensembl:ENST00000372806(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001841"(neural tube formation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003157"(endocardium development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|refseq:NP_006273.1|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016604"(nuclear body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|refseq:XP_005260590.1|go:"GO:0060800"(regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024205|interpro:IPR036674|mint:Q13043|rcsb pdb:2JO8|rcsb pdb:3COM|rcsb pdb:4NR2|rcsb pdb:4OH8|rcsb pdb:5TWG|rcsb pdb:5TWH|rcsb pdb:6YAT|reactome:R-HSA-2028269|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051262"(protein tetramerization)|go:"GO:0060215"(primitive hemopoiesis)|dip:DIP-32491N refseq:NP_068590.1|ensembl:ENSG00000151748(gene)|ensembl:ENST00000324679(transcript)|go:"GO:0001942"(hair follicle development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0035329"(hippo signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0046332"(SMAD binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060487"(lung epithelial cell differentiation)|go:"GO:0060575"(intestinal epithelial cell differentiation)|go:"GO:0070699"(type II activin receptor binding)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR011524(SARAH)|interpro:IPR030030|interpro:IPR036020|mint:Q9H4B6|rcsb pdb:6AO5|reactome:R-HSA-2028269|dip:DIP-36127N - - comment:"author score: 42" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Z/Uf9T1T/jGvNFWfAkpSf5cQSWY9606 rogid:djvNX49LV19MDK/wNLfLkX2JMxM9606 rigid:dT/MjO9OKQICF/VLXXs/4vz+N0Q false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13043 uniprotkb:Q9NS23 intact:EBI-367376|uniprotkb:Q15802|uniprotkb:Q4G156|ensembl:ENSP00000361892|uniprotkb:Q5H982|uniprotkb:Q6PD60|uniprotkb:Q9BR32|uniprotkb:Q9NTZ4|uniprotkb:B2RCR8 intact:EBI-367363|uniprotkb:B7ZLL1|uniprotkb:Q0VGC6|uniprotkb:O14571|uniprotkb:O60539|uniprotkb:O60710|uniprotkb:Q9HB04|uniprotkb:Q9HB18|uniprotkb:Q9NS22|uniprotkb:Q9UND4|uniprotkb:Q9UND5|intact:EBI-2556435|uniprotkb:Q5TZT2|ensembl:ENSP00000349547 psi-mi:stk4_human(display_long)|uniprotkb:STK4(gene name)|psi-mi:STK4(display_short)|uniprotkb:MST1(gene name synonym)|uniprotkb:STE20-like kinase MST1(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Krs-2(gene name synonym)|uniprotkb:KRS2(gene name synonym) psi-mi:rasf1_human(display_long)|uniprotkb:RASSF1(gene name)|psi-mi:RASSF1(display_short)|uniprotkb:RDA32(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485554|imex:IM-26985-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000101109(gene)|ensembl:ENST00000372806(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001841"(neural tube formation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003157"(endocardium development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|refseq:NP_006273.1|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016604"(nuclear body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|refseq:XP_005260590.1|go:"GO:0060800"(regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024205|interpro:IPR036674|mint:Q13043|rcsb pdb:2JO8|rcsb pdb:3COM|rcsb pdb:4NR2|rcsb pdb:4OH8|rcsb pdb:5TWG|rcsb pdb:5TWH|rcsb pdb:6YAT|reactome:R-HSA-2028269|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051262"(protein tetramerization)|go:"GO:0060215"(primitive hemopoiesis)|dip:DIP-32491N refseq:XP_011531617.1|refseq:XP_011531618.1|refseq:NP_001193886.1|refseq:NP_009113.3|refseq:NP_733830.1|refseq:NP_733831.1|refseq:NP_733832.1|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR000159(Ras-association)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011524(SARAH)|interpro:IPR029071|interpro:IPR033600|interpro:IPR033614|mint:Q9NS23|rcsb pdb:2KZU|ensembl:ENSG00000068028(gene)|ensembl:ENST00000357043(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005874"(microtubule)|go:"GO:0006974"(cellular response to DNA damage stimulus)|dip:DIP-31270N - - comment:"author score: 48" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Z/Uf9T1T/jGvNFWfAkpSf5cQSWY9606 rogid:kMwpeQ92/ax7NZwtEVal0/XilaI9606 rigid:dT/MjO9OKQICF/VLXXs/4vz+N0Q false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13043 uniprotkb:Q13188 intact:EBI-367376|uniprotkb:Q15802|uniprotkb:Q4G156|ensembl:ENSP00000361892|uniprotkb:Q5H982|uniprotkb:Q6PD60|uniprotkb:Q9BR32|uniprotkb:Q9NTZ4|uniprotkb:B2RCR8 intact:EBI-992580|uniprotkb:Q15445|uniprotkb:Q15801|uniprotkb:Q96FM6|uniprotkb:A8K722|ensembl:ENSP00000390500|uniprotkb:B3KYA7 psi-mi:stk4_human(display_long)|uniprotkb:STK4(gene name)|psi-mi:STK4(display_short)|uniprotkb:MST1(gene name synonym)|uniprotkb:STE20-like kinase MST1(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Krs-2(gene name synonym)|uniprotkb:KRS2(gene name synonym) psi-mi:stk3_human(display_long)|uniprotkb:STE20-like kinase MST2(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Krs-1(gene name synonym)|uniprotkb:STK3(gene name)|psi-mi:STK3(display_short)|uniprotkb:MST2(gene name synonym)|uniprotkb:KRS1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485554|imex:IM-26985-67 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000101109(gene)|ensembl:ENST00000372806(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001841"(neural tube formation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003157"(endocardium development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|refseq:NP_006273.1|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016604"(nuclear body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|refseq:XP_005260590.1|go:"GO:0060800"(regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024205|interpro:IPR036674|mint:Q13043|rcsb pdb:2JO8|rcsb pdb:3COM|rcsb pdb:4NR2|rcsb pdb:4OH8|rcsb pdb:5TWG|rcsb pdb:5TWH|rcsb pdb:6YAT|reactome:R-HSA-2028269|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051262"(protein tetramerization)|go:"GO:0060215"(primitive hemopoiesis)|dip:DIP-32491N refseq:NP_001243241.1|refseq:NP_006272.2|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024205|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|interpro:IPR036674|mint:Q13188|rcsb pdb:3WWS|rcsb pdb:4HKD|rcsb pdb:4L0N|rcsb pdb:4LG4|rcsb pdb:4LGD|rcsb pdb:4OH9|rcsb pdb:5BRM|rcsb pdb:5DH3|rcsb pdb:6AO5|rcsb pdb:6AR2|reactome:R-HSA-2028269|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060215"(primitive hemopoiesis)|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0060800"(regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0106311"|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|ensembl:ENSG00000104375(gene)|ensembl:ENST00000419617(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001841"(neural tube formation)|go:"GO:0003157"(endocardium development)|dip:DIP-36128N - - comment:"author score: 377" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Z/Uf9T1T/jGvNFWfAkpSf5cQSWY9606 rogid:slrC4Ax6263chBC1DJygdoExuCc9606 rigid:dT/MjO9OKQICF/VLXXs/4vz+N0Q false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15208 uniprotkb:Q9Y2H1 intact:EBI-458376|ensembl:ENSP00000229812|uniprotkb:Q503A1 intact:EBI-991501|uniprotkb:Q8TBX7|uniprotkb:A8K4U0|uniprotkb:B4E3J8|ensembl:ENSP00000373684 psi-mi:stk38_human(display_long)|uniprotkb:NDR1(gene name synonym)|uniprotkb:STK38(gene name)|psi-mi:STK38(display_short)|uniprotkb:NDR1 protein kinase(gene name synonym)|uniprotkb:Nuclear Dbf2-related kinase 1(gene name synonym) psi-mi:st38l_human(display_long)|uniprotkb:NDR2 protein kinase(gene name synonym)|uniprotkb:Nuclear Dbf2-related kinase 2(gene name synonym)|uniprotkb:STK38L(gene name)|psi-mi:STK38L(display_short)|uniprotkb:KIAA0965(gene name synonym)|uniprotkb:NDR2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485542|imex:IM-26985-439 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000112079(gene)|ensembl:ENST00000229812(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|mint:Q15208|rcsb pdb:1PSB|rcsb pdb:6BXI|reactome:R-HSA-9013418|reactome:R-HSA-9013422|refseq:NP_009202.1|refseq:XP_006715051.1|refseq:XP_006715052.1|refseq:NP_001292031.1 refseq:XP_006719121.1|ensembl:ENSG00000211455(gene)|ensembl:ENST00000389032(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003779"(actin binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0051128"(regulation of cellular component organization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0005524"(ATP binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|mint:Q9Y2H1|rcsb pdb:5XQZ|refseq:NP_055815.1|refseq:XP_011518915.1|refseq:XP_016874525.1 - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:YHzdDrPEH6YdhOXtcnLWArqftck9606 rogid:lKXWdkeLMD/YCxa1oQz9k0aoW3I9606 rigid:tLf8LnwQZ+sgSAvctAl//hoFmI0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15208 uniprotkb:P11473 intact:EBI-458376|ensembl:ENSP00000229812|uniprotkb:Q503A1 intact:EBI-286357|uniprotkb:Q5PSV3|uniprotkb:B2R5Q1|uniprotkb:G3V1V9|ensembl:ENSP00000378734|ensembl:ENSP00000449573 psi-mi:stk38_human(display_long)|uniprotkb:NDR1(gene name synonym)|uniprotkb:STK38(gene name)|psi-mi:STK38(display_short)|uniprotkb:NDR1 protein kinase(gene name synonym)|uniprotkb:Nuclear Dbf2-related kinase 1(gene name synonym) psi-mi:vdr_human(display_long)|uniprotkb:1,25-dihydroxyvitamin D3 receptor(gene name synonym)|uniprotkb:Nuclear receptor subfamily 1 group I member 1(gene name synonym)|uniprotkb:VDR(gene name)|psi-mi:VDR(display_short)|uniprotkb:NR1I1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485542|imex:IM-26985-439 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000112079(gene)|ensembl:ENST00000229812(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|mint:Q15208|rcsb pdb:1PSB|rcsb pdb:6BXI|reactome:R-HSA-9013418|reactome:R-HSA-9013422|refseq:NP_009202.1|refseq:XP_006715051.1|refseq:XP_006715052.1|refseq:NP_001292031.1 refseq:NP_000367.1|refseq:NP_001017535.1|refseq:NP_001017536.1|refseq:XP_006719650.1|refseq:XP_011537022.1|dip:DIP-32624N|ensembl:ENSG00000111424(gene)|ensembl:ENST00000395324(transcript)|ensembl:ENST00000549336(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001501"(skeletal system development)|go:"GO:0003677"(DNA binding)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007595"(lactation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0010980"(positive regulation of vitamin D 24-hydroxylase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0038183"(bile acid signaling pathway)|go:"GO:0038186"(lithocholic acid receptor activity)|go:"GO:0043235"(receptor complex)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046697"(decidualization)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0050892"(intestinal absorption)|go:"GO:0060058"(positive regulation of apoptotic process involved in mammary gland involution)|go:"GO:0060558"(regulation of calcidiol 1-monooxygenase activity)|go:"GO:0060745"(mammary gland branching involved in pregnancy)|go:"GO:0070561"(vitamin D receptor signaling pathway)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1902098"(calcitriol binding)|go:"GO:1902121"(lithocholic acid binding)|interpro:IPR000324(Vitamin D receptor)|interpro:IPR000536(Nuclear hormone receptor, ligand-binding, core)|interpro:IPR001628(Zinc finger, nuclear hormone receptor-type)|interpro:IPR001723(Steroid hormone receptor)|interpro:IPR013088(Zinc finger, NHR/GATA-type)|interpro:IPR035500|interpro:IPR042153|mint:P11473|rcsb pdb:1DB1|rcsb pdb:1IE8|rcsb pdb:1IE9|rcsb pdb:1KB2|rcsb pdb:1KB4|rcsb pdb:1KB6|rcsb pdb:1S0Z|rcsb pdb:1S19|rcsb pdb:1TXI|rcsb pdb:1YNW|rcsb pdb:2HAM|rcsb pdb:2HAR|rcsb pdb:2HAS|rcsb pdb:2HB7|rcsb pdb:2HB8|rcsb pdb:3A2I|rcsb pdb:3A2J|rcsb pdb:3A3Z|rcsb pdb:3A40|rcsb pdb:3A78|rcsb pdb:3AUQ|rcsb pdb:3AUR|rcsb pdb:3AX8|rcsb pdb:3AZ1|rcsb pdb:3AZ2|rcsb pdb:3AZ3|rcsb pdb:3B0T|rcsb pdb:3CS4|rcsb pdb:3CS6|rcsb pdb:3KPZ|rcsb pdb:3M7R|rcsb pdb:3OGT|rcsb pdb:3P8X|rcsb pdb:3TKC|rcsb pdb:3VHW|rcsb pdb:3W0A|rcsb pdb:3W0C|rcsb pdb:3W0Y|rcsb pdb:3WGP|rcsb pdb:3WWR|rcsb pdb:3X31|rcsb pdb:3X36|rcsb pdb:4G2I|rcsb pdb:4ITE|rcsb pdb:4ITF|rcsb pdb:5GT4|rcsb pdb:5V39|rcsb pdb:5YSY|rcsb pdb:5YT2|reactome:R-HSA-196791|reactome:R-HSA-383280|reactome:R-HSA-4090294 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:YHzdDrPEH6YdhOXtcnLWArqftck9606 rogid:7j3KKs/nPSWIKLnb2SZqA+UAysM9606 rigid:tLf8LnwQZ+sgSAvctAl//hoFmI0 false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BXU1 uniprotkb:P60468 intact:EBI-2880195|ensembl:ENSP00000348132|uniprotkb:B7WPP5|uniprotkb:Q6PCD3|uniprotkb:Q9BXH8|uniprotkb:B4DZ06|uniprotkb:C9J4F9 intact:EBI-1788819|uniprotkb:P38390|uniprotkb:P38391|uniprotkb:Q6IBC1|ensembl:ENSP00000223641 psi-mi:stk31_human(display_long)|uniprotkb:STK31(gene name)|psi-mi:STK31(display_short)|uniprotkb:SGK396(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NYD-SPK(gene name synonym)|uniprotkb:Sugen kinase 396(gene name synonym) psi-mi:sc61b_human(display_long)|uniprotkb:SEC61B(gene name)|psi-mi:SEC61B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485524|imex:IM-26985-291 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196335(gene)|ensembl:ENST00000355870(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004518"(nuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002999(Tudor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR035437|mint:Q9BXU1|refseq:NP_113602.2|refseq:NP_116562.2|refseq:NP_001247433.1|refseq:NP_001247434.1 refseq:NP_006799.1|dip:DIP-40997N|ensembl:ENSG00000106803(gene)|ensembl:ENST00000223641(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005784"(Sec61 translocon complex)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006616"(SRP-dependent cotranslational protein targeting to membrane, translocation)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031205"(endoplasmic reticulum Sec complex)|go:"GO:0043022"(ribosome binding)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0048408"(epidermal growth factor binding)|interpro:IPR016482(Preprotein translocase Sec, Sec61-beta subunit, eukarya)|interpro:IPR030671|mint:P60468|rcsb pdb:6W6L|reactome:R-HSA-1236974|reactome:R-HSA-1799339|reactome:R-HSA-9609523 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:KC+aYcEcEHGINDcLf6qtz5EPiGg9606 rogid:hmJI1Sb6h53BUHLoKTSJPyTbPF89606 rigid:ICcRMQznpl52lu33k/HM3WSiDgU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BXU1 uniprotkb:Q96QD9 intact:EBI-2880195|ensembl:ENSP00000348132|uniprotkb:B7WPP5|uniprotkb:Q6PCD3|uniprotkb:Q9BXH8|uniprotkb:B4DZ06|uniprotkb:C9J4F9 intact:EBI-724553|uniprotkb:Q96SL9|uniprotkb:Q9BQI8|uniprotkb:A8MY74|uniprotkb:B2RCB2|uniprotkb:B7Z3R4|uniprotkb:B7Z7V1|uniprotkb:B7Z8I0|uniprotkb:B7ZAJ3|uniprotkb:C9J7P6|uniprotkb:C9JNG6|uniprotkb:C9JTH3|uniprotkb:C9JY50|ensembl:ENSP00000241502 psi-mi:stk31_human(display_long)|uniprotkb:STK31(gene name)|psi-mi:STK31(display_short)|uniprotkb:SGK396(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NYD-SPK(gene name synonym)|uniprotkb:Sugen kinase 396(gene name synonym) psi-mi:uif_human(display_long)|uniprotkb:UIF(gene name synonym)|uniprotkb:FYTTD1(gene name)|psi-mi:FYTTD1(display_short)|uniprotkb:Forty-two-three domain-containing protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485524|imex:IM-26985-291 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196335(gene)|ensembl:ENST00000355870(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004518"(nuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002999(Tudor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR035437|mint:Q9BXU1|refseq:NP_113602.2|refseq:NP_116562.2|refseq:NP_001247433.1|refseq:NP_001247434.1 refseq:NP_001011537.2|refseq:NP_115664.2|ensembl:ENSG00000122068(gene)|ensembl:ENST00000241502(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0016607"(nuclear speck)|interpro:IPR009782(Protein of unknown function DUF1346)|mint:Q96QD9|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856|dip:DIP-62119N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:KC+aYcEcEHGINDcLf6qtz5EPiGg9606 rogid:mMARxli9v/w8ggb5tjd/5hvSxnI9606 rigid:ICcRMQznpl52lu33k/HM3WSiDgU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BXU1 uniprotkb:Q9Y241 intact:EBI-2880195|ensembl:ENSP00000348132|uniprotkb:B7WPP5|uniprotkb:Q6PCD3|uniprotkb:Q9BXH8|uniprotkb:B4DZ06|uniprotkb:C9J4F9 intact:EBI-1051940|uniprotkb:Q9UFZ2|ensembl:ENSP00000319393|ensembl:ENSP00000402160 psi-mi:stk31_human(display_long)|uniprotkb:STK31(gene name)|psi-mi:STK31(display_short)|uniprotkb:SGK396(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NYD-SPK(gene name synonym)|uniprotkb:Sugen kinase 396(gene name synonym) psi-mi:hig1a_human(display_long)|uniprotkb:Hypoxia-inducible gene 1 protein(gene name synonym)|uniprotkb:HIGD1A(gene name)|psi-mi:HIGD1A(display_short)|uniprotkb:HIG1(gene name synonym)|uniprotkb:RCF1 homolog A(gene name synonym)|uniprotkb:HSPC010(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485524|imex:IM-26985-291 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196335(gene)|ensembl:ENST00000355870(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004518"(nuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002999(Tudor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR035437|mint:Q9BXU1|refseq:NP_113602.2|refseq:NP_116562.2|refseq:NP_001247433.1|refseq:NP_001247434.1 refseq:NP_001093138.1|refseq:NP_001093139.1|refseq:NP_054775.2|ensembl:ENSG00000181061(gene)|ensembl:ENST00000321331(transcript)|ensembl:ENST00000418900(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070469"(respirasome)|go:"GO:0097250"(mitochondrial respirasome assembly)|interpro:IPR007667(Hypoxia induced protein conserved region)|mint:Q9Y241|rcsb pdb:2LOM|reactome:R-HSA-1234158 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:KC+aYcEcEHGINDcLf6qtz5EPiGg9606 rogid:xFklQUZRMs1m+6gbSJu2tKVz0Dk9606 rigid:ICcRMQznpl52lu33k/HM3WSiDgU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9BXU1 uniprotkb:Q9NRY5 intact:EBI-2880195|ensembl:ENSP00000348132|uniprotkb:B7WPP5|uniprotkb:Q6PCD3|uniprotkb:Q9BXH8|uniprotkb:B4DZ06|uniprotkb:C9J4F9 intact:EBI-10973142|ensembl:ENSP00000430384|ensembl:ENSP00000430489|ensembl:ENSP00000341597|uniprotkb:Q9H7E0|uniprotkb:B2R8D8 psi-mi:stk31_human(display_long)|uniprotkb:STK31(gene name)|psi-mi:STK31(display_short)|uniprotkb:SGK396(gene name synonym)|uniprotkb:Serine/threonine-protein kinase NYD-SPK(gene name synonym)|uniprotkb:Sugen kinase 396(gene name synonym) psi-mi:f1142_human(display_long)|uniprotkb:FAM114A2(gene name)|psi-mi:FAM114A2(display_short)|uniprotkb:C5orf3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485524|imex:IM-26985-291 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000196335(gene)|ensembl:ENST00000355870(transcript)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0004518"(nuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR002999(Tudor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR035437|mint:Q9BXU1|refseq:NP_113602.2|refseq:NP_116562.2|refseq:NP_001247433.1|refseq:NP_001247434.1 refseq:NP_001304922.1|refseq:NP_001304923.1|refseq:NP_001304924.1|refseq:NP_061161.2|refseq:XP_005268417.1|refseq:XP_005268418.1|refseq:XP_011535842.1|refseq:XP_011535843.1|refseq:XP_011535844.1|ensembl:ENST00000351797(transcript)|ensembl:ENST00000520667(transcript)|ensembl:ENST00000522858(transcript)|go:"GO:0017076"(purine nucleotide binding)|interpro:IPR007998(Protein of unknown function DUF719)|mint:Q9NRY5|reactome:R-HSA-6802952|ensembl:ENSG00000055147(gene)|refseq:XP_016864456.1|refseq:XP_016864457.1 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:KC+aYcEcEHGINDcLf6qtz5EPiGg9606 rogid:HHA13BmHMbBiHCHhfOIKh3511nM9606 rigid:ICcRMQznpl52lu33k/HM3WSiDgU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13188 uniprotkb:P50749 intact:EBI-992580|uniprotkb:Q15445|uniprotkb:Q15801|uniprotkb:Q96FM6|uniprotkb:A8K722|ensembl:ENSP00000390500|uniprotkb:B3KYA7 intact:EBI-960081|uniprotkb:Q17S06|uniprotkb:Q53HD0|uniprotkb:Q6AHZ2|uniprotkb:A6NIX9|uniprotkb:A8K5Z3|uniprotkb:Q8IZA5|ensembl:ENSP00000368684|ensembl:ENSP00000368710 psi-mi:stk3_human(display_long)|uniprotkb:STE20-like kinase MST2(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Krs-1(gene name synonym)|uniprotkb:STK3(gene name)|psi-mi:STK3(display_short)|uniprotkb:MST2(gene name synonym)|uniprotkb:KRS1(gene name synonym) psi-mi:rasf2_human(display_long)|uniprotkb:RASSF2(gene name)|psi-mi:RASSF2(display_short)|uniprotkb:KIAA0168(gene name synonym)|uniprotkb:CENP-34(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485497|imex:IM-26985-585 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001243241.1|refseq:NP_006272.2|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024205|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|interpro:IPR036674|mint:Q13188|rcsb pdb:3WWS|rcsb pdb:4HKD|rcsb pdb:4L0N|rcsb pdb:4LG4|rcsb pdb:4LGD|rcsb pdb:4OH9|rcsb pdb:5BRM|rcsb pdb:5DH3|rcsb pdb:6AO5|rcsb pdb:6AR2|reactome:R-HSA-2028269|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060215"(primitive hemopoiesis)|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0060800"(regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0106311"|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|ensembl:ENSG00000104375(gene)|ensembl:ENST00000419617(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001841"(neural tube formation)|go:"GO:0003157"(endocardium development)|dip:DIP-36128N refseq:NP_055552.1|refseq:NP_739580.1|refseq:XP_005260952.1|refseq:XP_016883639.1|refseq:XP_016883640.1|refseq:XP_016883641.1|refseq:XP_016883642.1|ensembl:ENSG00000101265(gene)|ensembl:ENST00000379376(transcript)|ensembl:ENST00000379400(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001501"(skeletal system development)|go:"GO:0001503"(ossification)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0038168"(epidermal growth factor receptor signaling pathway via I-kappaB kinase/NF-kappaB cascade)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0045667"(regulation of osteoblast differentiation)|go:"GO:0045670"(regulation of osteoclast differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046849"(bone remodeling)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050821"(protein stabilization)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|interpro:IPR000159(Ras-association)|interpro:IPR011524(SARAH)|interpro:IPR029071|interpro:IPR033614|interpro:IPR033618|mint:P50749 - - comment:"author score: 93" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:slrC4Ax6263chBC1DJygdoExuCc9606 rogid:rHOuV9DDbLYoQvm4W6RNF3V2fUo9606 rigid:Mda+iwWrR8+UCIMOZvFI/X2uEro false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13188 uniprotkb:Q49A26 intact:EBI-992580|uniprotkb:Q15445|uniprotkb:Q15801|uniprotkb:Q96FM6|uniprotkb:A8K722|ensembl:ENSP00000390500|uniprotkb:B3KYA7 intact:EBI-2804292|ensembl:ENSP00000322716|uniprotkb:Q6P1Q2|uniprotkb:C9JJ40|uniprotkb:Q9BTI1|uniprotkb:Q9BXK2|uniprotkb:Q6V3W7|uniprotkb:C9JJ60|uniprotkb:B4DL47|uniprotkb:Q5U632 psi-mi:stk3_human(display_long)|uniprotkb:STE20-like kinase MST2(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Krs-1(gene name synonym)|uniprotkb:STK3(gene name)|psi-mi:STK3(display_short)|uniprotkb:MST2(gene name synonym)|uniprotkb:KRS1(gene name synonym) psi-mi:glyr1_human(display_long)|uniprotkb:HIBDL(gene name synonym)|uniprotkb:NP60(gene name synonym)|uniprotkb:3-hydroxyisobutyrate dehydrogenase-like protein(gene name synonym)|uniprotkb:Cytokine-like nuclear factor N-PAC(gene name synonym)|uniprotkb:Glyoxylate reductase 1 homolog(gene name synonym)|uniprotkb:Nuclear protein NP60(gene name synonym)|uniprotkb:Nuclear protein of 60 kDa(gene name synonym)|uniprotkb:GLYR1(gene name)|psi-mi:GLYR1(display_short)|uniprotkb:NDF(gene name synonym)|uniprotkb:Nucleosome-destabilizing factor(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485497|imex:IM-26985-585 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001243241.1|refseq:NP_006272.2|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024205|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|interpro:IPR036674|mint:Q13188|rcsb pdb:3WWS|rcsb pdb:4HKD|rcsb pdb:4L0N|rcsb pdb:4LG4|rcsb pdb:4LGD|rcsb pdb:4OH9|rcsb pdb:5BRM|rcsb pdb:5DH3|rcsb pdb:6AO5|rcsb pdb:6AR2|reactome:R-HSA-2028269|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060215"(primitive hemopoiesis)|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0060800"(regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0106311"|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|ensembl:ENSG00000104375(gene)|ensembl:ENST00000419617(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001841"(neural tube formation)|go:"GO:0003157"(endocardium development)|dip:DIP-36128N ensembl:ENSG00000140632(gene)|ensembl:ENST00000321919(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0042393"(histone binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050661"(NADP binding)|go:"GO:0051287"(NAD binding)|interpro:IPR000313(PWWP)|interpro:IPR006115(6-phosphogluconate dehydrogenase, NAD-binding)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR013328(Dehydrogenase, multihelical)|interpro:IPR029154|interpro:IPR035501|interpro:IPR036291|mint:Q49A26|rcsb pdb:2UYY|rcsb pdb:4GUR|rcsb pdb:4GUS|rcsb pdb:4GUT|rcsb pdb:4GUU|rcsb pdb:4HSU|rcsb pdb:6R1U|rcsb pdb:6R25|refseq:XP_011521019.1|refseq:NP_001295025.1|refseq:NP_115958.2|refseq:NP_001311026.1 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:slrC4Ax6263chBC1DJygdoExuCc9606 rogid:QsJhkB7Klk8D2R03vqPZzbi3f9g9606 rigid:Mda+iwWrR8+UCIMOZvFI/X2uEro false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13188 uniprotkb:Q7Z7K6 intact:EBI-992580|uniprotkb:Q15445|uniprotkb:Q15801|uniprotkb:Q96FM6|uniprotkb:A8K722|ensembl:ENSP00000390500|uniprotkb:B3KYA7 intact:EBI-1210604|uniprotkb:Q3L8N5|uniprotkb:Q8NFH6|uniprotkb:B2RPK2 psi-mi:stk3_human(display_long)|uniprotkb:STE20-like kinase MST2(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Krs-1(gene name synonym)|uniprotkb:STK3(gene name)|psi-mi:STK3(display_short)|uniprotkb:MST2(gene name synonym)|uniprotkb:KRS1(gene name synonym) psi-mi:cenpv_human(display_long)|uniprotkb:CENPV(gene name)|psi-mi:CENPV(display_short)|uniprotkb:Nuclear protein p30(gene name synonym)|uniprotkb:PRR6(gene name synonym)|uniprotkb:Proline-rich protein 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485497|imex:IM-26985-585 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001243241.1|refseq:NP_006272.2|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024205|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|interpro:IPR036674|mint:Q13188|rcsb pdb:3WWS|rcsb pdb:4HKD|rcsb pdb:4L0N|rcsb pdb:4LG4|rcsb pdb:4LGD|rcsb pdb:4OH9|rcsb pdb:5BRM|rcsb pdb:5DH3|rcsb pdb:6AO5|rcsb pdb:6AR2|reactome:R-HSA-2028269|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060215"(primitive hemopoiesis)|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0060800"(regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0106311"|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|ensembl:ENSG00000104375(gene)|ensembl:ENST00000419617(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001841"(neural tube formation)|go:"GO:0003157"(endocardium development)|dip:DIP-36128N refseq:NP_859067.2|interpro:IPR006913(Glutathione-dependent formaldehyde-activating, GFA)|interpro:IPR011057(Mss4-like)|mint:Q7Z7K6|go:"GO:0000776"(kinetochore)|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016846"(carbon-sulfur lyase activity)|go:"GO:0030496"(midbody)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0033044"(regulation of chromosome organization)|go:"GO:0034508"(centromere complex assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0005829"(cytosol) - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:slrC4Ax6263chBC1DJygdoExuCc9606 rogid:q2Dt9PEcUigyqjqFMVm3dxk54B09606 rigid:Mda+iwWrR8+UCIMOZvFI/X2uEro false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13188 uniprotkb:Q9Y3C1 intact:EBI-992580|uniprotkb:Q15445|uniprotkb:Q15801|uniprotkb:Q96FM6|uniprotkb:A8K722|ensembl:ENSP00000390500|uniprotkb:B3KYA7 intact:EBI-5453434|uniprotkb:Q6IAI6|uniprotkb:Q8IXL5|uniprotkb:Q6PIM0|uniprotkb:B4DV13|uniprotkb:D6RGD3|uniprotkb:Q05D05|ensembl:ENSP00000480832 psi-mi:stk3_human(display_long)|uniprotkb:STE20-like kinase MST2(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Krs-1(gene name synonym)|uniprotkb:STK3(gene name)|psi-mi:STK3(display_short)|uniprotkb:MST2(gene name synonym)|uniprotkb:KRS1(gene name synonym) psi-mi:nop16_human(display_long)|uniprotkb:NOP16(gene name)|psi-mi:NOP16(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 3(gene name synonym)|uniprotkb:CGI-117(orf name)|uniprotkb:HSPC111(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485497|imex:IM-26985-585 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001243241.1|refseq:NP_006272.2|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024205|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|interpro:IPR036674|mint:Q13188|rcsb pdb:3WWS|rcsb pdb:4HKD|rcsb pdb:4L0N|rcsb pdb:4LG4|rcsb pdb:4LGD|rcsb pdb:4OH9|rcsb pdb:5BRM|rcsb pdb:5DH3|rcsb pdb:6AO5|rcsb pdb:6AR2|reactome:R-HSA-2028269|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060215"(primitive hemopoiesis)|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0060800"(regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0106311"|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|ensembl:ENSG00000104375(gene)|ensembl:ENST00000419617(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001841"(neural tube formation)|go:"GO:0003157"(endocardium development)|dip:DIP-36128N refseq:NP_057475.2|refseq:NP_001304904.1|refseq:NP_001243468.2|refseq:NP_001278234.1|refseq:NP_001278236.1|refseq:NP_001278237.1|refseq:NP_001243469.2|ensembl:ENSG00000048162(gene)|ensembl:ENST00000614830(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019002|mint:Q9Y3C1 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:slrC4Ax6263chBC1DJygdoExuCc9606 rogid:HdIqgMgye+B+sa3XiPdqvLXbcR89606 rigid:Mda+iwWrR8+UCIMOZvFI/X2uEro false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13188 uniprotkb:Q8WWW0 intact:EBI-992580|uniprotkb:Q15445|uniprotkb:Q15801|uniprotkb:Q96FM6|uniprotkb:A8K722|ensembl:ENSP00000390500|uniprotkb:B3KYA7 intact:EBI-367390|uniprotkb:Q5SY32|uniprotkb:Q8WWV9|uniprotkb:Q8WXF4|uniprotkb:Q9BT99|uniprotkb:A8K1E6|ensembl:ENSP00000462099 psi-mi:stk3_human(display_long)|uniprotkb:STE20-like kinase MST2(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Krs-1(gene name synonym)|uniprotkb:STK3(gene name)|psi-mi:STK3(display_short)|uniprotkb:MST2(gene name synonym)|uniprotkb:KRS1(gene name synonym) psi-mi:rasf5_human(display_long)|uniprotkb:RAPL(gene name synonym)|uniprotkb:RASSF5(gene name)|psi-mi:RASSF5(display_short)|uniprotkb:NORE1(gene name synonym)|uniprotkb:New ras effector 1(gene name synonym)|uniprotkb:Regulator for cell adhesion and polarization enriched in lymphoid tissues(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485497|imex:IM-26985-585 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001243241.1|refseq:NP_006272.2|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024205|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|interpro:IPR036674|mint:Q13188|rcsb pdb:3WWS|rcsb pdb:4HKD|rcsb pdb:4L0N|rcsb pdb:4LG4|rcsb pdb:4LGD|rcsb pdb:4OH9|rcsb pdb:5BRM|rcsb pdb:5DH3|rcsb pdb:6AO5|rcsb pdb:6AR2|reactome:R-HSA-2028269|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060215"(primitive hemopoiesis)|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0060800"(regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0106311"|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|ensembl:ENSG00000104375(gene)|ensembl:ENST00000419617(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001841"(neural tube formation)|go:"GO:0003157"(endocardium development)|dip:DIP-36128N refseq:NP_872604.1|refseq:NP_872605.1|refseq:NP_872606.1|ensembl:ENSG00000266094(gene)|ensembl:ENST00000579436(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0046872"(metal ion binding)|go:"GO:1900180"(regulation of protein localization to nucleus)|interpro:IPR000159(Ras-association)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011524(SARAH)|interpro:IPR029071|interpro:IPR033614|interpro:IPR033623|mint:Q8WWW0|rcsb pdb:4LGD|rcsb pdb:4OH8|dip:DIP-32490N - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:slrC4Ax6263chBC1DJygdoExuCc9606 rogid:EqQpr1Zt1laHo0Y23CpTVMnl28Y9606 rigid:Mda+iwWrR8+UCIMOZvFI/X2uEro false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13188 uniprotkb:Q9H4B6 intact:EBI-992580|uniprotkb:Q15445|uniprotkb:Q15801|uniprotkb:Q96FM6|uniprotkb:A8K722|ensembl:ENSP00000390500|uniprotkb:B3KYA7 intact:EBI-1017775|uniprotkb:Q6IA58|uniprotkb:Q9H949|uniprotkb:Q9HAK9|uniprotkb:A8K4B8|uniprotkb:D3DSB6|ensembl:ENSP00000324729 psi-mi:stk3_human(display_long)|uniprotkb:STE20-like kinase MST2(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Krs-1(gene name synonym)|uniprotkb:STK3(gene name)|psi-mi:STK3(display_short)|uniprotkb:MST2(gene name synonym)|uniprotkb:KRS1(gene name synonym) psi-mi:sav1_human(display_long)|uniprotkb:SAV1(gene name)|psi-mi:SAV1(display_short)|uniprotkb:WW45(gene name synonym)|uniprotkb:45 kDa WW domain protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485497|imex:IM-26985-585 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001243241.1|refseq:NP_006272.2|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024205|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|interpro:IPR036674|mint:Q13188|rcsb pdb:3WWS|rcsb pdb:4HKD|rcsb pdb:4L0N|rcsb pdb:4LG4|rcsb pdb:4LGD|rcsb pdb:4OH9|rcsb pdb:5BRM|rcsb pdb:5DH3|rcsb pdb:6AO5|rcsb pdb:6AR2|reactome:R-HSA-2028269|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060215"(primitive hemopoiesis)|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0060800"(regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0106311"|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|ensembl:ENSG00000104375(gene)|ensembl:ENST00000419617(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001841"(neural tube formation)|go:"GO:0003157"(endocardium development)|dip:DIP-36128N refseq:NP_068590.1|ensembl:ENSG00000151748(gene)|ensembl:ENST00000324679(transcript)|go:"GO:0001942"(hair follicle development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0035329"(hippo signaling)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0046332"(SMAD binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060044"(negative regulation of cardiac muscle cell proliferation)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060487"(lung epithelial cell differentiation)|go:"GO:0060575"(intestinal epithelial cell differentiation)|go:"GO:0070699"(type II activin receptor binding)|go:"GO:2000036"(regulation of stem cell population maintenance)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR011524(SARAH)|interpro:IPR030030|interpro:IPR036020|mint:Q9H4B6|rcsb pdb:6AO5|reactome:R-HSA-2028269|dip:DIP-36127N - - comment:"author score: 48" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:slrC4Ax6263chBC1DJygdoExuCc9606 rogid:djvNX49LV19MDK/wNLfLkX2JMxM9606 rigid:Mda+iwWrR8+UCIMOZvFI/X2uEro false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q13188 uniprotkb:Q9NS23 intact:EBI-992580|uniprotkb:Q15445|uniprotkb:Q15801|uniprotkb:Q96FM6|uniprotkb:A8K722|ensembl:ENSP00000390500|uniprotkb:B3KYA7 intact:EBI-367363|uniprotkb:B7ZLL1|uniprotkb:Q0VGC6|uniprotkb:O14571|uniprotkb:O60539|uniprotkb:O60710|uniprotkb:Q9HB04|uniprotkb:Q9HB18|uniprotkb:Q9NS22|uniprotkb:Q9UND4|uniprotkb:Q9UND5|intact:EBI-2556435|uniprotkb:Q5TZT2|ensembl:ENSP00000349547 psi-mi:stk3_human(display_long)|uniprotkb:STE20-like kinase MST2(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 2(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Krs-1(gene name synonym)|uniprotkb:STK3(gene name)|psi-mi:STK3(display_short)|uniprotkb:MST2(gene name synonym)|uniprotkb:KRS1(gene name synonym) psi-mi:rasf1_human(display_long)|uniprotkb:RASSF1(gene name)|psi-mi:RASSF1(display_short)|uniprotkb:RDA32(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485497|imex:IM-26985-585 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001243241.1|refseq:NP_006272.2|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024205|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|interpro:IPR036674|mint:Q13188|rcsb pdb:3WWS|rcsb pdb:4HKD|rcsb pdb:4L0N|rcsb pdb:4LG4|rcsb pdb:4LGD|rcsb pdb:4OH9|rcsb pdb:5BRM|rcsb pdb:5DH3|rcsb pdb:6AO5|rcsb pdb:6AR2|reactome:R-HSA-2028269|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060215"(primitive hemopoiesis)|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0060800"(regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0106311"|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|ensembl:ENSG00000104375(gene)|ensembl:ENST00000419617(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001841"(neural tube formation)|go:"GO:0003157"(endocardium development)|dip:DIP-36128N refseq:XP_011531617.1|refseq:XP_011531618.1|refseq:NP_001193886.1|refseq:NP_009113.3|refseq:NP_733830.1|refseq:NP_733831.1|refseq:NP_733832.1|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|interpro:IPR000159(Ras-association)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR011524(SARAH)|interpro:IPR029071|interpro:IPR033600|interpro:IPR033614|mint:Q9NS23|rcsb pdb:2KZU|ensembl:ENSG00000068028(gene)|ensembl:ENST00000357043(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005874"(microtubule)|go:"GO:0006974"(cellular response to DNA damage stimulus)|dip:DIP-31270N - - comment:"author score: 55" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:slrC4Ax6263chBC1DJygdoExuCc9606 rogid:kMwpeQ92/ax7NZwtEVal0/XilaI9606 rigid:Mda+iwWrR8+UCIMOZvFI/X2uEro false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NWT6 uniprotkb:P40763 intact:EBI-745632|uniprotkb:Q969Q7|uniprotkb:Q9NPV5|uniprotkb:Q5W147|ensembl:ENSP00000299163|uniprotkb:D3DR69 intact:EBI-518675|uniprotkb:O14916|uniprotkb:Q9BW54|ensembl:ENSP00000264657|ensembl:ENSP00000467985|ensembl:ENSP00000503102|ensembl:ENSP00000503181|ensembl:ENSP00000504184|uniprotkb:A8K7B8|uniprotkb:K7ENL3 psi-mi:hif1n_human(display_long)|uniprotkb:Hypoxia-inducible factor asparagine hydroxylase(gene name synonym)|uniprotkb:Factor inhibiting HIF-1(gene name synonym)|uniprotkb:HIF1AN(gene name)|psi-mi:HIF1AN(display_short)|uniprotkb:FIH1(gene name synonym) psi-mi:stat3_human(display_long)|uniprotkb:Acute-phase response factor(gene name synonym)|uniprotkb:STAT3(gene name)|psi-mi:STAT3(display_short)|uniprotkb:APRF(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25485488|imex:IM-26985-511 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060372.2|ensembl:ENSG00000166135(gene)|ensembl:ENST00000299163(transcript)|go:"GO:0005112"(Notch binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016706"(2-oxoglutarate-dependent dioxygenase activity)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0036138"(peptidyl-histidine hydroxylation)|go:"GO:0036139"(peptidyl-histidine dioxygenase activity)|go:"GO:0036140"(peptidyl-asparagine 3-dioxygenase activity)|go:"GO:0042264"(peptidyl-aspartic acid hydroxylation)|go:"GO:0042265"(peptidyl-asparagine hydroxylation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045663"(positive regulation of myoblast differentiation)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0061428"(negative regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0071532"(ankyrin repeat binding)|go:"GO:0102113"(hypoxia-inducible factor-asparagine oxygenase activity)|go:"GO:2001214"(positive regulation of vasculogenesis)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR014710(RmlC-like jelly roll fold)|interpro:IPR027445|interpro:IPR027452|interpro:IPR041667|mint:Q9NWT6|rcsb pdb:1H2K|rcsb pdb:1H2L|rcsb pdb:1H2M|rcsb pdb:1H2N|rcsb pdb:1IZ3|rcsb pdb:1MZE|rcsb pdb:1MZF|rcsb pdb:1YCI|rcsb pdb:2CGN|rcsb pdb:2CGO|rcsb pdb:2ILM|rcsb pdb:2W0X|rcsb pdb:2WA3|rcsb pdb:2WA4|rcsb pdb:2XUM|rcsb pdb:2Y0I|rcsb pdb:2YC0|rcsb pdb:2YDE|rcsb pdb:3D8C|rcsb pdb:3KCX|rcsb pdb:3KCY|rcsb pdb:3OD4|rcsb pdb:3P3N|rcsb pdb:3P3P|rcsb pdb:4AI8|rcsb pdb:4B7E|rcsb pdb:4B7K|rcsb pdb:4BIO|rcsb pdb:4JAA|rcsb pdb:4NR1|rcsb pdb:4Z1V|rcsb pdb:4Z2W|rcsb pdb:5JWK|rcsb pdb:5JWL|rcsb pdb:5JWP|rcsb pdb:5OP6|rcsb pdb:6H9J|rcsb pdb:6HA6|rcsb pdb:6HC8|rcsb pdb:6HKP|rcsb pdb:6HL5|rcsb pdb:6HL6|rcsb pdb:6RUJ|reactome:R-HSA-1234174|rcsb pdb:5OP8|rcsb pdb:5OPC|dip:DIP-35527N ensembl:ENSG00000168610(gene)|ensembl:ENST00000264657(transcript)|ensembl:ENST00000588969(transcript)|ensembl:ENST00000678044(transcript)|ensembl:ENST00000678906(transcript)|ensembl:ENST00000678960(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001659"(temperature homeostasis)|go:"GO:0001754"(eye photoreceptor cell differentiation)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0004879"(nuclear receptor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0010730"(negative regulation of hydrogen peroxide biosynthetic process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016310"(phosphorylation)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019953"(sexual reproduction)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030522"(intracellular receptor signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006952"(defense response)|go:"GO:0006953"(acute-phase response)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007399"(nervous system development)|go:"GO:0007568"(aging)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0032355"(response to estradiol)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0033210"(leptin-mediated signaling pathway)|go:"GO:0035259"(glucocorticoid receptor binding)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042755"(eating behavior)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0044321"(response to leptin)|go:"GO:0045471"(response to ethanol)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045820"(negative regulation of glycolytic process)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046902"(regulation of mitochondrial membrane permeability)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060019"(radial glial cell differentiation)|go:"GO:0060259"(regulation of feeding behavior)|go:"GO:0060396"(growth hormone receptor signaling pathway)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0072538"(T-helper 17 type immune response)|go:"GO:0072540"(T-helper 17 cell lineage commitment)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097009"(energy homeostasis)|reactome:R-HSA-8875791|reactome:R-HSA-8983432|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9008059|reactome:R-HSA-9020933|reactome:R-HSA-9020956|reactome:R-HSA-9020958|reactome:R-HSA-9616222|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-9707564|reactome:R-HSA-982772|mint:P40763|rcsb pdb:5AX3|rcsb pdb:5U5S|rcsb pdb:6NJS|rcsb pdb:6NUQ|rcsb pdb:6QHD|rcsb pdb:6TLC|reactome:R-HSA-1059683|reactome:R-HSA-111453|reactome:R-HSA-1266695|reactome:R-HSA-1433557|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-198745|reactome:R-HSA-2559582|reactome:R-HSA-2586552|reactome:R-HSA-2892247|reactome:R-HSA-390471|reactome:R-HSA-452723|reactome:R-HSA-6783783|reactome:R-HSA-6785807|reactome:R-HSA-8849474|reactome:R-HSA-8854691|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1900017"(positive regulation of cytokine production involved in inflammatory response)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902728"(positive regulation of growth factor dependent skeletal muscle satellite cell proliferation)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904685"(positive regulation of metalloendopeptidase activity)|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:2000635"(negative regulation of primary miRNA processing)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR035855|interpro:IPR036535|interpro:IPR036860|refseq:NP_003141.2|refseq:NP_644805.1|refseq:NP_998827.1|refseq:XP_011523447.1|refseq:XP_011523448.1|refseq:XP_005257673.2|refseq:XP_005257674.2|refseq:XP_016880461.1|refseq:XP_016880464.1|dip:DIP-33584N - comment:"author score: 13" crc64:6C00632211C8012D figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:lvPtfqlB1+hOcdCAwcopj/Yl+3Y9606 rogid:MEbOYO8fRKMGF0zejkJIzR6jACQ9606 rigid:5LZfrO4lIRqclw2BiNYeY5oFS3c false - tandem tag:n-n - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q08945 uniprotkb:P16104 intact:EBI-353771|uniprotkb:Q5BJG8|ensembl:ENSP00000278412 intact:EBI-494830|uniprotkb:Q4ZGJ7|uniprotkb:Q6IAS5|ensembl:ENSP00000364310|ensembl:ENSP00000434024 psi-mi:ssrp1_human(display_long)|uniprotkb:SSRP1(gene name)|psi-mi:SSRP1(display_short)|uniprotkb:FACT80(gene name synonym)|uniprotkb:Facilitates chromatin transcription complex subunit SSRP1(gene name synonym)|uniprotkb:Facilitates chromatin transcription complex 80 kDa subunit(gene name synonym)|uniprotkb:Chromatin-specific transcription elongation factor 80 kDa subunit(gene name synonym)|uniprotkb:Structure-specific recognition protein 1(gene name synonym)|uniprotkb:Recombination signal sequence recognition protein 1(gene name synonym)|uniprotkb:T160(gene name synonym) psi-mi:h2ax_human(display_long)|uniprotkb:H2AX(gene name)|psi-mi:H2AX(display_short)|uniprotkb:H2AFX(gene name synonym)|uniprotkb:Histone H2A.X(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485434|imex:IM-26985-157 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003137.1|ensembl:ENSG00000149136(gene)|ensembl:ENST00000278412(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035101"(FACT complex)|go:"GO:0042393"(histone binding)|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6804756|reactome:R-HSA-75955|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR000969(Structure-specific recognition protein)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR024954|interpro:IPR035417|interpro:IPR036910|interpro:IPR038167|mint:Q08945|rcsb pdb:4IFS|rcsb pdb:5UMR|rcsb pdb:5UMS|rcsb pdb:5VWE|rcsb pdb:6L1E|rcsb pdb:6L1R|rcsb pdb:6L34|rcsb pdb:6UPK|rcsb pdb:6UPL|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|dip:DIP-169N ensembl:ENSG00000188486(gene)|ensembl:ENST00000375167(transcript)|ensembl:ENST00000530167(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000786"(nucleosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|refseq:NP_002096.1|dip:DIP-33604N|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|go:"GO:0005813"(centrosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090398"(cellular senescence)|go:"GO:0090734"(site of DNA damage)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P16104|rcsb pdb:1YDP|rcsb pdb:2AZM|rcsb pdb:2D31|rcsb pdb:2DYP|rcsb pdb:3SHV|rcsb pdb:3SQD|rcsb pdb:3SZM|rcsb pdb:3U3Z|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K - - comment:"author score: 31" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:WmdGVZadHdcS6Nk9SI41xKm+OrU9606 rogid:VQoEp3F8lEBTOj+PDDUzrJCQNZA9606 rigid:XFc2eklKJXphYu1jlz2CELIICuM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q08945 uniprotkb:P06899 intact:EBI-353771|uniprotkb:Q5BJG8|ensembl:ENSP00000278412 intact:EBI-6150252|uniprotkb:B2R4J4|uniprotkb:O60816|ensembl:ENSP00000342886|ensembl:ENSP00000476136 psi-mi:ssrp1_human(display_long)|uniprotkb:SSRP1(gene name)|psi-mi:SSRP1(display_short)|uniprotkb:FACT80(gene name synonym)|uniprotkb:Facilitates chromatin transcription complex subunit SSRP1(gene name synonym)|uniprotkb:Facilitates chromatin transcription complex 80 kDa subunit(gene name synonym)|uniprotkb:Chromatin-specific transcription elongation factor 80 kDa subunit(gene name synonym)|uniprotkb:Structure-specific recognition protein 1(gene name synonym)|uniprotkb:Recombination signal sequence recognition protein 1(gene name synonym)|uniprotkb:T160(gene name synonym) psi-mi:h2b1j_human(display_long)|uniprotkb:H2BC11(gene name)|psi-mi:H2BC11(display_short)|uniprotkb:H2BFR(gene name synonym)|uniprotkb:HIST1H2BJ(gene name synonym)|uniprotkb:Histone H2B.1(gene name synonym)|uniprotkb:Histone H2B.r(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485434|imex:IM-26985-157 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003137.1|ensembl:ENSG00000149136(gene)|ensembl:ENST00000278412(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035101"(FACT complex)|go:"GO:0042393"(histone binding)|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6804756|reactome:R-HSA-75955|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR000969(Structure-specific recognition protein)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR024954|interpro:IPR035417|interpro:IPR036910|interpro:IPR038167|mint:Q08945|rcsb pdb:4IFS|rcsb pdb:5UMR|rcsb pdb:5UMS|rcsb pdb:5VWE|rcsb pdb:6L1E|rcsb pdb:6L1R|rcsb pdb:6L34|rcsb pdb:6UPK|rcsb pdb:6UPL|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|dip:DIP-169N refseq:NP_066402.2|dip:DIP-421N|ensembl:ENSG00000124635(gene)|ensembl:ENST00000339812(transcript)|ensembl:ENST00000607124(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P06899|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WAA|rcsb pdb:3WTP|rcsb pdb:4CAY|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5FUG|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5VEY|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6JXD|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6YOV|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7K5X|rcsb pdb:3WA9|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:WmdGVZadHdcS6Nk9SI41xKm+OrU9606 rogid:74GQlSjGG1Ez6Uog74VXPLryKBc9606 rigid:XFc2eklKJXphYu1jlz2CELIICuM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q08945 uniprotkb:P49736 intact:EBI-353771|uniprotkb:Q5BJG8|ensembl:ENSP00000278412 intact:EBI-374819|uniprotkb:Q14577|uniprotkb:Q15023|uniprotkb:Q8N2V1|uniprotkb:Q969W7|uniprotkb:Q96AE1|uniprotkb:Q9BRM7|ensembl:ENSP00000265056 psi-mi:ssrp1_human(display_long)|uniprotkb:SSRP1(gene name)|psi-mi:SSRP1(display_short)|uniprotkb:FACT80(gene name synonym)|uniprotkb:Facilitates chromatin transcription complex subunit SSRP1(gene name synonym)|uniprotkb:Facilitates chromatin transcription complex 80 kDa subunit(gene name synonym)|uniprotkb:Chromatin-specific transcription elongation factor 80 kDa subunit(gene name synonym)|uniprotkb:Structure-specific recognition protein 1(gene name synonym)|uniprotkb:Recombination signal sequence recognition protein 1(gene name synonym)|uniprotkb:T160(gene name synonym) psi-mi:mcm2_human(display_long)|uniprotkb:MCM2(gene name)|psi-mi:MCM2(display_short)|uniprotkb:BM28(gene name synonym)|uniprotkb:CDCL1(gene name synonym)|uniprotkb:KIAA0030(gene name synonym)|uniprotkb:Minichromosome maintenance protein 2 homolog(gene name synonym)|uniprotkb:Nuclear protein BM28(gene name synonym)|uniprotkb:CCNL1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485434|imex:IM-26985-157 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003137.1|ensembl:ENSG00000149136(gene)|ensembl:ENST00000278412(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035101"(FACT complex)|go:"GO:0042393"(histone binding)|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6804756|reactome:R-HSA-75955|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR000969(Structure-specific recognition protein)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR024954|interpro:IPR035417|interpro:IPR036910|interpro:IPR038167|mint:Q08945|rcsb pdb:4IFS|rcsb pdb:5UMR|rcsb pdb:5UMS|rcsb pdb:5VWE|rcsb pdb:6L1E|rcsb pdb:6L1R|rcsb pdb:6L34|rcsb pdb:6UPK|rcsb pdb:6UPL|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|dip:DIP-169N ensembl:ENSG00000073111(gene)|ensembl:ENST00000265056(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006915"(apoptotic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0042393"(histone binding)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090102"(cochlea development)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P49736|rcsb pdb:4UUZ|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5JA4|rcsb pdb:6XTX|rcsb pdb:6XTY|rcsb pdb:6YA7|rcsb pdb:7CIZ|rcsb pdb:7CJ0|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|refseq:NP_004517.2|dip:DIP-31732N - - comment:"author score: 30" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:WmdGVZadHdcS6Nk9SI41xKm+OrU9606 rogid:Jt9ODNyJBwtwQ0pb/+X46vtHfE09606 rigid:XFc2eklKJXphYu1jlz2CELIICuM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q08945 uniprotkb:Q9Y5B9 intact:EBI-353771|uniprotkb:Q5BJG8|ensembl:ENSP00000278412 intact:EBI-1046849|uniprotkb:Q6GMT8|uniprotkb:Q6P2F1|uniprotkb:Q6PJM1|uniprotkb:Q9NRX0|ensembl:ENSP00000216297 psi-mi:ssrp1_human(display_long)|uniprotkb:SSRP1(gene name)|psi-mi:SSRP1(display_short)|uniprotkb:FACT80(gene name synonym)|uniprotkb:Facilitates chromatin transcription complex subunit SSRP1(gene name synonym)|uniprotkb:Facilitates chromatin transcription complex 80 kDa subunit(gene name synonym)|uniprotkb:Chromatin-specific transcription elongation factor 80 kDa subunit(gene name synonym)|uniprotkb:Structure-specific recognition protein 1(gene name synonym)|uniprotkb:Recombination signal sequence recognition protein 1(gene name synonym)|uniprotkb:T160(gene name synonym) psi-mi:sp16h_human(display_long)|uniprotkb:Facilitates chromatin transcription complex subunit SPT16(gene name synonym)|uniprotkb:FACT 140 kDa subunit(gene name synonym)|uniprotkb:FACTp140(gene name synonym)|uniprotkb:Chromatin-specific transcription elongation factor 140 kDa subunit(gene name synonym)|uniprotkb:SUPT16H(gene name)|psi-mi:SUPT16H(display_short)|uniprotkb:FACT140(gene name synonym)|uniprotkb:FACTP140(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485434|imex:IM-26985-157 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003137.1|ensembl:ENSG00000149136(gene)|ensembl:ENST00000278412(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0031491"(nucleosome binding)|go:"GO:0035101"(FACT complex)|go:"GO:0042393"(histone binding)|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6804756|reactome:R-HSA-75955|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR000969(Structure-specific recognition protein)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR024954|interpro:IPR035417|interpro:IPR036910|interpro:IPR038167|mint:Q08945|rcsb pdb:4IFS|rcsb pdb:5UMR|rcsb pdb:5UMS|rcsb pdb:5VWE|rcsb pdb:6L1E|rcsb pdb:6L1R|rcsb pdb:6L34|rcsb pdb:6UPK|rcsb pdb:6UPL|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|dip:DIP-169N ensembl:ENSG00000092201(gene)|ensembl:ENST00000216297(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006337"(nucleosome disassembly)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0031491"(nucleosome binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034724"(DNA replication-independent chromatin organization)|go:"GO:0035101"(FACT complex)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013719(Region of unknown function DUF1747, eukaryote)|interpro:IPR013953(FACT complex subunit Spt16p/Cdc68p)|interpro:IPR029148|interpro:IPR029149|interpro:IPR033825|interpro:IPR036005|interpro:IPR040258|mint:Q9Y5B9|rcsb pdb:4Z2M|rcsb pdb:4Z2N|rcsb pdb:5E5B|rcsb pdb:5UMT|rcsb pdb:5UMU|rcsb pdb:5XM2|rcsb pdb:6UPK|rcsb pdb:6UPL|reactome:R-HSA-112382|reactome:R-HSA-167152|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6804756|reactome:R-HSA-75955|refseq:NP_009123.1|dip:DIP-42757N - - comment:"author score: 60" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:WmdGVZadHdcS6Nk9SI41xKm+OrU9606 rogid:jLK5dOF3mEyI0UbZhcNgtdlG+WI9606 rigid:XFc2eklKJXphYu1jlz2CELIICuM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N3U4 uniprotkb:Q8WVM7 intact:EBI-1057252|uniprotkb:O00540|uniprotkb:Q5JTI6|uniprotkb:Q9H1N8|uniprotkb:D3DTF5|intact:EBI-2559208|uniprotkb:B1AMT5|uniprotkb:Q68DE9|ensembl:ENSP00000360186|ensembl:ENSP00000360199|ensembl:ENSP00000360202 intact:EBI-1175097|uniprotkb:O00539|uniprotkb:Q6P275|intact:EBI-11027072|ensembl:ENSP00000372689 psi-mi:stag2_human(display_long)|uniprotkb:STAG2(gene name)|psi-mi:STAG2(display_short)|uniprotkb:SA2(gene name synonym)|uniprotkb:Stromal antigen 2(gene name synonym)|uniprotkb:SCC3 homolog 2(gene name synonym) psi-mi:stag1_human(display_long)|uniprotkb:STAG1(gene name)|psi-mi:STAG1(display_short)|uniprotkb:SA1(gene name synonym)|uniprotkb:Stromal antigen 1(gene name synonym)|uniprotkb:SCC3 homolog 1(gene name synonym)|uniprotkb:SCC3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485452|imex:IM-26985-289 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036214.1|refseq:NP_001036215.1|refseq:NP_001036216.1|refseq:XP_011529555.1|refseq:NP_006594.3|refseq:NP_001269347.1|refseq:XP_005262414.1|refseq:XP_005262415.1|refseq:XP_005262416.1|refseq:XP_005262417.1|refseq:XP_005262418.1|refseq:XP_006724790.1|ensembl:ENSG00000101972(gene)|ensembl:ENST00000371144(transcript)|ensembl:ENST00000371157(transcript)|ensembl:ENST00000371160(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8N3U4|rcsb pdb:4PJU|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0005829"(cytosol)|refseq:XP_016884721.1|refseq:XP_016884722.1|refseq:XP_016884723.1|dip:DIP-35418N refseq:NP_005853.2|ensembl:ENSG00000118007(gene)|ensembl:ENST00000383202(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8WVM7|rcsb pdb:5QSM|rcsb pdb:5QSN|rcsb pdb:5QSO|rcsb pdb:5QSP|rcsb pdb:5QSQ|rcsb pdb:5QSR|rcsb pdb:5QSS|rcsb pdb:5QST|rcsb pdb:5QSU|rcsb pdb:5QSV|rcsb pdb:5QSW|rcsb pdb:5QSX|rcsb pdb:5QSY|rcsb pdb:5QSZ|rcsb pdb:6QB5|rcsb pdb:6R7O|rcsb pdb:6RRC|rcsb pdb:6RRK|rcsb pdb:6WG3|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0016363"(nuclear matrix)|go:"GO:0016604"(nuclear body)|go:"GO:0051301"(cell division)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|dip:DIP-35421N - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:sJ813DVkungq+1f1rgugDN2gsn09606 rogid:rg5wj0+iyr44mtRMgE12tD8X5LY9606 rigid:cx1fXS1ZMn33E959q49rwdmCI6U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N3U4 uniprotkb:Q92889 intact:EBI-1057252|uniprotkb:O00540|uniprotkb:Q5JTI6|uniprotkb:Q9H1N8|uniprotkb:D3DTF5|intact:EBI-2559208|uniprotkb:B1AMT5|uniprotkb:Q68DE9|ensembl:ENSP00000360186|ensembl:ENSP00000360199|ensembl:ENSP00000360202 intact:EBI-2370770|uniprotkb:O00140|uniprotkb:Q8TD83|uniprotkb:A5PKV6|uniprotkb:A8K111|ensembl:ENSP00000310520 psi-mi:stag2_human(display_long)|uniprotkb:STAG2(gene name)|psi-mi:STAG2(display_short)|uniprotkb:SA2(gene name synonym)|uniprotkb:Stromal antigen 2(gene name synonym)|uniprotkb:SCC3 homolog 2(gene name synonym) psi-mi:xpf_human(display_long)|uniprotkb:ERCC4(gene name)|psi-mi:ERCC4(display_short)|uniprotkb:ERCC11(gene name synonym)|uniprotkb:XPF(gene name synonym)|uniprotkb:DNA excision repair protein ERCC-4(gene name synonym)|uniprotkb:DNA repair protein complementing XP-F cells(gene name synonym)|uniprotkb:Xeroderma pigmentosum group F-complementing protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485452|imex:IM-26985-289 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036214.1|refseq:NP_001036215.1|refseq:NP_001036216.1|refseq:XP_011529555.1|refseq:NP_006594.3|refseq:NP_001269347.1|refseq:XP_005262414.1|refseq:XP_005262415.1|refseq:XP_005262416.1|refseq:XP_005262417.1|refseq:XP_005262418.1|refseq:XP_006724790.1|ensembl:ENSG00000101972(gene)|ensembl:ENST00000371144(transcript)|ensembl:ENST00000371157(transcript)|ensembl:ENST00000371160(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8N3U4|rcsb pdb:4PJU|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0005829"(cytosol)|refseq:XP_016884721.1|refseq:XP_016884722.1|refseq:XP_016884723.1|dip:DIP-35418N refseq:NP_005227.1|dip:DIP-42006N|ensembl:ENSG00000175595(gene)|ensembl:ENST00000311895(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000109"(nucleotide-excision repair complex)|go:"GO:0000110"(nucleotide-excision repair factor 1 complex)|go:"GO:0000712"(resolution of meiotic recombination intermediates)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006295"(nucleotide-excision repair, DNA incision, 3'-to lesion)|go:"GO:0006296"(nucleotide-excision repair, DNA incision, 5'-to lesion)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0009411"(response to UV)|go:"GO:0009650"(UV protection)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0032205"(negative regulation of telomere maintenance)|go:"GO:0033683"(nucleotide-excision repair, DNA incision)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042802"(identical protein binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0061819"(telomeric DNA-containing double minutes formation)|go:"GO:0070522"(ERCC4-ERCC1 complex)|go:"GO:1901255"(nucleotide-excision repair involved in interstrand cross-link repair)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1905765"(negative regulation of protection from non-homologous end joining at telomere)|go:"GO:1905768"(negative regulation of double-stranded telomeric DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR006166(DNA repair nuclease, XPF-type/Helicase)|interpro:IPR006167(DNA repair protein)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|mint:Q92889|rcsb pdb:1Z00|rcsb pdb:2A1J|rcsb pdb:2AQ0|rcsb pdb:2KN7|rcsb pdb:2MUT|rcsb pdb:6SXA|rcsb pdb:6SXB|reactome:R-HSA-5685938|reactome:R-HSA-5696395|reactome:R-HSA-5696400|reactome:R-HSA-6782135|reactome:R-HSA-6783310 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:sJ813DVkungq+1f1rgugDN2gsn09606 rogid:A42t082dZNQH72TF3QRa+Msuoms9606 rigid:cx1fXS1ZMn33E959q49rwdmCI6U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N3U4 uniprotkb:P22528 intact:EBI-1057252|uniprotkb:O00540|uniprotkb:Q5JTI6|uniprotkb:Q9H1N8|uniprotkb:D3DTF5|intact:EBI-2559208|uniprotkb:B1AMT5|uniprotkb:Q68DE9|ensembl:ENSP00000360186|ensembl:ENSP00000360199|ensembl:ENSP00000360202 intact:EBI-1058892|ensembl:ENSP00000306461|uniprotkb:B2R5H7|uniprotkb:P22529|uniprotkb:P22530|uniprotkb:Q5T524 psi-mi:stag2_human(display_long)|uniprotkb:STAG2(gene name)|psi-mi:STAG2(display_short)|uniprotkb:SA2(gene name synonym)|uniprotkb:Stromal antigen 2(gene name synonym)|uniprotkb:SCC3 homolog 2(gene name synonym) psi-mi:spr1b_human(display_long)|uniprotkb:SPRR1B(gene name)|psi-mi:SPRR1B(display_short)|uniprotkb:Small proline-rich protein IB(gene name synonym)|uniprotkb:14.9 kDa pancornulin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485452|imex:IM-26985-289 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036214.1|refseq:NP_001036215.1|refseq:NP_001036216.1|refseq:XP_011529555.1|refseq:NP_006594.3|refseq:NP_001269347.1|refseq:XP_005262414.1|refseq:XP_005262415.1|refseq:XP_005262416.1|refseq:XP_005262417.1|refseq:XP_005262418.1|refseq:XP_006724790.1|ensembl:ENSG00000101972(gene)|ensembl:ENST00000371144(transcript)|ensembl:ENST00000371157(transcript)|ensembl:ENST00000371160(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8N3U4|rcsb pdb:4PJU|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0005829"(cytosol)|refseq:XP_016884721.1|refseq:XP_016884722.1|refseq:XP_016884723.1|dip:DIP-35418N ensembl:ENSG00000169469(gene)|ensembl:ENST00000307098(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0031424"(keratinization)|interpro:IPR003302("Cornifin (SPRR)")|mint:P22528|reactome:R-HSA-6809371|refseq:NP_003116.2 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:sJ813DVkungq+1f1rgugDN2gsn09606 rogid:WU0vu+DHdIJm0x40HdcpAdJgdgo9606 rigid:cx1fXS1ZMn33E959q49rwdmCI6U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N3U4 uniprotkb:P49354 intact:EBI-1057252|uniprotkb:O00540|uniprotkb:Q5JTI6|uniprotkb:Q9H1N8|uniprotkb:D3DTF5|intact:EBI-2559208|uniprotkb:B1AMT5|uniprotkb:Q68DE9|ensembl:ENSP00000360186|ensembl:ENSP00000360199|ensembl:ENSP00000360202 intact:EBI-602336|uniprotkb:Q9UDC1|uniprotkb:A6NJW0|uniprotkb:Q53XJ9|ensembl:ENSP00000303423 psi-mi:stag2_human(display_long)|uniprotkb:STAG2(gene name)|psi-mi:STAG2(display_short)|uniprotkb:SA2(gene name synonym)|uniprotkb:Stromal antigen 2(gene name synonym)|uniprotkb:SCC3 homolog 2(gene name synonym) psi-mi:fnta_human(display_long)|uniprotkb:CAAX farnesyltransferase subunit alpha(gene name synonym)|uniprotkb:Ras proteins prenyltransferase subunit alpha(gene name synonym)|uniprotkb:FTase-alpha(gene name synonym)|uniprotkb:Type I protein geranyl-geranyltransferase subunit alpha(gene name synonym)|uniprotkb:FNTA(gene name)|psi-mi:FNTA(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485452|imex:IM-26985-289 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036214.1|refseq:NP_001036215.1|refseq:NP_001036216.1|refseq:XP_011529555.1|refseq:NP_006594.3|refseq:NP_001269347.1|refseq:XP_005262414.1|refseq:XP_005262415.1|refseq:XP_005262416.1|refseq:XP_005262417.1|refseq:XP_005262418.1|refseq:XP_006724790.1|ensembl:ENSG00000101972(gene)|ensembl:ENST00000371144(transcript)|ensembl:ENST00000371157(transcript)|ensembl:ENST00000371160(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8N3U4|rcsb pdb:4PJU|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0005829"(cytosol)|refseq:XP_016884721.1|refseq:XP_016884722.1|refseq:XP_016884723.1|dip:DIP-35418N refseq:NP_002018.1|ensembl:ENSG00000168522(gene)|ensembl:ENST00000302279(transcript)|go:"GO:0004660"(protein farnesyltransferase activity)|go:"GO:0004661"(protein geranylgeranyltransferase activity)|go:"GO:0004662"(CAAX-protein geranylgeranyltransferase activity)|go:"GO:0004663"(Rab geranylgeranyltransferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005953"(CAAX-protein geranylgeranyltransferase complex)|go:"GO:0005965"(protein farnesyltransferase complex)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0018343"(protein farnesylation)|go:"GO:0018344"(protein geranylgeranylation)|go:"GO:0030548"(acetylcholine receptor regulator activity)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0045213"(neurotransmitter receptor metabolic process)|go:"GO:0071340"(skeletal muscle acetylcholine-gated channel clustering)|go:"GO:0090044"(positive regulation of tubulin deacetylation)|go:"GO:0090045"(positive regulation of deacetylase activity)|interpro:IPR002088(Protein prenyltransferase, alpha subunit)|mint:P49354|rcsb pdb:1JCQ|rcsb pdb:1LD7|rcsb pdb:1LD8|rcsb pdb:1MZC|rcsb pdb:1S63|rcsb pdb:1SA4|rcsb pdb:1TN6|rcsb pdb:2F0Y|rcsb pdb:2H6F|rcsb pdb:2H6G|rcsb pdb:2H6H|rcsb pdb:2H6I|rcsb pdb:2IEJ|rcsb pdb:3E37|reactome:R-HSA-111465|reactome:R-HSA-2514859|reactome:R-HSA-9648002 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:sJ813DVkungq+1f1rgugDN2gsn09606 rogid:2VOoFRlMYQR1v9oiOKl1sktjaa09606 rigid:cx1fXS1ZMn33E959q49rwdmCI6U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N3U4 uniprotkb:Q9Y241 intact:EBI-1057252|uniprotkb:O00540|uniprotkb:Q5JTI6|uniprotkb:Q9H1N8|uniprotkb:D3DTF5|intact:EBI-2559208|uniprotkb:B1AMT5|uniprotkb:Q68DE9|ensembl:ENSP00000360186|ensembl:ENSP00000360199|ensembl:ENSP00000360202 intact:EBI-1051940|uniprotkb:Q9UFZ2|ensembl:ENSP00000319393|ensembl:ENSP00000402160 psi-mi:stag2_human(display_long)|uniprotkb:STAG2(gene name)|psi-mi:STAG2(display_short)|uniprotkb:SA2(gene name synonym)|uniprotkb:Stromal antigen 2(gene name synonym)|uniprotkb:SCC3 homolog 2(gene name synonym) psi-mi:hig1a_human(display_long)|uniprotkb:Hypoxia-inducible gene 1 protein(gene name synonym)|uniprotkb:HIGD1A(gene name)|psi-mi:HIGD1A(display_short)|uniprotkb:HIG1(gene name synonym)|uniprotkb:RCF1 homolog A(gene name synonym)|uniprotkb:HSPC010(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485452|imex:IM-26985-289 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036214.1|refseq:NP_001036215.1|refseq:NP_001036216.1|refseq:XP_011529555.1|refseq:NP_006594.3|refseq:NP_001269347.1|refseq:XP_005262414.1|refseq:XP_005262415.1|refseq:XP_005262416.1|refseq:XP_005262417.1|refseq:XP_005262418.1|refseq:XP_006724790.1|ensembl:ENSG00000101972(gene)|ensembl:ENST00000371144(transcript)|ensembl:ENST00000371157(transcript)|ensembl:ENST00000371160(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8N3U4|rcsb pdb:4PJU|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0005829"(cytosol)|refseq:XP_016884721.1|refseq:XP_016884722.1|refseq:XP_016884723.1|dip:DIP-35418N refseq:NP_001093138.1|refseq:NP_001093139.1|refseq:NP_054775.2|ensembl:ENSG00000181061(gene)|ensembl:ENST00000321331(transcript)|ensembl:ENST00000418900(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070469"(respirasome)|go:"GO:0097250"(mitochondrial respirasome assembly)|interpro:IPR007667(Hypoxia induced protein conserved region)|mint:Q9Y241|rcsb pdb:2LOM|reactome:R-HSA-1234158 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:sJ813DVkungq+1f1rgugDN2gsn09606 rogid:xFklQUZRMs1m+6gbSJu2tKVz0Dk9606 rigid:cx1fXS1ZMn33E959q49rwdmCI6U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N3U4 uniprotkb:P81605 intact:EBI-1057252|uniprotkb:O00540|uniprotkb:Q5JTI6|uniprotkb:Q9H1N8|uniprotkb:D3DTF5|intact:EBI-2559208|uniprotkb:B1AMT5|uniprotkb:Q68DE9|ensembl:ENSP00000360186|ensembl:ENSP00000360199|ensembl:ENSP00000360202 intact:EBI-395625|uniprotkb:P58461|uniprotkb:A5JHP2|uniprotkb:A5JHP3|uniprotkb:Q53YJ2|ensembl:ENSP00000293371 psi-mi:stag2_human(display_long)|uniprotkb:STAG2(gene name)|psi-mi:STAG2(display_short)|uniprotkb:SA2(gene name synonym)|uniprotkb:Stromal antigen 2(gene name synonym)|uniprotkb:SCC3 homolog 2(gene name synonym) psi-mi:dcd_human(display_long)|uniprotkb:AIDD(gene name synonym)|uniprotkb:DSEP(gene name synonym)|uniprotkb:Preproteolysin(gene name synonym)|uniprotkb:DCD(gene name)|psi-mi:DCD(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485452|imex:IM-26985-289 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036214.1|refseq:NP_001036215.1|refseq:NP_001036216.1|refseq:XP_011529555.1|refseq:NP_006594.3|refseq:NP_001269347.1|refseq:XP_005262414.1|refseq:XP_005262415.1|refseq:XP_005262416.1|refseq:XP_005262417.1|refseq:XP_005262418.1|refseq:XP_006724790.1|ensembl:ENSG00000101972(gene)|ensembl:ENST00000371144(transcript)|ensembl:ENST00000371157(transcript)|ensembl:ENST00000371160(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8N3U4|rcsb pdb:4PJU|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0005829"(cytosol)|refseq:XP_016884721.1|refseq:XP_016884722.1|refseq:XP_016884723.1|dip:DIP-35418N refseq:NP_444513.1|refseq:NP_001287783.1|ensembl:ENSG00000161634(gene)|ensembl:ENST00000293371(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008233"(peptidase activity)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR028130|interpro:IPR043557|mint:P81605|rcsb pdb:2KSG|rcsb pdb:2NDK|rcsb pdb:2YMK|rcsb pdb:6SHK|reactome:R-HSA-6803157 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:sJ813DVkungq+1f1rgugDN2gsn09606 rogid:M8PkKVWx98nhtd79ods05mqw8Ls9606 rigid:cx1fXS1ZMn33E959q49rwdmCI6U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N3U4 uniprotkb:P68363 intact:EBI-1057252|uniprotkb:O00540|uniprotkb:Q5JTI6|uniprotkb:Q9H1N8|uniprotkb:D3DTF5|intact:EBI-2559208|uniprotkb:B1AMT5|uniprotkb:Q68DE9|ensembl:ENSP00000360186|ensembl:ENSP00000360199|ensembl:ENSP00000360202 intact:EBI-487083|intact:EBI-1384226|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:Q27I68|ensembl:ENSP00000336799|uniprotkb:Q8WU19 psi-mi:stag2_human(display_long)|uniprotkb:STAG2(gene name)|psi-mi:STAG2(display_short)|uniprotkb:SA2(gene name synonym)|uniprotkb:Stromal antigen 2(gene name synonym)|uniprotkb:SCC3 homolog 2(gene name synonym) psi-mi:tba1b_human(display_long)|uniprotkb:TUBA1B(gene name)|psi-mi:TUBA1B(display_short)|uniprotkb:Tubulin alpha-ubiquitous chain(gene name synonym)|uniprotkb:Alpha-tubulin ubiquitous(gene name synonym)|uniprotkb:Tubulin K-alpha-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485452|imex:IM-26985-289 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036214.1|refseq:NP_001036215.1|refseq:NP_001036216.1|refseq:XP_011529555.1|refseq:NP_006594.3|refseq:NP_001269347.1|refseq:XP_005262414.1|refseq:XP_005262415.1|refseq:XP_005262416.1|refseq:XP_005262417.1|refseq:XP_005262418.1|refseq:XP_006724790.1|ensembl:ENSG00000101972(gene)|ensembl:ENST00000371144(transcript)|ensembl:ENST00000371157(transcript)|ensembl:ENST00000371160(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8N3U4|rcsb pdb:4PJU|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0005829"(cytosol)|refseq:XP_016884721.1|refseq:XP_016884722.1|refseq:XP_016884723.1|dip:DIP-35418N refseq:NP_006073.2|ensembl:ENSG00000123416(gene)|ensembl:ENST00000336023(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-983189|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|go:"GO:0045121"(membrane raft)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68363|rcsb pdb:2E4H|rcsb pdb:5IJ0|rcsb pdb:5IJ9|rcsb pdb:5N5N|rcsb pdb:6E7B|rcsb pdb:6E7C|rcsb pdb:6I2I|go:"GO:0051301"(cell division)|rcsb pdb:6J4V|rcsb pdb:6J8O|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|rcsb pdb:6S8L|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9013407|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-2132295|reactome:R-HSA-9668328 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:sJ813DVkungq+1f1rgugDN2gsn09606 rogid:D4YpuLCXl/S+53qV7P7sF81aARY9606 rigid:cx1fXS1ZMn33E959q49rwdmCI6U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N3U4 uniprotkb:Q9UQE7 intact:EBI-1057252|uniprotkb:O00540|uniprotkb:Q5JTI6|uniprotkb:Q9H1N8|uniprotkb:D3DTF5|intact:EBI-2559208|uniprotkb:B1AMT5|uniprotkb:Q68DE9|ensembl:ENSP00000360186|ensembl:ENSP00000360199|ensembl:ENSP00000360202 intact:EBI-80718|ensembl:ENSP00000354720|uniprotkb:O60464|uniprotkb:Q5T482|uniprotkb:A8K156 psi-mi:stag2_human(display_long)|uniprotkb:STAG2(gene name)|psi-mi:STAG2(display_short)|uniprotkb:SA2(gene name synonym)|uniprotkb:Stromal antigen 2(gene name synonym)|uniprotkb:SCC3 homolog 2(gene name synonym) psi-mi:smc3_human(display_long)|uniprotkb:SMC3(gene name)|psi-mi:SMC3(display_short)|uniprotkb:BAM(gene name synonym)|uniprotkb:SMC3L1(gene name synonym)|uniprotkb:Chondroitin sulfate proteoglycan 6(gene name synonym)|uniprotkb:Chromosome-associated polypeptide(gene name synonym)|uniprotkb:Basement membrane-associated chondroitin proteoglycan(gene name synonym)|uniprotkb:BMH(gene name synonym)|uniprotkb:CSPG6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485452|imex:IM-26985-289 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036214.1|refseq:NP_001036215.1|refseq:NP_001036216.1|refseq:XP_011529555.1|refseq:NP_006594.3|refseq:NP_001269347.1|refseq:XP_005262414.1|refseq:XP_005262415.1|refseq:XP_005262416.1|refseq:XP_005262417.1|refseq:XP_005262418.1|refseq:XP_006724790.1|ensembl:ENSG00000101972(gene)|ensembl:ENST00000371144(transcript)|ensembl:ENST00000371157(transcript)|ensembl:ENST00000371160(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8N3U4|rcsb pdb:4PJU|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0005829"(cytosol)|refseq:XP_016884721.1|refseq:XP_016884722.1|refseq:XP_016884723.1|dip:DIP-35418N go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR036277|interpro:IPR041741|mint:Q9UQE7|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0070840"(dynein complex binding)|ensembl:ENSG00000108055(gene)|ensembl:ENST00000361804(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000800"(lateral element)|go:"GO:0003682"(chromatin binding)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|refseq:NP_005436.1|dip:DIP-29200N - - comment:"author score: 54" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:sJ813DVkungq+1f1rgugDN2gsn09606 rogid:pUxr+sTtttRzGlqCRz/25woNtrg9606 rigid:cx1fXS1ZMn33E959q49rwdmCI6U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N3U4 uniprotkb:Q14683 intact:EBI-1057252|uniprotkb:O00540|uniprotkb:Q5JTI6|uniprotkb:Q9H1N8|uniprotkb:D3DTF5|intact:EBI-2559208|uniprotkb:B1AMT5|uniprotkb:Q68DE9|ensembl:ENSP00000360186|ensembl:ENSP00000360199|ensembl:ENSP00000360202 intact:EBI-80690|ensembl:ENSP00000323421|uniprotkb:O14995|uniprotkb:Q16351|uniprotkb:Q2M228 psi-mi:stag2_human(display_long)|uniprotkb:STAG2(gene name)|psi-mi:STAG2(display_short)|uniprotkb:SA2(gene name synonym)|uniprotkb:Stromal antigen 2(gene name synonym)|uniprotkb:SCC3 homolog 2(gene name synonym) psi-mi:smc1a_human(display_long)|uniprotkb:SMC1A(gene name)|psi-mi:SMC1A(display_short)|uniprotkb:DXS423E(gene name synonym)|uniprotkb:KIAA0178(gene name synonym)|uniprotkb:SB1.8(gene name synonym)|uniprotkb:SMC1(gene name synonym)|uniprotkb:SMC1L1(gene name synonym)|uniprotkb:Sb1.8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485452|imex:IM-26985-289 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036214.1|refseq:NP_001036215.1|refseq:NP_001036216.1|refseq:XP_011529555.1|refseq:NP_006594.3|refseq:NP_001269347.1|refseq:XP_005262414.1|refseq:XP_005262415.1|refseq:XP_005262416.1|refseq:XP_005262417.1|refseq:XP_005262418.1|refseq:XP_006724790.1|ensembl:ENSG00000101972(gene)|ensembl:ENST00000371144(transcript)|ensembl:ENST00000371157(transcript)|ensembl:ENST00000371160(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8N3U4|rcsb pdb:4PJU|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0005829"(cytosol)|refseq:XP_016884721.1|refseq:XP_016884722.1|refseq:XP_016884723.1|dip:DIP-35418N ensembl:ENSG00000072501(gene)|ensembl:ENST00000322213(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000776"(kinetochore)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0009314"(response to radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030893"(meiotic cohesin complex)|go:"GO:0036033"(mediator complex binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0072423"(response to DNA damage checkpoint signaling)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR003395(RecF/RecN/SMC protein, N-terminal)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR024704|interpro:IPR027417|interpro:IPR028468|interpro:IPR029683|interpro:IPR036277|mint:Q14683|rcsb pdb:6WG3|rcsb pdb:6WG4|rcsb pdb:6WG6|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|reactome:R-HSA-2468052|refseq:NP_006297.2|dip:DIP-30911N - - comment:"author score: 59" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:sJ813DVkungq+1f1rgugDN2gsn09606 rogid:0UhfA7txIetlcGvSes6d+Bv1ZdY9606 rigid:cx1fXS1ZMn33E959q49rwdmCI6U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N3U4 uniprotkb:O60216 intact:EBI-1057252|uniprotkb:O00540|uniprotkb:Q5JTI6|uniprotkb:Q9H1N8|uniprotkb:D3DTF5|intact:EBI-2559208|uniprotkb:B1AMT5|uniprotkb:Q68DE9|ensembl:ENSP00000360186|ensembl:ENSP00000360199|ensembl:ENSP00000360202 intact:EBI-80739|ensembl:ENSP00000297338|uniprotkb:Q15001|uniprotkb:Q99568|uniprotkb:A8K0E0 psi-mi:stag2_human(display_long)|uniprotkb:STAG2(gene name)|psi-mi:STAG2(display_short)|uniprotkb:SA2(gene name synonym)|uniprotkb:Stromal antigen 2(gene name synonym)|uniprotkb:SCC3 homolog 2(gene name synonym) psi-mi:rad21_human(display_long)|uniprotkb:RAD21(gene name)|psi-mi:RAD21(display_short)|uniprotkb:HR21(gene name synonym)|uniprotkb:KIAA0078(gene name synonym)|uniprotkb:Nuclear matrix protein 1(gene name synonym)|uniprotkb:SCC1 homolog(gene name synonym)|uniprotkb:NXP1(gene name synonym)|uniprotkb:SCC1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485452|imex:IM-26985-289 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001036214.1|refseq:NP_001036215.1|refseq:NP_001036216.1|refseq:XP_011529555.1|refseq:NP_006594.3|refseq:NP_001269347.1|refseq:XP_005262414.1|refseq:XP_005262415.1|refseq:XP_005262416.1|refseq:XP_005262417.1|refseq:XP_005262418.1|refseq:XP_006724790.1|ensembl:ENSG00000101972(gene)|ensembl:ENST00000371144(transcript)|ensembl:ENST00000371157(transcript)|ensembl:ENST00000371160(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0008278"(cohesin complex)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR013721(STAG)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR020839|interpro:IPR039662|mint:Q8N3U4|rcsb pdb:4PJU|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|reactome:R-HSA-1221632|reactome:R-HSA-2467813|reactome:R-HSA-2468052|reactome:R-HSA-2470946|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|go:"GO:0005829"(cytosol)|refseq:XP_016884721.1|refseq:XP_016884722.1|refseq:XP_016884723.1|dip:DIP-35418N ensembl:ENSG00000164754(gene)|ensembl:ENST00000297338(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000795"(synaptonemal complex)|go:"GO:0000922"(spindle pole)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0007064"(mitotic sister chromatid cohesion)|go:"GO:0007130"(synaptonemal complex assembly)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008278"(cohesin complex)|go:"GO:0010972"(negative regulation of G2/M transition of mitotic cell cycle)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034990"(nuclear mitotic cohesin complex)|go:"GO:0034991"(nuclear meiotic cohesin complex)|go:"GO:0045841"(negative regulation of mitotic metaphase/anaphase transition)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0051301"(cell division)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|interpro:IPR006909(Rad21/Rec8 like protein, C-terminal)|interpro:IPR006910(Rad21/Rec8 like protein, N-terminal)|interpro:IPR023093|interpro:IPR036390|interpro:IPR039781|mint:O60216|rcsb pdb:4PJU|rcsb pdb:6WGE|reactome:R-HSA-1221632|reactome:R-HSA-2467813|rcsb pdb:4PJW|rcsb pdb:4PK7|rcsb pdb:6QNX|rcsb pdb:6RRC|reactome:R-HSA-2468052|rcsb pdb:6RRK|reactome:R-HSA-2470946|rcsb pdb:6WG3|reactome:R-HSA-2500257|reactome:R-HSA-3108214|reactome:R-HSA-9018519|refseq:NP_006256.1|dip:DIP-29201N - - comment:"author score: 91" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:sJ813DVkungq+1f1rgugDN2gsn09606 rogid:9H+Fipb91zQo7ie3YHCL7Ardveo9606 rigid:cx1fXS1ZMn33E959q49rwdmCI6U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UII4 uniprotkb:Q4FZB7 intact:EBI-2339540|uniprotkb:B2RTQ1|uniprotkb:Q69G20|intact:EBI-28975860|ensembl:ENSP00000264350 intact:EBI-1047962|uniprotkb:Q3SX56|uniprotkb:Q4V775|uniprotkb:Q6P150|uniprotkb:Q96E44|uniprotkb:Q9BUL0|uniprotkb:Q9H022|uniprotkb:Q9H2K3|uniprotkb:Q9NXV3|uniprotkb:Q9Y393|uniprotkb:B7WNX7|ensembl:ENSP00000305899|ensembl:ENSP00000484858|uniprotkb:A0A0A0MT19 psi-mi:herc5_human(display_long)|uniprotkb:HERC5(gene name)|psi-mi:HERC5(display_short)|uniprotkb:CEB1(gene name synonym)|uniprotkb:CEBP1(gene name synonym)|uniprotkb:HECT domain and RCC1-like domain-containing protein 5(gene name synonym)|uniprotkb:Cyclin-E-binding protein 1(gene name synonym) psi-mi:kmt5b_human(display_long)|uniprotkb:[histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:[histone H4]-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:CGI-85(orf name)|uniprotkb:KMT5B(gene name)|psi-mi:KMT5B(display_short)|uniprotkb:Lysine N-methyltransferase 5B(gene name synonym)|uniprotkb:Lysine-specific methyltransferase 5B(gene name synonym)|uniprotkb:SUV420H1(gene name synonym)|uniprotkb:Suppressor of variegation 4-20 homolog 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25485626|imex:IM-26985-587 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000264350|refseq:NP_057407.2|dip:DIP-44200N|ensembl:ENSG00000138646(gene)|ensembl:ENST00000264350(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0032020"(ISG15-protein conjugation)|go:"GO:0042296"(ISG15 transferase activity)|go:"GO:0045087"(innate immune response)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050688"(regulation of defense response to virus)|go:"GO:0051607"(defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR000569(HECT)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|interpro:IPR035983|mint:Q9UII4|reactome:R-HSA-1169408|reactome:R-HSA-168928|reactome:R-HSA-936440|reactome:R-HSA-983168 refseq:NP_057112.3|refseq:NP_060105.3|refseq:XP_011543393.1|refseq:XP_011543396.1|refseq:NP_001287838.1|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001214(SET)|interpro:IPR025790|interpro:IPR039977|interpro:IPR041938|interpro:IPR044424|mint:Q4FZB7|rcsb pdb:3S8P|rcsb pdb:5CPR|rcsb pdb:5WBV|reactome:R-HSA-3214841|ensembl:ENSG00000110066(gene)|ensembl:ENST00000304363(transcript)|ensembl:ENST00000615954(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0007517"(muscle organ development)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0034772"(histone H4-K20 dimethylation)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0046872"(metal ion binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|refseq:XP_005274092.2|dip:DIP-48656N|refseq:XP_011543395.1 - comment:"author score: 19" - figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:IGuce5qcdMB8PC5u6b6A57FODKY9606 rogid:PtHlCj2DZzd3IA0joU5M307MqM49606 rigid:JcpWZv7FI5LsP5tD90WMGX/4Or8 false - tandem tag:?-? - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43463 uniprotkb:Q969R5 intact:EBI-349968|uniprotkb:Q53G60|uniprotkb:Q6FHK6|ensembl:ENSP00000365877|uniprotkb:B2R6E8|uniprotkb:B4DST0 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 psi-mi:suv91_human(display_long)|uniprotkb:SUV39H1(gene name)|psi-mi:SUV39H1(display_short)|uniprotkb:SUV39H(gene name synonym)|uniprotkb:KMT1A(gene name synonym)|uniprotkb:Suppressor of variegation 3-9 homolog 1(gene name synonym)|uniprotkb:Position-effect variegation 3-9 homolog(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1A(gene name synonym) psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485605|imex:IM-26985-367 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003164.1|ensembl:ENSG00000101945(gene)|ensembl:ENST00000376687(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0006325"(chromatin organization)|go:"GO:0006364"(rRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0036124"(histone H3-K9 trimethylation)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|mint:O43463|rcsb pdb:3MTS|reactome:R-HSA-3214841|reactome:R-HSA-427359|refseq:NP_001269095.1|dip:DIP-32589N refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dbenLwo5hxhGzFD4sLNOVUveElM9606 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rigid:lYEs4EyrvKHIdpX8AqNnItFIrMY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43463 uniprotkb:Q9BYN8 intact:EBI-349968|uniprotkb:Q53G60|uniprotkb:Q6FHK6|ensembl:ENSP00000365877|uniprotkb:B2R6E8|uniprotkb:B4DST0 intact:EBI-721378|uniprotkb:Q96Q58|ensembl:ENSP00000369682 psi-mi:suv91_human(display_long)|uniprotkb:SUV39H1(gene name)|psi-mi:SUV39H1(display_short)|uniprotkb:SUV39H(gene name synonym)|uniprotkb:KMT1A(gene name synonym)|uniprotkb:Suppressor of variegation 3-9 homolog 1(gene name synonym)|uniprotkb:Position-effect variegation 3-9 homolog(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1A(gene name synonym) psi-mi:rt26_human(display_long)|uniprotkb:28S ribosomal protein S13, mitochondrial(gene name synonym)|uniprotkb:MRPS26(gene name)|psi-mi:MRPS26(display_short)|uniprotkb:RPMS13(gene name synonym)|uniprotkb:C20orf193(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein mS26(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485605|imex:IM-26985-367 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003164.1|ensembl:ENSG00000101945(gene)|ensembl:ENST00000376687(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0006325"(chromatin organization)|go:"GO:0006364"(rRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0036124"(histone H3-K9 trimethylation)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|mint:O43463|rcsb pdb:3MTS|reactome:R-HSA-3214841|reactome:R-HSA-427359|refseq:NP_001269095.1|dip:DIP-32589N refseq:NP_110438.1|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000125901(gene)|ensembl:ENST00000380325(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|interpro:IPR026140|mint:Q9BYN8 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dbenLwo5hxhGzFD4sLNOVUveElM9606 rogid:ZygMazfhjHbx+aFhRkeG87c4L6E9606 rigid:lYEs4EyrvKHIdpX8AqNnItFIrMY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43463 uniprotkb:Q13185 intact:EBI-349968|uniprotkb:Q53G60|uniprotkb:Q6FHK6|ensembl:ENSP00000365877|uniprotkb:B2R6E8|uniprotkb:B4DST0 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 psi-mi:suv91_human(display_long)|uniprotkb:SUV39H1(gene name)|psi-mi:SUV39H1(display_short)|uniprotkb:SUV39H(gene name synonym)|uniprotkb:KMT1A(gene name synonym)|uniprotkb:Suppressor of variegation 3-9 homolog 1(gene name synonym)|uniprotkb:Position-effect variegation 3-9 homolog(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1A(gene name synonym) psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485605|imex:IM-26985-367 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003164.1|ensembl:ENSG00000101945(gene)|ensembl:ENST00000376687(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0006325"(chromatin organization)|go:"GO:0006364"(rRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0036124"(histone H3-K9 trimethylation)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|mint:O43463|rcsb pdb:3MTS|reactome:R-HSA-3214841|reactome:R-HSA-427359|refseq:NP_001269095.1|dip:DIP-32589N go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dbenLwo5hxhGzFD4sLNOVUveElM9606 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rigid:lYEs4EyrvKHIdpX8AqNnItFIrMY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43463 uniprotkb:P45973 intact:EBI-349968|uniprotkb:Q53G60|uniprotkb:Q6FHK6|ensembl:ENSP00000365877|uniprotkb:B2R6E8|uniprotkb:B4DST0 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 psi-mi:suv91_human(display_long)|uniprotkb:SUV39H1(gene name)|psi-mi:SUV39H1(display_short)|uniprotkb:SUV39H(gene name synonym)|uniprotkb:KMT1A(gene name synonym)|uniprotkb:Suppressor of variegation 3-9 homolog 1(gene name synonym)|uniprotkb:Position-effect variegation 3-9 homolog(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1A(gene name synonym) psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485605|imex:IM-26985-367 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003164.1|ensembl:ENSG00000101945(gene)|ensembl:ENST00000376687(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0006325"(chromatin organization)|go:"GO:0006364"(rRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0036124"(histone H3-K9 trimethylation)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|mint:O43463|rcsb pdb:3MTS|reactome:R-HSA-3214841|reactome:R-HSA-427359|refseq:NP_001269095.1|dip:DIP-32589N go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dbenLwo5hxhGzFD4sLNOVUveElM9606 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rigid:lYEs4EyrvKHIdpX8AqNnItFIrMY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O43463 uniprotkb:Q8N136 intact:EBI-349968|uniprotkb:Q53G60|uniprotkb:Q6FHK6|ensembl:ENSP00000365877|uniprotkb:B2R6E8|uniprotkb:B4DST0 intact:EBI-6658298|ensembl:ENSP00000311899|uniprotkb:Q8N776|uniprotkb:Q6ZRY1 psi-mi:suv91_human(display_long)|uniprotkb:SUV39H1(gene name)|psi-mi:SUV39H1(display_short)|uniprotkb:SUV39H(gene name synonym)|uniprotkb:KMT1A(gene name synonym)|uniprotkb:Suppressor of variegation 3-9 homolog 1(gene name synonym)|uniprotkb:Position-effect variegation 3-9 homolog(gene name synonym)|uniprotkb:Histone H3-K9 methyltransferase 1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 1A(gene name synonym) psi-mi:daw1_human(display_long)|uniprotkb:DAW1(gene name)|psi-mi:DAW1(display_short)|uniprotkb:Outer row dynein assembly protein 16 homolog(gene name synonym)|uniprotkb:WD repeat-containing protein 69(gene name synonym)|uniprotkb:WDR69(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485605|imex:IM-26985-367 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003164.1|ensembl:ENSG00000101945(gene)|ensembl:ENST00000376687(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000183"(rDNA heterochromatin assembly)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005652"(nuclear lamina)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0006325"(chromatin organization)|go:"GO:0006364"(rRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0030154"(cell differentiation)|go:"GO:0033553"(rDNA heterochromatin)|go:"GO:0034968"(histone lysine methylation)|go:"GO:0036123"(histone H3-K9 dimethylation)|go:"GO:0036124"(histone H3-K9 trimethylation)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046974"("histone methyltransferase activity (H3-K9 specific)")|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048511"(rhythmic process)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR000953(Chromo domain)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR007728(Pre-SET zinc-binding region)|interpro:IPR011381(Histone H3-K9 methyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR023779|interpro:IPR023780|mint:O43463|rcsb pdb:3MTS|reactome:R-HSA-3214841|reactome:R-HSA-427359|refseq:NP_001269095.1|dip:DIP-32589N refseq:NP_001316933.1|ensembl:ENSG00000123977(gene)|ensembl:ENST00000309931(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005929"(cilium)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007507"(heart development)|go:"GO:0036158"(outer dynein arm assembly)|go:"GO:0051649"(establishment of localization in cell)|go:"GO:0090660"(cerebrospinal fluid circulation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q8N136|rcsb pdb:5NNZ|refseq:NP_849143.1 - - comment:"author score: 31" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:dbenLwo5hxhGzFD4sLNOVUveElM9606 rogid:EBknC+lRMjWacMXDNr83pNVo/Jk9606 rigid:lYEs4EyrvKHIdpX8AqNnItFIrMY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00267 uniprotkb:P68363 intact:EBI-710464|ensembl:ENSP00000404029|ensembl:ENSP00000469090|ensembl:ENSP00000470252|uniprotkb:O43279|uniprotkb:Q59G52|uniprotkb:Q99639 intact:EBI-487083|intact:EBI-1384226|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:Q27I68|ensembl:ENSP00000336799|uniprotkb:Q8WU19 psi-mi:spt5h_human(display_long)|uniprotkb:DRB sensitivity-inducing factor large subunit(gene name synonym)|uniprotkb:DRB sensitivity-inducing factor 160 kDa subunit(gene name synonym)|uniprotkb:Tat-cotransactivator 1 protein(gene name synonym)|uniprotkb:SUPT5H(gene name)|psi-mi:SUPT5H(display_short)|uniprotkb:SPT5(gene name synonym)|uniprotkb:SPT5H(gene name synonym) psi-mi:tba1b_human(display_long)|uniprotkb:TUBA1B(gene name)|psi-mi:TUBA1B(display_short)|uniprotkb:Tubulin alpha-ubiquitous chain(gene name synonym)|uniprotkb:Alpha-tubulin ubiquitous(gene name synonym)|uniprotkb:Tubulin K-alpha-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485578|imex:IM-26985-513 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124296.1|refseq:NP_001124297.1|refseq:NP_003160.2|refseq:NP_001104490.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019899"(enzyme binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032785"(negative regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|ensembl:ENSG00000196235(gene)|ensembl:ENST00000432763(transcript)|ensembl:ENST00000598725(transcript)|ensembl:ENST00000599117(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|interpro:IPR041980|mint:O00267|rcsb pdb:2DO3|rcsb pdb:2E6Z|rcsb pdb:2E70|rcsb pdb:3H7H|rcsb pdb:4L1U|rcsb pdb:5OHO|rcsb pdb:5OHQ|rcsb pdb:5OIK|rcsb pdb:5U98|rcsb pdb:6EQY|rcsb pdb:6ER0|rcsb pdb:6GMH|rcsb pdb:6GML|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-75955|reactome:R-HSA-77075|refseq:NP_001306920.1|refseq:NP_001306919.1|dip:DIP-29014N refseq:NP_006073.2|ensembl:ENSG00000123416(gene)|ensembl:ENST00000336023(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-983189|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|go:"GO:0045121"(membrane raft)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68363|rcsb pdb:2E4H|rcsb pdb:5IJ0|rcsb pdb:5IJ9|rcsb pdb:5N5N|rcsb pdb:6E7B|rcsb pdb:6E7C|rcsb pdb:6I2I|go:"GO:0051301"(cell division)|rcsb pdb:6J4V|rcsb pdb:6J8O|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|rcsb pdb:6S8L|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9013407|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-2132295|reactome:R-HSA-9668328 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8VodOhZyrmNy3xxDTTsB8KugN849606 rogid:D4YpuLCXl/S+53qV7P7sF81aARY9606 rigid:yO+hmt/a82GPodA5lPe7rPcp62E false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00267 uniprotkb:O14744 intact:EBI-710464|ensembl:ENSP00000404029|ensembl:ENSP00000469090|ensembl:ENSP00000470252|uniprotkb:O43279|uniprotkb:Q59G52|uniprotkb:Q99639 intact:EBI-351098|uniprotkb:Q6IBR1|uniprotkb:A8MZ91|uniprotkb:Q9UKH1|uniprotkb:B5BU10|uniprotkb:D3DS33|ensembl:ENSP00000319169|uniprotkb:A8MTP3|uniprotkb:B4DX49|uniprotkb:B4DY30|uniprotkb:E2QRE7 psi-mi:spt5h_human(display_long)|uniprotkb:DRB sensitivity-inducing factor large subunit(gene name synonym)|uniprotkb:DRB sensitivity-inducing factor 160 kDa subunit(gene name synonym)|uniprotkb:Tat-cotransactivator 1 protein(gene name synonym)|uniprotkb:SUPT5H(gene name)|psi-mi:SUPT5H(display_short)|uniprotkb:SPT5(gene name synonym)|uniprotkb:SPT5H(gene name synonym) psi-mi:anm5_human(display_long)|uniprotkb:PRMT5(gene name)|psi-mi:PRMT5(display_short)|uniprotkb:IBP72(gene name synonym)|uniprotkb:JBP1(gene name synonym)|uniprotkb:HRMT1L5(gene name synonym)|uniprotkb:Shk1 kinase-binding protein 1 homolog(gene name synonym)|uniprotkb:Jak-binding protein 1(gene name synonym)|uniprotkb:72 kDa ICln-binding protein(gene name synonym)|uniprotkb:SKB1(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485578|imex:IM-26985-513 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124296.1|refseq:NP_001124297.1|refseq:NP_003160.2|refseq:NP_001104490.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019899"(enzyme binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032785"(negative regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|ensembl:ENSG00000196235(gene)|ensembl:ENST00000432763(transcript)|ensembl:ENST00000598725(transcript)|ensembl:ENST00000599117(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|interpro:IPR041980|mint:O00267|rcsb pdb:2DO3|rcsb pdb:2E6Z|rcsb pdb:2E70|rcsb pdb:3H7H|rcsb pdb:4L1U|rcsb pdb:5OHO|rcsb pdb:5OHQ|rcsb pdb:5OIK|rcsb pdb:5U98|rcsb pdb:6EQY|rcsb pdb:6ER0|rcsb pdb:6GMH|rcsb pdb:6GML|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-75955|reactome:R-HSA-77075|refseq:NP_001306920.1|refseq:NP_001306919.1|dip:DIP-29014N refseq:NP_001034708.1|refseq:NP_006100.2|refseq:NP_001269882.1|refseq:NP_001269884.1|refseq:NP_001269885.1|ensembl:ENSG00000100462(gene)|ensembl:ENST00000324366(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000785"(chromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006353"(DNA-templated transcription, termination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0034709"(methylosome)|go:"GO:0034969"(histone arginine methylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035243"(protein-arginine omega-N symmetric methyltransferase activity)|go:"GO:0035246"(peptidyl-arginine N-methylation)|go:"GO:0042118"(endothelial cell activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0044030"(regulation of DNA methylation)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070888"(E-box binding)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0097421"(liver regeneration)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR007857(Skb1 methyltransferase)|interpro:IPR025799|interpro:IPR029063|interpro:IPR035075|interpro:IPR035247|interpro:IPR035248|mint:O14744|rcsb pdb:4GQB|rcsb pdb:4X60|rcsb pdb:4X61|rcsb pdb:4X63|rcsb pdb:5C9Z|rcsb pdb:5EMJ|rcsb pdb:5EMK|rcsb pdb:5EML|rcsb pdb:5EMM|rcsb pdb:5FA5|rcsb pdb:6CKC|rcsb pdb:6K1S|rcsb pdb:6RLL|rcsb pdb:6RLQ|rcsb pdb:6UGH|rcsb pdb:6UXX|rcsb pdb:6UXY|rcsb pdb:6V0N|rcsb pdb:6V0O|rcsb pdb:6V0P|rcsb pdb:7KIB|rcsb pdb:7KIC|rcsb pdb:7KID|rcsb pdb:7L1G|rcsb pdb:7M05|reactome:R-HSA-191859|reactome:R-HSA-3214858|reactome:R-HSA-6804760|go:"GO:1904992"(positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway)|dip:DIP-33172N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8VodOhZyrmNy3xxDTTsB8KugN849606 rogid:EwePjCDiU/fiuKOO+wnoYQ8I57I9606 rigid:yO+hmt/a82GPodA5lPe7rPcp62E false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00267 uniprotkb:P62314 intact:EBI-710464|ensembl:ENSP00000404029|ensembl:ENSP00000469090|ensembl:ENSP00000470252|uniprotkb:O43279|uniprotkb:Q59G52|uniprotkb:Q99639 intact:EBI-372177|uniprotkb:P13641|uniprotkb:B5BTZ1|ensembl:ENSP00000300413 psi-mi:spt5h_human(display_long)|uniprotkb:DRB sensitivity-inducing factor large subunit(gene name synonym)|uniprotkb:DRB sensitivity-inducing factor 160 kDa subunit(gene name synonym)|uniprotkb:Tat-cotransactivator 1 protein(gene name synonym)|uniprotkb:SUPT5H(gene name)|psi-mi:SUPT5H(display_short)|uniprotkb:SPT5(gene name synonym)|uniprotkb:SPT5H(gene name synonym) psi-mi:smd1_human(display_long)|uniprotkb:SNRPD1(gene name)|psi-mi:SNRPD1(display_short)|uniprotkb:snRNP core protein D1(gene name synonym)|uniprotkb:Sm-D autoantigen(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485578|imex:IM-26985-513 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124296.1|refseq:NP_001124297.1|refseq:NP_003160.2|refseq:NP_001104490.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019899"(enzyme binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032785"(negative regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|ensembl:ENSG00000196235(gene)|ensembl:ENST00000432763(transcript)|ensembl:ENST00000598725(transcript)|ensembl:ENST00000599117(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|interpro:IPR041980|mint:O00267|rcsb pdb:2DO3|rcsb pdb:2E6Z|rcsb pdb:2E70|rcsb pdb:3H7H|rcsb pdb:4L1U|rcsb pdb:5OHO|rcsb pdb:5OHQ|rcsb pdb:5OIK|rcsb pdb:5U98|rcsb pdb:6EQY|rcsb pdb:6ER0|rcsb pdb:6GMH|rcsb pdb:6GML|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-75955|reactome:R-HSA-77075|refseq:NP_001306920.1|refseq:NP_001306919.1|dip:DIP-29014N refseq:NP_001278845.1|refseq:NP_008869.1|ensembl:ENSG00000167088(gene)|ensembl:ENST00000300413(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005685"(U1 snRNP)|go:"GO:0005686"(U2 snRNP)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005829"(cytosol)|go:"GO:0008380"(RNA splicing)|go:"GO:0030532"(small nuclear ribonucleoprotein complex)|go:"GO:0034709"(methylosome)|go:"GO:0034715"(pICln-Sm protein complex)|go:"GO:0034719"(SMN-Sm protein complex)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097526"(spliceosomal tri-snRNP complex)|go:"GO:1990446"(U1 snRNP binding)|interpro:IPR001163(Like-Sm ribonucleoprotein, core)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|go:"GO:0000243"(commitment complex)|interpro:IPR027141|interpro:IPR034102|mint:P62314|rcsb pdb:1B34|rcsb pdb:3CW1|rcsb pdb:3JCR|rcsb pdb:3PGW|rcsb pdb:4F7U|rcsb pdb:4PJO|go:"GO:0000245"(spliceosomal complex assembly)|rcsb pdb:4V98|rcsb pdb:4WZJ|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5XJL|rcsb pdb:5XJQ|go:"GO:0000387"(spliceosomal snRNP assembly)|rcsb pdb:5XJR|rcsb pdb:5XJS|rcsb pdb:5XJT|rcsb pdb:5XJU|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6Y53|rcsb pdb:6Y5Q|rcsb pdb:7A5P|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7B0Y|rcsb pdb:7DVQ|reactome:R-HSA-191859|reactome:R-HSA-72163|reactome:R-HSA-72165|dip:DIP-31207N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8VodOhZyrmNy3xxDTTsB8KugN849606 rogid:bfXwsV+IOjDPCoOJOoMQgECyiII9606 rigid:yO+hmt/a82GPodA5lPe7rPcp62E false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00267 uniprotkb:Q9BQA1 intact:EBI-710464|ensembl:ENSP00000404029|ensembl:ENSP00000469090|ensembl:ENSP00000470252|uniprotkb:O43279|uniprotkb:Q59G52|uniprotkb:Q99639 intact:EBI-1237307|uniprotkb:B3KMW6|uniprotkb:Q96GK4|uniprotkb:Q9BWY3|uniprotkb:Q3LID2|uniprotkb:Q53FU2|uniprotkb:Q6JZZ5|uniprotkb:B4DP38|ensembl:ENSP00000235090 psi-mi:spt5h_human(display_long)|uniprotkb:DRB sensitivity-inducing factor large subunit(gene name synonym)|uniprotkb:DRB sensitivity-inducing factor 160 kDa subunit(gene name synonym)|uniprotkb:Tat-cotransactivator 1 protein(gene name synonym)|uniprotkb:SUPT5H(gene name)|psi-mi:SUPT5H(display_short)|uniprotkb:SPT5(gene name synonym)|uniprotkb:SPT5H(gene name synonym) psi-mi:mep50_human(display_long)|uniprotkb:WDR77(gene name)|psi-mi:WDR77(display_short)|uniprotkb:MEP50(gene name synonym)|uniprotkb:WD repeat-containing protein 77(gene name synonym)|uniprotkb:Androgen receptor cofactor p44(gene name synonym)|uniprotkb:p44/Mep50(gene name synonym)|uniprotkb:HKMT1069(orf name)|uniprotkb:Nbla10071(orf name)|uniprotkb:WD45(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485578|imex:IM-26985-513 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124296.1|refseq:NP_001124297.1|refseq:NP_003160.2|refseq:NP_001104490.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019899"(enzyme binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032785"(negative regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|ensembl:ENSG00000196235(gene)|ensembl:ENST00000432763(transcript)|ensembl:ENST00000598725(transcript)|ensembl:ENST00000599117(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|interpro:IPR041980|mint:O00267|rcsb pdb:2DO3|rcsb pdb:2E6Z|rcsb pdb:2E70|rcsb pdb:3H7H|rcsb pdb:4L1U|rcsb pdb:5OHO|rcsb pdb:5OHQ|rcsb pdb:5OIK|rcsb pdb:5U98|rcsb pdb:6EQY|rcsb pdb:6ER0|rcsb pdb:6GMH|rcsb pdb:6GML|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-75955|reactome:R-HSA-77075|refseq:NP_001306920.1|refseq:NP_001306919.1|dip:DIP-29014N refseq:NP_077007.1|refseq:NP_001303991.1|refseq:NP_001303992.1|refseq:NP_001303993.1|dip:DIP-38172N|ensembl:ENSG00000116455(gene)|ensembl:ENST00000235090(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007315"(pole plasm assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0034709"(methylosome)|go:"GO:0045495"(pole plasm)|go:"GO:0060528"(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:"GO:0060770"(negative regulation of epithelial cell proliferation involved in prostate gland development)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:Q9BQA1|rcsb pdb:4GQB|rcsb pdb:4X60|rcsb pdb:4X61|rcsb pdb:4X63|rcsb pdb:5C9Z|rcsb pdb:5EMJ|rcsb pdb:5EMK|rcsb pdb:5EML|rcsb pdb:5EMM|rcsb pdb:5FA5|rcsb pdb:6CKC|rcsb pdb:6K1S|rcsb pdb:6RLL|rcsb pdb:6RLQ|rcsb pdb:6UGH|rcsb pdb:6UXX|rcsb pdb:6UXY|rcsb pdb:6V0N|rcsb pdb:6V0O|rcsb pdb:6V0P|rcsb pdb:7KIB|rcsb pdb:7KIC|rcsb pdb:7KID|rcsb pdb:7L1G|rcsb pdb:7M05|reactome:R-HSA-191859|reactome:R-HSA-3214858 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8VodOhZyrmNy3xxDTTsB8KugN849606 rogid:0q4wunYtHalObC8r1wphhelIpr49606 rigid:yO+hmt/a82GPodA5lPe7rPcp62E false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00267 uniprotkb:Q99417 intact:EBI-710464|ensembl:ENSP00000404029|ensembl:ENSP00000469090|ensembl:ENSP00000470252|uniprotkb:O43279|uniprotkb:Q59G52|uniprotkb:Q99639 intact:EBI-716185|intact:EBI-2559925|uniprotkb:Q5TA64|uniprotkb:Q96HE2|uniprotkb:B2R4N0|ensembl:ENSP00000380702 psi-mi:spt5h_human(display_long)|uniprotkb:DRB sensitivity-inducing factor large subunit(gene name synonym)|uniprotkb:DRB sensitivity-inducing factor 160 kDa subunit(gene name synonym)|uniprotkb:Tat-cotransactivator 1 protein(gene name synonym)|uniprotkb:SUPT5H(gene name)|psi-mi:SUPT5H(display_short)|uniprotkb:SPT5(gene name synonym)|uniprotkb:SPT5H(gene name synonym) psi-mi:mycbp_human(display_long)|uniprotkb:Associate of Myc 1(gene name synonym)|uniprotkb:MYCBP(gene name)|psi-mi:MYCBP(display_short)|uniprotkb:AMY1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485578|imex:IM-26985-513 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124296.1|refseq:NP_001124297.1|refseq:NP_003160.2|refseq:NP_001104490.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019899"(enzyme binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032785"(negative regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|ensembl:ENSG00000196235(gene)|ensembl:ENST00000432763(transcript)|ensembl:ENST00000598725(transcript)|ensembl:ENST00000599117(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|interpro:IPR041980|mint:O00267|rcsb pdb:2DO3|rcsb pdb:2E6Z|rcsb pdb:2E70|rcsb pdb:3H7H|rcsb pdb:4L1U|rcsb pdb:5OHO|rcsb pdb:5OHQ|rcsb pdb:5OIK|rcsb pdb:5U98|rcsb pdb:6EQY|rcsb pdb:6ER0|rcsb pdb:6GMH|rcsb pdb:6GML|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-75955|reactome:R-HSA-77075|refseq:NP_001306920.1|refseq:NP_001306919.1|dip:DIP-29014N refseq:NP_036465.2|ensembl:ENSG00000214114(gene)|ensembl:ENST00000397572(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007283"(spermatogenesis)|interpro:IPR026060|mint:Q99417|rcsb pdb:2YY0 - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8VodOhZyrmNy3xxDTTsB8KugN849606 rogid:jIStn1A10DDkgTuwVeKpDPJ6tIs9606 rigid:yO+hmt/a82GPodA5lPe7rPcp62E false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00267 uniprotkb:P60510 intact:EBI-710464|ensembl:ENSP00000404029|ensembl:ENSP00000469090|ensembl:ENSP00000470252|uniprotkb:O43279|uniprotkb:Q59G52|uniprotkb:Q99639 intact:EBI-1046072|uniprotkb:P33172|ensembl:ENSP00000279387|ensembl:ENSP00000455995 psi-mi:spt5h_human(display_long)|uniprotkb:DRB sensitivity-inducing factor large subunit(gene name synonym)|uniprotkb:DRB sensitivity-inducing factor 160 kDa subunit(gene name synonym)|uniprotkb:Tat-cotransactivator 1 protein(gene name synonym)|uniprotkb:SUPT5H(gene name)|psi-mi:SUPT5H(display_short)|uniprotkb:SPT5(gene name synonym)|uniprotkb:SPT5H(gene name synonym) psi-mi:pp4c_human(display_long)|uniprotkb:Protein phosphatase X(gene name synonym)|uniprotkb:PPP4C(gene name)|psi-mi:PPP4C(display_short)|uniprotkb:PPP4(gene name synonym)|uniprotkb:PPX(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485578|imex:IM-26985-513 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124296.1|refseq:NP_001124297.1|refseq:NP_003160.2|refseq:NP_001104490.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019899"(enzyme binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032785"(negative regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|ensembl:ENSG00000196235(gene)|ensembl:ENST00000432763(transcript)|ensembl:ENST00000598725(transcript)|ensembl:ENST00000599117(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|interpro:IPR041980|mint:O00267|rcsb pdb:2DO3|rcsb pdb:2E6Z|rcsb pdb:2E70|rcsb pdb:3H7H|rcsb pdb:4L1U|rcsb pdb:5OHO|rcsb pdb:5OHQ|rcsb pdb:5OIK|rcsb pdb:5U98|rcsb pdb:6EQY|rcsb pdb:6ER0|rcsb pdb:6GMH|rcsb pdb:6GML|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-75955|reactome:R-HSA-77075|refseq:NP_001306920.1|refseq:NP_001306919.1|dip:DIP-29014N refseq:NP_002711.1|refseq:NP_001290432.1|refseq:NP_001290433.1|refseq:NP_001290435.1|refseq:NP_001290436.1|ensembl:ENSG00000149923(gene)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|mint:P60510|reactome:R-HSA-5693607|ensembl:ENST00000279387(transcript)|ensembl:ENST00000561610(transcript)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010569"(regulation of double-strand break repair via homologous recombination)|go:"GO:0030289"(protein phosphatase 4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase) - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8VodOhZyrmNy3xxDTTsB8KugN849606 rogid:1x3NwIpQ/T3bO/yHgAZUDqNV4989606 rigid:yO+hmt/a82GPodA5lPe7rPcp62E false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O00267 uniprotkb:P63272 intact:EBI-710464|ensembl:ENSP00000404029|ensembl:ENSP00000469090|ensembl:ENSP00000470252|uniprotkb:O43279|uniprotkb:Q59G52|uniprotkb:Q99639 intact:EBI-727250|uniprotkb:Q16550|uniprotkb:Q62387|uniprotkb:Q6ZP89|uniprotkb:B2R4X8|uniprotkb:D3DTZ4|ensembl:ENSP00000225504|ensembl:ENSP00000462670 psi-mi:spt5h_human(display_long)|uniprotkb:DRB sensitivity-inducing factor large subunit(gene name synonym)|uniprotkb:DRB sensitivity-inducing factor 160 kDa subunit(gene name synonym)|uniprotkb:Tat-cotransactivator 1 protein(gene name synonym)|uniprotkb:SUPT5H(gene name)|psi-mi:SUPT5H(display_short)|uniprotkb:SPT5(gene name synonym)|uniprotkb:SPT5H(gene name synonym) psi-mi:spt4h_human(display_long)|uniprotkb:DRB sensitivity-inducing factor small subunit(gene name synonym)|uniprotkb:DRB sensitivity-inducing factor 14 kDa subunit(gene name synonym)|uniprotkb:SUPT4H1(gene name)|psi-mi:SUPT4H1(display_short)|uniprotkb:SPT4H(gene name synonym)|uniprotkb:SUPT4H(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485578|imex:IM-26985-513 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001124296.1|refseq:NP_001124297.1|refseq:NP_003160.2|refseq:NP_001104490.1|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019899"(enzyme binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032785"(negative regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|ensembl:ENSG00000196235(gene)|ensembl:ENST00000432763(transcript)|ensembl:ENST00000598725(transcript)|ensembl:ENST00000599117(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:1900364"(negative regulation of mRNA polyadenylation)|interpro:IPR005100(Supt5 repeat)|interpro:IPR005824(KOW)|interpro:IPR006645(Transcription antitermination protein, NusG, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR017071(Transcription elongation factor Spt5)|interpro:IPR022581|interpro:IPR024945|interpro:IPR036735|interpro:IPR039385|interpro:IPR039659|interpro:IPR041973|interpro:IPR041975|interpro:IPR041976|interpro:IPR041977|interpro:IPR041978|interpro:IPR041980|mint:O00267|rcsb pdb:2DO3|rcsb pdb:2E6Z|rcsb pdb:2E70|rcsb pdb:3H7H|rcsb pdb:4L1U|rcsb pdb:5OHO|rcsb pdb:5OHQ|rcsb pdb:5OIK|rcsb pdb:5U98|rcsb pdb:6EQY|rcsb pdb:6ER0|rcsb pdb:6GMH|rcsb pdb:6GML|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167160|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-72086|reactome:R-HSA-75955|reactome:R-HSA-77075|refseq:NP_001306920.1|refseq:NP_001306919.1|dip:DIP-29014N refseq:NP_003159.1|ensembl:ENSG00000213246(gene)|ensembl:ENST00000225504(transcript)|ensembl:ENST00000580947(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006397"(mRNA processing)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032044"(DSIF complex)|go:"GO:0032785"(negative regulation of DNA-templated transcription, elongation)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|interpro:IPR009287(Transcription initiation Spt4)|interpro:IPR022800|interpro:IPR029040|interpro:IPR038510|mint:P63272|rcsb pdb:3H7H|rcsb pdb:5OIK|rcsb pdb:6GMH|rcsb pdb:6GML|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-113418|reactome:R-HSA-167152|reactome:R-HSA-167158|reactome:R-HSA-167200|reactome:R-HSA-167238|reactome:R-HSA-167242|reactome:R-HSA-167243|reactome:R-HSA-167246|reactome:R-HSA-167287|reactome:R-HSA-167290|reactome:R-HSA-674695|reactome:R-HSA-6796648|reactome:R-HSA-6807505|reactome:R-HSA-75955|dip:DIP-40644N - - comment:"author score: 322" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8VodOhZyrmNy3xxDTTsB8KugN849606 rogid:dz+Mu8lTSRS/nIQ+RUKWIiJAwTE9606 rigid:yO+hmt/a82GPodA5lPe7rPcp62E false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15022 uniprotkb:P68431 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 intact:EBI-79722|ensembl:ENSP00000352252|ensembl:ENSP00000358160|ensembl:ENSP00000366999|ensembl:ENSP00000480826|ensembl:ENSP00000482271|ensembl:ENSP00000483283|ensembl:ENSP00000484095|ensembl:ENSP00000484638|ensembl:ENSP00000484658|ensembl:ENSP00000484841|ensembl:ENSP00000489282|intact:EBI-1560041|uniprotkb:A0PJT7|uniprotkb:P02295|uniprotkb:P02296|uniprotkb:P16106|uniprotkb:Q6ISV8|uniprotkb:Q6NWP8|uniprotkb:Q6NWP9|uniprotkb:Q6NXU4|uniprotkb:Q71DJ3|uniprotkb:Q93081|uniprotkb:A5PLR1 psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:h31_human(display_long)|uniprotkb:H3FA(gene name synonym)|uniprotkb:H3FL(gene name synonym)|uniprotkb:H3FD(gene name synonym)|uniprotkb:H3FI(gene name synonym)|uniprotkb:H3FH(gene name synonym)|uniprotkb:H3FK(gene name synonym)|uniprotkb:H3FF(gene name synonym)|uniprotkb:H3FJ(gene name synonym)|uniprotkb:H3FB(gene name synonym)|uniprotkb:Histone H3/a(gene name synonym)|uniprotkb:Histone H3/b(gene name synonym)|uniprotkb:Histone H3/c(gene name synonym)|uniprotkb:Histone H3/d(gene name synonym)|uniprotkb:Histone H3/f(gene name synonym)|uniprotkb:Histone H3/h(gene name synonym)|uniprotkb:Histone H3/i(gene name synonym)|uniprotkb:Histone H3/j(gene name synonym)|uniprotkb:Histone H3/k(gene name synonym)|uniprotkb:Histone H3/l(gene name synonym)|uniprotkb:H3C1(gene name)|psi-mi:H3C1(display_short)|uniprotkb:HIST1H3A(gene name synonym)|uniprotkb:H3C2(gene name)|psi-mi:H3C2(display_short)|uniprotkb:HIST1H3B(gene name synonym)|uniprotkb:H3C3(gene name)|psi-mi:H3C3(display_short)|uniprotkb:H3FC HIST1H3C(gene name synonym)|uniprotkb:H3C4(gene name)|psi-mi:H3C4(display_short)|uniprotkb:HIST1H3D(gene name synonym)|uniprotkb:H3C6(gene name)|psi-mi:H3C6(display_short)|uniprotkb:HIST1H3E(gene name synonym)|uniprotkb:H3C7(gene name)|psi-mi:H3C7(display_short)|uniprotkb:HIST1H3F(gene name synonym)|uniprotkb:H3C8(gene name)|psi-mi:H3C8(display_short)|uniprotkb:HIST1H3G(gene name synonym)|uniprotkb:H3C10(gene name)|psi-mi:H3C10(display_short)|uniprotkb:HIST1H3H(gene name synonym)|uniprotkb:H3C11(gene name)|psi-mi:H3C11(display_short)|uniprotkb:HIST1H3I(gene name synonym)|uniprotkb:H3C12(gene name)|psi-mi:H3C12(display_short)|uniprotkb:HIST1H3J(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485716|imex:IM-26985-213 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421 rcsb pdb:4TN7|rcsb pdb:4U68|rcsb pdb:4UP0|rcsb pdb:4UY4|rcsb pdb:4X3K|rcsb pdb:4Y6L|rcsb pdb:4YHP|rcsb pdb:4YHZ|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z0R|rcsb pdb:4Z2M|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:4QBS|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B31|rcsb pdb:5C11|rcsb pdb:5C13|rcsb pdb:5C3I|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5D6Y|rcsb pdb:5DAH|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5FFV|rcsb pdb:5GH9|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5H6Q|rcsb pdb:5H6R|rcsb pdb:5HJB|rcsb pdb:5HJC|rcsb pdb:5HJD|rcsb pdb:5HYN|rcsb pdb:5IQL|rcsb pdb:5J3V|rcsb pdb:5J9S|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5B2J|rcsb pdb:5JRG|rcsb pdb:5KJH|rcsb pdb:5KJI|rcsb pdb:5KKL|rcsb pdb:5LUG|rcsb pdb:5M5G|rcsb pdb:5MR8|rcsb pdb:5NNC|rcsb pdb:5OY3|rcsb pdb:5SVX|rcsb pdb:5SVY|rcsb pdb:5SZB|rcsb pdb:5SZC|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5T1G|rcsb pdb:5T1I|rcsb pdb:5T8R|rcsb pdb:5TBN|rcsb pdb:5TDR|rcsb pdb:5TDW|rcsb pdb:5U2J|rcsb pdb:5V21|rcsb pdb:5V22|rcsb pdb:5VA6|rcsb pdb:5VAB|rcsb pdb:5VGE|rcsb pdb:5VNB|rcsb pdb:5NND|rcsb pdb:5WLE|rcsb pdb:5WVO|rcsb pdb:5WXG|rcsb pdb:5WXH|rcsb pdb:5WYI|rcsb pdb:5X60|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5XFQ|rcsb pdb:5XFR|rcsb pdb:5XNV|rcsb pdb:5XTZ|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Y20|rcsb pdb:5Y2F|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:6AXJ|rcsb pdb:6AZE|rcsb pdb:6BHD|rcsb pdb:6BHE|rcsb pdb:6BHG|rcsb pdb:6BHH|rcsb pdb:6BHI|rcsb pdb:6D07|rcsb pdb:6D08|rcsb pdb:6E83|rcsb pdb:6E86|rcsb pdb:5WFC|rcsb pdb:6F6D|rcsb pdb:6HTS|rcsb pdb:6IEU|rcsb pdb:6IIS|rcsb pdb:6IIT|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6JXD|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6LS6|rcsb pdb:6LSD|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MIL|rcsb pdb:6MIM|rcsb pdb:6MIN|rcsb pdb:6MIO|rcsb pdb:6MIQ|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6HKT|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2H|rcsb pdb:6V2K|rcsb pdb:6V3N|rcsb pdb:6V41|rcsb pdb:6V92|rcsb pdb:6VIL|rcsb pdb:6WAV|rcsb pdb:6WW4|rcsb pdb:6YIF|rcsb pdb:6YIH|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:6R92|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7KLR|rcsb pdb:7LYC|reactome:R-HSA-1266695|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|ensembl:ENSG00000197153(gene)|ensembl:ENSG00000197409(gene)|ensembl:ENSG00000273983(gene)|ensembl:ENSG00000274750(gene)|ensembl:ENSG00000275379(gene)|ensembl:ENSG00000275714(gene)|ensembl:ENSG00000277775(gene)|ensembl:ENSG00000278828(gene)|ensembl:ENSG00000286522(gene)|ensembl:ENSG00000287080(gene)|ensembl:ENST00000356476(transcript)|ensembl:ENST00000359303(transcript)|ensembl:ENST00000369163(transcript)|ensembl:ENST00000612966(transcript)|ensembl:ENST00000613854(transcript)|ensembl:ENST00000614378(transcript)|ensembl:ENST00000614911(transcript)|ensembl:ENST00000616365(transcript)|ensembl:ENST00000618052(transcript)|ensembl:ENST00000621411(transcript)|ensembl:ENST00000634733(transcript)|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-3247509|reactome:R-HSA-9710421|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060968"(obsolete regulation of gene silencing)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|interpro:IPR009072(Histone-fold)|mint:P68431|rcsb pdb:1CS9|rcsb pdb:1CT6|rcsb pdb:1O9S|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|rcsb pdb:1Q3L|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|rcsb pdb:2B2T|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|rcsb pdb:2B2U|rcsb pdb:2B2V|rcsb pdb:2B2W|rcsb pdb:2C1J|rcsb pdb:2C1N|go:"GO:0016020"(membrane)|rcsb pdb:2CO0|rcsb pdb:2CV5|rcsb pdb:2FSA|rcsb pdb:2KWJ|rcsb pdb:2KWK|rcsb pdb:2L75|rcsb pdb:2LBM|rcsb pdb:2LGG|rcsb pdb:2M0O|reactome:R-HSA-983231|reactome:R-HSA-977225|rcsb pdb:2NDG|rcsb pdb:2OQ6|rcsb pdb:2OT7|rcsb pdb:2OX0|rcsb pdb:2RI7|rcsb pdb:2RR4|rcsb pdb:2UXN|rcsb pdb:2V85|rcsb pdb:2V89|rcsb pdb:2VNF|rcsb pdb:2VPG|rcsb pdb:2X0L|rcsb pdb:3A1B|rcsb pdb:2NDF|rcsb pdb:3AFA|rcsb pdb:3AVR|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3B95|rcsb pdb:3FDT|rcsb pdb:3KMT|rcsb pdb:3KQI|rcsb pdb:3LQI|rcsb pdb:3LQJ|rcsb pdb:3MP1|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O37|rcsb pdb:3QJ6|rcsb pdb:3RIG|rcsb pdb:3RIY|rcsb pdb:3SOU|rcsb pdb:3SOW|rcsb pdb:3U31|rcsb pdb:3U3D|rcsb pdb:3U4S|rcsb pdb:3U5N|rcsb pdb:3U5O|rcsb pdb:3AZK|rcsb pdb:3U5P|rcsb pdb:3UEE|rcsb pdb:3UEF|rcsb pdb:3UII|rcsb pdb:3UIK|rcsb pdb:3V43|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:3ZG6|rcsb pdb:3ZVY|rcsb pdb:4A0J|rcsb pdb:4A0N|rcsb pdb:4A7J|rcsb pdb:3UIG|rcsb pdb:4BD3|rcsb pdb:4C1Q|rcsb pdb:4F4U|rcsb pdb:4F56|rcsb pdb:4FWF|rcsb pdb:4HON|rcsb pdb:4I51|rcsb pdb:4L7X|rcsb pdb:4LK9|rcsb pdb:4LKA|rcsb pdb:4LLB|rcsb pdb:4LXL|rcsb pdb:4N4H|rcsb pdb:4QBQ|rcsb pdb:4QBR|refseq:NP_003520.1|refseq:NP_003521.2|refseq:NP_003522.1|refseq:NP_003523.1|refseq:NP_003524.1|refseq:NP_003525.1|refseq:NP_003526.1|refseq:NP_003527.1|refseq:NP_003528.1|refseq:NP_066298.1|dip:DIP-29371N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 rogid:ood0OohxZHuhsWZtO7U7GMc+LwM9606 rigid:gixynJ/5aEKOhfqbEWHHYJuIIyw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15022 uniprotkb:Q71DI3 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 intact:EBI-750650|uniprotkb:A2BDF6|uniprotkb:A6NFS4|uniprotkb:Q6B053|ensembl:ENSP00000333277|ensembl:ENSP00000358154|ensembl:ENSP00000385479 psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:h32_human(display_long)|uniprotkb:H3C13(gene name)|psi-mi:H3C13(display_short)|uniprotkb:H3C14(gene name)|psi-mi:H3C14(display_short)|uniprotkb:H3C15(gene name)|psi-mi:H3C15(display_short)|uniprotkb:H3-clustered histone 13(gene name synonym)|uniprotkb:H3-clustered histone 14(gene name synonym)|uniprotkb:H3-clustered histone 15(gene name synonym)|uniprotkb:H3F2(gene name synonym)|uniprotkb:H3FM(gene name synonym)|uniprotkb:HIST2H3A(gene name synonym)|uniprotkb:HIST2H3C(gene name synonym)|uniprotkb:HIST2H3D(gene name synonym)|uniprotkb:Histone H3/m(gene name synonym)|uniprotkb:Histone H3/o(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485716|imex:IM-26985-213 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421 refseq:NP_001005464.1|refseq:NP_001116847.1|refseq:NP_066403.2|dip:DIP-48606N|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|rcsb pdb:7BU9|rcsb pdb:7JO9|rcsb pdb:7JOA|reactome:R-HSA-3214858|reactome:R-HSA-3247509|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-983231|rcsb pdb:7JZV|reactome:R-HSA-1266695|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|ensembl:ENSG00000183598(gene)|ensembl:ENSG00000203811(gene)|ensembl:ENSG00000203852(gene)|ensembl:ENST00000331491(transcript)|ensembl:ENST00000369158(transcript)|ensembl:ENST00000403683(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:Q71DI3|rcsb pdb:2IIJ|rcsb pdb:2X4W|rcsb pdb:2X4X|rcsb pdb:2X4Y|rcsb pdb:3AV1|rcsb pdb:3DB3|rcsb pdb:3MO8|rcsb pdb:3QO2|rcsb pdb:3R93|rcsb pdb:4MZF|rcsb pdb:4MZG|rcsb pdb:4MZH|rcsb pdb:4OUC|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B40|rcsb pdb:5BO0|rcsb pdb:5CIU|rcsb pdb:5VAC|rcsb pdb:6ACE|rcsb pdb:6FML|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6Y5E|rcsb pdb:7BQZ - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 rogid:2TuVqWkeAnhHR4nrl0GNyUj1N3o9606 rigid:gixynJ/5aEKOhfqbEWHHYJuIIyw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15022 uniprotkb:Q6ZN18 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 intact:EBI-743256|ensembl:ENSP00000381840|uniprotkb:Q59FS5|uniprotkb:Q6ZN62|uniprotkb:Q96BG3 psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:aebp2_human(display_long)|uniprotkb:Adipocyte enhancer-binding protein 2(gene name synonym)|uniprotkb:AEBP2(gene name)|psi-mi:AEBP2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485716|imex:IM-26985-213 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421 ensembl:ENSG00000139154(gene)|interpro:IPR036236|ensembl:ENST00000398864(transcript)|go:"GO:0000785"(chromatin)|mint:Q6ZN18|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|refseq:NP_001107648.1|refseq:NP_694939.2|rcsb pdb:5WAI|rcsb pdb:5Y0U|rcsb pdb:5Y1U|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6WKR|rcsb pdb:7KSO|reactome:R-HSA-212300|reactome:R-HSA-3214841|refseq:NP_001253972.1|dip:DIP-58581N - - comment:"author score: 39" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 rogid:mOY+NOTaqJlXjW8v6D3YPnfnfBU9606 rigid:gixynJ/5aEKOhfqbEWHHYJuIIyw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15022 uniprotkb:Q16576 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 intact:EBI-352227|ensembl:ENSP00000369427|intact:EBI-3505029|uniprotkb:Q5JP00 psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:rbbp7_human(display_long)|uniprotkb:RBBP7(gene name)|psi-mi:RBBP7(display_short)|uniprotkb:RBAP46(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 7(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p46(gene name synonym)|uniprotkb:Histone acetyltransferase type B subunit 2(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP46(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485716|imex:IM-26985-213 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421 refseq:NP_002884.1|ensembl:ENST00000380087(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0016581"(NuRD complex)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0070370"(cellular heat acclimation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|interpro:IPR036322|mint:Q16576|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:7M3X|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8951664|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|ensembl:ENSG00000102054(gene)|refseq:NP_001185648.1|dip:DIP-436N - - comment:"author score: 41" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 rogid:qANLG0ui7jm3Uy4+IRnxR8Kir7c9606 rigid:gixynJ/5aEKOhfqbEWHHYJuIIyw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15022 uniprotkb:Q96DB5 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 intact:EBI-2564644|uniprotkb:A9UMZ8|uniprotkb:Q9Y398|ensembl:ENSP00000385927|uniprotkb:B4DNF5|uniprotkb:E7EVI2|uniprotkb:B4DZW6|uniprotkb:B5MC61|uniprotkb:C9JSC6 psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:rmd1_human(display_long)|uniprotkb:RMDN1(gene name)|psi-mi:RMDN1(display_short)|uniprotkb:FAM82B(gene name synonym)|uniprotkb:Protein FAM82B(gene name synonym)|uniprotkb:CGI-90(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485716|imex:IM-26985-213 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421 refseq:NP_001273648.1|refseq:NP_057117.2|refseq:NP_001304736.1|ensembl:ENSG00000176623(gene)|ensembl:ENST00000406452(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005876"(spindle microtubule)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0051315"(attachment of mitotic spindle microtubules to kinetochore)|go:"GO:0097431"(mitotic spindle pole)|interpro:IPR011990(Tetratricopeptide-like helical)|mint:Q96DB5|refseq:NP_001273636.1 - - comment:"author score: 64" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 rogid:EAYrDAOf2NP9wZLfqd3rmwSV5uc9606 rigid:gixynJ/5aEKOhfqbEWHHYJuIIyw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15022 uniprotkb:Q92800 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 intact:EBI-8830732|uniprotkb:B4E3R7|uniprotkb:O43287|uniprotkb:A6NCH6|uniprotkb:Q14459|uniprotkb:Q53XP3|uniprotkb:B4DSS2|uniprotkb:B4DIJ1|uniprotkb:B4DIZ7|ensembl:ENSP00000404658|ensembl:ENSP00000466924 psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:ezh1_human(display_long)|uniprotkb:ENX-2(gene name synonym)|uniprotkb:Enhancer of zeste homolog 1(gene name synonym)|uniprotkb:KIAA0388(gene name synonym)|uniprotkb:EZH1(gene name)|psi-mi:EZH1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485716|imex:IM-26985-213 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421 refseq:NP_001308008.1|refseq:NP_001308010.1|refseq:NP_001308011.1|refseq:NP_001982.2|dip:DIP-58580N|ensembl:ENSG00000108799(gene)|ensembl:ENST00000428826(transcript)|ensembl:ENST00000592743(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006348"|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0021766"(hippocampus development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070734"(histone H3-K27 methylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0031507"(heterochromatin assembly)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR021654|interpro:IPR001214(SET)|interpro:IPR026489|interpro:IPR033467|interpro:IPR032926|interpro:IPR041343|interpro:IPR041355|interpro:IPR044438|mint:Q92800|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP - - comment:"author score: 76" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 rogid:qp3eqBCgiaoA6VSSyqpW1d9YKN49606 rigid:gixynJ/5aEKOhfqbEWHHYJuIIyw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15022 uniprotkb:Q09028 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 intact:EBI-620823|uniprotkb:B4DRH0|ensembl:ENSP00000362592|uniprotkb:P31149|uniprotkb:Q53H02|uniprotkb:Q96BV9|uniprotkb:D3DPQ3|uniprotkb:B2R6G9 psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:rbbp4_human(display_long)|uniprotkb:Retinoblastoma-binding protein 4(gene name synonym)|uniprotkb:Retinoblastoma-binding protein p48(gene name synonym)|uniprotkb:Chromatin assembly factor 1 subunit C(gene name synonym)|uniprotkb:Chromatin assembly factor I p48 subunit(gene name synonym)|uniprotkb:Nucleosome-remodeling factor subunit RBAP48(gene name synonym)|uniprotkb:RBBP4(gene name)|psi-mi:RBBP4(display_short)|uniprotkb:RBAP48(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485716|imex:IM-26985-213 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421 ensembl:ENSG00000162521(gene)|ensembl:ENST00000373493(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006260"(DNA replication)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007049"(cell cycle)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016580"(Sin3 complex)|go:"GO:0016581"(NuRD complex)|go:"GO:0016589"(NURF complex)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043044"|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR022052|mint:Q09028|rcsb pdb:2XU7|rcsb pdb:3GFC|rcsb pdb:4PBY|rcsb pdb:4PBZ|rcsb pdb:4PC0|rcsb pdb:4R7A|rcsb pdb:5FXY|rcsb pdb:5VTB|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5XWR|rcsb pdb:5XXQ|rcsb pdb:5Y1U|rcsb pdb:6BW3|rcsb pdb:6BW4|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6G16|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:6ZRC|rcsb pdb:6ZRD|rcsb pdb:7AOA|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7M40|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-156711|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-427389|reactome:R-HSA-5617472|reactome:R-HSA-606279|reactome:R-HSA-6804758|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69656|reactome:R-HSA-73762|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9679191|reactome:R-HSA-9710421|interpro:IPR036322|refseq:NP_001128727.1|refseq:NP_001128728.1|refseq:NP_005601.1|dip:DIP-33495N - - comment:"author score: 82" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 rogid:CbyJMIjpW1A4sZijP0IGRYc8o4I9606 rigid:gixynJ/5aEKOhfqbEWHHYJuIIyw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15022 uniprotkb:O75530 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 intact:EBI-923794|intact:EBI-2839778|intact:EBI-1177693|uniprotkb:A8K7V5|uniprotkb:Q6NTH2|uniprotkb:Q7LDA5|uniprotkb:Q7LDG8|uniprotkb:Q86VV2|uniprotkb:Q9UNY7|uniprotkb:O00149|ensembl:ENSP00000263360|ensembl:ENSP00000500834 psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:eed_human(display_long)|uniprotkb:EED(gene name)|psi-mi:EED(display_short)|uniprotkb:WD protein associating with integrin cytoplasmic tails 1(gene name synonym)|uniprotkb:Embryonic ectoderm development protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485716|imex:IM-26985-213 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421 refseq:NP_003788.2|refseq:NP_001294936.1|dip:DIP-36673N|ensembl:ENSG00000074266(gene)|ensembl:ENST00000263360(transcript)|ensembl:ENST00000672825(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006342"|go:"GO:0008047"(enzyme activator activity)|go:"GO:0021510"(spinal cord development)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070734"(histone H3-K27 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|interpro:IPR037352|mint:O75530|rcsb pdb:3IIW|rcsb pdb:3IIY|rcsb pdb:3IJ0|rcsb pdb:3IJ1|rcsb pdb:3IJC|rcsb pdb:3JPX|rcsb pdb:3JZG|rcsb pdb:3JZH|rcsb pdb:3JZN|rcsb pdb:3K26|rcsb pdb:3K27|rcsb pdb:4W2R|rcsb pdb:4X3E|rcsb pdb:5GSA|rcsb pdb:5H13|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5K0M|rcsb pdb:5LS6|rcsb pdb:5TTW|rcsb pdb:5U5H|rcsb pdb:5U5K|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5U69|rcsb pdb:5U6D|rcsb pdb:5U8A|rcsb pdb:5U8F|rcsb pdb:5WG6|rcsb pdb:5WP3|rcsb pdb:5WUK|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6SFB|rcsb pdb:6SFC|rcsb pdb:6U4Y|rcsb pdb:6V3X|rcsb pdb:6V3Y|rcsb pdb:6W7F|rcsb pdb:6W7G|rcsb pdb:6WKR|rcsb pdb:6YVI|rcsb pdb:6YVJ|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|rcsb pdb:7KXT|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421 - - comment:"author score: 193" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 rogid:iivsQ4n2lmgM33PVY8WJFQXLnEA9606 rigid:gixynJ/5aEKOhfqbEWHHYJuIIyw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15022 uniprotkb:Q15910 intact:EBI-1264675|uniprotkb:Q96BD9|ensembl:ENSP00000316578 intact:EBI-530054|uniprotkb:Q15755|uniprotkb:Q92857|uniprotkb:B2RAQ1|uniprotkb:B3KS30|uniprotkb:B7Z1D6|uniprotkb:B7Z7L6|uniprotkb:Q96FI6|intact:EBI-746496|ensembl:ENSP00000419711|uniprotkb:Q75MG3 psi-mi:suz12_human(display_long)|uniprotkb:CHET9(gene name synonym)|uniprotkb:JJAZ1(gene name synonym)|uniprotkb:KIAA0160(gene name synonym)|uniprotkb:SUZ12(gene name)|psi-mi:SUZ12(display_short)|uniprotkb:Suppressor of zeste 12 protein homolog(gene name synonym)|uniprotkb:Joined to JAZF1 protein(gene name synonym)|uniprotkb:Chromatin precipitated E2F target 9 protein(gene name synonym) psi-mi:ezh2_human(display_long)|uniprotkb:KMT6(gene name synonym)|uniprotkb:Enhancer of zeste homolog 2(gene name synonym)|uniprotkb:ENX-1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 6(gene name synonym)|uniprotkb:EZH2(gene name)|psi-mi:EZH2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485716|imex:IM-26985-213 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) dip:DIP-38524N|refseq:NP_056170.2|ensembl:ENSG00000178691(gene)|ensembl:ENST00000322652(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0016604"(nuclear body)|go:"GO:0021510"(spinal cord development)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR019135|mint:Q15022|go:"GO:0031490"(chromatin DNA binding)|rcsb pdb:4W2R|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5WAI|rcsb pdb:5WAK|rcsb pdb:5WG6|rcsb pdb:6B3W|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6NQ3|rcsb pdb:6WKR|rcsb pdb:7AT8|rcsb pdb:7KSO|rcsb pdb:7KSR|rcsb pdb:7KTP|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-4551638|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|reactome:R-HSA-9710421 refseq:XP_011514186.1|refseq:NP_001190176.1|refseq:NP_001190177.1|refseq:NP_001190178.1|refseq:NP_004447.2|refseq:NP_694543.1|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051932"(synaptic transmission, GABAergic)|ensembl:ENSG00000106462(gene)|ensembl:ENST00000460911(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006306"(DNA methylation)|go:"GO:0006325"(chromatin organization)|go:"GO:0006348"|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0014834"(skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration)|go:"GO:0014898"(cardiac muscle hypertrophy in response to stress)|go:"GO:0016279"(protein-lysine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0021695"(cerebellar cortex development)|go:"GO:0021766"(hippocampus development)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034244"(negative regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035098"("ESC/E(Z) complex")|go:"GO:0035984"(cellular response to trichostatin A)|go:"GO:0036333"(hepatocyte homeostasis)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045120"(pronucleus)|go:"GO:0045202"(synapse)|go:"GO:0045605"(negative regulation of epidermal cell differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046976"("histone methyltransferase activity (H3-K27 specific)")|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048468"(cell development)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070314"(G1 to G0 transition)|go:"GO:0070878"(primary miRNA binding)|go:"GO:0071168"(protein localization to chromatin)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0097421"(liver regeneration)|go:"GO:0098532"(histone H3-K27 trimethylation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900016"(negative regulation of cytokine production involved in inflammatory response)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR021654|interpro:IPR026489|interpro:IPR033467|interpro:IPR041343|interpro:IPR041355|interpro:IPR044439|mint:Q15910|rcsb pdb:2C6V|rcsb pdb:4MI0|rcsb pdb:4MI5|rcsb pdb:5GSA|rcsb pdb:5H14|rcsb pdb:5H15|rcsb pdb:5H17|rcsb pdb:5H19|rcsb pdb:5H24|rcsb pdb:5H25|rcsb pdb:5HYN|rcsb pdb:5IJ7|rcsb pdb:5IJ8|rcsb pdb:5LS6|rcsb pdb:5U5T|rcsb pdb:5U62|rcsb pdb:5WG6|rcsb pdb:5WUK|rcsb pdb:6C23|rcsb pdb:6C24|rcsb pdb:6P5L|rcsb pdb:6U4Y|rcsb pdb:6WKR|rcsb pdb:7AT8|reactome:R-HSA-212300|reactome:R-HSA-2559580|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8943724|reactome:R-HSA-8953750|reactome:R-HSA-9609690|go:"GO:0070734"(histone H3-K27 methylation)|reactome:R-HSA-9710421|go:"GO:0048511"(rhythmic process)|dip:DIP-34002N - - comment:"author score: 212" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:7jhDQNr4267eYuG9wRUpTfGgT2g9606 rogid:ZjwjEGDmMsyQ/33rYN7PimxvcUk9606 rigid:gixynJ/5aEKOhfqbEWHHYJuIIyw false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86Y97 uniprotkb:P47914 intact:EBI-7960569|uniprotkb:Q8WZ10|uniprotkb:Q9BRZ6|intact:MINT-4776457|ensembl:ENSP00000255613 intact:EBI-714039|uniprotkb:Q6IPY3|ensembl:ENSP00000418346|ensembl:ENSP00000418868|ensembl:ENSP00000420673|ensembl:ENSP00000294189|ensembl:ENSP00000417048|ensembl:ENSP00000418153|uniprotkb:B2R4M8|uniprotkb:A8K0H3 psi-mi:kmt5c_human(display_long)|uniprotkb:[histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:[histone H4]-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:PP7130(orf name)|uniprotkb:KMT5C(gene name)|psi-mi:KMT5C(display_short)|uniprotkb:Lysine N-methyltransferase 5C(gene name synonym)|uniprotkb:Lysine-specific methyltransferase 5C(gene name synonym)|uniprotkb:SUV420H2(gene name synonym)|uniprotkb:Suppressor of variegation 4-20 homolog 2(gene name synonym) psi-mi:rl29_human(display_long)|uniprotkb:Cell surface heparin-binding protein HIP(gene name synonym)|uniprotkb:RPL29(gene name)|psi-mi:RPL29(display_short)|uniprotkb:Large ribosomal subunit protein eL29(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485635|imex:IM-26985-445 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011525717.1|refseq:NP_116090.2|refseq:XP_005259395.1|refseq:XP_006723505.1|ensembl:ENSG00000133247(gene)|ensembl:ENST00000255613(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006281"(DNA repair)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0034772"(histone H4-K20 dimethylation)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0042393"(histone binding)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0046872"(metal ion binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001214(SET)|interpro:IPR025790|interpro:IPR039977|interpro:IPR041938|interpro:IPR044425|mint:Q86Y97|rcsb pdb:3RQ4|reactome:R-HSA-3214841 ensembl:ENST00000294189(transcript)|ensembl:ENST00000466397(transcript)|ensembl:ENST00000475248(transcript)|ensembl:ENST00000479017(transcript)|ensembl:ENST00000492277(transcript)|ensembl:ENST00000495383(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0007566"(embryo implantation)|go:"GO:0008201"(heparin binding)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR002673(Ribosomal protein L29e)|mint:P47914|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|ensembl:ENSG00000162244(gene)|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_000983.1|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339 - function:"Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2)"|comment:mint comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:j6OmjKnEQkpMSoN3ok/kKPJMODM9606 rogid:XZUSMDDzycAi6QEXYbljXaeVg0U9606 rigid:kBc1NUlSoDsbe7yRuX0UGxl8f7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86Y97 uniprotkb:Q16769 intact:EBI-7960569|uniprotkb:Q8WZ10|uniprotkb:Q9BRZ6|intact:MINT-4776457|ensembl:ENSP00000255613 intact:EBI-2856807|uniprotkb:Q3KRG6|uniprotkb:Q16770|uniprotkb:Q53TR4|ensembl:ENSP00000344829 psi-mi:kmt5c_human(display_long)|uniprotkb:[histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:[histone H4]-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:PP7130(orf name)|uniprotkb:KMT5C(gene name)|psi-mi:KMT5C(display_short)|uniprotkb:Lysine N-methyltransferase 5C(gene name synonym)|uniprotkb:Lysine-specific methyltransferase 5C(gene name synonym)|uniprotkb:SUV420H2(gene name synonym)|uniprotkb:Suppressor of variegation 4-20 homolog 2(gene name synonym) psi-mi:qpct_human(display_long)|uniprotkb:QPCT(gene name)|psi-mi:QPCT(display_short)|uniprotkb:Glutaminyl cyclase(gene name synonym)|uniprotkb:Glutaminyl-tRNA cyclotransferase(gene name synonym)|uniprotkb:Glutamyl cyclase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485635|imex:IM-26985-445 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011525717.1|refseq:NP_116090.2|refseq:XP_005259395.1|refseq:XP_006723505.1|ensembl:ENSG00000133247(gene)|ensembl:ENST00000255613(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006281"(DNA repair)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0034772"(histone H4-K20 dimethylation)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0042393"(histone binding)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0046872"(metal ion binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001214(SET)|interpro:IPR025790|interpro:IPR039977|interpro:IPR041938|interpro:IPR044425|mint:Q86Y97|rcsb pdb:3RQ4|reactome:R-HSA-3214841 refseq:NP_036545.1|ensembl:ENSG00000115828(gene)|ensembl:ENST00000338415(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008235"(metalloexopeptidase activity)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016603"(glutaminyl-peptide cyclotransferase activity)|go:"GO:0017186"(peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase)|go:"GO:0035580"(specific granule lumen)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR007484(Peptidase M28)|interpro:IPR037457|interpro:IPR040234|mint:Q16769|rcsb pdb:1MOI|rcsb pdb:2AFM|rcsb pdb:2AFO|rcsb pdb:2AFS|rcsb pdb:2AFU|rcsb pdb:2AFW|rcsb pdb:2AFX|rcsb pdb:2AFZ|rcsb pdb:2ZED|rcsb pdb:2ZEE|rcsb pdb:2ZEF|rcsb pdb:2ZEG|rcsb pdb:2ZEH|rcsb pdb:2ZEL|rcsb pdb:2ZEM|rcsb pdb:2ZEN|rcsb pdb:2ZEO|rcsb pdb:2ZEP|rcsb pdb:3PBB|rcsb pdb:3PBE|rcsb pdb:3SI0|rcsb pdb:4YU9|rcsb pdb:4YWY|rcsb pdb:6YI1|rcsb pdb:6YJY|rcsb pdb:7COZ|rcsb pdb:7CP0|reactome:R-HSA-6798695|rcsb pdb:6GBX - function:"Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2)"|comment:mint comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:j6OmjKnEQkpMSoN3ok/kKPJMODM9606 rogid:P77dag9F4CgK4eLQHdFlYbz4Kxg9606 rigid:kBc1NUlSoDsbe7yRuX0UGxl8f7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86Y97 uniprotkb:Q969Q0 intact:EBI-7960569|uniprotkb:Q8WZ10|uniprotkb:Q9BRZ6|intact:MINT-4776457|ensembl:ENSP00000255613 intact:EBI-2877705|ensembl:ENSP00000346012|uniprotkb:Q3B7A5 psi-mi:kmt5c_human(display_long)|uniprotkb:[histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:[histone H4]-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:PP7130(orf name)|uniprotkb:KMT5C(gene name)|psi-mi:KMT5C(display_short)|uniprotkb:Lysine N-methyltransferase 5C(gene name synonym)|uniprotkb:Lysine-specific methyltransferase 5C(gene name synonym)|uniprotkb:SUV420H2(gene name synonym)|uniprotkb:Suppressor of variegation 4-20 homolog 2(gene name synonym) psi-mi:rl36l_human(display_long)|uniprotkb:RPL36AL(gene name)|psi-mi:RPL36AL(display_short)|uniprotkb:Large ribosomal subunit protein eL42-like(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485635|imex:IM-26985-445 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011525717.1|refseq:NP_116090.2|refseq:XP_005259395.1|refseq:XP_006723505.1|ensembl:ENSG00000133247(gene)|ensembl:ENST00000255613(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006281"(DNA repair)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0034772"(histone H4-K20 dimethylation)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0042393"(histone binding)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0046872"(metal ion binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001214(SET)|interpro:IPR025790|interpro:IPR039977|interpro:IPR041938|interpro:IPR044425|mint:Q86Y97|rcsb pdb:3RQ4|reactome:R-HSA-3214841 ensembl:ENSG00000165502(gene)|ensembl:ENST00000298289(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR000552(Ribosomal protein L44e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|mint:Q969Q0|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-9633012|refseq:NP_000992.1 - function:"Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2)"|comment:mint comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:j6OmjKnEQkpMSoN3ok/kKPJMODM9606 rogid:+jT5oFy79StEavkvHz6j/36g/qg9606 rigid:kBc1NUlSoDsbe7yRuX0UGxl8f7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86Y97 uniprotkb:Q96QC0 intact:EBI-7960569|uniprotkb:Q8WZ10|uniprotkb:Q9BRZ6|intact:MINT-4776457|ensembl:ENSP00000255613 intact:EBI-1210346|uniprotkb:O00405|ensembl:ENSP00000365694|ensembl:ENSP00000373080|ensembl:ENSP00000389299|ensembl:ENSP00000407181|ensembl:ENSP00000407310|ensembl:ENSP00000413554|ensembl:ENSP00000416060 psi-mi:kmt5c_human(display_long)|uniprotkb:[histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:[histone H4]-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:PP7130(orf name)|uniprotkb:KMT5C(gene name)|psi-mi:KMT5C(display_short)|uniprotkb:Lysine N-methyltransferase 5C(gene name synonym)|uniprotkb:Lysine-specific methyltransferase 5C(gene name synonym)|uniprotkb:SUV420H2(gene name synonym)|uniprotkb:Suppressor of variegation 4-20 homolog 2(gene name synonym) psi-mi:pp1ra_human(display_long)|uniprotkb:PPP1R10(gene name)|psi-mi:PPP1R10(display_short)|uniprotkb:CAT53(gene name synonym)|uniprotkb:FB19(gene name synonym)|uniprotkb:PNUTS(gene name synonym)|uniprotkb:Phosphatase 1 nuclear targeting subunit(gene name synonym)|uniprotkb:MHC class I region proline-rich protein CAT53(gene name synonym)|uniprotkb:Protein FB19(gene name synonym)|uniprotkb:PP1-binding protein of 114 kDa(gene name synonym)|uniprotkb:p99(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485635|imex:IM-26985-445 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011525717.1|refseq:NP_116090.2|refseq:XP_005259395.1|refseq:XP_006723505.1|ensembl:ENSG00000133247(gene)|ensembl:ENST00000255613(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006281"(DNA repair)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0034772"(histone H4-K20 dimethylation)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0042393"(histone binding)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0046872"(metal ion binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001214(SET)|interpro:IPR025790|interpro:IPR039977|interpro:IPR041938|interpro:IPR044425|mint:Q86Y97|rcsb pdb:3RQ4|reactome:R-HSA-3214841 refseq:XP_011513024.1|refseq:NP_002705.2|refseq:XP_006715193.1|refseq:XP_016866484.1|dip:DIP-39343N|ensembl:ENSG00000204569(gene)|ensembl:ENSG00000206489(gene)|ensembl:ENSG00000227804(gene)|ensembl:ENSG00000230995(gene)|ensembl:ENSG00000231737(gene)|ensembl:ENSG00000235291(gene)|ensembl:ENSG00000238104(gene)|ensembl:ENST00000376511(transcript)|ensembl:ENST00000383586(transcript)|ensembl:ENST00000420949(transcript)|ensembl:ENST00000424446(transcript)|ensembl:ENST00000426299(transcript)|ensembl:ENST00000429597(transcript)|ensembl:ENST00000449113(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0016604"(nuclear body)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0046872"(metal ion binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:1904290"(negative regulation of mitotic DNA damage checkpoint)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR017923|interpro:IPR035441|interpro:IPR036855|mint:Q96QC0|go:"GO:0000785"(chromatin) - function:"Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2)"|comment:mint comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:j6OmjKnEQkpMSoN3ok/kKPJMODM9606 rogid:ZWueXxqNFYPT0WhbfYdR3d2H2G89606 rigid:kBc1NUlSoDsbe7yRuX0UGxl8f7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86Y97 uniprotkb:O43290 intact:EBI-7960569|uniprotkb:Q8WZ10|uniprotkb:Q9BRZ6|intact:MINT-4776457|ensembl:ENSP00000255613 intact:EBI-607761|ensembl:ENSP00000310448|uniprotkb:A6NDN1|uniprotkb:Q53GB5 psi-mi:kmt5c_human(display_long)|uniprotkb:[histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:[histone H4]-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:PP7130(orf name)|uniprotkb:KMT5C(gene name)|psi-mi:KMT5C(display_short)|uniprotkb:Lysine N-methyltransferase 5C(gene name synonym)|uniprotkb:Lysine-specific methyltransferase 5C(gene name synonym)|uniprotkb:SUV420H2(gene name synonym)|uniprotkb:Suppressor of variegation 4-20 homolog 2(gene name synonym) psi-mi:snut1_human(display_long)|uniprotkb:U4/U6.U5 tri-snRNP-associated 110 kDa protein(gene name synonym)|uniprotkb:SART1(gene name)|psi-mi:SART1(display_short)|uniprotkb:SNU66 homolog(gene name synonym)|uniprotkb:Squamous cell carcinoma antigen recognized by T-cells 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485635|imex:IM-26985-445 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011525717.1|refseq:NP_116090.2|refseq:XP_005259395.1|refseq:XP_006723505.1|ensembl:ENSG00000133247(gene)|ensembl:ENST00000255613(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006281"(DNA repair)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0034772"(histone H4-K20 dimethylation)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0042393"(histone binding)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0046872"(metal ion binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001214(SET)|interpro:IPR025790|interpro:IPR039977|interpro:IPR041938|interpro:IPR044425|mint:Q86Y97|rcsb pdb:3RQ4|reactome:R-HSA-3214841 ensembl:ENSG00000175467(gene)|ensembl:ENST00000312397(transcript)|go:"GO:0000387"(spliceosomal snRNP assembly)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000481"(maturation of 5S rRNA)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0045585"(positive regulation of cytotoxic T cell differentiation)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR005011(SART-1 protein)|mint:O43290|rcsb pdb:4PYU|rcsb pdb:5O9Z|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|reactome:R-HSA-72163|refseq:NP_005137.1|dip:DIP-33360N - function:"Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2)"|comment:mint comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:j6OmjKnEQkpMSoN3ok/kKPJMODM9606 rogid:egvWHy7UXW+MkGtGEW984yvRU9k9606 rigid:kBc1NUlSoDsbe7yRuX0UGxl8f7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86Y97 uniprotkb:O14647 intact:EBI-7960569|uniprotkb:Q8WZ10|uniprotkb:Q9BRZ6|intact:MINT-4776457|ensembl:ENSP00000255613 intact:EBI-1210503|uniprotkb:C6G482|uniprotkb:Q96IP5|ensembl:ENSP00000377747 psi-mi:kmt5c_human(display_long)|uniprotkb:[histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:[histone H4]-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:PP7130(orf name)|uniprotkb:KMT5C(gene name)|psi-mi:KMT5C(display_short)|uniprotkb:Lysine N-methyltransferase 5C(gene name synonym)|uniprotkb:Lysine-specific methyltransferase 5C(gene name synonym)|uniprotkb:SUV420H2(gene name synonym)|uniprotkb:Suppressor of variegation 4-20 homolog 2(gene name synonym) psi-mi:chd2_human(display_long)|uniprotkb:CHD2(gene name)|psi-mi:CHD2(display_short)|uniprotkb:ATP-dependent helicase CHD2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485635|imex:IM-26985-445 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011525717.1|refseq:NP_116090.2|refseq:XP_005259395.1|refseq:XP_006723505.1|ensembl:ENSG00000133247(gene)|ensembl:ENST00000255613(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006281"(DNA repair)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0034772"(histone H4-K20 dimethylation)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0042393"(histone binding)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0046872"(metal ion binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001214(SET)|interpro:IPR025790|interpro:IPR039977|interpro:IPR041938|interpro:IPR044425|mint:Q86Y97|rcsb pdb:3RQ4|reactome:R-HSA-3214841 refseq:NP_001262.3|refseq:NP_001036037.1|interpro:IPR023780|interpro:IPR025260|interpro:IPR027417|interpro:IPR038718|interpro:IPR040793|mint:O14647|interpro:IPR023779|ensembl:ENSG00000173575(gene)|ensembl:ENST00000394196(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007517"(muscle organ development)|go:"GO:0042393"(histone binding)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0070615"|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000330(SNF2-related)|interpro:IPR000953(Chromo domain)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016197(Chromo domain-like) - function:"Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2)"|comment:mint comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:j6OmjKnEQkpMSoN3ok/kKPJMODM9606 rogid:Vibq3UdOTD39yhVlCgkyhzxw1Zw9606 rigid:kBc1NUlSoDsbe7yRuX0UGxl8f7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86Y97 uniprotkb:Q9UK58 intact:EBI-7960569|uniprotkb:Q8WZ10|uniprotkb:Q9BRZ6|intact:MINT-4776457|ensembl:ENSP00000255613 intact:EBI-2836773|uniprotkb:B3KMY3|uniprotkb:Q96QT0|uniprotkb:Q9NZF3|uniprotkb:Q8NI48|uniprotkb:Q6NVY9|uniprotkb:Q6UWS7|intact:EBI-11158173|uniprotkb:C9JPL0|ensembl:ENSP00000295926 psi-mi:kmt5c_human(display_long)|uniprotkb:[histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:[histone H4]-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:PP7130(orf name)|uniprotkb:KMT5C(gene name)|psi-mi:KMT5C(display_short)|uniprotkb:Lysine N-methyltransferase 5C(gene name synonym)|uniprotkb:Lysine-specific methyltransferase 5C(gene name synonym)|uniprotkb:SUV420H2(gene name synonym)|uniprotkb:Suppressor of variegation 4-20 homolog 2(gene name synonym) psi-mi:ccnl1_human(display_long)|uniprotkb:CCNL1(gene name)|psi-mi:CCNL1(display_short)|uniprotkb:BM-001(orf name)|uniprotkb:UNQ530/PRO1073(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485635|imex:IM-26985-445 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011525717.1|refseq:NP_116090.2|refseq:XP_005259395.1|refseq:XP_006723505.1|ensembl:ENSG00000133247(gene)|ensembl:ENST00000255613(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006281"(DNA repair)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0034772"(histone H4-K20 dimethylation)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0042393"(histone binding)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0046872"(metal ion binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001214(SET)|interpro:IPR025790|interpro:IPR039977|interpro:IPR041938|interpro:IPR044425|mint:Q86Y97|rcsb pdb:3RQ4|reactome:R-HSA-3214841 refseq:NP_064703.1|refseq:NP_001295114.1|ensembl:ENSG00000163660(gene)|ensembl:ENST00000295926(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006396"(RNA processing)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0016607"(nuclear speck)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR015431(Cyclin L, metazoan)|interpro:IPR036915|interpro:IPR043198|mint:Q9UK58|refseq:XP_016862381.1|refseq:XP_016862382.1|refseq:XP_016862383.1|refseq:XP_016862384.1|refseq:XP_016862385.1 - function:"Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2)"|comment:mint comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:j6OmjKnEQkpMSoN3ok/kKPJMODM9606 rogid:FMdaN/nrdmMEbSN1KKt0fZjubAc9606 rigid:kBc1NUlSoDsbe7yRuX0UGxl8f7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86Y97 uniprotkb:P05412 intact:EBI-7960569|uniprotkb:Q8WZ10|uniprotkb:Q9BRZ6|intact:MINT-4776457|ensembl:ENSP00000255613 intact:EBI-852823|uniprotkb:Q96G93|uniprotkb:Q6FHM7|ensembl:ENSP00000360266|ensembl:ENSP00000503132 psi-mi:kmt5c_human(display_long)|uniprotkb:[histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:[histone H4]-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:PP7130(orf name)|uniprotkb:KMT5C(gene name)|psi-mi:KMT5C(display_short)|uniprotkb:Lysine N-methyltransferase 5C(gene name synonym)|uniprotkb:Lysine-specific methyltransferase 5C(gene name synonym)|uniprotkb:SUV420H2(gene name synonym)|uniprotkb:Suppressor of variegation 4-20 homolog 2(gene name synonym) psi-mi:jun_human(display_long)|uniprotkb:JUN(gene name)|psi-mi:JUN(display_short)|uniprotkb:Activator protein 1(gene name synonym)|uniprotkb:Proto-oncogene c-Jun(gene name synonym)|uniprotkb:V-jun avian sarcoma virus 17 oncogene homolog(gene name synonym)|uniprotkb:p39(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485635|imex:IM-26985-445 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011525717.1|refseq:NP_116090.2|refseq:XP_005259395.1|refseq:XP_006723505.1|ensembl:ENSG00000133247(gene)|ensembl:ENST00000255613(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006281"(DNA repair)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0034772"(histone H4-K20 dimethylation)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0042393"(histone binding)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0046872"(metal ion binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001214(SET)|interpro:IPR025790|interpro:IPR039977|interpro:IPR041938|interpro:IPR044425|mint:Q86Y97|rcsb pdb:3RQ4|reactome:R-HSA-3214841 refseq:NP_002219.1|ensembl:ENSP00000360266|ensembl:ENSP00000503132|dip:DIP-5961N|ensembl:ENSG00000177606(gene)|ensembl:ENST00000371222(transcript)|ensembl:ENST00000678696(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001525"(angiogenesis)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007568"(aging)|go:"GO:0007612"(learning)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009314"(response to radiation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034097"(response to cytokine)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0035976"(transcription factor AP-1 complex)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0043922"(negative regulation by host of viral transcription)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045657"(positive regulation of monocyte differentiation)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051365"(cellular response to potassium ion starvation)|go:"GO:0051591"(response to cAMP)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051899"(membrane depolarization)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071837"(HMG box domain binding)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:2000144"(positive regulation of DNA-templated transcription, initiation)|interpro:IPR002112(Transcription factor Jun)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR005643(Jun-like transcription factor)|interpro:IPR008917(Eukaryotic transcription factor, Skn-1-like, DNA-binding)|interpro:IPR015558(c-Jun Transcription Factor)|mint:P05412|rcsb pdb:1A02|rcsb pdb:1FOS|rcsb pdb:1JNM|rcsb pdb:1JUN|rcsb pdb:1S9K|rcsb pdb:1T2K|rcsb pdb:5FV8|rcsb pdb:5T01|rcsb pdb:6Y3V|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2871796|reactome:R-HSA-450341|reactome:R-HSA-5617472|reactome:R-HSA-5687128|reactome:R-HSA-6796648|reactome:R-HSA-8862803|reactome:R-HSA-8943724|reactome:R-HSA-9018519|reactome:R-HSA-9673324 - function:"Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2)"|comment:mint comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:j6OmjKnEQkpMSoN3ok/kKPJMODM9606 rogid:zAVYwedHKKdvPPGttBP4XZkbCXA9606 rigid:kBc1NUlSoDsbe7yRuX0UGxl8f7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86Y97 uniprotkb:O00257 intact:EBI-7960569|uniprotkb:Q8WZ10|uniprotkb:Q9BRZ6|intact:MINT-4776457|ensembl:ENSP00000255613 intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397 psi-mi:kmt5c_human(display_long)|uniprotkb:[histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:[histone H4]-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:PP7130(orf name)|uniprotkb:KMT5C(gene name)|psi-mi:KMT5C(display_short)|uniprotkb:Lysine N-methyltransferase 5C(gene name synonym)|uniprotkb:Lysine-specific methyltransferase 5C(gene name synonym)|uniprotkb:SUV420H2(gene name synonym)|uniprotkb:Suppressor of variegation 4-20 homolog 2(gene name synonym) psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485635|imex:IM-26985-445 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011525717.1|refseq:NP_116090.2|refseq:XP_005259395.1|refseq:XP_006723505.1|ensembl:ENSG00000133247(gene)|ensembl:ENST00000255613(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006281"(DNA repair)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0034772"(histone H4-K20 dimethylation)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0042393"(histone binding)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0046872"(metal ion binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001214(SET)|interpro:IPR025790|interpro:IPR039977|interpro:IPR041938|interpro:IPR044425|mint:Q86Y97|rcsb pdb:3RQ4|reactome:R-HSA-3214841 refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724 - function:"Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2)"|comment:mint comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:j6OmjKnEQkpMSoN3ok/kKPJMODM9606 rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606 rigid:kBc1NUlSoDsbe7yRuX0UGxl8f7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86Y97 uniprotkb:Q8WWM7 intact:EBI-7960569|uniprotkb:Q8WZ10|uniprotkb:Q9BRZ6|intact:MINT-4776457|ensembl:ENSP00000255613 intact:EBI-948363|ensembl:ENSP00000338718|uniprotkb:O95135|uniprotkb:Q6NVJ8|uniprotkb:Q6PJW6|uniprotkb:Q8IU61|uniprotkb:Q8IU95|uniprotkb:Q8WWM3|uniprotkb:Q8WWM4|uniprotkb:Q8WWM5|uniprotkb:Q8WWM6|uniprotkb:Q99703|uniprotkb:B9EGM2|uniprotkb:E9PAR9|uniprotkb:A8K1R6|uniprotkb:Q63ZY4 psi-mi:kmt5c_human(display_long)|uniprotkb:[histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:[histone H4]-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:PP7130(orf name)|uniprotkb:KMT5C(gene name)|psi-mi:KMT5C(display_short)|uniprotkb:Lysine N-methyltransferase 5C(gene name synonym)|uniprotkb:Lysine-specific methyltransferase 5C(gene name synonym)|uniprotkb:SUV420H2(gene name synonym)|uniprotkb:Suppressor of variegation 4-20 homolog 2(gene name synonym) psi-mi:atx2l_human(display_long)|uniprotkb:Ataxin-2 domain protein(gene name synonym)|uniprotkb:Ataxin-2-related protein(gene name synonym)|uniprotkb:ATXN2L(gene name)|psi-mi:ATXN2L(display_short)|uniprotkb:A2D(gene name synonym)|uniprotkb:A2LG(gene name synonym)|uniprotkb:A2LP(gene name synonym)|uniprotkb:A2RP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485635|imex:IM-26985-445 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011525717.1|refseq:NP_116090.2|refseq:XP_005259395.1|refseq:XP_006723505.1|ensembl:ENSG00000133247(gene)|ensembl:ENST00000255613(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006281"(DNA repair)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0034772"(histone H4-K20 dimethylation)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0042393"(histone binding)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0046872"(metal ion binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001214(SET)|interpro:IPR025790|interpro:IPR039977|interpro:IPR041938|interpro:IPR044425|mint:Q86Y97|rcsb pdb:3RQ4|reactome:R-HSA-3214841 ensembl:ENSG00000168488(gene)|ensembl:ENST00000336783(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045296"(cadherin binding)|interpro:IPR009604(Ataxin-2, N-terminal)|interpro:IPR009818(Ataxin-2, C-terminal)|interpro:IPR025852|mint:Q8WWM7|refseq:NP_009176.2|refseq:NP_663760.1|refseq:NP_680780.1|refseq:NP_680781.1|refseq:XP_005255123.1|refseq:NP_059867.3|refseq:NP_680782.1 - function:"Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2)"|comment:mint comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:j6OmjKnEQkpMSoN3ok/kKPJMODM9606 rogid:t7lrS10IM/5pt+rrbqBRowZ6b+09606 rigid:kBc1NUlSoDsbe7yRuX0UGxl8f7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86Y97 uniprotkb:O94842 intact:EBI-7960569|uniprotkb:Q8WZ10|uniprotkb:Q9BRZ6|intact:MINT-4776457|ensembl:ENSP00000255613 intact:EBI-948613|ensembl:ENSP00000393080|ensembl:ENSP00000477868|intact:EBI-10965337|uniprotkb:B4DPY8|uniprotkb:E7EV69|uniprotkb:B4DSM0 psi-mi:kmt5c_human(display_long)|uniprotkb:[histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:[histone H4]-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:PP7130(orf name)|uniprotkb:KMT5C(gene name)|psi-mi:KMT5C(display_short)|uniprotkb:Lysine N-methyltransferase 5C(gene name synonym)|uniprotkb:Lysine-specific methyltransferase 5C(gene name synonym)|uniprotkb:SUV420H2(gene name synonym)|uniprotkb:Suppressor of variegation 4-20 homolog 2(gene name synonym) psi-mi:tox4_human(display_long)|uniprotkb:Epidermal Langerhans cell protein LCP1(gene name synonym)|uniprotkb:TOX4(gene name)|psi-mi:TOX4(display_short)|uniprotkb:KIAA0737(gene name synonym)|uniprotkb:C14orf92(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485635|imex:IM-26985-445 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011525717.1|refseq:NP_116090.2|refseq:XP_005259395.1|refseq:XP_006723505.1|ensembl:ENSG00000133247(gene)|ensembl:ENST00000255613(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006281"(DNA repair)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0034772"(histone H4-K20 dimethylation)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0042393"(histone binding)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0046872"(metal ion binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001214(SET)|interpro:IPR025790|interpro:IPR039977|interpro:IPR041938|interpro:IPR044425|mint:Q86Y97|rcsb pdb:3RQ4|reactome:R-HSA-3214841 ensembl:ENSG00000092203(gene)|ensembl:ENST00000448790(transcript)|ensembl:ENST00000613569(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|interpro:IPR037985|mint:O94842|refseq:NP_055643.1|refseq:NP_001290452.1 - function:"Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2)"|comment:mint comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:j6OmjKnEQkpMSoN3ok/kKPJMODM9606 rogid:tiW0mcDNOr9TsvNLVZ+f36eiNpY9606 rigid:kBc1NUlSoDsbe7yRuX0UGxl8f7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86Y97 uniprotkb:Q9H7H0 intact:EBI-7960569|uniprotkb:Q8WZ10|uniprotkb:Q9BRZ6|intact:MINT-4776457|ensembl:ENSP00000255613 intact:EBI-749353|intact:EBI-948255|uniprotkb:Q9BSH1|uniprotkb:Q9BZH2|uniprotkb:Q9BZH3|ensembl:ENSP00000343041 psi-mi:kmt5c_human(display_long)|uniprotkb:[histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:[histone H4]-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:PP7130(orf name)|uniprotkb:KMT5C(gene name)|psi-mi:KMT5C(display_short)|uniprotkb:Lysine N-methyltransferase 5C(gene name synonym)|uniprotkb:Lysine-specific methyltransferase 5C(gene name synonym)|uniprotkb:SUV420H2(gene name synonym)|uniprotkb:Suppressor of variegation 4-20 homolog 2(gene name synonym) psi-mi:met17_human(display_long)|uniprotkb:METT11D1(gene name synonym)|uniprotkb:Protein RSM22 homolog, mitochondrial(gene name synonym)|uniprotkb:METTL17(gene name)|psi-mi:METTL17(display_short)|uniprotkb:Methyltransferase 11 domain-containing protein 1(gene name synonym)|uniprotkb:False p73 target gene protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485635|imex:IM-26985-445 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011525717.1|refseq:NP_116090.2|refseq:XP_005259395.1|refseq:XP_006723505.1|ensembl:ENSG00000133247(gene)|ensembl:ENST00000255613(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006281"(DNA repair)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0034772"(histone H4-K20 dimethylation)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0042393"(histone binding)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0046872"(metal ion binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001214(SET)|interpro:IPR025790|interpro:IPR039977|interpro:IPR041938|interpro:IPR044425|mint:Q86Y97|rcsb pdb:3RQ4|reactome:R-HSA-3214841 refseq:NP_001025162.1|refseq:NP_073571.1|ensembl:ENSG00000165792(gene)|ensembl:ENST00000339374(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006412"(translation)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0032259"(methylation)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR015324(Ribosomal protein Rsm22, bacterial-type)|interpro:IPR029063|mint:Q9H7H0 - function:"Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2)"|comment:mint comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:j6OmjKnEQkpMSoN3ok/kKPJMODM9606 rogid:RAj8jOqwthd7a0Xzi5FWhVKc8OI9606 rigid:kBc1NUlSoDsbe7yRuX0UGxl8f7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86Y97 uniprotkb:Q13523 intact:EBI-7960569|uniprotkb:Q8WZ10|uniprotkb:Q9BRZ6|intact:MINT-4776457|ensembl:ENSP00000255613 intact:EBI-395940|uniprotkb:Q8TDP2|uniprotkb:Q96QT7|uniprotkb:Q9UEE6|uniprotkb:Q5TAY8|uniprotkb:A8K5C9|uniprotkb:Q5D0F6|uniprotkb:Q8IVC3|intact:EBI-1058380|ensembl:ENSP00000337194|ensembl:ENSP00000433547 psi-mi:kmt5c_human(display_long)|uniprotkb:[histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:[histone H4]-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:PP7130(orf name)|uniprotkb:KMT5C(gene name)|psi-mi:KMT5C(display_short)|uniprotkb:Lysine N-methyltransferase 5C(gene name synonym)|uniprotkb:Lysine-specific methyltransferase 5C(gene name synonym)|uniprotkb:SUV420H2(gene name synonym)|uniprotkb:Suppressor of variegation 4-20 homolog 2(gene name synonym) psi-mi:prp4b_human(display_long)|uniprotkb:PRPF4B(gene name)|psi-mi:PRPF4B(display_short)|uniprotkb:KIAA0536(gene name synonym)|uniprotkb:PRP4(gene name synonym)|uniprotkb:PRP4H(gene name synonym)|uniprotkb:PRP4K(gene name synonym)|uniprotkb:PRP4 pre-mRNA-processing factor 4 homolog(gene name synonym)|uniprotkb:PRP4 kinase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485635|imex:IM-26985-445 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011525717.1|refseq:NP_116090.2|refseq:XP_005259395.1|refseq:XP_006723505.1|ensembl:ENSG00000133247(gene)|ensembl:ENST00000255613(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006281"(DNA repair)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0034772"(histone H4-K20 dimethylation)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0042393"(histone binding)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0046872"(metal ion binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001214(SET)|interpro:IPR025790|interpro:IPR039977|interpro:IPR041938|interpro:IPR044425|mint:Q86Y97|rcsb pdb:3RQ4|reactome:R-HSA-3214841 refseq:NP_003904.3|ensembl:ENSG00000112739(gene)|ensembl:ENST00000337659(transcript)|ensembl:ENST00000480058(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR044092|mint:Q13523|rcsb pdb:4IAN|rcsb pdb:4IFC|rcsb pdb:4IIR|rcsb pdb:4IJP|rcsb pdb:6CNH|rcsb pdb:6PJJ|rcsb pdb:6PK6|rcsb pdb:6QX9|refseq:XP_016866899.1|refseq:XP_016866900.1|refseq:XP_016866901.1|refseq:XP_016866902.1|refseq:XP_016866903.1|refseq:XP_016866904.1|refseq:XP_016866905.1|refseq:XP_016866906.1|refseq:XP_016866907.1|refseq:XP_016866908.1|refseq:XP_016866909.1|refseq:XP_016866910.1|refseq:XP_016866911.1|refseq:XP_016866912.1|refseq:XP_016866913.1|refseq:XP_016866914.1|refseq:XP_016866915.1|refseq:XP_016866916.1|refseq:XP_016866917.1|refseq:XP_016866918.1|refseq:XP_016866919.1|refseq:XP_016866920.1 - function:"Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2)"|comment:mint comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:j6OmjKnEQkpMSoN3ok/kKPJMODM9606 rogid:ZklPbRvRbbVRJYqV3JkS2jG3EIc9606 rigid:kBc1NUlSoDsbe7yRuX0UGxl8f7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86Y97 uniprotkb:P11387 intact:EBI-7960569|uniprotkb:Q8WZ10|uniprotkb:Q9BRZ6|intact:MINT-4776457|ensembl:ENSP00000255613 intact:EBI-876302|ensembl:ENSP00000354522|uniprotkb:Q15610|uniprotkb:Q5TFY3|uniprotkb:Q9UJN0|uniprotkb:O43256|uniprotkb:Q12855|uniprotkb:Q12856|uniprotkb:A8KA78|uniprotkb:E1P5W3 psi-mi:kmt5c_human(display_long)|uniprotkb:[histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:[histone H4]-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:PP7130(orf name)|uniprotkb:KMT5C(gene name)|psi-mi:KMT5C(display_short)|uniprotkb:Lysine N-methyltransferase 5C(gene name synonym)|uniprotkb:Lysine-specific methyltransferase 5C(gene name synonym)|uniprotkb:SUV420H2(gene name synonym)|uniprotkb:Suppressor of variegation 4-20 homolog 2(gene name synonym) psi-mi:top1_human(display_long)|uniprotkb:DNA topoisomerase I(gene name synonym)|uniprotkb:TOP1(gene name)|psi-mi:TOP1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485635|imex:IM-26985-445 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011525717.1|refseq:NP_116090.2|refseq:XP_005259395.1|refseq:XP_006723505.1|ensembl:ENSG00000133247(gene)|ensembl:ENST00000255613(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006281"(DNA repair)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0034772"(histone H4-K20 dimethylation)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0042393"(histone binding)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0046872"(metal ion binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001214(SET)|interpro:IPR025790|interpro:IPR039977|interpro:IPR041938|interpro:IPR044425|mint:Q86Y97|rcsb pdb:3RQ4|reactome:R-HSA-3214841 ensembl:ENSG00000198900(gene)|ensembl:ENST00000361337(transcript)|go:"GO:0000932"(P-body)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006265"(DNA topological change)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007623"(circadian rhythm)|go:"GO:0012501"(programmed cell death)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032922"(circadian regulation of gene expression)|refseq:NP_003277.1|dip:DIP-36356N|go:"GO:0032993"(protein-DNA complex)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042493"|go:"GO:0043204"(perikaryon)|go:"GO:0097100"(supercoiled DNA binding)|interpro:IPR001631(DNA topoisomerase I, C-terminal)|interpro:IPR008336(DNA topoisomerase I, DNA binding, eukaryotic-type)|interpro:IPR011010(DNA breaking-rejoining enzyme, catalytic core)|interpro:IPR013030(DNA topoisomerase I, DNA binding, mixed alpha/beta motif, eukaryotic-type)|interpro:IPR013034(DNA topoisomerase I, DNA binding, alpha helical motif, eukaryotic-type)|interpro:IPR013499(DNA topoisomerase I, C-terminal, eukaryotic-type)|interpro:IPR013500(DNA topoisomerase I, catalytic core, eukaryotic-type)|interpro:IPR014711(DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type)|interpro:IPR014727(DNA topoisomerase I, catalytic core, alpha/beta subdomain, eukaryotic-type)|interpro:IPR018521|interpro:IPR025834|interpro:IPR036202|mint:P11387|rcsb pdb:1A31|rcsb pdb:1A35|rcsb pdb:1A36|rcsb pdb:1EJ9|rcsb pdb:1K4S|rcsb pdb:1K4T|rcsb pdb:1LPQ|rcsb pdb:1NH3|rcsb pdb:1R49|rcsb pdb:1RR8|rcsb pdb:1RRJ|rcsb pdb:1SC7|rcsb pdb:1SEU|rcsb pdb:1T8I|rcsb pdb:1TL8|reactome:R-HSA-4615885 - function:"Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2)"|comment:mint comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:j6OmjKnEQkpMSoN3ok/kKPJMODM9606 rogid:kB+3PVybgNp2mtOmDa7x8sygFuU9606 rigid:kBc1NUlSoDsbe7yRuX0UGxl8f7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86Y97 uniprotkb:Q8TAV0 intact:EBI-7960569|uniprotkb:Q8WZ10|uniprotkb:Q9BRZ6|intact:MINT-4776457|ensembl:ENSP00000255613 intact:EBI-20865780|ensembl:ENSP00000363065|uniprotkb:B4DWT3|uniprotkb:O95565|uniprotkb:O95566|uniprotkb:Q8N7J5 psi-mi:kmt5c_human(display_long)|uniprotkb:[histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:[histone H4]-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:PP7130(orf name)|uniprotkb:KMT5C(gene name)|psi-mi:KMT5C(display_short)|uniprotkb:Lysine N-methyltransferase 5C(gene name synonym)|uniprotkb:Lysine-specific methyltransferase 5C(gene name synonym)|uniprotkb:SUV420H2(gene name synonym)|uniprotkb:Suppressor of variegation 4-20 homolog 2(gene name synonym) psi-mi:fa76a_human(display_long)|uniprotkb:FAM76A(gene name)|psi-mi:FAM76A(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485635|imex:IM-26985-445 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011525717.1|refseq:NP_116090.2|refseq:XP_005259395.1|refseq:XP_006723505.1|ensembl:ENSG00000133247(gene)|ensembl:ENST00000255613(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006281"(DNA repair)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0034772"(histone H4-K20 dimethylation)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0042393"(histone binding)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0046872"(metal ion binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001214(SET)|interpro:IPR025790|interpro:IPR039977|interpro:IPR041938|interpro:IPR044425|mint:Q86Y97|rcsb pdb:3RQ4|reactome:R-HSA-3214841 ensembl:ENST00000373954(transcript)|go:"GO:0005654"(nucleoplasm)|interpro:IPR029660|interpro:IPR032017|mint:Q8TAV0|ensembl:ENSG00000009780(gene)|refseq:NP_001137384.1|refseq:NP_001137385.1|refseq:NP_001137386.1|refseq:NP_001137387.1|refseq:NP_689873.1 - function:"Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2)"|comment:mint comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:j6OmjKnEQkpMSoN3ok/kKPJMODM9606 rogid:dl/BpWuBO1PpS3chuG29jL9J3JI9606 rigid:kBc1NUlSoDsbe7yRuX0UGxl8f7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86Y97 uniprotkb:Q6UXN9 intact:EBI-7960569|uniprotkb:Q8WZ10|uniprotkb:Q9BRZ6|intact:MINT-4776457|ensembl:ENSP00000255613 intact:EBI-1176082|uniprotkb:Q8TEB2|uniprotkb:A8K5R5|intact:EBI-2562464|ensembl:ENSP00000296490 psi-mi:kmt5c_human(display_long)|uniprotkb:[histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:[histone H4]-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:PP7130(orf name)|uniprotkb:KMT5C(gene name)|psi-mi:KMT5C(display_short)|uniprotkb:Lysine N-methyltransferase 5C(gene name synonym)|uniprotkb:Lysine-specific methyltransferase 5C(gene name synonym)|uniprotkb:SUV420H2(gene name synonym)|uniprotkb:Suppressor of variegation 4-20 homolog 2(gene name synonym) psi-mi:wdr82_human(display_long)|uniprotkb:Protein TMEM113(gene name synonym)|uniprotkb:TMEM113(gene name synonym)|uniprotkb:WDR82(gene name)|psi-mi:WDR82(display_short)|uniprotkb:Swd2(gene name synonym)|uniprotkb:WDR82A(gene name synonym)|uniprotkb:UNQ9342/PRO34047(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485635|imex:IM-26985-445 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011525717.1|refseq:NP_116090.2|refseq:XP_005259395.1|refseq:XP_006723505.1|ensembl:ENSG00000133247(gene)|ensembl:ENST00000255613(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006281"(DNA repair)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0034772"(histone H4-K20 dimethylation)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0042393"(histone binding)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0046872"(metal ion binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001214(SET)|interpro:IPR025790|interpro:IPR039977|interpro:IPR041938|interpro:IPR044425|mint:Q86Y97|rcsb pdb:3RQ4|reactome:R-HSA-3214841 refseq:NP_079498.2|ensembl:ENSG00000164091(gene)|ensembl:ENST00000296490(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005730"(nucleolus)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|interpro:IPR037867|mint:Q6UXN9 - function:"Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2)"|comment:mint comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:j6OmjKnEQkpMSoN3ok/kKPJMODM9606 rogid:0TyKYwpTLd22Cm+ihT1+n0oo12c9606 rigid:kBc1NUlSoDsbe7yRuX0UGxl8f7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86Y97 uniprotkb:Q7L2J0 intact:EBI-7960569|uniprotkb:Q8WZ10|uniprotkb:Q9BRZ6|intact:MINT-4776457|ensembl:ENSP00000255613 intact:EBI-2371983|uniprotkb:Q9NPD4|uniprotkb:B3KP86|uniprotkb:D6W5V7|ensembl:ENSP00000308546 psi-mi:kmt5c_human(display_long)|uniprotkb:[histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:[histone H4]-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:PP7130(orf name)|uniprotkb:KMT5C(gene name)|psi-mi:KMT5C(display_short)|uniprotkb:Lysine N-methyltransferase 5C(gene name synonym)|uniprotkb:Lysine-specific methyltransferase 5C(gene name synonym)|uniprotkb:SUV420H2(gene name synonym)|uniprotkb:Suppressor of variegation 4-20 homolog 2(gene name synonym) psi-mi:mepce_human(display_long)|uniprotkb:MEPCE(gene name)|psi-mi:MEPCE(display_short)|uniprotkb:BCDIN3(gene name synonym)|uniprotkb:Bicoid-interacting protein 3 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485635|imex:IM-26985-445 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011525717.1|refseq:NP_116090.2|refseq:XP_005259395.1|refseq:XP_006723505.1|ensembl:ENSG00000133247(gene)|ensembl:ENST00000255613(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006281"(DNA repair)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0034772"(histone H4-K20 dimethylation)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0042393"(histone binding)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0046872"(metal ion binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001214(SET)|interpro:IPR025790|interpro:IPR039977|interpro:IPR041938|interpro:IPR044425|mint:Q86Y97|rcsb pdb:3RQ4|reactome:R-HSA-3214841 refseq:XP_011514712.1|refseq:NP_001181919.1|refseq:NP_001181920.1|refseq:NP_001181921.1|refseq:NP_062552.2|ensembl:ENSG00000146834(gene)|ensembl:ENST00000310512(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001510"(RNA methylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0008171"(O-methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0016073"(snRNA metabolic process)|go:"GO:0017069"(snRNA binding)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0040031"(snRNA modification)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1905382"(positive regulation of snRNA transcription by RNA polymerase II)|go:"GO:1990276"(RNA 5'-methyltransferase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR010675(Bicoid-interacting 3)|interpro:IPR024160|interpro:IPR025714|interpro:IPR029063|interpro:IPR039772|mint:Q7L2J0|rcsb pdb:5UNA|rcsb pdb:6DCB|rcsb pdb:6DCC - function:"Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2)"|comment:mint comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:j6OmjKnEQkpMSoN3ok/kKPJMODM9606 rogid:VGhJoO3FD7nsJPVSBsKuKsPJzEM9606 rigid:kBc1NUlSoDsbe7yRuX0UGxl8f7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86Y97 uniprotkb:Q8TC44 intact:EBI-7960569|uniprotkb:Q8WZ10|uniprotkb:Q9BRZ6|intact:MINT-4776457|ensembl:ENSP00000255613 intact:EBI-1176274|ensembl:ENSP00000323302|uniprotkb:G3V1X0 psi-mi:kmt5c_human(display_long)|uniprotkb:[histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:[histone H4]-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:PP7130(orf name)|uniprotkb:KMT5C(gene name)|psi-mi:KMT5C(display_short)|uniprotkb:Lysine N-methyltransferase 5C(gene name synonym)|uniprotkb:Lysine-specific methyltransferase 5C(gene name synonym)|uniprotkb:SUV420H2(gene name synonym)|uniprotkb:Suppressor of variegation 4-20 homolog 2(gene name synonym) psi-mi:poc1b_human(display_long)|uniprotkb:POC1B(gene name)|psi-mi:POC1B(display_short)|uniprotkb:WDR51B(gene name synonym)|uniprotkb:WD repeat-containing protein 51B(gene name synonym)|uniprotkb:Pix1(gene name synonym)|uniprotkb:Proteome of centriole protein 1B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485635|imex:IM-26985-445 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011525717.1|refseq:NP_116090.2|refseq:XP_005259395.1|refseq:XP_006723505.1|ensembl:ENSG00000133247(gene)|ensembl:ENST00000255613(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006281"(DNA repair)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0034772"(histone H4-K20 dimethylation)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0042393"(histone binding)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0046872"(metal ion binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001214(SET)|interpro:IPR025790|interpro:IPR039977|interpro:IPR041938|interpro:IPR044425|mint:Q86Y97|rcsb pdb:3RQ4|reactome:R-HSA-3214841 refseq:NP_758440.1|ensembl:ENSG00000139323(gene)|ensembl:ENST00000313546(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|go:"GO:0008283"(cell population proliferation)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q8TC44|refseq:NP_001186706.1 - function:"Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2)"|comment:mint comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:j6OmjKnEQkpMSoN3ok/kKPJMODM9606 rogid:wLnp5gzUvx/+G6b2BJUDopNgpOc9606 rigid:kBc1NUlSoDsbe7yRuX0UGxl8f7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86Y97 uniprotkb:Q13185 intact:EBI-7960569|uniprotkb:Q8WZ10|uniprotkb:Q9BRZ6|intact:MINT-4776457|ensembl:ENSP00000255613 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 psi-mi:kmt5c_human(display_long)|uniprotkb:[histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:[histone H4]-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:PP7130(orf name)|uniprotkb:KMT5C(gene name)|psi-mi:KMT5C(display_short)|uniprotkb:Lysine N-methyltransferase 5C(gene name synonym)|uniprotkb:Lysine-specific methyltransferase 5C(gene name synonym)|uniprotkb:SUV420H2(gene name synonym)|uniprotkb:Suppressor of variegation 4-20 homolog 2(gene name synonym) psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485635|imex:IM-26985-445 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011525717.1|refseq:NP_116090.2|refseq:XP_005259395.1|refseq:XP_006723505.1|ensembl:ENSG00000133247(gene)|ensembl:ENST00000255613(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006281"(DNA repair)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0034772"(histone H4-K20 dimethylation)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0042393"(histone binding)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0046872"(metal ion binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001214(SET)|interpro:IPR025790|interpro:IPR039977|interpro:IPR041938|interpro:IPR044425|mint:Q86Y97|rcsb pdb:3RQ4|reactome:R-HSA-3214841 go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N - function:"Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2)"|comment:mint comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:j6OmjKnEQkpMSoN3ok/kKPJMODM9606 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rigid:kBc1NUlSoDsbe7yRuX0UGxl8f7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86Y97 uniprotkb:Q7Z417 intact:EBI-7960569|uniprotkb:Q8WZ10|uniprotkb:Q9BRZ6|intact:MINT-4776457|ensembl:ENSP00000255613 intact:EBI-1210753|intact:EBI-10172018|uniprotkb:A1L3A7|uniprotkb:Q9P2M5|uniprotkb:A1L3A6|ensembl:ENSP00000225388 psi-mi:kmt5c_human(display_long)|uniprotkb:[histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:[histone H4]-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:PP7130(orf name)|uniprotkb:KMT5C(gene name)|psi-mi:KMT5C(display_short)|uniprotkb:Lysine N-methyltransferase 5C(gene name synonym)|uniprotkb:Lysine-specific methyltransferase 5C(gene name synonym)|uniprotkb:SUV420H2(gene name synonym)|uniprotkb:Suppressor of variegation 4-20 homolog 2(gene name synonym) psi-mi:nufp2_human(display_long)|uniprotkb:NUFIP2(gene name)|psi-mi:NUFIP2(display_short)|uniprotkb:KIAA1321(gene name synonym)|uniprotkb:PIG1(orf name)|uniprotkb:FMRP-interacting protein 2(gene name synonym)|uniprotkb:82 kDa FMRP-interacting protein(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 1 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485635|imex:IM-26985-445 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011525717.1|refseq:NP_116090.2|refseq:XP_005259395.1|refseq:XP_006723505.1|ensembl:ENSG00000133247(gene)|ensembl:ENST00000255613(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006281"(DNA repair)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0034772"(histone H4-K20 dimethylation)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0042393"(histone binding)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0046872"(metal ion binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001214(SET)|interpro:IPR025790|interpro:IPR039977|interpro:IPR041938|interpro:IPR044425|mint:Q86Y97|rcsb pdb:3RQ4|reactome:R-HSA-3214841 refseq:NP_065823.1|dip:DIP-29023N|ensembl:ENSG00000108256(gene)|ensembl:ENST00000225388(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR032747|mint:Q7Z417 - function:"Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2)"|comment:mint comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:j6OmjKnEQkpMSoN3ok/kKPJMODM9606 rogid:zdbkRisveP+8g70umfbEPHTnAgk9606 rigid:kBc1NUlSoDsbe7yRuX0UGxl8f7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86Y97 uniprotkb:Q9UHR5 intact:EBI-7960569|uniprotkb:Q8WZ10|uniprotkb:Q9BRZ6|intact:MINT-4776457|ensembl:ENSP00000255613 intact:EBI-751683|uniprotkb:Q8N1R5|uniprotkb:Q8TDR8|uniprotkb:Q96D27|uniprotkb:B3KML7|ensembl:ENSP00000462116 psi-mi:kmt5c_human(display_long)|uniprotkb:[histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:[histone H4]-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:PP7130(orf name)|uniprotkb:KMT5C(gene name)|psi-mi:KMT5C(display_short)|uniprotkb:Lysine N-methyltransferase 5C(gene name synonym)|uniprotkb:Lysine-specific methyltransferase 5C(gene name synonym)|uniprotkb:SUV420H2(gene name synonym)|uniprotkb:Suppressor of variegation 4-20 homolog 2(gene name synonym) psi-mi:s30bp_human(display_long)|uniprotkb:Transcriptional regulator protein HCNGP(gene name synonym)|uniprotkb:SAP30BP(gene name)|psi-mi:SAP30BP(display_short)|uniprotkb:HTRG(gene name synonym)|uniprotkb:HCNGP(gene name synonym)|uniprotkb:HTRP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485635|imex:IM-26985-445 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011525717.1|refseq:NP_116090.2|refseq:XP_005259395.1|refseq:XP_006723505.1|ensembl:ENSG00000133247(gene)|ensembl:ENST00000255613(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006281"(DNA repair)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0034772"(histone H4-K20 dimethylation)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0042393"(histone binding)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0046872"(metal ion binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001214(SET)|interpro:IPR025790|interpro:IPR039977|interpro:IPR041938|interpro:IPR044425|mint:Q86Y97|rcsb pdb:3RQ4|reactome:R-HSA-3214841 refseq:NP_037392.1|refseq:NP_001288768.1|refseq:NP_001288784.1|ensembl:ENST00000355423|ensembl:ENSP00000347592|ensembl:ENSP00000462116|ensembl:ENSG00000161526(gene)|ensembl:ENST00000584667(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006915"(apoptotic process)|go:"GO:0009615"(response to virus)|go:"GO:0031065"(positive regulation of histone deacetylation)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0052472"(modulation by host of symbiont transcription)|interpro:IPR012479(HCNGP-like)|mint:Q9UHR5|reactome:R-HSA-427413 - function:"Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2)"|comment:mint comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:j6OmjKnEQkpMSoN3ok/kKPJMODM9606 rogid:Io+aePrfIfdTg8+V8A05c+qPpF89606 rigid:kBc1NUlSoDsbe7yRuX0UGxl8f7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86Y97 uniprotkb:P62750 intact:EBI-7960569|uniprotkb:Q8WZ10|uniprotkb:Q9BRZ6|intact:MINT-4776457|ensembl:ENSP00000255613 intact:EBI-353254|uniprotkb:P29316|uniprotkb:Q92774|uniprotkb:P39024|uniprotkb:B2R5B2|ensembl:ENSP00000389103 psi-mi:kmt5c_human(display_long)|uniprotkb:[histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:[histone H4]-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:PP7130(orf name)|uniprotkb:KMT5C(gene name)|psi-mi:KMT5C(display_short)|uniprotkb:Lysine N-methyltransferase 5C(gene name synonym)|uniprotkb:Lysine-specific methyltransferase 5C(gene name synonym)|uniprotkb:SUV420H2(gene name synonym)|uniprotkb:Suppressor of variegation 4-20 homolog 2(gene name synonym) psi-mi:rl23a_human(display_long)|uniprotkb:RPL23A(gene name)|psi-mi:RPL23A(display_short)|uniprotkb:Large ribosomal subunit protein uL23(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485635|imex:IM-26985-445 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011525717.1|refseq:NP_116090.2|refseq:XP_005259395.1|refseq:XP_006723505.1|ensembl:ENSG00000133247(gene)|ensembl:ENST00000255613(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006281"(DNA repair)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0034772"(histone H4-K20 dimethylation)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0042393"(histone binding)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0046872"(metal ion binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001214(SET)|interpro:IPR025790|interpro:IPR039977|interpro:IPR041938|interpro:IPR044425|mint:Q86Y97|rcsb pdb:3RQ4|reactome:R-HSA-3214841 reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|refseq:NP_000975.2|ensembl:ENSG00000198242(gene)|ensembl:ENST00000422514(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904841"(TORC2 complex binding)|interpro:IPR001014(Ribosomal protein L23, conserved site)|interpro:IPR005633(Ribosomal protein L23/L25, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR013025(Ribosomal protein L25/L23)|interpro:IPR019985|mint:P62750|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS - function:"Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2)"|comment:mint comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:j6OmjKnEQkpMSoN3ok/kKPJMODM9606 rogid:lA1ubRFO9/Tl54Z1dKUzoCKvpAo9606 rigid:kBc1NUlSoDsbe7yRuX0UGxl8f7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86Y97 uniprotkb:Q5HYJ3 intact:EBI-7960569|uniprotkb:Q8WZ10|uniprotkb:Q9BRZ6|intact:MINT-4776457|ensembl:ENSP00000255613 intact:EBI-751192|uniprotkb:Q6PIU3|uniprotkb:Q8TC53|uniprotkb:B2R9C2|ensembl:ENSP00000351631 psi-mi:kmt5c_human(display_long)|uniprotkb:[histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:[histone H4]-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:PP7130(orf name)|uniprotkb:KMT5C(gene name)|psi-mi:KMT5C(display_short)|uniprotkb:Lysine N-methyltransferase 5C(gene name synonym)|uniprotkb:Lysine-specific methyltransferase 5C(gene name synonym)|uniprotkb:SUV420H2(gene name synonym)|uniprotkb:Suppressor of variegation 4-20 homolog 2(gene name synonym) psi-mi:fa76b_human(display_long)|uniprotkb:FAM76B(gene name)|psi-mi:FAM76B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485635|imex:IM-26985-445 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011525717.1|refseq:NP_116090.2|refseq:XP_005259395.1|refseq:XP_006723505.1|ensembl:ENSG00000133247(gene)|ensembl:ENST00000255613(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006281"(DNA repair)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0034772"(histone H4-K20 dimethylation)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0042393"(histone binding)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0046872"(metal ion binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001214(SET)|interpro:IPR025790|interpro:IPR039977|interpro:IPR041938|interpro:IPR044425|mint:Q86Y97|rcsb pdb:3RQ4|reactome:R-HSA-3214841 refseq:NP_653265.3|ensembl:ENSG00000077458(gene)|ensembl:ENST00000358780(transcript)|go:"GO:0016607"(nuclear speck)|interpro:IPR029661|interpro:IPR032017|mint:Q5HYJ3 - function:"Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2)"|comment:mint comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:j6OmjKnEQkpMSoN3ok/kKPJMODM9606 rogid:FWmHMXjKuPdNvpa793hQ1F+Tb909606 rigid:kBc1NUlSoDsbe7yRuX0UGxl8f7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86Y97 uniprotkb:Q15233 intact:EBI-7960569|uniprotkb:Q8WZ10|uniprotkb:Q9BRZ6|intact:MINT-4776457|ensembl:ENSP00000255613 intact:EBI-350527|ensembl:ENSP00000503233|uniprotkb:O00201|uniprotkb:P30807|uniprotkb:Q12786|uniprotkb:Q9BQC5|ensembl:ENSP00000276079|ensembl:ENSP00000362947|ensembl:ENSP00000406673|ensembl:ENSP00000410299|ensembl:ENSP00000415777|ensembl:ENSP00000503031|ensembl:ENSP00000504314|ensembl:ENSP00000504351|uniprotkb:D3DVV4|uniprotkb:B7Z4C2|uniprotkb:F5GYZ3 psi-mi:kmt5c_human(display_long)|uniprotkb:[histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:[histone H4]-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:PP7130(orf name)|uniprotkb:KMT5C(gene name)|psi-mi:KMT5C(display_short)|uniprotkb:Lysine N-methyltransferase 5C(gene name synonym)|uniprotkb:Lysine-specific methyltransferase 5C(gene name synonym)|uniprotkb:SUV420H2(gene name synonym)|uniprotkb:Suppressor of variegation 4-20 homolog 2(gene name synonym) psi-mi:nono_human(display_long)|uniprotkb:NONO(gene name)|psi-mi:NONO(display_short)|uniprotkb:NRB54(gene name synonym)|uniprotkb:54 kDa nuclear RNA- and DNA-binding protein(gene name synonym)|uniprotkb:"p54(nrb)"(gene name synonym)|uniprotkb:55 kDa nuclear protein(gene name synonym)|uniprotkb:NMT55(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 52 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485635|imex:IM-26985-445 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011525717.1|refseq:NP_116090.2|refseq:XP_005259395.1|refseq:XP_006723505.1|ensembl:ENSG00000133247(gene)|ensembl:ENST00000255613(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006281"(DNA repair)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0034772"(histone H4-K20 dimethylation)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0042393"(histone binding)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0046872"(metal ion binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001214(SET)|interpro:IPR025790|interpro:IPR039977|interpro:IPR041938|interpro:IPR044425|mint:Q86Y97|rcsb pdb:3RQ4|reactome:R-HSA-3214841 refseq:NP_001138880.1|refseq:NP_001138881.1|refseq:NP_001138882.1|refseq:NP_031389.3|ensembl:ENSG00000147140(gene)|ensembl:ENST00000276079(transcript)|ensembl:ENST00000373841(transcript)|ensembl:ENST00000420903(transcript)|ensembl:ENST00000450092(transcript)|ensembl:ENST00000454976(transcript)|ensembl:ENST00000677274(transcript)|ensembl:ENST00000677446(transcript)|ensembl:ENST00000677612(transcript)|ensembl:ENST00000678231(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0042382"(paraspeckles)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034552|interpro:IPR035979|mint:Q15233|rcsb pdb:3SDE|rcsb pdb:5IFM|rcsb pdb:6WMZ|rcsb pdb:7LRQ|dip:DIP-29951N - function:"Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2)"|comment:mint comment:"author score: 29" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:j6OmjKnEQkpMSoN3ok/kKPJMODM9606 rogid:5W3ooO4h0qh3GKO+WjDrLBhihHA9606 rigid:kBc1NUlSoDsbe7yRuX0UGxl8f7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86Y97 uniprotkb:P22528 intact:EBI-7960569|uniprotkb:Q8WZ10|uniprotkb:Q9BRZ6|intact:MINT-4776457|ensembl:ENSP00000255613 intact:EBI-1058892|ensembl:ENSP00000306461|uniprotkb:B2R5H7|uniprotkb:P22529|uniprotkb:P22530|uniprotkb:Q5T524 psi-mi:kmt5c_human(display_long)|uniprotkb:[histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:[histone H4]-lysine20 N-methyltransferase KMT5B(gene name synonym)|uniprotkb:PP7130(orf name)|uniprotkb:KMT5C(gene name)|psi-mi:KMT5C(display_short)|uniprotkb:Lysine N-methyltransferase 5C(gene name synonym)|uniprotkb:Lysine-specific methyltransferase 5C(gene name synonym)|uniprotkb:SUV420H2(gene name synonym)|uniprotkb:Suppressor of variegation 4-20 homolog 2(gene name synonym) psi-mi:spr1b_human(display_long)|uniprotkb:SPRR1B(gene name)|psi-mi:SPRR1B(display_short)|uniprotkb:Small proline-rich protein IB(gene name synonym)|uniprotkb:14.9 kDa pancornulin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485635|imex:IM-26985-445 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011525717.1|refseq:NP_116090.2|refseq:XP_005259395.1|refseq:XP_006723505.1|ensembl:ENSG00000133247(gene)|ensembl:ENST00000255613(transcript)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0006281"(DNA repair)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0034772"(histone H4-K20 dimethylation)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:0042393"(histone binding)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0046872"(metal ion binding)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR001214(SET)|interpro:IPR025790|interpro:IPR039977|interpro:IPR041938|interpro:IPR044425|mint:Q86Y97|rcsb pdb:3RQ4|reactome:R-HSA-3214841 ensembl:ENSG00000169469(gene)|ensembl:ENST00000307098(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0031424"(keratinization)|interpro:IPR003302("Cornifin (SPRR)")|mint:P22528|reactome:R-HSA-6809371|refseq:NP_003116.2 - function:"Histone methyltransferase that specifically trimethylates 'Lys-20' of histone H4. H4 'Lys-20' trimethylation represents a specific tag for epigenetic transcriptional repression. Mainly functions in pericentric heterochromatin regions, thereby playing a central role in the establishment of constitutive heterochromatin in these regions. SUV420H1 is targeted to histone H3 via its interaction with RB1 family proteins (RB1, RBL1 and RBL2)"|comment:mint comment:"author score: 31" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:j6OmjKnEQkpMSoN3ok/kKPJMODM9606 rogid:WU0vu+DHdIJm0x40HdcpAdJgdgo9606 rigid:kBc1NUlSoDsbe7yRuX0UGxl8f7A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NUW8 uniprotkb:P51784 intact:EBI-2902553|ensembl:ENSP00000337353|ensembl:ENSP00000377099|uniprotkb:Q2HXX4|uniprotkb:Q96BK7|uniprotkb:Q9NZM7|uniprotkb:Q9NZM8|uniprotkb:Q86TV8 intact:EBI-306876|intact:EBI-1058416|uniprotkb:Q8IUG6|uniprotkb:Q9BWE1|uniprotkb:B2RTX1|ensembl:ENSP00000218348 psi-mi:tydp1_human(display_long)|uniprotkb:TDP1(gene name)|psi-mi:TDP1(display_short) psi-mi:ubp11_human(display_long)|uniprotkb:USP11(gene name)|psi-mi:USP11(display_short)|uniprotkb:UHX1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 11(gene name synonym)|uniprotkb:Deubiquitinating enzyme 11(gene name synonym)|uniprotkb:Ubiquitin thioesterase 11(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485749|imex:IM-26985-589 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000042088(gene)|ensembl:ENST00000335725(transcript)|ensembl:ENST00000393454(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0017005"(3'-tyrosyl-DNA phosphodiesterase activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR010347(Tyrosyl-DNA phosphodiesterase)|mint:Q9NUW8|rcsb pdb:1JY1|rcsb pdb:1MU7|rcsb pdb:1MU9|rcsb pdb:1NOP|rcsb pdb:1QZQ|rcsb pdb:1RFF|rcsb pdb:1RFI|rcsb pdb:1RG1|rcsb pdb:1RG2|rcsb pdb:1RGT|rcsb pdb:1RGU|rcsb pdb:1RH0|rcsb pdb:5NW9|rcsb pdb:5NWA|rcsb pdb:6DHU|rcsb pdb:6DIE|rcsb pdb:6DIH|rcsb pdb:6DIM|rcsb pdb:6DJD|rcsb pdb:6DJE|rcsb pdb:6DJF|rcsb pdb:6DJG|rcsb pdb:6DJH|rcsb pdb:6DJI|rcsb pdb:6DJJ|rcsb pdb:6MJ5|rcsb pdb:6MYZ|rcsb pdb:6MZ0|rcsb pdb:6N0D|rcsb pdb:6N0N|rcsb pdb:6N0O|rcsb pdb:6N0R|rcsb pdb:6N17|rcsb pdb:6N19|rcsb pdb:6W4R|rcsb pdb:6W7J|rcsb pdb:6W7K|rcsb pdb:6W7L|reactome:R-HSA-5693571|refseq:XP_011535244.1|refseq:XP_011535245.1|refseq:NP_001008744.1|refseq:NP_060789.2|refseq:XP_006720260.1|refseq:XP_006720261.1|refseq:XP_016876928.1|refseq:XP_016876931.1|refseq:XP_016876932.1|refseq:XP_016876933.1|refseq:XP_005267904.1|refseq:XP_005267905.1 ensembl:ENSG00000102226(gene)|ensembl:ENST00000218348(transcript)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR029346|interpro:IPR035927|interpro:IPR038765|mint:P51784|rcsb pdb:4MEL|rcsb pdb:5OK6|reactome:R-HSA-390471|reactome:R-HSA-5689880|refseq:NP_004642.2|refseq:XP_011542290.1|refseq:XP_005272731.1|dip:DIP-27567N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:7ain8+0TMD1xcADMpcQ0WKn4aIc9606 rogid:OSJLLFBf1ofw8SC01p2iiIM1oJo9606 rigid:/RZ7/DWVCWFJYIrH+pIUeMkLgTk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NUW8 uniprotkb:Q9Y3Y2 intact:EBI-2902553|ensembl:ENSP00000337353|ensembl:ENSP00000377099|uniprotkb:Q2HXX4|uniprotkb:Q96BK7|uniprotkb:Q9NZM7|uniprotkb:Q9NZM8|uniprotkb:Q86TV8 intact:EBI-347794|uniprotkb:Q2VPI9|uniprotkb:Q5T7Y8|uniprotkb:Q5T7Z0|uniprotkb:Q6NSM4|uniprotkb:Q6PB28|uniprotkb:Q8WYT9|uniprotkb:Q9BUC5|uniprotkb:Q9H034|uniprotkb:Q9H2L0|uniprotkb:Q0VAQ8|uniprotkb:D3DV55|uniprotkb:Q5T7Y9|ensembl:ENSP00000357683 psi-mi:tydp1_human(display_long)|uniprotkb:TDP1(gene name)|psi-mi:TDP1(display_short) psi-mi:chtop_human(display_long)|uniprotkb:HT031(orf name)|uniprotkb:PP7704(orf name)|uniprotkb:FOP(gene name synonym)|uniprotkb:CHTOP(gene name)|psi-mi:CHTOP(display_short)|uniprotkb:C1orf77(gene name synonym)|uniprotkb:Friend of PRMT1 protein(gene name synonym)|uniprotkb:Small arginine- and glycine-rich protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485749|imex:IM-26985-589 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000042088(gene)|ensembl:ENST00000335725(transcript)|ensembl:ENST00000393454(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0017005"(3'-tyrosyl-DNA phosphodiesterase activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR010347(Tyrosyl-DNA phosphodiesterase)|mint:Q9NUW8|rcsb pdb:1JY1|rcsb pdb:1MU7|rcsb pdb:1MU9|rcsb pdb:1NOP|rcsb pdb:1QZQ|rcsb pdb:1RFF|rcsb pdb:1RFI|rcsb pdb:1RG1|rcsb pdb:1RG2|rcsb pdb:1RGT|rcsb pdb:1RGU|rcsb pdb:1RH0|rcsb pdb:5NW9|rcsb pdb:5NWA|rcsb pdb:6DHU|rcsb pdb:6DIE|rcsb pdb:6DIH|rcsb pdb:6DIM|rcsb pdb:6DJD|rcsb pdb:6DJE|rcsb pdb:6DJF|rcsb pdb:6DJG|rcsb pdb:6DJH|rcsb pdb:6DJI|rcsb pdb:6DJJ|rcsb pdb:6MJ5|rcsb pdb:6MYZ|rcsb pdb:6MZ0|rcsb pdb:6N0D|rcsb pdb:6N0N|rcsb pdb:6N0O|rcsb pdb:6N0R|rcsb pdb:6N17|rcsb pdb:6N19|rcsb pdb:6W4R|rcsb pdb:6W7J|rcsb pdb:6W7K|rcsb pdb:6W7L|reactome:R-HSA-5693571|refseq:XP_011535244.1|refseq:XP_011535245.1|refseq:NP_001008744.1|refseq:NP_060789.2|refseq:XP_006720260.1|refseq:XP_006720261.1|refseq:XP_016876928.1|refseq:XP_016876931.1|refseq:XP_016876932.1|refseq:XP_016876933.1|refseq:XP_005267904.1|refseq:XP_005267905.1 refseq:NP_001304006.1|refseq:NP_001193541.1|refseq:NP_056422.2|refseq:NP_001231593.1|ensembl:ENSG00000160679(gene)|ensembl:ENST00000368694(transcript)|go:"GO:0000346"(transcription export complex)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0051096"(positive regulation of helicase activity)|interpro:IPR025715|mint:Q9Y3Y2|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:7ain8+0TMD1xcADMpcQ0WKn4aIc9606 rogid:mNq0QTGQnGABQwIL2S90Hbp3Nm89606 rigid:/RZ7/DWVCWFJYIrH+pIUeMkLgTk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NUW8 uniprotkb:P52292 intact:EBI-2902553|ensembl:ENSP00000337353|ensembl:ENSP00000377099|uniprotkb:Q2HXX4|uniprotkb:Q96BK7|uniprotkb:Q9NZM7|uniprotkb:Q9NZM8|uniprotkb:Q86TV8 intact:EBI-349938|uniprotkb:Q9BRU5|ensembl:ENSP00000504685|intact:EBI-28977049|ensembl:ENSP00000332455|ensembl:ENSP00000438483|ensembl:ENSP00000462331|ensembl:ENSP00000463602|ensembl:ENSP00000504655|uniprotkb:B9EJD6|uniprotkb:Q53YE3|intact:EBI-9377406|uniprotkb:Q6NVW7 psi-mi:tydp1_human(display_long)|uniprotkb:TDP1(gene name)|psi-mi:TDP1(display_short) psi-mi:ima1_human(display_long)|uniprotkb:KPNA2(gene name)|psi-mi:KPNA2(display_short)|uniprotkb:RCH1(gene name synonym)|uniprotkb:SRP1(gene name synonym)|uniprotkb:Karyopherin subunit alpha-2(gene name synonym)|uniprotkb:SRP1-alpha(gene name synonym)|uniprotkb:RAG cohort protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485749|imex:IM-26985-589 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000042088(gene)|ensembl:ENST00000335725(transcript)|ensembl:ENST00000393454(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0017005"(3'-tyrosyl-DNA phosphodiesterase activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR010347(Tyrosyl-DNA phosphodiesterase)|mint:Q9NUW8|rcsb pdb:1JY1|rcsb pdb:1MU7|rcsb pdb:1MU9|rcsb pdb:1NOP|rcsb pdb:1QZQ|rcsb pdb:1RFF|rcsb pdb:1RFI|rcsb pdb:1RG1|rcsb pdb:1RG2|rcsb pdb:1RGT|rcsb pdb:1RGU|rcsb pdb:1RH0|rcsb pdb:5NW9|rcsb pdb:5NWA|rcsb pdb:6DHU|rcsb pdb:6DIE|rcsb pdb:6DIH|rcsb pdb:6DIM|rcsb pdb:6DJD|rcsb pdb:6DJE|rcsb pdb:6DJF|rcsb pdb:6DJG|rcsb pdb:6DJH|rcsb pdb:6DJI|rcsb pdb:6DJJ|rcsb pdb:6MJ5|rcsb pdb:6MYZ|rcsb pdb:6MZ0|rcsb pdb:6N0D|rcsb pdb:6N0N|rcsb pdb:6N0O|rcsb pdb:6N0R|rcsb pdb:6N17|rcsb pdb:6N19|rcsb pdb:6W4R|rcsb pdb:6W7J|rcsb pdb:6W7K|rcsb pdb:6W7L|reactome:R-HSA-5693571|refseq:XP_011535244.1|refseq:XP_011535245.1|refseq:NP_001008744.1|refseq:NP_060789.2|refseq:XP_006720260.1|refseq:XP_006720261.1|refseq:XP_016876928.1|refseq:XP_016876931.1|refseq:XP_016876932.1|refseq:XP_016876933.1|refseq:XP_005267904.1|refseq:XP_005267905.1 refseq:NP_002257.1|refseq:NP_001307540.1|ensembl:ENST00000330459(transcript)|ensembl:ENST00000537025(transcript)|ensembl:ENST00000579754(transcript)|ensembl:ENST00000584026(transcript)|ensembl:ENST00000677086(transcript)|ensembl:ENST00000679078(transcript)|go:"GO:0000018"(regulation of DNA recombination)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006607"(NLS-bearing protein import into nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0016020"(membrane)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043657"(host cell)|go:"GO:0061608"(nuclear import signal receptor activity)|go:"GO:0075506"(entry of viral genome into host nucleus through nuclear pore complex via importin)|go:"GO:0098892"(extrinsic component of postsynaptic specialization membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099527"(postsynapse to nucleus signaling pathway)|go:"GO:1903902"(positive regulation of viral life cycle)|interpro:IPR000225(Armadillo)|interpro:IPR002652(Importin-alpha-like, importin-beta-binding region)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR024931|interpro:IPR032413|interpro:IPR036975|mint:P52292|rcsb pdb:1EFX|rcsb pdb:1QGK|rcsb pdb:1QGR|rcsb pdb:3FEX|ensembl:ENSG00000182481(gene)|rcsb pdb:3FEY|rcsb pdb:3WPT|rcsb pdb:4E4V|rcsb pdb:4WV6|rcsb pdb:5H43|rcsb pdb:7N8J|reactome:R-HSA-111932|reactome:R-HSA-1169408|reactome:R-HSA-168276|reactome:R-HSA-442729|reactome:R-HSA-5693548|reactome:R-HSA-9018519|ensembl:ENSP00000332455|ensembl:ENSP00000438483|ensembl:ENSP00000462331|ensembl:ENSP00000463602|ensembl:ENSP00000504655|ensembl:ENSP00000504685|dip:DIP-6205N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:7ain8+0TMD1xcADMpcQ0WKn4aIc9606 rogid:DFtAbvPxkzWJO/fRLPGxA6pEEJQ9606 rigid:/RZ7/DWVCWFJYIrH+pIUeMkLgTk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NUW8 uniprotkb:Q5T1J5 intact:EBI-2902553|ensembl:ENSP00000337353|ensembl:ENSP00000377099|uniprotkb:Q2HXX4|uniprotkb:Q96BK7|uniprotkb:Q9NZM7|uniprotkb:Q9NZM8|uniprotkb:Q86TV8 intact:EBI-5325274 psi-mi:tydp1_human(display_long)|uniprotkb:TDP1(gene name)|psi-mi:TDP1(display_short) psi-mi:chch9_human(display_long)|uniprotkb:CHCHD2P9(gene name)|psi-mi:CHCHD2P9(display_short)|uniprotkb:C9orf49(gene name synonym)|uniprotkb:CHCHD9(gene name synonym)|uniprotkb:Coiled-coil-helix-coiled-coil-helix domain-containing 2 pseudogene 9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485749|imex:IM-26985-589 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000042088(gene)|ensembl:ENST00000335725(transcript)|ensembl:ENST00000393454(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0017005"(3'-tyrosyl-DNA phosphodiesterase activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR010347(Tyrosyl-DNA phosphodiesterase)|mint:Q9NUW8|rcsb pdb:1JY1|rcsb pdb:1MU7|rcsb pdb:1MU9|rcsb pdb:1NOP|rcsb pdb:1QZQ|rcsb pdb:1RFF|rcsb pdb:1RFI|rcsb pdb:1RG1|rcsb pdb:1RG2|rcsb pdb:1RGT|rcsb pdb:1RGU|rcsb pdb:1RH0|rcsb pdb:5NW9|rcsb pdb:5NWA|rcsb pdb:6DHU|rcsb pdb:6DIE|rcsb pdb:6DIH|rcsb pdb:6DIM|rcsb pdb:6DJD|rcsb pdb:6DJE|rcsb pdb:6DJF|rcsb pdb:6DJG|rcsb pdb:6DJH|rcsb pdb:6DJI|rcsb pdb:6DJJ|rcsb pdb:6MJ5|rcsb pdb:6MYZ|rcsb pdb:6MZ0|rcsb pdb:6N0D|rcsb pdb:6N0N|rcsb pdb:6N0O|rcsb pdb:6N0R|rcsb pdb:6N17|rcsb pdb:6N19|rcsb pdb:6W4R|rcsb pdb:6W7J|rcsb pdb:6W7K|rcsb pdb:6W7L|reactome:R-HSA-5693571|refseq:XP_011535244.1|refseq:XP_011535245.1|refseq:NP_001008744.1|refseq:NP_060789.2|refseq:XP_006720260.1|refseq:XP_006720261.1|refseq:XP_016876928.1|refseq:XP_016876931.1|refseq:XP_016876932.1|refseq:XP_016876933.1|refseq:XP_005267904.1|refseq:XP_005267905.1 go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|mint:Q5T1J5 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:7ain8+0TMD1xcADMpcQ0WKn4aIc9606 rogid:nxLtnxxMIGeGK2oC3BIhcwkacSs9606 rigid:/RZ7/DWVCWFJYIrH+pIUeMkLgTk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NUW8 uniprotkb:Q8TC44 intact:EBI-2902553|ensembl:ENSP00000337353|ensembl:ENSP00000377099|uniprotkb:Q2HXX4|uniprotkb:Q96BK7|uniprotkb:Q9NZM7|uniprotkb:Q9NZM8|uniprotkb:Q86TV8 intact:EBI-1176274|ensembl:ENSP00000323302|uniprotkb:G3V1X0 psi-mi:tydp1_human(display_long)|uniprotkb:TDP1(gene name)|psi-mi:TDP1(display_short) psi-mi:poc1b_human(display_long)|uniprotkb:POC1B(gene name)|psi-mi:POC1B(display_short)|uniprotkb:WDR51B(gene name synonym)|uniprotkb:WD repeat-containing protein 51B(gene name synonym)|uniprotkb:Pix1(gene name synonym)|uniprotkb:Proteome of centriole protein 1B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485749|imex:IM-26985-589 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000042088(gene)|ensembl:ENST00000335725(transcript)|ensembl:ENST00000393454(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0017005"(3'-tyrosyl-DNA phosphodiesterase activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR010347(Tyrosyl-DNA phosphodiesterase)|mint:Q9NUW8|rcsb pdb:1JY1|rcsb pdb:1MU7|rcsb pdb:1MU9|rcsb pdb:1NOP|rcsb pdb:1QZQ|rcsb pdb:1RFF|rcsb pdb:1RFI|rcsb pdb:1RG1|rcsb pdb:1RG2|rcsb pdb:1RGT|rcsb pdb:1RGU|rcsb pdb:1RH0|rcsb pdb:5NW9|rcsb pdb:5NWA|rcsb pdb:6DHU|rcsb pdb:6DIE|rcsb pdb:6DIH|rcsb pdb:6DIM|rcsb pdb:6DJD|rcsb pdb:6DJE|rcsb pdb:6DJF|rcsb pdb:6DJG|rcsb pdb:6DJH|rcsb pdb:6DJI|rcsb pdb:6DJJ|rcsb pdb:6MJ5|rcsb pdb:6MYZ|rcsb pdb:6MZ0|rcsb pdb:6N0D|rcsb pdb:6N0N|rcsb pdb:6N0O|rcsb pdb:6N0R|rcsb pdb:6N17|rcsb pdb:6N19|rcsb pdb:6W4R|rcsb pdb:6W7J|rcsb pdb:6W7K|rcsb pdb:6W7L|reactome:R-HSA-5693571|refseq:XP_011535244.1|refseq:XP_011535245.1|refseq:NP_001008744.1|refseq:NP_060789.2|refseq:XP_006720260.1|refseq:XP_006720261.1|refseq:XP_016876928.1|refseq:XP_016876931.1|refseq:XP_016876932.1|refseq:XP_016876933.1|refseq:XP_005267904.1|refseq:XP_005267905.1 refseq:NP_758440.1|ensembl:ENSG00000139323(gene)|ensembl:ENST00000313546(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|go:"GO:0008283"(cell population proliferation)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q8TC44|refseq:NP_001186706.1 - - comment:"author score: 28" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:7ain8+0TMD1xcADMpcQ0WKn4aIc9606 rogid:wLnp5gzUvx/+G6b2BJUDopNgpOc9606 rigid:/RZ7/DWVCWFJYIrH+pIUeMkLgTk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NUW8 uniprotkb:P18887 intact:EBI-2902553|ensembl:ENSP00000337353|ensembl:ENSP00000377099|uniprotkb:Q2HXX4|uniprotkb:Q96BK7|uniprotkb:Q9NZM7|uniprotkb:Q9NZM8|uniprotkb:Q86TV8 intact:EBI-947466|uniprotkb:Q9HCB1|uniprotkb:Q6IBS4|ensembl:ENSP00000262887 psi-mi:tydp1_human(display_long)|uniprotkb:TDP1(gene name)|psi-mi:TDP1(display_short) psi-mi:xrcc1_human(display_long)|uniprotkb:XRCC1(gene name)|psi-mi:XRCC1(display_short)|uniprotkb:X-ray repair cross-complementing protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485749|imex:IM-26985-589 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000042088(gene)|ensembl:ENST00000335725(transcript)|ensembl:ENST00000393454(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0017005"(3'-tyrosyl-DNA phosphodiesterase activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR010347(Tyrosyl-DNA phosphodiesterase)|mint:Q9NUW8|rcsb pdb:1JY1|rcsb pdb:1MU7|rcsb pdb:1MU9|rcsb pdb:1NOP|rcsb pdb:1QZQ|rcsb pdb:1RFF|rcsb pdb:1RFI|rcsb pdb:1RG1|rcsb pdb:1RG2|rcsb pdb:1RGT|rcsb pdb:1RGU|rcsb pdb:1RH0|rcsb pdb:5NW9|rcsb pdb:5NWA|rcsb pdb:6DHU|rcsb pdb:6DIE|rcsb pdb:6DIH|rcsb pdb:6DIM|rcsb pdb:6DJD|rcsb pdb:6DJE|rcsb pdb:6DJF|rcsb pdb:6DJG|rcsb pdb:6DJH|rcsb pdb:6DJI|rcsb pdb:6DJJ|rcsb pdb:6MJ5|rcsb pdb:6MYZ|rcsb pdb:6MZ0|rcsb pdb:6N0D|rcsb pdb:6N0N|rcsb pdb:6N0O|rcsb pdb:6N0R|rcsb pdb:6N17|rcsb pdb:6N19|rcsb pdb:6W4R|rcsb pdb:6W7J|rcsb pdb:6W7K|rcsb pdb:6W7L|reactome:R-HSA-5693571|refseq:XP_011535244.1|refseq:XP_011535245.1|refseq:NP_001008744.1|refseq:NP_060789.2|refseq:XP_006720260.1|refseq:XP_006720261.1|refseq:XP_016876928.1|refseq:XP_016876931.1|refseq:XP_016876932.1|refseq:XP_016876933.1|refseq:XP_005267904.1|refseq:XP_005267905.1 refseq:NP_006288.2|dip:DIP-39067N|ensembl:ENSG00000073050(gene)|ensembl:ENST00000262887(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0001666"(response to hypoxia)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006284"(base-excision repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0010033"(response to organic substance)|go:"GO:0010836"(negative regulation of protein ADP-ribosylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0021587"(cerebellum morphogenesis)|go:"GO:0021766"(hippocampus development)|go:"GO:0032356"(oxidized DNA binding)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0042493"|go:"GO:0050882"(voluntary musculoskeletal movement)|go:"GO:0061819"(telomeric DNA-containing double minutes formation)|go:"GO:0070522"(ERCC4-ERCC1 complex)|go:"GO:1903518"(positive regulation of single strand break repair)|go:"GO:1904877"(positive regulation of DNA ligase activity)|go:"GO:1905765"(negative regulation of protection from non-homologous end joining at telomere)|go:"GO:1990414"(replication-born double-strand break repair via sister chromatid exchange)|go:"GO:1990599"(3' overhang single-stranded DNA endodeoxyribonuclease activity)|interpro:IPR001357(BRCT)|interpro:IPR002706(DNA-repair protein Xrcc1, N-terminal)|interpro:IPR008979(Galactose-binding like)|interpro:IPR036420|mint:P18887|rcsb pdb:1CDZ|rcsb pdb:1XNA|rcsb pdb:1XNT|rcsb pdb:2D8M|rcsb pdb:2W3O|rcsb pdb:3K75|rcsb pdb:3K77|rcsb pdb:3LQC|rcsb pdb:5E6Q|rcsb pdb:5W7X|rcsb pdb:5W7Y|reactome:R-HSA-110381|reactome:R-HSA-5649702|reactome:R-HSA-5685939|reactome:R-HSA-5696397|reactome:R-HSA-6782210 - - comment:"author score: 28" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:7ain8+0TMD1xcADMpcQ0WKn4aIc9606 rogid:96hETrBzHYhHX9FC5dZpKnFcjDg9606 rigid:/RZ7/DWVCWFJYIrH+pIUeMkLgTk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NUW8 uniprotkb:P49916 intact:EBI-2902553|ensembl:ENSP00000337353|ensembl:ENSP00000377099|uniprotkb:Q2HXX4|uniprotkb:Q96BK7|uniprotkb:Q9NZM7|uniprotkb:Q9NZM8|uniprotkb:Q86TV8 intact:EBI-1753381|intact:EBI-1058758|uniprotkb:Q16714|uniprotkb:Q6NVK3|ensembl:ENSP00000367787|uniprotkb:E5KLB5|uniprotkb:E5KLB6 psi-mi:tydp1_human(display_long)|uniprotkb:TDP1(gene name)|psi-mi:TDP1(display_short) psi-mi:dnli3_human(display_long)|uniprotkb:LIG3(gene name)|psi-mi:LIG3(display_short)|uniprotkb:DNA ligase III(gene name synonym)|uniprotkb:Polydeoxyribonucleotide synthase [ATP] 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485749|imex:IM-26985-589 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000042088(gene)|ensembl:ENST00000335725(transcript)|ensembl:ENST00000393454(transcript)|go:"GO:0000012"(single strand break repair)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0004527"(exonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0017005"(3'-tyrosyl-DNA phosphodiesterase activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR010347(Tyrosyl-DNA phosphodiesterase)|mint:Q9NUW8|rcsb pdb:1JY1|rcsb pdb:1MU7|rcsb pdb:1MU9|rcsb pdb:1NOP|rcsb pdb:1QZQ|rcsb pdb:1RFF|rcsb pdb:1RFI|rcsb pdb:1RG1|rcsb pdb:1RG2|rcsb pdb:1RGT|rcsb pdb:1RGU|rcsb pdb:1RH0|rcsb pdb:5NW9|rcsb pdb:5NWA|rcsb pdb:6DHU|rcsb pdb:6DIE|rcsb pdb:6DIH|rcsb pdb:6DIM|rcsb pdb:6DJD|rcsb pdb:6DJE|rcsb pdb:6DJF|rcsb pdb:6DJG|rcsb pdb:6DJH|rcsb pdb:6DJI|rcsb pdb:6DJJ|rcsb pdb:6MJ5|rcsb pdb:6MYZ|rcsb pdb:6MZ0|rcsb pdb:6N0D|rcsb pdb:6N0N|rcsb pdb:6N0O|rcsb pdb:6N0R|rcsb pdb:6N17|rcsb pdb:6N19|rcsb pdb:6W4R|rcsb pdb:6W7J|rcsb pdb:6W7K|rcsb pdb:6W7L|reactome:R-HSA-5693571|refseq:XP_011535244.1|refseq:XP_011535245.1|refseq:NP_001008744.1|refseq:NP_060789.2|refseq:XP_006720260.1|refseq:XP_006720261.1|refseq:XP_016876928.1|refseq:XP_016876931.1|refseq:XP_016876932.1|refseq:XP_016876933.1|refseq:XP_005267904.1|refseq:XP_005267905.1 refseq:NP_002302.2|refseq:NP_039269.2|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0051301"(cell division)|go:"GO:0070421"(DNA ligase III-XRCC1 complex)|go:"GO:0071897"(DNA biosynthetic process)|go:"GO:0090298"(negative regulation of mitochondrial DNA replication)|go:"GO:0097681"(double-strand break repair via alternative nonhomologous end joining)|interpro:IPR000977(ATP-dependent DNA ligase)|interpro:IPR001357(BRCT)|interpro:IPR001510(Zinc finger, PARP-type)|interpro:IPR012308(DNA ligase, N-terminal)|interpro:IPR012309(ATP dependent DNA ligase, C-terminal)|interpro:IPR012310(ATP dependent DNA ligase, central)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR016059(ATP-dependent DNA ligase, conserved site)|interpro:IPR031916|interpro:IPR036420|interpro:IPR036599|interpro:IPR036957|mint:P49916|rcsb pdb:1IMO|rcsb pdb:1IN1|rcsb pdb:1UW0|rcsb pdb:3L2P|rcsb pdb:3PC7|rcsb pdb:3PC8|rcsb pdb:3QVG|rcsb pdb:6WH1|reactome:R-HSA-110381|reactome:R-HSA-5649702|reactome:R-HSA-5685939|reactome:R-HSA-5696397|reactome:R-HSA-6782210|ensembl:ENSG00000005156(gene)|ensembl:ENST00000378526(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0003909"(DNA ligase activity)|go:"GO:0003910"("DNA ligase (ATP) activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006266"(DNA ligation)|go:"GO:0006273"(lagging strand elongation)|go:"GO:0006287"(base-excision repair, gap-filling)|go:"GO:0006288"(base-excision repair, DNA ligation)|go:"GO:0006302"(double-strand break repair)|refseq:XP_016880113.1 - - comment:"author score: 65" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:7ain8+0TMD1xcADMpcQ0WKn4aIc9606 rogid:+GqYPnth9+VqCoh1TvPG4yEDLeo9606 rigid:/RZ7/DWVCWFJYIrH+pIUeMkLgTk false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y2U8 uniprotkb:Q9BXT4 intact:EBI-2561428|ensembl:ENSP00000308369|uniprotkb:Q9NT47|uniprotkb:Q9NYA5 intact:EBI-1757688|uniprotkb:A6NEN3|uniprotkb:A6NMN2|uniprotkb:Q4G0Y8|uniprotkb:Q6P518|uniprotkb:Q9H7B3|uniprotkb:B3KVI4|uniprotkb:B4E2L5|uniprotkb:D3DRC2 psi-mi:man1_human(display_long)|uniprotkb:MAN1(gene name synonym)|uniprotkb:LEM domain-containing protein 3(gene name synonym)|uniprotkb:LEMD3(gene name)|psi-mi:LEMD3(display_short) psi-mi:tdrd1_human(display_long)|uniprotkb:TDRD1(gene name)|psi-mi:TDRD1(display_short)|uniprotkb:Cancer/testis antigen 41.1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25485776|imex:IM-26985-59 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000174106(gene)|ensembl:ENST00000308330(transcript)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0006998"(nuclear envelope organization)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032926"(negative regulation of activin receptor signaling pathway)|go:"GO:1902531"(regulation of intracellular signal transduction)|go:"GO:0031965"(nuclear membrane)|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|interpro:IPR011015(LEM-like fold)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018996|interpro:IPR034394|interpro:IPR034997|interpro:IPR035979|interpro:IPR041885|mint:Q9Y2U8|rcsb pdb:2CH0|rcsb pdb:5ZOJ|rcsb pdb:5ZOK|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_001161086.1|refseq:NP_055134.2 refseq:XP_011538265.1|mint:Q9BXT4|refseq:NP_942090.1|interpro:IPR002999(Tudor)|interpro:IPR002893(Zinc finger, MYND-type)|refseq:XP_011538261.1|refseq:XP_005270035.1|refseq:XP_011538262.1|refseq:XP_011538263.1|refseq:XP_011538264.1|interpro:IPR035437|go:"GO:0005737"(cytoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0033391"(chromatoid body)|go:"GO:0034587"(piRNA metabolic process)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0043186"(P granule)|go:"GO:0046872"(metal ion binding)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0071546"(pi-body)|go:"GO:1990904"(ribonucleoprotein complex)|rcsb pdb:5M9N|reactome:R-HSA-5601884 - comment:"author score: 19" - figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:8AILzxAZLbxCAzlJ7oPg9WybOmY9606 rogid:tAz+PzxhAAO9UQ6MJ6RAd67qDbg9606 rigid:MZLOy0ZSpuQlucqZoQYeYbAU5bk false - tandem tag:n-n - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:Q13185 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485890|imex:IM-26985-447 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222 go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rigid:PnK9QmqGgnu91hBaY7OLjWGcxak false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:Q7KZF4 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-1044112|uniprotkb:Q13122|ensembl:ENSP00000346762|uniprotkb:Q96AG0 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:snd1_human(display_long)|uniprotkb:100 kDa coactivator(gene name synonym)|uniprotkb:EBNA2 coactivator p100(gene name synonym)|uniprotkb:Tudor domain-containing protein 11(gene name synonym)|uniprotkb:SND1(gene name)|psi-mi:SND1(display_short)|uniprotkb:p100 co-activator(gene name synonym)|uniprotkb:TDRD11(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485890|imex:IM-26985-447 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222 refseq:NP_055205.2|ensembl:ENSG00000197157(gene)|ensembl:ENST00000354725(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0042470"(melanosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097433"(dense body)|go:"GO:1905172"(RISC complex binding)|interpro:IPR002071(Thermonuclease active site)|interpro:IPR002999(Tudor)|interpro:IPR016071("Staphylococcal nuclease (SNase-like), OB-fold")|interpro:IPR016685(RNA-induced silencing complex, nuclease component Tudor-SN)|interpro:IPR035437|mint:Q7KZF4|rcsb pdb:2E6N|rcsb pdb:2HQE|rcsb pdb:2HQX|rcsb pdb:2O4X|rcsb pdb:3BDL|rcsb pdb:3OMC|rcsb pdb:3OMG|rcsb pdb:4QMG|rcsb pdb:5M9O|reactome:R-HSA-6802952|dip:DIP-29613N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:I9JNlRfASs5dwk0JZQ+F+GsW94g9606 rigid:PnK9QmqGgnu91hBaY7OLjWGcxak false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:P61964 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485890|imex:IM-26985-447 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222 refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rigid:PnK9QmqGgnu91hBaY7OLjWGcxak false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:Q9UBQ7 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-372445|uniprotkb:Q9H3E9|uniprotkb:Q9UKX1|ensembl:ENSP00000313432|uniprotkb:Q5T945|uniprotkb:Q9H636 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:grhpr_human(display_long)|uniprotkb:MSTP035(orf name)|uniprotkb:GRHPR(gene name)|psi-mi:GRHPR(display_short)|uniprotkb:GLXR(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485890|imex:IM-26985-447 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222 refseq:NP_036335.1|go:"GO:0043648"(dicarboxylic acid metabolic process)|go:"GO:0046487"(glyoxylate metabolic process)|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070402"(NADPH binding)|go:"GO:1902494"(catalytic complex)|interpro:IPR006139(D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region)|interpro:IPR006140(D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding)|interpro:IPR029753|interpro:IPR036291|mint:Q9UBQ7|rcsb pdb:2GCG|rcsb pdb:2H1S|rcsb pdb:2Q50|rcsb pdb:2WWR|reactome:R-HSA-389661|ensembl:ENSG00000137106(gene)|ensembl:ENST00000318158(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0007588"(excretion)|go:"GO:0008465"(glycerate dehydrogenase activity)|go:"GO:0016618"(hydroxypyruvate reductase activity)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0030267"("glyoxylate reductase (NADP+) activity")|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0042803"(protein homodimerization activity) - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:qPHrh5I5wHI5MWba4zncz26cUnQ9606 rigid:PnK9QmqGgnu91hBaY7OLjWGcxak false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:Q06587 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-752313|uniprotkb:Q5JP96|uniprotkb:Q5SQW2|uniprotkb:Q86V19|uniprotkb:A8JZZ0|ensembl:ENSP00000363787|ensembl:ENSP00000372699|ensembl:ENSP00000396271|ensembl:ENSP00000396439|ensembl:ENSP00000400572|ensembl:ENSP00000412190 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:ring1_human(display_long)|uniprotkb:RING finger protein 1(gene name synonym)|uniprotkb:Polycomb complex protein RING1(gene name synonym)|uniprotkb:RING1(gene name)|psi-mi:RING1(display_short)|uniprotkb:RNF1(gene name synonym)|uniprotkb:Really interesting new gene 1 protein(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485890|imex:IM-26985-447 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222 refseq:NP_002922.2|dip:DIP-42043N|ensembl:ENSG00000204227(gene)|ensembl:ENSG00000206287(gene)|ensembl:ENSG00000226788(gene)|ensembl:ENSG00000228520(gene)|ensembl:ENSG00000231115(gene)|ensembl:ENSG00000235107(gene)|ensembl:ENST00000374656(transcript)|ensembl:ENST00000383212(transcript)|ensembl:ENST00000415941(transcript)|ensembl:ENST00000427374(transcript)|ensembl:ENST00000430233(transcript)|ensembl:ENST00000436128(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0016607"(nuclear speck)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0097027"(ubiquitin-protein transferase activator activity)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR042741|mint:Q06587|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750|interpro:IPR043540 - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:oAdj6hshWi4/CoFFW3ZwyO4LKOU9606 rigid:PnK9QmqGgnu91hBaY7OLjWGcxak false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:P61244 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-751711|intact:EBI-878388|uniprotkb:A8K265|uniprotkb:A8K4G4|uniprotkb:A8K824|uniprotkb:P25912|uniprotkb:P52163|uniprotkb:Q14803|uniprotkb:Q96CY8|uniprotkb:A6NH73|ensembl:ENSP00000351490 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:max_human(display_long)|uniprotkb:MAX(gene name)|psi-mi:MAX(display_short)|uniprotkb:BHLHD4(gene name synonym)|uniprotkb:Class D basic helix-loop-helix protein 4(gene name synonym)|uniprotkb:Myc-associated factor X(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485890|imex:IM-26985-447 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222 refseq:NP_002373.3|refseq:NP_660087.1|refseq:NP_660088.1|refseq:NP_660089.1|refseq:NP_001257997.1|refseq:NP_932061.1|dip:DIP-28145N|go:"GO:0016605"(PML body)|go:"GO:0030425"(dendrite)|go:"GO:0032868"(response to insulin)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048678"(response to axon injury)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070888"(E-box binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|ensembl:ENSG00000125952(gene)|ensembl:ENST00000358664(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0010629"(negative regulation of gene expression)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR036638|interpro:IPR037933|mint:P61244|rcsb pdb:1AN2|rcsb pdb:1HLO|rcsb pdb:1NKP|rcsb pdb:1NLW|rcsb pdb:1R05|rcsb pdb:5EYO|rcsb pdb:6G6J|rcsb pdb:6G6K|rcsb pdb:6G6L|reactome:R-HSA-1362277|reactome:R-HSA-69202|reactome:R-HSA-69656|reactome:R-HSA-8953750 - - comment:"author score: 29" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:I5d1d/zT353OsLios95yEITNoWU9606 rigid:PnK9QmqGgnu91hBaY7OLjWGcxak false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:Q15329 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-1389773|uniprotkb:Q16601|uniprotkb:Q92756|uniprotkb:E9PBN9|ensembl:ENSP00000398124 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:e2f5_human(display_long)|uniprotkb:E2F5(gene name)|psi-mi:E2F5(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485890|imex:IM-26985-447 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222 refseq:NP_001077057.1|refseq:NP_001077058.1|refseq:NP_001942.2|dip:DIP-24229N|ensembl:ENSG00000133740(gene)|ensembl:ENST00000416274(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001650"(fibrillar center)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0030030"(cell projection organization)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR028316|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:Q15329|rcsb pdb:5TUV|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-2173796|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656 - - comment:"author score: 29" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:M9xU+a14lZDS6cyMt8LF+uMMH8k9606 rigid:PnK9QmqGgnu91hBaY7OLjWGcxak false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:Q8IWI9 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-2815196|uniprotkb:E7ENI0|uniprotkb:F5H7K2|uniprotkb:Q9H9N7|uniprotkb:Q9H8R3|uniprotkb:Q9Y4E9|uniprotkb:Q9UG69|intact:EBI-11143500|intact:EBI-10969960|ensembl:ENSP00000219905|uniprotkb:B9EGR5 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:mgap_human(display_long)|uniprotkb:MGA(gene name)|psi-mi:MGA(display_short)|uniprotkb:KIAA0518(gene name synonym)|uniprotkb:MAD5(gene name synonym)|uniprotkb:MAX dimerization protein 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485890|imex:IM-26985-447 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222 refseq:NP_001074010.2|ensembl:ENSP00000219905|ensembl:ENST00000566586|ensembl:ENSP00000456141|ensembl:ENSG00000174197(gene)|ensembl:ENST00000219905(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR018186|interpro:IPR032060|interpro:IPR036638|interpro:IPR036960|interpro:IPR037935|mint:Q8IWI9|reactome:R-HSA-8953750|refseq:NP_001157745.1|dip:DIP-57615N - - comment:"author score: 32" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:P4lo9EteCvikQQk5kyVkcobitLU9606 rigid:PnK9QmqGgnu91hBaY7OLjWGcxak false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:Q9BYE7 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485890|imex:IM-26985-447 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222 refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N - - comment:"author score: 39" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 rigid:PnK9QmqGgnu91hBaY7OLjWGcxak false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:P06400 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-491274|uniprotkb:P78499|uniprotkb:Q5VW46|uniprotkb:Q8IZL4|uniprotkb:A8K5E3|ensembl:ENSP00000267163 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:rb_human(display_long)|uniprotkb:pRb(gene name synonym)|uniprotkb:pp110(gene name synonym)|uniprotkb:p105-Rb(gene name synonym)|uniprotkb:RB1(gene name)|psi-mi:RB1(display_short)|uniprotkb:p110-RB1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485890|imex:IM-26985-447 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222 go:"GO:1903055"(positive regulation of extracellular matrix organization)|refseq:NP_000312.2|go:"GO:1904028"(positive regulation of collagen fibril organization)|go:"GO:1904761"(negative regulation of myofibroblast differentiation)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR002719(Retinoblastoma-associated protein, B-box)|interpro:IPR002720(Retinoblastoma-associated protein, A-box)|interpro:IPR013763(Cyclin-related)|interpro:IPR015030(Rb C-terminal)|interpro:IPR024599|interpro:IPR028309|interpro:IPR036915|mint:P06400|rcsb pdb:1AD6|rcsb pdb:1GH6|rcsb pdb:1GUX|rcsb pdb:1H25|rcsb pdb:1N4M|rcsb pdb:1O9K|rcsb pdb:1PJM|rcsb pdb:2AZE|rcsb pdb:2QDJ|rcsb pdb:2R7G|rcsb pdb:3N5U|rcsb pdb:3POM|rcsb pdb:4CRI|rcsb pdb:4ELJ|rcsb pdb:4ELL|reactome:R-HSA-113501|reactome:R-HSA-174178|reactome:R-HSA-2299718|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-69200|reactome:R-HSA-69202|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8940973|reactome:R-HSA-9661069|reactome:R-HSA-9661070|reactome:R-HSA-9682706|reactome:R-HSA-9687136|reactome:R-HSA-9694686|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016514"(SWI/SNF complex)|go:"GO:0016605"(PML body)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0019900"(kinase binding)|go:"GO:0030154"(cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031134"(sister chromatid biorientation)|go:"GO:0031175"(neuron projection development)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034088"(maintenance of mitotic sister chromatid cohesion)|go:"GO:0034349"(glial cell apoptotic process)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042551"(neuron maturation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043353"(enucleate erythrocyte differentiation)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043550"(regulation of lipid kinase activity)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0045651"(positive regulation of macrophage differentiation)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045842"(positive regulation of mitotic metaphase/anaphase transition)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048565"(digestive tract development)|go:"GO:0048667"(cell morphogenesis involved in neuron differentiation)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0071459"(protein localization to chromosome, centromeric region)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0071922"(regulation of cohesin loading)|go:"GO:0071930"(negative regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0090230"(regulation of centromere complex assembly)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902948"(negative regulation of tau-protein kinase activity)|ensembl:ENSG00000139687(gene)|ensembl:ENST00000267163(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|dip:DIP-582N - - comment:"author score: 42" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:xidCNX96KlQzu160polvT61k4Zw9606 rigid:PnK9QmqGgnu91hBaY7OLjWGcxak false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:Q969R5 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-739909|uniprotkb:Q8TEN1|uniprotkb:Q96SC4|uniprotkb:Q9BQI2|uniprotkb:Q9UGS4|ensembl:ENSP00000216237 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:lmbl2_human(display_long)|uniprotkb:L3MBTL2(gene name)|psi-mi:L3MBTL2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485890|imex:IM-26985-447 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222 refseq:NP_113676.2|dip:DIP-56748N|ensembl:ENSG00000100395(gene)|ensembl:ENST00000216237(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|interpro:IPR004092(Mbt repeat)|interpro:IPR012313(Zinc finger, FCS-type)|interpro:IPR038038|interpro:IPR038603|mint:Q969R5|rcsb pdb:2W0T|rcsb pdb:3CEY|rcsb pdb:3F70|reactome:R-HSA-4551638|reactome:R-HSA-8953750 - - comment:"author score: 43" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:2N5SDa6kSvtM/PlPu5gHXzY8e3Q9606 rigid:PnK9QmqGgnu91hBaY7OLjWGcxak false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:Q14209 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-718476|uniprotkb:Q7Z6H1|uniprotkb:B2R9W1|ensembl:ENSP00000355249|ensembl:ENSP00000489612 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:e2f2_human(display_long)|uniprotkb:E2F2(gene name)|psi-mi:E2F2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485890|imex:IM-26985-447 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222 refseq:NP_004082.1|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|go:"GO:1990086"(lens fiber cell apoptotic process)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:Q14209|rcsb pdb:1N4M|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-69231|reactome:R-HSA-9661069|ensembl:ENSG00000007968(gene)|ensembl:ENSG00000282899(gene)|ensembl:ENST00000361729(transcript)|ensembl:ENST00000634683(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|dip:DIP-258N - - comment:"author score: 56" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:mTyyEcashAWBpjb0viYJv5OiREY9606 rigid:PnK9QmqGgnu91hBaY7OLjWGcxak false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:Q01094 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-448924|uniprotkb:Q13143|uniprotkb:Q92768|ensembl:ENSP00000345571 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:e2f1_human(display_long)|uniprotkb:Retinoblastoma-associated protein 1(gene name synonym)|uniprotkb:Retinoblastoma-binding protein 3(gene name synonym)|uniprotkb:PBR3(gene name synonym)|uniprotkb:E2F1(gene name)|psi-mi:E2F1(display_short)|uniprotkb:RBBP3(gene name synonym)|uniprotkb:pRB-binding protein E2F-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485890|imex:IM-26985-447 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222 refseq:NP_005216.1|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071466"(cellular response to xenobiotic stimulus)|go:"GO:0071930"(negative regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990086"(lens fiber cell apoptotic process)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030900"(forebrain development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035189"(Rb-E2F complex)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043276"(anoikis)|go:"GO:0043392"(negative regulation of DNA binding)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048255"(mRNA stabilization)|ensembl:ENSG00000101412(gene)|ensembl:ENST00000343380(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804116|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:Q01094|rcsb pdb:1H24|rcsb pdb:1O9K|rcsb pdb:2AZE|rcsb pdb:5M9N|rcsb pdb:5M9O|rcsb pdb:6G0P|rcsb pdb:6ULS|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1912408|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9616222|reactome:R-HSA-9661069|dip:DIP-24227N - - comment:"author score: 56" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:vPNenpmxyXpHjMzUID54cwMFk+Y9606 rigid:PnK9QmqGgnu91hBaY7OLjWGcxak false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:O75461 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485890|imex:IM-26985-447 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222 refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198 - - comment:"author score: 72" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rigid:PnK9QmqGgnu91hBaY7OLjWGcxak false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:O00716 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-765551|uniprotkb:Q15000|uniprotkb:Q9BZ44|uniprotkb:Q68DT0|intact:EBI-28986746|ensembl:ENSP00000262904 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:e2f3_human(display_long)|uniprotkb:E2F3(gene name)|psi-mi:E2F3(display_short)|uniprotkb:KIAA0075(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485890|imex:IM-26985-447 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222 refseq:NP_001940.1|ensembl:ENSP00000262904|ensembl:ENST00000535432|ensembl:ENSP00000443418|refseq:NP_001230005.1|dip:DIP-24230N|ensembl:ENSG00000112242(gene)|ensembl:ENST00000346618(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006367"(transcription initiation from RNA polymerase II promoter)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O00716|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-68689|reactome:R-HSA-68911|reactome:R-HSA-69231|reactome:R-HSA-9661069|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process) - - comment:"author score: 75" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:xbS+FGeyfs03y8Jh5/M5L9y9sdU9606 rigid:PnK9QmqGgnu91hBaY7OLjWGcxak false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14186 uniprotkb:Q16254 intact:EBI-749713|uniprotkb:Q8IZL5|uniprotkb:Q5JSB4|uniprotkb:B4DLQ9|ensembl:ENSP00000364519 intact:EBI-448943|uniprotkb:A6NGR8|uniprotkb:Q12991|uniprotkb:Q15328|uniprotkb:B5BU56|ensembl:ENSP00000368686 psi-mi:tfdp1_human(display_long)|uniprotkb:E2F dimerization partner 1(gene name synonym)|uniprotkb:DRTF1-polypeptide 1(gene name synonym)|uniprotkb:TFDP1(gene name)|psi-mi:TFDP1(display_short)|uniprotkb:DP1(gene name synonym) psi-mi:e2f4_human(display_long)|uniprotkb:E2F4(gene name)|psi-mi:E2F4(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485890|imex:IM-26985-447 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_009042.1|refseq:XP_005268388.1|refseq:XP_005268384.1|dip:DIP-238N|ensembl:ENSG00000198176(gene)|ensembl:ENST00000375370(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008544"(epidermis development)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043276"(anoikis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070345"(negative regulation of fat cell proliferation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:2000278"(regulation of DNA biosynthetic process)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR014889(Transcription factor DP, C-terminal)|interpro:IPR015648(Transcription factor DP)|interpro:IPR028313|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|interpro:IPR038168|mint:Q14186|rcsb pdb:2AZE|rcsb pdb:5GOW|rcsb pdb:5TUU|rcsb pdb:5TUV|reactome:R-HSA-111448|reactome:R-HSA-113501|reactome:R-HSA-1362277|reactome:R-HSA-1362300|reactome:R-HSA-139915|reactome:R-HSA-1538133|reactome:R-HSA-1912408|reactome:R-HSA-2173796|reactome:R-HSA-2559580|reactome:R-HSA-2559585|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|reactome:R-HSA-8953750|reactome:R-HSA-9661069|reactome:R-HSA-9616222 refseq:NP_001941.2|reactome:R-HSA-1362300|reactome:R-HSA-1538133|reactome:R-HSA-2173796|reactome:R-HSA-6804114|reactome:R-HSA-69202|reactome:R-HSA-69205|reactome:R-HSA-69231|reactome:R-HSA-69656|ensembl:ENSG00000205250(gene)|ensembl:ENST00000379378(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0002064"(epithelial cell development)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0008015"(blood circulation)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0098534"(centriole assembly)|go:"GO:1903251"(multi-ciliated epithelial cell differentiation)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR028312|interpro:IPR032198|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:Q16254|rcsb pdb:1CF7|rcsb pdb:5TUU|reactome:R-HSA-1362277|dip:DIP-24185N - - comment:"author score: 75" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:FvCKBqPptRL9BKBmt+F9kA7oU8k9606 rogid:t0tCW85omHMU3lVgYWEXNeX1sTI9606 rigid:PnK9QmqGgnu91hBaY7OLjWGcxak false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H7E2 uniprotkb:Q96I24 intact:EBI-3938232|uniprotkb:Q6P992|uniprotkb:B2MWP9|uniprotkb:Q53XA6|ensembl:ENSP00000196169|ensembl:ENSP00000367126|ensembl:ENSP00000498191 intact:EBI-954200|ensembl:ENSP00000318177|uniprotkb:Q92946|uniprotkb:Q9BVB6|intact:EBI-1760333|intact:EBI-1965411|uniprotkb:A3KFL0|uniprotkb:A3KFK8 psi-mi:tdrd3_human(display_long)|uniprotkb:TDRD3(gene name)|psi-mi:TDRD3(display_short) psi-mi:fubp3_human(display_long)|uniprotkb:FUBP3(gene name)|psi-mi:FUBP3(display_short)|uniprotkb:FBP3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485785|imex:IM-26985-369 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000083544(gene)|ensembl:ENST00000196169(transcript)|ensembl:ENST00000377894(transcript)|ensembl:ENST00000648252(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0035064"(methylated histone binding)|interpro:IPR002999(Tudor)|interpro:IPR009060(UBA-like)|interpro:IPR013894(Region of unknown function DUF1767)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR041915|interpro:IPR042470|mint:Q9H7E2|rcsb pdb:1WJI|rcsb pdb:2LTO|rcsb pdb:3PMT|rcsb pdb:3PNW|rcsb pdb:3S6W|rcsb pdb:5GVD|rcsb pdb:5GVE|rcsb pdb:5YJ8|rcsb pdb:6V9T|refseq:NP_001139542.1|refseq:NP_001139543.1|refseq:NP_110421.1|refseq:XP_016876266.1|dip:DIP-61935N ensembl:ENSG00000107164(gene)|ensembl:ENST00000319725(transcript)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q96I24|refseq:NP_003925.1|dip:DIP-50124N - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Fao3X109d50ZnSif4TMnx/seheA9606 rogid:xdCa+teqFaSxKNTpCJWQ5gcd0sQ9606 rigid:EmRrCMEXsF0tXI9sKW2WH/hwV7U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H7E2 uniprotkb:Q8TC44 intact:EBI-3938232|uniprotkb:Q6P992|uniprotkb:B2MWP9|uniprotkb:Q53XA6|ensembl:ENSP00000196169|ensembl:ENSP00000367126|ensembl:ENSP00000498191 intact:EBI-1176274|ensembl:ENSP00000323302|uniprotkb:G3V1X0 psi-mi:tdrd3_human(display_long)|uniprotkb:TDRD3(gene name)|psi-mi:TDRD3(display_short) psi-mi:poc1b_human(display_long)|uniprotkb:POC1B(gene name)|psi-mi:POC1B(display_short)|uniprotkb:WDR51B(gene name synonym)|uniprotkb:WD repeat-containing protein 51B(gene name synonym)|uniprotkb:Pix1(gene name synonym)|uniprotkb:Proteome of centriole protein 1B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485785|imex:IM-26985-369 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000083544(gene)|ensembl:ENST00000196169(transcript)|ensembl:ENST00000377894(transcript)|ensembl:ENST00000648252(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0035064"(methylated histone binding)|interpro:IPR002999(Tudor)|interpro:IPR009060(UBA-like)|interpro:IPR013894(Region of unknown function DUF1767)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR041915|interpro:IPR042470|mint:Q9H7E2|rcsb pdb:1WJI|rcsb pdb:2LTO|rcsb pdb:3PMT|rcsb pdb:3PNW|rcsb pdb:3S6W|rcsb pdb:5GVD|rcsb pdb:5GVE|rcsb pdb:5YJ8|rcsb pdb:6V9T|refseq:NP_001139542.1|refseq:NP_001139543.1|refseq:NP_110421.1|refseq:XP_016876266.1|dip:DIP-61935N refseq:NP_758440.1|ensembl:ENSG00000139323(gene)|ensembl:ENST00000313546(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0007099"(centriole replication)|go:"GO:0008283"(cell population proliferation)|go:"GO:0036064"(ciliary basal body)|go:"GO:0060271"(cilium assembly)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q8TC44|refseq:NP_001186706.1 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Fao3X109d50ZnSif4TMnx/seheA9606 rogid:wLnp5gzUvx/+G6b2BJUDopNgpOc9606 rigid:EmRrCMEXsF0tXI9sKW2WH/hwV7U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H7E2 uniprotkb:Q06787 intact:EBI-3938232|uniprotkb:Q6P992|uniprotkb:B2MWP9|uniprotkb:Q53XA6|ensembl:ENSP00000196169|ensembl:ENSP00000367126|ensembl:ENSP00000498191 intact:EBI-366305|ensembl:ENSP00000359506|uniprotkb:Q5PQZ6|uniprotkb:Q16578|uniprotkb:Q99054|uniprotkb:A6NNH4|uniprotkb:D3DWT0|uniprotkb:D3DWT1|uniprotkb:D3DWT2|uniprotkb:G8JL90 psi-mi:tdrd3_human(display_long)|uniprotkb:TDRD3(gene name)|psi-mi:TDRD3(display_short) psi-mi:fmr1_human(display_long)|uniprotkb:FMR1(gene name)|psi-mi:FMR1(display_short)|uniprotkb:Fragile X mental retardation protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485785|imex:IM-26985-369 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000083544(gene)|ensembl:ENST00000196169(transcript)|ensembl:ENST00000377894(transcript)|ensembl:ENST00000648252(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0035064"(methylated histone binding)|interpro:IPR002999(Tudor)|interpro:IPR009060(UBA-like)|interpro:IPR013894(Region of unknown function DUF1767)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR041915|interpro:IPR042470|mint:Q9H7E2|rcsb pdb:1WJI|rcsb pdb:2LTO|rcsb pdb:3PMT|rcsb pdb:3PNW|rcsb pdb:3S6W|rcsb pdb:5GVD|rcsb pdb:5GVE|rcsb pdb:5YJ8|rcsb pdb:6V9T|refseq:NP_001139542.1|refseq:NP_001139543.1|refseq:NP_110421.1|refseq:XP_016876266.1|dip:DIP-61935N ensembl:ENSG00000102081(gene)|ensembl:ENST00000370475(transcript)|refseq:NP_001172004.1|refseq:NP_001172005.1|refseq:NP_001172010.1|refseq:NP_001172011.1|refseq:NP_002015.1|go:"GO:0043204"(perikaryon)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0034046"("poly(G) binding")|go:"GO:0034644"(cellular response to UV)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035197"(siRNA binding)|go:"GO:0035198"(miRNA binding)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042995"(cell projection)|go:"GO:0043005"(neuron projection)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043679"(axon terminus)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0046928"(regulation of neurotransmitter secretion)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051028"(mRNA transport)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060964"(regulation of gene silencing by miRNA)|go:"GO:0060998"(regulation of dendritic spine development)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070840"(dynein complex binding)|go:"GO:0071598"(neuronal ribonucleoprotein granule)|go:"GO:0072711"(cellular response to hydroxyurea)|go:"GO:0097386"(glial cell projection)|go:"GO:0098586"(cellular response to virus)|go:"GO:0098793"(presynapse)|go:"GO:0098794"(postsynapse)|go:"GO:0098908"(regulation of neuronal action potential)|go:"GO:1900453"(negative regulation of long-term synaptic depression)|go:"GO:1901254"(positive regulation of intracellular transport of viral material)|go:"GO:1901386"(negative regulation of voltage-gated calcium channel activity)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1902373"(negative regulation of mRNA catabolic process)|go:"GO:1902416"(positive regulation of mRNA binding)|go:"GO:1902737"(dendritic filopodium)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990812"(growth cone filopodium)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000301"(negative regulation of synaptic vesicle exocytosis)|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:Q06787|rcsb pdb:2BKD|rcsb pdb:2FMR|rcsb pdb:2LA5|rcsb pdb:2QND|rcsb pdb:4OVA|rcsb pdb:4QVZ|rcsb pdb:4QW2|rcsb pdb:5DE5|rcsb pdb:5DE8|rcsb pdb:5DEA|rcsb pdb:5UWJ|rcsb pdb:5UWO|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2000766"(negative regulation of cytoplasmic translation)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032196|interpro:IPR036612|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005845"(mRNA cap binding complex)|go:"GO:0006397"(mRNA processing)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007215"(glutamate receptor signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0008017"(microtubule binding)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008380"(RNA splicing)|go:"GO:0010369"(chromocenter)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015030"(Cajal body)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030371"(translation repressor activity)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030426"(growth cone)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0032433"(filopodium tip)|go:"GO:0033129"(positive regulation of histone phosphorylation)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|dip:DIP-29509N - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Fao3X109d50ZnSif4TMnx/seheA9606 rogid:+iN/J/MbxTcRwgDezYseEDwLep49606 rigid:EmRrCMEXsF0tXI9sKW2WH/hwV7U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H7E2 uniprotkb:P51114 intact:EBI-3938232|uniprotkb:Q6P992|uniprotkb:B2MWP9|uniprotkb:Q53XA6|ensembl:ENSP00000196169|ensembl:ENSP00000367126|ensembl:ENSP00000498191 intact:EBI-713291|uniprotkb:A8K9B8|uniprotkb:Q7Z450|uniprotkb:Q8N6R8|ensembl:ENSP00000350170 psi-mi:tdrd3_human(display_long)|uniprotkb:TDRD3(gene name)|psi-mi:TDRD3(display_short) psi-mi:fxr1_human(display_long)|uniprotkb:FXR1(gene name)|psi-mi:FXR1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485785|imex:IM-26985-369 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000083544(gene)|ensembl:ENST00000196169(transcript)|ensembl:ENST00000377894(transcript)|ensembl:ENST00000648252(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0035064"(methylated histone binding)|interpro:IPR002999(Tudor)|interpro:IPR009060(UBA-like)|interpro:IPR013894(Region of unknown function DUF1767)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR041915|interpro:IPR042470|mint:Q9H7E2|rcsb pdb:1WJI|rcsb pdb:2LTO|rcsb pdb:3PMT|rcsb pdb:3PNW|rcsb pdb:3S6W|rcsb pdb:5GVD|rcsb pdb:5GVE|rcsb pdb:5YJ8|rcsb pdb:6V9T|refseq:NP_001139542.1|refseq:NP_001139543.1|refseq:NP_110421.1|refseq:XP_016876266.1|dip:DIP-61935N refseq:NP_001013456.1|refseq:NP_001013457.1|refseq:NP_005078.2|go:"GO:0007517"(muscle organ development)|ensembl:ENSG00000114416(gene)|ensembl:ENST00000357559(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0060538"(skeletal muscle organ development)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR032177|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|go:"GO:0014069"(postsynaptic density)|rcsb pdb:2CPQ|rcsb pdb:3KUF|rcsb pdb:3O8V|reactome:R-HSA-6802952|mint:P51114|dip:DIP-40789N - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Fao3X109d50ZnSif4TMnx/seheA9606 rogid:pUW5/sakWOiRtZpigPhEMOPJBpk9606 rigid:EmRrCMEXsF0tXI9sKW2WH/hwV7U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H7E2 uniprotkb:P61626 intact:EBI-3938232|uniprotkb:Q6P992|uniprotkb:B2MWP9|uniprotkb:Q53XA6|ensembl:ENSP00000196169|ensembl:ENSP00000367126|ensembl:ENSP00000498191 intact:EBI-355360|ensembl:ENSP00000261267|uniprotkb:P00695|uniprotkb:Q9UCF8|uniprotkb:Q13170 psi-mi:tdrd3_human(display_long)|uniprotkb:TDRD3(gene name)|psi-mi:TDRD3(display_short) psi-mi:lysc_human(display_long)|uniprotkb:LYZ(gene name)|psi-mi:LYZ(display_short)|uniprotkb:LZM(gene name synonym)|uniprotkb:1,4-beta-N-acetylmuramidase C(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485785|imex:IM-26985-369 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000083544(gene)|ensembl:ENST00000196169(transcript)|ensembl:ENST00000377894(transcript)|ensembl:ENST00000648252(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0035064"(methylated histone binding)|interpro:IPR002999(Tudor)|interpro:IPR009060(UBA-like)|interpro:IPR013894(Region of unknown function DUF1767)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR041915|interpro:IPR042470|mint:Q9H7E2|rcsb pdb:1WJI|rcsb pdb:2LTO|rcsb pdb:3PMT|rcsb pdb:3PNW|rcsb pdb:3S6W|rcsb pdb:5GVD|rcsb pdb:5GVE|rcsb pdb:5YJ8|rcsb pdb:6V9T|refseq:NP_001139542.1|refseq:NP_001139543.1|refseq:NP_110421.1|refseq:XP_016876266.1|dip:DIP-61935N ensembl:ENSG00000090382(gene)|refseq:NP_000230.1|rcsb pdb:1GB7|rcsb pdb:1GB8|rcsb pdb:1GB9|rcsb pdb:1GBO|rcsb pdb:1GBW|rcsb pdb:1GBX|rcsb pdb:1GBY|rcsb pdb:1GBZ|rcsb pdb:1GDW|rcsb pdb:1GDX|rcsb pdb:1GE0|rcsb pdb:1GE1|rcsb pdb:1GE2|rcsb pdb:1GE3|rcsb pdb:1GE4|rcsb pdb:1GEV|rcsb pdb:1GEZ|rcsb pdb:1GF0|rcsb pdb:1GF3|rcsb pdb:1GF4|rcsb pdb:1GF5|rcsb pdb:1GF6|rcsb pdb:1GF7|rcsb pdb:1GF8|rcsb pdb:1GF9|rcsb pdb:1GFA|rcsb pdb:1GFE|rcsb pdb:1GFG|rcsb pdb:1GFH|rcsb pdb:1GFJ|rcsb pdb:1GFK|rcsb pdb:1GFR|rcsb pdb:1GFT|rcsb pdb:1GFU|rcsb pdb:1GFV|rcsb pdb:1HNL|rcsb pdb:1I1Z|rcsb pdb:1I20|rcsb pdb:1I22|rcsb pdb:1INU|rcsb pdb:1IOC|rcsb pdb:1IP1|rcsb pdb:1IP2|rcsb pdb:1IP3|rcsb pdb:1IP4|rcsb pdb:1IP5|rcsb pdb:1IP6|rcsb pdb:1IP7|rcsb pdb:1IWT|rcsb pdb:1IWU|rcsb pdb:1IWV|rcsb pdb:1IWW|rcsb pdb:1IWX|rcsb pdb:1IWY|rcsb pdb:1IWZ|rcsb pdb:1IX0|rcsb pdb:1IY3|rcsb pdb:1IY4|rcsb pdb:1JKA|rcsb pdb:1JKB|rcsb pdb:1JKC|rcsb pdb:1JKD|rcsb pdb:1JSF|rcsb pdb:1JWR|rcsb pdb:1LAA|rcsb pdb:1LHH|rcsb pdb:1LHI|rcsb pdb:1LHJ|rcsb pdb:1LHK|rcsb pdb:1LHL|rcsb pdb:1LHM|rcsb pdb:1LMT|rcsb pdb:1LOZ|rcsb pdb:1LYY|rcsb pdb:1LZ1|rcsb pdb:1LZ4|rcsb pdb:1LZ5|rcsb pdb:1LZ6|rcsb pdb:1LZR|rcsb pdb:1LZS|rcsb pdb:1OP9|rcsb pdb:1OUA|rcsb pdb:1OUB|rcsb pdb:1OUC|rcsb pdb:1OUD|rcsb pdb:1OUE|rcsb pdb:1OUF|rcsb pdb:1OUG|rcsb pdb:1OUH|rcsb pdb:1OUI|rcsb pdb:1OUJ|rcsb pdb:1QSW|rcsb pdb:1RE2|rcsb pdb:1REM|rcsb pdb:1REX|rcsb pdb:1REY|rcsb pdb:1REZ|rcsb pdb:1TAY|rcsb pdb:1TBY|rcsb pdb:1TCY|rcsb pdb:1TDY|rcsb pdb:1UBZ|rcsb pdb:5LVK|rcsb pdb:6LFH|reactome:R-HSA-6798695|reactome:R-HSA-6803157|reactome:R-HSA-977225|rcsb pdb:1W08|rcsb pdb:1WQM|rcsb pdb:1WQN|rcsb pdb:1WQO|rcsb pdb:1WQP|rcsb pdb:1WQQ|rcsb pdb:1WQR|rcsb pdb:1YAM|rcsb pdb:1YAN|rcsb pdb:1YAO|rcsb pdb:1YAP|rcsb pdb:1YAQ|rcsb pdb:207L|rcsb pdb:208L|rcsb pdb:2BQA|rcsb pdb:2BQB|rcsb pdb:2BQC|rcsb pdb:2BQD|rcsb pdb:2BQE|rcsb pdb:2BQF|rcsb pdb:2BQG|rcsb pdb:2BQH|rcsb pdb:2BQI|rcsb pdb:2BQJ|rcsb pdb:2BQK|rcsb pdb:2BQL|rcsb pdb:2BQM|rcsb pdb:2BQN|rcsb pdb:2BQO|rcsb pdb:2HEA|rcsb pdb:2HEB|rcsb pdb:2HEC|rcsb pdb:2HED|rcsb pdb:2HEE|rcsb pdb:2HEF|rcsb pdb:2LHM|rcsb pdb:2MEA|rcsb pdb:2MEB|rcsb pdb:2MEC|rcsb pdb:2MED|rcsb pdb:2MEE|rcsb pdb:2MEF|rcsb pdb:2MEG|rcsb pdb:2MEH|rcsb pdb:2MEI|rcsb pdb:2NWD|rcsb pdb:2ZIJ|rcsb pdb:2ZIK|rcsb pdb:2ZIL|rcsb pdb:2ZWB|rcsb pdb:3EBA|rcsb pdb:3FE0|rcsb pdb:3LHM|rcsb pdb:3LN2|rcsb pdb:4I0C|rcsb pdb:4ML7|rcsb pdb:4R0P|rcsb pdb:5LSH|rcsb pdb:1B5X|rcsb pdb:1B5Y|rcsb pdb:1B5Z|rcsb pdb:1B7L|rcsb pdb:1B7M|rcsb pdb:1B7N|rcsb pdb:1B7O|rcsb pdb:1B7P|rcsb pdb:1B7Q|rcsb pdb:1B7R|rcsb pdb:1B7S|rcsb pdb:1BB3|rcsb pdb:1BB4|rcsb pdb:1BB5|rcsb pdb:1C43|rcsb pdb:1C45|rcsb pdb:1C46|rcsb pdb:1C7P|rcsb pdb:1CJ6|rcsb pdb:1CJ7|rcsb pdb:1CJ8|ensembl:ENST00000261267(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0003796"(lysozyme activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006954"(inflammatory response)|go:"GO:0008152"(metabolic process)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0019835"(cytolysis)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0042802"(identical protein binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR000974(Glycoside hydrolase, family 22, lysozyme)|interpro:IPR001916(Glycoside hydrolase, family 22)|interpro:IPR019799|interpro:IPR023346|interpro:IPR030056|mint:P61626|rcsb pdb:133L|rcsb pdb:134L|rcsb pdb:1B5U|rcsb pdb:1B5V|rcsb pdb:1B5W|rcsb pdb:1CJ9|rcsb pdb:1CKC|rcsb pdb:1CKD|rcsb pdb:1CKF|rcsb pdb:1CKG|rcsb pdb:1CKH|rcsb pdb:1D6P|rcsb pdb:1D6Q|rcsb pdb:1DI3|rcsb pdb:1DI4|rcsb pdb:1DI5|rcsb pdb:1EQ4|rcsb pdb:1EQ5|rcsb pdb:1EQE|rcsb pdb:1GAY|rcsb pdb:1GAZ|rcsb pdb:1GB0|rcsb pdb:1GB2|rcsb pdb:1GB3|rcsb pdb:1GB5|rcsb pdb:1GB6 - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Fao3X109d50ZnSif4TMnx/seheA9606 rogid:jydNN9yuU9EYvnth+kv115svRxw9606 rigid:EmRrCMEXsF0tXI9sKW2WH/hwV7U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H7E2 uniprotkb:P12273 intact:EBI-3938232|uniprotkb:Q6P992|uniprotkb:B2MWP9|uniprotkb:Q53XA6|ensembl:ENSP00000196169|ensembl:ENSP00000367126|ensembl:ENSP00000498191 intact:EBI-1049746|uniprotkb:A0A963|uniprotkb:A0A9C3|uniprotkb:A0A9F3|uniprotkb:A4D2I1|ensembl:ENSP00000291009 psi-mi:tdrd3_human(display_long)|uniprotkb:TDRD3(gene name)|psi-mi:TDRD3(display_short) psi-mi:pip_human(display_long)|uniprotkb:Prolactin-induced protein(gene name synonym)|uniprotkb:Secretory actin-binding protein(gene name synonym)|uniprotkb:Gross cystic disease fluid protein 15(gene name synonym)|uniprotkb:gp17(gene name synonym)|uniprotkb:PIP(gene name)|psi-mi:PIP(display_short)|uniprotkb:GCDFP15(gene name synonym)|uniprotkb:GPIP4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485785|imex:IM-26985-369 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000083544(gene)|ensembl:ENST00000196169(transcript)|ensembl:ENST00000377894(transcript)|ensembl:ENST00000648252(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0035064"(methylated histone binding)|interpro:IPR002999(Tudor)|interpro:IPR009060(UBA-like)|interpro:IPR013894(Region of unknown function DUF1767)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR041915|interpro:IPR042470|mint:Q9H7E2|rcsb pdb:1WJI|rcsb pdb:2LTO|rcsb pdb:3PMT|rcsb pdb:3PNW|rcsb pdb:3S6W|rcsb pdb:5GVD|rcsb pdb:5GVE|rcsb pdb:5YJ8|rcsb pdb:6V9T|refseq:NP_001139542.1|refseq:NP_001139543.1|refseq:NP_110421.1|refseq:XP_016876266.1|dip:DIP-61935N refseq:NP_002643.1|ensembl:ENSG00000159763(gene)|ensembl:ENST00000291009(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0002682"(regulation of immune system process)|go:"GO:0003779"(actin binding)|go:"GO:0004190"(aspartic-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0006508"(proteolysis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019864"(IgG binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070233"(negative regulation of T cell apoptotic process)|interpro:IPR007990(Seminal vesicle autoantigen)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|mint:P12273|rcsb pdb:3ES6|reactome:R-HSA-5223345|go:"GO:0001580"(detection of chemical stimulus involved in sensory perception of bitter taste) - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Fao3X109d50ZnSif4TMnx/seheA9606 rogid:/OC16zeRzFp520uPPLHh+WekPPc9606 rigid:EmRrCMEXsF0tXI9sKW2WH/hwV7U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H7E2 uniprotkb:P48634 intact:EBI-3938232|uniprotkb:Q6P992|uniprotkb:B2MWP9|uniprotkb:Q53XA6|ensembl:ENSP00000196169|ensembl:ENSP00000367126|ensembl:ENSP00000498191 intact:EBI-347545|uniprotkb:Q05BK4|uniprotkb:Q4LE37|uniprotkb:Q8MGQ9|uniprotkb:O95875|uniprotkb:Q5SQ29|uniprotkb:Q5SQ30|uniprotkb:Q5ST84|uniprotkb:Q5STX6|uniprotkb:Q5STX7|uniprotkb:Q68DW9|uniprotkb:Q6P9P7|uniprotkb:Q6PIN1|uniprotkb:Q96QC6|uniprotkb:B0UZL3|uniprotkb:B0UZE9|uniprotkb:B0UX77|ensembl:ENSP00000365175|ensembl:ENSP00000365201|ensembl:ENSP00000372947|ensembl:ENSP00000372956|ensembl:ENSP00000387477|ensembl:ENSP00000387910|ensembl:ENSP00000396812|ensembl:ENSP00000400540|ensembl:ENSP00000404619|ensembl:ENSP00000408226|ensembl:ENSP00000409444|ensembl:ENSP00000413977|ensembl:ENSP00000415182|ensembl:ENSP00000415363 psi-mi:tdrd3_human(display_long)|uniprotkb:TDRD3(gene name)|psi-mi:TDRD3(display_short) psi-mi:prc2a_human(display_long)|uniprotkb:HLA-B-associated transcript 2(gene name synonym)|uniprotkb:PRRC2A(gene name)|psi-mi:PRRC2A(display_short)|uniprotkb:G2(gene name synonym)|uniprotkb:Protein G2(gene name synonym)|uniprotkb:BAT2(gene name synonym)|uniprotkb:Large proline-rich protein BAT2(gene name synonym)|uniprotkb:Proline-rich and coiled-coil-containing protein 2A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485785|imex:IM-26985-369 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000083544(gene)|ensembl:ENST00000196169(transcript)|ensembl:ENST00000377894(transcript)|ensembl:ENST00000648252(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0035064"(methylated histone binding)|interpro:IPR002999(Tudor)|interpro:IPR009060(UBA-like)|interpro:IPR013894(Region of unknown function DUF1767)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR041915|interpro:IPR042470|mint:Q9H7E2|rcsb pdb:1WJI|rcsb pdb:2LTO|rcsb pdb:3PMT|rcsb pdb:3PNW|rcsb pdb:3S6W|rcsb pdb:5GVD|rcsb pdb:5GVE|rcsb pdb:5YJ8|rcsb pdb:6V9T|refseq:NP_001139542.1|refseq:NP_001139543.1|refseq:NP_110421.1|refseq:XP_016876266.1|dip:DIP-61935N refseq:NP_542417.2|refseq:NP_004629.3|ensembl:ENSP00000372956|ensembl:ENSP00000404619|ensembl:ENSP00000415182|ensembl:ENSP00000415363|ensembl:ENSP00000387910|ensembl:ENSP00000413977|ensembl:ENSP00000408226|ensembl:ENSP00000409444|ensembl:ENSP00000400540|ensembl:ENSP00000387477|ensembl:ENSP00000396812|ensembl:ENSP00000365175|ensembl:ENSP00000365201|ensembl:ENSP00000372947|ensembl:ENSG00000204469(gene)|ensembl:ENSG00000206427(gene)|ensembl:ENSG00000225164(gene)|ensembl:ENSG00000225748(gene)|ensembl:ENSG00000226618(gene)|ensembl:ENSG00000231370(gene)|ensembl:ENSG00000231825(gene)|ensembl:ENST00000376007(transcript)|ensembl:ENST00000376033(transcript)|ensembl:ENST00000383455(transcript)|ensembl:ENST00000383464(transcript)|ensembl:ENST00000414956(transcript)|ensembl:ENST00000416335(transcript)|ensembl:ENST00000422962(transcript)|ensembl:ENST00000428775(transcript)|ensembl:ENST00000430737(transcript)|ensembl:ENST00000432252(transcript)|ensembl:ENST00000435971(transcript)|ensembl:ENST00000439762(transcript)|ensembl:ENST00000454306(transcript)|ensembl:ENST00000458561(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR009738(BAT2, N-terminal)|interpro:IPR033184|mint:P48634 - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Fao3X109d50ZnSif4TMnx/seheA9606 rogid:6XZhA7FHJ4ckoWPf1yI/OnaNwjo9606 rigid:EmRrCMEXsF0tXI9sKW2WH/hwV7U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H7E2 uniprotkb:Q13043 intact:EBI-3938232|uniprotkb:Q6P992|uniprotkb:B2MWP9|uniprotkb:Q53XA6|ensembl:ENSP00000196169|ensembl:ENSP00000367126|ensembl:ENSP00000498191 intact:EBI-367376|uniprotkb:Q15802|uniprotkb:Q4G156|ensembl:ENSP00000361892|uniprotkb:Q5H982|uniprotkb:Q6PD60|uniprotkb:Q9BR32|uniprotkb:Q9NTZ4|uniprotkb:B2RCR8 psi-mi:tdrd3_human(display_long)|uniprotkb:TDRD3(gene name)|psi-mi:TDRD3(display_short) psi-mi:stk4_human(display_long)|uniprotkb:STK4(gene name)|psi-mi:STK4(display_short)|uniprotkb:MST1(gene name synonym)|uniprotkb:STE20-like kinase MST1(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase Krs-2(gene name synonym)|uniprotkb:KRS2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485785|imex:IM-26985-369 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000083544(gene)|ensembl:ENST00000196169(transcript)|ensembl:ENST00000377894(transcript)|ensembl:ENST00000648252(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0035064"(methylated histone binding)|interpro:IPR002999(Tudor)|interpro:IPR009060(UBA-like)|interpro:IPR013894(Region of unknown function DUF1767)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR041915|interpro:IPR042470|mint:Q9H7E2|rcsb pdb:1WJI|rcsb pdb:2LTO|rcsb pdb:3PMT|rcsb pdb:3PNW|rcsb pdb:3S6W|rcsb pdb:5GVD|rcsb pdb:5GVE|rcsb pdb:5YJ8|rcsb pdb:6V9T|refseq:NP_001139542.1|refseq:NP_001139543.1|refseq:NP_110421.1|refseq:XP_016876266.1|dip:DIP-61935N ensembl:ENSG00000101109(gene)|ensembl:ENST00000372806(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001841"(neural tube formation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003157"(endocardium development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|refseq:NP_006273.1|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016604"(nuclear body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0035329"(hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|refseq:XP_005260590.1|go:"GO:0060800"(regulation of cell differentiation involved in embryonic placenta development)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902043"(positive regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011524(SARAH)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024205|interpro:IPR036674|mint:Q13043|rcsb pdb:2JO8|rcsb pdb:3COM|rcsb pdb:4NR2|rcsb pdb:4OH8|rcsb pdb:5TWG|rcsb pdb:5TWH|rcsb pdb:6YAT|reactome:R-HSA-2028269|go:"GO:0060706"(cell differentiation involved in embryonic placenta development)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0046621"(negative regulation of organ growth)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051262"(protein tetramerization)|go:"GO:0060215"(primitive hemopoiesis)|dip:DIP-32491N - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Fao3X109d50ZnSif4TMnx/seheA9606 rogid:Z/Uf9T1T/jGvNFWfAkpSf5cQSWY9606 rigid:EmRrCMEXsF0tXI9sKW2WH/hwV7U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H7E2 uniprotkb:P06454 intact:EBI-3938232|uniprotkb:Q6P992|uniprotkb:B2MWP9|uniprotkb:Q53XA6|ensembl:ENSP00000196169|ensembl:ENSP00000367126|ensembl:ENSP00000498191 intact:EBI-2682091|uniprotkb:Q15249|uniprotkb:Q15592|ensembl:ENSP00000344547 psi-mi:tdrd3_human(display_long)|uniprotkb:TDRD3(gene name)|psi-mi:TDRD3(display_short) psi-mi:ptma_human(display_long)|uniprotkb:TMSA(gene name synonym)|uniprotkb:PTMA(gene name)|psi-mi:PTMA(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485785|imex:IM-26985-369 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000083544(gene)|ensembl:ENST00000196169(transcript)|ensembl:ENST00000377894(transcript)|ensembl:ENST00000648252(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0035064"(methylated histone binding)|interpro:IPR002999(Tudor)|interpro:IPR009060(UBA-like)|interpro:IPR013894(Region of unknown function DUF1767)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR041915|interpro:IPR042470|mint:Q9H7E2|rcsb pdb:1WJI|rcsb pdb:2LTO|rcsb pdb:3PMT|rcsb pdb:3PNW|rcsb pdb:3S6W|rcsb pdb:5GVD|rcsb pdb:5GVE|rcsb pdb:5YJ8|rcsb pdb:6V9T|refseq:NP_001139542.1|refseq:NP_001139543.1|refseq:NP_110421.1|refseq:XP_016876266.1|dip:DIP-61935N refseq:NP_001092755.1|refseq:NP_002814.3|ensembl:ENSG00000187514(gene)|ensembl:ENST00000341369(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR004931(Prothymosin/parathymosin)|mint:P06454|rcsb pdb:2L9I|rcsb pdb:2MNQ|dip:DIP-40743N - - comment:"author score: 34" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Fao3X109d50ZnSif4TMnx/seheA9606 rogid:scRCSTJyl5e12uNhBR+L4CKQ6Ac9606 rigid:EmRrCMEXsF0tXI9sKW2WH/hwV7U false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NAT2 uniprotkb:P23588 intact:EBI-5453826|uniprotkb:A1L4G5|uniprotkb:B7ZLV0|uniprotkb:Q5EBN4|uniprotkb:Q5VTV0|uniprotkb:Q6ZSK2|intact:EBI-28969003|ensembl:ENSP00000294848|ensembl:ENSP00000356586 intact:EBI-970310|ensembl:ENSP00000262056|uniprotkb:Q4G0E3|uniprotkb:Q53HQ2|uniprotkb:Q6GPH5|uniprotkb:Q6IB46|uniprotkb:Q8WYK5|uniprotkb:B4DS13 psi-mi:tdrd5_human(display_long)|uniprotkb:TDRD5(gene name)|psi-mi:TDRD5(display_short)|uniprotkb:TUDOR3(gene name synonym) psi-mi:if4b_human(display_long)|uniprotkb:EIF4B(gene name)|psi-mi:EIF4B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485818|imex:IM-26985-371 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000294848|ensembl:ENSP00000356586|ensembl:ENST00000444136|ensembl:ENSP00000406052|refseq:NP_001186014.1|refseq:NP_001186018.1|refseq:NP_001186020.1|refseq:NP_001186021.1|refseq:NP_775804.2|refseq:XP_005244991.1|refseq:XP_005244992.1|refseq:XP_016855962.1|ensembl:ENSG00000162782(gene)|ensembl:ENST00000294848(transcript)|ensembl:ENST00000367614(transcript)|go:"GO:0007286"(spermatid development)|go:"GO:0030719"(P granule organization)|go:"GO:0033391"(chromatoid body)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0071546"(pi-body)|interpro:IPR002999(Tudor)|interpro:IPR025605|interpro:IPR035437|interpro:IPR037982|interpro:IPR041966|mint:Q8NAT2|rcsb pdb:3S93 ensembl:ENSG00000063046(gene)|ensembl:ENST00000262056(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0030425"(dendrite)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034057"(RNA strand-exchange activity)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0097010"(eukaryotic translation initiation factor 4F complex assembly)|go:"GO:0098794"(postsynapse)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033107|interpro:IPR035979|mint:P23588|rcsb pdb:1WI8|rcsb pdb:2J76|rcsb pdb:6FEC|reactome:R-HSA-156827|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_001408.2|refseq:NP_001317583.1 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:E22w/53IvcGdOqwmO/oSzzQowdU9606 rogid:6QlRkSj6suC5apkUxdZhOq+OMBc9606 rigid:siOcD6rkjXbbDrTiTWyDGTPJaNg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NAT2 uniprotkb:Q13242 intact:EBI-5453826|uniprotkb:A1L4G5|uniprotkb:B7ZLV0|uniprotkb:Q5EBN4|uniprotkb:Q5VTV0|uniprotkb:Q6ZSK2|intact:EBI-28969003|ensembl:ENSP00000294848|ensembl:ENSP00000356586 intact:EBI-2949710|ensembl:ENSP00000229390|uniprotkb:Q52LD1 psi-mi:tdrd5_human(display_long)|uniprotkb:TDRD5(gene name)|psi-mi:TDRD5(display_short)|uniprotkb:TUDOR3(gene name synonym) psi-mi:srsf9_human(display_long)|uniprotkb:SRSF9(gene name)|psi-mi:SRSF9(display_short)|uniprotkb:SFRS9(gene name synonym)|uniprotkb:SRP30C(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SRp30C(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485818|imex:IM-26985-371 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000294848|ensembl:ENSP00000356586|ensembl:ENST00000444136|ensembl:ENSP00000406052|refseq:NP_001186014.1|refseq:NP_001186018.1|refseq:NP_001186020.1|refseq:NP_001186021.1|refseq:NP_775804.2|refseq:XP_005244991.1|refseq:XP_005244992.1|refseq:XP_016855962.1|ensembl:ENSG00000162782(gene)|ensembl:ENST00000294848(transcript)|ensembl:ENST00000367614(transcript)|go:"GO:0007286"(spermatid development)|go:"GO:0030719"(P granule organization)|go:"GO:0033391"(chromatoid body)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0071546"(pi-body)|interpro:IPR002999(Tudor)|interpro:IPR025605|interpro:IPR035437|interpro:IPR037982|interpro:IPR041966|mint:Q8NAT2|rcsb pdb:3S93 go:"GO:0006397"(mRNA processing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043279"(response to alkaloid)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|go:"GO:0006376"(mRNA splice site selection)|interpro:IPR034503|interpro:IPR034995|interpro:IPR035979|mint:Q13242|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|ensembl:ENSG00000111786(gene)|ensembl:ENST00000229390(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|refseq:NP_003760.1|dip:DIP-40741N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:E22w/53IvcGdOqwmO/oSzzQowdU9606 rogid:9x6TWFk1zN1YodjXBiwi/MtNJe49606 rigid:siOcD6rkjXbbDrTiTWyDGTPJaNg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NAT2 uniprotkb:P0CG47 intact:EBI-5453826|uniprotkb:A1L4G5|uniprotkb:B7ZLV0|uniprotkb:Q5EBN4|uniprotkb:Q5VTV0|uniprotkb:Q6ZSK2|intact:EBI-28969003|ensembl:ENSP00000294848|ensembl:ENSP00000356586 intact:EBI-413034|uniprotkb:P02248|uniprotkb:P02249|uniprotkb:P02250|uniprotkb:Q29120|uniprotkb:Q6LBL4|uniprotkb:Q6LDU5|uniprotkb:Q8WYN8|uniprotkb:Q91887|uniprotkb:Q91888|uniprotkb:Q9BWD6|uniprotkb:Q9BX98|uniprotkb:Q9UEF2|uniprotkb:Q9UEG1|uniprotkb:Q9UEK8|uniprotkb:Q9UPK7|uniprotkb:P62988|ensembl:ENSP00000304697|ensembl:ENSP00000379178|ensembl:ENSP00000379180|ensembl:ENSP00000478771 psi-mi:tdrd5_human(display_long)|uniprotkb:TDRD5(gene name)|psi-mi:TDRD5(display_short)|uniprotkb:TUDOR3(gene name synonym) psi-mi:ubb_human(display_long)|uniprotkb:UBB(gene name)|psi-mi:UBB(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485818|imex:IM-26985-371 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000294848|ensembl:ENSP00000356586|ensembl:ENST00000444136|ensembl:ENSP00000406052|refseq:NP_001186014.1|refseq:NP_001186018.1|refseq:NP_001186020.1|refseq:NP_001186021.1|refseq:NP_775804.2|refseq:XP_005244991.1|refseq:XP_005244992.1|refseq:XP_016855962.1|ensembl:ENSG00000162782(gene)|ensembl:ENST00000294848(transcript)|ensembl:ENST00000367614(transcript)|go:"GO:0007286"(spermatid development)|go:"GO:0030719"(P granule organization)|go:"GO:0033391"(chromatoid body)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0071546"(pi-body)|interpro:IPR002999(Tudor)|interpro:IPR025605|interpro:IPR035437|interpro:IPR037982|interpro:IPR041966|mint:Q8NAT2|rcsb pdb:3S93 refseq:NP_061828.1|refseq:NP_001268645.1|refseq:NP_001268646.1|refseq:NP_001268647.1|refseq:NP_001268648.1|refseq:NP_001268649.1|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|mint:P0CG47|go:"GO:0047497"(mitochondrion transport along microtubule)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060613"(fat pad development)|rcsb pdb:2KHW|rcsb pdb:2MBB|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:2MRO|go:"GO:0072520"(seminiferous tubule development)|go:"GO:0097009"(energy homeostasis)|rcsb pdb:2MSG|go:"GO:1901214"(regulation of neuron death)|rcsb pdb:2N13|rcsb pdb:4UEL|rcsb pdb:4UF6|rcsb pdb:4WHV|rcsb pdb:4WLR|rcsb pdb:4WUR|rcsb pdb:4XOF|rcsb pdb:4ZFR|rcsb pdb:4ZFT|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902527"(positive regulation of protein monoubiquitination)|rcsb pdb:4ZPZ|rcsb pdb:4ZUX|rcsb pdb:5BNB|rcsb pdb:5CAW|rcsb pdb:5CRA|rcsb pdb:5CVM|rcsb pdb:5CVN|rcsb pdb:5CVO|interpro:IPR000626(Ubiquitin)|rcsb pdb:5D0K|rcsb pdb:5D0M|rcsb pdb:5DFL|rcsb pdb:5DK8|rcsb pdb:5E6J|rcsb pdb:5EDV|rcsb pdb:5EMZ|rcsb pdb:5EYA|rcsb pdb:5GJQ|rcsb pdb:5GO7|rcsb pdb:5GO8|rcsb pdb:5GOB|rcsb pdb:5GOC|rcsb pdb:5GOD|rcsb pdb:5GOG|rcsb pdb:5GOH|rcsb pdb:5GOI|rcsb pdb:5GOJ|rcsb pdb:5GOK|rcsb pdb:5H7S|rcsb pdb:5IBK|rcsb pdb:5IFR|rcsb pdb:5JBY|rcsb pdb:5JG6|rcsb pdb:5JP3|rcsb pdb:5JTJ|rcsb pdb:5JTV|rcsb pdb:5K9P|rcsb pdb:5KGF|rcsb pdb:5KHY|rcsb pdb:5KYC|rcsb pdb:5KYD|rcsb pdb:5KYE|rcsb pdb:5KYF|rcsb pdb:5L8H|rcsb pdb:5L8W|rcsb pdb:5L9T|rcsb pdb:5LN1|rcsb pdb:5LRV|rcsb pdb:5LRW|rcsb pdb:5LRX|rcsb pdb:5M93|rcsb pdb:5MNJ|rcsb pdb:5N2W|rcsb pdb:5N38|rcsb pdb:5NL5|rcsb pdb:5NLJ|rcsb pdb:5NVG|rcsb pdb:5O44|rcsb pdb:5O6T|rcsb pdb:5OHK|rcsb pdb:5OHL|rcsb pdb:5OHN|rcsb pdb:5OHP|rcsb pdb:5TOF|rcsb pdb:5TOG|rcsb pdb:5TUT|rcsb pdb:5TXK|rcsb pdb:5UJL|rcsb pdb:5UJN|rcsb pdb:5ULF|rcsb pdb:5ULH|rcsb pdb:5ULK|rcsb pdb:5V1Y|rcsb pdb:5V1Z|rcsb pdb:5VEY|rcsb pdb:5VF0|rcsb pdb:5VNZ|rcsb pdb:5VO0|rcsb pdb:5VZM|rcsb pdb:5VZW|rcsb pdb:5W46|rcsb pdb:5WFI|rcsb pdb:5X3M|rcsb pdb:5X3N|rcsb pdb:5X3O|rcsb pdb:5XBO|rcsb pdb:5XDP|rcsb pdb:5XK4|rcsb pdb:5XK5|rcsb pdb:5XPK|rcsb pdb:5YDR|rcsb pdb:5YIJ|rcsb pdb:5YIK|rcsb pdb:5YMY|rcsb pdb:5YT6|rcsb pdb:5ZBU|rcsb pdb:5ZD0|rcsb pdb:6ASR|rcsb pdb:6BVA|rcsb pdb:6BYH|rcsb pdb:6C16|rcsb pdb:6CP2|rcsb pdb:6DGF|rcsb pdb:6EI1|rcsb pdb:6FDK|rcsb pdb:6FGE|rcsb pdb:6FTX|rcsb pdb:6FX4|rcsb pdb:6FYH|rcsb pdb:6GLC|rcsb pdb:6GZS|rcsb pdb:6H4H|rcsb pdb:6HEI|rcsb pdb:6HEK|rcsb pdb:6IF1|rcsb pdb:6ISU|rcsb pdb:6JB6|rcsb pdb:6JB7|rcsb pdb:6JMA|rcsb pdb:6K4I|rcsb pdb:6K9P|rcsb pdb:6KOW|rcsb pdb:6KOX|rcsb pdb:6LP2|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6N13|rcsb pdb:6NJ9|rcsb pdb:6NJG|rcsb pdb:6O96|rcsb pdb:6OAM|rcsb pdb:6PGV|rcsb pdb:6PZV|rcsb pdb:6QF8|rcsb pdb:6QK9|rcsb pdb:6QML|rcsb pdb:6TBM|rcsb pdb:6UH5|rcsb pdb:6XAA|rcsb pdb:7AY2|rcsb pdb:7BBD|rcsb pdb:7CAP|rcsb pdb:7JMS|rcsb pdb:7LYC|reactome:R-HSA-110312|reactome:R-HSA-110314|reactome:R-HSA-110320|reactome:R-HSA-1169091|reactome:R-HSA-1169408|reactome:R-HSA-1234176|reactome:R-HSA-1236382|reactome:R-HSA-1236974|reactome:R-HSA-1253288|reactome:R-HSA-1295596|reactome:R-HSA-1358803|reactome:R-HSA-162588|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-168928|reactome:R-HSA-174048|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174184|reactome:R-HSA-174490|reactome:R-HSA-175474|reactome:R-HSA-179409|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-182971|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-201681|reactome:R-HSA-202424|reactome:R-HSA-205043|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-211733|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2173788|reactome:R-HSA-2173791|reactome:R-HSA-174178|reactome:R-HSA-2173795|reactome:R-HSA-2173796|reactome:R-HSA-2467813|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559585|reactome:R-HSA-2565942|reactome:R-HSA-2644606|reactome:R-HSA-2672351|reactome:R-HSA-2691232|reactome:R-HSA-2871837|reactome:R-HSA-2894862|reactome:R-HSA-2979096|reactome:R-HSA-3134975|reactome:R-HSA-3322077|reactome:R-HSA-349425|reactome:R-HSA-3769402|reactome:R-HSA-3785653|reactome:R-HSA-382556|reactome:R-HSA-400253|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-4641263|reactome:R-HSA-5205685|reactome:R-HSA-532668|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655862|reactome:R-HSA-5656121|reactome:R-HSA-5656169|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5675221|reactome:R-HSA-5675482|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5684264|reactome:R-HSA-5685942|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689877|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5689901|reactome:R-HSA-5693565|reactome:R-HSA-5693607|reactome:R-HSA-5696394|reactome:R-HSA-5696395|reactome:R-HSA-5696397|reactome:R-HSA-5696400|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210|reactome:R-HSA-6783310|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804760|reactome:R-HSA-6807004|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69231|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8849469|reactome:R-HSA-983168|reactome:R-HSA-8852276|reactome:R-HSA-8941858|reactome:R-HSA-8854050|reactome:R-HSA-8856825|reactome:R-HSA-8948747|reactome:R-HSA-8948751|reactome:R-HSA-8856828|reactome:R-HSA-8951664|reactome:R-HSA-8863795|reactome:R-HSA-8866652|reactome:R-HSA-8866654|reactome:R-HSA-8875360|reactome:R-HSA-8876493|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-901032|reactome:R-HSA-9010553|reactome:R-HSA-9013507|reactome:R-HSA-9013973|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-9033241|reactome:R-HSA-912631|reactome:R-HSA-917729|reactome:R-HSA-917937|reactome:R-HSA-936440|reactome:R-HSA-936964|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9604323|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9636383|reactome:R-HSA-9637628|reactome:R-HSA-9645460|reactome:R-HSA-9646399|reactome:R-HSA-9648002|reactome:R-HSA-9664873|reactome:R-HSA-9683683|reactome:R-HSA-9694493|reactome:R-HSA-9705462|reactome:R-HSA-9706369|reactome:R-HSA-9706377|reactome:R-HSA-9708530|reactome:R-HSA-975110|reactome:R-HSA-975144|reactome:R-HSA-975163|reactome:R-HSA-977225|ensembl:ENSG00000170315(gene)|ensembl:ENST00000302182(transcript)|ensembl:ENST00000395837(transcript)|ensembl:ENST00000395839(transcript)|ensembl:ENST00000614404(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007141"(male meiosis I)|go:"GO:0007144"(female meiosis I)|go:"GO:0008585"(female gonad development)|go:"GO:0010008"(endosome membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019941"(modification-dependent protein catabolic process)|go:"GO:0021888"(hypothalamus gonadotrophin-releasing hormone neuron development)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031386"(protein tag)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body) - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:E22w/53IvcGdOqwmO/oSzzQowdU9606 rogid:X2Y1hzv2uGZd9FObQD2Qq3SECRo9606 rigid:siOcD6rkjXbbDrTiTWyDGTPJaNg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NAT2 uniprotkb:P68363 intact:EBI-5453826|uniprotkb:A1L4G5|uniprotkb:B7ZLV0|uniprotkb:Q5EBN4|uniprotkb:Q5VTV0|uniprotkb:Q6ZSK2|intact:EBI-28969003|ensembl:ENSP00000294848|ensembl:ENSP00000356586 intact:EBI-487083|intact:EBI-1384226|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:Q27I68|ensembl:ENSP00000336799|uniprotkb:Q8WU19 psi-mi:tdrd5_human(display_long)|uniprotkb:TDRD5(gene name)|psi-mi:TDRD5(display_short)|uniprotkb:TUDOR3(gene name synonym) psi-mi:tba1b_human(display_long)|uniprotkb:TUBA1B(gene name)|psi-mi:TUBA1B(display_short)|uniprotkb:Tubulin alpha-ubiquitous chain(gene name synonym)|uniprotkb:Alpha-tubulin ubiquitous(gene name synonym)|uniprotkb:Tubulin K-alpha-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485818|imex:IM-26985-371 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000294848|ensembl:ENSP00000356586|ensembl:ENST00000444136|ensembl:ENSP00000406052|refseq:NP_001186014.1|refseq:NP_001186018.1|refseq:NP_001186020.1|refseq:NP_001186021.1|refseq:NP_775804.2|refseq:XP_005244991.1|refseq:XP_005244992.1|refseq:XP_016855962.1|ensembl:ENSG00000162782(gene)|ensembl:ENST00000294848(transcript)|ensembl:ENST00000367614(transcript)|go:"GO:0007286"(spermatid development)|go:"GO:0030719"(P granule organization)|go:"GO:0033391"(chromatoid body)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0071546"(pi-body)|interpro:IPR002999(Tudor)|interpro:IPR025605|interpro:IPR035437|interpro:IPR037982|interpro:IPR041966|mint:Q8NAT2|rcsb pdb:3S93 refseq:NP_006073.2|ensembl:ENSG00000123416(gene)|ensembl:ENST00000336023(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-983189|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|go:"GO:0045121"(membrane raft)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68363|rcsb pdb:2E4H|rcsb pdb:5IJ0|rcsb pdb:5IJ9|rcsb pdb:5N5N|rcsb pdb:6E7B|rcsb pdb:6E7C|rcsb pdb:6I2I|go:"GO:0051301"(cell division)|rcsb pdb:6J4V|rcsb pdb:6J8O|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|rcsb pdb:6S8L|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9013407|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-2132295|reactome:R-HSA-9668328 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:E22w/53IvcGdOqwmO/oSzzQowdU9606 rogid:D4YpuLCXl/S+53qV7P7sF81aARY9606 rigid:siOcD6rkjXbbDrTiTWyDGTPJaNg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NAT2 uniprotkb:P35030 intact:EBI-5453826|uniprotkb:A1L4G5|uniprotkb:B7ZLV0|uniprotkb:Q5EBN4|uniprotkb:Q5VTV0|uniprotkb:Q6ZSK2|intact:EBI-28969003|ensembl:ENSP00000294848|ensembl:ENSP00000356586 intact:EBI-1221209|uniprotkb:Q5VXV0|intact:EBI-2825937|uniprotkb:A8CED3|uniprotkb:F8W7P3|uniprotkb:Q6ISJ4|uniprotkb:P15951|uniprotkb:Q15665|uniprotkb:Q9UQV3|uniprotkb:A9Z1Y4|uniprotkb:E7ES07|uniprotkb:A8CED1 psi-mi:tdrd5_human(display_long)|uniprotkb:TDRD5(gene name)|psi-mi:TDRD5(display_short)|uniprotkb:TUDOR3(gene name synonym) psi-mi:try3_human(display_long)|uniprotkb:PRSS3(gene name)|psi-mi:PRSS3(display_short)|uniprotkb:PRSS4(gene name synonym)|uniprotkb:TRY3(gene name synonym)|uniprotkb:TRY4(gene name synonym)|uniprotkb:Trypsin III(gene name synonym)|uniprotkb:Brain trypsinogen(gene name synonym)|uniprotkb:Mesotrypsinogen(gene name synonym)|uniprotkb:Trypsin IV(gene name synonym)|uniprotkb:Serine protease 3(gene name synonym)|uniprotkb:Serine protease 4(gene name synonym)|uniprotkb:Mesotrypsin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485818|imex:IM-26985-371 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000294848|ensembl:ENSP00000356586|ensembl:ENST00000444136|ensembl:ENSP00000406052|refseq:NP_001186014.1|refseq:NP_001186018.1|refseq:NP_001186020.1|refseq:NP_001186021.1|refseq:NP_775804.2|refseq:XP_005244991.1|refseq:XP_005244992.1|refseq:XP_016855962.1|ensembl:ENSG00000162782(gene)|ensembl:ENST00000294848(transcript)|ensembl:ENST00000367614(transcript)|go:"GO:0007286"(spermatid development)|go:"GO:0030719"(P granule organization)|go:"GO:0033391"(chromatoid body)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0071546"(pi-body)|interpro:IPR002999(Tudor)|interpro:IPR025605|interpro:IPR035437|interpro:IPR037982|interpro:IPR041966|mint:Q8NAT2|rcsb pdb:3S93 refseq:NP_002762.2|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR018114|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|refseq:NP_001184026.2|refseq:NP_031369.2|refseq:NP_001184027.1|mint:P35030|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0007586"(digestion)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0019730"(antimicrobial humoral response)|go:"GO:0031638"(zymogen activation)|go:"GO:0043542"(endothelial cell migration)|go:"GO:1904724"(tertiary granule lumen)|rcsb pdb:1H4W|rcsb pdb:2R9P|rcsb pdb:3L33|rcsb pdb:3L3T|rcsb pdb:3P92|rcsb pdb:3P95|rcsb pdb:4DG4|rcsb pdb:4U30|rcsb pdb:4U32|rcsb pdb:5C67|rcsb pdb:5JBT|rcsb pdb:5TP0|rcsb pdb:6BX8|rcsb pdb:6GFI|reactome:R-HSA-1462054|reactome:R-HSA-196741|reactome:R-HSA-6798695|reactome:R-HSA-6803157|interpro:IPR043504 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:E22w/53IvcGdOqwmO/oSzzQowdU9606 rogid:AEfz7orXeNoasizB5N76AkF4WMk9606 rigid:siOcD6rkjXbbDrTiTWyDGTPJaNg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NAT2 uniprotkb:Q01469 intact:EBI-5453826|uniprotkb:A1L4G5|uniprotkb:B7ZLV0|uniprotkb:Q5EBN4|uniprotkb:Q5VTV0|uniprotkb:Q6ZSK2|intact:EBI-28969003|ensembl:ENSP00000294848|ensembl:ENSP00000356586 intact:EBI-1054073|uniprotkb:B2R4K0|ensembl:ENSP00000297258 psi-mi:tdrd5_human(display_long)|uniprotkb:TDRD5(gene name)|psi-mi:TDRD5(display_short)|uniprotkb:TUDOR3(gene name synonym) psi-mi:fabp5_human(display_long)|uniprotkb:Epidermal-type fatty acid-binding protein(gene name synonym)|uniprotkb:Psoriasis-associated fatty acid-binding protein homolog(gene name synonym)|uniprotkb:FABP5(gene name)|psi-mi:FABP5(display_short)|uniprotkb:Fatty acid-binding protein, epidermal(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485818|imex:IM-26985-371 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000294848|ensembl:ENSP00000356586|ensembl:ENST00000444136|ensembl:ENSP00000406052|refseq:NP_001186014.1|refseq:NP_001186018.1|refseq:NP_001186020.1|refseq:NP_001186021.1|refseq:NP_775804.2|refseq:XP_005244991.1|refseq:XP_005244992.1|refseq:XP_016855962.1|ensembl:ENSG00000162782(gene)|ensembl:ENST00000294848(transcript)|ensembl:ENST00000367614(transcript)|go:"GO:0007286"(spermatid development)|go:"GO:0030719"(P granule organization)|go:"GO:0033391"(chromatoid body)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0071546"(pi-body)|interpro:IPR002999(Tudor)|interpro:IPR025605|interpro:IPR035437|interpro:IPR037982|interpro:IPR041966|mint:Q8NAT2|rcsb pdb:3S93 refseq:NP_001435.1|ensembl:ENSG00000164687(gene)|ensembl:ENST00000297258(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0008289"(lipid binding)|go:"GO:0008544"(epidermis development)|go:"GO:0010829"(negative regulation of glucose transmembrane transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031392"(regulation of prostaglandin biosynthetic process)|go:"GO:0035360"(positive regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099178"(regulation of retrograde trans-synaptic signaling by endocanabinoid)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990379"(lipid transport across blood-brain barrier)|interpro:IPR000463(Cytosolic fatty-acid binding)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR012674(Calycin)|interpro:IPR031259|mint:Q01469|rcsb pdb:1B56|rcsb pdb:1JJJ|rcsb pdb:4AZM|rcsb pdb:4AZR|rcsb pdb:4LKP|rcsb pdb:4LKT|rcsb pdb:5HZ5|rcsb pdb:5UR9|reactome:R-HSA-163560|reactome:R-HSA-5362517|reactome:R-HSA-6798695 - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:E22w/53IvcGdOqwmO/oSzzQowdU9606 rogid:vxp81/mezHcm5oo27QOmAM8Y5dI9606 rigid:siOcD6rkjXbbDrTiTWyDGTPJaNg false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHU6 uniprotkb:Q14011 intact:EBI-624505|uniprotkb:A6NCI6|uniprotkb:Q5VV27|uniprotkb:Q96JT1|uniprotkb:Q9UFF0|uniprotkb:Q9Y2M3|uniprotkb:B4DG99|uniprotkb:B4DXF7|uniprotkb:E7EQD4|uniprotkb:B2RBX3|ensembl:ENSP00000347444 intact:EBI-538850|uniprotkb:B4E2X2|intact:EBI-10980353|uniprotkb:B3KT17|ensembl:ENSP00000322887|ensembl:ENSP00000465779|ensembl:ENSP00000466110|ensembl:ENSP00000466207|ensembl:ENSP00000468788 psi-mi:tdrd7_human(display_long)|uniprotkb:PCTAIRE2-binding protein(gene name synonym)|uniprotkb:PCTAIRE2BP(gene name synonym)|uniprotkb:TDRD7(gene name)|psi-mi:TDRD7(display_short)|uniprotkb:Tudor repeat associator with PCTAIRE-2(gene name synonym) psi-mi:cirbp_human(display_long)|uniprotkb:Glycine-rich RNA-binding protein CIRP(gene name synonym)|uniprotkb:A18 hnRNP(gene name synonym)|uniprotkb:CIRBP(gene name)|psi-mi:CIRBP(display_short)|uniprotkb:A18HNRNP(gene name synonym)|uniprotkb:CIRP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485842|imex:IM-26985-591 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001289813.1|refseq:NP_055105.2|rcsb pdb:3RCO|ensembl:ENSG00000196116(gene)|ensembl:ENST00000355295(transcript)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070306"(lens fiber cell differentiation)|interpro:IPR002999(Tudor)|interpro:IPR025605|interpro:IPR035437|interpro:IPR037978|interpro:IPR041966|mint:Q8NHU6 refseq:NP_001271.1|refseq:XP_006722700.1|refseq:NP_001287744.1|refseq:NP_001287758.1|ensembl:ENSG00000099622(gene)|ensembl:ENST00000320936(transcript)|ensembl:ENST00000585630(transcript)|ensembl:ENST00000586472(transcript)|ensembl:ENST00000588030(transcript)|ensembl:ENST00000588090(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0009409"(response to cold)|go:"GO:0009411"(response to UV)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030371"(translation repressor activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034278|interpro:IPR035979|mint:Q14011|rcsb pdb:1X5S|rcsb pdb:5TBX - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:VMaw7t5OgA2O0RRDagDVSc+vUUU9606 rogid:nm6/8k5Pw1AnoXsSw9cazJkL49U9606 rigid:wwO7y0Z00gGP9b21iZK9VhDgDa8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHU6 uniprotkb:Q9Y6H1 intact:EBI-624505|uniprotkb:A6NCI6|uniprotkb:Q5VV27|uniprotkb:Q96JT1|uniprotkb:Q9UFF0|uniprotkb:Q9Y2M3|uniprotkb:B4DG99|uniprotkb:B4DXF7|uniprotkb:E7EQD4|uniprotkb:B2RBX3|ensembl:ENSP00000347444 intact:EBI-2321769|uniprotkb:Q498C3|uniprotkb:Q6NZ50|ensembl:ENSP00000378812 psi-mi:tdrd7_human(display_long)|uniprotkb:PCTAIRE2-binding protein(gene name synonym)|uniprotkb:PCTAIRE2BP(gene name synonym)|uniprotkb:TDRD7(gene name)|psi-mi:TDRD7(display_short)|uniprotkb:Tudor repeat associator with PCTAIRE-2(gene name synonym) psi-mi:chch2_human(display_long)|uniprotkb:CHCHD2(gene name)|psi-mi:CHCHD2(display_short)|uniprotkb:C7orf17(gene name synonym)|uniprotkb:HCV NS2 trans-regulated protein(gene name synonym)|uniprotkb:Aging-associated gene 10 protein(gene name synonym)|uniprotkb:AAG10(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485842|imex:IM-26985-591 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001289813.1|refseq:NP_055105.2|rcsb pdb:3RCO|ensembl:ENSG00000196116(gene)|ensembl:ENST00000355295(transcript)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070306"(lens fiber cell differentiation)|interpro:IPR002999(Tudor)|interpro:IPR025605|interpro:IPR035437|interpro:IPR037978|interpro:IPR041966|mint:Q8NHU6 refseq:NP_057223.1|ensembl:ENSG00000106153(gene)|ensembl:ENST00000395422(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900037"(regulation of cellular response to hypoxia)|go:"GO:1905448"(positive regulation of mitochondrial ATP synthesis coupled electron transport)|interpro:IPR010625(CHCH)|mint:Q9Y6H1|reactome:R-HSA-1268020 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:VMaw7t5OgA2O0RRDagDVSc+vUUU9606 rogid:fdx3lE51+yZ1k3uwh8/LDKJC+CQ9606 rigid:wwO7y0Z00gGP9b21iZK9VhDgDa8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHU6 uniprotkb:Q9H5H4 intact:EBI-624505|uniprotkb:A6NCI6|uniprotkb:Q5VV27|uniprotkb:Q96JT1|uniprotkb:Q9UFF0|uniprotkb:Q9Y2M3|uniprotkb:B4DG99|uniprotkb:B4DXF7|uniprotkb:E7EQD4|uniprotkb:B2RBX3|ensembl:ENSP00000347444 intact:EBI-1210580|uniprotkb:Q569L7|uniprotkb:Q96CX4|ensembl:ENSP00000369777 psi-mi:tdrd7_human(display_long)|uniprotkb:PCTAIRE2-binding protein(gene name synonym)|uniprotkb:PCTAIRE2BP(gene name synonym)|uniprotkb:TDRD7(gene name)|psi-mi:TDRD7(display_short)|uniprotkb:Tudor repeat associator with PCTAIRE-2(gene name synonym) psi-mi:zn768_human(display_long)|uniprotkb:ZNF768(gene name)|psi-mi:ZNF768(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485842|imex:IM-26985-591 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001289813.1|refseq:NP_055105.2|rcsb pdb:3RCO|ensembl:ENSG00000196116(gene)|ensembl:ENST00000355295(transcript)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070306"(lens fiber cell differentiation)|interpro:IPR002999(Tudor)|interpro:IPR025605|interpro:IPR035437|interpro:IPR037978|interpro:IPR041966|mint:Q8NHU6 refseq:NP_078947.3|ensembl:ENSG00000169957(gene)|ensembl:ENST00000380412(transcript)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR000684(RNA polymerase II, heptapeptide repeat, eukaryotic)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q9H5H4 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:VMaw7t5OgA2O0RRDagDVSc+vUUU9606 rogid:kQWxrEzummMO3IQ8wdpnXWFJn1o9606 rigid:wwO7y0Z00gGP9b21iZK9VhDgDa8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8NHU6 uniprotkb:P49959 intact:EBI-624505|uniprotkb:A6NCI6|uniprotkb:Q5VV27|uniprotkb:Q96JT1|uniprotkb:Q9UFF0|uniprotkb:Q9Y2M3|uniprotkb:B4DG99|uniprotkb:B4DXF7|uniprotkb:E7EQD4|uniprotkb:B2RBX3|ensembl:ENSP00000347444 intact:EBI-396513|uniprotkb:O43475|uniprotkb:B3KTC7|ensembl:ENSP00000325863 psi-mi:tdrd7_human(display_long)|uniprotkb:PCTAIRE2-binding protein(gene name synonym)|uniprotkb:PCTAIRE2BP(gene name synonym)|uniprotkb:TDRD7(gene name)|psi-mi:TDRD7(display_short)|uniprotkb:Tudor repeat associator with PCTAIRE-2(gene name synonym) psi-mi:mre11_human(display_long)|uniprotkb:MRE11(gene name)|psi-mi:MRE11(display_short)|uniprotkb:Double-strand break repair protein MRE11A(gene name synonym)|uniprotkb:HNGS1(gene name synonym)|uniprotkb:MRE11A(gene name synonym)|uniprotkb:Meiotic recombination 11 homolog 1(gene name synonym)|uniprotkb:Meiotic recombination 11 homolog A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485842|imex:IM-26985-591 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001289813.1|refseq:NP_055105.2|rcsb pdb:3RCO|ensembl:ENSG00000196116(gene)|ensembl:ENST00000355295(transcript)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0033391"(chromatoid body)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070306"(lens fiber cell differentiation)|interpro:IPR002999(Tudor)|interpro:IPR025605|interpro:IPR035437|interpro:IPR037978|interpro:IPR041966|mint:Q8NHU6 refseq:NP_005581.2|refseq:NP_005582.1|refseq:XP_011541139.1|refseq:XP_016873261.1|dip:DIP-33238N|ensembl:ENSG00000020922(gene)|ensembl:ENST00000323929(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000019"(regulation of mitotic recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0016605"(PML body)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0097552"(mitochondrial double-strand break repair via homologous recombination)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|interpro:IPR003701(DNA repair exonuclease)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR007281(Mre11, DNA-binding)|interpro:IPR029052|interpro:IPR038487|interpro:IPR041796|mint:P49959|rcsb pdb:3T1I|reactome:R-HSA-1834949|reactome:R-HSA-2559586|reactome:R-HSA-3270619|reactome:R-HSA-5685938|reactome:R-HSA-5685939|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:VMaw7t5OgA2O0RRDagDVSc+vUUU9606 rogid:fgwgA0BcNZ9phGBaOSYjkldDgeI9606 rigid:wwO7y0Z00gGP9b21iZK9VhDgDa8 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y2W6 uniprotkb:O75223 intact:EBI-12842466|ensembl:ENSP00000357812|ensembl:ENSP00000357815|ensembl:ENSP00000357819|ensembl:ENSP00000395718|uniprotkb:D3DV24|uniprotkb:Q5SZR3|uniprotkb:Q5SZR5|uniprotkb:Q8N582|uniprotkb:Q9NYV5 intact:EBI-6912130|ensembl:ENSP00000275428|uniprotkb:B8ZZR8|uniprotkb:Q9BS37|uniprotkb:B8ZZN4|uniprotkb:B2RDN0 psi-mi:tdrkh_human(display_long)|uniprotkb:TDRKH(gene name)|psi-mi:TDRKH(display_short)|uniprotkb:TDRD2(gene name synonym)|uniprotkb:Tudor domain-containing protein 2(gene name synonym) psi-mi:ggct_human(display_long)|uniprotkb:C7orf24(gene name synonym)|uniprotkb:CRF21(gene name synonym)|uniprotkb:Cytochrome c-releasing factor 21(gene name synonym)|uniprotkb:GGCT(gene name)|psi-mi:GGCT(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485860|imex:IM-26985-69 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000182134(gene)|ensembl:ENST00000368822(transcript)|ensembl:ENST00000368824(transcript)|ensembl:ENST00000368827(transcript)|ensembl:ENST00000458431(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009566"(fertilization)|go:"GO:0030154"(cell differentiation)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0034587"(piRNA metabolic process)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0071546"(pi-body)|go:"GO:0071547"(piP-body)|interpro:IPR002999(Tudor)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR035437|interpro:IPR036612|mint:Q9Y2W6|rcsb pdb:2DIQ|rcsb pdb:3FDR|rcsb pdb:5J39|rcsb pdb:6B57|rcsb pdb:6PI7|reactome:R-HSA-5601884|refseq:NP_001077432.1|refseq:NP_001077433.1|refseq:NP_001077434.1|refseq:NP_006853.2|refseq:XP_016855611.1|refseq:XP_016855612.1|refseq:XP_016855613.1|refseq:XP_016855614.1|refseq:XP_016855615.1|refseq:XP_016855616.1|dip:DIP-59459N ensembl:ENSG00000006625(gene)|ensembl:ENST00000275428(transcript)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003839"(gamma-glutamylcyclotransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013024(Butirosin biosynthesis, BtrG-like)|interpro:IPR017939|interpro:IPR036568|mint:O75223|rcsb pdb:2I5T|rcsb pdb:2PN7|rcsb pdb:2Q53|rcsb pdb:2RBH|rcsb pdb:3CRY|reactome:R-HSA-174403|refseq:NP_001186744.1|refseq:NP_001186745.1|refseq:NP_001186746.1|refseq:NP_076956.1 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pP4akpV5Kqvd0p+5V750mkXASPg9606 rogid:OPoR51zHOj/GAUlzTuVvYmxaaxk9606 rigid:9kZDoUIgz2vr4lT+M8znR7bsvCY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y2W6 uniprotkb:Q07955 intact:EBI-12842466|ensembl:ENSP00000357812|ensembl:ENSP00000357815|ensembl:ENSP00000357819|ensembl:ENSP00000395718|uniprotkb:D3DV24|uniprotkb:Q5SZR3|uniprotkb:Q5SZR5|uniprotkb:Q8N582|uniprotkb:Q9NYV5 intact:EBI-398920|uniprotkb:Q13809|uniprotkb:B2R6Z7|uniprotkb:D3DTZ3|ensembl:ENSP00000258962 psi-mi:tdrkh_human(display_long)|uniprotkb:TDRKH(gene name)|psi-mi:TDRKH(display_short)|uniprotkb:TDRD2(gene name synonym)|uniprotkb:Tudor domain-containing protein 2(gene name synonym) psi-mi:srsf1_human(display_long)|uniprotkb:SF2(gene name synonym)|uniprotkb:SF2P33(gene name synonym)|uniprotkb:OK/SW-cl.3(orf name)|uniprotkb:SRSF1(gene name)|psi-mi:SRSF1(display_short)|uniprotkb:ASF(gene name synonym)|uniprotkb:pre-mRNA-splicing factor SF2, P33 subunit(gene name synonym)|uniprotkb:Alternative-splicing factor 1(gene name synonym)|uniprotkb:SFRS1(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485860|imex:IM-26985-69 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000182134(gene)|ensembl:ENST00000368822(transcript)|ensembl:ENST00000368824(transcript)|ensembl:ENST00000368827(transcript)|ensembl:ENST00000458431(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009566"(fertilization)|go:"GO:0030154"(cell differentiation)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0034587"(piRNA metabolic process)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0071546"(pi-body)|go:"GO:0071547"(piP-body)|interpro:IPR002999(Tudor)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR035437|interpro:IPR036612|mint:Q9Y2W6|rcsb pdb:2DIQ|rcsb pdb:3FDR|rcsb pdb:5J39|rcsb pdb:6B57|rcsb pdb:6PI7|reactome:R-HSA-5601884|refseq:NP_001077432.1|refseq:NP_001077433.1|refseq:NP_001077434.1|refseq:NP_006853.2|refseq:XP_016855611.1|refseq:XP_016855612.1|refseq:XP_016855613.1|refseq:XP_016855614.1|refseq:XP_016855615.1|refseq:XP_016855616.1|dip:DIP-59459N refseq:NP_001071634.1|refseq:NP_008855.1|dip:DIP-2155N|ensembl:ENSG00000136450(gene)|ensembl:ENST00000258962(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006397"(mRNA processing)|go:"GO:0016607"(nuclear speck)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0043422"(protein kinase B binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0051028"(mRNA transport)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:0097421"(liver regeneration)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034520|interpro:IPR035979|mint:Q07955|rcsb pdb:2M7S|rcsb pdb:2M8D|rcsb pdb:2O3D|rcsb pdb:3BEG|rcsb pdb:4C0O|rcsb pdb:6HPJ|rcsb pdb:7ABG|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-72187|reactome:R-HSA-73856|rcsb pdb:1X4A - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pP4akpV5Kqvd0p+5V750mkXASPg9606 rogid:6/IA4a3btkfSBtMH32iCe+rqZ8Y9606 rigid:9kZDoUIgz2vr4lT+M8znR7bsvCY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y2W6 uniprotkb:P25311 intact:EBI-12842466|ensembl:ENSP00000357812|ensembl:ENSP00000357815|ensembl:ENSP00000357819|ensembl:ENSP00000395718|uniprotkb:D3DV24|uniprotkb:Q5SZR3|uniprotkb:Q5SZR5|uniprotkb:Q8N582|uniprotkb:Q9NYV5 intact:EBI-2513837|ensembl:ENSP00000292401|uniprotkb:Q5XKQ4|uniprotkb:O60386|uniprotkb:Q8N4N0|uniprotkb:D6W5T8 psi-mi:tdrkh_human(display_long)|uniprotkb:TDRKH(gene name)|psi-mi:TDRKH(display_short)|uniprotkb:TDRD2(gene name synonym)|uniprotkb:Tudor domain-containing protein 2(gene name synonym) psi-mi:za2g_human(display_long)|uniprotkb:AZGP1(gene name)|psi-mi:AZGP1(display_short)|uniprotkb:ZAG(gene name synonym)|uniprotkb:ZNGP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485860|imex:IM-26985-69 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000182134(gene)|ensembl:ENST00000368822(transcript)|ensembl:ENST00000368824(transcript)|ensembl:ENST00000368827(transcript)|ensembl:ENST00000458431(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009566"(fertilization)|go:"GO:0030154"(cell differentiation)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0034587"(piRNA metabolic process)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0071546"(pi-body)|go:"GO:0071547"(piP-body)|interpro:IPR002999(Tudor)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR035437|interpro:IPR036612|mint:Q9Y2W6|rcsb pdb:2DIQ|rcsb pdb:3FDR|rcsb pdb:5J39|rcsb pdb:6B57|rcsb pdb:6PI7|reactome:R-HSA-5601884|refseq:NP_001077432.1|refseq:NP_001077433.1|refseq:NP_001077434.1|refseq:NP_006853.2|refseq:XP_016855611.1|refseq:XP_016855612.1|refseq:XP_016855613.1|refseq:XP_016855614.1|refseq:XP_016855615.1|refseq:XP_016855616.1|dip:DIP-59459N ensembl:ENSG00000160862(gene)|ensembl:ENST00000292401(transcript)|go:"GO:0001580"(detection of chemical stimulus involved in sensory perception of bitter taste)|go:"GO:0001895"(retina homeostasis)|go:"GO:0002476"(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0007155"(cell adhesion)|go:"GO:0008285"(negative regulation of cell population proliferation)|interpro:IPR036179|interpro:IPR037055|mint:P25311|rcsb pdb:1T7V|rcsb pdb:1T7W|rcsb pdb:1T7X|rcsb pdb:1T7Y|rcsb pdb:1T7Z|rcsb pdb:1T80|rcsb pdb:1ZAG|rcsb pdb:3ES6|rcsb pdb:6R2U|reactome:R-HSA-5223345|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|refseq:NP_001176.1 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pP4akpV5Kqvd0p+5V750mkXASPg9606 rogid:3Fp6qALNiZRqsI8Kh2lTQ9IMYek9606 rigid:9kZDoUIgz2vr4lT+M8znR7bsvCY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y2W6 uniprotkb:Q15233 intact:EBI-12842466|ensembl:ENSP00000357812|ensembl:ENSP00000357815|ensembl:ENSP00000357819|ensembl:ENSP00000395718|uniprotkb:D3DV24|uniprotkb:Q5SZR3|uniprotkb:Q5SZR5|uniprotkb:Q8N582|uniprotkb:Q9NYV5 intact:EBI-350527|ensembl:ENSP00000503233|uniprotkb:O00201|uniprotkb:P30807|uniprotkb:Q12786|uniprotkb:Q9BQC5|ensembl:ENSP00000276079|ensembl:ENSP00000362947|ensembl:ENSP00000406673|ensembl:ENSP00000410299|ensembl:ENSP00000415777|ensembl:ENSP00000503031|ensembl:ENSP00000504314|ensembl:ENSP00000504351|uniprotkb:D3DVV4|uniprotkb:B7Z4C2|uniprotkb:F5GYZ3 psi-mi:tdrkh_human(display_long)|uniprotkb:TDRKH(gene name)|psi-mi:TDRKH(display_short)|uniprotkb:TDRD2(gene name synonym)|uniprotkb:Tudor domain-containing protein 2(gene name synonym) psi-mi:nono_human(display_long)|uniprotkb:NONO(gene name)|psi-mi:NONO(display_short)|uniprotkb:NRB54(gene name synonym)|uniprotkb:54 kDa nuclear RNA- and DNA-binding protein(gene name synonym)|uniprotkb:"p54(nrb)"(gene name synonym)|uniprotkb:55 kDa nuclear protein(gene name synonym)|uniprotkb:NMT55(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 52 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485860|imex:IM-26985-69 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000182134(gene)|ensembl:ENST00000368822(transcript)|ensembl:ENST00000368824(transcript)|ensembl:ENST00000368827(transcript)|ensembl:ENST00000458431(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009566"(fertilization)|go:"GO:0030154"(cell differentiation)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0034587"(piRNA metabolic process)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0071546"(pi-body)|go:"GO:0071547"(piP-body)|interpro:IPR002999(Tudor)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR035437|interpro:IPR036612|mint:Q9Y2W6|rcsb pdb:2DIQ|rcsb pdb:3FDR|rcsb pdb:5J39|rcsb pdb:6B57|rcsb pdb:6PI7|reactome:R-HSA-5601884|refseq:NP_001077432.1|refseq:NP_001077433.1|refseq:NP_001077434.1|refseq:NP_006853.2|refseq:XP_016855611.1|refseq:XP_016855612.1|refseq:XP_016855613.1|refseq:XP_016855614.1|refseq:XP_016855615.1|refseq:XP_016855616.1|dip:DIP-59459N refseq:NP_001138880.1|refseq:NP_001138881.1|refseq:NP_001138882.1|refseq:NP_031389.3|ensembl:ENSG00000147140(gene)|ensembl:ENST00000276079(transcript)|ensembl:ENST00000373841(transcript)|ensembl:ENST00000420903(transcript)|ensembl:ENST00000450092(transcript)|ensembl:ENST00000454976(transcript)|ensembl:ENST00000677274(transcript)|ensembl:ENST00000677446(transcript)|ensembl:ENST00000677612(transcript)|ensembl:ENST00000678231(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0042382"(paraspeckles)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034552|interpro:IPR035979|mint:Q15233|rcsb pdb:3SDE|rcsb pdb:5IFM|rcsb pdb:6WMZ|rcsb pdb:7LRQ|dip:DIP-29951N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pP4akpV5Kqvd0p+5V750mkXASPg9606 rogid:5W3ooO4h0qh3GKO+WjDrLBhihHA9606 rigid:9kZDoUIgz2vr4lT+M8znR7bsvCY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y2W6 uniprotkb:Q15149 intact:EBI-12842466|ensembl:ENSP00000357812|ensembl:ENSP00000357815|ensembl:ENSP00000357819|ensembl:ENSP00000395718|uniprotkb:D3DV24|uniprotkb:Q5SZR3|uniprotkb:Q5SZR5|uniprotkb:Q8N582|uniprotkb:Q9NYV5 intact:EBI-297903|intact:EBI-1103289|intact:EBI-1103265|intact:EBI-1055056|uniprotkb:Q15148|uniprotkb:Q16640|ensembl:ENSP00000323856|uniprotkb:Q6S376|intact:EBI-28976159|uniprotkb:Q6S380|intact:EBI-1103313|uniprotkb:Q6S377|uniprotkb:Q6S378|uniprotkb:Q6S379|intact:EBI-1103301|intact:EBI-1103253|uniprotkb:Q6S381|uniprotkb:Q6S382|uniprotkb:Q6S383|intact:EBI-2825763 psi-mi:tdrkh_human(display_long)|uniprotkb:TDRKH(gene name)|psi-mi:TDRKH(display_short)|uniprotkb:TDRD2(gene name synonym)|uniprotkb:Tudor domain-containing protein 2(gene name synonym) psi-mi:plec_human(display_long)|uniprotkb:PLEC(gene name)|psi-mi:PLEC(display_short)|uniprotkb:Hemidesmosomal protein 1(gene name synonym)|uniprotkb:PLEC1(gene name synonym)|uniprotkb:Plectin-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485860|imex:IM-26985-69 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000182134(gene)|ensembl:ENST00000368822(transcript)|ensembl:ENST00000368824(transcript)|ensembl:ENST00000368827(transcript)|ensembl:ENST00000458431(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009566"(fertilization)|go:"GO:0030154"(cell differentiation)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0034587"(piRNA metabolic process)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0071546"(pi-body)|go:"GO:0071547"(piP-body)|interpro:IPR002999(Tudor)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR035437|interpro:IPR036612|mint:Q9Y2W6|rcsb pdb:2DIQ|rcsb pdb:3FDR|rcsb pdb:5J39|rcsb pdb:6B57|rcsb pdb:6PI7|reactome:R-HSA-5601884|refseq:NP_001077432.1|refseq:NP_001077433.1|refseq:NP_001077434.1|refseq:NP_006853.2|refseq:XP_016855611.1|refseq:XP_016855612.1|refseq:XP_016855613.1|refseq:XP_016855614.1|refseq:XP_016855615.1|refseq:XP_016855616.1|dip:DIP-59459N go:"GO:0030018"(Z disc)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032094"(response to food)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042060"(wound healing)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043114"(regulation of vascular permeability)|go:"GO:0043209"(myelin sheath)|go:"GO:0043621"(protein self-association)|go:"GO:0043933"(protein-containing complex organization)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSG00000178209(gene)|ensembl:ENST00000322810(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0002522"(leukocyte migration involved in immune response)|go:"GO:0003334"(keratinocyte development)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071464"(cellular response to hydrostatic pressure)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0120193"(tight junction organization)|go:"GO:2000689"(actomyosin contractile ring assembly actin filament organization)|go:"GO:2000983"(regulation of ATP citrate synthase activity)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR005326(Plectin/S10, N-terminal)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006997"(nucleus organization)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010467"(gene expression)|go:"GO:0010761"(fibroblast migration)|go:"GO:0010818"(T cell chemotaxis)|go:"GO:0014866"(skeletal myofibril assembly)|go:"GO:0016020"(membrane)|go:"GO:0016528"(sarcoplasm)|go:"GO:0016569"(obsolete covalent chromatin modification)|go:"GO:0019226"(transmission of nerve impulse)|interpro:IPR030269|interpro:IPR035915|interpro:IPR018159|interpro:IPR036388|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:Q15149|rcsb pdb:1MB8|rcsb pdb:2N03|rcsb pdb:2ODU|rcsb pdb:2ODV|rcsb pdb:3F7P|rcsb pdb:3PDY|rcsb pdb:3PE0|rcsb pdb:4GDO|rcsb pdb:4Q58|rcsb pdb:4Q59|rcsb pdb:5J1F|rcsb pdb:5J1G|rcsb pdb:5J1H|rcsb pdb:5J1I|reactome:R-HSA-2022090|reactome:R-HSA-264870|reactome:R-HSA-446107|ensembl:ENST00000436759|ensembl:ENSP00000388180|ensembl:ENST00000527096|ensembl:ENSP00000434583|ensembl:ENSP00000323856|ensembl:ENST00000345136|ensembl:ENSP00000344848|ensembl:ENST00000354589|ensembl:ENSP00000346602|ensembl:ENST00000354958|ensembl:ENSP00000347044|ensembl:ENST00000356346|ensembl:ENSP00000348702|ensembl:ENST00000357649|ensembl:ENSP00000350277|ensembl:ENST00000398774|ensembl:ENSP00000381756|refseq:NP_000436.2|refseq:NP_958780.1|refseq:NP_958781.1|refseq:NP_958782.1|refseq:NP_958783.1|refseq:NP_958784.1|refseq:NP_958785.1|refseq:NP_958786.1 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pP4akpV5Kqvd0p+5V750mkXASPg9606 rogid:zbctDAOOCaJUx3WBdp85v7SI0sI9606 rigid:9kZDoUIgz2vr4lT+M8znR7bsvCY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y2W6 uniprotkb:Q9HCY8 intact:EBI-12842466|ensembl:ENSP00000357812|ensembl:ENSP00000357815|ensembl:ENSP00000357819|ensembl:ENSP00000395718|uniprotkb:D3DV24|uniprotkb:Q5SZR3|uniprotkb:Q5SZR5|uniprotkb:Q8N582|uniprotkb:Q9NYV5 intact:EBI-751842|uniprotkb:Q5RHT0|ensembl:ENSP00000340463|ensembl:ENSP00000357690|ensembl:ENSP00000357691|ensembl:ENSP00000420296 psi-mi:tdrkh_human(display_long)|uniprotkb:TDRKH(gene name)|psi-mi:TDRKH(display_short)|uniprotkb:TDRD2(gene name synonym)|uniprotkb:Tudor domain-containing protein 2(gene name synonym) psi-mi:s10ae_human(display_long)|uniprotkb:S100 calcium-binding protein A14(gene name synonym)|uniprotkb:S100A14(gene name)|psi-mi:S100A14(display_short)|uniprotkb:S100A15(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485860|imex:IM-26985-69 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000182134(gene)|ensembl:ENST00000368822(transcript)|ensembl:ENST00000368824(transcript)|ensembl:ENST00000368827(transcript)|ensembl:ENST00000458431(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009566"(fertilization)|go:"GO:0030154"(cell differentiation)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0034587"(piRNA metabolic process)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0071546"(pi-body)|go:"GO:0071547"(piP-body)|interpro:IPR002999(Tudor)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR035437|interpro:IPR036612|mint:Q9Y2W6|rcsb pdb:2DIQ|rcsb pdb:3FDR|rcsb pdb:5J39|rcsb pdb:6B57|rcsb pdb:6PI7|reactome:R-HSA-5601884|refseq:NP_001077432.1|refseq:NP_001077433.1|refseq:NP_001077434.1|refseq:NP_006853.2|refseq:XP_016855611.1|refseq:XP_016855612.1|refseq:XP_016855613.1|refseq:XP_016855614.1|refseq:XP_016855615.1|refseq:XP_016855616.1|dip:DIP-59459N refseq:NP_065723.1|refseq:XP_005245419.1|refseq:XP_016857364.1|ensembl:ENSG00000189334(gene)|ensembl:ENST00000344616(transcript)|ensembl:ENST00000368701(transcript)|ensembl:ENST00000368702(transcript)|ensembl:ENST00000476873(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0006915"(apoptotic process)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0042379"(chemokine receptor binding)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071624"(positive regulation of granulocyte chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028493|mint:Q9HCY8|rcsb pdb:2M0R - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pP4akpV5Kqvd0p+5V750mkXASPg9606 rogid:8XSIQKZSb+jAmTmawRUTHjcGwb49606 rigid:9kZDoUIgz2vr4lT+M8znR7bsvCY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y2W6 uniprotkb:P63241 intact:EBI-12842466|ensembl:ENSP00000357812|ensembl:ENSP00000357815|ensembl:ENSP00000357819|ensembl:ENSP00000395718|uniprotkb:D3DV24|uniprotkb:Q5SZR3|uniprotkb:Q5SZR5|uniprotkb:Q8N582|uniprotkb:Q9NYV5 intact:EBI-373150|uniprotkb:P10159|uniprotkb:Q16182|uniprotkb:Q7L7L3|uniprotkb:Q7Z4L1|uniprotkb:Q9D0G2|uniprotkb:A8K9A0|uniprotkb:D3DTP2|ensembl:ENSP00000336776|ensembl:ENSP00000390677|ensembl:ENSP00000396073|ensembl:ENSP00000458269|ensembl:ENSP00000459196|ensembl:ENSP00000459611|ensembl:ENSP00000499855|ensembl:ENSP00000499995|ensembl:ENSP00000500414|ensembl:ENSP00000500624|ensembl:ENSP00000500717|ensembl:ENSP00000500847 psi-mi:tdrkh_human(display_long)|uniprotkb:TDRKH(gene name)|psi-mi:TDRKH(display_short)|uniprotkb:TDRD2(gene name synonym)|uniprotkb:Tudor domain-containing protein 2(gene name synonym) psi-mi:if5a1_human(display_long)|uniprotkb:EIF5A(gene name)|psi-mi:EIF5A(display_short)|uniprotkb:Eukaryotic initiation factor 5A isoform 1(gene name synonym)|uniprotkb:eIF-4D(gene name synonym)|uniprotkb:Rev-binding factor(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485860|imex:IM-26985-69 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000182134(gene)|ensembl:ENST00000368822(transcript)|ensembl:ENST00000368824(transcript)|ensembl:ENST00000368827(transcript)|ensembl:ENST00000458431(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009566"(fertilization)|go:"GO:0030154"(cell differentiation)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0034587"(piRNA metabolic process)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0071546"(pi-body)|go:"GO:0071547"(piP-body)|interpro:IPR002999(Tudor)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR035437|interpro:IPR036612|mint:Q9Y2W6|rcsb pdb:2DIQ|rcsb pdb:3FDR|rcsb pdb:5J39|rcsb pdb:6B57|rcsb pdb:6PI7|reactome:R-HSA-5601884|refseq:NP_001077432.1|refseq:NP_001077433.1|refseq:NP_001077434.1|refseq:NP_006853.2|refseq:XP_016855611.1|refseq:XP_016855612.1|refseq:XP_016855613.1|refseq:XP_016855614.1|refseq:XP_016855615.1|refseq:XP_016855616.1|dip:DIP-59459N refseq:NP_001137232.1|refseq:NP_001137233.1|refseq:NP_001137234.1|refseq:NP_001961.1|refseq:XP_005256566.1|ensembl:ENSG00000132507(gene)|ensembl:ENSG00000288145(gene)|ensembl:ENST00000336458(transcript)|ensembl:ENST00000416016(transcript)|ensembl:ENST00000419711(transcript)|ensembl:ENST00000571955(transcript)|ensembl:ENST00000573542(transcript)|ensembl:ENST00000576930(transcript)|ensembl:ENST00000672250(transcript)|ensembl:ENST00000672755(transcript)|ensembl:ENST00000673099(transcript)|ensembl:ENST00000673210(transcript)|ensembl:ENST00000673259(transcript)|ensembl:ENST00000673304(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005642"(annulate lamellae)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0043022"(ribosome binding)|go:"GO:0045901"(positive regulation of translational elongation)|go:"GO:0045905"(positive regulation of translational termination)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051028"(mRNA transport)|go:"GO:0098586"(cellular response to virus)|go:"GO:1902255"(positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|interpro:IPR001884("Eukaryotic initiation factor 5A hypusine (eIF-5A)")|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR019769|interpro:IPR020189|mint:P63241|rcsb pdb:1FH4|rcsb pdb:3CPF|rcsb pdb:5DLQ|reactome:R-HSA-204626 - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pP4akpV5Kqvd0p+5V750mkXASPg9606 rogid:/smk81DLs+XvrqXmIZpfvdHHauk9606 rigid:9kZDoUIgz2vr4lT+M8znR7bsvCY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9Y2W6 uniprotkb:P31025 intact:EBI-12842466|ensembl:ENSP00000357812|ensembl:ENSP00000357815|ensembl:ENSP00000357819|ensembl:ENSP00000395718|uniprotkb:D3DV24|uniprotkb:Q5SZR3|uniprotkb:Q5SZR5|uniprotkb:Q8N582|uniprotkb:Q9NYV5 intact:EBI-1052433|uniprotkb:Q5T8A1|ensembl:ENSP00000263598|ensembl:ENSP00000360846 psi-mi:tdrkh_human(display_long)|uniprotkb:TDRKH(gene name)|psi-mi:TDRKH(display_short)|uniprotkb:TDRD2(gene name synonym)|uniprotkb:Tudor domain-containing protein 2(gene name synonym) psi-mi:lcn1_human(display_long)|uniprotkb:Tear prealbumin(gene name synonym)|uniprotkb:Tear lipocalin(gene name synonym)|uniprotkb:LCN1(gene name)|psi-mi:LCN1(display_short)|uniprotkb:VEGP(gene name synonym)|uniprotkb:von Ebner gland protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485860|imex:IM-26985-69 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000182134(gene)|ensembl:ENST00000368822(transcript)|ensembl:ENST00000368824(transcript)|ensembl:ENST00000368827(transcript)|ensembl:ENST00000458431(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0007140"(male meiotic nuclear division)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009566"(fertilization)|go:"GO:0030154"(cell differentiation)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0034587"(piRNA metabolic process)|go:"GO:0043046"(DNA methylation involved in gamete generation)|go:"GO:0071546"(pi-body)|go:"GO:0071547"(piP-body)|interpro:IPR002999(Tudor)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR035437|interpro:IPR036612|mint:Q9Y2W6|rcsb pdb:2DIQ|rcsb pdb:3FDR|rcsb pdb:5J39|rcsb pdb:6B57|rcsb pdb:6PI7|reactome:R-HSA-5601884|refseq:NP_001077432.1|refseq:NP_001077433.1|refseq:NP_001077434.1|refseq:NP_006853.2|refseq:XP_016855611.1|refseq:XP_016855612.1|refseq:XP_016855613.1|refseq:XP_016855614.1|refseq:XP_016855615.1|refseq:XP_016855616.1|dip:DIP-59459N refseq:NP_002288.1|refseq:NP_001239547.1|refseq:NP_001239548.1|refseq:NP_001239546.1|ensembl:ENSG00000160349(gene)|ensembl:ENST00000263598(transcript)|ensembl:ENST00000371781(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031404"(chloride ion binding)|go:"GO:0036094"(small molecule binding)|go:"GO:0050896"(response to stimulus)|go:"GO:0050909"(sensory perception of taste)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR002345(Lipocalin)|interpro:IPR002450(von Ebner's gland protein/ Bos/Can allergen)|interpro:IPR012674(Calycin)|mint:P31025|rcsb pdb:1XKI|rcsb pdb:3EYC|rcsb pdb:4QAF|rcsb pdb:5T43|reactome:R-HSA-804914 - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:pP4akpV5Kqvd0p+5V750mkXASPg9606 rogid:bpcDgVZMNuh6M1hEl3b8IncbuO49606 rigid:9kZDoUIgz2vr4lT+M8znR7bsvCY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q04725 uniprotkb:P40227 intact:EBI-1176061|uniprotkb:Q8WVY0|uniprotkb:Q9Y6S0|ensembl:ENSP00000262953|uniprotkb:B4DE03|uniprotkb:E9PEV7|uniprotkb:F8WCH2 intact:EBI-356687|uniprotkb:Q3KP28|uniprotkb:Q75LP4|uniprotkb:Q96S46|ensembl:ENSP00000275603|intact:EBI-5912031|uniprotkb:A6NCD2 psi-mi:tle2_human(display_long)|uniprotkb:Enhancer of split groucho-like protein 2(gene name synonym)|uniprotkb:TLE2(gene name)|psi-mi:TLE2(display_short) psi-mi:tcpz_human(display_long)|uniprotkb:CCT6A(gene name)|psi-mi:CCT6A(display_short)|uniprotkb:CCT6(gene name synonym)|uniprotkb:CCTZ(gene name synonym)|uniprotkb:CCT-zeta-1(gene name synonym)|uniprotkb:Tcp20(gene name synonym)|uniprotkb:HTR3(gene name synonym)|uniprotkb:Acute morphine dependence-related protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485944|imex:IM-26985-215 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000065717(gene)|ensembl:ENST00000262953(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_001287775.1|refseq:NP_001138233.1|refseq:NP_001138234.1|refseq:NP_003251.2|interpro:IPR019775|interpro:IPR036322|mint:Q04725|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-3769402|reactome:R-HSA-4641265 refseq:NP_001753.1|ensembl:ENSG00000146731(gene)|ensembl:ENST00000275603(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071987"(WD40-repeat domain binding)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012722(T-complex protein 1, zeta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P40227|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|refseq:NP_001009186.1|dip:DIP-33558N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QlgGABrHV/Wi5v8Pb3SQAq+1gTU9606 rogid:kX6/rTGZbGuVLNgBW6IxdNlU46U9606 rigid:oAwFfbOzWouvcnQ+jSb8htZDG68 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q04725 uniprotkb:P78371 intact:EBI-1176061|uniprotkb:Q8WVY0|uniprotkb:Q9Y6S0|ensembl:ENSP00000262953|uniprotkb:B4DE03|uniprotkb:E9PEV7|uniprotkb:F8WCH2 intact:EBI-357407|uniprotkb:Q14D36|uniprotkb:Q6IAT3|uniprotkb:A8K402|uniprotkb:B5BTY7|uniprotkb:B7Z243|uniprotkb:B7Z7K4|uniprotkb:B7ZAT2|ensembl:ENSP00000299300 psi-mi:tle2_human(display_long)|uniprotkb:Enhancer of split groucho-like protein 2(gene name synonym)|uniprotkb:TLE2(gene name)|psi-mi:TLE2(display_short) psi-mi:tcpb_human(display_long)|uniprotkb:CCT2(gene name)|psi-mi:CCT2(display_short)|uniprotkb:99D8.1(gene name synonym)|uniprotkb:CCTB(gene name synonym)|uniprotkb:CCT-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485944|imex:IM-26985-215 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000065717(gene)|ensembl:ENST00000262953(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_001287775.1|refseq:NP_001138233.1|refseq:NP_001138234.1|refseq:NP_003251.2|interpro:IPR019775|interpro:IPR036322|mint:Q04725|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-3769402|reactome:R-HSA-4641265 refseq:NP_006422.1|refseq:NP_001185771.1|dip:DIP-38123N|ensembl:ENSG00000166226(gene)|ensembl:ENST00000299300(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051086"(chaperone mediated protein folding independent of cofactor)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012716(T-complex protein 1, beta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P78371|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422|reactome:R-HSA-6798695 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QlgGABrHV/Wi5v8Pb3SQAq+1gTU9606 rogid:YHuvdAzWVCxx1WNk1bF/4tlOxf89606 rigid:oAwFfbOzWouvcnQ+jSb8htZDG68 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q04725 uniprotkb:P49368 intact:EBI-1176061|uniprotkb:Q8WVY0|uniprotkb:Q9Y6S0|ensembl:ENSP00000262953|uniprotkb:B4DE03|uniprotkb:E9PEV7|uniprotkb:F8WCH2 intact:EBI-356673|uniprotkb:Q5SZY1|uniprotkb:Q9BR64|uniprotkb:A6NE14|ensembl:ENSP00000295688 psi-mi:tle2_human(display_long)|uniprotkb:Enhancer of split groucho-like protein 2(gene name synonym)|uniprotkb:TLE2(gene name)|psi-mi:TLE2(display_short) psi-mi:tcpg_human(display_long)|uniprotkb:CCT3(gene name)|psi-mi:CCT3(display_short)|uniprotkb:CCTG(gene name synonym)|uniprotkb:TRIC5(gene name synonym)|uniprotkb:CCT-gamma(gene name synonym)|uniprotkb:hTRiC5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485944|imex:IM-26985-215 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000065717(gene)|ensembl:ENST00000262953(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_001287775.1|refseq:NP_001138233.1|refseq:NP_001138234.1|refseq:NP_003251.2|interpro:IPR019775|interpro:IPR036322|mint:Q04725|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-3769402|reactome:R-HSA-4641265 refseq:NP_001008800.1|refseq:NP_005989.3|ensembl:ENSG00000163468(gene)|ensembl:ENST00000295688(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012719(T-complex protein 1, gamma subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P49368|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|dip:DIP-32970N - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QlgGABrHV/Wi5v8Pb3SQAq+1gTU9606 rogid:2Vh45aNIeqiAp1NHbIabV2kEYUU9606 rigid:oAwFfbOzWouvcnQ+jSb8htZDG68 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q04725 uniprotkb:P50991 intact:EBI-1176061|uniprotkb:Q8WVY0|uniprotkb:Q9Y6S0|ensembl:ENSP00000262953|uniprotkb:B4DE03|uniprotkb:E9PEV7|uniprotkb:F8WCH2 intact:EBI-356876|uniprotkb:O14870|uniprotkb:Q96C51|uniprotkb:Q53QP9|uniprotkb:B2R6I3|uniprotkb:B7Z8B1|uniprotkb:F5H5W3|ensembl:ENSP00000377958 psi-mi:tle2_human(display_long)|uniprotkb:Enhancer of split groucho-like protein 2(gene name synonym)|uniprotkb:TLE2(gene name)|psi-mi:TLE2(display_short) psi-mi:tcpd_human(display_long)|uniprotkb:CCT4(gene name)|psi-mi:CCT4(display_short)|uniprotkb:CCTD(gene name synonym)|uniprotkb:SRB(gene name synonym)|uniprotkb:CCT-delta(gene name synonym)|uniprotkb:Stimulator of TAR RNA-binding(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485944|imex:IM-26985-215 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000065717(gene)|ensembl:ENST00000262953(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_001287775.1|refseq:NP_001138233.1|refseq:NP_001138234.1|refseq:NP_003251.2|interpro:IPR019775|interpro:IPR036322|mint:Q04725|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-3769402|reactome:R-HSA-4641265 refseq:NP_006421.2|refseq:NP_001243650.1|dip:DIP-32971N|ensembl:ENSG00000115484(gene)|ensembl:ENST00000394440(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0042470"(melanosome)|go:"GO:0042995"(cell projection)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090666"(scaRNA localization to Cajal body)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012717(T-complex protein 1, delta subunit)|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50991|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-5620922|reactome:R-HSA-6814122|interpro:IPR017998 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QlgGABrHV/Wi5v8Pb3SQAq+1gTU9606 rogid:Erg8Zzajt1WbrByS9LR4NAhZrXM9606 rigid:oAwFfbOzWouvcnQ+jSb8htZDG68 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q04725 uniprotkb:Q99832 intact:EBI-1176061|uniprotkb:Q8WVY0|uniprotkb:Q9Y6S0|ensembl:ENSP00000262953|uniprotkb:B4DE03|uniprotkb:E9PEV7|uniprotkb:F8WCH2 intact:EBI-357046|uniprotkb:B7WNW9|uniprotkb:O14871|uniprotkb:Q6FI26|uniprotkb:A8K7E6|uniprotkb:A8MWI8|uniprotkb:B7Z4T9|uniprotkb:B7Z4Z7|ensembl:ENSP00000258091 psi-mi:tle2_human(display_long)|uniprotkb:Enhancer of split groucho-like protein 2(gene name synonym)|uniprotkb:TLE2(gene name)|psi-mi:TLE2(display_short) psi-mi:tcph_human(display_long)|uniprotkb:CCT7(gene name)|psi-mi:CCT7(display_short)|uniprotkb:CCTH(gene name synonym)|uniprotkb:NIP7-1(gene name synonym)|uniprotkb:CCT-eta(gene name synonym)|uniprotkb:HIV-1 Nef-interacting protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485944|imex:IM-26985-215 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000065717(gene)|ensembl:ENST00000262953(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_001287775.1|refseq:NP_001138233.1|refseq:NP_001138234.1|refseq:NP_003251.2|interpro:IPR019775|interpro:IPR036322|mint:Q04725|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-3769402|reactome:R-HSA-4641265 dip:DIP-51608N|refseq:NP_006420.1|refseq:XP_011530780.1|refseq:XP_011530781.1|refseq:NP_001009570.1|refseq:NP_001159756.1|refseq:NP_001159757.1|ensembl:ENSG00000135624(gene)|ensembl:ENST00000258091(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012720(T-complex protein 1, eta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:Q99832|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|reactome:R-HSA-6814122|reactome:R-HSA-9013418|reactome:R-HSA-9013422 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QlgGABrHV/Wi5v8Pb3SQAq+1gTU9606 rogid:buiW7iGdAbfcld/zMJOrkR2jxRo9606 rigid:oAwFfbOzWouvcnQ+jSb8htZDG68 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q04725 uniprotkb:P50990 intact:EBI-1176061|uniprotkb:Q8WVY0|uniprotkb:Q9Y6S0|ensembl:ENSP00000262953|uniprotkb:B4DE03|uniprotkb:E9PEV7|uniprotkb:F8WCH2 intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788 psi-mi:tle2_human(display_long)|uniprotkb:Enhancer of split groucho-like protein 2(gene name synonym)|uniprotkb:TLE2(gene name)|psi-mi:TLE2(display_short) psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485944|imex:IM-26985-215 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000065717(gene)|ensembl:ENST00000262953(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_001287775.1|refseq:NP_001138233.1|refseq:NP_001138234.1|refseq:NP_003251.2|interpro:IPR019775|interpro:IPR036322|mint:Q04725|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-3769402|reactome:R-HSA-4641265 refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QlgGABrHV/Wi5v8Pb3SQAq+1gTU9606 rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606 rigid:oAwFfbOzWouvcnQ+jSb8htZDG68 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q04725 uniprotkb:Q04724 intact:EBI-1176061|uniprotkb:Q8WVY0|uniprotkb:Q9Y6S0|ensembl:ENSP00000262953|uniprotkb:B4DE03|uniprotkb:E9PEV7|uniprotkb:F8WCH2 intact:EBI-711424|uniprotkb:Q5T3G4|uniprotkb:Q969V9|ensembl:ENSP00000365682|uniprotkb:A8K495 psi-mi:tle2_human(display_long)|uniprotkb:Enhancer of split groucho-like protein 2(gene name synonym)|uniprotkb:TLE2(gene name)|psi-mi:TLE2(display_short) psi-mi:tle1_human(display_long)|uniprotkb:TLE1(gene name)|psi-mi:TLE1(display_short)|uniprotkb:Enhancer of split groucho-like protein 1(gene name synonym)|uniprotkb:"E(Sp1) homolog"(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485944|imex:IM-26985-215 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000065717(gene)|ensembl:ENST00000262953(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_001287775.1|refseq:NP_001138233.1|refseq:NP_001138234.1|refseq:NP_003251.2|interpro:IPR019775|interpro:IPR036322|mint:Q04725|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-3769402|reactome:R-HSA-4641265 mint:Q04724|rcsb pdb:1GXR|rcsb pdb:2CE8|rcsb pdb:2CE9|rcsb pdb:4OM2|rcsb pdb:4OM3|rcsb pdb:5MWJ|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-3769402|reactome:R-HSA-4641265|ensembl:ENSG00000196781(gene)|ensembl:ENST00000376499(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|refseq:NP_005068.2|refseq:NP_001290032.1|refseq:NP_001290033.1|dip:DIP-36665N - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QlgGABrHV/Wi5v8Pb3SQAq+1gTU9606 rogid:mOWun+rOiFbfy4AZ1pQ+K3GRriU9606 rigid:oAwFfbOzWouvcnQ+jSb8htZDG68 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q04725 uniprotkb:Q04727 intact:EBI-1176061|uniprotkb:Q8WVY0|uniprotkb:Q9Y6S0|ensembl:ENSP00000262953|uniprotkb:B4DE03|uniprotkb:E9PEV7|uniprotkb:F8WCH2 intact:EBI-2820683|uniprotkb:Q9NSL3|uniprotkb:Q9ULF9|uniprotkb:Q9BZ07|uniprotkb:Q9BZ09|uniprotkb:Q6PCB3|uniprotkb:Q5T1Y2|uniprotkb:Q9BZ08|uniprotkb:Q3ZCS1|uniprotkb:F8W6T6|ensembl:ENSP00000365735 psi-mi:tle2_human(display_long)|uniprotkb:Enhancer of split groucho-like protein 2(gene name synonym)|uniprotkb:TLE2(gene name)|psi-mi:TLE2(display_short) psi-mi:tle4_human(display_long)|uniprotkb:TLE4(gene name)|psi-mi:TLE4(display_short)|uniprotkb:KIAA1261(gene name synonym)|uniprotkb:GRG4(gene name synonym)|uniprotkb:Grg-4(gene name synonym)|uniprotkb:Groucho-related protein 4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485944|imex:IM-26985-215 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000065717(gene)|ensembl:ENST00000262953(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_001287775.1|refseq:NP_001138233.1|refseq:NP_001138234.1|refseq:NP_003251.2|interpro:IPR019775|interpro:IPR036322|mint:Q04725|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-3769402|reactome:R-HSA-4641265 refseq:NP_001269677.1|refseq:NP_001269682.1|refseq:NP_008936.2|ensembl:ENSG00000106829(gene)|ensembl:ENST00000376552(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|refseq:NP_001269678.1|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|go:"GO:0140297"(DNA-binding transcription factor binding)|mint:Q04727|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-3769402|reactome:R-HSA-4641265 - - comment:"author score: 30" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QlgGABrHV/Wi5v8Pb3SQAq+1gTU9606 rogid:RCmBjb3GTXb9i5NErPsC1UWQuio9606 rigid:oAwFfbOzWouvcnQ+jSb8htZDG68 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q04725 uniprotkb:Q04726 intact:EBI-1176061|uniprotkb:Q8WVY0|uniprotkb:Q9Y6S0|ensembl:ENSP00000262953|uniprotkb:B4DE03|uniprotkb:E9PEV7|uniprotkb:F8WCH2 intact:EBI-1052057|uniprotkb:Q8IVV6|uniprotkb:Q8WVR2|uniprotkb:Q9HCM5|uniprotkb:B4DPT0|uniprotkb:F8W964|uniprotkb:E9PD64|ensembl:ENSP00000452871|uniprotkb:Q6PI57 psi-mi:tle2_human(display_long)|uniprotkb:Enhancer of split groucho-like protein 2(gene name synonym)|uniprotkb:TLE2(gene name)|psi-mi:TLE2(display_short) psi-mi:tle3_human(display_long)|uniprotkb:Enhancer of split groucho-like protein 3(gene name synonym)|uniprotkb:TLE3(gene name)|psi-mi:TLE3(display_short)|uniprotkb:KIAA1547(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485944|imex:IM-26985-215 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000065717(gene)|ensembl:ENST00000262953(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_001287775.1|refseq:NP_001138233.1|refseq:NP_001138234.1|refseq:NP_003251.2|interpro:IPR019775|interpro:IPR036322|mint:Q04725|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-3769402|reactome:R-HSA-4641265 refseq:NP_001098662.1|refseq:NP_005069.2|refseq:NP_065959.1|refseq:NP_001269908.1|refseq:NP_001269909.1|refseq:NP_001269910.1|refseq:NP_001269911.1|ensembl:ENSG00000140332(gene)|ensembl:ENST00000558939(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007165"(signal transduction)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990907"(beta-catenin-TCF complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:Q04726|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-3769402|reactome:R-HSA-4641265|reactome:R-HSA-9018519|dip:DIP-36666N - - comment:"author score: 35" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QlgGABrHV/Wi5v8Pb3SQAq+1gTU9606 rogid:lbsBYgdnyUWioqJ5euhotXA84Xg9606 rigid:oAwFfbOzWouvcnQ+jSb8htZDG68 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q04725 uniprotkb:Q08117 intact:EBI-1176061|uniprotkb:Q8WVY0|uniprotkb:Q9Y6S0|ensembl:ENSP00000262953|uniprotkb:B4DE03|uniprotkb:E9PEV7|uniprotkb:F8WCH2 intact:EBI-717810|uniprotkb:Q12808|uniprotkb:Q96TG9|uniprotkb:Q9UDY9|uniprotkb:B2RBL0|uniprotkb:Q14CJ1|ensembl:ENSP00000317537 psi-mi:tle2_human(display_long)|uniprotkb:Enhancer of split groucho-like protein 2(gene name synonym)|uniprotkb:TLE2(gene name)|psi-mi:TLE2(display_short) psi-mi:tle5_human(display_long)|uniprotkb:TLE5(gene name)|psi-mi:TLE5(display_short)|uniprotkb:AES(gene name synonym)|uniprotkb:Amino-terminal enhancer of split(gene name synonym)|uniprotkb:GRG(gene name synonym)|uniprotkb:GRG5(gene name synonym)|uniprotkb:Gp130-associated protein GAM(gene name synonym)|uniprotkb:Grg-5(gene name synonym)|uniprotkb:Groucho-related protein 5(gene name synonym)|uniprotkb:Protein ESP1(gene name synonym)|uniprotkb:Protein GRG(gene name synonym)|uniprotkb:TLE family member 5, transcriptional modulator(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485944|imex:IM-26985-215 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000065717(gene)|ensembl:ENST00000262953(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016604"(nuclear body)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001680(WD40 repeat)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|interpro:IPR015943(WD40/YVTN repeat-like)|refseq:NP_001287775.1|refseq:NP_001138233.1|refseq:NP_001138234.1|refseq:NP_003251.2|interpro:IPR019775|interpro:IPR036322|mint:Q04725|reactome:R-HSA-201722|reactome:R-HSA-2122947|reactome:R-HSA-3769402|reactome:R-HSA-4641265 refseq:NP_001121.2|refseq:NP_945320.1|refseq:NP_945321.1|ensembl:ENSG00000104964(gene)|ensembl:ENST00000327141(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001501"(skeletal system development)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0007275"(multicellular organism development)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0040008"(regulation of growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:2000210"(positive regulation of anoikis)|interpro:IPR005617(Groucho/TLE, N-terminal Q-rich region)|interpro:IPR009146(Groucho/transducin-like enhancer)|mint:Q08117|reactome:R-HSA-4641265|go:"GO:0032091"(negative regulation of protein binding) - - comment:"author score: 53" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QlgGABrHV/Wi5v8Pb3SQAq+1gTU9606 rogid:eveYX2Rj6Oz431E8nGcTk4bUNt89606 rigid:oAwFfbOzWouvcnQ+jSb8htZDG68 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q12888 uniprotkb:Q8IWS0 intact:EBI-396540|uniprotkb:Q2M1Z7|uniprotkb:Q4LE46|uniprotkb:Q5FWZ3|uniprotkb:Q7Z3U4|ensembl:ENSP00000263801|uniprotkb:F8VY86 intact:EBI-1055194|uniprotkb:Q5JRC8|uniprotkb:Q96JK3|uniprotkb:Q9BRU0|uniprotkb:Q5JRC7|uniprotkb:D3DTG3|uniprotkb:A8K230|uniprotkb:E9PC97|uniprotkb:B4E0G4|ensembl:ENSP00000329097|ensembl:ENSP00000359839 psi-mi:tp53b_human(display_long)|uniprotkb:TP53BP1(gene name)|psi-mi:TP53BP1(display_short) psi-mi:phf6_human(display_long)|uniprotkb:PHD-like zinc finger protein(gene name synonym)|uniprotkb:PHF6(gene name)|psi-mi:PHF6(display_short)|uniprotkb:KIAA1823(gene name synonym)|uniprotkb:CENP-31(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486067|imex:IM-26985-449 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001135451.1|refseq:NP_001135452.1|refseq:NP_005648.1|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0042393"(histone binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061649"(ubiquitin modification-dependent histone binding)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:1990391"(DNA repair complex)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|interpro:IPR001357(BRCT)|interpro:IPR002999(Tudor)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR015125(Tumour suppressor p53-binding protein-1 Tudor)|interpro:IPR036420|mint:Q12888|reactome:R-HSA-5693607|reactome:R-HSA-69473|rcsb pdb:1GZH|rcsb pdb:1KZY|rcsb pdb:1XNI|rcsb pdb:2G3R|rcsb pdb:2IG0|rcsb pdb:2LVM|rcsb pdb:2MWO|rcsb pdb:2MWP|rcsb pdb:3LGF|rcsb pdb:3LGL|rcsb pdb:3LH0|rcsb pdb:4CRI|rcsb pdb:4RG2|rcsb pdb:4X34|rcsb pdb:5ECG|rcsb pdb:5J26|rcsb pdb:5KGF|rcsb pdb:5Z78|rcsb pdb:5ZCJ|rcsb pdb:6CO1|rcsb pdb:6CO2|rcsb pdb:6IU7|rcsb pdb:6IUA|rcsb pdb:6MXX|rcsb pdb:6MXY|rcsb pdb:6MXZ|rcsb pdb:6MY0|rcsb pdb:6RML|rcsb pdb:6RMM|rcsb pdb:6UPT|rcsb pdb:6VA5|rcsb pdb:6VIP|rcsb pdb:7LIN|rcsb pdb:7LIO|reactome:R-HSA-3232118|reactome:R-HSA-5693565|reactome:R-HSA-5693571|ensembl:ENSG00000067369(gene)|ensembl:ENST00000263801(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000776"(kinetochore)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0002039"(p53 binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042162"(telomeric DNA binding)|dip:DIP-5978N refseq:NP_001015877.1|refseq:NP_115711.2|refseq:NP_115834.1|ensembl:ENSG00000156531(gene)|ensembl:ENST00000332070(transcript)|ensembl:ENST00000370803(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000776"(kinetochore)|go:"GO:0001835"(blastocyst hatching)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0015631"(tubulin binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0042393"(histone binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0097110"(scaffold protein binding)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR034732|mint:Q8IWS0|rcsb pdb:4NN2|rcsb pdb:4R7A|go:"GO:0005730"(nucleolus) - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRksPL7aJniN+0thiLfIdeythoU9606 rogid:ZHj/64dPBMmA7GOgpdtHLxeNOu49606 rigid:8y+U2NE6AQRbEBaf7V8QsUjTFuo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q12888 uniprotkb:P30533 intact:EBI-396540|uniprotkb:Q2M1Z7|uniprotkb:Q4LE46|uniprotkb:Q5FWZ3|uniprotkb:Q7Z3U4|ensembl:ENSP00000263801|uniprotkb:F8VY86 intact:EBI-715927|uniprotkb:Q2M310|uniprotkb:Q53HQ3|uniprotkb:Q53HS6|uniprotkb:D3DVR9|ensembl:ENSP00000497444 psi-mi:tp53b_human(display_long)|uniprotkb:TP53BP1(gene name)|psi-mi:TP53BP1(display_short) psi-mi:amrp_human(display_long)|uniprotkb:Low density lipoprotein receptor-related protein-associated protein 1(gene name synonym)|uniprotkb:LRPAP1(gene name)|psi-mi:LRPAP1(display_short)|uniprotkb:A2MRAP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486067|imex:IM-26985-449 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001135451.1|refseq:NP_001135452.1|refseq:NP_005648.1|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0042393"(histone binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061649"(ubiquitin modification-dependent histone binding)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:1990391"(DNA repair complex)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|interpro:IPR001357(BRCT)|interpro:IPR002999(Tudor)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR015125(Tumour suppressor p53-binding protein-1 Tudor)|interpro:IPR036420|mint:Q12888|reactome:R-HSA-5693607|reactome:R-HSA-69473|rcsb pdb:1GZH|rcsb pdb:1KZY|rcsb pdb:1XNI|rcsb pdb:2G3R|rcsb pdb:2IG0|rcsb pdb:2LVM|rcsb pdb:2MWO|rcsb pdb:2MWP|rcsb pdb:3LGF|rcsb pdb:3LGL|rcsb pdb:3LH0|rcsb pdb:4CRI|rcsb pdb:4RG2|rcsb pdb:4X34|rcsb pdb:5ECG|rcsb pdb:5J26|rcsb pdb:5KGF|rcsb pdb:5Z78|rcsb pdb:5ZCJ|rcsb pdb:6CO1|rcsb pdb:6CO2|rcsb pdb:6IU7|rcsb pdb:6IUA|rcsb pdb:6MXX|rcsb pdb:6MXY|rcsb pdb:6MXZ|rcsb pdb:6MY0|rcsb pdb:6RML|rcsb pdb:6RMM|rcsb pdb:6UPT|rcsb pdb:6VA5|rcsb pdb:6VIP|rcsb pdb:7LIN|rcsb pdb:7LIO|reactome:R-HSA-3232118|reactome:R-HSA-5693565|reactome:R-HSA-5693571|ensembl:ENSG00000067369(gene)|ensembl:ENST00000263801(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000776"(kinetochore)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0002039"(p53 binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042162"(telomeric DNA binding)|dip:DIP-5978N refseq:NP_002328.1|ensembl:ENSG00000163956(gene)|ensembl:ENST00000650182(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0008201"(heparin binding)|go:"GO:0009986"(cell surface)|go:"GO:0010916"(negative regulation of very-low-density lipoprotein particle clearance)|go:"GO:0012505"(endomembrane system)|go:"GO:0031904"(endosome lumen)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0035473"(lipase binding)|go:"GO:0048018"(receptor ligand activity)|go:"GO:0048019"(receptor antagonist activity)|go:"GO:0048237"(rough endoplasmic reticulum lumen)|go:"GO:0048259"(regulation of receptor-mediated endocytosis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070326"(very-low-density lipoprotein particle receptor binding)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1900116"(extracellular negative regulation of signal transduction)|go:"GO:1900222"(negative regulation of amyloid-beta clearance)|go:"GO:1900223"(positive regulation of amyloid-beta clearance)|interpro:IPR009066(Alpha-2-macroglobulin receptor-associated protein, domain 1)|interpro:IPR010483(Alpha-2-macroglobulin RAP, C-terminal)|interpro:IPR036744|interpro:IPR037999|interpro:IPR038001|interpro:IPR038003|mint:P30533|rcsb pdb:1LRE|rcsb pdb:1NRE|rcsb pdb:1OP1|rcsb pdb:1OV2|rcsb pdb:2FCW|rcsb pdb:2FTU|rcsb pdb:2FYL|rcsb pdb:2P01|rcsb pdb:2P03|dip:DIP-39355N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRksPL7aJniN+0thiLfIdeythoU9606 rogid:TIbL+P1GW4op4Qawa4lpg8iXUaQ9606 rigid:8y+U2NE6AQRbEBaf7V8QsUjTFuo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q12888 uniprotkb:Q96EY4 intact:EBI-396540|uniprotkb:Q2M1Z7|uniprotkb:Q4LE46|uniprotkb:Q5FWZ3|uniprotkb:Q7Z3U4|ensembl:ENSP00000263801|uniprotkb:F8VY86 intact:EBI-1045338|uniprotkb:Q0P6E4|uniprotkb:Q0P6J1|uniprotkb:Q9NUR7|ensembl:ENSP00000351380 psi-mi:tp53b_human(display_long)|uniprotkb:TP53BP1(gene name)|psi-mi:TP53BP1(display_short) psi-mi:tma16_human(display_long)|uniprotkb:TMA16(gene name)|psi-mi:TMA16(display_short)|uniprotkb:C4orf43(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486067|imex:IM-26985-449 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001135451.1|refseq:NP_001135452.1|refseq:NP_005648.1|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0042393"(histone binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061649"(ubiquitin modification-dependent histone binding)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:1990391"(DNA repair complex)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|interpro:IPR001357(BRCT)|interpro:IPR002999(Tudor)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR015125(Tumour suppressor p53-binding protein-1 Tudor)|interpro:IPR036420|mint:Q12888|reactome:R-HSA-5693607|reactome:R-HSA-69473|rcsb pdb:1GZH|rcsb pdb:1KZY|rcsb pdb:1XNI|rcsb pdb:2G3R|rcsb pdb:2IG0|rcsb pdb:2LVM|rcsb pdb:2MWO|rcsb pdb:2MWP|rcsb pdb:3LGF|rcsb pdb:3LGL|rcsb pdb:3LH0|rcsb pdb:4CRI|rcsb pdb:4RG2|rcsb pdb:4X34|rcsb pdb:5ECG|rcsb pdb:5J26|rcsb pdb:5KGF|rcsb pdb:5Z78|rcsb pdb:5ZCJ|rcsb pdb:6CO1|rcsb pdb:6CO2|rcsb pdb:6IU7|rcsb pdb:6IUA|rcsb pdb:6MXX|rcsb pdb:6MXY|rcsb pdb:6MXZ|rcsb pdb:6MY0|rcsb pdb:6RML|rcsb pdb:6RMM|rcsb pdb:6UPT|rcsb pdb:6VA5|rcsb pdb:6VIP|rcsb pdb:7LIN|rcsb pdb:7LIO|reactome:R-HSA-3232118|reactome:R-HSA-5693565|reactome:R-HSA-5693571|ensembl:ENSG00000067369(gene)|ensembl:ENST00000263801(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000776"(kinetochore)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0002039"(p53 binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042162"(telomeric DNA binding)|dip:DIP-5978N refseq:NP_060822.2|ensembl:ENSG00000198498(gene)|ensembl:ENST00000358572(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|interpro:IPR021346|interpro:IPR038356|mint:Q96EY4|rcsb pdb:6LSS|rcsb pdb:6LU8 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRksPL7aJniN+0thiLfIdeythoU9606 rogid:SpEUtN6fodLyKZOgY6Y7AXfVBRY9606 rigid:8y+U2NE6AQRbEBaf7V8QsUjTFuo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q12888 uniprotkb:P22531 intact:EBI-396540|uniprotkb:Q2M1Z7|uniprotkb:Q4LE46|uniprotkb:Q5FWZ3|uniprotkb:Q7Z3U4|ensembl:ENSP00000263801|uniprotkb:F8VY86 intact:EBI-2556846|uniprotkb:Q5T9T4|uniprotkb:Q96RM2|ensembl:ENSP00000357739|ensembl:ENSP00000357740 psi-mi:tp53b_human(display_long)|uniprotkb:TP53BP1(gene name)|psi-mi:TP53BP1(display_short) psi-mi:spr2e_human(display_long)|uniprotkb:Small proline-rich protein II(gene name synonym)|uniprotkb:SPRR2E(gene name)|psi-mi:SPRR2E(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486067|imex:IM-26985-449 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001135451.1|refseq:NP_001135452.1|refseq:NP_005648.1|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0042393"(histone binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061649"(ubiquitin modification-dependent histone binding)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:1990391"(DNA repair complex)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|interpro:IPR001357(BRCT)|interpro:IPR002999(Tudor)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR015125(Tumour suppressor p53-binding protein-1 Tudor)|interpro:IPR036420|mint:Q12888|reactome:R-HSA-5693607|reactome:R-HSA-69473|rcsb pdb:1GZH|rcsb pdb:1KZY|rcsb pdb:1XNI|rcsb pdb:2G3R|rcsb pdb:2IG0|rcsb pdb:2LVM|rcsb pdb:2MWO|rcsb pdb:2MWP|rcsb pdb:3LGF|rcsb pdb:3LGL|rcsb pdb:3LH0|rcsb pdb:4CRI|rcsb pdb:4RG2|rcsb pdb:4X34|rcsb pdb:5ECG|rcsb pdb:5J26|rcsb pdb:5KGF|rcsb pdb:5Z78|rcsb pdb:5ZCJ|rcsb pdb:6CO1|rcsb pdb:6CO2|rcsb pdb:6IU7|rcsb pdb:6IUA|rcsb pdb:6MXX|rcsb pdb:6MXY|rcsb pdb:6MXZ|rcsb pdb:6MY0|rcsb pdb:6RML|rcsb pdb:6RMM|rcsb pdb:6UPT|rcsb pdb:6VA5|rcsb pdb:6VIP|rcsb pdb:7LIN|rcsb pdb:7LIO|reactome:R-HSA-3232118|reactome:R-HSA-5693565|reactome:R-HSA-5693571|ensembl:ENSG00000067369(gene)|ensembl:ENST00000263801(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000776"(kinetochore)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0002039"(p53 binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042162"(telomeric DNA binding)|dip:DIP-5978N refseq:NP_001019380.2|ensembl:ENSG00000203785(gene)|ensembl:ENST00000368750(transcript)|ensembl:ENST00000368751(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030280"(structural constituent of skin epidermis)|go:"GO:0031424"(keratinization)|interpro:IPR029142|mint:P22531|reactome:R-HSA-6809371 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRksPL7aJniN+0thiLfIdeythoU9606 rogid:Pwemojva9RHkLb7mVmctpxenpf49606 rigid:8y+U2NE6AQRbEBaf7V8QsUjTFuo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q12888 uniprotkb:O14874 intact:EBI-396540|uniprotkb:Q2M1Z7|uniprotkb:Q4LE46|uniprotkb:Q5FWZ3|uniprotkb:Q7Z3U4|ensembl:ENSP00000263801|uniprotkb:F8VY86 intact:EBI-1046765|uniprotkb:Q96IN5|uniprotkb:Q6FGL4|intact:EBI-1210327|uniprotkb:A8MY43|uniprotkb:Q96G95|ensembl:ENSP00000219794|ensembl:ENSP00000378405 psi-mi:tp53b_human(display_long)|uniprotkb:TP53BP1(gene name)|psi-mi:TP53BP1(display_short) psi-mi:bckd_human(display_long)|uniprotkb:Branched-chain alpha-ketoacid dehydrogenase kinase(gene name synonym)|uniprotkb:BCKDK(gene name)|psi-mi:BCKDK(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486067|imex:IM-26985-449 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001135451.1|refseq:NP_001135452.1|refseq:NP_005648.1|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0042393"(histone binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061649"(ubiquitin modification-dependent histone binding)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:1990391"(DNA repair complex)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|interpro:IPR001357(BRCT)|interpro:IPR002999(Tudor)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR015125(Tumour suppressor p53-binding protein-1 Tudor)|interpro:IPR036420|mint:Q12888|reactome:R-HSA-5693607|reactome:R-HSA-69473|rcsb pdb:1GZH|rcsb pdb:1KZY|rcsb pdb:1XNI|rcsb pdb:2G3R|rcsb pdb:2IG0|rcsb pdb:2LVM|rcsb pdb:2MWO|rcsb pdb:2MWP|rcsb pdb:3LGF|rcsb pdb:3LGL|rcsb pdb:3LH0|rcsb pdb:4CRI|rcsb pdb:4RG2|rcsb pdb:4X34|rcsb pdb:5ECG|rcsb pdb:5J26|rcsb pdb:5KGF|rcsb pdb:5Z78|rcsb pdb:5ZCJ|rcsb pdb:6CO1|rcsb pdb:6CO2|rcsb pdb:6IU7|rcsb pdb:6IUA|rcsb pdb:6MXX|rcsb pdb:6MXY|rcsb pdb:6MXZ|rcsb pdb:6MY0|rcsb pdb:6RML|rcsb pdb:6RMM|rcsb pdb:6UPT|rcsb pdb:6VA5|rcsb pdb:6VIP|rcsb pdb:7LIN|rcsb pdb:7LIO|reactome:R-HSA-3232118|reactome:R-HSA-5693565|reactome:R-HSA-5693571|ensembl:ENSG00000067369(gene)|ensembl:ENST00000263801(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000776"(kinetochore)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0002039"(p53 binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042162"(telomeric DNA binding)|dip:DIP-5978N refseq:NP_005872.2|go:"GO:0005947"(mitochondrial alpha-ketoglutarate dehydrogenase complex)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006550"(isoleucine catabolic process)|go:"GO:0006552"(leucine catabolic process)|go:"GO:0006574"(valine catabolic process)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009063"(cellular amino acid catabolic process)|go:"GO:0009083"(branched-chain amino acid catabolic process)|go:"GO:0010906"(regulation of glucose metabolic process)|go:"GO:0016301"(kinase activity)|go:"GO:0016310"(phosphorylation)|go:"GO:0045763"(negative regulation of cellular amino acid metabolic process)|go:"GO:0047323"("[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity")|interpro:IPR003594(ATP-binding region, ATPase-like)|refseq:NP_001116429.1|refseq:NP_001258855.1|interpro:IPR004358(Signal transduction histidine kinase-related protein, C-terminal)|interpro:IPR005467(Signal transduction histidine kinase, core)|interpro:IPR018955|go:"GO:0005759"(mitochondrial matrix)|interpro:IPR036784|interpro:IPR036890|interpro:IPR039028|mint:O14874|reactome:R-HSA-70895|ensembl:ENSG00000103507(gene)|ensembl:ENST00000219794(transcript)|ensembl:ENST00000394951(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004740"("pyruvate dehydrogenase (acetyl-transferring) kinase activity")|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion) - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRksPL7aJniN+0thiLfIdeythoU9606 rogid:0hiSb7/qtSPoHt/cmLnUo7Gq6OI9606 rigid:8y+U2NE6AQRbEBaf7V8QsUjTFuo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q12888 uniprotkb:Q9UBP6 intact:EBI-396540|uniprotkb:Q2M1Z7|uniprotkb:Q4LE46|uniprotkb:Q5FWZ3|uniprotkb:Q7Z3U4|ensembl:ENSP00000263801|uniprotkb:F8VY86 intact:EBI-750415|uniprotkb:Q14105|uniprotkb:B2RBX1|uniprotkb:H7BXF2|uniprotkb:Q53FS9|ensembl:ENSP00000314441 psi-mi:tp53b_human(display_long)|uniprotkb:TP53BP1(gene name)|psi-mi:TP53BP1(display_short) psi-mi:trmb_human(display_long)|uniprotkb:"tRNA(m7G46)-methyltransferase"(gene name synonym)|uniprotkb:Methyltransferase-like protein 1(gene name synonym)|uniprotkb:"tRNA (guanine(46)-N(7))-methyltransferase"(gene name synonym)|uniprotkb:METTL1(gene name)|psi-mi:METTL1(display_short)|uniprotkb:C12orf1(gene name synonym)|uniprotkb:"mRNA (guanine-N(7)-)-methyltransferase"(gene name synonym)|uniprotkb:"miRNA (guanine-N(7)-)-methyltransferase"(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486067|imex:IM-26985-449 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001135451.1|refseq:NP_001135452.1|refseq:NP_005648.1|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0042393"(histone binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061649"(ubiquitin modification-dependent histone binding)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:1990391"(DNA repair complex)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|interpro:IPR001357(BRCT)|interpro:IPR002999(Tudor)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR015125(Tumour suppressor p53-binding protein-1 Tudor)|interpro:IPR036420|mint:Q12888|reactome:R-HSA-5693607|reactome:R-HSA-69473|rcsb pdb:1GZH|rcsb pdb:1KZY|rcsb pdb:1XNI|rcsb pdb:2G3R|rcsb pdb:2IG0|rcsb pdb:2LVM|rcsb pdb:2MWO|rcsb pdb:2MWP|rcsb pdb:3LGF|rcsb pdb:3LGL|rcsb pdb:3LH0|rcsb pdb:4CRI|rcsb pdb:4RG2|rcsb pdb:4X34|rcsb pdb:5ECG|rcsb pdb:5J26|rcsb pdb:5KGF|rcsb pdb:5Z78|rcsb pdb:5ZCJ|rcsb pdb:6CO1|rcsb pdb:6CO2|rcsb pdb:6IU7|rcsb pdb:6IUA|rcsb pdb:6MXX|rcsb pdb:6MXY|rcsb pdb:6MXZ|rcsb pdb:6MY0|rcsb pdb:6RML|rcsb pdb:6RMM|rcsb pdb:6UPT|rcsb pdb:6VA5|rcsb pdb:6VIP|rcsb pdb:7LIN|rcsb pdb:7LIO|reactome:R-HSA-3232118|reactome:R-HSA-5693565|reactome:R-HSA-5693571|ensembl:ENSG00000067369(gene)|ensembl:ENST00000263801(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000776"(kinetochore)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0002039"(p53 binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042162"(telomeric DNA binding)|dip:DIP-5978N refseq:NP_005362.3|refseq:NP_075422.3|dip:DIP-61920N|ensembl:ENSG00000037897(gene)|ensembl:ENST00000324871(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006400"(tRNA modification)|go:"GO:0008176"("tRNA (guanine-N7-)-methyltransferase activity")|go:"GO:0030488"(tRNA methylation)|go:"GO:0036265"("RNA (guanine-N7)-methylation")|go:"GO:0043527"(tRNA methyltransferase complex)|interpro:IPR003358(Putative methyltransferase)|interpro:IPR025763|interpro:IPR029063|mint:Q9UBP6|rcsb pdb:3CKK|rcsb pdb:7OGJ|reactome:R-HSA-6782315 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRksPL7aJniN+0thiLfIdeythoU9606 rogid:3Nq+5mb2iCLNZP+Y0LSsiIzVUlY9606 rigid:8y+U2NE6AQRbEBaf7V8QsUjTFuo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q12888 uniprotkb:P48426 intact:EBI-396540|uniprotkb:Q2M1Z7|uniprotkb:Q4LE46|uniprotkb:Q5FWZ3|uniprotkb:Q7Z3U4|ensembl:ENSP00000263801|uniprotkb:F8VY86 intact:EBI-3924422|uniprotkb:Q5VUX3|uniprotkb:D3DRV1|uniprotkb:B0YJ66|uniprotkb:P53807|ensembl:ENSP00000365757|uniprotkb:B4DGX2 psi-mi:tp53b_human(display_long)|uniprotkb:TP53BP1(gene name)|psi-mi:TP53BP1(display_short) psi-mi:pi42a_human(display_long)|uniprotkb:PIP4K2A(gene name)|psi-mi:PIP4K2A(display_short)|uniprotkb:PIP5K2(gene name synonym)|uniprotkb:PIP5K2A(gene name synonym)|uniprotkb:Diphosphoinositide kinase 2-alpha(gene name synonym)|uniprotkb:PIP5KIII(gene name synonym)|uniprotkb:"PtdIns(4)P-5-kinase B isoform"(gene name synonym)|uniprotkb:"PtdIns(4)P-5-kinase C isoform"(gene name synonym)|uniprotkb:"PtdIns(5)P-4-kinase isoform 2-alpha"(gene name synonym)|uniprotkb:1-phosphatidylinositol 5-phosphate 4-kinase 2-alpha(gene name synonym)|uniprotkb:Phosphatidylinositol 5-phosphate 4-kinase type II alpha(gene name synonym)|uniprotkb:PI5P4KA(gene name synonym)|uniprotkb:Phosphatidylinositol 5-Phosphate 4-Kinase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486067|imex:IM-26985-449 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001135451.1|refseq:NP_001135452.1|refseq:NP_005648.1|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0042393"(histone binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061649"(ubiquitin modification-dependent histone binding)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:1990391"(DNA repair complex)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|interpro:IPR001357(BRCT)|interpro:IPR002999(Tudor)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR015125(Tumour suppressor p53-binding protein-1 Tudor)|interpro:IPR036420|mint:Q12888|reactome:R-HSA-5693607|reactome:R-HSA-69473|rcsb pdb:1GZH|rcsb pdb:1KZY|rcsb pdb:1XNI|rcsb pdb:2G3R|rcsb pdb:2IG0|rcsb pdb:2LVM|rcsb pdb:2MWO|rcsb pdb:2MWP|rcsb pdb:3LGF|rcsb pdb:3LGL|rcsb pdb:3LH0|rcsb pdb:4CRI|rcsb pdb:4RG2|rcsb pdb:4X34|rcsb pdb:5ECG|rcsb pdb:5J26|rcsb pdb:5KGF|rcsb pdb:5Z78|rcsb pdb:5ZCJ|rcsb pdb:6CO1|rcsb pdb:6CO2|rcsb pdb:6IU7|rcsb pdb:6IUA|rcsb pdb:6MXX|rcsb pdb:6MXY|rcsb pdb:6MXZ|rcsb pdb:6MY0|rcsb pdb:6RML|rcsb pdb:6RMM|rcsb pdb:6UPT|rcsb pdb:6VA5|rcsb pdb:6VIP|rcsb pdb:7LIN|rcsb pdb:7LIO|reactome:R-HSA-3232118|reactome:R-HSA-5693565|reactome:R-HSA-5693571|ensembl:ENSG00000067369(gene)|ensembl:ENST00000263801(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000776"(kinetochore)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0002039"(p53 binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042162"(telomeric DNA binding)|dip:DIP-5978N refseq:NP_005019.2|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016308"(1-phosphatidylinositol-4-phosphate 5-kinase activity)|go:"GO:0016309"(1-phosphatidylinositol-5-phosphate 4-kinase activity)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0061909"(autophagosome-lysosome fusion)|go:"GO:0090119"(vesicle-mediated cholesterol transport)|go:"GO:0090217"(negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity)|ensembl:ENST00000376573(transcript)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR002498(Phosphatidylinositol-4-phosphate 5-kinase, core)|interpro:IPR023610|interpro:IPR027484|mint:P48426|rcsb pdb:2YBX|rcsb pdb:6OSP|rcsb pdb:6UX9|rcsb pdb:6YM3|rcsb pdb:6YM4|rcsb pdb:6YM5|rcsb pdb:7N6Z|rcsb pdb:7N7J|rcsb pdb:7N7K|rcsb pdb:7N7L|rcsb pdb:7N7M|rcsb pdb:7N7N|rcsb pdb:7N7O|reactome:R-HSA-1660499|reactome:R-HSA-6811555|reactome:R-HSA-6811558|reactome:R-HSA-8847453|go:"GO:1902635"(1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process)|ensembl:ENSG00000150867(gene)|refseq:NP_001316991.1|refseq:XP_016871819.1|refseq:XP_016871820.1 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRksPL7aJniN+0thiLfIdeythoU9606 rogid:Fmsp/H2ucCjs7wyiCgEqe9Y5UT49606 rigid:8y+U2NE6AQRbEBaf7V8QsUjTFuo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q12888 uniprotkb:P49674 intact:EBI-396540|uniprotkb:Q2M1Z7|uniprotkb:Q4LE46|uniprotkb:Q5FWZ3|uniprotkb:Q7Z3U4|ensembl:ENSP00000263801|uniprotkb:F8VY86 intact:EBI-749343|ensembl:ENSP00000352929|ensembl:ENSP00000380044|ensembl:ENSP00000384074 psi-mi:tp53b_human(display_long)|uniprotkb:TP53BP1(gene name)|psi-mi:TP53BP1(display_short) psi-mi:kc1e_human(display_long)|uniprotkb:CSNK1E(gene name)|psi-mi:CSNK1E(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486067|imex:IM-26985-449 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001135451.1|refseq:NP_001135452.1|refseq:NP_005648.1|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0042393"(histone binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061649"(ubiquitin modification-dependent histone binding)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:1990391"(DNA repair complex)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|interpro:IPR001357(BRCT)|interpro:IPR002999(Tudor)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR015125(Tumour suppressor p53-binding protein-1 Tudor)|interpro:IPR036420|mint:Q12888|reactome:R-HSA-5693607|reactome:R-HSA-69473|rcsb pdb:1GZH|rcsb pdb:1KZY|rcsb pdb:1XNI|rcsb pdb:2G3R|rcsb pdb:2IG0|rcsb pdb:2LVM|rcsb pdb:2MWO|rcsb pdb:2MWP|rcsb pdb:3LGF|rcsb pdb:3LGL|rcsb pdb:3LH0|rcsb pdb:4CRI|rcsb pdb:4RG2|rcsb pdb:4X34|rcsb pdb:5ECG|rcsb pdb:5J26|rcsb pdb:5KGF|rcsb pdb:5Z78|rcsb pdb:5ZCJ|rcsb pdb:6CO1|rcsb pdb:6CO2|rcsb pdb:6IU7|rcsb pdb:6IUA|rcsb pdb:6MXX|rcsb pdb:6MXY|rcsb pdb:6MXZ|rcsb pdb:6MY0|rcsb pdb:6RML|rcsb pdb:6RMM|rcsb pdb:6UPT|rcsb pdb:6VA5|rcsb pdb:6VIP|rcsb pdb:7LIN|rcsb pdb:7LIO|reactome:R-HSA-3232118|reactome:R-HSA-5693565|reactome:R-HSA-5693571|ensembl:ENSG00000067369(gene)|ensembl:ENST00000263801(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000776"(kinetochore)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0002039"(p53 binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042162"(telomeric DNA binding)|dip:DIP-5978N refseq:NP_001885.1|refseq:NP_689407.1|refseq:NP_001276841.1|dip:DIP-38050N|ensembl:ENSG00000213923(gene)|ensembl:ENST00000359867(transcript)|ensembl:ENST00000396832(transcript)|ensembl:ENST00000403904(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903827"|go:"GO:0005829"(cytosol)|go:"GO:1905426"(positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation)|go:"GO:2000052"(positive regulation of non-canonical Wnt signaling pathway)|interpro:IPR000719(Protein kinase, core)|reactome:R-HSA-400253|interpro:IPR008271(Serine/threonine protein kinase, active site)|reactome:R-HSA-5620912|reactome:R-HSA-6791226|reactome:R-HSA-8854518|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:P49674|rcsb pdb:4HNI|rcsb pdb:4HOK|reactome:R-HSA-201688|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRksPL7aJniN+0thiLfIdeythoU9606 rogid:evdzz03ba4MFWavN9xRae/Wxwio9606 rigid:8y+U2NE6AQRbEBaf7V8QsUjTFuo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q12888 uniprotkb:P63220 intact:EBI-396540|uniprotkb:Q2M1Z7|uniprotkb:Q4LE46|uniprotkb:Q5FWZ3|uniprotkb:Q7Z3U4|ensembl:ENSP00000263801|uniprotkb:F8VY86 intact:EBI-714051|uniprotkb:P35265|ensembl:ENSP00000345957 psi-mi:tp53b_human(display_long)|uniprotkb:TP53BP1(gene name)|psi-mi:TP53BP1(display_short) psi-mi:rs21_human(display_long)|uniprotkb:RPS21(gene name)|psi-mi:RPS21(display_short)|uniprotkb:Small ribosomal subunit protein eS21(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486067|imex:IM-26985-449 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001135451.1|refseq:NP_001135452.1|refseq:NP_005648.1|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0042393"(histone binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061649"(ubiquitin modification-dependent histone binding)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:1990391"(DNA repair complex)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|interpro:IPR001357(BRCT)|interpro:IPR002999(Tudor)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR015125(Tumour suppressor p53-binding protein-1 Tudor)|interpro:IPR036420|mint:Q12888|reactome:R-HSA-5693607|reactome:R-HSA-69473|rcsb pdb:1GZH|rcsb pdb:1KZY|rcsb pdb:1XNI|rcsb pdb:2G3R|rcsb pdb:2IG0|rcsb pdb:2LVM|rcsb pdb:2MWO|rcsb pdb:2MWP|rcsb pdb:3LGF|rcsb pdb:3LGL|rcsb pdb:3LH0|rcsb pdb:4CRI|rcsb pdb:4RG2|rcsb pdb:4X34|rcsb pdb:5ECG|rcsb pdb:5J26|rcsb pdb:5KGF|rcsb pdb:5Z78|rcsb pdb:5ZCJ|rcsb pdb:6CO1|rcsb pdb:6CO2|rcsb pdb:6IU7|rcsb pdb:6IUA|rcsb pdb:6MXX|rcsb pdb:6MXY|rcsb pdb:6MXZ|rcsb pdb:6MY0|rcsb pdb:6RML|rcsb pdb:6RMM|rcsb pdb:6UPT|rcsb pdb:6VA5|rcsb pdb:6VIP|rcsb pdb:7LIN|rcsb pdb:7LIO|reactome:R-HSA-3232118|reactome:R-HSA-5693565|reactome:R-HSA-5693571|ensembl:ENSG00000067369(gene)|ensembl:ENST00000263801(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000776"(kinetochore)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0002039"(p53 binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042162"(telomeric DNA binding)|dip:DIP-5978N ensembl:ENSG00000171858(gene)|ensembl:ENST00000343986(transcript)|go:"GO:0000447"("endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000461"("endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|refseq:NP_001015.1|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:0047485"(protein N-terminus binding)|interpro:IPR001931(Ribosomal protein S21e)|interpro:IPR018279|interpro:IPR038579|mint:P63220|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6ZMO|rcsb pdb:6G5H|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6G5I|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-156902|rcsb pdb:7K5I|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRksPL7aJniN+0thiLfIdeythoU9606 rogid:3gi91+fAL7ogzcoJlVEaN4D+87A9606 rigid:8y+U2NE6AQRbEBaf7V8QsUjTFuo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q12888 uniprotkb:O94813 intact:EBI-396540|uniprotkb:Q2M1Z7|uniprotkb:Q4LE46|uniprotkb:Q5FWZ3|uniprotkb:Q7Z3U4|ensembl:ENSP00000263801|uniprotkb:F8VY86 intact:EBI-1236865|uniprotkb:O95710|uniprotkb:Q17RU3|uniprotkb:Q9Y5Q7|uniprotkb:B7ZLR5|uniprotkb:A0A0A6YYB8|ensembl:ENSP00000422591 psi-mi:tp53b_human(display_long)|uniprotkb:TP53BP1(gene name)|psi-mi:TP53BP1(display_short) psi-mi:slit2_human(display_long)|uniprotkb:SLIT2(gene name)|psi-mi:SLIT2(display_short)|uniprotkb:SLIL3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486067|imex:IM-26985-449 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001135451.1|refseq:NP_001135452.1|refseq:NP_005648.1|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0042393"(histone binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0061649"(ubiquitin modification-dependent histone binding)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:1990391"(DNA repair complex)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|interpro:IPR001357(BRCT)|interpro:IPR002999(Tudor)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR015125(Tumour suppressor p53-binding protein-1 Tudor)|interpro:IPR036420|mint:Q12888|reactome:R-HSA-5693607|reactome:R-HSA-69473|rcsb pdb:1GZH|rcsb pdb:1KZY|rcsb pdb:1XNI|rcsb pdb:2G3R|rcsb pdb:2IG0|rcsb pdb:2LVM|rcsb pdb:2MWO|rcsb pdb:2MWP|rcsb pdb:3LGF|rcsb pdb:3LGL|rcsb pdb:3LH0|rcsb pdb:4CRI|rcsb pdb:4RG2|rcsb pdb:4X34|rcsb pdb:5ECG|rcsb pdb:5J26|rcsb pdb:5KGF|rcsb pdb:5Z78|rcsb pdb:5ZCJ|rcsb pdb:6CO1|rcsb pdb:6CO2|rcsb pdb:6IU7|rcsb pdb:6IUA|rcsb pdb:6MXX|rcsb pdb:6MXY|rcsb pdb:6MXZ|rcsb pdb:6MY0|rcsb pdb:6RML|rcsb pdb:6RMM|rcsb pdb:6UPT|rcsb pdb:6VA5|rcsb pdb:6VIP|rcsb pdb:7LIN|rcsb pdb:7LIO|reactome:R-HSA-3232118|reactome:R-HSA-5693565|reactome:R-HSA-5693571|ensembl:ENSG00000067369(gene)|ensembl:ENST00000263801(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000776"(kinetochore)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0002039"(p53 binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016604"(nuclear body)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042162"(telomeric DNA binding)|dip:DIP-5978N refseq:NP_001276064.1|refseq:NP_001276065.1|refseq:NP_004778.1|dip:DIP-38198N|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0035385"(Roundabout signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007411"(axon guidance)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008201"(heparin binding)|go:"GO:0009986"(cell surface)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0014912"(negative regulation of smooth muscle cell migration)|go:"GO:0016020"(membrane)|go:"GO:0021836"(chemorepulsion involved in postnatal olfactory bulb interneuron migration)|go:"GO:0021972"(corticospinal neuron axon guidance through spinal cord)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0032870"(cellular response to hormone stimulus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043237"(laminin-1 binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0048495"(Roundabout binding)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0048846"(axon extension involved in axon guidance)|go:"GO:0050772"(positive regulation of axonogenesis)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0050929"(induction of negative chemotaxis)|go:"GO:0051058"(negative regulation of small GTPase mediated signal transduction)|go:"GO:0051414"(response to cortisol)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0061364"(apoptotic process involved in luteolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070100"(negative regulation of chemokine-mediated signaling pathway)|go:"GO:0071504"(cellular response to heparin)|go:"GO:0071672"(negative regulation of smooth muscle cell chemotaxis)|go:"GO:0071676"(negative regulation of mononuclear cell migration)|go:"GO:0090024"(negative regulation of neutrophil chemotaxis)|go:"GO:0090027"(negative regulation of monocyte chemotaxis)|go:"GO:0090260"(negative regulation of retinal ganglion cell axon guidance)|go:"GO:0090288"(negative regulation of cellular response to growth factor stimulus)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001791(Laminin G)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003645(Follistatin-like, N-terminal)|interpro:IPR006207(Cystine knot, C-terminal)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018097|interpro:IPR032675|mint:O94813|rcsb pdb:2V70|rcsb pdb:2V9S|rcsb pdb:2V9T|rcsb pdb:2WFH|reactome:R-HSA-373752|reactome:R-HSA-376176|reactome:R-HSA-428540|reactome:R-HSA-428542|reactome:R-HSA-428543|reactome:R-HSA-428890|reactome:R-HSA-8985586|reactome:R-HSA-9010553|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001611(Leucine-rich repeat)|ensembl:ENSG00000145147(gene)|ensembl:ENST00000504154(transcript)|go:"GO:0001657"(ureteric bud development)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0002689"(negative regulation of leukocyte chemotaxis)|go:"GO:0003180"(aortic valve morphogenesis) - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:QRksPL7aJniN+0thiLfIdeythoU9606 rogid:25Wc98dEfv1yROTD5pUtyQ+LWN89606 rigid:8y+U2NE6AQRbEBaf7V8QsUjTFuo false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94842 uniprotkb:P62140 intact:EBI-948613|ensembl:ENSP00000393080|ensembl:ENSP00000477868|intact:EBI-10965337|uniprotkb:B4DPY8|uniprotkb:E7EV69|uniprotkb:B4DSM0 intact:EBI-352350|uniprotkb:P37140|uniprotkb:Q5U087|uniprotkb:Q6FG45|uniprotkb:D6W565|uniprotkb:B2R5V4|ensembl:ENSP00000296122|ensembl:ENSP00000351298|ensembl:ENSP00000378769 psi-mi:tox4_human(display_long)|uniprotkb:Epidermal Langerhans cell protein LCP1(gene name synonym)|uniprotkb:TOX4(gene name)|psi-mi:TOX4(display_short)|uniprotkb:KIAA0737(gene name synonym)|uniprotkb:C14orf92(gene name synonym) psi-mi:pp1b_human(display_long)|uniprotkb:PPP1CB(gene name)|psi-mi:PPP1CB(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486049|imex:IM-26985-293 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000092203(gene)|ensembl:ENST00000448790(transcript)|ensembl:ENST00000613569(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|interpro:IPR037985|mint:O94842|refseq:NP_055643.1|refseq:NP_001290452.1 refseq:NP_002700.1|refseq:NP_996759.1|ensembl:ENSG00000213639(gene)|ensembl:ENST00000296122(transcript)|ensembl:ENST00000358506(transcript)|ensembl:ENST00000395366(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000165"(MAPK cascade)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0016791"(phosphatase activity)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042587"(glycogen granule)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0046872"(metal ion binding)|go:"GO:0050115"(myosin-light-chain-phosphatase activity)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|mint:P62140|reactome:R-HSA-163560|reactome:R-HSA-2173788|reactome:R-HSA-2565942|reactome:R-HSA-400253|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-5673000|reactome:R-HSA-9660537|dip:DIP-33220N - - comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:tiW0mcDNOr9TsvNLVZ+f36eiNpY9606 rogid:VtNJVyimeiEuRDDWtGswTqoSOH89606 rigid:BT7Ys7+RcdPl0n/P4mT1Yq0ncFI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94842 uniprotkb:P62136 intact:EBI-948613|ensembl:ENSP00000393080|ensembl:ENSP00000477868|intact:EBI-10965337|uniprotkb:B4DPY8|uniprotkb:E7EV69|uniprotkb:B4DSM0 intact:EBI-357253|uniprotkb:P08129|uniprotkb:P20653|uniprotkb:P22802|uniprotkb:B2R908|intact:EBI-2623163|uniprotkb:Q07161|intact:EBI-2556927|uniprotkb:A6NNR3|ensembl:ENSP00000365936 psi-mi:tox4_human(display_long)|uniprotkb:Epidermal Langerhans cell protein LCP1(gene name synonym)|uniprotkb:TOX4(gene name)|psi-mi:TOX4(display_short)|uniprotkb:KIAA0737(gene name synonym)|uniprotkb:C14orf92(gene name synonym) psi-mi:pp1a_human(display_long)|uniprotkb:PPP1CA(gene name)|psi-mi:PPP1CA(display_short)|uniprotkb:PPP1A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486049|imex:IM-26985-293 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000092203(gene)|ensembl:ENST00000448790(transcript)|ensembl:ENST00000613569(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|interpro:IPR037985|mint:O94842|refseq:NP_055643.1|refseq:NP_001290452.1 refseq:NP_001008709.1|refseq:NP_002699.1|refseq:NP_996756.1|dip:DIP-221N|dip:DIP-38195N|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0036496"(regulation of translational initiation by eIF2 alpha dephosphorylation)|go:"GO:0042587"(glycogen granule)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0051301"(cell division)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904886"(beta-catenin destruction complex disassembly)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|interpro:IPR037979|mint:P62136|rcsb pdb:3E7A|rcsb pdb:3E7B|rcsb pdb:3EGG|rcsb pdb:3EGH|rcsb pdb:3HVQ|rcsb pdb:3N5U|rcsb pdb:3V4Y|rcsb pdb:4G9J|rcsb pdb:4MOV|rcsb pdb:4MOY|rcsb pdb:4MP0|rcsb pdb:4XPN|rcsb pdb:5IOH|rcsb pdb:6ALZ|rcsb pdb:6CZO|rcsb pdb:6DCX|rcsb pdb:6DNO|rcsb pdb:6G0I|rcsb pdb:6G0J|rcsb pdb:6GHM|rcsb pdb:6OBN|rcsb pdb:6OBP|rcsb pdb:6OBQ|rcsb pdb:6OBR|rcsb pdb:6OBS|rcsb pdb:6OBU|rcsb pdb:6ZEE|rcsb pdb:6ZEF|rcsb pdb:6ZEG|rcsb pdb:6ZEH|rcsb pdb:6ZEI|rcsb pdb:6ZEJ|rcsb pdb:6ZK6|reactome:R-HSA-163560|reactome:R-HSA-180024|reactome:R-HSA-2173788|reactome:R-HSA-400253|go:"GO:0098793"(presynapse)|ensembl:ENSG00000172531(gene)|ensembl:ENST00000376745(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0030324"(lung development) - - comment:"author score: 32" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:tiW0mcDNOr9TsvNLVZ+f36eiNpY9606 rogid:IMypaKng+5AECbCd3N72pgzUlxQ9606 rigid:BT7Ys7+RcdPl0n/P4mT1Yq0ncFI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94842 uniprotkb:Q6UXN9 intact:EBI-948613|ensembl:ENSP00000393080|ensembl:ENSP00000477868|intact:EBI-10965337|uniprotkb:B4DPY8|uniprotkb:E7EV69|uniprotkb:B4DSM0 intact:EBI-1176082|uniprotkb:Q8TEB2|uniprotkb:A8K5R5|intact:EBI-2562464|ensembl:ENSP00000296490 psi-mi:tox4_human(display_long)|uniprotkb:Epidermal Langerhans cell protein LCP1(gene name synonym)|uniprotkb:TOX4(gene name)|psi-mi:TOX4(display_short)|uniprotkb:KIAA0737(gene name synonym)|uniprotkb:C14orf92(gene name synonym) psi-mi:wdr82_human(display_long)|uniprotkb:Protein TMEM113(gene name synonym)|uniprotkb:TMEM113(gene name synonym)|uniprotkb:WDR82(gene name)|psi-mi:WDR82(display_short)|uniprotkb:Swd2(gene name synonym)|uniprotkb:WDR82A(gene name synonym)|uniprotkb:UNQ9342/PRO34047(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486049|imex:IM-26985-293 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000092203(gene)|ensembl:ENST00000448790(transcript)|ensembl:ENST00000613569(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|interpro:IPR037985|mint:O94842|refseq:NP_055643.1|refseq:NP_001290452.1 refseq:NP_079498.2|ensembl:ENSG00000164091(gene)|ensembl:ENST00000296490(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005730"(nucleolus)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|interpro:IPR037867|mint:Q6UXN9 - - comment:"author score: 74" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:tiW0mcDNOr9TsvNLVZ+f36eiNpY9606 rogid:0TyKYwpTLd22Cm+ihT1+n0oo12c9606 rigid:BT7Ys7+RcdPl0n/P4mT1Yq0ncFI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O94842 uniprotkb:Q96QC0 intact:EBI-948613|ensembl:ENSP00000393080|ensembl:ENSP00000477868|intact:EBI-10965337|uniprotkb:B4DPY8|uniprotkb:E7EV69|uniprotkb:B4DSM0 intact:EBI-1210346|uniprotkb:O00405|ensembl:ENSP00000365694|ensembl:ENSP00000373080|ensembl:ENSP00000389299|ensembl:ENSP00000407181|ensembl:ENSP00000407310|ensembl:ENSP00000413554|ensembl:ENSP00000416060 psi-mi:tox4_human(display_long)|uniprotkb:Epidermal Langerhans cell protein LCP1(gene name synonym)|uniprotkb:TOX4(gene name)|psi-mi:TOX4(display_short)|uniprotkb:KIAA0737(gene name synonym)|uniprotkb:C14orf92(gene name synonym) psi-mi:pp1ra_human(display_long)|uniprotkb:PPP1R10(gene name)|psi-mi:PPP1R10(display_short)|uniprotkb:CAT53(gene name synonym)|uniprotkb:FB19(gene name synonym)|uniprotkb:PNUTS(gene name synonym)|uniprotkb:Phosphatase 1 nuclear targeting subunit(gene name synonym)|uniprotkb:MHC class I region proline-rich protein CAT53(gene name synonym)|uniprotkb:Protein FB19(gene name synonym)|uniprotkb:PP1-binding protein of 114 kDa(gene name synonym)|uniprotkb:p99(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486049|imex:IM-26985-293 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000092203(gene)|ensembl:ENST00000448790(transcript)|ensembl:ENST00000613569(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|interpro:IPR037985|mint:O94842|refseq:NP_055643.1|refseq:NP_001290452.1 refseq:XP_011513024.1|refseq:NP_002705.2|refseq:XP_006715193.1|refseq:XP_016866484.1|dip:DIP-39343N|ensembl:ENSG00000204569(gene)|ensembl:ENSG00000206489(gene)|ensembl:ENSG00000227804(gene)|ensembl:ENSG00000230995(gene)|ensembl:ENSG00000231737(gene)|ensembl:ENSG00000235291(gene)|ensembl:ENSG00000238104(gene)|ensembl:ENST00000376511(transcript)|ensembl:ENST00000383586(transcript)|ensembl:ENST00000420949(transcript)|ensembl:ENST00000424446(transcript)|ensembl:ENST00000426299(transcript)|ensembl:ENST00000429597(transcript)|ensembl:ENST00000449113(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0016604"(nuclear body)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0046872"(metal ion binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:1904290"(negative regulation of mitotic DNA damage checkpoint)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR017923|interpro:IPR035441|interpro:IPR036855|mint:Q96QC0|go:"GO:0000785"(chromatin) - - comment:"author score: 76" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:tiW0mcDNOr9TsvNLVZ+f36eiNpY9606 rogid:ZWueXxqNFYPT0WhbfYdR3d2H2G89606 rigid:BT7Ys7+RcdPl0n/P4mT1Yq0ncFI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95985 uniprotkb:P18754 intact:EBI-373403|uniprotkb:A0M8Q3|uniprotkb:Q9BUP5|ensembl:ENSP00000349705|ensembl:ENSP00000381773 intact:EBI-992720|uniprotkb:Q16269|uniprotkb:Q6NT97|ensembl:ENSP00000362939|ensembl:ENSP00000381931|ensembl:ENSP00000508074|ensembl:ENSP00000362938 psi-mi:top3b_human(display_long)|uniprotkb:TOP3B(gene name)|psi-mi:TOP3B(display_short)|uniprotkb:TOP3B1(gene name synonym)|uniprotkb:DNA topoisomerase III beta-1(gene name synonym) psi-mi:rcc1_human(display_long)|uniprotkb:Chromosome condensation protein 1(gene name synonym)|uniprotkb:Cell cycle regulatory protein(gene name synonym)|uniprotkb:RCC1(gene name)|psi-mi:RCC1(display_short)|uniprotkb:CHC1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485980|imex:IM-26985-373 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003926.1|refseq:XP_011528784.1|refseq:XP_006724412.1|refseq:XP_006724413.1|refseq:NP_001269041.1|refseq:NP_001269042.1|refseq:XP_005261868.1|ensembl:ENSG00000100038(gene)|ensembl:ENST00000357179(transcript)|ensembl:ENST00000398793(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003916"(DNA topoisomerase activity)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0005634"(nucleus)|go:"GO:0006265"(DNA topological change)|go:"GO:0007059"(chromosome segregation)|interpro:IPR000380(DNA topoisomerase, type IA, core)|interpro:IPR003601(DNA topoisomerase, type IA, domain 2)|interpro:IPR003602(DNA topoisomerase, type IA, DNA-binding)|interpro:IPR006171(TOPRIM)|interpro:IPR013825(DNA topoisomerase, type IA, central region, subdomain 2)|interpro:IPR013826(DNA topoisomerase, type IA, central region, subdomain 3)|interpro:IPR023405|interpro:IPR023406|interpro:IPR034144|mint:O95985|rcsb pdb:5GVC|rcsb pdb:5GVE|interpro:IPR013497(DNA topoisomerase, type IA, central)|interpro:IPR013824(DNA topoisomerase, type IA, central region, subdomain 1) refseq:NP_001041659.1|refseq:NP_001041660.1|refseq:NP_001041664.1|refseq:NP_001260.1|dip:DIP-35416N|ensembl:ENSG00000180198(gene)|ensembl:ENST00000373832(transcript)|ensembl:ENST00000373833(transcript)|ensembl:ENST00000398958(transcript)|ensembl:ENST00000683442(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000785"(chromatin)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0003682"(chromatin binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007084"(mitotic nuclear membrane reassembly)|go:"GO:0007088"(regulation of mitotic nuclear division)|go:"GO:0016032"(viral process)|rcsb pdb:5E1B|rcsb pdb:5E1D|rcsb pdb:5E1M|rcsb pdb:5E1O|rcsb pdb:5E2A|go:"GO:0031267"(small GTPase binding)|go:"GO:0031491"(nucleosome binding)|go:"GO:0031492"(nucleosomal DNA binding)|rcsb pdb:5E2B|rcsb pdb:5TBK|rcsb pdb:6DUB|reactome:R-HSA-165054|go:"GO:0031965"(nuclear membrane)|reactome:R-HSA-180746|reactome:R-HSA-9615933|go:"GO:0032991"(protein-containing complex)|go:"GO:0042393"(histone binding)|go:"GO:0043199"(sulfate binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|interpro:IPR000408(Regulator of chromosome condensation, RCC1)|interpro:IPR009091(Regulator of chromosome condensation/beta-lactamase-inhibitor protein II)|mint:P18754|rcsb pdb:1A12|rcsb pdb:1I2M - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:R4lom6gXvFXkkGF+Hj94m9ecsXA9606 rogid:/gP2xQp6fUffHTXpXvs8eb5YJ209606 rigid:76Pd27BfqhPcuFEzGwOoe0UMMS4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95985 uniprotkb:P53999 intact:EBI-373403|uniprotkb:A0M8Q3|uniprotkb:Q9BUP5|ensembl:ENSP00000349705|ensembl:ENSP00000381773 intact:EBI-998260|uniprotkb:Q96L29|ensembl:ENSP00000265073|ensembl:ENSP00000422078|ensembl:ENSP00000422806|ensembl:ENSP00000426850|ensembl:ENSP00000427100 psi-mi:top3b_human(display_long)|uniprotkb:TOP3B(gene name)|psi-mi:TOP3B(display_short)|uniprotkb:TOP3B1(gene name synonym)|uniprotkb:DNA topoisomerase III beta-1(gene name synonym) psi-mi:tcp4_human(display_long)|uniprotkb:SUB1 homolog(gene name synonym)|uniprotkb:Positive cofactor 4(gene name synonym)|uniprotkb:p14(gene name synonym)|uniprotkb:SUB1(gene name)|psi-mi:SUB1(display_short)|uniprotkb:PC4(gene name synonym)|uniprotkb:RPO2TC1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485980|imex:IM-26985-373 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003926.1|refseq:XP_011528784.1|refseq:XP_006724412.1|refseq:XP_006724413.1|refseq:NP_001269041.1|refseq:NP_001269042.1|refseq:XP_005261868.1|ensembl:ENSG00000100038(gene)|ensembl:ENST00000357179(transcript)|ensembl:ENST00000398793(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003916"(DNA topoisomerase activity)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0005634"(nucleus)|go:"GO:0006265"(DNA topological change)|go:"GO:0007059"(chromosome segregation)|interpro:IPR000380(DNA topoisomerase, type IA, core)|interpro:IPR003601(DNA topoisomerase, type IA, domain 2)|interpro:IPR003602(DNA topoisomerase, type IA, DNA-binding)|interpro:IPR006171(TOPRIM)|interpro:IPR013825(DNA topoisomerase, type IA, central region, subdomain 2)|interpro:IPR013826(DNA topoisomerase, type IA, central region, subdomain 3)|interpro:IPR023405|interpro:IPR023406|interpro:IPR034144|mint:O95985|rcsb pdb:5GVC|rcsb pdb:5GVE|interpro:IPR013497(DNA topoisomerase, type IA, central)|interpro:IPR013824(DNA topoisomerase, type IA, central region, subdomain 1) refseq:XP_011512246.1|ensembl:ENSG00000113387(gene)|ensembl:ENST00000265073(transcript)|ensembl:ENST00000502897(transcript)|ensembl:ENST00000506237(transcript)|ensembl:ENST00000512913(transcript)|ensembl:ENST00000515355(transcript)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003173(Transcriptional coactivator p15)|interpro:IPR009044(ssDNA-binding transcriptional regulator)|mint:P53999|rcsb pdb:1PCF|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|rcsb pdb:2C62|rcsb pdb:2PHE|rcsb pdb:4USG|go:"GO:0003697"(single-stranded DNA binding)|rcsb pdb:6YCS|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042802"(identical protein binding)|go:"GO:0051053"(negative regulation of DNA metabolic process)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060395"(SMAD protein signal transduction)|refseq:NP_006704.3|refseq:XP_016864475.1|refseq:XP_016864476.1|dip:DIP-29044N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:R4lom6gXvFXkkGF+Hj94m9ecsXA9606 rogid:FqBKBuLmQS+idbd68EdKsTCzPg89606 rigid:76Pd27BfqhPcuFEzGwOoe0UMMS4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95985 uniprotkb:Q96DI7 intact:EBI-373403|uniprotkb:A0M8Q3|uniprotkb:Q9BUP5|ensembl:ENSP00000349705|ensembl:ENSP00000381773 intact:EBI-538492|uniprotkb:O75938|uniprotkb:O95320|uniprotkb:B4DQJ1|ensembl:ENSP00000263694 psi-mi:top3b_human(display_long)|uniprotkb:TOP3B(gene name)|psi-mi:TOP3B(display_short)|uniprotkb:TOP3B1(gene name synonym)|uniprotkb:DNA topoisomerase III beta-1(gene name synonym) psi-mi:snr40_human(display_long)|uniprotkb:Prp8-binding protein(gene name synonym)|uniprotkb:U5 snRNP-specific 40 kDa protein(gene name synonym)|uniprotkb:38 kDa-splicing factor(gene name synonym)|uniprotkb:SNRNP40(gene name)|psi-mi:SNRNP40(display_short)|uniprotkb:PRP8BP(gene name synonym)|uniprotkb:SFP38(gene name synonym)|uniprotkb:WDR57(gene name synonym)|uniprotkb:WD repeat-containing protein 57(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485980|imex:IM-26985-373 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003926.1|refseq:XP_011528784.1|refseq:XP_006724412.1|refseq:XP_006724413.1|refseq:NP_001269041.1|refseq:NP_001269042.1|refseq:XP_005261868.1|ensembl:ENSG00000100038(gene)|ensembl:ENST00000357179(transcript)|ensembl:ENST00000398793(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003916"(DNA topoisomerase activity)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0005634"(nucleus)|go:"GO:0006265"(DNA topological change)|go:"GO:0007059"(chromosome segregation)|interpro:IPR000380(DNA topoisomerase, type IA, core)|interpro:IPR003601(DNA topoisomerase, type IA, domain 2)|interpro:IPR003602(DNA topoisomerase, type IA, DNA-binding)|interpro:IPR006171(TOPRIM)|interpro:IPR013825(DNA topoisomerase, type IA, central region, subdomain 2)|interpro:IPR013826(DNA topoisomerase, type IA, central region, subdomain 3)|interpro:IPR023405|interpro:IPR023406|interpro:IPR034144|mint:O95985|rcsb pdb:5GVC|rcsb pdb:5GVE|interpro:IPR013497(DNA topoisomerase, type IA, central)|interpro:IPR013824(DNA topoisomerase, type IA, central region, subdomain 1) refseq:NP_004805.2|ensembl:ENSG00000060688(gene)|ensembl:ENST00000263694(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005682"(U5 snRNP)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0071007"(U2-type catalytic step 2 spliceosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q96DI7|rcsb pdb:3JCR|rcsb pdb:5MQF|rcsb pdb:5O9Z|rcsb pdb:5XJC|rcsb pdb:5YZG|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6FF7|rcsb pdb:6ICZ|rcsb pdb:6ID0|rcsb pdb:6ID1|rcsb pdb:6QDV|rcsb pdb:6QW6|rcsb pdb:6QX9|rcsb pdb:6ZYM|rcsb pdb:7ABG|rcsb pdb:7ABI|rcsb pdb:7DVQ|reactome:R-HSA-72163|reactome:R-HSA-72165 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:R4lom6gXvFXkkGF+Hj94m9ecsXA9606 rogid:AfLoHYSy0MlW+OqHyEULLcpwQhQ9606 rigid:76Pd27BfqhPcuFEzGwOoe0UMMS4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95985 uniprotkb:Q9Y388 intact:EBI-373403|uniprotkb:A0M8Q3|uniprotkb:Q9BUP5|ensembl:ENSP00000349705|ensembl:ENSP00000381773 intact:EBI-7704044|ensembl:ENSP00000339090|intact:MINT-3085359|uniprotkb:Q5JY82|uniprotkb:Q9Y3I8|uniprotkb:A8K9Z0 psi-mi:top3b_human(display_long)|uniprotkb:TOP3B(gene name)|psi-mi:TOP3B(display_short)|uniprotkb:TOP3B1(gene name synonym)|uniprotkb:DNA topoisomerase III beta-1(gene name synonym) psi-mi:rbmx2_human(display_long)|uniprotkb:RBMX2(gene name)|psi-mi:RBMX2(display_short)|uniprotkb:CGI-79(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485980|imex:IM-26985-373 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003926.1|refseq:XP_011528784.1|refseq:XP_006724412.1|refseq:XP_006724413.1|refseq:NP_001269041.1|refseq:NP_001269042.1|refseq:XP_005261868.1|ensembl:ENSG00000100038(gene)|ensembl:ENST00000357179(transcript)|ensembl:ENST00000398793(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003916"(DNA topoisomerase activity)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0005634"(nucleus)|go:"GO:0006265"(DNA topological change)|go:"GO:0007059"(chromosome segregation)|interpro:IPR000380(DNA topoisomerase, type IA, core)|interpro:IPR003601(DNA topoisomerase, type IA, domain 2)|interpro:IPR003602(DNA topoisomerase, type IA, DNA-binding)|interpro:IPR006171(TOPRIM)|interpro:IPR013825(DNA topoisomerase, type IA, central region, subdomain 2)|interpro:IPR013826(DNA topoisomerase, type IA, central region, subdomain 3)|interpro:IPR023405|interpro:IPR023406|interpro:IPR034144|mint:O95985|rcsb pdb:5GVC|rcsb pdb:5GVE|interpro:IPR013497(DNA topoisomerase, type IA, central)|interpro:IPR013824(DNA topoisomerase, type IA, central region, subdomain 1) ensembl:ENSG00000134597(gene)|ensembl:ENST00000305536(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005686"(U2 snRNP)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0071011"(precatalytic spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:Q9Y388|rcsb pdb:5Z56|rcsb pdb:5Z57|rcsb pdb:5Z58|rcsb pdb:6FF4|rcsb pdb:6FF7|rcsb pdb:7ABH|rcsb pdb:7ABI|rcsb pdb:7DVQ|refseq:NP_057108.2 - - comment:mint|comment:homomint|comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:R4lom6gXvFXkkGF+Hj94m9ecsXA9606 rogid:dqOAjZdfWIiinV748tkfTJbLjwg9606 rigid:76Pd27BfqhPcuFEzGwOoe0UMMS4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95985 uniprotkb:Q92804 intact:EBI-373403|uniprotkb:A0M8Q3|uniprotkb:Q9BUP5|ensembl:ENSP00000349705|ensembl:ENSP00000381773 intact:EBI-2255091|uniprotkb:B2R837|uniprotkb:Q92751|intact:EBI-3867593|uniprotkb:Q86X94|ensembl:ENSP00000474096|ensembl:ENSP00000480040 psi-mi:top3b_human(display_long)|uniprotkb:TOP3B(gene name)|psi-mi:TOP3B(display_short)|uniprotkb:TOP3B1(gene name synonym)|uniprotkb:DNA topoisomerase III beta-1(gene name synonym) psi-mi:rbp56_human(display_long)|uniprotkb:TAF15(gene name)|psi-mi:TAF15(display_short)|uniprotkb:RBP56(gene name synonym)|uniprotkb:TAF2N(gene name synonym)|uniprotkb:RNA-binding protein 56(gene name synonym)|uniprotkb:68 kDa TATA-binding protein-associated factor(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485980|imex:IM-26985-373 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003926.1|refseq:XP_011528784.1|refseq:XP_006724412.1|refseq:XP_006724413.1|refseq:NP_001269041.1|refseq:NP_001269042.1|refseq:XP_005261868.1|ensembl:ENSG00000100038(gene)|ensembl:ENST00000357179(transcript)|ensembl:ENST00000398793(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003916"(DNA topoisomerase activity)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0005634"(nucleus)|go:"GO:0006265"(DNA topological change)|go:"GO:0007059"(chromosome segregation)|interpro:IPR000380(DNA topoisomerase, type IA, core)|interpro:IPR003601(DNA topoisomerase, type IA, domain 2)|interpro:IPR003602(DNA topoisomerase, type IA, DNA-binding)|interpro:IPR006171(TOPRIM)|interpro:IPR013825(DNA topoisomerase, type IA, central region, subdomain 2)|interpro:IPR013826(DNA topoisomerase, type IA, central region, subdomain 3)|interpro:IPR023405|interpro:IPR023406|interpro:IPR034144|mint:O95985|rcsb pdb:5GVC|rcsb pdb:5GVE|interpro:IPR013497(DNA topoisomerase, type IA, central)|interpro:IPR013824(DNA topoisomerase, type IA, central region, subdomain 1) refseq:NP_003478.1|refseq:NP_631961.1|dip:DIP-52760N|ensembl:ENSG00000270647(gene)|ensembl:ENSG00000276833(gene)|ensembl:ENST00000605844(transcript)|ensembl:ENST00000617382(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0048255"(mRNA stabilization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001876(Zinc finger, RanBP2-type)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034870|interpro:IPR034875|interpro:IPR035979|interpro:IPR036443|mint:Q92804|rcsb pdb:2MMY|reactome:R-HSA-167161|reactome:R-HSA-167162|reactome:R-HSA-167172|reactome:R-HSA-674695|reactome:R-HSA-6804756|reactome:R-HSA-73776|reactome:R-HSA-73779|reactome:R-HSA-75953|reactome:R-HSA-76042 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:R4lom6gXvFXkkGF+Hj94m9ecsXA9606 rogid:9+wyDu+1dvocxFI4GKvLqkvChDc9606 rigid:76Pd27BfqhPcuFEzGwOoe0UMMS4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95985 uniprotkb:P45973 intact:EBI-373403|uniprotkb:A0M8Q3|uniprotkb:Q9BUP5|ensembl:ENSP00000349705|ensembl:ENSP00000381773 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 psi-mi:top3b_human(display_long)|uniprotkb:TOP3B(gene name)|psi-mi:TOP3B(display_short)|uniprotkb:TOP3B1(gene name synonym)|uniprotkb:DNA topoisomerase III beta-1(gene name synonym) psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485980|imex:IM-26985-373 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003926.1|refseq:XP_011528784.1|refseq:XP_006724412.1|refseq:XP_006724413.1|refseq:NP_001269041.1|refseq:NP_001269042.1|refseq:XP_005261868.1|ensembl:ENSG00000100038(gene)|ensembl:ENST00000357179(transcript)|ensembl:ENST00000398793(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003916"(DNA topoisomerase activity)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0005634"(nucleus)|go:"GO:0006265"(DNA topological change)|go:"GO:0007059"(chromosome segregation)|interpro:IPR000380(DNA topoisomerase, type IA, core)|interpro:IPR003601(DNA topoisomerase, type IA, domain 2)|interpro:IPR003602(DNA topoisomerase, type IA, DNA-binding)|interpro:IPR006171(TOPRIM)|interpro:IPR013825(DNA topoisomerase, type IA, central region, subdomain 2)|interpro:IPR013826(DNA topoisomerase, type IA, central region, subdomain 3)|interpro:IPR023405|interpro:IPR023406|interpro:IPR034144|mint:O95985|rcsb pdb:5GVC|rcsb pdb:5GVE|interpro:IPR013497(DNA topoisomerase, type IA, central)|interpro:IPR013824(DNA topoisomerase, type IA, central region, subdomain 1) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:R4lom6gXvFXkkGF+Hj94m9ecsXA9606 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rigid:76Pd27BfqhPcuFEzGwOoe0UMMS4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95985 uniprotkb:P46087 intact:EBI-373403|uniprotkb:A0M8Q3|uniprotkb:Q9BUP5|ensembl:ENSP00000349705|ensembl:ENSP00000381773 intact:EBI-356811|uniprotkb:A1A4Z3|uniprotkb:Q0P5S5|uniprotkb:Q58F30|uniprotkb:B3KPD6|uniprotkb:Q05BA7|uniprotkb:Q3KQS4|ensembl:ENSP00000313272|ensembl:ENSP00000444437 psi-mi:top3b_human(display_long)|uniprotkb:TOP3B(gene name)|psi-mi:TOP3B(display_short)|uniprotkb:TOP3B1(gene name synonym)|uniprotkb:DNA topoisomerase III beta-1(gene name synonym) psi-mi:nop2_human(display_long)|uniprotkb:NOP2(gene name)|psi-mi:NOP2(display_short)|uniprotkb:NSUN1(gene name synonym)|uniprotkb:Proliferating-cell nucleolar antigen p120(gene name synonym)|uniprotkb:Proliferation-associated nucleolar protein p120(gene name synonym)|uniprotkb:NOL1(gene name synonym)|uniprotkb:Nucleolar protein 2 homolog(gene name synonym)|uniprotkb:Nucleolar protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485980|imex:IM-26985-373 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003926.1|refseq:XP_011528784.1|refseq:XP_006724412.1|refseq:XP_006724413.1|refseq:NP_001269041.1|refseq:NP_001269042.1|refseq:XP_005261868.1|ensembl:ENSG00000100038(gene)|ensembl:ENST00000357179(transcript)|ensembl:ENST00000398793(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003916"(DNA topoisomerase activity)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0005634"(nucleus)|go:"GO:0006265"(DNA topological change)|go:"GO:0007059"(chromosome segregation)|interpro:IPR000380(DNA topoisomerase, type IA, core)|interpro:IPR003601(DNA topoisomerase, type IA, domain 2)|interpro:IPR003602(DNA topoisomerase, type IA, DNA-binding)|interpro:IPR006171(TOPRIM)|interpro:IPR013825(DNA topoisomerase, type IA, central region, subdomain 2)|interpro:IPR013826(DNA topoisomerase, type IA, central region, subdomain 3)|interpro:IPR023405|interpro:IPR023406|interpro:IPR034144|mint:O95985|rcsb pdb:5GVC|rcsb pdb:5GVE|interpro:IPR013497(DNA topoisomerase, type IA, central)|interpro:IPR013824(DNA topoisomerase, type IA, central region, subdomain 1) refseq:NP_001028886.1|refseq:NP_006161.2|refseq:NP_001245237.1|refseq:NP_001245238.1|refseq:NP_001245239.1|refseq:XP_005253748.1|ensembl:ENSG00000111641(gene)|ensembl:ENST00000322166(transcript)|ensembl:ENST00000537442(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0001510"(RNA methylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009383"("rRNA (cytosine-C5-)-methyltransferase activity")|go:"GO:0070475"(rRNA base methylation)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR001678("Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p")|interpro:IPR011023(Nop2p)|interpro:IPR012586(P120R)|interpro:IPR018314|interpro:IPR023267|interpro:IPR023273|interpro:IPR029063|interpro:IPR031341|mint:P46087|reactome:R-HSA-6790901|reactome:R-HSA-8869496 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:R4lom6gXvFXkkGF+Hj94m9ecsXA9606 rogid:CvYaCDv8N8OvS0lPFy8jFEFaOTA9606 rigid:76Pd27BfqhPcuFEzGwOoe0UMMS4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95985 uniprotkb:Q9H7E2 intact:EBI-373403|uniprotkb:A0M8Q3|uniprotkb:Q9BUP5|ensembl:ENSP00000349705|ensembl:ENSP00000381773 intact:EBI-3938232|uniprotkb:Q6P992|uniprotkb:B2MWP9|uniprotkb:Q53XA6|ensembl:ENSP00000196169|ensembl:ENSP00000367126|ensembl:ENSP00000498191 psi-mi:top3b_human(display_long)|uniprotkb:TOP3B(gene name)|psi-mi:TOP3B(display_short)|uniprotkb:TOP3B1(gene name synonym)|uniprotkb:DNA topoisomerase III beta-1(gene name synonym) psi-mi:tdrd3_human(display_long)|uniprotkb:TDRD3(gene name)|psi-mi:TDRD3(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485980|imex:IM-26985-373 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003926.1|refseq:XP_011528784.1|refseq:XP_006724412.1|refseq:XP_006724413.1|refseq:NP_001269041.1|refseq:NP_001269042.1|refseq:XP_005261868.1|ensembl:ENSG00000100038(gene)|ensembl:ENST00000357179(transcript)|ensembl:ENST00000398793(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003916"(DNA topoisomerase activity)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0005634"(nucleus)|go:"GO:0006265"(DNA topological change)|go:"GO:0007059"(chromosome segregation)|interpro:IPR000380(DNA topoisomerase, type IA, core)|interpro:IPR003601(DNA topoisomerase, type IA, domain 2)|interpro:IPR003602(DNA topoisomerase, type IA, DNA-binding)|interpro:IPR006171(TOPRIM)|interpro:IPR013825(DNA topoisomerase, type IA, central region, subdomain 2)|interpro:IPR013826(DNA topoisomerase, type IA, central region, subdomain 3)|interpro:IPR023405|interpro:IPR023406|interpro:IPR034144|mint:O95985|rcsb pdb:5GVC|rcsb pdb:5GVE|interpro:IPR013497(DNA topoisomerase, type IA, central)|interpro:IPR013824(DNA topoisomerase, type IA, central region, subdomain 1) ensembl:ENSG00000083544(gene)|ensembl:ENST00000196169(transcript)|ensembl:ENST00000377894(transcript)|ensembl:ENST00000648252(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006325"(chromatin organization)|go:"GO:0035064"(methylated histone binding)|interpro:IPR002999(Tudor)|interpro:IPR009060(UBA-like)|interpro:IPR013894(Region of unknown function DUF1767)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR041915|interpro:IPR042470|mint:Q9H7E2|rcsb pdb:1WJI|rcsb pdb:2LTO|rcsb pdb:3PMT|rcsb pdb:3PNW|rcsb pdb:3S6W|rcsb pdb:5GVD|rcsb pdb:5GVE|rcsb pdb:5YJ8|rcsb pdb:6V9T|refseq:NP_001139542.1|refseq:NP_001139543.1|refseq:NP_110421.1|refseq:XP_016876266.1|dip:DIP-61935N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:R4lom6gXvFXkkGF+Hj94m9ecsXA9606 rogid:Fao3X109d50ZnSif4TMnx/seheA9606 rigid:76Pd27BfqhPcuFEzGwOoe0UMMS4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95985 uniprotkb:Q9NX58 intact:EBI-373403|uniprotkb:A0M8Q3|uniprotkb:Q9BUP5|ensembl:ENSP00000349705|ensembl:ENSP00000381773 intact:EBI-713507|uniprotkb:Q6FI78|uniprotkb:Q9NYS1|ensembl:ENSP00000345917|ensembl:ENSP00000397367|uniprotkb:D3DVS4 psi-mi:top3b_human(display_long)|uniprotkb:TOP3B(gene name)|psi-mi:TOP3B(display_short)|uniprotkb:TOP3B1(gene name synonym)|uniprotkb:DNA topoisomerase III beta-1(gene name synonym) psi-mi:lyar_human(display_long)|uniprotkb:LYAR(gene name)|psi-mi:LYAR(display_short)|uniprotkb:PNAS-5(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485980|imex:IM-26985-373 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003926.1|refseq:XP_011528784.1|refseq:XP_006724412.1|refseq:XP_006724413.1|refseq:NP_001269041.1|refseq:NP_001269042.1|refseq:XP_005261868.1|ensembl:ENSG00000100038(gene)|ensembl:ENST00000357179(transcript)|ensembl:ENST00000398793(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003916"(DNA topoisomerase activity)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0005634"(nucleus)|go:"GO:0006265"(DNA topological change)|go:"GO:0007059"(chromosome segregation)|interpro:IPR000380(DNA topoisomerase, type IA, core)|interpro:IPR003601(DNA topoisomerase, type IA, domain 2)|interpro:IPR003602(DNA topoisomerase, type IA, DNA-binding)|interpro:IPR006171(TOPRIM)|interpro:IPR013825(DNA topoisomerase, type IA, central region, subdomain 2)|interpro:IPR013826(DNA topoisomerase, type IA, central region, subdomain 3)|interpro:IPR023405|interpro:IPR023406|interpro:IPR034144|mint:O95985|rcsb pdb:5GVC|rcsb pdb:5GVE|interpro:IPR013497(DNA topoisomerase, type IA, central)|interpro:IPR013824(DNA topoisomerase, type IA, central region, subdomain 1) ensembl:ENSG00000145220(gene)|ensembl:ENST00000343470(transcript)|ensembl:ENST00000452476(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045824"(negative regulation of innate immune response)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0046872"(metal ion binding)|go:"GO:0048821"(erythrocyte development)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|interpro:IPR014898(Zinc finger, C2H2, LYAR-type)|interpro:IPR036236|interpro:IPR039999|interpro:IPR041010|mint:Q9NX58|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZVH|refseq:NP_001139197.1|refseq:NP_060286.1|refseq:XP_011511807.1|refseq:XP_011511808.1 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:R4lom6gXvFXkkGF+Hj94m9ecsXA9606 rogid:AJ+5B1LahcUlSWQehJ2vxY+8pwY9606 rigid:76Pd27BfqhPcuFEzGwOoe0UMMS4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95985 uniprotkb:P35268 intact:EBI-373403|uniprotkb:A0M8Q3|uniprotkb:Q9BUP5|ensembl:ENSP00000349705|ensembl:ENSP00000381773 intact:EBI-354533|intact:EBI-1055963|uniprotkb:Q6IBD1|uniprotkb:B2R495|ensembl:ENSP00000346088 psi-mi:top3b_human(display_long)|uniprotkb:TOP3B(gene name)|psi-mi:TOP3B(display_short)|uniprotkb:TOP3B1(gene name synonym)|uniprotkb:DNA topoisomerase III beta-1(gene name synonym) psi-mi:rl22_human(display_long)|uniprotkb:RPL22(gene name)|psi-mi:RPL22(display_short)|uniprotkb:Heparin-binding protein HBp15(gene name synonym)|uniprotkb:Epstein-Barr virus small RNA-associated protein(gene name synonym)|uniprotkb:EBER-associated protein(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL22(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485980|imex:IM-26985-373 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003926.1|refseq:XP_011528784.1|refseq:XP_006724412.1|refseq:XP_006724413.1|refseq:NP_001269041.1|refseq:NP_001269042.1|refseq:XP_005261868.1|ensembl:ENSG00000100038(gene)|ensembl:ENST00000357179(transcript)|ensembl:ENST00000398793(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003916"(DNA topoisomerase activity)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0005634"(nucleus)|go:"GO:0006265"(DNA topological change)|go:"GO:0007059"(chromosome segregation)|interpro:IPR000380(DNA topoisomerase, type IA, core)|interpro:IPR003601(DNA topoisomerase, type IA, domain 2)|interpro:IPR003602(DNA topoisomerase, type IA, DNA-binding)|interpro:IPR006171(TOPRIM)|interpro:IPR013825(DNA topoisomerase, type IA, central region, subdomain 2)|interpro:IPR013826(DNA topoisomerase, type IA, central region, subdomain 3)|interpro:IPR023405|interpro:IPR023406|interpro:IPR034144|mint:O95985|rcsb pdb:5GVC|rcsb pdb:5GVE|interpro:IPR013497(DNA topoisomerase, type IA, central)|interpro:IPR013824(DNA topoisomerase, type IA, central region, subdomain 1) refseq:NP_000974.1|ensembl:ENSG00000116251(gene)|ensembl:ENST00000234875(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0008201"(heparin binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0045182"(translation regulator activity)|go:"GO:0046632"(alpha-beta T cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099577"(regulation of translation at presynapse, modulating synaptic transmission)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002671(Ribosomal protein L22e)|interpro:IPR038526|mint:P35268|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|reactome:R-HSA-72706|rcsb pdb:6Z6L|rcsb pdb:6Z6M|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:R4lom6gXvFXkkGF+Hj94m9ecsXA9606 rogid:0TVillnqDkHmdTwxIedAJCVAdzY9606 rigid:76Pd27BfqhPcuFEzGwOoe0UMMS4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95985 uniprotkb:P06899 intact:EBI-373403|uniprotkb:A0M8Q3|uniprotkb:Q9BUP5|ensembl:ENSP00000349705|ensembl:ENSP00000381773 intact:EBI-6150252|uniprotkb:B2R4J4|uniprotkb:O60816|ensembl:ENSP00000342886|ensembl:ENSP00000476136 psi-mi:top3b_human(display_long)|uniprotkb:TOP3B(gene name)|psi-mi:TOP3B(display_short)|uniprotkb:TOP3B1(gene name synonym)|uniprotkb:DNA topoisomerase III beta-1(gene name synonym) psi-mi:h2b1j_human(display_long)|uniprotkb:H2BC11(gene name)|psi-mi:H2BC11(display_short)|uniprotkb:H2BFR(gene name synonym)|uniprotkb:HIST1H2BJ(gene name synonym)|uniprotkb:Histone H2B.1(gene name synonym)|uniprotkb:Histone H2B.r(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485980|imex:IM-26985-373 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003926.1|refseq:XP_011528784.1|refseq:XP_006724412.1|refseq:XP_006724413.1|refseq:NP_001269041.1|refseq:NP_001269042.1|refseq:XP_005261868.1|ensembl:ENSG00000100038(gene)|ensembl:ENST00000357179(transcript)|ensembl:ENST00000398793(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003916"(DNA topoisomerase activity)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0005634"(nucleus)|go:"GO:0006265"(DNA topological change)|go:"GO:0007059"(chromosome segregation)|interpro:IPR000380(DNA topoisomerase, type IA, core)|interpro:IPR003601(DNA topoisomerase, type IA, domain 2)|interpro:IPR003602(DNA topoisomerase, type IA, DNA-binding)|interpro:IPR006171(TOPRIM)|interpro:IPR013825(DNA topoisomerase, type IA, central region, subdomain 2)|interpro:IPR013826(DNA topoisomerase, type IA, central region, subdomain 3)|interpro:IPR023405|interpro:IPR023406|interpro:IPR034144|mint:O95985|rcsb pdb:5GVC|rcsb pdb:5GVE|interpro:IPR013497(DNA topoisomerase, type IA, central)|interpro:IPR013824(DNA topoisomerase, type IA, central region, subdomain 1) refseq:NP_066402.2|dip:DIP-421N|ensembl:ENSG00000124635(gene)|ensembl:ENST00000339812(transcript)|ensembl:ENST00000607124(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P06899|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WAA|rcsb pdb:3WTP|rcsb pdb:4CAY|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5FUG|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5VEY|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6JXD|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6YOV|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7K5X|rcsb pdb:3WA9|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:R4lom6gXvFXkkGF+Hj94m9ecsXA9606 rogid:74GQlSjGG1Ez6Uog74VXPLryKBc9606 rigid:76Pd27BfqhPcuFEzGwOoe0UMMS4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95985 uniprotkb:P05204 intact:EBI-373403|uniprotkb:A0M8Q3|uniprotkb:Q9BUP5|ensembl:ENSP00000349705|ensembl:ENSP00000381773 intact:EBI-1758689|uniprotkb:Q0VGD5|uniprotkb:Q6FGI5|uniprotkb:Q96C64|ensembl:ENSP00000355228|ensembl:ENSP00000481160 psi-mi:top3b_human(display_long)|uniprotkb:TOP3B(gene name)|psi-mi:TOP3B(display_short)|uniprotkb:TOP3B1(gene name synonym)|uniprotkb:DNA topoisomerase III beta-1(gene name synonym) psi-mi:hmgn2_human(display_long)|uniprotkb:HMGN2(gene name)|psi-mi:HMGN2(display_short)|uniprotkb:HMG17(gene name synonym)|uniprotkb:High mobility group nucleosome-binding domain-containing protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485980|imex:IM-26985-373 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003926.1|refseq:XP_011528784.1|refseq:XP_006724412.1|refseq:XP_006724413.1|refseq:NP_001269041.1|refseq:NP_001269042.1|refseq:XP_005261868.1|ensembl:ENSG00000100038(gene)|ensembl:ENST00000357179(transcript)|ensembl:ENST00000398793(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003916"(DNA topoisomerase activity)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0005634"(nucleus)|go:"GO:0006265"(DNA topological change)|go:"GO:0007059"(chromosome segregation)|interpro:IPR000380(DNA topoisomerase, type IA, core)|interpro:IPR003601(DNA topoisomerase, type IA, domain 2)|interpro:IPR003602(DNA topoisomerase, type IA, DNA-binding)|interpro:IPR006171(TOPRIM)|interpro:IPR013825(DNA topoisomerase, type IA, central region, subdomain 2)|interpro:IPR013826(DNA topoisomerase, type IA, central region, subdomain 3)|interpro:IPR023405|interpro:IPR023406|interpro:IPR034144|mint:O95985|rcsb pdb:5GVC|rcsb pdb:5GVE|interpro:IPR013497(DNA topoisomerase, type IA, central)|interpro:IPR013824(DNA topoisomerase, type IA, central region, subdomain 1) refseq:NP_005508.1|ensembl:ENSG00000198830(gene)|ensembl:ENST00000361427(transcript)|ensembl:ENST00000619352(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000079(High mobility group protein HMG14 and HMG17)|mint:P05204 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:R4lom6gXvFXkkGF+Hj94m9ecsXA9606 rogid:j8Khsp7BUJh0L9SicpVNR8LP6ZU9606 rigid:76Pd27BfqhPcuFEzGwOoe0UMMS4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95985 uniprotkb:O75475 intact:EBI-373403|uniprotkb:A0M8Q3|uniprotkb:Q9BUP5|ensembl:ENSP00000349705|ensembl:ENSP00000381773 intact:EBI-1801773|uniprotkb:O00256|uniprotkb:O95368|uniprotkb:Q6P391|uniprotkb:Q86YB9|uniprotkb:Q9NZI3|uniprotkb:Q9UER6|uniprotkb:D3DRI9|ensembl:ENSP00000370109|ensembl:ENSP00000370114 psi-mi:top3b_human(display_long)|uniprotkb:TOP3B(gene name)|psi-mi:TOP3B(display_short)|uniprotkb:TOP3B1(gene name synonym)|uniprotkb:DNA topoisomerase III beta-1(gene name synonym) psi-mi:psip1_human(display_long)|uniprotkb:PSIP1(gene name)|psi-mi:PSIP1(display_short)|uniprotkb:DFS70(gene name synonym)|uniprotkb:LEDGF(gene name synonym)|uniprotkb:PSIP2(gene name synonym)|uniprotkb:Lens epithelium-derived growth factor(gene name synonym)|uniprotkb:Transcriptional coactivator p75/p52(gene name synonym)|uniprotkb:Dense fine speckles 70 kDa protein(gene name synonym)|uniprotkb:CLL-associated antigen KW-7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485980|imex:IM-26985-373 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003926.1|refseq:XP_011528784.1|refseq:XP_006724412.1|refseq:XP_006724413.1|refseq:NP_001269041.1|refseq:NP_001269042.1|refseq:XP_005261868.1|ensembl:ENSG00000100038(gene)|ensembl:ENST00000357179(transcript)|ensembl:ENST00000398793(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003916"(DNA topoisomerase activity)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0005634"(nucleus)|go:"GO:0006265"(DNA topological change)|go:"GO:0007059"(chromosome segregation)|interpro:IPR000380(DNA topoisomerase, type IA, core)|interpro:IPR003601(DNA topoisomerase, type IA, domain 2)|interpro:IPR003602(DNA topoisomerase, type IA, DNA-binding)|interpro:IPR006171(TOPRIM)|interpro:IPR013825(DNA topoisomerase, type IA, central region, subdomain 2)|interpro:IPR013826(DNA topoisomerase, type IA, central region, subdomain 3)|interpro:IPR023405|interpro:IPR023406|interpro:IPR034144|mint:O95985|rcsb pdb:5GVC|rcsb pdb:5GVE|interpro:IPR013497(DNA topoisomerase, type IA, central)|interpro:IPR013824(DNA topoisomerase, type IA, central region, subdomain 1) refseq:NP_001304827.1|refseq:NP_001304829.1|refseq:NP_001121689.1|refseq:NP_066967.3|refseq:NP_150091.2|dip:DIP-46656N|ensembl:ENSG00000164985(gene)|ensembl:ENST00000380733(transcript)|ensembl:ENST00000380738(transcript)|go:"GO:0000395"(mRNA 5'-splice site recognition)|go:"GO:0000792"(heterochromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0009408"(response to heat)|go:"GO:0034399"(nuclear periphery)|go:"GO:0035327"|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0097100"(supercoiled DNA binding)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000313(PWWP)|interpro:IPR021567|interpro:IPR035441|interpro:IPR035496|interpro:IPR036218|mint:O75475|rcsb pdb:1Z9E|rcsb pdb:2B4J|rcsb pdb:2M16|rcsb pdb:2MSR|rcsb pdb:2MTN|rcsb pdb:2N3A|rcsb pdb:3F9K|rcsb pdb:3HPG|rcsb pdb:3HPH|rcsb pdb:3U88|rcsb pdb:3ZEH|rcsb pdb:4FU6|rcsb pdb:5N88|rcsb pdb:5OYM|rcsb pdb:5YI9|rcsb pdb:6EMO|rcsb pdb:6EMP|rcsb pdb:6EMQ|rcsb pdb:6EMR|rcsb pdb:6S01|rcsb pdb:6TRJ|rcsb pdb:6TVM|rcsb pdb:6Z2Y|reactome:R-HSA-162592|reactome:R-HSA-164843|reactome:R-HSA-175567|reactome:R-HSA-177539|reactome:R-HSA-180689|reactome:R-HSA-180910 - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:R4lom6gXvFXkkGF+Hj94m9ecsXA9606 rogid:MRtOw4kH/FxVku25dO5RQiNTjDA9606 rigid:76Pd27BfqhPcuFEzGwOoe0UMMS4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95985 uniprotkb:Q9BY77 intact:EBI-373403|uniprotkb:A0M8Q3|uniprotkb:Q9BUP5|ensembl:ENSP00000349705|ensembl:ENSP00000381773 intact:EBI-1776152|uniprotkb:Q5H972|uniprotkb:Q6PGN6|uniprotkb:Q7Z6Z0|uniprotkb:Q9NSP5|uniprotkb:Q9NSP6|uniprotkb:A8K6F8|uniprotkb:A8K6V9|uniprotkb:Q009A7|ensembl:ENSP00000252115 psi-mi:top3b_human(display_long)|uniprotkb:TOP3B(gene name)|psi-mi:TOP3B(display_short)|uniprotkb:TOP3B1(gene name synonym)|uniprotkb:DNA topoisomerase III beta-1(gene name synonym) psi-mi:pdip3_human(display_long)|uniprotkb:POLDIP3(gene name)|psi-mi:POLDIP3(display_short)|uniprotkb:KIAA1649(gene name synonym)|uniprotkb:PDIP46(gene name synonym)|uniprotkb:46 kDa DNA polymerase delta interaction protein(gene name synonym)|uniprotkb:S6K1 Aly/REF-like target(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485980|imex:IM-26985-373 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003926.1|refseq:XP_011528784.1|refseq:XP_006724412.1|refseq:XP_006724413.1|refseq:NP_001269041.1|refseq:NP_001269042.1|refseq:XP_005261868.1|ensembl:ENSG00000100038(gene)|ensembl:ENST00000357179(transcript)|ensembl:ENST00000398793(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003916"(DNA topoisomerase activity)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0005634"(nucleus)|go:"GO:0006265"(DNA topological change)|go:"GO:0007059"(chromosome segregation)|interpro:IPR000380(DNA topoisomerase, type IA, core)|interpro:IPR003601(DNA topoisomerase, type IA, domain 2)|interpro:IPR003602(DNA topoisomerase, type IA, DNA-binding)|interpro:IPR006171(TOPRIM)|interpro:IPR013825(DNA topoisomerase, type IA, central region, subdomain 2)|interpro:IPR013826(DNA topoisomerase, type IA, central region, subdomain 3)|interpro:IPR023405|interpro:IPR023406|interpro:IPR034144|mint:O95985|rcsb pdb:5GVC|rcsb pdb:5GVE|interpro:IPR013497(DNA topoisomerase, type IA, central)|interpro:IPR013824(DNA topoisomerase, type IA, central region, subdomain 1) refseq:NP_115687.2|refseq:NP_835237.1|ensembl:ENSG00000100227(gene)|ensembl:ENST00000252115(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0016607"(nuclear speck)|go:"GO:0016973"("poly(A)+ mRNA export from nucleus")|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045727"(positive regulation of translation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034784|interpro:IPR035979|mint:Q9BY77|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856 - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:R4lom6gXvFXkkGF+Hj94m9ecsXA9606 rogid:64+Bf4QpCDdKkZMMH/7afOnOKH09606 rigid:76Pd27BfqhPcuFEzGwOoe0UMMS4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95985 uniprotkb:P05114 intact:EBI-373403|uniprotkb:A0M8Q3|uniprotkb:Q9BUP5|ensembl:ENSP00000349705|ensembl:ENSP00000381773 intact:EBI-3915525|uniprotkb:Q3KQR8|ensembl:ENSP00000370125 psi-mi:top3b_human(display_long)|uniprotkb:TOP3B(gene name)|psi-mi:TOP3B(display_short)|uniprotkb:TOP3B1(gene name synonym)|uniprotkb:DNA topoisomerase III beta-1(gene name synonym) psi-mi:hmgn1_human(display_long)|uniprotkb:HMGN1(gene name)|psi-mi:HMGN1(display_short)|uniprotkb:HMG14(gene name synonym)|uniprotkb:High mobility group nucleosome-binding domain-containing protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485980|imex:IM-26985-373 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003926.1|refseq:XP_011528784.1|refseq:XP_006724412.1|refseq:XP_006724413.1|refseq:NP_001269041.1|refseq:NP_001269042.1|refseq:XP_005261868.1|ensembl:ENSG00000100038(gene)|ensembl:ENST00000357179(transcript)|ensembl:ENST00000398793(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003916"(DNA topoisomerase activity)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0005634"(nucleus)|go:"GO:0006265"(DNA topological change)|go:"GO:0007059"(chromosome segregation)|interpro:IPR000380(DNA topoisomerase, type IA, core)|interpro:IPR003601(DNA topoisomerase, type IA, domain 2)|interpro:IPR003602(DNA topoisomerase, type IA, DNA-binding)|interpro:IPR006171(TOPRIM)|interpro:IPR013825(DNA topoisomerase, type IA, central region, subdomain 2)|interpro:IPR013826(DNA topoisomerase, type IA, central region, subdomain 3)|interpro:IPR023405|interpro:IPR023406|interpro:IPR034144|mint:O95985|rcsb pdb:5GVC|rcsb pdb:5GVE|interpro:IPR013497(DNA topoisomerase, type IA, central)|interpro:IPR013824(DNA topoisomerase, type IA, central region, subdomain 1) refseq:NP_004956.5|ensembl:ENSG00000205581(gene)|ensembl:ENST00000380749(transcript)|go:"GO:0000720"(pyrimidine dimer repair by nucleotide-excision repair)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010224"(response to UV-B)|go:"GO:0010225"(response to UV-C)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0048597"(post-embryonic camera-type eye morphogenesis)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:1901666"(positive regulation of NAD+ ADP-ribosyltransferase activity)|interpro:IPR000079(High mobility group protein HMG14 and HMG17)|mint:P05114|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210 - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:R4lom6gXvFXkkGF+Hj94m9ecsXA9606 rogid:2Ns7EUwCgpj8Gj6uTuB1K6UZksc9606 rigid:76Pd27BfqhPcuFEzGwOoe0UMMS4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95985 uniprotkb:P68431 intact:EBI-373403|uniprotkb:A0M8Q3|uniprotkb:Q9BUP5|ensembl:ENSP00000349705|ensembl:ENSP00000381773 intact:EBI-79722|ensembl:ENSP00000352252|ensembl:ENSP00000358160|ensembl:ENSP00000366999|ensembl:ENSP00000480826|ensembl:ENSP00000482271|ensembl:ENSP00000483283|ensembl:ENSP00000484095|ensembl:ENSP00000484638|ensembl:ENSP00000484658|ensembl:ENSP00000484841|ensembl:ENSP00000489282|intact:EBI-1560041|uniprotkb:A0PJT7|uniprotkb:P02295|uniprotkb:P02296|uniprotkb:P16106|uniprotkb:Q6ISV8|uniprotkb:Q6NWP8|uniprotkb:Q6NWP9|uniprotkb:Q6NXU4|uniprotkb:Q71DJ3|uniprotkb:Q93081|uniprotkb:A5PLR1 psi-mi:top3b_human(display_long)|uniprotkb:TOP3B(gene name)|psi-mi:TOP3B(display_short)|uniprotkb:TOP3B1(gene name synonym)|uniprotkb:DNA topoisomerase III beta-1(gene name synonym) psi-mi:h31_human(display_long)|uniprotkb:H3FA(gene name synonym)|uniprotkb:H3FL(gene name synonym)|uniprotkb:H3FD(gene name synonym)|uniprotkb:H3FI(gene name synonym)|uniprotkb:H3FH(gene name synonym)|uniprotkb:H3FK(gene name synonym)|uniprotkb:H3FF(gene name synonym)|uniprotkb:H3FJ(gene name synonym)|uniprotkb:H3FB(gene name synonym)|uniprotkb:Histone H3/a(gene name synonym)|uniprotkb:Histone H3/b(gene name synonym)|uniprotkb:Histone H3/c(gene name synonym)|uniprotkb:Histone H3/d(gene name synonym)|uniprotkb:Histone H3/f(gene name synonym)|uniprotkb:Histone H3/h(gene name synonym)|uniprotkb:Histone H3/i(gene name synonym)|uniprotkb:Histone H3/j(gene name synonym)|uniprotkb:Histone H3/k(gene name synonym)|uniprotkb:Histone H3/l(gene name synonym)|uniprotkb:H3C1(gene name)|psi-mi:H3C1(display_short)|uniprotkb:HIST1H3A(gene name synonym)|uniprotkb:H3C2(gene name)|psi-mi:H3C2(display_short)|uniprotkb:HIST1H3B(gene name synonym)|uniprotkb:H3C3(gene name)|psi-mi:H3C3(display_short)|uniprotkb:H3FC HIST1H3C(gene name synonym)|uniprotkb:H3C4(gene name)|psi-mi:H3C4(display_short)|uniprotkb:HIST1H3D(gene name synonym)|uniprotkb:H3C6(gene name)|psi-mi:H3C6(display_short)|uniprotkb:HIST1H3E(gene name synonym)|uniprotkb:H3C7(gene name)|psi-mi:H3C7(display_short)|uniprotkb:HIST1H3F(gene name synonym)|uniprotkb:H3C8(gene name)|psi-mi:H3C8(display_short)|uniprotkb:HIST1H3G(gene name synonym)|uniprotkb:H3C10(gene name)|psi-mi:H3C10(display_short)|uniprotkb:HIST1H3H(gene name synonym)|uniprotkb:H3C11(gene name)|psi-mi:H3C11(display_short)|uniprotkb:HIST1H3I(gene name synonym)|uniprotkb:H3C12(gene name)|psi-mi:H3C12(display_short)|uniprotkb:HIST1H3J(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485980|imex:IM-26985-373 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003926.1|refseq:XP_011528784.1|refseq:XP_006724412.1|refseq:XP_006724413.1|refseq:NP_001269041.1|refseq:NP_001269042.1|refseq:XP_005261868.1|ensembl:ENSG00000100038(gene)|ensembl:ENST00000357179(transcript)|ensembl:ENST00000398793(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003916"(DNA topoisomerase activity)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0005634"(nucleus)|go:"GO:0006265"(DNA topological change)|go:"GO:0007059"(chromosome segregation)|interpro:IPR000380(DNA topoisomerase, type IA, core)|interpro:IPR003601(DNA topoisomerase, type IA, domain 2)|interpro:IPR003602(DNA topoisomerase, type IA, DNA-binding)|interpro:IPR006171(TOPRIM)|interpro:IPR013825(DNA topoisomerase, type IA, central region, subdomain 2)|interpro:IPR013826(DNA topoisomerase, type IA, central region, subdomain 3)|interpro:IPR023405|interpro:IPR023406|interpro:IPR034144|mint:O95985|rcsb pdb:5GVC|rcsb pdb:5GVE|interpro:IPR013497(DNA topoisomerase, type IA, central)|interpro:IPR013824(DNA topoisomerase, type IA, central region, subdomain 1) rcsb pdb:4TN7|rcsb pdb:4U68|rcsb pdb:4UP0|rcsb pdb:4UY4|rcsb pdb:4X3K|rcsb pdb:4Y6L|rcsb pdb:4YHP|rcsb pdb:4YHZ|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z0R|rcsb pdb:4Z2M|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:4QBS|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B31|rcsb pdb:5C11|rcsb pdb:5C13|rcsb pdb:5C3I|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5D6Y|rcsb pdb:5DAH|rcsb pdb:5FB0|rcsb pdb:5FB1|rcsb pdb:5FFV|rcsb pdb:5GH9|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5H6Q|rcsb pdb:5H6R|rcsb pdb:5HJB|rcsb pdb:5HJC|rcsb pdb:5HJD|rcsb pdb:5HYN|rcsb pdb:5IQL|rcsb pdb:5J3V|rcsb pdb:5J9S|rcsb pdb:5JHN|rcsb pdb:5JIN|rcsb pdb:5JIY|rcsb pdb:5JJ0|rcsb pdb:5B2J|rcsb pdb:5JRG|rcsb pdb:5KJH|rcsb pdb:5KJI|rcsb pdb:5KKL|rcsb pdb:5LUG|rcsb pdb:5M5G|rcsb pdb:5MR8|rcsb pdb:5NNC|rcsb pdb:5OY3|rcsb pdb:5SVX|rcsb pdb:5SVY|rcsb pdb:5SZB|rcsb pdb:5SZC|rcsb pdb:5T0K|rcsb pdb:5T0M|rcsb pdb:5T1G|rcsb pdb:5T1I|rcsb pdb:5T8R|rcsb pdb:5TBN|rcsb pdb:5TDR|rcsb pdb:5TDW|rcsb pdb:5U2J|rcsb pdb:5V21|rcsb pdb:5V22|rcsb pdb:5VA6|rcsb pdb:5VAB|rcsb pdb:5VGE|rcsb pdb:5VNB|rcsb pdb:5NND|rcsb pdb:5WLE|rcsb pdb:5WVO|rcsb pdb:5WXG|rcsb pdb:5WXH|rcsb pdb:5WYI|rcsb pdb:5X60|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5XFQ|rcsb pdb:5XFR|rcsb pdb:5XNV|rcsb pdb:5XTZ|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Y20|rcsb pdb:5Y2F|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:6AXJ|rcsb pdb:6AZE|rcsb pdb:6BHD|rcsb pdb:6BHE|rcsb pdb:6BHG|rcsb pdb:6BHH|rcsb pdb:6BHI|rcsb pdb:6D07|rcsb pdb:6D08|rcsb pdb:6E83|rcsb pdb:6E86|rcsb pdb:5WFC|rcsb pdb:6F6D|rcsb pdb:6HTS|rcsb pdb:6IEU|rcsb pdb:6IIS|rcsb pdb:6IIT|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6JXD|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6LS6|rcsb pdb:6LSD|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MIL|rcsb pdb:6MIM|rcsb pdb:6MIN|rcsb pdb:6MIO|rcsb pdb:6MIQ|rcsb pdb:6PA1|rcsb pdb:6PAG|rcsb pdb:6HKT|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2H|rcsb pdb:6V2K|rcsb pdb:6V3N|rcsb pdb:6V41|rcsb pdb:6V92|rcsb pdb:6VIL|rcsb pdb:6WAV|rcsb pdb:6WW4|rcsb pdb:6YIF|rcsb pdb:6YIH|rcsb pdb:6YOV|rcsb pdb:7BWD|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:6R92|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7DBP|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7KLR|rcsb pdb:7LYC|reactome:R-HSA-1266695|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|ensembl:ENSG00000197153(gene)|ensembl:ENSG00000197409(gene)|ensembl:ENSG00000273983(gene)|ensembl:ENSG00000274750(gene)|ensembl:ENSG00000275379(gene)|ensembl:ENSG00000275714(gene)|ensembl:ENSG00000277775(gene)|ensembl:ENSG00000278828(gene)|ensembl:ENSG00000286522(gene)|ensembl:ENSG00000287080(gene)|ensembl:ENST00000356476(transcript)|ensembl:ENST00000359303(transcript)|ensembl:ENST00000369163(transcript)|ensembl:ENST00000612966(transcript)|ensembl:ENST00000613854(transcript)|ensembl:ENST00000614378(transcript)|ensembl:ENST00000614911(transcript)|ensembl:ENST00000616365(transcript)|ensembl:ENST00000618052(transcript)|ensembl:ENST00000621411(transcript)|ensembl:ENST00000634733(transcript)|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-3247509|reactome:R-HSA-9710421|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0060968"(obsolete regulation of gene silencing)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|interpro:IPR009072(Histone-fold)|mint:P68431|rcsb pdb:1CS9|rcsb pdb:1CT6|rcsb pdb:1O9S|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|rcsb pdb:1Q3L|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|rcsb pdb:2B2T|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|rcsb pdb:2B2U|rcsb pdb:2B2V|rcsb pdb:2B2W|rcsb pdb:2C1J|rcsb pdb:2C1N|go:"GO:0016020"(membrane)|rcsb pdb:2CO0|rcsb pdb:2CV5|rcsb pdb:2FSA|rcsb pdb:2KWJ|rcsb pdb:2KWK|rcsb pdb:2L75|rcsb pdb:2LBM|rcsb pdb:2LGG|rcsb pdb:2M0O|reactome:R-HSA-983231|reactome:R-HSA-977225|rcsb pdb:2NDG|rcsb pdb:2OQ6|rcsb pdb:2OT7|rcsb pdb:2OX0|rcsb pdb:2RI7|rcsb pdb:2RR4|rcsb pdb:2UXN|rcsb pdb:2V85|rcsb pdb:2V89|rcsb pdb:2VNF|rcsb pdb:2VPG|rcsb pdb:2X0L|rcsb pdb:3A1B|rcsb pdb:2NDF|rcsb pdb:3AFA|rcsb pdb:3AVR|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3B95|rcsb pdb:3FDT|rcsb pdb:3KMT|rcsb pdb:3KQI|rcsb pdb:3LQI|rcsb pdb:3LQJ|rcsb pdb:3MP1|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O37|rcsb pdb:3QJ6|rcsb pdb:3RIG|rcsb pdb:3RIY|rcsb pdb:3SOU|rcsb pdb:3SOW|rcsb pdb:3U31|rcsb pdb:3U3D|rcsb pdb:3U4S|rcsb pdb:3U5N|rcsb pdb:3U5O|rcsb pdb:3AZK|rcsb pdb:3U5P|rcsb pdb:3UEE|rcsb pdb:3UEF|rcsb pdb:3UII|rcsb pdb:3UIK|rcsb pdb:3V43|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:3ZG6|rcsb pdb:3ZVY|rcsb pdb:4A0J|rcsb pdb:4A0N|rcsb pdb:4A7J|rcsb pdb:3UIG|rcsb pdb:4BD3|rcsb pdb:4C1Q|rcsb pdb:4F4U|rcsb pdb:4F56|rcsb pdb:4FWF|rcsb pdb:4HON|rcsb pdb:4I51|rcsb pdb:4L7X|rcsb pdb:4LK9|rcsb pdb:4LKA|rcsb pdb:4LLB|rcsb pdb:4LXL|rcsb pdb:4N4H|rcsb pdb:4QBQ|rcsb pdb:4QBR|refseq:NP_003520.1|refseq:NP_003521.2|refseq:NP_003522.1|refseq:NP_003523.1|refseq:NP_003524.1|refseq:NP_003525.1|refseq:NP_003526.1|refseq:NP_003527.1|refseq:NP_003528.1|refseq:NP_066298.1|dip:DIP-29371N - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:R4lom6gXvFXkkGF+Hj94m9ecsXA9606 rogid:ood0OohxZHuhsWZtO7U7GMc+LwM9606 rigid:76Pd27BfqhPcuFEzGwOoe0UMMS4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95985 uniprotkb:P84243 intact:EBI-373403|uniprotkb:A0M8Q3|uniprotkb:Q9BUP5|ensembl:ENSP00000349705|ensembl:ENSP00000381773 intact:EBI-120658|uniprotkb:P06351|uniprotkb:P33155|uniprotkb:Q5VV55|uniprotkb:Q5VV56|uniprotkb:Q66I33|uniprotkb:Q9V3W4|ensembl:ENSP00000254810|ensembl:ENSP00000355778|ensembl:ENSP00000355780|ensembl:ENSP00000355781|ensembl:ENSP00000465813|ensembl:ENSP00000466020|ensembl:ENSP00000468714|ensembl:ENSP00000499275|ensembl:ENSP00000499385|ensembl:ENSP00000499800 psi-mi:top3b_human(display_long)|uniprotkb:TOP3B(gene name)|psi-mi:TOP3B(display_short)|uniprotkb:TOP3B1(gene name synonym)|uniprotkb:DNA topoisomerase III beta-1(gene name synonym) psi-mi:h33_human(display_long)|uniprotkb:H3-3A(gene name)|psi-mi:H3-3A(display_short)|uniprotkb:H3-3B(gene name)|psi-mi:H3-3B(display_short)|uniprotkb:H3.3A(gene name synonym)|uniprotkb:H3.3B(gene name synonym)|uniprotkb:H3F3(gene name synonym)|uniprotkb:H3F3A(gene name synonym)|uniprotkb:H3F3B(gene name synonym)|uniprotkb:PP781(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485980|imex:IM-26985-373 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003926.1|refseq:XP_011528784.1|refseq:XP_006724412.1|refseq:XP_006724413.1|refseq:NP_001269041.1|refseq:NP_001269042.1|refseq:XP_005261868.1|ensembl:ENSG00000100038(gene)|ensembl:ENST00000357179(transcript)|ensembl:ENST00000398793(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003916"(DNA topoisomerase activity)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0005634"(nucleus)|go:"GO:0006265"(DNA topological change)|go:"GO:0007059"(chromosome segregation)|interpro:IPR000380(DNA topoisomerase, type IA, core)|interpro:IPR003601(DNA topoisomerase, type IA, domain 2)|interpro:IPR003602(DNA topoisomerase, type IA, DNA-binding)|interpro:IPR006171(TOPRIM)|interpro:IPR013825(DNA topoisomerase, type IA, central region, subdomain 2)|interpro:IPR013826(DNA topoisomerase, type IA, central region, subdomain 3)|interpro:IPR023405|interpro:IPR023406|interpro:IPR034144|mint:O95985|rcsb pdb:5GVC|rcsb pdb:5GVE|interpro:IPR013497(DNA topoisomerase, type IA, central)|interpro:IPR013824(DNA topoisomerase, type IA, central region, subdomain 1) refseq:NP_002098.1|refseq:NP_005315.1|rcsb pdb:4H9N|rcsb pdb:3QL9|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:3QLA|rcsb pdb:3QLC|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4L58|rcsb pdb:4N4I|rcsb pdb:3WTP|rcsb pdb:4O62|rcsb pdb:4QQ4|rcsb pdb:4TMP|rcsb pdb:4GNE|rcsb pdb:4GNF|rcsb pdb:4U7T|rcsb pdb:4GNG|rcsb pdb:4W5A|rcsb pdb:4GU0|rcsb pdb:4GUR|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:4GUS|rcsb pdb:4GY5|rcsb pdb:5DWQ|rcsb pdb:5DX0|rcsb pdb:5JA4|rcsb pdb:5JJY|ensembl:ENSG00000132475(gene)|ensembl:ENSG00000163041(gene)|rcsb pdb:5JLB|rcsb pdb:5KDM|rcsb pdb:5X7X|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6HGT|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6J9J|rcsb pdb:6PZV|rcsb pdb:6QXZ|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6U04|rcsb pdb:7A08|reactome:R-HSA-427413|rcsb pdb:7CIZ|reactome:R-HSA-5250924|reactome:R-HSA-5334118|rcsb pdb:7CJ0|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-983231|rcsb pdb:7CWH|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-427359|reactome:R-HSA-427389|ensembl:ENST00000254810(transcript)|ensembl:ENST00000366813(transcript)|ensembl:ENST00000366815(transcript)|ensembl:ENST00000366816(transcript)|ensembl:ENST00000586607(transcript)|ensembl:ENST00000587560(transcript)|ensembl:ENST00000589599(transcript)|ensembl:ENST00000655399(transcript)|ensembl:ENST00000661429(transcript)|ensembl:ENST00000666609(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P84243|rcsb pdb:2L43|rcsb pdb:3ASK|rcsb pdb:3ASL|rcsb pdb:3AV2|rcsb pdb:3JVK|rcsb pdb:3MUK|rcsb pdb:3MUL|dip:DIP-40046N - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:R4lom6gXvFXkkGF+Hj94m9ecsXA9606 rogid:cRqA5/IBNfIbbxAnbwLqzXip20I9606 rigid:76Pd27BfqhPcuFEzGwOoe0UMMS4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95985 uniprotkb:O75367 intact:EBI-373403|uniprotkb:A0M8Q3|uniprotkb:Q9BUP5|ensembl:ENSP00000349705|ensembl:ENSP00000381773 intact:EBI-2868511|uniprotkb:Q7Z5E3|uniprotkb:Q9UP96|uniprotkb:Q9H8P3|uniprotkb:Q503A8|uniprotkb:O75377|uniprotkb:Q96D41|ensembl:ENSP00000423563|ensembl:ENSP00000424971 psi-mi:top3b_human(display_long)|uniprotkb:TOP3B(gene name)|psi-mi:TOP3B(display_short)|uniprotkb:TOP3B1(gene name synonym)|uniprotkb:DNA topoisomerase III beta-1(gene name synonym) psi-mi:h2ay_human(display_long)|uniprotkb:MACROH2A1(gene name)|psi-mi:MACROH2A1(display_short)|uniprotkb:H2AFY(gene name synonym)|uniprotkb:Histone H2A.y(gene name synonym)|uniprotkb:Medulloblastoma antigen MU-MB-50.205(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485980|imex:IM-26985-373 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003926.1|refseq:XP_011528784.1|refseq:XP_006724412.1|refseq:XP_006724413.1|refseq:NP_001269041.1|refseq:NP_001269042.1|refseq:XP_005261868.1|ensembl:ENSG00000100038(gene)|ensembl:ENST00000357179(transcript)|ensembl:ENST00000398793(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003916"(DNA topoisomerase activity)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0005634"(nucleus)|go:"GO:0006265"(DNA topological change)|go:"GO:0007059"(chromosome segregation)|interpro:IPR000380(DNA topoisomerase, type IA, core)|interpro:IPR003601(DNA topoisomerase, type IA, domain 2)|interpro:IPR003602(DNA topoisomerase, type IA, DNA-binding)|interpro:IPR006171(TOPRIM)|interpro:IPR013825(DNA topoisomerase, type IA, central region, subdomain 2)|interpro:IPR013826(DNA topoisomerase, type IA, central region, subdomain 3)|interpro:IPR023405|interpro:IPR023406|interpro:IPR034144|mint:O95985|rcsb pdb:5GVC|rcsb pdb:5GVE|interpro:IPR013497(DNA topoisomerase, type IA, central)|interpro:IPR013824(DNA topoisomerase, type IA, central region, subdomain 1) refseq:XP_011542031.1|refseq:XP_011542032.1|refseq:NP_001035248.1|refseq:NP_004884.1|refseq:NP_613075.1|refseq:NP_613258.2|dip:DIP-44283N|ensembl:ENSG00000113648(gene)|ensembl:ENST00000510038(transcript)|ensembl:ENST00000511689(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000182"(rDNA binding)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0001740"(Barr body)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0007549"(dosage compensation)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0033128"(negative regulation of histone phosphorylation)|go:"GO:0034184"(positive regulation of maintenance of mitotic sister chromatid cohesion)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:1901837"(negative regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902750"(negative regulation of cell cycle G2/M phase transition)|go:"GO:1902882"(regulation of response to oxidative stress)|go:"GO:1902883"(negative regulation of response to oxidative stress)|go:"GO:1902884"(positive regulation of response to oxidative stress)|go:"GO:1903226"(positive regulation of endodermal cell differentiation)|go:"GO:1904815"(negative regulation of protein localization to chromosome, telomeric region)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|interpro:IPR002589(Appr-1-p processing)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR021171|interpro:IPR032454|interpro:IPR035796|interpro:IPR043472|mint:O75367|rcsb pdb:1U35|rcsb pdb:1ZR3|rcsb pdb:1ZR5|rcsb pdb:2F8N|rcsb pdb:2FXK|rcsb pdb:3HQH|rcsb pdb:3HSV|rcsb pdb:3IID|rcsb pdb:3IIF|rcsb pdb:3IVB|rcsb pdb:5IIT|rcsb pdb:5LNC|interpro:IPR002119(Histone H2A) - - comment:"author score: 27" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:R4lom6gXvFXkkGF+Hj94m9ecsXA9606 rogid:0FCoM0/4mTtnc7cPDUleKuZ3HgM9606 rigid:76Pd27BfqhPcuFEzGwOoe0UMMS4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95985 uniprotkb:O00479 intact:EBI-373403|uniprotkb:A0M8Q3|uniprotkb:Q9BUP5|ensembl:ENSP00000349705|ensembl:ENSP00000381773 intact:EBI-2867693|uniprotkb:Q53XL9|uniprotkb:B2R4I6|ensembl:ENSP00000366798 psi-mi:top3b_human(display_long)|uniprotkb:TOP3B(gene name)|psi-mi:TOP3B(display_short)|uniprotkb:TOP3B1(gene name synonym)|uniprotkb:DNA topoisomerase III beta-1(gene name synonym) psi-mi:hmgn4_human(display_long)|uniprotkb:HMGN4(gene name)|psi-mi:HMGN4(display_short)|uniprotkb:HMG17L3(gene name synonym)|uniprotkb:NHC(gene name synonym)|uniprotkb:Non-histone chromosomal protein HMG-17-like 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485980|imex:IM-26985-373 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003926.1|refseq:XP_011528784.1|refseq:XP_006724412.1|refseq:XP_006724413.1|refseq:NP_001269041.1|refseq:NP_001269042.1|refseq:XP_005261868.1|ensembl:ENSG00000100038(gene)|ensembl:ENST00000357179(transcript)|ensembl:ENST00000398793(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003916"(DNA topoisomerase activity)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0005634"(nucleus)|go:"GO:0006265"(DNA topological change)|go:"GO:0007059"(chromosome segregation)|interpro:IPR000380(DNA topoisomerase, type IA, core)|interpro:IPR003601(DNA topoisomerase, type IA, domain 2)|interpro:IPR003602(DNA topoisomerase, type IA, DNA-binding)|interpro:IPR006171(TOPRIM)|interpro:IPR013825(DNA topoisomerase, type IA, central region, subdomain 2)|interpro:IPR013826(DNA topoisomerase, type IA, central region, subdomain 3)|interpro:IPR023405|interpro:IPR023406|interpro:IPR034144|mint:O95985|rcsb pdb:5GVC|rcsb pdb:5GVE|interpro:IPR013497(DNA topoisomerase, type IA, central)|interpro:IPR013824(DNA topoisomerase, type IA, central region, subdomain 1) refseq:NP_006344.1|refseq:XP_016865660.1|refseq:XP_016865661.1|refseq:XP_016865662.1|ensembl:ENSG00000182952(gene)|ensembl:ENST00000377575(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006325"(chromatin organization)|go:"GO:0031492"(nucleosomal DNA binding)|interpro:IPR000079(High mobility group protein HMG14 and HMG17)|mint:O00479 - - comment:"author score: 30" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:R4lom6gXvFXkkGF+Hj94m9ecsXA9606 rogid:S+sGfUyPi8TfoLIBhSfTTAK9bfA9606 rigid:76Pd27BfqhPcuFEzGwOoe0UMMS4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95985 uniprotkb:Q8IUE6 intact:EBI-373403|uniprotkb:A0M8Q3|uniprotkb:Q9BUP5|ensembl:ENSP00000349705|ensembl:ENSP00000381773 intact:EBI-1642157|ensembl:ENSP00000332790 psi-mi:top3b_human(display_long)|uniprotkb:TOP3B(gene name)|psi-mi:TOP3B(display_short)|uniprotkb:TOP3B1(gene name synonym)|uniprotkb:DNA topoisomerase III beta-1(gene name synonym) psi-mi:h2a2b_human(display_long)|uniprotkb:H2AC21(gene name)|psi-mi:H2AC21(display_short)|uniprotkb:H2A-clustered histone 21(gene name synonym)|uniprotkb:HIST2H2AB(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485980|imex:IM-26985-373 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003926.1|refseq:XP_011528784.1|refseq:XP_006724412.1|refseq:XP_006724413.1|refseq:NP_001269041.1|refseq:NP_001269042.1|refseq:XP_005261868.1|ensembl:ENSG00000100038(gene)|ensembl:ENST00000357179(transcript)|ensembl:ENST00000398793(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003916"(DNA topoisomerase activity)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0005634"(nucleus)|go:"GO:0006265"(DNA topological change)|go:"GO:0007059"(chromosome segregation)|interpro:IPR000380(DNA topoisomerase, type IA, core)|interpro:IPR003601(DNA topoisomerase, type IA, domain 2)|interpro:IPR003602(DNA topoisomerase, type IA, DNA-binding)|interpro:IPR006171(TOPRIM)|interpro:IPR013825(DNA topoisomerase, type IA, central region, subdomain 2)|interpro:IPR013826(DNA topoisomerase, type IA, central region, subdomain 3)|interpro:IPR023405|interpro:IPR023406|interpro:IPR034144|mint:O95985|rcsb pdb:5GVC|rcsb pdb:5GVE|interpro:IPR013497(DNA topoisomerase, type IA, central)|interpro:IPR013824(DNA topoisomerase, type IA, central region, subdomain 1) refseq:NP_778235.1|ensembl:ENSG00000184270(gene)|ensembl:ENST00000331128(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:Q8IUE6|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-9609690|reactome:R-HSA-9610379 - - comment:"author score: 31" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:R4lom6gXvFXkkGF+Hj94m9ecsXA9606 rogid:1F8W3E3hVpwLzJsW/37w8XshfOE9606 rigid:76Pd27BfqhPcuFEzGwOoe0UMMS4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95985 uniprotkb:P58876 intact:EBI-373403|uniprotkb:A0M8Q3|uniprotkb:Q9BUP5|ensembl:ENSP00000349705|ensembl:ENSP00000381773 intact:EBI-4409942|ensembl:ENSP00000289316|ensembl:ENSP00000367008 psi-mi:top3b_human(display_long)|uniprotkb:TOP3B(gene name)|psi-mi:TOP3B(display_short)|uniprotkb:TOP3B1(gene name synonym)|uniprotkb:DNA topoisomerase III beta-1(gene name synonym) psi-mi:h2b1d_human(display_long)|uniprotkb:Histone H2B.b(gene name synonym)|uniprotkb:H2BC5(gene name)|psi-mi:H2BC5(display_short)|uniprotkb:H2B-clustered histone 5(gene name synonym)|uniprotkb:H2BFB(gene name synonym)|uniprotkb:HIRA-interacting protein 2(gene name synonym)|uniprotkb:HIRIP2(gene name synonym)|uniprotkb:HIST1H2BD(gene name synonym)|uniprotkb:Histone H2B.1 B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25485980|imex:IM-26985-373 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003926.1|refseq:XP_011528784.1|refseq:XP_006724412.1|refseq:XP_006724413.1|refseq:NP_001269041.1|refseq:NP_001269042.1|refseq:XP_005261868.1|ensembl:ENSG00000100038(gene)|ensembl:ENST00000357179(transcript)|ensembl:ENST00000398793(transcript)|go:"GO:0000793"(condensed chromosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003916"(DNA topoisomerase activity)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0005634"(nucleus)|go:"GO:0006265"(DNA topological change)|go:"GO:0007059"(chromosome segregation)|interpro:IPR000380(DNA topoisomerase, type IA, core)|interpro:IPR003601(DNA topoisomerase, type IA, domain 2)|interpro:IPR003602(DNA topoisomerase, type IA, DNA-binding)|interpro:IPR006171(TOPRIM)|interpro:IPR013825(DNA topoisomerase, type IA, central region, subdomain 2)|interpro:IPR013826(DNA topoisomerase, type IA, central region, subdomain 3)|interpro:IPR023405|interpro:IPR023406|interpro:IPR034144|mint:O95985|rcsb pdb:5GVC|rcsb pdb:5GVE|interpro:IPR013497(DNA topoisomerase, type IA, central)|interpro:IPR013824(DNA topoisomerase, type IA, central region, subdomain 1) refseq:NP_066407.1|refseq:NP_619790.1|ensembl:ENSG00000158373(gene)|ensembl:ENST00000289316(transcript)|ensembl:ENST00000377777(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P58876|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|go:"GO:0005634"(nucleus) - - comment:"author score: 38" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:R4lom6gXvFXkkGF+Hj94m9ecsXA9606 rogid:07VBw5MCphdkMydMOPSjVqpGriI9606 rigid:76Pd27BfqhPcuFEzGwOoe0UMMS4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UJ04 uniprotkb:Q9H3K6 intact:EBI-308511|ensembl:ENSP00000410943|uniprotkb:O94828|uniprotkb:Q96GW8|uniprotkb:B4DYQ2 intact:EBI-1642537|uniprotkb:A1L454|uniprotkb:A7YDY3|ensembl:ENSP00000331127|ensembl:ENSP00000498355 psi-mi:tsyl4_human(display_long)|uniprotkb:TSPYL4(gene name)|psi-mi:TSPYL4(display_short)|uniprotkb:KIAA0721(gene name synonym) psi-mi:bola2_human(display_long)|uniprotkb:BOLA2(gene name)|psi-mi:BOLA2(display_short)|uniprotkb:BOLA2B(gene name)|psi-mi:BOLA2B(display_short)|uniprotkb:BOLA2A(gene name synonym)|uniprotkb:My016(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486358|imex:IM-26985-593 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000187189(gene)|ensembl:ENST00000420283(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0042393"(histone binding)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q9UJ04|refseq:NP_067680.3 refseq:NP_001026997.1|refseq:NP_001034271.1|refseq:NP_001307508.1|refseq:XP_016855107.1|ensembl:ENSG00000169627(gene)|ensembl:ENSG00000183336(gene)|ensembl:ENST00000330978(transcript)|ensembl:ENST00000651894(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0044571"([2Fe-2S] cluster assembly)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0097428"(protein maturation by iron-sulfur cluster transfer)|interpro:IPR002634(BolA-like protein)|interpro:IPR036065|mint:Q9H3K6|reactome:R-HSA-8950505 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xcAq3OJVo+H+zV8Tq/wwdwthb3M9606 rogid:5TcFdmQcwx5trexmXkWp9Arn5zE9606 rigid:A3B+Za/U6vvNwl8NCTndXTQJHnI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UJ04 uniprotkb:Q96DG6 intact:EBI-308511|ensembl:ENSP00000410943|uniprotkb:O94828|uniprotkb:Q96GW8|uniprotkb:B4DYQ2 intact:EBI-1044268|uniprotkb:Q8TED6|uniprotkb:D3DTC7|ensembl:ENSP00000296658 psi-mi:tsyl4_human(display_long)|uniprotkb:TSPYL4(gene name)|psi-mi:TSPYL4(display_short)|uniprotkb:KIAA0721(gene name synonym) psi-mi:cmbl_human(display_long)|uniprotkb:CMBL(gene name)|psi-mi:CMBL(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486358|imex:IM-26985-593 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000187189(gene)|ensembl:ENST00000420283(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0042393"(histone binding)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q9UJ04|refseq:NP_067680.3 refseq:NP_620164.1|ensembl:ENSG00000164237(gene)|ensembl:ENST00000296658(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002925(Dienelactone hydrolase)|interpro:IPR029058|interpro:IPR042946|mint:Q96DG6|reactome:R-HSA-211945|refseq:XP_016864523.1|refseq:XP_016864524.1 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:xcAq3OJVo+H+zV8Tq/wwdwthb3M9606 rogid:nIOgS/jTgYbRXndPjCCMtqb0cHU9606 rigid:A3B+Za/U6vvNwl8NCTndXTQJHnI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H0U9 uniprotkb:Q8N0Z8 intact:EBI-2371049|uniprotkb:O75885|uniprotkb:Q5TFE6|ensembl:ENSP00000357597|ensembl:ENSP00000498597 intact:EBI-7825279|ensembl:ENSP00000368318|uniprotkb:B4DP76|intact:MINT-8052350|uniprotkb:Q5TA41 psi-mi:tsyl1_human(display_long)|uniprotkb:TSPYL1(gene name)|psi-mi:TSPYL1(display_short)|uniprotkb:TSPYL(gene name synonym) psi-mi:pusl1_human(display_long)|uniprotkb:PUSL1(gene name)|psi-mi:PUSL1(display_short)|uniprotkb:tRNA pseudouridylate synthase-like 1(gene name synonym)|uniprotkb:tRNA-uridine isomerase-like 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486322|imex:IM-26985-515 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003300.1|ensembl:ENSG00000189241(gene)|ensembl:ENST00000368608(transcript)|ensembl:ENST00000652202(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019899"(enzyme binding)|go:"GO:0042393"(histone binding)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q9H0U9 ensembl:ENSG00000169972(gene)|ensembl:ENST00000379031(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0009982"(pseudouridine synthase activity)|go:"GO:0031119"(tRNA pseudouridine synthesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR001406(tRNA pseudouridine synthase)|interpro:IPR020094|interpro:IPR020095|interpro:IPR020097|interpro:IPR020103|mint:Q8N0Z8|refseq:NP_699170.1 - - comment:mint|comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wo2DsKIGA3gDmomoBajtGRpQpTQ9606 rogid:vj5uJUn7ENAZyPHxu981q6+X3W49606 rigid:zH3mrutzubvsWWO5jqxUCLyCKVU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H0U9 uniprotkb:Q02878 intact:EBI-2371049|uniprotkb:O75885|uniprotkb:Q5TFE6|ensembl:ENSP00000357597|ensembl:ENSP00000498597 intact:EBI-359655|uniprotkb:Q2M3Q3|uniprotkb:Q8WW97|ensembl:ENSP00000202773|ensembl:ENSP00000403172 psi-mi:tsyl1_human(display_long)|uniprotkb:TSPYL1(gene name)|psi-mi:TSPYL1(display_short)|uniprotkb:TSPYL(gene name synonym) psi-mi:rl6_human(display_long)|uniprotkb:RPL6(gene name)|psi-mi:RPL6(display_short)|uniprotkb:TXREB1(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 107(gene name synonym)|uniprotkb:Neoplasm-related protein C140(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486322|imex:IM-26985-515 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003300.1|ensembl:ENSG00000189241(gene)|ensembl:ENST00000368608(transcript)|ensembl:ENST00000652202(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019899"(enzyme binding)|go:"GO:0042393"(histone binding)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q9H0U9 refseq:NP_000961.2|refseq:NP_001019833.1|ensembl:ENSG00000089009(gene)|ensembl:ENST00000202773(transcript)|ensembl:ENST00000424576(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR000915(Ribosomal protein L6E)|interpro:IPR005568(Ribosomal protein L6, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041997|mint:Q02878|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001307066.1|refseq:NP_001307067.1|refseq:NP_001307068.1|refseq:NP_001307069.1|refseq:NP_001307070.1|refseq:XP_016875270.1|refseq:XP_016875271.1|dip:DIP-27547N - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wo2DsKIGA3gDmomoBajtGRpQpTQ9606 rogid:Y7fx3ToInzucV2QmI8KLSdHxai09606 rigid:zH3mrutzubvsWWO5jqxUCLyCKVU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H0U9 uniprotkb:Q9NW13 intact:EBI-2371049|uniprotkb:O75885|uniprotkb:Q5TFE6|ensembl:ENSP00000357597|ensembl:ENSP00000498597 intact:EBI-2878099|ensembl:ENSP00000223073|uniprotkb:Q96CV3|uniprotkb:A4D100|uniprotkb:Q53H65|uniprotkb:B4DU52|uniprotkb:E9PDD9 psi-mi:tsyl1_human(display_long)|uniprotkb:TSPYL1(gene name)|psi-mi:TSPYL1(display_short)|uniprotkb:TSPYL(gene name synonym) psi-mi:rbm28_human(display_long)|uniprotkb:RBM28(gene name)|psi-mi:RBM28(display_short)|uniprotkb:RNA-binding motif protein 28(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486322|imex:IM-26985-515 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003300.1|ensembl:ENSG00000189241(gene)|ensembl:ENST00000368608(transcript)|ensembl:ENST00000652202(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019899"(enzyme binding)|go:"GO:0042393"(histone binding)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q9H0U9 go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:Q9NW13|reactome:R-HSA-6791226|go:"GO:0003723"(RNA binding)|ensembl:ENSG00000106344(gene)|ensembl:ENST00000223073(transcript)|refseq:NP_001159607.1|refseq:NP_060547.2 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wo2DsKIGA3gDmomoBajtGRpQpTQ9606 rogid:yIPQX+d5YQpq3gpdtBilOXJcUsg9606 rigid:zH3mrutzubvsWWO5jqxUCLyCKVU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H0U9 uniprotkb:P82930 intact:EBI-2371049|uniprotkb:O75885|uniprotkb:Q5TFE6|ensembl:ENSP00000357597|ensembl:ENSP00000498597 intact:EBI-1048516|uniprotkb:Q9BVI7|ensembl:ENSP00000380531 psi-mi:tsyl1_human(display_long)|uniprotkb:TSPYL1(gene name)|psi-mi:TSPYL1(display_short)|uniprotkb:TSPYL(gene name synonym) psi-mi:rt34_human(display_long)|uniprotkb:MRPS34(gene name)|psi-mi:MRPS34(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein mS34(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486322|imex:IM-26985-515 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003300.1|ensembl:ENSG00000189241(gene)|ensembl:ENST00000368608(transcript)|ensembl:ENST00000652202(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019899"(enzyme binding)|go:"GO:0042393"(histone binding)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q9H0U9 refseq:NP_001287829.1|refseq:NP_076425.1|ensembl:ENSG00000074071(gene)|ensembl:ENST00000397375(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR032053|mint:P82930|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wo2DsKIGA3gDmomoBajtGRpQpTQ9606 rogid:UTZkYPSJqThFKwoB7D5sH6g0zuc9606 rigid:zH3mrutzubvsWWO5jqxUCLyCKVU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H0U9 uniprotkb:Q9UNH7 intact:EBI-2371049|uniprotkb:O75885|uniprotkb:Q5TFE6|ensembl:ENSP00000357597|ensembl:ENSP00000498597 intact:EBI-949294|ensembl:ENSP00000355217|uniprotkb:Q9Y449|uniprotkb:C0H5W9 psi-mi:tsyl1_human(display_long)|uniprotkb:TSPYL1(gene name)|psi-mi:TSPYL1(display_short)|uniprotkb:TSPYL(gene name synonym) psi-mi:snx6_human(display_long)|uniprotkb:TRAF4-associated factor 2(gene name synonym)|uniprotkb:SNX6(gene name)|psi-mi:SNX6(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486322|imex:IM-26985-515 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003300.1|ensembl:ENSG00000189241(gene)|ensembl:ENST00000368608(transcript)|ensembl:ENST00000652202(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019899"(enzyme binding)|go:"GO:0042393"(histone binding)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q9H0U9 ensembl:ENSG00000129515(gene)|ensembl:ENST00000362031(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034452"(dynactin binding)|go:"GO:0034713"(type I transforming growth factor beta receptor binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0097422"(tubular endosome)|go:"GO:1904646"(cellular response to amyloid-beta)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0016241"(regulation of macroautophagy)|interpro:IPR028657|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030904"(retromer complex)|interpro:IPR036871|interpro:IPR042136|mint:Q9UNH7|go:"GO:0030905"(retromer, tubulation complex)|refseq:NP_067072.3|refseq:NP_689419.2|dip:DIP-37549N - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wo2DsKIGA3gDmomoBajtGRpQpTQ9606 rogid:s8v8IGvyXPOBPCxGgtSk42phQdA9606 rigid:zH3mrutzubvsWWO5jqxUCLyCKVU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H0U9 uniprotkb:Q9ULU4 intact:EBI-2371049|uniprotkb:O75885|uniprotkb:Q5TFE6|ensembl:ENSP00000357597|ensembl:ENSP00000498597 intact:EBI-765834|uniprotkb:Q13517|uniprotkb:Q4JJ94|uniprotkb:Q4JJ95|uniprotkb:Q5TH09|uniprotkb:Q6MZM1|uniprotkb:Q8WXC5|uniprotkb:Q9H1F3|uniprotkb:Q9H1F4|uniprotkb:Q9H1F5|uniprotkb:Q9H1L8|uniprotkb:Q9H1L9|uniprotkb:Q9H2G5|uniprotkb:Q9NYN3|uniprotkb:Q9UIX6|uniprotkb:Q2HXV7|uniprotkb:E1P5U5|uniprotkb:B7Z680|uniprotkb:Q2HXV2|uniprotkb:Q2HXV8|uniprotkb:Q2HXW0|uniprotkb:Q2HXW1|uniprotkb:Q2HXW2|uniprotkb:Q2HXV4|uniprotkb:Q2HXV9|uniprotkb:B3KVL2|uniprotkb:B7Z2A8|uniprotkb:B7Z3E0|uniprotkb:B7ZM62|uniprotkb:F5H0X3|uniprotkb:H7C0U2|uniprotkb:J3KPU3|uniprotkb:Q2HXV1|uniprotkb:Q2HXV3|uniprotkb:Q5TH11|ensembl:ENSP00000312237 psi-mi:tsyl1_human(display_long)|uniprotkb:TSPYL1(gene name)|psi-mi:TSPYL1(display_short)|uniprotkb:TSPYL(gene name synonym) psi-mi:pkcb1_human(display_long)|uniprotkb:Rack7(gene name synonym)|uniprotkb:Cutaneous T-cell lymphoma-associated antigen se14-3(gene name synonym)|uniprotkb:Zinc finger MYND domain-containing protein 8(gene name synonym)|uniprotkb:ZMYND8(gene name)|psi-mi:ZMYND8(display_short)|uniprotkb:KIAA1125(gene name synonym)|uniprotkb:RACK7(gene name synonym)|uniprotkb:PRKCBP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486322|imex:IM-26985-515 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003300.1|ensembl:ENSG00000189241(gene)|ensembl:ENST00000368608(transcript)|ensembl:ENST00000652202(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019899"(enzyme binding)|go:"GO:0042393"(histone binding)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q9H0U9 refseq:NP_036540.3|refseq:NP_898868.1|refseq:NP_898869.1|refseq:XP_011527053.1|refseq:NP_001268711.1|refseq:NP_001268706.1|refseq:NP_001268710.1|ensembl:ENST00000262975|ensembl:ENSP00000262975|ensembl:ENSP00000312237|ensembl:ENST00000352431|ensembl:ENSP00000335537|ensembl:ENST00000355972|ensembl:ENSP00000348246|ensembl:ENST00000360911|ensembl:ENSP00000354166|ensembl:ENST00000372023|ensembl:ENSP00000361093|ensembl:ENST00000396281|ensembl:ENSP00000379577|refseq:NP_001268702.1|refseq:NP_001268703.1|refseq:NP_001268704.1|refseq:NP_001268705.1|refseq:NP_001268707.1|refseq:NP_001268712.1|refseq:XP_005260417.1|refseq:XP_005260423.1|ensembl:ENST00000446994|ensembl:ENSP00000396725|ensembl:ENST00000458360|ensembl:ENSP00000392964|ensembl:ENST00000461685|ensembl:ENSP00000418210|ensembl:ENST00000471951|ensembl:ENSP00000420095|ensembl:ENST00000536340|ensembl:ENSP00000439800|ensembl:ENST00000540497|ensembl:ENSP00000443086|refseq:NP_001268713.1|refseq:XP_005260413.1|refseq:NP_001268700.1|refseq:NP_001268701.1|refseq:XP_006723825.1|refseq:XP_016883250.1|refseq:XP_016883256.1|refseq:XP_016883257.1|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1902897"(regulation of postsynaptic density protein 95 clustering)|go:"GO:1902952"(positive regulation of dendritic spine maintenance)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR021931|interpro:IPR035505|interpro:IPR036427|interpro:IPR037967|interpro:IPR044075|mint:Q9ULU4|rcsb pdb:4COS|rcsb pdb:5B73|rcsb pdb:5MQ4|go:"GO:0005654"(nucleoplasm)|rcsb pdb:5Y1Z|ensembl:ENSG00000101040(gene)|ensembl:ENST00000311275(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus) - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wo2DsKIGA3gDmomoBajtGRpQpTQ9606 rogid:z46jFcDnmKauE75GMeApPZmfdDM9606 rigid:zH3mrutzubvsWWO5jqxUCLyCKVU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H0U9 uniprotkb:O14641 intact:EBI-2371049|uniprotkb:O75885|uniprotkb:Q5TFE6|ensembl:ENSP00000357597|ensembl:ENSP00000498597 intact:EBI-740850|ensembl:ENSP00000005340|uniprotkb:Q53XM0|uniprotkb:D3DTN3 psi-mi:tsyl1_human(display_long)|uniprotkb:TSPYL1(gene name)|psi-mi:TSPYL1(display_short)|uniprotkb:TSPYL(gene name synonym) psi-mi:dvl2_human(display_long)|uniprotkb:DSH homolog 2(gene name synonym)|uniprotkb:DVL2(gene name)|psi-mi:DVL2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486322|imex:IM-26985-515 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003300.1|ensembl:ENSG00000189241(gene)|ensembl:ENST00000368608(transcript)|ensembl:ENST00000652202(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019899"(enzyme binding)|go:"GO:0042393"(histone binding)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q9H0U9 refseq:NP_004413.1|ensembl:ENSG00000004975(gene)|ensembl:ENST00000005340(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005109"(frizzled binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007379"(segment specification)|go:"GO:0007507"(heart development)|go:"GO:0016235"(aggresome)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022007"(convergent extension involved in neural plate elongation)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044340"(canonical Wnt signaling pathway involved in regulation of cell proliferation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0090103"(cochlea morphogenesis)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008341(Dishevelled-2 region)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:O14641|rcsb pdb:2REY|rcsb pdb:3CBX|rcsb pdb:3CBY|rcsb pdb:3CBZ|rcsb pdb:3CC0|rcsb pdb:4WIP|rcsb pdb:5LNP|rcsb pdb:5SUY|rcsb pdb:5SUZ|rcsb pdb:6IW3|rcsb pdb:6JCK|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-2028269|reactome:R-HSA-4086400|reactome:R-HSA-4608870|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5099900|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9673324|ensembl:ENSP00000005340|dip:DIP-34433N - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wo2DsKIGA3gDmomoBajtGRpQpTQ9606 rogid:2Vdc8oRnT4Mz/j+EXQXrL3AszOc9606 rigid:zH3mrutzubvsWWO5jqxUCLyCKVU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H0U9 uniprotkb:Q8N1G0 intact:EBI-2371049|uniprotkb:O75885|uniprotkb:Q5TFE6|ensembl:ENSP00000357597|ensembl:ENSP00000498597 intact:EBI-1210558|uniprotkb:Q68DQ8|uniprotkb:Q9H937|uniprotkb:Q9P2A7|uniprotkb:D3DV17|ensembl:ENSP00000319829|ensembl:ENSP00000336620 psi-mi:tsyl1_human(display_long)|uniprotkb:TSPYL1(gene name)|psi-mi:TSPYL1(display_short)|uniprotkb:TSPYL(gene name synonym) psi-mi:zn687_human(display_long)|uniprotkb:ZNF687(gene name)|psi-mi:ZNF687(display_short)|uniprotkb:KIAA1441(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486322|imex:IM-26985-515 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003300.1|ensembl:ENSG00000189241(gene)|ensembl:ENST00000368608(transcript)|ensembl:ENST00000652202(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019899"(enzyme binding)|go:"GO:0042393"(histone binding)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q9H0U9 refseq:NP_001291692.1|refseq:NP_065883.1|refseq:NP_001291693.1|refseq:XP_011508114.1|refseq:XP_011508115.1|ensembl:ENSG00000143373(gene)|ensembl:ENST00000324048(transcript)|ensembl:ENST00000336715(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|interpro:IPR041697|mint:Q8N1G0 - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wo2DsKIGA3gDmomoBajtGRpQpTQ9606 rogid:NR6q/E7oFHWVxeOkmRTyG6HKTvQ9606 rigid:zH3mrutzubvsWWO5jqxUCLyCKVU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H0U9 uniprotkb:Q9H2G4 intact:EBI-2371049|uniprotkb:O75885|uniprotkb:Q5TFE6|ensembl:ENSP00000357597|ensembl:ENSP00000498597 intact:EBI-947459|uniprotkb:O94799|uniprotkb:Q96DG7|uniprotkb:Q9BZW6|ensembl:ENSP00000364591 psi-mi:tsyl1_human(display_long)|uniprotkb:TSPYL1(gene name)|psi-mi:TSPYL1(display_short)|uniprotkb:TSPYL(gene name synonym) psi-mi:tsyl2_human(display_long)|uniprotkb:TSPYL2(gene name)|psi-mi:TSPYL2(display_short)|uniprotkb:Differentially-expressed nucleolar TGF-beta1 target protein(gene name synonym)|uniprotkb:Cell division autoantigen 1(gene name synonym)|uniprotkb:Cutaneous T-cell lymphoma-associated antigen se20-4(gene name synonym)|uniprotkb:Nuclear protein of 79 kDa(gene name synonym)|uniprotkb:CDA1(gene name synonym)|uniprotkb:DENTT(gene name synonym)|uniprotkb:TSPX(gene name synonym)|uniprotkb:HRIHFB2216(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486322|imex:IM-26985-515 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003300.1|ensembl:ENSG00000189241(gene)|ensembl:ENST00000368608(transcript)|ensembl:ENST00000652202(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019899"(enzyme binding)|go:"GO:0042393"(histone binding)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q9H0U9 refseq:NP_071400.1|ensembl:ENSP00000364591|ensembl:ENSG00000184205(gene)|ensembl:ENST00000375442(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042393"(histone binding)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045859"(regulation of protein kinase activity)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q9H2G4|reactome:R-HSA-381038 - - comment:"author score: 96" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wo2DsKIGA3gDmomoBajtGRpQpTQ9606 rogid:wVPRgfWOwBORcPzBZeyn9S9cqq09606 rigid:zH3mrutzubvsWWO5jqxUCLyCKVU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9H0U9 uniprotkb:Q9GZR7 intact:EBI-2371049|uniprotkb:O75885|uniprotkb:Q5TFE6|ensembl:ENSP00000357597|ensembl:ENSP00000498597 intact:EBI-713081|ensembl:ENSP00000481495|ensembl:ENSP00000482106|uniprotkb:E7EMJ4|uniprotkb:Q4V9L5 psi-mi:tsyl1_human(display_long)|uniprotkb:TSPYL1(gene name)|psi-mi:TSPYL1(display_short)|uniprotkb:TSPYL(gene name synonym) psi-mi:ddx24_human(display_long)|uniprotkb:DEAD box protein 24(gene name synonym)|uniprotkb:DDX24(gene name)|psi-mi:DDX24(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486322|imex:IM-26985-515 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003300.1|ensembl:ENSG00000189241(gene)|ensembl:ENST00000368608(transcript)|ensembl:ENST00000652202(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0019899"(enzyme binding)|go:"GO:0042393"(histone binding)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q9H0U9 ensembl:ENSG00000089737(gene)|ensembl:ENSG00000273761(gene)|ensembl:ENST00000613280(transcript)|ensembl:ENST00000621632(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR027417|mint:Q9GZR7|refseq:NP_065147.1|dip:DIP-47301N - - comment:"author score: 124" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:wo2DsKIGA3gDmomoBajtGRpQpTQ9606 rogid:n9gQabTC50Y/LtGMAMFNVgj12as9606 rigid:zH3mrutzubvsWWO5jqxUCLyCKVU false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:Q9UQ80 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-924893|uniprotkb:Q9UM59|uniprotkb:O43846|ensembl:ENSP00000302886 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:pa2g4_human(display_long)|uniprotkb:PA2G4(gene name)|psi-mi:PA2G4(display_short)|uniprotkb:Cell cycle protein p38-2G4 homolog(gene name synonym)|uniprotkb:ErbB3-binding protein 1(gene name synonym)|uniprotkb:EBP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_006182.2|dip:DIP-31275N|ensembl:ENSG00000170515(gene)|ensembl:ENST00000303305(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006364"(rRNA processing)|go:"GO:0006417"(regulation of translation)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000994(Peptidase M24, catalytic core)|interpro:IPR004545(Proliferation-associated protein 1)|interpro:IPR036005|interpro:IPR036388|interpro:IPR036390|mint:Q9UQ80|rcsb pdb:2Q8K|rcsb pdb:3J2I|rcsb pdb:6CHT|rcsb pdb:6LSR|rcsb pdb:6SXO|rcsb pdb:6WM8|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-6798695|interpro:IPR018349 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:OGRaz1uHilOnGXaAr/yeKMlCyns9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P04179 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-716989|intact:EBI-1058533|uniprotkb:P78434|uniprotkb:Q16792|uniprotkb:Q5TCM1|uniprotkb:Q96EE6|uniprotkb:Q9P2Z3|uniprotkb:B2R7R1|uniprotkb:E1P5A9|uniprotkb:B3KUK2|uniprotkb:B4E3K9|intact:EBI-11528264|uniprotkb:B4DL20|ensembl:ENSP00000356022|ensembl:ENSP00000446252 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:sodm_human(display_long)|uniprotkb:SOD2(gene name)|psi-mi:SOD2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_001019637.1|refseq:NP_000627.2|refseq:NP_001019636.1|refseq:NP_001309743.1|refseq:NP_001309744.1|refseq:NP_001309746.1|refseq:NP_001309748.1|refseq:NP_001309749.1|ensembl:ENSG00000112096(gene)|ensembl:ENST00000367055(transcript)|ensembl:ENST00000538183(transcript)|go:"GO:0000303"(response to superoxide)|go:"GO:0001315"(age-dependent response to reactive oxygen species)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003069"(acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure)|go:"GO:0003677"(DNA binding)|go:"GO:0004784"(superoxide dismutase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009314"(response to radiation)|go:"GO:0009409"(response to cold)|go:"GO:0010042"(response to manganese ion)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010729"(positive regulation of hydrogen peroxide biosynthetic process)|go:"GO:0014823"(response to activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0019825"(oxygen binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0032364"(oxygen homeostasis)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033591"(response to L-ascorbic acid)|go:"GO:0034021"(response to silicon dioxide)|go:"GO:0035900"(response to isolation stress)|go:"GO:0035902"(response to immobilization stress)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0042802"(identical protein binding)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0050665"(hydrogen peroxide biosynthetic process)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071000"(response to magnetism)|go:"GO:0071361"(cellular response to ethanol)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902631"(negative regulation of membrane hyperpolarization)|go:"GO:1904706"(negative regulation of vascular associated smooth muscle cell proliferation)|go:"GO:1905461"(positive regulation of vascular associated smooth muscle cell apoptotic process)|go:"GO:1905932"(positive regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching)|interpro:IPR001189(Manganese and iron superoxide dismutase)|interpro:IPR019831|interpro:IPR019832|interpro:IPR019833|interpro:IPR036314|interpro:IPR036324|mint:P04179|rcsb pdb:1AP5|rcsb pdb:1AP6|rcsb pdb:1EM1|rcsb pdb:1JA8|rcsb pdb:1LUV|rcsb pdb:1LUW|rcsb pdb:1MSD|rcsb pdb:1N0J|rcsb pdb:1N0N|rcsb pdb:1PL4|rcsb pdb:1PM9|rcsb pdb:1QNM|rcsb pdb:1SZX|rcsb pdb:1VAR|rcsb pdb:1XDC|rcsb pdb:1XIL|rcsb pdb:1ZTE|rcsb pdb:1ZUQ|rcsb pdb:2ADP|rcsb pdb:2ADQ|rcsb pdb:2GDS|rcsb pdb:2P4K|rcsb pdb:2QKA|rcsb pdb:2QKC|rcsb pdb:3C3S|rcsb pdb:3C3T|rcsb pdb:5GXO|rcsb pdb:5T30|rcsb pdb:5VF9|rcsb pdb:7KKS|rcsb pdb:7KKU|rcsb pdb:7KKW|rcsb pdb:7KLB|reactome:R-HSA-2151201|reactome:R-HSA-3299685|reactome:R-HSA-8862803|reactome:R-HSA-8950505|rcsb pdb:1ZSP|reactome:R-HSA-9615017 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:W5bvoLylgk4nEcm5peimceKIBbE9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P02765 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-1223374|uniprotkb:O14961|uniprotkb:O14962|uniprotkb:Q9P152|uniprotkb:A8K9N6|uniprotkb:B2R7G1|ensembl:ENSP00000393887 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:fetua_human(display_long)|uniprotkb:AHSG(gene name)|psi-mi:AHSG(display_short)|uniprotkb:FETUA(gene name synonym)|uniprotkb:PRO2743(orf name)|uniprotkb:Ba-alpha-2-glycoprotein(gene name synonym)|uniprotkb:Alpha-2-Z-globulin(gene name synonym)|uniprotkb:Fetuin-A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_001613.2|ensembl:ENSG00000145192(gene)|ensembl:ENST00000411641(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001503"(ossification)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006907"(pinocytosis)|go:"GO:0006953"(acute-phase response)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0019210"(kinase inhibitor activity)|go:"GO:0030500"(regulation of bone mineralization)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR001363(Proteinase inhibitor I25C, fetuin, conserved site)|interpro:IPR025760|mint:P02765|reactome:R-HSA-114608|reactome:R-HSA-381426|reactome:R-HSA-6798695|reactome:R-HSA-8957275 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:2SoUaMokkmtdRNazI9k95s9E9H49606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P60660 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-300817|uniprotkb:P16475|uniprotkb:P24572|uniprotkb:P24573|uniprotkb:Q12790|ensembl:ENSP00000446955|ensembl:ENSP00000448101|uniprotkb:Q6IAZ0|uniprotkb:Q6IPY5|uniprotkb:Q561V9 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:myl6_human(display_long)|uniprotkb:MYL6(gene name)|psi-mi:MYL6(display_short)|uniprotkb:Smooth muscle and nonmuscle myosin light chain alkali 6(gene name synonym)|uniprotkb:Myosin light chain alkali 3(gene name synonym)|uniprotkb:Myosin light chain 3(gene name synonym)|uniprotkb:17 kDa myosin light chain(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) ensembl:ENSG00000092841(gene)|ensembl:ENST00000548293(transcript)|ensembl:ENST00000550697(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0006936"(muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016020"(membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0031982"(vesicle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|mint:P60660|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-445355|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|refseq:NP_066299.2|refseq:NP_524147.2 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:LhE3NUqcuHlOla13C0vjnFZfzy89606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P30086 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-716384|uniprotkb:B2R4S1|ensembl:ENSP00000261313 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:pebp1_human(display_long)|uniprotkb:Prostatic-binding protein(gene name synonym)|uniprotkb:HCNPpp(gene name synonym)|uniprotkb:Neuropolypeptide h3(gene name synonym)|uniprotkb:Raf kinase inhibitor protein(gene name synonym)|uniprotkb:PEBP1(gene name)|psi-mi:PEBP1(display_short)|uniprotkb:PEBP(gene name synonym)|uniprotkb:PBP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_002558.1|ensembl:ENSG00000089220(gene)|ensembl:ENST00000261313(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001858(Phosphatidylethanolamine-binding, conserved site)|interpro:IPR008914(Phosphatidylethanolamine-binding protein PEBP)|interpro:IPR035810|interpro:IPR036610|mint:P30086|rcsb pdb:1BD9|rcsb pdb:1BEH|rcsb pdb:2L7W|rcsb pdb:2QYQ|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|dip:DIP-44269N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:6NY/YmyO5c8tNYfXtujwvP2chIc9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:Q99497 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-1164361|uniprotkb:O14805|uniprotkb:Q6DR95|uniprotkb:Q7LFU2|uniprotkb:B2R4Z1|ensembl:ENSP00000340278|ensembl:ENSP00000366708|ensembl:ENSP00000366711|ensembl:ENSP00000418770|ensembl:ENSP00000465404 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:park7_human(display_long)|uniprotkb:PARK7(gene name)|psi-mi:PARK7(display_short)|uniprotkb:Oncogene DJ1(gene name synonym)|uniprotkb:Parkinsonism-associated deglycase(gene name synonym)|uniprotkb:Maillard deglycase(gene name synonym)|uniprotkb:Protein DJ-1(gene name synonym)|uniprotkb:Protein/nucleic acid deglycase DJ-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_001116849.1|refseq:NP_009193.2|refseq:XP_005263481.1|go:"GO:0046295"(glycolate biosynthetic process)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050787"(detoxification of mercury ion)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051899"(membrane depolarization)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061727"(methylglyoxal catabolic process to lactate)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070994"(detection of oxidative stress)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098793"(presynapse)|go:"GO:0106044"(guanine deglycation)|go:"GO:0106045"(guanine deglycation, methylglyoxal removal)|go:"GO:0106046"(guanine deglycation, glyoxal removal)|go:"GO:0110095"(cellular detoxification of aldehyde)|go:"GO:0140041"(cellular detoxification of methylglyoxal)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901671"(positive regulation of superoxide dismutase activity)|go:"GO:1901984"(negative regulation of protein acetylation)|go:"GO:1902177"(positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902903"(regulation of supramolecular fiber organization)|go:"GO:1902958"(positive regulation of mitochondrial electron transport, NADH to ubiquinone)|go:"GO:1903073"(negative regulation of death-inducing signaling complex assembly)|go:"GO:1903094"(negative regulation of protein K48-linked deubiquitination)|go:"GO:1903122"(negative regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1903135"(cupric ion binding)|go:"GO:1903136"(cuprous ion binding)|go:"GO:1903168"(positive regulation of pyrroline-5-carboxylate reductase activity)|go:"GO:1903178"(positive regulation of tyrosine 3-monooxygenase activity)|go:"GO:1903181"(positive regulation of dopamine biosynthetic process)|go:"GO:1903189"(glyoxal metabolic process)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1903200"(positive regulation of L-dopa decarboxylase activity)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|go:"GO:1903208"(negative regulation of hydrogen peroxide-induced neuron death)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903384"(negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1905259"(negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990422"("glyoxalase (glycolic acid-forming) activity")|go:"GO:2000157"(negative regulation of ubiquitin-specific protease activity)|go:"GO:2000277"(positive regulation of oxidative phosphorylation uncoupler activity)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2000825"(positive regulation of androgen receptor activity)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001268"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR002818(ThiJ/PfpI)|interpro:IPR006287(DJ-1)|interpro:IPR029062|go:"GO:1903197"(positive regulation of L-dopa biosynthetic process)|rcsb pdb:3B36|rcsb pdb:3B38|rcsb pdb:3B3A|rcsb pdb:3BWE|rcsb pdb:3CY6|rcsb pdb:3CYF|rcsb pdb:3CZ9|rcsb pdb:3CZA|rcsb pdb:3EZG|mint:Q99497|rcsb pdb:1J42|rcsb pdb:1P5F|rcsb pdb:3F71|rcsb pdb:1PDV|rcsb pdb:1PDW|rcsb pdb:1PE0|rcsb pdb:1Q2U|rcsb pdb:3SF8|rcsb pdb:1SOA|rcsb pdb:1UCF|rcsb pdb:2OR3|rcsb pdb:2R1T|rcsb pdb:2R1U|rcsb pdb:2R1V|rcsb pdb:4BTE|rcsb pdb:2RK3|rcsb pdb:2RK4|rcsb pdb:2RK6|ensembl:ENSG00000116288(gene)|ensembl:ENST00000338639(transcript)|ensembl:ENST00000377488(transcript)|ensembl:ENST00000377491(transcript)|ensembl:ENST00000493678(transcript)|ensembl:ENST00000493373(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002866"(positive regulation of acute inflammatory response to antigenic stimulus)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006281"(DNA repair)|rcsb pdb:4MTC|rcsb pdb:4N0M|rcsb pdb:4N12|rcsb pdb:4OGF|rcsb pdb:4OQ4|rcsb pdb:4P2G|rcsb pdb:4P34|rcsb pdb:4P35|rcsb pdb:4P36|rcsb pdb:4RKW|rcsb pdb:4RKY|rcsb pdb:4S0Z|rcsb pdb:4ZGG|rcsb pdb:5IP5|rcsb pdb:5SY6|rcsb pdb:5SY9|rcsb pdb:5SYA|rcsb pdb:6AF5|rcsb pdb:6AF7|rcsb pdb:6AF9|rcsb pdb:6AFA|rcsb pdb:6AFB|rcsb pdb:6AFC|rcsb pdb:6AFD|rcsb pdb:6AFE|rcsb pdb:6AFF|rcsb pdb:6AFG|rcsb pdb:6AFH|rcsb pdb:6AFI|rcsb pdb:6AFJ|rcsb pdb:6AFL|rcsb pdb:6E5Z|rcsb pdb:6M8Z|rcsb pdb:7C62|reactome:R-HSA-3899300|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9646399|rcsb pdb:4MNT|go:"GO:0006517"(protein deglycosylation)|go:"GO:0006914"(autophagy)|go:"GO:0006954"(inflammatory response)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007338"(single fertilization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009438"(methylglyoxal metabolic process)|go:"GO:0010273"(detoxification of copper ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016532"(superoxide dismutase copper chaperone activity)|go:"GO:0016570"(histone modification)|go:"GO:0016605"(PML body)|go:"GO:0016684"(oxidoreductase activity, acting on peroxide as acceptor)|go:"GO:0019249"(lactate biosynthetic process)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0030424"(axon)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033864"("positive regulation of NAD(P)H oxidase activity")|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0036470"(tyrosine 3-monooxygenase activator activity)|go:"GO:0036471"(cellular response to glyoxal)|go:"GO:0036478"(L-dopa decarboxylase activator activity)|go:"GO:0036524"(protein deglycase activity)|go:"GO:0036526"(peptidyl-cysteine deglycation)|go:"GO:0036527"(peptidyl-arginine deglycation)|go:"GO:0036528"(peptidyl-lysine deglycation)|go:"GO:0036529"(protein deglycation, glyoxal removal)|go:"GO:0036530"(protein deglycation, methylglyoxal removal)|go:"GO:0036531"(glutathione deglycation)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042743"(hydrogen peroxide metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0030073"(insulin secretion)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045340"(mercury ion binding)|dip:DIP-35515N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:i5ah4UPCf+4cD51ClZNggMFJMDo9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P30044 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-722161|uniprotkb:Q14CK0|uniprotkb:Q6IAF2|uniprotkb:Q9UBU5|uniprotkb:Q9UJU4|uniprotkb:Q9UKX4|uniprotkb:A6NG06|uniprotkb:B7ZLJ4|uniprotkb:A6NC19|uniprotkb:B7ZVW3|ensembl:ENSP00000265462 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:prdx5_human(display_long)|uniprotkb:Peroxiredoxin V(gene name synonym)|uniprotkb:Peroxisomal antioxidant enzyme(gene name synonym)|uniprotkb:PLP(gene name synonym)|uniprotkb:Thioredoxin peroxidase PMP20(gene name synonym)|uniprotkb:Antioxidant enzyme B166(gene name synonym)|uniprotkb:TPx type VI(gene name synonym)|uniprotkb:Liver tissue 2D-page spot 71B(gene name synonym)|uniprotkb:Alu corepressor 1(gene name synonym)|uniprotkb:PRDX5(gene name)|psi-mi:PRDX5(display_short)|uniprotkb:ACR1(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 5(gene name synonym)|uniprotkb:SBBI10(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_036226.1|refseq:NP_857634.1|refseq:NP_857635.1|ensembl:ENSG00000126432(gene)|ensembl:ENST00000265462(transcript)|go:"GO:0001016"(RNA polymerase III transcription regulatory region sequence-specific DNA binding)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006954"(inflammatory response)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0016209"(antioxidant activity)|go:"GO:0016480"(negative regulation of transcription by RNA polymerase III)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032967"(positive regulation of collagen biosynthetic process)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043027"(cysteine-type endopeptidase inhibitor activity involved in apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051354"(negative regulation of oxidoreductase activity)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0060785"(regulation of apoptosis involved in tissue homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070995"(NADPH oxidation)|go:"GO:0072541"(peroxynitrite reductase activity)|go:"GO:2001057"(reactive nitrogen species metabolic process)|interpro:IPR013740(Redoxin)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249|interpro:IPR037944|mint:P30044|rcsb pdb:1H4O|rcsb pdb:1HD2|rcsb pdb:1OC3|rcsb pdb:1URM|rcsb pdb:2VL2|rcsb pdb:2VL3|rcsb pdb:2VL9|rcsb pdb:3MNG|rcsb pdb:4K7I|rcsb pdb:4K7N|rcsb pdb:4K7O|rcsb pdb:4MMM|reactome:R-HSA-3299685|reactome:R-HSA-5628897 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:Z1fs04RUXWI7z+s7Y+hzGige4mU9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P37802 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-1056740|intact:EBI-2825986|uniprotkb:Q5JRQ6|uniprotkb:Q5JRQ7|uniprotkb:Q9BUH5|uniprotkb:Q9H4P0|uniprotkb:Q6FGI1|uniprotkb:E9KL39|ensembl:ENSP00000357075|ensembl:ENSP00000357077 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:tagl2_human(display_long)|uniprotkb:TAGLN2(gene name)|psi-mi:TAGLN2(display_short)|uniprotkb:KIAA0120(gene name synonym)|uniprotkb:SM22-alpha homolog(gene name synonym)|uniprotkb:CDABP0035(orf name)|uniprotkb:Epididymis tissue protein Li 7e(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_003555.1|refseq:NP_001264152.1|refseq:NP_001264153.1|ensembl:ENSG00000158710(gene)|ensembl:ENST00000320307(transcript)|ensembl:ENST00000368097(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031982"(vesicle)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000557(Calponin repeat)|interpro:IPR001061("Transgelin (SM22-alpha)")|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR036872|mint:P37802|rcsb pdb:1WYM|reactome:R-HSA-114608 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:JxbMK5SbZWQd+XA9iYc/xuNaVQc9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P51858 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-3910118|uniprotkb:Q5SZ09|uniprotkb:D3DVC9|uniprotkb:Q5SZ07|uniprotkb:B3KU21|uniprotkb:Q5SZ08|ensembl:ENSP00000349878|ensembl:ENSP00000443120 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:hdgf_human(display_long)|uniprotkb:HDGF(gene name)|psi-mi:HDGF(display_short)|uniprotkb:HMG1L2(gene name synonym)|uniprotkb:High mobility group protein 1-like 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_001119522.1|refseq:NP_001119523.1|refseq:NP_004485.1|refseq:NP_001306115.1|refseq:NP_001306116.1|refseq:NP_001306117.1|ensembl:ENSG00000143321(gene)|ensembl:ENST00000357325(transcript)|ensembl:ENST00000537739(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000166"(nucleotide binding)|go:"GO:0001222"(transcription corepressor binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0008083"(growth factor activity)|go:"GO:0008201"(heparin binding)|go:"GO:0015631"(tubulin binding)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR000313(PWWP)|interpro:IPR035496|mint:P51858|rcsb pdb:1RI0|rcsb pdb:2NLU|reactome:R-HSA-381038 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:72uY+spcb4la5tJDUhHHtOn/Zrs9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P78417 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-712083|ensembl:ENSP00000358727|uniprotkb:Q5TA03|uniprotkb:Q7Z3T2|uniprotkb:D3DRA3|uniprotkb:F5H7H0 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:gsto1_human(display_long)|uniprotkb:GSTO1(gene name)|psi-mi:GSTO1(display_short)|uniprotkb:GSTTLP28(gene name synonym)|uniprotkb:Glutathione S-transferase omega 1-1(gene name synonym)|uniprotkb:Glutathione-dependent dehydroascorbate reductase(gene name synonym)|uniprotkb:Monomethylarsonic acid reductase(gene name synonym)|uniprotkb:"S-(Phenacyl)glutathione reductase"(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) ensembl:ENSG00000148834(gene)|ensembl:ENST00000369713(transcript)|go:"GO:0004364"(glutathione transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0014810"(positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0019852"(L-ascorbic acid metabolic process)|go:"GO:0042178"(xenobiotic catabolic process)|go:"GO:0045174"("glutathione dehydrogenase (ascorbate) activity")|go:"GO:0050610"(methylarsonate reductase activity)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071243"(cellular response to arsenic-containing substance)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR005442(Glutathione S-transferase, omega-class)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|rcsb pdb:1EEM|rcsb pdb:3LFL|rcsb pdb:3VLN|rcsb pdb:4IS0|rcsb pdb:4YQM|rcsb pdb:4YQU|rcsb pdb:4YQV|rcsb pdb:5UEH|rcsb pdb:5V3Q|rcsb pdb:5YVN|rcsb pdb:5YVO|rcsb pdb:6MHB|rcsb pdb:6MHC|rcsb pdb:6MHD|rcsb pdb:6PNM|rcsb pdb:6PNN|rcsb pdb:6PNO|reactome:R-HSA-156581|reactome:R-HSA-156590|reactome:R-HSA-196836|reactome:R-HSA-8950505|mint:P78417|refseq:NP_004823.1|refseq:NP_001177931.1|refseq:NP_001177932.1 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:nRO3PFh/+KXaNCPkTFSld+BQqD89606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:Q9H1E3 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-1390111|uniprotkb:Q5PXE7|uniprotkb:Q9H1D6|uniprotkb:Q9H723|uniprotkb:Q54AC0|ensembl:ENSP00000356110 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:nucks_human(display_long)|uniprotkb:P1(gene name synonym)|uniprotkb:NUCKS1(gene name)|psi-mi:NUCKS1(display_short)|uniprotkb:NUCKS(gene name synonym)|uniprotkb:JC7(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_073568.2|mint:Q9H1E3|interpro:IPR026633|ensembl:ENSG00000069275(gene)|ensembl:ENST00000367142(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000785"(chromatin)|go:"GO:0001678"(cellular glucose homeostasis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006275"(regulation of DNA replication)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0008134"(transcription factor binding)|go:"GO:0019046"(release from viral latency)|go:"GO:0031297"(replication fork processing)|go:"GO:0035822"(gene conversion)|go:"GO:0036297"(interstrand cross-link repair)|go:"GO:0043923"(positive regulation by host of viral transcription)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0060382"(regulation of DNA strand elongation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:1990968"(modulation by host of RNA binding by virus)|go:"GO:1990969"(modulation by host of viral RNA-binding transcription factor activity)|go:"GO:0005654"(nucleoplasm) - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:KYG9QwIUKWdRofCU7BAlbRdZe+Y9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P12277 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-357706|uniprotkb:Q2LE07|uniprotkb:A8K236|uniprotkb:B2R5R4|uniprotkb:Q6FG40|uniprotkb:Q9UC66|ensembl:ENSP00000299198 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:kcrb_human(display_long)|uniprotkb:CKB(gene name)|psi-mi:CKB(display_short)|uniprotkb:CKBB(gene name synonym)|uniprotkb:Creatine kinase B chain(gene name synonym)|uniprotkb:Brain creatine kinase(gene name synonym)|uniprotkb:Creatine phosphokinase B-type(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_001814.2|go:"GO:0005829"(cytosol)|ensembl:ENSG00000166165(gene)|ensembl:ENST00000348956(transcript)|go:"GO:0004111"(creatine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0016301"(kinase activity)|go:"GO:0021549"(cerebellum development)|interpro:IPR022413|interpro:IPR022414|interpro:IPR022415|interpro:IPR036802|mint:P12277|rcsb pdb:3B6R|rcsb pdb:3DRB|rcsb pdb:3DRE|rcsb pdb:6V9H|go:"GO:0021762"(substantia nigra development)|go:"GO:0030425"(dendrite)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0046314"(phosphocreatine biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000749("ATP:guanido phosphotransferase")|interpro:IPR014746(Glutamine synthetase/guanido kinase, catalytic region)|reactome:R-HSA-71288|reactome:R-HSA-9696264|dip:DIP-52968N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:WLRnU8sRUfJQoaPY0edGi9xiR+g9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:Q9Y266 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-357298|ensembl:ENSP00000319664|uniprotkb:Q5QP31|uniprotkb:Q5QP35|uniprotkb:Q9H0N2|uniprotkb:Q9Y2B6|intact:EBI-2555945 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:nudc_human(display_long)|uniprotkb:NUDC(gene name)|psi-mi:NUDC(display_short)|uniprotkb:Nuclear distribution protein C homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) ensembl:ENSG00000090273(gene)|ensembl:ENST00000321265(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0030496"(midbody)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR025934|interpro:IPR032572|interpro:IPR037898|mint:Q9Y266|rcsb pdb:3QOR|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|go:"GO:0007080"(mitotic metaphase plate congression)|reactome:R-HSA-9696270|refseq:NP_006591.1 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:e1Q+/+VhG73ljCc3+ibG+RZNQUM9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P67936 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-1642100|uniprotkb:P07226|uniprotkb:Q15659|uniprotkb:Q9BU85|uniprotkb:Q9H8Q3|uniprotkb:Q5U0D9|uniprotkb:Q9UCS1|uniprotkb:Q9UCS2|uniprotkb:Q9UCS3|uniprotkb:Q9UCS4|ensembl:ENSP00000495347 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:tpm4_human(display_long)|uniprotkb:TPM4(gene name)|psi-mi:TPM4(display_short)|uniprotkb:Tropomyosin-4(gene name synonym)|uniprotkb:TM30p1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_001138632.1|refseq:NP_003281.1|ensembl:ENSG00000167460(gene)|ensembl:ENST00000643579(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001725"(stress fiber)|go:"GO:0002102"(podosome)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005862"(muscle thin filament tropomyosin)|go:"GO:0005884"(actin filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016020"(membrane)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000533(Tropomyosin)|interpro:IPR014751(DNA double-strand break repair and VJ recombination XRCC4, C-terminal)|mint:P67936|reactome:R-HSA-390522|reactome:R-HSA-445355|reactome:R-HSA-9013424 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:o8bLltMHW3vvC7Tp6YpiC0M6lkw9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P37837 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-1056712|uniprotkb:O00751|uniprotkb:Q8WV32|uniprotkb:B2R8M2|uniprotkb:Q8WZ45|intact:EBI-28976584|ensembl:ENSP00000321259 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:taldo_human(display_long)|uniprotkb:TALDO1(gene name)|psi-mi:TALDO1(display_short)|uniprotkb:TAL(gene name synonym)|uniprotkb:TALDO(gene name synonym)|uniprotkb:TALDOR(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_006746.1|ensembl:ENSP00000321259|go:"GO:0005737"(cytoplasm)|ensembl:ENSG00000177156(gene)|ensembl:ENST00000319006(transcript)|go:"GO:0004801"(transaldolase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0009052"(pentose-phosphate shunt, non-oxidative branch)|go:"GO:0019682"(glyceraldehyde-3-phosphate metabolic process)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001585(Transaldolase)|interpro:IPR004730(Transaldolase AB)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR018225|mint:P37837|rcsb pdb:1F05|reactome:R-HSA-163754|reactome:R-HSA-6791055|reactome:R-HSA-6791462|reactome:R-HSA-71336|reactome:R-HSA-8950505 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:+guHJYtBM8f5qHDRdIbNZzs/Sl09606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:Q96DG6 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-1044268|uniprotkb:Q8TED6|uniprotkb:D3DTC7|ensembl:ENSP00000296658 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:cmbl_human(display_long)|uniprotkb:CMBL(gene name)|psi-mi:CMBL(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_620164.1|ensembl:ENSG00000164237(gene)|ensembl:ENST00000296658(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002925(Dienelactone hydrolase)|interpro:IPR029058|interpro:IPR042946|mint:Q96DG6|reactome:R-HSA-211945|refseq:XP_016864523.1|refseq:XP_016864524.1 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:nIOgS/jTgYbRXndPjCCMtqb0cHU9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:Q13838 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-348622|uniprotkb:B0S8C0|uniprotkb:Q5STB8|uniprotkb:O43496|uniprotkb:Q0EFA1|uniprotkb:Q2L6F9|uniprotkb:Q53GL9|uniprotkb:Q5RJ64|uniprotkb:Q5RJ66|uniprotkb:Q5ST94|uniprotkb:Q5STB4|uniprotkb:Q5STB5|uniprotkb:Q5STB7|uniprotkb:Q5STU4|uniprotkb:Q5STU5|uniprotkb:Q5STU6|uniprotkb:Q5STU8|uniprotkb:Q71V76|ensembl:ENSP00000373000|ensembl:ENSP00000379475|ensembl:ENSP00000383151|ensembl:ENSP00000383152|ensembl:ENSP00000387994|ensembl:ENSP00000388880|ensembl:ENSP00000390999|ensembl:ENSP00000391463|ensembl:ENSP00000393712|ensembl:ENSP00000394160|ensembl:ENSP00000398775|ensembl:ENSP00000399030|ensembl:ENSP00000400326|ensembl:ENSP00000404695|ensembl:ENSP00000405560|ensembl:ENSP00000407419|ensembl:ENSP00000411136|ensembl:ENSP00000411853|ensembl:ENSP00000416269 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:dx39b_human(display_long)|uniprotkb:UAP56(gene name synonym)|uniprotkb:DDX39B(gene name)|psi-mi:DDX39B(display_short)|uniprotkb:DEAD box protein UAP56(gene name synonym)|uniprotkb:56 kDa U2AF65-associated protein(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p47(gene name synonym)|uniprotkb:HLA-B-associated transcript 1 protein(gene name synonym)|uniprotkb:BAT1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_004631.1|refseq:NP_542165.1|ensembl:ENSG00000198563(gene)|ensembl:ENSG00000215425(gene)|ensembl:ENSG00000225073(gene)|ensembl:ENSG00000225859(gene)|ensembl:ENSG00000229496(gene)|ensembl:ENSG00000230624(gene)|ensembl:ENSG00000235439(gene)|ensembl:ENST00000383508(transcript)|ensembl:ENST00000396172(transcript)|ensembl:ENST00000400295(transcript)|ensembl:ENST00000400296(transcript)|ensembl:ENST00000412106(transcript)|ensembl:ENST00000412330(transcript)|ensembl:ENST00000413678(transcript)|ensembl:ENST00000414440(transcript)|ensembl:ENST00000415689(transcript)|ensembl:ENST00000416863(transcript)|ensembl:ENST00000430784(transcript)|ensembl:ENST00000431360(transcript)|ensembl:ENST00000441425(transcript)|ensembl:ENST00000445218(transcript)|ensembl:ENST00000448296(transcript)|ensembl:ENST00000453138(transcript)|ensembl:ENST00000456476(transcript)|ensembl:ENST00000456666(transcript)|ensembl:ENST00000458640(transcript)|go:"GO:0000245"(spliceosomal complex assembly)|go:"GO:0000346"(transcription export complex)|go:"GO:0001889"(liver development)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005687"(U4 snRNP)|go:"GO:0005688"(U6 snRNP)|go:"GO:0005737"(cytoplasm)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0008186"(ATP-dependent activity, acting on RNA)|go:"GO:0008380"(RNA splicing)|go:"GO:0010501"(RNA secondary structure unwinding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0017070"(U6 snRNA binding)|go:"GO:0030621"(U4 snRNA binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043008"(ATP-dependent protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046784"(viral mRNA export from host cell nucleus)|go:"GO:0061051"(positive regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904707"(positive regulation of vascular associated smooth muscle cell proliferation)|go:"GO:2000002"(negative regulation of DNA damage checkpoint)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:Q13838|rcsb pdb:1T5I|rcsb pdb:1T6N|rcsb pdb:1XTI|rcsb pdb:1XTJ|rcsb pdb:1XTK|rcsb pdb:7APK|reactome:R-HSA-159236|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-9013418 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:Cl/rf1oq31fZbLHC2foUXu9MBOE9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:Q15084 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-1043087|uniprotkb:Q6ZSH5|ensembl:ENSP00000272227|uniprotkb:B3KY95|uniprotkb:B5MCQ5|uniprotkb:B7Z4M8|uniprotkb:F8WA83|uniprotkb:B7Z254|uniprotkb:Q99778|uniprotkb:Q53RC7 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:pdia6_human(display_long)|uniprotkb:PDIA6(gene name)|psi-mi:PDIA6(display_short)|uniprotkb:TXNDC7(gene name synonym)|uniprotkb:Protein disulfide isomerase P5(gene name synonym)|uniprotkb:Thioredoxin domain-containing protein 7(gene name synonym)|uniprotkb:ERP5(gene name synonym)|uniprotkb:P5(gene name synonym)|uniprotkb:Endoplasmic reticulum protein 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_001269633.1|refseq:NP_001269634.1|refseq:NP_001269635.1|refseq:NP_001269636.1|interpro:IPR036249|interpro:IPR044569|mint:Q15084|rcsb pdb:1X5D|rcsb pdb:3VWW|rcsb pdb:3W8J|rcsb pdb:4EF0|rcsb pdb:4GWR|reactome:R-HSA-381038|reactome:R-HSA-381426|reactome:R-HSA-8957275|interpro:IPR017937|ensembl:ENSG00000143870(gene)|ensembl:ENST00000272227(transcript)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0042470"(melanosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|refseq:NP_005733.1 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:411bo7TdfeCtMvUqyBb7bofi5To9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:Q01469 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-1054073|uniprotkb:B2R4K0|ensembl:ENSP00000297258 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:fabp5_human(display_long)|uniprotkb:Epidermal-type fatty acid-binding protein(gene name synonym)|uniprotkb:Psoriasis-associated fatty acid-binding protein homolog(gene name synonym)|uniprotkb:FABP5(gene name)|psi-mi:FABP5(display_short)|uniprotkb:Fatty acid-binding protein, epidermal(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_001435.1|ensembl:ENSG00000164687(gene)|ensembl:ENST00000297258(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0005324"(long-chain fatty acid transporter activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0008289"(lipid binding)|go:"GO:0008544"(epidermis development)|go:"GO:0010829"(negative regulation of glucose transmembrane transport)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015909"(long-chain fatty acid transport)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0031392"(regulation of prostaglandin biosynthetic process)|go:"GO:0035360"(positive regulation of peroxisome proliferator activated receptor signaling pathway)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0045202"(synapse)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099178"(regulation of retrograde trans-synaptic signaling by endocanabinoid)|go:"GO:0120162"(positive regulation of cold-induced thermogenesis)|go:"GO:1990379"(lipid transport across blood-brain barrier)|interpro:IPR000463(Cytosolic fatty-acid binding)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR012674(Calycin)|interpro:IPR031259|mint:Q01469|rcsb pdb:1B56|rcsb pdb:1JJJ|rcsb pdb:4AZM|rcsb pdb:4AZR|rcsb pdb:4LKP|rcsb pdb:4LKT|rcsb pdb:5HZ5|rcsb pdb:5UR9|reactome:R-HSA-163560|reactome:R-HSA-5362517|reactome:R-HSA-6798695 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:vxp81/mezHcm5oo27QOmAM8Y5dI9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P23284 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-359252|uniprotkb:Q9BVK5|uniprotkb:A8K534|uniprotkb:Q6IBH5|ensembl:ENSP00000300026 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:ppib_human(display_long)|uniprotkb:PPIB(gene name)|psi-mi:PPIB(display_short)|uniprotkb:CYPB(gene name synonym)|uniprotkb:Cyclophilin B(gene name synonym)|uniprotkb:S-cyclophilin(gene name synonym)|uniprotkb:CYP-S1(gene name synonym)|uniprotkb:Rotamase B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_000933.1|ensembl:ENSG00000166794(gene)|ensembl:ENST00000300026(transcript)|go:"GO:0000413"(protein peptidyl-prolyl isomerization)|go:"GO:0003723"(RNA binding)|go:"GO:0003755"(peptidyl-prolyl cis-trans isomerase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0016018"(cyclosporin A binding)|go:"GO:0016020"(membrane)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042470"(melanosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0060348"(bone development)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070063"(RNA polymerase binding)|interpro:IPR002130(Peptidyl-prolyl cis-trans isomerase, cyclophilin-type)|interpro:IPR020892|interpro:IPR029000|mint:P23284|rcsb pdb:1CYN|rcsb pdb:3ICH|rcsb pdb:3ICI|reactome:R-HSA-1650814 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:h6nKaPUyEYUctYuu/3XfFhM4y9c9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P08758 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-296601|ensembl:ENSP00000296511|uniprotkb:Q6FI16|uniprotkb:Q8WV69|uniprotkb:Q6FHB3|uniprotkb:Q9UDH9|uniprotkb:D3DNW7 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:anxa5_human(display_long)|uniprotkb:ANXA5(gene name)|psi-mi:ANXA5(display_short)|uniprotkb:ANX5(gene name synonym)|uniprotkb:ENX2(gene name synonym)|uniprotkb:PP4(gene name synonym)|uniprotkb:Annexin-5(gene name synonym)|uniprotkb:Annexin V(gene name synonym)|uniprotkb:Lipocortin V(gene name synonym)|uniprotkb:Endonexin II(gene name synonym)|uniprotkb:Calphobindin I(gene name synonym)|uniprotkb:Placental anticoagulant protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein 4(gene name synonym)|uniprotkb:Thromboplastin inhibitor(gene name synonym)|uniprotkb:Vascular anticoagulant-alpha(gene name synonym)|uniprotkb:Anchorin CII(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) ensembl:ENSG00000164111(gene)|ensembl:ENST00000296511(transcript)|go:"GO:0004859"(phospholipase inhibitor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007596"(blood coagulation)|go:"GO:0016020"(membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0050819"(negative regulation of coagulation)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001464(Annexin)|interpro:IPR002392(Annexin, type V)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P08758|rcsb pdb:1ANW|rcsb pdb:1ANX|rcsb pdb:1AVH|rcsb pdb:1AVR|rcsb pdb:1HAK|rcsb pdb:1HVD|rcsb pdb:1HVE|rcsb pdb:1HVF|rcsb pdb:1HVG|rcsb pdb:1SAV|rcsb pdb:2XO2|rcsb pdb:2XO3|rcsb pdb:6K22|rcsb pdb:6K25|reactome:R-HSA-114608|refseq:NP_001145.1 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:vIp2wWkAz7uOtQSzbUJick5bT5o9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P31153 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-1050743|uniprotkb:Q53SP5|uniprotkb:A8K511|uniprotkb:D6W5L1|ensembl:ENSP00000303147|uniprotkb:B4DN45 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:metk2_human(display_long)|uniprotkb:Methionine adenosyltransferase 2(gene name synonym)|uniprotkb:Methionine adenosyltransferase II(gene name synonym)|uniprotkb:MAT2A(gene name)|psi-mi:MAT2A(display_short)|uniprotkb:AMS2(gene name synonym)|uniprotkb:MATA2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_005902.1|rcsb pdb:5A1G|rcsb pdb:5A1I|rcsb pdb:5UGH|rcsb pdb:6FAJ|rcsb pdb:6FBN|rcsb pdb:6FBO|rcsb pdb:6FBP|rcsb pdb:6FCB|rcsb pdb:6FCD|rcsb pdb:6FWB|ensembl:ENSG00000168906(gene)|ensembl:ENST00000306434(transcript)|go:"GO:0004478"(methionine adenosyltransferase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006556"(S-adenosylmethionine biosynthetic process)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0034214"(protein hexamerization)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048269"(methionine adenosyltransferase complex)|go:"GO:0051291"(protein heterooligomerization)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR002133(S-adenosylmethionine synthetase)|rcsb pdb:6G6R|rcsb pdb:6P9V|rcsb pdb:6WKB|interpro:IPR022628|rcsb pdb:7BHR|rcsb pdb:7BHS|interpro:IPR022629|interpro:IPR022630|interpro:IPR022631|interpro:IPR022636|mint:P31153|rcsb pdb:2P02|rcsb pdb:4KTT|rcsb pdb:4KTV|rcsb pdb:4NDN|rcsb pdb:5A19|rcsb pdb:7BHT|rcsb pdb:7BHU|rcsb pdb:7BHV|rcsb pdb:7BHW|rcsb pdb:7BHX|rcsb pdb:7KCC|rcsb pdb:7KCE|rcsb pdb:7KCF|rcsb pdb:7KDA|rcsb pdb:7KDB|rcsb pdb:7L1A|reactome:R-HSA-156581 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:8QDKkbuHcvQtfzy2XkVjCKjTK709606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P14625 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-359129|uniprotkb:Q96A97|ensembl:ENSP00000299767 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:enpl_human(display_long)|uniprotkb:HSP90B1(gene name)|psi-mi:HSP90B1(display_short)|uniprotkb:TRA1(gene name synonym)|uniprotkb:Heat shock protein 90 kDa beta member 1(gene name synonym)|uniprotkb:94 kDa glucose-regulated protein(gene name synonym)|uniprotkb:GRP94(gene name synonym)|uniprotkb:gp96 homolog(gene name synonym)|uniprotkb:Tumor rejection antigen 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_003290.1|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043666"(regulation of phosphoprotein phosphatase activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051208"(sequestering of calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0071682"(endocytic vesicle lumen)|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR020568|interpro:IPR020575|interpro:IPR036890|interpro:IPR037196|mint:P14625|rcsb pdb:4NH9|reactome:R-HSA-1679131|reactome:R-HSA-3000480|reactome:R-HSA-381183|reactome:R-HSA-381426|reactome:R-HSA-6785807|reactome:R-HSA-8957275|ensembl:ENSG00000166598(gene)|ensembl:ENST00000299767(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0003723"(RNA binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030496"(midbody)|go:"GO:0030970"(retrograde protein transport, ER to cytosol)|go:"GO:0031247"(actin rod assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|dip:DIP-36060N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:m5CdlplqVyMUWYe75aKDuMzztMY9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P20962 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-724050|ensembl:ENSP00000310088 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:ptms_human(display_long)|uniprotkb:PTMS(gene name)|psi-mi:PTMS(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_002815.3|ensembl:ENSG00000159335(gene)|ensembl:ENST00000309083(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005634"(nucleus)|go:"GO:0006260"(DNA replication)|interpro:IPR004931(Prothymosin/parathymosin)|mint:P20962 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:iELnzobQCJMa28yQCYCaO4h6/nE9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:Q92820 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-3045534|ensembl:ENSP00000260118 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:ggh_human(display_long)|uniprotkb:GGH(gene name)|psi-mi:GGH(display_short)|uniprotkb:Conjugase(gene name synonym)|uniprotkb:GH(gene name synonym)|uniprotkb:Gamma-Glu-X carboxypeptidase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) ensembl:ENSG00000137563(gene)|ensembl:ENST00000260118(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005773"(vacuole)|go:"GO:0005829"(cytosol)|go:"GO:0008238"(exopeptidase activity)|go:"GO:0008242"(omega peptidase activity)|go:"GO:0010043"(response to zinc ion)|go:"GO:0032868"(response to insulin)|go:"GO:0034722"(gamma-glutamyl-peptidase activity)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042470"(melanosome)|go:"GO:0042493"|go:"GO:0045471"(response to ethanol)|go:"GO:0046900"(tetrahydrofolylpolyglutamate metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070500"(poly-gamma-glutamate metabolic process)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR011697(Peptidase C26)|interpro:IPR015527(Peptidase C26, gamma-glutamyl hydrolase)|interpro:IPR029062|mint:Q92820|rcsb pdb:1L9X|reactome:R-HSA-6798695|refseq:NP_003869.1 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:QjPbv+fLXWnf6gmW2PsXVuyatR49606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P05114 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-3915525|uniprotkb:Q3KQR8|ensembl:ENSP00000370125 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:hmgn1_human(display_long)|uniprotkb:HMGN1(gene name)|psi-mi:HMGN1(display_short)|uniprotkb:HMG14(gene name synonym)|uniprotkb:High mobility group nucleosome-binding domain-containing protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_004956.5|ensembl:ENSG00000205581(gene)|ensembl:ENST00000380749(transcript)|go:"GO:0000720"(pyrimidine dimer repair by nucleotide-excision repair)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006283"(transcription-coupled nucleotide-excision repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010224"(response to UV-B)|go:"GO:0010225"(response to UV-C)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032786"(positive regulation of DNA-templated transcription, elongation)|go:"GO:0040034"(regulation of development, heterochronic)|go:"GO:0048597"(post-embryonic camera-type eye morphogenesis)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:1901666"(positive regulation of NAD+ ADP-ribosyltransferase activity)|interpro:IPR000079(High mobility group protein HMG14 and HMG17)|mint:P05114|reactome:R-HSA-6781823|reactome:R-HSA-6781827|reactome:R-HSA-6782135|reactome:R-HSA-6782210 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:2Ns7EUwCgpj8Gj6uTuB1K6UZksc9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:O75347 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-2686341|uniprotkb:B4DT30|ensembl:ENSP00000369736 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:tbca_human(display_long)|uniprotkb:TCP1-chaperonin cofactor A(gene name synonym)|uniprotkb:Tubulin-folding cofactor A(gene name synonym)|uniprotkb:TBCA(gene name)|psi-mi:TBCA(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_004598.1|refseq:NP_001284667.1|ensembl:ENSG00000171530(gene)|ensembl:ENST00000380377(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0007023"(post-chaperonin tubulin folding pathway)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0051087"(chaperone binding)|interpro:IPR004226(Tubulin binding cofactor A)|interpro:IPR036126|mint:O75347|rcsb pdb:1H7C|reactome:R-HSA-389977 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:hETmNl4lTAEyZ89oOKuhkah5vmQ9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P18669 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-717905|uniprotkb:Q9BWC0|ensembl:ENSP00000359991 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:pgam1_human(display_long)|uniprotkb:Phosphoglycerate mutase isozyme B(gene name synonym)|uniprotkb:BPG-dependent PGAM 1(gene name synonym)|uniprotkb:PGAM1(gene name)|psi-mi:PGAM1(display_short)|uniprotkb:CDABP0006(orf name)|uniprotkb:PGAMA(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_002620.1|ensembl:ENSG00000171314(gene)|ensembl:ENST00000334828(transcript)|go:"GO:0004082"(bisphosphoglycerate mutase activity)|go:"GO:0004619"(phosphoglycerate mutase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006096"(glycolytic process)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043456"(regulation of pentose-phosphate shunt)|go:"GO:0045730"(respiratory burst)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001345(Phosphoglycerate/bisphosphoglycerate mutase)|interpro:IPR005952(Phosphoglycerate mutase 1)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR029033|mint:P18669|rcsb pdb:1LJD|rcsb pdb:1YFK|rcsb pdb:1YJX|rcsb pdb:4GPI|rcsb pdb:4GPZ|rcsb pdb:5Y2I|rcsb pdb:5Y2U|rcsb pdb:5Y35|rcsb pdb:5Y64|rcsb pdb:5Y65|rcsb pdb:5ZRM|rcsb pdb:5ZS8|rcsb pdb:6ISN|reactome:R-HSA-6798695|reactome:R-HSA-70171|reactome:R-HSA-70263 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:GI6jwRrX08owCyzx8KnRU8QP2rg9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P40925 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-709625|uniprotkb:B7Z3I7|uniprotkb:Q6I9V0|uniprotkb:B2R5V5|uniprotkb:B4DUN2|uniprotkb:F5H098|ensembl:ENSP00000233114|ensembl:ENSP00000446395 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:mdhc_human(display_long)|uniprotkb:Cytosolic malate dehydrogenase(gene name synonym)|uniprotkb:MDH1(gene name)|psi-mi:MDH1(display_short)|uniprotkb:MDHA(gene name synonym)|uniprotkb:Diiodophenylpyruvate reductase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_001186040.1|refseq:NP_001186041.1|refseq:NP_005908.1|refseq:NP_001303303.1|ensembl:ENSG00000014641(gene)|ensembl:ENST00000233114(transcript)|ensembl:ENST00000544381(transcript)|go:"GO:0004470"(malic enzyme activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0006108"(malate metabolic process)|go:"GO:0006734"(NADH metabolic process)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0030060"(L-malate dehydrogenase activity)|go:"GO:0047860"(diiodophenylpyruvate reductase activity)|go:"GO:0051287"(NAD binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001252(Malate dehydrogenase, active site)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR010945(Malate dehydrogenase, NAD or NADP)|interpro:IPR011274(Malate dehydrogenase, NAD-dependent, cytosolic)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR022383|interpro:IPR036291|mint:P40925|reactome:R-HSA-70263 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:SbY7B81CiCRe8tXpVpSdT1sKGOU9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P60174 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-717475|uniprotkb:D3DUS9|uniprotkb:P00938|uniprotkb:Q6IS07|uniprotkb:Q8WWD0|uniprotkb:Q96AG5|uniprotkb:Q6FHP9|uniprotkb:B7Z5D8|ensembl:ENSP00000379933 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:tpis_human(display_long)|uniprotkb:Triose-phosphate isomerase(gene name synonym)|uniprotkb:TPI1(gene name)|psi-mi:TPI1(display_short)|uniprotkb:TPI(gene name synonym)|uniprotkb:Methylglyoxal synthase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_000356.1|refseq:NP_001152759.1|refseq:NP_001244955.1|ensembl:ENSG00000111669(gene)|ensembl:ENST00000396705(transcript)|go:"GO:0004807"(triose-phosphate isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0008929"(methylglyoxal synthase activity)|go:"GO:0019242"(methylglyoxal biosynthetic process)|go:"GO:0019563"(glycerol catabolic process)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046166"(glyceraldehyde-3-phosphate biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000652(Triosephosphate isomerase)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR020861|interpro:IPR022896|interpro:IPR035990|mint:P60174|rcsb pdb:1HTI|rcsb pdb:1KLG|rcsb pdb:1KLU|rcsb pdb:1WYI|rcsb pdb:2IAM|rcsb pdb:2IAN|rcsb pdb:2JK2|rcsb pdb:2VOM|rcsb pdb:4BR1|rcsb pdb:4E41|rcsb pdb:4POC|rcsb pdb:4POD|rcsb pdb:4UNK|rcsb pdb:4UNL|rcsb pdb:4ZVJ|rcsb pdb:6C2G|rcsb pdb:6D43|rcsb pdb:6NLH|rcsb pdb:6UP1|rcsb pdb:6UP5|rcsb pdb:6UP8|rcsb pdb:6UPF|reactome:R-HSA-70171|reactome:R-HSA-70263 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:FaLt6wGI1Bz2Z81gX35p7sOiMbE9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P58546 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-1051736|ensembl:ENSP00000376800 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:mtpn_human(display_long)|uniprotkb:Protein V-1(gene name synonym)|uniprotkb:MTPN(gene name)|psi-mi:MTPN(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_665807.1|ensembl:ENSG00000105887(gene)|ensembl:ENST00000393085(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006417"(regulation of translation)|go:"GO:0006584"(catecholamine metabolic process)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010557"(positive regulation of macromolecule biosynthetic process)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016202"(regulation of striated muscle tissue development)|go:"GO:0021707"(cerebellar granule cell differentiation)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0051247"(positive regulation of protein metabolic process)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:2000812"(regulation of barbed-end actin filament capping)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|mint:P58546|rcsb pdb:3AAA|rcsb pdb:7DF7|rcsb pdb:7DSA|rcsb pdb:7DSB|dip:DIP-50234N - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:kdJ8vNN4yI2ye49iYUNAtH538b49606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P52565 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-712693|intact:EBI-718039|ensembl:ENSP00000269321|ensembl:ENSP00000441348|ensembl:ENSP00000464205|intact:EBI-2840752|uniprotkb:A8MXW0|uniprotkb:B4DDD3|uniprotkb:B4DUV9|uniprotkb:B2R5X1|uniprotkb:Q6IBM5 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:gdir1_human(display_long)|uniprotkb:Rho-GDI alpha(gene name synonym)|uniprotkb:ARHGDIA(gene name)|psi-mi:ARHGDIA(display_short)|uniprotkb:GDIA1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) ensembl:ENSG00000141522(gene)|ensembl:ENST00000269321(transcript)|ensembl:ENST00000541078(transcript)|ensembl:ENST00000580685(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0005094"(Rho GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005504"(fatty acid binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045202"(synapse)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0071461"(cellular response to redox state)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR000406(RHO protein GDP dissociation inhibitor)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR024792|mint:P52565|rcsb pdb:1CC0|rcsb pdb:1FSO|rcsb pdb:1FST|rcsb pdb:1FT0|rcsb pdb:1FT3|rcsb pdb:1HH4|rcsb pdb:1KMT|rcsb pdb:1QVY|rcsb pdb:1RHO|rcsb pdb:2BXW|rcsb pdb:2JHS|rcsb pdb:2JHT|rcsb pdb:2JHU|rcsb pdb:2JHV|rcsb pdb:2JHW|rcsb pdb:2JHX|rcsb pdb:2JHY|rcsb pdb:2JHZ|rcsb pdb:2JI0|rcsb pdb:2N80|reactome:R-HSA-193634|reactome:R-HSA-209563|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013407|reactome:R-HSA-9013408|go:"GO:0005634"(nucleus)|refseq:NP_001172006.1|refseq:NP_001172007.1|refseq:NP_004300.1|refseq:NP_001288169.1|refseq:NP_001288170.1|refseq:NP_001288171.1|refseq:NP_001288172.1 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:nHmwosTUeo1R72Mp5uHLYdcBofk9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:O14950 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-1642165|uniprotkb:D3DUH6|intact:EBI-2826593|uniprotkb:Q7Z5Z4|uniprotkb:Q13182|ensembl:ENSP00000237500|ensembl:ENSP00000383037|ensembl:ENSP00000463559|ensembl:ENSP00000464464|ensembl:ENSP00000496809 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:ml12b_human(display_long)|uniprotkb:MYL12B(gene name)|psi-mi:MYL12B(display_short)|uniprotkb:MRLC2(gene name synonym)|uniprotkb:Myosin regulatory light chain 2-B, smooth muscle isoform(gene name synonym)|uniprotkb:MLC-2A(gene name synonym)|uniprotkb:SHUJUN-1(gene name synonym)|uniprotkb:MYLC2B(gene name synonym)|uniprotkb:Myosin regulatory light chain MRLC2(gene name synonym)|uniprotkb:Myosin regulatory light chain 20 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_001138416.1|refseq:NP_001138417.1|refseq:NP_291024.1|refseq:NP_001289978.1|ensembl:ENSG00000118680(gene)|ensembl:ENST00000237500(transcript)|ensembl:ENST00000400175(transcript)|ensembl:ENST00000581193(transcript)|ensembl:ENST00000584539(transcript)|ensembl:ENST00000648965(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016460"(myosin II complex)|go:"GO:0030018"(Z disc)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR015070(Region of unknown function DUF1880)|interpro:IPR018247|mint:O14950|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-445355|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:5jOP3J5TW0eU9zwalQ2S4Oist4k9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:Q9Y2B0 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-1054195|uniprotkb:Q9UHE9|uniprotkb:B2R7B9|ensembl:ENSP00000273308 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:cnpy2_human(display_long)|uniprotkb:TMEM4(gene name synonym)|uniprotkb:MIR-interacting saposin-like protein(gene name synonym)|uniprotkb:Transmembrane protein 4(gene name synonym)|uniprotkb:Putative secreted protein Zsig9(gene name synonym)|uniprotkb:CNPY2(gene name)|psi-mi:CNPY2(display_short)|uniprotkb:MSAP(gene name synonym)|uniprotkb:ZSIG9(gene name synonym)|uniprotkb:UNQ1943/PRO4426(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_001177920.1|refseq:NP_055070.1|ensembl:ENSG00000257727(gene)|ensembl:ENST00000273308(transcript)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010988"(regulation of low-density lipoprotein particle clearance)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|interpro:IPR008139(Saposin B)|interpro:IPR021852|interpro:IPR042415|mint:Q9Y2B0|dip:DIP-50705N - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:m8AFLt3+Fjh99ImqcKladnb00jU9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P49006 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-4289961|uniprotkb:Q5TEE6|uniprotkb:Q6NXS5|uniprotkb:D3DPQ0|ensembl:ENSP00000362638 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:mrp_human(display_long)|uniprotkb:MARCKSL1(gene name)|psi-mi:MARCKSL1(display_short)|uniprotkb:MLP(gene name synonym)|uniprotkb:MRP(gene name synonym)|uniprotkb:MARCKS-like protein 1(gene name synonym)|uniprotkb:Macrophage myristoylated alanine-rich C kinase substrate(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) ensembl:ENSG00000175130(gene)|ensembl:ENST00000329421(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0007417"(central nervous system development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002101(Myristoylated alanine-rich C-kinase substrate MARCKS)|mint:P49006|refseq:NP_075385.1 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:nkq8hGJINvCHlZJ3alKkDP+wCxk9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:Q15750 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-358643|uniprotkb:Q2PP09|intact:EBI-3959873|uniprotkb:Q8IZW2|ensembl:ENSP00000216160 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:tab1_human(display_long)|uniprotkb:TAB1(gene name)|psi-mi:TAB1(display_short)|uniprotkb:MAP3K7IP1(gene name synonym)|uniprotkb:TGF-beta-activated kinase 1-binding protein 1(gene name synonym)|uniprotkb:Mitogen-activated protein kinase kinase kinase 7-interacting protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_006107.1|refseq:NP_705717.1|ensembl:ENSP00000216160|ensembl:ENST00000331454|ensembl:ENSP00000333049|go:"GO:0003279"(cardiac septum development)|rcsb pdb:7NTI|go:"GO:0003007"(heart morphogenesis)|ensembl:ENSG00000100324(gene)|ensembl:ENST00000216160(transcript)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0010008"(endosome membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019209"(kinase activator activity)|go:"GO:0030324"(lung development)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035904"(aorta development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0048273"(mitogen-activated protein kinase p38 binding)|go:"GO:0060976"(coronary vasculature development)|interpro:IPR001932(Protein phosphatase 2C-related)|interpro:IPR015655(Protein phosphatase 2C)|interpro:IPR036457|mint:Q15750|rcsb pdb:2J4O|rcsb pdb:2POM|rcsb pdb:2POP|rcsb pdb:2YDS|rcsb pdb:2YIY|rcsb pdb:4AY5|rcsb pdb:4AY6|rcsb pdb:4GS6|rcsb pdb:4KA3|rcsb pdb:4L3P|rcsb pdb:4L52|rcsb pdb:4L53|rcsb pdb:4O91|rcsb pdb:5DIY|rcsb pdb:5E7R|rcsb pdb:5GJD|rcsb pdb:5GJF|rcsb pdb:5GJG|rcsb pdb:5J7S|rcsb pdb:5J8I|rcsb pdb:5J9L|rcsb pdb:5JGA|rcsb pdb:5JGB|rcsb pdb:5JGD|rcsb pdb:5JH6|rcsb pdb:5JK3|rcsb pdb:5NZZ|rcsb pdb:5O90|rcsb pdb:5V5N|rcsb pdb:5VVU|rcsb pdb:7NTH|reactome:R-HSA-168638|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-5357956|reactome:R-HSA-5607764|reactome:R-HSA-5689880|reactome:R-HSA-9014325|reactome:R-HSA-9020702|reactome:R-HSA-937042|reactome:R-HSA-937072|reactome:R-HSA-9645460|reactome:R-HSA-975163|dip:DIP-27524N - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:28+bzs6bpXJTun4XukxC/7oAYSs9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P61916 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-2368946|uniprotkb:Q15668|uniprotkb:Q29413|uniprotkb:B4DQV7|ensembl:ENSP00000451112 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:npc2_human(display_long)|uniprotkb:NPC2(gene name)|psi-mi:NPC2(display_short)|uniprotkb:Niemann-Pick disease type C2 protein(gene name synonym)|uniprotkb:HE1(gene name synonym)|uniprotkb:Human epididymis-specific protein 1(gene name synonym)|uniprotkb:Epididymal secretory protein E1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_006423.1|ensembl:ENSG00000119655(gene)|ensembl:ENST00000555619(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0015485"(cholesterol binding)|go:"GO:0015914"(phospholipid transport)|go:"GO:0015918"(sterol transport)|go:"GO:0019747"(regulation of isoprenoid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030301"(cholesterol transport)|go:"GO:0032366"(intracellular sterol transport)|go:"GO:0032367"(intracellular cholesterol transport)|go:"GO:0032934"(sterol binding)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0046836"(glycolipid transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR003172(MD-2-related lipid-recognition)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR033916|interpro:IPR039670|mint:P61916|rcsb pdb:5KWY|rcsb pdb:6W5V|reactome:R-HSA-6798695|reactome:R-HSA-8964038 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:v1WSWKL+SaMlpcVh7Qhespo84Lg9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P29401 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-1050560|uniprotkb:Q8TBA3|uniprotkb:Q96HH3|uniprotkb:A8K089|uniprotkb:B4DE31|uniprotkb:E7EPA7|ensembl:ENSP00000405455|ensembl:ENSP00000417773|intact:EBI-11110174 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:tkt_human(display_long)|uniprotkb:TKT(gene name)|psi-mi:TKT(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_001055.1|refseq:NP_001128527.1|refseq:NP_001244957.1|ensembl:ENSG00000163931(gene)|ensembl:ENST00000423525(transcript)|ensembl:ENST00000462138(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004802"(transketolase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005777"(peroxisome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006098"(pentose-phosphate shunt)|go:"GO:0009052"(pentose-phosphate shunt, non-oxidative branch)|go:"GO:0016604"(nuclear body)|go:"GO:0030976"(thiamine pyrophosphate binding)|go:"GO:0031982"(vesicle)|go:"GO:0040008"(regulation of growth)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046166"(glyceraldehyde-3-phosphate biosynthetic process)|go:"GO:0046390"(ribose phosphate biosynthetic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR005474(Transketolase, N-terminal)|interpro:IPR005475(Transketolase, central region)|interpro:IPR009014(Transketolase, C-terminal/Pyruvate-ferredoxin oxidoreductase, domain II)|interpro:IPR020826|interpro:IPR029061|interpro:IPR033248|mint:P29401|rcsb pdb:3MOS|rcsb pdb:3OOY|rcsb pdb:4KXU|rcsb pdb:4KXV|rcsb pdb:4KXW|rcsb pdb:4KXX|rcsb pdb:4KXY|rcsb pdb:6HA3|rcsb pdb:6HAD|rcsb pdb:6RJB|reactome:R-HSA-163754|reactome:R-HSA-71336|refseq:XP_011532356.1 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:Z3Ad5GdEd0rFCT9uHv85N+2KAAY9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P07737 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-713780|ensembl:ENSP00000225655|uniprotkb:Q53Y44 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:prof1_human(display_long)|uniprotkb:Profilin I(gene name synonym)|uniprotkb:PFN1(gene name)|psi-mi:PFN1(display_short)|uniprotkb:Epididymis tissue protein Li 184a(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) ensembl:ENSG00000108518(gene)|ensembl:ENST00000225655(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0060074"(synapse maturation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0072562"(blood microparticle)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900029"(positive regulation of ruffle assembly)|interpro:IPR005454(Profilin, Mammalian)|interpro:IPR005455(Profilin, plant)|interpro:IPR027310|interpro:IPR029892|interpro:IPR036140|mint:P07737|rcsb pdb:1AWI|rcsb pdb:1CF0|rcsb pdb:1CJF|rcsb pdb:1FIK|rcsb pdb:1FIL|rcsb pdb:1PFL|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:3CHW|rcsb pdb:4X1L|rcsb pdb:4X1M|rcsb pdb:4X25|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6NBW|reactome:R-HSA-114608|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|reactome:R-HSA-4086400|reactome:R-HSA-5663220|reactome:R-HSA-376176|refseq:NP_005013.1|dip:DIP-30N - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:CncaC5RMylvzFLhqzpS+VbhQn6I9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P00558 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-709599|uniprotkb:A8K4W6|uniprotkb:Q5J7W1|uniprotkb:Q6IBT6|uniprotkb:Q8NI87|uniprotkb:B7Z7A9|ensembl:ENSP00000362413 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:pgk1_human(display_long)|uniprotkb:Primer recognition protein 2(gene name synonym)|uniprotkb:Cell migration-inducing gene 10 protein(gene name synonym)|uniprotkb:PGK1(gene name)|psi-mi:PGK1(display_short)|uniprotkb:PGKA(gene name synonym)|uniprotkb:OK/SW-cl.110(orf name)|uniprotkb:MIG10(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_000282.1|dip:DIP-33679N|ensembl:ENSG00000102144(gene)|ensembl:ENST00000373316(transcript)|go:"GO:0004618"(phosphoglycerate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0006094"(gluconeogenesis)|go:"GO:0006096"(glycolytic process)|go:"GO:0016020"(membrane)|go:"GO:0016310"(phosphorylation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031639"(plasminogen activation)|go:"GO:0043531"(ADP binding)|go:"GO:0045121"(membrane raft)|go:"GO:0047134"("protein-disulfide reductase (NAD(P)) activity")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071456"(cellular response to hypoxia)|interpro:IPR001576(Phosphoglycerate kinase)|interpro:IPR015824(Phosphoglycerate kinase, N-terminal)|interpro:IPR015911(Phosphoglycerate kinase, conserved site)|interpro:IPR036043|mint:P00558|rcsb pdb:2WZB|rcsb pdb:2WZC|rcsb pdb:2WZD|rcsb pdb:2X13|rcsb pdb:2X14|rcsb pdb:2X15|rcsb pdb:2XE6|rcsb pdb:2XE7|rcsb pdb:2XE8|rcsb pdb:2Y3I|rcsb pdb:2YBE|rcsb pdb:2ZGV|rcsb pdb:3C39|rcsb pdb:3C3A|rcsb pdb:3C3B|rcsb pdb:3C3C|rcsb pdb:3ZOZ|rcsb pdb:4AXX|rcsb pdb:4O33|rcsb pdb:5M1R|rcsb pdb:5M3U|rcsb pdb:5M6Z|rcsb pdb:5MXM|rcsb pdb:5NP8|rcsb pdb:5O7D|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:fkyBDnIx/ii6vfJjWJsxWi0piOQ9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:Q9BYE3 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-6658837|ensembl:ENSP00000357776|uniprotkb:Q3MIL1 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:lce3d_human(display_long)|uniprotkb:LCE3D(gene name)|psi-mi:LCE3D(display_short)|uniprotkb:LEP16(gene name synonym)|uniprotkb:Late envelope protein 16(gene name synonym)|uniprotkb:SPRL6A(gene name synonym)|uniprotkb:SPRL6B(gene name synonym)|uniprotkb:Small proline-rich-like epidermal differentiation complex protein 6A(gene name synonym)|uniprotkb:Small proline-rich-like epidermal differentiation complex protein 6B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) reactome:R-HSA-6809371|ensembl:ENSG00000163202(gene)|ensembl:ENST00000368787(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0031424"(keratinization)|interpro:IPR028205|mint:Q9BYE3|refseq:NP_115952.1 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:Z4ioMrxzMFukbltcko4qJkIVsXw9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P05455 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-358037|ensembl:ENSP00000260956|ensembl:ENSP00000386636|uniprotkb:Q15367|uniprotkb:Q53XJ4 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:la_human(display_long)|uniprotkb:SSB(gene name)|psi-mi:SSB(display_short)|uniprotkb:Sjoegren syndrome type B antigen(gene name synonym)|uniprotkb:La ribonucleoprotein(gene name synonym)|uniprotkb:La autoantigen(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_003133.1|ensembl:ENSG00000138385(gene)|ensembl:ENST00000260956(transcript)|ensembl:ENST00000409333(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006400"(tRNA modification)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0008033"(tRNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008334"(histone mRNA metabolic process)|go:"GO:0042780"(tRNA 3'-end processing)|go:"GO:0071045"(nuclear histone mRNA catabolic process)|refseq:NP_001281074.1|dip:DIP-29750N|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002344(Lupus La protein)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR014886(RNA binding motif)|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|mint:P05455|rcsb pdb:1OWX|rcsb pdb:1S79|rcsb pdb:1S7A|rcsb pdb:1YTY|rcsb pdb:1ZH5|rcsb pdb:2VOD|rcsb pdb:2VON|rcsb pdb:2VOO|rcsb pdb:2VOP|reactome:R-HSA-73980|reactome:R-HSA-749476 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:Lgpr3jgLWGk3AZzPwjB1swJRsoQ9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P80723 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-358583|uniprotkb:D3DTD5|uniprotkb:O43596|uniprotkb:Q5U0S0|uniprotkb:Q9BWA5|uniprotkb:B4DJA8|ensembl:ENSP00000319281|ensembl:ENSP00000482066 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:basp1_human(display_long)|uniprotkb:BASP1(gene name)|psi-mi:BASP1(display_short)|uniprotkb:NAP22(gene name synonym)|uniprotkb:Neuronal axonal membrane protein NAP-22(gene name synonym)|uniprotkb:22 kDa neuronal tissue-enriched acidic protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_006308.3|refseq:NP_001258535.1|ensembl:ENSG00000176788(gene)|ensembl:ENST00000322611(transcript)|ensembl:ENST00000616743(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007356"(thorax and anterior abdomen determination)|go:"GO:0008406"(gonad development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030054"(cell junction)|go:"GO:0030426"(growth cone)|go:"GO:0031982"(vesicle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0060231"(mesenchymal to epithelial transition)|go:"GO:0060421"(positive regulation of heart growth)|go:"GO:0060539"(diaphragm development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072075"(metanephric mesenchyme development)|go:"GO:0072112"(glomerular visceral epithelial cell differentiation)|go:"GO:2001076"(positive regulation of metanephric ureteric bud development)|interpro:IPR008408(Brain acid soluble protein 1)|mint:P80723|reactome:R-HSA-9035034 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:X+L20HKimV3J+vLnQljg+x78+e09606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P16949 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-445909|uniprotkb:A2A2D1|uniprotkb:B7Z8N4|uniprotkb:D3DPJ5|uniprotkb:B2R4E7|ensembl:ENSP00000350531|ensembl:ENSP00000363409|ensembl:ENSP00000382633|ensembl:ENSP00000387858 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:stmn1_human(display_long)|uniprotkb:Phosphoprotein p19(gene name synonym)|uniprotkb:Leukemia-associated phosphoprotein p18(gene name synonym)|uniprotkb:Oncoprotein 18(gene name synonym)|uniprotkb:pp17(gene name synonym)|uniprotkb:Prosolin(gene name synonym)|uniprotkb:Metablastin(gene name synonym)|uniprotkb:Protein Pr22(gene name synonym)|uniprotkb:STMN1(gene name)|psi-mi:STMN1(display_short)|uniprotkb:LAP18(gene name synonym)|uniprotkb:OP18(gene name synonym)|uniprotkb:C1orf215(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_001138926.1|refseq:NP_005554.1|refseq:NP_981944.1|refseq:NP_981946.1|ensembl:ENST00000357865(transcript)|ensembl:ENST00000374291(transcript)|ensembl:ENST00000399728(transcript)|ensembl:ENST00000455785(transcript)|go:"GO:0000281"(mitotic cytokinesis)|ensembl:ENSG00000117632(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0009615"(response to virus)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:0031115"(negative regulation of microtubule polymerization)|go:"GO:0031175"(neuron projection development)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043005"(neuron projection)|go:"GO:0048012"(hepatocyte growth factor receptor signaling pathway)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070495"(negative regulation of thrombin-activated receptor signaling pathway)|go:"GO:1905098"(negative regulation of guanyl-nucleotide exchange factor activity)|mint:P16949|interpro:IPR000956(Stathmin)|interpro:IPR030514|interpro:IPR036002|reactome:R-HSA-1251985 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:gew+NqUuLLolCLCXOyXIZkRieIs9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P99999 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-446479|uniprotkb:A4D166|uniprotkb:P00001|uniprotkb:Q6NUR2|uniprotkb:Q6NX69|uniprotkb:Q96BV4|uniprotkb:B2R4I1|ensembl:ENSP00000307786|ensembl:ENSP00000386270|ensembl:ENSP00000387279 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:cyc_human(display_long)|uniprotkb:CYCS(gene name)|psi-mi:CYCS(display_short)|uniprotkb:CYC(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_061820.1|dip:DIP-29683N|ensembl:ENSG00000172115(gene)|ensembl:ENST00000305786(transcript)|ensembl:ENST00000409409(transcript)|ensembl:ENST00000409764(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005829"(cytosol)|go:"GO:0006122"(mitochondrial electron transport, ubiquinol to cytochrome c)|go:"GO:0006123"(mitochondrial electron transport, cytochrome c to oxygen)|go:"GO:0006915"(apoptotic process)|go:"GO:0008635"(activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c)|go:"GO:0009055"(electron transfer activity)|go:"GO:0020037"(heme binding)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0045333"(cellular respiration)|go:"GO:0046872"(metal ion binding)|go:"GO:0070469"(respirasome)|interpro:IPR002327(Cytochrome c, class IA/ IB)|interpro:IPR009056(Cytochrome c, monohaem)|interpro:IPR036909|mint:P99999|rcsb pdb:1J3S|rcsb pdb:2N3Y|rcsb pdb:2N9I|rcsb pdb:2N9J|rcsb pdb:3NWV|rcsb pdb:3ZCF|rcsb pdb:3ZOO|rcsb pdb:5EXQ|rcsb pdb:5O10|rcsb pdb:5TY3|rcsb pdb:6DUJ|rcsb pdb:6ECJ|reactome:R-HSA-111457|reactome:R-HSA-111458|reactome:R-HSA-111459|reactome:R-HSA-111463|reactome:R-HSA-111464|reactome:R-HSA-2151201|reactome:R-HSA-3299685|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-611105|reactome:R-HSA-9627069|reactome:R-HSA-9707564 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:vSMR7doWXd3VBP8jmhl6cUjccdY9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P06753 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-355607|uniprotkb:P12324|uniprotkb:Q969Q2|uniprotkb:Q9NQH8|uniprotkb:Q5VU71|uniprotkb:Q2QD06|uniprotkb:D3DV71|ensembl:ENSP00000498577|intact:EBI-11063811|uniprotkb:Q5VU66|uniprotkb:Q5VU72|intact:EBI-4289841|uniprotkb:Q5VU58|uniprotkb:Q5VU63|uniprotkb:Q8TCG3 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:tpm3_human(display_long)|uniprotkb:TPM3(gene name)|psi-mi:TPM3(display_short)|uniprotkb:Tropomyosin-3(gene name synonym)|uniprotkb:Gamma-tropomyosin(gene name synonym)|uniprotkb:Tropomyosin-5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_001265120.1|refseq:NP_001036816.1|refseq:NP_001036817.1|refseq:NP_689476.2|refseq:NP_705935.1|ensembl:ENSG00000143549(gene)|ensembl:ENST00000651641(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005862"(muscle thin filament tropomyosin)|go:"GO:0005884"(actin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000533(Tropomyosin)|mint:P06753|rcsb pdb:6OTN|reactome:R-HSA-390522|reactome:R-HSA-445355|reactome:R-HSA-9013424|refseq:NP_001036818.1|refseq:NP_001265118.1 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:vHELhEyfZxpK8zHMEveODiYBZmM9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:Q9NQG5 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-747925|uniprotkb:Q1WDE7|uniprotkb:Q6PKF4|ensembl:ENSP00000362532 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:rpr1b_human(display_long)|uniprotkb:RPRD1B(gene name)|psi-mi:RPRD1B(display_short)|uniprotkb:C20orf77(gene name synonym)|uniprotkb:CREPT(gene name synonym)|uniprotkb:Cell cycle-related and expression-elevated protein in tumor(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_067038.1|ensembl:ENSG00000101413(gene)|ensembl:ENST00000373433(transcript)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0031124"(mRNA 3'-end processing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0070940"(dephosphorylation of RNA polymerase II C-terminal domain)|interpro:IPR006569(Regulation of nuclear pre-mRNA protein)|interpro:IPR008942(ENTH/VHS)|interpro:IPR032337|mint:Q9NQG5|rcsb pdb:4FLA|rcsb pdb:4FU3|rcsb pdb:4HFG|rcsb pdb:4NAD|rcsb pdb:4Q94|rcsb pdb:4Q96|reactome:R-HSA-6807505|dip:DIP-61537N - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:1P0sOiLV5eQXrRj+vENpc6L/z/Q9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:A6NHG4 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-25486103|ensembl:ENSP00000215770|ensembl:ENSP00000479063|uniprotkb:B4DJJ7 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:ddtl_human(display_long)|uniprotkb:DDTL(gene name)|psi-mi:DDTL(display_short)|uniprotkb:D-dopachrome tautomerase-like protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) ensembl:ENSG00000099974(gene)|ensembl:ENSG00000275758(gene)|ensembl:ENST00000215770(transcript)|ensembl:ENST00000621454(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016829"(lyase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001398(Macrophage migration inhibitory factor)|interpro:IPR014347(Tautomerase)|interpro:IPR019829|mint:A6NHG4|refseq:NP_001077862.1 - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:BbLBIp2oD+vVNPVoe4AzbqoxF009606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P14174 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-372712|uniprotkb:A5Z1R8|uniprotkb:B2R4S3|uniprotkb:Q6FHV0|uniprotkb:Q2V4Y5|ensembl:ENSP00000215754|ensembl:ENSP00000482779 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:mif_human(display_long)|uniprotkb:MIF(gene name)|psi-mi:MIF(display_short)|uniprotkb:MMIF(gene name synonym)|uniprotkb:GLIF(gene name synonym)|uniprotkb:Phenylpyruvate tautomerase(gene name synonym)|uniprotkb:Glycosylation-inhibiting factor(gene name synonym)|uniprotkb:L-dopachrome tautomerase(gene name synonym)|uniprotkb:L-dopachrome isomerase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_002406.1|ensembl:ENST00000215754(transcript)|ensembl:ENST00000613839(transcript)|go:"GO:0001516"(prostaglandin biosynthetic process)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0004167"(dopachrome isomerase activity)|go:"GO:0005125"(cytokine activity)|go:"GO:0005126"(cytokine receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|ensembl:ENSG00000276701(gene)|go:"GO:0006954"(inflammatory response)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010739"(positive regulation of protein kinase A signaling)|go:"GO:0010760"(negative regulation of macrophage chemotaxis)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030890"(positive regulation of B cell proliferation)|go:"GO:0031982"(vesicle)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042056"(chemoattractant activity)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043030"(regulation of macrophage activation)|go:"GO:0043066"(negative regulation of apoptotic process)|ensembl:ENSG00000240972(gene)|go:"GO:0043518"(negative regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0045087"(innate immune response)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0050178"(phenylpyruvate tautomerase activity)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0090344"(negative regulation of cell aging)|go:"GO:1902166"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001398(Macrophage migration inhibitory factor)|interpro:IPR014347(Tautomerase)|interpro:IPR019829|mint:P14174|rcsb pdb:1CGQ|rcsb pdb:1GCZ|rcsb pdb:1GD0|rcsb pdb:1GIF|rcsb pdb:1LJT|rcsb pdb:1MIF|rcsb pdb:1P1G|rcsb pdb:2OOH|rcsb pdb:2OOW|rcsb pdb:2OOZ|rcsb pdb:3B9S|rcsb pdb:3CE4|rcsb pdb:3DJH|rcsb pdb:3DJI|rcsb pdb:3HOF|rcsb pdb:3IJG|rcsb pdb:3IJJ|rcsb pdb:3JSF|rcsb pdb:3JSG|rcsb pdb:3JTU|rcsb pdb:3L5P|rcsb pdb:3L5R|rcsb pdb:3L5S|rcsb pdb:3L5T|rcsb pdb:3L5U|rcsb pdb:3L5V|rcsb pdb:3SMB|rcsb pdb:3SMC|rcsb pdb:3U18|rcsb pdb:3WNR|rcsb pdb:3WNS|rcsb pdb:3WNT|rcsb pdb:4ETG|rcsb pdb:4EUI|rcsb pdb:4EVG|rcsb pdb:4F2K|rcsb pdb:4GRN|rcsb pdb:4GRO|rcsb pdb:4GRP|rcsb pdb:4GRQ|rcsb pdb:4GRR|rcsb pdb:4GRU|rcsb pdb:4GUM|rcsb pdb:4K9G|rcsb pdb:4OSF|rcsb pdb:4OYQ|rcsb pdb:4P01|rcsb pdb:4P0H|rcsb pdb:4PKK|rcsb pdb:4PKZ|rcsb pdb:4PLU|rcsb pdb:4TRF|rcsb pdb:4TRU|rcsb pdb:4WR8|rcsb pdb:4WRB|rcsb pdb:4XX7|rcsb pdb:4XX8|rcsb pdb:4Z15|rcsb pdb:4Z1T|rcsb pdb:4Z1U|rcsb pdb:5B4O|rcsb pdb:5BS9|rcsb pdb:5BSC|rcsb pdb:5BSI|rcsb pdb:5BSJ|rcsb pdb:5EIZ|rcsb pdb:5HVS|rcsb pdb:5HVT|rcsb pdb:5HVV|rcsb pdb:5J7P|rcsb pdb:5J7Q|rcsb pdb:5UMJ|rcsb pdb:5UMK|rcsb pdb:5UZY|rcsb pdb:5V70|rcsb pdb:5V73|rcsb pdb:5XEJ|rcsb pdb:1CA7|rcsb pdb:6B1C|rcsb pdb:6B1K|rcsb pdb:6B2C|rcsb pdb:6BG6|rcsb pdb:6BG7|rcsb pdb:6CB5|rcsb pdb:6CBF|rcsb pdb:6CBG|rcsb pdb:6FVE|rcsb pdb:6FVH|rcsb pdb:6OY8|rcsb pdb:6OYB|rcsb pdb:6OYE|rcsb pdb:6OYG|rcsb pdb:6PEG|reactome:R-HSA-202733|reactome:R-HSA-6798695|reactome:R-HSA-8950505|rcsb pdb:6CBH|dip:DIP-31137N - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:Vk+Sfaz5c59y8dKKJ4Qn+7fjwvQ9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:Q70IA6 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-2558739|uniprotkb:Q96M67|uniprotkb:B4DKP3 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:mob2_human(display_long)|uniprotkb:MOB2(gene name)|psi-mi:MOB2(display_short)|uniprotkb:HCCA2(gene name synonym)|uniprotkb:Mob2 homolog(gene name synonym)|uniprotkb:Mps one binder kinase activator-like 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_001165694.1|refseq:NP_443731.2|interpro:IPR005301(Mob1/phocein)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR036703|mint:Q70IA6 - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:bPhfXMdT6x7s05Ufn4VZrMRgcL89606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P04075 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-709613|uniprotkb:Q6FH76|uniprotkb:Q96B15|uniprotkb:Q9BWD9|uniprotkb:B4DXI7|uniprotkb:Q6FI10|uniprotkb:Q9UCN2|ensembl:ENSP00000400452|ensembl:ENSP00000455700|ensembl:ENSP00000455800|ensembl:ENSP00000494188 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:aldoa_human(display_long)|uniprotkb:Muscle-type aldolase(gene name synonym)|uniprotkb:Lung cancer antigen NY-LU-1(gene name synonym)|uniprotkb:ALDOA(gene name)|psi-mi:ALDOA(display_short)|uniprotkb:ALDA(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_000025.1|refseq:NP_001121089.1|refseq:NP_001230106.1|refseq:NP_908930.1|refseq:NP_908932.1|refseq:XP_011544070.1|ensembl:ENSG00000149925(gene)|ensembl:ENST00000412304(transcript)|ensembl:ENST00000563060(transcript)|ensembl:ENST00000569545(transcript)|ensembl:ENST00000643777(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0061827"(sperm head)|go:"GO:0070061"(fructose binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR029768|mint:P04075|rcsb pdb:1ALD|rcsb pdb:2ALD|rcsb pdb:4ALD|rcsb pdb:5KY6|reactome:R-HSA-114608|reactome:R-HSA-6798695|reactome:R-HSA-70171|reactome:R-HSA-70263 - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:/UgTtKPQj2ZyKznKIfE9OVUcDFI9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P04080 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-1051966|ensembl:ENSP00000291568 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:cytb_human(display_long)|uniprotkb:Stefin-B(gene name synonym)|uniprotkb:Liver thiol proteinase inhibitor(gene name synonym)|uniprotkb:CPI-B(gene name synonym)|uniprotkb:CSTB(gene name)|psi-mi:CSTB(display_short)|uniprotkb:CST6(gene name synonym)|uniprotkb:STFB(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_000091.1|ensembl:ENSG00000160213(gene)|ensembl:ENST00000291568(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0010466"(negative regulation of peptidase activity)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|interpro:IPR001713(Proteinase inhibitor I25A, stefin A)|interpro:IPR018073|mint:P04080|rcsb pdb:1STF|rcsb pdb:2OCT|rcsb pdb:4N6V|reactome:R-HSA-6798695 - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:KwR0XgOq6SeHdqxriNE8xIUMmUo9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P61604 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-711483|uniprotkb:O95421|uniprotkb:Q04984|uniprotkb:Q53X54|ensembl:ENSP00000233893|uniprotkb:Q9UDH0 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:ch10_human(display_long)|uniprotkb:HSPE1(gene name)|psi-mi:HSPE1(display_short)|uniprotkb:10 kDa chaperonin(gene name synonym)|uniprotkb:Chaperonin 10(gene name synonym)|uniprotkb:Early-pregnancy factor(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) interpro:IPR020818|interpro:IPR037124|mint:P61604|rcsb pdb:4PJ1|rcsb pdb:6HT7|rcsb pdb:6MRC|rcsb pdb:6MRD|reactome:R-HSA-9013408|ensembl:ENSG00000115541(gene)|ensembl:ENST00000233893(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006457"(protein folding)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0016020"(membrane)|go:"GO:0046872"(metal ion binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR011032(GroES-like)|interpro:IPR018369|refseq:NP_002148.1 - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:BmnGoMnA2QIr3Dr0fElMtTgRztA9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P30101 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-979862|uniprotkb:Q13453|uniprotkb:Q14255|uniprotkb:Q8IYF8|uniprotkb:Q9UMU7|ensembl:ENSP00000300289 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:pdia3_human(display_long)|uniprotkb:Disulfide isomerase ER-60(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 60(gene name synonym)|uniprotkb:58 kDa microsomal protein(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 57(gene name synonym)|uniprotkb:58 kDa glucose-regulated protein(gene name synonym)|uniprotkb:PDIA3(gene name)|psi-mi:PDIA3(display_short)|uniprotkb:ERP60(gene name synonym)|uniprotkb:GRP58(gene name synonym)|uniprotkb:ERP57(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) interpro:IPR036249|interpro:IPR041868|mint:P30101|rcsb pdb:2ALB|rcsb pdb:2DMM|rcsb pdb:2H8L|rcsb pdb:3F8U|rcsb pdb:6ENY|reactome:R-HSA-1236974|reactome:R-HSA-901042|reactome:R-HSA-983170|interpro:IPR017937|ensembl:ENSG00000167004(gene)|ensembl:ENST00000300289(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004629"(phospholipase C activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005925"(focal adhesion)|go:"GO:0006457"(protein folding)|go:"GO:0009986"(cell surface)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015036"(disulfide oxidoreductase activity)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|refseq:NP_005304.3|dip:DIP-29132N - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:N/XktiLWB/cPju9nCq6yeyXnO1Q9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P62857 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-353027|ensembl:ENSP00000472469|uniprotkb:P25112 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:rs28_human(display_long)|uniprotkb:RPS28(gene name)|psi-mi:RPS28(display_short)|uniprotkb:Small ribosomal subunit protein eS28(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) mint:P62857|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|ensembl:ENSG00000233927(gene)|ensembl:ENST00000600659(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0042254"(ribosome biogenesis)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098556"(cytoplasmic side of rough endoplasmic reticulum membrane)|interpro:IPR000289(Ribosomal protein S28e)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR028626|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZM7|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001022.1 - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:G4t8mOlzIiHEOXu+uS+AfySWAnM9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P06454 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-2682091|uniprotkb:Q15249|uniprotkb:Q15592|ensembl:ENSP00000344547 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:ptma_human(display_long)|uniprotkb:TMSA(gene name synonym)|uniprotkb:PTMA(gene name)|psi-mi:PTMA(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_001092755.1|refseq:NP_002814.3|ensembl:ENSG00000187514(gene)|ensembl:ENST00000341369(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR004931(Prothymosin/parathymosin)|mint:P06454|rcsb pdb:2L9I|rcsb pdb:2MNQ|dip:DIP-40743N - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:scRCSTJyl5e12uNhBR+L4CKQ6Ac9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:Q9UHL4 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-372284|uniprotkb:Q969X4|uniprotkb:Q5VSF1|uniprotkb:A8K7U7|ensembl:ENSP00000360635 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:dpp2_human(display_long)|uniprotkb:DPP7(gene name)|psi-mi:DPP7(display_short)|uniprotkb:DPP2(gene name synonym)|uniprotkb:QPP(gene name synonym)|uniprotkb:Dipeptidyl peptidase II(gene name synonym)|uniprotkb:Dipeptidyl aminopeptidase II(gene name synonym)|uniprotkb:Quiescent cell proline dipeptidase(gene name synonym)|uniprotkb:Dipeptidyl peptidase 7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) ensembl:ENSG00000176978(gene)|ensembl:ENST00000371579(transcript)|go:"GO:0004177"(aminopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006508"(proteolysis)|go:"GO:0008236"(serine-type peptidase activity)|go:"GO:0008239"(dipeptidyl-peptidase activity)|go:"GO:0031982"(vesicle)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR008758(Peptidase S28)|interpro:IPR029058|interpro:IPR042269|rcsb pdb:3JYH|rcsb pdb:3N0T|rcsb pdb:4EBB|reactome:R-HSA-6798695|mint:Q9UHL4|refseq:NP_037511.2 - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:MdRmqG846ZvKRuJHrPJ6of20pOU9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P13667 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-1054653|uniprotkb:A8K4K6|uniprotkb:Q549T6|ensembl:ENSP00000499129 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:pdia4_human(display_long)|uniprotkb:Endoplasmic reticulum resident protein 72(gene name synonym)|uniprotkb:PDIA4(gene name)|psi-mi:PDIA4(display_short)|uniprotkb:ERP70(gene name synonym)|uniprotkb:ERP72(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 70(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_004902.1|ensembl:ENSG00000155660(gene)|ensembl:ENST00000652332(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003756"(protein disulfide isomerase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0006457"(protein folding)|go:"GO:0009306"(protein secretion)|go:"GO:0009986"(cell surface)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0042470"(melanosome)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR005788(Disulphide isomerase)|interpro:IPR005792(Protein disulphide isomerase)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR017068(Protein disulphide-isomerase A4)|interpro:IPR017937|interpro:IPR036249|interpro:IPR041866|mint:P13667|rcsb pdb:3IDV - - comment:"author score: 29" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:m9nI8RSOEnIsBjDnQa4fbkT+v2Y9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P27797 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-1049597|uniprotkb:Q6IAT4|uniprotkb:Q9UDG2|ensembl:ENSP00000320866|ensembl:ENSP00000466037 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:calr_human(display_long)|uniprotkb:CRP55(gene name synonym)|uniprotkb:Calregulin(gene name synonym)|uniprotkb:HACBP(gene name synonym)|uniprotkb:Endoplasmic reticulum resident protein 60(gene name synonym)|uniprotkb:grp60(gene name synonym)|uniprotkb:CALR(gene name)|psi-mi:CALR(display_short)|uniprotkb:CRTC(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_004334.1|ensembl:ENSG00000179218(gene)|ensembl:ENST00000316448(transcript)|ensembl:ENST00000586967(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001849"(complement component C1q complex binding)|go:"GO:0002502"(peptide antigen assembly with MHC class I protein complex)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005506"(iron ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022417"(protein maturation by protein folding)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0033018"(sarcoplasmic reticulum lumen)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0033144"(negative regulation of intracellular steroid hormone receptor signaling pathway)|go:"GO:0033574"(response to testosterone)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0040020"(regulation of meiotic nuclear division)|go:"GO:0042277"(peptide binding)|go:"GO:0042493"|go:"GO:0042562"(hormone binding)|go:"GO:0042824"(MHC class I peptide loading complex)|go:"GO:0042921"(glucocorticoid receptor signaling pathway)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044322"(endoplasmic reticulum quality control compartment)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048387"(negative regulation of retinoic acid receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051208"(sequestering of calcium ion)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060473"(cortical granule)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071556"(integral component of lumenal side of endoplasmic reticulum membrane)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0090398"(cellular senescence)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901164"(negative regulation of trophoblast cell migration)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:2000510"(positive regulation of dendritic cell chemotaxis)|interpro:IPR001580(Calreticulin/calnexin)|interpro:IPR009033(Calreticulin/calnexin, P)|interpro:IPR009169(Calreticulin)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR018124|mint:P27797|rcsb pdb:2CLR|rcsb pdb:3DOW|rcsb pdb:3POS|rcsb pdb:3POW|rcsb pdb:5LK5|rcsb pdb:5V90|rcsb pdb:6ENY|reactome:R-HSA-1236974|reactome:R-HSA-168316|reactome:R-HSA-3000480|reactome:R-HSA-3000484|reactome:R-HSA-381183|reactome:R-HSA-901042|reactome:R-HSA-983170|dip:DIP-104N - - comment:"author score: 30" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:FSPSiiN6YTaETDyAWwAP3wV6zRI9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P29966 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-1047781|uniprotkb:E1P560|uniprotkb:Q2LA83|uniprotkb:Q5TDB7|ensembl:ENSP00000478061 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:marcs_human(display_long)|uniprotkb:Protein kinase C substrate, 80 kDa protein, light chain(gene name synonym)|uniprotkb:MARCKS(gene name)|psi-mi:MARCKS(display_short)|uniprotkb:MACS(gene name synonym)|uniprotkb:PRKCSL(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_002347.5|ensembl:ENSG00000277443(gene)|ensembl:ENST00000612661(transcript)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007417"(central nervous system development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032432"(actin filament bundle)|go:"GO:0042585"(germinal vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002101(Myristoylated alanine-rich C-kinase substrate MARCKS)|mint:P29966|reactome:R-HSA-399997 - - comment:"author score: 30" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:28v6sOqwULr0AvfJr7yAal9Yh1g9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P00441 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-990792|uniprotkb:A6NHJ0|uniprotkb:Q16669|uniprotkb:Q16711|uniprotkb:Q16838|uniprotkb:Q16839|uniprotkb:Q16840|uniprotkb:Q6NR85|ensembl:ENSP00000270142|uniprotkb:D3DSE4 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:sodc_human(display_long)|uniprotkb:Superoxide dismutase 1(gene name synonym)|uniprotkb:SOD1(gene name)|psi-mi:SOD1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) ensembl:ENSG00000142168(gene)|ensembl:ENST00000270142(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0000303"(response to superoxide)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001890"(placenta development)|go:"GO:0001895"(retina homeostasis)|go:"GO:0002262"(myeloid cell homeostasis)|go:"GO:0004784"(superoxide dismutase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005764"(lysosome)|go:"GO:0005777"(peroxisome)|go:"GO:0005829"(cytosol)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007566"(embryo implantation)|go:"GO:0007569"(cell aging)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008089"(anterograde axonal transport)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0001975"(response to amphetamine)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0032930"(positive regulation of superoxide anion generation)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033081"(regulation of T cell differentiation in thymus)|go:"GO:0034465"(response to carbon monoxide)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0040014"(regulation of multicellular organism growth)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042554"(superoxide anion generation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045471"(response to ethanol)|go:"GO:0045541"(negative regulation of cholesterol biosynthetic process)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0046620"(regulation of organ growth)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009408"(response to heat)|go:"GO:0010033"(response to organic substance)|go:"GO:0019226"(transmission of nerve impulse)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0031045"(dense core granule)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031667"(response to nutrient levels)|interpro:IPR024134|interpro:IPR036423|mint:P00441|rcsb pdb:1AZV|rcsb pdb:1BA9|rcsb pdb:1DSW|rcsb pdb:1FUN|rcsb pdb:1HL4|rcsb pdb:1HL5|rcsb pdb:1KMG|rcsb pdb:1L3N|rcsb pdb:1MFM|rcsb pdb:1N18|rcsb pdb:1N19|interpro:IPR018152|rcsb pdb:1OEZ|rcsb pdb:1OZT|rcsb pdb:1OZU|rcsb pdb:1P1V|rcsb pdb:1PTZ|rcsb pdb:1PU0|rcsb pdb:1RK7|rcsb pdb:1SOS|rcsb pdb:1SPD|rcsb pdb:1UXL|rcsb pdb:1UXM|rcsb pdb:2AF2|rcsb pdb:2C9S|rcsb pdb:2C9U|rcsb pdb:2C9V|rcsb pdb:2GBT|rcsb pdb:2GBU|rcsb pdb:2GBV|rcsb pdb:2LU5|rcsb pdb:2MP3|rcsb pdb:2NAM|rcsb pdb:2NNX|rcsb pdb:2R27|rcsb pdb:2V0A|rcsb pdb:2VR6|rcsb pdb:2VR7|rcsb pdb:2VR8|rcsb pdb:2WKO|rcsb pdb:2WYT|rcsb pdb:2WYZ|rcsb pdb:2WZ0|rcsb pdb:2WZ5|rcsb pdb:2WZ6|rcsb pdb:2XJK|rcsb pdb:2XJL|rcsb pdb:2ZKW|rcsb pdb:2ZKX|rcsb pdb:2ZKY|rcsb pdb:3CQP|rcsb pdb:3CQQ|rcsb pdb:3ECU|rcsb pdb:3ECV|rcsb pdb:3ECW|rcsb pdb:3GQF|rcsb pdb:3GTV|rcsb pdb:3GZO|rcsb pdb:3GZP|rcsb pdb:3GZQ|rcsb pdb:3H2P|rcsb pdb:3H2Q|rcsb pdb:3HFF|rcsb pdb:3K91|rcsb pdb:3KH3|rcsb pdb:3KH4|rcsb pdb:3LTV|rcsb pdb:3QQD|rcsb pdb:3RE0|rcsb pdb:3T5W|rcsb pdb:4A7G|rcsb pdb:4A7Q|rcsb pdb:4A7S|rcsb pdb:4A7T|rcsb pdb:4A7U|rcsb pdb:4A7V|rcsb pdb:4B3E|rcsb pdb:4BCY|rcsb pdb:4BCZ|rcsb pdb:4BD4|rcsb pdb:4FF9|rcsb pdb:4MCM|rcsb pdb:4MCN|rcsb pdb:4NIN|rcsb pdb:4NIO|rcsb pdb:4NIP|rcsb pdb:4OH2|rcsb pdb:4SOD|rcsb pdb:4XCR|rcsb pdb:5DLI|rcsb pdb:5IIW|rcsb pdb:5J07|rcsb pdb:5J0C|rcsb pdb:5J0F|rcsb pdb:5J0G|rcsb pdb:5K02|rcsb pdb:5O3Y|rcsb pdb:5O40|rcsb pdb:5U9M|rcsb pdb:5WOR|rcsb pdb:5YTO|rcsb pdb:5YTU|rcsb pdb:5YUL|rcsb pdb:6A9O|rcsb pdb:6B79|rcsb pdb:6DTK|rcsb pdb:6FFK|rcsb pdb:6FLH|rcsb pdb:6FOI|rcsb pdb:6FOL|rcsb pdb:6FON|rcsb pdb:6FP6|rcsb pdb:6SPA|rcsb pdb:6SPH|rcsb pdb:6SPI|rcsb pdb:6SPJ|rcsb pdb:6SPK|rcsb pdb:6Z3V|rcsb pdb:6Z4G|rcsb pdb:6Z4H|rcsb pdb:6Z4I|rcsb pdb:6Z4J|rcsb pdb:6Z4K|rcsb pdb:6Z4L|rcsb pdb:6Z4M|rcsb pdb:6Z4O|reactome:R-HSA-114608|reactome:R-HSA-3299685|reactome:R-HSA-8950505|rcsb pdb:5WMJ|go:"GO:0046688"(response to copper ion)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0048538"(thymus development)|go:"GO:0048678"(response to axon injury)|go:"GO:0050665"(hydrogen peroxide biosynthetic process)|go:"GO:0046677"(response to antibiotic)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0051087"(chaperone binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0060047"(heart contraction)|go:"GO:0060052"(neurofilament cytoskeleton organization)|go:"GO:0060087"(relaxation of vascular associated smooth muscle)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071318"(cellular response to ATP)|go:"GO:0072593"(reactive oxygen species metabolic process)|go:"GO:0097332"(response to antipsychotic drug)|go:"GO:1902177"(positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR001424(Superoxide dismutase, copper/zinc binding)|refseq:NP_000445.1|dip:DIP-44941N - - comment:"author score: 31" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:W5O3CdnrxKm1kudXW04wxnCxTY09606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:Q9UPN9 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-2214398|uniprotkb:O95855|uniprotkb:Q5TG72|uniprotkb:Q5TG73|uniprotkb:Q5TG74|uniprotkb:Q9C017|uniprotkb:Q9UJ79|ensembl:ENSP00000351250 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:tri33_human(display_long)|uniprotkb:RING-type E3 ubiquitin transferase TRIM33(gene name synonym)|uniprotkb:TRIM33(gene name)|psi-mi:TRIM33(display_short)|uniprotkb:KIAA1113(gene name synonym)|uniprotkb:RFG7(gene name synonym)|uniprotkb:TIF1G(gene name synonym)|uniprotkb:Tripartite motif-containing protein 33(gene name synonym)|uniprotkb:Transcription intermediary factor 1-gamma(gene name synonym)|uniprotkb:Ectodermin homolog(gene name synonym)|uniprotkb:RET-fused gene 7 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_056990.3|refseq:NP_148980.2|ensembl:ENSG00000197323(gene)|ensembl:ENST00000358465(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003677"(DNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017015"(regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0070410"(co-SMAD binding)|go:"GO:0070412"(R-SMAD binding)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR019786|interpro:IPR019787|interpro:IPR027370|interpro:IPR036427|mint:Q9UPN9|rcsb pdb:3U5M|rcsb pdb:3U5N|rcsb pdb:3U5O|rcsb pdb:3U5P|rcsb pdb:5MR8|reactome:R-HSA-2173795|dip:DIP-54262N - - comment:"author score: 34" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:DB02UIWcpeneONPdG17AS08/9/A9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P61956 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-473220|uniprotkb:P55855|uniprotkb:Q6IPZ6|ensembl:ENSP00000405965|uniprotkb:Q32Q42|uniprotkb:Q96HK1|intact:EBI-2512339|uniprotkb:B2R4I2 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:sumo2_human(display_long)|uniprotkb:SMT3 homolog 2(gene name synonym)|uniprotkb:Sentrin-2(gene name synonym)|uniprotkb:HSMT3(gene name synonym)|uniprotkb:SUMO-3(gene name synonym)|uniprotkb:SUMO2(gene name)|psi-mi:SUMO2(display_short)|uniprotkb:SMT3H2(gene name synonym)|uniprotkb:SMT3B(gene name synonym)|uniprotkb:Ubiquitin-like protein SMT3B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) rcsb pdb:1Z5Q|rcsb pdb:2AWT|rcsb pdb:2CKH|rcsb pdb:2D07|go:"GO:0016605"(PML body)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031386"(protein tag)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR000626(Ubiquitin)|interpro:IPR022617|interpro:IPR029071|mint:P61956|rcsb pdb:1WM2|rcsb pdb:1WM3|rcsb pdb:1WZ0|rcsb pdb:2IO0|ensembl:ENSG00000188612(gene)|ensembl:ENST00000420826(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|refseq:NP_001005849.1|refseq:NP_008868.3|rcsb pdb:2IO3|rcsb pdb:6JXW|rcsb pdb:6JXX|reactome:R-HSA-196791|reactome:R-HSA-3065676|reactome:R-HSA-3065678|reactome:R-HSA-3065679|reactome:R-HSA-3108214|reactome:R-HSA-3232118|reactome:R-HSA-3899300|reactome:R-HSA-4085377|reactome:R-HSA-4090294|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5693607|reactome:R-HSA-5696395|rcsb pdb:5GHC|rcsb pdb:5D2M|rcsb pdb:5ELU|rcsb pdb:5EQL|rcsb pdb:5GHB|rcsb pdb:2IYD|rcsb pdb:2N1W|rcsb pdb:2N9E|rcsb pdb:2RPQ|rcsb pdb:3UIN|rcsb pdb:3UIO|rcsb pdb:3ZO5|rcsb pdb:4BKG|rcsb pdb:4NPN|dip:DIP-29253N - - comment:"author score: 34" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:WgudlZhwtQbQInv29BniecTYGY89606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:P62158 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-397435|uniprotkb:P02593|uniprotkb:P70667|uniprotkb:P99014|uniprotkb:Q13942|uniprotkb:Q53S29|uniprotkb:Q61379|uniprotkb:Q61380|uniprotkb:Q96HK3|uniprotkb:P0DP25|uniprotkb:P0DP24|uniprotkb:P0DP23 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:calm_human(display_long)|uniprotkb:CALM1(gene name)|psi-mi:CALM1(display_short)|uniprotkb:CALM(gene name synonym)|uniprotkb:CAM(gene name synonym)|uniprotkb:CAM1(gene name synonym)|uniprotkb:CALM2(gene name)|psi-mi:CALM2(display_short)|uniprotkb:CAMB(gene name synonym)|uniprotkb:CALM3(gene name)|psi-mi:CALM3(display_short)|uniprotkb:CAM3(gene name synonym)|uniprotkb:CAMC(gene name synonym)|uniprotkb:CAMIII(gene name synonym)|uniprotkb:CAM2(gene name synonym)|uniprotkb:CALML2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) rcsb pdb:3SUI|rcsb pdb:2LGF|rcsb pdb:2LQC|rcsb pdb:2LQP|rcsb pdb:2Y4V|rcsb pdb:4JQ0|rcsb pdb:4LZX|rcsb pdb:4M1L|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|rcsb pdb:3J41|rcsb pdb:2LL6|go:"GO:0002027"(regulation of heart rate)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0030017"(sarcomere)|go:"GO:0030801"(obsolete positive regulation of cyclic nucleotide metabolic process)|go:"GO:0032516"(positive regulation of phosphoprotein phosphatase activity)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:1901844"(regulation of cell communication by electrical coupling involved in cardiac conduction)|rcsb pdb:2LV6|rcsb pdb:2N6A|refseq:NP_001734.1|refseq:NP_005175.2|refseq:NP_008819.1|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005876"(spindle microtubule)|go:"GO:0000922"(spindle pole)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005980"(glycogen catabolic process)|go:"GO:0006936"(muscle contraction)|go:"GO:0060315"(negative regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0002576"(platelet degranulation)|go:"GO:0060316"(positive regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0050999"(regulation of nitric-oxide synthase activity)|rcsb pdb:1AJI|rcsb pdb:1CDL|rcsb pdb:1CLL|rcsb pdb:1CTR|rcsb pdb:1IWQ|rcsb pdb:1J7O|rcsb pdb:1J7P|rcsb pdb:1K90|rcsb pdb:1K93|rcsb pdb:1L7Z|rcsb pdb:1LVC|rcsb pdb:1NKF|rcsb pdb:1PK0|rcsb pdb:1S26|rcsb pdb:1SK6|rcsb pdb:1SW8|rcsb pdb:1WRZ|rcsb pdb:1XFU|rcsb pdb:1XFV|rcsb pdb:1XFW|rcsb pdb:1XFX|rcsb pdb:1XFY|rcsb pdb:1XFZ|rcsb pdb:1Y6W|rcsb pdb:1YR5|rcsb pdb:1YRT|rcsb pdb:1YRU|rcsb pdb:1ZOT|rcsb pdb:1ZUZ|rcsb pdb:2BE6|rcsb pdb:2F3Y|rcsb pdb:2F3Z|rcsb pdb:2HF5|rcsb pdb:2I08|rcsb pdb:2JZI|rcsb pdb:2K0E|rcsb pdb:2K0F|rcsb pdb:2K0J|rcsb pdb:2K61|rcsb pdb:2KNE|rcsb pdb:2KUG|rcsb pdb:2KUH|rcsb pdb:2L53|rcsb pdb:2L7L|rcsb pdb:2R28|rcsb pdb:2V01|rcsb pdb:2V02|rcsb pdb:2VAY|rcsb pdb:2W73|rcsb pdb:2WEL|rcsb pdb:2X0G|rcsb pdb:3BYA|rcsb pdb:3DVE|rcsb pdb:3DVJ|rcsb pdb:3DVK|rcsb pdb:3DVM|rcsb pdb:3EWT|rcsb pdb:3EWV|rcsb pdb:3G43|rcsb pdb:3HR4|rcsb pdb:3O77|rcsb pdb:3O78|rcsb pdb:3OXQ|rcsb pdb:3UCT|rcsb pdb:3UCW|rcsb pdb:3UCY|rcsb pdb:4DCK|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0000165"(MAPK cascade)|rcsb pdb:2M0J|rcsb pdb:2M0K|rcsb pdb:4UMO|rcsb pdb:4V0C|go:"GO:0031982"(vesicle)|rcsb pdb:4Q5U|rcsb pdb:4UPU|reactome:R-HSA-2672351|reactome:R-HSA-418359|reactome:R-HSA-425561|reactome:R-HSA-5576892|reactome:R-HSA-5578775|reactome:R-HSA-936837|refseq:NP_001292555.1|rcsb pdb:4OVN|rcsb pdb:5COC|go:"GO:0021762"(substantia nigra development)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:4BW7|rcsb pdb:4BW8|rcsb pdb:4L79|rcsb pdb:5DBR|rcsb pdb:4DJC|rcsb pdb:2M55|rcsb pdb:2LL7|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0001975"(response to amphetamine)|go:"GO:0007190"(activation of adenylate cyclase activity)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030426"(growth cone)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0051412"(response to corticosterone)|go:"GO:1901841"(regulation of high voltage-gated calcium channel activity)|rcsb pdb:2N77|go:"GO:0032991"(protein-containing complex)|go:"GO:0006479"(protein methylation)|go:"GO:0014069"(postsynaptic density)|rcsb pdb:5DSU|reactome:R-HSA-8876725|rcsb pdb:4GOW|rcsb pdb:4Q57|go:"GO:0043647"(inositol phosphate metabolic process)|go:"GO:0022400"(regulation of rhodopsin mediated signaling pathway)|go:"GO:0038095"(Fc-epsilon receptor signaling pathway)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031432"(titin binding)|go:"GO:0031996"(thioesterase binding)|go:"GO:0031997"(N-terminal myristoylation domain binding)|go:"GO:0043274"(phospholipase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055117"(regulation of cardiac muscle contraction)|rcsb pdb:2MG5|go:"GO:0005088"|go:"GO:0007223"(Wnt signaling pathway, calcium modulating pathway)|go:"GO:0008440"(inositol-1,4,5-trisphosphate 3-kinase activity)|go:"GO:0015276"(ligand-gated ion channel activity)|go:"GO:0005634"(nucleus)|rcsb pdb:4JPZ|ensembl:ENST00000272298|ensembl:ENST00000291295|ensembl:ENST00000356978|ensembl:ENST00000596362|refseq:NP_001292553.1|refseq:NP_001292554.1|rcsb pdb:4BYF|reactome:R-HSA-111932|reactome:R-HSA-111933|reactome:R-HSA-111957|reactome:R-HSA-111997|reactome:R-HSA-114608|reactome:R-HSA-1445148|reactome:R-HSA-1474151|reactome:R-HSA-180024|reactome:R-HSA-1855204|reactome:R-HSA-203615|reactome:R-HSA-2514859|reactome:R-HSA-2871809|reactome:R-HSA-4086398|reactome:R-HSA-442717|reactome:R-HSA-442729|reactome:R-HSA-442745|reactome:R-HSA-442982|reactome:R-HSA-445355|reactome:R-HSA-451308|reactome:R-HSA-5218920|reactome:R-HSA-5218921|reactome:R-HSA-5607763|reactome:R-HSA-5626467|reactome:R-HSA-5627123|reactome:R-HSA-5673001|reactome:R-HSA-70221|reactome:R-HSA-983695|ensembl:ENSG00000143933|ensembl:ENSG00000160014|ensembl:ENSG00000198668|ensembl:ENSP00000272298|ensembl:ENSP00000291295|ensembl:ENSP00000349467|ensembl:ENSP00000472141|rcsb pdb:5NIN|rcsb pdb:5VMS|rcsb pdb:5WSU|rcsb pdb:5WSV|rcsb pdb:6U39|rcsb pdb:6U3A|rcsb pdb:6U3B|rcsb pdb:6U3D|rcsb pdb:2N8J|rcsb pdb:5GGM|rcsb pdb:5J8H|reactome:R-HSA-163615|reactome:R-HSA-5210891|refseq:NP_001316851.1|refseq:NP_001316852.1|refseq:NP_001316853.1|refseq:NP_001316854.1|refseq:NP_001316855.1|rcsb pdb:2N27|rcsb pdb:5DOW|rcsb pdb:5I0I|rcsb pdb:5J03|rcsb pdb:5K7L|rcsb pdb:5K8Q|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0043388"(positive regulation of DNA binding)|dip:DIP-31794N|rcsb pdb:1UP5|rcsb pdb:5JQA|rcsb pdb:5JTH|rcsb pdb:5OEO|rcsb pdb:5TP5|rcsb pdb:5TP6|rcsb pdb:5V02|rcsb pdb:5V03|rcsb pdb:5V7X|rcsb pdb:5WBX|rcsb pdb:5WC5|rcsb pdb:6B8L|rcsb pdb:6B8M|rcsb pdb:6B8N|rcsb pdb:6B8P|rcsb pdb:6B8Q|rcsb pdb:6C1D|rcsb pdb:6C1G|rcsb pdb:6C1H|rcsb pdb:6CNM|rcsb pdb:6CNN|rcsb pdb:6CNO|rcsb pdb:6FEG|rcsb pdb:6FEH|reactome:R-HSA-2025928|reactome:R-HSA-2151201|go:"GO:0034704"(calcium channel complex)|go:"GO:0010856"(adenylate cyclase activator activity)|go:"GO:0051186"(obsolete cofactor metabolic process)|go:"GO:0075206"(obsolete positive regulation by host of symbiont cAMP-mediated signal transduction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|interpro:IPR039030|go:"GO:1902494"(catalytic complex)|go:"GO:0043234"|go:"GO:0008179"(adenylate cyclase binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0030819"(obsolete positive regulation of cAMP biosynthetic process)|rcsb pdb:6BUT|rcsb pdb:6DAD|rcsb pdb:6DAE|rcsb pdb:6DAF|rcsb pdb:6DAH|rcsb pdb:6E2F|rcsb pdb:6E2G|rcsb pdb:6EEB|rcsb pdb:6GDK|rcsb pdb:6GDL|rcsb pdb:6HCS|rcsb pdb:6JI8|rcsb pdb:6JII|rcsb pdb:6JIU|rcsb pdb:6JIY|rcsb pdb:6JRS|rcsb pdb:6JV2|rcsb pdb:6K4K|rcsb pdb:6K4L|rcsb pdb:6K4R|rcsb pdb:6MUD|rcsb pdb:6MUE|rcsb pdb:6N5W|rcsb pdb:6O5G|reactome:R-HSA-438066|reactome:R-HSA-442720|reactome:R-HSA-5673000|reactome:R-HSA-6802946|reactome:R-HSA-6802949|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9009391|reactome:R-HSA-9022535|reactome:R-HSA-9022692|reactome:R-HSA-9617324|reactome:R-HSA-9619229|reactome:R-HSA-9619483|reactome:R-HSA-9620244|go:"GO:0019722"(calcium-mediated signaling)|rcsb pdb:6PBX|rcsb pdb:6PBY|reactome:R-HSA-9649948|go:"GO:0005623"(obsolete cell)|rcsb pdb:6HR1|rcsb pdb:6OS4|rcsb pdb:6Y4P|rcsb pdb:6Y94|rcsb pdb:6Y95|reactome:R-HSA-9664323|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0016032"(viral process)|rcsb pdb:6M7H|rcsb pdb:6UZZ|rcsb pdb:6V00|rcsb pdb:6V01|rcsb pdb:6PLM|rcsb pdb:6S5T|rcsb pdb:6SZ5|rcsb pdb:6XXF|rcsb pdb:6Y4O - - comment:"author score: 39" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:tTYcOd9bOh211njZVz7cYVybAMQ9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O15164 uniprotkb:Q5JTW2 intact:EBI-2130378|uniprotkb:O95854|uniprotkb:A4D1R7|uniprotkb:A4D1R8|ensembl:ENSP00000340507 intact:EBI-2562690|uniprotkb:Q9H9N3|uniprotkb:A1A4S8|uniprotkb:Q5JTW1|uniprotkb:Q5JTW0|uniprotkb:Q5BJE3|intact:EBI-10968071|uniprotkb:E9PHX5|ensembl:ENSP00000411284 psi-mi:tif1a_human(display_long)|uniprotkb:TRIM24(gene name)|psi-mi:TRIM24(display_short)|uniprotkb:RNF82(gene name synonym)|uniprotkb:TIF1(gene name synonym)|uniprotkb:TIF1A(gene name synonym)|uniprotkb:Tripartite motif-containing protein 24(gene name synonym)|uniprotkb:RING finger protein 82(gene name synonym)|uniprotkb:E3 ubiquitin-protein ligase TRIM24(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-alpha(gene name synonym) psi-mi:cep78_human(display_long)|uniprotkb:C9orf81(gene name synonym)|uniprotkb:CEP78(gene name)|psi-mi:CEP78(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486121|imex:IM-26985-451 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003843.3|refseq:NP_056989.2|dip:DIP-52713N|ensembl:ENSG00000122779(gene)|ensembl:ENST00000343526(transcript)|go:"GO:0000791"(euchromatin)|go:"GO:0002039"(p53 binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005726"(perichromatin fibrils)|go:"GO:0005829"(cytosol)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0030163"(protein catabolic process)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034056"(estrogen response element binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071391"(cellular response to estrogen stimulus)|go:"GO:1901796"(regulation of signal transduction by p53 class mediator)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR018359|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|mint:O15164|rcsb pdb:2YYN|rcsb pdb:3O33|rcsb pdb:3O34|rcsb pdb:3O35|rcsb pdb:3O36|rcsb pdb:3O37|go:"GO:0055074"(calcium ion homeostasis)|rcsb pdb:4YAB|rcsb pdb:4YAD|rcsb pdb:4YAT|rcsb pdb:4YAX|rcsb pdb:4YBM|rcsb pdb:4YBS|rcsb pdb:4YBT|rcsb pdb:4YC9|rcsb pdb:4ZQL|rcsb pdb:5H1T|rcsb pdb:5H1U|rcsb pdb:5H1V|reactome:R-HSA-1839117|reactome:R-HSA-5655302|reactome:R-HSA-6802952|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070562"(regulation of vitamin D receptor signaling pathway) refseq:NP_001092272.1|refseq:NP_115547.1|refseq:NP_001317620.1|refseq:NP_001317622.1|refseq:NP_001317623.1|ensembl:ENSG00000148019(gene)|ensembl:ENST00000424347(transcript)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0036064"(ciliary basal body)|go:"GO:0044782"(cilium organization)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR026212|interpro:IPR032675|mint:Q5JTW2|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-8854518 - - comment:"author score: 60" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/10/21 rogid:jfxCpemP8t6GF09CXu+bpmfZ2ng9606 rogid:qtqlOeCnHrdYtYUFPxx8aMZ15is9606 rigid:EKnEHFQX8fEyLUe9dNx9uexsRvc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14607 uniprotkb:Q96P63 intact:EBI-3934106|uniprotkb:O14608|uniprotkb:A8K9Z3|intact:EBI-28988456|ensembl:ENSP00000328939|uniprotkb:E1U199|uniprotkb:E1U1A0|uniprotkb:F5H4V7|uniprotkb:F8W8R7 intact:EBI-2553395|uniprotkb:Q3SYB4|ensembl:ENSP00000269491 psi-mi:uty_human(display_long)|uniprotkb:UTY(gene name)|psi-mi:UTY(display_short)|uniprotkb:KDM6C(gene name synonym)|uniprotkb:Ubiquitously-transcribed TPR protein on the Y chromosome(gene name synonym)|uniprotkb:Ubiquitously-transcribed Y chromosome tetratricopeptide repeat protein(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(27) demethylase UTY"(gene name synonym) psi-mi:spb12_human(display_long)|uniprotkb:SERPINB12(gene name)|psi-mi:SERPINB12(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486571|imex:IM-26985-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183878(gene)|ensembl:ENST00000331397(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0071557"(histone H3-K27 demethylation)|go:"GO:0071558"(histone H3-tri/di-methyl-lysine-27 demethylase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:O14607|rcsb pdb:3ZLI|rcsb pdb:3ZPO|rcsb pdb:4UF0|rcsb pdb:5A1L|rcsb pdb:5FXV|rcsb pdb:5FXW|rcsb pdb:5FXX|rcsb pdb:5FXZ|rcsb pdb:5FY0|rcsb pdb:5FY1|rcsb pdb:5FY7|rcsb pdb:5FYM|reactome:R-HSA-3214842|go:"GO:0007507"(heart development)|refseq:NP_009056.3|refseq:NP_872600.1|refseq:NP_872601.1|refseq:NP_001245181.1|refseq:NP_001245183.1|ensembl:ENST00000329134|ensembl:ENSP00000330446|ensembl:ENSP00000328939|ensembl:ENST00000362096|ensembl:ENSP00000355420|ensembl:ENST00000624098|ensembl:ENSP00000485539|ensembl:ENST00000682913|ensembl:ENSP00000507736|dip:DIP-48650N refseq:NP_001294857.1|refseq:XP_011524550.1|refseq:XP_011524551.1|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:Q96P63|reactome:R-HSA-6798695|refseq:NP_536722.1|ensembl:ENSG00000166634(gene)|ensembl:ENST00000269491(transcript)|refseq:XP_016881556.1 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CwoStszULfVOM9pEVWdSRcUXWhY9606 rogid:rjDNYwceRueAXnaDN3nJNMqwRxM9606 rigid:GtPN6wgaX4t6pE4+ttKvOpJ0Py4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14607 uniprotkb:P04196 intact:EBI-3934106|uniprotkb:O14608|uniprotkb:A8K9Z3|intact:EBI-28988456|ensembl:ENSP00000328939|uniprotkb:E1U199|uniprotkb:E1U1A0|uniprotkb:F5H4V7|uniprotkb:F8W8R7 intact:EBI-3915012|uniprotkb:B9EK35|uniprotkb:D3DNU7|ensembl:ENSP00000232003 psi-mi:uty_human(display_long)|uniprotkb:UTY(gene name)|psi-mi:UTY(display_short)|uniprotkb:KDM6C(gene name synonym)|uniprotkb:Ubiquitously-transcribed TPR protein on the Y chromosome(gene name synonym)|uniprotkb:Ubiquitously-transcribed Y chromosome tetratricopeptide repeat protein(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(27) demethylase UTY"(gene name synonym) psi-mi:hrg_human(display_long)|uniprotkb:HRG(gene name)|psi-mi:HRG(display_short)|uniprotkb:Histidine-proline-rich glycoprotein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486571|imex:IM-26985-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183878(gene)|ensembl:ENST00000331397(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0071557"(histone H3-K27 demethylation)|go:"GO:0071558"(histone H3-tri/di-methyl-lysine-27 demethylase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:O14607|rcsb pdb:3ZLI|rcsb pdb:3ZPO|rcsb pdb:4UF0|rcsb pdb:5A1L|rcsb pdb:5FXV|rcsb pdb:5FXW|rcsb pdb:5FXX|rcsb pdb:5FXZ|rcsb pdb:5FY0|rcsb pdb:5FY1|rcsb pdb:5FY7|rcsb pdb:5FYM|reactome:R-HSA-3214842|go:"GO:0007507"(heart development)|refseq:NP_009056.3|refseq:NP_872600.1|refseq:NP_872601.1|refseq:NP_001245181.1|refseq:NP_001245183.1|ensembl:ENST00000329134|ensembl:ENSP00000330446|ensembl:ENSP00000328939|ensembl:ENST00000362096|ensembl:ENSP00000355420|ensembl:ENST00000624098|ensembl:ENSP00000485539|ensembl:ENST00000682913|ensembl:ENSP00000507736|dip:DIP-48650N refseq:NP_000403.1|ensembl:ENSG00000113905(gene)|ensembl:ENST00000232003(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0002839"(positive regulation of immune response to tumor cell)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0006935"(chemotaxis)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0008201"(heparin binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010543"(regulation of platelet activation)|go:"GO:0010593"(negative regulation of lamellipodium assembly)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0015886"(heme transport)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019865"(immunoglobulin binding)|go:"GO:0020037"(heme binding)|go:"GO:0030168"(platelet activation)|go:"GO:0030193"(regulation of blood coagulation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0033629"(negative regulation of cell adhesion mediated by integrin)|go:"GO:0036019"(endolysosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043395"(heparan sulfate proteoglycan binding)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051838"(cytolysis by host of symbiont cells)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0051918"(negative regulation of fibrinolysis)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|go:"GO:2000504"(positive regulation of blood vessel remodeling)|go:"GO:2001027"(negative regulation of endothelial cell chemotaxis)|interpro:IPR000010(Proteinase inhibitor I25, cystatin)|mint:P04196|reactome:R-HSA-114608|reactome:R-HSA-75205|go:"GO:0043254"(regulation of protein-containing complex assembly)|dip:DIP-47264N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CwoStszULfVOM9pEVWdSRcUXWhY9606 rogid:o/MnMkd+IKLRtprrFoOapUuoVEs9606 rigid:GtPN6wgaX4t6pE4+ttKvOpJ0Py4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14607 uniprotkb:P81605 intact:EBI-3934106|uniprotkb:O14608|uniprotkb:A8K9Z3|intact:EBI-28988456|ensembl:ENSP00000328939|uniprotkb:E1U199|uniprotkb:E1U1A0|uniprotkb:F5H4V7|uniprotkb:F8W8R7 intact:EBI-395625|uniprotkb:P58461|uniprotkb:A5JHP2|uniprotkb:A5JHP3|uniprotkb:Q53YJ2|ensembl:ENSP00000293371 psi-mi:uty_human(display_long)|uniprotkb:UTY(gene name)|psi-mi:UTY(display_short)|uniprotkb:KDM6C(gene name synonym)|uniprotkb:Ubiquitously-transcribed TPR protein on the Y chromosome(gene name synonym)|uniprotkb:Ubiquitously-transcribed Y chromosome tetratricopeptide repeat protein(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(27) demethylase UTY"(gene name synonym) psi-mi:dcd_human(display_long)|uniprotkb:AIDD(gene name synonym)|uniprotkb:DSEP(gene name synonym)|uniprotkb:Preproteolysin(gene name synonym)|uniprotkb:DCD(gene name)|psi-mi:DCD(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486571|imex:IM-26985-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183878(gene)|ensembl:ENST00000331397(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0071557"(histone H3-K27 demethylation)|go:"GO:0071558"(histone H3-tri/di-methyl-lysine-27 demethylase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:O14607|rcsb pdb:3ZLI|rcsb pdb:3ZPO|rcsb pdb:4UF0|rcsb pdb:5A1L|rcsb pdb:5FXV|rcsb pdb:5FXW|rcsb pdb:5FXX|rcsb pdb:5FXZ|rcsb pdb:5FY0|rcsb pdb:5FY1|rcsb pdb:5FY7|rcsb pdb:5FYM|reactome:R-HSA-3214842|go:"GO:0007507"(heart development)|refseq:NP_009056.3|refseq:NP_872600.1|refseq:NP_872601.1|refseq:NP_001245181.1|refseq:NP_001245183.1|ensembl:ENST00000329134|ensembl:ENSP00000330446|ensembl:ENSP00000328939|ensembl:ENST00000362096|ensembl:ENSP00000355420|ensembl:ENST00000624098|ensembl:ENSP00000485539|ensembl:ENST00000682913|ensembl:ENSP00000507736|dip:DIP-48650N refseq:NP_444513.1|refseq:NP_001287783.1|ensembl:ENSG00000161634(gene)|ensembl:ENST00000293371(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008233"(peptidase activity)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR028130|interpro:IPR043557|mint:P81605|rcsb pdb:2KSG|rcsb pdb:2NDK|rcsb pdb:2YMK|rcsb pdb:6SHK|reactome:R-HSA-6803157 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CwoStszULfVOM9pEVWdSRcUXWhY9606 rogid:M8PkKVWx98nhtd79ods05mqw8Ls9606 rigid:GtPN6wgaX4t6pE4+ttKvOpJ0Py4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14607 uniprotkb:P61964 intact:EBI-3934106|uniprotkb:O14608|uniprotkb:A8K9Z3|intact:EBI-28988456|ensembl:ENSP00000328939|uniprotkb:E1U199|uniprotkb:E1U1A0|uniprotkb:F5H4V7|uniprotkb:F8W8R7 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 psi-mi:uty_human(display_long)|uniprotkb:UTY(gene name)|psi-mi:UTY(display_short)|uniprotkb:KDM6C(gene name synonym)|uniprotkb:Ubiquitously-transcribed TPR protein on the Y chromosome(gene name synonym)|uniprotkb:Ubiquitously-transcribed Y chromosome tetratricopeptide repeat protein(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(27) demethylase UTY"(gene name synonym) psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486571|imex:IM-26985-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183878(gene)|ensembl:ENST00000331397(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0071557"(histone H3-K27 demethylation)|go:"GO:0071558"(histone H3-tri/di-methyl-lysine-27 demethylase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:O14607|rcsb pdb:3ZLI|rcsb pdb:3ZPO|rcsb pdb:4UF0|rcsb pdb:5A1L|rcsb pdb:5FXV|rcsb pdb:5FXW|rcsb pdb:5FXX|rcsb pdb:5FXZ|rcsb pdb:5FY0|rcsb pdb:5FY1|rcsb pdb:5FY7|rcsb pdb:5FYM|reactome:R-HSA-3214842|go:"GO:0007507"(heart development)|refseq:NP_009056.3|refseq:NP_872600.1|refseq:NP_872601.1|refseq:NP_001245181.1|refseq:NP_001245183.1|ensembl:ENST00000329134|ensembl:ENSP00000330446|ensembl:ENSP00000328939|ensembl:ENST00000362096|ensembl:ENSP00000355420|ensembl:ENST00000624098|ensembl:ENSP00000485539|ensembl:ENST00000682913|ensembl:ENSP00000507736|dip:DIP-48650N refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CwoStszULfVOM9pEVWdSRcUXWhY9606 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rigid:GtPN6wgaX4t6pE4+ttKvOpJ0Py4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14607 uniprotkb:Q8NEZ4 intact:EBI-3934106|uniprotkb:O14608|uniprotkb:A8K9Z3|intact:EBI-28988456|ensembl:ENSP00000328939|uniprotkb:E1U199|uniprotkb:E1U1A0|uniprotkb:F5H4V7|uniprotkb:F8W8R7 intact:EBI-1042997|uniprotkb:Q8NC02|uniprotkb:Q8NDF6|uniprotkb:Q9H9P4|uniprotkb:Q9NR13|uniprotkb:Q9P222|uniprotkb:Q9UDR7|ensembl:ENSP00000262189 psi-mi:uty_human(display_long)|uniprotkb:UTY(gene name)|psi-mi:UTY(display_short)|uniprotkb:KDM6C(gene name synonym)|uniprotkb:Ubiquitously-transcribed TPR protein on the Y chromosome(gene name synonym)|uniprotkb:Ubiquitously-transcribed Y chromosome tetratricopeptide repeat protein(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(27) demethylase UTY"(gene name synonym) psi-mi:kmt2c_human(display_long)|uniprotkb:KMT2C(gene name)|psi-mi:KMT2C(display_short)|uniprotkb:HALR(gene name synonym)|uniprotkb:Homologous to ALR protein(gene name synonym)|uniprotkb:KIAA1506(gene name synonym)|uniprotkb:MLL3(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486571|imex:IM-26985-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183878(gene)|ensembl:ENST00000331397(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0071557"(histone H3-K27 demethylation)|go:"GO:0071558"(histone H3-tri/di-methyl-lysine-27 demethylase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:O14607|rcsb pdb:3ZLI|rcsb pdb:3ZPO|rcsb pdb:4UF0|rcsb pdb:5A1L|rcsb pdb:5FXV|rcsb pdb:5FXW|rcsb pdb:5FXX|rcsb pdb:5FXZ|rcsb pdb:5FY0|rcsb pdb:5FY1|rcsb pdb:5FY7|rcsb pdb:5FYM|reactome:R-HSA-3214842|go:"GO:0007507"(heart development)|refseq:NP_009056.3|refseq:NP_872600.1|refseq:NP_872601.1|refseq:NP_001245181.1|refseq:NP_001245183.1|ensembl:ENST00000329134|ensembl:ENSP00000330446|ensembl:ENSP00000328939|ensembl:ENST00000362096|ensembl:ENSP00000355420|ensembl:ENST00000624098|ensembl:ENSP00000485539|ensembl:ENST00000682913|ensembl:ENSP00000507736|dip:DIP-48650N ensembl:ENSG00000055609(gene)|ensembl:ENST00000262189(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042393"(histone binding)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0097692"(histone H3-K4 monomethylation)|interpro:IPR000637(HMG-I and HMG-Y, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|go:"GO:0005634"(nucleus)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036910|interpro:IPR037877|interpro:IPR041967|interpro:IPR041968|mint:Q8NEZ4|rcsb pdb:2YSM|rcsb pdb:2YUK|rcsb pdb:3UVL|rcsb pdb:4ERY|rcsb pdb:5F59|rcsb pdb:5F6K|rcsb pdb:6KIW|rcsb pdb:6MLC|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8936459|refseq:NP_733751.2|ensembl:ENSP00000262189|ensembl:ENST00000682283|ensembl:ENSP00000507485|dip:DIP-48649N - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CwoStszULfVOM9pEVWdSRcUXWhY9606 rogid:NZg8HgfbohMT8EEgAdAgWR1AjSo9606 rigid:GtPN6wgaX4t6pE4+ttKvOpJ0Py4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14607 uniprotkb:O14686 intact:EBI-3934106|uniprotkb:O14608|uniprotkb:A8K9Z3|intact:EBI-28988456|ensembl:ENSP00000328939|uniprotkb:E1U199|uniprotkb:E1U1A0|uniprotkb:F5H4V7|uniprotkb:F8W8R7 intact:EBI-996065|uniprotkb:O14687|intact:EBI-28986759|ensembl:ENSP00000301067 psi-mi:uty_human(display_long)|uniprotkb:UTY(gene name)|psi-mi:UTY(display_short)|uniprotkb:KDM6C(gene name synonym)|uniprotkb:Ubiquitously-transcribed TPR protein on the Y chromosome(gene name synonym)|uniprotkb:Ubiquitously-transcribed Y chromosome tetratricopeptide repeat protein(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(27) demethylase UTY"(gene name synonym) psi-mi:kmt2d_human(display_long)|uniprotkb:KMT2D(gene name)|psi-mi:KMT2D(display_short)|uniprotkb:ALL1-related protein(gene name synonym)|uniprotkb:ALR(gene name synonym)|uniprotkb:MLL2(gene name synonym)|uniprotkb:MLL4(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486571|imex:IM-26985-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183878(gene)|ensembl:ENST00000331397(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0071557"(histone H3-K27 demethylation)|go:"GO:0071558"(histone H3-tri/di-methyl-lysine-27 demethylase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:O14607|rcsb pdb:3ZLI|rcsb pdb:3ZPO|rcsb pdb:4UF0|rcsb pdb:5A1L|rcsb pdb:5FXV|rcsb pdb:5FXW|rcsb pdb:5FXX|rcsb pdb:5FXZ|rcsb pdb:5FY0|rcsb pdb:5FY1|rcsb pdb:5FY7|rcsb pdb:5FYM|reactome:R-HSA-3214842|go:"GO:0007507"(heart development)|refseq:NP_009056.3|refseq:NP_872600.1|refseq:NP_872601.1|refseq:NP_001245181.1|refseq:NP_001245183.1|ensembl:ENST00000329134|ensembl:ENSP00000330446|ensembl:ENSP00000328939|ensembl:ENST00000362096|ensembl:ENSP00000355420|ensembl:ENST00000624098|ensembl:ENSP00000485539|ensembl:ENST00000682913|ensembl:ENSP00000507736|dip:DIP-48650N refseq:NP_003473.3|refseq:XP_006719677.1|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0043627"(response to estrogen)|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:1904837"(beta-catenin-TCF complex assembly)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR009071(High mobility group box, HMG)|ensembl:ENSG00000167548(gene)|ensembl:ENST00000301067(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001555"(oocyte growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|interpro:IPR036910|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR037890|interpro:IPR041961|interpro:IPR041964|mint:O14686|rcsb pdb:3UVK|rcsb pdb:4ERQ|rcsb pdb:4Z4P|rcsb pdb:6O7G|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR034732|ensembl:ENSP00000301067|refseq:XP_005269219.1|dip:DIP-37875N - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CwoStszULfVOM9pEVWdSRcUXWhY9606 rogid:eaCGHR6OqxzL66VYfOrzBWJApHY9606 rigid:GtPN6wgaX4t6pE4+ttKvOpJ0Py4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14607 uniprotkb:Q15291 intact:EBI-3934106|uniprotkb:O14608|uniprotkb:A8K9Z3|intact:EBI-28988456|ensembl:ENSP00000328939|uniprotkb:E1U199|uniprotkb:E1U1A0|uniprotkb:F5H4V7|uniprotkb:F8W8R7 intact:EBI-592823|uniprotkb:A8K272|uniprotkb:Q7Z6D8|uniprotkb:Q8NDZ7|ensembl:ENSP00000264515 psi-mi:uty_human(display_long)|uniprotkb:UTY(gene name)|psi-mi:UTY(display_short)|uniprotkb:KDM6C(gene name synonym)|uniprotkb:Ubiquitously-transcribed TPR protein on the Y chromosome(gene name synonym)|uniprotkb:Ubiquitously-transcribed Y chromosome tetratricopeptide repeat protein(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(27) demethylase UTY"(gene name synonym) psi-mi:rbbp5_human(display_long)|uniprotkb:Retinoblastoma-binding protein RBQ-3(gene name synonym)|uniprotkb:RBBP5(gene name)|psi-mi:RBBP5(display_short)|uniprotkb:RBQ3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486571|imex:IM-26985-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183878(gene)|ensembl:ENST00000331397(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0071557"(histone H3-K27 demethylation)|go:"GO:0071558"(histone H3-tri/di-methyl-lysine-27 demethylase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:O14607|rcsb pdb:3ZLI|rcsb pdb:3ZPO|rcsb pdb:4UF0|rcsb pdb:5A1L|rcsb pdb:5FXV|rcsb pdb:5FXW|rcsb pdb:5FXX|rcsb pdb:5FXZ|rcsb pdb:5FY0|rcsb pdb:5FY1|rcsb pdb:5FY7|rcsb pdb:5FYM|reactome:R-HSA-3214842|go:"GO:0007507"(heart development)|refseq:NP_009056.3|refseq:NP_872600.1|refseq:NP_872601.1|refseq:NP_001245181.1|refseq:NP_001245183.1|ensembl:ENST00000329134|ensembl:ENSP00000330446|ensembl:ENSP00000328939|ensembl:ENST00000362096|ensembl:ENSP00000355420|ensembl:ENST00000624098|ensembl:ENSP00000485539|ensembl:ENST00000682913|ensembl:ENSP00000507736|dip:DIP-48650N refseq:NP_001180201.1|refseq:NP_001180202.1|refseq:NP_005048.2|dip:DIP-29224N|ensembl:ENSG00000117222(gene)|ensembl:ENST00000264515(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037850|mint:Q15291|rcsb pdb:3P4F|rcsb pdb:4X8N|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6KM7|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6PWX|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664 - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CwoStszULfVOM9pEVWdSRcUXWhY9606 rogid:Zl8yHcbL1C6StHPyD+875Ccy6gk9606 rigid:GtPN6wgaX4t6pE4+ttKvOpJ0Py4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14607 uniprotkb:P02656 intact:EBI-3934106|uniprotkb:O14608|uniprotkb:A8K9Z3|intact:EBI-28988456|ensembl:ENSP00000328939|uniprotkb:E1U199|uniprotkb:E1U1A0|uniprotkb:F5H4V7|uniprotkb:F8W8R7 intact:EBI-1220113|uniprotkb:Q08E83|uniprotkb:Q6Q786|ensembl:ENSP00000227667 psi-mi:uty_human(display_long)|uniprotkb:UTY(gene name)|psi-mi:UTY(display_short)|uniprotkb:KDM6C(gene name synonym)|uniprotkb:Ubiquitously-transcribed TPR protein on the Y chromosome(gene name synonym)|uniprotkb:Ubiquitously-transcribed Y chromosome tetratricopeptide repeat protein(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(27) demethylase UTY"(gene name synonym) psi-mi:apoc3_human(display_long)|uniprotkb:APOC3(gene name)|psi-mi:APOC3(display_short)|uniprotkb:Apolipoprotein C3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486571|imex:IM-26985-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183878(gene)|ensembl:ENST00000331397(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0071557"(histone H3-K27 demethylation)|go:"GO:0071558"(histone H3-tri/di-methyl-lysine-27 demethylase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:O14607|rcsb pdb:3ZLI|rcsb pdb:3ZPO|rcsb pdb:4UF0|rcsb pdb:5A1L|rcsb pdb:5FXV|rcsb pdb:5FXW|rcsb pdb:5FXX|rcsb pdb:5FXZ|rcsb pdb:5FY0|rcsb pdb:5FY1|rcsb pdb:5FY7|rcsb pdb:5FYM|reactome:R-HSA-3214842|go:"GO:0007507"(heart development)|refseq:NP_009056.3|refseq:NP_872600.1|refseq:NP_872601.1|refseq:NP_001245181.1|refseq:NP_001245183.1|ensembl:ENST00000329134|ensembl:ENSP00000330446|ensembl:ENSP00000328939|ensembl:ENST00000362096|ensembl:ENSP00000355420|ensembl:ENST00000624098|ensembl:ENSP00000485539|ensembl:ENST00000682913|ensembl:ENSP00000507736|dip:DIP-48650N refseq:NP_000031.1|ensembl:ENSG00000110245(gene)|ensembl:ENST00000227667(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005769"(early endosome)|go:"GO:0006641"(triglyceride metabolic process)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0010897"(negative regulation of triglyceride catabolic process)|go:"GO:0010903"(negative regulation of very-low-density lipoprotein particle remodeling)|go:"GO:0010916"(negative regulation of very-low-density lipoprotein particle clearance)|go:"GO:0010987"(negative regulation of high-density lipoprotein particle clearance)|go:"GO:0010989"(negative regulation of low-density lipoprotein particle clearance)|go:"GO:0015485"(cholesterol binding)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034363"(intermediate-density lipoprotein particle)|go:"GO:0034366"(spherical high-density lipoprotein particle)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:0034382"(chylomicron remnant clearance)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045717"(negative regulation of fatty acid biosynthetic process)|go:"GO:0045833"(negative regulation of lipid metabolic process)|go:"GO:0048261"(negative regulation of receptor-mediated endocytosis)|go:"GO:0050995"(negative regulation of lipid catabolic process)|go:"GO:0051005"(negative regulation of lipoprotein lipase activity)|go:"GO:0055102"(lipase inhibitor activity)|go:"GO:0060621"(negative regulation of cholesterol import)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070653"(high-density lipoprotein particle receptor binding)|interpro:IPR008403(Apolipoprotein CIII)|interpro:IPR038195|mint:P02656|rcsb pdb:2JQ3|reactome:R-HSA-8963888|reactome:R-HSA-8963901|reactome:R-HSA-8964058|reactome:R-HSA-975634 - - comment:"author score: 27" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CwoStszULfVOM9pEVWdSRcUXWhY9606 rogid:DDj33pQWDh0i5+mwMy16Dmg6JPg9606 rigid:GtPN6wgaX4t6pE4+ttKvOpJ0Py4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O14607 uniprotkb:Q9UBL3 intact:EBI-3934106|uniprotkb:O14608|uniprotkb:A8K9Z3|intact:EBI-28988456|ensembl:ENSP00000328939|uniprotkb:E1U199|uniprotkb:E1U1A0|uniprotkb:F5H4V7|uniprotkb:F8W8R7 intact:EBI-540797|uniprotkb:O60659|uniprotkb:O60660|uniprotkb:Q96B62|ensembl:ENSP00000340896|uniprotkb:A8K7C3|uniprotkb:D3DSW9 psi-mi:uty_human(display_long)|uniprotkb:UTY(gene name)|psi-mi:UTY(display_short)|uniprotkb:KDM6C(gene name synonym)|uniprotkb:Ubiquitously-transcribed TPR protein on the Y chromosome(gene name synonym)|uniprotkb:Ubiquitously-transcribed Y chromosome tetratricopeptide repeat protein(gene name synonym)|uniprotkb:"[histone H3]-trimethyl-L-lysine(27) demethylase UTY"(gene name synonym) psi-mi:ash2l_human(display_long)|uniprotkb:ASH2-like protein(gene name synonym)|uniprotkb:ASH2L(gene name)|psi-mi:ASH2L(display_short)|uniprotkb:ASH2L1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486571|imex:IM-26985-71 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000183878(gene)|ensembl:ENST00000331397(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051213"(dioxygenase activity)|go:"GO:0071557"(histone H3-K27 demethylation)|go:"GO:0071558"(histone H3-tri/di-methyl-lysine-27 demethylase activity)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:O14607|rcsb pdb:3ZLI|rcsb pdb:3ZPO|rcsb pdb:4UF0|rcsb pdb:5A1L|rcsb pdb:5FXV|rcsb pdb:5FXW|rcsb pdb:5FXX|rcsb pdb:5FXZ|rcsb pdb:5FY0|rcsb pdb:5FY1|rcsb pdb:5FY7|rcsb pdb:5FYM|reactome:R-HSA-3214842|go:"GO:0007507"(heart development)|refseq:NP_009056.3|refseq:NP_872600.1|refseq:NP_872601.1|refseq:NP_001245181.1|refseq:NP_001245183.1|ensembl:ENST00000329134|ensembl:ENSP00000330446|ensembl:ENSP00000328939|ensembl:ENST00000362096|ensembl:ENSP00000355420|ensembl:ENST00000624098|ensembl:ENSP00000485539|ensembl:ENST00000682913|ensembl:ENSP00000507736|dip:DIP-48650N refseq:NP_001098684.1|refseq:NP_004665.2|ensembl:ENSG00000129691(gene)|ensembl:ENST00000343823(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0030097"(hemopoiesis)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR037353|mint:Q9UBL3|rcsb pdb:3RSN|rcsb pdb:3S32|rcsb pdb:3TOJ|rcsb pdb:4RIQ|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6E2H|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|rcsb pdb:4X8N|refseq:NP_001248761.1|dip:DIP-29222N - - comment:"author score: 33" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:CwoStszULfVOM9pEVWdSRcUXWhY9606 rogid:ZUYI3M78nGeeb8K2eIiDSw1uWeo9606 rigid:GtPN6wgaX4t6pE4+ttKvOpJ0Py4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TAF3 uniprotkb:Q14011 intact:EBI-1045469|uniprotkb:Q63HJ2|uniprotkb:Q658Y1|uniprotkb:Q8N3Z1|uniprotkb:Q9NSK8|uniprotkb:Q9P279|uniprotkb:B4DM86|uniprotkb:B4DQI2|uniprotkb:B4DY84|ensembl:ENSP00000307491 intact:EBI-538850|uniprotkb:B4E2X2|intact:EBI-10980353|uniprotkb:B3KT17|ensembl:ENSP00000322887|ensembl:ENSP00000465779|ensembl:ENSP00000466110|ensembl:ENSP00000466207|ensembl:ENSP00000468788 psi-mi:wdr48_human(display_long)|uniprotkb:WD repeat endosomal protein(gene name synonym)|uniprotkb:p80(gene name synonym)|uniprotkb:WDR48(gene name)|psi-mi:WDR48(display_short)|uniprotkb:KIAA1449(gene name synonym)|uniprotkb:UAF1(gene name synonym)|uniprotkb:USP1-associated factor 1(gene name synonym) psi-mi:cirbp_human(display_long)|uniprotkb:Glycine-rich RNA-binding protein CIRP(gene name synonym)|uniprotkb:A18 hnRNP(gene name synonym)|uniprotkb:CIRBP(gene name)|psi-mi:CIRBP(display_short)|uniprotkb:A18HNRNP(gene name synonym)|uniprotkb:CIRP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486604|imex:IM-26985-73 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065890.1|ensembl:ENSG00000114742(gene)|ensembl:ENST00000302313(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043588"(skin development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1902525"(regulation of protein monoubiquitination)|go:"GO:1903003"(positive regulation of protein deubiquitination)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021772|interpro:IPR036322|mint:Q8TAF3|rcsb pdb:5CVL|rcsb pdb:5CVN|rcsb pdb:5CVO|rcsb pdb:5K1A|rcsb pdb:5K1B|rcsb pdb:5K1C|rcsb pdb:5L8E|rcsb pdb:5L8W|rcsb pdb:6JLQ|rcsb pdb:7AY0|rcsb pdb:7AY1|rcsb pdb:7AY2|reactome:R-HSA-110314|reactome:R-HSA-5689880|reactome:R-HSA-6783310|reactome:R-HSA-9673766|refseq:NP_001290331.1|refseq:NP_001290332.1|refseq:NP_001333156.1|refseq:NP_001333157.1|dip:DIP-50841N refseq:NP_001271.1|refseq:XP_006722700.1|refseq:NP_001287744.1|refseq:NP_001287758.1|ensembl:ENSG00000099622(gene)|ensembl:ENST00000320936(transcript)|ensembl:ENST00000585630(transcript)|ensembl:ENST00000586472(transcript)|ensembl:ENST00000588030(transcript)|ensembl:ENST00000588090(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0009409"(response to cold)|go:"GO:0009411"(response to UV)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0030371"(translation repressor activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034278|interpro:IPR035979|mint:Q14011|rcsb pdb:1X5S|rcsb pdb:5TBX - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:S8ihl3jxEEyMS46AM2ynXSFfCU49606 rogid:nm6/8k5Pw1AnoXsSw9cazJkL49U9606 rigid:C5/ffuemHWIJxP2+Ds6VixEAsHY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TAF3 uniprotkb:P50990 intact:EBI-1045469|uniprotkb:Q63HJ2|uniprotkb:Q658Y1|uniprotkb:Q8N3Z1|uniprotkb:Q9NSK8|uniprotkb:Q9P279|uniprotkb:B4DM86|uniprotkb:B4DQI2|uniprotkb:B4DY84|ensembl:ENSP00000307491 intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788 psi-mi:wdr48_human(display_long)|uniprotkb:WD repeat endosomal protein(gene name synonym)|uniprotkb:p80(gene name synonym)|uniprotkb:WDR48(gene name)|psi-mi:WDR48(display_short)|uniprotkb:KIAA1449(gene name synonym)|uniprotkb:UAF1(gene name synonym)|uniprotkb:USP1-associated factor 1(gene name synonym) psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486604|imex:IM-26985-73 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065890.1|ensembl:ENSG00000114742(gene)|ensembl:ENST00000302313(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043588"(skin development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1902525"(regulation of protein monoubiquitination)|go:"GO:1903003"(positive regulation of protein deubiquitination)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021772|interpro:IPR036322|mint:Q8TAF3|rcsb pdb:5CVL|rcsb pdb:5CVN|rcsb pdb:5CVO|rcsb pdb:5K1A|rcsb pdb:5K1B|rcsb pdb:5K1C|rcsb pdb:5L8E|rcsb pdb:5L8W|rcsb pdb:6JLQ|rcsb pdb:7AY0|rcsb pdb:7AY1|rcsb pdb:7AY2|reactome:R-HSA-110314|reactome:R-HSA-5689880|reactome:R-HSA-6783310|reactome:R-HSA-9673766|refseq:NP_001290331.1|refseq:NP_001290332.1|refseq:NP_001333156.1|refseq:NP_001333157.1|dip:DIP-50841N refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:S8ihl3jxEEyMS46AM2ynXSFfCU49606 rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606 rigid:C5/ffuemHWIJxP2+Ds6VixEAsHY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TAF3 uniprotkb:Q7Z7K6 intact:EBI-1045469|uniprotkb:Q63HJ2|uniprotkb:Q658Y1|uniprotkb:Q8N3Z1|uniprotkb:Q9NSK8|uniprotkb:Q9P279|uniprotkb:B4DM86|uniprotkb:B4DQI2|uniprotkb:B4DY84|ensembl:ENSP00000307491 intact:EBI-1210604|uniprotkb:Q3L8N5|uniprotkb:Q8NFH6|uniprotkb:B2RPK2 psi-mi:wdr48_human(display_long)|uniprotkb:WD repeat endosomal protein(gene name synonym)|uniprotkb:p80(gene name synonym)|uniprotkb:WDR48(gene name)|psi-mi:WDR48(display_short)|uniprotkb:KIAA1449(gene name synonym)|uniprotkb:UAF1(gene name synonym)|uniprotkb:USP1-associated factor 1(gene name synonym) psi-mi:cenpv_human(display_long)|uniprotkb:CENPV(gene name)|psi-mi:CENPV(display_short)|uniprotkb:Nuclear protein p30(gene name synonym)|uniprotkb:PRR6(gene name synonym)|uniprotkb:Proline-rich protein 6(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486604|imex:IM-26985-73 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065890.1|ensembl:ENSG00000114742(gene)|ensembl:ENST00000302313(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043588"(skin development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1902525"(regulation of protein monoubiquitination)|go:"GO:1903003"(positive regulation of protein deubiquitination)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021772|interpro:IPR036322|mint:Q8TAF3|rcsb pdb:5CVL|rcsb pdb:5CVN|rcsb pdb:5CVO|rcsb pdb:5K1A|rcsb pdb:5K1B|rcsb pdb:5K1C|rcsb pdb:5L8E|rcsb pdb:5L8W|rcsb pdb:6JLQ|rcsb pdb:7AY0|rcsb pdb:7AY1|rcsb pdb:7AY2|reactome:R-HSA-110314|reactome:R-HSA-5689880|reactome:R-HSA-6783310|reactome:R-HSA-9673766|refseq:NP_001290331.1|refseq:NP_001290332.1|refseq:NP_001333156.1|refseq:NP_001333157.1|dip:DIP-50841N refseq:NP_859067.2|interpro:IPR006913(Glutathione-dependent formaldehyde-activating, GFA)|interpro:IPR011057(Mss4-like)|mint:Q7Z7K6|go:"GO:0000776"(kinetochore)|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007049"(cell cycle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016846"(carbon-sulfur lyase activity)|go:"GO:0030496"(midbody)|go:"GO:0031508"(pericentric heterochromatin assembly)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0033044"(regulation of chromosome organization)|go:"GO:0034508"(centromere complex assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0005829"(cytosol) - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:S8ihl3jxEEyMS46AM2ynXSFfCU49606 rogid:q2Dt9PEcUigyqjqFMVm3dxk54B09606 rigid:C5/ffuemHWIJxP2+Ds6VixEAsHY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TAF3 uniprotkb:Q9Y3C1 intact:EBI-1045469|uniprotkb:Q63HJ2|uniprotkb:Q658Y1|uniprotkb:Q8N3Z1|uniprotkb:Q9NSK8|uniprotkb:Q9P279|uniprotkb:B4DM86|uniprotkb:B4DQI2|uniprotkb:B4DY84|ensembl:ENSP00000307491 intact:EBI-5453434|uniprotkb:Q6IAI6|uniprotkb:Q8IXL5|uniprotkb:Q6PIM0|uniprotkb:B4DV13|uniprotkb:D6RGD3|uniprotkb:Q05D05|ensembl:ENSP00000480832 psi-mi:wdr48_human(display_long)|uniprotkb:WD repeat endosomal protein(gene name synonym)|uniprotkb:p80(gene name synonym)|uniprotkb:WDR48(gene name)|psi-mi:WDR48(display_short)|uniprotkb:KIAA1449(gene name synonym)|uniprotkb:UAF1(gene name synonym)|uniprotkb:USP1-associated factor 1(gene name synonym) psi-mi:nop16_human(display_long)|uniprotkb:NOP16(gene name)|psi-mi:NOP16(display_short)|uniprotkb:HBV pre-S2 trans-regulated protein 3(gene name synonym)|uniprotkb:CGI-117(orf name)|uniprotkb:HSPC111(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486604|imex:IM-26985-73 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065890.1|ensembl:ENSG00000114742(gene)|ensembl:ENST00000302313(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043588"(skin development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1902525"(regulation of protein monoubiquitination)|go:"GO:1903003"(positive regulation of protein deubiquitination)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021772|interpro:IPR036322|mint:Q8TAF3|rcsb pdb:5CVL|rcsb pdb:5CVN|rcsb pdb:5CVO|rcsb pdb:5K1A|rcsb pdb:5K1B|rcsb pdb:5K1C|rcsb pdb:5L8E|rcsb pdb:5L8W|rcsb pdb:6JLQ|rcsb pdb:7AY0|rcsb pdb:7AY1|rcsb pdb:7AY2|reactome:R-HSA-110314|reactome:R-HSA-5689880|reactome:R-HSA-6783310|reactome:R-HSA-9673766|refseq:NP_001290331.1|refseq:NP_001290332.1|refseq:NP_001333156.1|refseq:NP_001333157.1|dip:DIP-50841N refseq:NP_057475.2|refseq:NP_001304904.1|refseq:NP_001243468.2|refseq:NP_001278234.1|refseq:NP_001278236.1|refseq:NP_001278237.1|refseq:NP_001243469.2|ensembl:ENSG00000048162(gene)|ensembl:ENST00000614830(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019002|mint:Q9Y3C1 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:S8ihl3jxEEyMS46AM2ynXSFfCU49606 rogid:HdIqgMgye+B+sa3XiPdqvLXbcR89606 rigid:C5/ffuemHWIJxP2+Ds6VixEAsHY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TAF3 uniprotkb:Q8TDD1 intact:EBI-1045469|uniprotkb:Q63HJ2|uniprotkb:Q658Y1|uniprotkb:Q8N3Z1|uniprotkb:Q9NSK8|uniprotkb:Q9P279|uniprotkb:B4DM86|uniprotkb:B4DQI2|uniprotkb:B4DY84|ensembl:ENSP00000307491 intact:EBI-1052503|uniprotkb:Q86YT8|uniprotkb:Q9BRZ1|ensembl:ENSP00000304072 psi-mi:wdr48_human(display_long)|uniprotkb:WD repeat endosomal protein(gene name synonym)|uniprotkb:p80(gene name synonym)|uniprotkb:WDR48(gene name)|psi-mi:WDR48(display_short)|uniprotkb:KIAA1449(gene name synonym)|uniprotkb:UAF1(gene name synonym)|uniprotkb:USP1-associated factor 1(gene name synonym) psi-mi:ddx54_human(display_long)|uniprotkb:DEAD box protein 54(gene name synonym)|uniprotkb:ATP-dependent RNA helicase DP97(gene name synonym)|uniprotkb:DEAD box RNA helicase 97 kDa(gene name synonym)|uniprotkb:DDX54(gene name)|psi-mi:DDX54(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486604|imex:IM-26985-73 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065890.1|ensembl:ENSG00000114742(gene)|ensembl:ENST00000302313(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043588"(skin development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1902525"(regulation of protein monoubiquitination)|go:"GO:1903003"(positive regulation of protein deubiquitination)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021772|interpro:IPR036322|mint:Q8TAF3|rcsb pdb:5CVL|rcsb pdb:5CVN|rcsb pdb:5CVO|rcsb pdb:5K1A|rcsb pdb:5K1B|rcsb pdb:5K1C|rcsb pdb:5L8E|rcsb pdb:5L8W|rcsb pdb:6JLQ|rcsb pdb:7AY0|rcsb pdb:7AY1|rcsb pdb:7AY2|reactome:R-HSA-110314|reactome:R-HSA-5689880|reactome:R-HSA-6783310|reactome:R-HSA-9673766|refseq:NP_001290331.1|refseq:NP_001290332.1|refseq:NP_001333156.1|refseq:NP_001333157.1|dip:DIP-50841N refseq:NP_001104792.1|refseq:NP_076977.3|ensembl:ENSG00000123064(gene)|ensembl:ENST00000306014(transcript)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006364"(rRNA processing)|go:"GO:0006396"(RNA processing)|go:"GO:0016020"(membrane)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012541(DBP10CT)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|interpro:IPR033517|mint:Q8TDD1|go:"GO:0003724"(RNA helicase activity) - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:S8ihl3jxEEyMS46AM2ynXSFfCU49606 rogid:VzxEkRaOIND08jGJk3yyoztesjo9606 rigid:C5/ffuemHWIJxP2+Ds6VixEAsHY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TAF3 uniprotkb:O75317 intact:EBI-1045469|uniprotkb:Q63HJ2|uniprotkb:Q658Y1|uniprotkb:Q8N3Z1|uniprotkb:Q9NSK8|uniprotkb:Q9P279|uniprotkb:B4DM86|uniprotkb:B4DQI2|uniprotkb:B4DY84|ensembl:ENSP00000307491 intact:EBI-2511507|ensembl:ENSP00000282344|uniprotkb:Q8TC49|uniprotkb:Q5VZV3|uniprotkb:A8K0X0 psi-mi:wdr48_human(display_long)|uniprotkb:WD repeat endosomal protein(gene name synonym)|uniprotkb:p80(gene name synonym)|uniprotkb:WDR48(gene name)|psi-mi:WDR48(display_short)|uniprotkb:KIAA1449(gene name synonym)|uniprotkb:UAF1(gene name synonym)|uniprotkb:USP1-associated factor 1(gene name synonym) psi-mi:ubp12_human(display_long)|uniprotkb:USP12(gene name)|psi-mi:USP12(display_short)|uniprotkb:UBH1(gene name synonym)|uniprotkb:USP12L1(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 12(gene name synonym)|uniprotkb:Deubiquitinating enzyme 12(gene name synonym)|uniprotkb:Ubiquitin-hydrolyzing enzyme 1(gene name synonym)|uniprotkb:Ubiquitin thioesterase 12(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486604|imex:IM-26985-73 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065890.1|ensembl:ENSG00000114742(gene)|ensembl:ENST00000302313(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043588"(skin development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1902525"(regulation of protein monoubiquitination)|go:"GO:1903003"(positive regulation of protein deubiquitination)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021772|interpro:IPR036322|mint:Q8TAF3|rcsb pdb:5CVL|rcsb pdb:5CVN|rcsb pdb:5CVO|rcsb pdb:5K1A|rcsb pdb:5K1B|rcsb pdb:5K1C|rcsb pdb:5L8E|rcsb pdb:5L8W|rcsb pdb:6JLQ|rcsb pdb:7AY0|rcsb pdb:7AY1|rcsb pdb:7AY2|reactome:R-HSA-110314|reactome:R-HSA-5689880|reactome:R-HSA-6783310|reactome:R-HSA-9673766|refseq:NP_001290331.1|refseq:NP_001290332.1|refseq:NP_001333156.1|refseq:NP_001333157.1|dip:DIP-50841N ensembl:ENSG00000152484(gene)|ensembl:ENST00000282344(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0046872"(metal ion binding)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765|mint:O75317|rcsb pdb:5K16|rcsb pdb:5K1A|rcsb pdb:5K1B|rcsb pdb:5K1C|rcsb pdb:5L8W|reactome:R-HSA-5689880|refseq:NP_872294.2 - - comment:"author score: 28" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:S8ihl3jxEEyMS46AM2ynXSFfCU49606 rogid:SiueMBicjAsFl2OGlBfQ6tg1cf89606 rigid:C5/ffuemHWIJxP2+Ds6VixEAsHY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TAF3 uniprotkb:Q8TBZ3 intact:EBI-1045469|uniprotkb:Q63HJ2|uniprotkb:Q658Y1|uniprotkb:Q8N3Z1|uniprotkb:Q9NSK8|uniprotkb:Q9P279|uniprotkb:B4DM86|uniprotkb:B4DQI2|uniprotkb:B4DY84|ensembl:ENSP00000307491 intact:EBI-2511486|ensembl:ENSP00000341037|uniprotkb:Q8WXX2|uniprotkb:Q9UF86|uniprotkb:Q8NCN7|intact:EBI-11109494|uniprotkb:H0YJJ1|uniprotkb:Q86TU2|uniprotkb:B4DN18|uniprotkb:E7EUY8|uniprotkb:F8W9S4|uniprotkb:G3V2F8|uniprotkb:G3V5R0 psi-mi:wdr48_human(display_long)|uniprotkb:WD repeat endosomal protein(gene name synonym)|uniprotkb:p80(gene name synonym)|uniprotkb:WDR48(gene name)|psi-mi:WDR48(display_short)|uniprotkb:KIAA1449(gene name synonym)|uniprotkb:UAF1(gene name synonym)|uniprotkb:USP1-associated factor 1(gene name synonym) psi-mi:wdr20_human(display_long)|uniprotkb:WDR20(gene name)|psi-mi:WDR20(display_short)|uniprotkb:Protein DMR(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486604|imex:IM-26985-73 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065890.1|ensembl:ENSG00000114742(gene)|ensembl:ENST00000302313(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043588"(skin development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1902525"(regulation of protein monoubiquitination)|go:"GO:1903003"(positive regulation of protein deubiquitination)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021772|interpro:IPR036322|mint:Q8TAF3|rcsb pdb:5CVL|rcsb pdb:5CVN|rcsb pdb:5CVO|rcsb pdb:5K1A|rcsb pdb:5K1B|rcsb pdb:5K1C|rcsb pdb:5L8E|rcsb pdb:5L8W|rcsb pdb:6JLQ|rcsb pdb:7AY0|rcsb pdb:7AY1|rcsb pdb:7AY2|reactome:R-HSA-110314|reactome:R-HSA-5689880|reactome:R-HSA-6783310|reactome:R-HSA-9673766|refseq:NP_001290331.1|refseq:NP_001290332.1|refseq:NP_001333156.1|refseq:NP_001333157.1|dip:DIP-50841N ensembl:ENSG00000140153(gene)|ensembl:ENST00000342702(transcript)|go:"GO:0005654"(nucleoplasm)|interpro:IPR001680(WD40 repeat)|interpro:IPR036322|mint:Q8TBZ3|rcsb pdb:5K19|rcsb pdb:5K1C|rcsb pdb:6JLQ|reactome:R-HSA-5689880|refseq:NP_001229343.1|refseq:NP_001229345.1|refseq:NP_001229346.1|refseq:NP_001229347.1|refseq:NP_653175.2|refseq:NP_851808.1|refseq:NP_851825.1|refseq:NP_001229344.1 - - comment:"author score: 74" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:S8ihl3jxEEyMS46AM2ynXSFfCU49606 rogid:2MfZps9YU8xQbWazkq2sIqXjHHg9606 rigid:C5/ffuemHWIJxP2+Ds6VixEAsHY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TAF3 uniprotkb:O94782 intact:EBI-1045469|uniprotkb:Q63HJ2|uniprotkb:Q658Y1|uniprotkb:Q8N3Z1|uniprotkb:Q9NSK8|uniprotkb:Q9P279|uniprotkb:B4DM86|uniprotkb:B4DQI2|uniprotkb:B4DY84|ensembl:ENSP00000307491 intact:EBI-2513396|ensembl:ENSP00000343526|ensembl:ENSP00000360188|uniprotkb:Q9UNJ3|uniprotkb:A0PJ95|uniprotkb:Q9UFR0|uniprotkb:Q59H66|uniprotkb:Q05BX7|uniprotkb:D3DQ57 psi-mi:wdr48_human(display_long)|uniprotkb:WD repeat endosomal protein(gene name synonym)|uniprotkb:p80(gene name synonym)|uniprotkb:WDR48(gene name)|psi-mi:WDR48(display_short)|uniprotkb:KIAA1449(gene name synonym)|uniprotkb:UAF1(gene name synonym)|uniprotkb:USP1-associated factor 1(gene name synonym) psi-mi:ubp1_human(display_long)|uniprotkb:USP1(gene name)|psi-mi:USP1(display_short)|uniprotkb:Ubiquitin-specific-processing protease 1(gene name synonym)|uniprotkb:Deubiquitinating enzyme 1(gene name synonym)|uniprotkb:Ubiquitin thioesterase 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486604|imex:IM-26985-73 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065890.1|ensembl:ENSG00000114742(gene)|ensembl:ENST00000302313(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043588"(skin development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1902525"(regulation of protein monoubiquitination)|go:"GO:1903003"(positive regulation of protein deubiquitination)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021772|interpro:IPR036322|mint:Q8TAF3|rcsb pdb:5CVL|rcsb pdb:5CVN|rcsb pdb:5CVO|rcsb pdb:5K1A|rcsb pdb:5K1B|rcsb pdb:5K1C|rcsb pdb:5L8E|rcsb pdb:5L8W|rcsb pdb:6JLQ|rcsb pdb:7AY0|rcsb pdb:7AY1|rcsb pdb:7AY2|reactome:R-HSA-110314|reactome:R-HSA-5689880|reactome:R-HSA-6783310|reactome:R-HSA-9673766|refseq:NP_001290331.1|refseq:NP_001290332.1|refseq:NP_001333156.1|refseq:NP_001333157.1|dip:DIP-50841N ensembl:ENSG00000162607(gene)|ensembl:ENST00000339950(transcript)|ensembl:ENST00000371146(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008233"(peptidase activity)|go:"GO:0009411"(response to UV)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR033815|interpro:IPR038765|mint:O94782|rcsb pdb:6DO5|rcsb pdb:7AY0|rcsb pdb:7AY1|rcsb pdb:7AY2|reactome:R-HSA-110314|reactome:R-HSA-6783310|refseq:NP_001017415.1|refseq:NP_001017416.1|refseq:NP_003359.3|dip:DIP-53609N - - comment:"author score: 84" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:S8ihl3jxEEyMS46AM2ynXSFfCU49606 rogid:cSWX5JiI+vqbREjhCJeCGAiiVzE9606 rigid:C5/ffuemHWIJxP2+Ds6VixEAsHY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8TAF3 uniprotkb:P62068 intact:EBI-1045469|uniprotkb:Q63HJ2|uniprotkb:Q658Y1|uniprotkb:Q8N3Z1|uniprotkb:Q9NSK8|uniprotkb:Q9P279|uniprotkb:B4DM86|uniprotkb:B4DQI2|uniprotkb:B4DY84|ensembl:ENSP00000307491 intact:EBI-2512753|ensembl:ENSP00000407818|uniprotkb:B7Z675|uniprotkb:Q9H7U4|uniprotkb:B7Z7S3|uniprotkb:B7Z3Y7|uniprotkb:Q80V95|uniprotkb:Q9H9T8|uniprotkb:G8ACC7 psi-mi:wdr48_human(display_long)|uniprotkb:WD repeat endosomal protein(gene name synonym)|uniprotkb:p80(gene name synonym)|uniprotkb:WDR48(gene name)|psi-mi:WDR48(display_short)|uniprotkb:KIAA1449(gene name synonym)|uniprotkb:UAF1(gene name synonym)|uniprotkb:USP1-associated factor 1(gene name synonym) psi-mi:ubp46_human(display_long)|uniprotkb:USP46(gene name)|psi-mi:USP46(display_short)|uniprotkb:Ubiquitin-specific-processing protease 46(gene name synonym)|uniprotkb:Deubiquitinating enzyme 46(gene name synonym)|uniprotkb:Ubiquitin thioesterase 46(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486604|imex:IM-26985-73 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_065890.1|ensembl:ENSG00000114742(gene)|ensembl:ENST00000302313(transcript)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0003677"(DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043588"(skin development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0048872"(homeostasis of number of cells)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0072520"(seminiferous tubule development)|go:"GO:1902525"(regulation of protein monoubiquitination)|go:"GO:1903003"(positive regulation of protein deubiquitination)|go:"GO:1905168"(positive regulation of double-strand break repair via homologous recombination)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR021772|interpro:IPR036322|mint:Q8TAF3|rcsb pdb:5CVL|rcsb pdb:5CVN|rcsb pdb:5CVO|rcsb pdb:5K1A|rcsb pdb:5K1B|rcsb pdb:5K1C|rcsb pdb:5L8E|rcsb pdb:5L8W|rcsb pdb:6JLQ|rcsb pdb:7AY0|rcsb pdb:7AY1|rcsb pdb:7AY2|reactome:R-HSA-110314|reactome:R-HSA-5689880|reactome:R-HSA-6783310|reactome:R-HSA-9673766|refseq:NP_001290331.1|refseq:NP_001290332.1|refseq:NP_001333156.1|refseq:NP_001333157.1|dip:DIP-50841N ensembl:ENSG00000109189(gene)|ensembl:ENST00000441222(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008343"(adult feeding behavior)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0032228"(regulation of synaptic transmission, GABAergic)|go:"GO:0046872"(metal ion binding)|go:"GO:0048149"(behavioral response to ethanol)|go:"GO:0060013"(righting reflex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765|mint:P62068|rcsb pdb:5CVM|rcsb pdb:5CVN|rcsb pdb:5CVO|rcsb pdb:5L8H|rcsb pdb:6JLQ|refseq:NP_001273696.1|refseq:NP_001273697.1|refseq:NP_001127695.1|refseq:NP_073743.2|dip:DIP-53590N - - comment:"author score: 103" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:S8ihl3jxEEyMS46AM2ynXSFfCU49606 rogid:MYmLwHkGXhvq+vVvr88amlicCbg9606 rigid:C5/ffuemHWIJxP2+Ds6VixEAsHY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O95816 uniprotkb:Q96CW5 intact:EBI-355275|uniprotkb:Q08AS9|uniprotkb:Q6FID0|uniprotkb:B4DXE2|ensembl:ENSP00000359727|intact:EBI-11068407 intact:EBI-1046278|ensembl:ENSP00000261965|uniprotkb:O43631|uniprotkb:O60852|uniprotkb:O60853|uniprotkb:Q7Z4K1|uniprotkb:Q96I79|uniprotkb:Q5T8L2 psi-mi:bag2_human(display_long)|uniprotkb:BAG2(gene name)|psi-mi:BAG2(display_short)|uniprotkb:Bcl-2-associated athanogene 2(gene name synonym) psi-mi:gcp3_human(display_long)|uniprotkb:Spindle pole body protein Spc98 homolog(gene name synonym)|uniprotkb:TUBGCP3(gene name)|psi-mi:TUBGCP3(display_short)|uniprotkb:GCP3(gene name synonym)|uniprotkb:Gamma-ring complex protein 104 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25486475|imex:IM-26985-217 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004273.1|refseq:XP_011513301.1|refseq:XP_005249547.1|ensembl:ENSG00000112208(gene)|ensembl:ENST00000370693(transcript)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0048156"(tau protein binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0019538"(protein metabolic process)|go:"GO:0051087"(chaperone binding)|go:"GO:0101031"(chaperone complex)|go:"GO:1901588"(dendritic microtubule)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1904667"(negative regulation of ubiquitin protein ligase activity)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR037689|mint:O95816|reactome:R-HSA-3371453|refseq:XP_011513300.1 go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005819"(spindle)|go:"GO:0005827"(polar microtubule)|go:"GO:0005829"(cytosol)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007338"(single fertilization)|go:"GO:0008275"(gamma-tubulin small complex)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|mint:Q96CW5|rcsb pdb:6V6B|go:"GO:0000930"(gamma-tubulin complex)|rcsb pdb:6V6S|rcsb pdb:6X0U|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320|ensembl:ENSG00000126216(gene)|ensembl:ENST00000261965(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000923"(equatorial microtubule organizing center)|refseq:NP_006313.1|refseq:NP_001273207.1|refseq:NP_001273208.1|refseq:NP_001273206.1 - comment:"author score: 12" - figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:nBGGBIQc/3P0mwp7N/XuTGLOrg89606 rogid:xt+Ngo2s/4djh2PnyMEaxgDyLrs9606 rigid:F2XaQ83VzKP3j7+bp59llql8RYE false - tandem tag:n-n - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14157 uniprotkb:Q6NYC1 intact:EBI-347762|uniprotkb:Q5VU75|uniprotkb:Q5VU76|uniprotkb:Q9BTU3|uniprotkb:Q9UGL2|uniprotkb:Q9UGL3|uniprotkb:Q9UGL5|uniprotkb:B4E0U8|uniprotkb:Q9UGL4|ensembl:ENSP00000355343|ensembl:ENSP00000389445 intact:EBI-8464037|uniprotkb:Q9Y4E2|uniprotkb:B4DGX1|uniprotkb:Q8IUM5|uniprotkb:B3KMN8|intact:MINT-3086431|uniprotkb:Q86VY0|ensembl:ENSP00000380750 psi-mi:ubp2l_human(display_long)|uniprotkb:UBAP2L(gene name)|psi-mi:UBAP2L(display_short)|uniprotkb:Protein NICE-4(gene name synonym)|uniprotkb:KIAA0144(gene name synonym)|uniprotkb:NICE4(gene name synonym) psi-mi:jmjd6_human(display_long)|uniprotkb:PTDSR(gene name synonym)|uniprotkb:KIAA0585(gene name synonym)|uniprotkb:JMJD6(gene name)|psi-mi:JMJD6(display_short)|uniprotkb:Histone arginine demethylase JMJD6(gene name synonym)|uniprotkb:JmjC domain-containing protein 6(gene name synonym)|uniprotkb:Jumonji domain-containing protein 6(gene name synonym)|uniprotkb:Lysyl-hydroxylase JMJD6(gene name synonym)|uniprotkb:Peptide-lysine 5-dioxygenase JMJD6(gene name synonym)|uniprotkb:Phosphatidylserine receptor(gene name synonym)|uniprotkb:PSR(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486538|imex:IM-26985-453 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011508518.1|refseq:NP_001120792.1|refseq:NP_055662.3|refseq:NP_001274744.1|refseq:NP_001274745.1|refseq:XP_005245731.1|refseq:XP_016858467.1|refseq:XP_016858468.1|refseq:XP_016858475.1|refseq:XP_016858476.1|refseq:XP_016858478.1|refseq:XP_016858479.1|ensembl:ENSG00000143569(gene)|ensembl:ENST00000361546(transcript)|ensembl:ENST00000428931(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0031519"(PcG protein complex)|go:"GO:0034063"(stress granule assembly)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR022166|mint:Q14157 refseq:NP_055982.2|refseq:NP_001074930.1|dip:DIP-60686N|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006482"(protein demethylation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007507"(heart development)|go:"GO:0008380"(RNA splicing)|go:"GO:0018395"(peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine)|go:"GO:0005506"(iron ion binding)|go:"GO:0030324"(lung development)|go:"GO:0032451"(demethylase activity)|go:"GO:0032452"(histone demethylase activity)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033746"(histone H3-methyl-arginine-2 demethylase activity)|go:"GO:0033749"(histone H3-methyl-arginine-3 demethylase activity)|go:"GO:0035513"(oxidative RNA demethylation)|go:"GO:0035515"(oxidative RNA demethylase activity)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042116"(macrophage activation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048821"(erythrocyte development)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070078"(histone H3-R2 demethylation)|go:"GO:0070079"(histone H4-R3 demethylation)|go:"GO:0070815"(peptidyl-lysine 5-dioxygenase activity)|go:"GO:0106140"(P-TEFb complex binding)|go:"GO:0140537"(transcription regulator activator activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003347(Transcription factor jumonji/aspartyl beta-hydroxylase)|mint:Q6NYC1|rcsb pdb:3K2O|rcsb pdb:3LD8|rcsb pdb:3LDB|rcsb pdb:6BNH|go:"GO:0043654"(recognition of apoptotic cell)|rcsb pdb:6MEV|reactome:R-HSA-3214842|rcsb pdb:6GDY|ensembl:ENSG00000070495(gene)|ensembl:ENST00000397625(transcript)|go:"GO:0001822"(kidney development)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003727"(single-stranded RNA binding) - - comment:mint|comment:homomint|function:Arginine demethylase which demethylates histone H3 at 'Arg-3' and histone H4 at 'Arg-4'. Required for differentiation of multiple organs during embryogenesis. Probably acts as a key regulator of hematopoietic differentiation. Seems to be necessary for the regulation of macrophage cytokine responses|comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:4iKY4hJOHGSyOOt8zfPhkeyth6Q9606 rogid:YbwfNgf/c4ug+02lkCn2C4tMLEI9606 rigid:zLbdK7byEkvtUqOz+2A58LnSbi0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14157 uniprotkb:P51114 intact:EBI-347762|uniprotkb:Q5VU75|uniprotkb:Q5VU76|uniprotkb:Q9BTU3|uniprotkb:Q9UGL2|uniprotkb:Q9UGL3|uniprotkb:Q9UGL5|uniprotkb:B4E0U8|uniprotkb:Q9UGL4|ensembl:ENSP00000355343|ensembl:ENSP00000389445 intact:EBI-713291|uniprotkb:A8K9B8|uniprotkb:Q7Z450|uniprotkb:Q8N6R8|ensembl:ENSP00000350170 psi-mi:ubp2l_human(display_long)|uniprotkb:UBAP2L(gene name)|psi-mi:UBAP2L(display_short)|uniprotkb:Protein NICE-4(gene name synonym)|uniprotkb:KIAA0144(gene name synonym)|uniprotkb:NICE4(gene name synonym) psi-mi:fxr1_human(display_long)|uniprotkb:FXR1(gene name)|psi-mi:FXR1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486538|imex:IM-26985-453 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011508518.1|refseq:NP_001120792.1|refseq:NP_055662.3|refseq:NP_001274744.1|refseq:NP_001274745.1|refseq:XP_005245731.1|refseq:XP_016858467.1|refseq:XP_016858468.1|refseq:XP_016858475.1|refseq:XP_016858476.1|refseq:XP_016858478.1|refseq:XP_016858479.1|ensembl:ENSG00000143569(gene)|ensembl:ENST00000361546(transcript)|ensembl:ENST00000428931(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0031519"(PcG protein complex)|go:"GO:0034063"(stress granule assembly)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR022166|mint:Q14157 refseq:NP_001013456.1|refseq:NP_001013457.1|refseq:NP_005078.2|go:"GO:0007517"(muscle organ development)|ensembl:ENSG00000114416(gene)|ensembl:ENST00000357559(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006915"(apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043034"(costamere)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0060538"(skeletal muscle organ development)|go:"GO:0098793"(presynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2000637"(positive regulation of gene silencing by miRNA)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR032177|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|go:"GO:0014069"(postsynaptic density)|rcsb pdb:2CPQ|rcsb pdb:3KUF|rcsb pdb:3O8V|reactome:R-HSA-6802952|mint:P51114|dip:DIP-40789N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:4iKY4hJOHGSyOOt8zfPhkeyth6Q9606 rogid:pUW5/sakWOiRtZpigPhEMOPJBpk9606 rigid:zLbdK7byEkvtUqOz+2A58LnSbi0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q14157 uniprotkb:P51116 intact:EBI-347762|uniprotkb:Q5VU75|uniprotkb:Q5VU76|uniprotkb:Q9BTU3|uniprotkb:Q9UGL2|uniprotkb:Q9UGL3|uniprotkb:Q9UGL5|uniprotkb:B4E0U8|uniprotkb:Q9UGL4|ensembl:ENSP00000355343|ensembl:ENSP00000389445 intact:EBI-740459|uniprotkb:Q8WUM2|uniprotkb:Q86V09|uniprotkb:B2R9M2|uniprotkb:D3DTQ1|ensembl:ENSP00000250113 psi-mi:ubp2l_human(display_long)|uniprotkb:UBAP2L(gene name)|psi-mi:UBAP2L(display_short)|uniprotkb:Protein NICE-4(gene name synonym)|uniprotkb:KIAA0144(gene name synonym)|uniprotkb:NICE4(gene name synonym) psi-mi:fxr2_human(display_long)|uniprotkb:FXR2(gene name)|psi-mi:FXR2(display_short)|uniprotkb:FMR1L2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486538|imex:IM-26985-453 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:XP_011508518.1|refseq:NP_001120792.1|refseq:NP_055662.3|refseq:NP_001274744.1|refseq:NP_001274745.1|refseq:XP_005245731.1|refseq:XP_016858467.1|refseq:XP_016858468.1|refseq:XP_016858475.1|refseq:XP_016858476.1|refseq:XP_016858478.1|refseq:XP_016858479.1|ensembl:ENSG00000143569(gene)|ensembl:ENST00000361546(transcript)|ensembl:ENST00000428931(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0031519"(PcG protein complex)|go:"GO:0034063"(stress granule assembly)|go:"GO:0061484"(hematopoietic stem cell homeostasis)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR022166|mint:Q14157 interpro:IPR004087(K Homology)|refseq:NP_004851.2|ensembl:ENSG00000129245(gene)|ensembl:ENST00000250113(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0044326"(dendritic spine neck)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051489"(regulation of filopodium assembly)|go:"GO:0098793"(presynapse)|go:"GO:1902737"(dendritic filopodium)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR004088(K Homology, type 1)|interpro:IPR008395(Agenet)|interpro:IPR022034|interpro:IPR032172|interpro:IPR036612|interpro:IPR040148|interpro:IPR040472|interpro:IPR041560|mint:P51116|rcsb pdb:3H8Z - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:4iKY4hJOHGSyOOt8zfPhkeyth6Q9606 rogid:NnYgyzD2NRGIO1ZHukr5qy44qRE9606 rigid:zLbdK7byEkvtUqOz+2A58LnSbi0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15819 uniprotkb:Q32P51 intact:EBI-714329|ensembl:ENSP00000428209 intact:EBI-2556580|uniprotkb:Q5TBS2|ensembl:ENSP00000350090 psi-mi:ub2v2_human(display_long)|uniprotkb:MMS2 homolog(gene name synonym)|uniprotkb:Enterocyte differentiation-associated factor 1(gene name synonym)|uniprotkb:Enterocyte differentiation-promoting factor 1(gene name synonym)|uniprotkb:Vitamin D3-inducible protein(gene name synonym)|uniprotkb:DDVit 1(gene name synonym)|uniprotkb:UBE2V2(gene name)|psi-mi:UBE2V2(display_short)|uniprotkb:MMS2(gene name synonym)|uniprotkb:UEV2(gene name synonym) psi-mi:ra1l2_human(display_long)|uniprotkb:HNRNPA1L(gene name synonym)|uniprotkb:HNRNPA1L2(gene name)|psi-mi:HNRNPA1L2(display_short)|uniprotkb:hnRNP core protein A1-like 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486553|imex:IM-26985-517 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:5AIT|refseq:NP_003341.1|ensembl:ENSG00000169139(gene)|ensembl:ENST00000523111(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042275"(error-free postreplication DNA repair)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q15819|rcsb pdb:1J74|rcsb pdb:1J7D|rcsb pdb:1ZGU|rcsb pdb:3VON|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:7BBF|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-983168|rcsb pdb:7BBD|dip:DIP-29830N refseq:NP_001011724.1|refseq:NP_001011725.1|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0051028"(mRNA transport)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021662|interpro:IPR034803|interpro:IPR035979|mint:Q32P51|go:"GO:0005681"(spliceosomal complex)|ensembl:ENSG00000139675(gene)|ensembl:ENST00000357495(transcript)|go:"GO:0003723"(RNA binding) - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:i4SsftsLfkr72ufUq4QZn571iDQ9606 rogid:Xx00SLimJrf+0e9CrvzUV9PJPcI9606 rigid:gh1lKrDeoW/eEdAWL6uD25Err5w false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15819 uniprotkb:P67809 intact:EBI-714329|ensembl:ENSP00000428209 intact:EBI-354065|uniprotkb:P16990|uniprotkb:P16991|uniprotkb:Q14972|uniprotkb:Q15325|uniprotkb:Q5FVF0|ensembl:ENSP00000361626 psi-mi:ub2v2_human(display_long)|uniprotkb:MMS2 homolog(gene name synonym)|uniprotkb:Enterocyte differentiation-associated factor 1(gene name synonym)|uniprotkb:Enterocyte differentiation-promoting factor 1(gene name synonym)|uniprotkb:Vitamin D3-inducible protein(gene name synonym)|uniprotkb:DDVit 1(gene name synonym)|uniprotkb:UBE2V2(gene name)|psi-mi:UBE2V2(display_short)|uniprotkb:MMS2(gene name synonym)|uniprotkb:UEV2(gene name synonym) psi-mi:ybox1_human(display_long)|uniprotkb:YBX1(gene name)|psi-mi:YBX1(display_short)|uniprotkb:YB1(gene name synonym)|uniprotkb:NSEP1(gene name synonym)|uniprotkb:Y-box transcription factor(gene name synonym)|uniprotkb:CCAAT-binding transcription factor I subunit A(gene name synonym)|uniprotkb:Enhancer factor I subunit A(gene name synonym)|uniprotkb:DNA-binding protein B(gene name synonym)|uniprotkb:Nuclease-sensitive element-binding protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486553|imex:IM-26985-517 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:5AIT|refseq:NP_003341.1|ensembl:ENSG00000169139(gene)|ensembl:ENST00000523111(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042275"(error-free postreplication DNA repair)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q15819|rcsb pdb:1J74|rcsb pdb:1J7D|rcsb pdb:1ZGU|rcsb pdb:3VON|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:7BBF|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-983168|rcsb pdb:7BBD|dip:DIP-29830N refseq:NP_004550.2|dip:DIP-29405N|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990428"(miRNA transport)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P67809|rcsb pdb:1H95|rcsb pdb:5YTS|rcsb pdb:5YTT|rcsb pdb:5YTV|rcsb pdb:5YTX|rcsb pdb:6A6L|rcsb pdb:6KTC|rcsb pdb:6KUG|rcsb pdb:6LMR|rcsb pdb:6LMS|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-9017802|ensembl:ENSG00000065978(gene)|ensembl:ENST00000321358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0008544"(epidermis development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035198"(miRNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050658"(RNA transport)|go:"GO:0051020"(GTPase binding)|go:"GO:0051031"(tRNA transport)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding) - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:i4SsftsLfkr72ufUq4QZn571iDQ9606 rogid:0/mAXOzokPlDByFFzGTP8bp9nqo9606 rigid:gh1lKrDeoW/eEdAWL6uD25Err5w false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15819 uniprotkb:P68363 intact:EBI-714329|ensembl:ENSP00000428209 intact:EBI-487083|intact:EBI-1384226|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:Q27I68|ensembl:ENSP00000336799|uniprotkb:Q8WU19 psi-mi:ub2v2_human(display_long)|uniprotkb:MMS2 homolog(gene name synonym)|uniprotkb:Enterocyte differentiation-associated factor 1(gene name synonym)|uniprotkb:Enterocyte differentiation-promoting factor 1(gene name synonym)|uniprotkb:Vitamin D3-inducible protein(gene name synonym)|uniprotkb:DDVit 1(gene name synonym)|uniprotkb:UBE2V2(gene name)|psi-mi:UBE2V2(display_short)|uniprotkb:MMS2(gene name synonym)|uniprotkb:UEV2(gene name synonym) psi-mi:tba1b_human(display_long)|uniprotkb:TUBA1B(gene name)|psi-mi:TUBA1B(display_short)|uniprotkb:Tubulin alpha-ubiquitous chain(gene name synonym)|uniprotkb:Alpha-tubulin ubiquitous(gene name synonym)|uniprotkb:Tubulin K-alpha-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486553|imex:IM-26985-517 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:5AIT|refseq:NP_003341.1|ensembl:ENSG00000169139(gene)|ensembl:ENST00000523111(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042275"(error-free postreplication DNA repair)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q15819|rcsb pdb:1J74|rcsb pdb:1J7D|rcsb pdb:1ZGU|rcsb pdb:3VON|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:7BBF|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-983168|rcsb pdb:7BBD|dip:DIP-29830N refseq:NP_006073.2|ensembl:ENSG00000123416(gene)|ensembl:ENST00000336023(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-983189|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|go:"GO:0045121"(membrane raft)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68363|rcsb pdb:2E4H|rcsb pdb:5IJ0|rcsb pdb:5IJ9|rcsb pdb:5N5N|rcsb pdb:6E7B|rcsb pdb:6E7C|rcsb pdb:6I2I|go:"GO:0051301"(cell division)|rcsb pdb:6J4V|rcsb pdb:6J8O|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|rcsb pdb:6S8L|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9013407|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-2132295|reactome:R-HSA-9668328 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:i4SsftsLfkr72ufUq4QZn571iDQ9606 rogid:D4YpuLCXl/S+53qV7P7sF81aARY9606 rigid:gh1lKrDeoW/eEdAWL6uD25Err5w false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15819 uniprotkb:Q9Y6H1 intact:EBI-714329|ensembl:ENSP00000428209 intact:EBI-2321769|uniprotkb:Q498C3|uniprotkb:Q6NZ50|ensembl:ENSP00000378812 psi-mi:ub2v2_human(display_long)|uniprotkb:MMS2 homolog(gene name synonym)|uniprotkb:Enterocyte differentiation-associated factor 1(gene name synonym)|uniprotkb:Enterocyte differentiation-promoting factor 1(gene name synonym)|uniprotkb:Vitamin D3-inducible protein(gene name synonym)|uniprotkb:DDVit 1(gene name synonym)|uniprotkb:UBE2V2(gene name)|psi-mi:UBE2V2(display_short)|uniprotkb:MMS2(gene name synonym)|uniprotkb:UEV2(gene name synonym) psi-mi:chch2_human(display_long)|uniprotkb:CHCHD2(gene name)|psi-mi:CHCHD2(display_short)|uniprotkb:C7orf17(gene name synonym)|uniprotkb:HCV NS2 trans-regulated protein(gene name synonym)|uniprotkb:Aging-associated gene 10 protein(gene name synonym)|uniprotkb:AAG10(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486553|imex:IM-26985-517 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) rcsb pdb:5AIT|refseq:NP_003341.1|ensembl:ENSG00000169139(gene)|ensembl:ENST00000523111(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006282"(regulation of DNA repair)|go:"GO:0006301"(postreplication repair)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0031372"(UBC13-MMS2 complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042275"(error-free postreplication DNA repair)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR000608(Ubiquitin-conjugating enzyme, E2)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|mint:Q15819|rcsb pdb:1J74|rcsb pdb:1J7D|rcsb pdb:1ZGU|rcsb pdb:3VON|rcsb pdb:4NR3|rcsb pdb:4NRG|rcsb pdb:4NRI|rcsb pdb:4ONL|rcsb pdb:4ONM|rcsb pdb:4ONN|rcsb pdb:4ORH|rcsb pdb:7BBF|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-5696395|reactome:R-HSA-69473|reactome:R-HSA-8866654|reactome:R-HSA-983168|rcsb pdb:7BBD|dip:DIP-29830N refseq:NP_057223.1|ensembl:ENSG00000106153(gene)|ensembl:ENST00000395422(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900037"(regulation of cellular response to hypoxia)|go:"GO:1905448"(positive regulation of mitochondrial ATP synthesis coupled electron transport)|interpro:IPR010625(CHCH)|mint:Q9Y6H1|reactome:R-HSA-1268020 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:i4SsftsLfkr72ufUq4QZn571iDQ9606 rogid:fdx3lE51+yZ1k3uwh8/LDKJC+CQ9606 rigid:gh1lKrDeoW/eEdAWL6uD25Err5w false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86VY4 uniprotkb:Q9NV06 intact:EBI-3436472|uniprotkb:B3KRF0|uniprotkb:Q9C0B3|ensembl:ENSP00000322802 intact:EBI-7402939|uniprotkb:Q3MII9|uniprotkb:Q96JY7|uniprotkb:Q9NZX3|intact:MINT-4994304|uniprotkb:Q8NCH8|uniprotkb:Q8TC51|ensembl:ENSP00000484962 psi-mi:tsyl5_human(display_long)|uniprotkb:TSPYL5(gene name)|psi-mi:TSPYL5(display_short)|uniprotkb:KIAA1750(gene name synonym) psi-mi:dca13_human(display_long)|uniprotkb:HSPC064(orf name)|uniprotkb:DCAF13(gene name)|psi-mi:DCAF13(display_short)|uniprotkb:WDSOF1(gene name synonym)|uniprotkb:WD repeat and SOF domain-containing protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486370|imex:IM-26985-595 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_277047.2|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0040008"(regulation of growth)|go:"GO:0042393"(histone binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071480"(cellular response to gamma radiation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q86VY4|ensembl:ENSG00000180543(gene)|ensembl:ENST00000322128(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding) refseq:NP_056235.4|ensembl:ENSG00000164934(gene)|ensembl:ENST00000612750(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030054"(cell junction)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR007287(Sof1-like protein)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:Q9NV06|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-8951664 - - comment:mint|comment:homomint|function:Possible role in ribosomal RNA processing|comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Re2EBlbXEybC1/oghH+B067fNDM9606 rogid:Ep2z6/V6/US0sXDqjqjpVqmf/zM9606 rigid:Wc8pTqhAXp+ylu11AGeH1gdmEpI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86VY4 uniprotkb:P49756 intact:EBI-3436472|uniprotkb:B3KRF0|uniprotkb:Q9C0B3|ensembl:ENSP00000322802 intact:EBI-2211856|uniprotkb:Q9UEQ5|uniprotkb:Q9UIE9|uniprotkb:A0PJL9|uniprotkb:B2RNA8|uniprotkb:B3KT03|uniprotkb:Q2TA72|uniprotkb:Q5XJ17|uniprotkb:Q6P665|uniprotkb:Q9H6A1|intact:EBI-2839256|intact:EBI-2859423|ensembl:ENSP00000261973|ensembl:ENSP00000431150 psi-mi:tsyl5_human(display_long)|uniprotkb:TSPYL5(gene name)|psi-mi:TSPYL5(display_short)|uniprotkb:KIAA1750(gene name synonym) psi-mi:rbm25_human(display_long)|uniprotkb:RBM25(gene name)|psi-mi:RBM25(display_short)|uniprotkb:RNPC7(gene name synonym)|uniprotkb:RNA-binding motif protein 25(gene name synonym)|uniprotkb:RNA-binding region-containing protein 7(gene name synonym)|uniprotkb:Protein S164(gene name synonym)|uniprotkb:Arg/Glu/Asp-rich protein of 120 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486370|imex:IM-26985-595 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_277047.2|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0040008"(regulation of growth)|go:"GO:0042393"(histone binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071480"(cellular response to gamma radiation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q86VY4|ensembl:ENSG00000180543(gene)|ensembl:ENST00000322128(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding) refseq:XP_011535346.1|refseq:NP_067062.1|refseq:XP_011535347.1|ensembl:ENSG00000119707(gene)|ensembl:ENST00000261973(transcript)|ensembl:ENST00000527432(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0016607"(nuclear speck)|go:"GO:0042981"(regulation of apoptotic process)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002483(Splicing factor PWI)|interpro:IPR034268|interpro:IPR035979|interpro:IPR036483|mint:P49756|rcsb pdb:3V53|interpro:IPR012677(Nucleotide-binding, alpha-beta plait) - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Re2EBlbXEybC1/oghH+B067fNDM9606 rogid:VRZ6bJro7qw+BXS0rpYZoiD8iAM9606 rigid:Wc8pTqhAXp+ylu11AGeH1gdmEpI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86VY4 uniprotkb:P26196 intact:EBI-3436472|uniprotkb:B3KRF0|uniprotkb:Q9C0B3|ensembl:ENSP00000322802 intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754 psi-mi:tsyl5_human(display_long)|uniprotkb:TSPYL5(gene name)|psi-mi:TSPYL5(display_short)|uniprotkb:KIAA1750(gene name synonym) psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486370|imex:IM-26985-595 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_277047.2|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0040008"(regulation of growth)|go:"GO:0042393"(histone binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071480"(cellular response to gamma radiation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q86VY4|ensembl:ENSG00000180543(gene)|ensembl:ENST00000322128(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding) refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Re2EBlbXEybC1/oghH+B067fNDM9606 rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606 rigid:Wc8pTqhAXp+ylu11AGeH1gdmEpI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86VY4 uniprotkb:Q96JP5 intact:EBI-3436472|uniprotkb:B3KRF0|uniprotkb:Q9C0B3|ensembl:ENSP00000322802 intact:EBI-1052613|uniprotkb:Q86V47|uniprotkb:Q96JP4|uniprotkb:Q96QA3|uniprotkb:A6NHC4|uniprotkb:A8MSG7|ensembl:ENSP00000339030 psi-mi:tsyl5_human(display_long)|uniprotkb:TSPYL5(gene name)|psi-mi:TSPYL5(display_short)|uniprotkb:KIAA1750(gene name synonym) psi-mi:zfp91_human(display_long)|uniprotkb:ZFP91(gene name)|psi-mi:ZFP91(display_short)|uniprotkb:FKSG11(orf name)|uniprotkb:ZNF757(gene name synonym)|uniprotkb:Zinc finger protein 757(gene name synonym)|uniprotkb:Zinc finger protein 91 homolog(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase ZFP91(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486370|imex:IM-26985-595 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_277047.2|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0040008"(regulation of growth)|go:"GO:0042393"(histone binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071480"(cellular response to gamma radiation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q86VY4|ensembl:ENSG00000180543(gene)|ensembl:ENST00000322128(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding) refseq:NP_001183980.1|refseq:NP_444251.1|ensembl:ENSG00000186660(gene)|ensembl:ENST00000316059(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0046872"(metal ion binding)|go:"GO:0070534"(protein K63-linked ubiquitination)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036236|mint:Q96JP5|rcsb pdb:2M9A|go:"GO:0004842"(ubiquitin-protein transferase activity) - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Re2EBlbXEybC1/oghH+B067fNDM9606 rogid:oQuzxnamj/z05P/rG8EXnXTjzz89606 rigid:Wc8pTqhAXp+ylu11AGeH1gdmEpI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86VY4 uniprotkb:O00257 intact:EBI-3436472|uniprotkb:B3KRF0|uniprotkb:Q9C0B3|ensembl:ENSP00000322802 intact:EBI-722425|uniprotkb:Q96C04|uniprotkb:Q6TPI8|uniprotkb:B1PJR7|ensembl:ENSP00000269397 psi-mi:tsyl5_human(display_long)|uniprotkb:TSPYL5(gene name)|psi-mi:TSPYL5(display_short)|uniprotkb:KIAA1750(gene name synonym) psi-mi:cbx4_human(display_long)|uniprotkb:Chromobox protein homolog 4(gene name synonym)|uniprotkb:Polycomb 2 homolog(gene name synonym)|uniprotkb:CBX4(gene name)|psi-mi:CBX4(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486370|imex:IM-26985-595 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_277047.2|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0040008"(regulation of growth)|go:"GO:0042393"(histone binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071480"(cellular response to gamma radiation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q86VY4|ensembl:ENSG00000180543(gene)|ensembl:ENST00000322128(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding) refseq:NP_003646.2|dip:DIP-42042N|ensembl:ENSG00000141582(gene)|ensembl:ENST00000269397(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006325"(chromatin organization)|go:"GO:0016604"(nuclear body)|go:"GO:0016607"(nuclear speck)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032183"(SUMO binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035102"(PRC1 complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061665"(SUMO ligase activity)|interpro:IPR000953(Chromo domain)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR033773|interpro:IPR043531|mint:O00257|rcsb pdb:2K28|rcsb pdb:3I8Z|rcsb pdb:5EPL|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Re2EBlbXEybC1/oghH+B067fNDM9606 rogid:uHX633+6nZPTNHOPmUKK+zW/b4Q9606 rigid:Wc8pTqhAXp+ylu11AGeH1gdmEpI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86VY4 uniprotkb:Q8WWM7 intact:EBI-3436472|uniprotkb:B3KRF0|uniprotkb:Q9C0B3|ensembl:ENSP00000322802 intact:EBI-948363|ensembl:ENSP00000338718|uniprotkb:O95135|uniprotkb:Q6NVJ8|uniprotkb:Q6PJW6|uniprotkb:Q8IU61|uniprotkb:Q8IU95|uniprotkb:Q8WWM3|uniprotkb:Q8WWM4|uniprotkb:Q8WWM5|uniprotkb:Q8WWM6|uniprotkb:Q99703|uniprotkb:B9EGM2|uniprotkb:E9PAR9|uniprotkb:A8K1R6|uniprotkb:Q63ZY4 psi-mi:tsyl5_human(display_long)|uniprotkb:TSPYL5(gene name)|psi-mi:TSPYL5(display_short)|uniprotkb:KIAA1750(gene name synonym) psi-mi:atx2l_human(display_long)|uniprotkb:Ataxin-2 domain protein(gene name synonym)|uniprotkb:Ataxin-2-related protein(gene name synonym)|uniprotkb:ATXN2L(gene name)|psi-mi:ATXN2L(display_short)|uniprotkb:A2D(gene name synonym)|uniprotkb:A2LG(gene name synonym)|uniprotkb:A2LP(gene name synonym)|uniprotkb:A2RP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486370|imex:IM-26985-595 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_277047.2|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0040008"(regulation of growth)|go:"GO:0042393"(histone binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071480"(cellular response to gamma radiation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q86VY4|ensembl:ENSG00000180543(gene)|ensembl:ENST00000322128(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding) ensembl:ENSG00000168488(gene)|ensembl:ENST00000336783(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045296"(cadherin binding)|interpro:IPR009604(Ataxin-2, N-terminal)|interpro:IPR009818(Ataxin-2, C-terminal)|interpro:IPR025852|mint:Q8WWM7|refseq:NP_009176.2|refseq:NP_663760.1|refseq:NP_680780.1|refseq:NP_680781.1|refseq:XP_005255123.1|refseq:NP_059867.3|refseq:NP_680782.1 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Re2EBlbXEybC1/oghH+B067fNDM9606 rogid:t7lrS10IM/5pt+rrbqBRowZ6b+09606 rigid:Wc8pTqhAXp+ylu11AGeH1gdmEpI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86VY4 uniprotkb:P11387 intact:EBI-3436472|uniprotkb:B3KRF0|uniprotkb:Q9C0B3|ensembl:ENSP00000322802 intact:EBI-876302|ensembl:ENSP00000354522|uniprotkb:Q15610|uniprotkb:Q5TFY3|uniprotkb:Q9UJN0|uniprotkb:O43256|uniprotkb:Q12855|uniprotkb:Q12856|uniprotkb:A8KA78|uniprotkb:E1P5W3 psi-mi:tsyl5_human(display_long)|uniprotkb:TSPYL5(gene name)|psi-mi:TSPYL5(display_short)|uniprotkb:KIAA1750(gene name synonym) psi-mi:top1_human(display_long)|uniprotkb:DNA topoisomerase I(gene name synonym)|uniprotkb:TOP1(gene name)|psi-mi:TOP1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486370|imex:IM-26985-595 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_277047.2|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0040008"(regulation of growth)|go:"GO:0042393"(histone binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071480"(cellular response to gamma radiation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q86VY4|ensembl:ENSG00000180543(gene)|ensembl:ENST00000322128(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding) ensembl:ENSG00000198900(gene)|ensembl:ENST00000361337(transcript)|go:"GO:0000932"(P-body)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003917"("DNA topoisomerase type I (single strand cut, ATP-independent) activity")|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006260"(DNA replication)|go:"GO:0006265"(DNA topological change)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007623"(circadian rhythm)|go:"GO:0012501"(programmed cell death)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032922"(circadian regulation of gene expression)|refseq:NP_003277.1|dip:DIP-36356N|go:"GO:0032993"(protein-DNA complex)|go:"GO:0040016"(embryonic cleavage)|go:"GO:0042493"|go:"GO:0043204"(perikaryon)|go:"GO:0097100"(supercoiled DNA binding)|interpro:IPR001631(DNA topoisomerase I, C-terminal)|interpro:IPR008336(DNA topoisomerase I, DNA binding, eukaryotic-type)|interpro:IPR011010(DNA breaking-rejoining enzyme, catalytic core)|interpro:IPR013030(DNA topoisomerase I, DNA binding, mixed alpha/beta motif, eukaryotic-type)|interpro:IPR013034(DNA topoisomerase I, DNA binding, alpha helical motif, eukaryotic-type)|interpro:IPR013499(DNA topoisomerase I, C-terminal, eukaryotic-type)|interpro:IPR013500(DNA topoisomerase I, catalytic core, eukaryotic-type)|interpro:IPR014711(DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type)|interpro:IPR014727(DNA topoisomerase I, catalytic core, alpha/beta subdomain, eukaryotic-type)|interpro:IPR018521|interpro:IPR025834|interpro:IPR036202|mint:P11387|rcsb pdb:1A31|rcsb pdb:1A35|rcsb pdb:1A36|rcsb pdb:1EJ9|rcsb pdb:1K4S|rcsb pdb:1K4T|rcsb pdb:1LPQ|rcsb pdb:1NH3|rcsb pdb:1R49|rcsb pdb:1RR8|rcsb pdb:1RRJ|rcsb pdb:1SC7|rcsb pdb:1SEU|rcsb pdb:1T8I|rcsb pdb:1TL8|reactome:R-HSA-4615885 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Re2EBlbXEybC1/oghH+B067fNDM9606 rogid:kB+3PVybgNp2mtOmDa7x8sygFuU9606 rigid:Wc8pTqhAXp+ylu11AGeH1gdmEpI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86VY4 uniprotkb:Q7L2J0 intact:EBI-3436472|uniprotkb:B3KRF0|uniprotkb:Q9C0B3|ensembl:ENSP00000322802 intact:EBI-2371983|uniprotkb:Q9NPD4|uniprotkb:B3KP86|uniprotkb:D6W5V7|ensembl:ENSP00000308546 psi-mi:tsyl5_human(display_long)|uniprotkb:TSPYL5(gene name)|psi-mi:TSPYL5(display_short)|uniprotkb:KIAA1750(gene name synonym) psi-mi:mepce_human(display_long)|uniprotkb:MEPCE(gene name)|psi-mi:MEPCE(display_short)|uniprotkb:BCDIN3(gene name synonym)|uniprotkb:Bicoid-interacting protein 3 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486370|imex:IM-26985-595 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_277047.2|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0040008"(regulation of growth)|go:"GO:0042393"(histone binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071480"(cellular response to gamma radiation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q86VY4|ensembl:ENSG00000180543(gene)|ensembl:ENST00000322128(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding) refseq:XP_011514712.1|refseq:NP_001181919.1|refseq:NP_001181920.1|refseq:NP_001181921.1|refseq:NP_062552.2|ensembl:ENSG00000146834(gene)|ensembl:ENST00000310512(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001510"(RNA methylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0008171"(O-methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0016073"(snRNA metabolic process)|go:"GO:0017069"(snRNA binding)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0040031"(snRNA modification)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1905382"(positive regulation of snRNA transcription by RNA polymerase II)|go:"GO:1990276"(RNA 5'-methyltransferase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR010675(Bicoid-interacting 3)|interpro:IPR024160|interpro:IPR025714|interpro:IPR029063|interpro:IPR039772|mint:Q7L2J0|rcsb pdb:5UNA|rcsb pdb:6DCB|rcsb pdb:6DCC - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Re2EBlbXEybC1/oghH+B067fNDM9606 rogid:VGhJoO3FD7nsJPVSBsKuKsPJzEM9606 rigid:Wc8pTqhAXp+ylu11AGeH1gdmEpI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86VY4 uniprotkb:P61313 intact:EBI-3436472|uniprotkb:B3KRF0|uniprotkb:Q9C0B3|ensembl:ENSP00000322802 intact:EBI-443462|ensembl:ENSP00000309334|ensembl:ENSP00000346867|ensembl:ENSP00000388529|ensembl:ENSP00000416692|ensembl:ENSP00000483260|ensembl:ENSP00000493759|uniprotkb:Q642I1|uniprotkb:Q9H2E5|uniprotkb:P39030|uniprotkb:P41051|uniprotkb:Q6IPX6|uniprotkb:Q8WYP2|uniprotkb:Q96C44|uniprotkb:Q5U0C0|intact:EBI-2877712 psi-mi:tsyl5_human(display_long)|uniprotkb:TSPYL5(gene name)|psi-mi:TSPYL5(display_short)|uniprotkb:KIAA1750(gene name synonym) psi-mi:rl15_human(display_long)|uniprotkb:RPL15(gene name)|psi-mi:RPL15(display_short)|uniprotkb:EC45(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL15(gene name synonym)|uniprotkb:TCBAP0781(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486370|imex:IM-26985-595 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_277047.2|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0040008"(regulation of growth)|go:"GO:0042393"(histone binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071480"(cellular response to gamma radiation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q86VY4|ensembl:ENSG00000180543(gene)|ensembl:ENST00000322128(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding) ensembl:ENSG00000174748(gene)|ensembl:ENST00000307839(transcript)|ensembl:ENST00000354811(transcript)|ensembl:ENST00000413699(transcript)|ensembl:ENST00000415719(transcript)|ensembl:ENST00000611050(transcript)|ensembl:ENST00000644185(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031672"(A band)|go:"GO:0045296"(cadherin binding)|go:"GO:0045471"(response to ethanol)|interpro:IPR000439(Ribosomal protein L15e)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR020925|interpro:IPR024794|mint:P61313|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_002939.2|refseq:NP_001240308.1|refseq:NP_001240309.1|refseq:NP_001240311.1|refseq:NP_001240312.1|refseq:NP_001240313.1 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Re2EBlbXEybC1/oghH+B067fNDM9606 rogid:wllGpJicgC5uwkZV6e4QRwDcrBo9606 rigid:Wc8pTqhAXp+ylu11AGeH1gdmEpI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86VY4 uniprotkb:Q6UN15 intact:EBI-3436472|uniprotkb:B3KRF0|uniprotkb:Q9C0B3|ensembl:ENSP00000322802 intact:EBI-1021914|uniprotkb:Q0VGE0|uniprotkb:Q499Y4|uniprotkb:Q49AU3|uniprotkb:Q7Z608|uniprotkb:Q8WVN3|uniprotkb:Q96F80|uniprotkb:Q9H077|intact:EBI-11535474|ensembl:ENSP00000336752|uniprotkb:B4DIR3|uniprotkb:G3XAD6 psi-mi:tsyl5_human(display_long)|uniprotkb:TSPYL5(gene name)|psi-mi:TSPYL5(display_short)|uniprotkb:KIAA1750(gene name synonym) psi-mi:fip1_human(display_long)|uniprotkb:Factor interacting with PAP(gene name synonym)|uniprotkb:FIP1-like 1 protein(gene name synonym)|uniprotkb:Rearranged in hypereosinophilia(gene name synonym)|uniprotkb:FIP1L1(gene name)|psi-mi:FIP1L1(display_short)|uniprotkb:FIP1(gene name synonym)|uniprotkb:RHE(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486370|imex:IM-26985-595 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_277047.2|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0040008"(regulation of growth)|go:"GO:0042393"(histone binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071480"(cellular response to gamma radiation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q86VY4|ensembl:ENSG00000180543(gene)|ensembl:ENST00000322128(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding) ensembl:ENST00000306932|ensembl:ENSP00000302993|ensembl:ENSP00000336752|ensembl:ENST00000358575|ensembl:ENSP00000351383|ensembl:ENST00000507922|ensembl:ENSP00000425456|refseq:NP_001128409.1|refseq:NP_001128410.1|refseq:NP_112179.2|ensembl:ENSG00000145216(gene)|ensembl:ENST00000337488(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005847"(mRNA cleavage and polyadenylation specificity factor complex)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0098789"(pre-mRNA cleavage required for polyadenylation)|interpro:IPR007854(Fip1)|mint:Q6UN15|rcsb pdb:7K95|reactome:R-HSA-159231|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|reactome:R-HSA-77595|reactome:R-HSA-9673766|dip:DIP-42503N - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Re2EBlbXEybC1/oghH+B067fNDM9606 rogid:41uK1l8RV99q4k4Z7K9zeG3TJHA9606 rigid:Wc8pTqhAXp+ylu11AGeH1gdmEpI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86VY4 uniprotkb:O75400 intact:EBI-3436472|uniprotkb:B3KRF0|uniprotkb:Q9C0B3|ensembl:ENSP00000322802 intact:EBI-473291|uniprotkb:O43856|uniprotkb:O75404|uniprotkb:Q8TBQ1|uniprotkb:Q9H782|uniprotkb:Q9NWU9|uniprotkb:Q9P0Q2|uniprotkb:Q9Y5A8 psi-mi:tsyl5_human(display_long)|uniprotkb:TSPYL5(gene name)|psi-mi:TSPYL5(display_short)|uniprotkb:KIAA1750(gene name synonym) psi-mi:pr40a_human(display_long)|uniprotkb:Formin-binding protein 3(gene name synonym)|uniprotkb:Formin-binding protein 11(gene name synonym)|uniprotkb:Huntingtin-interacting protein A(gene name synonym)|uniprotkb:Huntingtin yeast partner A(gene name synonym)|uniprotkb:Fas ligand-associated factor 1(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-6(gene name synonym)|uniprotkb:HSPC225(orf name)|uniprotkb:PRPF40A(gene name)|psi-mi:PRPF40A(display_short)|uniprotkb:FLAF1(gene name synonym)|uniprotkb:HYPA(gene name synonym)|uniprotkb:FBP11(gene name synonym)|uniprotkb:FNBP3(gene name synonym)|uniprotkb:HIP10(gene name synonym)|uniprotkb:Huntingtin-interacting protein 10(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486370|imex:IM-26985-595 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_277047.2|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0040008"(regulation of growth)|go:"GO:0042393"(histone binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071480"(cellular response to gamma radiation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q86VY4|ensembl:ENSG00000180543(gene)|ensembl:ENST00000322128(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding) go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005685"(U1 snRNP)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016477"(cell migration)|go:"GO:0016607"(nuclear speck)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0045292"(mRNA cis splicing, via spliceosome)|go:"GO:0051301"(cell division)|go:"GO:0071004"(U2-type prespliceosome)|rcsb pdb:1UZC|rcsb pdb:1YWI|rcsb pdb:1YWJ|rcsb pdb:1ZR7|rcsb pdb:2CQN|rcsb pdb:2DYF|rcsb pdb:2KZG|rcsb pdb:2L5F|rcsb pdb:2L9V|rcsb pdb:2LKS|reactome:R-HSA-72163|refseq:NP_060362.3|interpro:IPR002713(FF)|interpro:IPR001202(WW/Rsp5/WWP)|mint:O75400|interpro:IPR036020|interpro:IPR036517|interpro:IPR039726 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Re2EBlbXEybC1/oghH+B067fNDM9606 rogid:XgnBshjHK5u08HROtUS9Zr2Ot809606 rigid:Wc8pTqhAXp+ylu11AGeH1gdmEpI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86VY4 uniprotkb:P23246 intact:EBI-3436472|uniprotkb:B3KRF0|uniprotkb:Q9C0B3|ensembl:ENSP00000322802 intact:EBI-355453|uniprotkb:P30808|uniprotkb:Q5SZ71|ensembl:ENSP00000349748 psi-mi:tsyl5_human(display_long)|uniprotkb:TSPYL5(gene name)|psi-mi:TSPYL5(display_short)|uniprotkb:KIAA1750(gene name synonym) psi-mi:sfpq_human(display_long)|uniprotkb:SFPQ(gene name)|psi-mi:SFPQ(display_short)|uniprotkb:PSF(gene name synonym)|uniprotkb:Polypyrimidine tract-binding protein-associated-splicing factor(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 100 kDa subunit(gene name synonym)|uniprotkb:100 kDa DNA-pairing protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486370|imex:IM-26985-595 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_277047.2|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0040008"(regulation of growth)|go:"GO:0042393"(histone binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071480"(cellular response to gamma radiation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q86VY4|ensembl:ENSG00000180543(gene)|ensembl:ENST00000322128(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding) refseq:NP_005057.1|ensembl:ENSG00000116560(gene)|ensembl:ENST00000357214(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0003723"(RNA binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0042382"(paraspeckles)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042754"(negative regulation of circadian rhythm)|go:"GO:0005634"(nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045876"(positive regulation of sister chromatid cohesion)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0048511"(rhythmic process)|go:"GO:0070932"(histone H3 deacetylation)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0098963"(dendritic transport of messenger ribonucleoprotein complex)|go:"GO:1902177"(positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:0006355"(regulation of transcription, DNA-templated)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034525|interpro:IPR034526|interpro:IPR035979|mint:P23246|rcsb pdb:4WII|rcsb pdb:4WIJ|rcsb pdb:4WIK|rcsb pdb:5WPA|rcsb pdb:6NCQ|rcsb pdb:6OWJ|rcsb pdb:6WMZ|rcsb pdb:7LRQ|rcsb pdb:7LRU|reactome:R-HSA-8849468|reactome:R-HSA-9635465|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|refseq:XP_005271169.1|refseq:XP_005271170.1|refseq:XP_005271172.1|refseq:XP_016857542.1|refseq:XP_016857543.1|dip:DIP-31272N - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Re2EBlbXEybC1/oghH+B067fNDM9606 rogid:B7mSc6tthLbSHo0qz0SMZBSl3HA9606 rigid:Wc8pTqhAXp+ylu11AGeH1gdmEpI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86VY4 uniprotkb:P68363 intact:EBI-3436472|uniprotkb:B3KRF0|uniprotkb:Q9C0B3|ensembl:ENSP00000322802 intact:EBI-487083|intact:EBI-1384226|uniprotkb:P04687|uniprotkb:P05209|uniprotkb:Q27I68|ensembl:ENSP00000336799|uniprotkb:Q8WU19 psi-mi:tsyl5_human(display_long)|uniprotkb:TSPYL5(gene name)|psi-mi:TSPYL5(display_short)|uniprotkb:KIAA1750(gene name synonym) psi-mi:tba1b_human(display_long)|uniprotkb:TUBA1B(gene name)|psi-mi:TUBA1B(display_short)|uniprotkb:Tubulin alpha-ubiquitous chain(gene name synonym)|uniprotkb:Alpha-tubulin ubiquitous(gene name synonym)|uniprotkb:Tubulin K-alpha-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486370|imex:IM-26985-595 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_277047.2|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0040008"(regulation of growth)|go:"GO:0042393"(histone binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071480"(cellular response to gamma radiation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q86VY4|ensembl:ENSG00000180543(gene)|ensembl:ENST00000322128(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding) refseq:NP_006073.2|ensembl:ENSG00000123416(gene)|ensembl:ENST00000336023(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0007017"(microtubule-based process)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031625"(ubiquitin protein ligase binding)|reactome:R-HSA-983189|go:"GO:0071353"(cellular response to interleukin-4)|interpro:IPR000217(Tubulin)|go:"GO:0045121"(membrane raft)|interpro:IPR002452(Alpha tubulin)|interpro:IPR003008(Tubulin/FtsZ, GTPase)|interpro:IPR008280(Tubulin/FtsZ, C-terminal)|interpro:IPR017975|interpro:IPR018316|interpro:IPR023123|interpro:IPR036525|interpro:IPR037103|mint:P68363|rcsb pdb:2E4H|rcsb pdb:5IJ0|rcsb pdb:5IJ9|rcsb pdb:5N5N|rcsb pdb:6E7B|rcsb pdb:6E7C|rcsb pdb:6I2I|go:"GO:0051301"(cell division)|rcsb pdb:6J4V|rcsb pdb:6J8O|rcsb pdb:6QUS|rcsb pdb:6QUY|rcsb pdb:6QVE|rcsb pdb:6QVJ|rcsb pdb:6S8L|reactome:R-HSA-1445148|reactome:R-HSA-190840|reactome:R-HSA-190861|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-380320|reactome:R-HSA-389960|reactome:R-HSA-389977|reactome:R-HSA-437239|reactome:R-HSA-5610787|reactome:R-HSA-5617833|reactome:R-HSA-5620924|reactome:R-HSA-5626467|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8955332|reactome:R-HSA-9013407|reactome:R-HSA-9609690|reactome:R-HSA-9609736|reactome:R-HSA-9619483|reactome:R-HSA-9646399|reactome:R-HSA-9648025|reactome:R-HSA-2132295|reactome:R-HSA-9668328 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Re2EBlbXEybC1/oghH+B067fNDM9606 rogid:D4YpuLCXl/S+53qV7P7sF81aARY9606 rigid:Wc8pTqhAXp+ylu11AGeH1gdmEpI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86VY4 uniprotkb:P39019 intact:EBI-3436472|uniprotkb:B3KRF0|uniprotkb:Q9C0B3|ensembl:ENSP00000322802 intact:EBI-354451|ensembl:ENSP00000469228|ensembl:ENSP00000470004|ensembl:ENSP00000470972 psi-mi:tsyl5_human(display_long)|uniprotkb:TSPYL5(gene name)|psi-mi:TSPYL5(display_short)|uniprotkb:KIAA1750(gene name synonym) psi-mi:rs19_human(display_long)|uniprotkb:RPS19(gene name)|psi-mi:RPS19(display_short)|uniprotkb:Small ribosomal subunit protein eS19(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486370|imex:IM-26985-595 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_277047.2|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0040008"(regulation of growth)|go:"GO:0042393"(histone binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071480"(cellular response to gamma radiation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q86VY4|ensembl:ENSG00000180543(gene)|ensembl:ENST00000322128(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding) refseq:NP_001013.1|ensembl:ENSG00000105372(gene)|ensembl:ENST00000593863(transcript)|ensembl:ENST00000598742(transcript)|go:"GO:0000028"(ribosomal small subunit assembly)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0003723"(RNA binding)|ensembl:ENST00000600467(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0007000"(nucleolus organization)|go:"GO:0009991"(response to extracellular stimulus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030218"(erythrocyte differentiation)|go:"GO:0030490"(maturation of SSU-rRNA)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0060265"(positive regulation of respiratory burst involved in inflammatory response)|go:"GO:0060266"(negative regulation of respiratory burst involved in inflammatory response)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001266(Ribosomal protein S19e)|interpro:IPR018277|interpro:IPR036388|interpro:IPR036390|mint:P39019|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001308412.1|refseq:NP_001308413.1 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Re2EBlbXEybC1/oghH+B067fNDM9606 rogid:3YqdJJJG+2nqoBf3PLu1fs7pVkY9606 rigid:Wc8pTqhAXp+ylu11AGeH1gdmEpI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86VY4 uniprotkb:P62899 intact:EBI-3436472|uniprotkb:B3KRF0|uniprotkb:Q9C0B3|ensembl:ENSP00000322802 intact:EBI-1053664|intact:EBI-3867511|uniprotkb:B7Z4K2|uniprotkb:P12947|uniprotkb:Q53SQ5|uniprotkb:Q6LBJ6|uniprotkb:D3DVJ4|uniprotkb:Q6IRZ0|ensembl:ENSP00000264258|ensembl:ENSP00000386681 psi-mi:tsyl5_human(display_long)|uniprotkb:TSPYL5(gene name)|psi-mi:TSPYL5(display_short)|uniprotkb:KIAA1750(gene name synonym) psi-mi:rl31_human(display_long)|uniprotkb:RPL31(gene name)|psi-mi:RPL31(display_short)|uniprotkb:Large ribosomal subunit protein eL31(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486370|imex:IM-26985-595 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_277047.2|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0040008"(regulation of growth)|go:"GO:0042393"(histone binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071480"(cellular response to gamma radiation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q86VY4|ensembl:ENSG00000180543(gene)|ensembl:ENST00000322128(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding) refseq:NP_000984.1|refseq:NP_001092047.1|refseq:NP_001093163.1|ensembl:ENSG00000071082(gene)|ensembl:ENST00000264258(transcript)|ensembl:ENST00000409733(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000054(Ribosomal protein L31e)|interpro:IPR020052|interpro:IPR023621|mint:P62899|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Re2EBlbXEybC1/oghH+B067fNDM9606 rogid:77LFR7/2somk6blVogZf1XFdJLk9606 rigid:Wc8pTqhAXp+ylu11AGeH1gdmEpI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86VY4 uniprotkb:Q5HYJ3 intact:EBI-3436472|uniprotkb:B3KRF0|uniprotkb:Q9C0B3|ensembl:ENSP00000322802 intact:EBI-751192|uniprotkb:Q6PIU3|uniprotkb:Q8TC53|uniprotkb:B2R9C2|ensembl:ENSP00000351631 psi-mi:tsyl5_human(display_long)|uniprotkb:TSPYL5(gene name)|psi-mi:TSPYL5(display_short)|uniprotkb:KIAA1750(gene name synonym) psi-mi:fa76b_human(display_long)|uniprotkb:FAM76B(gene name)|psi-mi:FAM76B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486370|imex:IM-26985-595 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_277047.2|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0040008"(regulation of growth)|go:"GO:0042393"(histone binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071480"(cellular response to gamma radiation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q86VY4|ensembl:ENSG00000180543(gene)|ensembl:ENST00000322128(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding) refseq:NP_653265.3|ensembl:ENSG00000077458(gene)|ensembl:ENST00000358780(transcript)|go:"GO:0016607"(nuclear speck)|interpro:IPR029661|interpro:IPR032017|mint:Q5HYJ3 - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Re2EBlbXEybC1/oghH+B067fNDM9606 rogid:FWmHMXjKuPdNvpa793hQ1F+Tb909606 rigid:Wc8pTqhAXp+ylu11AGeH1gdmEpI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86VY4 uniprotkb:Q7Z417 intact:EBI-3436472|uniprotkb:B3KRF0|uniprotkb:Q9C0B3|ensembl:ENSP00000322802 intact:EBI-1210753|intact:EBI-10172018|uniprotkb:A1L3A7|uniprotkb:Q9P2M5|uniprotkb:A1L3A6|ensembl:ENSP00000225388 psi-mi:tsyl5_human(display_long)|uniprotkb:TSPYL5(gene name)|psi-mi:TSPYL5(display_short)|uniprotkb:KIAA1750(gene name synonym) psi-mi:nufp2_human(display_long)|uniprotkb:NUFIP2(gene name)|psi-mi:NUFIP2(display_short)|uniprotkb:KIAA1321(gene name synonym)|uniprotkb:PIG1(orf name)|uniprotkb:FMRP-interacting protein 2(gene name synonym)|uniprotkb:82 kDa FMRP-interacting protein(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 1 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486370|imex:IM-26985-595 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_277047.2|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0040008"(regulation of growth)|go:"GO:0042393"(histone binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071480"(cellular response to gamma radiation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q86VY4|ensembl:ENSG00000180543(gene)|ensembl:ENST00000322128(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding) refseq:NP_065823.1|dip:DIP-29023N|ensembl:ENSG00000108256(gene)|ensembl:ENST00000225388(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR032747|mint:Q7Z417 - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Re2EBlbXEybC1/oghH+B067fNDM9606 rogid:zdbkRisveP+8g70umfbEPHTnAgk9606 rigid:Wc8pTqhAXp+ylu11AGeH1gdmEpI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86VY4 uniprotkb:P62805 intact:EBI-3436472|uniprotkb:B3KRF0|uniprotkb:Q9C0B3|ensembl:ENSP00000322802 intact:EBI-302023|ensembl:ENSP00000244537|ensembl:ENSP00000347168|ensembl:ENSP00000350767|ensembl:ENSP00000366974|ensembl:ENSP00000366956|ensembl:ENSP00000462667|ensembl:ENSP00000367034|ensembl:ENSP00000478519|ensembl:ENSP00000478786|ensembl:ENSP00000443017|ensembl:ENSP00000462355|ensembl:ENSP00000479106|ensembl:ENSP00000479461|uniprotkb:A2VCL0|uniprotkb:P02304|uniprotkb:P02305|uniprotkb:Q6DRA9|uniprotkb:Q6FGB8|uniprotkb:Q6NWP7|ensembl:ENSP00000479794|ensembl:ENSP00000480960|ensembl:ENSP00000481343|ensembl:ENSP00000481486|ensembl:ENSP00000481507|ensembl:ENSP00000482412|ensembl:ENSP00000484789|ensembl:ENSP00000489319|ensembl:ENSP00000489567 psi-mi:tsyl5_human(display_long)|uniprotkb:TSPYL5(gene name)|psi-mi:TSPYL5(display_short)|uniprotkb:KIAA1750(gene name synonym) psi-mi:h4_human(display_long)|uniprotkb:H4-16(gene name)|psi-mi:H4-16(display_short)|uniprotkb:H4C1(gene name)|psi-mi:H4C1(display_short)|uniprotkb:H4C11(gene name)|psi-mi:H4C11(display_short)|uniprotkb:H4C12(gene name)|psi-mi:H4C12(display_short)|uniprotkb:H4C13(gene name)|psi-mi:H4C13(display_short)|uniprotkb:H4C14(gene name)|psi-mi:H4C14(display_short)|uniprotkb:H4C15(gene name)|psi-mi:H4C15(display_short)|uniprotkb:H4C2(gene name)|psi-mi:H4C2(display_short)|uniprotkb:H4C3(gene name)|psi-mi:H4C3(display_short)|uniprotkb:H4C4(gene name)|psi-mi:H4C4(display_short)|uniprotkb:H4C5(gene name)|psi-mi:H4C5(display_short)|uniprotkb:H4C6(gene name)|psi-mi:H4C6(display_short)|uniprotkb:H4C8(gene name)|psi-mi:H4C8(display_short)|uniprotkb:H4C9(gene name)|psi-mi:H4C9(display_short)|uniprotkb:H4/A(gene name synonym)|uniprotkb:H4/B(gene name synonym)|uniprotkb:H4/C(gene name synonym)|uniprotkb:H4/D(gene name synonym)|uniprotkb:H4/E(gene name synonym)|uniprotkb:H4/G(gene name synonym)|uniprotkb:H4/H(gene name synonym)|uniprotkb:H4/I(gene name synonym)|uniprotkb:H4/J(gene name synonym)|uniprotkb:H4/K(gene name synonym)|uniprotkb:H4/M(gene name synonym)|uniprotkb:H4/N(gene name synonym)|uniprotkb:H4/O(gene name synonym)|uniprotkb:H4F2(gene name synonym)|uniprotkb:H4FA(gene name synonym)|uniprotkb:H4FB(gene name synonym)|uniprotkb:H4FC(gene name synonym)|uniprotkb:H4FD(gene name synonym)|uniprotkb:H4FE(gene name synonym)|uniprotkb:H4FG(gene name synonym)|uniprotkb:H4FH(gene name synonym)|uniprotkb:H4FI(gene name synonym)|uniprotkb:H4FJ(gene name synonym)|uniprotkb:H4FK(gene name synonym)|uniprotkb:H4FM(gene name synonym)|uniprotkb:H4FN(gene name synonym)|uniprotkb:H4FO(gene name synonym)|uniprotkb:HIST1H4A(gene name synonym)|uniprotkb:HIST1H4B(gene name synonym)|uniprotkb:HIST1H4C(gene name synonym)|uniprotkb:HIST1H4D(gene name synonym)|uniprotkb:HIST1H4E(gene name synonym)|uniprotkb:HIST1H4F(gene name synonym)|uniprotkb:HIST1H4H(gene name synonym)|uniprotkb:HIST1H4I(gene name synonym)|uniprotkb:HIST1H4J(gene name synonym)|uniprotkb:HIST1H4K(gene name synonym)|uniprotkb:HIST1H4L(gene name synonym)|uniprotkb:HIST2H4(gene name synonym)|uniprotkb:HIST2H4A(gene name synonym)|uniprotkb:HIST2H4B(gene name synonym)|uniprotkb:HIST4H4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486370|imex:IM-26985-595 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_277047.2|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0040008"(regulation of growth)|go:"GO:0042393"(histone binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071480"(cellular response to gamma radiation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q86VY4|ensembl:ENSG00000180543(gene)|ensembl:ENST00000322128(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding) ensembl:ENSG00000197061(gene)|ensembl:ENSG00000276180(gene)|ensembl:ENSG00000197238(gene)|ensembl:ENSG00000276966(gene)|ensembl:ENSG00000277157(gene)|ensembl:ENSG00000270276(gene)|ensembl:ENSG00000197837(gene)|ensembl:ENSG00000270882(gene)|ensembl:ENSG00000278637(gene)|ensembl:ENSG00000273542(gene)|ensembl:ENSG00000274618(gene)|ensembl:ENSG00000278705(gene)|ensembl:ENSG00000275126(gene)|ensembl:ENSG00000158406(gene)|dip:DIP-33079N|ensembl:ENST00000244537(transcript)|ensembl:ENST00000355057(transcript)|ensembl:ENST00000358064(transcript)|ensembl:ENST00000377727(transcript)|ensembl:ENST00000377745(transcript)|ensembl:ENST00000377803(transcript)|ensembl:ENST00000539745(transcript)|ensembl:ENST00000578186(transcript)|ensembl:ENST00000579512(transcript)|ensembl:ENST00000611927(transcript)|ensembl:ENST00000612061(transcript)|ensembl:ENST00000613412(transcript)|ensembl:ENST00000614247(transcript)|ensembl:ENST00000614272(transcript)|ensembl:ENST00000615164(transcript)|ensembl:ENST00000615353(transcript)|ensembl:ENST00000617569(transcript)|ensembl:ENST00000618193(transcript)|ensembl:ENST00000618305(transcript)|ensembl:ENST00000621520(transcript)|ensembl:ENST00000634560(transcript)|ensembl:ENST00000634956(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0005576"(extracellular region)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001951(Histone H4)|interpro:IPR004823("TATA box binding protein associated factor (TAF)")|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AYW|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3CFS|rcsb pdb:3CFV|rcsb pdb:3F9W|rcsb pdb:3F9X|rcsb pdb:3F9Y|rcsb pdb:3F9Z|rcsb pdb:3IJ1|rcsb pdb:3JPX|rcsb pdb:3NQJ|rcsb pdb:3NQU|rcsb pdb:3O36|rcsb pdb:3QBY|rcsb pdb:3QZS|rcsb pdb:3QZT|rcsb pdb:3QZV|rcsb pdb:3R45|rcsb pdb:3UVW|rcsb pdb:3UVX|rcsb pdb:3UVY|rcsb pdb:3UW9|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WA9|rcsb pdb:3WAA|rcsb pdb:3WKJ|rcsb pdb:3WTP|rcsb pdb:3X1S|rcsb pdb:3X1T|rcsb pdb:3X1U|rcsb pdb:3X1V|rcsb pdb:4GQB|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4M38|rcsb pdb:4N3W|rcsb pdb:4N4F|rcsb pdb:4QUT|rcsb pdb:4QUU|rcsb pdb:4QYD|rcsb pdb:4U9W|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4YY6|rcsb pdb:4YYD|rcsb pdb:4YYG|rcsb pdb:4YYH|rcsb pdb:4YYI|rcsb pdb:4YYJ|rcsb pdb:4YYK|rcsb pdb:4YYM|rcsb pdb:4YYN|rcsb pdb:4Z2M|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5CPI|interpro:IPR019809|interpro:IPR035425|mint:P62805|rcsb pdb:1ZKK|rcsb pdb:2BQZ|rcsb pdb:2CV5|rcsb pdb:2IG0|rcsb pdb:2KWN|rcsb pdb:2KWO|rcsb pdb:2LVM|rcsb pdb:2QQS|rcsb pdb:2RJE|rcsb pdb:2RNY|interpro:IPR009072(Histone-fold)|rcsb pdb:2RS9|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:5GT3|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JA4|rcsb pdb:5JRG|rcsb pdb:5KDM|rcsb pdb:5TEG|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5YE3|rcsb pdb:5YE4|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:5ZGC|rcsb pdb:5CPJ|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:5CPK|rcsb pdb:6A5P|rcsb pdb:5FA5|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6ACP|rcsb pdb:6BUZ|rcsb pdb:6C0W|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6FML|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KE9|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9H|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LE9|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6M4D|rcsb pdb:5FFW|rcsb pdb:5FWE|rcsb pdb:5GSE|rcsb pdb:5GSU|rcsb pdb:5GT0|rcsb pdb:6M4G|rcsb pdb:6M4H|rcsb pdb:6MLC|rcsb pdb:6MUO|rcsb pdb:6MUP|rcsb pdb:6O1D|rcsb pdb:6R0C|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|refseq:NP_001029249.1|refseq:NP_003486.1|refseq:NP_003529.1|refseq:NP_003530.1|refseq:NP_003531.1|refseq:NP_003532.1|refseq:NP_003533.1|refseq:NP_003534.1|refseq:NP_003535.1|refseq:NP_003536.1|refseq:NP_003537.1|refseq:NP_003539.1|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6RNY|rcsb pdb:6RXS|rcsb pdb:6SE0|rcsb pdb:6SE6|rcsb pdb:6SEE|rcsb pdb:6SEF|rcsb pdb:6SEG|rcsb pdb:6T79|rcsb pdb:6T7A|rcsb pdb:6T7B|rcsb pdb:6T7C|rcsb pdb:6T7D|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6UPK|rcsb pdb:6UPL|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6V92|rcsb pdb:6VO5|rcsb pdb:6X59|rcsb pdb:6X5A|rcsb pdb:6XJD|rcsb pdb:6Y5D|rcsb pdb:6YOV|rcsb pdb:7A08|rcsb pdb:7BWD|rcsb pdb:7BXT|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7CIZ|rcsb pdb:7CJ0|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7DBP|rcsb pdb:7JO9|rcsb pdb:7JOA|rcsb pdb:7JZV|rcsb pdb:7K5X|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LMK|rcsb pdb:7LMM|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214841|reactome:R-HSA-3214842|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-4551638|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|refseq:NP_068803.1|refseq:NP_778224.1|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Re2EBlbXEybC1/oghH+B067fNDM9606 rogid:LZSfhrpw0PcDREEoJ1UMkBvnUfA9606 rigid:Wc8pTqhAXp+ylu11AGeH1gdmEpI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86VY4 uniprotkb:P62917 intact:EBI-3436472|uniprotkb:B3KRF0|uniprotkb:Q9C0B3|ensembl:ENSP00000322802 intact:EBI-438527|ensembl:ENSP00000262584|ensembl:ENSP00000378378|ensembl:ENSP00000433464|uniprotkb:P25120|uniprotkb:Q567Q7|uniprotkb:Q969V7|uniprotkb:Q9BWQ9|uniprotkb:A8K094|uniprotkb:D3DWN2 psi-mi:tsyl5_human(display_long)|uniprotkb:TSPYL5(gene name)|psi-mi:TSPYL5(display_short)|uniprotkb:KIAA1750(gene name synonym) psi-mi:rl8_human(display_long)|uniprotkb:RPL8(gene name)|psi-mi:RPL8(display_short)|uniprotkb:Large ribosomal subunit protein uL2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486370|imex:IM-26985-595 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_277047.2|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0040008"(regulation of growth)|go:"GO:0042393"(histone binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071480"(cellular response to gamma radiation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q86VY4|ensembl:ENSG00000180543(gene)|ensembl:ENST00000322128(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding) rcsb pdb:4CCN|rcsb pdb:4CCO|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:4Y3O|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000161016(gene)|ensembl:ENST00000262584(transcript)|ensembl:ENST00000394920(transcript)|ensembl:ENST00000528957(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0098794"(postsynapse)|interpro:IPR002171(Ribosomal protein L2)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR014726(Ribosomal protein L2, domain 3)|interpro:IPR022666|interpro:IPR022669|interpro:IPR022671|interpro:IPR023672|mint:P62917|rcsb pdb:4CCM|refseq:NP_000964.1|refseq:NP_150644.1|refseq:NP_001304700.1|refseq:NP_001304711.1|dip:DIP-37967N - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Re2EBlbXEybC1/oghH+B067fNDM9606 rogid:+b/ORzdCy/nqFLsKRV9VhIZgdjg9606 rigid:Wc8pTqhAXp+ylu11AGeH1gdmEpI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86VY4 uniprotkb:Q15233 intact:EBI-3436472|uniprotkb:B3KRF0|uniprotkb:Q9C0B3|ensembl:ENSP00000322802 intact:EBI-350527|ensembl:ENSP00000503233|uniprotkb:O00201|uniprotkb:P30807|uniprotkb:Q12786|uniprotkb:Q9BQC5|ensembl:ENSP00000276079|ensembl:ENSP00000362947|ensembl:ENSP00000406673|ensembl:ENSP00000410299|ensembl:ENSP00000415777|ensembl:ENSP00000503031|ensembl:ENSP00000504314|ensembl:ENSP00000504351|uniprotkb:D3DVV4|uniprotkb:B7Z4C2|uniprotkb:F5GYZ3 psi-mi:tsyl5_human(display_long)|uniprotkb:TSPYL5(gene name)|psi-mi:TSPYL5(display_short)|uniprotkb:KIAA1750(gene name synonym) psi-mi:nono_human(display_long)|uniprotkb:NONO(gene name)|psi-mi:NONO(display_short)|uniprotkb:NRB54(gene name synonym)|uniprotkb:54 kDa nuclear RNA- and DNA-binding protein(gene name synonym)|uniprotkb:"p54(nrb)"(gene name synonym)|uniprotkb:55 kDa nuclear protein(gene name synonym)|uniprotkb:NMT55(gene name synonym)|uniprotkb:DNA-binding p52/p100 complex, 52 kDa subunit(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486370|imex:IM-26985-595 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_277047.2|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0040008"(regulation of growth)|go:"GO:0042393"(histone binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071480"(cellular response to gamma radiation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q86VY4|ensembl:ENSG00000180543(gene)|ensembl:ENST00000322128(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding) refseq:NP_001138880.1|refseq:NP_001138881.1|refseq:NP_001138882.1|refseq:NP_031389.3|ensembl:ENSG00000147140(gene)|ensembl:ENST00000276079(transcript)|ensembl:ENST00000373841(transcript)|ensembl:ENST00000420903(transcript)|ensembl:ENST00000450092(transcript)|ensembl:ENST00000454976(transcript)|ensembl:ENST00000677274(transcript)|ensembl:ENST00000677446(transcript)|ensembl:ENST00000677612(transcript)|ensembl:ENST00000678231(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001650"(fibrillar center)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0007623"(circadian rhythm)|go:"GO:0008380"(RNA splicing)|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0042382"(paraspeckles)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012975(NOPS)|interpro:IPR034552|interpro:IPR035979|mint:Q15233|rcsb pdb:3SDE|rcsb pdb:5IFM|rcsb pdb:6WMZ|rcsb pdb:7LRQ|dip:DIP-29951N - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Re2EBlbXEybC1/oghH+B067fNDM9606 rogid:5W3ooO4h0qh3GKO+WjDrLBhihHA9606 rigid:Wc8pTqhAXp+ylu11AGeH1gdmEpI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86VY4 uniprotkb:Q13610 intact:EBI-3436472|uniprotkb:B3KRF0|uniprotkb:Q9C0B3|ensembl:ENSP00000322802 intact:EBI-1050630|uniprotkb:A8K3R6|ensembl:ENSP00000387365|uniprotkb:Q7Z3X9 psi-mi:tsyl5_human(display_long)|uniprotkb:TSPYL5(gene name)|psi-mi:TSPYL5(display_short)|uniprotkb:KIAA1750(gene name synonym) psi-mi:pwp1_human(display_long)|uniprotkb:Keratinocyte protein IEF SSP 9502(gene name synonym)|uniprotkb:PWP1(gene name)|psi-mi:PWP1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486370|imex:IM-26985-595 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_277047.2|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0040008"(regulation of growth)|go:"GO:0042393"(histone binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071480"(cellular response to gamma radiation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q86VY4|ensembl:ENSG00000180543(gene)|ensembl:ENST00000322128(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding) refseq:NP_008993.1|refseq:NP_001304892.1|ensembl:ENSG00000136045(gene)|ensembl:ENST00000412830(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006364"(rRNA processing)|go:"GO:0033140"(negative regulation of peptidyl-serine phosphorylation of STAT protein)|go:"GO:0034773"(histone H4-K20 trimethylation)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1990889"(H4K20me3 modified histone binding)|go:"GO:2000738"(positive regulation of stem cell differentiation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|interpro:IPR044285|mint:Q13610 - - comment:"author score: 29" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Re2EBlbXEybC1/oghH+B067fNDM9606 rogid:3LMa4f6IxjpvEoh2Hyu0hHKkY789606 rigid:Wc8pTqhAXp+ylu11AGeH1gdmEpI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86VY4 uniprotkb:Q99417 intact:EBI-3436472|uniprotkb:B3KRF0|uniprotkb:Q9C0B3|ensembl:ENSP00000322802 intact:EBI-716185|intact:EBI-2559925|uniprotkb:Q5TA64|uniprotkb:Q96HE2|uniprotkb:B2R4N0|ensembl:ENSP00000380702 psi-mi:tsyl5_human(display_long)|uniprotkb:TSPYL5(gene name)|psi-mi:TSPYL5(display_short)|uniprotkb:KIAA1750(gene name synonym) psi-mi:mycbp_human(display_long)|uniprotkb:Associate of Myc 1(gene name synonym)|uniprotkb:MYCBP(gene name)|psi-mi:MYCBP(display_short)|uniprotkb:AMY1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486370|imex:IM-26985-595 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_277047.2|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0040008"(regulation of growth)|go:"GO:0042393"(histone binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071480"(cellular response to gamma radiation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q86VY4|ensembl:ENSG00000180543(gene)|ensembl:ENST00000322128(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding) refseq:NP_036465.2|ensembl:ENSG00000214114(gene)|ensembl:ENST00000397572(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007283"(spermatogenesis)|interpro:IPR026060|mint:Q99417|rcsb pdb:2YY0 - - comment:"author score: 36" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Re2EBlbXEybC1/oghH+B067fNDM9606 rogid:jIStn1A10DDkgTuwVeKpDPJ6tIs9606 rigid:Wc8pTqhAXp+ylu11AGeH1gdmEpI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86VY4 uniprotkb:P84243 intact:EBI-3436472|uniprotkb:B3KRF0|uniprotkb:Q9C0B3|ensembl:ENSP00000322802 intact:EBI-120658|uniprotkb:P06351|uniprotkb:P33155|uniprotkb:Q5VV55|uniprotkb:Q5VV56|uniprotkb:Q66I33|uniprotkb:Q9V3W4|ensembl:ENSP00000254810|ensembl:ENSP00000355778|ensembl:ENSP00000355780|ensembl:ENSP00000355781|ensembl:ENSP00000465813|ensembl:ENSP00000466020|ensembl:ENSP00000468714|ensembl:ENSP00000499275|ensembl:ENSP00000499385|ensembl:ENSP00000499800 psi-mi:tsyl5_human(display_long)|uniprotkb:TSPYL5(gene name)|psi-mi:TSPYL5(display_short)|uniprotkb:KIAA1750(gene name synonym) psi-mi:h33_human(display_long)|uniprotkb:H3-3A(gene name)|psi-mi:H3-3A(display_short)|uniprotkb:H3-3B(gene name)|psi-mi:H3-3B(display_short)|uniprotkb:H3.3A(gene name synonym)|uniprotkb:H3.3B(gene name synonym)|uniprotkb:H3F3(gene name synonym)|uniprotkb:H3F3A(gene name synonym)|uniprotkb:H3F3B(gene name synonym)|uniprotkb:PP781(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486370|imex:IM-26985-595 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_277047.2|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0040008"(regulation of growth)|go:"GO:0042393"(histone binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071480"(cellular response to gamma radiation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q86VY4|ensembl:ENSG00000180543(gene)|ensembl:ENST00000322128(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding) refseq:NP_002098.1|refseq:NP_005315.1|rcsb pdb:4H9N|rcsb pdb:3QL9|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:3QLA|rcsb pdb:3QLC|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:4L58|rcsb pdb:4N4I|rcsb pdb:3WTP|rcsb pdb:4O62|rcsb pdb:4QQ4|rcsb pdb:4TMP|rcsb pdb:4GNE|rcsb pdb:4GNF|rcsb pdb:4U7T|rcsb pdb:4GNG|rcsb pdb:4W5A|rcsb pdb:4GU0|rcsb pdb:4GUR|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:4GUS|rcsb pdb:4GY5|rcsb pdb:5DWQ|rcsb pdb:5DX0|rcsb pdb:5JA4|rcsb pdb:5JJY|ensembl:ENSG00000132475(gene)|ensembl:ENSG00000163041(gene)|rcsb pdb:5JLB|rcsb pdb:5KDM|rcsb pdb:5X7X|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6HGT|rcsb pdb:6INQ|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6J9J|rcsb pdb:6PZV|rcsb pdb:6QXZ|rcsb pdb:6R0C|rcsb pdb:6RNY|rcsb pdb:6U04|rcsb pdb:7A08|reactome:R-HSA-427413|rcsb pdb:7CIZ|reactome:R-HSA-5250924|reactome:R-HSA-5334118|rcsb pdb:7CJ0|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-983231|rcsb pdb:7CWH|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-427359|reactome:R-HSA-427389|ensembl:ENST00000254810(transcript)|ensembl:ENST00000366813(transcript)|ensembl:ENST00000366815(transcript)|ensembl:ENST00000366816(transcript)|ensembl:ENST00000586607(transcript)|ensembl:ENST00000587560(transcript)|ensembl:ENST00000589599(transcript)|ensembl:ENST00000655399(transcript)|ensembl:ENST00000661429(transcript)|ensembl:ENST00000666609(transcript)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000786"(nucleosome)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006336"(DNA replication-independent chromatin assembly)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032200"(telomere organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000164(Histone H3)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P84243|rcsb pdb:2L43|rcsb pdb:3ASK|rcsb pdb:3ASL|rcsb pdb:3AV2|rcsb pdb:3JVK|rcsb pdb:3MUK|rcsb pdb:3MUL|dip:DIP-40046N - - comment:"author score: 40" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Re2EBlbXEybC1/oghH+B067fNDM9606 rogid:cRqA5/IBNfIbbxAnbwLqzXip20I9606 rigid:Wc8pTqhAXp+ylu11AGeH1gdmEpI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86VY4 uniprotkb:Q9UER7 intact:EBI-3436472|uniprotkb:B3KRF0|uniprotkb:Q9C0B3|ensembl:ENSP00000322802 intact:EBI-77321|ensembl:ENSP00000266000|ensembl:ENSP00000363668|ensembl:ENSP00000372539|ensembl:ENSP00000372681|ensembl:ENSP00000382014|ensembl:ENSP00000382281|ensembl:ENSP00000394108|ensembl:ENSP00000404376|ensembl:ENSP00000404623|ensembl:ENSP00000410772|uniprotkb:O14747|uniprotkb:O15141|uniprotkb:O15208|uniprotkb:Q9BWI3|uniprotkb:B4E1I3|uniprotkb:F5H082|uniprotkb:Q5STK9|uniprotkb:F5ANJ6|uniprotkb:F5ANJ7 psi-mi:tsyl5_human(display_long)|uniprotkb:TSPYL5(gene name)|psi-mi:TSPYL5(display_short)|uniprotkb:KIAA1750(gene name synonym) psi-mi:daxx_human(display_long)|uniprotkb:DAXX(gene name)|psi-mi:DAXX(display_short)|uniprotkb:BING2(gene name synonym)|uniprotkb:DAP6(gene name synonym)|uniprotkb:Daxx(gene name synonym)|uniprotkb:Fas death domain-associated protein(gene name synonym)|uniprotkb:ETS1-associated protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486370|imex:IM-26985-595 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_277047.2|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0040008"(regulation of growth)|go:"GO:0042393"(histone binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071480"(cellular response to gamma radiation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q86VY4|ensembl:ENSG00000180543(gene)|ensembl:ENST00000322128(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding) ensembl:ENSG00000206206(gene)|ensembl:ENSG00000206279(gene)|ensembl:ENSG00000227046(gene)|ensembl:ENSG00000231617(gene)|ensembl:ENSG00000204209(gene)|ensembl:ENST00000266000(transcript)|ensembl:ENST00000374542(transcript)|ensembl:ENST00000383062(transcript)|ensembl:ENST00000383194(transcript)|ensembl:ENST00000399060(transcript)|ensembl:ENST00000399344(transcript)|ensembl:ENST00000433482(transcript)|ensembl:ENST00000436311(transcript)|ensembl:ENST00000445009(transcript)|ensembl:ENST00000455860(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002039"(p53 binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0016604"(nuclear body)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030521"(androgen receptor signaling pathway)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042393"(histone binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071280"(cellular response to copper ion)|go:"GO:0072738"(cellular response to diamide)|go:"GO:0140037"(sumo-dependent protein binding)|go:"GO:0140416"(transcription regulator inhibitor activity)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1903936"(cellular response to sodium arsenite)|interpro:IPR005012(Daxx protein)|interpro:IPR031333|interpro:IPR038298|mint:Q9UER7|rcsb pdb:2KQS|rcsb pdb:2KZS|rcsb pdb:2KZU|rcsb pdb:4H9N|rcsb pdb:4H9O|rcsb pdb:4H9P|rcsb pdb:4H9Q|rcsb pdb:4H9R|rcsb pdb:4H9S|rcsb pdb:4HGA|rcsb pdb:5GRQ|rcsb pdb:5KDM|rcsb pdb:5Y18|rcsb pdb:5Y6O|reactome:R-HSA-3899300|reactome:R-HSA-6804757|reactome:R-HSA-9609690|reactome:R-HSA-9670095|reactome:R-HSA-9670613|reactome:R-HSA-9670615|refseq:NP_001135441.1|refseq:NP_001341.1|refseq:NP_001241646.1|dip:DIP-27628N - - comment:"author score: 43" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Re2EBlbXEybC1/oghH+B067fNDM9606 rogid:lM3F/1ay7qvt8NkGWvgfSvBX1qQ9606 rigid:Wc8pTqhAXp+ylu11AGeH1gdmEpI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q86VY4 uniprotkb:P62750 intact:EBI-3436472|uniprotkb:B3KRF0|uniprotkb:Q9C0B3|ensembl:ENSP00000322802 intact:EBI-353254|uniprotkb:P29316|uniprotkb:Q92774|uniprotkb:P39024|uniprotkb:B2R5B2|ensembl:ENSP00000389103 psi-mi:tsyl5_human(display_long)|uniprotkb:TSPYL5(gene name)|psi-mi:TSPYL5(display_short)|uniprotkb:KIAA1750(gene name synonym) psi-mi:rl23a_human(display_long)|uniprotkb:RPL23A(gene name)|psi-mi:RPL23A(display_short)|uniprotkb:Large ribosomal subunit protein uL23(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486370|imex:IM-26985-595 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_277047.2|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0040008"(regulation of growth)|go:"GO:0042393"(histone binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0071480"(cellular response to gamma radiation)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q86VY4|ensembl:ENSG00000180543(gene)|ensembl:ENST00000322128(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding) reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|refseq:NP_000975.2|ensembl:ENSG00000198242(gene)|ensembl:ENST00000422514(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904841"(TORC2 complex binding)|interpro:IPR001014(Ribosomal protein L23, conserved site)|interpro:IPR005633(Ribosomal protein L23/L25, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR013025(Ribosomal protein L25/L23)|interpro:IPR019985|mint:P62750|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS - - comment:"author score: 44" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Re2EBlbXEybC1/oghH+B067fNDM9606 rogid:lA1ubRFO9/Tl54Z1dKUzoCKvpAo9606 rigid:Wc8pTqhAXp+ylu11AGeH1gdmEpI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N831 uniprotkb:P60660 intact:EBI-12023322|intact:EBI-28986284|ensembl:ENSP00000417919|uniprotkb:Q6NUJ3 intact:EBI-300817|uniprotkb:P16475|uniprotkb:P24572|uniprotkb:P24573|uniprotkb:Q12790|ensembl:ENSP00000446955|ensembl:ENSP00000448101|uniprotkb:Q6IAZ0|uniprotkb:Q6IPY5|uniprotkb:Q561V9 psi-mi:tsyl6_human(display_long)|uniprotkb:TSPYL6(gene name)|psi-mi:TSPYL6(display_short) psi-mi:myl6_human(display_long)|uniprotkb:MYL6(gene name)|psi-mi:MYL6(display_short)|uniprotkb:Smooth muscle and nonmuscle myosin light chain alkali 6(gene name synonym)|uniprotkb:Myosin light chain alkali 3(gene name synonym)|uniprotkb:Myosin light chain 3(gene name synonym)|uniprotkb:17 kDa myosin light chain(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486451|imex:IM-26985-375 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000178021(gene)|ensembl:ENST00000317802(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0042393"(histone binding)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q8N831|refseq:NP_001003937.2|ensembl:ENSP00000417919 ensembl:ENSG00000092841(gene)|ensembl:ENST00000548293(transcript)|ensembl:ENST00000550697(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0006936"(muscle contraction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0016020"(membrane)|go:"GO:0016459"(myosin complex)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0030049"(muscle filament sliding)|go:"GO:0031982"(vesicle)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|mint:P60660|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-445355|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|refseq:NP_066299.2|refseq:NP_524147.2 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Z4fnpvLfPCfc/z3JglCvoR3wkhk9606 rogid:LhE3NUqcuHlOla13C0vjnFZfzy89606 rigid:0IkqCIY8WoThWfcD9G0rNiik6Hc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N831 uniprotkb:O14950 intact:EBI-12023322|intact:EBI-28986284|ensembl:ENSP00000417919|uniprotkb:Q6NUJ3 intact:EBI-1642165|uniprotkb:D3DUH6|intact:EBI-2826593|uniprotkb:Q7Z5Z4|uniprotkb:Q13182|ensembl:ENSP00000237500|ensembl:ENSP00000383037|ensembl:ENSP00000463559|ensembl:ENSP00000464464|ensembl:ENSP00000496809 psi-mi:tsyl6_human(display_long)|uniprotkb:TSPYL6(gene name)|psi-mi:TSPYL6(display_short) psi-mi:ml12b_human(display_long)|uniprotkb:MYL12B(gene name)|psi-mi:MYL12B(display_short)|uniprotkb:MRLC2(gene name synonym)|uniprotkb:Myosin regulatory light chain 2-B, smooth muscle isoform(gene name synonym)|uniprotkb:MLC-2A(gene name synonym)|uniprotkb:SHUJUN-1(gene name synonym)|uniprotkb:MYLC2B(gene name synonym)|uniprotkb:Myosin regulatory light chain MRLC2(gene name synonym)|uniprotkb:Myosin regulatory light chain 20 kDa(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486451|imex:IM-26985-375 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000178021(gene)|ensembl:ENST00000317802(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0042393"(histone binding)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q8N831|refseq:NP_001003937.2|ensembl:ENSP00000417919 refseq:NP_001138416.1|refseq:NP_001138417.1|refseq:NP_291024.1|refseq:NP_001289978.1|ensembl:ENSG00000118680(gene)|ensembl:ENST00000237500(transcript)|ensembl:ENST00000400175(transcript)|ensembl:ENST00000581193(transcript)|ensembl:ENST00000584539(transcript)|ensembl:ENST00000648965(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016460"(myosin II complex)|go:"GO:0030018"(Z disc)|go:"GO:0032036"(myosin heavy chain binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR015070(Region of unknown function DUF1880)|interpro:IPR018247|mint:O14950|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-445355|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Z4fnpvLfPCfc/z3JglCvoR3wkhk9606 rogid:5jOP3J5TW0eU9zwalQ2S4Oist4k9606 rigid:0IkqCIY8WoThWfcD9G0rNiik6Hc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N831 uniprotkb:Q8TF66 intact:EBI-12023322|intact:EBI-28986284|ensembl:ENSP00000417919|uniprotkb:Q6NUJ3 intact:EBI-2511695|uniprotkb:Q7RTN7|uniprotkb:Q495Q6|ensembl:ENSP00000306276 psi-mi:tsyl6_human(display_long)|uniprotkb:TSPYL6(gene name)|psi-mi:TSPYL6(display_short) psi-mi:lrc15_human(display_long)|uniprotkb:LRRC15(gene name)|psi-mi:LRRC15(display_short)|uniprotkb:Leucine-rich repeat protein induced by beta-amyloid homolog(gene name synonym)|uniprotkb:LIB(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486451|imex:IM-26985-375 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000178021(gene)|ensembl:ENST00000317802(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0042393"(histone binding)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q8N831|refseq:NP_001003937.2|ensembl:ENSP00000417919 refseq:NP_001128529.2|refseq:NP_570843.2|ensembl:ENSG00000172061(gene)|ensembl:ENST00000347624(transcript)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005518"(collagen binding)|go:"GO:0005615"(extracellular space)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031012"(extracellular matrix)|go:"GO:0043236"(laminin binding)|go:"GO:0046813"(receptor-mediated virion attachment to host cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|mint:Q8TF66 - - comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Z4fnpvLfPCfc/z3JglCvoR3wkhk9606 rogid:rU8egLkPqRi0D9QTtIQqKje1+y49606 rigid:0IkqCIY8WoThWfcD9G0rNiik6Hc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N831 uniprotkb:Q9GZR7 intact:EBI-12023322|intact:EBI-28986284|ensembl:ENSP00000417919|uniprotkb:Q6NUJ3 intact:EBI-713081|ensembl:ENSP00000481495|ensembl:ENSP00000482106|uniprotkb:E7EMJ4|uniprotkb:Q4V9L5 psi-mi:tsyl6_human(display_long)|uniprotkb:TSPYL6(gene name)|psi-mi:TSPYL6(display_short) psi-mi:ddx24_human(display_long)|uniprotkb:DEAD box protein 24(gene name synonym)|uniprotkb:DDX24(gene name)|psi-mi:DDX24(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486451|imex:IM-26985-375 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000178021(gene)|ensembl:ENST00000317802(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0042393"(histone binding)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q8N831|refseq:NP_001003937.2|ensembl:ENSP00000417919 ensembl:ENSG00000089737(gene)|ensembl:ENSG00000273761(gene)|ensembl:ENST00000613280(transcript)|ensembl:ENST00000621632(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0016070"(RNA metabolic process)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR027417|mint:Q9GZR7|refseq:NP_065147.1|dip:DIP-47301N - - comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Z4fnpvLfPCfc/z3JglCvoR3wkhk9606 rogid:n9gQabTC50Y/LtGMAMFNVgj12as9606 rigid:0IkqCIY8WoThWfcD9G0rNiik6Hc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N831 uniprotkb:Q9H2G4 intact:EBI-12023322|intact:EBI-28986284|ensembl:ENSP00000417919|uniprotkb:Q6NUJ3 intact:EBI-947459|uniprotkb:O94799|uniprotkb:Q96DG7|uniprotkb:Q9BZW6|ensembl:ENSP00000364591 psi-mi:tsyl6_human(display_long)|uniprotkb:TSPYL6(gene name)|psi-mi:TSPYL6(display_short) psi-mi:tsyl2_human(display_long)|uniprotkb:TSPYL2(gene name)|psi-mi:TSPYL2(display_short)|uniprotkb:Differentially-expressed nucleolar TGF-beta1 target protein(gene name synonym)|uniprotkb:Cell division autoantigen 1(gene name synonym)|uniprotkb:Cutaneous T-cell lymphoma-associated antigen se20-4(gene name synonym)|uniprotkb:Nuclear protein of 79 kDa(gene name synonym)|uniprotkb:CDA1(gene name synonym)|uniprotkb:DENTT(gene name synonym)|uniprotkb:TSPX(gene name synonym)|uniprotkb:HRIHFB2216(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486451|imex:IM-26985-375 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000178021(gene)|ensembl:ENST00000317802(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0042393"(histone binding)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q8N831|refseq:NP_001003937.2|ensembl:ENSP00000417919 refseq:NP_071400.1|ensembl:ENSP00000364591|ensembl:ENSG00000184205(gene)|ensembl:ENST00000375442(transcript)|go:"GO:0000182"(rDNA binding)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0042393"(histone binding)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045859"(regulation of protein kinase activity)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q9H2G4|reactome:R-HSA-381038 - - comment:"author score: 27" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Z4fnpvLfPCfc/z3JglCvoR3wkhk9606 rogid:wVPRgfWOwBORcPzBZeyn9S9cqq09606 rigid:0IkqCIY8WoThWfcD9G0rNiik6Hc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N831 uniprotkb:P61289 intact:EBI-12023322|intact:EBI-28986284|ensembl:ENSP00000417919|uniprotkb:Q6NUJ3 intact:EBI-355546|uniprotkb:O35563|uniprotkb:P97373|uniprotkb:Q12920|uniprotkb:Q13172|uniprotkb:Q9BQD9|uniprotkb:A8K9A3|ensembl:ENSP00000466794 psi-mi:tsyl6_human(display_long)|uniprotkb:TSPYL6(gene name)|psi-mi:TSPYL6(display_short) psi-mi:psme3_human(display_long)|uniprotkb:PSME3(gene name)|psi-mi:PSME3(display_short)|uniprotkb:Proteasome activator 28 subunit gamma(gene name synonym)|uniprotkb:Activator of multicatalytic protease subunit 3(gene name synonym)|uniprotkb:11S regulator complex subunit gamma(gene name synonym)|uniprotkb:Ki nuclear autoantigen(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486451|imex:IM-26985-375 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000178021(gene)|ensembl:ENST00000317802(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0042393"(histone binding)|interpro:IPR002164("Nucleosome assembly protein (NAP)")|interpro:IPR037231|mint:Q8N831|refseq:NP_001003937.2|ensembl:ENSP00000417919 refseq:NP_005780.2|refseq:NP_789839.1|ensembl:ENSG00000131467(gene)|ensembl:ENST00000590720(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0008537"(proteasome activator complex)|go:"GO:0010950"(positive regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0061133"(endopeptidase activator activity)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR003185(Proteasome activator pa28, REG alpha subunit)|interpro:IPR003186(Proteasome activator pa28, REG beta subunit)|interpro:IPR009077(Proteasome activator pa28, REG alpha/beta subunit)|interpro:IPR036252|interpro:IPR036996|interpro:IPR036997|mint:P61289|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168 - - comment:"author score: 44" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:Z4fnpvLfPCfc/z3JglCvoR3wkhk9606 rogid:6EQY2Kj3Juf++m4eBDzPWMgbC2k9606 rigid:0IkqCIY8WoThWfcD9G0rNiik6Hc false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UGJ1 uniprotkb:P32322 intact:EBI-1052544|uniprotkb:Q969X3|uniprotkb:Q9NVF0|uniprotkb:B3KNK6|ensembl:ENSP00000260383 intact:EBI-848624|uniprotkb:B4DMU0|uniprotkb:Q6FHI4|uniprotkb:Q96DI6|uniprotkb:A6NFM2|uniprotkb:Q9HBQ4|ensembl:ENSP00000328858|ensembl:ENSP00000479793 psi-mi:gcp4_human(display_long)|uniprotkb:Gamma-ring complex protein 76 kDa(gene name synonym)|uniprotkb:TUBGCP4(gene name)|psi-mi:TUBGCP4(display_short)|uniprotkb:76P(gene name synonym)|uniprotkb:GCP4(gene name synonym) psi-mi:p5cr1_human(display_long)|uniprotkb:PYCR1(gene name)|psi-mi:PYCR1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486484|imex:IM-26985-295 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055259.2|refseq:NP_001273343.1|refseq:XP_011519757.1|ensembl:ENSG00000137822(gene)|ensembl:ENST00000260383(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0055037"(recycling endosome)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|interpro:IPR042241|mint:Q9UGJ1|rcsb pdb:3RIP|rcsb pdb:6V69|rcsb pdb:6V6S|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320|dip:DIP-50536N refseq:NP_008838.2|refseq:XP_011521885.1|refseq:XP_011521886.1|refseq:NP_001269209.1|refseq:NP_001269210.1|refseq:XP_005256438.1|refseq:NP_722546.1|ensembl:ENSG00000183010(gene)|ensembl:ENST00000329875(transcript)|ensembl:ENST00000619204(transcript)|go:"GO:0004735"(pyrroline-5-carboxylate reductase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006561"(proline biosynthetic process)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0055129"(L-proline biosynthetic process)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|interpro:IPR000304(Delta 1-pyrroline-5-carboxylate reductase)|interpro:IPR008927(6-phosphogluconate dehydrogenase, C-terminal-like)|interpro:IPR028939|interpro:IPR029036|interpro:IPR036291|mint:P32322|rcsb pdb:2GER|rcsb pdb:2GR9|rcsb pdb:2GRA|rcsb pdb:2IZZ|rcsb pdb:5UAT|rcsb pdb:5UAU|rcsb pdb:5UAV|rcsb pdb:5UAW|rcsb pdb:5UAX|rcsb pdb:6XOZ|rcsb pdb:6XP0|rcsb pdb:6XP1|rcsb pdb:6XP2|rcsb pdb:6XP3|reactome:R-HSA-8964539 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5pAlGB03qeX0CJ0etjcLInwgaZQ9606 rogid:+hos1FhDb7QofDBHXEBGlWxv+z09606 rigid:JODsASHB53LJJClfTrNPgI4uEa4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UGJ1 uniprotkb:Q9BQP7 intact:EBI-1052544|uniprotkb:Q969X3|uniprotkb:Q9NVF0|uniprotkb:B3KNK6|ensembl:ENSP00000260383 intact:EBI-739561|uniprotkb:Q96SW3|uniprotkb:B2RDG5|uniprotkb:D3DW29|ensembl:ENSP00000366939 psi-mi:gcp4_human(display_long)|uniprotkb:Gamma-ring complex protein 76 kDa(gene name synonym)|uniprotkb:TUBGCP4(gene name)|psi-mi:TUBGCP4(display_short)|uniprotkb:76P(gene name synonym)|uniprotkb:GCP4(gene name synonym) psi-mi:mgme1_human(display_long)|uniprotkb:DDK1(gene name synonym)|uniprotkb:MGME1(gene name)|psi-mi:MGME1(display_short)|uniprotkb:C20orf72(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486484|imex:IM-26985-295 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055259.2|refseq:NP_001273343.1|refseq:XP_011519757.1|ensembl:ENSG00000137822(gene)|ensembl:ENST00000260383(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0055037"(recycling endosome)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|interpro:IPR042241|mint:Q9UGJ1|rcsb pdb:3RIP|rcsb pdb:6V69|rcsb pdb:6V6S|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320|dip:DIP-50536N refseq:NP_443097.1|ensembl:ENSG00000125871(gene)|ensembl:ENST00000377710(transcript)|go:"GO:0000002"(mitochondrial genome maintenance)|go:"GO:0005739"(mitochondrion)|go:"GO:0006264"(mitochondrial DNA replication)|go:"GO:0008297"(single-stranded DNA exodeoxyribonuclease activity)|go:"GO:0043504"(mitochondrial DNA repair)|interpro:IPR011335(Restriction endonuclease, type II-like, core)|interpro:IPR011604(Exonuclease, phage-type/RecB, C-terminal)|interpro:IPR038726|mint:Q9BQP7|rcsb pdb:5ZYT|rcsb pdb:5ZYU|rcsb pdb:5ZYV|rcsb pdb:5ZYW|refseq:XP_016883616.1|refseq:XP_016883617.1|refseq:NP_001297267.1|refseq:NP_001297268.1 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5pAlGB03qeX0CJ0etjcLInwgaZQ9606 rogid:u0259b2csxQpZ6ZYN/Q1HGeKChk9606 rigid:JODsASHB53LJJClfTrNPgI4uEa4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UGJ1 uniprotkb:Q96DV4 intact:EBI-1052544|uniprotkb:Q969X3|uniprotkb:Q9NVF0|uniprotkb:B3KNK6|ensembl:ENSP00000260383 intact:EBI-720441|uniprotkb:Q96Q66|uniprotkb:Q9P0B9|uniprotkb:B3KN96|ensembl:ENSP00000308275 psi-mi:gcp4_human(display_long)|uniprotkb:Gamma-ring complex protein 76 kDa(gene name synonym)|uniprotkb:TUBGCP4(gene name)|psi-mi:TUBGCP4(display_short)|uniprotkb:76P(gene name synonym)|uniprotkb:GCP4(gene name synonym) psi-mi:rm38_human(display_long)|uniprotkb:MRPL38(gene name)|psi-mi:MRPL38(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein mL38(gene name synonym)|uniprotkb:HSPC262(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486484|imex:IM-26985-295 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055259.2|refseq:NP_001273343.1|refseq:XP_011519757.1|ensembl:ENSG00000137822(gene)|ensembl:ENST00000260383(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0055037"(recycling endosome)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|interpro:IPR042241|mint:Q9UGJ1|rcsb pdb:3RIP|rcsb pdb:6V69|rcsb pdb:6V6S|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320|dip:DIP-50536N refseq:NP_115867.2|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|rcsb pdb:6ZSC|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000204316(gene)|ensembl:ENST00000309352(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|interpro:IPR008914(Phosphatidylethanolamine-binding protein PEBP)|interpro:IPR035810|interpro:IPR036610|mint:Q96DV4|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5pAlGB03qeX0CJ0etjcLInwgaZQ9606 rogid:U9R8ZJYdURLjkBNd5LZOt4wsWD89606 rigid:JODsASHB53LJJClfTrNPgI4uEa4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UGJ1 uniprotkb:Q13084 intact:EBI-1052544|uniprotkb:Q969X3|uniprotkb:Q9NVF0|uniprotkb:B3KNK6|ensembl:ENSP00000260383 intact:EBI-723426|uniprotkb:Q4TT39|uniprotkb:Q96S26|uniprotkb:Q9BQD8|uniprotkb:Q9BR04|ensembl:ENSP00000199706|ensembl:ENSP00000374326|ensembl:ENSP00000497004|uniprotkb:B2RCM4|uniprotkb:D3DU46 psi-mi:gcp4_human(display_long)|uniprotkb:Gamma-ring complex protein 76 kDa(gene name synonym)|uniprotkb:TUBGCP4(gene name)|psi-mi:TUBGCP4(display_short)|uniprotkb:76P(gene name synonym)|uniprotkb:GCP4(gene name synonym) psi-mi:rm28_human(display_long)|uniprotkb:Melanoma antigen p15(gene name synonym)|uniprotkb:MRPL28(gene name)|psi-mi:MRPL28(display_short)|uniprotkb:MAAT1(gene name synonym)|uniprotkb:Melanoma-associated antigen recognized by T-lymphocytes(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein bL28m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486484|imex:IM-26985-295 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055259.2|refseq:NP_001273343.1|refseq:XP_011519757.1|ensembl:ENSG00000137822(gene)|ensembl:ENST00000260383(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0055037"(recycling endosome)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|interpro:IPR042241|mint:Q9UGJ1|rcsb pdb:3RIP|rcsb pdb:6V69|rcsb pdb:6V6S|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320|dip:DIP-50536N refseq:NP_006419.2|rcsb pdb:3J7Y|ensembl:ENSG00000086504(gene)|ensembl:ENST00000199706(transcript)|ensembl:ENST00000389675(transcript)|ensembl:ENST00000648346(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|interpro:IPR026569|interpro:IPR034704|interpro:IPR037147|mint:Q13084|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:XP_011520653.1|refseq:XP_005255098.1|dip:DIP-61135N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5pAlGB03qeX0CJ0etjcLInwgaZQ9606 rogid:rgjK24sQlABM210ZM7T9mT2wxKs9606 rigid:JODsASHB53LJJClfTrNPgI4uEa4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UGJ1 uniprotkb:Q8IXM3 intact:EBI-1052544|uniprotkb:Q969X3|uniprotkb:Q9NVF0|uniprotkb:B3KNK6|ensembl:ENSP00000260383 intact:EBI-912501|uniprotkb:Q96Q49|ensembl:ENSP00000360498 psi-mi:gcp4_human(display_long)|uniprotkb:Gamma-ring complex protein 76 kDa(gene name synonym)|uniprotkb:TUBGCP4(gene name)|psi-mi:TUBGCP4(display_short)|uniprotkb:76P(gene name synonym)|uniprotkb:GCP4(gene name synonym) psi-mi:rm41_human(display_long)|uniprotkb:MRPL27(gene name synonym)|uniprotkb:39S ribosomal protein L27 homolog(gene name synonym)|uniprotkb:MRP-L27 homolog(gene name synonym)|uniprotkb:Bcl-2-interacting mitochondrial ribosomal protein L41(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 3 protein(gene name synonym)|uniprotkb:MRPL41(gene name)|psi-mi:MRPL41(display_short)|uniprotkb:BMRP(gene name synonym)|uniprotkb:RPML27(gene name synonym)|uniprotkb:PIG3(orf name)|uniprotkb:Mitochondrial large ribosomal subunit protein mL41(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486484|imex:IM-26985-295 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055259.2|refseq:NP_001273343.1|refseq:XP_011519757.1|ensembl:ENSG00000137822(gene)|ensembl:ENST00000260383(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0055037"(recycling endosome)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|interpro:IPR042241|mint:Q9UGJ1|rcsb pdb:3RIP|rcsb pdb:6V69|rcsb pdb:6V6S|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320|dip:DIP-50536N refseq:NP_115866.1|ensembl:ENSG00000182154(gene)|ensembl:ENST00000371443(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR019189|mint:Q8IXM3|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5pAlGB03qeX0CJ0etjcLInwgaZQ9606 rogid:1qftd9Vr6Rsymp6hgM29FeOvChA9606 rigid:JODsASHB53LJJClfTrNPgI4uEa4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UGJ1 uniprotkb:Q9Y241 intact:EBI-1052544|uniprotkb:Q969X3|uniprotkb:Q9NVF0|uniprotkb:B3KNK6|ensembl:ENSP00000260383 intact:EBI-1051940|uniprotkb:Q9UFZ2|ensembl:ENSP00000319393|ensembl:ENSP00000402160 psi-mi:gcp4_human(display_long)|uniprotkb:Gamma-ring complex protein 76 kDa(gene name synonym)|uniprotkb:TUBGCP4(gene name)|psi-mi:TUBGCP4(display_short)|uniprotkb:76P(gene name synonym)|uniprotkb:GCP4(gene name synonym) psi-mi:hig1a_human(display_long)|uniprotkb:Hypoxia-inducible gene 1 protein(gene name synonym)|uniprotkb:HIGD1A(gene name)|psi-mi:HIGD1A(display_short)|uniprotkb:HIG1(gene name synonym)|uniprotkb:RCF1 homolog A(gene name synonym)|uniprotkb:HSPC010(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486484|imex:IM-26985-295 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055259.2|refseq:NP_001273343.1|refseq:XP_011519757.1|ensembl:ENSG00000137822(gene)|ensembl:ENST00000260383(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0055037"(recycling endosome)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|interpro:IPR042241|mint:Q9UGJ1|rcsb pdb:3RIP|rcsb pdb:6V69|rcsb pdb:6V6S|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320|dip:DIP-50536N refseq:NP_001093138.1|refseq:NP_001093139.1|refseq:NP_054775.2|ensembl:ENSG00000181061(gene)|ensembl:ENST00000321331(transcript)|ensembl:ENST00000418900(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0070469"(respirasome)|go:"GO:0097250"(mitochondrial respirasome assembly)|interpro:IPR007667(Hypoxia induced protein conserved region)|mint:Q9Y241|rcsb pdb:2LOM|reactome:R-HSA-1234158 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5pAlGB03qeX0CJ0etjcLInwgaZQ9606 rogid:xFklQUZRMs1m+6gbSJu2tKVz0Dk9606 rigid:JODsASHB53LJJClfTrNPgI4uEa4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UGJ1 uniprotkb:P24539 intact:EBI-1052544|uniprotkb:Q969X3|uniprotkb:Q9NVF0|uniprotkb:B3KNK6|ensembl:ENSP00000260383 intact:EBI-1044810|uniprotkb:Q9BQ68|uniprotkb:Q9BRU8|ensembl:ENSP00000358737 psi-mi:gcp4_human(display_long)|uniprotkb:Gamma-ring complex protein 76 kDa(gene name synonym)|uniprotkb:TUBGCP4(gene name)|psi-mi:TUBGCP4(display_short)|uniprotkb:76P(gene name synonym)|uniprotkb:GCP4(gene name synonym) psi-mi:at5f1_human(display_long)|uniprotkb:ATP5PB(gene name)|psi-mi:ATP5PB(display_short)|uniprotkb:ATP synthase peripheral stalk-membrane subunit b(gene name synonym)|uniprotkb:"ATP synthase proton-transporting mitochondrial F(0) complex subunit B1"(gene name synonym)|uniprotkb:ATP synthase subunit b(gene name synonym)|uniprotkb:ATP5F1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486484|imex:IM-26985-295 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055259.2|refseq:NP_001273343.1|refseq:XP_011519757.1|ensembl:ENSG00000137822(gene)|ensembl:ENST00000260383(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0055037"(recycling endosome)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|interpro:IPR042241|mint:Q9UGJ1|rcsb pdb:3RIP|rcsb pdb:6V69|rcsb pdb:6V6S|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320|dip:DIP-50536N refseq:NP_001679.2|ensembl:ENSG00000116459(gene)|ensembl:ENST00000369722(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0021762"(substantia nigra development)|interpro:IPR008688(ATPase, F0 complex, subunit B, mitochondrial)|interpro:IPR013837(ATPase, F0 complex subunit B, mitochondrial, metazoa)|mint:P24539|reactome:R-HSA-163210|reactome:R-HSA-8949613|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport) - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5pAlGB03qeX0CJ0etjcLInwgaZQ9606 rogid:n1HuorsLzONcID7ccOL9qEsODLE9606 rigid:JODsASHB53LJJClfTrNPgI4uEa4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UGJ1 uniprotkb:P58557 intact:EBI-1052544|uniprotkb:Q969X3|uniprotkb:Q9NVF0|uniprotkb:B3KNK6|ensembl:ENSP00000260383 intact:EBI-2114647|uniprotkb:D3DSN2|uniprotkb:B7WPA9|uniprotkb:B7WPF7|ensembl:ENSP00000329614|ensembl:ENSP00000380805|ensembl:ENSP00000380813 psi-mi:gcp4_human(display_long)|uniprotkb:Gamma-ring complex protein 76 kDa(gene name synonym)|uniprotkb:TUBGCP4(gene name)|psi-mi:TUBGCP4(display_short)|uniprotkb:76P(gene name synonym)|uniprotkb:GCP4(gene name synonym) psi-mi:ybey_human(display_long)|uniprotkb:YBEY(gene name)|psi-mi:YBEY(display_short)|uniprotkb:C21orf57(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486484|imex:IM-26985-295 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055259.2|refseq:NP_001273343.1|refseq:XP_011519757.1|ensembl:ENSG00000137822(gene)|ensembl:ENST00000260383(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0055037"(recycling endosome)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|interpro:IPR042241|mint:Q9UGJ1|rcsb pdb:3RIP|rcsb pdb:6V69|rcsb pdb:6V6S|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320|dip:DIP-50536N refseq:NP_478061.1|refseq:NP_001300951.1|refseq:NP_001300952.1|refseq:NP_001300953.1|refseq:NP_001300954.1|refseq:NP_001300955.1|ensembl:ENSG00000182362(gene)|ensembl:ENST00000329319(transcript)|ensembl:ENST00000397691(transcript)|ensembl:ENST00000397701(transcript)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0006364"(rRNA processing)|go:"GO:0046872"(metal ion binding)|interpro:IPR002036(Protein of unknown function UPF0054)|interpro:IPR020549|interpro:IPR023091|mint:P58557 - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5pAlGB03qeX0CJ0etjcLInwgaZQ9606 rogid:VOjeUF0iThxy1T2ywZGHB8ILorc9606 rigid:JODsASHB53LJJClfTrNPgI4uEa4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UGJ1 uniprotkb:O15269 intact:EBI-1052544|uniprotkb:Q969X3|uniprotkb:Q9NVF0|uniprotkb:B3KNK6|ensembl:ENSP00000260383 intact:EBI-1044323|uniprotkb:Q5VWB4|uniprotkb:A8K681|uniprotkb:Q96IX6|ensembl:ENSP00000262554 psi-mi:gcp4_human(display_long)|uniprotkb:Gamma-ring complex protein 76 kDa(gene name synonym)|uniprotkb:TUBGCP4(gene name)|psi-mi:TUBGCP4(display_short)|uniprotkb:76P(gene name synonym)|uniprotkb:GCP4(gene name synonym) psi-mi:sptc1_human(display_long)|uniprotkb:Serine-palmitoyl-CoA transferase 1(gene name synonym)|uniprotkb:Long chain base biosynthesis protein 1(gene name synonym)|uniprotkb:SPTLC1(gene name)|psi-mi:SPTLC1(display_short)|uniprotkb:LCB1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486484|imex:IM-26985-295 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055259.2|refseq:NP_001273343.1|refseq:XP_011519757.1|ensembl:ENSG00000137822(gene)|ensembl:ENST00000260383(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0055037"(recycling endosome)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|interpro:IPR042241|mint:Q9UGJ1|rcsb pdb:3RIP|rcsb pdb:6V69|rcsb pdb:6V6S|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320|dip:DIP-50536N refseq:NP_006406.1|refseq:NP_847894.1|refseq:NP_001268232.1|ensembl:ENSG00000090054(gene)|ensembl:ENST00000262554(transcript)|go:"GO:0004758"(serine C-palmitoyltransferase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006665"(sphingolipid metabolic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017059"(serine C-palmitoyltransferase complex)|go:"GO:0030148"(sphingolipid biosynthetic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0035339"(SPOTS complex)|go:"GO:0046512"(sphingosine biosynthetic process)|go:"GO:0046513"(ceramide biosynthetic process)|go:"GO:1904504"(positive regulation of lipophagy)|go:"GO:1904649"(regulation of fat cell apoptotic process)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:O15269|rcsb pdb:6M4N|rcsb pdb:6M4O|rcsb pdb:7CQI|rcsb pdb:7CQK|rcsb pdb:7K0I|rcsb pdb:7K0J|rcsb pdb:7K0K|rcsb pdb:7K0L|rcsb pdb:7K0M|rcsb pdb:7K0N|rcsb pdb:7K0O|rcsb pdb:7K0P|rcsb pdb:7K0Q|reactome:R-HSA-1660661|dip:DIP-45626N - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5pAlGB03qeX0CJ0etjcLInwgaZQ9606 rogid:M/O7lbdRcUwB+r1wpHj2EtSD+kI9606 rigid:JODsASHB53LJJClfTrNPgI4uEa4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UGJ1 uniprotkb:P56134 intact:EBI-1052544|uniprotkb:Q969X3|uniprotkb:Q9NVF0|uniprotkb:B3KNK6|ensembl:ENSP00000260383 intact:EBI-712794|ensembl:ENSP00000292475|uniprotkb:O76079|uniprotkb:Q96L83|uniprotkb:Q9BTI8|uniprotkb:C9J8H9|uniprotkb:F8W7V3|intact:EBI-11047094|uniprotkb:Q6IBB3 psi-mi:gcp4_human(display_long)|uniprotkb:Gamma-ring complex protein 76 kDa(gene name synonym)|uniprotkb:TUBGCP4(gene name)|psi-mi:TUBGCP4(display_short)|uniprotkb:76P(gene name synonym)|uniprotkb:GCP4(gene name synonym) psi-mi:atpk_human(display_long)|uniprotkb:ATP5MF(gene name)|psi-mi:ATP5MF(display_short)|uniprotkb:ATP synthase membrane subunit f(gene name synonym)|uniprotkb:ATP5J2(gene name synonym)|uniprotkb:ATP5JL(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486484|imex:IM-26985-295 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055259.2|refseq:NP_001273343.1|refseq:XP_011519757.1|ensembl:ENSG00000137822(gene)|ensembl:ENST00000260383(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0055037"(recycling endosome)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|interpro:IPR042241|mint:Q9UGJ1|rcsb pdb:3RIP|rcsb pdb:6V69|rcsb pdb:6V6S|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320|dip:DIP-50536N ensembl:ENSG00000241468(gene)|ensembl:ENST00000292475(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|go:"GO:1902600"(proton transmembrane transport)|interpro:IPR019344|mint:P56134|reactome:R-HSA-163210|reactome:R-HSA-8949613|refseq:NP_001003713.1|refseq:NP_004880.1|refseq:NP_001003714.1|refseq:NP_001034267.1 - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5pAlGB03qeX0CJ0etjcLInwgaZQ9606 rogid:+WS7rjFef6JE+mlZ4Q8TF2A+G0E9606 rigid:JODsASHB53LJJClfTrNPgI4uEa4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UGJ1 uniprotkb:Q9Y2Y1 intact:EBI-1052544|uniprotkb:Q969X3|uniprotkb:Q9NVF0|uniprotkb:B3KNK6|ensembl:ENSP00000260383 intact:EBI-11023785|ensembl:ENSP00000293860|uniprotkb:Q96S35|uniprotkb:Q1W6H4 psi-mi:gcp4_human(display_long)|uniprotkb:Gamma-ring complex protein 76 kDa(gene name synonym)|uniprotkb:TUBGCP4(gene name)|psi-mi:TUBGCP4(display_short)|uniprotkb:76P(gene name synonym)|uniprotkb:GCP4(gene name synonym) psi-mi:rpc10_human(display_long)|uniprotkb:POLR3K(gene name)|psi-mi:POLR3K(display_short)|uniprotkb:DNA-directed RNA polymerase III subunit K(gene name synonym)|uniprotkb:RNA polymerase III 12.5 kDa subunit(gene name synonym)|uniprotkb:RNA polymerase III subunit C11(gene name synonym)|uniprotkb:RPC11(gene name synonym)|uniprotkb:My010(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486484|imex:IM-26985-295 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055259.2|refseq:NP_001273343.1|refseq:XP_011519757.1|ensembl:ENSG00000137822(gene)|ensembl:ENST00000260383(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0055037"(recycling endosome)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|interpro:IPR042241|mint:Q9UGJ1|rcsb pdb:3RIP|rcsb pdb:6V69|rcsb pdb:6V6S|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320|dip:DIP-50536N ensembl:ENSG00000161980(gene)|ensembl:ENST00000293860(transcript)|go:"GO:0003676"(nucleic acid binding)|refseq:NP_057394.3|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005666"(RNA polymerase III complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0006383"(transcription by RNA polymerase III)|go:"GO:0006386"(termination of RNA polymerase III transcription)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042779"(tRNA 3'-trailer cleavage)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|interpro:IPR001222(Zinc finger, TFIIS-type)|interpro:IPR001529(DNA-directed RNA polymerase, M/15 kDa subunit)|interpro:IPR012164(DNA-directed RNA polymerase, subunit C11/M/9)|interpro:IPR019761|interpro:IPR034014|mint:Q9Y2Y1|rcsb pdb:7A6H|rcsb pdb:7AE1|rcsb pdb:7AE3|rcsb pdb:7AEA|rcsb pdb:7AST|rcsb pdb:7D58|rcsb pdb:7D59|rcsb pdb:7DN3|rcsb pdb:7DU2|reactome:R-HSA-1834949|reactome:R-HSA-73780|reactome:R-HSA-73980|reactome:R-HSA-749476|reactome:R-HSA-76061|reactome:R-HSA-76066|reactome:R-HSA-76071 - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5pAlGB03qeX0CJ0etjcLInwgaZQ9606 rogid:26KXQBPLU2oVOA1DSPeu4y5LjLM9606 rigid:JODsASHB53LJJClfTrNPgI4uEa4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UGJ1 uniprotkb:Q3SY69 intact:EBI-1052544|uniprotkb:Q969X3|uniprotkb:Q9NVF0|uniprotkb:B3KNK6|ensembl:ENSP00000260383 intact:EBI-6916128|ensembl:ENSP00000258494|uniprotkb:Q3SY68|uniprotkb:Q68D62|uniprotkb:Q6AI55|uniprotkb:Q8N922 psi-mi:gcp4_human(display_long)|uniprotkb:Gamma-ring complex protein 76 kDa(gene name synonym)|uniprotkb:TUBGCP4(gene name)|psi-mi:TUBGCP4(display_short)|uniprotkb:76P(gene name synonym)|uniprotkb:GCP4(gene name synonym) psi-mi:al1l2_human(display_long)|uniprotkb:ALDH1L2(gene name)|psi-mi:ALDH1L2(display_short)|uniprotkb:Aldehyde dehydrogenase family 1 member L2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486484|imex:IM-26985-295 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055259.2|refseq:NP_001273343.1|refseq:XP_011519757.1|ensembl:ENSG00000137822(gene)|ensembl:ENST00000260383(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0055037"(recycling endosome)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|interpro:IPR042241|mint:Q9UGJ1|rcsb pdb:3RIP|rcsb pdb:6V69|rcsb pdb:6V6S|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320|dip:DIP-50536N refseq:XP_011536291.1|ensembl:ENST00000258494(transcript)|go:"GO:0004029"("aldehyde dehydrogenase (NAD+) activity")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006730"(one-carbon metabolic process)|go:"GO:0009058"(biosynthetic process)|go:"GO:0009258"(10-formyltetrahydrofolate catabolic process)|go:"GO:0016155"(formyltetrahydrofolate dehydrogenase activity)|go:"GO:0016742"(hydroxymethyl-, formyl- and related transferase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001555(Phosphoribosylglycinamide formyltransferase, active site)|interpro:IPR002376(Formyl transferase, N-terminal)|interpro:IPR005793(Formyl transferase, C-terminal)|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR011034(Formyl transferase, C-terminal-like)|interpro:IPR011407(10-formyltetrahydrofolate dehydrogenase)|interpro:IPR015590(Aldehyde dehydrogenase)|interpro:IPR016160(Aldehyde dehydrogenase, conserved site)|interpro:IPR016161(Aldehyde/histidinol dehydrogenase)|ensembl:ENSG00000136010(gene)|interpro:IPR016162(Aldehyde dehydrogenase, N-terminal)|interpro:IPR016163(Aldehyde dehydrogenase, C-terminal)|interpro:IPR029510|interpro:IPR036477|interpro:IPR036736|interpro:IPR037022|mint:Q3SY69|reactome:R-HSA-196757|refseq:NP_001029345.2 - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5pAlGB03qeX0CJ0etjcLInwgaZQ9606 rogid:Tfg9TJwXfyRvVxezABcOGaJrcas9606 rigid:JODsASHB53LJJClfTrNPgI4uEa4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UGJ1 uniprotkb:Q8NBQ5 intact:EBI-1052544|uniprotkb:Q969X3|uniprotkb:Q9NVF0|uniprotkb:B3KNK6|ensembl:ENSP00000260383 intact:EBI-1052304|uniprotkb:Q96HF6|uniprotkb:Q9UKU4|ensembl:ENSP00000351035 psi-mi:gcp4_human(display_long)|uniprotkb:Gamma-ring complex protein 76 kDa(gene name synonym)|uniprotkb:TUBGCP4(gene name)|psi-mi:TUBGCP4(display_short)|uniprotkb:76P(gene name synonym)|uniprotkb:GCP4(gene name synonym) psi-mi:dhb11_human(display_long)|uniprotkb:17-beta-hydroxysteroid dehydrogenase 11(gene name synonym)|uniprotkb:17-beta-hydroxysteroid dehydrogenase XI(gene name synonym)|uniprotkb:Dehydrogenase/reductase SDR family member 8(gene name synonym)|uniprotkb:Retinal short-chain dehydrogenase/reductase 2(gene name synonym)|uniprotkb:Cutaneous T-cell lymphoma-associated antigen HD-CL-03(gene name synonym)|uniprotkb:HSD17B11(gene name)|psi-mi:HSD17B11(display_short)|uniprotkb:DHRS8(gene name synonym)|uniprotkb:PAN1B(gene name synonym)|uniprotkb:SDR16C2(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 16C member 2(gene name synonym)|uniprotkb:PSEC0029(orf name)|uniprotkb:UNQ207/PRO233(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486484|imex:IM-26985-295 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055259.2|refseq:NP_001273343.1|refseq:XP_011519757.1|ensembl:ENSG00000137822(gene)|ensembl:ENST00000260383(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0055037"(recycling endosome)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|interpro:IPR042241|mint:Q9UGJ1|rcsb pdb:3RIP|rcsb pdb:6V69|rcsb pdb:6V6S|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320|dip:DIP-50536N refseq:NP_057329.3|ensembl:ENSG00000198189(gene)|ensembl:ENST00000358290(transcript)|go:"GO:0004303"(estradiol 17-beta-dehydrogenase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006703"(estrogen biosynthetic process)|go:"GO:0006710"(androgen catabolic process)|go:"GO:0016229"(steroid dehydrogenase activity)|go:"GO:0016616"(oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor)|go:"GO:0044594"("17-beta-hydroxysteroid dehydrogenase (NAD+) activity")|go:"GO:0072582"("17-beta-hydroxysteroid dehydrogenase (NADP+) activity")|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR036291|mint:Q8NBQ5|rcsb pdb:1YB1|reactome:R-HSA-193144 - - comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5pAlGB03qeX0CJ0etjcLInwgaZQ9606 rogid:jWhP4Y15W31yQ1WiYLQ5NRK6bYw9606 rigid:JODsASHB53LJJClfTrNPgI4uEa4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UGJ1 uniprotkb:Q13724 intact:EBI-1052544|uniprotkb:Q969X3|uniprotkb:Q9NVF0|uniprotkb:B3KNK6|ensembl:ENSP00000260383 intact:EBI-720141|uniprotkb:Q17RN9|uniprotkb:Q8TCT5|uniprotkb:A8K938|ensembl:ENSP00000410992|uniprotkb:F5H6D0 psi-mi:gcp4_human(display_long)|uniprotkb:Gamma-ring complex protein 76 kDa(gene name synonym)|uniprotkb:TUBGCP4(gene name)|psi-mi:TUBGCP4(display_short)|uniprotkb:76P(gene name synonym)|uniprotkb:GCP4(gene name synonym) psi-mi:mogs_human(display_long)|uniprotkb:Processing A-glucosidase I(gene name synonym)|uniprotkb:MOGS(gene name)|psi-mi:MOGS(display_short)|uniprotkb:GCS1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486484|imex:IM-26985-295 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055259.2|refseq:NP_001273343.1|refseq:XP_011519757.1|ensembl:ENSG00000137822(gene)|ensembl:ENST00000260383(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0055037"(recycling endosome)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|interpro:IPR042241|mint:Q9UGJ1|rcsb pdb:3RIP|rcsb pdb:6V69|rcsb pdb:6V6S|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320|dip:DIP-50536N refseq:NP_001139630.1|refseq:NP_006293.2|ensembl:ENSG00000115275(gene)|ensembl:ENST00000448666(transcript)|go:"GO:0004573"(Glc3Man9GlcNAc2 oligosaccharide glucosidase activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006457"(protein folding)|go:"GO:0006487"(protein N-linked glycosylation)|go:"GO:0009311"(oligosaccharide metabolic process)|go:"GO:0015926"(glucosidase activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019082"(viral protein processing)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004888(Glycoside hydrolase, family 63)|interpro:IPR008928(Six-hairpin glycosidase-like)|interpro:IPR012341(Six-hairpin glycosidase)|interpro:IPR031335|interpro:IPR031631|interpro:IPR038518|mint:Q13724|reactome:R-HSA-4793954|reactome:R-HSA-532668|reactome:R-HSA-9683686|reactome:R-HSA-9694548 - - comment:"author score: 28" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5pAlGB03qeX0CJ0etjcLInwgaZQ9606 rogid:odbL3NUcP483ilKg/CMVn2GtdVs9606 rigid:JODsASHB53LJJClfTrNPgI4uEa4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UGJ1 uniprotkb:Q99720 intact:EBI-1052544|uniprotkb:Q969X3|uniprotkb:Q9NVF0|uniprotkb:B3KNK6|ensembl:ENSP00000260383 intact:EBI-3248663|ensembl:ENSP00000277010|uniprotkb:O00673|uniprotkb:Q2TSD1|uniprotkb:Q7Z653|uniprotkb:Q153Z1|uniprotkb:Q53GN2|uniprotkb:Q9NYX0|uniprotkb:O00725|uniprotkb:Q8N7H3|uniprotkb:Q0Z9W6|uniprotkb:D3DRM7 psi-mi:gcp4_human(display_long)|uniprotkb:Gamma-ring complex protein 76 kDa(gene name synonym)|uniprotkb:TUBGCP4(gene name)|psi-mi:TUBGCP4(display_short)|uniprotkb:76P(gene name synonym)|uniprotkb:GCP4(gene name synonym) psi-mi:sgmr1_human(display_long)|uniprotkb:SIGMAR1(gene name)|psi-mi:SIGMAR1(display_short)|uniprotkb:OPRS1(gene name synonym)|uniprotkb:SRBP(gene name synonym)|uniprotkb:Aging-associated gene 8 protein(gene name synonym)|uniprotkb:SR31747-binding protein(gene name synonym)|uniprotkb:Sigma 1-type opioid receptor(gene name synonym)|uniprotkb:AAG8(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486484|imex:IM-26985-295 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055259.2|refseq:NP_001273343.1|refseq:XP_011519757.1|ensembl:ENSG00000137822(gene)|ensembl:ENST00000260383(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0055037"(recycling endosome)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|interpro:IPR042241|mint:Q9UGJ1|rcsb pdb:3RIP|rcsb pdb:6V69|rcsb pdb:6V6S|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320|dip:DIP-50536N ensembl:ENSG00000147955(gene)|ensembl:ENST00000277010(transcript)|go:"GO:0004985"(G protein-coupled opioid receptor activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0006869"(lipid transport)|go:"GO:0007399"(nervous system development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016020"(membrane)|go:"GO:0030426"(growth cone)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0036474"(cell death in response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0098839"(postsynaptic density membrane)|interpro:IPR006716(ERG2 and sigma1 receptor-like)|mint:Q99720|rcsb pdb:5HK1|rcsb pdb:5HK2|rcsb pdb:6DJZ|rcsb pdb:6DK0|rcsb pdb:6DK1|reactome:R-HSA-9679191|refseq:NP_005857.1|refseq:NP_671513.1|refseq:NP_001269134.1|refseq:NP_001269135.1|refseq:NP_001269136.1|refseq:NP_001269137.1|refseq:NP_001269138.1|dip:DIP-61974N - - comment:"author score: 29" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5pAlGB03qeX0CJ0etjcLInwgaZQ9606 rogid:iEc1O6PXikkaE/0zk0A5Z7fMIZ49606 rigid:JODsASHB53LJJClfTrNPgI4uEa4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9UGJ1 uniprotkb:O75964 intact:EBI-1052544|uniprotkb:Q969X3|uniprotkb:Q9NVF0|uniprotkb:B3KNK6|ensembl:ENSP00000260383 intact:EBI-1044001|uniprotkb:Q96BV6|uniprotkb:Q9UBZ7|ensembl:ENSP00000300688|uniprotkb:A8K0K3 psi-mi:gcp4_human(display_long)|uniprotkb:Gamma-ring complex protein 76 kDa(gene name synonym)|uniprotkb:TUBGCP4(gene name)|psi-mi:TUBGCP4(display_short)|uniprotkb:76P(gene name synonym)|uniprotkb:GCP4(gene name synonym) psi-mi:atp5l_human(display_long)|uniprotkb:ATP5MG(gene name)|psi-mi:ATP5MG(display_short)|uniprotkb:ATP synthase membrane subunit g(gene name synonym)|uniprotkb:ATP5L(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486484|imex:IM-26985-295 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_055259.2|refseq:NP_001273343.1|refseq:XP_011519757.1|ensembl:ENSG00000137822(gene)|ensembl:ENST00000260383(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000922"(spindle pole)|go:"GO:0000923"(equatorial microtubule organizing center)|go:"GO:0000930"(gamma-tubulin complex)|go:"GO:0000931"(gamma-tubulin large complex)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0055037"(recycling endosome)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR007259(Spc97/Spc98)|interpro:IPR040457|interpro:IPR041470|interpro:IPR042241|mint:Q9UGJ1|rcsb pdb:3RIP|rcsb pdb:6V69|rcsb pdb:6V6S|rcsb pdb:7AS4|reactome:R-HSA-380270|reactome:R-HSA-380320|dip:DIP-50536N refseq:NP_006467.4|ensembl:ENSG00000167283(gene)|ensembl:ENST00000300688(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport)|interpro:IPR006808(ATPase, F0 complex, subunit G, mitochondrial)|interpro:IPR016702(Mitochondrial ATP synthase subunit g, animal)|mint:O75964|reactome:R-HSA-163210|reactome:R-HSA-8949613 - - comment:"author score: 52" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:5pAlGB03qeX0CJ0etjcLInwgaZQ9606 rogid:mn5/fFqk4xCCHb/MEuLAi5/lqmI9606 rigid:JODsASHB53LJJClfTrNPgI4uEa4 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P67809 uniprotkb:Q7Z6M2 intact:EBI-354065|uniprotkb:P16990|uniprotkb:P16991|uniprotkb:Q14972|uniprotkb:Q15325|uniprotkb:Q5FVF0|ensembl:ENSP00000361626 intact:EBI-8555452|intact:MINT-2831379|uniprotkb:Q86TR2|uniprotkb:Q6PIR2|uniprotkb:Q86YE0|ensembl:ENSP00000298097 psi-mi:ybox1_human(display_long)|uniprotkb:YBX1(gene name)|psi-mi:YBX1(display_short)|uniprotkb:YB1(gene name synonym)|uniprotkb:NSEP1(gene name synonym)|uniprotkb:Y-box transcription factor(gene name synonym)|uniprotkb:CCAAT-binding transcription factor I subunit A(gene name synonym)|uniprotkb:Enhancer factor I subunit A(gene name synonym)|uniprotkb:DNA-binding protein B(gene name synonym)|uniprotkb:Nuclease-sensitive element-binding protein 1(gene name synonym) psi-mi:fbx33_human(display_long)|uniprotkb:FBXO33(gene name)|psi-mi:FBXO33(display_short)|uniprotkb:FBX33(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486958|imex:IM-26985-457 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004550.2|dip:DIP-29405N|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990428"(miRNA transport)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P67809|rcsb pdb:1H95|rcsb pdb:5YTS|rcsb pdb:5YTT|rcsb pdb:5YTV|rcsb pdb:5YTX|rcsb pdb:6A6L|rcsb pdb:6KTC|rcsb pdb:6KUG|rcsb pdb:6LMR|rcsb pdb:6LMS|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-9017802|ensembl:ENSG00000065978(gene)|ensembl:ENST00000321358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0008544"(epidermis development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035198"(miRNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050658"(RNA transport)|go:"GO:0051020"(GTPase binding)|go:"GO:0051031"(tRNA transport)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding) refseq:NP_976046.1|ensembl:ENSG00000165355(gene)|ensembl:ENST00000298097(transcript)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0019005"(SCF ubiquitin ligase complex)|go:"GO:0031146"(SCF-dependent proteasomal ubiquitin-dependent protein catabolic process)|interpro:IPR001810(Cyclin-like F-box)|interpro:IPR032675|interpro:IPR036047|interpro:IPR039940|mint:Q7Z6M2 - - function:"Substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. Recognizes YBX1"|comment:mint|comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:0/mAXOzokPlDByFFzGTP8bp9nqo9606 rogid:xghq3It9yrnTgJaIqLJgHK+Y4ME9606 rigid:rADPW9J3Z/NJfzBCP2cEpYNLD9Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P67809 uniprotkb:Q9NRX2 intact:EBI-354065|uniprotkb:P16990|uniprotkb:P16991|uniprotkb:Q14972|uniprotkb:Q15325|uniprotkb:Q5FVF0|ensembl:ENSP00000361626 intact:EBI-7825154|ensembl:ENSP00000288937|uniprotkb:Q6IAH8|uniprotkb:Q9C066|uniprotkb:Q96Q53|uniprotkb:D3DQU3|intact:MINT-3064942 psi-mi:ybox1_human(display_long)|uniprotkb:YBX1(gene name)|psi-mi:YBX1(display_short)|uniprotkb:YB1(gene name synonym)|uniprotkb:NSEP1(gene name synonym)|uniprotkb:Y-box transcription factor(gene name synonym)|uniprotkb:CCAAT-binding transcription factor I subunit A(gene name synonym)|uniprotkb:Enhancer factor I subunit A(gene name synonym)|uniprotkb:DNA-binding protein B(gene name synonym)|uniprotkb:Nuclease-sensitive element-binding protein 1(gene name synonym) psi-mi:rm17_human(display_long)|uniprotkb:Mitochondrial large ribosomal subunit protein bL17m(gene name synonym)|uniprotkb:MRPL17(gene name)|psi-mi:MRPL17(display_short)|uniprotkb:LIP2(gene name synonym)|uniprotkb:LYST-interacting protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486958|imex:IM-26985-457 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004550.2|dip:DIP-29405N|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990428"(miRNA transport)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P67809|rcsb pdb:1H95|rcsb pdb:5YTS|rcsb pdb:5YTT|rcsb pdb:5YTV|rcsb pdb:5YTX|rcsb pdb:6A6L|rcsb pdb:6KTC|rcsb pdb:6KUG|rcsb pdb:6LMR|rcsb pdb:6LMS|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-9017802|ensembl:ENSG00000065978(gene)|ensembl:ENST00000321358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0008544"(epidermis development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035198"(miRNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050658"(RNA transport)|go:"GO:0051020"(GTPase binding)|go:"GO:0051031"(tRNA transport)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding) ensembl:ENSG00000158042(gene)|ensembl:ENST00000288937(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0019904"(protein domain specific binding)|interpro:IPR000456(Ribosomal protein L17)|interpro:IPR036373|mint:Q9NRX2|rcsb pdb:2CQM|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:7OF7|refseq:NP_071344.1 - - comment:mint|comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:0/mAXOzokPlDByFFzGTP8bp9nqo9606 rogid:9IL43XtZbhcbaI7Gkq3X6O1M3XE9606 rigid:rADPW9J3Z/NJfzBCP2cEpYNLD9Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P67809 uniprotkb:Q13242 intact:EBI-354065|uniprotkb:P16990|uniprotkb:P16991|uniprotkb:Q14972|uniprotkb:Q15325|uniprotkb:Q5FVF0|ensembl:ENSP00000361626 intact:EBI-2949710|ensembl:ENSP00000229390|uniprotkb:Q52LD1 psi-mi:ybox1_human(display_long)|uniprotkb:YBX1(gene name)|psi-mi:YBX1(display_short)|uniprotkb:YB1(gene name synonym)|uniprotkb:NSEP1(gene name synonym)|uniprotkb:Y-box transcription factor(gene name synonym)|uniprotkb:CCAAT-binding transcription factor I subunit A(gene name synonym)|uniprotkb:Enhancer factor I subunit A(gene name synonym)|uniprotkb:DNA-binding protein B(gene name synonym)|uniprotkb:Nuclease-sensitive element-binding protein 1(gene name synonym) psi-mi:srsf9_human(display_long)|uniprotkb:SRSF9(gene name)|psi-mi:SRSF9(display_short)|uniprotkb:SFRS9(gene name synonym)|uniprotkb:SRP30C(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SRp30C(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 9(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486958|imex:IM-26985-457 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004550.2|dip:DIP-29405N|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990428"(miRNA transport)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P67809|rcsb pdb:1H95|rcsb pdb:5YTS|rcsb pdb:5YTT|rcsb pdb:5YTV|rcsb pdb:5YTX|rcsb pdb:6A6L|rcsb pdb:6KTC|rcsb pdb:6KUG|rcsb pdb:6LMR|rcsb pdb:6LMS|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-9017802|ensembl:ENSG00000065978(gene)|ensembl:ENST00000321358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0008544"(epidermis development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035198"(miRNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050658"(RNA transport)|go:"GO:0051020"(GTPase binding)|go:"GO:0051031"(tRNA transport)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding) go:"GO:0006397"(mRNA processing)|go:"GO:0009636"(response to toxic substance)|go:"GO:0016607"(nuclear speck)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0043279"(response to alkaloid)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|go:"GO:0006376"(mRNA splice site selection)|interpro:IPR034503|interpro:IPR034995|interpro:IPR035979|mint:Q13242|reactome:R-HSA-159236|reactome:R-HSA-72163|reactome:R-HSA-72187|reactome:R-HSA-73856|ensembl:ENSG00000111786(gene)|ensembl:ENST00000229390(transcript)|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|refseq:NP_003760.1|dip:DIP-40741N - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:0/mAXOzokPlDByFFzGTP8bp9nqo9606 rogid:9x6TWFk1zN1YodjXBiwi/MtNJe49606 rigid:rADPW9J3Z/NJfzBCP2cEpYNLD9Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P67809 uniprotkb:Q8TCC3 intact:EBI-354065|uniprotkb:P16990|uniprotkb:P16991|uniprotkb:Q14972|uniprotkb:Q15325|uniprotkb:Q5FVF0|ensembl:ENSP00000361626 intact:EBI-11038252|uniprotkb:Q9P0N0|uniprotkb:A6NIC6|uniprotkb:D3DVI0|uniprotkb:Q0D2Q7|uniprotkb:Q6ZTP4|uniprotkb:Q96Q69|uniprotkb:D3DVI3|ensembl:ENSP00000338057|ensembl:ENSP00000386752 psi-mi:ybox1_human(display_long)|uniprotkb:YBX1(gene name)|psi-mi:YBX1(display_short)|uniprotkb:YB1(gene name synonym)|uniprotkb:NSEP1(gene name synonym)|uniprotkb:Y-box transcription factor(gene name synonym)|uniprotkb:CCAAT-binding transcription factor I subunit A(gene name synonym)|uniprotkb:Enhancer factor I subunit A(gene name synonym)|uniprotkb:DNA-binding protein B(gene name synonym)|uniprotkb:Nuclease-sensitive element-binding protein 1(gene name synonym) psi-mi:rm30_human(display_long)|uniprotkb:MRPL30(gene name)|psi-mi:MRPL30(display_short)|uniprotkb:39S ribosomal protein L28, mitochondrial(gene name synonym)|uniprotkb:MRPL28(gene name synonym)|uniprotkb:RPML28(gene name synonym)|uniprotkb:HSPC249(orf name)|uniprotkb:Mitochondrial large ribosomal subunit protein uL30m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486958|imex:IM-26985-457 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004550.2|dip:DIP-29405N|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990428"(miRNA transport)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P67809|rcsb pdb:1H95|rcsb pdb:5YTS|rcsb pdb:5YTT|rcsb pdb:5YTV|rcsb pdb:5YTX|rcsb pdb:6A6L|rcsb pdb:6KTC|rcsb pdb:6KUG|rcsb pdb:6LMR|rcsb pdb:6LMS|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-9017802|ensembl:ENSG00000065978(gene)|ensembl:ENST00000321358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0008544"(epidermis development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035198"(miRNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050658"(RNA transport)|go:"GO:0051020"(GTPase binding)|go:"GO:0051031"(tRNA transport)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding) refseq:NP_660213.1|interpro:IPR036919|mint:Q8TCC3|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|interpro:IPR016082(Ribosomal protein L30, C-terminal)|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|ensembl:ENSG00000185414(gene)|ensembl:ENST00000338148(transcript)|ensembl:ENST00000409841(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|interpro:IPR005996(Ribosomal protein L30, bacterial-type) - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:0/mAXOzokPlDByFFzGTP8bp9nqo9606 rogid:B9fWF4LjIKSO3Cg2+oLuH2KQjfE9606 rigid:rADPW9J3Z/NJfzBCP2cEpYNLD9Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P67809 uniprotkb:P11940 intact:EBI-354065|uniprotkb:P16990|uniprotkb:P16991|uniprotkb:Q14972|uniprotkb:Q15325|uniprotkb:Q5FVF0|ensembl:ENSP00000361626 intact:EBI-81531|intact:EBI-28983164|ensembl:ENSP00000313007|ensembl:ENSP00000428749|ensembl:ENSP00000428840|ensembl:ENSP00000429119|ensembl:ENSP00000429790|ensembl:ENSP00000429892|ensembl:ENSP00000430012|uniprotkb:Q15097|uniprotkb:Q93004 psi-mi:ybox1_human(display_long)|uniprotkb:YBX1(gene name)|psi-mi:YBX1(display_short)|uniprotkb:YB1(gene name synonym)|uniprotkb:NSEP1(gene name synonym)|uniprotkb:Y-box transcription factor(gene name synonym)|uniprotkb:CCAAT-binding transcription factor I subunit A(gene name synonym)|uniprotkb:Enhancer factor I subunit A(gene name synonym)|uniprotkb:DNA-binding protein B(gene name synonym)|uniprotkb:Nuclease-sensitive element-binding protein 1(gene name synonym) psi-mi:pabp1_human(display_long)|uniprotkb:PABPC1(gene name)|psi-mi:PABPC1(display_short)|uniprotkb:PAB1(gene name synonym)|uniprotkb:PABP1(gene name synonym)|uniprotkb:PABPC2(gene name synonym)|uniprotkb:PABP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486958|imex:IM-26985-457 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004550.2|dip:DIP-29405N|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990428"(miRNA transport)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P67809|rcsb pdb:1H95|rcsb pdb:5YTS|rcsb pdb:5YTT|rcsb pdb:5YTV|rcsb pdb:5YTX|rcsb pdb:6A6L|rcsb pdb:6KTC|rcsb pdb:6KUG|rcsb pdb:6LMR|rcsb pdb:6LMS|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-9017802|ensembl:ENSG00000065978(gene)|ensembl:ENST00000321358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0008544"(epidermis development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035198"(miRNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050658"(RNA transport)|go:"GO:0051020"(GTPase binding)|go:"GO:0051031"(tRNA transport)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding) interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:P11940|rcsb pdb:1CVJ|rcsb pdb:1G9L|rcsb pdb:1JGN|rcsb pdb:1JH4|rcsb pdb:2K8G|rcsb pdb:2RQG|rcsb pdb:2RQH|rcsb pdb:2X04|rcsb pdb:3KTP|rcsb pdb:3KTR|rcsb pdb:3KUI|rcsb pdb:3KUJ|rcsb pdb:3KUR|rcsb pdb:3KUS|rcsb pdb:3KUT|rcsb pdb:3PKN|interpro:IPR003954(RNA recognition, region 1)|rcsb pdb:3PTH|rcsb pdb:4F02|rcsb pdb:4F25|rcsb pdb:4F26|ensembl:ENSG00000070756(gene)|ensembl:ENST00000318607(transcript)|ensembl:ENST00000520142(transcript)|ensembl:ENST00000520804(transcript)|ensembl:ENST00000521865(transcript)|ensembl:ENST00000522658(transcript)|ensembl:ENST00000522720(transcript)|ensembl:ENST00000523555(transcript)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0005634"(nucleus)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0031252"(cell leading edge)|go:"GO:0005737"(cytoplasm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008143"("poly(A) binding")|go:"GO:0048255"(mRNA stabilization)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008494"(translation activator activity)|go:"GO:0060213"("positive regulation of nuclear-transcribed mRNA poly(A) tail shortening")|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1900153"(positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000623"(negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|rcsb pdb:5DX1|refseq:NP_002559.2|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5LGP|rcsb pdb:5LGQ|rcsb pdb:5LGR|rcsb pdb:5LGS|reactome:R-HSA-156827|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSP00000313007|ensembl:ENSP00000430012|ensembl:ENSP00000428749|ensembl:ENSP00000429119|ensembl:ENSP00000428840|ensembl:ENSP00000429790|ensembl:ENSP00000429892|refseq:XP_005250918.1|dip:DIP-31613N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:0/mAXOzokPlDByFFzGTP8bp9nqo9606 rogid:XudTSPq2h9ckKAc48X88RVafPRU9606 rigid:rADPW9J3Z/NJfzBCP2cEpYNLD9Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P67809 uniprotkb:P49406 intact:EBI-354065|uniprotkb:P16990|uniprotkb:P16991|uniprotkb:Q14972|uniprotkb:Q15325|uniprotkb:Q5FVF0|ensembl:ENSP00000361626 intact:EBI-1188518|uniprotkb:Q96Q52|uniprotkb:Q53TX9|ensembl:ENSP00000377486|ensembl:ENSP00000387284 psi-mi:ybox1_human(display_long)|uniprotkb:YBX1(gene name)|psi-mi:YBX1(display_short)|uniprotkb:YB1(gene name synonym)|uniprotkb:NSEP1(gene name synonym)|uniprotkb:Y-box transcription factor(gene name synonym)|uniprotkb:CCAAT-binding transcription factor I subunit A(gene name synonym)|uniprotkb:Enhancer factor I subunit A(gene name synonym)|uniprotkb:DNA-binding protein B(gene name synonym)|uniprotkb:Nuclease-sensitive element-binding protein 1(gene name synonym) psi-mi:rm19_human(display_long)|uniprotkb:MRPL15(gene name synonym)|uniprotkb:39S ribosomal protein L15, mitochondrial(gene name synonym)|uniprotkb:MRPL19(gene name)|psi-mi:MRPL19(display_short)|uniprotkb:KIAA0104(gene name synonym)|uniprotkb:Mitochondrial large ribosomal subunit protein bL19m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486958|imex:IM-26985-457 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004550.2|dip:DIP-29405N|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990428"(miRNA transport)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P67809|rcsb pdb:1H95|rcsb pdb:5YTS|rcsb pdb:5YTT|rcsb pdb:5YTV|rcsb pdb:5YTX|rcsb pdb:6A6L|rcsb pdb:6KTC|rcsb pdb:6KUG|rcsb pdb:6LMR|rcsb pdb:6LMS|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-9017802|ensembl:ENSG00000065978(gene)|ensembl:ENST00000321358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0008544"(epidermis development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035198"(miRNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050658"(RNA transport)|go:"GO:0051020"(GTPase binding)|go:"GO:0051031"(tRNA transport)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding) refseq:NP_055578.2|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:7O9M|ensembl:ENSG00000115364(gene)|ensembl:ENST00000393909(transcript)|ensembl:ENST00000409374(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|interpro:IPR001857(Ribosomal protein L19)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR038657|mint:P49406|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:0/mAXOzokPlDByFFzGTP8bp9nqo9606 rogid:4ZCZpq3u9wkdpuNVFpk+bhceaW09606 rigid:rADPW9J3Z/NJfzBCP2cEpYNLD9Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P67809 uniprotkb:P05455 intact:EBI-354065|uniprotkb:P16990|uniprotkb:P16991|uniprotkb:Q14972|uniprotkb:Q15325|uniprotkb:Q5FVF0|ensembl:ENSP00000361626 intact:EBI-358037|ensembl:ENSP00000260956|ensembl:ENSP00000386636|uniprotkb:Q15367|uniprotkb:Q53XJ4 psi-mi:ybox1_human(display_long)|uniprotkb:YBX1(gene name)|psi-mi:YBX1(display_short)|uniprotkb:YB1(gene name synonym)|uniprotkb:NSEP1(gene name synonym)|uniprotkb:Y-box transcription factor(gene name synonym)|uniprotkb:CCAAT-binding transcription factor I subunit A(gene name synonym)|uniprotkb:Enhancer factor I subunit A(gene name synonym)|uniprotkb:DNA-binding protein B(gene name synonym)|uniprotkb:Nuclease-sensitive element-binding protein 1(gene name synonym) psi-mi:la_human(display_long)|uniprotkb:SSB(gene name)|psi-mi:SSB(display_short)|uniprotkb:Sjoegren syndrome type B antigen(gene name synonym)|uniprotkb:La ribonucleoprotein(gene name synonym)|uniprotkb:La autoantigen(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486958|imex:IM-26985-457 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004550.2|dip:DIP-29405N|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990428"(miRNA transport)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P67809|rcsb pdb:1H95|rcsb pdb:5YTS|rcsb pdb:5YTT|rcsb pdb:5YTV|rcsb pdb:5YTX|rcsb pdb:6A6L|rcsb pdb:6KTC|rcsb pdb:6KUG|rcsb pdb:6LMR|rcsb pdb:6LMS|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-9017802|ensembl:ENSG00000065978(gene)|ensembl:ENST00000321358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0008544"(epidermis development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035198"(miRNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050658"(RNA transport)|go:"GO:0051020"(GTPase binding)|go:"GO:0051031"(tRNA transport)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding) refseq:NP_003133.1|ensembl:ENSG00000138385(gene)|ensembl:ENST00000260956(transcript)|ensembl:ENST00000409333(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006400"(tRNA modification)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0008033"(tRNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008334"(histone mRNA metabolic process)|go:"GO:0042780"(tRNA 3'-end processing)|go:"GO:0071045"(nuclear histone mRNA catabolic process)|refseq:NP_001281074.1|dip:DIP-29750N|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002344(Lupus La protein)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR014886(RNA binding motif)|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|mint:P05455|rcsb pdb:1OWX|rcsb pdb:1S79|rcsb pdb:1S7A|rcsb pdb:1YTY|rcsb pdb:1ZH5|rcsb pdb:2VOD|rcsb pdb:2VON|rcsb pdb:2VOO|rcsb pdb:2VOP|reactome:R-HSA-73980|reactome:R-HSA-749476 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:0/mAXOzokPlDByFFzGTP8bp9nqo9606 rogid:Lgpr3jgLWGk3AZzPwjB1swJRsoQ9606 rigid:rADPW9J3Z/NJfzBCP2cEpYNLD9Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P67809 uniprotkb:Q9H0U6 intact:EBI-354065|uniprotkb:P16990|uniprotkb:P16991|uniprotkb:Q14972|uniprotkb:Q15325|uniprotkb:Q5FVF0|ensembl:ENSP00000361626 intact:EBI-2560240|uniprotkb:Q5TAP9|uniprotkb:Q9NZW8|ensembl:ENSP00000356001 psi-mi:ybox1_human(display_long)|uniprotkb:YBX1(gene name)|psi-mi:YBX1(display_short)|uniprotkb:YB1(gene name synonym)|uniprotkb:NSEP1(gene name synonym)|uniprotkb:Y-box transcription factor(gene name synonym)|uniprotkb:CCAAT-binding transcription factor I subunit A(gene name synonym)|uniprotkb:Enhancer factor I subunit A(gene name synonym)|uniprotkb:DNA-binding protein B(gene name synonym)|uniprotkb:Nuclease-sensitive element-binding protein 1(gene name synonym) psi-mi:rm18_human(display_long)|uniprotkb:MRPL18(gene name)|psi-mi:MRPL18(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein uL18m(gene name synonym)|uniprotkb:HSPC071(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486958|imex:IM-26985-457 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004550.2|dip:DIP-29405N|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990428"(miRNA transport)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P67809|rcsb pdb:1H95|rcsb pdb:5YTS|rcsb pdb:5YTT|rcsb pdb:5YTV|rcsb pdb:5YTX|rcsb pdb:6A6L|rcsb pdb:6KTC|rcsb pdb:6KUG|rcsb pdb:6LMR|rcsb pdb:6LMS|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-9017802|ensembl:ENSG00000065978(gene)|ensembl:ENST00000321358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0008544"(epidermis development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035198"(miRNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050658"(RNA transport)|go:"GO:0051020"(GTPase binding)|go:"GO:0051031"(tRNA transport)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding) refseq:NP_054880.2|ensembl:ENSG00000112110(gene)|ensembl:ENST00000367034(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005615"(extracellular space)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0035928"(rRNA import into mitochondrion)|interpro:IPR005484(Ribosomal protein L18/L5)|interpro:IPR036967|mint:Q9H0U6|rcsb pdb:3J7Y|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:NP_001305746.1|dip:DIP-56844N - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:0/mAXOzokPlDByFFzGTP8bp9nqo9606 rogid:MtxdrTVdqAfWZqnuxD+PGs218/A9606 rigid:rADPW9J3Z/NJfzBCP2cEpYNLD9Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P67809 uniprotkb:Q13310 intact:EBI-354065|uniprotkb:P16990|uniprotkb:P16991|uniprotkb:Q14972|uniprotkb:Q15325|uniprotkb:Q5FVF0|ensembl:ENSP00000361626 intact:EBI-372844|uniprotkb:Q6P0N3|uniprotkb:B1ANQ8|ensembl:ENSP00000361948|intact:EBI-877641|uniprotkb:Q4VC03 psi-mi:ybox1_human(display_long)|uniprotkb:YBX1(gene name)|psi-mi:YBX1(display_short)|uniprotkb:YB1(gene name synonym)|uniprotkb:NSEP1(gene name synonym)|uniprotkb:Y-box transcription factor(gene name synonym)|uniprotkb:CCAAT-binding transcription factor I subunit A(gene name synonym)|uniprotkb:Enhancer factor I subunit A(gene name synonym)|uniprotkb:DNA-binding protein B(gene name synonym)|uniprotkb:Nuclease-sensitive element-binding protein 1(gene name synonym) psi-mi:pabp4_human(display_long)|uniprotkb:PABPC4(gene name)|psi-mi:PABPC4(display_short)|uniprotkb:APP1(gene name synonym)|uniprotkb:PABP4(gene name synonym)|uniprotkb:"Inducible poly(A)-binding protein"(gene name synonym)|uniprotkb:Activated-platelet protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486958|imex:IM-26985-457 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004550.2|dip:DIP-29405N|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990428"(miRNA transport)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P67809|rcsb pdb:1H95|rcsb pdb:5YTS|rcsb pdb:5YTT|rcsb pdb:5YTV|rcsb pdb:5YTX|rcsb pdb:6A6L|rcsb pdb:6KTC|rcsb pdb:6KUG|rcsb pdb:6LMR|rcsb pdb:6LMS|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-9017802|ensembl:ENSG00000065978(gene)|ensembl:ENST00000321358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0008544"(epidermis development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035198"(miRNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050658"(RNA transport)|go:"GO:0051020"(GTPase binding)|go:"GO:0051031"(tRNA transport)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding) refseq:NP_001129126.1|refseq:NP_003810.1|ensembl:ENSG00000090621(gene)|ensembl:ENST00000372857(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006396"(RNA processing)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0006412"(translation)|go:"GO:0007596"(blood coagulation)|go:"GO:0008143"("poly(A) binding")|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0061515"(myeloid cell development)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002004(Polyadenylate-binding protein/Hyperplastic disc protein)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006515(Polyadenylate binding protein, human types 1, 2, 3, 4)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|interpro:IPR036053|mint:Q13310|refseq:NP_001129125.1 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:0/mAXOzokPlDByFFzGTP8bp9nqo9606 rogid:u1qCM3o5X7jLIa1vyqFCIH7v01w9606 rigid:rADPW9J3Z/NJfzBCP2cEpYNLD9Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P67809 uniprotkb:Q9NX24 intact:EBI-354065|uniprotkb:P16990|uniprotkb:P16991|uniprotkb:Q14972|uniprotkb:Q15325|uniprotkb:Q5FVF0|ensembl:ENSP00000361626 intact:EBI-1050064|uniprotkb:Q9P095|uniprotkb:A6NKY8|intact:EBI-5774108|ensembl:ENSP00000274606 psi-mi:ybox1_human(display_long)|uniprotkb:YBX1(gene name)|psi-mi:YBX1(display_short)|uniprotkb:YB1(gene name synonym)|uniprotkb:NSEP1(gene name synonym)|uniprotkb:Y-box transcription factor(gene name synonym)|uniprotkb:CCAAT-binding transcription factor I subunit A(gene name synonym)|uniprotkb:Enhancer factor I subunit A(gene name synonym)|uniprotkb:DNA-binding protein B(gene name synonym)|uniprotkb:Nuclease-sensitive element-binding protein 1(gene name synonym) psi-mi:nhp2_human(display_long)|uniprotkb:Nucleolar protein family A member 2(gene name synonym)|uniprotkb:snoRNP protein NHP2(gene name synonym)|uniprotkb:NHP2(gene name)|psi-mi:NHP2(display_short)|uniprotkb:NOLA2(gene name synonym)|uniprotkb:HSPC286(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486958|imex:IM-26985-457 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004550.2|dip:DIP-29405N|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990428"(miRNA transport)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P67809|rcsb pdb:1H95|rcsb pdb:5YTS|rcsb pdb:5YTT|rcsb pdb:5YTV|rcsb pdb:5YTX|rcsb pdb:6A6L|rcsb pdb:6KTC|rcsb pdb:6KUG|rcsb pdb:6LMR|rcsb pdb:6LMS|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-9017802|ensembl:ENSG00000065978(gene)|ensembl:ENST00000321358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0008544"(epidermis development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035198"(miRNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050658"(RNA transport)|go:"GO:0051020"(GTPase binding)|go:"GO:0051031"(tRNA transport)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding) refseq:NP_060308.1|refseq:NP_001030005.1|ensembl:ENSG00000145912(gene)|ensembl:ENST00000274606(transcript)|go:"GO:0000469"(cleavage involved in rRNA processing)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005732"("sno(s)RNA-containing ribonucleoprotein complex")|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0031118"(rRNA pseudouridine synthesis)|go:"GO:0031120"(snRNA pseudouridine synthesis)|go:"GO:0031429"(box H/ACA snoRNP complex)|go:"GO:0034513"(box H/ACA snoRNA binding)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0072589"(box H/ACA scaRNP complex)|go:"GO:0090661"(box H/ACA telomerase RNP complex)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002415(High mobility group-like nuclear protein)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|mint:Q9NX24|rcsb pdb:7BGB|reactome:R-HSA-171319|reactome:R-HSA-6790901 - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:0/mAXOzokPlDByFFzGTP8bp9nqo9606 rogid:ZZchZSzrw15BqMfddUMcaxZRF0w9606 rigid:rADPW9J3Z/NJfzBCP2cEpYNLD9Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P67809 uniprotkb:P62995 intact:EBI-354065|uniprotkb:P16990|uniprotkb:P16991|uniprotkb:Q14972|uniprotkb:Q15325|uniprotkb:Q5FVF0|ensembl:ENSP00000361626 intact:EBI-725485|uniprotkb:O15449|uniprotkb:Q15815|uniprotkb:Q64283|uniprotkb:B4DVK2|uniprotkb:D3DNU3|ensembl:ENSP00000416959 psi-mi:ybox1_human(display_long)|uniprotkb:YBX1(gene name)|psi-mi:YBX1(display_short)|uniprotkb:YB1(gene name synonym)|uniprotkb:NSEP1(gene name synonym)|uniprotkb:Y-box transcription factor(gene name synonym)|uniprotkb:CCAAT-binding transcription factor I subunit A(gene name synonym)|uniprotkb:Enhancer factor I subunit A(gene name synonym)|uniprotkb:DNA-binding protein B(gene name synonym)|uniprotkb:Nuclease-sensitive element-binding protein 1(gene name synonym) psi-mi:tra2b_human(display_long)|uniprotkb:TRA2B(gene name)|psi-mi:TRA2B(display_short)|uniprotkb:SFRS10(gene name synonym)|uniprotkb:Transformer-2 protein homolog B(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 10(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486958|imex:IM-26985-457 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004550.2|dip:DIP-29405N|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990428"(miRNA transport)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P67809|rcsb pdb:1H95|rcsb pdb:5YTS|rcsb pdb:5YTT|rcsb pdb:5YTV|rcsb pdb:5YTX|rcsb pdb:6A6L|rcsb pdb:6KTC|rcsb pdb:6KUG|rcsb pdb:6LMR|rcsb pdb:6LMS|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-9017802|ensembl:ENSG00000065978(gene)|ensembl:ENST00000321358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0008544"(epidermis development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035198"(miRNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050658"(RNA transport)|go:"GO:0051020"(GTPase binding)|go:"GO:0051031"(tRNA transport)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding) refseq:NP_004584.1|refseq:XP_005247760.1|refseq:NP_001230808.1|refseq:XP_011511374.1|ensembl:ENSG00000136527(gene)|ensembl:ENST00000453386(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:1990403"(embryonic brain development)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P62995|rcsb pdb:2CQC|rcsb pdb:2KXN|rcsb pdb:2RRA|rcsb pdb:2RRB|reactome:R-HSA-72163|reactome:R-HSA-9013418|reactome:R-HSA-9013422|refseq:XP_016862522.1|dip:DIP-42278N - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:0/mAXOzokPlDByFFzGTP8bp9nqo9606 rogid:6uZGeHEDlIVsb2uPeo+9NoR4tDw9606 rigid:rADPW9J3Z/NJfzBCP2cEpYNLD9Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P67809 uniprotkb:Q7Z2W9 intact:EBI-354065|uniprotkb:P16990|uniprotkb:P16991|uniprotkb:Q14972|uniprotkb:Q15325|uniprotkb:Q5FVF0|ensembl:ENSP00000361626 intact:EBI-6393520|ensembl:ENSP00000354580|uniprotkb:C9JPR2|uniprotkb:A6NKU0 psi-mi:ybox1_human(display_long)|uniprotkb:YBX1(gene name)|psi-mi:YBX1(display_short)|uniprotkb:YB1(gene name synonym)|uniprotkb:NSEP1(gene name synonym)|uniprotkb:Y-box transcription factor(gene name synonym)|uniprotkb:CCAAT-binding transcription factor I subunit A(gene name synonym)|uniprotkb:Enhancer factor I subunit A(gene name synonym)|uniprotkb:DNA-binding protein B(gene name synonym)|uniprotkb:Nuclease-sensitive element-binding protein 1(gene name synonym) psi-mi:rm21_human(display_long)|uniprotkb:MRPL21(gene name)|psi-mi:MRPL21(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein bL21m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486958|imex:IM-26985-457 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_004550.2|dip:DIP-29405N|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990428"(miRNA transport)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P67809|rcsb pdb:1H95|rcsb pdb:5YTS|rcsb pdb:5YTT|rcsb pdb:5YTV|rcsb pdb:5YTX|rcsb pdb:6A6L|rcsb pdb:6KTC|rcsb pdb:6KUG|rcsb pdb:6LMR|rcsb pdb:6LMS|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-9017802|ensembl:ENSG00000065978(gene)|ensembl:ENST00000321358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0008544"(epidermis development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035198"(miRNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050658"(RNA transport)|go:"GO:0051020"(GTPase binding)|go:"GO:0051031"(tRNA transport)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding) ensembl:ENSG00000197345(gene)|ensembl:ENST00000362034(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|interpro:IPR001787(Ribosomal protein L21)|interpro:IPR028909|interpro:IPR036164|mint:Q7Z2W9|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|refseq:NP_852615.1|refseq:NP_852616.1 - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:0/mAXOzokPlDByFFzGTP8bp9nqo9606 rogid:AtmLgjvRKsb8i5m6dl41VwqA1+Q9606 rigid:rADPW9J3Z/NJfzBCP2cEpYNLD9Y false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P13010 uniprotkb:Q9HCY8 intact:EBI-357997|uniprotkb:A8K3X5|uniprotkb:Q0Z7V0|uniprotkb:Q53HH7|uniprotkb:Q7M4N0|uniprotkb:Q4VBQ5|uniprotkb:Q9UCQ0|uniprotkb:Q9UCQ1|ensembl:ENSP00000375977|ensembl:ENSP00000375978 intact:EBI-751842|uniprotkb:Q5RHT0|ensembl:ENSP00000340463|ensembl:ENSP00000357690|ensembl:ENSP00000357691|ensembl:ENSP00000420296 psi-mi:xrcc5_human(display_long)|uniprotkb:XRCC5(gene name)|psi-mi:XRCC5(display_short)|uniprotkb:G22P2(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 80 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p86(gene name synonym)|uniprotkb:86 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Ku86(gene name synonym)|uniprotkb:Ku80(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 85 kDa subunit(gene name synonym)|uniprotkb:Nuclear factor IV(gene name synonym)|uniprotkb:DNA repair protein XRCC5(gene name synonym)|uniprotkb:"X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)"(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 2(gene name synonym) psi-mi:s10ae_human(display_long)|uniprotkb:S100 calcium-binding protein A14(gene name synonym)|uniprotkb:S100A14(gene name)|psi-mi:S100A14(display_short)|uniprotkb:S100A15(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486946|imex:IM-26985-299 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066964.1|ensembl:ENST00000392132(transcript)|ensembl:ENSG00000079246(gene)|dip:DIP-31379N|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045027"(DNA end binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0090734"(site of DNA damage)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|ensembl:ENST00000392133(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008047"(enzyme activator activity)|go:"GO:1904430"(negative regulation of t-circle formation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR014893(Ku, C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR024193|interpro:IPR036465|interpro:IPR036494|mint:P13010|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1Q2Z|rcsb pdb:1RW2|rcsb pdb:3RZ9|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZH6|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7AXZ|rcsb pdb:7K0Y|rcsb pdb:7K17|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695 refseq:NP_065723.1|refseq:XP_005245419.1|refseq:XP_016857364.1|ensembl:ENSG00000189334(gene)|ensembl:ENST00000344616(transcript)|ensembl:ENST00000368701(transcript)|ensembl:ENST00000368702(transcript)|ensembl:ENST00000476873(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005615"(extracellular space)|go:"GO:0006915"(apoptotic process)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0042379"(chemokine receptor binding)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055074"(calcium ion homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071624"(positive regulation of granulocyte chemotaxis)|go:"GO:0090026"(positive regulation of monocyte chemotaxis)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR028493|mint:Q9HCY8|rcsb pdb:2M0R - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZPJCWdA2YqOqXgfSRfDQCoEsyoA9606 rogid:8XSIQKZSb+jAmTmawRUTHjcGwb49606 rigid:C8mTQ5FpkaIXmhKmlb3vl+UFGsI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P13010 uniprotkb:P12956 intact:EBI-357997|uniprotkb:A8K3X5|uniprotkb:Q0Z7V0|uniprotkb:Q53HH7|uniprotkb:Q7M4N0|uniprotkb:Q4VBQ5|uniprotkb:Q9UCQ0|uniprotkb:Q9UCQ1|ensembl:ENSP00000375977|ensembl:ENSP00000375978 intact:EBI-353208|ensembl:ENSP00000352257|ensembl:ENSP00000353192|ensembl:ENSP00000384257|intact:EBI-2843064|uniprotkb:Q6FG89|uniprotkb:Q9UCQ2|uniprotkb:Q9UCQ3|intact:EBI-8456785|intact:MINT-8429298|uniprotkb:B1AHC8 psi-mi:xrcc5_human(display_long)|uniprotkb:XRCC5(gene name)|psi-mi:XRCC5(display_short)|uniprotkb:G22P2(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 80 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p86(gene name synonym)|uniprotkb:86 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Ku86(gene name synonym)|uniprotkb:Ku80(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 85 kDa subunit(gene name synonym)|uniprotkb:Nuclear factor IV(gene name synonym)|uniprotkb:DNA repair protein XRCC5(gene name synonym)|uniprotkb:"X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)"(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 2(gene name synonym) psi-mi:xrcc6_human(display_long)|uniprotkb:XRCC6(gene name)|psi-mi:XRCC6(display_short)|uniprotkb:G22P1(gene name synonym)|uniprotkb:ATP-dependent DNA helicase II 70 kDa subunit(gene name synonym)|uniprotkb:Lupus Ku autoantigen protein p70(gene name synonym)|uniprotkb:70 kDa subunit of Ku antigen(gene name synonym)|uniprotkb:Thyroid-lupus autoantigen(gene name synonym)|uniprotkb:CTC box-binding factor 75 kDa subunit(gene name synonym)|uniprotkb:DNA repair protein XRCC6(gene name synonym)|uniprotkb:X-ray repair complementing defective repair in Chinese hamster cells 6(gene name synonym)|uniprotkb:ATP-dependent DNA helicase 2 subunit 1(gene name synonym)|uniprotkb:5'-deoxyribose-5-phosphate lyase Ku70(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486946|imex:IM-26985-299 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_066964.1|ensembl:ENST00000392132(transcript)|ensembl:ENSG00000079246(gene)|dip:DIP-31379N|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045027"(DNA end binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0070198"(protein localization to chromosome, telomeric region)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0090734"(site of DNA damage)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0032204"(regulation of telomere maintenance)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034462"(small-subunit processome assembly)|go:"GO:0034511"(U3 snoRNA binding)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042493"|ensembl:ENST00000392133(transcript)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008047"(enzyme activator activity)|go:"GO:1904430"(negative regulation of t-circle formation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR002035(von Willebrand factor, type A)|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR014893(Ku, C-terminal)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR024193|interpro:IPR036465|interpro:IPR036494|mint:P13010|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1Q2Z|rcsb pdb:1RW2|rcsb pdb:3RZ9|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZH6|rcsb pdb:6ZHA|rcsb pdb:6ZHE|rcsb pdb:7AXZ|rcsb pdb:7K0Y|rcsb pdb:7K17|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695 go:"GO:0043564"("Ku70:Ku80 complex")|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045621"(positive regulation of lymphocyte differentiation)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0051575"(5'-deoxyribose-5-phosphate lyase activity)|go:"GO:0070419"(nonhomologous end joining complex)|go:"GO:0071475"(cellular hyperosmotic salinity response)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071481"(cellular response to X-ray)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097680"(double-strand break repair via classical nonhomologous end joining)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR005161(Ku70/Ku80, N-terminal alpha/beta)|interpro:IPR006164(DNA helicase, ATP-dependent, Ku type)|interpro:IPR006165(DNA helicase, ATP-dependent, Ku70 subunit)|interpro:IPR016194(Spen Paralogue and Orthologue C-terminal-like)|interpro:IPR027388|interpro:IPR036361|interpro:IPR036465|mint:P12956|rcsb pdb:1JEQ|rcsb pdb:1JEY|rcsb pdb:1JJR|rcsb pdb:3RZX|rcsb pdb:5Y3R|rcsb pdb:6ERF|rcsb pdb:6ERG|rcsb pdb:6ERH|rcsb pdb:6ZHA|interpro:IPR005160(Ku70/Ku80 C-terminal arm)|rcsb pdb:6ZHE|rcsb pdb:7AXZ|interpro:IPR003034(DNA-binding SAP)|rcsb pdb:7K0Y|rcsb pdb:7K1J|rcsb pdb:7K1K|rcsb pdb:7K1N|rcsb pdb:7LSY|rcsb pdb:7LT3|reactome:R-HSA-164843|reactome:R-HSA-1834949|reactome:R-HSA-3270619|reactome:R-HSA-5693571|reactome:R-HSA-6798695|go:"GO:0002218"(activation of innate immune response)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|ensembl:ENSG00000196419(gene)|go:"GO:0005829"(cytosol)|go:"GO:0006266"(DNA ligation)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|ensembl:ENST00000359308(transcript)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|ensembl:ENST00000360079(transcript)|ensembl:ENST00000405878(transcript)|go:"GO:0016020"(membrane)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0016787"(hydrolase activity)|go:"GO:0030332"(cyclin binding)|go:"GO:0000783"(nuclear telomere cap complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042162"(telomeric DNA binding)|refseq:NP_001460.1|refseq:NP_001275906.1|refseq:NP_001275905.1|dip:DIP-24188N - - comment:"author score: 115" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:ZPJCWdA2YqOqXgfSRfDQCoEsyoA9606 rogid:45wj3HmNJ4dfVgw0zc2r3AUZ0Dw9606 rigid:C8mTQ5FpkaIXmhKmlb3vl+UFGsI false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NZC7 uniprotkb:P81605 intact:EBI-4320739|uniprotkb:A8K323|uniprotkb:Q5MYT5|uniprotkb:Q96KM3|uniprotkb:Q96RF2|uniprotkb:Q9BTT8|uniprotkb:Q9NPC9|uniprotkb:Q9NRF4|uniprotkb:Q9NRF5|uniprotkb:Q9NRF6|uniprotkb:Q9NRK1|uniprotkb:Q9NZC5|ensembl:ENSP00000457230 intact:EBI-395625|uniprotkb:P58461|uniprotkb:A5JHP2|uniprotkb:A5JHP3|uniprotkb:Q53YJ2|ensembl:ENSP00000293371 psi-mi:wwox_human(display_long)|uniprotkb:WWOX(gene name)|psi-mi:WWOX(display_short)|uniprotkb:FOR(gene name synonym)|uniprotkb:WOX1(gene name synonym)|uniprotkb:Fragile site FRA16D oxidoreductase(gene name synonym)|uniprotkb:SDR41C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 41C member 1(gene name synonym) psi-mi:dcd_human(display_long)|uniprotkb:AIDD(gene name synonym)|uniprotkb:DSEP(gene name synonym)|uniprotkb:Preproteolysin(gene name synonym)|uniprotkb:DCD(gene name)|psi-mi:DCD(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486931|imex:IM-26985-75 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057457.1|refseq:NP_570607.1|refseq:NP_001278926.1|ensembl:ENST00000566780(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR036020|interpro:IPR036291|interpro:IPR042732|mint:Q9NZC7|rcsb pdb:1WMV|reactome:R-HSA-1251985|reactome:R-HSA-8866904|reactome:R-HSA-8866907|ensembl:ENSG00000186153(gene) refseq:NP_444513.1|refseq:NP_001287783.1|ensembl:ENSG00000161634(gene)|ensembl:ENST00000293371(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008233"(peptidase activity)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR028130|interpro:IPR043557|mint:P81605|rcsb pdb:2KSG|rcsb pdb:2NDK|rcsb pdb:2YMK|rcsb pdb:6SHK|reactome:R-HSA-6803157 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:YMGESSlld4QIPoFrcPX3zhwIy2E9606 rogid:M8PkKVWx98nhtd79ods05mqw8Ls9606 rigid:Gszk7RUWgdOTvbpE6vsIaMqw1EE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NZC7 uniprotkb:P24539 intact:EBI-4320739|uniprotkb:A8K323|uniprotkb:Q5MYT5|uniprotkb:Q96KM3|uniprotkb:Q96RF2|uniprotkb:Q9BTT8|uniprotkb:Q9NPC9|uniprotkb:Q9NRF4|uniprotkb:Q9NRF5|uniprotkb:Q9NRF6|uniprotkb:Q9NRK1|uniprotkb:Q9NZC5|ensembl:ENSP00000457230 intact:EBI-1044810|uniprotkb:Q9BQ68|uniprotkb:Q9BRU8|ensembl:ENSP00000358737 psi-mi:wwox_human(display_long)|uniprotkb:WWOX(gene name)|psi-mi:WWOX(display_short)|uniprotkb:FOR(gene name synonym)|uniprotkb:WOX1(gene name synonym)|uniprotkb:Fragile site FRA16D oxidoreductase(gene name synonym)|uniprotkb:SDR41C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 41C member 1(gene name synonym) psi-mi:at5f1_human(display_long)|uniprotkb:ATP5PB(gene name)|psi-mi:ATP5PB(display_short)|uniprotkb:ATP synthase peripheral stalk-membrane subunit b(gene name synonym)|uniprotkb:"ATP synthase proton-transporting mitochondrial F(0) complex subunit B1"(gene name synonym)|uniprotkb:ATP synthase subunit b(gene name synonym)|uniprotkb:ATP5F1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486931|imex:IM-26985-75 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057457.1|refseq:NP_570607.1|refseq:NP_001278926.1|ensembl:ENST00000566780(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR036020|interpro:IPR036291|interpro:IPR042732|mint:Q9NZC7|rcsb pdb:1WMV|reactome:R-HSA-1251985|reactome:R-HSA-8866904|reactome:R-HSA-8866907|ensembl:ENSG00000186153(gene) refseq:NP_001679.2|ensembl:ENSG00000116459(gene)|ensembl:ENST00000369722(transcript)|go:"GO:0000276"("mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)")|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005753"(mitochondrial proton-transporting ATP synthase complex)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0015078"(proton transmembrane transporter activity)|go:"GO:0015986"(ATP synthesis coupled proton transport)|go:"GO:0016020"(membrane)|go:"GO:0021762"(substantia nigra development)|interpro:IPR008688(ATPase, F0 complex, subunit B, mitochondrial)|interpro:IPR013837(ATPase, F0 complex subunit B, mitochondrial, metazoa)|mint:P24539|reactome:R-HSA-163210|reactome:R-HSA-8949613|go:"GO:0042776"(mitochondrial ATP synthesis coupled proton transport) - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:YMGESSlld4QIPoFrcPX3zhwIy2E9606 rogid:n1HuorsLzONcID7ccOL9qEsODLE9606 rigid:Gszk7RUWgdOTvbpE6vsIaMqw1EE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9NZC7 uniprotkb:P0CG04 intact:EBI-4320739|uniprotkb:A8K323|uniprotkb:Q5MYT5|uniprotkb:Q96KM3|uniprotkb:Q96RF2|uniprotkb:Q9BTT8|uniprotkb:Q9NPC9|uniprotkb:Q9NRF4|uniprotkb:Q9NRF5|uniprotkb:Q9NRF6|uniprotkb:Q9NRK1|uniprotkb:Q9NZC5|ensembl:ENSP00000457230 intact:EBI-1221063|uniprotkb:P80423|uniprotkb:A0M8Q4|uniprotkb:P01842|uniprotkb:A0A075B6K8 psi-mi:wwox_human(display_long)|uniprotkb:WWOX(gene name)|psi-mi:WWOX(display_short)|uniprotkb:FOR(gene name synonym)|uniprotkb:WOX1(gene name synonym)|uniprotkb:Fragile site FRA16D oxidoreductase(gene name synonym)|uniprotkb:SDR41C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 41C member 1(gene name synonym) psi-mi:iglc1_human(display_long)|uniprotkb:IGLC1(gene name)|psi-mi:IGLC1(display_short)|uniprotkb:Ig lambda chain C region MGC(gene name synonym)|uniprotkb:Ig lambda-1 chain C region(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486931|imex:IM-26985-75 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_057457.1|refseq:NP_570607.1|refseq:NP_001278926.1|ensembl:ENST00000566780(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR036020|interpro:IPR036291|interpro:IPR042732|mint:Q9NZC7|rcsb pdb:1WMV|reactome:R-HSA-1251985|reactome:R-HSA-8866904|reactome:R-HSA-8866907|ensembl:ENSG00000186153(gene) interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|mint:P0CG04|interpro:IPR036179|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0034987"(immunoglobulin receptor binding)|go:"GO:0042571"(immunoglobulin complex, circulating)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|rcsb pdb:1ZVO|rcsb pdb:2FB4|rcsb pdb:2IG2|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|go:"GO:0045087"(innate immune response)|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664422|reactome:R-HSA-977606|reactome:R-HSA-983695|reactome:R-HSA-9664323 - - comment:"author score: 45" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:YMGESSlld4QIPoFrcPX3zhwIy2E9606 rogid:OOdxBXPI2Jzf9HxurFZjk3/L1DM9606 rigid:Gszk7RUWgdOTvbpE6vsIaMqw1EE false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P2S5 uniprotkb:Q96QA5 intact:EBI-1054904|uniprotkb:Q5T0D6|uniprotkb:Q9BUH7|uniprotkb:Q9NTK7|uniprotkb:Q9NX56|ensembl:ENSP00000270708 intact:EBI-11320924|uniprotkb:Q86VE7|uniprotkb:Q8N1M6|uniprotkb:Q32MC5|ensembl:ENSP00000301659|ensembl:ENSP00000490739 psi-mi:wrp73_human(display_long)|uniprotkb:WRAP73(gene name)|psi-mi:WRAP73(display_short)|uniprotkb:WDR8(gene name synonym)|uniprotkb:WD repeat-containing protein 8(gene name synonym)|uniprotkb:WD repeat-containing protein antisense to TP73 gene(gene name synonym) psi-mi:gsdma_human(display_long)|uniprotkb:GSDMA(gene name)|psi-mi:GSDMA(display_short)|uniprotkb:GSDM(gene name synonym)|uniprotkb:GSDM1(gene name synonym)|uniprotkb:Gasdermin-1(gene name synonym)|uniprotkb:FKSG9(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486895|imex:IM-26985-377 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060288.3|ensembl:ENSG00000116213(gene)|ensembl:ENST00000270708(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0030030"(cell projection organization)|go:"GO:0036064"(ciliary basal body)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1902440"(protein localization to mitotic spindle pole body)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|go:"GO:1990811"(MWP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|mint:Q9P2S5 refseq:NP_835465.2|refseq:XP_006721895.1|ensembl:ENSG00000167914(gene)|ensembl:ENST00000301659(transcript)|ensembl:ENST00000635792(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070269"(pyroptosis)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|interpro:IPR007677(DFNA5 protein)|interpro:IPR040460|interpro:IPR041263|mint:Q96QA5 - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:H5LC0HbUA2MqmXzFg7y256KDg2U9606 rogid:D48ojc01zrvJ4qw6PMxC9Sp8HMY9606 rigid:0EnwiDKN4ihl3b+5sO1NM0f5zZs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P2S5 uniprotkb:P07910 intact:EBI-1054904|uniprotkb:Q5T0D6|uniprotkb:Q9BUH7|uniprotkb:Q9NTK7|uniprotkb:Q9NX56|ensembl:ENSP00000270708 intact:EBI-357966|uniprotkb:P22628|uniprotkb:Q53EX2|uniprotkb:Q59FD3|uniprotkb:Q5FWE8|uniprotkb:Q86SF8|uniprotkb:Q86U45|uniprotkb:Q96HK7|uniprotkb:Q96HM4|uniprotkb:Q96IY5|uniprotkb:Q9BTS3|uniprotkb:D3DS19|uniprotkb:D3DS22|intact:EBI-28976506|ensembl:ENSP00000404848|ensembl:ENSP00000451291|ensembl:ENSP00000452276 psi-mi:wrp73_human(display_long)|uniprotkb:WRAP73(gene name)|psi-mi:WRAP73(display_short)|uniprotkb:WDR8(gene name synonym)|uniprotkb:WD repeat-containing protein 8(gene name synonym)|uniprotkb:WD repeat-containing protein antisense to TP73 gene(gene name synonym) psi-mi:hnrpc_human(display_long)|uniprotkb:HNRNPC(gene name)|psi-mi:HNRNPC(display_short)|uniprotkb:HNRPC(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486895|imex:IM-26985-377 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060288.3|ensembl:ENSG00000116213(gene)|ensembl:ENST00000270708(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0030030"(cell projection organization)|go:"GO:0036064"(ciliary basal body)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1902440"(protein localization to mitotic spindle pole body)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|go:"GO:1990811"(MWP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|mint:Q9P2S5 refseq:NP_001070910.1|refseq:NP_001070911.1|refseq:NP_004491.2|refseq:NP_112604.2|ensembl:ENSP00000404848|ensembl:ENST00000430246|ensembl:ENSP00000442816|ensembl:ENST00000553300|ensembl:ENSP00000450544|ensembl:ENSP00000451291|ensembl:ENST00000554969|ensembl:ENSP00000452276|ensembl:ENSP00000450725|ensembl:ENST00000555883|ensembl:ENSP00000450629|ensembl:ENST00000556628|ensembl:ENSP00000451652|ensembl:ENST00000556897|ensembl:ENSP00000451176|refseq:XP_011535010.1|refseq:XP_011535011.1|refseq:XP_011535012.1|refseq:XP_011535013.1|refseq:XP_011535014.1|refseq:XP_016876741.1|refseq:XP_016876742.1|dip:DIP-29854N|refseq:XP_006720188.1|ensembl:ENSG00000092199(gene)|ensembl:ENST00000420743(transcript)|ensembl:ENST00000554455(transcript)|ensembl:ENST00000557201(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005697"(telomerase holoenzyme complex)|go:"GO:0005829"(cytosol)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008380"(RNA splicing)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043044"|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070935"(3'-UTR-mediated mRNA stabilization)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1990247"(N6-methyladenosine-containing RNA binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR017347(Heterogeneous nuclear ribonucleoprotein C, Raly)|interpro:IPR035979|mint:P07910|rcsb pdb:1TXP|rcsb pdb:1WF2|rcsb pdb:2MXY|rcsb pdb:2MZ1|rcsb pdb:3LN4|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9013418|reactome:R-HSA-9013422 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:H5LC0HbUA2MqmXzFg7y256KDg2U9606 rogid:Fj5tiH0wrNUjTnsURIg8dB8laMg9606 rigid:0EnwiDKN4ihl3b+5sO1NM0f5zZs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P2S5 uniprotkb:Q15517 intact:EBI-1054904|uniprotkb:Q5T0D6|uniprotkb:Q9BUH7|uniprotkb:Q9NTK7|uniprotkb:Q9NX56|ensembl:ENSP00000270708 intact:EBI-953708|ensembl:ENSP00000259726|ensembl:ENSP00000388386|ensembl:ENSP00000392863|ensembl:ENSP00000399604|uniprotkb:Q9NRH4|uniprotkb:Q9NRH5|uniprotkb:Q9NRH6|uniprotkb:Q9NRH7|uniprotkb:Q9NRH8|uniprotkb:Q9UBH8|uniprotkb:Q9UIN6|uniprotkb:Q9UIN7|uniprotkb:Q9UIN8|uniprotkb:Q9UIN9|uniprotkb:Q9UIP0|uniprotkb:O43509|uniprotkb:Q5SQ85|uniprotkb:Q5STD2|uniprotkb:Q7LA70|uniprotkb:Q7LA71|uniprotkb:Q86Z04|uniprotkb:Q8IZU4|uniprotkb:Q8IZU5|uniprotkb:Q8IZU6|uniprotkb:Q8N5P3|uniprotkb:Q95IF9|uniprotkb:Q9NP52|uniprotkb:Q9NPE0|uniprotkb:Q9NPG5|uniprotkb:B0S7V2|uniprotkb:B0UYZ7 psi-mi:wrp73_human(display_long)|uniprotkb:WRAP73(gene name)|psi-mi:WRAP73(display_short)|uniprotkb:WDR8(gene name synonym)|uniprotkb:WD repeat-containing protein 8(gene name synonym)|uniprotkb:WD repeat-containing protein antisense to TP73 gene(gene name synonym) psi-mi:cdsn_human(display_long)|uniprotkb:CDSN(gene name)|psi-mi:CDSN(display_short)|uniprotkb:S protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486895|imex:IM-26985-377 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060288.3|ensembl:ENSG00000116213(gene)|ensembl:ENST00000270708(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0030030"(cell projection organization)|go:"GO:0036064"(ciliary basal body)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1902440"(protein localization to mitotic spindle pole body)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|go:"GO:1990811"(MWP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|mint:Q9P2S5 ensembl:ENSG00000137197(gene)|ensembl:ENSG00000237114(gene)|ensembl:ENSG00000237123(gene)|ensembl:ENSG00000237165(gene)|ensembl:ENST00000259726(transcript)|ensembl:ENST00000418599(transcript)|ensembl:ENST00000445893(transcript)|ensembl:ENST00000457875(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0003336"(corneocyte desquamation)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0008544"(epidermis development)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1905716"(negative regulation of cornification)|interpro:IPR026087|mint:Q15517|reactome:R-HSA-6809371|refseq:NP_001255.3 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:H5LC0HbUA2MqmXzFg7y256KDg2U9606 rogid:2SaKSq9Py2cPLlytyEiH8znQcd49606 rigid:0EnwiDKN4ihl3b+5sO1NM0f5zZs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P2S5 uniprotkb:P07355 intact:EBI-1054904|uniprotkb:Q5T0D6|uniprotkb:Q9BUH7|uniprotkb:Q9NTK7|uniprotkb:Q9NX56|ensembl:ENSP00000270708 intact:EBI-352622|uniprotkb:Q567R4|uniprotkb:Q96DD5|intact:EBI-2211824|uniprotkb:Q6N0B3|uniprotkb:Q8TBV2|uniprotkb:Q9UDH8|ensembl:ENSP00000379342|ensembl:ENSP00000387545|ensembl:ENSP00000411352|ensembl:ENSP00000452858|ensembl:ENSP00000452895|ensembl:ENSP00000452981|ensembl:ENSP00000453694|ensembl:ENSP00000453859|ensembl:ENSP00000503447|ensembl:ENSP00000503757|ensembl:ENSP00000503855|ensembl:ENSP00000504035|ensembl:ENSP00000504164 psi-mi:wrp73_human(display_long)|uniprotkb:WRAP73(gene name)|psi-mi:WRAP73(display_short)|uniprotkb:WDR8(gene name synonym)|uniprotkb:WD repeat-containing protein 8(gene name synonym)|uniprotkb:WD repeat-containing protein antisense to TP73 gene(gene name synonym) psi-mi:anxa2_human(display_long)|uniprotkb:ANXA2(gene name)|psi-mi:ANXA2(display_short)|uniprotkb:ANX2(gene name synonym)|uniprotkb:ANX2L4(gene name synonym)|uniprotkb:CAL1H(gene name synonym)|uniprotkb:LPC2D(gene name synonym)|uniprotkb:Annexin-2(gene name synonym)|uniprotkb:Annexin II(gene name synonym)|uniprotkb:Lipocortin II(gene name synonym)|uniprotkb:Calpactin I heavy chain(gene name synonym)|uniprotkb:Chromobindin-8(gene name synonym)|uniprotkb:p36(gene name synonym)|uniprotkb:Protein I(gene name synonym)|uniprotkb:Placental anticoagulant protein IV(gene name synonym)|uniprotkb:Calpactin-1 heavy chain(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486895|imex:IM-26985-377 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060288.3|ensembl:ENSG00000116213(gene)|ensembl:ENST00000270708(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0030030"(cell projection organization)|go:"GO:0036064"(ciliary basal body)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1902440"(protein localization to mitotic spindle pole body)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|go:"GO:1990811"(MWP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|mint:Q9P2S5 refseq:NP_001002857.1|refseq:NP_001002858.1|refseq:NP_001129487.1|refseq:NP_004030.1|refseq:XP_016877579.1|refseq:XP_016877580.1|ensembl:ENSG00000182718(gene)|ensembl:ENST00000396024(transcript)|ensembl:ENST00000421017(transcript)|ensembl:ENST00000451270(transcript)|ensembl:ENST00000557906(transcript)|ensembl:ENST00000558558(transcript)|ensembl:ENST00000559818(transcript)|ensembl:ENST00000559956(transcript)|ensembl:ENST00000560468(transcript)|ensembl:ENST00000677968(transcript)|ensembl:ENST00000678061(transcript)|ensembl:ENST00000678450(transcript)|ensembl:ENST00000678870(transcript)|ensembl:ENST00000679109(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001726"(ruffle)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005262"(calcium channel activity)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007589"(body fluid secretion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0009986"(cell surface)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030199"(collagen fibril organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032804"(negative regulation of low-density lipoprotein particle receptor catabolic process)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0036035"(osteoclast development)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042730"(fibrinolysis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0044090"(positive regulation of vacuole organization)|go:"GO:0044354"(macropinosome)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044730"(bone sialoprotein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0046790"(virion binding)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0005509"(calcium ion binding)|rcsb pdb:2HYU|rcsb pdb:2HYV|rcsb pdb:2HYW|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRH|rcsb pdb:5LPU|rcsb pdb:5LPX|rcsb pdb:5LQ0|rcsb pdb:5LQ2|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWQ|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY|reactome:R-HSA-445355|reactome:R-HSA-6798695|reactome:R-HSA-75205|reactome:R-HSA-8950505|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1905581"(positive regulation of low-density lipoprotein particle clearance)|go:"GO:1905597"(positive regulation of low-density lipoprotein particle receptor binding)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|go:"GO:1905602"(positive regulation of receptor-mediated endocytosis involved in cholesterol transport)|go:"GO:1990665"(AnxA2-p11 complex)|go:"GO:1990667"(PCSK9-AnxA2 complex)|interpro:IPR001464(Annexin)|interpro:IPR002389(Annexin, type II)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P07355|rcsb pdb:1W7B|rcsb pdb:1XJL|go:"GO:0097066"(response to thyroid hormone) - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:H5LC0HbUA2MqmXzFg7y256KDg2U9606 rogid:jcB4Dt0LFv8YaBUnC2BSTCshveg9606 rigid:0EnwiDKN4ihl3b+5sO1NM0f5zZs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P2S5 uniprotkb:P81605 intact:EBI-1054904|uniprotkb:Q5T0D6|uniprotkb:Q9BUH7|uniprotkb:Q9NTK7|uniprotkb:Q9NX56|ensembl:ENSP00000270708 intact:EBI-395625|uniprotkb:P58461|uniprotkb:A5JHP2|uniprotkb:A5JHP3|uniprotkb:Q53YJ2|ensembl:ENSP00000293371 psi-mi:wrp73_human(display_long)|uniprotkb:WRAP73(gene name)|psi-mi:WRAP73(display_short)|uniprotkb:WDR8(gene name synonym)|uniprotkb:WD repeat-containing protein 8(gene name synonym)|uniprotkb:WD repeat-containing protein antisense to TP73 gene(gene name synonym) psi-mi:dcd_human(display_long)|uniprotkb:AIDD(gene name synonym)|uniprotkb:DSEP(gene name synonym)|uniprotkb:Preproteolysin(gene name synonym)|uniprotkb:DCD(gene name)|psi-mi:DCD(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486895|imex:IM-26985-377 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060288.3|ensembl:ENSG00000116213(gene)|ensembl:ENST00000270708(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0030030"(cell projection organization)|go:"GO:0036064"(ciliary basal body)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1902440"(protein localization to mitotic spindle pole body)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|go:"GO:1990811"(MWP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|mint:Q9P2S5 refseq:NP_444513.1|refseq:NP_001287783.1|ensembl:ENSG00000161634(gene)|ensembl:ENST00000293371(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0008233"(peptidase activity)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051873"(killing by host of symbiont cells)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0070062"(extracellular exosome)|interpro:IPR028130|interpro:IPR043557|mint:P81605|rcsb pdb:2KSG|rcsb pdb:2NDK|rcsb pdb:2YMK|rcsb pdb:6SHK|reactome:R-HSA-6803157 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:H5LC0HbUA2MqmXzFg7y256KDg2U9606 rogid:M8PkKVWx98nhtd79ods05mqw8Ls9606 rigid:0EnwiDKN4ihl3b+5sO1NM0f5zZs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P2S5 uniprotkb:P16403 intact:EBI-1054904|uniprotkb:Q5T0D6|uniprotkb:Q9BUH7|uniprotkb:Q9NTK7|uniprotkb:Q9NX56|ensembl:ENSP00000270708 intact:EBI-358372|ensembl:ENSP00000339566|uniprotkb:A8K4I2 psi-mi:wrp73_human(display_long)|uniprotkb:WRAP73(gene name)|psi-mi:WRAP73(display_short)|uniprotkb:WDR8(gene name synonym)|uniprotkb:WD repeat-containing protein 8(gene name synonym)|uniprotkb:WD repeat-containing protein antisense to TP73 gene(gene name synonym) psi-mi:h12_human(display_long)|uniprotkb:H1-2(gene name)|psi-mi:H1-2(display_short)|uniprotkb:H1F2(gene name synonym)|uniprotkb:HIST1H1C(gene name synonym)|uniprotkb:Histone H1c(gene name synonym)|uniprotkb:Histone H1d(gene name synonym)|uniprotkb:Histone H1s-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486895|imex:IM-26985-377 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060288.3|ensembl:ENSG00000116213(gene)|ensembl:ENST00000270708(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0030030"(cell projection organization)|go:"GO:0036064"(ciliary basal body)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1902440"(protein localization to mitotic spindle pole body)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|go:"GO:1990811"(MWP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|mint:Q9P2S5 refseq:NP_005310.1|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0098532"(histone H3-K27 trimethylation)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:P16403|reactome:R-HSA-140342|reactome:R-HSA-2559584|ensembl:ENSG00000187837(gene)|ensembl:ENST00000343677(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000786"(nucleosome)|go:"GO:0000791"(euchromatin)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0035327"|go:"GO:0045910"(negative regulation of DNA recombination)|dip:DIP-36359N - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:H5LC0HbUA2MqmXzFg7y256KDg2U9606 rogid:eRT5bTyBJUg6nRANMRYZekT4N+g9606 rigid:0EnwiDKN4ihl3b+5sO1NM0f5zZs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P2S5 uniprotkb:O75223 intact:EBI-1054904|uniprotkb:Q5T0D6|uniprotkb:Q9BUH7|uniprotkb:Q9NTK7|uniprotkb:Q9NX56|ensembl:ENSP00000270708 intact:EBI-6912130|ensembl:ENSP00000275428|uniprotkb:B8ZZR8|uniprotkb:Q9BS37|uniprotkb:B8ZZN4|uniprotkb:B2RDN0 psi-mi:wrp73_human(display_long)|uniprotkb:WRAP73(gene name)|psi-mi:WRAP73(display_short)|uniprotkb:WDR8(gene name synonym)|uniprotkb:WD repeat-containing protein 8(gene name synonym)|uniprotkb:WD repeat-containing protein antisense to TP73 gene(gene name synonym) psi-mi:ggct_human(display_long)|uniprotkb:C7orf24(gene name synonym)|uniprotkb:CRF21(gene name synonym)|uniprotkb:Cytochrome c-releasing factor 21(gene name synonym)|uniprotkb:GGCT(gene name)|psi-mi:GGCT(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486895|imex:IM-26985-377 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060288.3|ensembl:ENSG00000116213(gene)|ensembl:ENST00000270708(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0030030"(cell projection organization)|go:"GO:0036064"(ciliary basal body)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1902440"(protein localization to mitotic spindle pole body)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|go:"GO:1990811"(MWP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|mint:Q9P2S5 ensembl:ENSG00000006625(gene)|ensembl:ENST00000275428(transcript)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0003839"(gamma-glutamylcyclotransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013024(Butirosin biosynthesis, BtrG-like)|interpro:IPR017939|interpro:IPR036568|mint:O75223|rcsb pdb:2I5T|rcsb pdb:2PN7|rcsb pdb:2Q53|rcsb pdb:2RBH|rcsb pdb:3CRY|reactome:R-HSA-174403|refseq:NP_001186744.1|refseq:NP_001186745.1|refseq:NP_001186746.1|refseq:NP_076956.1 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:H5LC0HbUA2MqmXzFg7y256KDg2U9606 rogid:OPoR51zHOj/GAUlzTuVvYmxaaxk9606 rigid:0EnwiDKN4ihl3b+5sO1NM0f5zZs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P2S5 uniprotkb:P05089 intact:EBI-1054904|uniprotkb:Q5T0D6|uniprotkb:Q9BUH7|uniprotkb:Q9NTK7|uniprotkb:Q9NX56|ensembl:ENSP00000270708 intact:EBI-2513844|uniprotkb:Q5JWT6|uniprotkb:Q5JWT5|uniprotkb:Q9BS50|uniprotkb:Q8TE72|uniprotkb:A6NEA0|ensembl:ENSP00000357066 psi-mi:wrp73_human(display_long)|uniprotkb:WRAP73(gene name)|psi-mi:WRAP73(display_short)|uniprotkb:WDR8(gene name synonym)|uniprotkb:WD repeat-containing protein 8(gene name synonym)|uniprotkb:WD repeat-containing protein antisense to TP73 gene(gene name synonym) psi-mi:argi1_human(display_long)|uniprotkb:ARG1(gene name)|psi-mi:ARG1(display_short)|uniprotkb:Type I arginase(gene name synonym)|uniprotkb:Liver-type arginase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486895|imex:IM-26985-377 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060288.3|ensembl:ENSG00000116213(gene)|ensembl:ENST00000270708(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0030030"(cell projection organization)|go:"GO:0036064"(ciliary basal body)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1902440"(protein localization to mitotic spindle pole body)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|go:"GO:1990811"(MWP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|mint:Q9P2S5 refseq:NP_000036.2|refseq:NP_001231367.1|ensembl:ENSG00000118520(gene)|ensembl:ENST00000368087(transcript)|go:"GO:0000050"(urea cycle)|go:"GO:0001889"(liver development)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0002250"(adaptive immune response)|go:"GO:0004053"(arginase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006527"(arginine catabolic process)|go:"GO:0007568"(aging)|go:"GO:0009635"(response to herbicide)|go:"GO:0010042"(response to manganese ion)|go:"GO:0010043"(response to zinc ion)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010963"|go:"GO:0014075"(response to amine)|go:"GO:0019547"(arginine catabolic process to ornithine)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030324"(lung development)|go:"GO:0032964"(collagen biosynthetic process)|go:"GO:0033189"(response to vitamin A)|go:"GO:0033197"(response to vitamin E)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0042832"(defense response to protozoan)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043200"(response to amino acid)|go:"GO:0045087"(innate immune response)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0046686"(response to cadmium ion)|go:"GO:0048678"(response to axon injury)|go:"GO:0051597"(response to methylmercury)|go:"GO:0060135"(maternal process involved in female pregnancy)|go:"GO:0060336"(negative regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070965"(positive regulation of neutrophil mediated killing of fungus)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071377"(cellular response to glucagon stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:2000552"(negative regulation of T-helper 2 cell cytokine production)|interpro:IPR006035(Ureohydrolase)|interpro:IPR014033(Arginase, subgroup)|go:"GO:0060056"(mammary gland involution)|interpro:IPR020855|interpro:IPR023696|mint:P05089|rcsb pdb:1WVA|rcsb pdb:1WVB|rcsb pdb:2AEB|rcsb pdb:2PHA|rcsb pdb:2PHO|rcsb pdb:2PLL|rcsb pdb:2ZAV|rcsb pdb:3DJ8|rcsb pdb:3E6K|rcsb pdb:3E6V|rcsb pdb:3F80|rcsb pdb:3GMZ|rcsb pdb:3GN0|rcsb pdb:3KV2|rcsb pdb:3LP4|rcsb pdb:3LP7|rcsb pdb:3MFV|rcsb pdb:3MFW|rcsb pdb:3MJL|rcsb pdb:3SJT|rcsb pdb:3SKK|rcsb pdb:3TF3|rcsb pdb:3TH7|rcsb pdb:3THE|rcsb pdb:3THH|rcsb pdb:3THJ|rcsb pdb:4FCI|rcsb pdb:4FCK|rcsb pdb:4GSM|rcsb pdb:4GSV|rcsb pdb:4GSZ|rcsb pdb:4GWC|rcsb pdb:4GWD|rcsb pdb:4HWW|rcsb pdb:4HXQ|rcsb pdb:4IE1|rcsb pdb:6Q92|rcsb pdb:6Q9P|rcsb pdb:6QAF|rcsb pdb:6V7C|rcsb pdb:6V7D|rcsb pdb:6V7E|rcsb pdb:6V7F|reactome:R-HSA-6798695|reactome:R-HSA-70635 - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:H5LC0HbUA2MqmXzFg7y256KDg2U9606 rogid:b8HHscDekWZdN1S4OxFTA6rjvn89606 rigid:0EnwiDKN4ihl3b+5sO1NM0f5zZs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P2S5 uniprotkb:P05109 intact:EBI-1054904|uniprotkb:Q5T0D6|uniprotkb:Q9BUH7|uniprotkb:Q9NTK7|uniprotkb:Q9NX56|ensembl:ENSP00000270708 intact:EBI-355281|uniprotkb:Q5SY70|uniprotkb:Q9UC92|uniprotkb:Q9UCJ0|uniprotkb:A8K5L3|uniprotkb:Q9UC84|uniprotkb:Q9UCM6|uniprotkb:D3DV37|ensembl:ENSP00000357721|ensembl:ENSP00000357722 psi-mi:wrp73_human(display_long)|uniprotkb:WRAP73(gene name)|psi-mi:WRAP73(display_short)|uniprotkb:WDR8(gene name synonym)|uniprotkb:WD repeat-containing protein 8(gene name synonym)|uniprotkb:WD repeat-containing protein antisense to TP73 gene(gene name synonym) psi-mi:s10a8_human(display_long)|uniprotkb:S100A8(gene name)|psi-mi:S100A8(display_short)|uniprotkb:CAGA(gene name synonym)|uniprotkb:MRP8(gene name synonym)|uniprotkb:CFAG(gene name synonym)|uniprotkb:S100 calcium-binding protein A8(gene name synonym)|uniprotkb:Calgranulin-A(gene name synonym)|uniprotkb:Migration inhibitory factor-related protein 8(gene name synonym)|uniprotkb:Cystic fibrosis antigen(gene name synonym)|uniprotkb:Leukocyte L1 complex light chain(gene name synonym)|uniprotkb:Calprotectin L1L subunit(gene name synonym)|uniprotkb:Urinary stone protein band A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486895|imex:IM-26985-377 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060288.3|ensembl:ENSG00000116213(gene)|ensembl:ENST00000270708(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0030030"(cell projection organization)|go:"GO:0036064"(ciliary basal body)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1902440"(protein localization to mitotic spindle pole body)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|go:"GO:1990811"(MWP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|mint:Q9P2S5 refseq:NP_001306126.1|refseq:NP_001306127.1|refseq:NP_001306130.1|refseq:NP_002955.2|go:"GO:0042060"(wound healing)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045471"(response to ethanol)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070488"(neutrophil aggregation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028474|go:"GO:0035662"(Toll-like receptor 4 binding)|mint:P05109|rcsb pdb:1MR8|rcsb pdb:1XK4|rcsb pdb:4GGF|rcsb pdb:4XJK|rcsb pdb:5HLO|rcsb pdb:5HLV|rcsb pdb:5W1F|rcsb pdb:6DS2|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5668599|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-6799990|ensembl:ENST00000368732(transcript)|ensembl:ENST00000368733(transcript)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002526"(acute inflammatory response)|ensembl:ENSG00000143546(gene)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0002793"(positive regulation of peptide secretion)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010043"(response to zinc ion)|go:"GO:0014002"(astrocyte development)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032119"(sequestering of zinc ion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035425"(autocrine signaling)|dip:DIP-1165N - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:H5LC0HbUA2MqmXzFg7y256KDg2U9606 rogid:3Okfhj8fxclZ0Uo/Fa1Z89qC8Ec9606 rigid:0EnwiDKN4ihl3b+5sO1NM0f5zZs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9P2S5 uniprotkb:P22531 intact:EBI-1054904|uniprotkb:Q5T0D6|uniprotkb:Q9BUH7|uniprotkb:Q9NTK7|uniprotkb:Q9NX56|ensembl:ENSP00000270708 intact:EBI-2556846|uniprotkb:Q5T9T4|uniprotkb:Q96RM2|ensembl:ENSP00000357739|ensembl:ENSP00000357740 psi-mi:wrp73_human(display_long)|uniprotkb:WRAP73(gene name)|psi-mi:WRAP73(display_short)|uniprotkb:WDR8(gene name synonym)|uniprotkb:WD repeat-containing protein 8(gene name synonym)|uniprotkb:WD repeat-containing protein antisense to TP73 gene(gene name synonym) psi-mi:spr2e_human(display_long)|uniprotkb:Small proline-rich protein II(gene name synonym)|uniprotkb:SPRR2E(gene name)|psi-mi:SPRR2E(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486895|imex:IM-26985-377 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060288.3|ensembl:ENSG00000116213(gene)|ensembl:ENST00000270708(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0030030"(cell projection organization)|go:"GO:0036064"(ciliary basal body)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:1902440"(protein localization to mitotic spindle pole body)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|go:"GO:1990811"(MWP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|mint:Q9P2S5 refseq:NP_001019380.2|ensembl:ENSG00000203785(gene)|ensembl:ENST00000368750(transcript)|ensembl:ENST00000368751(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030280"(structural constituent of skin epidermis)|go:"GO:0031424"(keratinization)|interpro:IPR029142|mint:P22531|reactome:R-HSA-6809371 - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:H5LC0HbUA2MqmXzFg7y256KDg2U9606 rogid:Pwemojva9RHkLb7mVmctpxenpf49606 rigid:0EnwiDKN4ihl3b+5sO1NM0f5zZs false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-25401924 uniprotkb:Q9BZ95 - intact:EBI-3390132|intact:EBI-10986793|intact:EBI-28977318|uniprotkb:Q9H2M8|uniprotkb:Q3B796|uniprotkb:Q6ZSA5|uniprotkb:Q9H9W9|uniprotkb:Q9NXA6|uniprotkb:Q9BYU8|uniprotkb:Q1RMD3|uniprotkb:Q9BYU9|uniprotkb:D3DSX1|uniprotkb:B7ZL11|ensembl:ENSP00000313983 psi-mi:rs4x_rs4y1_rs4y2_human(display_short)|psi-mi:EBI-25401924(display_long) psi-mi:nsd3_human(display_long)|uniprotkb:NSD3(gene name)|psi-mi:NSD3(display_short)|uniprotkb:Nuclear SET domain-containing protein 3(gene name synonym)|uniprotkb:Protein whistle(gene name synonym)|uniprotkb:WHSC1-like 1 isoform 9 with methyltransferase activity to lysine(gene name synonym)|uniprotkb:WHSC1L1(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1-like protein 1(gene name synonym)|uniprotkb:DC28(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-25486886|imex:IM-26985-519 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:1304"(molecule set) psi-mi:"MI:0326"(protein) - ensembl:ENST00000316985|ensembl:ENSP00000313410|ensembl:ENSP00000313983|ensembl:ENST00000433384|ensembl:ENSP00000393284|ensembl:ENST00000527502|ensembl:ENSP00000434730|refseq:NP_060248.2|refseq:NP_075447.1|dip:DIP-62074N|ensembl:ENSG00000147548(gene)|ensembl:ENST00000317025(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0016571"(histone methylation)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0140537"(transcription regulator activator activity)|go:"GO:2001255"(positive regulation of histone H3-K36 trimethylation)|interpro:IPR000313(PWWP)|interpro:IPR001214(SET)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR006560(AWS)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR041306|mint:Q9BZ95|rcsb pdb:2DAQ|rcsb pdb:2NCZ|rcsb pdb:2ND1|rcsb pdb:4GND|rcsb pdb:4GNE|rcsb pdb:4GNF|rcsb pdb:4GNG|rcsb pdb:4RXJ|rcsb pdb:5UPD|rcsb pdb:6CEN|rcsb pdb:6G24|rcsb pdb:6G25|rcsb pdb:6G27|rcsb pdb:6G29|rcsb pdb:6G2B|rcsb pdb:6G2C|rcsb pdb:6G2E|rcsb pdb:6G2F|rcsb pdb:6G2O|rcsb pdb:6G3P|rcsb pdb:6G3T|rcsb pdb:7CRP|rcsb pdb:7CRQ|rcsb pdb:7CRR|rcsb pdb:7JYN|reactome:R-HSA-3214841 - comment:P22090,P62701,Q8TD47|comment:"author score: 14" - figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2021/09/28 - rogid:3REraEl+Y81ooPedBVSqLngvlGU9606 - false - tandem tag:n-n - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O96028 uniprotkb:P06702 intact:EBI-2693298|uniprotkb:A2A2T3|uniprotkb:A2A2T4|uniprotkb:A7MCZ1|uniprotkb:O96031|uniprotkb:Q4VBY8|uniprotkb:Q672J1|uniprotkb:Q6IS00|uniprotkb:Q86V01|uniprotkb:Q9BZB4|uniprotkb:Q9UI92|uniprotkb:Q9UPR2|intact:EBI-3438110|uniprotkb:D3DVQ2|uniprotkb:A2A2T2|intact:EBI-28971215|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENSP00000423972 intact:EBI-1055001|uniprotkb:Q6FGA1|uniprotkb:Q9NYM0|uniprotkb:Q9UCJ1|uniprotkb:D3DV36|ensembl:ENSP00000357727 psi-mi:nsd2_human(display_long)|uniprotkb:NSD2(gene name)|psi-mi:NSD2(display_short)|uniprotkb:KIAA1090(gene name synonym)|uniprotkb:MMSET(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Protein trithorax-5(gene name synonym)|uniprotkb:TRX5(gene name synonym)|uniprotkb:WHSC1(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein(gene name synonym) psi-mi:s10a9_human(display_long)|uniprotkb:S100 calcium-binding protein A9(gene name synonym)|uniprotkb:Calgranulin-B(gene name synonym)|uniprotkb:Migration inhibitory factor-related protein 14(gene name synonym)|uniprotkb:Leukocyte L1 complex heavy chain(gene name synonym)|uniprotkb:Calprotectin L1H subunit(gene name synonym)|uniprotkb:S100A9(gene name)|psi-mi:S100A9(display_short)|uniprotkb:CAGB(gene name synonym)|uniprotkb:CFAG(gene name synonym)|uniprotkb:MRP14(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486814|imex:IM-26985-159 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000329167|ensembl:ENST00000382888|ensembl:ENSP00000372344|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENST00000398261|ensembl:ENSP00000381311|ensembl:ENST00000420906|ensembl:ENSP00000399251|ensembl:ENST00000503128|ensembl:ENSP00000425761|ensembl:ENSP00000423972|ensembl:ENST00000514045|ensembl:ENSP00000421681|ensembl:ENST00000678714|ensembl:ENSP00000504221|ensembl:ENST00000312087|ensembl:ENSP00000308780|ensembl:ENST00000353275|refseq:NP_001035889.1|refseq:NP_015627.1|refseq:NP_579877.1|refseq:XP_011511859.1|refseq:XP_011511862.1|refseq:NP_579878.1|refseq:NP_579889.1|refseq:NP_579890.1|refseq:XP_005248058.1|refseq:XP_005248062.1|ensembl:ENSG00000109685(gene)|ensembl:ENST00000382891(transcript)|ensembl:ENST00000382892(transcript)|ensembl:ENST00000382895(transcript)|ensembl:ENST00000508803(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003289"(atrial septum primum morphogenesis)|go:"GO:0003290"(atrial septum secundum morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0060348"(bone development)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000313(PWWP)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR006560(AWS)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036910|interpro:IPR041306|mint:O96028|rcsb pdb:5LSU|rcsb pdb:5VC8|rcsb pdb:6UE6|rcsb pdb:6XCG|rcsb pdb:7CRO|rcsb pdb:7LMT|rcsb pdb:7MDN|reactome:R-HSA-3214841|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|refseq:XP_006713977.1|refseq:XP_016864076.1|refseq:XP_016864077.1|dip:DIP-57224N refseq:NP_002956.1|rcsb pdb:1XK4|rcsb pdb:4GGF|rcsb pdb:4XJK|rcsb pdb:5I8N|rcsb pdb:5W1F|rcsb pdb:6DS2|reactome:R-HSA-1236974|reactome:R-HSA-166058|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5668599|reactome:R-HSA-5686938|reactome:R-HSA-6798695|reactome:R-HSA-6799990|ensembl:ENSG00000163220(gene)|ensembl:ENST00000368738(transcript)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0002544"(chronic inflammatory response)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008017"(microtubule binding)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035662"(Toll-like receptor 4 binding)|go:"GO:0035821"(modulation of process of another organism)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0045087"(innate immune response)|go:"GO:0045113"(regulation of integrin biosynthetic process)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050544"(arachidonic acid binding)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050786"(RAGE receptor binding)|go:"GO:0050832"(defense response to fungus)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070488"(neutrophil aggregation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|mint:P06702|rcsb pdb:1IRJ|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014002"(astrocyte development)|go:"GO:0016209"(antioxidant activity)|go:"GO:0018119"(peptidyl-cysteine S-nitrosylation)|go:"GO:0030054"(cell junction)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032119"(sequestering of zinc ion)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035425"(autocrine signaling)|go:"GO:0035606"(peptidyl-cysteine S-trans-nitrosylation)|dip:DIP-1166N - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:uqzt7OSAe3MVGdh7z33m/zM/w4w9606 rogid:IGnX4DSnv8xMr5pY4T7X7vYos5A9606 rigid:0Ma0qTPLbtz9RotEjP18QWARgs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O96028 uniprotkb:O60825 intact:EBI-2693298|uniprotkb:A2A2T3|uniprotkb:A2A2T4|uniprotkb:A7MCZ1|uniprotkb:O96031|uniprotkb:Q4VBY8|uniprotkb:Q672J1|uniprotkb:Q6IS00|uniprotkb:Q86V01|uniprotkb:Q9BZB4|uniprotkb:Q9UI92|uniprotkb:Q9UPR2|intact:EBI-3438110|uniprotkb:D3DVQ2|uniprotkb:A2A2T2|intact:EBI-28971215|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENSP00000423972 intact:EBI-764425|uniprotkb:O60824|uniprotkb:Q5VVQ4|uniprotkb:Q9H3P1|uniprotkb:Q5VVQ3|ensembl:ENSP00000356047 psi-mi:nsd2_human(display_long)|uniprotkb:NSD2(gene name)|psi-mi:NSD2(display_short)|uniprotkb:KIAA1090(gene name synonym)|uniprotkb:MMSET(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Protein trithorax-5(gene name synonym)|uniprotkb:TRX5(gene name synonym)|uniprotkb:WHSC1(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein(gene name synonym) psi-mi:f262_human(display_long)|uniprotkb:6PF-2-K/Fru-2,6-P2ase heart-type isozyme(gene name synonym)|uniprotkb:PFKFB2(gene name)|psi-mi:PFKFB2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486814|imex:IM-26985-159 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000329167|ensembl:ENST00000382888|ensembl:ENSP00000372344|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENST00000398261|ensembl:ENSP00000381311|ensembl:ENST00000420906|ensembl:ENSP00000399251|ensembl:ENST00000503128|ensembl:ENSP00000425761|ensembl:ENSP00000423972|ensembl:ENST00000514045|ensembl:ENSP00000421681|ensembl:ENST00000678714|ensembl:ENSP00000504221|ensembl:ENST00000312087|ensembl:ENSP00000308780|ensembl:ENST00000353275|refseq:NP_001035889.1|refseq:NP_015627.1|refseq:NP_579877.1|refseq:XP_011511859.1|refseq:XP_011511862.1|refseq:NP_579878.1|refseq:NP_579889.1|refseq:NP_579890.1|refseq:XP_005248058.1|refseq:XP_005248062.1|ensembl:ENSG00000109685(gene)|ensembl:ENST00000382891(transcript)|ensembl:ENST00000382892(transcript)|ensembl:ENST00000382895(transcript)|ensembl:ENST00000508803(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003289"(atrial septum primum morphogenesis)|go:"GO:0003290"(atrial septum secundum morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0060348"(bone development)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000313(PWWP)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR006560(AWS)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036910|interpro:IPR041306|mint:O96028|rcsb pdb:5LSU|rcsb pdb:5VC8|rcsb pdb:6UE6|rcsb pdb:6XCG|rcsb pdb:7CRO|rcsb pdb:7LMT|rcsb pdb:7MDN|reactome:R-HSA-3214841|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|refseq:XP_006713977.1|refseq:XP_016864076.1|refseq:XP_016864077.1|dip:DIP-57224N refseq:NP_001018063.1|refseq:NP_006203.2|ensembl:ENSG00000123836(gene)|ensembl:ENST00000367080(transcript)|go:"GO:0003873"(6-phosphofructo-2-kinase activity)|go:"GO:0004331"(fructose-2,6-bisphosphate 2-phosphatase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006003"(fructose 2,6-bisphosphate metabolic process)|go:"GO:0006007"(glucose catabolic process)|go:"GO:0006089"(lactate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0009749"(response to glucose)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032024"(positive regulation of insulin secretion)|go:"GO:0033133"(positive regulation of glucokinase activity)|interpro:IPR001345(Phosphoglycerate/bisphosphoglycerate mutase)|interpro:IPR003094(Fructose-2,6-bisphosphatase)|interpro:IPR013078(Phosphoglycerate mutase)|interpro:IPR013079(6-phosphofructo-2-kinase)|interpro:IPR027417|interpro:IPR029033|mint:O60825|rcsb pdb:5HTK|reactome:R-HSA-9634600 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:uqzt7OSAe3MVGdh7z33m/zM/w4w9606 rogid:VAIXM3xzM91KrxL92RdTLkqVcaM9606 rigid:0Ma0qTPLbtz9RotEjP18QWARgs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O96028 uniprotkb:Q99523 intact:EBI-2693298|uniprotkb:A2A2T3|uniprotkb:A2A2T4|uniprotkb:A7MCZ1|uniprotkb:O96031|uniprotkb:Q4VBY8|uniprotkb:Q672J1|uniprotkb:Q6IS00|uniprotkb:Q86V01|uniprotkb:Q9BZB4|uniprotkb:Q9UI92|uniprotkb:Q9UPR2|intact:EBI-3438110|uniprotkb:D3DVQ2|uniprotkb:A2A2T2|intact:EBI-28971215|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENSP00000423972 intact:EBI-1057058|uniprotkb:Q8IZ49|uniprotkb:C0JYZ0|uniprotkb:B4DWI3|ensembl:ENSP00000256637 psi-mi:nsd2_human(display_long)|uniprotkb:NSD2(gene name)|psi-mi:NSD2(display_short)|uniprotkb:KIAA1090(gene name synonym)|uniprotkb:MMSET(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Protein trithorax-5(gene name synonym)|uniprotkb:TRX5(gene name synonym)|uniprotkb:WHSC1(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein(gene name synonym) psi-mi:sort_human(display_long)|uniprotkb:SORT1(gene name)|psi-mi:SORT1(display_short)|uniprotkb:Neurotensin receptor 3(gene name synonym)|uniprotkb:Glycoprotein 95(gene name synonym)|uniprotkb:100 kDa NT receptor(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486814|imex:IM-26985-159 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000329167|ensembl:ENST00000382888|ensembl:ENSP00000372344|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENST00000398261|ensembl:ENSP00000381311|ensembl:ENST00000420906|ensembl:ENSP00000399251|ensembl:ENST00000503128|ensembl:ENSP00000425761|ensembl:ENSP00000423972|ensembl:ENST00000514045|ensembl:ENSP00000421681|ensembl:ENST00000678714|ensembl:ENSP00000504221|ensembl:ENST00000312087|ensembl:ENSP00000308780|ensembl:ENST00000353275|refseq:NP_001035889.1|refseq:NP_015627.1|refseq:NP_579877.1|refseq:XP_011511859.1|refseq:XP_011511862.1|refseq:NP_579878.1|refseq:NP_579889.1|refseq:NP_579890.1|refseq:XP_005248058.1|refseq:XP_005248062.1|ensembl:ENSG00000109685(gene)|ensembl:ENST00000382891(transcript)|ensembl:ENST00000382892(transcript)|ensembl:ENST00000382895(transcript)|ensembl:ENST00000508803(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003289"(atrial septum primum morphogenesis)|go:"GO:0003290"(atrial septum secundum morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0060348"(bone development)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000313(PWWP)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR006560(AWS)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036910|interpro:IPR041306|mint:O96028|rcsb pdb:5LSU|rcsb pdb:5VC8|rcsb pdb:6UE6|rcsb pdb:6XCG|rcsb pdb:7CRO|rcsb pdb:7LMT|rcsb pdb:7MDN|reactome:R-HSA-3214841|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|refseq:XP_006713977.1|refseq:XP_016864076.1|refseq:XP_016864077.1|dip:DIP-57224N refseq:NP_001192157.1|refseq:NP_002950.3|ensembl:ENSG00000134243(gene)|ensembl:ENST00000256637(transcript)|go:"GO:0001503"(ossification)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005769"(early endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007218"(neuropeptide signaling pathway)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010465"(nerve growth factor receptor activity)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0014902"(myotube differentiation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0019899"(enzyme binding)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030379"(neurotensin receptor activity, non-G protein-coupled)|go:"GO:0030425"(dendrite)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0046323"(glucose import)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0048406"(nerve growth factor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051005"(negative regulation of lipoprotein lipase activity)|go:"GO:0090160"(Golgi to lysosome transport)|go:"GO:1904037"(positive regulation of epithelial cell apoptotic process)|go:"GO:1905394"(retromer complex binding)|interpro:IPR006581(VPS10)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR031777|interpro:IPR031778|mint:Q99523|rcsb pdb:3F6K|rcsb pdb:3G2U|rcsb pdb:3G2V|rcsb pdb:4MSL|rcsb pdb:4N7E|rcsb pdb:4PO7|rcsb pdb:5MRH|rcsb pdb:5MRI|rcsb pdb:6EHO|rcsb pdb:6X3L|rcsb pdb:6X48|rcsb pdb:6X4H|reactome:R-HSA-432722|go:"GO:0032868"(response to insulin)|dip:DIP-41798N - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:uqzt7OSAe3MVGdh7z33m/zM/w4w9606 rogid:h/+2jen/dw+5leVis906F7iBs/A9606 rigid:0Ma0qTPLbtz9RotEjP18QWARgs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O96028 uniprotkb:P25311 intact:EBI-2693298|uniprotkb:A2A2T3|uniprotkb:A2A2T4|uniprotkb:A7MCZ1|uniprotkb:O96031|uniprotkb:Q4VBY8|uniprotkb:Q672J1|uniprotkb:Q6IS00|uniprotkb:Q86V01|uniprotkb:Q9BZB4|uniprotkb:Q9UI92|uniprotkb:Q9UPR2|intact:EBI-3438110|uniprotkb:D3DVQ2|uniprotkb:A2A2T2|intact:EBI-28971215|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENSP00000423972 intact:EBI-2513837|ensembl:ENSP00000292401|uniprotkb:Q5XKQ4|uniprotkb:O60386|uniprotkb:Q8N4N0|uniprotkb:D6W5T8 psi-mi:nsd2_human(display_long)|uniprotkb:NSD2(gene name)|psi-mi:NSD2(display_short)|uniprotkb:KIAA1090(gene name synonym)|uniprotkb:MMSET(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Protein trithorax-5(gene name synonym)|uniprotkb:TRX5(gene name synonym)|uniprotkb:WHSC1(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein(gene name synonym) psi-mi:za2g_human(display_long)|uniprotkb:AZGP1(gene name)|psi-mi:AZGP1(display_short)|uniprotkb:ZAG(gene name synonym)|uniprotkb:ZNGP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486814|imex:IM-26985-159 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000329167|ensembl:ENST00000382888|ensembl:ENSP00000372344|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENST00000398261|ensembl:ENSP00000381311|ensembl:ENST00000420906|ensembl:ENSP00000399251|ensembl:ENST00000503128|ensembl:ENSP00000425761|ensembl:ENSP00000423972|ensembl:ENST00000514045|ensembl:ENSP00000421681|ensembl:ENST00000678714|ensembl:ENSP00000504221|ensembl:ENST00000312087|ensembl:ENSP00000308780|ensembl:ENST00000353275|refseq:NP_001035889.1|refseq:NP_015627.1|refseq:NP_579877.1|refseq:XP_011511859.1|refseq:XP_011511862.1|refseq:NP_579878.1|refseq:NP_579889.1|refseq:NP_579890.1|refseq:XP_005248058.1|refseq:XP_005248062.1|ensembl:ENSG00000109685(gene)|ensembl:ENST00000382891(transcript)|ensembl:ENST00000382892(transcript)|ensembl:ENST00000382895(transcript)|ensembl:ENST00000508803(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003289"(atrial septum primum morphogenesis)|go:"GO:0003290"(atrial septum secundum morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0060348"(bone development)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000313(PWWP)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR006560(AWS)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036910|interpro:IPR041306|mint:O96028|rcsb pdb:5LSU|rcsb pdb:5VC8|rcsb pdb:6UE6|rcsb pdb:6XCG|rcsb pdb:7CRO|rcsb pdb:7LMT|rcsb pdb:7MDN|reactome:R-HSA-3214841|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|refseq:XP_006713977.1|refseq:XP_016864076.1|refseq:XP_016864077.1|dip:DIP-57224N ensembl:ENSG00000160862(gene)|ensembl:ENST00000292401(transcript)|go:"GO:0001580"(detection of chemical stimulus involved in sensory perception of bitter taste)|go:"GO:0001895"(retina homeostasis)|go:"GO:0002476"(antigen processing and presentation of endogenous peptide antigen via MHC class Ib)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0007155"(cell adhesion)|go:"GO:0008285"(negative regulation of cell population proliferation)|interpro:IPR036179|interpro:IPR037055|mint:P25311|rcsb pdb:1T7V|rcsb pdb:1T7W|rcsb pdb:1T7X|rcsb pdb:1T7Y|rcsb pdb:1T7Z|rcsb pdb:1T80|rcsb pdb:1ZAG|rcsb pdb:3ES6|rcsb pdb:6R2U|reactome:R-HSA-5223345|go:"GO:0008320"(protein transmembrane transporter activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001039(MHC class I, alpha chain, alpha1 and alpha2)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR011161(MHC class I-like antigen recognition)|interpro:IPR011162(MHC classes I and II-like antigen recognition)|interpro:IPR013783(Immunoglobulin-like fold)|refseq:NP_001176.1 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:uqzt7OSAe3MVGdh7z33m/zM/w4w9606 rogid:3Fp6qALNiZRqsI8Kh2lTQ9IMYek9606 rigid:0Ma0qTPLbtz9RotEjP18QWARgs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O96028 uniprotkb:Q16777 intact:EBI-2693298|uniprotkb:A2A2T3|uniprotkb:A2A2T4|uniprotkb:A7MCZ1|uniprotkb:O96031|uniprotkb:Q4VBY8|uniprotkb:Q672J1|uniprotkb:Q6IS00|uniprotkb:Q86V01|uniprotkb:Q9BZB4|uniprotkb:Q9UI92|uniprotkb:Q9UPR2|intact:EBI-3438110|uniprotkb:D3DVQ2|uniprotkb:A2A2T2|intact:EBI-28971215|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENSP00000423972 intact:EBI-5325566|ensembl:ENSP00000332194|uniprotkb:Q6DRA7|uniprotkb:Q8IUE5 psi-mi:nsd2_human(display_long)|uniprotkb:NSD2(gene name)|psi-mi:NSD2(display_short)|uniprotkb:KIAA1090(gene name synonym)|uniprotkb:MMSET(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Protein trithorax-5(gene name synonym)|uniprotkb:TRX5(gene name synonym)|uniprotkb:WHSC1(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein(gene name synonym) psi-mi:h2a2c_human(display_long)|uniprotkb:H2AC20(gene name)|psi-mi:H2AC20(display_short)|uniprotkb:H2A-clustered histone 20(gene name synonym)|uniprotkb:H2AFQ(gene name synonym)|uniprotkb:HIST2H2AC(gene name synonym)|uniprotkb:Histone H2A-GL101(gene name synonym)|uniprotkb:Histone H2A/q(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486814|imex:IM-26985-159 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000329167|ensembl:ENST00000382888|ensembl:ENSP00000372344|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENST00000398261|ensembl:ENSP00000381311|ensembl:ENST00000420906|ensembl:ENSP00000399251|ensembl:ENST00000503128|ensembl:ENSP00000425761|ensembl:ENSP00000423972|ensembl:ENST00000514045|ensembl:ENSP00000421681|ensembl:ENST00000678714|ensembl:ENSP00000504221|ensembl:ENST00000312087|ensembl:ENSP00000308780|ensembl:ENST00000353275|refseq:NP_001035889.1|refseq:NP_015627.1|refseq:NP_579877.1|refseq:XP_011511859.1|refseq:XP_011511862.1|refseq:NP_579878.1|refseq:NP_579889.1|refseq:NP_579890.1|refseq:XP_005248058.1|refseq:XP_005248062.1|ensembl:ENSG00000109685(gene)|ensembl:ENST00000382891(transcript)|ensembl:ENST00000382892(transcript)|ensembl:ENST00000382895(transcript)|ensembl:ENST00000508803(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003289"(atrial septum primum morphogenesis)|go:"GO:0003290"(atrial septum secundum morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0060348"(bone development)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000313(PWWP)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR006560(AWS)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036910|interpro:IPR041306|mint:O96028|rcsb pdb:5LSU|rcsb pdb:5VC8|rcsb pdb:6UE6|rcsb pdb:6XCG|rcsb pdb:7CRO|rcsb pdb:7LMT|rcsb pdb:7MDN|reactome:R-HSA-3214841|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|refseq:XP_006713977.1|refseq:XP_016864076.1|refseq:XP_016864077.1|dip:DIP-57224N reactome:R-HSA-5689880|reactome:R-HSA-5689901|reactome:R-HSA-606279|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|reactome:R-HSA-5689603|ensembl:ENSG00000184260(gene)|ensembl:ENST00000331380(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0006342"|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:Q16777|rcsb pdb:6Y5E|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|refseq:NP_003508.1 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:uqzt7OSAe3MVGdh7z33m/zM/w4w9606 rogid:Wejrpp9wK3GvA4ahJDVyEH+cwlQ9606 rigid:0Ma0qTPLbtz9RotEjP18QWARgs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O96028 uniprotkb:P00450 intact:EBI-2693298|uniprotkb:A2A2T3|uniprotkb:A2A2T4|uniprotkb:A7MCZ1|uniprotkb:O96031|uniprotkb:Q4VBY8|uniprotkb:Q672J1|uniprotkb:Q6IS00|uniprotkb:Q86V01|uniprotkb:Q9BZB4|uniprotkb:Q9UI92|uniprotkb:Q9UPR2|intact:EBI-3438110|uniprotkb:D3DVQ2|uniprotkb:A2A2T2|intact:EBI-28971215|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENSP00000423972 intact:EBI-1220171|uniprotkb:Q14063|uniprotkb:Q2PP18|uniprotkb:Q9UKS4|ensembl:ENSP00000264613 psi-mi:nsd2_human(display_long)|uniprotkb:NSD2(gene name)|psi-mi:NSD2(display_short)|uniprotkb:KIAA1090(gene name synonym)|uniprotkb:MMSET(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Protein trithorax-5(gene name synonym)|uniprotkb:TRX5(gene name synonym)|uniprotkb:WHSC1(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein(gene name synonym) psi-mi:ceru_human(display_long)|uniprotkb:CP(gene name)|psi-mi:CP(display_short)|uniprotkb:Ferroxidase(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486814|imex:IM-26985-159 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000329167|ensembl:ENST00000382888|ensembl:ENSP00000372344|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENST00000398261|ensembl:ENSP00000381311|ensembl:ENST00000420906|ensembl:ENSP00000399251|ensembl:ENST00000503128|ensembl:ENSP00000425761|ensembl:ENSP00000423972|ensembl:ENST00000514045|ensembl:ENSP00000421681|ensembl:ENST00000678714|ensembl:ENSP00000504221|ensembl:ENST00000312087|ensembl:ENSP00000308780|ensembl:ENST00000353275|refseq:NP_001035889.1|refseq:NP_015627.1|refseq:NP_579877.1|refseq:XP_011511859.1|refseq:XP_011511862.1|refseq:NP_579878.1|refseq:NP_579889.1|refseq:NP_579890.1|refseq:XP_005248058.1|refseq:XP_005248062.1|ensembl:ENSG00000109685(gene)|ensembl:ENST00000382891(transcript)|ensembl:ENST00000382892(transcript)|ensembl:ENST00000382895(transcript)|ensembl:ENST00000508803(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003289"(atrial septum primum morphogenesis)|go:"GO:0003290"(atrial septum secundum morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0060348"(bone development)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000313(PWWP)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR006560(AWS)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036910|interpro:IPR041306|mint:O96028|rcsb pdb:5LSU|rcsb pdb:5VC8|rcsb pdb:6UE6|rcsb pdb:6XCG|rcsb pdb:7CRO|rcsb pdb:7LMT|rcsb pdb:7MDN|reactome:R-HSA-3214841|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|refseq:XP_006713977.1|refseq:XP_016864076.1|refseq:XP_016864077.1|dip:DIP-57224N refseq:NP_000087.1|ensembl:ENSG00000047457(gene)|ensembl:ENST00000264613(transcript)|go:"GO:0004322"(ferroxidase activity)|go:"GO:0005507"(copper ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0006825"(copper ion transport)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR001117(Multicopper oxidase, type 1)|interpro:IPR002355(Multicopper oxidase, copper-binding site)|interpro:IPR008972(Cupredoxin)|interpro:IPR011706(Multicopper oxidase, type 2)|interpro:IPR011707(Multicopper oxidase, type 3)|interpro:IPR033138|mint:P00450|rcsb pdb:1KCW|rcsb pdb:2J5W|rcsb pdb:4EJX|rcsb pdb:4ENZ|reactome:R-HSA-381426|reactome:R-HSA-425410|reactome:R-HSA-5619049|reactome:R-HSA-5619060|reactome:R-HSA-8957275|reactome:R-HSA-917937 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:uqzt7OSAe3MVGdh7z33m/zM/w4w9606 rogid:bPuhUo8h0DvtcwLufTOOHxrl9NI9606 rigid:0Ma0qTPLbtz9RotEjP18QWARgs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O96028 uniprotkb:P02774 intact:EBI-2693298|uniprotkb:A2A2T3|uniprotkb:A2A2T4|uniprotkb:A7MCZ1|uniprotkb:O96031|uniprotkb:Q4VBY8|uniprotkb:Q672J1|uniprotkb:Q6IS00|uniprotkb:Q86V01|uniprotkb:Q9BZB4|uniprotkb:Q9UI92|uniprotkb:Q9UPR2|intact:EBI-3438110|uniprotkb:D3DVQ2|uniprotkb:A2A2T2|intact:EBI-28971215|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENSP00000423972 intact:EBI-715425|uniprotkb:Q16309|uniprotkb:Q16310|uniprotkb:B4DPP2|uniprotkb:Q53F31|uniprotkb:Q6GTG1|ensembl:ENSP00000273951|uniprotkb:D6RAK8 psi-mi:nsd2_human(display_long)|uniprotkb:NSD2(gene name)|psi-mi:NSD2(display_short)|uniprotkb:KIAA1090(gene name synonym)|uniprotkb:MMSET(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Protein trithorax-5(gene name synonym)|uniprotkb:TRX5(gene name synonym)|uniprotkb:WHSC1(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein(gene name synonym) psi-mi:vtdb_human(display_long)|uniprotkb:Group-specific component(gene name synonym)|uniprotkb:Gc-globulin(gene name synonym)|uniprotkb:GC(gene name)|psi-mi:GC(display_short)|uniprotkb:Gc protein-derived macrophage activating factor(gene name synonym)|uniprotkb:Vitamin D-binding protein-macrophage activating factor(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486814|imex:IM-26985-159 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000329167|ensembl:ENST00000382888|ensembl:ENSP00000372344|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENST00000398261|ensembl:ENSP00000381311|ensembl:ENST00000420906|ensembl:ENSP00000399251|ensembl:ENST00000503128|ensembl:ENSP00000425761|ensembl:ENSP00000423972|ensembl:ENST00000514045|ensembl:ENSP00000421681|ensembl:ENST00000678714|ensembl:ENSP00000504221|ensembl:ENST00000312087|ensembl:ENSP00000308780|ensembl:ENST00000353275|refseq:NP_001035889.1|refseq:NP_015627.1|refseq:NP_579877.1|refseq:XP_011511859.1|refseq:XP_011511862.1|refseq:NP_579878.1|refseq:NP_579889.1|refseq:NP_579890.1|refseq:XP_005248058.1|refseq:XP_005248062.1|ensembl:ENSG00000109685(gene)|ensembl:ENST00000382891(transcript)|ensembl:ENST00000382892(transcript)|ensembl:ENST00000382895(transcript)|ensembl:ENST00000508803(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003289"(atrial septum primum morphogenesis)|go:"GO:0003290"(atrial septum secundum morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0060348"(bone development)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000313(PWWP)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR006560(AWS)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036910|interpro:IPR041306|mint:O96028|rcsb pdb:5LSU|rcsb pdb:5VC8|rcsb pdb:6UE6|rcsb pdb:6XCG|rcsb pdb:7CRO|rcsb pdb:7LMT|rcsb pdb:7MDN|reactome:R-HSA-3214841|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|refseq:XP_006713977.1|refseq:XP_016864076.1|refseq:XP_016864077.1|dip:DIP-57224N refseq:NP_000574.2|refseq:NP_001191235.1|refseq:NP_001191236.1|ensembl:ENSG00000145321(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005499"(vitamin D binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042359"(vitamin D metabolic process)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0051180"(vitamin transport)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090482"(vitamin transmembrane transporter activity)|go:"GO:1902118"(calcidiol binding)|interpro:IPR000213(Vitamin D-binding protein)|interpro:IPR000264(Serum albumin)|interpro:IPR014760(Serum albumin, N-terminal)|interpro:IPR015247(Vitamin D binding protein, domain III)|interpro:IPR020857|interpro:IPR020858|mint:P02774|rcsb pdb:1J78|rcsb pdb:1J7E|rcsb pdb:1KW2|rcsb pdb:1KXP|rcsb pdb:1LOT|rcsb pdb:1MA9|reactome:R-HSA-196791|ensembl:ENST00000273951(transcript)|dip:DIP-17038N - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:uqzt7OSAe3MVGdh7z33m/zM/w4w9606 rogid:HqqTzgR6+bey6fQFLPpQQtp4rus9606 rigid:0Ma0qTPLbtz9RotEjP18QWARgs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O96028 uniprotkb:P02671 intact:EBI-2693298|uniprotkb:A2A2T3|uniprotkb:A2A2T4|uniprotkb:A7MCZ1|uniprotkb:O96031|uniprotkb:Q4VBY8|uniprotkb:Q672J1|uniprotkb:Q6IS00|uniprotkb:Q86V01|uniprotkb:Q9BZB4|uniprotkb:Q9UI92|uniprotkb:Q9UPR2|intact:EBI-3438110|uniprotkb:D3DVQ2|uniprotkb:A2A2T2|intact:EBI-28971215|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENSP00000423972 intact:EBI-348571|ensembl:ENSP00000498441|uniprotkb:Q9BX62|uniprotkb:Q9UCH2|uniprotkb:A8K3E4|uniprotkb:Q4QQH7|uniprotkb:D3DP14|uniprotkb:D3DP15 psi-mi:nsd2_human(display_long)|uniprotkb:NSD2(gene name)|psi-mi:NSD2(display_short)|uniprotkb:KIAA1090(gene name synonym)|uniprotkb:MMSET(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Protein trithorax-5(gene name synonym)|uniprotkb:TRX5(gene name synonym)|uniprotkb:WHSC1(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein(gene name synonym) psi-mi:fiba_human(display_long)|uniprotkb:FGA(gene name)|psi-mi:FGA(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486814|imex:IM-26985-159 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000329167|ensembl:ENST00000382888|ensembl:ENSP00000372344|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENST00000398261|ensembl:ENSP00000381311|ensembl:ENST00000420906|ensembl:ENSP00000399251|ensembl:ENST00000503128|ensembl:ENSP00000425761|ensembl:ENSP00000423972|ensembl:ENST00000514045|ensembl:ENSP00000421681|ensembl:ENST00000678714|ensembl:ENSP00000504221|ensembl:ENST00000312087|ensembl:ENSP00000308780|ensembl:ENST00000353275|refseq:NP_001035889.1|refseq:NP_015627.1|refseq:NP_579877.1|refseq:XP_011511859.1|refseq:XP_011511862.1|refseq:NP_579878.1|refseq:NP_579889.1|refseq:NP_579890.1|refseq:XP_005248058.1|refseq:XP_005248062.1|ensembl:ENSG00000109685(gene)|ensembl:ENST00000382891(transcript)|ensembl:ENST00000382892(transcript)|ensembl:ENST00000382895(transcript)|ensembl:ENST00000508803(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003289"(atrial septum primum morphogenesis)|go:"GO:0003290"(atrial septum secundum morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0060348"(bone development)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000313(PWWP)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR006560(AWS)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036910|interpro:IPR041306|mint:O96028|rcsb pdb:5LSU|rcsb pdb:5VC8|rcsb pdb:6UE6|rcsb pdb:6XCG|rcsb pdb:7CRO|rcsb pdb:7LMT|rcsb pdb:7MDN|reactome:R-HSA-3214841|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|refseq:XP_006713977.1|refseq:XP_016864076.1|refseq:XP_016864077.1|dip:DIP-57224N refseq:NP_000499.1|refseq:NP_068657.1|ensembl:ENSG00000171560(gene)|ensembl:ENST00000651975(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:1903561"(extracellular vesicle)|go:"GO:2000261"(negative regulation of blood coagulation, common pathway)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR012290(Fibrinogen, alpha/beta/gamma chain, coiled coil)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070527"(platelet aggregation)|go:"GO:0072377"(blood coagulation, common pathway)|interpro:IPR021996|interpro:IPR036056|interpro:IPR037579|mint:P02671|rcsb pdb:1BBR|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|rcsb pdb:1DM4|rcsb pdb:1FPH|rcsb pdb:1FZA|rcsb pdb:1FZB|go:"GO:0090277"(positive regulation of peptide hormone secretion)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|rcsb pdb:1FZC|rcsb pdb:1FZD|go:"GO:0031639"(plasminogen activation)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034622"|go:"GO:0042730"(fibrinolysis)|go:"GO:0043152"(induction of bacterial agglutination)|go:"GO:0045087"(innate immune response)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0046872"(metal ion binding)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051258"(protein polymerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:1FZF|rcsb pdb:1FZG|rcsb pdb:1LT9|rcsb pdb:1LTJ|rcsb pdb:1N86|rcsb pdb:1N8E|rcsb pdb:1RE3|rcsb pdb:1RE4|rcsb pdb:1RF0|rcsb pdb:1RF1|rcsb pdb:1YCP|rcsb pdb:2A45|rcsb pdb:2FFD|rcsb pdb:2H43|rcsb pdb:2HLO|rcsb pdb:2HOD|rcsb pdb:2HPC|rcsb pdb:2OYH|rcsb pdb:2OYI|rcsb pdb:2Q9I|rcsb pdb:2XNX|rcsb pdb:2XNY|rcsb pdb:2Z4E|rcsb pdb:3AT0|rcsb pdb:1FZE|rcsb pdb:3BVH|rcsb pdb:3E1I|rcsb pdb:3GHG|rcsb pdb:3H32|rcsb pdb:3HUS|rcsb pdb:4F27|rcsb pdb:5CFA|reactome:R-HSA-114608|reactome:R-HSA-1236974|reactome:R-HSA-5674135|reactome:R-HSA-140875|reactome:R-HSA-166058|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-5686938|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-8957275|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-977225|dip:DIP-29643N - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:uqzt7OSAe3MVGdh7z33m/zM/w4w9606 rogid:khlQGVpd+6qZLTrsT9KxlxgjMR09606 rigid:0Ma0qTPLbtz9RotEjP18QWARgs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O96028 uniprotkb:P0CG04 intact:EBI-2693298|uniprotkb:A2A2T3|uniprotkb:A2A2T4|uniprotkb:A7MCZ1|uniprotkb:O96031|uniprotkb:Q4VBY8|uniprotkb:Q672J1|uniprotkb:Q6IS00|uniprotkb:Q86V01|uniprotkb:Q9BZB4|uniprotkb:Q9UI92|uniprotkb:Q9UPR2|intact:EBI-3438110|uniprotkb:D3DVQ2|uniprotkb:A2A2T2|intact:EBI-28971215|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENSP00000423972 intact:EBI-1221063|uniprotkb:P80423|uniprotkb:A0M8Q4|uniprotkb:P01842|uniprotkb:A0A075B6K8 psi-mi:nsd2_human(display_long)|uniprotkb:NSD2(gene name)|psi-mi:NSD2(display_short)|uniprotkb:KIAA1090(gene name synonym)|uniprotkb:MMSET(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Protein trithorax-5(gene name synonym)|uniprotkb:TRX5(gene name synonym)|uniprotkb:WHSC1(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein(gene name synonym) psi-mi:iglc1_human(display_long)|uniprotkb:IGLC1(gene name)|psi-mi:IGLC1(display_short)|uniprotkb:Ig lambda chain C region MGC(gene name synonym)|uniprotkb:Ig lambda-1 chain C region(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486814|imex:IM-26985-159 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000329167|ensembl:ENST00000382888|ensembl:ENSP00000372344|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENST00000398261|ensembl:ENSP00000381311|ensembl:ENST00000420906|ensembl:ENSP00000399251|ensembl:ENST00000503128|ensembl:ENSP00000425761|ensembl:ENSP00000423972|ensembl:ENST00000514045|ensembl:ENSP00000421681|ensembl:ENST00000678714|ensembl:ENSP00000504221|ensembl:ENST00000312087|ensembl:ENSP00000308780|ensembl:ENST00000353275|refseq:NP_001035889.1|refseq:NP_015627.1|refseq:NP_579877.1|refseq:XP_011511859.1|refseq:XP_011511862.1|refseq:NP_579878.1|refseq:NP_579889.1|refseq:NP_579890.1|refseq:XP_005248058.1|refseq:XP_005248062.1|ensembl:ENSG00000109685(gene)|ensembl:ENST00000382891(transcript)|ensembl:ENST00000382892(transcript)|ensembl:ENST00000382895(transcript)|ensembl:ENST00000508803(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003289"(atrial septum primum morphogenesis)|go:"GO:0003290"(atrial septum secundum morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0060348"(bone development)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000313(PWWP)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR006560(AWS)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036910|interpro:IPR041306|mint:O96028|rcsb pdb:5LSU|rcsb pdb:5VC8|rcsb pdb:6UE6|rcsb pdb:6XCG|rcsb pdb:7CRO|rcsb pdb:7LMT|rcsb pdb:7MDN|reactome:R-HSA-3214841|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|refseq:XP_006713977.1|refseq:XP_016864076.1|refseq:XP_016864077.1|dip:DIP-57224N interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR003006(Immunoglobulin/major histocompatibility complex, conserved site)|interpro:IPR003597(Immunoglobulin C1-set)|mint:P0CG04|interpro:IPR036179|go:"GO:0003823"(antigen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0006910"(phagocytosis, recognition)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0006955"(immune response)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0034987"(immunoglobulin receptor binding)|go:"GO:0042571"(immunoglobulin complex, circulating)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0050871"(positive regulation of B cell activation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|rcsb pdb:1ZVO|rcsb pdb:2FB4|rcsb pdb:2IG2|reactome:R-HSA-166663|reactome:R-HSA-173623|reactome:R-HSA-198933|reactome:R-HSA-202733|reactome:R-HSA-2029481|reactome:R-HSA-2029482|reactome:R-HSA-2029485|reactome:R-HSA-2168880|reactome:R-HSA-2454202|reactome:R-HSA-2730905|reactome:R-HSA-2871796|reactome:R-HSA-2871809|go:"GO:0045087"(innate immune response)|reactome:R-HSA-2871837|reactome:R-HSA-5690714|reactome:R-HSA-9664422|reactome:R-HSA-977606|reactome:R-HSA-983695|reactome:R-HSA-9664323 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:uqzt7OSAe3MVGdh7z33m/zM/w4w9606 rogid:OOdxBXPI2Jzf9HxurFZjk3/L1DM9606 rigid:0Ma0qTPLbtz9RotEjP18QWARgs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O96028 uniprotkb:P02675 intact:EBI-2693298|uniprotkb:A2A2T3|uniprotkb:A2A2T4|uniprotkb:A7MCZ1|uniprotkb:O96031|uniprotkb:Q4VBY8|uniprotkb:Q672J1|uniprotkb:Q6IS00|uniprotkb:Q86V01|uniprotkb:Q9BZB4|uniprotkb:Q9UI92|uniprotkb:Q9UPR2|intact:EBI-3438110|uniprotkb:D3DVQ2|uniprotkb:A2A2T2|intact:EBI-28971215|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENSP00000423972 intact:EBI-1034445|uniprotkb:A0JLR9|uniprotkb:Q32Q65|uniprotkb:Q3KPF2|uniprotkb:B2R7G3|ensembl:ENSP00000306099 psi-mi:nsd2_human(display_long)|uniprotkb:NSD2(gene name)|psi-mi:NSD2(display_short)|uniprotkb:KIAA1090(gene name synonym)|uniprotkb:MMSET(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Protein trithorax-5(gene name synonym)|uniprotkb:TRX5(gene name synonym)|uniprotkb:WHSC1(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein(gene name synonym) psi-mi:fibb_human(display_long)|uniprotkb:FGB(gene name)|psi-mi:FGB(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486814|imex:IM-26985-159 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000329167|ensembl:ENST00000382888|ensembl:ENSP00000372344|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENST00000398261|ensembl:ENSP00000381311|ensembl:ENST00000420906|ensembl:ENSP00000399251|ensembl:ENST00000503128|ensembl:ENSP00000425761|ensembl:ENSP00000423972|ensembl:ENST00000514045|ensembl:ENSP00000421681|ensembl:ENST00000678714|ensembl:ENSP00000504221|ensembl:ENST00000312087|ensembl:ENSP00000308780|ensembl:ENST00000353275|refseq:NP_001035889.1|refseq:NP_015627.1|refseq:NP_579877.1|refseq:XP_011511859.1|refseq:XP_011511862.1|refseq:NP_579878.1|refseq:NP_579889.1|refseq:NP_579890.1|refseq:XP_005248058.1|refseq:XP_005248062.1|ensembl:ENSG00000109685(gene)|ensembl:ENST00000382891(transcript)|ensembl:ENST00000382892(transcript)|ensembl:ENST00000382895(transcript)|ensembl:ENST00000508803(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003289"(atrial septum primum morphogenesis)|go:"GO:0003290"(atrial septum secundum morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0060348"(bone development)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000313(PWWP)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR006560(AWS)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036910|interpro:IPR041306|mint:O96028|rcsb pdb:5LSU|rcsb pdb:5VC8|rcsb pdb:6UE6|rcsb pdb:6XCG|rcsb pdb:7CRO|rcsb pdb:7LMT|rcsb pdb:7MDN|reactome:R-HSA-3214841|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|refseq:XP_006713977.1|refseq:XP_016864076.1|refseq:XP_016864077.1|dip:DIP-57224N refseq:NP_001171670.1|refseq:NP_005132.2|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031639"(plasminogen activation)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034622"|go:"GO:0042730"(fibrinolysis)|go:"GO:0043152"(induction of bacterial agglutination)|go:"GO:0044320"(cellular response to leptin stimulus)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045921"(positive regulation of exocytosis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051087"(chaperone binding)|go:"GO:0051258"(protein polymerization)|go:"GO:0051592"(response to calcium ion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0090277"(positive regulation of peptide hormone secretion)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902042"(negative regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903561"(extracellular vesicle)|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR002181(Fibrinogen, alpha/beta/gamma chain, C-terminal globular)|interpro:IPR012290(Fibrinogen, alpha/beta/gamma chain, coiled coil)|interpro:IPR014716(Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1)|interpro:IPR020837|interpro:IPR036056|interpro:IPR037580|mint:P02675|rcsb pdb:1FZA|rcsb pdb:1FZB|rcsb pdb:1FZC|rcsb pdb:1FZE|rcsb pdb:1FZF|rcsb pdb:1FZG|rcsb pdb:1LT9|rcsb pdb:1LTJ|rcsb pdb:1N86|rcsb pdb:1N8E|rcsb pdb:1RE3|rcsb pdb:1RE4|rcsb pdb:1RF0|rcsb pdb:1RF1|rcsb pdb:2A45|rcsb pdb:2FFD|rcsb pdb:2H43|rcsb pdb:2HLO|rcsb pdb:2HOD|rcsb pdb:2HPC|rcsb pdb:2OYH|rcsb pdb:2OYI|rcsb pdb:2Q9I|rcsb pdb:2XNX|rcsb pdb:2XNY|rcsb pdb:2Z4E|rcsb pdb:3BVH|rcsb pdb:3E1I|rcsb pdb:3GHG|rcsb pdb:3H32|rcsb pdb:3HUS|rcsb pdb:6ATZ|rcsb pdb:6BIJ|rcsb pdb:6BIL|rcsb pdb:6V0Y|rcsb pdb:6V13|rcsb pdb:6V15|rcsb pdb:6V18|rcsb pdb:6V19|rcsb pdb:6V1A|reactome:R-HSA-114608|reactome:R-HSA-1236974|reactome:R-HSA-140875|reactome:R-HSA-166058|reactome:R-HSA-216083|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-5602498|reactome:R-HSA-5603041|reactome:R-HSA-5674135|reactome:R-HSA-5686938|reactome:R-HSA-6802946|ensembl:ENSG00000171564(gene)|ensembl:ENST00000302068(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-6802952|reactome:R-HSA-6802948|dip:DIP-385N - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:uqzt7OSAe3MVGdh7z33m/zM/w4w9606 rogid:cbcOBnZB/W/Y7eE/IxM2HfZHpK49606 rigid:0Ma0qTPLbtz9RotEjP18QWARgs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O96028 uniprotkb:P01011 intact:EBI-2693298|uniprotkb:A2A2T3|uniprotkb:A2A2T4|uniprotkb:A7MCZ1|uniprotkb:O96031|uniprotkb:Q4VBY8|uniprotkb:Q672J1|uniprotkb:Q6IS00|uniprotkb:Q86V01|uniprotkb:Q9BZB4|uniprotkb:Q9UI92|uniprotkb:Q9UPR2|intact:EBI-3438110|uniprotkb:D3DVQ2|uniprotkb:A2A2T2|intact:EBI-28971215|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENSP00000423972 intact:EBI-296557|uniprotkb:Q9UC47|uniprotkb:Q13703|uniprotkb:Q2TU87|uniprotkb:Q2TU88|uniprotkb:Q59GP9|uniprotkb:Q6LBY8|uniprotkb:Q6LDT7|uniprotkb:Q6NSC9|uniprotkb:Q8N177|uniprotkb:Q96DW8|uniprotkb:Q9UNU9|uniprotkb:B3KVQ7|ensembl:ENSP00000376793|ensembl:ENSP00000376795|ensembl:ENSP00000450540 psi-mi:nsd2_human(display_long)|uniprotkb:NSD2(gene name)|psi-mi:NSD2(display_short)|uniprotkb:KIAA1090(gene name synonym)|uniprotkb:MMSET(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Protein trithorax-5(gene name synonym)|uniprotkb:TRX5(gene name synonym)|uniprotkb:WHSC1(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein(gene name synonym) psi-mi:aact_human(display_long)|uniprotkb:Cell growth-inhibiting gene 24/25 protein(gene name synonym)|uniprotkb:SERPINA3(gene name)|psi-mi:SERPINA3(display_short)|uniprotkb:AACT(gene name synonym)|uniprotkb:GIG24(orf name)|uniprotkb:GIG25(orf name)|uniprotkb:Serpin A3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486814|imex:IM-26985-159 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000329167|ensembl:ENST00000382888|ensembl:ENSP00000372344|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENST00000398261|ensembl:ENSP00000381311|ensembl:ENST00000420906|ensembl:ENSP00000399251|ensembl:ENST00000503128|ensembl:ENSP00000425761|ensembl:ENSP00000423972|ensembl:ENST00000514045|ensembl:ENSP00000421681|ensembl:ENST00000678714|ensembl:ENSP00000504221|ensembl:ENST00000312087|ensembl:ENSP00000308780|ensembl:ENST00000353275|refseq:NP_001035889.1|refseq:NP_015627.1|refseq:NP_579877.1|refseq:XP_011511859.1|refseq:XP_011511862.1|refseq:NP_579878.1|refseq:NP_579889.1|refseq:NP_579890.1|refseq:XP_005248058.1|refseq:XP_005248062.1|ensembl:ENSG00000109685(gene)|ensembl:ENST00000382891(transcript)|ensembl:ENST00000382892(transcript)|ensembl:ENST00000382895(transcript)|ensembl:ENST00000508803(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003289"(atrial septum primum morphogenesis)|go:"GO:0003290"(atrial septum secundum morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0060348"(bone development)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000313(PWWP)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR006560(AWS)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036910|interpro:IPR041306|mint:O96028|rcsb pdb:5LSU|rcsb pdb:5VC8|rcsb pdb:6UE6|rcsb pdb:6XCG|rcsb pdb:7CRO|rcsb pdb:7LMT|rcsb pdb:7MDN|reactome:R-HSA-3214841|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|refseq:XP_006713977.1|refseq:XP_016864076.1|refseq:XP_016864077.1|dip:DIP-57224N go:"GO:0006953"(acute-phase response)|refseq:NP_001076.2|ensembl:ENSG00000196136(gene)|ensembl:ENST00000393078(transcript)|ensembl:ENST00000393080(transcript)|ensembl:ENST00000467132(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|reactome:R-HSA-6798695|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0030277"(maintenance of gastrointestinal epithelium)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|interpro:IPR000215(Protease inhibitor I4, serpin)|go:"GO:0006954"(inflammatory response)|interpro:IPR023795|interpro:IPR023796|go:"GO:0010951"(negative regulation of endopeptidase activity)|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P01011|rcsb pdb:1AS4|rcsb pdb:1QMN|rcsb pdb:2ACH|rcsb pdb:3CAA|rcsb pdb:3DLW|rcsb pdb:4CAA|rcsb pdb:6HGE|reactome:R-HSA-114608 - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:uqzt7OSAe3MVGdh7z33m/zM/w4w9606 rogid:LTdrRsWwtOm8QvOWZ4h0SO8EuP09606 rigid:0Ma0qTPLbtz9RotEjP18QWARgs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O96028 uniprotkb:P10909 intact:EBI-2693298|uniprotkb:A2A2T3|uniprotkb:A2A2T4|uniprotkb:A7MCZ1|uniprotkb:O96031|uniprotkb:Q4VBY8|uniprotkb:Q672J1|uniprotkb:Q6IS00|uniprotkb:Q86V01|uniprotkb:Q9BZB4|uniprotkb:Q9UI92|uniprotkb:Q9UPR2|intact:EBI-3438110|uniprotkb:D3DVQ2|uniprotkb:A2A2T2|intact:EBI-28971215|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENSP00000423972 intact:EBI-1104674|uniprotkb:B3KSE6|uniprotkb:P11380|uniprotkb:P11381|uniprotkb:Q5HYC1|uniprotkb:Q7Z5B9|uniprotkb:B2R9Q1|uniprotkb:Q2TU75|ensembl:ENSP00000315130|ensembl:ENSP00000385419|ensembl:ENSP00000429620 psi-mi:nsd2_human(display_long)|uniprotkb:NSD2(gene name)|psi-mi:NSD2(display_short)|uniprotkb:KIAA1090(gene name synonym)|uniprotkb:MMSET(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Protein trithorax-5(gene name synonym)|uniprotkb:TRX5(gene name synonym)|uniprotkb:WHSC1(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein(gene name synonym) psi-mi:clus_human(display_long)|uniprotkb:CLU(gene name)|psi-mi:CLU(display_short)|uniprotkb:APOJ(gene name synonym)|uniprotkb:CLI(gene name synonym)|uniprotkb:KUB1(gene name synonym)|uniprotkb:Complement-associated protein SP-40,40(gene name synonym)|uniprotkb:Complement cytolysis inhibitor(gene name synonym)|uniprotkb:NA1/NA2(gene name synonym)|uniprotkb:Apolipoprotein J(gene name synonym)|uniprotkb:Testosterone-repressed prostate message 2(gene name synonym)|uniprotkb:Ku70-binding protein 1(gene name synonym)|uniprotkb:Aging-associated gene 4 protein(gene name synonym)|uniprotkb:AAG4(orf name)|uniprotkb:Sulfated glycoprotein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486814|imex:IM-26985-159 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000329167|ensembl:ENST00000382888|ensembl:ENSP00000372344|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENST00000398261|ensembl:ENSP00000381311|ensembl:ENST00000420906|ensembl:ENSP00000399251|ensembl:ENST00000503128|ensembl:ENSP00000425761|ensembl:ENSP00000423972|ensembl:ENST00000514045|ensembl:ENSP00000421681|ensembl:ENST00000678714|ensembl:ENSP00000504221|ensembl:ENST00000312087|ensembl:ENSP00000308780|ensembl:ENST00000353275|refseq:NP_001035889.1|refseq:NP_015627.1|refseq:NP_579877.1|refseq:XP_011511859.1|refseq:XP_011511862.1|refseq:NP_579878.1|refseq:NP_579889.1|refseq:NP_579890.1|refseq:XP_005248058.1|refseq:XP_005248062.1|ensembl:ENSG00000109685(gene)|ensembl:ENST00000382891(transcript)|ensembl:ENST00000382892(transcript)|ensembl:ENST00000382895(transcript)|ensembl:ENST00000508803(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003289"(atrial septum primum morphogenesis)|go:"GO:0003290"(atrial septum secundum morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0060348"(bone development)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000313(PWWP)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR006560(AWS)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036910|interpro:IPR041306|mint:O96028|rcsb pdb:5LSU|rcsb pdb:5VC8|rcsb pdb:6UE6|rcsb pdb:6XCG|rcsb pdb:7CRO|rcsb pdb:7LMT|rcsb pdb:7MDN|reactome:R-HSA-3214841|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|refseq:XP_006713977.1|refseq:XP_016864076.1|refseq:XP_016864077.1|dip:DIP-57224N go:"GO:0006629"(lipid metabolic process)|go:"GO:0006956"(complement activation)|go:"GO:0006958"(complement activation, classical pathway)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0017038"(protein import)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032286"(central nervous system myelin maintenance)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0005829"(cytosol)|ensembl:ENSG00000120885(gene)|ensembl:ENST00000316403(transcript)|ensembl:ENST00000405140(transcript)|ensembl:ENST00000523500(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001774"(microglial cell activation)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0002434"(immune complex clearance)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0034366"(spherical high-density lipoprotein particle)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042583"(chromaffin granule)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045202"(synapse)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048156"(tau protein binding)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0051788"(response to misfolded protein)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061518"(microglial cell proliferation)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0090201"(negative regulation of release of cytochrome c from mitochondria)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097418"(neurofibrillary tangle)|go:"GO:0097440"(apical dendrite)|go:"GO:0099020"(perinuclear endoplasmic reticulum lumen)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:1900221"(regulation of amyloid-beta clearance)|go:"GO:1901214"(regulation of neuron death)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902230"(negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902847"(regulation of neuronal signal transduction)|go:"GO:1902949"(positive regulation of tau-protein kinase activity)|go:"GO:1902998"(positive regulation of neurofibrillary tangle assembly)|go:"GO:1903573"(negative regulation of response to endoplasmic reticulum stress)|go:"GO:1905892"(negative regulation of cellular response to thapsigargin)|go:"GO:1905895"(negative regulation of cellular response to tunicamycin)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|go:"GO:1905908"(positive regulation of amyloid fibril formation)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR000753(Clusterin-like)|interpro:IPR016014(Clusterin, N-terminal)|interpro:IPR016015(Clusterin, C-terminal)|interpro:IPR016016(Clusterin)|interpro:IPR033986|mint:P10909|reactome:R-HSA-114608|reactome:R-HSA-166665|reactome:R-HSA-6803157|go:"GO:0060548"(negative regulation of cell death)|reactome:R-HSA-977606|refseq:NP_001822.3|dip:DIP-37546N - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:uqzt7OSAe3MVGdh7z33m/zM/w4w9606 rogid:qlCJp4zYTklC3YZNQvbLmZBiz4U9606 rigid:0Ma0qTPLbtz9RotEjP18QWARgs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O96028 uniprotkb:P02763 intact:EBI-2693298|uniprotkb:A2A2T3|uniprotkb:A2A2T4|uniprotkb:A7MCZ1|uniprotkb:O96031|uniprotkb:Q4VBY8|uniprotkb:Q672J1|uniprotkb:Q6IS00|uniprotkb:Q86V01|uniprotkb:Q9BZB4|uniprotkb:Q9UI92|uniprotkb:Q9UPR2|intact:EBI-3438110|uniprotkb:D3DVQ2|uniprotkb:A2A2T2|intact:EBI-28971215|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENSP00000423972 intact:EBI-976767|uniprotkb:Q8TC16|uniprotkb:B7ZKQ5|uniprotkb:Q5T539|ensembl:ENSP00000259396|uniprotkb:Q5U067 psi-mi:nsd2_human(display_long)|uniprotkb:NSD2(gene name)|psi-mi:NSD2(display_short)|uniprotkb:KIAA1090(gene name synonym)|uniprotkb:MMSET(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Protein trithorax-5(gene name synonym)|uniprotkb:TRX5(gene name synonym)|uniprotkb:WHSC1(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein(gene name synonym) psi-mi:a1ag1_human(display_long)|uniprotkb:Orosomucoid-1(gene name synonym)|uniprotkb:ORM1(gene name)|psi-mi:ORM1(display_short)|uniprotkb:AGP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486814|imex:IM-26985-159 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000329167|ensembl:ENST00000382888|ensembl:ENSP00000372344|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENST00000398261|ensembl:ENSP00000381311|ensembl:ENST00000420906|ensembl:ENSP00000399251|ensembl:ENST00000503128|ensembl:ENSP00000425761|ensembl:ENSP00000423972|ensembl:ENST00000514045|ensembl:ENSP00000421681|ensembl:ENST00000678714|ensembl:ENSP00000504221|ensembl:ENST00000312087|ensembl:ENSP00000308780|ensembl:ENST00000353275|refseq:NP_001035889.1|refseq:NP_015627.1|refseq:NP_579877.1|refseq:XP_011511859.1|refseq:XP_011511862.1|refseq:NP_579878.1|refseq:NP_579889.1|refseq:NP_579890.1|refseq:XP_005248058.1|refseq:XP_005248062.1|ensembl:ENSG00000109685(gene)|ensembl:ENST00000382891(transcript)|ensembl:ENST00000382892(transcript)|ensembl:ENST00000382895(transcript)|ensembl:ENST00000508803(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003289"(atrial septum primum morphogenesis)|go:"GO:0003290"(atrial septum secundum morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0060348"(bone development)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000313(PWWP)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR006560(AWS)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036910|interpro:IPR041306|mint:O96028|rcsb pdb:5LSU|rcsb pdb:5VC8|rcsb pdb:6UE6|rcsb pdb:6XCG|rcsb pdb:7CRO|rcsb pdb:7LMT|rcsb pdb:7MDN|reactome:R-HSA-3214841|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|refseq:XP_006713977.1|refseq:XP_016864076.1|refseq:XP_016864077.1|dip:DIP-57224N ensembl:ENST00000259396(transcript)|go:"GO:0002682"(regulation of immune system process)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006953"(acute-phase response)|go:"GO:0006954"(inflammatory response)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0032715"(negative regulation of interleukin-6 production)|go:"GO:0032720"(negative regulation of tumor necrosis factor production)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032732"(positive regulation of interleukin-1 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035580"(specific granule lumen)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR001500(Alpha-1-acid glycoprotein)|interpro:IPR012674(Calycin)|mint:P02763|rcsb pdb:3KQ0|reactome:R-HSA-114608|reactome:R-HSA-6798695|ensembl:ENSG00000229314(gene)|refseq:NP_000598.2 - - comment:"author score: 31" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:uqzt7OSAe3MVGdh7z33m/zM/w4w9606 rogid:LHDJJ6oC7gUXo8CC7Xn6EUeA8Gk9606 rigid:0Ma0qTPLbtz9RotEjP18QWARgs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O96028 uniprotkb:P02787 intact:EBI-2693298|uniprotkb:A2A2T3|uniprotkb:A2A2T4|uniprotkb:A7MCZ1|uniprotkb:O96031|uniprotkb:Q4VBY8|uniprotkb:Q672J1|uniprotkb:Q6IS00|uniprotkb:Q86V01|uniprotkb:Q9BZB4|uniprotkb:Q9UI92|uniprotkb:Q9UPR2|intact:EBI-3438110|uniprotkb:D3DVQ2|uniprotkb:A2A2T2|intact:EBI-28971215|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENSP00000423972 intact:EBI-714319|uniprotkb:O43890|uniprotkb:Q9NQB8|uniprotkb:Q9UHV0|uniprotkb:Q1HBA5|ensembl:ENSP00000385834 psi-mi:nsd2_human(display_long)|uniprotkb:NSD2(gene name)|psi-mi:NSD2(display_short)|uniprotkb:KIAA1090(gene name synonym)|uniprotkb:MMSET(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Protein trithorax-5(gene name synonym)|uniprotkb:TRX5(gene name synonym)|uniprotkb:WHSC1(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein(gene name synonym) psi-mi:trfe_human(display_long)|uniprotkb:Siderophilin(gene name synonym)|uniprotkb:Beta-1 metal-binding globulin(gene name synonym)|uniprotkb:TF(gene name)|psi-mi:TF(display_short)|uniprotkb:PRO1400(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486814|imex:IM-26985-159 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000329167|ensembl:ENST00000382888|ensembl:ENSP00000372344|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENST00000398261|ensembl:ENSP00000381311|ensembl:ENST00000420906|ensembl:ENSP00000399251|ensembl:ENST00000503128|ensembl:ENSP00000425761|ensembl:ENSP00000423972|ensembl:ENST00000514045|ensembl:ENSP00000421681|ensembl:ENST00000678714|ensembl:ENSP00000504221|ensembl:ENST00000312087|ensembl:ENSP00000308780|ensembl:ENST00000353275|refseq:NP_001035889.1|refseq:NP_015627.1|refseq:NP_579877.1|refseq:XP_011511859.1|refseq:XP_011511862.1|refseq:NP_579878.1|refseq:NP_579889.1|refseq:NP_579890.1|refseq:XP_005248058.1|refseq:XP_005248062.1|ensembl:ENSG00000109685(gene)|ensembl:ENST00000382891(transcript)|ensembl:ENST00000382892(transcript)|ensembl:ENST00000382895(transcript)|ensembl:ENST00000508803(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003289"(atrial septum primum morphogenesis)|go:"GO:0003290"(atrial septum secundum morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0060348"(bone development)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000313(PWWP)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR006560(AWS)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036910|interpro:IPR041306|mint:O96028|rcsb pdb:5LSU|rcsb pdb:5VC8|rcsb pdb:6UE6|rcsb pdb:6XCG|rcsb pdb:7CRO|rcsb pdb:7LMT|rcsb pdb:7MDN|reactome:R-HSA-3214841|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|refseq:XP_006713977.1|refseq:XP_016864076.1|refseq:XP_016864077.1|dip:DIP-57224N refseq:NP_001054.1|rcsb pdb:1JQF|rcsb pdb:1N7W|rcsb pdb:1N7X|rcsb pdb:1N84|rcsb pdb:1OQG|rcsb pdb:1OQH|rcsb pdb:1RYO|rcsb pdb:1SUV|rcsb pdb:2HAU|rcsb pdb:2HAV|rcsb pdb:2O7U|rcsb pdb:2O84|rcsb pdb:3FGS|rcsb pdb:3QYT|rcsb pdb:3S9L|rcsb pdb:3S9M|rcsb pdb:1FQF|rcsb pdb:3S9N|rcsb pdb:3SKP|rcsb pdb:3V83|rcsb pdb:3V89|rcsb pdb:3V8X|rcsb pdb:4H0W|rcsb pdb:4X1B|rcsb pdb:4X1D|rcsb pdb:5DYH|rcsb pdb:5H52|rcsb pdb:5WTD|rcsb pdb:5X5P|rcsb pdb:5Y6K|rcsb pdb:6CTC|rcsb pdb:6D03|rcsb pdb:6D04|rcsb pdb:6D05|rcsb pdb:3VE1|rcsb pdb:6JAS|rcsb pdb:6SOY|rcsb pdb:6SOZ|rcsb pdb:6UJ6|reactome:R-HSA-114608|reactome:R-HSA-381426|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8957275|reactome:R-HSA-917937|reactome:R-HSA-917977|go:"GO:0034986"(iron chaperone activity)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0045178"(basal part of cell)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0060395"(SMAD protein signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0071281"(cellular response to iron ion)|go:"GO:0072562"(blood microparticle)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990712"(HFE-transferrin receptor complex)|go:"GO:2000147"(positive regulation of cell motility)|interpro:IPR001156(Peptidase S60, transferrin lactoferrin)|interpro:IPR016357(Transferrin)|interpro:IPR018195|interpro:IPR030685|mint:P02787|rcsb pdb:1A8E|go:"GO:0034774"(secretory granule lumen)|rcsb pdb:1A8F|rcsb pdb:1B3E|rcsb pdb:1BP5|rcsb pdb:1BTJ|rcsb pdb:1D3K|rcsb pdb:1D4N|rcsb pdb:1DTG|rcsb pdb:1FQE|ensembl:ENSG00000091513(gene)|ensembl:ENST00000402696(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007015"(actin filament organization)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008199"(ferric iron binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031982"(vesicle)|go:"GO:0034756"(regulation of iron ion transport)|refseq:XP_016862578.1|refseq:XP_016862579.1|dip:DIP-2738N - - comment:"author score: 31" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:uqzt7OSAe3MVGdh7z33m/zM/w4w9606 rogid:CN9nME9TVV6/FGrhH6XHtJF9/HI9606 rigid:0Ma0qTPLbtz9RotEjP18QWARgs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O96028 uniprotkb:P02790 intact:EBI-2693298|uniprotkb:A2A2T3|uniprotkb:A2A2T4|uniprotkb:A7MCZ1|uniprotkb:O96031|uniprotkb:Q4VBY8|uniprotkb:Q672J1|uniprotkb:Q6IS00|uniprotkb:Q86V01|uniprotkb:Q9BZB4|uniprotkb:Q9UI92|uniprotkb:Q9UPR2|intact:EBI-3438110|uniprotkb:D3DVQ2|uniprotkb:A2A2T2|intact:EBI-28971215|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENSP00000423972 intact:EBI-1223791|uniprotkb:B2R957|ensembl:ENSP00000265983 psi-mi:nsd2_human(display_long)|uniprotkb:NSD2(gene name)|psi-mi:NSD2(display_short)|uniprotkb:KIAA1090(gene name synonym)|uniprotkb:MMSET(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Protein trithorax-5(gene name synonym)|uniprotkb:TRX5(gene name synonym)|uniprotkb:WHSC1(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein(gene name synonym) psi-mi:hemo_human(display_long)|uniprotkb:HPX(gene name)|psi-mi:HPX(display_short)|uniprotkb:Beta-1B-glycoprotein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486814|imex:IM-26985-159 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000329167|ensembl:ENST00000382888|ensembl:ENSP00000372344|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENST00000398261|ensembl:ENSP00000381311|ensembl:ENST00000420906|ensembl:ENSP00000399251|ensembl:ENST00000503128|ensembl:ENSP00000425761|ensembl:ENSP00000423972|ensembl:ENST00000514045|ensembl:ENSP00000421681|ensembl:ENST00000678714|ensembl:ENSP00000504221|ensembl:ENST00000312087|ensembl:ENSP00000308780|ensembl:ENST00000353275|refseq:NP_001035889.1|refseq:NP_015627.1|refseq:NP_579877.1|refseq:XP_011511859.1|refseq:XP_011511862.1|refseq:NP_579878.1|refseq:NP_579889.1|refseq:NP_579890.1|refseq:XP_005248058.1|refseq:XP_005248062.1|ensembl:ENSG00000109685(gene)|ensembl:ENST00000382891(transcript)|ensembl:ENST00000382892(transcript)|ensembl:ENST00000382895(transcript)|ensembl:ENST00000508803(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003289"(atrial septum primum morphogenesis)|go:"GO:0003290"(atrial septum secundum morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0060348"(bone development)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000313(PWWP)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR006560(AWS)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036910|interpro:IPR041306|mint:O96028|rcsb pdb:5LSU|rcsb pdb:5VC8|rcsb pdb:6UE6|rcsb pdb:6XCG|rcsb pdb:7CRO|rcsb pdb:7LMT|rcsb pdb:7MDN|reactome:R-HSA-3214841|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|refseq:XP_006713977.1|refseq:XP_016864076.1|refseq:XP_016864077.1|dip:DIP-57224N refseq:NP_000604.1|dip:DIP-38339N|ensembl:ENSG00000110169(gene)|ensembl:ENST00000265983(transcript)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0002925"(positive regulation of humoral immune response mediated by circulating immunoglobulin)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0015232"(heme transmembrane transporter activity)|go:"GO:0015886"(heme transport)|go:"GO:0020027"(hemoglobin metabolic process)|go:"GO:0042168"(heme metabolic process)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0046872"(metal ion binding)|go:"GO:0060335"(positive regulation of interferon-gamma-mediated signaling pathway)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0072562"(blood microparticle)|interpro:IPR000585(Hemopexin)|interpro:IPR016358(Hemopexin, chordata)|interpro:IPR018486|interpro:IPR018487|interpro:IPR036375|mint:P02790|reactome:R-HSA-2168880 - - comment:"author score: 31" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:uqzt7OSAe3MVGdh7z33m/zM/w4w9606 rogid:ee7ibGnypa0mhzKxQrBukKnrt+Y9606 rigid:0Ma0qTPLbtz9RotEjP18QWARgs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O96028 uniprotkb:P00738 intact:EBI-2693298|uniprotkb:A2A2T3|uniprotkb:A2A2T4|uniprotkb:A7MCZ1|uniprotkb:O96031|uniprotkb:Q4VBY8|uniprotkb:Q672J1|uniprotkb:Q6IS00|uniprotkb:Q86V01|uniprotkb:Q9BZB4|uniprotkb:Q9UI92|uniprotkb:Q9UPR2|intact:EBI-3438110|uniprotkb:D3DVQ2|uniprotkb:A2A2T2|intact:EBI-28971215|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENSP00000423972 intact:EBI-1220767|uniprotkb:P00737|uniprotkb:Q0VAC4|uniprotkb:Q2PP15|uniprotkb:Q3B7J0|uniprotkb:Q6LBY9|uniprotkb:B0AZL5|uniprotkb:Q9UC67|uniprotkb:Q0VAC5|ensembl:ENSP00000348170 psi-mi:nsd2_human(display_long)|uniprotkb:NSD2(gene name)|psi-mi:NSD2(display_short)|uniprotkb:KIAA1090(gene name synonym)|uniprotkb:MMSET(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Protein trithorax-5(gene name synonym)|uniprotkb:TRX5(gene name synonym)|uniprotkb:WHSC1(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein(gene name synonym) psi-mi:hpt_human(display_long)|uniprotkb:HP(gene name)|psi-mi:HP(display_short)|uniprotkb:Zonulin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486814|imex:IM-26985-159 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000329167|ensembl:ENST00000382888|ensembl:ENSP00000372344|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENST00000398261|ensembl:ENSP00000381311|ensembl:ENST00000420906|ensembl:ENSP00000399251|ensembl:ENST00000503128|ensembl:ENSP00000425761|ensembl:ENSP00000423972|ensembl:ENST00000514045|ensembl:ENSP00000421681|ensembl:ENST00000678714|ensembl:ENSP00000504221|ensembl:ENST00000312087|ensembl:ENSP00000308780|ensembl:ENST00000353275|refseq:NP_001035889.1|refseq:NP_015627.1|refseq:NP_579877.1|refseq:XP_011511859.1|refseq:XP_011511862.1|refseq:NP_579878.1|refseq:NP_579889.1|refseq:NP_579890.1|refseq:XP_005248058.1|refseq:XP_005248062.1|ensembl:ENSG00000109685(gene)|ensembl:ENST00000382891(transcript)|ensembl:ENST00000382892(transcript)|ensembl:ENST00000382895(transcript)|ensembl:ENST00000508803(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003289"(atrial septum primum morphogenesis)|go:"GO:0003290"(atrial septum secundum morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0060348"(bone development)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000313(PWWP)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR006560(AWS)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036910|interpro:IPR041306|mint:O96028|rcsb pdb:5LSU|rcsb pdb:5VC8|rcsb pdb:6UE6|rcsb pdb:6XCG|rcsb pdb:7CRO|rcsb pdb:7LMT|rcsb pdb:7MDN|reactome:R-HSA-3214841|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|refseq:XP_006713977.1|refseq:XP_016864076.1|refseq:XP_016864077.1|dip:DIP-57224N refseq:NP_001119574.1|refseq:NP_005134.1|refseq:NP_001305067.1|ensembl:ENSG00000257017(gene)|ensembl:ENST00000355906(transcript)|go:"GO:0002526"(acute inflammatory response)|go:"GO:0004252"(serine-type endopeptidase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006952"(defense response)|go:"GO:0006953"(acute-phase response)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016209"(antioxidant activity)|go:"GO:0030492"(hemoglobin binding)|go:"GO:0031638"(zymogen activation)|go:"GO:0031838"(haptoglobin-hemoglobin complex)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0051354"(negative regulation of oxidoreductase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071682"(endocytic vesicle lumen)|interpro:IPR008292(Haptoglobin)|interpro:IPR009003(Peptidase, trypsin-like serine and cysteine)|interpro:IPR035976|interpro:IPR043504|mint:P00738|rcsb pdb:4WJG|rcsb pdb:4X0L|rcsb pdb:5HU6|rcsb pdb:6TB2|reactome:R-HSA-2168880|go:"GO:0072562"(blood microparticle)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:2000296"(negative regulation of hydrogen peroxide catabolic process)|interpro:IPR000436(Sushi/SCR/CCP)|interpro:IPR001254(Peptidase S1 and S6, chymotrypsin/Hap)|interpro:IPR001314(Peptidase S1A, chymotrypsin)|reactome:R-HSA-6798695 - - comment:"author score: 31" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:uqzt7OSAe3MVGdh7z33m/zM/w4w9606 rogid:IsI1hIXfhsW0goXPHsoADxl7V5g9606 rigid:0Ma0qTPLbtz9RotEjP18QWARgs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O96028 uniprotkb:P02647 intact:EBI-2693298|uniprotkb:A2A2T3|uniprotkb:A2A2T4|uniprotkb:A7MCZ1|uniprotkb:O96031|uniprotkb:Q4VBY8|uniprotkb:Q672J1|uniprotkb:Q6IS00|uniprotkb:Q86V01|uniprotkb:Q9BZB4|uniprotkb:Q9UI92|uniprotkb:Q9UPR2|intact:EBI-3438110|uniprotkb:D3DVQ2|uniprotkb:A2A2T2|intact:EBI-28971215|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENSP00000423972 intact:EBI-701692|uniprotkb:Q6LDN9|uniprotkb:Q6Q785|uniprotkb:A8K866|uniprotkb:Q9UCS8|uniprotkb:Q9UCT8|ensembl:ENSP00000236850|ensembl:ENSP00000352471|ensembl:ENSP00000364469|ensembl:ENSP00000364472 psi-mi:nsd2_human(display_long)|uniprotkb:NSD2(gene name)|psi-mi:NSD2(display_short)|uniprotkb:KIAA1090(gene name synonym)|uniprotkb:MMSET(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Protein trithorax-5(gene name synonym)|uniprotkb:TRX5(gene name synonym)|uniprotkb:WHSC1(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein(gene name synonym) psi-mi:apoa1_human(display_long)|uniprotkb:APOA1(gene name)|psi-mi:APOA1(display_short)|uniprotkb:Apolipoprotein A1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486814|imex:IM-26985-159 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000329167|ensembl:ENST00000382888|ensembl:ENSP00000372344|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENST00000398261|ensembl:ENSP00000381311|ensembl:ENST00000420906|ensembl:ENSP00000399251|ensembl:ENST00000503128|ensembl:ENSP00000425761|ensembl:ENSP00000423972|ensembl:ENST00000514045|ensembl:ENSP00000421681|ensembl:ENST00000678714|ensembl:ENSP00000504221|ensembl:ENST00000312087|ensembl:ENSP00000308780|ensembl:ENST00000353275|refseq:NP_001035889.1|refseq:NP_015627.1|refseq:NP_579877.1|refseq:XP_011511859.1|refseq:XP_011511862.1|refseq:NP_579878.1|refseq:NP_579889.1|refseq:NP_579890.1|refseq:XP_005248058.1|refseq:XP_005248062.1|ensembl:ENSG00000109685(gene)|ensembl:ENST00000382891(transcript)|ensembl:ENST00000382892(transcript)|ensembl:ENST00000382895(transcript)|ensembl:ENST00000508803(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003289"(atrial septum primum morphogenesis)|go:"GO:0003290"(atrial septum secundum morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0060348"(bone development)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000313(PWWP)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR006560(AWS)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036910|interpro:IPR041306|mint:O96028|rcsb pdb:5LSU|rcsb pdb:5VC8|rcsb pdb:6UE6|rcsb pdb:6XCG|rcsb pdb:7CRO|rcsb pdb:7LMT|rcsb pdb:7MDN|reactome:R-HSA-3214841|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|refseq:XP_006713977.1|refseq:XP_016864076.1|refseq:XP_016864077.1|dip:DIP-57224N refseq:NP_000030.1|refseq:NP_001304946.1|refseq:NP_001304947.1|refseq:NP_001304950.1|dip:DIP-29619N|ensembl:ENSG00000118137(gene)|ensembl:ENST00000236850(transcript)|ensembl:ENST00000359492(transcript)|ensembl:ENST00000375320(transcript)|ensembl:ENST00000375323(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002719"(negative regulation of cytokine production involved in immune response)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006656"(phosphatidylcholine biosynthetic process)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007584"(response to nutrient)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008211"(glucocorticoid metabolic process)|go:"GO:0009986"(cell surface)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0010873"(positive regulation of cholesterol esterification)|go:"GO:0010875"(positive regulation of cholesterol efflux)|go:"GO:0010898"(positive regulation of triglyceride catabolic process)|go:"GO:0010903"(negative regulation of very-low-density lipoprotein particle remodeling)|go:"GO:0014012"(peripheral nervous system axon regeneration)|go:"GO:0015485"(cholesterol binding)|go:"GO:0018158"(protein oxidation)|go:"GO:0018206"(peptidyl-methionine modification)|go:"GO:0019899"(enzyme binding)|go:"GO:0019915"(lipid storage)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030300"(regulation of intestinal cholesterol absorption)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030325"(adrenal gland development)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032489"(regulation of Cdc42 protein signal transduction)|go:"GO:0032691"(negative regulation of interleukin-1 beta production)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0033700"(phospholipid efflux)|go:"GO:0034115"(negative regulation of heterotypic cell-cell adhesion)|go:"GO:0034190"(apolipoprotein receptor binding)|go:"GO:0034191"(apolipoprotein A-I receptor binding)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034363"(intermediate-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034365"(discoidal high-density lipoprotein particle)|go:"GO:0034366"(spherical high-density lipoprotein particle)|go:"GO:0034372"(very-low-density lipoprotein particle remodeling)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034380"(high-density lipoprotein particle assembly)|go:"GO:0034384"(high-density lipoprotein particle clearance)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0042157"(lipoprotein metabolic process)|go:"GO:0042158"(lipoprotein biosynthetic process)|go:"GO:0042493"|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043627"(response to estrogen)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0045499"(chemorepellent activity)|go:"GO:0045723"(positive regulation of fatty acid biosynthetic process)|go:"GO:0046470"(phosphatidylcholine metabolic process)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0050766"(positive regulation of phagocytosis)|go:"GO:0050821"(protein stabilization)|go:"GO:0050919"(negative chemotaxis)|go:"GO:0051006"(positive regulation of lipoprotein lipase activity)|go:"GO:0051180"(vitamin transport)|go:"GO:0051345"(positive regulation of hydrolase activity)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0055091"(phospholipid homeostasis)|go:"GO:0055102"(lipase inhibitor activity)|go:"GO:0060192"(negative regulation of lipase activity)|go:"GO:0060228"(phosphatidylcholine-sterol O-acyltransferase activator activity)|go:"GO:0060354"(negative regulation of cell adhesion molecule production)|go:"GO:0060761"(negative regulation of response to cytokine stimulus)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070508"(cholesterol import)|go:"GO:0070653"(high-density lipoprotein particle receptor binding)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0072562"(blood microparticle)|go:"GO:0120020"(cholesterol transfer activity)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902995"(positive regulation of phospholipid efflux)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000074(Apolipoprotein A1/A4/E)|mint:P02647|rcsb pdb:1AV1|rcsb pdb:1GW3|rcsb pdb:1GW4|rcsb pdb:1ODP|rcsb pdb:1ODQ|rcsb pdb:1ODR|rcsb pdb:2MSC|rcsb pdb:2MSD|rcsb pdb:2MSE|rcsb pdb:2N5E|rcsb pdb:3K2S|rcsb pdb:3R2P|rcsb pdb:4V6M|rcsb pdb:6CC9|rcsb pdb:6CCH|rcsb pdb:6CCX|rcsb pdb:6CLZ|rcsb pdb:6CM1|rcsb pdb:6PTS|rcsb pdb:6PTW|rcsb pdb:6W4E|rcsb pdb:6W4F|rcsb pdb:7KJR|reactome:R-HSA-114608|reactome:R-HSA-1369062|reactome:R-HSA-1989781|reactome:R-HSA-2168880|reactome:R-HSA-3000471|reactome:R-HSA-3000480|reactome:R-HSA-381426|reactome:R-HSA-5682113|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-8963896|reactome:R-HSA-8963901|reactome:R-HSA-8964011|reactome:R-HSA-8964058|reactome:R-HSA-9707616|reactome:R-HSA-975634|reactome:R-HSA-977225 - - comment:"author score: 34" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:uqzt7OSAe3MVGdh7z33m/zM/w4w9606 rogid:yEzPDeU8Uu/43dkLLOBAy6ey1vs9606 rigid:0Ma0qTPLbtz9RotEjP18QWARgs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O96028 uniprotkb:P68871 intact:EBI-2693298|uniprotkb:A2A2T3|uniprotkb:A2A2T4|uniprotkb:A7MCZ1|uniprotkb:O96031|uniprotkb:Q4VBY8|uniprotkb:Q672J1|uniprotkb:Q6IS00|uniprotkb:Q86V01|uniprotkb:Q9BZB4|uniprotkb:Q9UI92|uniprotkb:Q9UPR2|intact:EBI-3438110|uniprotkb:D3DVQ2|uniprotkb:A2A2T2|intact:EBI-28971215|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENSP00000423972 intact:EBI-715554|ensembl:ENSP00000333994|ensembl:ENSP00000494175|uniprotkb:P02023|uniprotkb:Q13852|uniprotkb:Q14481|uniprotkb:Q14510|uniprotkb:Q45KT0|uniprotkb:Q6FI08|uniprotkb:Q8IZI1|uniprotkb:Q9BX96|uniprotkb:Q9UCP8|uniprotkb:Q9UCP9|uniprotkb:A4GX73|uniprotkb:B2ZUE0|uniprotkb:Q549N7|uniprotkb:Q6R7N2|uniprotkb:Q9UCD6 psi-mi:nsd2_human(display_long)|uniprotkb:NSD2(gene name)|psi-mi:NSD2(display_short)|uniprotkb:KIAA1090(gene name synonym)|uniprotkb:MMSET(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Protein trithorax-5(gene name synonym)|uniprotkb:TRX5(gene name synonym)|uniprotkb:WHSC1(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein(gene name synonym) psi-mi:hbb_human(display_long)|uniprotkb:Hemoglobin beta chain(gene name synonym)|uniprotkb:Beta-globin(gene name synonym)|uniprotkb:HBB(gene name)|psi-mi:HBB(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486814|imex:IM-26985-159 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000329167|ensembl:ENST00000382888|ensembl:ENSP00000372344|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENST00000398261|ensembl:ENSP00000381311|ensembl:ENST00000420906|ensembl:ENSP00000399251|ensembl:ENST00000503128|ensembl:ENSP00000425761|ensembl:ENSP00000423972|ensembl:ENST00000514045|ensembl:ENSP00000421681|ensembl:ENST00000678714|ensembl:ENSP00000504221|ensembl:ENST00000312087|ensembl:ENSP00000308780|ensembl:ENST00000353275|refseq:NP_001035889.1|refseq:NP_015627.1|refseq:NP_579877.1|refseq:XP_011511859.1|refseq:XP_011511862.1|refseq:NP_579878.1|refseq:NP_579889.1|refseq:NP_579890.1|refseq:XP_005248058.1|refseq:XP_005248062.1|ensembl:ENSG00000109685(gene)|ensembl:ENST00000382891(transcript)|ensembl:ENST00000382892(transcript)|ensembl:ENST00000382895(transcript)|ensembl:ENST00000508803(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003289"(atrial septum primum morphogenesis)|go:"GO:0003290"(atrial septum secundum morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0060348"(bone development)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000313(PWWP)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR006560(AWS)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036910|interpro:IPR041306|mint:O96028|rcsb pdb:5LSU|rcsb pdb:5VC8|rcsb pdb:6UE6|rcsb pdb:6XCG|rcsb pdb:7CRO|rcsb pdb:7LMT|rcsb pdb:7MDN|reactome:R-HSA-3214841|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|refseq:XP_006713977.1|refseq:XP_016864076.1|refseq:XP_016864077.1|dip:DIP-57224N ensembl:ENSG00000244734(gene)|ensembl:ENST00000335295(transcript)|ensembl:ENST00000647020(transcript)|refseq:NP_000509.1|rcsb pdb:1XZ4|rcsb pdb:1XZ2|rcsb pdb:1XZ5|rcsb pdb:1XZ7|rcsb pdb:1XZU|rcsb pdb:1XZV|rcsb pdb:1Y09|rcsb pdb:1Y0A|rcsb pdb:1Y0C|rcsb pdb:1Y0D|rcsb pdb:1Y0T|rcsb pdb:1Y0W|rcsb pdb:1Y22|rcsb pdb:1Y2Z|rcsb pdb:1Y31|rcsb pdb:1Y35|rcsb pdb:1Y45|rcsb pdb:1Y46|rcsb pdb:1Y4B|rcsb pdb:1Y4F|rcsb pdb:1Y4G|rcsb pdb:1Y4P|rcsb pdb:1Y4Q|rcsb pdb:1Y4R|rcsb pdb:1Y4V|rcsb pdb:1Y5F|rcsb pdb:1Y5J|rcsb pdb:1Y5K|rcsb pdb:1Y7C|rcsb pdb:1Y7D|rcsb pdb:1Y7G|rcsb pdb:1Y7Z|rcsb pdb:1Y83|rcsb pdb:1Y85|rcsb pdb:1Y8W|rcsb pdb:1YDZ|rcsb pdb:1YE0|rcsb pdb:1YE1|rcsb pdb:1YE2|rcsb pdb:1YEN|rcsb pdb:1YEO|rcsb pdb:1YEQ|rcsb pdb:1YEU|rcsb pdb:1YEV|rcsb pdb:1YFF|rcsb pdb:1YG5|rcsb pdb:1YGD|rcsb pdb:1YGF|rcsb pdb:1YH9|rcsb pdb:1YHE|rcsb pdb:1YHR|rcsb pdb:1YIE|rcsb pdb:1YIH|rcsb pdb:1YVQ|rcsb pdb:1YZI|rcsb pdb:2D5Z|rcsb pdb:2D60|rcsb pdb:2DN1|rcsb pdb:2DN2|rcsb pdb:2DN3|rcsb pdb:2DXM|rcsb pdb:1YVT|rcsb pdb:2H35|rcsb pdb:2HBC|rcsb pdb:2HBD|rcsb pdb:2HBE|rcsb pdb:2HBF|rcsb pdb:2HBS|rcsb pdb:2HCO|rcsb pdb:2HHB|rcsb pdb:2HHD|rcsb pdb:2HHE|rcsb pdb:2M6Z|rcsb pdb:2W6V|rcsb pdb:2W72|rcsb pdb:2YRS|rcsb pdb:3B75|rcsb pdb:3D17|rcsb pdb:3D7O|rcsb pdb:3DUT|rcsb pdb:3HHB|rcsb pdb:3IC0|rcsb pdb:3IC2|rcsb pdb:3HXN|rcsb pdb:3KMF|rcsb pdb:3NL7|rcsb pdb:3NMM|rcsb pdb:3ODQ|rcsb pdb:3ONZ|rcsb pdb:3OO4|rcsb pdb:3OO5|rcsb pdb:3P5Q|rcsb pdb:3QJB|rcsb pdb:3QJC|rcsb pdb:3QJD|rcsb pdb:3QJE|rcsb pdb:3R5I|rcsb pdb:3S65|rcsb pdb:3S66|rcsb pdb:3SZK|go:"GO:0005344"(oxygen carrier activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0005833"(hemoglobin complex)|go:"GO:0008217"(regulation of blood pressure)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0015671"(oxygen transport)|go:"GO:0019825"(oxygen binding)|go:"GO:0020037"(heme binding)|go:"GO:0030185"(nitric oxide transport)|go:"GO:0030492"(hemoglobin binding)|go:"GO:0031721"(hemoglobin alpha binding)|go:"GO:0031838"(haptoglobin-hemoglobin complex)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0043177"(organic acid binding)|go:"GO:0045429"(positive regulation of nitric oxide biosynthetic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070293"(renal absorption)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0098869"(cellular oxidant detoxification)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000971(Globin, subset)|interpro:IPR002337(Haemoglobin, beta)|interpro:IPR009050(Globin-like)|interpro:IPR012292(Globin)|mint:P68871|rcsb pdb:1A00|rcsb pdb:1A01|rcsb pdb:1A0U|rcsb pdb:1A0Z|rcsb pdb:1A3N|go:"GO:0072562"(blood microparticle)|rcsb pdb:1A3O|rcsb pdb:1ABW|rcsb pdb:1ABY|rcsb pdb:1AJ9|rcsb pdb:1B86|rcsb pdb:1BAB|rcsb pdb:1BBB|rcsb pdb:1BIJ|rcsb pdb:1BUW|rcsb pdb:1BZ0|rcsb pdb:1BZ1|rcsb pdb:1BZZ|rcsb pdb:1C7B|rcsb pdb:1C7C|rcsb pdb:1C7D|rcsb pdb:1CBL|rcsb pdb:1CBM|rcsb pdb:1CH4|rcsb pdb:1CLS|rcsb pdb:1CMY|rcsb pdb:1COH|rcsb pdb:1DKE|rcsb pdb:1DXT|rcsb pdb:1DXU|rcsb pdb:1DXV|rcsb pdb:1FN3|rcsb pdb:1G9V|rcsb pdb:1GBU|rcsb pdb:1GBV|rcsb pdb:1GLI|rcsb pdb:1GZX|rcsb pdb:1HAB|rcsb pdb:1HAC|rcsb pdb:1HBA|rcsb pdb:1HBB|rcsb pdb:1HBS|rcsb pdb:1HCO|rcsb pdb:1HDB|rcsb pdb:1HGA|rcsb pdb:1HGB|rcsb pdb:1HGC|rcsb pdb:1HHO|rcsb pdb:1IRD|rcsb pdb:1J3Y|rcsb pdb:1J40|rcsb pdb:1J41|rcsb pdb:1J7S|rcsb pdb:1J7W|rcsb pdb:1J7Y|rcsb pdb:1JY7|rcsb pdb:1J3Z|rcsb pdb:1K0Y|rcsb pdb:1K1K|rcsb pdb:1KD2|rcsb pdb:1LFL|rcsb pdb:1LFQ|rcsb pdb:1LFT|rcsb pdb:1LFV|rcsb pdb:1LFY|rcsb pdb:1LFZ|rcsb pdb:1LJW|rcsb pdb:1M9P|rcsb pdb:1MKO|rcsb pdb:1NEJ|rcsb pdb:1NIH|rcsb pdb:1NQP|rcsb pdb:1O1I|rcsb pdb:1O1J|rcsb pdb:1O1K|rcsb pdb:1O1L|rcsb pdb:1O1M|rcsb pdb:1O1N|rcsb pdb:1O1O|rcsb pdb:1O1P|rcsb pdb:1QI8|rcsb pdb:1QSH|rcsb pdb:1QSI|rcsb pdb:1QXD|rcsb pdb:1QXE|rcsb pdb:1R1X|rcsb pdb:1R1Y|rcsb pdb:1RPS|rcsb pdb:1RQ3|rcsb pdb:1RQ4|rcsb pdb:1RQA|rcsb pdb:1RVW|rcsb pdb:1SDK|rcsb pdb:1SDL|rcsb pdb:1THB|rcsb pdb:1UIW|rcsb pdb:1VWT|rcsb pdb:1XXT|rcsb pdb:1XY0|rcsb pdb:1XYE|reactome:R-HSA-1237044|reactome:R-HSA-1247673|reactome:R-HSA-2168880|reactome:R-HSA-6798695|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9707564|reactome:R-HSA-9707616|reactome:R-HSA-983231|rcsb pdb:7JY3|rcsb pdb:3WCP|rcsb pdb:3WHM|rcsb pdb:4FC3|rcsb pdb:4HHB|rcsb pdb:4IJ2|rcsb pdb:4L7Y|rcsb pdb:4M4A|rcsb pdb:4M4B|rcsb pdb:4MQC|rcsb pdb:4MQG|rcsb pdb:4MQH|rcsb pdb:4MQI|rcsb pdb:4N7N|rcsb pdb:4N7O|rcsb pdb:4N7P|rcsb pdb:4N8T|rcsb pdb:4NI0|rcsb pdb:3W4U|rcsb pdb:4NI1|rcsb pdb:4ROL|rcsb pdb:4WJG|rcsb pdb:4X0L|rcsb pdb:4XS0|rcsb pdb:5E29|rcsb pdb:5E6E|rcsb pdb:5E83|rcsb pdb:5EE4|rcsb pdb:5HU6|rcsb pdb:5HY8|rcsb pdb:5JDO|rcsb pdb:5KDQ|rcsb pdb:5KSI|rcsb pdb:5KSJ|rcsb pdb:5NI1|rcsb pdb:5SW7|rcsb pdb:5U3I|rcsb pdb:5UCU|rcsb pdb:5UFJ|rcsb pdb:5URC|rcsb pdb:5VMM|rcsb pdb:5WOG|rcsb pdb:5WOH|rcsb pdb:5X2R|rcsb pdb:5X2S|rcsb pdb:5X2T|rcsb pdb:5X2U|rcsb pdb:6BB5|rcsb pdb:6BNR|rcsb pdb:6BWP|rcsb pdb:6BWU|rcsb pdb:6DI4|rcsb pdb:6FQF|rcsb pdb:6HAL|rcsb pdb:4ROM|rcsb pdb:6HBW|rcsb pdb:6HK2|rcsb pdb:6KA9|rcsb pdb:6KAE|rcsb pdb:6KAH|rcsb pdb:6KAI|rcsb pdb:6KAO|rcsb pdb:6KAP|rcsb pdb:6KAQ|rcsb pdb:6KAR|rcsb pdb:6KAS|rcsb pdb:6KAT|rcsb pdb:6KAU|rcsb pdb:6KAV|rcsb pdb:6KYE|rcsb pdb:6L5V|rcsb pdb:6L5W|rcsb pdb:6L5X|rcsb pdb:6L5Y|rcsb pdb:6LCW|rcsb pdb:6LCX|rcsb pdb:6NBC|rcsb pdb:6NBD|rcsb pdb:6NQ5|rcsb pdb:6TB2|rcsb pdb:6XD9|rcsb pdb:6XDT|rcsb pdb:6XE7|rcsb pdb:7AET|rcsb pdb:7AEU|rcsb pdb:7AEV|rcsb pdb:7JJQ|rcsb pdb:7JXZ|rcsb pdb:7JY0|rcsb pdb:7JY1|dip:DIP-35526N - - comment:"author score: 40" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:uqzt7OSAe3MVGdh7z33m/zM/w4w9606 rogid:Y5tl4dXE3PBfaK/0lROD6QJ4U+c9606 rigid:0Ma0qTPLbtz9RotEjP18QWARgs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O96028 uniprotkb:P31025 intact:EBI-2693298|uniprotkb:A2A2T3|uniprotkb:A2A2T4|uniprotkb:A7MCZ1|uniprotkb:O96031|uniprotkb:Q4VBY8|uniprotkb:Q672J1|uniprotkb:Q6IS00|uniprotkb:Q86V01|uniprotkb:Q9BZB4|uniprotkb:Q9UI92|uniprotkb:Q9UPR2|intact:EBI-3438110|uniprotkb:D3DVQ2|uniprotkb:A2A2T2|intact:EBI-28971215|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENSP00000423972 intact:EBI-1052433|uniprotkb:Q5T8A1|ensembl:ENSP00000263598|ensembl:ENSP00000360846 psi-mi:nsd2_human(display_long)|uniprotkb:NSD2(gene name)|psi-mi:NSD2(display_short)|uniprotkb:KIAA1090(gene name synonym)|uniprotkb:MMSET(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Protein trithorax-5(gene name synonym)|uniprotkb:TRX5(gene name synonym)|uniprotkb:WHSC1(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein(gene name synonym) psi-mi:lcn1_human(display_long)|uniprotkb:Tear prealbumin(gene name synonym)|uniprotkb:Tear lipocalin(gene name synonym)|uniprotkb:LCN1(gene name)|psi-mi:LCN1(display_short)|uniprotkb:VEGP(gene name synonym)|uniprotkb:von Ebner gland protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486814|imex:IM-26985-159 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000329167|ensembl:ENST00000382888|ensembl:ENSP00000372344|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENST00000398261|ensembl:ENSP00000381311|ensembl:ENST00000420906|ensembl:ENSP00000399251|ensembl:ENST00000503128|ensembl:ENSP00000425761|ensembl:ENSP00000423972|ensembl:ENST00000514045|ensembl:ENSP00000421681|ensembl:ENST00000678714|ensembl:ENSP00000504221|ensembl:ENST00000312087|ensembl:ENSP00000308780|ensembl:ENST00000353275|refseq:NP_001035889.1|refseq:NP_015627.1|refseq:NP_579877.1|refseq:XP_011511859.1|refseq:XP_011511862.1|refseq:NP_579878.1|refseq:NP_579889.1|refseq:NP_579890.1|refseq:XP_005248058.1|refseq:XP_005248062.1|ensembl:ENSG00000109685(gene)|ensembl:ENST00000382891(transcript)|ensembl:ENST00000382892(transcript)|ensembl:ENST00000382895(transcript)|ensembl:ENST00000508803(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003289"(atrial septum primum morphogenesis)|go:"GO:0003290"(atrial septum secundum morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0060348"(bone development)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000313(PWWP)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR006560(AWS)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036910|interpro:IPR041306|mint:O96028|rcsb pdb:5LSU|rcsb pdb:5VC8|rcsb pdb:6UE6|rcsb pdb:6XCG|rcsb pdb:7CRO|rcsb pdb:7LMT|rcsb pdb:7MDN|reactome:R-HSA-3214841|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|refseq:XP_006713977.1|refseq:XP_016864076.1|refseq:XP_016864077.1|dip:DIP-57224N refseq:NP_002288.1|refseq:NP_001239547.1|refseq:NP_001239548.1|refseq:NP_001239546.1|ensembl:ENSG00000160349(gene)|ensembl:ENST00000263598(transcript)|ensembl:ENST00000371781(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0004869"(cysteine-type endopeptidase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006508"(proteolysis)|go:"GO:0008270"(zinc ion binding)|go:"GO:0031404"(chloride ion binding)|go:"GO:0036094"(small molecule binding)|go:"GO:0050896"(response to stimulus)|go:"GO:0050909"(sensory perception of taste)|interpro:IPR000566(Lipocalin-related protein and Bos/Can/Equ allergen)|interpro:IPR002345(Lipocalin)|interpro:IPR002450(von Ebner's gland protein/ Bos/Can allergen)|interpro:IPR012674(Calycin)|mint:P31025|rcsb pdb:1XKI|rcsb pdb:3EYC|rcsb pdb:4QAF|rcsb pdb:5T43|reactome:R-HSA-804914 - - comment:"author score: 40" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:uqzt7OSAe3MVGdh7z33m/zM/w4w9606 rogid:bpcDgVZMNuh6M1hEl3b8IncbuO49606 rigid:0Ma0qTPLbtz9RotEjP18QWARgs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O96028 uniprotkb:P02808 intact:EBI-2693298|uniprotkb:A2A2T3|uniprotkb:A2A2T4|uniprotkb:A7MCZ1|uniprotkb:O96031|uniprotkb:Q4VBY8|uniprotkb:Q672J1|uniprotkb:Q6IS00|uniprotkb:Q86V01|uniprotkb:Q9BZB4|uniprotkb:Q9UI92|uniprotkb:Q9UPR2|intact:EBI-3438110|uniprotkb:D3DVQ2|uniprotkb:A2A2T2|intact:EBI-28971215|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENSP00000423972 intact:EBI-738687|uniprotkb:B2R4F8|uniprotkb:A6NKE9|ensembl:ENSP00000246895|ensembl:ENSP00000489243|ensembl:ENSP00000503126 psi-mi:nsd2_human(display_long)|uniprotkb:NSD2(gene name)|psi-mi:NSD2(display_short)|uniprotkb:KIAA1090(gene name synonym)|uniprotkb:MMSET(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Protein trithorax-5(gene name synonym)|uniprotkb:TRX5(gene name synonym)|uniprotkb:WHSC1(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein(gene name synonym) psi-mi:stat_human(display_long)|uniprotkb:STATH(gene name)|psi-mi:STATH(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486814|imex:IM-26985-159 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000329167|ensembl:ENST00000382888|ensembl:ENSP00000372344|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENST00000398261|ensembl:ENSP00000381311|ensembl:ENST00000420906|ensembl:ENSP00000399251|ensembl:ENST00000503128|ensembl:ENSP00000425761|ensembl:ENSP00000423972|ensembl:ENST00000514045|ensembl:ENSP00000421681|ensembl:ENST00000678714|ensembl:ENSP00000504221|ensembl:ENST00000312087|ensembl:ENSP00000308780|ensembl:ENST00000353275|refseq:NP_001035889.1|refseq:NP_015627.1|refseq:NP_579877.1|refseq:XP_011511859.1|refseq:XP_011511862.1|refseq:NP_579878.1|refseq:NP_579889.1|refseq:NP_579890.1|refseq:XP_005248058.1|refseq:XP_005248062.1|ensembl:ENSG00000109685(gene)|ensembl:ENST00000382891(transcript)|ensembl:ENST00000382892(transcript)|ensembl:ENST00000382895(transcript)|ensembl:ENST00000508803(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003289"(atrial septum primum morphogenesis)|go:"GO:0003290"(atrial septum secundum morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0060348"(bone development)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000313(PWWP)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR006560(AWS)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036910|interpro:IPR041306|mint:O96028|rcsb pdb:5LSU|rcsb pdb:5VC8|rcsb pdb:6UE6|rcsb pdb:6XCG|rcsb pdb:7CRO|rcsb pdb:7LMT|rcsb pdb:7MDN|reactome:R-HSA-3214841|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|refseq:XP_006713977.1|refseq:XP_016864076.1|refseq:XP_016864077.1|dip:DIP-57224N refseq:NP_001009181.1|refseq:NP_003145.1|ensembl:ENSG00000126549(gene)|ensembl:ENSG00000282891(gene)|ensembl:ENST00000246895(transcript)|ensembl:ENST00000635686(transcript)|ensembl:ENST00000676772(transcript)|go:"GO:0001503"(ossification)|go:"GO:0005576"(extracellular region)|go:"GO:0030197"(extracellular matrix constituent, lubricant activity)|go:"GO:0030345"(structural constituent of tooth enamel)|go:"GO:0030502"(negative regulation of bone mineralization)|go:"GO:0031214"(biomineral tissue development)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0046541"(saliva secretion)|go:"GO:0046848"(hydroxyapatite binding)|interpro:IPR005575(Statherin)|interpro:IPR030773|mint:P02808 - - comment:"author score: 47" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:uqzt7OSAe3MVGdh7z33m/zM/w4w9606 rogid:Z6n5l57rajALqXtu03bXPtVkzpo9606 rigid:0Ma0qTPLbtz9RotEjP18QWARgs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O96028 uniprotkb:P01009 intact:EBI-2693298|uniprotkb:A2A2T3|uniprotkb:A2A2T4|uniprotkb:A7MCZ1|uniprotkb:O96031|uniprotkb:Q4VBY8|uniprotkb:Q672J1|uniprotkb:Q6IS00|uniprotkb:Q86V01|uniprotkb:Q9BZB4|uniprotkb:Q9UI92|uniprotkb:Q9UPR2|intact:EBI-3438110|uniprotkb:D3DVQ2|uniprotkb:A2A2T2|intact:EBI-28971215|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENSP00000423972 intact:EBI-986224|uniprotkb:Q7M4R2|uniprotkb:Q86U18|uniprotkb:Q86U19|uniprotkb:Q96BF9|uniprotkb:Q96ES1|uniprotkb:Q9P1P0|uniprotkb:A6PX14|uniprotkb:Q0PVP5|uniprotkb:Q13672|uniprotkb:Q53XB8|uniprotkb:Q5U0M1|uniprotkb:B2RDQ8|uniprotkb:Q9UCE6|uniprotkb:Q9UCM3|ensembl:ENSP00000348068|ensembl:ENSP00000376802|ensembl:ENSP00000376803|ensembl:ENSP00000385960|ensembl:ENSP00000390299|ensembl:ENSP00000408474|ensembl:ENSP00000416066|ensembl:ENSP00000416354|ensembl:ENSP00000490054 psi-mi:nsd2_human(display_long)|uniprotkb:NSD2(gene name)|psi-mi:NSD2(display_short)|uniprotkb:KIAA1090(gene name synonym)|uniprotkb:MMSET(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Protein trithorax-5(gene name synonym)|uniprotkb:TRX5(gene name synonym)|uniprotkb:WHSC1(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein(gene name synonym) psi-mi:a1at_human(display_long)|uniprotkb:Alpha-1 protease inhibitor(gene name synonym)|uniprotkb:Alpha-1-antiproteinase(gene name synonym)|uniprotkb:AAT(gene name synonym)|uniprotkb:PI(gene name synonym)|uniprotkb:PRO0684(orf name)|uniprotkb:PRO2209(orf name)|uniprotkb:SERPINA1(gene name)|psi-mi:SERPINA1(display_short)|uniprotkb:Serpin A1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486814|imex:IM-26985-159 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000329167|ensembl:ENST00000382888|ensembl:ENSP00000372344|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENST00000398261|ensembl:ENSP00000381311|ensembl:ENST00000420906|ensembl:ENSP00000399251|ensembl:ENST00000503128|ensembl:ENSP00000425761|ensembl:ENSP00000423972|ensembl:ENST00000514045|ensembl:ENSP00000421681|ensembl:ENST00000678714|ensembl:ENSP00000504221|ensembl:ENST00000312087|ensembl:ENSP00000308780|ensembl:ENST00000353275|refseq:NP_001035889.1|refseq:NP_015627.1|refseq:NP_579877.1|refseq:XP_011511859.1|refseq:XP_011511862.1|refseq:NP_579878.1|refseq:NP_579889.1|refseq:NP_579890.1|refseq:XP_005248058.1|refseq:XP_005248062.1|ensembl:ENSG00000109685(gene)|ensembl:ENST00000382891(transcript)|ensembl:ENST00000382892(transcript)|ensembl:ENST00000382895(transcript)|ensembl:ENST00000508803(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003289"(atrial septum primum morphogenesis)|go:"GO:0003290"(atrial septum secundum morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0060348"(bone development)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000313(PWWP)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR006560(AWS)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036910|interpro:IPR041306|mint:O96028|rcsb pdb:5LSU|rcsb pdb:5VC8|rcsb pdb:6UE6|rcsb pdb:6XCG|rcsb pdb:7CRO|rcsb pdb:7LMT|rcsb pdb:7MDN|reactome:R-HSA-3214841|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|refseq:XP_006713977.1|refseq:XP_016864076.1|refseq:XP_016864077.1|dip:DIP-57224N refseq:NP_000286.3|refseq:NP_001002235.1|refseq:NP_001002236.1|refseq:NP_001121172.1|refseq:NP_001121173.1|refseq:NP_001121174.1|refseq:NP_001121175.1|refseq:NP_001121176.1|refseq:NP_001121177.1|refseq:NP_001121178.1|refseq:NP_001121179.1|refseq:XP_016876859.1|dip:DIP-35493N|ensembl:ENSG00000197249(gene)|ensembl:ENST00000355814(transcript)|ensembl:ENST00000393087(transcript)|ensembl:ENST00000393088(transcript)|ensembl:ENST00000404814(transcript)|ensembl:ENST00000437397(transcript)|ensembl:ENST00000440909(transcript)|ensembl:ENST00000448921(transcript)|ensembl:ENST00000449399(transcript)|ensembl:ENST00000636712(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006953"(acute-phase response)|go:"GO:0007596"(blood coagulation)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|mint:P01009|rcsb pdb:1ATU|rcsb pdb:1EZX|rcsb pdb:1HP7|rcsb pdb:1D5S|rcsb pdb:1IZ2|rcsb pdb:1KCT|rcsb pdb:1OO8|rcsb pdb:1OPH|rcsb pdb:1PSI|rcsb pdb:1QLP|rcsb pdb:1QMB|rcsb pdb:2D26|rcsb pdb:2QUG|rcsb pdb:3CWL|rcsb pdb:3CWM|rcsb pdb:3DRM|rcsb pdb:3DRU|rcsb pdb:3NDD|rcsb pdb:3NDF|rcsb pdb:3NE4|rcsb pdb:3T1P|rcsb pdb:4PYW|rcsb pdb:5IO1|rcsb pdb:5NBU|rcsb pdb:5NBV|rcsb pdb:6HX4|rcsb pdb:6I4V|rcsb pdb:6I7U|rcsb pdb:6IAY|rcsb pdb:6ROD|rcsb pdb:7AEL|rcsb pdb:7API|rcsb pdb:7NPK|rcsb pdb:7NPL|rcsb pdb:8API|rcsb pdb:9API|reactome:R-HSA-114608|reactome:R-HSA-204005|reactome:R-HSA-381426|reactome:R-HSA-5694530|reactome:R-HSA-6798695|reactome:R-HSA-8957275 - - comment:"author score: 48" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:uqzt7OSAe3MVGdh7z33m/zM/w4w9606 rogid:eIbjQWRWsWv+B28IcSUIKJ+Eros9606 rigid:0Ma0qTPLbtz9RotEjP18QWARgs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:O96028 uniprotkb:Q16378 intact:EBI-2693298|uniprotkb:A2A2T3|uniprotkb:A2A2T4|uniprotkb:A7MCZ1|uniprotkb:O96031|uniprotkb:Q4VBY8|uniprotkb:Q672J1|uniprotkb:Q6IS00|uniprotkb:Q86V01|uniprotkb:Q9BZB4|uniprotkb:Q9UI92|uniprotkb:Q9UPR2|intact:EBI-3438110|uniprotkb:D3DVQ2|uniprotkb:A2A2T2|intact:EBI-28971215|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENSP00000423972 intact:EBI-738624|uniprotkb:Q8NFB3|uniprotkb:A8KA69|uniprotkb:F5H0D7|ensembl:ENSP00000228811|ensembl:ENSP00000459468|ensembl:ENSP00000477689 psi-mi:nsd2_human(display_long)|uniprotkb:NSD2(gene name)|psi-mi:NSD2(display_short)|uniprotkb:KIAA1090(gene name synonym)|uniprotkb:MMSET(gene name synonym)|uniprotkb:Multiple myeloma SET domain-containing protein(gene name synonym)|uniprotkb:Nuclear SET domain-containing protein 2(gene name synonym)|uniprotkb:Protein trithorax-5(gene name synonym)|uniprotkb:TRX5(gene name synonym)|uniprotkb:WHSC1(gene name synonym)|uniprotkb:Wolf-Hirschhorn syndrome candidate 1 protein(gene name synonym) psi-mi:prol4_human(display_long)|uniprotkb:PRR4(gene name)|psi-mi:PRR4(display_short)|uniprotkb:LPRP(gene name synonym)|uniprotkb:PROL4(gene name synonym)|uniprotkb:Lacrimal proline-rich protein(gene name synonym)|uniprotkb:Nasopharyngeal carcinoma-associated proline-rich protein 4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486814|imex:IM-26985-159 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000329167|ensembl:ENST00000382888|ensembl:ENSP00000372344|ensembl:ENSP00000372347|ensembl:ENSP00000372348|ensembl:ENSP00000372351|ensembl:ENST00000398261|ensembl:ENSP00000381311|ensembl:ENST00000420906|ensembl:ENSP00000399251|ensembl:ENST00000503128|ensembl:ENSP00000425761|ensembl:ENSP00000423972|ensembl:ENST00000514045|ensembl:ENSP00000421681|ensembl:ENST00000678714|ensembl:ENSP00000504221|ensembl:ENST00000312087|ensembl:ENSP00000308780|ensembl:ENST00000353275|refseq:NP_001035889.1|refseq:NP_015627.1|refseq:NP_579877.1|refseq:XP_011511859.1|refseq:XP_011511862.1|refseq:NP_579878.1|refseq:NP_579889.1|refseq:NP_579890.1|refseq:XP_005248058.1|refseq:XP_005248062.1|ensembl:ENSG00000109685(gene)|ensembl:ENST00000382891(transcript)|ensembl:ENST00000382892(transcript)|ensembl:ENST00000382895(transcript)|ensembl:ENST00000508803(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0003149"(membranous septum morphogenesis)|go:"GO:0003289"(atrial septum primum morphogenesis)|go:"GO:0003290"(atrial septum secundum morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0042799"("histone methyltransferase activity (H4-K20 specific)")|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0046975"("histone methyltransferase activity (H3-K36 specific)")|go:"GO:0048298"(positive regulation of isotype switching to IgA isotypes)|go:"GO:0060348"(bone development)|go:"GO:0070201"(regulation of establishment of protein localization)|go:"GO:2001032"(regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR000313(PWWP)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR006560(AWS)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036910|interpro:IPR041306|mint:O96028|rcsb pdb:5LSU|rcsb pdb:5VC8|rcsb pdb:6UE6|rcsb pdb:6XCG|rcsb pdb:7CRO|rcsb pdb:7LMT|rcsb pdb:7MDN|reactome:R-HSA-3214841|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-69473|refseq:XP_006713977.1|refseq:XP_016864076.1|refseq:XP_016864077.1|dip:DIP-57224N refseq:NP_001092008.2|refseq:NP_009175.2|ensembl:ENSG00000111215(gene)|ensembl:ENSG00000263247(gene)|ensembl:ENSG00000282269(gene)|ensembl:ENST00000228811(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005615"(extracellular space)|go:"GO:0007601"(visual perception)|interpro:IPR026086|mint:Q16378|ensembl:ENST00000574424(transcript)|ensembl:ENST00000614435(transcript) - - comment:"author score: 48" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:uqzt7OSAe3MVGdh7z33m/zM/w4w9606 rogid:wkkslTDK+a/17dqz+iL0yadicwY9606 rigid:0Ma0qTPLbtz9RotEjP18QWARgs0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6UXN9 uniprotkb:Q9UPT8 intact:EBI-1176082|uniprotkb:Q8TEB2|uniprotkb:A8K5R5|intact:EBI-2562464|ensembl:ENSP00000296490 intact:EBI-2562458|uniprotkb:Q9Y420|ensembl:ENSP00000253048 psi-mi:wdr82_human(display_long)|uniprotkb:Protein TMEM113(gene name synonym)|uniprotkb:TMEM113(gene name synonym)|uniprotkb:WDR82(gene name)|psi-mi:WDR82(display_short)|uniprotkb:Swd2(gene name synonym)|uniprotkb:WDR82A(gene name synonym)|uniprotkb:UNQ9342/PRO34047(orf name) psi-mi:zc3h4_human(display_long)|uniprotkb:ZC3H4(gene name)|psi-mi:ZC3H4(display_short)|uniprotkb:C19orf7(gene name synonym)|uniprotkb:KIAA1064(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486793|imex:IM-26985-219 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079498.2|ensembl:ENSG00000164091(gene)|ensembl:ENST00000296490(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005730"(nucleolus)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|interpro:IPR037867|mint:Q6UXN9 refseq:NP_055983.1|ensembl:ENSG00000130749(gene)|ensembl:ENST00000253048(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR036855|interpro:IPR041367|mint:Q9UPT8|rcsb pdb:2CQE|ensembl:ENSP00000253048|refseq:XP_006723176.1 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:0TyKYwpTLd22Cm+ihT1+n0oo12c9606 rogid:TldYBUe8Zf2AZp6Jxkw20jEfMcI9606 rigid:kJVxe3KFuY46057bOZAihX1fa4A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6UXN9 uniprotkb:P62140 intact:EBI-1176082|uniprotkb:Q8TEB2|uniprotkb:A8K5R5|intact:EBI-2562464|ensembl:ENSP00000296490 intact:EBI-352350|uniprotkb:P37140|uniprotkb:Q5U087|uniprotkb:Q6FG45|uniprotkb:D6W565|uniprotkb:B2R5V4|ensembl:ENSP00000296122|ensembl:ENSP00000351298|ensembl:ENSP00000378769 psi-mi:wdr82_human(display_long)|uniprotkb:Protein TMEM113(gene name synonym)|uniprotkb:TMEM113(gene name synonym)|uniprotkb:WDR82(gene name)|psi-mi:WDR82(display_short)|uniprotkb:Swd2(gene name synonym)|uniprotkb:WDR82A(gene name synonym)|uniprotkb:UNQ9342/PRO34047(orf name) psi-mi:pp1b_human(display_long)|uniprotkb:PPP1CB(gene name)|psi-mi:PPP1CB(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486793|imex:IM-26985-219 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079498.2|ensembl:ENSG00000164091(gene)|ensembl:ENST00000296490(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005730"(nucleolus)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|interpro:IPR037867|mint:Q6UXN9 refseq:NP_002700.1|refseq:NP_996759.1|ensembl:ENSG00000213639(gene)|ensembl:ENST00000296122(transcript)|ensembl:ENST00000358506(transcript)|ensembl:ENST00000395366(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0000165"(MAPK cascade)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0016791"(phosphatase activity)|go:"GO:0017018"(myosin phosphatase activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0042587"(glycogen granule)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0046872"(metal ion binding)|go:"GO:0050115"(myosin-light-chain-phosphatase activity)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|mint:P62140|reactome:R-HSA-163560|reactome:R-HSA-2173788|reactome:R-HSA-2565942|reactome:R-HSA-400253|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-5673000|reactome:R-HSA-9660537|dip:DIP-33220N - - comment:"author score: 20" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:0TyKYwpTLd22Cm+ihT1+n0oo12c9606 rogid:VtNJVyimeiEuRDDWtGswTqoSOH89606 rigid:kJVxe3KFuY46057bOZAihX1fa4A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6UXN9 uniprotkb:P62136 intact:EBI-1176082|uniprotkb:Q8TEB2|uniprotkb:A8K5R5|intact:EBI-2562464|ensembl:ENSP00000296490 intact:EBI-357253|uniprotkb:P08129|uniprotkb:P20653|uniprotkb:P22802|uniprotkb:B2R908|intact:EBI-2623163|uniprotkb:Q07161|intact:EBI-2556927|uniprotkb:A6NNR3|ensembl:ENSP00000365936 psi-mi:wdr82_human(display_long)|uniprotkb:Protein TMEM113(gene name synonym)|uniprotkb:TMEM113(gene name synonym)|uniprotkb:WDR82(gene name)|psi-mi:WDR82(display_short)|uniprotkb:Swd2(gene name synonym)|uniprotkb:WDR82A(gene name synonym)|uniprotkb:UNQ9342/PRO34047(orf name) psi-mi:pp1a_human(display_long)|uniprotkb:PPP1CA(gene name)|psi-mi:PPP1CA(display_short)|uniprotkb:PPP1A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486793|imex:IM-26985-219 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079498.2|ensembl:ENSG00000164091(gene)|ensembl:ENST00000296490(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005730"(nucleolus)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|interpro:IPR037867|mint:Q6UXN9 refseq:NP_001008709.1|refseq:NP_002699.1|refseq:NP_996756.1|dip:DIP-221N|dip:DIP-38195N|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035970"(peptidyl-threonine dephosphorylation)|go:"GO:0036496"(regulation of translational initiation by eIF2 alpha dephosphorylation)|go:"GO:0042587"(glycogen granule)|go:"GO:0042752"(regulation of circadian rhythm)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043197"(dendritic spine)|go:"GO:0043204"(perikaryon)|go:"GO:0046872"(metal ion binding)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0051301"(cell division)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106306"|go:"GO:0106307"|go:"GO:1904886"(beta-catenin destruction complex disassembly)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR006186("Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase")|interpro:IPR029052|interpro:IPR031675|interpro:IPR037979|mint:P62136|rcsb pdb:3E7A|rcsb pdb:3E7B|rcsb pdb:3EGG|rcsb pdb:3EGH|rcsb pdb:3HVQ|rcsb pdb:3N5U|rcsb pdb:3V4Y|rcsb pdb:4G9J|rcsb pdb:4MOV|rcsb pdb:4MOY|rcsb pdb:4MP0|rcsb pdb:4XPN|rcsb pdb:5IOH|rcsb pdb:6ALZ|rcsb pdb:6CZO|rcsb pdb:6DCX|rcsb pdb:6DNO|rcsb pdb:6G0I|rcsb pdb:6G0J|rcsb pdb:6GHM|rcsb pdb:6OBN|rcsb pdb:6OBP|rcsb pdb:6OBQ|rcsb pdb:6OBR|rcsb pdb:6OBS|rcsb pdb:6OBU|rcsb pdb:6ZEE|rcsb pdb:6ZEF|rcsb pdb:6ZEG|rcsb pdb:6ZEH|rcsb pdb:6ZEI|rcsb pdb:6ZEJ|rcsb pdb:6ZK6|reactome:R-HSA-163560|reactome:R-HSA-180024|reactome:R-HSA-2173788|reactome:R-HSA-400253|go:"GO:0098793"(presynapse)|ensembl:ENSG00000172531(gene)|ensembl:ENST00000376745(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004722"(protein serine/threonine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0005979"(regulation of glycogen biosynthetic process)|go:"GO:0005981"(regulation of glycogen catabolic process)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0016311"(dephosphorylation)|go:"GO:0016791"(phosphatase activity)|go:"GO:0030324"(lung development) - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:0TyKYwpTLd22Cm+ihT1+n0oo12c9606 rogid:IMypaKng+5AECbCd3N72pgzUlxQ9606 rigid:kJVxe3KFuY46057bOZAihX1fa4A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6UXN9 uniprotkb:O15047 intact:EBI-1176082|uniprotkb:Q8TEB2|uniprotkb:A8K5R5|intact:EBI-2562464|ensembl:ENSP00000296490 intact:EBI-540779|uniprotkb:A6NP62|uniprotkb:Q6PIF3|uniprotkb:Q8TAJ6|intact:EBI-28969638|ensembl:ENSP00000262519|ensembl:ENSP00000507683 psi-mi:wdr82_human(display_long)|uniprotkb:Protein TMEM113(gene name synonym)|uniprotkb:TMEM113(gene name synonym)|uniprotkb:WDR82(gene name)|psi-mi:WDR82(display_short)|uniprotkb:Swd2(gene name synonym)|uniprotkb:WDR82A(gene name synonym)|uniprotkb:UNQ9342/PRO34047(orf name) psi-mi:set1a_human(display_long)|uniprotkb:KMT2F(gene name synonym)|uniprotkb:SET domain-containing protein 1A(gene name synonym)|uniprotkb:Set1/Ash2 histone methyltransferase complex subunit SET1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 2F(gene name synonym)|uniprotkb:SETD1A(gene name)|psi-mi:SETD1A(display_short)|uniprotkb:KIAA0339(gene name synonym)|uniprotkb:SET1(gene name synonym)|uniprotkb:SET1A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486793|imex:IM-26985-219 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079498.2|ensembl:ENSG00000164091(gene)|ensembl:ENST00000296490(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005730"(nucleolus)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|interpro:IPR037867|mint:Q6UXN9 refseq:NP_055527.1|refseq:XP_006721169.1|ensembl:ENSP00000262519|ensembl:ENSP00000507683|reactome:R-HSA-8936459|reactome:R-HSA-3214841|ensembl:ENSG00000099381(gene)|ensembl:ENST00000262519(transcript)|ensembl:ENST00000684162(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007420"(brain development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR024657|interpro:IPR034467|interpro:IPR035979|interpro:IPR037841|interpro:IPR044570|mint:O15047|go:"GO:0048188"(Set1C/COMPASS complex)|rcsb pdb:3S8S|rcsb pdb:3UVN|rcsb pdb:4EWR|refseq:XP_005255780.1|refseq:XP_016879398.1|dip:DIP-33494N - - comment:"author score: 27" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:0TyKYwpTLd22Cm+ihT1+n0oo12c9606 rogid:nx0uWEVFas1w2NmuG73lCObAULE9606 rigid:kJVxe3KFuY46057bOZAihX1fa4A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q6UXN9 uniprotkb:Q96QC0 intact:EBI-1176082|uniprotkb:Q8TEB2|uniprotkb:A8K5R5|intact:EBI-2562464|ensembl:ENSP00000296490 intact:EBI-1210346|uniprotkb:O00405|ensembl:ENSP00000365694|ensembl:ENSP00000373080|ensembl:ENSP00000389299|ensembl:ENSP00000407181|ensembl:ENSP00000407310|ensembl:ENSP00000413554|ensembl:ENSP00000416060 psi-mi:wdr82_human(display_long)|uniprotkb:Protein TMEM113(gene name synonym)|uniprotkb:TMEM113(gene name synonym)|uniprotkb:WDR82(gene name)|psi-mi:WDR82(display_short)|uniprotkb:Swd2(gene name synonym)|uniprotkb:WDR82A(gene name synonym)|uniprotkb:UNQ9342/PRO34047(orf name) psi-mi:pp1ra_human(display_long)|uniprotkb:PPP1R10(gene name)|psi-mi:PPP1R10(display_short)|uniprotkb:CAT53(gene name synonym)|uniprotkb:FB19(gene name synonym)|uniprotkb:PNUTS(gene name synonym)|uniprotkb:Phosphatase 1 nuclear targeting subunit(gene name synonym)|uniprotkb:MHC class I region proline-rich protein CAT53(gene name synonym)|uniprotkb:Protein FB19(gene name synonym)|uniprotkb:PP1-binding protein of 114 kDa(gene name synonym)|uniprotkb:p99(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486793|imex:IM-26985-219 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079498.2|ensembl:ENSG00000164091(gene)|ensembl:ENST00000296490(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005730"(nucleolus)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|interpro:IPR037867|mint:Q6UXN9 refseq:XP_011513024.1|refseq:NP_002705.2|refseq:XP_006715193.1|refseq:XP_016866484.1|dip:DIP-39343N|ensembl:ENSG00000204569(gene)|ensembl:ENSG00000206489(gene)|ensembl:ENSG00000227804(gene)|ensembl:ENSG00000230995(gene)|ensembl:ENSG00000231737(gene)|ensembl:ENSG00000235291(gene)|ensembl:ENSG00000238104(gene)|ensembl:ENST00000376511(transcript)|ensembl:ENST00000383586(transcript)|ensembl:ENST00000420949(transcript)|ensembl:ENST00000424446(transcript)|ensembl:ENST00000426299(transcript)|ensembl:ENST00000429597(transcript)|ensembl:ENST00000449113(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0010667"(negative regulation of cardiac muscle cell apoptotic process)|go:"GO:0016604"(nuclear body)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0046872"(metal ion binding)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:1904290"(negative regulation of mitotic DNA damage checkpoint)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR003617(Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type)|interpro:IPR017923|interpro:IPR035441|interpro:IPR036855|mint:Q96QC0|go:"GO:0000785"(chromatin) - - comment:"author score: 74" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:0TyKYwpTLd22Cm+ihT1+n0oo12c9606 rogid:ZWueXxqNFYPT0WhbfYdR3d2H2G89606 rigid:kJVxe3KFuY46057bOZAihX1fa4A false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9GZS3 uniprotkb:O60925 intact:EBI-358545|uniprotkb:D3DW84|uniprotkb:Q6IA22|uniprotkb:Q7Z4X4|ensembl:ENSP00000267973|ensembl:ENSP00000453801 intact:EBI-356919|uniprotkb:Q53F95|uniprotkb:Q96EX6|uniprotkb:B2RD02|ensembl:ENSP00000261813 psi-mi:wdr61_human(display_long)|uniprotkb:WDR61(gene name)|psi-mi:WDR61(display_short)|uniprotkb:Meiotic recombination REC14 protein homolog(gene name synonym)|uniprotkb:SKI8 homolog(gene name synonym) psi-mi:pfd1_human(display_long)|uniprotkb:PFDN1(gene name)|psi-mi:PFDN1(display_short)|uniprotkb:PFD1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486754|imex:IM-26985-455 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079510.1|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9GZS3|rcsb pdb:3OW8|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-429958|reactome:R-HSA-674695|reactome:R-HSA-75955|ensembl:ENSG00000140395(gene)|ensembl:ENST00000267973(transcript)|ensembl:ENST00000558311(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0055087"(Ski complex)|reactome:R-HSA-8866654|refseq:XP_011520396.1|refseq:NP_001290176.1|refseq:NP_001290177.1|dip:DIP-36672N refseq:NP_002613.2|ensembl:ENSG00000113068(gene)|ensembl:ENST00000261813(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|mint:O60925|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yVcjv2BXXr3VFSR7OcJ/1u9L6gw9606 rogid:repqo0hQgD7XgRAZll8ucK2jwz49606 rigid:/VuAAp2Lr0AxR/71F980p0HilkA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9GZS3 uniprotkb:O15212 intact:EBI-358545|uniprotkb:D3DW84|uniprotkb:Q6IA22|uniprotkb:Q7Z4X4|ensembl:ENSP00000267973|ensembl:ENSP00000453801 intact:EBI-356973|ensembl:ENSP00000363734|ensembl:ENSP00000363735|ensembl:ENSP00000363738|ensembl:ENSP00000372694|ensembl:ENSP00000378563|ensembl:ENSP00000382314|ensembl:ENSP00000382316|ensembl:ENSP00000395462|ensembl:ENSP00000398171|ensembl:ENSP00000400152|ensembl:ENSP00000402212|ensembl:ENSP00000402553|ensembl:ENSP00000403771|ensembl:ENSP00000404773|ensembl:ENSP00000412319|ensembl:ENSP00000415678|ensembl:ENSP00000447540|ensembl:ENSP00000448607|ensembl:ENSP00000448784|ensembl:ENSP00000449925 psi-mi:wdr61_human(display_long)|uniprotkb:WDR61(gene name)|psi-mi:WDR61(display_short)|uniprotkb:Meiotic recombination REC14 protein homolog(gene name synonym)|uniprotkb:SKI8 homolog(gene name synonym) psi-mi:pfd6_human(display_long)|uniprotkb:PFDN6(gene name)|psi-mi:PFDN6(display_short)|uniprotkb:HKE2(gene name synonym)|uniprotkb:PFD6(gene name synonym)|uniprotkb:Protein Ke2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486754|imex:IM-26985-455 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079510.1|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9GZS3|rcsb pdb:3OW8|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-429958|reactome:R-HSA-674695|reactome:R-HSA-75955|ensembl:ENSG00000140395(gene)|ensembl:ENST00000267973(transcript)|ensembl:ENST00000558311(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0055087"(Ski complex)|reactome:R-HSA-8866654|refseq:XP_011520396.1|refseq:NP_001290176.1|refseq:NP_001290177.1|dip:DIP-36672N refseq:NP_001172110.1|refseq:NP_055075.1|refseq:NP_001252524.1|refseq:NP_001252525.1|dip:DIP-50304N|ensembl:ENSG00000204220(gene)|ensembl:ENSG00000206283(gene)|ensembl:ENSG00000224782(gene)|ensembl:ENSG00000235692(gene)|ensembl:ENSG00000237335(gene)|ensembl:ENST00000374606(transcript)|ensembl:ENST00000374607(transcript)|ensembl:ENST00000374610(transcript)|ensembl:ENST00000383207(transcript)|ensembl:ENST00000395131(transcript)|ensembl:ENST00000399383(transcript)|ensembl:ENST00000399385(transcript)|ensembl:ENST00000412289(transcript)|ensembl:ENST00000425878(transcript)|ensembl:ENST00000431830(transcript)|ensembl:ENST00000432391(transcript)|ensembl:ENST00000442285(transcript)|ensembl:ENST00000445559(transcript)|ensembl:ENST00000448594(transcript)|ensembl:ENST00000451970(transcript)|ensembl:ENST00000452658(transcript)|ensembl:ENST00000547641(transcript)|ensembl:ENST00000547952(transcript)|ensembl:ENST00000548040(transcript)|ensembl:ENST00000552711(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|mint:O15212|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957 - - crc64:8F138EAAE512A312|comment:"author score: 36" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yVcjv2BXXr3VFSR7OcJ/1u9L6gw9606 rogid:t7Z68vuvmprxLIGDh4JhqCGvX+A9606 rigid:/VuAAp2Lr0AxR/71F980p0HilkA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9GZS3 uniprotkb:Q8WVC0 intact:EBI-358545|uniprotkb:D3DW84|uniprotkb:Q6IA22|uniprotkb:Q7Z4X4|ensembl:ENSP00000267973|ensembl:ENSP00000453801 intact:EBI-932432|uniprotkb:Q96N99|ensembl:ENSP00000299601 psi-mi:wdr61_human(display_long)|uniprotkb:WDR61(gene name)|psi-mi:WDR61(display_short)|uniprotkb:Meiotic recombination REC14 protein homolog(gene name synonym)|uniprotkb:SKI8 homolog(gene name synonym) psi-mi:leo1_human(display_long)|uniprotkb:LEO1(gene name)|psi-mi:LEO1(display_short)|uniprotkb:RDL(gene name synonym)|uniprotkb:Replicative senescence down-regulated leo1-like protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486754|imex:IM-26985-455 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079510.1|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9GZS3|rcsb pdb:3OW8|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-429958|reactome:R-HSA-674695|reactome:R-HSA-75955|ensembl:ENSG00000140395(gene)|ensembl:ENST00000267973(transcript)|ensembl:ENST00000558311(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0055087"(Ski complex)|reactome:R-HSA-8866654|refseq:XP_011520396.1|refseq:NP_001290176.1|refseq:NP_001290177.1|dip:DIP-36672N refseq:NP_001273359.1|refseq:NP_620147.1|dip:DIP-37885N|ensembl:ENSG00000166477(gene)|ensembl:ENST00000299601(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:1990269"(RNA polymerase II C-terminal domain phosphoserine binding)|interpro:IPR007149(Leo1-like protein)|mint:Q8WVC0|rcsb pdb:4M6T|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-201722|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654 - - comment:"author score: 36" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yVcjv2BXXr3VFSR7OcJ/1u9L6gw9606 rogid:o0aaW4nxzWuPZ8/pMZpa9Qz9oEA9606 rigid:/VuAAp2Lr0AxR/71F980p0HilkA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9GZS3 uniprotkb:Q99471 intact:EBI-358545|uniprotkb:D3DW84|uniprotkb:Q6IA22|uniprotkb:Q7Z4X4|ensembl:ENSP00000267973|ensembl:ENSP00000453801 intact:EBI-357275|ensembl:ENSP00000334188|ensembl:ENSP00000447942|intact:EBI-1047551|uniprotkb:A8K9A8|uniprotkb:Q54AA8|uniprotkb:Q9C083|uniprotkb:Q9C084 psi-mi:wdr61_human(display_long)|uniprotkb:WDR61(gene name)|psi-mi:WDR61(display_short)|uniprotkb:Meiotic recombination REC14 protein homolog(gene name synonym)|uniprotkb:SKI8 homolog(gene name synonym) psi-mi:pfd5_human(display_long)|uniprotkb:c-Myc-binding protein Mm-1(gene name synonym)|uniprotkb:PFDN5(gene name)|psi-mi:PFDN5(display_short)|uniprotkb:MM1(gene name synonym)|uniprotkb:Myc modulator 1(gene name synonym)|uniprotkb:PFD5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486754|imex:IM-26985-455 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079510.1|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9GZS3|rcsb pdb:3OW8|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-429958|reactome:R-HSA-674695|reactome:R-HSA-75955|ensembl:ENSG00000140395(gene)|ensembl:ENST00000267973(transcript)|ensembl:ENST00000558311(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0055087"(Ski complex)|reactome:R-HSA-8866654|refseq:XP_011520396.1|refseq:NP_001290176.1|refseq:NP_001290177.1|dip:DIP-36672N ensembl:ENSG00000123349(gene)|ensembl:ENST00000334478(transcript)|ensembl:ENST00000551018(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR011599(Prefoldin alpha subunit)|mint:Q99471|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957|refseq:NP_002615.2|refseq:NP_665904.1|dip:DIP-28155N - - comment:"author score: 41" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yVcjv2BXXr3VFSR7OcJ/1u9L6gw9606 rogid:Cm4km207qcfDJYRUCIwUxMBT4tE9606 rigid:/VuAAp2Lr0AxR/71F980p0HilkA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9GZS3 uniprotkb:Q9UHV9 intact:EBI-358545|uniprotkb:D3DW84|uniprotkb:Q6IA22|uniprotkb:Q7Z4X4|ensembl:ENSP00000267973|ensembl:ENSP00000453801 intact:EBI-359873|uniprotkb:Q9P0P7|uniprotkb:Q9UN05|ensembl:ENSP00000356989 psi-mi:wdr61_human(display_long)|uniprotkb:WDR61(gene name)|psi-mi:WDR61(display_short)|uniprotkb:Meiotic recombination REC14 protein homolog(gene name synonym)|uniprotkb:SKI8 homolog(gene name synonym) psi-mi:pfd2_human(display_long)|uniprotkb:HSPC231(orf name)|uniprotkb:PFDN2(gene name)|psi-mi:PFDN2(display_short)|uniprotkb:PFD2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486754|imex:IM-26985-455 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079510.1|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9GZS3|rcsb pdb:3OW8|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-429958|reactome:R-HSA-674695|reactome:R-HSA-75955|ensembl:ENSG00000140395(gene)|ensembl:ENST00000267973(transcript)|ensembl:ENST00000558311(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0055087"(Ski complex)|reactome:R-HSA-8866654|refseq:XP_011520396.1|refseq:NP_001290176.1|refseq:NP_001290177.1|dip:DIP-36672N refseq:NP_036526.2|refseq:XP_011507926.1|ensembl:ENSG00000143256(gene)|ensembl:ENST00000368010(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051495"(positive regulation of cytoskeleton organization)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|interpro:IPR027235|mint:Q9UHV9|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957|dip:DIP-27557N - - comment:"author score: 42" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yVcjv2BXXr3VFSR7OcJ/1u9L6gw9606 rogid:rgr14h3vGyzHxHoNJtlHBQkvhUE9606 rigid:/VuAAp2Lr0AxR/71F980p0HilkA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9GZS3 uniprotkb:Q6PID6 intact:EBI-358545|uniprotkb:D3DW84|uniprotkb:Q6IA22|uniprotkb:Q7Z4X4|ensembl:ENSP00000267973|ensembl:ENSP00000453801 intact:EBI-2555404|uniprotkb:O95105|uniprotkb:B2R6G0|ensembl:ENSP00000338533 psi-mi:wdr61_human(display_long)|uniprotkb:WDR61(gene name)|psi-mi:WDR61(display_short)|uniprotkb:Meiotic recombination REC14 protein homolog(gene name synonym)|uniprotkb:SKI8 homolog(gene name synonym) psi-mi:ttc33_human(display_long)|uniprotkb:Osmosis-responsive factor(gene name synonym)|uniprotkb:TTC33(gene name)|psi-mi:TTC33(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486754|imex:IM-26985-455 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079510.1|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9GZS3|rcsb pdb:3OW8|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-429958|reactome:R-HSA-674695|reactome:R-HSA-75955|ensembl:ENSG00000140395(gene)|ensembl:ENST00000267973(transcript)|ensembl:ENST00000558311(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0055087"(Ski complex)|reactome:R-HSA-8866654|refseq:XP_011520396.1|refseq:NP_001290176.1|refseq:NP_001290177.1|dip:DIP-36672N refseq:NP_036514.1|refseq:XP_011512305.1|ensembl:ENSG00000113638(gene)|ensembl:ENST00000337702(transcript)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|mint:Q6PID6 - - comment:"author score: 42" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yVcjv2BXXr3VFSR7OcJ/1u9L6gw9606 rogid:E83noPN1tHU7Ow6YNDDE+vuJkHo9606 rigid:/VuAAp2Lr0AxR/71F980p0HilkA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9GZS3 uniprotkb:P61758 intact:EBI-358545|uniprotkb:D3DW84|uniprotkb:Q6IA22|uniprotkb:Q7Z4X4|ensembl:ENSP00000267973|ensembl:ENSP00000453801 intact:EBI-357430|ensembl:ENSP00000286428|uniprotkb:Q15765|uniprotkb:O55228|uniprotkb:Q5JT81|uniprotkb:Q86X96|uniprotkb:B2R8L5|uniprotkb:B4DWR3|uniprotkb:F5H2A7 psi-mi:wdr61_human(display_long)|uniprotkb:WDR61(gene name)|psi-mi:WDR61(display_short)|uniprotkb:Meiotic recombination REC14 protein homolog(gene name synonym)|uniprotkb:SKI8 homolog(gene name synonym) psi-mi:pfd3_human(display_long)|uniprotkb:VBP1(gene name)|psi-mi:VBP1(display_short)|uniprotkb:PFDN3(gene name synonym)|uniprotkb:von Hippel-Lindau-binding protein 1(gene name synonym)|uniprotkb:HIBBJ46(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486754|imex:IM-26985-455 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079510.1|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9GZS3|rcsb pdb:3OW8|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-429958|reactome:R-HSA-674695|reactome:R-HSA-75955|ensembl:ENSG00000140395(gene)|ensembl:ENST00000267973(transcript)|ensembl:ENST00000558311(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0055087"(Ski complex)|reactome:R-HSA-8866654|refseq:XP_011520396.1|refseq:NP_001290176.1|refseq:NP_001290177.1|dip:DIP-36672N ensembl:ENSG00000155959(gene)|ensembl:ENST00000286428(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006457"(protein folding)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007021"(tubulin complex assembly)|go:"GO:0015631"(tubulin binding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051082"(unfolded protein binding)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR004127(Prefoldin alpha-like)|interpro:IPR009053(Prefoldin)|interpro:IPR016655(Prefoldin, subunit 3)|mint:P61758|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957|refseq:NP_003363.1|refseq:NP_001290472.1|refseq:NP_001290474.1|dip:DIP-46479N|refseq:NP_001290473.1 - - comment:"author score: 44" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yVcjv2BXXr3VFSR7OcJ/1u9L6gw9606 rogid:wHq+HRvhqfKwOaKtONGJdfETQxo9606 rigid:/VuAAp2Lr0AxR/71F980p0HilkA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9GZS3 uniprotkb:Q6PGP7 intact:EBI-358545|uniprotkb:D3DW84|uniprotkb:Q6IA22|uniprotkb:Q7Z4X4|ensembl:ENSP00000267973|ensembl:ENSP00000453801 intact:EBI-6083436|uniprotkb:O15077|uniprotkb:Q6PJI3|ensembl:ENSP00000351596|ensembl:ENSP00000497948 psi-mi:wdr61_human(display_long)|uniprotkb:WDR61(gene name)|psi-mi:WDR61(display_short)|uniprotkb:Meiotic recombination REC14 protein homolog(gene name synonym)|uniprotkb:SKI8 homolog(gene name synonym) psi-mi:ttc37_human(display_long)|uniprotkb:Tricho-hepatic-enteric syndrome protein(gene name synonym)|uniprotkb:SKI3 homolog(gene name synonym)|uniprotkb:TTC37(gene name)|psi-mi:TTC37(display_short)|uniprotkb:KIAA0372(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486754|imex:IM-26985-455 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079510.1|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9GZS3|rcsb pdb:3OW8|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-429958|reactome:R-HSA-674695|reactome:R-HSA-75955|ensembl:ENSG00000140395(gene)|ensembl:ENST00000267973(transcript)|ensembl:ENST00000558311(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0055087"(Ski complex)|reactome:R-HSA-8866654|refseq:XP_011520396.1|refseq:NP_001290176.1|refseq:NP_001290177.1|dip:DIP-36672N refseq:NP_055454.1|ensembl:ENSG00000198677(gene)|ensembl:ENST00000358746(transcript)|ensembl:ENST00000649566(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0034427"(nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5')|go:"GO:0035327"|go:"GO:0055087"(Ski complex)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR039226|mint:Q6PGP7|reactome:R-HSA-429958 - - comment:"author score: 57" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yVcjv2BXXr3VFSR7OcJ/1u9L6gw9606 rogid:1vbt+NR8Vmwq7a+9fisoF2WxDbc9606 rigid:/VuAAp2Lr0AxR/71F980p0HilkA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9GZS3 uniprotkb:Q15477 intact:EBI-358545|uniprotkb:D3DW84|uniprotkb:Q6IA22|uniprotkb:Q7Z4X4|ensembl:ENSP00000267973|ensembl:ENSP00000453801 intact:EBI-373226|uniprotkb:O15005|uniprotkb:Q12902|uniprotkb:Q15476|intact:EBI-1058949|uniprotkb:Q5ST66|ensembl:ENSP00000364543|ensembl:ENSP00000372827|ensembl:ENSP00000394400|ensembl:ENSP00000399530|ensembl:ENSP00000400626|ensembl:ENSP00000412310 psi-mi:wdr61_human(display_long)|uniprotkb:WDR61(gene name)|psi-mi:WDR61(display_short)|uniprotkb:Meiotic recombination REC14 protein homolog(gene name synonym)|uniprotkb:SKI8 homolog(gene name synonym) psi-mi:skiv2_human(display_long)|uniprotkb:SKIV2L(gene name)|psi-mi:SKIV2L(display_short)|uniprotkb:DDX13(gene name synonym)|uniprotkb:SKI2W(gene name synonym)|uniprotkb:SKIV2(gene name synonym)|uniprotkb:W(gene name synonym)|uniprotkb:Helicase-like protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486754|imex:IM-26985-455 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079510.1|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9GZS3|rcsb pdb:3OW8|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-429958|reactome:R-HSA-674695|reactome:R-HSA-75955|ensembl:ENSG00000140395(gene)|ensembl:ENST00000267973(transcript)|ensembl:ENST00000558311(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0055087"(Ski complex)|reactome:R-HSA-8866654|refseq:XP_011520396.1|refseq:NP_001290176.1|refseq:NP_001290177.1|dip:DIP-36672N refseq:NP_008860.4|ensembl:ENSG00000204351(gene)|ensembl:ENSG00000206353(gene)|ensembl:ENSG00000223493(gene)|ensembl:ENSG00000225737(gene)|ensembl:ENSG00000228896(gene)|ensembl:ENSG00000232616(gene)|ensembl:ENST00000375394(transcript)|ensembl:ENST00000383336(transcript)|ensembl:ENST00000412823(transcript)|ensembl:ENST00000421789(transcript)|ensembl:ENST00000429465(transcript)|ensembl:ENST00000448219(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0055087"(Ski complex)|go:"GO:0070478"(nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR012961(DSH, C-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR016438(RNA helicase, ATP-dependent, SK12/DOB1)|interpro:IPR025696|interpro:IPR027417|interpro:IPR040801|mint:Q15477|reactome:R-HSA-390471|reactome:R-HSA-429958 - - comment:"author score: 63" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yVcjv2BXXr3VFSR7OcJ/1u9L6gw9606 rogid:+42a3/XPqsM8hc3qP2M9n/pZ+bY9606 rigid:/VuAAp2Lr0AxR/71F980p0HilkA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9GZS3 uniprotkb:Q9NQP4 intact:EBI-358545|uniprotkb:D3DW84|uniprotkb:Q6IA22|uniprotkb:Q7Z4X4|ensembl:ENSP00000267973|ensembl:ENSP00000453801 intact:EBI-357021|uniprotkb:Q5TD11|uniprotkb:Q92779|ensembl:ENSP00000360473 psi-mi:wdr61_human(display_long)|uniprotkb:WDR61(gene name)|psi-mi:WDR61(display_short)|uniprotkb:Meiotic recombination REC14 protein homolog(gene name synonym)|uniprotkb:SKI8 homolog(gene name synonym) psi-mi:pfd4_human(display_long)|uniprotkb:PFDN4(gene name)|psi-mi:PFDN4(display_short)|uniprotkb:PFD4(gene name synonym)|uniprotkb:Protein C-1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486754|imex:IM-26985-455 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079510.1|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9GZS3|rcsb pdb:3OW8|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-429958|reactome:R-HSA-674695|reactome:R-HSA-75955|ensembl:ENSG00000140395(gene)|ensembl:ENST00000267973(transcript)|ensembl:ENST00000558311(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0055087"(Ski complex)|reactome:R-HSA-8866654|refseq:XP_011520396.1|refseq:NP_001290176.1|refseq:NP_001290177.1|dip:DIP-36672N refseq:NP_002614.2|ensembl:ENSG00000101132(gene)|ensembl:ENST00000371419(transcript)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0016272"(prefoldin complex)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051087"(chaperone binding)|go:"GO:1905907"(negative regulation of amyloid fibril formation)|interpro:IPR002777(Prefoldin beta-like)|interpro:IPR009053(Prefoldin)|interpro:IPR016661(Prefoldin, subunit 4)|mint:Q9NQP4|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|reactome:R-HSA-389957 - - comment:"author score: 67" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yVcjv2BXXr3VFSR7OcJ/1u9L6gw9606 rogid:oXbJiHxqcYHrAWGGgzV81ocGt889606 rigid:/VuAAp2Lr0AxR/71F980p0HilkA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q9GZS3 uniprotkb:Q8N7H5 intact:EBI-358545|uniprotkb:D3DW84|uniprotkb:Q6IA22|uniprotkb:Q7Z4X4|ensembl:ENSP00000267973|ensembl:ENSP00000453801 intact:EBI-2607770|uniprotkb:O75239|uniprotkb:Q9H166|uniprotkb:Q9NUU9|ensembl:ENSP00000221265|uniprotkb:M0QX35 psi-mi:wdr61_human(display_long)|uniprotkb:WDR61(gene name)|psi-mi:WDR61(display_short)|uniprotkb:Meiotic recombination REC14 protein homolog(gene name synonym)|uniprotkb:SKI8 homolog(gene name synonym) psi-mi:paf1_human(display_long)|uniprotkb:PAF1(gene name)|psi-mi:PAF1(display_short)|uniprotkb:PD2(gene name synonym)|uniprotkb:Pancreatic differentiation protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486754|imex:IM-26985-455 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_079510.1|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:2001162"(positive regulation of histone H3-K79 methylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:Q9GZS3|rcsb pdb:3OW8|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-429958|reactome:R-HSA-674695|reactome:R-HSA-75955|ensembl:ENSG00000140395(gene)|ensembl:ENST00000267973(transcript)|ensembl:ENST00000558311(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0055087"(Ski complex)|reactome:R-HSA-8866654|refseq:XP_011520396.1|refseq:NP_001290176.1|refseq:NP_001290177.1|dip:DIP-36672N refseq:NP_061961.2|ensembl:ENSG00000006712(gene)|ensembl:ENST00000221265(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000993"(RNA polymerase II complex binding)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0003682"(chromatin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0006378"(mRNA polyadenylation)|go:"GO:0010390"(histone monoubiquitination)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0016593"(Cdc73/Paf1 complex)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0030054"(cell junction)|go:"GO:0031062"(positive regulation of histone methylation)|go:"GO:0031442"(positive regulation of mRNA 3'-end processing)|go:"GO:0033523"(histone H2B ubiquitination)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0035327"|go:"GO:0045638"(negative regulation of myeloid cell differentiation)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR007133(RNA polymerase II-associated, Paf1)|mint:Q8N7H5|rcsb pdb:4M6T|rcsb pdb:5ZYQ|rcsb pdb:6GMH|rcsb pdb:6TED|reactome:R-HSA-112382|reactome:R-HSA-674695|reactome:R-HSA-75955|reactome:R-HSA-8866654|refseq:NP_001243755.1|dip:DIP-48673N - - comment:"author score: 111" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:yVcjv2BXXr3VFSR7OcJ/1u9L6gw9606 rogid:5Bf9gSdxgaufI30DVL8QAyVLqNk9606 rigid:/VuAAp2Lr0AxR/71F980p0HilkA false tandem tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q9ULD9 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-15637608|ensembl:ENSP00000307746|ensembl:ENSP00000421899|uniprotkb:A7E2W9|uniprotkb:Q3SYM6|uniprotkb:Q68D12|uniprotkb:Q8IY05|uniprotkb:Q9Y5A1 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:zn608_human(display_long)|uniprotkb:ZNF608(gene name)|psi-mi:ZNF608(display_short)|uniprotkb:KIAA1281(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-36(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486637|imex:IM-26985-297 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N ensembl:ENSG00000168916(gene)|ensembl:ENST00000306315(transcript)|ensembl:ENST00000513986(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR040010|mint:Q9ULD9|ensembl:ENSP00000307746|ensembl:ENST00000504926|ensembl:ENSP00000427657|ensembl:ENSP00000421899|refseq:NP_065798.2|refseq:XP_005272094.1|refseq:XP_005272095.1|dip:DIP-29419N - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:Zh0o9HcH3q3xBtISrHQz2LOS7kI9606 rigid:T7MB0QjLpFWfhqYD3ZAvxofpau0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q8NFC6 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-2654318|uniprotkb:Q9NTD6|uniprotkb:Q96AL1|uniprotkb:Q9H6G0|uniprotkb:Q6P0M8|uniprotkb:Q9P2L9|ensembl:ENSP00000040738 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:bd1l1_human(display_long)|uniprotkb:BOD1L1(gene name)|psi-mi:BOD1L1(display_short)|uniprotkb:BOD1L(gene name synonym)|uniprotkb:FAM44A(gene name synonym)|uniprotkb:KIAA1327(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486637|imex:IM-26985-297 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N refseq:NP_683692.2|ensembl:ENSG00000038219(gene)|ensembl:ENST00000040738(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0000940"(outer kinetochore)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005876"(spindle microtubule)|go:"GO:0006281"(DNA repair)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0031297"(replication fork processing)|go:"GO:0032515"(negative regulation of phosphoprotein phosphatase activity)|go:"GO:0051721"(protein phosphatase 2A binding)|interpro:IPR043244|mint:Q8NFC6 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:/sFfw7CP8rOZG3hZNsT0npwIZIQ9606 rigid:T7MB0QjLpFWfhqYD3ZAvxofpau0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q99496 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-722416|uniprotkb:Q5TEN1|uniprotkb:Q5TEN2|uniprotkb:B2RBS7|uniprotkb:B3KRH1|ensembl:ENSP00000356480 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:ring2_human(display_long)|uniprotkb:RING finger protein 2(gene name synonym)|uniprotkb:RING finger protein 1B(gene name synonym)|uniprotkb:RING finger protein BAP-1(gene name synonym)|uniprotkb:Protein DinG(gene name synonym)|uniprotkb:Huntingtin-interacting protein 2-interacting protein 3(gene name synonym)|uniprotkb:RNF2(gene name)|psi-mi:RNF2(display_short)|uniprotkb:BAP1(gene name synonym)|uniprotkb:DING(gene name synonym)|uniprotkb:HIPI3(gene name synonym)|uniprotkb:RING1B(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase RING2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486637|imex:IM-26985-297 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N refseq:NP_009143.1|refseq:XP_011508153.1|refseq:XP_011508154.1|dip:DIP-40034N|ensembl:ENSG00000121481(gene)|ensembl:ENST00000367510(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000791"(euchromatin)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001739"(sex chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007281"(germ cell development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0010467"(gene expression)|go:"GO:0016604"(nuclear body)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0035518"(histone H2A monoubiquitination)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071535"(RING-like zinc finger domain binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR032443|interpro:IPR037937|interpro:IPR043540|mint:Q99496|rcsb pdb:2H0D|rcsb pdb:3GS2|rcsb pdb:3H8H|rcsb pdb:3IXS|rcsb pdb:3RPG|rcsb pdb:4R8P|rcsb pdb:4S3O|rcsb pdb:7ND1|reactome:R-HSA-2559580|reactome:R-HSA-3108214|reactome:R-HSA-3899300|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4655427|reactome:R-HSA-8939243|reactome:R-HSA-8943724|reactome:R-HSA-8953750 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:pqAjSEwOUdfuogKW6fodqsUSHIk9606 rigid:T7MB0QjLpFWfhqYD3ZAvxofpau0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q9BVI0 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-2560802|intact:EBI-3962525|uniprotkb:Q566Q2|uniprotkb:Q66K49|uniprotkb:A7E235|uniprotkb:Q9H4J6|uniprotkb:Q9BXA3|uniprotkb:B2RB56|uniprotkb:Q9BZW3|uniprotkb:Q9NZ22|uniprotkb:Q9BWV4|uniprotkb:Q9H421|uniprotkb:Q5JWY9|uniprotkb:E1P5S3|ensembl:ENSP00000363124 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:phf20_human(display_long)|uniprotkb:Transcription factor TZP(gene name synonym)|uniprotkb:Novel zinc finger protein(gene name synonym)|uniprotkb:PHF20(gene name)|psi-mi:PHF20(display_short)|uniprotkb:C20orf104(gene name synonym)|uniprotkb:GLEA2(gene name synonym)|uniprotkb:HCA58(gene name synonym)|uniprotkb:NZF(gene name synonym)|uniprotkb:TZP(gene name synonym)|uniprotkb:Hepatocellular carcinoma-associated antigen 58(gene name synonym)|uniprotkb:Glioma-expressed antigen 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486637|imex:IM-26985-297 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N refseq:NP_057520.2|ensembl:ENSG00000025293(gene)|ensembl:ENST00000374012(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016573"(histone acetylation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044545"(NSL complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002999(Tudor)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR019786|interpro:IPR022255|interpro:IPR037915|interpro:IPR041297|interpro:IPR043449|mint:Q9BVI0|rcsb pdb:2LDM|rcsb pdb:3P8D|rcsb pdb:3Q1J|rcsb pdb:3QII|rcsb pdb:3SD4|rcsb pdb:5TAB|rcsb pdb:5TBN|reactome:R-HSA-3214847|reactome:R-HSA-6804757|reactome:R-HSA-6804759|reactome:R-HSA-69541|refseq:XP_016883353.1|refseq:XP_016883354.1|refseq:XP_016883355.1|refseq:XP_016883356.1 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:xyUU6acdr5R0gcqvCc20L15+lto9606 rigid:T7MB0QjLpFWfhqYD3ZAvxofpau0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:A8MW92 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-2560834|uniprotkb:Q9H702|uniprotkb:Q86W43|uniprotkb:A8MZC9|uniprotkb:Q96BT0|uniprotkb:Q9HBK3|uniprotkb:Q9NYR3|uniprotkb:Q9Y381|intact:EBI-2797510|uniprotkb:Q86U89|ensembl:ENSP00000378784|ensembl:ENSP00000482945 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:p20l1_human(display_long)|uniprotkb:PHF20L1(gene name)|psi-mi:PHF20L1(display_short)|uniprotkb:CGI-72(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486637|imex:IM-26985-297 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N refseq:NP_057102.4|refseq:NP_940915.1|ensembl:ENSG00000129292(gene)|ensembl:ENST00000395386(transcript)|ensembl:ENST00000622263(transcript)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016573"(histone acetylation)|go:"GO:0044545"(NSL complex)|go:"GO:0046872"(metal ion binding)|interpro:IPR002999(Tudor)|interpro:IPR004092(Mbt repeat)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014002(Tudor-like, plant)|interpro:IPR019786|interpro:IPR022255|interpro:IPR040477|interpro:IPR043449|mint:A8MW92|rcsb pdb:2EQM|rcsb pdb:2EQU|rcsb pdb:2JTF|rcsb pdb:6L10|rcsb pdb:6L1C|rcsb pdb:6L1F|rcsb pdb:6L1I|rcsb pdb:6L1P|rcsb pdb:6L0X|refseq:XP_016869006.1 - - comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:rkzmf0OHtpMATZ2P0uhZu0GR94E9606 rigid:T7MB0QjLpFWfhqYD3ZAvxofpau0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:P54259 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-945980|uniprotkb:Q99495|uniprotkb:Q99621|uniprotkb:Q9UEK7|ensembl:ENSP00000349076|ensembl:ENSP00000379915 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:atn1_human(display_long)|uniprotkb:ATN1(gene name)|psi-mi:ATN1(display_short)|uniprotkb:DRPLA(gene name synonym)|uniprotkb:Dentatorubral-pallidoluysian atrophy protein(gene name synonym)|uniprotkb:D12S755E(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486637|imex:IM-26985-297 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N refseq:NP_001007027.1|refseq:NP_001931.2|ensembl:ENSP00000349076|ensembl:ENSP00000379915|dip:DIP-29423N|ensembl:ENSG00000111676(gene)|ensembl:ENST00000356654(transcript)|ensembl:ENST00000396684(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0007417"(central nervous system development)|go:"GO:0016363"(nuclear matrix)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR002951(Atrophin)|interpro:IPR017993|mint:P54259|reactome:R-HSA-8943724 - - crc64:B47603486C672637|comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:SX8MuZ4aW8/PJmQl4HqY+NOSxbI9606 rigid:T7MB0QjLpFWfhqYD3ZAvxofpau0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q9H7Z6 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-896414|uniprotkb:Q659G0|uniprotkb:Q7LC17|uniprotkb:Q8IY59|uniprotkb:Q8WYB4|uniprotkb:Q8WZ14|uniprotkb:Q9HAC5|uniprotkb:Q9NR35|uniprotkb:A8K4Z1|intact:EBI-2560822|uniprotkb:G5E9P2|ensembl:ENSP00000219797|ensembl:ENSP00000456933 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:kat8_human(display_long)|uniprotkb:KAT8(gene name)|psi-mi:KAT8(display_short)|uniprotkb:MOF(gene name synonym)|uniprotkb:PP7073(orf name)|uniprotkb:MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1(gene name synonym)|uniprotkb:MYST1(gene name synonym)|uniprotkb:Lysine acetyltransferase 8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486637|imex:IM-26985-297 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N refseq:NP_115564.2|refseq:NP_892003.2|ensembl:ENSG00000103510(gene)|ensembl:ENST00000219797(transcript)|ensembl:ENST00000543774(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000776"(kinetochore)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016407"(acetyltransferase activity)|go:"GO:0016573"(histone acetylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0035064"(methylated histone binding)|go:"GO:0042393"(histone binding)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0043995"("histone acetyltransferase activity (H4-K5 specific)")|go:"GO:0043996"("histone acetyltransferase activity (H4-K8 specific)")|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046972"("histone acetyltransferase activity (H4-K16 specific)")|go:"GO:0071339"(MLL1 complex)|go:"GO:0072487"(MSL complex)|interpro:IPR000953(Chromo domain)|interpro:IPR002717(MOZ/SAS-like protein)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR016197(Chromo domain-like)|interpro:IPR025995|interpro:IPR036388|interpro:IPR037906|interpro:IPR040706|mint:Q9H7Z6|rcsb pdb:2GIV|rcsb pdb:2PQ8|rcsb pdb:2Y0M|rcsb pdb:3QAH|rcsb pdb:3TOA|rcsb pdb:3TOB|rcsb pdb:4DNC|rcsb pdb:5H43|rcsb pdb:5J8C|rcsb pdb:5J8F|rcsb pdb:5WCI|rcsb pdb:6BA2|rcsb pdb:6BA4|rcsb pdb:6CT2|rcsb pdb:6OIN|rcsb pdb:6OIO|rcsb pdb:6OIP|rcsb pdb:6OIQ|rcsb pdb:6OIR|rcsb pdb:6OWH|rcsb pdb:6OWI|rcsb pdb:6PD8|rcsb pdb:6PD9|rcsb pdb:6PDA|rcsb pdb:6PDB|rcsb pdb:6PDC|rcsb pdb:6PDD|rcsb pdb:6PDE|rcsb pdb:6PDF|rcsb pdb:6PDG|rcsb pdb:7CMR|reactome:R-HSA-3214847 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:CIkEOWd9OuFyigFJ02ORCqVbXHE9606 rigid:T7MB0QjLpFWfhqYD3ZAvxofpau0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:O43684 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-1050987|uniprotkb:O43685|uniprotkb:B2R6E7|uniprotkb:A6NJ42|uniprotkb:D3DRE9|ensembl:ENSP00000357858 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:bub3_human(display_long)|uniprotkb:BUB3(gene name)|psi-mi:BUB3(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486637|imex:IM-26985-297 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N refseq:NP_001007794.1|refseq:NP_004716.1|ensembl:ENSG00000154473(gene)|ensembl:ENST00000368865(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000776"(kinetochore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR020472|interpro:IPR036322|mint:O43684|reactome:R-HSA-141430|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|reactome:R-HSA-141444|reactome:R-HSA-174184|reactome:R-HSA-176409|reactome:R-HSA-179409|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|go:"GO:0008608"(attachment of spindle microtubules to kinetochore)|reactome:R-HSA-68877|reactome:R-HSA-9648025|go:"GO:0033597"(mitotic checkpoint complex)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0051301"(cell division)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:1990298"(bub1-bub3 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|dip:DIP-24205N - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:nqzARPql2cThSUpxSb6PuTRn51E9606 rigid:T7MB0QjLpFWfhqYD3ZAvxofpau0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q9UPS6 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-8836493|uniprotkb:F6MFW1|ensembl:ENSP00000474253|ensembl:ENSP00000481531 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:set1b_human(display_long)|uniprotkb:KIAA1076(gene name synonym)|uniprotkb:KMT2G(gene name synonym)|uniprotkb:Lysine N-methyltransferase 2G(gene name synonym)|uniprotkb:SET domain-containing protein 1B(gene name synonym)|uniprotkb:SET1B(gene name synonym)|uniprotkb:SETD1B(gene name)|psi-mi:SETD1B(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486637|imex:IM-26985-297 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N refseq:NP_055863.1|ensembl:ENST00000542440|ensembl:ENSP00000442924|ensembl:ENSP00000474253|ensembl:ENSP00000481531|refseq:XP_005253915.1|refseq:XP_006719359.1|dip:DIP-61947N|go:"GO:0097692"(histone H3-K4 monomethylation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR024657|interpro:IPR034468|interpro:IPR035979|interpro:IPR037842|interpro:IPR044570|ensembl:ENSG00000139718(gene)|ensembl:ENST00000604567(transcript)|ensembl:ENST00000619791(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0016607"(nuclear speck)|go:"GO:0018024"(histone-lysine N-methyltransferase activity)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|mint:Q9UPS6|rcsb pdb:3UVO|rcsb pdb:4ES0|reactome:R-HSA-3214841|reactome:R-HSA-8936459 - - comment:"author score: 19" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:ZUY82C1+39tPg4n/f61PDe3DlGo9606 rigid:T7MB0QjLpFWfhqYD3ZAvxofpau0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:O75528 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-473249|uniprotkb:Q9UFS2|intact:EBI-28973289|ensembl:ENSP00000307684|ensembl:ENSP00000393471|uniprotkb:Q6FI83 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:tada3_human(display_long)|uniprotkb:ADA3 homolog(gene name synonym)|uniprotkb:STAF54(gene name synonym)|uniprotkb:TADA3(gene name)|psi-mi:TADA3(display_short)|uniprotkb:ADA3(gene name synonym)|uniprotkb:TADA3L(gene name synonym)|uniprotkb:Transcriptional adapter 3-like(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486637|imex:IM-26985-297 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N ensembl:ENSG00000171148(gene)|ensembl:ENST00000301964(transcript)|ensembl:ENST00000440161(transcript)|go:"GO:0000124"(SAGA complex)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0030520"(intracellular estrogen receptor signaling pathway)|go:"GO:0030914"|go:"GO:0031063"(regulation of histone deacetylation)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0033276"(transcription factor TFTC complex)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090043"(regulation of tubulin deacetylation)|interpro:IPR019340|mint:O75528|reactome:R-HSA-3214847|reactome:R-HSA-5689880|ensembl:ENSP00000307684|ensembl:ENST00000343450|ensembl:ENSP00000343649|ensembl:ENSP00000393471|refseq:NP_006345.1|refseq:NP_597814.1|refseq:NP_001265199.1 - - comment:"author score: 21" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:5NQkQiw+G/8uL2fjoMgW8+mTB8o9606 rigid:T7MB0QjLpFWfhqYD3ZAvxofpau0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:P61513 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-356793|uniprotkb:P12751|intact:EBI-1051378|uniprotkb:Q6FGF5|ensembl:ENSP00000418082 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:rl37a_human(display_long)|uniprotkb:RPL37A(gene name)|psi-mi:RPL37A(display_short)|uniprotkb:Large ribosomal subunit protein eL43(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486637|imex:IM-26985-297 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N refseq:NP_000989.1|ensembl:ENSG00000197756(gene)|ensembl:ENST00000491306(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002674(Ribosomal protein L37ae)|interpro:IPR011331(Ribosomal protein L37ae/L37e, core)|interpro:IPR011332(Ribosomal protein, zinc-binding)|mint:P61513|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:0kwO2cVd99FGF2+5FyWo94C83049606 rigid:T7MB0QjLpFWfhqYD3ZAvxofpau0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:O00255 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-592789|uniprotkb:O00632|uniprotkb:Q9BUK2|uniprotkb:A5HBC6|uniprotkb:A5HBC7|uniprotkb:A5HBC8|uniprotkb:A5HBC9|uniprotkb:A5HBD0|uniprotkb:A5HBD1|uniprotkb:A5HBD2|uniprotkb:Q9BUF0|ensembl:ENSP00000366530 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:men1_human(display_long)|uniprotkb:MEN1(gene name)|psi-mi:MEN1(display_short)|uniprotkb:SCG2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486637|imex:IM-26985-297 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N refseq:NP_000235.2|refseq:NP_570711.1|refseq:NP_570712.1|refseq:NP_570713.1|refseq:NP_570714.1|refseq:NP_570715.1|refseq:NP_570716.1|refseq:XP_005274058.1|refseq:XP_016873258.1|refseq:XP_016873259.1|dip:DIP-24236N|ensembl:ENSG00000133895(gene)|ensembl:ENST00000377313(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000165"(MAPK cascade)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000403"(Y-form DNA binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002076"(osteoblast development)|go:"GO:0003309"(type B pancreatic cell differentiation)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009411"(response to UV)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032925"(regulation of activin receptor signaling pathway)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045736"(negative regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0046697"(decidualization)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0061469"(regulation of type B pancreatic cell proliferation)|go:"GO:0070412"(R-SMAD binding)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071559"(response to transforming growth factor beta)|go:"GO:1902807"(negative regulation of cell cycle G1/S phase transition)|interpro:IPR007747(Menin)|mint:O00255|rcsb pdb:3U84|rcsb pdb:3U85|rcsb pdb:3U86|rcsb pdb:3U88|rcsb pdb:4GPQ|rcsb pdb:4GQ3|rcsb pdb:4GQ4|rcsb pdb:4GQ6|rcsb pdb:4I80|rcsb pdb:4OG3|rcsb pdb:4OG4|rcsb pdb:4OG5|rcsb pdb:4OG6|rcsb pdb:4OG7|rcsb pdb:4OG8|rcsb pdb:4X5Y|rcsb pdb:4X5Z|rcsb pdb:5DB0|rcsb pdb:5DB1|rcsb pdb:5DB2|rcsb pdb:5DB3|rcsb pdb:5DD9|rcsb pdb:5DDA|rcsb pdb:5DDB|rcsb pdb:5DDC|rcsb pdb:5DDD|rcsb pdb:5DDF|rcsb pdb:6B41|rcsb pdb:6BXH|rcsb pdb:6BXY|rcsb pdb:6BY8|rcsb pdb:6E1A|rcsb pdb:6O5I|rcsb pdb:6OPJ|rcsb pdb:6PKC|rcsb pdb:6WNH|reactome:R-HSA-201722|reactome:R-HSA-2173796|reactome:R-HSA-3769402|reactome:R-HSA-381426|reactome:R-HSA-5626467|reactome:R-HSA-8957275|rcsb pdb:5DDE - - comment:"author score: 25" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:gXAt4cxheS3wgMbFtc8ACfkHRH09606 rigid:T7MB0QjLpFWfhqYD3ZAvxofpau0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q9P2N6 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-395317|uniprotkb:A1L184|uniprotkb:Q05BU4|uniprotkb:Q6P3X2|uniprotkb:Q6PJH6|uniprotkb:Q86T19|uniprotkb:Q9H0C9|uniprotkb:Q9H8C9|uniprotkb:Q9HAP8|uniprotkb:Q9NWE5|intact:EBI-2560782|intact:EBI-726977|uniprotkb:Q96L64|ensembl:ENSP00000499674|uniprotkb:D3DXH3|uniprotkb:D3DXH4 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:kanl3_human(display_long)|uniprotkb:KANSL3(gene name)|psi-mi:KANSL3(display_short)|uniprotkb:KIAA1310(gene name synonym)|uniprotkb:NSL complex protein NSL3(gene name synonym)|uniprotkb:NSL3(gene name synonym)|uniprotkb:Non-specific lethal 3 homolog(gene name synonym)|uniprotkb:PRTD(gene name synonym)|uniprotkb:SI1(gene name synonym)|uniprotkb:Serum inhibited-related protein(gene name synonym)|uniprotkb:Testis development protein PRTD(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486637|imex:IM-26985-297 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N ensembl:ENSG00000114982(gene)|ensembl:ENST00000666923(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044545"(NSL complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR026555|interpro:IPR029058|mint:Q9P2N6|reactome:R-HSA-3214847|refseq:NP_001108488.1|refseq:XP_005264041.1 - - comment:"author score: 26" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:939a58MqNe7Tnr1HRhS7YpD6s6I9606 rigid:T7MB0QjLpFWfhqYD3ZAvxofpau0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q9BTK6 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-2372223|uniprotkb:A2ICR6|ensembl:ENSP00000326519 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:pagr1_human(display_long)|uniprotkb:PAGR1(gene name)|psi-mi:PAGR1(display_short)|uniprotkb:C16orf53(gene name synonym)|uniprotkb:PA1(gene name synonym)|uniprotkb:PAXIP1-associated protein 1(gene name synonym)|uniprotkb:PTIP-associated protein 1(gene name synonym)|uniprotkb:Glutamate-rich coactivator interacting with SRC1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486637|imex:IM-26985-297 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N refseq:NP_078792.1|ensembl:ENSG00000280789(gene)|ensembl:ENST00000320330(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:1902808"(positive regulation of cell cycle G1/S phase transition)|interpro:IPR028213|mint:Q9BTK6|reactome:R-HSA-5617472 - - comment:"author score: 29" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:9yYPNooDxUEqCQX/n3OUxtRnM9U9606 rigid:T7MB0QjLpFWfhqYD3ZAvxofpau0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q9P2R6 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-948076|uniprotkb:O43393|uniprotkb:O75046|uniprotkb:O75359|uniprotkb:Q5VXL9|uniprotkb:Q6P6B9|uniprotkb:Q9Y2W4|ensembl:ENSP00000338629|ensembl:ENSP00000383700 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:rere_human(display_long)|uniprotkb:Atrophin-1-related protein(gene name synonym)|uniprotkb:Atrophin-1-like protein(gene name synonym)|uniprotkb:RERE(gene name)|psi-mi:RERE(display_short)|uniprotkb:ARG(gene name synonym)|uniprotkb:ARP(gene name synonym)|uniprotkb:ATN1L(gene name synonym)|uniprotkb:KIAA0458(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486637|imex:IM-26985-297 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N refseq:NP_001036146.1|refseq:NP_001036147.1|refseq:NP_036234.3|refseq:XP_005263521.1|refseq:XP_016856847.1|refseq:XP_016856848.1|dip:DIP-47606N|ensembl:ENSG00000142599(gene)|ensembl:ENST00000337907(transcript)|ensembl:ENST00000400908(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0008270"(zinc ion binding)|go:"GO:0021691"(cerebellar Purkinje cell layer maturation)|go:"GO:0021930"(cerebellar granule cell precursor proliferation)|go:"GO:0021942"(radial glia guided migration of Purkinje cell)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0048755"(branching morphogenesis of a nerve)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|interpro:IPR000679(Zinc finger, GATA-type)|interpro:IPR000949(ELM2)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR001025(Bromo adjacent region)|interpro:IPR002951(Atrophin)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017884|mint:Q9P2R6|rcsb pdb:2YQK - - comment:"author score: 31" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:fryo3nxpHdcexG2dqy00t0n4Nlw9606 rigid:T7MB0QjLpFWfhqYD3ZAvxofpau0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q7Z3B3 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-740244|uniprotkb:Q6AW85|uniprotkb:Q8IYH1|uniprotkb:Q9BRH0|uniprotkb:Q9NTE7|uniprotkb:Q9UFT0|uniprotkb:Q9ULF3|uniprotkb:A8K5E4|ensembl:ENSP00000262419|ensembl:ENSP00000387393|ensembl:ENSP00000461484|ensembl:ENSP00000461812|intact:EBI-10178305|uniprotkb:B3KT49|uniprotkb:I3L4J3 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:kanl1_human(display_long)|uniprotkb:KANSL1(gene name)|psi-mi:KANSL1(display_short)|uniprotkb:KIAA1267(gene name synonym)|uniprotkb:MLL1/MLL complex subunit KANSL1(gene name synonym)|uniprotkb:MSL1 homolog 1(gene name synonym)|uniprotkb:MSL1V1(gene name synonym)|uniprotkb:NSL complex protein NSL1(gene name synonym)|uniprotkb:NSL1(gene name synonym)|uniprotkb:Non-specific lethal 1 homolog(gene name synonym)|uniprotkb:CENP-36(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486637|imex:IM-26985-297 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N refseq:NP_001180394.1|refseq:NP_001180395.1|refseq:NP_056258.1|refseq:XP_006721886.1|ensembl:ENSG00000120071(gene)|ensembl:ENST00000262419(transcript)|ensembl:ENST00000432791(transcript)|ensembl:ENST00000572904(transcript)|ensembl:ENST00000574590(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0000776"(kinetochore)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044545"(NSL complex)|go:"GO:0071339"(MLL1 complex)|interpro:IPR026180|interpro:IPR029332|mint:Q7Z3B3|rcsb pdb:4CY1|rcsb pdb:4CY2|reactome:R-HSA-3214847|refseq:XP_006721887.1 - - comment:"author score: 31" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:Co/MKm4PZcwn3BUf6ZKYOqW0VhA9606 rigid:T7MB0QjLpFWfhqYD3ZAvxofpau0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:P51610 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-396176|intact:EBI-2832627|uniprotkb:Q6P4G5|intact:EBI-12037257|intact:EBI-14324845|ensembl:ENSP00000309555|intact:EBI-12980473 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:hcfc1_human(display_long)|uniprotkb:HCFC1(gene name)|psi-mi:HCFC1(display_short)|uniprotkb:HCF1(gene name synonym)|uniprotkb:C1 factor(gene name synonym)|uniprotkb:VP16 accessory protein(gene name synonym)|uniprotkb:VCAF(gene name synonym)|uniprotkb:CFF(gene name synonym)|uniprotkb:HFC1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486637|imex:IM-26985-297 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N refseq:NP_005325.2|refseq:XP_006724879.1|rcsb pdb:6MA1|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|reactome:R-HSA-2151201|reactome:R-HSA-3214847|reactome:R-HSA-5689603|ensembl:ENSG00000172534(gene)|ensembl:ENST00000310441(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019046"(release from viral latency)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR036116|interpro:IPR037854|interpro:IPR043536|mint:P51610|rcsb pdb:4GO6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:5LWV|dip:DIP-32955N - - comment:"author score: 32" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:RzsCRe9l6md3DI87H4ZgdR9oBMI9606 rigid:T7MB0QjLpFWfhqYD3ZAvxofpau0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q9H8E8 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-750907|uniprotkb:Q96GW6|uniprotkb:Q96IH3|uniprotkb:Q9HBF0|uniprotkb:Q9UIY5|uniprotkb:A2A2I5|ensembl:ENSP00000366909|ensembl:ENSP00000392318|ensembl:ENSP00000424752|ensembl:ENSP00000503109|ensembl:ENSP00000503493|ensembl:ENSP00000504050|ensembl:ENSP00000504276 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:csr2b_human(display_long)|uniprotkb:KAT14(gene name)|psi-mi:KAT14(display_short)|uniprotkb:ADA2A-containing complex subunit 2(gene name synonym)|uniprotkb:CRP2-binding partner(gene name synonym)|uniprotkb:CSRP2BP(gene name synonym)|uniprotkb:Lysine acetyltransferase 14(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486637|imex:IM-26985-297 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N refseq:NP_065397.3|ensembl:ENSG00000149474(gene)|ensembl:ENST00000377681(transcript)|ensembl:ENST00000435364(transcript)|ensembl:ENST00000464792(transcript)|ensembl:ENST00000676935(transcript)|ensembl:ENST00000677174(transcript)|ensembl:ENST00000677266(transcript)|ensembl:ENST00000678772(transcript)|go:"GO:0004402"(histone acetyltransferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0030274"(LIM domain binding)|go:"GO:0043966"(histone H3 acetylation)|interpro:IPR000182(GCN5-related N-acetyltransferase)|interpro:IPR016181(Acyl-CoA N-acyltransferase)|interpro:IPR037829|mint:Q9H8E8|reactome:R-HSA-3214847 - - comment:"author score: 34" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:/Udl5yqzzDQ9jsscSVJlzcGd/VI9606 rigid:T7MB0QjLpFWfhqYD3ZAvxofpau0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q96EZ8 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-348259|ensembl:ENSP00000345358|ensembl:ENSP00000448056|uniprotkb:O14742|uniprotkb:O75497|uniprotkb:Q6VN53|uniprotkb:Q7Z372 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:mcrs1_human(display_long)|uniprotkb:MCRS1(gene name)|psi-mi:MCRS1(display_short)|uniprotkb:MSP58(gene name synonym)|uniprotkb:58 kDa microspherule protein(gene name synonym)|uniprotkb:Cell cycle-regulated factor p78(gene name synonym)|uniprotkb:MCRS2(gene name synonym)|uniprotkb:INO80Q(gene name synonym)|uniprotkb:INO80 complex subunit J(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486637|imex:IM-26985-297 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N ensembl:ENSG00000187778(gene)|ensembl:ENST00000343810(transcript)|ensembl:ENST00000550165(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005844"(polysome)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010521"(telomerase inhibitor activity)|go:"GO:0030425"(dendrite)|go:"GO:0031011"(Ino80 complex)|go:"GO:0034046"("poly(G) binding")|go:"GO:0043204"(perikaryon)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0044545"(NSL complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR025999|interpro:IPR037912|mint:Q96EZ8|reactome:R-HSA-3214847|go:"GO:0043984"(histone H4-K16 acetylation)|reactome:R-HSA-5689603|reactome:R-HSA-5696394|refseq:NP_001012300.1|refseq:NP_006328.2|refseq:NP_001265270.1|refseq:XP_005268629.1|refseq:XP_016874178.1|refseq:XP_016874179.1 - - comment:"author score: 34" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:b6u2XbKLMDkL1zbLTPBjq9J23Zs9606 rigid:T7MB0QjLpFWfhqYD3ZAvxofpau0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q14686 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-78670|uniprotkb:A6NLF1|uniprotkb:Q9NTZ9|uniprotkb:Q9UH74|uniprotkb:Q9UK86|ensembl:ENSP00000351894|ensembl:ENSP00000363929|uniprotkb:B2RMN5|uniprotkb:E1P5P7 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:ncoa6_human(display_long)|uniprotkb:NCOA6(gene name)|psi-mi:NCOA6(display_short)|uniprotkb:KIAA0181(gene name synonym)|uniprotkb:RAP250(gene name synonym)|uniprotkb:Amplified in breast cancer protein 3(gene name synonym)|uniprotkb:Cancer-amplified transcriptional coactivator ASC-2(gene name synonym)|uniprotkb:Activating signal cointegrator 2(gene name synonym)|uniprotkb:Peroxisome proliferator-activated receptor-interacting protein(gene name synonym)|uniprotkb:Nuclear receptor-activating protein, 250 kDa(gene name synonym)|uniprotkb:Nuclear receptor coactivator RAP250(gene name synonym)|uniprotkb:Thyroid hormone receptor-binding protein(gene name synonym)|uniprotkb:AIB3(gene name synonym)|uniprotkb:TRBP(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486637|imex:IM-26985-297 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N refseq:NP_001229468.1|refseq:NP_054790.2|ensembl:ENSG00000198646(gene)|ensembl:ENST00000359003(transcript)|ensembl:ENST00000374796(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005829"(cytosol)|go:"GO:0006352"(DNA-templated transcription, initiation)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007420"(brain development)|go:"GO:0007507"(heart development)|go:"GO:0009725"(response to hormone)|go:"GO:0019899"(enzyme binding)|go:"GO:0030099"(myeloid cell differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046965"(retinoid X receptor binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0051427"(hormone receptor binding)|interpro:IPR026638|interpro:IPR032715|mint:Q14686|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-381340|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-5617472|reactome:R-HSA-9707564|reactome:R-HSA-9707616|ensembl:ENSP00000351894|ensembl:ENSP00000363929|refseq:NP_001305169.1|dip:DIP-30934N - - comment:"author score: 35" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:0PZz93t/oHYDVeiX+8NqjSlpNRo9606 rigid:T7MB0QjLpFWfhqYD3ZAvxofpau0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q9H9L4 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-2560840|uniprotkb:Q8N3B5|uniprotkb:Q9NX51|uniprotkb:Q96CV0|ensembl:ENSP00000415436 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:kanl2_human(display_long)|uniprotkb:KANSL2(gene name)|psi-mi:KANSL2(display_short)|uniprotkb:C12orf41(gene name synonym)|uniprotkb:NSL complex protein NSL2(gene name synonym)|uniprotkb:NSL2(gene name synonym)|uniprotkb:Non-specific lethal 2 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486637|imex:IM-26985-297 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N refseq:NP_060292.3|ensembl:ENSG00000139620(gene)|ensembl:ENST00000420613(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044545"(NSL complex)|interpro:IPR025927|interpro:IPR026316|mint:Q9H9L4|rcsb pdb:4CY2|reactome:R-HSA-3214847 - - comment:"author score: 37" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:ymOXqnaeH6HuGcHPg4R2XVmWAz89606 rigid:T7MB0QjLpFWfhqYD3ZAvxofpau0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q6ZW49 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-743225|ensembl:ENSP00000380376|ensembl:ENSP00000384048|uniprotkb:O15404|uniprotkb:Q6N099|uniprotkb:Q6ZWH9|uniprotkb:Q7Z315|uniprotkb:Q86UN0|uniprotkb:Q8N4P9|uniprotkb:Q96HP2 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:paxi1_human(display_long)|uniprotkb:PAX transactivation activation domain-interacting protein(gene name synonym)|uniprotkb:PAXIP1(gene name)|psi-mi:PAXIP1(display_short)|uniprotkb:PAXIP1L(gene name synonym)|uniprotkb:PTIP(gene name synonym)|uniprotkb:CAGF28(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486637|imex:IM-26985-297 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N go:"GO:0006310"(DNA recombination)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0035066"(positive regulation of histone acetylation)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045830"(positive regulation of isotype switching)|go:"GO:0048304"(positive regulation of isotype switching to IgG isotypes)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0060261"(positive regulation of transcription initiation from RNA polymerase II promoter)|go:"GO:0060612"(adipose tissue development)|go:"GO:0060717"(chorion development)|go:"GO:1902749"(regulation of cell cycle G2/M phase transition)|go:"GO:2001022"(positive regulation of response to DNA damage stimulus)|interpro:IPR001357(BRCT)|interpro:IPR036420|interpro:IPR037886|mint:Q6ZW49|rcsb pdb:3SQD|reactome:R-HSA-5617472|reactome:R-HSA-5693571|refseq:NP_031375.3|ensembl:ENSG00000157212(gene)|ensembl:ENST00000397192(transcript)|ensembl:ENST00000404141(transcript)|go:"GO:0000416"(positive regulation of histone H3-K36 methylation)|go:"GO:0001570"(vasculogenesis)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006281"(DNA repair)|refseq:XP_005249596.1|refseq:XP_016867370.1|dip:DIP-41786N - - comment:"author score: 39" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:djzoPtMxXMP9LBvpzVNBcq04QEY9606 rigid:T7MB0QjLpFWfhqYD3ZAvxofpau0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q8IYH5 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-2795524|uniprotkb:B7WPC6|uniprotkb:Q6N004|uniprotkb:Q6N070|uniprotkb:Q8IYP0|uniprotkb:Q8IYR1|uniprotkb:Q8TEK4|uniprotkb:Q9Y4U0|ensembl:ENSP00000359837 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:zzz3_human(display_long)|uniprotkb:ZZZ3(gene name)|psi-mi:ZZZ3(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486637|imex:IM-26985-297 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N refseq:NP_001295166.1|refseq:NP_056349.1|refseq:XP_016856459.1|refseq:XP_005270782.1|refseq:XP_005270783.1|refseq:XP_005270784.1|refseq:XP_005270786.1|ensembl:ENSG00000036549(gene)|ensembl:ENST00000370801(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0008270"(zinc ion binding)|go:"GO:0043967"(histone H4 acetylation)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001005(SANT, DNA-binding)|interpro:IPR009057(Homeodomain-like)|interpro:IPR017930|interpro:IPR037830|interpro:IPR041981|interpro:IPR043145|rcsb pdb:2FC7|rcsb pdb:2YUM|rcsb pdb:6E83|rcsb pdb:6E86|reactome:R-HSA-3214847|mint:Q8IYH5|dip:DIP-47289N - - comment:"author score: 40" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:F8aEW+XePZMAIrIAIDMEnBXdSBo9606 rigid:T7MB0QjLpFWfhqYD3ZAvxofpau0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q9Y5Z7 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-592728|uniprotkb:B2R8Q5|uniprotkb:C0H5X3|ensembl:ENSP00000229330 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:hcfc2_human(display_long)|uniprotkb:C2 factor(gene name synonym)|uniprotkb:HCFC2(gene name)|psi-mi:HCFC2(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486637|imex:IM-26985-297 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N refseq:NP_037452.1|ensembl:ENSG00000111727(gene)|ensembl:ENST00000229330(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016032"(viral process)|go:"GO:0016604"(nuclear body)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0071339"(MLL1 complex)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR011043(Galactose oxidase/kelch, beta-propeller)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR036116|interpro:IPR037932|interpro:IPR043536|mint:Q9Y5Z7 - - comment:"author score: 41" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:ytE7Aid9JO9RWsRpJPpBbylLRXo9606 rigid:T7MB0QjLpFWfhqYD3ZAvxofpau0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q9NS73 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-741953|uniprotkb:Q86TZ2|uniprotkb:Q96AS5|uniprotkb:Q9BS93|uniprotkb:Q9NZE1|ensembl:ENSP00000399718 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:mbip1_human(display_long)|uniprotkb:MAPK upstream kinase-binding inhibitory protein(gene name synonym)|uniprotkb:MBIP(gene name)|psi-mi:MBIP(display_short)|uniprotkb:BM-015(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486637|imex:IM-26985-297 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N refseq:NP_001138363.1|refseq:NP_057670.2|ensembl:ENSG00000151332(gene)|ensembl:ENST00000416007(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042802"(identical protein binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0046330"(positive regulation of JNK cascade)|interpro:IPR026062|mint:Q9NS73|reactome:R-HSA-3214847|go:"GO:0005654"(nucleoplasm)|refseq:NP_001295039.1 - - comment:"author score: 42" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:PjaEuab6wwOyGImpNYFZfQ+TUvU9606 rigid:T7MB0QjLpFWfhqYD3ZAvxofpau0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:O75461 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-749694|uniprotkb:O60544|uniprotkb:Q53QY9|uniprotkb:Q7Z2H6|uniprotkb:A8K2Z8|uniprotkb:G5E936|uniprotkb:Q6Q9Z6|ensembl:ENSP00000370936 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:e2f6_human(display_long)|uniprotkb:E2F6(gene name)|psi-mi:E2F6(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486637|imex:IM-26985-297 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N refseq:NP_001265204.1|refseq:NP_001265205.1|refseq:NP_001265206.1|refseq:NP_001265207.1|refseq:NP_937987.2|dip:DIP-41699N|ensembl:ENSG00000169016(gene)|ensembl:ENST00000381525(transcript)|go:"GO:0000083"(regulation of transcription involved in G1/S transition of mitotic cell cycle)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|interpro:IPR003316("Transcription factor E2F/dimerisation partner (TDP)")|interpro:IPR015633(E2F Family)|interpro:IPR015635(Transcription Factor E2F6)|interpro:IPR036388|interpro:IPR036390|interpro:IPR037241|mint:O75461|reactome:R-HSA-69205|reactome:R-HSA-8953750|interpro:IPR032198 - - comment:"author score: 43" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:HZpQSfeASNNMLz4NCYOp6T0yXTk9606 rigid:T7MB0QjLpFWfhqYD3ZAvxofpau0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q8IWI9 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-2815196|uniprotkb:E7ENI0|uniprotkb:F5H7K2|uniprotkb:Q9H9N7|uniprotkb:Q9H8R3|uniprotkb:Q9Y4E9|uniprotkb:Q9UG69|intact:EBI-11143500|intact:EBI-10969960|ensembl:ENSP00000219905|uniprotkb:B9EGR5 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:mgap_human(display_long)|uniprotkb:MGA(gene name)|psi-mi:MGA(display_short)|uniprotkb:KIAA0518(gene name synonym)|uniprotkb:MAD5(gene name synonym)|uniprotkb:MAX dimerization protein 5(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486637|imex:IM-26985-297 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N refseq:NP_001074010.2|ensembl:ENSP00000219905|ensembl:ENST00000566586|ensembl:ENSP00000456141|ensembl:ENSG00000174197(gene)|ensembl:ENST00000219905(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001708"(cell fate specification)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001699(Transcription factor, T-box)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR011598(Helix-loop-helix DNA-binding)|interpro:IPR018186|interpro:IPR032060|interpro:IPR036638|interpro:IPR036960|interpro:IPR037935|mint:Q8IWI9|reactome:R-HSA-8953750|refseq:NP_001157745.1|dip:DIP-57615N - - comment:"author score: 49" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:P4lo9EteCvikQQk5kyVkcobitLU9606 rigid:T7MB0QjLpFWfhqYD3ZAvxofpau0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q9ULM3 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-2795509|uniprotkb:A7E2B9|uniprotkb:Q641P6|uniprotkb:Q9NW96|uniprotkb:D3DNS9|ensembl:ENSP00000306983 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:yets2_human(display_long)|uniprotkb:YEATS2(gene name)|psi-mi:YEATS2(display_short)|uniprotkb:KIAA1197(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486637|imex:IM-26985-297 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N refseq:NP_060493.3|refseq:XP_016862298.1|refseq:XP_016862299.1|reactome:R-HSA-3214847|rcsb pdb:6LSD|ensembl:ENST00000305135(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0072686"(mitotic spindle)|go:"GO:0140030"(modification-dependent protein binding)|interpro:IPR005033(YEATS)|interpro:IPR038704|mint:Q9ULM3|rcsb pdb:5IQL|ensembl:ENSG00000163872(gene)|rcsb pdb:5XNV - - comment:"author score: 50" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:dbdCDssB6o5aHKaRdnvITi8b/v09606 rigid:T7MB0QjLpFWfhqYD3ZAvxofpau0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q8NEZ4 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-1042997|uniprotkb:Q8NC02|uniprotkb:Q8NDF6|uniprotkb:Q9H9P4|uniprotkb:Q9NR13|uniprotkb:Q9P222|uniprotkb:Q9UDR7|ensembl:ENSP00000262189 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:kmt2c_human(display_long)|uniprotkb:KMT2C(gene name)|psi-mi:KMT2C(display_short)|uniprotkb:HALR(gene name synonym)|uniprotkb:Homologous to ALR protein(gene name synonym)|uniprotkb:KIAA1506(gene name synonym)|uniprotkb:MLL3(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486637|imex:IM-26985-297 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N ensembl:ENSG00000055609(gene)|ensembl:ENST00000262189(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016746"(acyltransferase activity)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042393"(histone binding)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0097692"(histone H3-K4 monomethylation)|interpro:IPR000637(HMG-I and HMG-Y, DNA-binding)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|go:"GO:0005634"(nucleus)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036910|interpro:IPR037877|interpro:IPR041967|interpro:IPR041968|mint:Q8NEZ4|rcsb pdb:2YSM|rcsb pdb:2YUK|rcsb pdb:3UVL|rcsb pdb:4ERY|rcsb pdb:5F59|rcsb pdb:5F6K|rcsb pdb:6KIW|rcsb pdb:6MLC|reactome:R-HSA-3214841|reactome:R-HSA-5617472|reactome:R-HSA-8936459|refseq:NP_733751.2|ensembl:ENSP00000262189|ensembl:ENST00000682283|ensembl:ENSP00000507485|dip:DIP-48649N - - comment:"author score: 51" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:NZg8HgfbohMT8EEgAdAgWR1AjSo9606 rigid:T7MB0QjLpFWfhqYD3ZAvxofpau0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q03164 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-591370|ensembl:ENSP00000374157|uniprotkb:Q13743|uniprotkb:Q13744|uniprotkb:Q14845|uniprotkb:Q16364|uniprotkb:Q6UBD1|uniprotkb:Q9UMA3|intact:EBI-2614650|uniprotkb:Q59FF2|uniprotkb:Q9UD94|uniprotkb:E9PQG7|uniprotkb:Q9HBJ3 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:kmt2a_human(display_long)|uniprotkb:KMT2A(gene name)|psi-mi:KMT2A(display_short)|uniprotkb:ALL-1(gene name synonym)|uniprotkb:ALL1(gene name synonym)|uniprotkb:CXXC-type zinc finger protein 7(gene name synonym)|uniprotkb:CXXC7(gene name synonym)|uniprotkb:HRX(gene name synonym)|uniprotkb:HTRX(gene name synonym)|uniprotkb:MLL(gene name synonym)|uniprotkb:MLL1(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 1(gene name synonym)|uniprotkb:TRX1(gene name synonym)|uniprotkb:Trithorax-like protein(gene name synonym)|uniprotkb:Zinc finger protein HRX(gene name synonym)|uniprotkb:Cysteine methyltransferase KMT2A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486637|imex:IM-26985-297 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N go:"GO:2000615"(regulation of histone H3-K9 acetylation)|interpro:IPR001214(SET)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016569(Methyltransferase, trithorax)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036427|interpro:IPR037927|interpro:IPR041958|interpro:IPR042023|interpro:IPR042025|interpro:IPR044133|mint:Q03164|rcsb pdb:2AGH|rcsb pdb:2J2S|rcsb pdb:2JYI|rcsb pdb:2KKF|rcsb pdb:2KU7|rcsb pdb:2KYU|rcsb pdb:2LXS|rcsb pdb:2LXT|rcsb pdb:2MSR|rcsb pdb:2MTN|rcsb pdb:2W5Y|ensembl:ENSG00000118058(gene)|ensembl:ENST00000389506(transcript)|go:"GO:0003680"(minor groove of adenine-thymine-rich DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0008270"(zinc ion binding)|go:"GO:0032411"(positive regulation of transporter activity)|go:"GO:0032922"(circadian regulation of gene expression)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0035162"(embryonic hemopoiesis)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071440"(regulation of histone H3-K14 acetylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:0106363"(protein-cysteine methyltransferase activity)|go:"GO:1905642"(negative regulation of DNA methylation)|refseq:NP_001184033.1|refseq:NP_005924.2|ensembl:ENSP00000374157|ensembl:ENST00000534358|ensembl:ENSP00000436786|ensembl:ENST00000649699|ensembl:ENSP00000496927|dip:DIP-29221N|rcsb pdb:2W5Z|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3LQH|rcsb pdb:3LQI|rcsb pdb:3LQJ|rcsb pdb:3P4F|rcsb pdb:3U85|rcsb pdb:3U88|rcsb pdb:4ESG|rcsb pdb:4GQ6|rcsb pdb:4NW3|rcsb pdb:5F5E|rcsb pdb:5F6L|rcsb pdb:5SVH|rcsb pdb:6EMQ|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U9K|rcsb pdb:6U9M|rcsb pdb:6U9N|rcsb pdb:6U9R|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|reactome:R-HSA-3214841|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9616222 - - comment:"author score: 54" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:r9J9pjnLZI7GCBSHYqnmzjv9WvM9606 rigid:T7MB0QjLpFWfhqYD3ZAvxofpau0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q9UMN6 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-765774|uniprotkb:O15022|uniprotkb:O95836|uniprotkb:Q96GP2|uniprotkb:Q96IP3|uniprotkb:Q9UK25|uniprotkb:Q9Y668|uniprotkb:Q9Y669|ensembl:ENSP00000398837 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:kmt2b_human(display_long)|uniprotkb:KMT2B(gene name)|psi-mi:KMT2B(display_short)|uniprotkb:HRX2(gene name synonym)|uniprotkb:KIAA0304(gene name synonym)|uniprotkb:MLL2(gene name synonym)|uniprotkb:MLL4(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 4(gene name synonym)|uniprotkb:TRX2(gene name synonym)|uniprotkb:Trithorax homolog 2(gene name synonym)|uniprotkb:WBP7(gene name synonym)|uniprotkb:WW domain-binding protein 7(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486637|imex:IM-26985-297 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N ensembl:ENSP00000398837|dip:DIP-34598N|ensembl:ENSG00000272333(gene)|ensembl:ENST00000420124(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0008270"(zinc ion binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|interpro:IPR001214(SET)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR016569(Methyltransferase, trithorax)|interpro:IPR019787|interpro:IPR034732|interpro:IPR036427|interpro:IPR041959|mint:Q9UMN6|rcsb pdb:3UVM|rcsb pdb:4ERZ|rcsb pdb:4PZI|rcsb pdb:7BRE|reactome:R-HSA-3214841|reactome:R-HSA-8936459 - - comment:"author score: 54" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:1Im1Dqkyg85ZGqrxLaK4wyMVGNY9606 rigid:T7MB0QjLpFWfhqYD3ZAvxofpau0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:O15047 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-540779|uniprotkb:A6NP62|uniprotkb:Q6PIF3|uniprotkb:Q8TAJ6|intact:EBI-28969638|ensembl:ENSP00000262519|ensembl:ENSP00000507683 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:set1a_human(display_long)|uniprotkb:KMT2F(gene name synonym)|uniprotkb:SET domain-containing protein 1A(gene name synonym)|uniprotkb:Set1/Ash2 histone methyltransferase complex subunit SET1(gene name synonym)|uniprotkb:Lysine N-methyltransferase 2F(gene name synonym)|uniprotkb:SETD1A(gene name)|psi-mi:SETD1A(display_short)|uniprotkb:KIAA0339(gene name synonym)|uniprotkb:SET1(gene name synonym)|uniprotkb:SET1A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486637|imex:IM-26985-297 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N refseq:NP_055527.1|refseq:XP_006721169.1|ensembl:ENSP00000262519|ensembl:ENSP00000507683|reactome:R-HSA-8936459|reactome:R-HSA-3214841|ensembl:ENSG00000099381(gene)|ensembl:ENST00000262519(transcript)|ensembl:ENST00000684162(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007420"(brain development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|go:"GO:1902275"(regulation of chromatin organization)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR001214(SET)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR024657|interpro:IPR034467|interpro:IPR035979|interpro:IPR037841|interpro:IPR044570|mint:O15047|go:"GO:0048188"(Set1C/COMPASS complex)|rcsb pdb:3S8S|rcsb pdb:3UVN|rcsb pdb:4EWR|refseq:XP_005255780.1|refseq:XP_016879398.1|dip:DIP-33494N - - comment:"author score: 55" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:nx0uWEVFas1w2NmuG73lCObAULE9606 rigid:T7MB0QjLpFWfhqYD3ZAvxofpau0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q9BYE7 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-1048026|uniprotkb:Q5SYD1|uniprotkb:Q5SYD6|uniprotkb:Q96ID9|uniprotkb:Q96SJ1|uniprotkb:A8K3R4|ensembl:ENSP00000358862 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:pcgf6_human(display_long)|uniprotkb:RING finger protein 134(gene name synonym)|uniprotkb:Mel18 and Bmi1-like RING finger(gene name synonym)|uniprotkb:PCGF6(gene name)|psi-mi:PCGF6(display_short)|uniprotkb:MBLR(gene name synonym)|uniprotkb:RNF134(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486637|imex:IM-26985-297 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N refseq:NP_001011663.1|refseq:NP_115530.2|ensembl:ENSG00000156374(gene)|ensembl:ENST00000369847(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0031519"(PcG protein complex)|go:"GO:0035102"(PRC1 complex)|go:"GO:0036353"(histone H2A-K119 monoubiquitination)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR029071|interpro:IPR038037|mint:Q9BYE7|rcsb pdb:2DJB|reactome:R-HSA-8953750|dip:DIP-50946N - - comment:"author score: 55" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:BApgBDvXZOaRMKZWK0oa4IHwVjM9606 rigid:T7MB0QjLpFWfhqYD3ZAvxofpau0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:O14686 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-996065|uniprotkb:O14687|intact:EBI-28986759|ensembl:ENSP00000301067 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:kmt2d_human(display_long)|uniprotkb:KMT2D(gene name)|psi-mi:KMT2D(display_short)|uniprotkb:ALL1-related protein(gene name synonym)|uniprotkb:ALR(gene name synonym)|uniprotkb:MLL2(gene name synonym)|uniprotkb:MLL4(gene name synonym)|uniprotkb:Myeloid/lymphoid or mixed-lineage leukemia protein 2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486637|imex:IM-26985-297 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N refseq:NP_003473.3|refseq:XP_006719677.1|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0042800"("histone methyltransferase activity (H3-K4 specific)")|go:"GO:0043627"(response to estrogen)|go:"GO:0044648"(histone H3-K4 dimethylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048477"(oogenesis)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0080182"(histone H3-K4 trimethylation)|go:"GO:0097692"(histone H3-K4 monomethylation)|go:"GO:1904837"(beta-catenin-TCF complex assembly)|interpro:IPR001214(SET)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003616(Post-SET zinc-binding region)|interpro:IPR003888(FY-rich, N-terminal)|interpro:IPR003889(FY-rich, C-terminal)|interpro:IPR009071(High mobility group box, HMG)|ensembl:ENSG00000167548(gene)|ensembl:ENST00000301067(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001555"(oocyte growth)|go:"GO:0003677"(DNA binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006342"|interpro:IPR036910|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR037890|interpro:IPR041961|interpro:IPR041964|mint:O14686|rcsb pdb:3UVK|rcsb pdb:4ERQ|rcsb pdb:4Z4P|rcsb pdb:6O7G|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019787|interpro:IPR034732|ensembl:ENSP00000301067|refseq:XP_005269219.1|dip:DIP-37875N - - comment:"author score: 57" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:eaCGHR6OqxzL66VYfOrzBWJApHY9606 rigid:T7MB0QjLpFWfhqYD3ZAvxofpau0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q9C005 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-744973|uniprotkb:D6W578|ensembl:ENSP00000295066|ensembl:ENSP00000345837 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:dpy30_human(display_long)|uniprotkb:DPY30(gene name)|psi-mi:DPY30(display_short)|uniprotkb:Dpy-30-like protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486637|imex:IM-26985-297 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N refseq:NP_115963.1|ensembl:ENSG00000162961(gene)|ensembl:ENST00000295066(transcript)|ensembl:ENST00000342166(transcript)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006348"|go:"GO:0016197"(endosomal transport)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR007858(Dpy-30)|interpro:IPR037856|mint:Q9C005|rcsb pdb:3G36|rcsb pdb:4RIQ|rcsb pdb:4RT4|rcsb pdb:4RTA|rcsb pdb:6E2H|rcsb pdb:6PWV|reactome:R-HSA-3214841|reactome:R-HSA-8936459|refseq:NP_001308138.1|dip:DIP-34476N - - comment:"author score: 77" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:yC9NJhTfEIT+YyfWRSJLGbRsQkc9606 rigid:T7MB0QjLpFWfhqYD3ZAvxofpau0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q9P0U4 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-949911|ensembl:ENSP00000285106|uniprotkb:Q8N2W4|uniprotkb:Q96BC8|uniprotkb:Q9P2V7|uniprotkb:B2RC03 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:cxxc1_human(display_long)|uniprotkb:CFP1(gene name synonym)|uniprotkb:PHD finger and CXXC domain-containing protein 1(gene name synonym)|uniprotkb:CXXC1(gene name)|psi-mi:CXXC1(display_short)|uniprotkb:CGBP(gene name synonym)|uniprotkb:PCCX1(gene name synonym)|uniprotkb:PHF18(gene name synonym)|uniprotkb:CpG-binding protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486637|imex:IM-26985-297 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N ensembl:ENSG00000154832(gene)|ensembl:ENST00000285106(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016607"(nuclear speck)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0045322"(unmethylated CpG binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002857(Zinc finger, CXXC-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|reactome:R-HSA-381038|interpro:IPR022056|interpro:IPR037869|mint:Q9P0U4|rcsb pdb:3QMB|rcsb pdb:3QMC|rcsb pdb:3QMD|rcsb pdb:3QMG|rcsb pdb:3QMH|rcsb pdb:3QMI|refseq:NP_001095124.1|refseq:NP_055408.2|refseq:XP_011524242.1|refseq:XP_016881207.1|dip:DIP-50001N - - comment:"author score: 89" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:nWwPX7OlafdCMD8Qg+hETjNkKgY9606 rigid:T7MB0QjLpFWfhqYD3ZAvxofpau0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P61964 uniprotkb:Q15291 intact:EBI-540834|uniprotkb:Q91VA5|uniprotkb:Q9NWX7|uniprotkb:Q9UGP9|intact:EBI-28992503|ensembl:ENSP00000351446|intact:EBI-5774097 intact:EBI-592823|uniprotkb:A8K272|uniprotkb:Q7Z6D8|uniprotkb:Q8NDZ7|ensembl:ENSP00000264515 psi-mi:wdr5_human(display_long)|uniprotkb:BMP2-induced 3-kb gene protein(gene name synonym)|uniprotkb:WDR5(gene name)|psi-mi:WDR5(display_short)|uniprotkb:BIG3(gene name synonym) psi-mi:rbbp5_human(display_long)|uniprotkb:Retinoblastoma-binding protein RBQ-3(gene name synonym)|uniprotkb:RBBP5(gene name)|psi-mi:RBBP5(display_short)|uniprotkb:RBQ3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25486637|imex:IM-26985-297 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_060058.1|refseq:NP_438172.1|rcsb pdb:4GMB|rcsb pdb:4IA9|rcsb pdb:4O45|rcsb pdb:4QL1|rcsb pdb:4Y7R|rcsb pdb:5EAL|rcsb pdb:5EAM|rcsb pdb:5EAP|rcsb pdb:5EAR|rcsb pdb:5M23|rcsb pdb:5M25|rcsb pdb:5SXM|rcsb pdb:5VFC|rcsb pdb:6BYN|rcsb pdb:6D9X|rcsb pdb:6DAI|rcsb pdb:6DAK|rcsb pdb:6DAR|rcsb pdb:6DAS|rcsb pdb:6DY7|rcsb pdb:6DYA|rcsb pdb:6E1Y|rcsb pdb:6E1Z|rcsb pdb:6E22|rcsb pdb:6E23|rcsb pdb:6IAM|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6OFZ|rcsb pdb:6OI0|rcsb pdb:6OI1|rcsb pdb:6OI2|rcsb pdb:6OI3|rcsb pdb:6PG3|rcsb pdb:6PG4|rcsb pdb:6PG5|rcsb pdb:6PG6|rcsb pdb:6PG7|rcsb pdb:6PG8|rcsb pdb:6PG9|rcsb pdb:6PGA|rcsb pdb:6PGB|rcsb pdb:6PGC|rcsb pdb:6PGD|rcsb pdb:6PGE|rcsb pdb:6PGF|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6U5M|rcsb pdb:6U5Y|rcsb pdb:6U6W|rcsb pdb:6U80|rcsb pdb:6U8B|rcsb pdb:6U8L|rcsb pdb:6U8O|rcsb pdb:6UCS|rcsb pdb:6UFX|rcsb pdb:6UHY|rcsb pdb:6UHZ|rcsb pdb:6UIF|rcsb pdb:6UIK|rcsb pdb:6UJ4|rcsb pdb:6UJH|rcsb pdb:6UJJ|rcsb pdb:6UJL|rcsb pdb:6UOZ|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:6WJQ|rcsb pdb:7DNO|reactome:R-HSA-3214841|reactome:R-HSA-3214847|reactome:R-HSA-3214858|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664|ensembl:ENSG00000196363(gene)|ensembl:ENST00000358625(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0001501"(skeletal system development)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005671"(obsolete Ada2/Gcn5/Ada3 transcription activator complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042393"(histone binding)|go:"GO:0043966"(histone H3 acetylation)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0045722"(positive regulation of gluconeogenesis)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|mint:P61964|rcsb pdb:2CNX|rcsb pdb:2CO0|rcsb pdb:2G99|rcsb pdb:2G9A|rcsb pdb:2GNQ|rcsb pdb:2H13|rcsb pdb:2H14|rcsb pdb:2H68|rcsb pdb:2H6K|rcsb pdb:2H6N|rcsb pdb:2H6Q|rcsb pdb:2H9L|rcsb pdb:2H9M|rcsb pdb:2H9N|rcsb pdb:2H9P|rcsb pdb:2O9K|rcsb pdb:3EG6|rcsb pdb:3EMH|rcsb pdb:3MXX|rcsb pdb:3N0D|rcsb pdb:3N0E|rcsb pdb:3P4F|rcsb pdb:3PSL|rcsb pdb:3SMR|rcsb pdb:3UR4|rcsb pdb:3UVK|rcsb pdb:3UVL|rcsb pdb:3UVM|rcsb pdb:3UVN|rcsb pdb:3UVO|rcsb pdb:4A7J|rcsb pdb:4CY1|rcsb pdb:4CY2|rcsb pdb:4ERQ|rcsb pdb:4ERY|rcsb pdb:4ERZ|rcsb pdb:4ES0|rcsb pdb:4ESG|rcsb pdb:4EWR|rcsb pdb:4GM3|rcsb pdb:4GM8|rcsb pdb:4GM9|ensembl:ENSP00000351446|refseq:XP_005272220.1|dip:DIP-29223N refseq:NP_001180201.1|refseq:NP_001180202.1|refseq:NP_005048.2|dip:DIP-29224N|ensembl:ENSG00000117222(gene)|ensembl:ENST00000264515(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0043627"(response to estrogen)|go:"GO:0044666"(MLL3/4 complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0071339"(MLL1 complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR037850|mint:Q15291|rcsb pdb:3P4F|rcsb pdb:4X8N|rcsb pdb:4X8P|rcsb pdb:5F6K|rcsb pdb:5F6L|rcsb pdb:6KIU|rcsb pdb:6KIV|rcsb pdb:6KIW|rcsb pdb:6KIX|rcsb pdb:6KIZ|rcsb pdb:6KM7|rcsb pdb:6PWV|rcsb pdb:6PWW|rcsb pdb:6PWX|rcsb pdb:6W5I|rcsb pdb:6W5M|rcsb pdb:6W5N|rcsb pdb:7BRE|reactome:R-HSA-201722|reactome:R-HSA-3214841|reactome:R-HSA-3769402|reactome:R-HSA-5617472|reactome:R-HSA-8936459|reactome:R-HSA-8951664 - - comment:"author score: 141" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:MNq7yCtkHPFRGiq1fP5TAwcGUAU9606 rogid:Zl8yHcbL1C6StHPyD+875Ccy6gk9606 rigid:T7MB0QjLpFWfhqYD3ZAvxofpau0 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P25490 uniprotkb:Q53TQ3 intact:EBI-765538|uniprotkb:Q14935|ensembl:ENSP00000262238 intact:EBI-769603|uniprotkb:Q6PJU1|uniprotkb:Q6PKA1|uniprotkb:Q9NXD5|uniprotkb:Q6PJC6|uniprotkb:B3KU68|uniprotkb:B9EG77|ensembl:ENSP00000384198|ensembl:ENSP00000490850|intact:EBI-21657516 psi-mi:tyy1_human(display_long)|uniprotkb:Yin and yang 1(gene name synonym)|uniprotkb:Delta transcription factor(gene name synonym)|uniprotkb:NF-E1(gene name synonym)|uniprotkb:YY1(gene name)|psi-mi:YY1(display_short)|uniprotkb:INO80S(gene name synonym)|uniprotkb:INO80 complex subunit S(gene name synonym) psi-mi:in80d_human(display_long)|uniprotkb:INO80D(gene name)|psi-mi:INO80D(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487000|imex:IM-26985-379 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003394.1|dip:DIP-150N|ensembl:ENSG00000100811(gene)|rcsb pdb:1UBD|rcsb pdb:1ZNM|rcsb pdb:4C5I|reactome:R-HSA-5617472|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8866910|reactome:R-HSA-9018519|ensembl:ENST00000262238(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006403"(RNA localization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010225"(response to UV-C)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034696"(response to prostaglandin F)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048468"(cell development)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0051276"(chromosome organization)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017114(Transcription factor yin and yang)|interpro:IPR036236|mint:P25490 refseq:XP_011509677.1|refseq:XP_011509678.1|ensembl:ENSP00000384198|ensembl:ENSP00000490850|ensembl:ENSG00000114933(gene)|ensembl:ENSG00000283510(gene)|ensembl:ENST00000403263(transcript)|ensembl:ENST00000636453(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|interpro:IPR025927|mint:Q53TQ3|reactome:R-HSA-5689603|reactome:R-HSA-5696394|refseq:NP_060229.3|refseq:XP_011509672.1|refseq:XP_011509673.1|refseq:XP_011509675.1 - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:OncFlxfcbNZGN68Sk39CRh9oQHc9606 rogid:uAVyU39fDAWdiToA8FknicX0g1E9606 rigid:6bMEfQoBNWzM+oI12nh9FRkmv0Q false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P25490 uniprotkb:Q96EZ8 intact:EBI-765538|uniprotkb:Q14935|ensembl:ENSP00000262238 intact:EBI-348259|ensembl:ENSP00000345358|ensembl:ENSP00000448056|uniprotkb:O14742|uniprotkb:O75497|uniprotkb:Q6VN53|uniprotkb:Q7Z372 psi-mi:tyy1_human(display_long)|uniprotkb:Yin and yang 1(gene name synonym)|uniprotkb:Delta transcription factor(gene name synonym)|uniprotkb:NF-E1(gene name synonym)|uniprotkb:YY1(gene name)|psi-mi:YY1(display_short)|uniprotkb:INO80S(gene name synonym)|uniprotkb:INO80 complex subunit S(gene name synonym) psi-mi:mcrs1_human(display_long)|uniprotkb:MCRS1(gene name)|psi-mi:MCRS1(display_short)|uniprotkb:MSP58(gene name synonym)|uniprotkb:58 kDa microspherule protein(gene name synonym)|uniprotkb:Cell cycle-regulated factor p78(gene name synonym)|uniprotkb:MCRS2(gene name synonym)|uniprotkb:INO80Q(gene name synonym)|uniprotkb:INO80 complex subunit J(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487000|imex:IM-26985-379 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003394.1|dip:DIP-150N|ensembl:ENSG00000100811(gene)|rcsb pdb:1UBD|rcsb pdb:1ZNM|rcsb pdb:4C5I|reactome:R-HSA-5617472|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8866910|reactome:R-HSA-9018519|ensembl:ENST00000262238(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006403"(RNA localization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010225"(response to UV-C)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034696"(response to prostaglandin F)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048468"(cell development)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0051276"(chromosome organization)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017114(Transcription factor yin and yang)|interpro:IPR036236|mint:P25490 ensembl:ENSG00000187778(gene)|ensembl:ENST00000343810(transcript)|ensembl:ENST00000550165(transcript)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005844"(polysome)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0010521"(telomerase inhibitor activity)|go:"GO:0030425"(dendrite)|go:"GO:0031011"(Ino80 complex)|go:"GO:0034046"("poly(G) binding")|go:"GO:0043204"(perikaryon)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0044545"(NSL complex)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0071339"(MLL1 complex)|go:"GO:1904357"(negative regulation of telomere maintenance via telomere lengthening)|go:"GO:1904751"(positive regulation of protein localization to nucleolus)|interpro:IPR000253(Forkhead-associated)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR025999|interpro:IPR037912|mint:Q96EZ8|reactome:R-HSA-3214847|go:"GO:0043984"(histone H4-K16 acetylation)|reactome:R-HSA-5689603|reactome:R-HSA-5696394|refseq:NP_001012300.1|refseq:NP_006328.2|refseq:NP_001265270.1|refseq:XP_005268629.1|refseq:XP_016874178.1|refseq:XP_016874179.1 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:OncFlxfcbNZGN68Sk39CRh9oQHc9606 rogid:b6u2XbKLMDkL1zbLTPBjq9J23Zs9606 rigid:6bMEfQoBNWzM+oI12nh9FRkmv0Q false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P25490 uniprotkb:P78347 intact:EBI-765538|uniprotkb:Q14935|ensembl:ENSP00000262238 intact:EBI-359622|uniprotkb:Q75M88|uniprotkb:O14743|uniprotkb:O15359|uniprotkb:O43546|uniprotkb:O43588|uniprotkb:O43589|uniprotkb:Q9BSZ4|uniprotkb:Q86U51|uniprotkb:Q75M85|uniprotkb:Q75M86|uniprotkb:Q75M87|ensembl:ENSP00000460070 psi-mi:tyy1_human(display_long)|uniprotkb:Yin and yang 1(gene name synonym)|uniprotkb:Delta transcription factor(gene name synonym)|uniprotkb:NF-E1(gene name synonym)|uniprotkb:YY1(gene name)|psi-mi:YY1(display_short)|uniprotkb:INO80S(gene name synonym)|uniprotkb:INO80 complex subunit S(gene name synonym) psi-mi:gtf2i_human(display_long)|uniprotkb:GTF2I(gene name)|psi-mi:GTF2I(display_short)|uniprotkb:BAP135(gene name synonym)|uniprotkb:WBSCR6(gene name synonym)|uniprotkb:Bruton tyrosine kinase-associated protein 135(gene name synonym)|uniprotkb:SRF-Phox1-interacting protein(gene name synonym)|uniprotkb:Williams-Beuren syndrome chromosomal region 6 protein(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487000|imex:IM-26985-379 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003394.1|dip:DIP-150N|ensembl:ENSG00000100811(gene)|rcsb pdb:1UBD|rcsb pdb:1ZNM|rcsb pdb:4C5I|reactome:R-HSA-5617472|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8866910|reactome:R-HSA-9018519|ensembl:ENST00000262238(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006403"(RNA localization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010225"(response to UV-C)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034696"(response to prostaglandin F)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048468"(cell development)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0051276"(chromosome organization)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017114(Transcription factor yin and yang)|interpro:IPR036236|mint:P25490 refseq:NP_001509.3|refseq:NP_127492.1|refseq:NP_127493.1|refseq:NP_127494.1|ensembl:ENSG00000263001(gene)|ensembl:ENST00000573035(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0051481"(negative regulation of cytosolic calcium ion concentration)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0100026"(positive regulation of DNA repair by transcription from RNA polymerase II promoter)|interpro:IPR004212(GTF2I-like repeat)|interpro:IPR016659(Transcription factor II-I)|mint:P78347|rcsb pdb:2D9B|rcsb pdb:2DN4|rcsb pdb:2ED2|rcsb pdb:2EJE|interpro:IPR036647|refseq:NP_001157108.1|refseq:NP_001267729.1|dip:DIP-24252N - - comment:"author score: 22" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:OncFlxfcbNZGN68Sk39CRh9oQHc9606 rogid:DqfrIS0Ey+XvZfTXmk9KQzBtQo49606 rigid:6bMEfQoBNWzM+oI12nh9FRkmv0Q false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P25490 uniprotkb:P0C1Z6 intact:EBI-765538|uniprotkb:Q14935|ensembl:ENSP00000262238 intact:EBI-1245626|uniprotkb:G5E9B5|ensembl:ENSP00000375639|ensembl:ENSP00000477775|ensembl:ENSP00000480169|ensembl:ENSP00000480353|ensembl:ENSP00000481443|ensembl:ENSP00000482185|ensembl:ENSP00000482785|ensembl:ENSP00000483417|ensembl:ENSP00000483971|ensembl:ENSP00000484685 psi-mi:tyy1_human(display_long)|uniprotkb:Yin and yang 1(gene name synonym)|uniprotkb:Delta transcription factor(gene name synonym)|uniprotkb:NF-E1(gene name synonym)|uniprotkb:YY1(gene name)|psi-mi:YY1(display_short)|uniprotkb:INO80S(gene name synonym)|uniprotkb:INO80 complex subunit S(gene name synonym) psi-mi:tfpt_human(display_long)|uniprotkb:TFPT(gene name)|psi-mi:TFPT(display_short)|uniprotkb:Protein FB1(gene name synonym)|uniprotkb:INO80F(gene name synonym)|uniprotkb:INO80 complex subunit F(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487000|imex:IM-26985-379 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003394.1|dip:DIP-150N|ensembl:ENSG00000100811(gene)|rcsb pdb:1UBD|rcsb pdb:1ZNM|rcsb pdb:4C5I|reactome:R-HSA-5617472|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8866910|reactome:R-HSA-9018519|ensembl:ENST00000262238(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006403"(RNA localization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010225"(response to UV-C)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034696"(response to prostaglandin F)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048468"(cell development)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0051276"(chromosome organization)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017114(Transcription factor yin and yang)|interpro:IPR036236|mint:P25490 refseq:NP_037474.1|refseq:NP_001308721.1|ensembl:ENSG00000105619(gene)|ensembl:ENSG00000273833(gene)|ensembl:ENSG00000274073(gene)|ensembl:ENSG00000275086(gene)|ensembl:ENSG00000276022(gene)|ensembl:ENSG00000276263(gene)|ensembl:ENSG00000276296(gene)|ensembl:ENSG00000276323(gene)|ensembl:ENSG00000276504(gene)|ensembl:ENSG00000278161(gene)|ensembl:ENST00000391759(transcript)|ensembl:ENST00000611514(transcript)|ensembl:ENST00000611935(transcript)|ensembl:ENST00000614788(transcript)|ensembl:ENST00000615534(transcript)|ensembl:ENST00000615620(transcript)|ensembl:ENST00000616277(transcript)|ensembl:ENST00000616798(transcript)|ensembl:ENST00000617348(transcript)|ensembl:ENST00000619581(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0031011"(Ino80 complex)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0097190"(apoptotic signaling pathway)|interpro:IPR033555|mint:P0C1Z6|reactome:R-HSA-5689603|reactome:R-HSA-5696394 - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:OncFlxfcbNZGN68Sk39CRh9oQHc9606 rogid:juI/3gZemjc0hnXDJ9J+bIQ9pBw9606 rigid:6bMEfQoBNWzM+oI12nh9FRkmv0Q false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P25490 uniprotkb:Q8NBZ0 intact:EBI-765538|uniprotkb:Q14935|ensembl:ENSP00000262238 intact:EBI-769401|uniprotkb:Q6Y2K3|intact:EBI-28973946|ensembl:ENSP00000457016 psi-mi:tyy1_human(display_long)|uniprotkb:Yin and yang 1(gene name synonym)|uniprotkb:Delta transcription factor(gene name synonym)|uniprotkb:NF-E1(gene name synonym)|uniprotkb:YY1(gene name)|psi-mi:YY1(display_short)|uniprotkb:INO80S(gene name synonym)|uniprotkb:INO80 complex subunit S(gene name synonym) psi-mi:in80e_human(display_long)|uniprotkb:CCDC95(gene name synonym)|uniprotkb:Coiled-coil domain-containing protein 95(gene name synonym)|uniprotkb:INO80E(gene name)|psi-mi:INO80E(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487000|imex:IM-26985-379 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003394.1|dip:DIP-150N|ensembl:ENSG00000100811(gene)|rcsb pdb:1UBD|rcsb pdb:1ZNM|rcsb pdb:4C5I|reactome:R-HSA-5617472|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8866910|reactome:R-HSA-9018519|ensembl:ENST00000262238(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006403"(RNA localization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010225"(response to UV-C)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034696"(response to prostaglandin F)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048468"(cell development)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0051276"(chromosome organization)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017114(Transcription factor yin and yang)|interpro:IPR036236|mint:P25490 refseq:NP_775889.1|ensembl:ENST00000562441|ensembl:ENSP00000456073|ensembl:ENSP00000457016|ensembl:ENST00000567065|ensembl:ENSP00000454665|ensembl:ENST00000620599|ensembl:ENSP00000484187|refseq:NP_001291491.1|refseq:NP_001291492.1|ensembl:ENSG00000169592(gene)|ensembl:ENST00000563197(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0031011"(Ino80 complex)|interpro:IPR026678|mint:Q8NBZ0|reactome:R-HSA-5689603|reactome:R-HSA-5696394 - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:OncFlxfcbNZGN68Sk39CRh9oQHc9606 rogid:gGBXpYQkxY5mcF4I/4rTzjXZbG09606 rigid:6bMEfQoBNWzM+oI12nh9FRkmv0Q false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P25490 uniprotkb:Q9ULG1 intact:EBI-765538|uniprotkb:Q14935|ensembl:ENSP00000262238 intact:EBI-769345|uniprotkb:Q9NTG6|uniprotkb:A6H8X4|ensembl:ENSP00000384686|ensembl:ENSP00000497609 psi-mi:tyy1_human(display_long)|uniprotkb:Yin and yang 1(gene name synonym)|uniprotkb:Delta transcription factor(gene name synonym)|uniprotkb:NF-E1(gene name synonym)|uniprotkb:YY1(gene name)|psi-mi:YY1(display_short)|uniprotkb:INO80S(gene name synonym)|uniprotkb:INO80 complex subunit S(gene name synonym) psi-mi:ino80_human(display_long)|uniprotkb:INO80A(gene name synonym)|uniprotkb:INO80 complex subunit A(gene name synonym)|uniprotkb:DNA helicase-related INO80 complex homolog 1(gene name synonym)|uniprotkb:INO80(gene name)|psi-mi:INO80(display_short)|uniprotkb:KIAA1259(gene name synonym)|uniprotkb:INOC1(gene name synonym)|uniprotkb:DNA helicase-related protein INO80(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487000|imex:IM-26985-379 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003394.1|dip:DIP-150N|ensembl:ENSG00000100811(gene)|rcsb pdb:1UBD|rcsb pdb:1ZNM|rcsb pdb:4C5I|reactome:R-HSA-5617472|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8866910|reactome:R-HSA-9018519|ensembl:ENST00000262238(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006403"(RNA localization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010225"(response to UV-C)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034696"(response to prostaglandin F)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048468"(cell development)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0051276"(chromosome organization)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017114(Transcription factor yin and yang)|interpro:IPR036236|mint:P25490 refseq:NP_060023.1|dip:DIP-34296N|ensembl:ENSG00000128908(gene)|ensembl:ENST00000401393(transcript)|ensembl:ENST00000648947(transcript)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0003677"(DNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0008094"(ATP-dependent activity, acting on DNA)|go:"GO:0010571"(positive regulation of nuclear cell cycle DNA replication)|go:"GO:0016604"(nuclear body)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031011"(Ino80 complex)|go:"GO:0034644"(cellular response to UV)|go:"GO:0042393"(histone binding)|go:"GO:0042766"(nucleosome mobilization)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0043044"|go:"GO:0043618"(regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0070615"|go:"GO:0070914"(UV-damage excision repair)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000045"(regulation of G1/S transition of mitotic cell cycle)|interpro:IPR000330(SNF2-related)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|go:"GO:0000724"(double-strand break repair via homologous recombination)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR020838|interpro:IPR027417|interpro:IPR031047|interpro:IPR038718|mint:Q9ULG1|rcsb pdb:6HTS|reactome:R-HSA-5689603|reactome:R-HSA-5696394 - - comment:"author score: 30" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:OncFlxfcbNZGN68Sk39CRh9oQHc9606 rogid:HmAPLhnl6NkjlTtWgaOTufUcTgs9606 rigid:6bMEfQoBNWzM+oI12nh9FRkmv0Q false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P25490 uniprotkb:Q6P4R8 intact:EBI-765538|uniprotkb:Q14935|ensembl:ENSP00000262238 intact:EBI-2511210|ensembl:ENSP00000400476|ensembl:ENSP00000433572|ensembl:ENSP00000506850|uniprotkb:Q12869|uniprotkb:Q9H048|uniprotkb:Q15312 psi-mi:tyy1_human(display_long)|uniprotkb:Yin and yang 1(gene name synonym)|uniprotkb:Delta transcription factor(gene name synonym)|uniprotkb:NF-E1(gene name synonym)|uniprotkb:YY1(gene name)|psi-mi:YY1(display_short)|uniprotkb:INO80S(gene name synonym)|uniprotkb:INO80 complex subunit S(gene name synonym) psi-mi:nfrkb_human(display_long)|uniprotkb:NFRKB(gene name)|psi-mi:NFRKB(display_short)|uniprotkb:INO80G(gene name synonym)|uniprotkb:DNA-binding protein R kappa-B(gene name synonym)|uniprotkb:INO80 complex subunit G(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487000|imex:IM-26985-379 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003394.1|dip:DIP-150N|ensembl:ENSG00000100811(gene)|rcsb pdb:1UBD|rcsb pdb:1ZNM|rcsb pdb:4C5I|reactome:R-HSA-5617472|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8866910|reactome:R-HSA-9018519|ensembl:ENST00000262238(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006403"(RNA localization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010225"(response to UV-C)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034696"(response to prostaglandin F)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048468"(cell development)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0051276"(chromosome organization)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017114(Transcription factor yin and yang)|interpro:IPR036236|mint:P25490 ensembl:ENSG00000170322(gene)|ensembl:ENST00000446488(transcript)|ensembl:ENST00000524746(transcript)|ensembl:ENST00000682444(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0031011"(Ino80 complex)|interpro:IPR024867|interpro:IPR025220|interpro:IPR038106|interpro:IPR044867|mint:Q6P4R8|rcsb pdb:3U21|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-5689603|reactome:R-HSA-5696394|refseq:XP_011541153.1|refseq:XP_011541154.1|refseq:NP_001137307.1|refseq:NP_006156.2|refseq:XP_016873285.1 - - comment:"author score: 33" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:OncFlxfcbNZGN68Sk39CRh9oQHc9606 rogid:3eKREgXAhhBBuj4ZcG0tm4Iar3g9606 rigid:6bMEfQoBNWzM+oI12nh9FRkmv0Q false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P25490 uniprotkb:Q9Y5K5 intact:EBI-765538|uniprotkb:Q14935|ensembl:ENSP00000262238 intact:EBI-1051183|uniprotkb:Q5LJA6|uniprotkb:Q5LJA7|uniprotkb:Q8TBS4|uniprotkb:Q96BJ9|uniprotkb:Q9H1W5|uniprotkb:Q9P0I3|uniprotkb:Q9UQN2|ensembl:ENSP00000356425 psi-mi:tyy1_human(display_long)|uniprotkb:Yin and yang 1(gene name synonym)|uniprotkb:Delta transcription factor(gene name synonym)|uniprotkb:NF-E1(gene name synonym)|uniprotkb:YY1(gene name)|psi-mi:YY1(display_short)|uniprotkb:INO80S(gene name synonym)|uniprotkb:INO80 complex subunit S(gene name synonym) psi-mi:uchl5_human(display_long)|uniprotkb:Ubiquitin thioesterase L5(gene name synonym)|uniprotkb:Ubiquitin C-terminal hydrolase UCH37(gene name synonym)|uniprotkb:UCHL5(gene name)|psi-mi:UCHL5(display_short)|uniprotkb:UCH37(gene name synonym)|uniprotkb:AD-019(orf name)|uniprotkb:CGI-70(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487000|imex:IM-26985-379 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003394.1|dip:DIP-150N|ensembl:ENSG00000100811(gene)|rcsb pdb:1UBD|rcsb pdb:1ZNM|rcsb pdb:4C5I|reactome:R-HSA-5617472|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8866910|reactome:R-HSA-9018519|ensembl:ENST00000262238(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006403"(RNA localization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010225"(response to UV-C)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034696"(response to prostaglandin F)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048468"(cell development)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0051276"(chromosome organization)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017114(Transcription factor yin and yang)|interpro:IPR036236|mint:P25490 refseq:NP_001186190.1|refseq:NP_001186191.1|refseq:NP_001186192.1|refseq:NP_057068.1|ensembl:ENSG00000116750(gene)|ensembl:ENST00000367455(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0030901"(midbrain development)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031597"(cytosolic proteasome complex)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0048853"(forebrain morphogenesis)|go:"GO:0061136"(regulation of proteasomal protein catabolic process)|go:"GO:0070628"(proteasome binding)|interpro:IPR001578(Peptidase C12, ubiquitin carboxyl-terminal hydrolase 1)|interpro:IPR017390(Ubiquitinyl hydrolase, UCH37 type)|interpro:IPR033837|interpro:IPR036959|interpro:IPR038765|interpro:IPR041507|mint:Q9Y5K5|rcsb pdb:3A7S|rcsb pdb:3IHR|rcsb pdb:3RII|rcsb pdb:3RIS|rcsb pdb:3TB3|rcsb pdb:4UEL|rcsb pdb:4UEM|rcsb pdb:4UF5|rcsb pdb:4UF6|rcsb pdb:4WLP|reactome:R-HSA-2173788|reactome:R-HSA-5689603|dip:DIP-42671N - - comment:"author score: 33" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:OncFlxfcbNZGN68Sk39CRh9oQHc9606 rogid:gRm5ttq5Tc0cBIOQ1ut2ugzbMTY9606 rigid:6bMEfQoBNWzM+oI12nh9FRkmv0Q false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P25490 uniprotkb:Q9H981 intact:EBI-765538|uniprotkb:Q14935|ensembl:ENSP00000262238 intact:EBI-769597|uniprotkb:Q9H663|uniprotkb:B3KSW7|uniprotkb:Q8N566|ensembl:ENSP00000336842 psi-mi:tyy1_human(display_long)|uniprotkb:Yin and yang 1(gene name synonym)|uniprotkb:Delta transcription factor(gene name synonym)|uniprotkb:NF-E1(gene name synonym)|uniprotkb:YY1(gene name)|psi-mi:YY1(display_short)|uniprotkb:INO80S(gene name synonym)|uniprotkb:INO80 complex subunit S(gene name synonym) psi-mi:arp8_human(display_long)|uniprotkb:ACTR8(gene name)|psi-mi:ACTR8(display_short)|uniprotkb:INO80N(gene name synonym)|uniprotkb:INO80 complex subunit N(gene name synonym)|uniprotkb:ARP8(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487000|imex:IM-26985-379 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_003394.1|dip:DIP-150N|ensembl:ENSG00000100811(gene)|rcsb pdb:1UBD|rcsb pdb:1ZNM|rcsb pdb:4C5I|reactome:R-HSA-5617472|reactome:R-HSA-5689603|reactome:R-HSA-5696394|reactome:R-HSA-8866910|reactome:R-HSA-9018519|ensembl:ENST00000262238(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000400"(four-way junction DNA binding)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001217"(DNA-binding transcription repressor activity)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005677"(chromatin silencing complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006403"(RNA localization)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010225"(response to UV-C)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016363"(nuclear matrix)|go:"GO:0030183"(B cell differentiation)|go:"GO:0031011"(Ino80 complex)|go:"GO:0031519"(PcG protein complex)|go:"GO:0032688"(negative regulation of interferon-beta production)|go:"GO:0034644"(cellular response to UV)|go:"GO:0034696"(response to prostaglandin F)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046332"(SMAD binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048468"(cell development)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0051276"(chromosome organization)|go:"GO:0061052"(negative regulation of cell growth involved in cardiac muscle cell development)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071707"(immunoglobulin heavy chain V-D-J recombination)|go:"GO:1902894"(negative regulation of miRNA transcription)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR017114(Transcription factor yin and yang)|interpro:IPR036236|mint:P25490 refseq:NP_075050.3|refseq:XP_005265644.1|refseq:XP_011532551.1|ensembl:ENSG00000113812(gene)|ensembl:ENST00000335754(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0031011"(Ino80 complex)|go:"GO:0043044"|go:"GO:0051301"(cell division)|interpro:IPR004000(Actin/actin-like)|interpro:IPR027668|interpro:IPR043129|mint:Q9H981|rcsb pdb:4FO0|reactome:R-HSA-5689603|reactome:R-HSA-5696394 - - comment:"author score: 36" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:OncFlxfcbNZGN68Sk39CRh9oQHc9606 rogid:9bgkh+pDd9OCLZEW1uWg4fXjBIk9606 rigid:6bMEfQoBNWzM+oI12nh9FRkmv0Q false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N5A5 uniprotkb:P11532 intact:EBI-3439227|uniprotkb:Q5JWI9|uniprotkb:Q8WUV4|uniprotkb:Q9H401|uniprotkb:Q96JU4|uniprotkb:Q96JI0|uniprotkb:Q8NC55|uniprotkb:Q5JWJ0|uniprotkb:Q4VXN9|uniprotkb:E1P5K1|ensembl:ENSP00000332013 intact:EBI-295827|uniprotkb:Q9UCW3|uniprotkb:Q9UCW4|uniprotkb:Q02295|uniprotkb:Q14169|uniprotkb:Q14170|uniprotkb:Q5JYU0|uniprotkb:Q7KZ48|intact:EBI-11041646|uniprotkb:A1L0U9|uniprotkb:Q8N754|uniprotkb:E9PDN1|uniprotkb:Q6NSJ9|intact:EBI-12189729|intact:EBI-22423597|intact:EBI-12702600|uniprotkb:E7EQR9|uniprotkb:E7EQS5|uniprotkb:E7ESB2|uniprotkb:E9PDN5|uniprotkb:F5GZY3|uniprotkb:F8VX32|intact:EBI-28985510 psi-mi:zgpat_human(display_long)|uniprotkb:ZGPAT(gene name)|psi-mi:ZGPAT(display_short)|uniprotkb:GPATC6(gene name synonym)|uniprotkb:GPATCH6(gene name synonym)|uniprotkb:KIAA1847(gene name synonym)|uniprotkb:ZC3H9(gene name synonym)|uniprotkb:ZC3HDC9(gene name synonym)|uniprotkb:ZIP(gene name synonym)|uniprotkb:G patch domain-containing protein 6(gene name synonym)|uniprotkb:Zinc finger CCCH domain-containing protein 9(gene name synonym)|uniprotkb:Zinc finger and G patch domain-containing protein(gene name synonym) psi-mi:dmd_human(display_long)|uniprotkb:DMD(gene name)|psi-mi:DMD(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487045|imex:IM-26985-239 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001076582.1|refseq:NP_001182582.1|refseq:NP_001182583.1|refseq:NP_115916.3|refseq:NP_852150.2|ensembl:ENSG00000197114(gene)|ensembl:ENST00000328969(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR000467(D111/G-patch)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR002999(Tudor)|interpro:IPR036855|interpro:IPR041367|interpro:IPR043560|mint:Q8N5A5|rcsb pdb:4II1 refseq:NP_000100.2|refseq:NP_003997.1|refseq:NP_004000.1|refseq:NP_004001.1|refseq:NP_004002.2|refseq:NP_004003.1|refseq:NP_004004.1|refseq:NP_004005.1|refseq:NP_004008.1|refseq:NP_004009.1|refseq:NP_004010.1|refseq:NP_004011.2|refseq:NP_004012.1|refseq:NP_004013.1|refseq:NP_004014.1|refseq:NP_004006.1|refseq:NP_004007.1|ensembl:ENST00000682600|ensembl:ENSP00000507640|ensembl:ENST00000361471|ensembl:ENSP00000354464|ensembl:ENSG00000198947|ensembl:ENST00000378680|ensembl:ENSP00000367951|ensembl:ENST00000378702|ensembl:ENSP00000367974|ensembl:ENST00000378723|ensembl:ENSP00000367997|mint:P11532|dip:DIP-32593N|go:"GO:0002027"(regulation of heart rate)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007517"(muscle organ development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0009986"(cell surface)|go:"GO:0010880"(regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum)|go:"GO:0010881"(regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014809"(regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion)|go:"GO:0014819"(regulation of skeletal muscle contraction)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016013"(syntrophin complex)|go:"GO:0017022"(myosin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0030018"(Z disc)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030175"(filopodium)|go:"GO:0031527"(filopodium membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034622"|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043043"(peptide biosynthetic process)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0044458"(motile cilium assembly)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0055001"(muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0060314"(regulation of ryanodine-sensitive calcium-release channel activity)|go:"GO:0086001"(cardiac muscle cell action potential)|go:"GO:0090287"(regulation of cellular response to growth factor stimulus)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|rcsb pdb:1DXX|rcsb pdb:1EG3|rcsb pdb:1EG4|rcsb pdb:3UUN|reactome:R-HSA-3000171|reactome:R-HSA-390522 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y65Y35/UuhP6dcxRmNZDjEHE4MI9606 rogid:gUFSTsQjsZpAmGI3+6ZPmUebofA9606 rigid:zVCiwow8mIX8/WRzmDX3X8CI438 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N5A5 uniprotkb:O43172 intact:EBI-3439227|uniprotkb:Q5JWI9|uniprotkb:Q8WUV4|uniprotkb:Q9H401|uniprotkb:Q96JU4|uniprotkb:Q96JI0|uniprotkb:Q8NC55|uniprotkb:Q5JWJ0|uniprotkb:Q4VXN9|uniprotkb:E1P5K1|ensembl:ENSP00000332013 intact:EBI-718395|uniprotkb:O43445|uniprotkb:O43864|uniprotkb:Q96DG2|uniprotkb:Q96IK4|uniprotkb:Q5T1M8|ensembl:ENSP00000363315 psi-mi:zgpat_human(display_long)|uniprotkb:ZGPAT(gene name)|psi-mi:ZGPAT(display_short)|uniprotkb:GPATC6(gene name synonym)|uniprotkb:GPATCH6(gene name synonym)|uniprotkb:KIAA1847(gene name synonym)|uniprotkb:ZC3H9(gene name synonym)|uniprotkb:ZC3HDC9(gene name synonym)|uniprotkb:ZIP(gene name synonym)|uniprotkb:G patch domain-containing protein 6(gene name synonym)|uniprotkb:Zinc finger CCCH domain-containing protein 9(gene name synonym)|uniprotkb:Zinc finger and G patch domain-containing protein(gene name synonym) psi-mi:prp4_human(display_long)|uniprotkb:U4/U6 snRNP 60 kDa protein(gene name synonym)|uniprotkb:WD splicing factor Prp4(gene name synonym)|uniprotkb:PRP4 homolog(gene name synonym)|uniprotkb:PRPF4(gene name)|psi-mi:PRPF4(display_short)|uniprotkb:PRP4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487045|imex:IM-26985-239 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001076582.1|refseq:NP_001182582.1|refseq:NP_001182583.1|refseq:NP_115916.3|refseq:NP_852150.2|ensembl:ENSG00000197114(gene)|ensembl:ENST00000328969(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR000467(D111/G-patch)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR002999(Tudor)|interpro:IPR036855|interpro:IPR041367|interpro:IPR043560|mint:Q8N5A5|rcsb pdb:4II1 refseq:NP_004688.2|refseq:NP_001231855.1|ensembl:ENSG00000136875(gene)|ensembl:ENST00000374199(transcript)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0046540"(U4/U6 x U5 tri-snRNP complex)|go:"GO:0071001"(U4/U6 snRNP)|go:"GO:0071005"(U2-type precatalytic spliceosome)|go:"GO:0097525"(spliceosomal snRNP complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR014906("Pre-mRNA processing factor 4 (PRP4) like")|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|interpro:IPR015943(WD40/YVTN repeat-like)|go:"GO:0006396"(RNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0015030"(Cajal body)|go:"GO:0016607"(nuclear speck)|go:"GO:0017070"(U6 snRNA binding)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036285|interpro:IPR036322|mint:O43172|rcsb pdb:1MZW|rcsb pdb:3JCR|rcsb pdb:5O9Z|rcsb pdb:6AH0|rcsb pdb:6AHD|rcsb pdb:6QW6|rcsb pdb:6QX9|reactome:R-HSA-72163|go:"GO:0030621"(U4 snRNA binding) - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y65Y35/UuhP6dcxRmNZDjEHE4MI9606 rogid:PPTNuhEFj4D+gTv/ctTTMzGmFA09606 rigid:zVCiwow8mIX8/WRzmDX3X8CI438 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N5A5 uniprotkb:Q9UBT7 intact:EBI-3439227|uniprotkb:Q5JWI9|uniprotkb:Q8WUV4|uniprotkb:Q9H401|uniprotkb:Q96JU4|uniprotkb:Q96JI0|uniprotkb:Q8NC55|uniprotkb:Q5JWJ0|uniprotkb:Q4VXN9|uniprotkb:E1P5K1|ensembl:ENSP00000332013 intact:EBI-514206|uniprotkb:O76084|uniprotkb:Q53FQ2|uniprotkb:Q5JTQ7|uniprotkb:Q5JTQ8|uniprotkb:Q9Y401|uniprotkb:B5BU47|ensembl:ENSP00000320434 psi-mi:zgpat_human(display_long)|uniprotkb:ZGPAT(gene name)|psi-mi:ZGPAT(display_short)|uniprotkb:GPATC6(gene name synonym)|uniprotkb:GPATCH6(gene name synonym)|uniprotkb:KIAA1847(gene name synonym)|uniprotkb:ZC3H9(gene name synonym)|uniprotkb:ZC3HDC9(gene name synonym)|uniprotkb:ZIP(gene name synonym)|uniprotkb:G patch domain-containing protein 6(gene name synonym)|uniprotkb:Zinc finger CCCH domain-containing protein 9(gene name synonym)|uniprotkb:Zinc finger and G patch domain-containing protein(gene name synonym) psi-mi:ctnl1_human(display_long)|uniprotkb:Catenin alpha-like protein 1(gene name synonym)|uniprotkb:Alpha-catenin-related protein(gene name synonym)|uniprotkb:CTNNAL1(gene name)|psi-mi:CTNNAL1(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487045|imex:IM-26985-239 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001076582.1|refseq:NP_001182582.1|refseq:NP_001182583.1|refseq:NP_115916.3|refseq:NP_852150.2|ensembl:ENSG00000197114(gene)|ensembl:ENST00000328969(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR000467(D111/G-patch)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR002999(Tudor)|interpro:IPR036855|interpro:IPR041367|interpro:IPR043560|mint:Q8N5A5|rcsb pdb:4II1 refseq:NP_003789.1|refseq:NP_001273903.1|dip:DIP-33236N|ensembl:ENSG00000119326(gene)|ensembl:ENST00000325551(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR030045|interpro:IPR036723|mint:Q9UBT7 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y65Y35/UuhP6dcxRmNZDjEHE4MI9606 rogid:4XpDxeBmUk7NAT/aAAhl0c8Sc1w9606 rigid:zVCiwow8mIX8/WRzmDX3X8CI438 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N5A5 uniprotkb:Q86X55 intact:EBI-3439227|uniprotkb:Q5JWI9|uniprotkb:Q8WUV4|uniprotkb:Q9H401|uniprotkb:Q96JU4|uniprotkb:Q96JI0|uniprotkb:Q8NC55|uniprotkb:Q5JWJ0|uniprotkb:Q4VXN9|uniprotkb:E1P5K1|ensembl:ENSP00000332013 intact:EBI-2339854|uniprotkb:A6NN38|ensembl:ENSP00000325690 psi-mi:zgpat_human(display_long)|uniprotkb:ZGPAT(gene name)|psi-mi:ZGPAT(display_short)|uniprotkb:GPATC6(gene name synonym)|uniprotkb:GPATCH6(gene name synonym)|uniprotkb:KIAA1847(gene name synonym)|uniprotkb:ZC3H9(gene name synonym)|uniprotkb:ZC3HDC9(gene name synonym)|uniprotkb:ZIP(gene name synonym)|uniprotkb:G patch domain-containing protein 6(gene name synonym)|uniprotkb:Zinc finger CCCH domain-containing protein 9(gene name synonym)|uniprotkb:Zinc finger and G patch domain-containing protein(gene name synonym) psi-mi:carm1_human(display_long)|uniprotkb:CARM1(gene name)|psi-mi:CARM1(display_short)|uniprotkb:PRMT4(gene name synonym)|uniprotkb:Protein arginine N-methyltransferase 4(gene name synonym)|uniprotkb:Coactivator-associated arginine methyltransferase 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487045|imex:IM-26985-239 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001076582.1|refseq:NP_001182582.1|refseq:NP_001182583.1|refseq:NP_115916.3|refseq:NP_852150.2|ensembl:ENSG00000197114(gene)|ensembl:ENST00000328969(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR000467(D111/G-patch)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR002999(Tudor)|interpro:IPR036855|interpro:IPR041367|interpro:IPR043560|mint:Q8N5A5|rcsb pdb:4II1 refseq:NP_954592.1|refseq:XP_005259765.1|dip:DIP-44071N|ensembl:ENSG00000142453(gene)|ensembl:ENST00000327064(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007568"(aging)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008469"(histone-arginine N-methyltransferase activity)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0030374"(nuclear receptor coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0034970"(histone H3-R2 methylation)|go:"GO:0034971"(histone H3-R17 methylation)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0035642"("histone methyltransferase activity (H3-R17 specific)")|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0070577"(lysine-acetylated histone binding)|go:"GO:1902415"(regulation of mRNA binding)|go:"GO:2000171"(negative regulation of dendrite development)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020989|interpro:IPR025799|interpro:IPR029063|mint:Q86X55|rcsb pdb:2Y1W|rcsb pdb:2Y1X|rcsb pdb:4IKP|rcsb pdb:5DWQ|rcsb pdb:5DX0|rcsb pdb:5DX1|rcsb pdb:5DX8|rcsb pdb:5DXA|rcsb pdb:5DXJ|rcsb pdb:5U4X|rcsb pdb:6ARJ|rcsb pdb:6ARV|rcsb pdb:6D2L|rcsb pdb:6DVR|rcsb pdb:6IZQ|rcsb pdb:6S70|rcsb pdb:6S71|rcsb pdb:6S74|rcsb pdb:6S77|rcsb pdb:6S79|rcsb pdb:6S7A|rcsb pdb:6S7B|rcsb pdb:6S7C|reactome:R-HSA-1368082|reactome:R-HSA-1368108|reactome:R-HSA-1989781|reactome:R-HSA-2151201|reactome:R-HSA-2426168|reactome:R-HSA-3214858|reactome:R-HSA-381340|reactome:R-HSA-400206|reactome:R-HSA-400253|reactome:R-HSA-6804114|reactome:R-HSA-9018519|reactome:R-HSA-9707564|reactome:R-HSA-9707616|go:"GO:0051591"(response to cAMP) - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y65Y35/UuhP6dcxRmNZDjEHE4MI9606 rogid:1x1bUjqcA/ZpmrSsSM545ReYH2A9606 rigid:zVCiwow8mIX8/WRzmDX3X8CI438 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N5A5 uniprotkb:Q13884 intact:EBI-3439227|uniprotkb:Q5JWI9|uniprotkb:Q8WUV4|uniprotkb:Q9H401|uniprotkb:Q96JU4|uniprotkb:Q96JI0|uniprotkb:Q8NC55|uniprotkb:Q5JWJ0|uniprotkb:Q4VXN9|uniprotkb:E1P5K1|ensembl:ENSP00000332013 intact:EBI-295843|uniprotkb:O14912|uniprotkb:Q4KMG8|uniprotkb:A8K9E0|ensembl:ENSP00000378965|ensembl:ENSP00000431124 psi-mi:zgpat_human(display_long)|uniprotkb:ZGPAT(gene name)|psi-mi:ZGPAT(display_short)|uniprotkb:GPATC6(gene name synonym)|uniprotkb:GPATCH6(gene name synonym)|uniprotkb:KIAA1847(gene name synonym)|uniprotkb:ZC3H9(gene name synonym)|uniprotkb:ZC3HDC9(gene name synonym)|uniprotkb:ZIP(gene name synonym)|uniprotkb:G patch domain-containing protein 6(gene name synonym)|uniprotkb:Zinc finger CCCH domain-containing protein 9(gene name synonym)|uniprotkb:Zinc finger and G patch domain-containing protein(gene name synonym) psi-mi:sntb1_human(display_long)|uniprotkb:SNTB1(gene name)|psi-mi:SNTB1(display_short)|uniprotkb:SNT2B1(gene name synonym)|uniprotkb:59 kDa dystrophin-associated protein A1 basic component 1(gene name synonym)|uniprotkb:Tax interaction protein 43(gene name synonym)|uniprotkb:Syntrophin-2(gene name synonym)|uniprotkb:BSYN2(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487045|imex:IM-26985-239 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001076582.1|refseq:NP_001182582.1|refseq:NP_001182583.1|refseq:NP_115916.3|refseq:NP_852150.2|ensembl:ENSG00000197114(gene)|ensembl:ENST00000328969(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR000467(D111/G-patch)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR002999(Tudor)|interpro:IPR036855|interpro:IPR041367|interpro:IPR043560|mint:Q8N5A5|rcsb pdb:4II1 refseq:XP_011515541.1|refseq:NP_066301.1|dip:DIP-466N|ensembl:ENSG00000172164(gene)|ensembl:ENST00000395601(transcript)|ensembl:ENST00000517992(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0006936"(muscle contraction)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045202"(synapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR036034|interpro:IPR041428|mint:Q13884 - - comment:"author score: 41" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y65Y35/UuhP6dcxRmNZDjEHE4MI9606 rogid:ysg02ZmUoj12kFHjpHE68vA1lUs9606 rigid:zVCiwow8mIX8/WRzmDX3X8CI438 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N5A5 uniprotkb:O60941 intact:EBI-3439227|uniprotkb:Q5JWI9|uniprotkb:Q8WUV4|uniprotkb:Q9H401|uniprotkb:Q96JU4|uniprotkb:Q96JI0|uniprotkb:Q8NC55|uniprotkb:Q5JWJ0|uniprotkb:Q4VXN9|uniprotkb:E1P5K1|ensembl:ENSP00000332013 intact:EBI-740402|intact:EBI-784159|uniprotkb:O43782|uniprotkb:O60881|ensembl:ENSP00000384084|uniprotkb:O75538|uniprotkb:Q96AW0|uniprotkb:Q9UE14|uniprotkb:Q9UE15|uniprotkb:Q9UE16|uniprotkb:G5E9F6|uniprotkb:Q86VR4|uniprotkb:B7Z733|uniprotkb:F5GZG4 psi-mi:zgpat_human(display_long)|uniprotkb:ZGPAT(gene name)|psi-mi:ZGPAT(display_short)|uniprotkb:GPATC6(gene name synonym)|uniprotkb:GPATCH6(gene name synonym)|uniprotkb:KIAA1847(gene name synonym)|uniprotkb:ZC3H9(gene name synonym)|uniprotkb:ZC3HDC9(gene name synonym)|uniprotkb:ZIP(gene name synonym)|uniprotkb:G patch domain-containing protein 6(gene name synonym)|uniprotkb:Zinc finger CCCH domain-containing protein 9(gene name synonym)|uniprotkb:Zinc finger and G patch domain-containing protein(gene name synonym) psi-mi:dtnb_human(display_long)|uniprotkb:DTNB(gene name)|psi-mi:DTNB(display_short)|uniprotkb:Beta-dystrobrevin(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487045|imex:IM-26985-239 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001076582.1|refseq:NP_001182582.1|refseq:NP_001182583.1|refseq:NP_115916.3|refseq:NP_852150.2|ensembl:ENSG00000197114(gene)|ensembl:ENST00000328969(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR000467(D111/G-patch)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR002999(Tudor)|interpro:IPR036855|interpro:IPR041367|interpro:IPR043560|mint:Q8N5A5|rcsb pdb:4II1 refseq:NP_001243232.1|refseq:NP_068707.1|refseq:NP_149159.2|refseq:NP_149160.1|refseq:NP_899204.1|ensembl:ENSG00000138101(gene)|ensembl:ENST00000406818(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008270"(zinc ion binding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030425"(dendrite)|go:"GO:0045202"(synapse)|go:"GO:0060077"(inhibitory synapse)|go:"GO:0099536"(synaptic signaling)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR017432(Distrobrevin)|interpro:IPR043145|mint:O60941|refseq:NP_001243237.1|refseq:NP_899205.1|refseq:NP_001307861.1|refseq:NP_001307862.1|refseq:NP_001307863.1|refseq:NP_001307864.1|refseq:NP_001307865.1 - - comment:"author score: 54" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y65Y35/UuhP6dcxRmNZDjEHE4MI9606 rogid:/yB9vgxJOii2Uk4riTNLOhf9gUk9606 rigid:zVCiwow8mIX8/WRzmDX3X8CI438 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N5A5 uniprotkb:Q9Y4J8 intact:EBI-3439227|uniprotkb:Q5JWI9|uniprotkb:Q8WUV4|uniprotkb:Q9H401|uniprotkb:Q96JU4|uniprotkb:Q96JI0|uniprotkb:Q8NC55|uniprotkb:Q5JWJ0|uniprotkb:Q4VXN9|uniprotkb:E1P5K1|ensembl:ENSP00000332013 intact:EBI-949471|ensembl:ENSP00000382064|uniprotkb:O15332|uniprotkb:O15333|uniprotkb:O75697|uniprotkb:Q13197|uniprotkb:Q13198|uniprotkb:Q13199|uniprotkb:Q13498|uniprotkb:Q13499|uniprotkb:Q13500|uniprotkb:A8MUY4|uniprotkb:A8K541|uniprotkb:M0QYX6|uniprotkb:A8MSZ0|uniprotkb:Q9BS59|uniprotkb:B4DIU8|uniprotkb:B4DIR0|uniprotkb:B4DGS6|uniprotkb:M0R397|uniprotkb:Q59GK7 psi-mi:zgpat_human(display_long)|uniprotkb:ZGPAT(gene name)|psi-mi:ZGPAT(display_short)|uniprotkb:GPATC6(gene name synonym)|uniprotkb:GPATCH6(gene name synonym)|uniprotkb:KIAA1847(gene name synonym)|uniprotkb:ZC3H9(gene name synonym)|uniprotkb:ZC3HDC9(gene name synonym)|uniprotkb:ZIP(gene name synonym)|uniprotkb:G patch domain-containing protein 6(gene name synonym)|uniprotkb:Zinc finger CCCH domain-containing protein 9(gene name synonym)|uniprotkb:Zinc finger and G patch domain-containing protein(gene name synonym) psi-mi:dtna_human(display_long)|uniprotkb:Alpha-dystrobrevin(gene name synonym)|uniprotkb:Dystrophin-related protein 3(gene name synonym)|uniprotkb:DTNA(gene name)|psi-mi:DTNA(display_short)|uniprotkb:DRP3(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487045|imex:IM-26985-239 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001076582.1|refseq:NP_001182582.1|refseq:NP_001182583.1|refseq:NP_115916.3|refseq:NP_852150.2|ensembl:ENSG00000197114(gene)|ensembl:ENST00000328969(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR000467(D111/G-patch)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR002999(Tudor)|interpro:IPR036855|interpro:IPR041367|interpro:IPR043560|mint:Q8N5A5|rcsb pdb:4II1 ensembl:ENSG00000134769(gene)|ensembl:ENST00000399113(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007165"(signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007274"(neuromuscular synaptic transmission)|go:"GO:0008270"(zinc ion binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030424"(axon)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045202"(synapse)|go:"GO:0099536"(synaptic signaling)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR017432(Distrobrevin)|interpro:IPR043145|mint:Q9Y4J8|rcsb pdb:2E5R|interpro:IPR000433(Zinc finger, ZZ-type)|refseq:NP_001185873.1|refseq:NP_001381.2|refseq:NP_001382.2|refseq:NP_001383.2|refseq:NP_116757.2|refseq:NP_116760.2|refseq:NP_116761.2|refseq:NP_116762.2|refseq:NP_116763.1|refseq:XP_011524155.1|refseq:NP_001121647.1|refseq:NP_001185867.1|refseq:NP_001185868.1|refseq:NP_001185871.1|refseq:NP_001185869.1|refseq:NP_001185874.1|refseq:NP_001185870.1|refseq:XP_016881066.1|refseq:XP_016881073.1|refseq:XP_016881076.1|refseq:XP_016881077.1|refseq:XP_016881078.1|refseq:XP_016881079.1|refseq:XP_016881080.1|refseq:XP_016881089.1|refseq:XP_016881090.1|refseq:XP_016881091.1 - - comment:"author score: 61" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y65Y35/UuhP6dcxRmNZDjEHE4MI9606 rogid:9HaDKLthoXmwdYDzbEer3CRN3O09606 rigid:zVCiwow8mIX8/WRzmDX3X8CI438 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N5A5 uniprotkb:P46939 intact:EBI-3439227|uniprotkb:Q5JWI9|uniprotkb:Q8WUV4|uniprotkb:Q9H401|uniprotkb:Q96JU4|uniprotkb:Q96JI0|uniprotkb:Q8NC55|uniprotkb:Q5JWJ0|uniprotkb:Q4VXN9|uniprotkb:E1P5K1|ensembl:ENSP00000332013 intact:EBI-295856|intact:EBI-784141|uniprotkb:Q5SZ57|uniprotkb:Q5SYY1|uniprotkb:Q9UJ40|ensembl:ENSP00000356515 psi-mi:zgpat_human(display_long)|uniprotkb:ZGPAT(gene name)|psi-mi:ZGPAT(display_short)|uniprotkb:GPATC6(gene name synonym)|uniprotkb:GPATCH6(gene name synonym)|uniprotkb:KIAA1847(gene name synonym)|uniprotkb:ZC3H9(gene name synonym)|uniprotkb:ZC3HDC9(gene name synonym)|uniprotkb:ZIP(gene name synonym)|uniprotkb:G patch domain-containing protein 6(gene name synonym)|uniprotkb:Zinc finger CCCH domain-containing protein 9(gene name synonym)|uniprotkb:Zinc finger and G patch domain-containing protein(gene name synonym) psi-mi:utrn_human(display_long)|uniprotkb:UTRN(gene name)|psi-mi:UTRN(display_short)|uniprotkb:DMDL(gene name synonym)|uniprotkb:Dystrophin-related protein 1(gene name synonym)|uniprotkb:DRP1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487045|imex:IM-26985-239 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001076582.1|refseq:NP_001182582.1|refseq:NP_001182583.1|refseq:NP_115916.3|refseq:NP_852150.2|ensembl:ENSG00000197114(gene)|ensembl:ENST00000328969(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR000467(D111/G-patch)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR002999(Tudor)|interpro:IPR036855|interpro:IPR041367|interpro:IPR043560|mint:Q8N5A5|rcsb pdb:4II1 ensembl:ENSP00000356515|refseq:XP_011534408.1|refseq:NP_009055.2|refseq:XP_005267187.1|dip:DIP-711N|ensembl:ENSG00000152818(gene)|ensembl:ENST00000367545(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017166"(vinculin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030175"(filopodium)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P46939|rcsb pdb:1BHD|rcsb pdb:1QAG|rcsb pdb:6M5G|reactome:R-HSA-9619665 - - comment:"author score: 74" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y65Y35/UuhP6dcxRmNZDjEHE4MI9606 rogid:metWqbqGtzonNZ1mgNjlFrenuI89606 rigid:zVCiwow8mIX8/WRzmDX3X8CI438 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q8N5A5 uniprotkb:Q13425 intact:EBI-3439227|uniprotkb:Q5JWI9|uniprotkb:Q8WUV4|uniprotkb:Q9H401|uniprotkb:Q96JU4|uniprotkb:Q96JI0|uniprotkb:Q8NC55|uniprotkb:Q5JWJ0|uniprotkb:Q4VXN9|uniprotkb:E1P5K1|ensembl:ENSP00000332013 intact:EBI-80411|ensembl:ENSP00000338191|uniprotkb:Q9BY09 psi-mi:zgpat_human(display_long)|uniprotkb:ZGPAT(gene name)|psi-mi:ZGPAT(display_short)|uniprotkb:GPATC6(gene name synonym)|uniprotkb:GPATCH6(gene name synonym)|uniprotkb:KIAA1847(gene name synonym)|uniprotkb:ZC3H9(gene name synonym)|uniprotkb:ZC3HDC9(gene name synonym)|uniprotkb:ZIP(gene name synonym)|uniprotkb:G patch domain-containing protein 6(gene name synonym)|uniprotkb:Zinc finger CCCH domain-containing protein 9(gene name synonym)|uniprotkb:Zinc finger and G patch domain-containing protein(gene name synonym) psi-mi:sntb2_human(display_long)|uniprotkb:SNT2B2(gene name synonym)|uniprotkb:SNTB2(gene name)|psi-mi:SNTB2(display_short)|uniprotkb:D16S2531E(gene name synonym)|uniprotkb:SNTL(gene name synonym)|uniprotkb:59 kDa dystrophin-associated protein A1 basic component 2(gene name synonym)|uniprotkb:Syntrophin-3(gene name synonym)|uniprotkb:Syntrophin-like(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487045|imex:IM-26985-239 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001076582.1|refseq:NP_001182582.1|refseq:NP_001182583.1|refseq:NP_115916.3|refseq:NP_852150.2|ensembl:ENSG00000197114(gene)|ensembl:ENST00000328969(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|interpro:IPR000467(D111/G-patch)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR002999(Tudor)|interpro:IPR036855|interpro:IPR041367|interpro:IPR043560|mint:Q8N5A5|rcsb pdb:4II1 go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005874"(microtubule)|go:"GO:0016020"(membrane)|go:"GO:0030658"(transport vesicle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045202"(synapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015482(Syntrophin)|interpro:IPR028550|interpro:IPR036034|interpro:IPR041428|mint:Q13425|rcsb pdb:2VRF|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|ensembl:ENSG00000168807(gene)|ensembl:ENST00000336278(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|refseq:NP_006741.1 - - comment:"author score: 106" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:y65Y35/UuhP6dcxRmNZDjEHE4MI9606 rogid:SABgmvArdLH93OpFobs/L3BleVY9606 rigid:zVCiwow8mIX8/WRzmDX3X8CI438 false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7Z2W4 uniprotkb:Q14568 intact:EBI-922540|uniprotkb:Q8TAJ3|uniprotkb:Q96N79|uniprotkb:Q9H8R9|uniprotkb:Q9P0Y7|uniprotkb:Q8IW57|uniprotkb:A4D1R2|uniprotkb:A4D1S4|ensembl:ENSP00000242351 intact:EBI-2826582 psi-mi:zcchv_human(display_long)|uniprotkb:Inactive Poly [ADP-ribose] polymerase 13(gene name synonym)|uniprotkb:ZC3HAV1(gene name)|psi-mi:ZC3HAV1(display_short)|uniprotkb:ZC3HDC2(gene name synonym)|uniprotkb:PRO1677(orf name)|uniprotkb:Zinc finger CCCH domain-containing protein 2(gene name synonym)|uniprotkb:Zinc finger antiviral protein(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 13(gene name synonym) psi-mi:hs902_human(display_long)|uniprotkb:HSP90AA2P(gene name)|psi-mi:HSP90AA2P(display_short)|uniprotkb:HSP90AA2(gene name synonym)|uniprotkb:HSPCAL3(gene name synonym)|uniprotkb:Heat shock 90 kDa protein 1 alpha-like 3(gene name synonym)|uniprotkb:Heat shock protein HSP 90-alpha A2 pseudogene(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487033|imex:IM-26985-77 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064504.2|refseq:NP_078901.3|ensembl:ENSG00000105939(gene)|ensembl:ENST00000242351(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0009615"(response to virus)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR004170(WWE)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR036388|interpro:IPR037197|interpro:IPR040954|interpro:IPR041360|mint:Q7Z2W4|rcsb pdb:2X5Y|rcsb pdb:4X52|rcsb pdb:6UEI|rcsb pdb:6UEJ|reactome:R-HSA-6802952|dip:DIP-37896N interpro:IPR003594(ATP-binding region, ATPase-like)|interpro:IPR019805|interpro:IPR001404(Heat shock protein Hsp90)|interpro:IPR020575|interpro:IPR020568|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006457"(protein folding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR036890|mint:Q14568 - - comment:"author score: 18" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:iJy4W/YX/vVXGbFd+GnfoKlo8aA9606 rogid:HN+Hui0dI60DoXKDmTqZRgIEyK49606 rigid:IbNZYanakgzO+E72nCCAU56wDMM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q7Z2W4 uniprotkb:O15037 intact:EBI-922540|uniprotkb:Q8TAJ3|uniprotkb:Q96N79|uniprotkb:Q9H8R9|uniprotkb:Q9P0Y7|uniprotkb:Q8IW57|uniprotkb:A4D1R2|uniprotkb:A4D1S4|ensembl:ENSP00000242351 intact:EBI-6148525|uniprotkb:Q86TZ6|uniprotkb:Q8IUQ2|uniprotkb:Q96BA9|ensembl:ENSP00000251343|ensembl:ENSP00000450799|ensembl:ENSP00000451106 psi-mi:zcchv_human(display_long)|uniprotkb:Inactive Poly [ADP-ribose] polymerase 13(gene name synonym)|uniprotkb:ZC3HAV1(gene name)|psi-mi:ZC3HAV1(display_short)|uniprotkb:ZC3HDC2(gene name synonym)|uniprotkb:PRO1677(orf name)|uniprotkb:Zinc finger CCCH domain-containing protein 2(gene name synonym)|uniprotkb:Zinc finger antiviral protein(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 13(gene name synonym) psi-mi:khnyn_human(display_long)|uniprotkb:KHNYN(gene name)|psi-mi:KHNYN(display_short)|uniprotkb:KH and NYN domain-containing protein(gene name synonym)|uniprotkb:KIAA0323(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487033|imex:IM-26985-77 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_064504.2|refseq:NP_078901.3|ensembl:ENSG00000105939(gene)|ensembl:ENST00000242351(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0009615"(response to virus)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR004170(WWE)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR036388|interpro:IPR037197|interpro:IPR040954|interpro:IPR041360|mint:Q7Z2W4|rcsb pdb:2X5Y|rcsb pdb:4X52|rcsb pdb:6UEI|rcsb pdb:6UEJ|reactome:R-HSA-6802952|dip:DIP-37896N refseq:NP_056114.1|refseq:XP_005267531.1|refseq:NP_001277185.1|refseq:NP_001277186.1|ensembl:ENSG00000100441(gene)|ensembl:ENST00000251343(transcript)|ensembl:ENST00000553935(transcript)|ensembl:ENST00000556842(transcript)|go:"GO:0003729"(mRNA binding)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0090502"(RNA phosphodiester bond hydrolysis, endonucleolytic)|interpro:IPR021869|interpro:IPR036612|mint:O15037|rcsb pdb:2N5M|rcsb pdb:2N7K - - comment:"author score: 47" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:iJy4W/YX/vVXGbFd+GnfoKlo8aA9606 rogid:vZgxwA7yR6mbBzxBvjkhMmhv5fY9606 rigid:IbNZYanakgzO+E72nCCAU56wDMM false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96K75 uniprotkb:P16104 intact:EBI-6660752|ensembl:ENSP00000295208|ensembl:ENSP00000405509|uniprotkb:Q5JPJ3 intact:EBI-494830|uniprotkb:Q4ZGJ7|uniprotkb:Q6IAS5|ensembl:ENSP00000364310|ensembl:ENSP00000434024 psi-mi:zn514_human(display_long)|uniprotkb:ZNF514(gene name)|psi-mi:ZNF514(display_short) psi-mi:h2ax_human(display_long)|uniprotkb:H2AX(gene name)|psi-mi:H2AX(display_short)|uniprotkb:H2AFX(gene name synonym)|uniprotkb:Histone H2A.X(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487117|imex:IM-26985-79 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000144026(gene)|ensembl:ENST00000295208(transcript)|ensembl:ENST00000411425(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|mint:Q96K75|reactome:R-HSA-212436|refseq:NP_001304934.1|refseq:NP_116177.1|refseq:XP_006712869.1 ensembl:ENSG00000188486(gene)|ensembl:ENST00000375167(transcript)|ensembl:ENST00000530167(transcript)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000786"(nucleosome)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0001673"(male germ cell nucleus)|go:"GO:0001741"(XY body)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|refseq:NP_002096.1|dip:DIP-33604N|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214858|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225|go:"GO:0005813"(centrosome)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010212"(response to ionizing radiation)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042393"(histone binding)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051321"(meiotic cell cycle)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0090398"(cellular senescence)|go:"GO:0090734"(site of DNA damage)|interpro:IPR002119(Histone H2A)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR032454|interpro:IPR032458|mint:P16104|rcsb pdb:1YDP|rcsb pdb:2AZM|rcsb pdb:2D31|rcsb pdb:2DYP|rcsb pdb:3SHV|rcsb pdb:3SQD|rcsb pdb:3SZM|rcsb pdb:3U3Z|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qw27vebM3X0BDC5K6dmpFCHIf8c9606 rogid:VQoEp3F8lEBTOj+PDDUzrJCQNZA9606 rigid:ReNfR8kesQTfUynorOEdMpZa+RY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96K75 uniprotkb:Q13595 intact:EBI-6660752|ensembl:ENSP00000295208|ensembl:ENSP00000405509|uniprotkb:Q5JPJ3 intact:EBI-2685506|uniprotkb:B4DUA9|uniprotkb:B4DQI6|uniprotkb:E9PD75|ensembl:ENSP00000297071 psi-mi:zn514_human(display_long)|uniprotkb:ZNF514(gene name)|psi-mi:ZNF514(display_short) psi-mi:tra2a_human(display_long)|uniprotkb:Transformer-2 protein homolog A(gene name synonym)|uniprotkb:TRA2A(gene name)|psi-mi:TRA2A(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487117|imex:IM-26985-79 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000144026(gene)|ensembl:ENST00000295208(transcript)|ensembl:ENST00000411425(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|mint:Q96K75|reactome:R-HSA-212436|refseq:NP_001304934.1|refseq:NP_116177.1|refseq:XP_006712869.1 refseq:NP_001269686.1|refseq:NP_001269687.1|refseq:NP_001269688.1|refseq:XP_005249782.1|refseq:NP_037425.1|refseq:XP_016867578.1|refseq:XP_016867579.1|ensembl:ENSG00000164548(gene)|ensembl:ENST00000297071(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:Q13595 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qw27vebM3X0BDC5K6dmpFCHIf8c9606 rogid:JvcdzipB7mCy8eV3z8TaVjucLLM9606 rigid:ReNfR8kesQTfUynorOEdMpZa+RY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96K75 uniprotkb:O75494 intact:EBI-6660752|ensembl:ENSP00000295208|ensembl:ENSP00000405509|uniprotkb:Q5JPJ3 intact:EBI-353655|uniprotkb:Q5JRI3|uniprotkb:Q5JRI4|uniprotkb:A6NFM6|uniprotkb:A6NI42|uniprotkb:A6NIU7|uniprotkb:Q5JRH9|uniprotkb:Q5JRI2|uniprotkb:O60572|uniprotkb:Q96G09|uniprotkb:Q96P17|uniprotkb:Q5JRI0|intact:EBI-11103259|ensembl:ENSP00000420195|uniprotkb:B4DJP9 psi-mi:zn514_human(display_long)|uniprotkb:ZNF514(gene name)|psi-mi:ZNF514(display_short) psi-mi:srs10_human(display_long)|uniprotkb:FUSIP1(gene name synonym)|uniprotkb:TASR(gene name synonym)|uniprotkb:FUS-interacting serine-arginine-rich protein 1(gene name synonym)|uniprotkb:FUSIP2(gene name synonym)|uniprotkb:TLS-associated protein with Ser-Arg repeats(gene name synonym)|uniprotkb:TLS-associated serine-arginine protein(gene name synonym)|uniprotkb:40 kDa SR-repressor protein(gene name synonym)|uniprotkb:SRSF10(gene name)|psi-mi:SRSF10(display_short)|uniprotkb:Splicing factor SRp38(gene name synonym)|uniprotkb:SFRS13A(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 13A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487117|imex:IM-26985-79 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000144026(gene)|ensembl:ENST00000295208(transcript)|ensembl:ENST00000411425(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|mint:Q96K75|reactome:R-HSA-212436|refseq:NP_001304934.1|refseq:NP_116177.1|refseq:XP_006712869.1 refseq:NP_001177936.1|refseq:NP_001177934.1|refseq:NP_001177935.1|refseq:NP_006616.1|refseq:NP_473357.1|ensembl:ENSG00000188529(gene)|ensembl:ENST00000492112(transcript)|go:"GO:0000244"(spliceosomal tri-snRNP complex assembly)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0016482"(cytosolic transport)|go:"GO:0016607"(nuclear speck)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0050733"(RS domain binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034476|interpro:IPR035979|mint:O75494|reactome:R-HSA-72163|refseq:NP_001177938.1 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qw27vebM3X0BDC5K6dmpFCHIf8c9606 rogid:abrRZLYWl3wlG2rHzVZMgej5EWk9606 rigid:ReNfR8kesQTfUynorOEdMpZa+RY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96K75 uniprotkb:Q99873 intact:EBI-6660752|ensembl:ENSP00000295208|ensembl:ENSP00000405509|uniprotkb:Q5JPJ3 intact:EBI-78738|intact:EBI-949313|uniprotkb:A0A087X1W2|uniprotkb:H7C2I1|uniprotkb:Q15529|uniprotkb:Q99872|uniprotkb:Q99874|uniprotkb:Q9NZ04|uniprotkb:Q9NZ05|uniprotkb:Q9NZ06|ensembl:ENSP00000406162|intact:EBI-2622582|uniprotkb:B4E3C3|uniprotkb:G5E9B6|uniprotkb:Q8WUW5|uniprotkb:Q2VP93|uniprotkb:Q6LEU5|intact:EBI-11034520|intact:EBI-6137914 psi-mi:zn514_human(display_long)|uniprotkb:ZNF514(gene name)|psi-mi:ZNF514(display_short) psi-mi:anm1_human(display_long)|uniprotkb:PRMT1(gene name)|psi-mi:PRMT1(display_short)|uniprotkb:Interferon receptor 1-bound protein 4(gene name synonym)|uniprotkb:Histone-arginine N-methyltransferase PRMT1(gene name synonym)|uniprotkb:HMT2(gene name synonym)|uniprotkb:HRMT1L2(gene name synonym)|uniprotkb:IR1B4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487117|imex:IM-26985-79 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000144026(gene)|ensembl:ENST00000295208(transcript)|ensembl:ENST00000411425(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|mint:Q96K75|reactome:R-HSA-212436|refseq:NP_001304934.1|refseq:NP_116177.1|refseq:XP_006712869.1 ensembl:ENSG00000126457(gene)|ensembl:ENST00000454376(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0008170"(N-methyltransferase activity)|go:"GO:0008276"(protein methyltransferase activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008327"(methyl-CpG binding)|go:"GO:0008380"(RNA splicing)|go:"GO:0016274"(protein-arginine N-methyltransferase activity)|go:"GO:0016571"(histone methylation)|go:"GO:0018216"(peptidyl-arginine methylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0034709"(methylosome)|go:"GO:0035241"(protein-arginine omega-N monomethyltransferase activity)|go:"GO:0035242"(protein-arginine omega-N asymmetric methyltransferase activity)|go:"GO:0042054"(histone methyltransferase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043985"(histone H4-R3 methylation)|go:"GO:0044020"("histone methyltransferase activity (H4-R3 specific)")|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045653"(negative regulation of megakaryocyte differentiation)|go:"GO:0046985"(positive regulation of hemoglobin biosynthetic process)|go:"GO:0048273"(mitogen-activated protein kinase p38 binding)|go:"GO:0048738"(cardiac muscle tissue development)|go:"GO:0051260"(protein homooligomerization)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:1904047"(S-adenosyl-L-methionine binding)|interpro:IPR025799|interpro:IPR029063|interpro:IPR041698|mint:Q99873|rcsb pdb:6NT2|reactome:R-HSA-3214858|reactome:R-HSA-6804114|reactome:R-HSA-8936459|reactome:R-HSA-9009391|reactome:R-HSA-9018519|refseq:NP_001527.3|refseq:NP_938074.2|refseq:XP_016882223.1|refseq:XP_016882224.1|refseq:NP_001193971.1|dip:DIP-30878N - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qw27vebM3X0BDC5K6dmpFCHIf8c9606 rogid:8I7isKQC9YJTBzPz1Qve4V8l8Xg9606 rigid:ReNfR8kesQTfUynorOEdMpZa+RY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96K75 uniprotkb:Q14151 intact:EBI-6660752|ensembl:ENSP00000295208|ensembl:ENSP00000405509|uniprotkb:Q5JPJ3 intact:EBI-352869|ensembl:ENSP00000252542|uniprotkb:Q8TB13|uniprotkb:B4DKG3|intact:EBI-2948582 psi-mi:zn514_human(display_long)|uniprotkb:ZNF514(gene name)|psi-mi:ZNF514(display_short) psi-mi:safb2_human(display_long)|uniprotkb:SAFB2(gene name)|psi-mi:SAFB2(display_short)|uniprotkb:KIAA0138(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487117|imex:IM-26985-79 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000144026(gene)|ensembl:ENST00000295208(transcript)|ensembl:ENST00000411425(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|mint:Q96K75|reactome:R-HSA-212436|refseq:NP_001304934.1|refseq:NP_116177.1|refseq:XP_006712869.1 ensembl:ENSG00000130254(gene)|ensembl:ENST00000252542(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016604"(nuclear body)|interpro:IPR035979|go:"GO:0042802"(identical protein binding)|interpro:IPR036361|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043565"(sequence-specific DNA binding)|mint:Q14151|go:"GO:0050684"(regulation of mRNA processing)|go:"GO:0060008"(Sertoli cell differentiation)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003034(DNA-binding SAP)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034782|refseq:NP_055464.1 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qw27vebM3X0BDC5K6dmpFCHIf8c9606 rogid:4/eQxEPzUXIuUuqP2ogEL+zY31g9606 rigid:ReNfR8kesQTfUynorOEdMpZa+RY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96K75 uniprotkb:Q13263 intact:EBI-6660752|ensembl:ENSP00000295208|ensembl:ENSP00000405509|uniprotkb:Q5JPJ3 intact:EBI-78139|uniprotkb:O00677|ensembl:ENSP00000253024|uniprotkb:Q7Z632|uniprotkb:Q93040|uniprotkb:Q96IM1 psi-mi:zn514_human(display_long)|uniprotkb:ZNF514(gene name)|psi-mi:ZNF514(display_short) psi-mi:tif1b_human(display_long)|uniprotkb:TRIM28(gene name)|psi-mi:TRIM28(display_short)|uniprotkb:KAP1(gene name synonym)|uniprotkb:RNF96(gene name synonym)|uniprotkb:TIF1B(gene name synonym)|uniprotkb:Tripartite motif-containing protein 28(gene name synonym)|uniprotkb:Nuclear corepressor KAP-1(gene name synonym)|uniprotkb:KRAB-associated protein 1(gene name synonym)|uniprotkb:KRAB-interacting protein 1(gene name synonym)|uniprotkb:RING finger protein 96(gene name synonym)|uniprotkb:E3 SUMO-protein ligase TRIM28(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TIF1-beta(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487117|imex:IM-26985-79 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000144026(gene)|ensembl:ENST00000295208(transcript)|ensembl:ENST00000411425(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|mint:Q96K75|reactome:R-HSA-212436|refseq:NP_001304934.1|refseq:NP_116177.1|refseq:XP_006712869.1 ensembl:ENSG00000130726(gene)|ensembl:ENST00000253024(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006281"(DNA repair)|go:"GO:0006325"(chromatin organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007566"(embryo implantation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016925"(protein sumoylation)|go:"GO:0019789"(SUMO transferase activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035851"(Krueppel-associated box domain binding)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043045"(DNA methylation involved in embryo development)|go:"GO:0043388"(positive regulation of DNA binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045869"(negative regulation of single stranded viral RNA replication via double stranded DNA intermediate)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0060028"(convergent extension involved in axis elongation)|go:"GO:0060669"(embryonic placenta morphogenesis)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0090309"(positive regulation of DNA methylation-dependent heterochromatin assembly)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|rcsb pdb:6QAJ|rcsb pdb:6QU1|reactome:R-HSA-212436|reactome:R-HSA-3899300|reactome:R-HSA-9609690|go:"GO:1901536"(negative regulation of DNA demethylation)|go:"GO:1902187"|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000653"(regulation of genetic imprinting)|interpro:IPR000315(Zinc finger, B-box)|interpro:IPR001487(Bromodomain)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR003649(B-box, C-terminal)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR036427|interpro:IPR037373|interpro:IPR042713|mint:Q13263|rcsb pdb:1FP0|rcsb pdb:2RO1|rcsb pdb:2YVR|rcsb pdb:6H3A|rcsb pdb:6I9H|refseq:NP_005753.1|dip:DIP-30891N - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qw27vebM3X0BDC5K6dmpFCHIf8c9606 rogid:/yXCDGKUyyYnArOLyfzx6uPR9QY9606 rigid:ReNfR8kesQTfUynorOEdMpZa+RY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96K75 uniprotkb:P06899 intact:EBI-6660752|ensembl:ENSP00000295208|ensembl:ENSP00000405509|uniprotkb:Q5JPJ3 intact:EBI-6150252|uniprotkb:B2R4J4|uniprotkb:O60816|ensembl:ENSP00000342886|ensembl:ENSP00000476136 psi-mi:zn514_human(display_long)|uniprotkb:ZNF514(gene name)|psi-mi:ZNF514(display_short) psi-mi:h2b1j_human(display_long)|uniprotkb:H2BC11(gene name)|psi-mi:H2BC11(display_short)|uniprotkb:H2BFR(gene name synonym)|uniprotkb:HIST1H2BJ(gene name synonym)|uniprotkb:Histone H2B.1(gene name synonym)|uniprotkb:Histone H2B.r(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487117|imex:IM-26985-79 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000144026(gene)|ensembl:ENST00000295208(transcript)|ensembl:ENST00000411425(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|mint:Q96K75|reactome:R-HSA-212436|refseq:NP_001304934.1|refseq:NP_116177.1|refseq:XP_006712869.1 refseq:NP_066402.2|dip:DIP-421N|ensembl:ENSG00000124635(gene)|ensembl:ENST00000339812(transcript)|ensembl:ENST00000607124(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0002227"(innate immune response in mucosa)|go:"GO:0003677"(DNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0010804"(negative regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0019731"(antibacterial humoral response)|go:"GO:0031640"(killing of cells of another organism)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050829"(defense response to Gram-negative bacterium)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0061844"(antimicrobial humoral immune response mediated by antimicrobial peptide)|interpro:IPR000558(Histone H2B)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|mint:P06899|rcsb pdb:2RVQ|rcsb pdb:3A6N|rcsb pdb:3AFA|rcsb pdb:3AN2|rcsb pdb:3AV1|rcsb pdb:3AV2|rcsb pdb:3AYW|rcsb pdb:3AZE|rcsb pdb:3AZF|rcsb pdb:3AZG|rcsb pdb:3AZH|rcsb pdb:3AZI|rcsb pdb:3AZJ|rcsb pdb:3AZK|rcsb pdb:3AZL|rcsb pdb:3AZM|rcsb pdb:3AZN|rcsb pdb:3W96|rcsb pdb:3W97|rcsb pdb:3W98|rcsb pdb:3W99|rcsb pdb:3WAA|rcsb pdb:3WTP|rcsb pdb:4CAY|rcsb pdb:4YM5|rcsb pdb:4YM6|rcsb pdb:4Z5T|rcsb pdb:5AV5|rcsb pdb:5AV6|rcsb pdb:5AV8|rcsb pdb:5AV9|rcsb pdb:5AVB|rcsb pdb:5AVC|rcsb pdb:5AY8|rcsb pdb:5B0Y|rcsb pdb:5B0Z|rcsb pdb:5B24|rcsb pdb:5B2I|rcsb pdb:5B2J|rcsb pdb:5B31|rcsb pdb:5B32|rcsb pdb:5B33|rcsb pdb:5B40|rcsb pdb:5CPI|rcsb pdb:5CPJ|rcsb pdb:5CPK|rcsb pdb:5FUG|rcsb pdb:5GSE|rcsb pdb:5GTC|rcsb pdb:5GXQ|rcsb pdb:5JRG|rcsb pdb:5VEY|rcsb pdb:5X7X|rcsb pdb:5XF3|rcsb pdb:5XF4|rcsb pdb:5XF5|rcsb pdb:5Y0C|rcsb pdb:5Y0D|rcsb pdb:5Z23|rcsb pdb:5Z30|rcsb pdb:5ZBX|rcsb pdb:6A5L|rcsb pdb:6A5O|rcsb pdb:6A5P|rcsb pdb:6A5R|rcsb pdb:6A5T|rcsb pdb:6A5U|rcsb pdb:6BUZ|rcsb pdb:6E0C|rcsb pdb:6E0P|rcsb pdb:6HKT|rcsb pdb:6HTS|rcsb pdb:6INQ|rcsb pdb:6IPU|rcsb pdb:6IQ4|rcsb pdb:6IR9|rcsb pdb:6J4W|rcsb pdb:6J4X|rcsb pdb:6J4Y|rcsb pdb:6J4Z|rcsb pdb:6J50|rcsb pdb:6J51|rcsb pdb:6JOU|rcsb pdb:6JR0|rcsb pdb:6JR1|rcsb pdb:6JXD|rcsb pdb:6K1I|rcsb pdb:6K1J|rcsb pdb:6K1K|rcsb pdb:6KVD|rcsb pdb:6KXV|rcsb pdb:6L49|rcsb pdb:6L4A|rcsb pdb:6L9Z|rcsb pdb:6LA2|rcsb pdb:6LA8|rcsb pdb:6LA9|rcsb pdb:6LAB|rcsb pdb:6LER|rcsb pdb:6M3V|rcsb pdb:6M44|rcsb pdb:6O1D|rcsb pdb:6R8Y|rcsb pdb:6R8Z|rcsb pdb:6R90|rcsb pdb:6R91|rcsb pdb:6R92|rcsb pdb:6R93|rcsb pdb:6R94|rcsb pdb:6T90|rcsb pdb:6T93|rcsb pdb:6USJ|rcsb pdb:6V2K|rcsb pdb:6YOV|rcsb pdb:7BY0|rcsb pdb:7C0M|rcsb pdb:7CCQ|rcsb pdb:7CCR|rcsb pdb:7D1Z|rcsb pdb:7D20|rcsb pdb:7K5X|rcsb pdb:3WA9|rcsb pdb:7K5Y|rcsb pdb:7K60|rcsb pdb:7K61|rcsb pdb:7K63|rcsb pdb:7LYC|reactome:R-HSA-110328|reactome:R-HSA-110329|reactome:R-HSA-110330|reactome:R-HSA-110331|reactome:R-HSA-1221632|reactome:R-HSA-171306|reactome:R-HSA-1912408|reactome:R-HSA-201722|reactome:R-HSA-212300|reactome:R-HSA-2299718|reactome:R-HSA-2559580|reactome:R-HSA-2559582|reactome:R-HSA-2559586|reactome:R-HSA-3214815|reactome:R-HSA-3214847|reactome:R-HSA-427359|reactome:R-HSA-427389|reactome:R-HSA-427413|reactome:R-HSA-5250924|reactome:R-HSA-5334118|reactome:R-HSA-5578749|reactome:R-HSA-5617472|reactome:R-HSA-5625886|reactome:R-HSA-5689880|reactome:R-HSA-5693565|reactome:R-HSA-5693571|reactome:R-HSA-5693607|reactome:R-HSA-606279|reactome:R-HSA-69473|reactome:R-HSA-73728|reactome:R-HSA-73772|reactome:R-HSA-8866654|reactome:R-HSA-8936459|reactome:R-HSA-8939236|reactome:R-HSA-9018519|reactome:R-HSA-912446|reactome:R-HSA-9609690|reactome:R-HSA-9610379|reactome:R-HSA-9616222|reactome:R-HSA-9670095|reactome:R-HSA-9710421|reactome:R-HSA-977225 - - comment:"author score: 15" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qw27vebM3X0BDC5K6dmpFCHIf8c9606 rogid:74GQlSjGG1Ez6Uog74VXPLryKBc9606 rigid:ReNfR8kesQTfUynorOEdMpZa+RY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96K75 uniprotkb:P04637 intact:EBI-6660752|ensembl:ENSP00000295208|ensembl:ENSP00000405509|uniprotkb:Q5JPJ3 intact:EBI-366083|uniprotkb:Q15086|uniprotkb:Q15087|uniprotkb:Q15088|uniprotkb:Q16535|uniprotkb:Q16807|uniprotkb:Q16808|uniprotkb:Q16809|uniprotkb:Q16810|uniprotkb:Q16811|uniprotkb:Q16848|uniprotkb:Q86UG1|uniprotkb:Q8J016|uniprotkb:Q99659|uniprotkb:Q9BTM4|uniprotkb:Q9HAQ8|uniprotkb:Q9NP68|uniprotkb:Q9NPJ2|uniprotkb:Q9NZD0|uniprotkb:Q9UBI2|uniprotkb:Q9UQ61|ensembl:ENSP00000269305|ensembl:ENSP00000391478|intact:EBI-28980681|uniprotkb:Q2XN98|uniprotkb:Q3LRW1|uniprotkb:Q3LRW2|uniprotkb:Q3LRW3|uniprotkb:Q3LRW4|uniprotkb:Q3LRW5 psi-mi:zn514_human(display_long)|uniprotkb:ZNF514(gene name)|psi-mi:ZNF514(display_short) psi-mi:p53_human(display_long)|uniprotkb:TP53(gene name)|psi-mi:TP53(display_short)|uniprotkb:P53(gene name synonym)|uniprotkb:Tumor suppressor p53(gene name synonym)|uniprotkb:Phosphoprotein p53(gene name synonym)|uniprotkb:Antigen NY-CO-13(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487117|imex:IM-26985-79 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000144026(gene)|ensembl:ENST00000295208(transcript)|ensembl:ENST00000411425(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|mint:Q96K75|reactome:R-HSA-212436|refseq:NP_001304934.1|refseq:NP_116177.1|refseq:XP_006712869.1 refseq:NP_001263624.1|refseq:NP_001263625.1|ensembl:ENSG00000141510(gene)|ensembl:ENST00000269305(transcript)|ensembl:ENST00000445888(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0000987"(cis-regulatory region sequence-specific DNA binding)|go:"GO:0001046"(core promoter sequence-specific DNA binding)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0001216"(DNA-binding transcription activator activity)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001756"(somitogenesis)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0002020"(protease binding)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0002360"(T cell lineage commitment)|go:"GO:0002326"(B cell lineage commitment)|go:"GO:0031497"(chromatin assembly)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034103"(regulation of tissue remodeling)|go:"GO:0034613"(cellular protein localization)|go:"GO:0034644"(cellular response to UV)|go:"GO:0035033"(histone deacetylase regulator activity)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0035690"|go:"GO:0035794"(positive regulation of mitochondrial membrane permeability)|go:"GO:0035861"(site of double-strand break)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0036310"(ATP-dependent DNA/DNA annealing activity)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042771"(intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0002931"(response to ischemia)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006914"(autophagy)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0006977"(DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest)|go:"GO:0006978"(DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator)|go:"GO:0006983"(ER overload response)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007369"(gastrulation)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0043153"(entrainment of circadian clock by photoperiod)|go:"GO:0043504"(mitochondrial DNA repair)|go:"GO:0043516"(regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0043621"(protein self-association)|go:"GO:0045861"(negative regulation of proteolysis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045899"(positive regulation of RNA polymerase II transcription preinitiation complex assembly)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048512"(circadian behavior)|go:"GO:0048539"(bone marrow development)|go:"GO:0048568"(embryonic organ development)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0051097"(negative regulation of helicase activity)|go:"GO:0051262"(protein tetramerization)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060218"(hematopoietic stem cell differentiation)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0062100"(positive regulation of programmed necrotic cell death)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070245"(positive regulation of thymocyte apoptotic process)|go:"GO:0070266"(necroptotic process)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0071494"(cellular response to UV-C)|go:"GO:0072331"(signal transduction by p53 class mediator)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0072717"(cellular response to actinomycin D)|go:"GO:0090200"(positive regulation of release of cytochrome c from mitochondria)|go:"GO:0090343"(positive regulation of cell aging)|go:"GO:0090399"(replicative senescence)|go:"GO:0090403"(oxidative stress-induced premature senescence)|go:"GO:0097193"(intrinsic apoptotic signaling pathway)|go:"GO:0097252"(oligodendrocyte apoptotic process)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140296"(general transcription initiation factor binding)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1901525"(negative regulation of mitophagy)|go:"GO:1902108"(regulation of mitochondrial membrane permeability involved in apoptotic process)|go:"GO:1902253"(regulation of intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1902895"(positive regulation of miRNA transcription)|go:"GO:1903799"(negative regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1904024"(negative regulation of glucose catabolic process to lactate via pyruvate)|go:"GO:1905856"(negative regulation of pentose-phosphate shunt)|go:"GO:1990144"(intrinsic apoptotic signaling pathway in response to hypoxia)|go:"GO:1990248"(regulation of transcription from RNA polymerase II promoter in response to DNA damage)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:2000269"(regulation of fibroblast apoptotic process)|go:"GO:2000378"(negative regulation of reactive oxygen species metabolic process)|go:"GO:2000379"(positive regulation of reactive oxygen species metabolic process)|go:"GO:2000772"(regulation of cellular senescence)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR002117(p53 tumor antigen)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR010991(p53, tetramerisation)|interpro:IPR011615(p53, DNA-binding)|go:"GO:0007569"(cell aging)|go:"GO:0008104"(protein localization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008340"(determination of adult lifespan)|go:"GO:0009299"(mRNA transcription)|go:"GO:0009303"(rRNA transcription)|go:"GO:0009651"(response to salt stress)|go:"GO:0010165"(response to X-ray)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010666"(positive regulation of cardiac muscle cell apoptotic process)|go:"GO:0016032"(viral process)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016605"(PML body)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021549"(cerebellum development)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031065"(positive regulation of histone deacetylation)|interpro:IPR012346(p53 and RUNT-type transcription factor, DNA-binding)|interpro:IPR013872("p53 transactivation domain (TAD)")|interpro:IPR036674|interpro:IPR040926|rcsb pdb:2ATA|rcsb pdb:2B3G|rcsb pdb:2BIM|rcsb pdb:2BIN|rcsb pdb:2BIO|rcsb pdb:2BIP|rcsb pdb:2AHI|rcsb pdb:2BIQ|rcsb pdb:2F1X|rcsb pdb:2FEJ|rcsb pdb:2FOJ|rcsb pdb:2FOO|rcsb pdb:2GS0|rcsb pdb:2H1L|rcsb pdb:2H2D|rcsb pdb:2H2F|rcsb pdb:2H4F|rcsb pdb:2H4H|rcsb pdb:2H4J|rcsb pdb:2H59|rcsb pdb:2J0Z|rcsb pdb:2J10|rcsb pdb:2J11|rcsb pdb:2J1W|rcsb pdb:2J1X|rcsb pdb:2J1Y|rcsb pdb:2J1Z|rcsb pdb:2J20|rcsb pdb:2J21|rcsb pdb:2K8F|rcsb pdb:2L14|rcsb pdb:2LY4|rcsb pdb:2MEJ|rcsb pdb:2MWO|rcsb pdb:2MWP|rcsb pdb:2MWY|rcsb pdb:2MZD|rcsb pdb:2OCJ|rcsb pdb:2PCX|rcsb pdb:1A1U|rcsb pdb:1AIE|rcsb pdb:1C26|rcsb pdb:1DT7|rcsb pdb:1GZH|rcsb pdb:1H26|rcsb pdb:1HS5|rcsb pdb:1JSP|rcsb pdb:1KZY|rcsb pdb:1MA3|rcsb pdb:1OLG|rcsb pdb:1OLH|rcsb pdb:1PES|rcsb pdb:1PET|mint:P04637|rcsb pdb:1SAE|rcsb pdb:1SAF|rcsb pdb:1SAK|rcsb pdb:1SAL|rcsb pdb:1TSR|rcsb pdb:1TUP|rcsb pdb:1UOL|rcsb pdb:1XQH|rcsb pdb:1YC5|rcsb pdb:1YCQ|rcsb pdb:1YCR|rcsb pdb:1YCS|rcsb pdb:2AC0|rcsb pdb:2ADY|refseq:NP_000537.3|refseq:NP_001119584.1|refseq:NP_001119585.1|refseq:NP_001119586.1|refseq:NP_001119587.1|refseq:NP_001119588.1|refseq:NP_001119589.1|rcsb pdb:2RUK|rcsb pdb:2VUK|rcsb pdb:3Q06|rcsb pdb:2WGX|rcsb pdb:2X0U|rcsb pdb:2X0V|rcsb pdb:2X0W|rcsb pdb:2XWR|rcsb pdb:2YBG|rcsb pdb:2YDR|rcsb pdb:2Z5S|rcsb pdb:2Z5T|rcsb pdb:3SAK|rcsb pdb:3D05|rcsb pdb:3D06|rcsb pdb:3D07|rcsb pdb:3D08|rcsb pdb:3D09|rcsb pdb:3D0A|rcsb pdb:3DAB|rcsb pdb:3DAC|rcsb pdb:3IGK|rcsb pdb:3IGL|rcsb pdb:3KMD|rcsb pdb:3TG5|rcsb pdb:3KZ8|rcsb pdb:3LW1|rcsb pdb:3OQ5|rcsb pdb:3PDH|rcsb pdb:3Q01|rcsb pdb:3Q05|rcsb pdb:3TS8|rcsb pdb:3ZME|rcsb pdb:4AGM|rcsb pdb:4AGN|rcsb pdb:4AGO|rcsb pdb:4AGP|rcsb pdb:4AGQ|rcsb pdb:4BUZ|rcsb pdb:4BV2|rcsb pdb:4HFZ|rcsb pdb:4HJE|rcsb pdb:4IBQ|rcsb pdb:4IBS|rcsb pdb:4IBT|rcsb pdb:4IBU|rcsb pdb:4IBV|rcsb pdb:4IBW|rcsb pdb:4IBY|rcsb pdb:4IBZ|rcsb pdb:4IJT|rcsb pdb:4KVP|rcsb pdb:4LO9|rcsb pdb:4LOE|rcsb pdb:4LOF|rcsb pdb:4MZI|rcsb pdb:4MZR|rcsb pdb:4QO1|rcsb pdb:4RP6|rcsb pdb:4RP7|rcsb pdb:4X34|rcsb pdb:4XR8|rcsb pdb:4ZZJ|rcsb pdb:5A7B|rcsb pdb:5AB9|rcsb pdb:5ABA|rcsb pdb:4AGL|rcsb pdb:5AOI|rcsb pdb:5AOJ|rcsb pdb:5AOK|rcsb pdb:5AOL|rcsb pdb:5AOM|rcsb pdb:6XRE|rcsb pdb:7BWN|rcsb pdb:7DHY|rcsb pdb:7DHZ|rcsb pdb:7EL4|reactome:R-HSA-111448|reactome:R-HSA-139915|reactome:R-HSA-1912408|reactome:R-HSA-2559580|reactome:R-HSA-2559584|reactome:R-HSA-2559585|reactome:R-HSA-2559586|reactome:R-HSA-3232118|reactome:R-HSA-349425|reactome:R-HSA-390471|reactome:R-HSA-5620971|reactome:R-HSA-5628897|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-5693565|reactome:R-HSA-6785807|reactome:R-HSA-6796648|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803207|reactome:R-HSA-6803211|reactome:R-HSA-6804114|reactome:R-HSA-6804115|reactome:R-HSA-6804116|reactome:R-HSA-6804754|reactome:R-HSA-6804756|reactome:R-HSA-6804757|reactome:R-HSA-6804758|reactome:R-HSA-6804759|reactome:R-HSA-6804760|reactome:R-HSA-6811555|reactome:R-HSA-69473|reactome:R-HSA-69481|reactome:R-HSA-69541|reactome:R-HSA-69895|reactome:R-HSA-8852276|reactome:R-HSA-8853884|reactome:R-HSA-8941855|reactome:R-HSA-8943724|reactome:R-HSA-983231|rcsb pdb:5ECG|rcsb pdb:5G4M|rcsb pdb:5G4N|rcsb pdb:5BUA|rcsb pdb:5G4O|rcsb pdb:5HOU|rcsb pdb:5HP0|rcsb pdb:5HPD|rcsb pdb:5LAP|rcsb pdb:5LGY|rcsb pdb:5MCT|rcsb pdb:5MCU|rcsb pdb:5MCV|rcsb pdb:5MCW|rcsb pdb:5MF7|rcsb pdb:5MG7|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5O1A|rcsb pdb:5O1B|rcsb pdb:5O1C|rcsb pdb:5O1D|rcsb pdb:5O1E|rcsb pdb:5O1F|rcsb pdb:5O1G|rcsb pdb:5O1H|rcsb pdb:5O1I|rcsb pdb:5OL0|rcsb pdb:5UN8|rcsb pdb:5XZC|rcsb pdb:6FF9|rcsb pdb:6FJ5|rcsb pdb:6GGA|rcsb pdb:6GGB|rcsb pdb:6GGC|rcsb pdb:6GGD|rcsb pdb:6GGE|rcsb pdb:6GGF|rcsb pdb:6LHD|rcsb pdb:6R5L|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:6RWS|rcsb pdb:6RWU|rcsb pdb:6RX2|rcsb pdb:6RZ3|rcsb pdb:6S39|rcsb pdb:6S40|rcsb pdb:6S9Q|rcsb pdb:6SHZ|rcsb pdb:6SI0|rcsb pdb:6SI1|rcsb pdb:6SI2|rcsb pdb:6SI3|rcsb pdb:6SI4|rcsb pdb:6SIN|rcsb pdb:6SIO|rcsb pdb:6SIP|rcsb pdb:6SIQ|rcsb pdb:6SL6|rcsb pdb:6SLV|rcsb pdb:6T58|rcsb pdb:6V4F|rcsb pdb:6V4H|rcsb pdb:6VQO|rcsb pdb:6VR1|rcsb pdb:6VR5|rcsb pdb:6VRM|rcsb pdb:6VRN|rcsb pdb:6W51|rcsb pdb:6S3C|ensembl:ENSP00000269305|ensembl:ENST00000420246|ensembl:ENSP00000391127|ensembl:ENSP00000391478|ensembl:ENST00000455263|ensembl:ENSP00000398846|ensembl:ENST00000504290|ensembl:ENSP00000484409|ensembl:ENST00000504937|ensembl:ENSP00000481179|ensembl:ENST00000510385|ensembl:ENSP00000478499|ensembl:ENST00000610292|ensembl:ENSP00000478219|ensembl:ENST00000610538|ensembl:ENSP00000480868|ensembl:ENST00000619485|ensembl:ENSP00000482537|ensembl:ENST00000620739|ensembl:ENSP00000481638|ensembl:ENST00000622645|ensembl:ENSP00000482222|refseq:NP_001119590.1|refseq:NP_001263626.1|refseq:NP_001263627.1|refseq:NP_001263628.1|refseq:NP_001263689.1|refseq:NP_001263690.1|dip:DIP-368N - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qw27vebM3X0BDC5K6dmpFCHIf8c9606 rogid:fGN3kSCGIpi/D6d/X5kaB0Xu8/k9606 rigid:ReNfR8kesQTfUynorOEdMpZa+RY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96K75 uniprotkb:P62995 intact:EBI-6660752|ensembl:ENSP00000295208|ensembl:ENSP00000405509|uniprotkb:Q5JPJ3 intact:EBI-725485|uniprotkb:O15449|uniprotkb:Q15815|uniprotkb:Q64283|uniprotkb:B4DVK2|uniprotkb:D3DNU3|ensembl:ENSP00000416959 psi-mi:zn514_human(display_long)|uniprotkb:ZNF514(gene name)|psi-mi:ZNF514(display_short) psi-mi:tra2b_human(display_long)|uniprotkb:TRA2B(gene name)|psi-mi:TRA2B(display_short)|uniprotkb:SFRS10(gene name synonym)|uniprotkb:Transformer-2 protein homolog B(gene name synonym)|uniprotkb:Splicing factor, arginine/serine-rich 10(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487117|imex:IM-26985-79 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000144026(gene)|ensembl:ENST00000295208(transcript)|ensembl:ENST00000411425(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|mint:Q96K75|reactome:R-HSA-212436|refseq:NP_001304934.1|refseq:NP_116177.1|refseq:XP_006712869.1 refseq:NP_004584.1|refseq:XP_005247760.1|refseq:NP_001230808.1|refseq:XP_011511374.1|ensembl:ENSG00000136527(gene)|ensembl:ENST00000453386(transcript)|go:"GO:0000302"(response to reactive oxygen species)|go:"GO:0000375"(RNA splicing, via transesterification reactions)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021796"(cerebral cortex regionalization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:1990403"(embryonic brain development)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR035979|mint:P62995|rcsb pdb:2CQC|rcsb pdb:2KXN|rcsb pdb:2RRA|rcsb pdb:2RRB|reactome:R-HSA-72163|reactome:R-HSA-9013418|reactome:R-HSA-9013422|refseq:XP_016862522.1|dip:DIP-42278N - - comment:"author score: 23" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qw27vebM3X0BDC5K6dmpFCHIf8c9606 rogid:6uZGeHEDlIVsb2uPeo+9NoR4tDw9606 rigid:ReNfR8kesQTfUynorOEdMpZa+RY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96K75 uniprotkb:Q96DG6 intact:EBI-6660752|ensembl:ENSP00000295208|ensembl:ENSP00000405509|uniprotkb:Q5JPJ3 intact:EBI-1044268|uniprotkb:Q8TED6|uniprotkb:D3DTC7|ensembl:ENSP00000296658 psi-mi:zn514_human(display_long)|uniprotkb:ZNF514(gene name)|psi-mi:ZNF514(display_short) psi-mi:cmbl_human(display_long)|uniprotkb:CMBL(gene name)|psi-mi:CMBL(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487117|imex:IM-26985-79 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000144026(gene)|ensembl:ENST00000295208(transcript)|ensembl:ENST00000411425(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|mint:Q96K75|reactome:R-HSA-212436|refseq:NP_001304934.1|refseq:NP_116177.1|refseq:XP_006712869.1 refseq:NP_620164.1|ensembl:ENSG00000164237(gene)|ensembl:ENST00000296658(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0006805"(xenobiotic metabolic process)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002925(Dienelactone hydrolase)|interpro:IPR029058|interpro:IPR042946|mint:Q96DG6|reactome:R-HSA-211945|refseq:XP_016864523.1|refseq:XP_016864524.1 - - comment:"author score: 24" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qw27vebM3X0BDC5K6dmpFCHIf8c9606 rogid:nIOgS/jTgYbRXndPjCCMtqb0cHU9606 rigid:ReNfR8kesQTfUynorOEdMpZa+RY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96K75 uniprotkb:P67809 intact:EBI-6660752|ensembl:ENSP00000295208|ensembl:ENSP00000405509|uniprotkb:Q5JPJ3 intact:EBI-354065|uniprotkb:P16990|uniprotkb:P16991|uniprotkb:Q14972|uniprotkb:Q15325|uniprotkb:Q5FVF0|ensembl:ENSP00000361626 psi-mi:zn514_human(display_long)|uniprotkb:ZNF514(gene name)|psi-mi:ZNF514(display_short) psi-mi:ybox1_human(display_long)|uniprotkb:YBX1(gene name)|psi-mi:YBX1(display_short)|uniprotkb:YB1(gene name synonym)|uniprotkb:NSEP1(gene name synonym)|uniprotkb:Y-box transcription factor(gene name synonym)|uniprotkb:CCAAT-binding transcription factor I subunit A(gene name synonym)|uniprotkb:Enhancer factor I subunit A(gene name synonym)|uniprotkb:DNA-binding protein B(gene name synonym)|uniprotkb:Nuclease-sensitive element-binding protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487117|imex:IM-26985-79 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000144026(gene)|ensembl:ENST00000295208(transcript)|ensembl:ENST00000411425(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|mint:Q96K75|reactome:R-HSA-212436|refseq:NP_001304934.1|refseq:NP_116177.1|refseq:XP_006712869.1 refseq:NP_004550.2|dip:DIP-29405N|go:"GO:0070934"(CRD-mediated mRNA stabilization)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0071204"(histone pre-mRNA 3'end processing complex)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990124"(messenger ribonucleoprotein complex)|go:"GO:1990428"(miRNA transport)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000773"(negative regulation of cellular senescence)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR019844|mint:P67809|rcsb pdb:1H95|rcsb pdb:5YTS|rcsb pdb:5YTT|rcsb pdb:5YTV|rcsb pdb:5YTX|rcsb pdb:6A6L|rcsb pdb:6KTC|rcsb pdb:6KUG|rcsb pdb:6LMR|rcsb pdb:6LMS|reactome:R-HSA-72163|reactome:R-HSA-72165|reactome:R-HSA-9017802|ensembl:ENSG00000065978(gene)|ensembl:ENST00000321358(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005689"(U12-type spliceosomal complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006397"(mRNA processing)|go:"GO:0008380"(RNA splicing)|go:"GO:0008544"(epidermis development)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035198"(miRNA binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0048598"(embryonic morphogenesis)|go:"GO:0050658"(RNA transport)|go:"GO:0051020"(GTPase binding)|go:"GO:0051031"(tRNA transport)|go:"GO:0051154"(negative regulation of striated muscle cell differentiation)|go:"GO:0051781"(positive regulation of cell division)|go:"GO:0062153"(C5-methylcytidine-containing RNA binding) - - comment:"author score: 27" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qw27vebM3X0BDC5K6dmpFCHIf8c9606 rogid:0/mAXOzokPlDByFFzGTP8bp9nqo9606 rigid:ReNfR8kesQTfUynorOEdMpZa+RY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96K75 uniprotkb:P13807 intact:EBI-6660752|ensembl:ENSP00000295208|ensembl:ENSP00000405509|uniprotkb:Q5JPJ3 intact:EBI-740553|intact:EBI-963094|intact:EBI-2948518|uniprotkb:Q9BTT9|ensembl:ENSP00000317904 psi-mi:zn514_human(display_long)|uniprotkb:ZNF514(gene name)|psi-mi:ZNF514(display_short) psi-mi:gys1_human(display_long)|uniprotkb:GYS1(gene name)|psi-mi:GYS1(display_short)|uniprotkb:GYS(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487117|imex:IM-26985-79 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000144026(gene)|ensembl:ENST00000295208(transcript)|ensembl:ENST00000411425(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001909(Krueppel-associated box)|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR036051|interpro:IPR036236|mint:Q96K75|reactome:R-HSA-212436|refseq:NP_001304934.1|refseq:NP_116177.1|refseq:XP_006712869.1 refseq:NP_001155059.1|refseq:NP_002094.2|ensembl:ENSG00000104812(gene)|ensembl:ENST00000323798(transcript)|go:"GO:0004373"("glycogen (starch) synthase activity")|go:"GO:0005536"(glucose binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005978"(glycogen biosynthetic process)|go:"GO:0007507"(heart development)|go:"GO:0016020"(membrane)|go:"GO:0016234"(inclusion body)|go:"GO:0019901"(protein kinase binding)|go:"GO:0061547"(glycogen synthase activity, transferring glucose-1-phosphate)|interpro:IPR008631(Glycogen synthase)|mint:P13807|reactome:R-HSA-3322077|reactome:R-HSA-3785653|reactome:R-HSA-3814836|reactome:R-HSA-3828062 - - comment:"author score: 32" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:qw27vebM3X0BDC5K6dmpFCHIf8c9606 rogid:qJ6wzje5P3wnfVq0oaFQqhAIQ1Q9606 rigid:ReNfR8kesQTfUynorOEdMpZa+RY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15326 uniprotkb:Q9NV06 intact:EBI-2623509|intact:EBI-28967957|ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENSP00000381053|intact:EBI-2799565|uniprotkb:B2R6G8|uniprotkb:B7Z293|uniprotkb:F6UH50|uniprotkb:Q2LD45|uniprotkb:Q2LD46|uniprotkb:Q2LD47|uniprotkb:Q2LD48|uniprotkb:Q5VUI1|uniprotkb:Q8N4B3 intact:EBI-7402939|uniprotkb:Q3MII9|uniprotkb:Q96JY7|uniprotkb:Q9NZX3|intact:MINT-4994304|uniprotkb:Q8NCH8|uniprotkb:Q8TC51|ensembl:ENSP00000484962 psi-mi:zmy11_human(display_long)|uniprotkb:BRAM1(gene name synonym)|uniprotkb:Bone morphogenetic protein receptor-associated molecule 1(gene name synonym)|uniprotkb:ZMYND11(gene name)|psi-mi:ZMYND11(display_short)|uniprotkb:Adenovirus 5 E1A-binding protein(gene name synonym)|uniprotkb:BS69(gene name synonym)|uniprotkb:Protein BS69(gene name synonym) psi-mi:dca13_human(display_long)|uniprotkb:HSPC064(orf name)|uniprotkb:DCAF13(gene name)|psi-mi:DCAF13(display_short)|uniprotkb:WDSOF1(gene name synonym)|uniprotkb:WD repeat and SOF domain-containing protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487078|imex:IM-26985-459 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENST00000381607|ensembl:ENSP00000371020|ensembl:ENST00000397959|ensembl:ENSP00000381050|ensembl:ENSP00000381053|ensembl:ENST00000509513|ensembl:ENSP00000424205|ensembl:ENST00000558098|ensembl:ENSP00000452959|ensembl:ENST00000602682|ensembl:ENSP00000473321|refseq:NP_001189396.1|refseq:NP_001189397.1|refseq:XP_016871076.1|refseq:XP_016871077.1|refseq:XP_016871078.1|refseq:XP_016871079.1|refseq:XP_016871081.1|refseq:XP_016871082.1|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0051607"(defense response to virus)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR035505|interpro:IPR036427|mint:Q15326|rcsb pdb:4NS5|rcsb pdb:5HDA|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000015171(gene)|ensembl:ENST00000381591(transcript)|ensembl:ENST00000381604(transcript)|ensembl:ENST00000397962(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:XP_005252416.1|refseq:NP_001189393.1|refseq:NP_001189394.1|refseq:NP_006615.2|refseq:NP_997644.2|refseq:XP_005252418.1|refseq:XP_005252419.1|refseq:XP_006717439.1 refseq:NP_056235.4|ensembl:ENSG00000164934(gene)|ensembl:ENST00000612750(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030054"(cell junction)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0032040"(small-subunit processome)|go:"GO:0080008"(Cul4-RING E3 ubiquitin ligase complex)|interpro:IPR001680(WD40 repeat)|interpro:IPR007287(Sof1-like protein)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR036322|mint:Q9NV06|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-8951664 - - comment:mint|comment:homomint|function:Possible role in ribosomal RNA processing|comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/QjUI+SjkfyB3GDHo7s09Sy1l4o9606 rogid:Ep2z6/V6/US0sXDqjqjpVqmf/zM9606 rigid:tgko+3sqcr3EX5ffvHMsShck6KY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15326 uniprotkb:Q02930 intact:EBI-2623509|intact:EBI-28967957|ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENSP00000381053|intact:EBI-2799565|uniprotkb:B2R6G8|uniprotkb:B7Z293|uniprotkb:F6UH50|uniprotkb:Q2LD45|uniprotkb:Q2LD46|uniprotkb:Q2LD47|uniprotkb:Q2LD48|uniprotkb:Q5VUI1|uniprotkb:Q8N4B3 intact:EBI-8636872|ensembl:ENSP00000350359|uniprotkb:Q75N02|uniprotkb:A8KA51|uniprotkb:Q86UJ9|uniprotkb:B5BUH3|uniprotkb:Q06246|intact:MINT-8162615|intact:MINT-267970|uniprotkb:B4DU13|uniprotkb:Q05886|uniprotkb:C9JK47 psi-mi:zmy11_human(display_long)|uniprotkb:BRAM1(gene name synonym)|uniprotkb:Bone morphogenetic protein receptor-associated molecule 1(gene name synonym)|uniprotkb:ZMYND11(gene name)|psi-mi:ZMYND11(display_short)|uniprotkb:Adenovirus 5 E1A-binding protein(gene name synonym)|uniprotkb:BS69(gene name synonym)|uniprotkb:Protein BS69(gene name synonym) psi-mi:creb5_human(display_long)|uniprotkb:CREB5(gene name)|psi-mi:CREB5(display_short)|uniprotkb:CREBPA(gene name synonym)|uniprotkb:cAMP-response element-binding protein A(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487078|imex:IM-26985-459 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENST00000381607|ensembl:ENSP00000371020|ensembl:ENST00000397959|ensembl:ENSP00000381050|ensembl:ENSP00000381053|ensembl:ENST00000509513|ensembl:ENSP00000424205|ensembl:ENST00000558098|ensembl:ENSP00000452959|ensembl:ENST00000602682|ensembl:ENSP00000473321|refseq:NP_001189396.1|refseq:NP_001189397.1|refseq:XP_016871076.1|refseq:XP_016871077.1|refseq:XP_016871078.1|refseq:XP_016871079.1|refseq:XP_016871081.1|refseq:XP_016871082.1|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0051607"(defense response to virus)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR035505|interpro:IPR036427|mint:Q15326|rcsb pdb:4NS5|rcsb pdb:5HDA|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000015171(gene)|ensembl:ENST00000381591(transcript)|ensembl:ENST00000381604(transcript)|ensembl:ENST00000397962(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:XP_005252416.1|refseq:NP_001189393.1|refseq:NP_001189394.1|refseq:NP_006615.2|refseq:NP_997644.2|refseq:XP_005252418.1|refseq:XP_005252419.1|refseq:XP_006717439.1 ensembl:ENST00000357727(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0035497"(cAMP response element binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990837"(sequence-specific double-stranded DNA binding)|interpro:IPR004827("Basic-leucine zipper (bZIP) transcription factor")|interpro:IPR013087(Zinc finger, C2H2-type/integrase, DNA-binding)|interpro:IPR016378(Transcription factor, cyclic AMP-dependent)|interpro:IPR036236|mint:Q02930|ensembl:ENSG00000146592(gene)|refseq:XP_005249963.1|refseq:NP_004895.2|refseq:NP_878901.2|refseq:NP_001011666.1|refseq:NP_878902.2|refseq:XP_016868295.1|refseq:XP_016868297.1 - - function:Binds to the cAMP response element and activates transcription|comment:"author score: 16" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/QjUI+SjkfyB3GDHo7s09Sy1l4o9606 rogid:v27tGFZeHt18Q8QzT+d8txg6Fhc9606 rigid:tgko+3sqcr3EX5ffvHMsShck6KY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15326 uniprotkb:Q6UXN9 intact:EBI-2623509|intact:EBI-28967957|ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENSP00000381053|intact:EBI-2799565|uniprotkb:B2R6G8|uniprotkb:B7Z293|uniprotkb:F6UH50|uniprotkb:Q2LD45|uniprotkb:Q2LD46|uniprotkb:Q2LD47|uniprotkb:Q2LD48|uniprotkb:Q5VUI1|uniprotkb:Q8N4B3 intact:EBI-1176082|uniprotkb:Q8TEB2|uniprotkb:A8K5R5|intact:EBI-2562464|ensembl:ENSP00000296490 psi-mi:zmy11_human(display_long)|uniprotkb:BRAM1(gene name synonym)|uniprotkb:Bone morphogenetic protein receptor-associated molecule 1(gene name synonym)|uniprotkb:ZMYND11(gene name)|psi-mi:ZMYND11(display_short)|uniprotkb:Adenovirus 5 E1A-binding protein(gene name synonym)|uniprotkb:BS69(gene name synonym)|uniprotkb:Protein BS69(gene name synonym) psi-mi:wdr82_human(display_long)|uniprotkb:Protein TMEM113(gene name synonym)|uniprotkb:TMEM113(gene name synonym)|uniprotkb:WDR82(gene name)|psi-mi:WDR82(display_short)|uniprotkb:Swd2(gene name synonym)|uniprotkb:WDR82A(gene name synonym)|uniprotkb:UNQ9342/PRO34047(orf name) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487078|imex:IM-26985-459 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENST00000381607|ensembl:ENSP00000371020|ensembl:ENST00000397959|ensembl:ENSP00000381050|ensembl:ENSP00000381053|ensembl:ENST00000509513|ensembl:ENSP00000424205|ensembl:ENST00000558098|ensembl:ENSP00000452959|ensembl:ENST00000602682|ensembl:ENSP00000473321|refseq:NP_001189396.1|refseq:NP_001189397.1|refseq:XP_016871076.1|refseq:XP_016871077.1|refseq:XP_016871078.1|refseq:XP_016871079.1|refseq:XP_016871081.1|refseq:XP_016871082.1|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0051607"(defense response to virus)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR035505|interpro:IPR036427|mint:Q15326|rcsb pdb:4NS5|rcsb pdb:5HDA|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000015171(gene)|ensembl:ENST00000381591(transcript)|ensembl:ENST00000381604(transcript)|ensembl:ENST00000397962(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:XP_005252416.1|refseq:NP_001189393.1|refseq:NP_001189394.1|refseq:NP_006615.2|refseq:NP_997644.2|refseq:XP_005252418.1|refseq:XP_005252419.1|refseq:XP_006717439.1 refseq:NP_079498.2|ensembl:ENSG00000164091(gene)|ensembl:ENST00000296490(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005730"(nucleolus)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0051568"(histone H3-K4 methylation)|go:"GO:0072357"(PTW/PP1 phosphatase complex)|go:"GO:0080182"(histone H3-K4 trimethylation)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR020472|interpro:IPR036322|interpro:IPR037867|mint:Q6UXN9 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/QjUI+SjkfyB3GDHo7s09Sy1l4o9606 rogid:0TyKYwpTLd22Cm+ihT1+n0oo12c9606 rigid:tgko+3sqcr3EX5ffvHMsShck6KY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15326 uniprotkb:P47914 intact:EBI-2623509|intact:EBI-28967957|ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENSP00000381053|intact:EBI-2799565|uniprotkb:B2R6G8|uniprotkb:B7Z293|uniprotkb:F6UH50|uniprotkb:Q2LD45|uniprotkb:Q2LD46|uniprotkb:Q2LD47|uniprotkb:Q2LD48|uniprotkb:Q5VUI1|uniprotkb:Q8N4B3 intact:EBI-714039|uniprotkb:Q6IPY3|ensembl:ENSP00000418346|ensembl:ENSP00000418868|ensembl:ENSP00000420673|ensembl:ENSP00000294189|ensembl:ENSP00000417048|ensembl:ENSP00000418153|uniprotkb:B2R4M8|uniprotkb:A8K0H3 psi-mi:zmy11_human(display_long)|uniprotkb:BRAM1(gene name synonym)|uniprotkb:Bone morphogenetic protein receptor-associated molecule 1(gene name synonym)|uniprotkb:ZMYND11(gene name)|psi-mi:ZMYND11(display_short)|uniprotkb:Adenovirus 5 E1A-binding protein(gene name synonym)|uniprotkb:BS69(gene name synonym)|uniprotkb:Protein BS69(gene name synonym) psi-mi:rl29_human(display_long)|uniprotkb:Cell surface heparin-binding protein HIP(gene name synonym)|uniprotkb:RPL29(gene name)|psi-mi:RPL29(display_short)|uniprotkb:Large ribosomal subunit protein eL29(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487078|imex:IM-26985-459 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENST00000381607|ensembl:ENSP00000371020|ensembl:ENST00000397959|ensembl:ENSP00000381050|ensembl:ENSP00000381053|ensembl:ENST00000509513|ensembl:ENSP00000424205|ensembl:ENST00000558098|ensembl:ENSP00000452959|ensembl:ENST00000602682|ensembl:ENSP00000473321|refseq:NP_001189396.1|refseq:NP_001189397.1|refseq:XP_016871076.1|refseq:XP_016871077.1|refseq:XP_016871078.1|refseq:XP_016871079.1|refseq:XP_016871081.1|refseq:XP_016871082.1|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0051607"(defense response to virus)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR035505|interpro:IPR036427|mint:Q15326|rcsb pdb:4NS5|rcsb pdb:5HDA|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000015171(gene)|ensembl:ENST00000381591(transcript)|ensembl:ENST00000381604(transcript)|ensembl:ENST00000397962(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:XP_005252416.1|refseq:NP_001189393.1|refseq:NP_001189394.1|refseq:NP_006615.2|refseq:NP_997644.2|refseq:XP_005252418.1|refseq:XP_005252419.1|refseq:XP_006717439.1 ensembl:ENST00000294189(transcript)|ensembl:ENST00000466397(transcript)|ensembl:ENST00000475248(transcript)|ensembl:ENST00000479017(transcript)|ensembl:ENST00000492277(transcript)|ensembl:ENST00000495383(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0007566"(embryo implantation)|go:"GO:0008201"(heparin binding)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR002673(Ribosomal protein L29e)|mint:P47914|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|ensembl:ENSG00000162244(gene)|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_000983.1|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339 - - comment:"author score: 11" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/QjUI+SjkfyB3GDHo7s09Sy1l4o9606 rogid:XZUSMDDzycAi6QEXYbljXaeVg0U9606 rigid:tgko+3sqcr3EX5ffvHMsShck6KY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15326 uniprotkb:P00505 intact:EBI-2623509|intact:EBI-28967957|ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENSP00000381053|intact:EBI-2799565|uniprotkb:B2R6G8|uniprotkb:B7Z293|uniprotkb:F6UH50|uniprotkb:Q2LD45|uniprotkb:Q2LD46|uniprotkb:Q2LD47|uniprotkb:Q2LD48|uniprotkb:Q5VUI1|uniprotkb:Q8N4B3 intact:EBI-720214|uniprotkb:Q9BWA3|uniprotkb:Q53FL3|intact:EBI-1058557|ensembl:ENSP00000245206|uniprotkb:B4DJA6|uniprotkb:E7ERW2 psi-mi:zmy11_human(display_long)|uniprotkb:BRAM1(gene name synonym)|uniprotkb:Bone morphogenetic protein receptor-associated molecule 1(gene name synonym)|uniprotkb:ZMYND11(gene name)|psi-mi:ZMYND11(display_short)|uniprotkb:Adenovirus 5 E1A-binding protein(gene name synonym)|uniprotkb:BS69(gene name synonym)|uniprotkb:Protein BS69(gene name synonym) psi-mi:aatm_human(display_long)|uniprotkb:Plasma membrane-associated fatty acid-binding protein(gene name synonym)|uniprotkb:Transaminase A(gene name synonym)|uniprotkb:Glutamate oxaloacetate transaminase 2(gene name synonym)|uniprotkb:Fatty acid-binding protein(gene name synonym)|uniprotkb:GOT2(gene name)|psi-mi:GOT2(display_short)|uniprotkb:Kynurenine aminotransferase 4(gene name synonym)|uniprotkb:Kynurenine aminotransferase IV(gene name synonym)|uniprotkb:Kynurenine--oxoglutarate transaminase 4(gene name synonym)|uniprotkb:Kynurenine--oxoglutarate transaminase IV(gene name synonym)|uniprotkb:KYAT4(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487078|imex:IM-26985-459 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENST00000381607|ensembl:ENSP00000371020|ensembl:ENST00000397959|ensembl:ENSP00000381050|ensembl:ENSP00000381053|ensembl:ENST00000509513|ensembl:ENSP00000424205|ensembl:ENST00000558098|ensembl:ENSP00000452959|ensembl:ENST00000602682|ensembl:ENSP00000473321|refseq:NP_001189396.1|refseq:NP_001189397.1|refseq:XP_016871076.1|refseq:XP_016871077.1|refseq:XP_016871078.1|refseq:XP_016871079.1|refseq:XP_016871081.1|refseq:XP_016871082.1|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0051607"(defense response to virus)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR035505|interpro:IPR036427|mint:Q15326|rcsb pdb:4NS5|rcsb pdb:5HDA|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000015171(gene)|ensembl:ENST00000381591(transcript)|ensembl:ENST00000381604(transcript)|ensembl:ENST00000397962(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:XP_005252416.1|refseq:NP_001189393.1|refseq:NP_001189394.1|refseq:NP_006615.2|refseq:NP_997644.2|refseq:XP_005252418.1|refseq:XP_005252419.1|refseq:XP_006717439.1 refseq:NP_001273149.1|refseq:NP_002071.2|ensembl:ENSG00000125166(gene)|ensembl:ENST00000245206(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004069"("L-aspartate:2-oxoglutarate aminotransferase activity")|go:"GO:0005543"(phospholipid binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005886"(plasma membrane)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006107"(oxaloacetate metabolic process)|go:"GO:0006531"(aspartate metabolic process)|go:"GO:0006532"(aspartate biosynthetic process)|go:"GO:0006533"(aspartate catabolic process)|go:"GO:0006536"(glutamate metabolic process)|go:"GO:0007565"(female pregnancy)|go:"GO:0007595"(lactation)|go:"GO:0009986"(cell surface)|go:"GO:0014850"(response to muscle activity)|go:"GO:0015908"(fatty acid transport)|go:"GO:0016212"(kynurenine-oxoglutarate transaminase activity)|go:"GO:0016597"(amino acid binding)|go:"GO:0019470"(4-hydroxyproline catabolic process)|go:"GO:0019550"(glutamate catabolic process to aspartate)|go:"GO:0019551"(glutamate catabolic process to 2-oxoglutarate)|go:"GO:0019899"(enzyme binding)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0030315"(T-tubule)|go:"GO:0031406"(carboxylic acid binding)|go:"GO:0032868"(response to insulin)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0043278"(response to morphine)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000796(Aspartate/other aminotransferase)|interpro:IPR004838(Aminotransferases, class-I, pyridoxal-phosphate-binding site)|interpro:IPR004839(Aminotransferase, class I and II)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015422(Pyridoxal phosphate-dependent transferase, major region, subdomain 2)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:P00505|rcsb pdb:5AX8|reactome:R-HSA-1614558|reactome:R-HSA-389661|reactome:R-HSA-70263|reactome:R-HSA-8963693|reactome:R-HSA-8964539 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/QjUI+SjkfyB3GDHo7s09Sy1l4o9606 rogid:O1J4G1Kh9QJP6udcrZYeIKiic/g9606 rigid:tgko+3sqcr3EX5ffvHMsShck6KY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15326 uniprotkb:Q9BX40 intact:EBI-2623509|intact:EBI-28967957|ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENSP00000381053|intact:EBI-2799565|uniprotkb:B2R6G8|uniprotkb:B7Z293|uniprotkb:F6UH50|uniprotkb:Q2LD45|uniprotkb:Q2LD46|uniprotkb:Q2LD47|uniprotkb:Q2LD48|uniprotkb:Q5VUI1|uniprotkb:Q8N4B3 intact:EBI-715641|uniprotkb:Q6PFW8|uniprotkb:Q96LH8|ensembl:ENSP00000279068 psi-mi:zmy11_human(display_long)|uniprotkb:BRAM1(gene name synonym)|uniprotkb:Bone morphogenetic protein receptor-associated molecule 1(gene name synonym)|uniprotkb:ZMYND11(gene name)|psi-mi:ZMYND11(display_short)|uniprotkb:Adenovirus 5 E1A-binding protein(gene name synonym)|uniprotkb:BS69(gene name synonym)|uniprotkb:Protein BS69(gene name synonym) psi-mi:ls14b_human(display_long)|uniprotkb:LSM14B(gene name)|psi-mi:LSM14B(display_short)|uniprotkb:C20orf40(gene name synonym)|uniprotkb:FAM61B(gene name synonym)|uniprotkb:RAP55B(gene name synonym)|uniprotkb:RNA-associated protein 55B(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487078|imex:IM-26985-459 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENST00000381607|ensembl:ENSP00000371020|ensembl:ENST00000397959|ensembl:ENSP00000381050|ensembl:ENSP00000381053|ensembl:ENST00000509513|ensembl:ENSP00000424205|ensembl:ENST00000558098|ensembl:ENSP00000452959|ensembl:ENST00000602682|ensembl:ENSP00000473321|refseq:NP_001189396.1|refseq:NP_001189397.1|refseq:XP_016871076.1|refseq:XP_016871077.1|refseq:XP_016871078.1|refseq:XP_016871079.1|refseq:XP_016871081.1|refseq:XP_016871082.1|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0051607"(defense response to virus)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR035505|interpro:IPR036427|mint:Q15326|rcsb pdb:4NS5|rcsb pdb:5HDA|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000015171(gene)|ensembl:ENST00000381591(transcript)|ensembl:ENST00000381604(transcript)|ensembl:ENST00000397962(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:XP_005252416.1|refseq:NP_001189393.1|refseq:NP_001189394.1|refseq:NP_006615.2|refseq:NP_997644.2|refseq:XP_005252418.1|refseq:XP_005252419.1|refseq:XP_006717439.1 refseq:NP_653304.2|ensembl:ENSG00000149657(gene)|ensembl:ENST00000279068(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0006417"(regulation of translation)|interpro:IPR010920(Like-Sm ribonucleoprotein-related, core)|interpro:IPR019050|interpro:IPR025609|interpro:IPR025761|interpro:IPR025762|interpro:IPR025768|mint:Q9BX40 - - comment:"author score: 12" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/QjUI+SjkfyB3GDHo7s09Sy1l4o9606 rogid:Rjc2jC3AM1IT1rizdT6MdR+gycY9606 rigid:tgko+3sqcr3EX5ffvHMsShck6KY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15326 uniprotkb:Q13283 intact:EBI-2623509|intact:EBI-28967957|ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENSP00000381053|intact:EBI-2799565|uniprotkb:B2R6G8|uniprotkb:B7Z293|uniprotkb:F6UH50|uniprotkb:Q2LD45|uniprotkb:Q2LD46|uniprotkb:Q2LD47|uniprotkb:Q2LD48|uniprotkb:Q5VUI1|uniprotkb:Q8N4B3 intact:EBI-1047359|intact:EBI-1384154|ensembl:ENSP00000348578|ensembl:ENSP00000377681|ensembl:ENSP00000430480|ensembl:ENSP00000502880|ensembl:ENSP00000503039|ensembl:ENSP00000503699|ensembl:ENSP00000503939|ensembl:ENSP00000504140|ensembl:ENSP00000504627|uniprotkb:Q5HYE9 psi-mi:zmy11_human(display_long)|uniprotkb:BRAM1(gene name synonym)|uniprotkb:Bone morphogenetic protein receptor-associated molecule 1(gene name synonym)|uniprotkb:ZMYND11(gene name)|psi-mi:ZMYND11(display_short)|uniprotkb:Adenovirus 5 E1A-binding protein(gene name synonym)|uniprotkb:BS69(gene name synonym)|uniprotkb:Protein BS69(gene name synonym) psi-mi:g3bp1_human(display_long)|uniprotkb:G3BP1(gene name)|psi-mi:G3BP1(display_short)|uniprotkb:G3BP(gene name synonym)|uniprotkb:ATP-dependent DNA helicase VIII(gene name synonym)|uniprotkb:GAP SH3 domain-binding protein 1(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487078|imex:IM-26985-459 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENST00000381607|ensembl:ENSP00000371020|ensembl:ENST00000397959|ensembl:ENSP00000381050|ensembl:ENSP00000381053|ensembl:ENST00000509513|ensembl:ENSP00000424205|ensembl:ENST00000558098|ensembl:ENSP00000452959|ensembl:ENST00000602682|ensembl:ENSP00000473321|refseq:NP_001189396.1|refseq:NP_001189397.1|refseq:XP_016871076.1|refseq:XP_016871077.1|refseq:XP_016871078.1|refseq:XP_016871079.1|refseq:XP_016871081.1|refseq:XP_016871082.1|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0051607"(defense response to virus)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR035505|interpro:IPR036427|mint:Q15326|rcsb pdb:4NS5|rcsb pdb:5HDA|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000015171(gene)|ensembl:ENST00000381591(transcript)|ensembl:ENST00000381604(transcript)|ensembl:ENST00000397962(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:XP_005252416.1|refseq:NP_001189393.1|refseq:NP_001189394.1|refseq:NP_006615.2|refseq:NP_997644.2|refseq:XP_005252418.1|refseq:XP_005252419.1|refseq:XP_006717439.1 refseq:NP_005745.1|refseq:NP_938405.1|ensembl:ENSG00000145907(gene)|go:"GO:0003729"(mRNA binding)|go:"GO:0004519"(endonuclease activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0033677"(DNA/RNA helicase activity)|go:"GO:0034063"(stress granule assembly)|go:"GO:0043204"(perikaryon)|go:"GO:0045087"(innate immune response)|go:"GO:0051607"(defense response to virus)|go:"GO:0062029"(positive regulation of stress granule assembly)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002075(Nuclear transport factor 2)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR018222|interpro:IPR032710|interpro:IPR034374|interpro:IPR034375|interpro:IPR035979|interpro:IPR039539|mint:Q13283|ensembl:ENST00000356245(transcript)|rcsb pdb:3Q90|rcsb pdb:4FCJ|rcsb pdb:4FCM|rcsb pdb:4IIA|rcsb pdb:5FW5|rcsb pdb:6TA7|ensembl:ENST00000394123(transcript)|ensembl:ENST00000522761(transcript)|ensembl:ENST00000676827(transcript)|ensembl:ENST00000676978(transcript)|ensembl:ENST00000677323(transcript)|ensembl:ENST00000678070(transcript)|ensembl:ENST00000678101(transcript)|ensembl:ENST00000678925(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|refseq:XP_006714812.1|refseq:XP_006714813.1|refseq:XP_016864411.1|refseq:XP_016864412.1 - - comment:"author score: 13" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/QjUI+SjkfyB3GDHo7s09Sy1l4o9606 rogid:0ZRCHNVEmmtGEOASNwg3kIm2uys9606 rigid:tgko+3sqcr3EX5ffvHMsShck6KY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15326 uniprotkb:Q7L2J0 intact:EBI-2623509|intact:EBI-28967957|ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENSP00000381053|intact:EBI-2799565|uniprotkb:B2R6G8|uniprotkb:B7Z293|uniprotkb:F6UH50|uniprotkb:Q2LD45|uniprotkb:Q2LD46|uniprotkb:Q2LD47|uniprotkb:Q2LD48|uniprotkb:Q5VUI1|uniprotkb:Q8N4B3 intact:EBI-2371983|uniprotkb:Q9NPD4|uniprotkb:B3KP86|uniprotkb:D6W5V7|ensembl:ENSP00000308546 psi-mi:zmy11_human(display_long)|uniprotkb:BRAM1(gene name synonym)|uniprotkb:Bone morphogenetic protein receptor-associated molecule 1(gene name synonym)|uniprotkb:ZMYND11(gene name)|psi-mi:ZMYND11(display_short)|uniprotkb:Adenovirus 5 E1A-binding protein(gene name synonym)|uniprotkb:BS69(gene name synonym)|uniprotkb:Protein BS69(gene name synonym) psi-mi:mepce_human(display_long)|uniprotkb:MEPCE(gene name)|psi-mi:MEPCE(display_short)|uniprotkb:BCDIN3(gene name synonym)|uniprotkb:Bicoid-interacting protein 3 homolog(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487078|imex:IM-26985-459 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENST00000381607|ensembl:ENSP00000371020|ensembl:ENST00000397959|ensembl:ENSP00000381050|ensembl:ENSP00000381053|ensembl:ENST00000509513|ensembl:ENSP00000424205|ensembl:ENST00000558098|ensembl:ENSP00000452959|ensembl:ENST00000602682|ensembl:ENSP00000473321|refseq:NP_001189396.1|refseq:NP_001189397.1|refseq:XP_016871076.1|refseq:XP_016871077.1|refseq:XP_016871078.1|refseq:XP_016871079.1|refseq:XP_016871081.1|refseq:XP_016871082.1|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0051607"(defense response to virus)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR035505|interpro:IPR036427|mint:Q15326|rcsb pdb:4NS5|rcsb pdb:5HDA|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000015171(gene)|ensembl:ENST00000381591(transcript)|ensembl:ENST00000381604(transcript)|ensembl:ENST00000397962(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:XP_005252416.1|refseq:NP_001189393.1|refseq:NP_001189394.1|refseq:NP_006615.2|refseq:NP_997644.2|refseq:XP_005252418.1|refseq:XP_005252419.1|refseq:XP_006717439.1 refseq:XP_011514712.1|refseq:NP_001181919.1|refseq:NP_001181920.1|refseq:NP_001181921.1|refseq:NP_062552.2|ensembl:ENSG00000146834(gene)|ensembl:ENST00000310512(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001510"(RNA methylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0008171"(O-methyltransferase activity)|go:"GO:0008173"(RNA methyltransferase activity)|go:"GO:0008757"(S-adenosylmethionine-dependent methyltransferase activity)|go:"GO:0016073"(snRNA metabolic process)|go:"GO:0017069"(snRNA binding)|go:"GO:0035562"(negative regulation of chromatin binding)|go:"GO:0040031"(snRNA modification)|go:"GO:0097322"(7SK snRNA binding)|go:"GO:0120259"(7SK snRNP)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1905382"(positive regulation of snRNA transcription by RNA polymerase II)|go:"GO:1990276"(RNA 5'-methyltransferase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR010675(Bicoid-interacting 3)|interpro:IPR024160|interpro:IPR025714|interpro:IPR029063|interpro:IPR039772|mint:Q7L2J0|rcsb pdb:5UNA|rcsb pdb:6DCB|rcsb pdb:6DCC - - comment:"author score: 14" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/QjUI+SjkfyB3GDHo7s09Sy1l4o9606 rogid:VGhJoO3FD7nsJPVSBsKuKsPJzEM9606 rigid:tgko+3sqcr3EX5ffvHMsShck6KY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15326 uniprotkb:Q9NWU5 intact:EBI-2623509|intact:EBI-28967957|ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENSP00000381053|intact:EBI-2799565|uniprotkb:B2R6G8|uniprotkb:B7Z293|uniprotkb:F6UH50|uniprotkb:Q2LD45|uniprotkb:Q2LD46|uniprotkb:Q2LD47|uniprotkb:Q2LD48|uniprotkb:Q5VUI1|uniprotkb:Q8N4B3 intact:EBI-5461867|uniprotkb:Q5H9Q1|uniprotkb:Q96Q51|uniprotkb:Q9P006|intact:EBI-6137918|uniprotkb:A6NGJ8|ensembl:ENSP00000431040 psi-mi:zmy11_human(display_long)|uniprotkb:BRAM1(gene name synonym)|uniprotkb:Bone morphogenetic protein receptor-associated molecule 1(gene name synonym)|uniprotkb:ZMYND11(gene name)|psi-mi:ZMYND11(display_short)|uniprotkb:Adenovirus 5 E1A-binding protein(gene name synonym)|uniprotkb:BS69(gene name synonym)|uniprotkb:Protein BS69(gene name synonym) psi-mi:rm22_human(display_long)|uniprotkb:MRPL22(gene name)|psi-mi:MRPL22(display_short)|uniprotkb:MRPL25(gene name synonym)|uniprotkb:RPML25(gene name synonym)|uniprotkb:39S ribosomal protein L25, mitochondrial(gene name synonym)|uniprotkb:HSPC158(orf name)|uniprotkb:Mitochondrial large ribosomal subunit protein uL22m(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487078|imex:IM-26985-459 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENST00000381607|ensembl:ENSP00000371020|ensembl:ENST00000397959|ensembl:ENSP00000381050|ensembl:ENSP00000381053|ensembl:ENST00000509513|ensembl:ENSP00000424205|ensembl:ENST00000558098|ensembl:ENSP00000452959|ensembl:ENST00000602682|ensembl:ENSP00000473321|refseq:NP_001189396.1|refseq:NP_001189397.1|refseq:XP_016871076.1|refseq:XP_016871077.1|refseq:XP_016871078.1|refseq:XP_016871079.1|refseq:XP_016871081.1|refseq:XP_016871082.1|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0051607"(defense response to virus)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR035505|interpro:IPR036427|mint:Q15326|rcsb pdb:4NS5|rcsb pdb:5HDA|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000015171(gene)|ensembl:ENST00000381591(transcript)|ensembl:ENST00000381604(transcript)|ensembl:ENST00000397962(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:XP_005252416.1|refseq:NP_001189393.1|refseq:NP_001189394.1|refseq:NP_006615.2|refseq:NP_997644.2|refseq:XP_005252418.1|refseq:XP_005252419.1|refseq:XP_006717439.1 refseq:NP_001014990.1|refseq:NP_054899.2|ensembl:ENSG00000082515(gene)|ensembl:ENST00000523037(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:0015934"(large ribosomal subunit)|go:"GO:0042255"(ribosome assembly)|rcsb pdb:6ZM6|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7ODR|rcsb pdb:7ODS|interpro:IPR001063(Ribosomal protein L22/L17)|interpro:IPR005727(Ribosomal protein L22, bacterial-type)|interpro:IPR036394|mint:Q9NWU5|rcsb pdb:3J7Y|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6ZM5|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276 - - comment:"author score: 17" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/QjUI+SjkfyB3GDHo7s09Sy1l4o9606 rogid:Nmwjb2QTu0IyJMS0SufI3PsBwmM9606 rigid:tgko+3sqcr3EX5ffvHMsShck6KY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15326 uniprotkb:P35544 intact:EBI-2623509|intact:EBI-28967957|ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENSP00000381053|intact:EBI-2799565|uniprotkb:B2R6G8|uniprotkb:B7Z293|uniprotkb:F6UH50|uniprotkb:Q2LD45|uniprotkb:Q2LD46|uniprotkb:Q2LD47|uniprotkb:Q2LD48|uniprotkb:Q5VUI1|uniprotkb:Q8N4B3 intact:EBI-1056647|uniprotkb:Q9H5V4|ensembl:ENSP00000431822|ensembl:ENSP00000434440|ensembl:ENSP00000435370 psi-mi:zmy11_human(display_long)|uniprotkb:BRAM1(gene name synonym)|uniprotkb:Bone morphogenetic protein receptor-associated molecule 1(gene name synonym)|uniprotkb:ZMYND11(gene name)|psi-mi:ZMYND11(display_short)|uniprotkb:Adenovirus 5 E1A-binding protein(gene name synonym)|uniprotkb:BS69(gene name synonym)|uniprotkb:Protein BS69(gene name synonym) psi-mi:ubim_human(display_long)|uniprotkb:FAU(gene name)|psi-mi:FAU(display_short) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487078|imex:IM-26985-459 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENST00000381607|ensembl:ENSP00000371020|ensembl:ENST00000397959|ensembl:ENSP00000381050|ensembl:ENSP00000381053|ensembl:ENST00000509513|ensembl:ENSP00000424205|ensembl:ENST00000558098|ensembl:ENSP00000452959|ensembl:ENST00000602682|ensembl:ENSP00000473321|refseq:NP_001189396.1|refseq:NP_001189397.1|refseq:XP_016871076.1|refseq:XP_016871077.1|refseq:XP_016871078.1|refseq:XP_016871079.1|refseq:XP_016871081.1|refseq:XP_016871082.1|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0051607"(defense response to virus)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR035505|interpro:IPR036427|mint:Q15326|rcsb pdb:4NS5|rcsb pdb:5HDA|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000015171(gene)|ensembl:ENST00000381591(transcript)|ensembl:ENST00000381604(transcript)|ensembl:ENST00000397962(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:XP_005252416.1|refseq:NP_001189393.1|refseq:NP_001189394.1|refseq:NP_006615.2|refseq:NP_997644.2|refseq:XP_005252418.1|refseq:XP_005252419.1|refseq:XP_006717439.1 refseq:NP_001988.1|ensembl:ENSG00000149806(gene)|ensembl:ENST00000527548(transcript)|ensembl:ENST00000529639(transcript)|ensembl:ENST00000531743(transcript)|go:"GO:0003723"(RNA binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR019956|interpro:IPR029071|interpro:IPR039415|mint:P35544|rcsb pdb:2L7R - - comment:"author score: 42" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/QjUI+SjkfyB3GDHo7s09Sy1l4o9606 rogid:LlvOcL+mfbwXRDzsmN+GtS2SCcc9606 rigid:tgko+3sqcr3EX5ffvHMsShck6KY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q15326 uniprotkb:Q96FJ2 intact:EBI-2623509|intact:EBI-28967957|ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENSP00000381053|intact:EBI-2799565|uniprotkb:B2R6G8|uniprotkb:B7Z293|uniprotkb:F6UH50|uniprotkb:Q2LD45|uniprotkb:Q2LD46|uniprotkb:Q2LD47|uniprotkb:Q2LD48|uniprotkb:Q5VUI1|uniprotkb:Q8N4B3 intact:EBI-742371|uniprotkb:B2R5B4|ensembl:ENSP00000477310 psi-mi:zmy11_human(display_long)|uniprotkb:BRAM1(gene name synonym)|uniprotkb:Bone morphogenetic protein receptor-associated molecule 1(gene name synonym)|uniprotkb:ZMYND11(gene name)|psi-mi:ZMYND11(display_short)|uniprotkb:Adenovirus 5 E1A-binding protein(gene name synonym)|uniprotkb:BS69(gene name synonym)|uniprotkb:Protein BS69(gene name synonym) psi-mi:dyl2_human(display_long)|uniprotkb:DYNLL2(gene name)|psi-mi:DYNLL2(display_short)|uniprotkb:Dynein light chain LC8-type 2(gene name synonym)|uniprotkb:DLC2(gene name synonym)|uniprotkb:8 kDa dynein light chain b(gene name synonym) psi-mi:"MI:0676"(tandem affinity purification) Marcon et al. (2014) doi:10.1016/j.celrep.2014.05.050|pubmed:24981860|imex:IM-26985 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-25487078|imex:IM-26985-459 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSP00000371003|ensembl:ENSP00000371017|ensembl:ENST00000381607|ensembl:ENSP00000371020|ensembl:ENST00000397959|ensembl:ENSP00000381050|ensembl:ENSP00000381053|ensembl:ENST00000509513|ensembl:ENSP00000424205|ensembl:ENST00000558098|ensembl:ENSP00000452959|ensembl:ENST00000602682|ensembl:ENSP00000473321|refseq:NP_001189396.1|refseq:NP_001189397.1|refseq:XP_016871076.1|refseq:XP_016871077.1|refseq:XP_016871078.1|refseq:XP_016871079.1|refseq:XP_016871081.1|refseq:XP_016871082.1|go:"GO:0046329"(negative regulation of JNK cascade)|go:"GO:0051607"(defense response to virus)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000313(PWWP)|interpro:IPR001487(Bromodomain)|interpro:IPR001965(Zinc finger, PHD-type)|interpro:IPR002893(Zinc finger, MYND-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR019786|interpro:IPR019787|interpro:IPR035505|interpro:IPR036427|mint:Q15326|rcsb pdb:4NS5|rcsb pdb:5HDA|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|ensembl:ENSG00000015171(gene)|ensembl:ENST00000381591(transcript)|ensembl:ENST00000381604(transcript)|ensembl:ENST00000397962(transcript)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0006325"(chromatin organization)|go:"GO:0007049"(cell cycle)|go:"GO:0008270"(zinc ion binding)|go:"GO:0034243"(regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0035064"(methylated histone binding)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|refseq:XP_005252416.1|refseq:NP_001189393.1|refseq:NP_001189394.1|refseq:NP_006615.2|refseq:NP_997644.2|refseq:XP_005252418.1|refseq:XP_005252419.1|refseq:XP_006717439.1 go:"GO:0005813"(centrosome)|refseq:NP_542408.1|ensembl:ENSG00000264364(gene)|ensembl:ENST00000579991(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0007017"(microtubule-based process)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0030286"(dynein complex)|go:"GO:0031475"(myosin V complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097542"(ciliary tip)|go:"GO:0097731"(9+0 non-motile cilium)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:Q96FJ2|rcsb pdb:2XQQ|rcsb pdb:3P8M|rcsb pdb:4D07|reactome:R-HSA-139910|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-3371497|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025 - - comment:"author score: 53" figure legend:ST4|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293)|taxid:9606(Homo sapiens transformed primary embryonal kidney cells) - 2020/02/06 2020/03/31 rogid:/QjUI+SjkfyB3GDHo7s09Sy1l4o9606 rogid:4RFpJF40RBja5mOvt/aCv3miiDU9606 rigid:tgko+3sqcr3EX5ffvHMsShck6KY false tandem tag:n-n - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification)